locus-tag	class	description
AVT04_RS00040	COG1523	belongs to the glycosyl hydrolase 13 family
AVT04_RS00050	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVT04_RS00055	COG4605	iron ion homeostasis
AVT04_RS00060	COG4604	ABC transporter, ATP-binding protein
AVT04_RS00065	COG4607	ABC-type enterochelin transport system periplasmic component
AVT04_RS00070	COG2822	iron ion transport
AVT04_RS00075	COG2837	iron assimilation
AVT04_RS00080	COG0672	)-iron permease
AVT04_RS00085	COG0805	protein transport
AVT04_RS00090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVT04_RS00110	COG1609	Transcriptional regulator
AVT04_RS00115	COG1640	4-alpha-glucanotransferase
AVT04_RS00120	COG0058	SHG alpha-glucan phosphorylase activity
AVT04_RS00135	COG0095	Lipoate-protein ligase
AVT04_RS00150	COG0704	Plays a role in the regulation of phosphate uptake
AVT04_RS00165	COG0581	inorganic phosphate transmembrane transporter activity
AVT04_RS00170	COG0573	inorganic phosphate transmembrane transporter activity
AVT04_RS00180	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AVT04_RS00180	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVT04_RS00185	COG0483	inositol monophosphate 1-phosphatase activity
AVT04_RS00195	COG1393	Belongs to the ArsC family
AVT04_RS00200	COG0196	riboflavin kinase activity
AVT04_RS00235	COG2873	o-acetylhomoserine
AVT04_RS00245	COG1115	amino acid carrier protein
AVT04_RS00265	COG0737	Belongs to the 5'-nucleotidase family
AVT04_RS00285	COG0154	amidase activity
AVT04_RS00295	COG3104	oligopeptide transport
AVT04_RS00325	COG1567	CRISPR-associated RAMP protein, Csm4 family
AVT04_RS00330	COG1337	RAMP superfamily
AVT04_RS00350	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AVT04_RS00365	COG0167	dihydroorotate dehydrogenase activity
AVT04_RS00375	COG0047	phosphoribosylformylglycinamidine synthase activity
AVT04_RS00385	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AVT04_RS00395	COG0534	Mate efflux family protein
AVT04_RS00440	COG1063	alcohol dehydrogenase
AVT04_RS00450	COG1230	cation diffusion facilitator family transporter
AVT04_RS00490	COG3527	Alpha-acetolactate decarboxylase
AVT04_RS00495	COG0028	Belongs to the TPP enzyme family
AVT04_RS00505	COG0010	Belongs to the arginase family
AVT04_RS00510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AVT04_RS00520	COG1396	sequence-specific DNA binding
AVT04_RS00555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVT04_RS00560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AVT04_RS00595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AVT04_RS00600	COG0758	DNA mediated transformation
AVT04_RS00605	COG1940	carbohydrate kinase activity
AVT04_RS00615	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AVT04_RS00625	COG1827	regulation of RNA biosynthetic process
AVT04_RS00635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AVT04_RS00645	COG2188	Transcriptional regulator
AVT04_RS00650	COG0519	Catalyzes the synthesis of GMP from XMP
AVT04_RS00650	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AVT04_RS00660	COG3421	Type III restriction
AVT04_RS00670	COG1064	alcohol dehydrogenase
AVT04_RS00675	COG1064	alcohol dehydrogenase
AVT04_RS00680	COG1064	alcohol dehydrogenase
AVT04_RS00695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVT04_RS00700	COG1126	abc transporter atp-binding protein
AVT04_RS00705	COG0765	amino acid transport
AVT04_RS00710	COG2824	Alkylphosphonate utilization operon protein PhnA
AVT04_RS00715	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVT04_RS00730	COG1705	Flagellar rod assembly protein muramidase FlgJ
AVT04_RS00730	COG3942	CHAP domain
AVT04_RS00765	COG0803	Belongs to the bacterial solute-binding protein 9 family
AVT04_RS00765	COG3443	Belongs to the bacterial solute-binding protein 9 family
AVT04_RS00785	COG4975	Glucose uptake
AVT04_RS00810	COG3328	transposase activity
AVT04_RS00820	COG0626	cystathionine gamma-synthase activity
AVT04_RS00825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AVT04_RS00835	COG3328	transposase activity
AVT04_RS00840	COG2217	Heavy metal translocating P-type atpase
AVT04_RS00845	COG3328	transposase activity
AVT04_RS00855	COG1278	Cold shock
AVT04_RS00905	COG0720	synthase
AVT04_RS00915	COG0251	oxidation-reduction process
AVT04_RS00945	COG0436	Aminotransferase
AVT04_RS00955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AVT04_RS00955	COG1199	ATP-dependent helicase activity
AVT04_RS00965	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVT04_RS00970	COG4603	Belongs to the binding-protein-dependent transport system permease family
AVT04_RS00975	COG3845	ABC transporter
AVT04_RS00980	COG1744	ABC transporter substrate-binding protein PnrA-like
AVT04_RS01000	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AVT04_RS01005	COG2813	Specifically methylates the guanine in position
AVT04_RS01025	COG2801	Transposase and inactivated derivatives
AVT04_RS01030	COG5002	protein histidine kinase activity
AVT04_RS01035	COG5002	protein histidine kinase activity
AVT04_RS01060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AVT04_RS01065	COG4684	Psort location CytoplasmicMembrane, score
AVT04_RS01070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVT04_RS01090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVT04_RS01095	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AVT04_RS01115	COG2801	Transposase and inactivated derivatives
AVT04_RS01120	COG2801	Transposase and inactivated derivatives
AVT04_RS01125	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AVT04_RS01135	COG1696	Membrane protein involved in D-alanine export
AVT04_RS01150	COG1132	(ABC) transporter
AVT04_RS01180	COG2890	protein-(glutamine-N5) methyltransferase activity
AVT04_RS01195	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AVT04_RS01200	COG0625	glutathione transferase activity
AVT04_RS01205	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AVT04_RS01240	COG3599	regulation of cell shape
AVT04_RS01260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AVT04_RS01270	COG0849	cell division
AVT04_RS01295	COG1217	gtp-binding protein TYPA
AVT04_RS01300	COG1940	carbohydrate kinase activity
AVT04_RS01305	COG4483	Protein conserved in bacteria
AVT04_RS01310	COG0735	belongs to the Fur family
AVT04_RS01315	COG0783	Belongs to the Dps family
AVT04_RS01320	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AVT04_RS01330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AVT04_RS01360	COG1704	LemA family
AVT04_RS01390	COG0732	type I restriction modification DNA specificity domain
AVT04_RS01405	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AVT04_RS01410	COG4221	oxidoreductase activity
AVT04_RS01440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AVT04_RS01445	COG0406	alpha-ribazole phosphatase activity
AVT04_RS01525	COG0494	nUDIX hydrolase
AVT04_RS01535	COG1914	H( )-stimulated, divalent metal cation uptake system
AVT04_RS01540	COG4443	Transcriptional Coactivator p15 (PC4)
AVT04_RS01550	COG1268	BioY protein
AVT04_RS01555	COG0826	peptidase U32
AVT04_RS01580	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AVT04_RS01600	COG2183	response to ionizing radiation
AVT04_RS01605	COG0701	Predicted permease
AVT04_RS01610	COG3689	TIGRFAM TIGR03943 family protein
AVT04_RS01620	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AVT04_RS01625	COG1518	maintenance of DNA repeat elements
AVT04_RS01685	COG0077	Prephenate dehydratase
AVT04_RS01710	COG0287	Prephenate dehydrogenase
AVT04_RS01735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AVT04_RS01740	COG1368	sulfuric ester hydrolase activity
AVT04_RS01765	COG1609	Transcriptional regulator
AVT04_RS01770	COG0006	proline dipeptidase activity
AVT04_RS01775	COG1185	polyribonucleotide nucleotidyltransferase activity
AVT04_RS01790	COG0557	exoribonuclease II activity
AVT04_RS01800	COG2814	Major facilitator Superfamily
AVT04_RS01805	COG0237	dephospho-CoA kinase activity
AVT04_RS01815	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AVT04_RS01820	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AVT04_RS01830	COG3711	transcriptional antiterminator
AVT04_RS01840	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AVT04_RS01845	COG0768	penicillin binding
AVT04_RS01850	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AVT04_RS01855	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AVT04_RS01885	COG0765	amino acid transport
AVT04_RS01890	COG4703	Protein of unknown function (DUF1797)
AVT04_RS01895	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AVT04_RS01900	COG0542	response to heat
AVT04_RS01905	COG0494	nUDIX hydrolase
AVT04_RS01925	COG0673	inositol 2-dehydrogenase activity
AVT04_RS01960	COG0539	negative regulation of cytoplasmic translation
AVT04_RS01980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVT04_RS01990	COG0187	DNA topoisomerase II activity
AVT04_RS02010	COG2040	homocysteine
AVT04_RS02015	COG0833	amino acid
AVT04_RS02030	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AVT04_RS02040	COG3425	synthase
AVT04_RS02050	COG1272	protein, Hemolysin III
AVT04_RS02080	COG0438	transferase activity, transferring glycosyl groups
AVT04_RS02145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVT04_RS02150	COG0686	Belongs to the AlaDH PNT family
AVT04_RS02155	COG0686	Belongs to the AlaDH PNT family
AVT04_RS02160	COG1473	amidohydrolase
AVT04_RS02165	COG1187	pseudouridine synthase activity
AVT04_RS02200	COG1131	(ABC) transporter
AVT04_RS02210	COG3279	Response regulator of the LytR AlgR family
AVT04_RS02250	COG0577	efflux transmembrane transporter activity
AVT04_RS02255	COG0577	efflux transmembrane transporter activity
AVT04_RS02290	COG0505	Belongs to the CarA family
AVT04_RS02310	COG0564	pseudouridine synthase activity
AVT04_RS02320	COG0583	DNA-binding transcription factor activity
AVT04_RS02355	COG1263	PTS System
AVT04_RS02355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVT04_RS02355	COG2190	(PTS) system
AVT04_RS02365	COG1113	amino acid transport
AVT04_RS02420	COG1388	LysM domain
AVT04_RS02420	COG1705	Flagellar rod assembly protein muramidase FlgJ
AVT04_RS02425	COG0347	Belongs to the P(II) protein family
AVT04_RS02430	COG0004	ammonium transporteR
AVT04_RS02440	COG4467	Involved in initiation control of chromosome replication
AVT04_RS02445	COG1774	PSP1 C-terminal conserved region
AVT04_RS02450	COG0470	DNA polymerase III
AVT04_RS02470	COG0772	Belongs to the SEDS family
AVT04_RS02505	COG0356	it plays a direct role in the translocation of protons across the membrane
AVT04_RS02540	COG2962	Rard protein
AVT04_RS02555	COG0726	polysaccharide deacetylase
AVT04_RS02560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVT04_RS02565	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AVT04_RS02580	COG0436	Aminotransferase
AVT04_RS02585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVT04_RS02610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVT04_RS02615	COG4122	O-methyltransferase activity
AVT04_RS02645	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVT04_RS02645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVT04_RS02665	COG1702	phosphate starvation-inducible protein PhoH
AVT04_RS02730	COG0242	peptide deformylase activity
AVT04_RS02735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AVT04_RS02755	COG0488	(ABC) transporter
AVT04_RS02825	COG1104	cysteine desulfurase activity
AVT04_RS02835	COG0285	dihydrofolate synthase activity
AVT04_RS02840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVT04_RS02850	COG1105	Belongs to the carbohydrate kinase PfkB family
AVT04_RS02855	COG1349	DNA-binding transcription factor activity
AVT04_RS02895	COG0439	Biotin carboxylase
AVT04_RS02910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVT04_RS02915	COG1028	Short-chain dehydrogenase reductase Sdr
AVT04_RS02920	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AVT04_RS02940	COG1846	Transcriptional regulator
AVT04_RS02945	COG1024	Enoyl-CoA hydratase
AVT04_RS02950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVT04_RS02955	COG0527	aspartate kinase activity
AVT04_RS03050	COG1040	competence protein
AVT04_RS03055	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AVT04_RS03060	COG1739	Uncharacterized protein family UPF0029
AVT04_RS03075	COG0517	IMP dehydrogenase activity
AVT04_RS03095	COG0559	Belongs to the binding-protein-dependent transport system permease family
AVT04_RS03105	COG4471	UPF0298 protein
AVT04_RS03130	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AVT04_RS03135	COG0626	cystathionine gamma-synthase activity
AVT04_RS03145	COG2244	polysaccharide biosynthetic process
AVT04_RS03165	COG1611	Belongs to the LOG family
AVT04_RS03185	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AVT04_RS03190	COG0195	Participates in both transcription termination and antitermination
AVT04_RS03200	COG1316	TRANSCRIPTIONal
AVT04_RS03205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVT04_RS03210	COG0802	atpase or kinase
AVT04_RS03215	COG2252	PERMEase
AVT04_RS03220	COG0561	phosphatase activity
AVT04_RS03225	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AVT04_RS03235	COG3715	PTS system
AVT04_RS03240	COG3716	PTS system mannose fructose sorbose family IID component
AVT04_RS03265	COG1132	(ABC) transporter
AVT04_RS03280	COG1484	DNA-dependent DNA replication
AVT04_RS03295	COG5002	protein histidine kinase activity
AVT04_RS03300	COG0745	RESPONSE REGULATOR receiver
AVT04_RS03315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AVT04_RS03325	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AVT04_RS03335	COG1122	ATPase activity
AVT04_RS03350	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AVT04_RS03370	COG1464	Belongs to the NlpA lipoprotein family
AVT04_RS03375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVT04_RS03380	COG1122	ATPase activity
AVT04_RS03390	COG0310	cobalt ion transport
AVT04_RS03445	COG2274	protein secretion by the type I secretion system
AVT04_RS03450	COG2274	protein secretion by the type I secretion system
AVT04_RS03455	COG2274	protein secretion by the type I secretion system
AVT04_RS03460	COG2274	protein secretion by the type I secretion system
AVT04_RS03475	COG0671	phosphoesterase, PA-phosphatase related
AVT04_RS03480	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AVT04_RS03490	COG0569	domain protein
AVT04_RS03495	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AVT04_RS03505	COG1187	pseudouridine synthase activity
AVT04_RS03580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVT04_RS03585	COG1254	Belongs to the acylphosphatase family
AVT04_RS03595	COG2801	Transposase and inactivated derivatives
AVT04_RS03610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AVT04_RS03630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AVT04_RS03645	COG0116	Belongs to the methyltransferase superfamily
AVT04_RS03670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AVT04_RS03675	COG3579	cysteine-type endopeptidase activity
AVT04_RS03690	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AVT04_RS03720	COG1349	DNA-binding transcription factor activity
AVT04_RS03745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AVT04_RS03750	COG0564	pseudouridine synthase activity
AVT04_RS03765	COG2801	Transposase and inactivated derivatives
AVT04_RS03795	COG1116	anion transmembrane transporter activity
AVT04_RS03795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVT04_RS03800	COG4120	Belongs to the binding-protein-dependent transport system permease family
AVT04_RS03815	COG4589	Belongs to the CDS family
AVT04_RS03845	COG1263	PTS System
AVT04_RS03845	COG2190	(PTS) system
AVT04_RS03845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVT04_RS03850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVT04_RS03850	COG2190	(PTS) system
AVT04_RS03850	COG1263	PTS System
AVT04_RS03855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVT04_RS03855	COG1263	PTS System
AVT04_RS03855	COG2190	(PTS) system
AVT04_RS03860	COG1263	PTS System
AVT04_RS03860	COG2190	(PTS) system
AVT04_RS03860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVT04_RS03870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AVT04_RS03875	COG1121	(ABC) transporter
AVT04_RS03900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVT04_RS03915	COG4608	Belongs to the ABC transporter superfamily
AVT04_RS03920	COG0444	Belongs to the ABC transporter superfamily
AVT04_RS03925	COG0444	Belongs to the ABC transporter superfamily
AVT04_RS03940	COG0601	transmembrane transport
AVT04_RS03950	COG0719	Fe-S assembly protein
AVT04_RS03960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVT04_RS03965	COG0719	Fe-S assembly protein
AVT04_RS03975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AVT04_RS03980	COG4862	establishment of competence for transformation
AVT04_RS03985	COG1968	undecaprenyl-diphosphatase activity
AVT04_RS03990	COG0765	amino acid transport
AVT04_RS03995	COG1126	abc transporter atp-binding protein
AVT04_RS04025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AVT04_RS04060	COG0737	Belongs to the 5'-nucleotidase family
AVT04_RS04065	COG0737	Belongs to the 5'-nucleotidase family
AVT04_RS04080	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AVT04_RS04100	COG0504	CTP synthase activity
AVT04_RS04115	COG0668	transmembrane transport
AVT04_RS04130	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVT04_RS04155	COG4166	transmembrane transport
AVT04_RS04255	COG0351	phosphomethylpyrimidine kinase
AVT04_RS04290	COG1876	peptidase activity
AVT04_RS04295	COG0588	phosphoglycerate mutase activity
AVT04_RS04305	COG3830	Belongs to the UPF0237 family
AVT04_RS04330	COG1705	Flagellar rod assembly protein muramidase FlgJ
AVT04_RS04330	COG3942	CHAP domain
AVT04_RS04390	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AVT04_RS04415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVT04_RS04425	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AVT04_RS04435	COG1045	serine acetyltransferase
AVT04_RS04450	COG1686	Belongs to the peptidase S11 family
AVT04_RS04460	COG0542	response to heat
AVT04_RS04465	COG4463	regulation of RNA biosynthetic process
AVT04_RS04490	COG1619	proteins homologs of microcin C7 resistance protein MccF
AVT04_RS04505	COG2801	Transposase and inactivated derivatives
AVT04_RS04510	COG0431	NADPH-dependent FMN reductase
AVT04_RS04525	COG2309	aminopeptidase activity
AVT04_RS04615	COG1393	Belongs to the ArsC family
AVT04_RS04670	COG4550	Control of competence regulator ComK, YlbF/YmcA
AVT04_RS04685	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AVT04_RS04705	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AVT04_RS04710	COG0151	Belongs to the GarS family
AVT04_RS04735	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AVT04_RS04750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVT04_RS04760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVT04_RS04775	COG0436	Aminotransferase
AVT04_RS04795	COG3942	CHAP domain
AVT04_RS04915	COG2801	Transposase and inactivated derivatives
AVT04_RS04935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVT04_RS04965	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AVT04_RS04970	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AVT04_RS04980	COG0012	GTP binding
AVT04_RS04990	COG0592	DNA-directed DNA polymerase activity
AVT04_RS05000	COG1475	DNA binding
AVT04_RS05005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVT04_RS05040	COG0488	(ABC) transporter
AVT04_RS05045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AVT04_RS05085	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AVT04_RS05100	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AVT04_RS05105	COG3584	3D domain protein
AVT04_RS05105	COG1388	LysM domain
AVT04_RS05110	COG0741	lytic transglycosylase activity
AVT04_RS05140	COG0305	Participates in initiation and elongation during chromosome replication
AVT04_RS05155	COG3759	membrane
AVT04_RS05165	COG1511	domain protein
AVT04_RS05165	COG1511	domain protein
AVT04_RS05190	COG3237	CsbD-like
AVT04_RS05205	COG2261	transglycosylase associated protein
AVT04_RS05220	COG1597	lipid kinase activity
AVT04_RS05235	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AVT04_RS05245	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AVT04_RS05250	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AVT04_RS05270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AVT04_RS05280	COG0602	queuosine metabolic process
AVT04_RS05290	COG1328	CTP reductase activity
AVT04_RS05320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AVT04_RS05355	COG1132	(ABC) transporter
AVT04_RS05365	COG1396	sequence-specific DNA binding
AVT04_RS05370	COG1132	(ABC) transporter
AVT04_RS05375	COG0515	serine threonine protein kinase
AVT04_RS05390	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AVT04_RS05535	COG0201	protein transport
AVT04_RS05600	COG0191	fructose-bisphosphate aldolase activity
AVT04_RS05630	COG2188	Transcriptional regulator
AVT04_RS05635	COG1609	Transcriptional regulator
AVT04_RS05645	COG0366	Alpha amylase catalytic
AVT04_RS05650	COG0366	Alpha amylase catalytic
AVT04_RS05655	COG3590	peptidase
AVT04_RS05660	COG1454	alcohol dehydrogenase
AVT04_RS05660	COG1012	belongs to the aldehyde dehydrogenase family
AVT04_RS05670	COG1012	belongs to the aldehyde dehydrogenase family
AVT04_RS05670	COG1454	alcohol dehydrogenase
AVT04_RS05695	COG0534	Mate efflux family protein
AVT04_RS05705	COG1461	Dihydroxyacetone kinase
AVT04_RS05710	COG0129	dihydroxy-acid dehydratase activity
AVT04_RS05715	COG0028	Belongs to the TPP enzyme family
AVT04_RS05720	COG0440	acetolactate synthase activity
AVT04_RS05735	COG4499	WXG100 protein secretion system (Wss), protein YukC
AVT04_RS05735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AVT04_RS05755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVT04_RS05760	COG1459	type II secretion system
AVT04_RS05815	COG1266	CAAX protease self-immunity
AVT04_RS05820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AVT04_RS05825	COG1363	Peptidase, m42
AVT04_RS05835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AVT04_RS05840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVT04_RS05845	COG2391	methyltransferase activity
AVT04_RS05850	COG0425	Belongs to the sulfur carrier protein TusA family
AVT04_RS05880	COG2226	methyltransferase
AVT04_RS05900	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AVT04_RS05905	COG0457	Tetratricopeptide repeat
AVT04_RS05905	COG0705	Rhomboid family
AVT04_RS05910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AVT04_RS05945	COG0756	dUTP diphosphatase activity
AVT04_RS05985	COG4166	transmembrane transport
AVT04_RS05990	COG4166	transmembrane transport
AVT04_RS06015	COG0706	membrane insertase activity
AVT04_RS06075	COG3118	belongs to the thioredoxin family
AVT04_RS06080	COG1832	CoA-binding protein
AVT04_RS06085	COG0084	hydrolase, TatD family'
AVT04_RS06130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVT04_RS06155	COG2801	Transposase and inactivated derivatives
AVT04_RS06190	COG0789	Transcriptional regulator
AVT04_RS06195	COG0174	glutamine synthetase
AVT04_RS06215	COG1214	PFAM Peptidase M22, glycoprotease
AVT04_RS06220	COG0456	acetyltransferase
AVT04_RS06240	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVT04_RS06245	COG0681	Belongs to the peptidase S26 family
AVT04_RS06270	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVT04_RS06270	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVT04_RS06365	COG0006	proline dipeptidase activity
AVT04_RS06370	COG2131	deaminase
AVT04_RS06395	COG1621	beta-fructofuranosidase activity
AVT04_RS06400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVT04_RS06400	COG2190	(PTS) system
AVT04_RS06400	COG1263	PTS System
AVT04_RS06405	COG1940	carbohydrate kinase activity
AVT04_RS06410	COG1482	cell wall glycoprotein biosynthetic process
AVT04_RS06425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AVT04_RS06430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AVT04_RS06445	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AVT04_RS06450	COG0252	asparaginase activity
AVT04_RS06455	COG0561	phosphatase activity
AVT04_RS06485	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AVT04_RS06525	COG3152	Membrane
AVT04_RS06560	COG0768	penicillin binding
AVT04_RS06570	COG0513	Belongs to the DEAD box helicase family
AVT04_RS06575	COG0737	Belongs to the 5'-nucleotidase family
AVT04_RS06580	COG4470	Protein conserved in bacteria
AVT04_RS06600	COG1132	(ABC) transporter
AVT04_RS06605	COG1132	(ABC) transporter
AVT04_RS06610	COG2274	protein secretion by the type I secretion system
AVT04_RS06640	COG2801	Transposase and inactivated derivatives
AVT04_RS06660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AVT04_RS06680	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AVT04_RS06690	COG4619	ABC transporter
AVT04_RS06695	COG0390	transport system, permease component
AVT04_RS06735	COG1882	Formate acetyltransferase
AVT04_RS06750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVT04_RS06760	COG1126	abc transporter atp-binding protein
AVT04_RS06770	COG0492	ferredoxin-NADP+ reductase activity
AVT04_RS06775	COG0742	ribosomal rna small subunit methyltransferase
AVT04_RS06780	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AVT04_RS06785	COG3480	Lon protease (S16) C-terminal proteolytic domain
AVT04_RS06790	COG1242	4 iron, 4 sulfur cluster binding
AVT04_RS06795	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AVT04_RS06805	COG0025	NhaP-type Na H and K H
AVT04_RS06810	COG1119	ATPase activity
AVT04_RS06815	COG1253	flavin adenine dinucleotide binding
AVT04_RS06820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AVT04_RS06835	COG0589	response to stress
AVT04_RS06840	COG0436	Aminotransferase
AVT04_RS06850	COG1335	isochorismatase
AVT04_RS06900	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AVT04_RS06905	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AVT04_RS06910	COG1534	Rna-binding protein
AVT04_RS06915	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AVT04_RS06920	COG1713	HD superfamily hydrolase involved in NAD metabolism
AVT04_RS06925	COG0799	negative regulation of ribosome biogenesis
AVT04_RS06930	COG2226	methyltransferase
AVT04_RS06960	COG0537	adenosine 5'-monophosphoramidase activity
AVT04_RS06965	COG1131	(ABC) transporter
AVT04_RS06990	COG2081	HI0933 family
AVT04_RS07000	COG2151	metal-sulfur cluster biosynthetic enzyme
AVT04_RS07010	COG2176	DNA-directed DNA polymerase activity
AVT04_RS07035	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AVT04_RS07045	COG0287	Prephenate dehydrogenase
AVT04_RS07045	COG1605	Chorismate mutase
AVT04_RS07050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVT04_RS07055	COG0512	Glutamine amidotransferase of anthranilate synthase
AVT04_RS07070	COG0135	phosphoribosylanthranilate isomerase activity
AVT04_RS07090	COG2217	Heavy metal translocating P-type atpase
AVT04_RS07100	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVT04_RS07105	COG0765	amino acid transport
AVT04_RS07110	COG0765	amino acid transport
AVT04_RS07115	COG1126	abc transporter atp-binding protein
AVT04_RS07120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVT04_RS07135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AVT04_RS07150	COG2211	Major facilitator Superfamily
AVT04_RS07155	COG1396	sequence-specific DNA binding
AVT04_RS07175	COG0513	Belongs to the DEAD box helicase family
AVT04_RS07185	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AVT04_RS07190	COG0726	polysaccharide deacetylase
AVT04_RS07200	COG0204	Acyl-transferase
AVT04_RS07205	COG1596	polysaccharide export
AVT04_RS07205	COG1555	photosystem II stabilization
AVT04_RS07210	COG2333	competence protein COMEC
AVT04_RS07210	COG0658	competence protein
AVT04_RS07225	COG4109	DRTGG domain
AVT04_RS07230	COG0024	Methionine aminopeptidase
AVT04_RS07240	COG4708	membrane
AVT04_RS07250	COG1597	lipid kinase activity
AVT04_RS07265	COG0708	Exodeoxyribonuclease III
AVT04_RS07270	COG3615	Tellurite resistance protein tehB
AVT04_RS07270	COG0500	methyltransferase
AVT04_RS07280	COG1837	Belongs to the UPF0109 family
AVT04_RS07285	COG0285	dihydrofolate synthase activity
AVT04_RS07290	COG0531	amino acid
AVT04_RS07330	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVT04_RS07335	COG1177	transmembrane transport
AVT04_RS07370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVT04_RS07380	COG1393	Belongs to the ArsC family
AVT04_RS07390	COG1380	Effector of murein hydrolase LrgA
AVT04_RS07395	COG1346	cytolysis
AVT04_RS07405	COG0187	DNA topoisomerase II activity
AVT04_RS07415	COG0560	Phosphoserine phosphatase
AVT04_RS07445	COG1132	(ABC) transporter
AVT04_RS07480	COG1187	pseudouridine synthase activity
AVT04_RS07495	COG1126	abc transporter atp-binding protein
AVT04_RS07500	COG0765	amino acid transport
AVT04_RS07525	COG1051	belongs to the nudix hydrolase family
AVT04_RS07530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVT04_RS07535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVT04_RS07540	COG0436	Aminotransferase
AVT04_RS07545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVT04_RS07560	COG0358	DNA primase activity
AVT04_RS07565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVT04_RS07570	COG2151	metal-sulfur cluster biosynthetic enzyme
AVT04_RS07575	COG0463	Glycosyl transferase, family 2
AVT04_RS07580	COG1091	dTDP-4-dehydrorhamnose reductase activity
AVT04_RS07590	COG1216	Glycosyl transferase, family 2
AVT04_RS07620	COG1215	transferase activity, transferring glycosyl groups
AVT04_RS07655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AVT04_RS07670	COG1104	cysteine desulfurase activity
AVT04_RS07685	COG2357	RelA SpoT domain protein
AVT04_RS07695	COG0564	pseudouridine synthase activity
AVT04_RS07700	COG0280	phosphate acetyltransferase
AVT04_RS07710	COG2801	Transposase and inactivated derivatives
AVT04_RS07715	COG2223	nitrite transmembrane transporter activity
AVT04_RS07720	COG0084	hydrolase, TatD family'
AVT04_RS07725	COG4608	Belongs to the ABC transporter superfamily
AVT04_RS07730	COG4166	transmembrane transport
AVT04_RS07740	COG4166	transmembrane transport
AVT04_RS07745	COG0601	transmembrane transport
AVT04_RS07750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVT04_RS07755	COG0444	Belongs to the ABC transporter superfamily
AVT04_RS07760	COG4608	Belongs to the ABC transporter superfamily
AVT04_RS07770	COG1131	(ABC) transporter
AVT04_RS07775	COG1725	Transcriptional regulator
AVT04_RS07780	COG0561	phosphatase activity
AVT04_RS07785	COG0561	phosphatase activity
AVT04_RS07790	COG0552	protein localization to endoplasmic reticulum
AVT04_RS07805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AVT04_RS07815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVT04_RS07815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVT04_RS07825	COG2815	serine threonine protein kinase
AVT04_RS07825	COG0515	serine threonine protein kinase
AVT04_RS07835	COG4585	Histidine kinase
AVT04_RS07840	COG2197	response regulator
AVT04_RS07900	COG0488	(ABC) transporter
AVT04_RS07920	COG1609	Transcriptional regulator
AVT04_RS07935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AVT04_RS07940	COG2017	converts alpha-aldose to the beta-anomer
AVT04_RS07945	COG2211	Major facilitator Superfamily
AVT04_RS07945	COG2190	(PTS) system
AVT04_RS07950	COG3250	beta-galactosidase activity
AVT04_RS07955	COG0420	3'-5' exonuclease activity
AVT04_RS07960	COG0419	ATPase involved in DNA repair
AVT04_RS07975	COG1442	glycosyl transferase family 8
AVT04_RS07975	COG1216	Glycosyl transferase, family 2
AVT04_RS07985	COG1280	lysine exporter protein (LysE YggA)
AVT04_RS08005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVT04_RS08035	COG4868	Belongs to the UPF0371 family
AVT04_RS08045	COG0656	L-ascorbic acid biosynthetic process
AVT04_RS08055	COG0778	Nitroreductase
AVT04_RS08060	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AVT04_RS08060	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AVT04_RS08070	COG1959	2 iron, 2 sulfur cluster binding
AVT04_RS08085	COG0531	amino acid
AVT04_RS08095	COG1482	cell wall glycoprotein biosynthetic process
AVT04_RS08100	COG1482	cell wall glycoprotein biosynthetic process
AVT04_RS08110	COG1473	amidohydrolase
AVT04_RS08120	COG0371	Dehydrogenase
AVT04_RS08130	COG0436	Aminotransferase
AVT04_RS08135	COG2079	MmgE PrpD family protein
AVT04_RS08145	COG0765	amino acid transport
AVT04_RS08150	COG1126	abc transporter atp-binding protein
AVT04_RS08165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVT04_RS08165	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVT04_RS08170	COG0534	Mate efflux family protein
AVT04_RS08180	COG2801	Transposase and inactivated derivatives
AVT04_RS08185	COG2233	PERMEase
AVT04_RS08190	COG2233	PERMEase
AVT04_RS08200	COG0745	RESPONSE REGULATOR receiver
AVT04_RS08205	COG2198	Histidine kinase
AVT04_RS08205	COG5002	protein histidine kinase activity
AVT04_RS08205	COG0784	Response regulator, receiver
AVT04_RS08210	COG1136	(ABC) transporter
AVT04_RS08215	COG0577	efflux transmembrane transporter activity
AVT04_RS08230	COG0385	Bile acid
AVT04_RS08245	COG1131	(ABC) transporter
AVT04_RS08255	COG4585	Histidine kinase
AVT04_RS08260	COG2197	response regulator
AVT04_RS08265	COG1131	(ABC) transporter
AVT04_RS08270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AVT04_RS08295	COG1760	l-serine dehydratase
AVT04_RS08300	COG1760	l-serine dehydratase
AVT04_RS08305	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AVT04_RS08315	COG2986	histidine ammonia-lyase
AVT04_RS08330	COG1125	glycine betaine transport
AVT04_RS08330	COG0517	IMP dehydrogenase activity
AVT04_RS08340	COG1268	BioY protein
AVT04_RS08345	COG1011	Hydrolase
AVT04_RS08355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVT04_RS08380	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AVT04_RS08395	COG1196	nuclear chromosome segregation
AVT04_RS08425	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AVT04_RS08425	COG1328	CTP reductase activity
AVT04_RS08430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVT04_RS08455	COG0488	(ABC) transporter
AVT04_RS08505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVT04_RS08510	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVT04_RS08515	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVT04_RS08520	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AVT04_RS08525	COG0372	Belongs to the citrate synthase family
AVT04_RS08550	COG0513	Belongs to the DEAD box helicase family
AVT04_RS08560	COG0488	(ABC) transporter
AVT04_RS08575	COG0392	lysyltransferase activity
AVT04_RS08575	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AVT04_RS08580	COG3442	glutamine amidotransferase
AVT04_RS08585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AVT04_RS08610	COG2384	SAM-dependent methyltransferase
AVT04_RS08625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVT04_RS08630	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AVT04_RS08640	COG1088	dTDP-glucose 4,6-dehydratase activity
AVT04_RS08660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVT04_RS08670	COG0647	UMP catabolic process
AVT04_RS08695	COG0772	Belongs to the SEDS family
AVT04_RS08700	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AVT04_RS08715	COG0300	oxidoreductase activity
AVT04_RS08720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AVT04_RS08720	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AVT04_RS08740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AVT04_RS08765	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AVT04_RS08770	COG1438	arginine binding
AVT04_RS08775	COG0497	DNA recombination
AVT04_RS08780	COG1307	EDD domain protein, DegV family
AVT04_RS08785	COG2755	lipolytic protein G-D-S-L family
AVT04_RS08795	COG0776	regulation of translation
AVT04_RS08805	COG0167	dihydroorotate dehydrogenase activity
AVT04_RS08865	COG0469	pyruvate kinase activity
AVT04_RS08935	COG0716	FMN binding
AVT04_RS08940	COG0038	chloride channel
AVT04_RS08950	COG0038	chloride channel
AVT04_RS08955	COG0335	large ribosomal subunit rRNA binding
AVT04_RS08975	COG1956	GAF domain-containing protein
AVT04_RS08980	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AVT04_RS08990	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AVT04_RS08990	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AVT04_RS09005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AVT04_RS09030	COG0765	amino acid transport
AVT04_RS09035	COG0765	amino acid transport
AVT04_RS09040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVT04_RS09045	COG1126	abc transporter atp-binding protein
AVT04_RS09050	COG0745	RESPONSE REGULATOR receiver
AVT04_RS09055	COG5002	protein histidine kinase activity
AVT04_RS09060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AVT04_RS09070	COG2348	transferase activity, transferring amino-acyl groups
AVT04_RS09105	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AVT04_RS09110	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AVT04_RS09115	COG2884	Cell division ATP-binding protein ftsE
AVT04_RS09120	COG2177	Part of the ABC transporter FtsEX involved in
AVT04_RS09125	COG1051	belongs to the nudix hydrolase family
AVT04_RS09130	COG0628	permease
AVT04_RS09140	COG0681	Belongs to the peptidase S26 family
AVT04_RS09165	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AVT04_RS09205	COG1573	uracil-dna glycosylase
AVT04_RS09220	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AVT04_RS09230	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AVT04_RS09250	COG1316	TRANSCRIPTIONal
AVT04_RS09270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AVT04_RS09290	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AVT04_RS09295	COG1216	Glycosyl transferase, family 2
AVT04_RS09295	COG1442	glycosyl transferase family 8
AVT04_RS09310	COG5039	Polysaccharide pyruvyl transferase
AVT04_RS09350	COG0628	permease
AVT04_RS09365	COG2723	6-phospho-beta-galactosidase activity
AVT04_RS09390	COG4667	esterase of the alpha-beta hydrolase superfamily
AVT04_RS09405	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AVT04_RS09435	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AVT04_RS09440	COG0022	dehydrogenase e1 component
AVT04_RS09440	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVT04_RS09445	COG0508	dehydrogenase complex catalyzes the overall conversion of