locus-tag	class	description
SMQ301_RS00005	COG1475	DNA binding
SMQ301_RS00015	COG0592	DNA-directed DNA polymerase activity
SMQ301_RS00030	COG0012	GTP binding
SMQ301_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SMQ301_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SMQ301_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SMQ301_RS00095	COG2801	Transposase and inactivated derivatives
SMQ301_RS00215	COG3942	CHAP domain
SMQ301_RS00235	COG0436	Aminotransferase
SMQ301_RS00250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SMQ301_RS00260	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SMQ301_RS00275	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SMQ301_RS00295	COG2801	Transposase and inactivated derivatives
SMQ301_RS00300	COG3942	CHAP domain
SMQ301_RS00300	COG1388	LysM domain
SMQ301_RS00305	COG0151	Belongs to the GarS family
SMQ301_RS00310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SMQ301_RS00330	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SMQ301_RS00345	COG4550	Control of competence regulator ComK, YlbF/YmcA
SMQ301_RS00385	COG2818	Glycosylase
SMQ301_RS00400	COG1393	Belongs to the ArsC family
SMQ301_RS00490	COG2309	aminopeptidase activity
SMQ301_RS00505	COG0431	NADPH-dependent FMN reductase
SMQ301_RS00510	COG2801	Transposase and inactivated derivatives
SMQ301_RS00545	COG4463	regulation of RNA biosynthetic process
SMQ301_RS00550	COG0542	response to heat
SMQ301_RS00565	COG2801	Transposase and inactivated derivatives
SMQ301_RS00570	COG1686	Belongs to the peptidase S11 family
SMQ301_RS00585	COG1045	serine acetyltransferase
SMQ301_RS00595	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SMQ301_RS00610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SMQ301_RS00635	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SMQ301_RS00695	COG0601	transmembrane transport
SMQ301_RS00700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SMQ301_RS00705	COG4172	Belongs to the ABC transporter superfamily
SMQ301_RS00755	COG3830	Belongs to the UPF0237 family
SMQ301_RS00765	COG0588	phosphoglycerate mutase activity
SMQ301_RS00770	COG1876	peptidase activity
SMQ301_RS00805	COG0351	phosphomethylpyrimidine kinase
SMQ301_RS00915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SMQ301_RS00930	COG0668	transmembrane transport
SMQ301_RS00945	COG0504	CTP synthase activity
SMQ301_RS00955	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SMQ301_RS00965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SMQ301_RS00970	COG0737	Belongs to the 5'-nucleotidase family
SMQ301_RS01005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SMQ301_RS01035	COG1126	abc transporter atp-binding protein
SMQ301_RS01040	COG0765	amino acid transport
SMQ301_RS01050	COG4862	establishment of competence for transformation
SMQ301_RS01055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SMQ301_RS01065	COG0719	Fe-S assembly protein
SMQ301_RS01070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SMQ301_RS01080	COG0719	Fe-S assembly protein
SMQ301_RS01090	COG0601	transmembrane transport
SMQ301_RS01115	COG0444	Belongs to the ABC transporter superfamily
SMQ301_RS01120	COG0444	Belongs to the ABC transporter superfamily
SMQ301_RS01125	COG4608	Belongs to the ABC transporter superfamily
SMQ301_RS01140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SMQ301_RS01155	COG1121	(ABC) transporter
SMQ301_RS01160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SMQ301_RS01170	COG1263	PTS System
SMQ301_RS01170	COG2190	(PTS) system
SMQ301_RS01170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SMQ301_RS01175	COG1263	PTS System
SMQ301_RS01175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SMQ301_RS01175	COG2190	(PTS) system
SMQ301_RS01180	COG2190	(PTS) system
SMQ301_RS01180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SMQ301_RS01180	COG1263	PTS System
SMQ301_RS01185	COG2190	(PTS) system
SMQ301_RS01185	COG1263	PTS System
SMQ301_RS01185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SMQ301_RS01215	COG4589	Belongs to the CDS family
SMQ301_RS01230	COG4120	Belongs to the binding-protein-dependent transport system permease family
SMQ301_RS01235	COG1116	anion transmembrane transporter activity
SMQ301_RS01235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SMQ301_RS01280	COG0564	pseudouridine synthase activity
SMQ301_RS01285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SMQ301_RS01340	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SMQ301_RS01355	COG3579	cysteine-type endopeptidase activity
SMQ301_RS01360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SMQ301_RS01380	COG0116	Belongs to the methyltransferase superfamily
SMQ301_RS01390	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SMQ301_RS01410	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SMQ301_RS01425	COG2801	Transposase and inactivated derivatives
SMQ301_RS01435	COG1254	Belongs to the acylphosphatase family
SMQ301_RS01440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SMQ301_RS01485	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SMQ301_RS01515	COG1187	pseudouridine synthase activity
SMQ301_RS01525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SMQ301_RS01530	COG0569	domain protein
SMQ301_RS01540	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SMQ301_RS01545	COG0671	phosphoesterase, PA-phosphatase related
SMQ301_RS01565	COG2274	protein secretion by the type I secretion system
SMQ301_RS01570	COG2274	protein secretion by the type I secretion system
SMQ301_RS01625	COG0310	cobalt ion transport
SMQ301_RS01635	COG1122	ATPase activity
SMQ301_RS01640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SMQ301_RS01645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SMQ301_RS01665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SMQ301_RS01670	COG1464	Belongs to the NlpA lipoprotein family
SMQ301_RS01705	COG1122	ATPase activity
SMQ301_RS01715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SMQ301_RS01725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SMQ301_RS01740	COG0745	RESPONSE REGULATOR receiver
SMQ301_RS01745	COG5002	protein histidine kinase activity
SMQ301_RS01760	COG1484	DNA-dependent DNA replication
SMQ301_RS01775	COG2801	Transposase and inactivated derivatives
SMQ301_RS01795	COG3328	transposase activity
SMQ301_RS01810	COG3716	PTS system mannose fructose sorbose family IID component
SMQ301_RS01815	COG3715	PTS system
SMQ301_RS01825	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SMQ301_RS01830	COG0561	phosphatase activity
SMQ301_RS01835	COG2252	PERMEase
SMQ301_RS01840	COG0802	atpase or kinase
SMQ301_RS01845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SMQ301_RS01850	COG1316	TRANSCRIPTIONal
SMQ301_RS01860	COG0195	Participates in both transcription termination and antitermination
SMQ301_RS01865	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SMQ301_RS01885	COG1611	Belongs to the LOG family
SMQ301_RS01905	COG2244	polysaccharide biosynthetic process
SMQ301_RS01910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SMQ301_RS01915	COG0626	cystathionine gamma-synthase activity
SMQ301_RS01920	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SMQ301_RS01950	COG4471	UPF0298 protein
SMQ301_RS01960	COG0559	Belongs to the binding-protein-dependent transport system permease family
SMQ301_RS01980	COG0517	IMP dehydrogenase activity
SMQ301_RS01995	COG1739	Uncharacterized protein family UPF0029
SMQ301_RS02000	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SMQ301_RS02005	COG1040	competence protein
SMQ301_RS02095	COG0527	aspartate kinase activity
SMQ301_RS02100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SMQ301_RS02105	COG1024	Enoyl-CoA hydratase
SMQ301_RS02110	COG1846	Transcriptional regulator
SMQ301_RS02130	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SMQ301_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
SMQ301_RS02140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SMQ301_RS02155	COG0439	Biotin carboxylase
SMQ301_RS02190	COG1349	DNA-binding transcription factor activity
SMQ301_RS02195	COG1105	Belongs to the carbohydrate kinase PfkB family
SMQ301_RS02205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SMQ301_RS02210	COG0285	dihydrofolate synthase activity
SMQ301_RS02220	COG1104	cysteine desulfurase activity
SMQ301_RS02285	COG0488	(ABC) transporter
SMQ301_RS02310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SMQ301_RS02315	COG0242	peptide deformylase activity
SMQ301_RS02375	COG1702	phosphate starvation-inducible protein PhoH
SMQ301_RS02395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SMQ301_RS02395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SMQ301_RS02420	COG4122	O-methyltransferase activity
SMQ301_RS02425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SMQ301_RS02450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SMQ301_RS02455	COG0436	Aminotransferase
SMQ301_RS02470	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SMQ301_RS02475	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SMQ301_RS02480	COG0726	polysaccharide deacetylase
SMQ301_RS02495	COG2962	Rard protein
SMQ301_RS02530	COG0356	it plays a direct role in the translocation of protons across the membrane
SMQ301_RS02565	COG0772	Belongs to the SEDS family
SMQ301_RS02585	COG0470	DNA polymerase III
SMQ301_RS02590	COG1774	PSP1 C-terminal conserved region
SMQ301_RS02595	COG4467	Involved in initiation control of chromosome replication
SMQ301_RS02605	COG0004	ammonium transporteR
SMQ301_RS02610	COG0347	Belongs to the P(II) protein family
SMQ301_RS02615	COG1705	Flagellar rod assembly protein muramidase FlgJ
SMQ301_RS02615	COG1388	LysM domain
SMQ301_RS02670	COG1113	amino acid transport
SMQ301_RS02680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SMQ301_RS02680	COG1263	PTS System
SMQ301_RS02680	COG2190	(PTS) system
SMQ301_RS02695	COG2801	Transposase and inactivated derivatives
SMQ301_RS02725	COG0583	DNA-binding transcription factor activity
SMQ301_RS02735	COG0564	pseudouridine synthase activity
SMQ301_RS02755	COG0505	Belongs to the CarA family
SMQ301_RS02805	COG0577	efflux transmembrane transporter activity
SMQ301_RS02855	COG3279	Response regulator of the LytR AlgR family
SMQ301_RS02865	COG1131	(ABC) transporter
SMQ301_RS02900	COG1187	pseudouridine synthase activity
SMQ301_RS02905	COG1473	amidohydrolase
SMQ301_RS02910	COG0686	Belongs to the AlaDH PNT family
SMQ301_RS02915	COG0686	Belongs to the AlaDH PNT family
SMQ301_RS02920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SMQ301_RS02985	COG0438	transferase activity, transferring glycosyl groups
SMQ301_RS03015	COG1272	protein, Hemolysin III
SMQ301_RS03030	COG3425	synthase
SMQ301_RS03040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SMQ301_RS03060	COG0833	amino acid
SMQ301_RS03065	COG2040	homocysteine
SMQ301_RS03085	COG0187	DNA topoisomerase II activity
SMQ301_RS03095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SMQ301_RS03115	COG0539	negative regulation of cytoplasmic translation
SMQ301_RS03170	COG0494	nUDIX hydrolase
SMQ301_RS03175	COG0542	response to heat
SMQ301_RS03180	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SMQ301_RS03185	COG4703	Protein of unknown function (DUF1797)
SMQ301_RS03190	COG0765	amino acid transport
SMQ301_RS03240	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SMQ301_RS03245	COG0768	penicillin binding
SMQ301_RS03260	COG3711	transcriptional antiterminator
SMQ301_RS03270	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SMQ301_RS03275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SMQ301_RS03280	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SMQ301_RS03285	COG0237	dephospho-CoA kinase activity
SMQ301_RS03300	COG0557	exoribonuclease II activity
SMQ301_RS03315	COG1185	polyribonucleotide nucleotidyltransferase activity
SMQ301_RS03320	COG0006	proline dipeptidase activity
SMQ301_RS03325	COG1609	Transcriptional regulator
SMQ301_RS03360	COG1368	sulfuric ester hydrolase activity
SMQ301_RS03365	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SMQ301_RS03390	COG0287	Prephenate dehydrogenase
SMQ301_RS03415	COG0077	Prephenate dehydratase
SMQ301_RS03475	COG1518	maintenance of DNA repeat elements
SMQ301_RS03480	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SMQ301_RS03490	COG3689	TIGRFAM TIGR03943 family protein
SMQ301_RS03495	COG0701	Predicted permease
SMQ301_RS03500	COG2183	response to ionizing radiation
SMQ301_RS03520	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SMQ301_RS03545	COG0826	peptidase U32
SMQ301_RS03550	COG1268	BioY protein
SMQ301_RS03560	COG4443	Transcriptional Coactivator p15 (PC4)
SMQ301_RS03565	COG1914	H( )-stimulated, divalent metal cation uptake system
SMQ301_RS03590	COG1388	LysM domain
SMQ301_RS03590	COG1705	Flagellar rod assembly protein muramidase FlgJ
SMQ301_RS03610	COG0406	alpha-ribazole phosphatase activity
SMQ301_RS03615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SMQ301_RS03645	COG4221	oxidoreductase activity
SMQ301_RS03650	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SMQ301_RS03690	COG3620	sequence-specific DNA binding
SMQ301_RS03710	COG1704	LemA family
SMQ301_RS03740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SMQ301_RS03755	COG0783	Belongs to the Dps family
SMQ301_RS03760	COG0735	belongs to the Fur family
SMQ301_RS03765	COG4483	Protein conserved in bacteria
SMQ301_RS03770	COG1940	carbohydrate kinase activity
SMQ301_RS03775	COG1217	gtp-binding protein TYPA
SMQ301_RS03805	COG0849	cell division
SMQ301_RS03815	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SMQ301_RS03835	COG3599	regulation of cell shape
SMQ301_RS03870	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SMQ301_RS03875	COG0625	glutathione transferase activity
SMQ301_RS03880	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SMQ301_RS03885	COG1435	thymidine kinase activity
SMQ301_RS03895	COG2890	protein-(glutamine-N5) methyltransferase activity
SMQ301_RS03925	COG1132	(ABC) transporter
SMQ301_RS03940	COG1696	Membrane protein involved in D-alanine export
SMQ301_RS03950	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SMQ301_RS03960	COG2801	Transposase and inactivated derivatives
SMQ301_RS03965	COG2801	Transposase and inactivated derivatives
SMQ301_RS03985	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SMQ301_RS03990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SMQ301_RS04075	COG1396	sequence-specific DNA binding
SMQ301_RS04080	COG0582	viral genome integration into host DNA
SMQ301_RS04100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SMQ301_RS04105	COG4684	Psort location CytoplasmicMembrane, score
SMQ301_RS04110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SMQ301_RS04135	COG5002	protein histidine kinase activity
SMQ301_RS04150	COG2801	Transposase and inactivated derivatives
SMQ301_RS04170	COG0038	chloride channel
SMQ301_RS04190	COG2801	Transposase and inactivated derivatives
SMQ301_RS04210	COG2813	Specifically methylates the guanine in position
SMQ301_RS04230	COG0295	cytidine deaminase activity
SMQ301_RS04235	COG1744	ABC transporter substrate-binding protein PnrA-like
SMQ301_RS04240	COG3845	ABC transporter
SMQ301_RS04245	COG4603	Belongs to the binding-protein-dependent transport system permease family
SMQ301_RS04250	COG1079	Belongs to the binding-protein-dependent transport system permease family
SMQ301_RS04260	COG1199	ATP-dependent helicase activity
SMQ301_RS04260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SMQ301_RS04270	COG0436	Aminotransferase
SMQ301_RS04305	COG0251	oxidation-reduction process
SMQ301_RS04315	COG0720	synthase
SMQ301_RS04365	COG1278	Cold shock
SMQ301_RS04375	COG3328	transposase activity
SMQ301_RS04380	COG2217	Heavy metal translocating P-type atpase
SMQ301_RS04385	COG3328	transposase activity
SMQ301_RS04395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SMQ301_RS04400	COG0626	cystathionine gamma-synthase activity
SMQ301_RS04405	COG1045	serine acetyltransferase
SMQ301_RS04410	COG3328	transposase activity
SMQ301_RS04415	COG3443	Belongs to the bacterial solute-binding protein 9 family
SMQ301_RS04415	COG0803	Belongs to the bacterial solute-binding protein 9 family
SMQ301_RS04435	COG1705	Flagellar rod assembly protein muramidase FlgJ
SMQ301_RS04435	COG3942	CHAP domain
SMQ301_RS04450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SMQ301_RS04455	COG2824	Alkylphosphonate utilization operon protein PhnA
SMQ301_RS04460	COG0765	amino acid transport
SMQ301_RS04465	COG1126	abc transporter atp-binding protein
SMQ301_RS04470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SMQ301_RS04495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SMQ301_RS04495	COG0519	Catalyzes the synthesis of GMP from XMP
SMQ301_RS04500	COG2188	Transcriptional regulator
SMQ301_RS04510	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SMQ301_RS04520	COG1827	regulation of RNA biosynthetic process
SMQ301_RS04530	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SMQ301_RS04540	COG1940	carbohydrate kinase activity
SMQ301_RS04545	COG0758	DNA mediated transformation
SMQ301_RS04550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SMQ301_RS04600	COG1396	sequence-specific DNA binding
SMQ301_RS04610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SMQ301_RS04615	COG0010	Belongs to the arginase family
SMQ301_RS04625	COG0028	Belongs to the TPP enzyme family
SMQ301_RS04630	COG3527	Alpha-acetolactate decarboxylase
SMQ301_RS04665	COG1230	cation diffusion facilitator family transporter
SMQ301_RS04675	COG1063	alcohol dehydrogenase
SMQ301_RS04700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SMQ301_RS04720	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SMQ301_RS04750	COG0047	phosphoribosylformylglycinamidine synthase activity
SMQ301_RS04765	COG0167	dihydroorotate dehydrogenase activity
SMQ301_RS04770	COG1518	maintenance of DNA repeat elements
SMQ301_RS04770	COG1468	defense response to virus
SMQ301_RS04775	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SMQ301_RS04795	COG1337	RAMP superfamily
SMQ301_RS04800	COG1567	CRISPR-associated RAMP protein, Csm4 family
SMQ301_RS04830	COG3104	oligopeptide transport
SMQ301_RS04845	COG0737	Belongs to the 5'-nucleotidase family
SMQ301_RS04870	COG1115	amino acid carrier protein
SMQ301_RS04880	COG2873	o-acetylhomoserine
SMQ301_RS04910	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SMQ301_RS04915	COG0196	riboflavin kinase activity
SMQ301_RS04920	COG1393	Belongs to the ArsC family
SMQ301_RS04930	COG0483	inositol monophosphate 1-phosphatase activity
SMQ301_RS04935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SMQ301_RS04935	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SMQ301_RS04945	COG0573	inorganic phosphate transmembrane transporter activity
SMQ301_RS04950	COG0581	inorganic phosphate transmembrane transporter activity
SMQ301_RS04965	COG0704	Plays a role in the regulation of phosphate uptake
SMQ301_RS04980	COG0095	Lipoate-protein ligase
SMQ301_RS04995	COG0058	SHG alpha-glucan phosphorylase activity
SMQ301_RS05000	COG1640	4-alpha-glucanotransferase
SMQ301_RS05015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SMQ301_RS05020	COG0805	protein transport
SMQ301_RS05025	COG0672	)-iron permease
SMQ301_RS05030	COG2837	iron assimilation
SMQ301_RS05035	COG2822	iron ion transport
SMQ301_RS05040	COG4607	ABC-type enterochelin transport system periplasmic component
SMQ301_RS05045	COG4604	ABC transporter, ATP-binding protein
SMQ301_RS05050	COG4605	iron ion homeostasis
SMQ301_RS05055	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SMQ301_RS05065	COG1523	belongs to the glycosyl hydrolase 13 family
SMQ301_RS05075	COG1523	belongs to the glycosyl hydrolase 13 family
SMQ301_RS05105	COG0508	dehydrogenase complex catalyzes the overall conversion of
SMQ301_RS05110	COG0022	dehydrogenase e1 component
SMQ301_RS05110	COG0508	dehydrogenase complex catalyzes the overall conversion of
SMQ301_RS05115	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SMQ301_RS05145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SMQ301_RS05150	COG4667	esterase of the alpha-beta hydrolase superfamily
SMQ301_RS05190	COG0628	permease
SMQ301_RS05225	COG2244	polysaccharide biosynthetic process
SMQ301_RS05230	COG1216	Glycosyl transferase, family 2
SMQ301_RS05230	COG1442	glycosyl transferase family 8
SMQ301_RS05235	COG0489	protein tyrosine kinase activity
SMQ301_RS05270	COG1216	Glycosyl transferase, family 2
SMQ301_RS05270	COG1442	glycosyl transferase family 8
SMQ301_RS05285	COG0297	glycogen (starch) synthase activity
SMQ301_RS05300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SMQ301_RS05320	COG1316	TRANSCRIPTIONal
SMQ301_RS05340	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SMQ301_RS05345	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SMQ301_RS05365	COG1573	uracil-dna glycosylase
SMQ301_RS05425	COG0681	Belongs to the peptidase S26 family
SMQ301_RS05435	COG0628	permease
SMQ301_RS05440	COG1051	belongs to the nudix hydrolase family
SMQ301_RS05445	COG2177	Part of the ABC transporter FtsEX involved in
SMQ301_RS05450	COG2884	Cell division ATP-binding protein ftsE
SMQ301_RS05455	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SMQ301_RS05460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SMQ301_RS05495	COG2348	transferase activity, transferring amino-acyl groups
SMQ301_RS05505	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SMQ301_RS05510	COG5002	protein histidine kinase activity
SMQ301_RS05515	COG0745	RESPONSE REGULATOR receiver
SMQ301_RS05520	COG1126	abc transporter atp-binding protein
SMQ301_RS05525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SMQ301_RS05530	COG0765	amino acid transport
SMQ301_RS05535	COG0765	amino acid transport
SMQ301_RS05560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SMQ301_RS05600	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SMQ301_RS05605	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SMQ301_RS05605	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SMQ301_RS05615	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SMQ301_RS05620	COG1956	GAF domain-containing protein
SMQ301_RS05625	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SMQ301_RS05655	COG0335	large ribosomal subunit rRNA binding
SMQ301_RS05660	COG0038	chloride channel
SMQ301_RS05670	COG0038	chloride channel
SMQ301_RS05675	COG0716	FMN binding
SMQ301_RS05750	COG0469	pyruvate kinase activity
SMQ301_RS05800	COG0167	dihydroorotate dehydrogenase activity
SMQ301_RS05810	COG0776	regulation of translation
SMQ301_RS05820	COG2755	lipolytic protein G-D-S-L family
SMQ301_RS05825	COG1307	EDD domain protein, DegV family
SMQ301_RS05830	COG0497	DNA recombination
SMQ301_RS05835	COG1438	arginine binding
SMQ301_RS05840	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SMQ301_RS05865	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SMQ301_RS05885	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SMQ301_RS05885	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SMQ301_RS05890	COG0300	oxidoreductase activity
SMQ301_RS05905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SMQ301_RS05915	COG0772	Belongs to the SEDS family
SMQ301_RS05930	COG0107	imidazoleglycerol-phosphate synthase activity
SMQ301_RS05940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SMQ301_RS05950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SMQ301_RS06005	COG0647	UMP catabolic process
SMQ301_RS06015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SMQ301_RS06035	COG1088	dTDP-glucose 4,6-dehydratase activity
SMQ301_RS06045	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SMQ301_RS06050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SMQ301_RS06065	COG2384	SAM-dependent methyltransferase
SMQ301_RS06090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SMQ301_RS06095	COG3442	glutamine amidotransferase
SMQ301_RS06100	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SMQ301_RS06100	COG0392	lysyltransferase activity
SMQ301_RS06115	COG0488	(ABC) transporter
SMQ301_RS06125	COG0513	Belongs to the DEAD box helicase family
SMQ301_RS06155	COG0372	Belongs to the citrate synthase family
SMQ301_RS06160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SMQ301_RS06165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SMQ301_RS06170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SMQ301_RS06175	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SMQ301_RS06200	COG0346	lactoylglutathione lyase activity
SMQ301_RS06205	COG3764	Sortase (surface protein transpeptidase)
SMQ301_RS06225	COG0488	(ABC) transporter
SMQ301_RS06255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SMQ301_RS06260	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SMQ301_RS06260	COG1328	CTP reductase activity
SMQ301_RS06285	COG1196	nuclear chromosome segregation
SMQ301_RS06300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SMQ301_RS06310	COG1247	-acetyltransferase
SMQ301_RS06325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SMQ301_RS06335	COG1011	Hydrolase
SMQ301_RS06340	COG1760	l-serine dehydratase
SMQ301_RS06345	COG1760	l-serine dehydratase
SMQ301_RS06370	COG2197	response regulator
SMQ301_RS06375	COG4585	Histidine kinase
SMQ301_RS06385	COG1131	(ABC) transporter
SMQ301_RS06435	COG1131	(ABC) transporter
SMQ301_RS06455	COG0577	efflux transmembrane transporter activity
SMQ301_RS06460	COG1136	(ABC) transporter
SMQ301_RS06465	COG0784	Response regulator, receiver
SMQ301_RS06465	COG5002	protein histidine kinase activity
SMQ301_RS06465	COG2198	Histidine kinase
SMQ301_RS06470	COG0745	RESPONSE REGULATOR receiver
SMQ301_RS06480	COG2233	PERMEase
SMQ301_RS06485	COG2233	PERMEase
SMQ301_RS06490	COG0534	Mate efflux family protein
SMQ301_RS06495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SMQ301_RS06495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SMQ301_RS06505	COG1482	cell wall glycoprotein biosynthetic process
SMQ301_RS06510	COG1482	cell wall glycoprotein biosynthetic process
SMQ301_RS06520	COG0531	amino acid
SMQ301_RS06530	COG2514	catechol 2,3-dioxygenase activity
SMQ301_RS06535	COG1959	2 iron, 2 sulfur cluster binding
SMQ301_RS06545	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SMQ301_RS06545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SMQ301_RS06550	COG0778	Nitroreductase
SMQ301_RS06560	COG0656	L-ascorbic acid biosynthetic process
SMQ301_RS06565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SMQ301_RS06580	COG0745	RESPONSE REGULATOR receiver
SMQ301_RS06605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SMQ301_RS06620	COG1280	lysine exporter protein (LysE YggA)
SMQ301_RS06630	COG1442	glycosyl transferase family 8
SMQ301_RS06630	COG1216	Glycosyl transferase, family 2
SMQ301_RS06635	COG0577	efflux transmembrane transporter activity
SMQ301_RS06680	COG1396	sequence-specific DNA binding
SMQ301_RS06685	COG2801	Transposase and inactivated derivatives
SMQ301_RS06700	COG0419	ATPase involved in DNA repair
SMQ301_RS06705	COG0420	3'-5' exonuclease activity
SMQ301_RS06710	COG3250	beta-galactosidase activity
SMQ301_RS06715	COG2190	(PTS) system
SMQ301_RS06715	COG2211	Major facilitator Superfamily
SMQ301_RS06720	COG2017	converts alpha-aldose to the beta-anomer
SMQ301_RS06725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SMQ301_RS06740	COG1609	Transcriptional regulator
SMQ301_RS06755	COG3064	Membrane
SMQ301_RS06760	COG0488	(ABC) transporter
SMQ301_RS06815	COG2197	response regulator
SMQ301_RS06820	COG4585	Histidine kinase
SMQ301_RS06830	COG2815	serine threonine protein kinase
SMQ301_RS06830	COG0515	serine threonine protein kinase
SMQ301_RS06840	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SMQ301_RS06840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SMQ301_RS06850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SMQ301_RS06865	COG0552	protein localization to endoplasmic reticulum
SMQ301_RS06870	COG0561	phosphatase activity
SMQ301_RS06875	COG0561	phosphatase activity
SMQ301_RS06880	COG1725	Transcriptional regulator
SMQ301_RS06885	COG1131	(ABC) transporter
SMQ301_RS06895	COG4608	Belongs to the ABC transporter superfamily
SMQ301_RS06900	COG0444	Belongs to the ABC transporter superfamily
SMQ301_RS06905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SMQ301_RS06910	COG0601	transmembrane transport
SMQ301_RS06915	COG4166	transmembrane transport
SMQ301_RS06925	COG4166	transmembrane transport
SMQ301_RS06935	COG2801	Transposase and inactivated derivatives
SMQ301_RS06940	COG4608	Belongs to the ABC transporter superfamily
SMQ301_RS06945	COG4608	Belongs to the ABC transporter superfamily
SMQ301_RS06950	COG0084	hydrolase, TatD family'
SMQ301_RS06955	COG2223	nitrite transmembrane transporter activity
SMQ301_RS06960	COG2801	Transposase and inactivated derivatives
SMQ301_RS06970	COG0280	phosphate acetyltransferase
SMQ301_RS06975	COG0564	pseudouridine synthase activity
SMQ301_RS06985	COG2357	RelA SpoT domain protein
SMQ301_RS06990	COG4116	CYTH
SMQ301_RS07000	COG1104	cysteine desulfurase activity
SMQ301_RS07015	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SMQ301_RS07020	COG2003	Belongs to the UPF0758 family
SMQ301_RS07050	COG1215	transferase activity, transferring glycosyl groups
SMQ301_RS07070	COG0463	Glycosyl transferase, family 2
SMQ301_RS07075	COG1216	Glycosyl transferase, family 2
SMQ301_RS07080	COG1216	Glycosyl transferase, family 2
SMQ301_RS07090	COG1091	dTDP-4-dehydrorhamnose reductase activity
SMQ301_RS07100	COG0463	Glycosyl transferase, family 2
SMQ301_RS07105	COG2151	metal-sulfur cluster biosynthetic enzyme
SMQ301_RS07110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SMQ301_RS07115	COG0358	DNA primase activity
SMQ301_RS07120	COG1970	mechanosensitive ion channel activity
SMQ301_RS07130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SMQ301_RS07135	COG0436	Aminotransferase
SMQ301_RS07140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SMQ301_RS07145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SMQ301_RS07150	COG1051	belongs to the nudix hydrolase family
SMQ301_RS07175	COG0765	amino acid transport
SMQ301_RS07180	COG1126	abc transporter atp-binding protein
SMQ301_RS07195	COG1187	pseudouridine synthase activity
SMQ301_RS07235	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SMQ301_RS07240	COG1518	maintenance of DNA repeat elements
SMQ301_RS07250	COG0560	Phosphoserine phosphatase
SMQ301_RS07260	COG0187	DNA topoisomerase II activity
SMQ301_RS07270	COG1346	cytolysis
SMQ301_RS07275	COG1380	Effector of murein hydrolase LrgA
SMQ301_RS07285	COG1393	Belongs to the ArsC family
SMQ301_RS07295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SMQ301_RS07335	COG1177	transmembrane transport
SMQ301_RS07340	COG1176	ABC-type spermidine putrescine transport system, permease component I
SMQ301_RS07380	COG0531	amino acid
SMQ301_RS07385	COG0285	dihydrofolate synthase activity
SMQ301_RS07390	COG1837	Belongs to the UPF0109 family
SMQ301_RS07400	COG3615	Tellurite resistance protein tehB
SMQ301_RS07400	COG0500	methyltransferase
SMQ301_RS07410	COG0708	Exodeoxyribonuclease III
SMQ301_RS07425	COG1597	lipid kinase activity
SMQ301_RS07435	COG4708	membrane
SMQ301_RS07445	COG0024	Methionine aminopeptidase
SMQ301_RS07450	COG4109	DRTGG domain
SMQ301_RS07460	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SMQ301_RS07465	COG0658	competence protein
SMQ301_RS07465	COG2333	competence protein COMEC
SMQ301_RS07470	COG1555	photosystem II stabilization
SMQ301_RS07470	COG1596	polysaccharide export
SMQ301_RS07475	COG0204	Acyl-transferase
SMQ301_RS07480	COG0726	polysaccharide deacetylase
SMQ301_RS07485	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SMQ301_RS07495	COG0513	Belongs to the DEAD box helicase family
SMQ301_RS07515	COG1396	sequence-specific DNA binding
SMQ301_RS07520	COG2211	Major facilitator Superfamily
SMQ301_RS07535	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SMQ301_RS07550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SMQ301_RS07555	COG1126	abc transporter atp-binding protein
SMQ301_RS07560	COG0765	amino acid transport
SMQ301_RS07565	COG0765	amino acid transport
SMQ301_RS07585	COG2217	Heavy metal translocating P-type atpase
SMQ301_RS07605	COG0135	phosphoribosylanthranilate isomerase activity
SMQ301_RS07620	COG0512	Glutamine amidotransferase of anthranilate synthase
SMQ301_RS07625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SMQ301_RS07630	COG1605	Chorismate mutase
SMQ301_RS07630	COG0287	Prephenate dehydrogenase
SMQ301_RS07645	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SMQ301_RS07670	COG2176	DNA-directed DNA polymerase activity
SMQ301_RS07680	COG2151	metal-sulfur cluster biosynthetic enzyme
SMQ301_RS07690	COG2081	HI0933 family
SMQ301_RS07715	COG1131	(ABC) transporter
SMQ301_RS07720	COG0537	adenosine 5'-monophosphoramidase activity
SMQ301_RS07750	COG2226	methyltransferase
SMQ301_RS07755	COG0799	negative regulation of ribosome biogenesis
SMQ301_RS07760	COG1713	HD superfamily hydrolase involved in NAD metabolism
SMQ301_RS07765	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SMQ301_RS07770	COG1534	Rna-binding protein
SMQ301_RS07775	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SMQ301_RS07780	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SMQ301_RS07815	COG2723	6-phospho-beta-galactosidase activity
SMQ301_RS07830	COG1335	isochorismatase
SMQ301_RS07840	COG0436	Aminotransferase
SMQ301_RS07845	COG0589	response to stress
SMQ301_RS07860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SMQ301_RS07865	COG1253	flavin adenine dinucleotide binding
SMQ301_RS07870	COG1119	ATPase activity
SMQ301_RS07875	COG0025	NhaP-type Na H and K H
SMQ301_RS07885	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SMQ301_RS07890	COG1242	4 iron, 4 sulfur cluster binding
SMQ301_RS07895	COG3480	Lon protease (S16) C-terminal proteolytic domain
SMQ301_RS07900	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SMQ301_RS07905	COG0742	ribosomal rna small subunit methyltransferase
SMQ301_RS07910	COG0492	ferredoxin-NADP+ reductase activity
SMQ301_RS07920	COG1126	abc transporter atp-binding protein
SMQ301_RS07930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SMQ301_RS07945	COG1882	Formate acetyltransferase
SMQ301_RS07975	COG0390	transport system, permease component
SMQ301_RS07980	COG4619	ABC transporter
SMQ301_RS07985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SMQ301_RS08000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SMQ301_RS08075	COG3290	protein histidine kinase activity
SMQ301_RS08085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SMQ301_RS08090	COG2274	protein secretion by the type I secretion system
SMQ301_RS08095	COG1132	(ABC) transporter
SMQ301_RS08100	COG1132	(ABC) transporter
SMQ301_RS08120	COG4470	Protein conserved in bacteria
SMQ301_RS08125	COG0737	Belongs to the 5'-nucleotidase family
SMQ301_RS08130	COG0513	Belongs to the DEAD box helicase family
SMQ301_RS08140	COG0768	penicillin binding
SMQ301_RS08175	COG3152	Membrane
SMQ301_RS08195	COG4152	abc transporter atp-binding protein
SMQ301_RS08205	COG1811	Na channel or pump
SMQ301_RS08245	COG0561	phosphatase activity
SMQ301_RS08250	COG0252	asparaginase activity
SMQ301_RS08270	COG1132	(ABC) transporter
SMQ301_RS08275	COG3655	Transcriptional regulator
SMQ301_RS08300	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SMQ301_RS08315	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SMQ301_RS08320	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SMQ301_RS08335	COG1482	cell wall glycoprotein biosynthetic process
SMQ301_RS08340	COG1940	carbohydrate kinase activity
SMQ301_RS08345	COG2190	(PTS) system
SMQ301_RS08345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SMQ301_RS08345	COG1263	PTS System
SMQ301_RS08350	COG1621	beta-fructofuranosidase activity
SMQ301_RS08355	COG1609	Transcriptional regulator
SMQ301_RS08375	COG2131	deaminase
SMQ301_RS08380	COG0006	proline dipeptidase activity
SMQ301_RS08395	COG1131	(ABC) transporter
SMQ301_RS08470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SMQ301_RS08470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SMQ301_RS08495	COG0681	Belongs to the peptidase S26 family
SMQ301_RS08500	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SMQ301_RS08510	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SMQ301_RS08520	COG0456	acetyltransferase
SMQ301_RS08525	COG1214	PFAM Peptidase M22, glycoprotease
SMQ301_RS08545	COG0174	glutamine synthetase
SMQ301_RS08550	COG0789	Transcriptional regulator
SMQ301_RS08590	COG2801	Transposase and inactivated derivatives
SMQ301_RS08625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SMQ301_RS08670	COG0084	hydrolase, TatD family'
SMQ301_RS08680	COG3118	belongs to the thioredoxin family
SMQ301_RS08740	COG0706	membrane insertase activity
SMQ301_RS08800	COG0756	dUTP diphosphatase activity
SMQ301_RS08835	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SMQ301_RS08840	COG0705	Rhomboid family
SMQ301_RS08840	COG0457	Tetratricopeptide repeat
SMQ301_RS08845	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SMQ301_RS08865	COG2226	methyltransferase
SMQ301_RS08890	COG0425	Belongs to the sulfur carrier protein TusA family
SMQ301_RS08895	COG2391	methyltransferase activity
SMQ301_RS08900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SMQ301_RS08905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SMQ301_RS08915	COG1363	Peptidase, m42
SMQ301_RS08920	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SMQ301_RS08925	COG1266	CAAX protease self-immunity
SMQ301_RS08985	COG1459	type II secretion system
SMQ301_RS08990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SMQ301_RS09025	COG0440	acetolactate synthase activity
SMQ301_RS09030	COG0028	Belongs to the TPP enzyme family
SMQ301_RS09035	COG0129	dihydroxy-acid dehydratase activity
SMQ301_RS09040	COG1461	Dihydroxyacetone kinase
SMQ301_RS09050	COG0534	Mate efflux family protein
SMQ301_RS09070	COG1012	belongs to the aldehyde dehydrogenase family
SMQ301_RS09070	COG1454	alcohol dehydrogenase
SMQ301_RS09075	COG1454	alcohol dehydrogenase
SMQ301_RS09075	COG1012	belongs to the aldehyde dehydrogenase family
SMQ301_RS09080	COG1454	alcohol dehydrogenase
SMQ301_RS09080	COG1012	belongs to the aldehyde dehydrogenase family
SMQ301_RS09085	COG3590	peptidase
SMQ301_RS09090	COG0366	Alpha amylase catalytic
SMQ301_RS09095	COG0366	Alpha amylase catalytic
SMQ301_RS09100	COG0366	Alpha amylase catalytic
SMQ301_RS09110	COG1609	Transcriptional regulator
SMQ301_RS09115	COG2188	Transcriptional regulator
SMQ301_RS09120	COG4475	Protein of unknown function (DUF436)
SMQ301_RS09175	COG0191	fructose-bisphosphate aldolase activity
SMQ301_RS09235	COG0201	protein transport
SMQ301_RS09380	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SMQ301_RS09400	COG0515	serine threonine protein kinase
SMQ301_RS09405	COG1132	(ABC) transporter
SMQ301_RS09410	COG1396	sequence-specific DNA binding
SMQ301_RS09420	COG1132	(ABC) transporter
SMQ301_RS09455	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SMQ301_RS09500	COG0602	queuosine metabolic process
SMQ301_RS09510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SMQ301_RS09535	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SMQ301_RS09545	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SMQ301_RS09570	COG2261	transglycosylase associated protein
SMQ301_RS09590	COG3237	CsbD-like
SMQ301_RS09615	COG1511	domain protein
SMQ301_RS09615	COG1511	domain protein
SMQ301_RS09625	COG3759	membrane
SMQ301_RS09640	COG0305	Participates in initiation and elongation during chromosome replication
SMQ301_RS09670	COG0741	lytic transglycosylase activity
SMQ301_RS09675	COG3584	3D domain protein
SMQ301_RS09675	COG1388	LysM domain
SMQ301_RS09680	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SMQ301_RS09695	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SMQ301_RS09705	COG0612	Peptidase, M16
SMQ301_RS09735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SMQ301_RS09740	COG0488	(ABC) transporter
SMQ301_RS09775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain