locus-tag	class	description
MUB28_RS00010	COG0592	DNA-directed DNA polymerase activity
MUB28_RS00020	COG0012	GTP binding
MUB28_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MUB28_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MUB28_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MUB28_RS00195	COG3942	CHAP domain
MUB28_RS00210	COG0436	Aminotransferase
MUB28_RS00225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUB28_RS00235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MUB28_RS00250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MUB28_RS00265	COG1388	LysM domain
MUB28_RS00265	COG3942	CHAP domain
MUB28_RS00270	COG0151	Belongs to the GarS family
MUB28_RS00275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MUB28_RS00295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MUB28_RS00310	COG4550	Control of competence regulator ComK, YlbF/YmcA
MUB28_RS00355	COG2818	Glycosylase
MUB28_RS00365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MUB28_RS00370	COG1393	Belongs to the ArsC family
MUB28_RS00460	COG2309	aminopeptidase activity
MUB28_RS00475	COG0431	NADPH-dependent FMN reductase
MUB28_RS00510	COG4463	regulation of RNA biosynthetic process
MUB28_RS00515	COG0542	response to heat
MUB28_RS00530	COG1686	Belongs to the peptidase S11 family
MUB28_RS00545	COG1045	serine acetyltransferase
MUB28_RS00555	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MUB28_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUB28_RS00600	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MUB28_RS00685	COG3830	Belongs to the UPF0237 family
MUB28_RS00700	COG1876	peptidase activity
MUB28_RS00735	COG0351	phosphomethylpyrimidine kinase
MUB28_RS00775	COG4166	transmembrane transport
MUB28_RS00785	COG1473	amidohydrolase
MUB28_RS00790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MUB28_RS00810	COG0668	transmembrane transport
MUB28_RS00825	COG0504	CTP synthase activity
MUB28_RS00835	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MUB28_RS00845	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MUB28_RS00885	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MUB28_RS00925	COG1126	abc transporter atp-binding protein
MUB28_RS00930	COG0765	amino acid transport
MUB28_RS00935	COG1968	undecaprenyl-diphosphatase activity
MUB28_RS00945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MUB28_RS00955	COG0719	Fe-S assembly protein
MUB28_RS00960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MUB28_RS00970	COG0719	Fe-S assembly protein
MUB28_RS01010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MUB28_RS01025	COG1121	(ABC) transporter
MUB28_RS01030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MUB28_RS01070	COG4589	Belongs to the CDS family
MUB28_RS01085	COG4120	Belongs to the binding-protein-dependent transport system permease family
MUB28_RS01090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MUB28_RS01090	COG1116	anion transmembrane transporter activity
MUB28_RS01130	COG0564	pseudouridine synthase activity
MUB28_RS01135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUB28_RS01165	COG1349	DNA-binding transcription factor activity
MUB28_RS01190	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MUB28_RS01205	COG3579	cysteine-type endopeptidase activity
MUB28_RS01215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUB28_RS01240	COG0116	Belongs to the methyltransferase superfamily
MUB28_RS01250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MUB28_RS01270	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MUB28_RS01290	COG1254	Belongs to the acylphosphatase family
MUB28_RS01295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUB28_RS01340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MUB28_RS01360	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MUB28_RS01365	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MUB28_RS01370	COG1187	pseudouridine synthase activity
MUB28_RS01380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MUB28_RS01385	COG0569	domain protein
MUB28_RS01395	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MUB28_RS01400	COG0671	phosphoesterase, PA-phosphatase related
MUB28_RS01420	COG2274	protein secretion by the type I secretion system
MUB28_RS01480	COG0829	nickel cation binding
MUB28_RS01485	COG0310	cobalt ion transport
MUB28_RS01495	COG1122	ATPase activity
MUB28_RS01500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUB28_RS01505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUB28_RS01525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUB28_RS01530	COG1464	Belongs to the NlpA lipoprotein family
MUB28_RS01565	COG1122	ATPase activity
MUB28_RS01575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MUB28_RS01590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MUB28_RS01605	COG0745	RESPONSE REGULATOR receiver
MUB28_RS01610	COG5002	protein histidine kinase activity
MUB28_RS01625	COG1484	DNA-dependent DNA replication
MUB28_RS01665	COG3716	PTS system mannose fructose sorbose family IID component
MUB28_RS01670	COG3715	PTS system
MUB28_RS01680	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MUB28_RS01685	COG0561	phosphatase activity
MUB28_RS01690	COG2252	PERMEase
MUB28_RS01695	COG0802	atpase or kinase
MUB28_RS01700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUB28_RS01705	COG1316	TRANSCRIPTIONal
MUB28_RS01715	COG0195	Participates in both transcription termination and antitermination
MUB28_RS01720	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MUB28_RS01740	COG1611	Belongs to the LOG family
MUB28_RS01760	COG2244	polysaccharide biosynthetic process
MUB28_RS01765	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MUB28_RS01770	COG0626	cystathionine gamma-synthase activity
MUB28_RS01775	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MUB28_RS01810	COG0559	Belongs to the binding-protein-dependent transport system permease family
MUB28_RS01840	COG1739	Uncharacterized protein family UPF0029
MUB28_RS01845	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MUB28_RS01850	COG1040	competence protein
MUB28_RS01940	COG0527	aspartate kinase activity
MUB28_RS01945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MUB28_RS01950	COG1024	Enoyl-CoA hydratase
MUB28_RS01955	COG1846	Transcriptional regulator
MUB28_RS01975	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MUB28_RS01980	COG1028	Short-chain dehydrogenase reductase Sdr
MUB28_RS01985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MUB28_RS02000	COG0439	Biotin carboxylase
MUB28_RS02080	COG1349	DNA-binding transcription factor activity
MUB28_RS02085	COG1105	Belongs to the carbohydrate kinase PfkB family
MUB28_RS02095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUB28_RS02100	COG0285	dihydrofolate synthase activity
MUB28_RS02110	COG1104	cysteine desulfurase activity
MUB28_RS02170	COG0488	(ABC) transporter
MUB28_RS02190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MUB28_RS02195	COG0242	peptide deformylase activity
MUB28_RS02255	COG1702	phosphate starvation-inducible protein PhoH
MUB28_RS02280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUB28_RS02280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUB28_RS02300	COG4122	O-methyltransferase activity
MUB28_RS02305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MUB28_RS02340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MUB28_RS02345	COG0436	Aminotransferase
MUB28_RS02360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MUB28_RS02365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MUB28_RS02370	COG0726	polysaccharide deacetylase
MUB28_RS02385	COG2962	Rard protein
MUB28_RS02420	COG0356	it plays a direct role in the translocation of protons across the membrane
MUB28_RS02455	COG0772	Belongs to the SEDS family
MUB28_RS02475	COG0470	DNA polymerase III
MUB28_RS02480	COG1774	PSP1 C-terminal conserved region
MUB28_RS02485	COG4467	Involved in initiation control of chromosome replication
MUB28_RS02495	COG0004	ammonium transporteR
MUB28_RS02500	COG0347	Belongs to the P(II) protein family
MUB28_RS02505	COG1705	Flagellar rod assembly protein muramidase FlgJ
MUB28_RS02505	COG1388	LysM domain
MUB28_RS02565	COG1113	amino acid transport
MUB28_RS02610	COG0583	DNA-binding transcription factor activity
MUB28_RS02620	COG0564	pseudouridine synthase activity
MUB28_RS02640	COG0505	Belongs to the CarA family
MUB28_RS02670	COG0577	efflux transmembrane transporter activity
MUB28_RS02675	COG0577	efflux transmembrane transporter activity
MUB28_RS02690	COG3328	transposase activity
MUB28_RS02720	COG3279	Response regulator of the LytR AlgR family
MUB28_RS02730	COG1131	(ABC) transporter
MUB28_RS02765	COG1187	pseudouridine synthase activity
MUB28_RS02770	COG1473	amidohydrolase
MUB28_RS02775	COG0686	Belongs to the AlaDH PNT family
MUB28_RS02785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUB28_RS02850	COG0438	transferase activity, transferring glycosyl groups
MUB28_RS02885	COG1272	protein, Hemolysin III
MUB28_RS02900	COG3425	synthase
MUB28_RS02910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MUB28_RS02930	COG0833	amino acid
MUB28_RS02935	COG2040	homocysteine
MUB28_RS02955	COG0187	DNA topoisomerase II activity
MUB28_RS02965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MUB28_RS02985	COG0539	negative regulation of cytoplasmic translation
MUB28_RS03025	COG0494	nUDIX hydrolase
MUB28_RS03030	COG0542	response to heat
MUB28_RS03035	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MUB28_RS03040	COG4703	Protein of unknown function (DUF1797)
MUB28_RS03045	COG0765	amino acid transport
MUB28_RS03100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MUB28_RS03105	COG0768	penicillin binding
MUB28_RS03110	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MUB28_RS03125	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MUB28_RS03130	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MUB28_RS03135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MUB28_RS03140	COG0237	dephospho-CoA kinase activity
MUB28_RS03145	COG2814	Major facilitator Superfamily
MUB28_RS03160	COG0557	exoribonuclease II activity
MUB28_RS03175	COG1185	polyribonucleotide nucleotidyltransferase activity
MUB28_RS03180	COG0006	proline dipeptidase activity
MUB28_RS03185	COG1609	Transcriptional regulator
MUB28_RS03225	COG1368	sulfuric ester hydrolase activity
MUB28_RS03230	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MUB28_RS03255	COG0287	Prephenate dehydrogenase
MUB28_RS03280	COG0077	Prephenate dehydratase
MUB28_RS03340	COG1518	maintenance of DNA repeat elements
MUB28_RS03345	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MUB28_RS03355	COG3689	TIGRFAM TIGR03943 family protein
MUB28_RS03360	COG0701	Predicted permease
MUB28_RS03365	COG2183	response to ionizing radiation
MUB28_RS03410	COG0826	peptidase U32
MUB28_RS03420	COG1268	BioY protein
MUB28_RS03430	COG4443	Transcriptional Coactivator p15 (PC4)
MUB28_RS03435	COG1914	H( )-stimulated, divalent metal cation uptake system
MUB28_RS03470	COG1705	Flagellar rod assembly protein muramidase FlgJ
MUB28_RS03470	COG1388	LysM domain
MUB28_RS03485	COG0406	alpha-ribazole phosphatase activity
MUB28_RS03490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MUB28_RS03530	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MUB28_RS03550	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
MUB28_RS03555	COG3620	sequence-specific DNA binding
MUB28_RS03580	COG1704	LemA family
MUB28_RS03585	COG0501	Belongs to the peptidase M48B family
MUB28_RS03600	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MUB28_RS03610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MUB28_RS03625	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MUB28_RS03630	COG0783	Belongs to the Dps family
MUB28_RS03635	COG0735	belongs to the Fur family
MUB28_RS03640	COG4483	Protein conserved in bacteria
MUB28_RS03645	COG1940	carbohydrate kinase activity
MUB28_RS03650	COG1217	gtp-binding protein TYPA
MUB28_RS03685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MUB28_RS03710	COG3599	regulation of cell shape
MUB28_RS03740	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MUB28_RS03745	COG0625	glutathione transferase activity
MUB28_RS03750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MUB28_RS03765	COG2890	protein-(glutamine-N5) methyltransferase activity
MUB28_RS03795	COG1132	(ABC) transporter
MUB28_RS03810	COG1696	Membrane protein involved in D-alanine export
MUB28_RS03820	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MUB28_RS03830	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MUB28_RS03835	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MUB28_RS03895	COG1396	sequence-specific DNA binding
MUB28_RS03900	COG0582	viral genome integration into host DNA
MUB28_RS03960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MUB28_RS03985	COG0765	amino acid transport
MUB28_RS03990	COG0765	amino acid transport
MUB28_RS03995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUB28_RS04000	COG1126	abc transporter atp-binding protein
MUB28_RS04005	COG0745	RESPONSE REGULATOR receiver
MUB28_RS04010	COG5002	protein histidine kinase activity
MUB28_RS04015	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MUB28_RS04025	COG2348	transferase activity, transferring amino-acyl groups
MUB28_RS04060	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MUB28_RS04070	COG2884	Cell division ATP-binding protein ftsE
MUB28_RS04075	COG2177	Part of the ABC transporter FtsEX involved in
MUB28_RS04080	COG1051	belongs to the nudix hydrolase family
MUB28_RS04085	COG0628	permease
MUB28_RS04095	COG0681	Belongs to the peptidase S26 family
MUB28_RS04160	COG1573	uracil-dna glycosylase
MUB28_RS04180	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MUB28_RS04210	COG1316	TRANSCRIPTIONal
MUB28_RS04250	COG0562	UDP-galactopyranose mutase
MUB28_RS04260	COG1442	glycosyl transferase family 8
MUB28_RS04260	COG1216	Glycosyl transferase, family 2
MUB28_RS04320	COG1316	TRANSCRIPTIONal
MUB28_RS04350	COG2244	polysaccharide biosynthetic process
MUB28_RS04360	COG1442	glycosyl transferase family 8
MUB28_RS04360	COG1216	Glycosyl transferase, family 2
MUB28_RS04370	COG0438	transferase activity, transferring glycosyl groups
MUB28_RS04375	COG0561	phosphatase activity
MUB28_RS04385	COG0628	permease
MUB28_RS04415	COG4667	esterase of the alpha-beta hydrolase superfamily
MUB28_RS04420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MUB28_RS04445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MUB28_RS04450	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUB28_RS04450	COG0022	dehydrogenase e1 component
MUB28_RS04455	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUB28_RS04475	COG2822	iron ion transport
MUB28_RS04480	COG2837	iron assimilation
MUB28_RS04485	COG0672	)-iron permease
MUB28_RS04490	COG0805	protein transport
MUB28_RS04495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MUB28_RS04510	COG1609	Transcriptional regulator
MUB28_RS04515	COG1640	4-alpha-glucanotransferase
MUB28_RS04520	COG0058	SHG alpha-glucan phosphorylase activity
MUB28_RS04535	COG0095	Lipoate-protein ligase
MUB28_RS04550	COG0704	Plays a role in the regulation of phosphate uptake
MUB28_RS04565	COG0581	inorganic phosphate transmembrane transporter activity
MUB28_RS04570	COG0573	inorganic phosphate transmembrane transporter activity
MUB28_RS04580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MUB28_RS04580	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
MUB28_RS04585	COG0483	inositol monophosphate 1-phosphatase activity
MUB28_RS04595	COG1393	Belongs to the ArsC family
MUB28_RS04600	COG0196	riboflavin kinase activity
MUB28_RS04605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MUB28_RS04635	COG2873	o-acetylhomoserine
MUB28_RS04645	COG1115	amino acid carrier protein
MUB28_RS04675	COG0737	Belongs to the 5'-nucleotidase family
MUB28_RS04690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUB28_RS04700	COG3104	oligopeptide transport
MUB28_RS04715	COG0284	orotidine-5'-phosphate decarboxylase activity
MUB28_RS04730	COG1567	CRISPR-associated RAMP protein, Csm4 family
MUB28_RS04735	COG1337	RAMP superfamily
MUB28_RS04755	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MUB28_RS04765	COG0167	dihydroorotate dehydrogenase activity
MUB28_RS04775	COG0047	phosphoribosylformylglycinamidine synthase activity
MUB28_RS04810	COG1293	RNA-binding protein homologous to eukaryotic snRNP
MUB28_RS04830	COG4607	ABC-type enterochelin transport system periplasmic component
MUB28_RS04835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MUB28_RS04855	COG1063	alcohol dehydrogenase
MUB28_RS04865	COG1230	cation diffusion facilitator family transporter
MUB28_RS04890	COG3527	Alpha-acetolactate decarboxylase
MUB28_RS04895	COG0028	Belongs to the TPP enzyme family
MUB28_RS04905	COG0010	Belongs to the arginase family
MUB28_RS04910	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MUB28_RS04925	COG1396	sequence-specific DNA binding
MUB28_RS04930	COG0481	GTPase activity
MUB28_RS04955	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MUB28_RS04975	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MUB28_RS04980	COG0758	DNA mediated transformation
MUB28_RS04985	COG1940	carbohydrate kinase activity
MUB28_RS04995	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MUB28_RS05005	COG1827	regulation of RNA biosynthetic process
MUB28_RS05015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MUB28_RS05025	COG2188	Transcriptional regulator
MUB28_RS05030	COG0519	Catalyzes the synthesis of GMP from XMP
MUB28_RS05030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MUB28_RS05040	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MUB28_RS05065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUB28_RS05070	COG1126	abc transporter atp-binding protein
MUB28_RS05075	COG0765	amino acid transport
MUB28_RS05080	COG2824	Alkylphosphonate utilization operon protein PhnA
MUB28_RS05085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MUB28_RS05100	COG3942	CHAP domain
MUB28_RS05100	COG1705	Flagellar rod assembly protein muramidase FlgJ
MUB28_RS05115	COG3443	Belongs to the bacterial solute-binding protein 9 family
MUB28_RS05115	COG0803	Belongs to the bacterial solute-binding protein 9 family
MUB28_RS05135	COG4975	Glucose uptake
MUB28_RS05145	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MUB28_RS05165	COG1045	serine acetyltransferase
MUB28_RS05170	COG0626	cystathionine gamma-synthase activity
MUB28_RS05175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MUB28_RS05190	COG2217	Heavy metal translocating P-type atpase
MUB28_RS05205	COG1278	Cold shock
MUB28_RS05255	COG0720	synthase
MUB28_RS05265	COG0251	oxidation-reduction process
MUB28_RS05280	COG0017	Asparaginyl-tRNA synthetase
MUB28_RS05285	COG0436	Aminotransferase
MUB28_RS05295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MUB28_RS05295	COG1199	ATP-dependent helicase activity
MUB28_RS05305	COG1079	Belongs to the binding-protein-dependent transport system permease family
MUB28_RS05310	COG4603	Belongs to the binding-protein-dependent transport system permease family
MUB28_RS05315	COG3845	ABC transporter
MUB28_RS05320	COG1744	ABC transporter substrate-binding protein PnrA-like
MUB28_RS05325	COG0295	cytidine deaminase activity
MUB28_RS05340	COG2813	Specifically methylates the guanine in position
MUB28_RS05370	COG0038	chloride channel
MUB28_RS05415	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MUB28_RS05420	COG4684	Psort location CytoplasmicMembrane, score
MUB28_RS05425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MUB28_RS05440	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MUB28_RS05445	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MUB28_RS05445	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MUB28_RS05455	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MUB28_RS05460	COG1956	GAF domain-containing protein
MUB28_RS05465	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MUB28_RS05480	COG0335	large ribosomal subunit rRNA binding
MUB28_RS05485	COG0038	chloride channel
MUB28_RS05495	COG0038	chloride channel
MUB28_RS05500	COG0716	FMN binding
MUB28_RS05565	COG3328	transposase activity
MUB28_RS05575	COG0469	pyruvate kinase activity
MUB28_RS05625	COG0167	dihydroorotate dehydrogenase activity
MUB28_RS05635	COG0776	regulation of translation
MUB28_RS05645	COG2755	lipolytic protein G-D-S-L family
MUB28_RS05650	COG1307	EDD domain protein, DegV family
MUB28_RS05655	COG0497	DNA recombination
MUB28_RS05660	COG1438	arginine binding
MUB28_RS05665	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MUB28_RS05690	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MUB28_RS05710	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MUB28_RS05710	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MUB28_RS05715	COG0300	oxidoreductase activity
MUB28_RS05730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MUB28_RS05750	COG0107	imidazoleglycerol-phosphate synthase activity
MUB28_RS05760	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MUB28_RS05770	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MUB28_RS05815	COG0647	UMP catabolic process
MUB28_RS05825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MUB28_RS05845	COG1088	dTDP-glucose 4,6-dehydratase activity
MUB28_RS05855	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MUB28_RS05860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUB28_RS05875	COG2384	SAM-dependent methyltransferase
MUB28_RS05900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MUB28_RS05905	COG3442	glutamine amidotransferase
MUB28_RS05910	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MUB28_RS05910	COG0392	lysyltransferase activity
MUB28_RS05920	COG0488	(ABC) transporter
MUB28_RS05930	COG0513	Belongs to the DEAD box helicase family
MUB28_RS05965	COG0372	Belongs to the citrate synthase family
MUB28_RS05970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MUB28_RS05975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MUB28_RS05980	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUB28_RS05985	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUB28_RS06015	COG3764	Sortase (surface protein transpeptidase)
MUB28_RS06035	COG0488	(ABC) transporter
MUB28_RS06060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUB28_RS06065	COG1328	CTP reductase activity
MUB28_RS06065	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MUB28_RS06090	COG1196	nuclear chromosome segregation
MUB28_RS06105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MUB28_RS06120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MUB28_RS06130	COG1011	Hydrolase
MUB28_RS06135	COG1268	BioY protein
MUB28_RS06145	COG0517	IMP dehydrogenase activity
MUB28_RS06145	COG1125	glycine betaine transport
MUB28_RS06160	COG2986	histidine ammonia-lyase
MUB28_RS06170	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MUB28_RS06175	COG1760	l-serine dehydratase
MUB28_RS06205	COG2197	response regulator
MUB28_RS06210	COG4585	Histidine kinase
MUB28_RS06220	COG1131	(ABC) transporter
MUB28_RS06235	COG0385	Bile acid
MUB28_RS06250	COG1131	(ABC) transporter
MUB28_RS06270	COG0577	efflux transmembrane transporter activity
MUB28_RS06275	COG1136	(ABC) transporter
MUB28_RS06280	COG2198	Histidine kinase
MUB28_RS06280	COG5002	protein histidine kinase activity
MUB28_RS06280	COG0784	Response regulator, receiver
MUB28_RS06285	COG0745	RESPONSE REGULATOR receiver
MUB28_RS06300	COG0534	Mate efflux family protein
MUB28_RS06305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MUB28_RS06305	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MUB28_RS06330	COG0531	amino acid
MUB28_RS06340	COG2514	catechol 2,3-dioxygenase activity
MUB28_RS06345	COG1959	2 iron, 2 sulfur cluster binding
MUB28_RS06355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MUB28_RS06360	COG0778	Nitroreductase
MUB28_RS06370	COG0656	L-ascorbic acid biosynthetic process
MUB28_RS06410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MUB28_RS06435	COG1280	lysine exporter protein (LysE YggA)
MUB28_RS06445	COG1442	glycosyl transferase family 8
MUB28_RS06445	COG1216	Glycosyl transferase, family 2
MUB28_RS06450	COG0577	efflux transmembrane transporter activity
MUB28_RS06500	COG1396	sequence-specific DNA binding
MUB28_RS06520	COG0419	ATPase involved in DNA repair
MUB28_RS06525	COG0420	3'-5' exonuclease activity
MUB28_RS06535	COG3250	beta-galactosidase activity
MUB28_RS06540	COG2211	Major facilitator Superfamily
MUB28_RS06540	COG2190	(PTS) system
MUB28_RS06545	COG2017	converts alpha-aldose to the beta-anomer
MUB28_RS06550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MUB28_RS06565	COG1609	Transcriptional regulator
MUB28_RS06645	COG2197	response regulator
MUB28_RS06650	COG4585	Histidine kinase
MUB28_RS06665	COG0515	serine threonine protein kinase
MUB28_RS06665	COG2815	serine threonine protein kinase
MUB28_RS06675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MUB28_RS06675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MUB28_RS06685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MUB28_RS06700	COG0552	protein localization to endoplasmic reticulum
MUB28_RS06705	COG0561	phosphatase activity
MUB28_RS06710	COG0561	phosphatase activity
MUB28_RS06715	COG1725	Transcriptional regulator
MUB28_RS06720	COG1131	(ABC) transporter
MUB28_RS06730	COG4608	Belongs to the ABC transporter superfamily
MUB28_RS06735	COG0444	Belongs to the ABC transporter superfamily
MUB28_RS06740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUB28_RS06745	COG0601	transmembrane transport
MUB28_RS06750	COG4166	transmembrane transport
MUB28_RS06760	COG4166	transmembrane transport
MUB28_RS06785	COG2223	nitrite transmembrane transporter activity
MUB28_RS06795	COG0280	phosphate acetyltransferase
MUB28_RS06800	COG0564	pseudouridine synthase activity
MUB28_RS06810	COG2357	RelA SpoT domain protein
MUB28_RS06825	COG1104	cysteine desulfurase activity
MUB28_RS06840	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MUB28_RS06845	COG2003	Belongs to the UPF0758 family
MUB28_RS06870	COG1215	transferase activity, transferring glycosyl groups
MUB28_RS06880	COG1442	glycosyl transferase family 8
MUB28_RS06880	COG1216	Glycosyl transferase, family 2
MUB28_RS06900	COG1091	dTDP-4-dehydrorhamnose reductase activity
MUB28_RS06910	COG0463	Glycosyl transferase, family 2
MUB28_RS06920	COG2151	metal-sulfur cluster biosynthetic enzyme
MUB28_RS06925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MUB28_RS06930	COG0358	DNA primase activity
MUB28_RS06945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUB28_RS06950	COG0436	Aminotransferase
MUB28_RS06955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUB28_RS06960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUB28_RS06965	COG1051	belongs to the nudix hydrolase family
MUB28_RS06985	COG0765	amino acid transport
MUB28_RS06990	COG1126	abc transporter atp-binding protein
MUB28_RS07010	COG1187	pseudouridine synthase activity
MUB28_RS07055	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MUB28_RS07060	COG1518	maintenance of DNA repeat elements
MUB28_RS07065	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MUB28_RS07070	COG0560	Phosphoserine phosphatase
MUB28_RS07080	COG0187	DNA topoisomerase II activity
MUB28_RS07090	COG1346	cytolysis
MUB28_RS07095	COG1380	Effector of murein hydrolase LrgA
MUB28_RS07105	COG1393	Belongs to the ArsC family
MUB28_RS07115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MUB28_RS07150	COG1177	transmembrane transport
MUB28_RS07155	COG1176	ABC-type spermidine putrescine transport system, permease component I
MUB28_RS07195	COG0531	amino acid
MUB28_RS07200	COG0285	dihydrofolate synthase activity
MUB28_RS07205	COG1837	Belongs to the UPF0109 family
MUB28_RS07215	COG3615	Tellurite resistance protein tehB
MUB28_RS07215	COG0500	methyltransferase
MUB28_RS07225	COG0708	Exodeoxyribonuclease III
MUB28_RS07240	COG1597	lipid kinase activity
MUB28_RS07250	COG4708	membrane
MUB28_RS07260	COG0024	Methionine aminopeptidase
MUB28_RS07265	COG4109	DRTGG domain
MUB28_RS07275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MUB28_RS07280	COG0658	competence protein
MUB28_RS07280	COG2333	competence protein COMEC
MUB28_RS07285	COG1555	photosystem II stabilization
MUB28_RS07285	COG1596	polysaccharide export
MUB28_RS07290	COG0204	Acyl-transferase
MUB28_RS07300	COG0726	polysaccharide deacetylase
MUB28_RS07305	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MUB28_RS07315	COG0513	Belongs to the DEAD box helicase family
MUB28_RS07335	COG1396	sequence-specific DNA binding
MUB28_RS07340	COG2211	Major facilitator Superfamily
MUB28_RS07355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MUB28_RS07370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUB28_RS07375	COG1126	abc transporter atp-binding protein
MUB28_RS07380	COG0765	amino acid transport
MUB28_RS07385	COG0765	amino acid transport
MUB28_RS07400	COG2217	Heavy metal translocating P-type atpase
MUB28_RS07410	COG0159	tryptophan synthase activity
MUB28_RS07420	COG0135	phosphoribosylanthranilate isomerase activity
MUB28_RS07435	COG0512	Glutamine amidotransferase of anthranilate synthase
MUB28_RS07440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MUB28_RS07445	COG0287	Prephenate dehydrogenase
MUB28_RS07445	COG1605	Chorismate mutase
MUB28_RS07455	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MUB28_RS07480	COG2176	DNA-directed DNA polymerase activity
MUB28_RS07490	COG2151	metal-sulfur cluster biosynthetic enzyme
MUB28_RS07500	COG2081	HI0933 family
MUB28_RS07525	COG1131	(ABC) transporter
MUB28_RS07530	COG0537	adenosine 5'-monophosphoramidase activity
MUB28_RS07560	COG2226	methyltransferase
MUB28_RS07565	COG0799	negative regulation of ribosome biogenesis
MUB28_RS07570	COG1713	HD superfamily hydrolase involved in NAD metabolism
MUB28_RS07575	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MUB28_RS07580	COG1534	Rna-binding protein
MUB28_RS07585	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MUB28_RS07590	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MUB28_RS07645	COG1335	isochorismatase
MUB28_RS07655	COG0436	Aminotransferase
MUB28_RS07660	COG0589	response to stress
MUB28_RS07680	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MUB28_RS07690	COG1253	flavin adenine dinucleotide binding
MUB28_RS07695	COG1119	ATPase activity
MUB28_RS07700	COG0025	NhaP-type Na H and K H
MUB28_RS07710	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MUB28_RS07715	COG1242	4 iron, 4 sulfur cluster binding
MUB28_RS07720	COG3480	Lon protease (S16) C-terminal proteolytic domain
MUB28_RS07725	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MUB28_RS07730	COG0742	ribosomal rna small subunit methyltransferase
MUB28_RS07735	COG0492	ferredoxin-NADP+ reductase activity
MUB28_RS07745	COG1126	abc transporter atp-binding protein
MUB28_RS07755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUB28_RS07770	COG1882	Formate acetyltransferase
MUB28_RS07795	COG0390	transport system, permease component
MUB28_RS07800	COG4619	ABC transporter
MUB28_RS07805	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MUB28_RS07820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MUB28_RS07895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MUB28_RS07900	COG2274	protein secretion by the type I secretion system
MUB28_RS07905	COG1132	(ABC) transporter
MUB28_RS07910	COG1132	(ABC) transporter
MUB28_RS07930	COG4470	Protein conserved in bacteria
MUB28_RS07935	COG0737	Belongs to the 5'-nucleotidase family
MUB28_RS07940	COG0513	Belongs to the DEAD box helicase family
MUB28_RS07950	COG0768	penicillin binding
MUB28_RS07980	COG3152	Membrane
MUB28_RS07990	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MUB28_RS08005	COG4152	abc transporter atp-binding protein
MUB28_RS08010	COG1811	Na channel or pump
MUB28_RS08015	COG1074	ATP-dependent DNA helicase activity
MUB28_RS08055	COG0561	phosphatase activity
MUB28_RS08060	COG0252	asparaginase activity
MUB28_RS08065	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MUB28_RS08070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MUB28_RS08080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MUB28_RS08085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MUB28_RS08100	COG1482	cell wall glycoprotein biosynthetic process
MUB28_RS08105	COG1940	carbohydrate kinase activity
MUB28_RS08110	COG1263	PTS System
MUB28_RS08110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUB28_RS08110	COG2190	(PTS) system
MUB28_RS08115	COG1621	beta-fructofuranosidase activity
MUB28_RS08120	COG1609	Transcriptional regulator
MUB28_RS08140	COG2131	deaminase
MUB28_RS08145	COG0006	proline dipeptidase activity
MUB28_RS08160	COG1131	(ABC) transporter
MUB28_RS08235	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUB28_RS08235	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUB28_RS08260	COG0681	Belongs to the peptidase S26 family
MUB28_RS08265	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MUB28_RS08275	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MUB28_RS08285	COG0456	acetyltransferase
MUB28_RS08290	COG1214	PFAM Peptidase M22, glycoprotease
MUB28_RS08310	COG0174	glutamine synthetase
MUB28_RS08315	COG0789	Transcriptional regulator
MUB28_RS08370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MUB28_RS08415	COG0084	hydrolase, TatD family'
MUB28_RS08420	COG1832	CoA-binding protein
MUB28_RS08425	COG3118	belongs to the thioredoxin family
MUB28_RS08490	COG0706	membrane insertase activity
MUB28_RS08550	COG0756	dUTP diphosphatase activity
MUB28_RS08580	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MUB28_RS08585	COG0457	Tetratricopeptide repeat
MUB28_RS08585	COG0705	Rhomboid family
MUB28_RS08590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MUB28_RS08605	COG0647	UMP catabolic process
MUB28_RS08615	COG2226	methyltransferase
MUB28_RS08640	COG0425	Belongs to the sulfur carrier protein TusA family
MUB28_RS08645	COG2391	methyltransferase activity
MUB28_RS08650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUB28_RS08655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUB28_RS08665	COG1363	Peptidase, m42
MUB28_RS08670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MUB28_RS08675	COG1266	CAAX protease self-immunity
MUB28_RS08730	COG1459	type II secretion system
MUB28_RS08735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MUB28_RS08770	COG0440	acetolactate synthase activity
MUB28_RS08775	COG0028	Belongs to the TPP enzyme family
MUB28_RS08785	COG1461	Dihydroxyacetone kinase
MUB28_RS08795	COG0534	Mate efflux family protein
MUB28_RS08810	COG3590	peptidase
MUB28_RS08830	COG4475	Protein of unknown function (DUF436)
MUB28_RS08865	COG1301	dicarboxylic acid transport
MUB28_RS08935	COG0191	fructose-bisphosphate aldolase activity
MUB28_RS08995	COG0201	protein transport
MUB28_RS09140	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MUB28_RS09155	COG0515	serine threonine protein kinase
MUB28_RS09160	COG1132	(ABC) transporter
MUB28_RS09170	COG0535	radical SAM domain protein
MUB28_RS09180	COG1132	(ABC) transporter
MUB28_RS09205	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MUB28_RS09235	COG1328	CTP reductase activity
MUB28_RS09245	COG0602	queuosine metabolic process
MUB28_RS09255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MUB28_RS09285	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MUB28_RS09310	COG2261	transglycosylase associated protein
MUB28_RS09330	COG3237	CsbD-like
MUB28_RS09355	COG1511	domain protein
MUB28_RS09355	COG1511	domain protein
MUB28_RS09365	COG3759	membrane
MUB28_RS09385	COG0305	Participates in initiation and elongation during chromosome replication
MUB28_RS09405	COG0494	nUDIX hydrolase
MUB28_RS09420	COG0741	lytic transglycosylase activity
MUB28_RS09425	COG1388	LysM domain
MUB28_RS09425	COG3584	3D domain protein
MUB28_RS09430	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MUB28_RS09445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MUB28_RS09455	COG0612	Peptidase, M16
MUB28_RS09485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MUB28_RS09490	COG0488	(ABC) transporter
MUB28_RS09525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MUB28_RS09530	COG1475	DNA binding