locus-tag	class	description
STYK_RS00010	COG0592	DNA-directed DNA polymerase activity
STYK_RS00020	COG0012	GTP binding
STYK_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
STYK_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
STYK_RS00060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
STYK_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
STYK_RS00125	COG0756	dUTP diphosphatase activity
STYK_RS00135	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
STYK_RS00150	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
STYK_RS00190	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STYK_RS00190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STYK_RS00195	COG1832	CoA-binding protein
STYK_RS00200	COG2855	membrane
STYK_RS00205	COG0436	Aminotransferase
STYK_RS00220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
STYK_RS00230	COG0791	NLP P60 protein
STYK_RS00280	COG2274	protein secretion by the type I secretion system
STYK_RS00285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
STYK_RS00295	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
STYK_RS00300	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
STYK_RS00305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
STYK_RS00310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
STYK_RS00325	COG0138	bifunctional purine biosynthesis protein purh
STYK_RS00330	COG0151	Belongs to the GarS family
STYK_RS00335	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
STYK_RS00340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
STYK_RS00365	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
STYK_RS00370	COG3064	Membrane
STYK_RS00370	COG3525	Glycosyl hydrolase, family 20, catalytic domain
STYK_RS00370	COG3583	domain protein
STYK_RS00385	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STYK_RS00390	COG3715	PTS system
STYK_RS00395	COG3716	PTS system mannose fructose sorbose family IID component
STYK_RS00410	COG2222	sugar isomerase
STYK_RS00485	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STYK_RS00490	COG0569	domain protein
STYK_RS00500	COG1215	transferase activity, transferring glycosyl groups
STYK_RS00515	COG5002	protein histidine kinase activity
STYK_RS00565	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
STYK_RS00570	COG3177	Filamentation induced by cAMP protein fic
STYK_RS00600	COG0515	serine threonine protein kinase
STYK_RS00600	COG2815	serine threonine protein kinase
STYK_RS00620	COG0267	Belongs to the bacterial ribosomal protein bL33 family
STYK_RS00630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STYK_RS00645	COG3959	Transketolase, thiamine diphosphate binding domain
STYK_RS00650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
STYK_RS00660	COG2151	metal-sulfur cluster biosynthetic enzyme
STYK_RS00685	COG1476	TRANSCRIPTIONal
STYK_RS00730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
STYK_RS00735	COG1609	Transcriptional regulator
STYK_RS00740	COG5521	maltodextrose utilization protein MalA
STYK_RS00745	COG3833	ABC-type maltose transport systems, permease component
STYK_RS00750	COG1175	transmembrane transport
STYK_RS00755	COG2182	Extracellular solute-binding protein
STYK_RS00760	COG1640	4-alpha-glucanotransferase
STYK_RS00765	COG0058	SHG alpha-glucan phosphorylase activity
STYK_RS00775	COG2226	methyltransferase
STYK_RS00785	COG2217	Heavy metal translocating P-type atpase
STYK_RS00795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STYK_RS00795	COG4499	WXG100 protein secretion system (Wss), protein YukC
STYK_RS00800	COG0697	spore germination
STYK_RS00815	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
STYK_RS00830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
STYK_RS00850	COG1438	arginine binding
STYK_RS00860	COG1132	(ABC) transporter
STYK_RS00865	COG1132	(ABC) transporter
STYK_RS00870	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
STYK_RS00875	COG0166	Belongs to the GPI family
STYK_RS00985	COG0534	Mate efflux family protein
STYK_RS01005	COG3759	membrane
STYK_RS01010	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
STYK_RS01035	COG1063	alcohol dehydrogenase
STYK_RS01045	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STYK_RS01050	COG1459	type II secretion system
STYK_RS01055	COG4537	Required for transformation and DNA binding
STYK_RS01100	COG0706	membrane insertase activity
STYK_RS01120	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
STYK_RS01125	COG1862	Preprotein translocase
STYK_RS01130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
STYK_RS01140	COG1454	alcohol dehydrogenase
STYK_RS01140	COG1012	belongs to the aldehyde dehydrogenase family
STYK_RS01150	COG0564	pseudouridine synthase activity
STYK_RS01155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STYK_RS01160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
STYK_RS01260	COG1131	(ABC) transporter
STYK_RS01265	COG0842	Transport permease protein
STYK_RS01270	COG4585	Histidine kinase
STYK_RS01275	COG2197	response regulator
STYK_RS01295	COG2176	DNA-directed DNA polymerase activity
STYK_RS01305	COG2309	aminopeptidase activity
STYK_RS01310	COG2261	transglycosylase associated protein
STYK_RS01320	COG1187	pseudouridine synthase activity
STYK_RS01325	COG3579	cysteine-type endopeptidase activity
STYK_RS01330	COG3716	PTS system mannose fructose sorbose family IID component
STYK_RS01335	COG3715	PTS system
STYK_RS01345	COG1064	alcohol dehydrogenase
STYK_RS01350	COG0561	phosphatase activity
STYK_RS01355	COG2252	PERMEase
STYK_RS01365	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
STYK_RS01370	COG0285	dihydrofolate synthase activity
STYK_RS01380	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
STYK_RS01380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
STYK_RS01390	COG1609	Transcriptional regulator
STYK_RS01395	COG0252	asparaginase activity
STYK_RS01400	COG0561	phosphatase activity
STYK_RS01410	COG0589	response to stress
STYK_RS01420	COG0436	Aminotransferase
STYK_RS01430	COG4166	transmembrane transport
STYK_RS01440	COG0531	amino acid
STYK_RS01445	COG0084	hydrolase, TatD family'
STYK_RS01470	COG1136	(ABC) transporter
STYK_RS01470	COG0577	efflux transmembrane transporter activity
STYK_RS01485	COG1162	GTPase activity
STYK_RS01495	COG1564	THIamine pyrophosphokinase
STYK_RS01505	COG3481	metal-dependent phosphohydrolase, HD sub domain
STYK_RS01510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
STYK_RS01520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
STYK_RS01555	COG1254	Belongs to the acylphosphatase family
STYK_RS01560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STYK_RS01575	COG0742	ribosomal rna small subunit methyltransferase
STYK_RS01585	COG3480	Lon protease (S16) C-terminal proteolytic domain
STYK_RS01595	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
STYK_RS01610	COG1253	flavin adenine dinucleotide binding
STYK_RS01620	COG4166	transmembrane transport
STYK_RS01625	COG0601	transmembrane transport
STYK_RS01630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
STYK_RS01635	COG0444	Belongs to the ABC transporter superfamily
STYK_RS01640	COG4608	Belongs to the ABC transporter superfamily
STYK_RS01650	COG4120	Belongs to the binding-protein-dependent transport system permease family
STYK_RS01655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
STYK_RS01660	COG2188	Transcriptional regulator
STYK_RS01665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STYK_RS01665	COG1263	PTS System
STYK_RS01670	COG0366	Alpha amylase catalytic
STYK_RS01685	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
STYK_RS01715	COG1187	pseudouridine synthase activity
STYK_RS01730	COG4607	ABC-type enterochelin transport system periplasmic component
STYK_RS01735	COG4604	ABC transporter, ATP-binding protein
STYK_RS01740	COG4605	iron ion homeostasis
STYK_RS01745	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
STYK_RS01750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STYK_RS01755	COG1363	Peptidase, m42
STYK_RS01765	COG1283	sodium-dependent phosphate transmembrane transporter activity
STYK_RS01785	COG0789	Transcriptional regulator
STYK_RS01790	COG0174	glutamine synthetase
STYK_RS01830	COG0484	heat shock protein binding
STYK_RS01845	COG0537	adenosine 5'-monophosphoramidase activity
STYK_RS01850	COG1131	(ABC) transporter
STYK_RS01855	COG4473	ABC transporter
STYK_RS01875	COG3290	protein histidine kinase activity
STYK_RS01885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
STYK_RS01890	COG2274	protein secretion by the type I secretion system
STYK_RS01970	COG1266	CAAX protease self-immunity
STYK_RS01990	COG0195	Participates in both transcription termination and antitermination
STYK_RS01995	COG2740	Nucleic-acid-binding protein implicated in transcription termination
STYK_RS02050	COG0519	Catalyzes the synthesis of GMP from XMP
STYK_RS02060	COG0525	valine-tRNA ligase activity
STYK_RS02070	COG1204	response to ionizing radiation
STYK_RS02095	COG0504	CTP synthase activity
STYK_RS02110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STYK_RS02115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STYK_RS02120	COG4221	oxidoreductase activity
STYK_RS02155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
STYK_RS02275	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
STYK_RS02275	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
STYK_RS02280	COG2207	Transcriptional regulator
STYK_RS02285	COG3345	alpha-galactosidase
STYK_RS02290	COG1653	transport
STYK_RS02295	COG1175	transmembrane transport
STYK_RS02300	COG0395	ABC-type sugar transport system, permease component
STYK_RS02305	COG0366	Alpha amylase catalytic
STYK_RS02330	COG1174	glycine betaine transport
STYK_RS02335	COG1131	(ABC) transporter
STYK_RS02360	COG1230	cation diffusion facilitator family transporter
STYK_RS02365	COG0789	Transcriptional regulator
STYK_RS02370	COG1063	alcohol dehydrogenase
STYK_RS02375	COG1609	Transcriptional regulator
STYK_RS02380	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
STYK_RS02385	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
STYK_RS02395	COG2233	PERMEase
STYK_RS02410	COG0708	Exodeoxyribonuclease III
STYK_RS02420	COG0640	Transcriptional regulator
STYK_RS02440	COG1132	(ABC) transporter
STYK_RS02445	COG1132	(ABC) transporter
STYK_RS02450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
STYK_RS02455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
STYK_RS02460	COG5434	Belongs to the glycosyl hydrolase 28 family
STYK_RS02470	COG0704	Plays a role in the regulation of phosphate uptake
STYK_RS02475	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
STYK_RS02480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STYK_RS02500	COG1178	ABC-type Fe3 transport system permease component
STYK_RS02505	COG1285	pathogenesis
STYK_RS02515	COG0133	tryptophan synthase activity
STYK_RS02520	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
STYK_RS02525	COG0512	Glutamine amidotransferase of anthranilate synthase
STYK_RS02570	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
STYK_RS02580	COG3237	CsbD-like
STYK_RS02600	COG2261	transglycosylase associated protein
STYK_RS02780	COG1609	Transcriptional regulator
STYK_RS02805	COG0395	ABC-type sugar transport system, permease component
STYK_RS02810	COG1621	beta-fructofuranosidase activity
STYK_RS02820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
STYK_RS02835	COG1051	belongs to the nudix hydrolase family
STYK_RS02845	COG2264	protein methyltransferase activity
STYK_RS02850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
STYK_RS02855	COG1164	Oligoendopeptidase f
STYK_RS02865	COG1733	regulation of RNA biosynthetic process
STYK_RS02880	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
STYK_RS02895	COG0720	synthase
STYK_RS02905	COG3118	belongs to the thioredoxin family
STYK_RS02925	COG1346	cytolysis
STYK_RS02940	COG1132	(ABC) transporter
STYK_RS02945	COG0535	radical SAM domain protein
STYK_RS02960	COG1131	(ABC) transporter
STYK_RS02965	COG1725	Transcriptional regulator
STYK_RS02980	COG1484	DNA-dependent DNA replication
STYK_RS02985	COG0778	Nitroreductase
STYK_RS03010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
STYK_RS03015	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
STYK_RS03030	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
STYK_RS03045	COG3458	cephalosporin-C deacetylase activity
STYK_RS03060	COG1653	transport
STYK_RS03065	COG1175	transmembrane transport
STYK_RS03075	COG4409	exo-alpha-(2->6)-sialidase activity
STYK_RS03080	COG0673	inositol 2-dehydrogenase activity
STYK_RS03085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
STYK_RS03110	COG0768	penicillin binding
STYK_RS03125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STYK_RS03145	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
STYK_RS03185	COG0577	efflux transmembrane transporter activity
STYK_RS03185	COG1136	(ABC) transporter
STYK_RS03195	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
STYK_RS03215	COG3590	peptidase
STYK_RS03225	COG2247	cell wall binding repeat
STYK_RS03225	COG0860	N-Acetylmuramoyl-L-alanine amidase
STYK_RS03265	COG1959	2 iron, 2 sulfur cluster binding
STYK_RS03275	COG0745	RESPONSE REGULATOR receiver
STYK_RS03280	COG5002	protein histidine kinase activity
STYK_RS03305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
STYK_RS03325	COG0204	Acyl-transferase
STYK_RS03330	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
STYK_RS03335	COG2384	SAM-dependent methyltransferase
STYK_RS03340	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
STYK_RS03345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
STYK_RS03355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STYK_RS03360	COG0463	Glycosyl transferase, family 2
STYK_RS03380	COG2824	Alkylphosphonate utilization operon protein PhnA
STYK_RS03400	COG0351	phosphomethylpyrimidine kinase
STYK_RS03405	COG4720	Psort location CytoplasmicMembrane, score
STYK_RS03415	COG0006	proline dipeptidase activity
STYK_RS03420	COG3442	glutamine amidotransferase
STYK_RS03425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STYK_RS03430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STYK_RS03435	COG0513	Belongs to the DEAD box helicase family
STYK_RS03445	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
STYK_RS03450	COG1335	isochorismatase
STYK_RS03470	COG0577	efflux transmembrane transporter activity
STYK_RS03475	COG1136	(ABC) transporter
STYK_RS03480	COG0577	efflux transmembrane transporter activity
STYK_RS03490	COG0745	RESPONSE REGULATOR receiver
STYK_RS03495	COG5002	protein histidine kinase activity
STYK_RS03500	COG0191	fructose-bisphosphate aldolase activity
STYK_RS03505	COG4555	ABC transporter
STYK_RS03525	COG1404	Belongs to the peptidase S8 family
STYK_RS03540	COG1242	4 iron, 4 sulfur cluster binding
STYK_RS03545	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
STYK_RS03585	COG0828	Belongs to the bacterial ribosomal protein bS21 family
STYK_RS03610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
STYK_RS03620	COG0647	UMP catabolic process
STYK_RS03630	COG1393	Belongs to the ArsC family
STYK_RS03640	COG0483	inositol monophosphate 1-phosphatase activity
STYK_RS03645	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
STYK_RS03645	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
STYK_RS03650	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
STYK_RS03655	COG0573	inorganic phosphate transmembrane transporter activity
STYK_RS03660	COG0581	inorganic phosphate transmembrane transporter activity
STYK_RS03665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
STYK_RS03670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
STYK_RS03675	COG0704	Plays a role in the regulation of phosphate uptake
STYK_RS03680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STYK_RS03685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
STYK_RS03700	COG3527	Alpha-acetolactate decarboxylase
STYK_RS03715	COG3842	ATPase activity
STYK_RS03720	COG1177	transmembrane transport
STYK_RS03765	COG1131	(ABC) transporter
STYK_RS03775	COG1368	sulfuric ester hydrolase activity
STYK_RS03780	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
STYK_RS03805	COG0287	Prephenate dehydrogenase
STYK_RS03815	COG1704	LemA family
STYK_RS03830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
STYK_RS03835	COG0077	Prephenate dehydratase
STYK_RS03845	COG3475	LICD family
STYK_RS03855	COG1215	transferase activity, transferring glycosyl groups
STYK_RS03885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STYK_RS03885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STYK_RS03895	COG1132	(ABC) transporter
STYK_RS03900	COG0402	S-adenosylhomocysteine deaminase activity
STYK_RS03905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
STYK_RS03915	COG5504	Zn-dependent protease
STYK_RS03930	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
STYK_RS03935	COG0167	dihydroorotate dehydrogenase activity
STYK_RS03945	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
STYK_RS03950	COG4470	Protein conserved in bacteria
STYK_RS03955	COG0820	rRNA (adenine-C2-)-methyltransferase activity
STYK_RS03965	COG0488	(ABC) transporter
STYK_RS03970	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
STYK_RS04050	COG0697	spore germination
STYK_RS04060	COG2267	carboxylic ester hydrolase activity
STYK_RS04080	COG1328	CTP reductase activity
STYK_RS04080	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
STYK_RS04090	COG4443	Transcriptional Coactivator p15 (PC4)
STYK_RS04095	COG1268	BioY protein
STYK_RS04120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STYK_RS04125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
STYK_RS04130	COG1136	(ABC) transporter
STYK_RS04135	COG0577	efflux transmembrane transporter activity
STYK_RS04140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STYK_RS04140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STYK_RS04155	COG4989	oxidoreductase activity
STYK_RS04165	COG1028	Short-chain dehydrogenase reductase Sdr
STYK_RS04190	COG0745	RESPONSE REGULATOR receiver
STYK_RS04195	COG5002	protein histidine kinase activity
STYK_RS04215	COG0772	Belongs to the SEDS family
STYK_RS04220	COG0693	protein deglycase activity
STYK_RS04230	COG0187	DNA topoisomerase II activity
STYK_RS04250	COG0542	response to heat
STYK_RS04255	COG4703	Protein of unknown function (DUF1797)
STYK_RS04260	COG0765	amino acid transport
STYK_RS04265	COG1126	abc transporter atp-binding protein
STYK_RS04270	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
STYK_RS04280	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
STYK_RS04305	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
STYK_RS04315	COG0813	purine-nucleoside phosphorylase activity
STYK_RS04340	COG2813	Specifically methylates the guanine in position
STYK_RS04345	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
STYK_RS04355	COG0295	cytidine deaminase activity
STYK_RS04360	COG1744	ABC transporter substrate-binding protein PnrA-like
STYK_RS04365	COG3845	ABC transporter
STYK_RS04370	COG4603	Belongs to the binding-protein-dependent transport system permease family
STYK_RS04375	COG1079	Belongs to the binding-protein-dependent transport system permease family
STYK_RS04390	COG0187	DNA topoisomerase II activity
STYK_RS04405	COG2184	nucleotidyltransferase activity
STYK_RS04420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
STYK_RS04425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
STYK_RS04430	COG4166	transmembrane transport
STYK_RS04450	COG0539	negative regulation of cytoplasmic translation
STYK_RS04455	COG1956	GAF domain-containing protein
STYK_RS04460	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
STYK_RS04475	COG0719	Fe-S assembly protein
STYK_RS04480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
STYK_RS04490	COG0719	Fe-S assembly protein
STYK_RS04495	COG1686	Belongs to the peptidase S11 family
STYK_RS04500	COG0628	permease
STYK_RS04555	COG0583	DNA-binding transcription factor activity
STYK_RS04560	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
STYK_RS04565	COG0564	pseudouridine synthase activity
STYK_RS04570	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
STYK_RS04585	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
STYK_RS04595	COG0470	DNA polymerase III
STYK_RS04615	COG0528	UMP kinase activity
STYK_RS04625	COG2996	Protein conserved in bacteria
STYK_RS04630	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
STYK_RS04630	COG0456	acetyltransferase
STYK_RS04640	COG1702	phosphate starvation-inducible protein PhoH
STYK_RS04655	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
STYK_RS04655	COG3583	domain protein
STYK_RS04655	COG4932	domain protein
STYK_RS04660	COG0686	Belongs to the AlaDH PNT family
STYK_RS04665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
STYK_RS04670	COG1596	polysaccharide export
STYK_RS04670	COG1555	photosystem II stabilization
STYK_RS04675	COG2333	competence protein COMEC
STYK_RS04675	COG0658	competence protein
STYK_RS04700	COG0543	2 iron, 2 sulfur cluster binding
STYK_RS04705	COG0167	dihydroorotate dehydrogenase activity
STYK_RS04710	COG5263	repeat protein
STYK_RS04710	COG4193	domain, Protein
STYK_RS04715	COG1293	RNA-binding protein homologous to eukaryotic snRNP
STYK_RS04725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
STYK_RS04735	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
STYK_RS04740	COG0237	dephospho-CoA kinase activity
STYK_RS04745	COG2814	Major facilitator Superfamily
STYK_RS04750	COG0267	Belongs to the bacterial ribosomal protein bL33 family
STYK_RS04760	COG0557	exoribonuclease II activity
STYK_RS04770	COG0500	methyltransferase
STYK_RS04770	COG3615	Tellurite resistance protein tehB
STYK_RS04785	COG4122	O-methyltransferase activity
STYK_RS04795	COG0772	Belongs to the SEDS family
STYK_RS04800	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
STYK_RS04820	COG0358	DNA primase activity
STYK_RS04825	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
STYK_RS04830	COG2151	metal-sulfur cluster biosynthetic enzyme
STYK_RS04835	COG0438	transferase activity, transferring glycosyl groups
STYK_RS04840	COG0438	transferase activity, transferring glycosyl groups
STYK_RS04845	COG1983	PspC domain protein
STYK_RS04865	COG1438	arginine binding
STYK_RS04870	COG2936	dipeptidyl-peptidase activity
STYK_RS04890	COG0469	pyruvate kinase activity
STYK_RS04900	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
STYK_RS04905	COG3764	Sortase (surface protein transpeptidase)
STYK_RS04940	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
STYK_RS04965	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
STYK_RS04970	COG1438	arginine binding
STYK_RS04975	COG0497	DNA recombination
STYK_RS04980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
STYK_RS05000	COG3775	system Galactitol-specific IIC component
STYK_RS05025	COG3684	Belongs to the aldolase LacD family
STYK_RS05035	COG0698	ribose 5-phosphate isomerase
STYK_RS05045	COG1959	2 iron, 2 sulfur cluster binding
STYK_RS05050	COG0697	spore germination
STYK_RS05060	COG2226	methyltransferase
STYK_RS05070	COG3711	transcriptional antiterminator
STYK_RS05085	COG2723	6-phospho-beta-galactosidase activity
STYK_RS05100	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
STYK_RS05110	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
STYK_RS05115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
STYK_RS05135	COG2376	Dihydroxyacetone kinase
STYK_RS05140	COG1309	transcriptional regulator
STYK_RS05145	COG2376	Dihydroxyacetone kinase
STYK_RS05150	COG1461	Dihydroxyacetone kinase
STYK_RS05155	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
STYK_RS05160	COG1011	Hydrolase
STYK_RS05170	COG1051	belongs to the nudix hydrolase family
STYK_RS05175	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
STYK_RS05180	COG0534	Mate efflux family protein
STYK_RS05185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
STYK_RS05190	COG0022	dehydrogenase e1 component
STYK_RS05195	COG0508	dehydrogenase complex catalyzes the overall conversion of
STYK_RS05200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STYK_RS05205	COG0095	Lipoate-protein ligase
STYK_RS05215	COG0038	chloride channel
STYK_RS05225	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
STYK_RS05230	COG0438	transferase activity, transferring glycosyl groups
STYK_RS05250	COG1215	transferase activity, transferring glycosyl groups
STYK_RS05255	COG1216	Glycosyl transferase, family 2
STYK_RS05260	COG1215	transferase activity, transferring glycosyl groups
STYK_RS05265	COG1216	Glycosyl transferase, family 2
STYK_RS05275	COG0438	transferase activity, transferring glycosyl groups
STYK_RS05280	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
STYK_RS05295	COG0489	protein tyrosine kinase activity
STYK_RS05315	COG4464	protein tyrosine phosphatase activity
STYK_RS05340	COG0561	phosphatase activity
STYK_RS05345	COG1131	(ABC) transporter
STYK_RS05355	COG2205	protein histidine kinase activity
STYK_RS05360	COG0745	RESPONSE REGULATOR receiver
STYK_RS05365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
STYK_RS05385	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
STYK_RS05390	COG1982	Orn Lys Arg decarboxylase major
STYK_RS05415	COG0366	Alpha amylase catalytic
STYK_RS05420	COG0135	phosphoribosylanthranilate isomerase activity
STYK_RS05425	COG1597	lipid kinase activity
STYK_RS05495	COG0488	(ABC) transporter
STYK_RS05515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
STYK_RS05525	COG0741	lytic transglycosylase activity
STYK_RS05550	COG2890	protein-(glutamine-N5) methyltransferase activity
STYK_RS05555	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
STYK_RS05560	COG1435	thymidine kinase activity
STYK_RS05565	COG1942	4-Oxalocrotonate Tautomerase
STYK_RS05570	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
STYK_RS05580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
STYK_RS05595	COG4708	membrane
STYK_RS05605	COG1970	mechanosensitive ion channel activity
STYK_RS05615	COG2195	Cleaves the N-terminal amino acid of tripeptides
STYK_RS05630	COG0803	Belongs to the bacterial solute-binding protein 9 family
STYK_RS05630	COG3443	Belongs to the bacterial solute-binding protein 9 family
STYK_RS05635	COG0531	amino acid
STYK_RS05640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STYK_RS05645	COG0785	Cytochrome C biogenesis protein
STYK_RS05725	COG3299	homolog of phage Mu protein gp47
STYK_RS05845	COG5484	DNA packaging
STYK_RS06020	COG0582	viral genome integration into host DNA
STYK_RS06025	COG0776	regulation of translation
STYK_RS06030	COG1307	EDD domain protein, DegV family
STYK_RS06035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
STYK_RS06045	COG0024	Methionine aminopeptidase
STYK_RS06050	COG4109	DRTGG domain
STYK_RS06060	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
STYK_RS06080	COG0560	Phosphoserine phosphatase
STYK_RS06090	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
STYK_RS06100	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
STYK_RS06105	COG1012	belongs to the aldehyde dehydrogenase family
STYK_RS06110	COG1523	belongs to the glycosyl hydrolase 13 family
STYK_RS06130	COG0488	(ABC) transporter
STYK_RS06135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
STYK_RS06145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
STYK_RS06160	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
STYK_RS06170	COG0745	RESPONSE REGULATOR receiver
STYK_RS06175	COG1194	a g-specific adenine glycosylase
STYK_RS06180	COG0280	phosphate acetyltransferase
STYK_RS06185	COG0564	pseudouridine synthase activity
STYK_RS06195	COG2357	RelA SpoT domain protein
STYK_RS06205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
STYK_RS06210	COG1104	cysteine desulfurase activity
STYK_RS06230	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
STYK_RS06240	COG0210	DNA helicase
STYK_RS06250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
STYK_RS06255	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
STYK_RS06260	COG4684	Psort location CytoplasmicMembrane, score
STYK_RS06270	COG1827	regulation of RNA biosynthetic process
STYK_RS06280	COG1879	ABC-type sugar transport system periplasmic component
STYK_RS06285	COG1172	Belongs to the binding-protein-dependent transport system permease family
STYK_RS06295	COG1869	D-ribose catabolic process
STYK_RS06300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
STYK_RS06305	COG1609	Transcriptional regulator
STYK_RS06330	COG0556	nucleotide-excision repair
STYK_RS06340	COG0765	amino acid transport
STYK_RS06345	COG1126	abc transporter atp-binding protein
STYK_RS06350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
STYK_RS06355	COG0552	protein localization to endoplasmic reticulum
STYK_RS06360	COG0561	phosphatase activity
STYK_RS06365	COG0561	phosphatase activity
STYK_RS06380	COG0577	efflux transmembrane transporter activity
STYK_RS06385	COG1136	(ABC) transporter
STYK_RS06410	COG2183	response to ionizing radiation
STYK_RS06420	COG0701	Predicted permease
STYK_RS06425	COG3689	TIGRFAM TIGR03943 family protein
STYK_RS06430	COG0196	riboflavin kinase activity
STYK_RS06435	COG1196	nuclear chromosome segregation
STYK_RS06475	COG0473	3-isopropylmalate dehydrogenase activity
STYK_RS06490	COG3142	Participates in the control of copper homeostasis
STYK_RS06495	COG2832	Protein of unknown function (DUF454)
STYK_RS06505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
STYK_RS06515	COG0758	DNA mediated transformation
STYK_RS06520	COG4750	Nucleotidyl transferase
STYK_RS06535	COG1063	alcohol dehydrogenase
STYK_RS06550	COG3475	LICD family
STYK_RS06555	COG3475	LICD family
STYK_RS06565	COG0505	Belongs to the CarA family
STYK_RS06580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
STYK_RS06595	COG0488	(ABC) transporter
STYK_RS06605	COG1704	LemA family
STYK_RS06620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
STYK_RS06635	COG1078	dGTPase activity
STYK_RS06685	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
STYK_RS06690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
STYK_RS06695	COG0077	Prephenate dehydratase
STYK_RS06695	COG1605	Chorismate mutase
STYK_RS06700	COG0716	FMN binding
STYK_RS06705	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
STYK_RS06750	COG0584	glycerophosphoryl diester phosphodiesterase
STYK_RS06755	COG2176	DNA-directed DNA polymerase activity
STYK_RS06765	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
STYK_RS06775	COG0494	nUDIX hydrolase
STYK_RS06780	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
STYK_RS06795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
STYK_RS06830	COG1126	abc transporter atp-binding protein
STYK_RS06845	COG0628	permease
STYK_RS06850	COG4166	transmembrane transport
STYK_RS06855	COG2706	6-phosphogluconolactonase activity
STYK_RS06890	COG0356	it plays a direct role in the translocation of protons across the membrane
STYK_RS06900	COG0826	peptidase U32
STYK_RS06905	COG3064	Membrane
STYK_RS06920	COG2188	Transcriptional regulator
STYK_RS06925	COG0697	spore germination
STYK_RS06930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
STYK_RS06940	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
STYK_RS06965	COG1104	cysteine desulfurase activity
STYK_RS06975	COG1674	ftsk spoiiie
STYK_RS06975	COG0697	spore germination
STYK_RS06980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STYK_RS06980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STYK_RS06980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STYK_RS06985	COG1105	Belongs to the carbohydrate kinase PfkB family
STYK_RS06990	COG1349	DNA-binding transcription factor activity
STYK_RS07010	COG0561	phosphatase activity
STYK_RS07035	COG0492	ferredoxin-NADP+ reductase activity
STYK_RS07045	COG1126	abc transporter atp-binding protein
STYK_RS07055	COG1393	Belongs to the ArsC family
STYK_RS07060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
STYK_RS07075	COG1272	protein, Hemolysin III
STYK_RS07105	COG1053	succinate dehydrogenase
STYK_RS07105	COG0431	NADPH-dependent FMN reductase
STYK_RS07105	COG3976	FMN-binding domain protein
STYK_RS07130	COG0656	L-ascorbic acid biosynthetic process
STYK_RS07135	COG0726	polysaccharide deacetylase
STYK_RS07145	COG0513	Belongs to the DEAD box helicase family
STYK_RS07155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STYK_RS07155	COG2190	(PTS) system
STYK_RS07155	COG1263	PTS System
STYK_RS07160	COG2177	Part of the ABC transporter FtsEX involved in
STYK_RS07165	COG2884	Cell division ATP-binding protein ftsE
STYK_RS07175	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
STYK_RS07175	COG0617	tRNA 3'-terminal CCA addition
STYK_RS07175	COG0517	IMP dehydrogenase activity
STYK_RS07215	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
STYK_RS07220	COG2131	deaminase
STYK_RS07230	COG1307	EDD domain protein, DegV family
STYK_RS07235	COG2081	HI0933 family
STYK_RS07245	COG0789	Transcriptional regulator
STYK_RS07250	COG0733	neurotransmitter:sodium symporter activity
STYK_RS07255	COG1482	cell wall glycoprotein biosynthetic process
STYK_RS07260	COG2723	6-phospho-beta-galactosidase activity
STYK_RS07280	COG0028	Belongs to the TPP enzyme family
STYK_RS07285	COG2217	Heavy metal translocating P-type atpase
STYK_RS07305	COG0352	thiamine-phosphate diphosphorylase activity
STYK_RS07320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
STYK_RS07330	COG4172	Belongs to the ABC transporter superfamily
STYK_RS07365	COG0765	amino acid transport
STYK_RS07370	COG1126	abc transporter atp-binding protein
STYK_RS07375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STYK_RS07390	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
STYK_RS07410	COG1217	gtp-binding protein TYPA
STYK_RS07415	COG1187	pseudouridine synthase activity
STYK_RS07420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
STYK_RS07430	COG0583	DNA-binding transcription factor activity
STYK_RS07435	COG0300	oxidoreductase activity
STYK_RS07445	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
STYK_RS07450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
STYK_RS07470	COG1940	carbohydrate kinase activity
STYK_RS07500	COG2972	Histidine kinase
STYK_RS07505	COG2207	Transcriptional regulator
STYK_RS07505	COG4753	response regulator
STYK_RS07510	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STYK_RS07510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STYK_RS07515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STYK_RS07520	COG0785	Cytochrome C biogenesis protein
STYK_RS07535	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
STYK_RS07555	COG1131	(ABC) transporter
STYK_RS07565	COG1113	amino acid transport
STYK_RS07575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
STYK_RS07600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
STYK_RS07605	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
STYK_RS07610	COG0626	cystathionine gamma-synthase activity
STYK_RS07625	COG2244	polysaccharide biosynthetic process
STYK_RS07630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
STYK_RS07655	COG2827	Endonuclease containing a URI domain
STYK_RS07660	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
STYK_RS07665	COG1098	S1 RNA binding domain
STYK_RS07680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
STYK_RS07685	COG0629	single-stranded DNA binding
STYK_RS07690	COG0360	Binds together with S18 to 16S ribosomal RNA
STYK_RS07700	COG0017	Asparaginyl-tRNA synthetase
STYK_RS07710	COG0436	Aminotransferase
STYK_RS07735	COG3711	transcriptional antiterminator
STYK_RS07750	COG0242	peptide deformylase activity
STYK_RS07755	COG0625	glutathione transferase activity
STYK_RS07765	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
STYK_RS07770	COG0488	(ABC) transporter
STYK_RS07775	COG0617	tRNA 3'-terminal CCA addition
STYK_RS07785	COG1307	EDD domain protein, DegV family
STYK_RS07805	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
STYK_RS07810	COG0492	ferredoxin-NADP+ reductase activity
STYK_RS07820	COG0391	Required for morphogenesis under gluconeogenic growth conditions
STYK_RS07830	COG0251	oxidation-reduction process
STYK_RS07850	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
STYK_RS07860	COG4193	domain, Protein
STYK_RS07860	COG5263	repeat protein
STYK_RS07870	COG3935	DnaD domain protein
STYK_RS07890	COG2226	methyltransferase
STYK_RS07925	COG1363	Peptidase, m42
STYK_RS07930	COG1114	Component of the transport system for branched-chain amino acids
STYK_RS07945	COG1573	uracil-dna glycosylase
STYK_RS07950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
STYK_RS07965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STYK_RS08005	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
STYK_RS08005	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
STYK_RS08015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STYK_RS08020	COG0765	amino acid transport
STYK_RS08025	COG0765	amino acid transport
STYK_RS08035	COG3842	ATPase activity
STYK_RS08045	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
STYK_RS08050	COG0215	cysteine-tRNA ligase activity
STYK_RS08060	COG1045	serine acetyltransferase
STYK_RS08075	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
STYK_RS08080	COG3620	sequence-specific DNA binding
STYK_RS08125	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
STYK_RS08135	COG1940	carbohydrate kinase activity
STYK_RS08140	COG1263	PTS System
STYK_RS08140	COG2190	(PTS) system
STYK_RS08140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STYK_RS08145	COG1621	beta-fructofuranosidase activity
STYK_RS08150	COG1609	Transcriptional regulator
STYK_RS08160	COG3425	synthase
STYK_RS08175	COG0515	serine threonine protein kinase
STYK_RS08175	COG2815	serine threonine protein kinase
STYK_RS08180	COG0631	protein serine/threonine phosphatase activity
STYK_RS08185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
STYK_RS08185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
STYK_RS08195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
STYK_RS08205	COG0194	GDP metabolic process
STYK_RS08220	COG1323	Belongs to the UPF0348 family
STYK_RS08225	COG2226	methyltransferase
STYK_RS08230	COG0799	negative regulation of ribosome biogenesis
STYK_RS08240	COG1713	HD superfamily hydrolase involved in NAD metabolism
STYK_RS08245	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
STYK_RS08250	COG1534	Rna-binding protein
STYK_RS08255	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
STYK_RS08270	COG0668	transmembrane transport
STYK_RS08275	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
STYK_RS08285	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
STYK_RS08310	COG1063	alcohol dehydrogenase
STYK_RS08335	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
STYK_RS08340	COG0439	Biotin carboxylase
STYK_RS08355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
STYK_RS08360	COG1028	Short-chain dehydrogenase reductase Sdr
STYK_RS08365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
STYK_RS08375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
STYK_RS08390	COG1024	Enoyl-CoA hydratase
STYK_RS08395	COG0527	aspartate kinase activity
STYK_RS08420	COG1115	amino acid carrier protein
STYK_RS08425	COG3421	Type III restriction
STYK_RS08430	COG2189	Belongs to the N(4) N(6)-methyltransferase family
STYK_RS08455	COG0681	Belongs to the peptidase S26 family
STYK_RS08460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
STYK_RS08470	COG2197	response regulator
STYK_RS08475	COG4585	Histidine kinase
STYK_RS08520	COG0745	RESPONSE REGULATOR receiver
STYK_RS08525	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
STYK_RS08535	COG0116	Belongs to the methyltransferase superfamily
STYK_RS08560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STYK_RS08565	COG4166	transmembrane transport
STYK_RS08570	COG0562	UDP-galactopyranose mutase
STYK_RS08585	COG4166	transmembrane transport
STYK_RS08590	COG4166	transmembrane transport
STYK_RS08595	COG0366	Alpha amylase catalytic
STYK_RS08620	COG0768	penicillin binding
STYK_RS08625	COG4839	cell division protein FtsL
STYK_RS08670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
STYK_RS08675	COG3620	sequence-specific DNA binding
STYK_RS08695	COG1653	transport
STYK_RS08700	COG0395	ABC-type sugar transport system, permease component
STYK_RS08705	COG4209	transmembrane transport
STYK_RS08715	COG2169	Transcriptional regulator
STYK_RS08720	COG1373	ATPase (AAA superfamily
STYK_RS08740	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
STYK_RS08745	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
STYK_RS08750	COG1668	transmembrane transport
STYK_RS08755	COG4152	abc transporter atp-binding protein
STYK_RS08760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STYK_RS08760	COG0072	phenylalanine-tRNA ligase activity
STYK_RS08770	COG1247	-acetyltransferase
STYK_RS08780	COG0671	phosphoesterase, PA-phosphatase related
STYK_RS08785	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
STYK_RS08800	COG1122	ATPase activity
STYK_RS08815	COG0569	domain protein
STYK_RS08820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STYK_RS08840	COG1882	Formate acetyltransferase
STYK_RS08845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
STYK_RS08860	COG0765	amino acid transport
STYK_RS08875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
STYK_RS08885	COG0440	acetolactate synthase activity
STYK_RS08890	COG0028	Belongs to the TPP enzyme family
STYK_RS08895	COG1461	Dihydroxyacetone kinase
STYK_RS08905	COG0227	Belongs to the bacterial ribosomal protein bL28 family
STYK_RS08925	COG1132	(ABC) transporter
STYK_RS08965	COG1316	TRANSCRIPTIONal
STYK_RS08975	COG0802	atpase or kinase
STYK_RS09020	COG1674	ftsk spoiiie
STYK_RS09030	COG2946	Replication initiation factor
STYK_RS09060	COG0791	NLP P60 protein
STYK_RS09060	COG0741	lytic transglycosylase activity
STYK_RS09145	COG1523	belongs to the glycosyl hydrolase 13 family
STYK_RS09150	COG1126	abc transporter atp-binding protein
STYK_RS09155	COG0765	amino acid transport
STYK_RS09160	COG0765	amino acid transport
STYK_RS09165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STYK_RS09200	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
STYK_RS09205	COG3711	transcriptional antiterminator
STYK_RS09210	COG2213	PTS system mannitol-specific
STYK_RS09215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
STYK_RS09220	COG2723	6-phospho-beta-galactosidase activity
STYK_RS09230	COG0750	zinc metalloprotease
STYK_RS09235	COG4589	Belongs to the CDS family
STYK_RS09240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
STYK_RS09250	COG2255	four-way junction helicase activity
STYK_RS09275	COG3279	Response regulator of the LytR AlgR family
STYK_RS09305	COG2972	Histidine kinase
STYK_RS09310	COG2207	Transcriptional regulator
STYK_RS09310	COG4753	response regulator
STYK_RS09315	COG1840	ABC-type Fe3 transport system, periplasmic component
STYK_RS09320	COG1840	ABC-type Fe3 transport system, periplasmic component
STYK_RS09325	COG3842	ATPase activity
STYK_RS09330	COG1178	ABC-type Fe3 transport system permease component
STYK_RS09340	COG2848	UPF0210 protein
STYK_RS09345	COG3830	Belongs to the UPF0237 family
STYK_RS09355	COG0202	RNA polymerase activity
STYK_RS09360	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
STYK_RS09370	COG0257	Belongs to the bacterial ribosomal protein bL36 family
STYK_RS09375	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
STYK_RS09385	COG0201	protein transport
STYK_RS09400	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
STYK_RS09420	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
STYK_RS09440	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
STYK_RS09465	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
STYK_RS09495	COG0602	queuosine metabolic process
STYK_RS09520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
STYK_RS09530	COG0285	dihydrofolate synthase activity
STYK_RS09555	COG1393	Belongs to the ArsC family
STYK_RS09560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
STYK_RS09565	COG0006	proline dipeptidase activity
STYK_RS09570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
STYK_RS09600	COG0519	Catalyzes the synthesis of GMP from XMP
STYK_RS09625	COG1780	Probably involved in ribonucleotide reductase function
STYK_RS09635	COG2207	Transcriptional regulator
STYK_RS09635	COG4753	response regulator
STYK_RS09660	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
STYK_RS09665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
STYK_RS09670	COG1464	Belongs to the NlpA lipoprotein family
STYK_RS09675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STYK_RS09700	COG1214	PFAM Peptidase M22, glycoprotease
STYK_RS09720	COG0445	tRNA wobble uridine modification
STYK_RS09725	COG0494	nUDIX hydrolase
STYK_RS09730	COG0494	nUDIX hydrolase
STYK_RS09770	COG1705	Flagellar rod assembly protein muramidase FlgJ
STYK_RS09770	COG1388	LysM domain
STYK_RS09775	COG1760	l-serine dehydratase
STYK_RS09780	COG1760	l-serine dehydratase
STYK_RS09795	COG1216	Glycosyl transferase, family 2
STYK_RS09805	COG1695	Transcriptional regulator
STYK_RS09850	COG1653	transport
STYK_RS09855	COG0395	ABC-type sugar transport system, permease component
STYK_RS09860	COG4209	transmembrane transport
STYK_RS09875	COG0383	alpha-mannosidase activity
STYK_RS09895	COG3250	beta-galactosidase activity
STYK_RS09905	COG3443	Belongs to the bacterial solute-binding protein 9 family
STYK_RS09905	COG0803	Belongs to the bacterial solute-binding protein 9 family
STYK_RS09910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
STYK_RS09915	COG1121	(ABC) transporter
STYK_RS09920	COG1846	Transcriptional regulator
STYK_RS09925	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
STYK_RS09935	COG1696	Membrane protein involved in D-alanine export
STYK_RS09950	COG2211	Major facilitator Superfamily
STYK_RS09955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
STYK_RS09960	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
STYK_RS09980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
STYK_RS10000	COG3201	nicotinamide mononucleotide transporter
STYK_RS10005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
STYK_RS10010	COG0542	response to heat
STYK_RS10015	COG4463	regulation of RNA biosynthetic process
STYK_RS10020	COG1116	anion transmembrane transporter activity
STYK_RS10025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
STYK_RS10030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
STYK_RS10050	COG0305	Participates in initiation and elongation during chromosome replication
STYK_RS10070	COG1040	competence protein
STYK_RS10075	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
STYK_RS10080	COG1739	Uncharacterized protein family UPF0029
STYK_RS10100	COG3942	CHAP domain
STYK_RS10110	COG1792	Involved in formation and maintenance of cell shape
STYK_RS10115	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
STYK_RS10120	COG1122	ATPase activity
STYK_RS10125	COG1122	ATPase activity
STYK_RS10130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
STYK_RS10140	COG0612	Peptidase, M16
STYK_RS10145	COG0612	Peptidase, M16
STYK_RS10150	COG2501	S4 domain
STYK_RS10160	COG0516	GMP reductase activity
STYK_RS10160	COG0517	IMP dehydrogenase activity
STYK_RS10165	COG0180	Tryptophanyl-tRNA synthetase
STYK_RS10170	COG0488	(ABC) transporter
STYK_RS10180	COG1511	domain protein
STYK_RS10180	COG1511	domain protein
STYK_RS10225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
STYK_RS10230	COG1475	DNA binding