locus-tag	class	description
SRT_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SRT_RS00010	COG0592	DNA-directed DNA polymerase activity
SRT_RS00025	COG0012	GTP binding
SRT_RS00030	COG0193	aminoacyl-tRNA hydrolase activity
SRT_RS00040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SRT_RS00060	COG0037	tRNA processing
SRT_RS00065	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SRT_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SRT_RS00075	COG0531	amino acid
SRT_RS00185	COG1792	Involved in formation and maintenance of cell shape
SRT_RS00195	COG3942	CHAP domain
SRT_RS00205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SRT_RS00210	COG0436	Aminotransferase
SRT_RS00220	COG0416	fatty acid biosynthetic process
SRT_RS00225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRT_RS00260	COG1131	(ABC) transporter
SRT_RS00275	COG2274	protein secretion by the type I secretion system
SRT_RS00290	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SRT_RS00300	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SRT_RS00310	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SRT_RS00315	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SRT_RS00325	COG0138	bifunctional purine biosynthesis protein purh
SRT_RS00365	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SRT_RS00380	COG1794	racemase activity, acting on amino acids and derivatives
SRT_RS00395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SRT_RS00415	COG2255	four-way junction helicase activity
SRT_RS00420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SRT_RS00455	COG0534	Mate efflux family protein
SRT_RS00460	COG3830	Belongs to the UPF0237 family
SRT_RS00465	COG2848	UPF0210 protein
SRT_RS00480	COG1705	Flagellar rod assembly protein muramidase FlgJ
SRT_RS00495	COG1420	regulation of RNA biosynthetic process
SRT_RS00500	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SRT_RS00510	COG0443	Heat shock 70 kDa protein
SRT_RS00520	COG0101	tRNA pseudouridine synthase activity
SRT_RS00525	COG0351	phosphomethylpyrimidine kinase
SRT_RS00535	COG4475	Protein of unknown function (DUF436)
SRT_RS00540	COG0668	transmembrane transport
SRT_RS00560	COG1132	(ABC) transporter
SRT_RS00570	COG1129	ABC transporter
SRT_RS00575	COG1131	(ABC) transporter
SRT_RS00600	COG3343	RNA polymerase activity
SRT_RS00605	COG0504	CTP synthase activity
SRT_RS00650	COG1396	sequence-specific DNA binding
SRT_RS00665	COG1105	Belongs to the carbohydrate kinase PfkB family
SRT_RS00670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SRT_RS00670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SRT_RS00670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SRT_RS00675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SRT_RS00675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SRT_RS00675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SRT_RS00680	COG3684	Belongs to the aldolase LacD family
SRT_RS00705	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SRT_RS00710	COG0534	Mate efflux family protein
SRT_RS00715	COG2176	DNA-directed DNA polymerase activity
SRT_RS00720	COG1846	Transcriptional regulator
SRT_RS00725	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SRT_RS00730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SRT_RS00735	COG0508	dehydrogenase complex catalyzes the overall conversion of
SRT_RS00735	COG0022	dehydrogenase e1 component
SRT_RS00750	COG0095	Lipoate-protein ligase
SRT_RS00755	COG1473	amidohydrolase
SRT_RS00760	COG0477	Major facilitator Superfamily
SRT_RS00770	COG0583	DNA-binding transcription factor activity
SRT_RS00780	COG0281	malic enzyme
SRT_RS00785	COG0679	Auxin Efflux Carrier
SRT_RS00790	COG2140	Oxalate decarboxylase
SRT_RS00805	COG0242	peptide deformylase activity
SRT_RS00810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SRT_RS00820	COG1454	alcohol dehydrogenase
SRT_RS00820	COG1012	belongs to the aldehyde dehydrogenase family
SRT_RS00830	COG0300	oxidoreductase activity
SRT_RS00855	COG1045	serine acetyltransferase
SRT_RS00860	COG0215	cysteine-tRNA ligase activity
SRT_RS00865	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SRT_RS00880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SRT_RS00900	COG1476	TRANSCRIPTIONal
SRT_RS00910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SRT_RS00935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SRT_RS00945	COG0431	NADPH-dependent FMN reductase
SRT_RS00945	COG3976	FMN-binding domain protein
SRT_RS00945	COG1053	succinate dehydrogenase
SRT_RS00950	COG3976	FMN-binding domain protein
SRT_RS00950	COG1053	succinate dehydrogenase
SRT_RS00950	COG0431	NADPH-dependent FMN reductase
SRT_RS00970	COG0803	Belongs to the bacterial solute-binding protein 9 family
SRT_RS00985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SRT_RS00990	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SRT_RS01040	COG1121	(ABC) transporter
SRT_RS01045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SRT_RS01050	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SRT_RS01055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SRT_RS01060	COG0085	RNA polymerase activity
SRT_RS01065	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SRT_RS01080	COG1459	type II secretion system
SRT_RS01115	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SRT_RS01135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SRT_RS01150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SRT_RS01155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SRT_RS01185	COG2197	response regulator
SRT_RS01210	COG3715	PTS system
SRT_RS01215	COG3716	PTS system mannose fructose sorbose family IID component
SRT_RS01225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SRT_RS01230	COG0459	protein refolding
SRT_RS01245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SRT_RS01275	COG0495	leucyl-tRNA aminoacylation
SRT_RS01295	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SRT_RS01305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SRT_RS01315	COG4720	Psort location CytoplasmicMembrane, score
SRT_RS01320	COG1122	ATPase activity
SRT_RS01330	COG0357	Ribosomal RNA small subunit methyltransferase G
SRT_RS01335	COG1704	LemA family
SRT_RS01340	COG0501	Belongs to the peptidase M48B family
SRT_RS01350	COG1136	(ABC) transporter
SRT_RS01370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SRT_RS01380	COG1484	DNA-dependent DNA replication
SRT_RS01385	COG1160	GTP binding
SRT_RS01395	COG0586	Pfam SNARE associated Golgi protein
SRT_RS01405	COG3290	protein histidine kinase activity
SRT_RS01460	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SRT_RS01490	COG3716	PTS system mannose fructose sorbose family IID component
SRT_RS01495	COG3715	PTS system
SRT_RS01510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SRT_RS01520	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SRT_RS01535	COG1193	negative regulation of DNA recombination
SRT_RS01540	COG3118	belongs to the thioredoxin family
SRT_RS01545	COG1063	alcohol dehydrogenase
SRT_RS01550	COG1194	a g-specific adenine glycosylase
SRT_RS01560	COG0360	Binds together with S18 to 16S ribosomal RNA
SRT_RS01565	COG0629	single-stranded DNA binding
SRT_RS01570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SRT_RS01610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SRT_RS01615	COG0006	proline dipeptidase activity
SRT_RS01620	COG2131	deaminase
SRT_RS01630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SRT_RS01645	COG1609	Transcriptional regulator
SRT_RS01650	COG1621	beta-fructofuranosidase activity
SRT_RS01660	COG1940	carbohydrate kinase activity
SRT_RS01665	COG1482	cell wall glycoprotein biosynthetic process
SRT_RS01670	COG0653	protein targeting
SRT_RS01675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SRT_RS01680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SRT_RS01690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SRT_RS01695	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SRT_RS01705	COG0252	asparaginase activity
SRT_RS01710	COG0561	phosphatase activity
SRT_RS01720	COG1268	BioY protein
SRT_RS01725	COG0436	Aminotransferase
SRT_RS01730	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SRT_RS01735	COG1335	isochorismatase
SRT_RS01740	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SRT_RS01745	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SRT_RS01750	COG0154	amidase activity
SRT_RS01755	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SRT_RS01765	COG1819	glycosyl
SRT_RS01785	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SRT_RS01790	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SRT_RS01795	COG1534	Rna-binding protein
SRT_RS01800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SRT_RS01805	COG1713	HD superfamily hydrolase involved in NAD metabolism
SRT_RS01810	COG0799	negative regulation of ribosome biogenesis
SRT_RS01815	COG2226	methyltransferase
SRT_RS01830	COG1323	Belongs to the UPF0348 family
SRT_RS01845	COG0789	Transcriptional regulator
SRT_RS01850	COG0217	transcriptional regulatory protein
SRT_RS01860	COG1862	Preprotein translocase
SRT_RS01870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SRT_RS01875	COG4589	Belongs to the CDS family
SRT_RS01885	COG0442	prolyl-tRNA aminoacylation
SRT_RS01940	COG3557	Belongs to the UPF0374 family
SRT_RS01950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SRT_RS01955	COG1780	Probably involved in ribonucleotide reductase function
SRT_RS01995	COG0519	Catalyzes the synthesis of GMP from XMP
SRT_RS02010	COG0525	valine-tRNA ligase activity
SRT_RS02095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SRT_RS02100	COG1024	Enoyl-CoA hydratase
SRT_RS02105	COG1846	Transcriptional regulator
SRT_RS02125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SRT_RS02130	COG1028	Short-chain dehydrogenase reductase Sdr
SRT_RS02135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SRT_RS02150	COG0439	Biotin carboxylase
SRT_RS02165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SRT_RS02175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SRT_RS02190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SRT_RS02195	COG0706	membrane insertase activity
SRT_RS02200	COG1254	Belongs to the acylphosphatase family
SRT_RS02205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SRT_RS02225	COG3763	UPF0154 protein
SRT_RS02230	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SRT_RS02235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SRT_RS02250	COG0582	viral genome integration into host DNA
SRT_RS02255	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SRT_RS02260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SRT_RS02265	COG1187	pseudouridine synthase activity
SRT_RS02270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SRT_RS02275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SRT_RS02280	COG0569	domain protein
SRT_RS02305	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SRT_RS02310	COG0671	phosphoesterase, PA-phosphatase related
SRT_RS02325	COG1242	4 iron, 4 sulfur cluster binding
SRT_RS02330	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SRT_RS02340	COG0025	NhaP-type Na H and K H
SRT_RS02345	COG1119	ATPase activity
SRT_RS02350	COG0628	permease
SRT_RS02355	COG1253	flavin adenine dinucleotide binding
SRT_RS02360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SRT_RS02370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRT_RS02380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRT_RS02400	COG2378	regulation of single-species biofilm formation
SRT_RS02405	COG0693	protein deglycase activity
SRT_RS02425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRT_RS02430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRT_RS02440	COG1120	ATPase activity
SRT_RS02450	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SRT_RS02455	COG2244	polysaccharide biosynthetic process
SRT_RS02460	COG0626	cystathionine gamma-synthase activity
SRT_RS02465	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SRT_RS02475	COG0740	serine-type endopeptidase activity
SRT_RS02485	COG4471	UPF0298 protein
SRT_RS02495	COG0559	Belongs to the binding-protein-dependent transport system permease family
SRT_RS02515	COG0517	IMP dehydrogenase activity
SRT_RS02530	COG1774	PSP1 C-terminal conserved region
SRT_RS02535	COG4467	Involved in initiation control of chromosome replication
SRT_RS02545	COG0004	ammonium transporteR
SRT_RS02550	COG0347	Belongs to the P(II) protein family
SRT_RS02555	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SRT_RS02565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SRT_RS02570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SRT_RS02575	COG1393	Belongs to the ArsC family
SRT_RS02580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SRT_RS02585	COG0708	Exodeoxyribonuclease III
SRT_RS02595	COG0640	Transcriptional regulator
SRT_RS02625	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SRT_RS02650	COG1674	ftsk spoiiie
SRT_RS02660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SRT_RS02665	COG0081	regulation of translation
SRT_RS02670	COG0528	UMP kinase activity
SRT_RS02675	COG0233	cytoplasmic translational termination
SRT_RS02685	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SRT_RS02690	COG4479	Belongs to the UPF0346 family
SRT_RS02695	COG1702	phosphate starvation-inducible protein PhoH
SRT_RS02705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SRT_RS02710	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SRT_RS02730	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SRT_RS02735	COG0237	dephospho-CoA kinase activity
SRT_RS02755	COG0557	exoribonuclease II activity
SRT_RS02760	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SRT_RS02775	COG0346	lactoylglutathione lyase activity
SRT_RS02785	COG1940	carbohydrate kinase activity
SRT_RS02800	COG1609	Transcriptional regulator
SRT_RS02825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SRT_RS02840	COG1956	GAF domain-containing protein
SRT_RS02845	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SRT_RS02885	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SRT_RS02890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SRT_RS02895	COG3842	ATPase activity
SRT_RS02900	COG3833	ABC-type maltose transport systems, permease component
SRT_RS02905	COG1175	transmembrane transport
SRT_RS02920	COG1609	Transcriptional regulator
SRT_RS02925	COG1640	4-alpha-glucanotransferase
SRT_RS02930	COG0058	SHG alpha-glucan phosphorylase activity
SRT_RS02935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SRT_RS02940	COG0569	domain protein
SRT_RS02960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SRT_RS02970	COG4109	DRTGG domain
SRT_RS02980	COG1295	ribonuclease BN
SRT_RS02990	COG1131	(ABC) transporter
SRT_RS03000	COG4585	Histidine kinase
SRT_RS03005	COG2197	response regulator
SRT_RS03015	COG4708	membrane
SRT_RS03020	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SRT_RS03025	COG1597	lipid kinase activity
SRT_RS03030	COG1523	belongs to the glycosyl hydrolase 13 family
SRT_RS03035	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SRT_RS03040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SRT_RS03045	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SRT_RS03050	COG0297	glycogen (starch) synthase activity
SRT_RS03055	COG0058	SHG alpha-glucan phosphorylase activity
SRT_RS03065	COG0356	it plays a direct role in the translocation of protons across the membrane
SRT_RS03070	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SRT_RS03075	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SRT_RS03080	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SRT_RS03085	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SRT_RS03090	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SRT_RS03095	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SRT_RS03105	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SRT_RS03120	COG0765	amino acid transport
SRT_RS03135	COG1126	abc transporter atp-binding protein
SRT_RS03140	COG0745	RESPONSE REGULATOR receiver
SRT_RS03145	COG5002	protein histidine kinase activity
SRT_RS03155	COG0571	ribonuclease III activity
SRT_RS03160	COG1196	nuclear chromosome segregation
SRT_RS03165	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SRT_RS03220	COG1857	crispr-associated protein
SRT_RS03235	COG1518	maintenance of DNA repeat elements
SRT_RS03245	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SRT_RS03250	COG1074	ATP-dependent DNA helicase activity
SRT_RS03255	COG1349	DNA-binding transcription factor activity
SRT_RS03260	COG0698	ribose 5-phosphate isomerase
SRT_RS03265	COG0698	ribose 5-phosphate isomerase
SRT_RS03270	COG1105	Belongs to the carbohydrate kinase PfkB family
SRT_RS03275	COG3684	Belongs to the aldolase LacD family
SRT_RS03280	COG1447	Phosphotransferase system cellobiose-specific component IIA
SRT_RS03285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SRT_RS03285	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SRT_RS03290	COG2723	6-phospho-beta-galactosidase activity
SRT_RS03340	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SRT_RS03345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SRT_RS03355	COG1234	tRNA 3'-trailer cleavage
SRT_RS03360	COG0300	oxidoreductase activity
SRT_RS03365	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SRT_RS03365	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SRT_RS03370	COG2378	regulation of single-species biofilm formation
SRT_RS03385	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SRT_RS03390	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SRT_RS03400	COG2384	SAM-dependent methyltransferase
SRT_RS03410	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SRT_RS03425	COG1088	dTDP-glucose 4,6-dehydratase activity
SRT_RS03435	COG0628	permease
SRT_RS03445	COG0028	Belongs to the TPP enzyme family
SRT_RS03450	COG3527	Alpha-acetolactate decarboxylase
SRT_RS03455	COG1113	amino acid transport
SRT_RS03475	COG1122	ATPase activity
SRT_RS03505	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SRT_RS03520	COG1215	transferase activity, transferring glycosyl groups
SRT_RS03530	COG0488	(ABC) transporter
SRT_RS03540	COG3442	glutamine amidotransferase
SRT_RS03545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SRT_RS03550	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SRT_RS03560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SRT_RS03565	COG2249	NAD(P)H dehydrogenase (quinone) activity
SRT_RS03575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SRT_RS03585	COG1051	belongs to the nudix hydrolase family
SRT_RS03590	COG0647	UMP catabolic process
SRT_RS03600	COG1136	(ABC) transporter
SRT_RS03600	COG0577	efflux transmembrane transporter activity
SRT_RS03610	COG1053	succinate dehydrogenase
SRT_RS03610	COG3976	FMN-binding domain protein
SRT_RS03630	COG1518	maintenance of DNA repeat elements
SRT_RS03655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SRT_RS03700	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
SRT_RS03710	COG0673	inositol 2-dehydrogenase activity
SRT_RS03720	COG0572	uridine kinase
SRT_RS03730	COG0473	3-isopropylmalate dehydrogenase activity
SRT_RS03735	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SRT_RS03740	COG0066	3-isopropylmalate dehydratase activity
SRT_RS03755	COG0456	acetyltransferase
SRT_RS03755	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SRT_RS03765	COG2813	Specifically methylates the guanine in position
SRT_RS03770	COG3340	Belongs to the peptidase S51 family
SRT_RS03775	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SRT_RS03785	COG2884	Cell division ATP-binding protein ftsE
SRT_RS03820	COG1199	ATP-dependent helicase activity
SRT_RS03820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SRT_RS03825	COG0436	Aminotransferase
SRT_RS03830	COG0017	Asparaginyl-tRNA synthetase
SRT_RS03840	COG0371	Dehydrogenase
SRT_RS03845	COG0251	oxidation-reduction process
SRT_RS03855	COG1660	Displays ATPase and GTPase activities
SRT_RS03880	COG2226	methyltransferase
SRT_RS03900	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SRT_RS03905	COG0625	glutathione transferase activity
SRT_RS03910	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SRT_RS03915	COG0716	FMN binding
SRT_RS03930	COG0077	Prephenate dehydratase
SRT_RS03930	COG1605	Chorismate mutase
SRT_RS03935	COG0038	chloride channel
SRT_RS03940	COG0038	chloride channel
SRT_RS03945	COG0335	large ribosomal subunit rRNA binding
SRT_RS03955	COG2814	Major facilitator Superfamily
SRT_RS03980	COG0772	Belongs to the SEDS family
SRT_RS03995	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SRT_RS04010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SRT_RS04015	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SRT_RS04020	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SRT_RS04025	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SRT_RS04030	COG0560	Phosphoserine phosphatase
SRT_RS04035	COG0131	Imidazoleglycerol-phosphate dehydratase
SRT_RS04045	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SRT_RS04050	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SRT_RS04055	COG0107	imidazoleglycerol-phosphate synthase activity
SRT_RS04060	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SRT_RS04145	COG1011	Hydrolase
SRT_RS04155	COG0322	excinuclease ABC activity
SRT_RS04165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SRT_RS04170	COG1573	uracil-dna glycosylase
SRT_RS04190	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SRT_RS04195	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SRT_RS04200	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SRT_RS04225	COG0813	purine-nucleoside phosphorylase activity
SRT_RS04240	COG0543	2 iron, 2 sulfur cluster binding
SRT_RS04245	COG0167	dihydroorotate dehydrogenase activity
SRT_RS04250	COG0284	orotidine-5'-phosphate decarboxylase activity
SRT_RS04255	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SRT_RS04265	COG1881	PFAM PEBP family protein
SRT_RS04270	COG2315	Protein conserved in bacteria
SRT_RS04285	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SRT_RS04295	COG0737	Belongs to the 5'-nucleotidase family
SRT_RS04300	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SRT_RS04305	COG0187	DNA topoisomerase II activity
SRT_RS04310	COG2184	nucleotidyltransferase activity
SRT_RS04320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SRT_RS04340	COG0539	negative regulation of cytoplasmic translation
SRT_RS04370	COG1131	(ABC) transporter
SRT_RS04375	COG1725	Transcriptional regulator
SRT_RS04385	COG0205	6-phosphofructokinase activity
SRT_RS04390	COG0469	pyruvate kinase activity
SRT_RS04395	COG2261	transglycosylase associated protein
SRT_RS04405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SRT_RS04410	COG2213	PTS system mannitol-specific
SRT_RS04415	COG3711	transcriptional antiterminator
SRT_RS04420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SRT_RS04425	COG0246	Mannitol dehydrogenase
SRT_RS04430	COG2824	Alkylphosphonate utilization operon protein PhnA
SRT_RS04435	COG0765	amino acid transport
SRT_RS04440	COG1126	abc transporter atp-binding protein
SRT_RS04445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SRT_RS04450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SRT_RS04455	COG1115	amino acid carrier protein
SRT_RS04460	COG0210	DNA helicase
SRT_RS04465	COG2873	o-acetylhomoserine
SRT_RS04480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SRT_RS04495	COG0577	efflux transmembrane transporter activity
SRT_RS04505	COG2375	cellular response to nickel ion
SRT_RS04505	COG1132	(ABC) transporter
SRT_RS04510	COG1132	(ABC) transporter
SRT_RS04580	COG0745	RESPONSE REGULATOR receiver
SRT_RS04600	COG0196	riboflavin kinase activity
SRT_RS04605	COG1393	Belongs to the ArsC family
SRT_RS04615	COG0483	inositol monophosphate 1-phosphatase activity
SRT_RS04620	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SRT_RS04620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SRT_RS04630	COG0573	inorganic phosphate transmembrane transporter activity
SRT_RS04640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SRT_RS04645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SRT_RS04650	COG0704	Plays a role in the regulation of phosphate uptake
SRT_RS04665	COG0745	RESPONSE REGULATOR receiver
SRT_RS04680	COG1072	(Pantothenic acid kinase))
SRT_RS04685	COG2813	Specifically methylates the guanine in position
SRT_RS04690	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SRT_RS04695	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SRT_RS04700	COG0295	cytidine deaminase activity
SRT_RS04710	COG3845	ABC transporter
SRT_RS04715	COG4603	Belongs to the binding-protein-dependent transport system permease family
SRT_RS04720	COG1079	Belongs to the binding-protein-dependent transport system permease family
SRT_RS04735	COG0039	L-malate dehydrogenase activity
SRT_RS04745	COG3764	Sortase (surface protein transpeptidase)
SRT_RS04750	COG0346	lactoylglutathione lyase activity
SRT_RS04805	COG1174	glycine betaine transport
SRT_RS04810	COG1136	(ABC) transporter
SRT_RS04815	COG0577	efflux transmembrane transporter activity
SRT_RS04825	COG0431	NADPH-dependent FMN reductase
SRT_RS04825	COG3976	FMN-binding domain protein
SRT_RS04825	COG1053	succinate dehydrogenase
SRT_RS04840	COG1942	4-Oxalocrotonate Tautomerase
SRT_RS04845	COG1435	thymidine kinase activity
SRT_RS04850	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SRT_RS04855	COG2890	protein-(glutamine-N5) methyltransferase activity
SRT_RS04860	COG0009	L-threonylcarbamoyladenylate synthase
SRT_RS04885	COG1132	(ABC) transporter
SRT_RS04890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SRT_RS04895	COG4684	Psort location CytoplasmicMembrane, score
SRT_RS04900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SRT_RS04910	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SRT_RS04915	COG1247	-acetyltransferase
SRT_RS04930	COG0519	Catalyzes the synthesis of GMP from XMP
SRT_RS04935	COG2188	Transcriptional regulator
SRT_RS04945	COG3448	diguanylate cyclase activity
SRT_RS04945	COG4175	Glycine betaine
SRT_RS04955	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SRT_RS04960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SRT_RS04990	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SRT_RS04995	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SRT_RS05015	COG1104	cysteine desulfurase activity
SRT_RS05020	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SRT_RS05025	COG4116	CYTH
SRT_RS05035	COG2357	RelA SpoT domain protein
SRT_RS05040	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SRT_RS05045	COG0564	pseudouridine synthase activity
SRT_RS05050	COG0280	phosphate acetyltransferase
SRT_RS05060	COG1131	(ABC) transporter
SRT_RS05065	COG4221	oxidoreductase activity
SRT_RS05070	COG1442	glycosyl transferase family 8
SRT_RS05095	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SRT_RS05105	COG0745	RESPONSE REGULATOR receiver
SRT_RS05120	COG1131	(ABC) transporter
SRT_RS05125	COG4974	Belongs to the 'phage' integrase family
SRT_RS05160	COG3052	prosthetic group binding
SRT_RS05170	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
SRT_RS05175	COG0511	ligase activity, forming carbon-carbon bonds
SRT_RS05185	COG2851	Citrate transporter
SRT_RS05195	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
SRT_RS05200	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
SRT_RS05210	COG0745	RESPONSE REGULATOR receiver
SRT_RS05220	COG1136	(ABC) transporter
SRT_RS05225	COG5263	repeat protein
SRT_RS05225	COG0366	Alpha amylase catalytic
SRT_RS05230	COG5263	repeat protein
SRT_RS05230	COG0366	Alpha amylase catalytic
SRT_RS05235	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SRT_RS05240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SRT_RS05250	COG1940	carbohydrate kinase activity
SRT_RS05255	COG0110	maltose O-acetyltransferase activity
SRT_RS05270	COG4604	ABC transporter, ATP-binding protein
SRT_RS05275	COG4605	iron ion homeostasis
SRT_RS05280	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SRT_RS05285	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SRT_RS05290	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SRT_RS05340	COG0300	oxidoreductase activity
SRT_RS05340	COG4221	oxidoreductase activity
SRT_RS05340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRT_RS05340	COG3321	synthase
SRT_RS05345	COG1024	Enoyl-CoA hydratase
SRT_RS05350	COG4221	oxidoreductase activity
SRT_RS05350	COG0300	oxidoreductase activity
SRT_RS05350	COG3321	synthase
SRT_RS05350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRT_RS05365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRT_RS05365	COG1028	Short-chain dehydrogenase reductase Sdr
SRT_RS05365	COG4221	oxidoreductase activity
SRT_RS05365	COG3321	synthase
SRT_RS05370	COG3321	synthase
SRT_RS05370	COG1028	Short-chain dehydrogenase reductase Sdr
SRT_RS05370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRT_RS05370	COG0318	PFAM AMP-dependent synthetase and ligase
SRT_RS05370	COG0300	oxidoreductase activity
SRT_RS05380	COG0300	oxidoreductase activity
SRT_RS05380	COG4221	oxidoreductase activity
SRT_RS05380	COG3321	synthase
SRT_RS05380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRT_RS05390	COG1024	Enoyl-CoA hydratase
SRT_RS05405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SRT_RS05440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SRT_RS05445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SRT_RS05460	COG4932	domain protein
SRT_RS05490	COG3711	transcriptional antiterminator
SRT_RS05505	COG1176	ABC-type spermidine putrescine transport system, permease component I
SRT_RS05510	COG3842	ATPase activity
SRT_RS05515	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SRT_RS05535	COG0302	gtp cyclohydrolase
SRT_RS05540	COG0285	dihydrofolate synthase activity
SRT_RS05545	COG0083	homoserine kinase activity
SRT_RS05555	COG0726	polysaccharide deacetylase
SRT_RS05560	COG1960	acyl-CoA dehydrogenase activity
SRT_RS05575	COG0222	ribosome binding
SRT_RS05580	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SRT_RS05605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SRT_RS05610	COG2040	homocysteine
SRT_RS05615	COG0833	amino acid
SRT_RS05620	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SRT_RS05635	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SRT_RS05640	COG3201	nicotinamide mononucleotide transporter
SRT_RS05645	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SRT_RS05650	COG3425	synthase
SRT_RS05665	COG1272	protein, Hemolysin III
SRT_RS05670	COG1304	FMN binding
SRT_RS05690	COG0435	Glutathione S-transferase
SRT_RS05695	COG0456	acetyltransferase
SRT_RS05700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SRT_RS05705	COG1126	abc transporter atp-binding protein
SRT_RS05710	COG0765	amino acid transport
SRT_RS05715	COG0765	amino acid transport
SRT_RS05730	COG0583	DNA-binding transcription factor activity
SRT_RS05735	COG3759	membrane
SRT_RS05745	COG0745	RESPONSE REGULATOR receiver
SRT_RS05750	COG2357	RelA SpoT domain protein
SRT_RS05760	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SRT_RS05765	COG1132	(ABC) transporter
SRT_RS05780	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SRT_RS05795	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SRT_RS05805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SRT_RS05815	COG0366	Alpha amylase catalytic
SRT_RS05815	COG5263	repeat protein
SRT_RS05865	COG0583	DNA-binding transcription factor activity
SRT_RS05875	COG0656	L-ascorbic acid biosynthetic process
SRT_RS05880	COG0583	DNA-binding transcription factor activity
SRT_RS05885	COG0561	phosphatase activity
SRT_RS05925	COG2249	NAD(P)H dehydrogenase (quinone) activity
SRT_RS05935	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SRT_RS05960	COG0656	L-ascorbic acid biosynthetic process
SRT_RS05970	COG0583	DNA-binding transcription factor activity
SRT_RS05995	COG1063	alcohol dehydrogenase
SRT_RS06010	COG0667	Aldo Keto reductase
SRT_RS06045	COG0300	oxidoreductase activity
SRT_RS06060	COG1132	(ABC) transporter
SRT_RS06070	COG0454	-acetyltransferase
SRT_RS06080	COG0617	tRNA 3'-terminal CCA addition
SRT_RS06085	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SRT_RS06090	COG1307	EDD domain protein, DegV family
SRT_RS06140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SRT_RS06145	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SRT_RS06150	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SRT_RS06155	COG1609	Transcriptional regulator
SRT_RS06160	COG0366	Alpha amylase catalytic
SRT_RS06170	COG0366	Alpha amylase catalytic
SRT_RS06175	COG0395	ABC-type sugar transport system, permease component
SRT_RS06180	COG1175	transmembrane transport
SRT_RS06185	COG1653	transport
SRT_RS06190	COG3345	alpha-galactosidase
SRT_RS06195	COG2207	Transcriptional regulator
SRT_RS06200	COG0646	methionine synthase
SRT_RS06200	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SRT_RS06210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SRT_RS06210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SRT_RS06210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SRT_RS06215	COG1105	Belongs to the carbohydrate kinase PfkB family
SRT_RS06225	COG0492	ferredoxin-NADP+ reductase activity
SRT_RS06230	COG0336	Belongs to the RNA methyltransferase TrmD family
SRT_RS06240	COG1837	Belongs to the UPF0109 family
SRT_RS06245	COG0228	four-way junction DNA binding
SRT_RS06250	COG0577	efflux transmembrane transporter activity
SRT_RS06255	COG1136	(ABC) transporter
SRT_RS06265	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SRT_RS06270	COG0505	Belongs to the CarA family
SRT_RS06275	COG0540	Belongs to the ATCase OTCase family
SRT_RS06285	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SRT_RS06295	COG0564	pseudouridine synthase activity
SRT_RS06300	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SRT_RS06305	COG0583	DNA-binding transcription factor activity
SRT_RS06310	COG2816	NAD+ diphosphatase activity
SRT_RS06320	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SRT_RS06330	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SRT_RS06335	COG0301	tRNA thio-modification
SRT_RS06340	COG1104	cysteine desulfurase activity
SRT_RS06350	COG0285	dihydrofolate synthase activity
SRT_RS06355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SRT_RS06360	COG0656	L-ascorbic acid biosynthetic process
SRT_RS06365	COG3942	CHAP domain
SRT_RS06380	COG0463	Glycosyl transferase, family 2
SRT_RS06390	COG1368	sulfuric ester hydrolase activity
SRT_RS06430	COG1091	dTDP-4-dehydrorhamnose reductase activity
SRT_RS06440	COG2151	metal-sulfur cluster biosynthetic enzyme
SRT_RS06445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SRT_RS06450	COG0358	DNA primase activity
SRT_RS06460	COG1970	mechanosensitive ion channel activity
SRT_RS06470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SRT_RS06500	COG0556	nucleotide-excision repair
SRT_RS06515	COG1126	abc transporter atp-binding protein
SRT_RS06525	COG0488	(ABC) transporter
SRT_RS06535	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SRT_RS06580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SRT_RS06590	COG0077	Prephenate dehydratase
SRT_RS06595	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SRT_RS06600	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SRT_RS06605	COG3679	Belongs to the UPF0342 family
SRT_RS06610	COG0287	Prephenate dehydrogenase
SRT_RS06615	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SRT_RS06620	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SRT_RS06625	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SRT_RS06630	COG0710	3-dehydroquinate dehydratase activity
SRT_RS06635	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SRT_RS06640	COG1368	sulfuric ester hydrolase activity
SRT_RS06660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SRT_RS06665	COG0366	Alpha amylase catalytic
SRT_RS06665	COG5263	repeat protein
SRT_RS06680	COG4443	Transcriptional Coactivator p15 (PC4)
SRT_RS06695	COG0450	alkyl hydroperoxide reductase
SRT_RS06700	COG0826	peptidase U32
SRT_RS06730	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SRT_RS06735	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SRT_RS06745	COG3091	SprT-like family
SRT_RS06750	COG2183	response to ionizing radiation
SRT_RS06765	COG0701	Predicted permease
SRT_RS06770	COG3689	TIGRFAM TIGR03943 family protein
SRT_RS06775	COG0477	Major facilitator Superfamily
SRT_RS06780	COG0552	protein localization to endoplasmic reticulum
SRT_RS06785	COG0561	phosphatase activity
SRT_RS06790	COG0561	phosphatase activity
SRT_RS06810	COG1395	domain, Protein
SRT_RS06815	COG0604	alcohol dehydrogenase
SRT_RS06855	COG1078	dGTPase activity
SRT_RS06880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SRT_RS06890	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SRT_RS06925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SRT_RS06940	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SRT_RS06945	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SRT_RS07030	COG0656	L-ascorbic acid biosynthetic process
SRT_RS07035	COG0789	Transcriptional regulator
SRT_RS07040	COG1012	belongs to the aldehyde dehydrogenase family
SRT_RS07050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SRT_RS07060	COG0538	isocitrate dehydrogenase activity
SRT_RS07065	COG0372	Belongs to the citrate synthase family
SRT_RS07070	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SRT_RS07075	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SRT_RS07080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SRT_RS07090	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SRT_RS07095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SRT_RS07100	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SRT_RS07105	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SRT_RS07110	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SRT_RS07115	COG1266	CAAX protease self-immunity
SRT_RS07170	COG1131	(ABC) transporter
SRT_RS07190	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SRT_RS07200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SRT_RS07205	COG4122	O-methyltransferase activity
SRT_RS07210	COG0131	Imidazoleglycerol-phosphate dehydratase
SRT_RS07210	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SRT_RS07235	COG3321	synthase
SRT_RS07235	COG1028	Short-chain dehydrogenase reductase Sdr
SRT_RS07235	COG0604	alcohol dehydrogenase
SRT_RS07250	COG0363	glucosamine-6-phosphate deaminase activity
SRT_RS07260	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SRT_RS07290	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SRT_RS07305	COG2333	competence protein COMEC
SRT_RS07305	COG0658	competence protein
SRT_RS07310	COG1596	polysaccharide export
SRT_RS07310	COG1555	photosystem II stabilization
SRT_RS07315	COG0204	Acyl-transferase
SRT_RS07320	COG0726	polysaccharide deacetylase
SRT_RS07330	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SRT_RS07365	COG0513	Belongs to the DEAD box helicase family
SRT_RS07380	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SRT_RS07390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SRT_RS07395	COG0385	Bile acid
SRT_RS07405	COG1181	Belongs to the D-alanine--D-alanine ligase family
SRT_RS07410	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SRT_RS07415	COG0768	penicillin binding
SRT_RS07420	COG0588	phosphoglycerate mutase activity
SRT_RS07440	COG0735	belongs to the Fur family
SRT_RS07460	COG0776	regulation of translation
SRT_RS07470	COG2755	lipolytic protein G-D-S-L family
SRT_RS07475	COG1307	EDD domain protein, DegV family
SRT_RS07480	COG0497	DNA recombination
SRT_RS07485	COG1438	arginine binding
SRT_RS07490	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SRT_RS07500	COG1722	exodeoxyribonuclease VII activity
SRT_RS07505	COG1570	exodeoxyribonuclease VII activity
SRT_RS07510	COG3275	phosphorelay sensor kinase activity
SRT_RS07515	COG3279	Response regulator of the LytR AlgR family
SRT_RS07520	COG1380	Effector of murein hydrolase LrgA
SRT_RS07525	COG1346	cytolysis
SRT_RS07535	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SRT_RS07555	COG1126	abc transporter atp-binding protein
SRT_RS07560	COG0765	amino acid transport
SRT_RS07565	COG4703	Protein of unknown function (DUF1797)
SRT_RS07575	COG0542	response to heat
SRT_RS07590	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SRT_RS07595	COG3599	regulation of cell shape
SRT_RS07615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SRT_RS07635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SRT_RS07650	COG1217	gtp-binding protein TYPA
SRT_RS07660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SRT_RS07665	COG1940	carbohydrate kinase activity
SRT_RS07685	COG0159	tryptophan synthase activity
SRT_RS07690	COG0133	tryptophan synthase activity
SRT_RS07695	COG0135	phosphoribosylanthranilate isomerase activity
SRT_RS07700	COG0134	indole-3-glycerol-phosphate synthase activity
SRT_RS07710	COG0512	Glutamine amidotransferase of anthranilate synthase
SRT_RS07715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SRT_RS07735	COG3804	dihydrodipicolinate reductase
SRT_RS07745	COG1132	(ABC) transporter
SRT_RS07750	COG1132	(ABC) transporter
SRT_RS07760	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SRT_RS07765	COG4470	Protein conserved in bacteria
SRT_RS07770	COG0737	Belongs to the 5'-nucleotidase family
SRT_RS07780	COG0742	ribosomal rna small subunit methyltransferase
SRT_RS07785	COG4716	Myosin-crossreactive antigen
SRT_RS07825	COG0561	phosphatase activity
SRT_RS07830	COG1349	DNA-binding transcription factor activity
SRT_RS07860	COG1040	competence protein
SRT_RS07865	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SRT_RS07870	COG1739	Uncharacterized protein family UPF0029
SRT_RS07890	COG1882	Formate acetyltransferase
SRT_RS07900	COG1349	DNA-binding transcription factor activity
SRT_RS07910	COG1098	S1 RNA binding domain
SRT_RS07920	COG2197	response regulator
SRT_RS07925	COG4585	Histidine kinase
SRT_RS07945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SRT_RS07945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SRT_RS07950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SRT_RS07960	COG1758	RNA polymerase activity
SRT_RS07965	COG0194	GDP metabolic process
SRT_RS07970	COG1418	mRNA catabolic process
SRT_RS07970	COG4372	Transposase
SRT_RS07975	COG1854	S-ribosylhomocysteine lyase activity
SRT_RS07995	COG3599	regulation of cell shape
SRT_RS08000	COG4474	Belongs to the UPF0398 family
SRT_RS08005	COG3331	DNA recombination
SRT_RS08010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SRT_RS08015	COG3579	cysteine-type endopeptidase activity
SRT_RS08020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SRT_RS08025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SRT_RS08030	COG0492	ferredoxin-NADP+ reductase activity
SRT_RS08040	COG1126	abc transporter atp-binding protein
SRT_RS08050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SRT_RS08055	COG0513	Belongs to the DEAD box helicase family
SRT_RS08060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SRT_RS08070	COG4839	cell division protein FtsL
SRT_RS08075	COG0275	rRNA processing
SRT_RS08090	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SRT_RS08105	COG0751	glycine-tRNA ligase activity
SRT_RS08110	COG0752	glycyl-tRNA synthetase alpha subunit
SRT_RS08165	COG0561	phosphatase activity
SRT_RS08175	COG2217	Heavy metal translocating P-type atpase
SRT_RS08190	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SRT_RS08195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SRT_RS08205	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SRT_RS08210	COG0195	Participates in both transcription termination and antitermination
SRT_RS08215	COG0779	Required for maturation of 30S ribosomal subunits
SRT_RS08225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SRT_RS08240	COG1131	(ABC) transporter
SRT_RS08245	COG0537	adenosine 5'-monophosphoramidase activity
SRT_RS08255	COG1316	TRANSCRIPTIONal
SRT_RS08260	COG0802	atpase or kinase
SRT_RS08265	COG2252	PERMEase
SRT_RS08275	COG0561	phosphatase activity
SRT_RS08290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SRT_RS08305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SRT_RS08320	COG2936	dipeptidyl-peptidase activity
SRT_RS08325	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SRT_RS08335	COG2081	HI0933 family
SRT_RS08355	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SRT_RS08360	COG0456	acetyltransferase
SRT_RS08365	COG1214	PFAM Peptidase M22, glycoprotease
SRT_RS08375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SRT_RS08400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SRT_RS08415	COG2226	methyltransferase
SRT_RS08440	COG5503	Protein of unknown function (DUF1447)
SRT_RS08450	COG3942	CHAP domain
SRT_RS08455	COG0493	'glutamate synthase
SRT_RS08460	COG0070	glutamate synthase
SRT_RS08460	COG0067	glutamate synthase
SRT_RS08460	COG0069	glutamate synthase activity
SRT_RS08465	COG0174	glutamine synthetase
SRT_RS08470	COG0789	Transcriptional regulator
SRT_RS08480	COG0126	phosphoglycerate kinase activity
SRT_RS08490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SRT_RS08495	COG0049	tRNA binding
SRT_RS08500	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SRT_RS08510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SRT_RS08515	COG3481	metal-dependent phosphohydrolase, HD sub domain
SRT_RS08535	COG1162	GTPase activity
SRT_RS08585	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SRT_RS08605	COG0084	hydrolase, TatD family'
SRT_RS08610	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SRT_RS08625	COG0706	membrane insertase activity
SRT_RS08630	COG0594	ribonuclease P activity
SRT_RS08635	COG0165	Argininosuccinate lyase
SRT_RS08640	COG0137	argininosuccinate synthase activity
SRT_RS08655	COG1827	regulation of RNA biosynthetic process
SRT_RS08660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SRT_RS08685	COG0756	dUTP diphosphatase activity
SRT_RS08690	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SRT_RS08695	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SRT_RS08700	COG0457	Tetratricopeptide repeat
SRT_RS08700	COG0705	Rhomboid family
SRT_RS08705	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SRT_RS08715	COG1473	amidohydrolase
SRT_RS08720	COG2171	N-acyltransferase activity
SRT_RS08740	COG3731	PTS system glucitol sorbitol-specific IIA component
SRT_RS08745	COG3732	PTS system glucitol sorbitol-specific
SRT_RS08750	COG3730	PTS system glucitol sorbitol-specific
SRT_RS08760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SRT_RS08760	COG3711	transcriptional antiterminator
SRT_RS08770	COG0166	Belongs to the GPI family
SRT_RS08805	COG1234	tRNA 3'-trailer cleavage
SRT_RS08820	COG0343	queuine tRNA-ribosyltransferase activity
SRT_RS08830	COG1832	CoA-binding protein
SRT_RS08835	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SRT_RS08835	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SRT_RS08865	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SRT_RS08930	COG0110	maltose O-acetyltransferase activity
SRT_RS08945	COG0512	Glutamine amidotransferase of anthranilate synthase
SRT_RS08950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SRT_RS08965	COG2274	protein secretion by the type I secretion system
SRT_RS09005	COG3623	hexulose-6-phosphate isomerase
SRT_RS09015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SRT_RS09030	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SRT_RS09035	COG2918	glutathione biosynthetic process
SRT_RS09035	COG1181	Belongs to the D-alanine--D-alanine ligase family
SRT_RS09045	COG4608	Belongs to the ABC transporter superfamily
SRT_RS09050	COG0444	Belongs to the ABC transporter superfamily
SRT_RS09055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SRT_RS09060	COG0601	transmembrane transport
SRT_RS09065	COG4166	transmembrane transport
SRT_RS09080	COG0719	Fe-S assembly protein
SRT_RS09090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SRT_RS09095	COG0719	Fe-S assembly protein
SRT_RS09105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SRT_RS09110	COG4862	establishment of competence for transformation
SRT_RS09115	COG1968	undecaprenyl-diphosphatase activity
SRT_RS09125	COG0765	amino acid transport
SRT_RS09130	COG1126	abc transporter atp-binding protein
SRT_RS09140	COG1131	(ABC) transporter
SRT_RS09150	COG1309	transcriptional regulator
SRT_RS09160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SRT_RS09165	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SRT_RS09170	COG0440	acetolactate synthase activity
SRT_RS09175	COG0028	Belongs to the TPP enzyme family
SRT_RS09285	COG0203	ribosomal protein L17
SRT_RS09295	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SRT_RS09300	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SRT_RS09310	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SRT_RS09315	COG0563	adenylate kinase activity
SRT_RS09325	COG0200	Binds to the 23S rRNA
SRT_RS09330	COG1841	ribosomal large subunit assembly
SRT_RS09335	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SRT_RS09345	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SRT_RS09355	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SRT_RS09360	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SRT_RS09370	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SRT_RS09375	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SRT_RS09380	COG0255	Belongs to the universal ribosomal protein uL29 family
SRT_RS09385	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SRT_RS09390	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SRT_RS09395	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SRT_RS09405	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SRT_RS09410	COG0089	rRNA binding
SRT_RS09425	COG0051	transcription antitermination factor activity, RNA binding
SRT_RS09435	COG1621	beta-fructofuranosidase activity
SRT_RS09440	COG0542	response to heat
SRT_RS09445	COG4463	regulation of RNA biosynthetic process
SRT_RS09455	COG0477	Major facilitator Superfamily
SRT_RS09480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SRT_RS09500	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SRT_RS09505	COG0052	Belongs to the universal ribosomal protein uS2 family
SRT_RS09520	COG1619	proteins homologs of microcin C7 resistance protein MccF
SRT_RS09525	COG3590	peptidase
SRT_RS09560	COG1131	(ABC) transporter
SRT_RS09595	COG1136	(ABC) transporter
SRT_RS09595	COG0577	efflux transmembrane transporter activity
SRT_RS09610	COG1132	(ABC) transporter
SRT_RS09620	COG0366	Alpha amylase catalytic
SRT_RS09625	COG1263	PTS System
SRT_RS09625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SRT_RS09635	COG5297	Belongs to the glycosyl hydrolase family 6
SRT_RS09640	COG1490	D-aminoacyl-tRNA deacylase activity
SRT_RS09665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SRT_RS09670	COG2264	protein methyltransferase activity
SRT_RS09690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SRT_RS09705	COG2217	Heavy metal translocating P-type atpase
SRT_RS09725	COG1136	(ABC) transporter
SRT_RS09725	COG0577	efflux transmembrane transporter activity
SRT_RS09735	COG1250	3-hydroxyacyl-CoA dehydrogenase
SRT_RS09775	COG2855	membrane
SRT_RS09780	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SRT_RS09785	COG4485	Bacterial membrane protein, YfhO
SRT_RS09790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SRT_RS09800	COG0463	Glycosyl transferase, family 2
SRT_RS09805	COG0428	transporter
SRT_RS09810	COG3022	response to hydroperoxide
SRT_RS09845	COG3906	Belongs to the UPF0473 family
SRT_RS09850	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SRT_RS09855	COG4472	Bacterial protein of unknown function (DUF965)
SRT_RS09880	COG1393	Belongs to the ArsC family
SRT_RS09885	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SRT_RS09890	COG1546	Belongs to the CinA family
SRT_RS09890	COG1058	Belongs to the CinA family
SRT_RS09895	COG0519	Catalyzes the synthesis of GMP from XMP
SRT_RS09900	COG0632	four-way junction helicase activity
SRT_RS09905	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SRT_RS09910	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SRT_RS09915	COG4550	Control of competence regulator ComK, YlbF/YmcA
SRT_RS09925	COG0018	arginyl-trna synthetase
SRT_RS09935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SRT_RS09940	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SRT_RS09945	COG0124	histidyl-tRNA synthetase
SRT_RS09975	COG0640	Transcriptional regulator
SRT_RS10010	COG0463	Glycosyl transferase, family 2
SRT_RS10035	COG1028	Short-chain dehydrogenase reductase Sdr
SRT_RS10050	COG1732	Glycine betaine
SRT_RS10060	COG2094	Belongs to the DNA glycosylase MPG family
SRT_RS10080	COG1012	belongs to the aldehyde dehydrogenase family
SRT_RS10085	COG0129	dihydroxy-acid dehydratase activity
SRT_RS10090	COG2151	metal-sulfur cluster biosynthetic enzyme
SRT_RS10110	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SRT_RS10120	COG0305	Participates in initiation and elongation during chromosome replication
SRT_RS10125	COG0359	binds to the 23S rRNA
SRT_RS10135	COG0445	tRNA wobble uridine modification
SRT_RS10145	COG0482	sulfurtransferase activity
SRT_RS10160	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SRT_RS10165	COG1122	ATPase activity
SRT_RS10170	COG1122	ATPase activity
SRT_RS10175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SRT_RS10200	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SRT_RS10205	COG0516	GMP reductase activity
SRT_RS10205	COG0517	IMP dehydrogenase activity
SRT_RS10215	COG0488	(ABC) transporter
SRT_RS10250	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SRT_RS10255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SRT_RS10260	COG1475	DNA binding
