locus-tag	class	description
CGZ53_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CGZ53_RS00010	COG0592	DNA-directed DNA polymerase activity
CGZ53_RS00015	COG4481	Protein conserved in bacteria
CGZ53_RS00025	COG0012	GTP binding
CGZ53_RS00030	COG0193	aminoacyl-tRNA hydrolase activity
CGZ53_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CGZ53_RS00040	COG2244	polysaccharide biosynthetic process
CGZ53_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CGZ53_RS00065	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CGZ53_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CGZ53_RS00075	COG0531	amino acid
CGZ53_RS00195	COG3942	CHAP domain
CGZ53_RS00205	COG0436	Aminotransferase
CGZ53_RS00215	COG0416	fatty acid biosynthetic process
CGZ53_RS00220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CGZ53_RS00225	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CGZ53_RS00230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CGZ53_RS00240	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CGZ53_RS00245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CGZ53_RS00250	COG0138	bifunctional purine biosynthesis protein purh
CGZ53_RS00285	COG2188	Transcriptional regulator
CGZ53_RS00290	COG2222	sugar isomerase
CGZ53_RS00310	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGZ53_RS00315	COG3715	PTS system
CGZ53_RS00320	COG3716	PTS system mannose fructose sorbose family IID component
CGZ53_RS00330	COG0860	N-Acetylmuramoyl-L-alanine amidase
CGZ53_RS00330	COG1388	LysM domain
CGZ53_RS00340	COG0151	Belongs to the GarS family
CGZ53_RS00345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CGZ53_RS00355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CGZ53_RS00365	COG2255	four-way junction helicase activity
CGZ53_RS00370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGZ53_RS00380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CGZ53_RS00380	COG2755	lipolytic protein G-D-S-L family
CGZ53_RS00385	COG1454	alcohol dehydrogenase
CGZ53_RS00385	COG1012	belongs to the aldehyde dehydrogenase family
CGZ53_RS00400	COG0534	Mate efflux family protein
CGZ53_RS00405	COG0051	transcription antitermination factor activity, RNA binding
CGZ53_RS00410	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CGZ53_RS00415	COG0088	Forms part of the polypeptide exit tunnel
CGZ53_RS00420	COG0089	rRNA binding
CGZ53_RS00425	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CGZ53_RS00435	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CGZ53_RS00440	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CGZ53_RS00445	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CGZ53_RS00455	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CGZ53_RS00460	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CGZ53_RS00465	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CGZ53_RS00470	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CGZ53_RS00480	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CGZ53_RS00485	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CGZ53_RS00500	COG1841	ribosomal large subunit assembly
CGZ53_RS00505	COG0200	Binds to the 23S rRNA
CGZ53_RS00510	COG0201	protein transport
CGZ53_RS00515	COG0563	adenylate kinase activity
CGZ53_RS00530	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CGZ53_RS00545	COG0203	ribosomal protein L17
CGZ53_RS00635	COG0582	viral genome integration into host DNA
CGZ53_RS00705	COG1252	NADH dehydrogenase
CGZ53_RS00710	COG1271	oxidase subunit
CGZ53_RS00715	COG1294	oxidase, subunit
CGZ53_RS00720	COG4988	ABC transporter
CGZ53_RS00725	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CGZ53_RS00730	COG0142	geranyltranstransferase activity
CGZ53_RS00735	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CGZ53_RS00745	COG1121	(ABC) transporter
CGZ53_RS00750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CGZ53_RS00755	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CGZ53_RS00760	COG4499	WXG100 protein secretion system (Wss), protein YukC
CGZ53_RS00760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGZ53_RS00765	COG0085	RNA polymerase activity
CGZ53_RS00770	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CGZ53_RS00780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CGZ53_RS00785	COG1459	type II secretion system
CGZ53_RS00790	COG4537	Required for transformation and DNA binding
CGZ53_RS00820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CGZ53_RS00835	COG1266	CAAX protease self-immunity
CGZ53_RS00840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CGZ53_RS00845	COG1363	Peptidase, m42
CGZ53_RS00855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CGZ53_RS00860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CGZ53_RS00865	COG5492	domain, Protein
CGZ53_RS00865	COG1621	beta-fructofuranosidase activity
CGZ53_RS00865	COG3583	domain protein
CGZ53_RS00885	COG4120	Belongs to the binding-protein-dependent transport system permease family
CGZ53_RS00890	COG1122	ATPase activity
CGZ53_RS00895	COG1428	Deoxynucleoside kinase
CGZ53_RS00900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CGZ53_RS00905	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CGZ53_RS00935	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CGZ53_RS00945	COG1744	ABC transporter substrate-binding protein PnrA-like
CGZ53_RS00950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CGZ53_RS00960	COG2390	Transcriptional regulator
CGZ53_RS00970	COG1882	Formate acetyltransferase
CGZ53_RS00985	COG1175	transmembrane transport
CGZ53_RS00990	COG0395	ABC-type sugar transport system, permease component
CGZ53_RS01010	COG3842	ATPase activity
CGZ53_RS01025	COG1785	Belongs to the alkaline phosphatase family
CGZ53_RS01030	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CGZ53_RS01055	COG0673	inositol 2-dehydrogenase activity
CGZ53_RS01060	COG1902	pentaerythritol trinitrate reductase activity
CGZ53_RS01065	COG2226	methyltransferase
CGZ53_RS01095	COG0561	phosphatase activity
CGZ53_RS01105	COG4585	Histidine kinase
CGZ53_RS01110	COG2197	response regulator
CGZ53_RS01135	COG3716	PTS system mannose fructose sorbose family IID component
CGZ53_RS01150	COG5002	protein histidine kinase activity
CGZ53_RS01150	COG3850	Histidine kinase
CGZ53_RS01155	COG0745	RESPONSE REGULATOR receiver
CGZ53_RS01165	COG5002	protein histidine kinase activity
CGZ53_RS01170	COG0745	RESPONSE REGULATOR receiver
CGZ53_RS01180	COG0577	efflux transmembrane transporter activity
CGZ53_RS01185	COG2199	diguanylate cyclase activity
CGZ53_RS01230	COG1611	Belongs to the LOG family
CGZ53_RS01270	COG2946	Replication initiation factor
CGZ53_RS01295	COG1395	domain, Protein
CGZ53_RS01305	COG1131	(ABC) transporter
CGZ53_RS01325	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CGZ53_RS01340	COG2264	protein methyltransferase activity
CGZ53_RS01345	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CGZ53_RS01350	COG1609	Transcriptional regulator
CGZ53_RS01355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGZ53_RS01355	COG1263	PTS System
CGZ53_RS01355	COG2190	(PTS) system
CGZ53_RS01370	COG1363	Peptidase, m42
CGZ53_RS01380	COG0737	Belongs to the 5'-nucleotidase family
CGZ53_RS01390	COG1490	D-aminoacyl-tRNA deacylase activity
CGZ53_RS01400	COG3842	ATPase activity
CGZ53_RS01425	COG3118	belongs to the thioredoxin family
CGZ53_RS01430	COG1862	Preprotein translocase
CGZ53_RS01440	COG4589	Belongs to the CDS family
CGZ53_RS01450	COG0442	prolyl-tRNA aminoacylation
CGZ53_RS01475	COG0242	peptide deformylase activity
CGZ53_RS01480	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CGZ53_RS01505	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CGZ53_RS01510	COG1185	polyribonucleotide nucleotidyltransferase activity
CGZ53_RS01520	COG1045	serine acetyltransferase
CGZ53_RS01530	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CGZ53_RS01540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGZ53_RS01555	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CGZ53_RS01560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CGZ53_RS01610	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CGZ53_RS01690	COG3842	ATPase activity
CGZ53_RS01720	COG2267	carboxylic ester hydrolase activity
CGZ53_RS01725	COG1609	Transcriptional regulator
CGZ53_RS01730	COG4209	transmembrane transport
CGZ53_RS01735	COG0395	ABC-type sugar transport system, permease component
CGZ53_RS01740	COG1653	transport
CGZ53_RS01745	COG1621	beta-fructofuranosidase activity
CGZ53_RS01750	COG1940	carbohydrate kinase activity
CGZ53_RS01755	COG2723	6-phospho-beta-galactosidase activity
CGZ53_RS01760	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CGZ53_RS01770	COG1122	ATPase activity
CGZ53_RS01775	COG4720	Psort location CytoplasmicMembrane, score
CGZ53_RS01785	COG0561	phosphatase activity
CGZ53_RS01820	COG0527	aspartate kinase activity
CGZ53_RS01825	COG0101	tRNA pseudouridine synthase activity
CGZ53_RS01830	COG0351	phosphomethylpyrimidine kinase
CGZ53_RS01835	COG4720	Psort location CytoplasmicMembrane, score
CGZ53_RS01845	COG0668	transmembrane transport
CGZ53_RS01850	COG0544	peptidyl-prolyl cis-trans isomerase activity
CGZ53_RS01855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGZ53_RS01860	COG3343	RNA polymerase activity
CGZ53_RS01865	COG0504	CTP synthase activity
CGZ53_RS01890	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CGZ53_RS01915	COG1126	abc transporter atp-binding protein
CGZ53_RS01920	COG0765	amino acid transport
CGZ53_RS01935	COG4862	establishment of competence for transformation
CGZ53_RS01940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CGZ53_RS01955	COG0719	Fe-S assembly protein
CGZ53_RS01960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CGZ53_RS01980	COG1686	Belongs to the peptidase S11 family
CGZ53_RS01985	COG1686	Belongs to the peptidase S11 family
CGZ53_RS01990	COG1686	Belongs to the peptidase S11 family
CGZ53_RS02035	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CGZ53_RS02040	COG1534	Rna-binding protein
CGZ53_RS02045	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CGZ53_RS02050	COG1713	HD superfamily hydrolase involved in NAD metabolism
CGZ53_RS02055	COG0799	negative regulation of ribosome biogenesis
CGZ53_RS02060	COG2226	methyltransferase
CGZ53_RS02065	COG1323	Belongs to the UPF0348 family
CGZ53_RS02085	COG0217	transcriptional regulatory protein
CGZ53_RS02090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGZ53_RS02095	COG1464	Belongs to the NlpA lipoprotein family
CGZ53_RS02100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CGZ53_RS02115	COG1114	Component of the transport system for branched-chain amino acids
CGZ53_RS02120	COG0569	domain protein
CGZ53_RS02125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CGZ53_RS02130	COG0357	Ribosomal RNA small subunit methyltransferase G
CGZ53_RS02135	COG1704	LemA family
CGZ53_RS02140	COG0501	Belongs to the peptidase M48B family
CGZ53_RS02150	COG0745	RESPONSE REGULATOR receiver
CGZ53_RS02160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CGZ53_RS02170	COG1484	DNA-dependent DNA replication
CGZ53_RS02175	COG1160	GTP binding
CGZ53_RS02180	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CGZ53_RS02210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CGZ53_RS02215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CGZ53_RS02225	COG1254	Belongs to the acylphosphatase family
CGZ53_RS02230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGZ53_RS02250	COG3763	UPF0154 protein
CGZ53_RS02260	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CGZ53_RS02270	COG0622	Phosphoesterase
CGZ53_RS02275	COG1125	glycine betaine transport
CGZ53_RS02275	COG0517	IMP dehydrogenase activity
CGZ53_RS02280	COG0582	viral genome integration into host DNA
CGZ53_RS02285	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CGZ53_RS02295	COG1187	pseudouridine synthase activity
CGZ53_RS02300	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CGZ53_RS02310	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CGZ53_RS02315	COG0671	phosphoesterase, PA-phosphatase related
CGZ53_RS02320	COG1242	4 iron, 4 sulfur cluster binding
CGZ53_RS02325	COG1131	(ABC) transporter
CGZ53_RS02340	COG1253	flavin adenine dinucleotide binding
CGZ53_RS02345	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CGZ53_RS02350	COG1227	inorganic diphosphatase activity
CGZ53_RS02365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGZ53_RS02370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGZ53_RS02375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CGZ53_RS02380	COG1120	ATPase activity
CGZ53_RS02390	COG2244	polysaccharide biosynthetic process
CGZ53_RS02395	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CGZ53_RS02400	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CGZ53_RS02405	COG0740	serine-type endopeptidase activity
CGZ53_RS02415	COG4471	UPF0298 protein
CGZ53_RS02445	COG0517	IMP dehydrogenase activity
CGZ53_RS02450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CGZ53_RS02455	COG0470	DNA polymerase III
CGZ53_RS02460	COG1774	PSP1 C-terminal conserved region
CGZ53_RS02485	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CGZ53_RS02495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGZ53_RS02505	COG1393	Belongs to the ArsC family
CGZ53_RS02530	COG0708	Exodeoxyribonuclease III
CGZ53_RS02535	COG0640	Transcriptional regulator
CGZ53_RS02570	COG1114	Component of the transport system for branched-chain amino acids
CGZ53_RS02585	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ53_RS02590	COG0673	inositol 2-dehydrogenase activity
CGZ53_RS02595	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CGZ53_RS02610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CGZ53_RS02635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CGZ53_RS02655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CGZ53_RS02660	COG0081	regulation of translation
CGZ53_RS02670	COG0233	cytoplasmic translational termination
CGZ53_RS02680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CGZ53_RS02685	COG4479	Belongs to the UPF0346 family
CGZ53_RS02690	COG1702	phosphate starvation-inducible protein PhoH
CGZ53_RS02695	COG1573	uracil-dna glycosylase
CGZ53_RS02700	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CGZ53_RS02705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CGZ53_RS02710	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CGZ53_RS02730	COG1131	(ABC) transporter
CGZ53_RS02795	COG2364	Membrane
CGZ53_RS02800	COG0433	COG0433 Predicted ATPase
CGZ53_RS02805	COG2814	Major facilitator Superfamily
CGZ53_RS02820	COG0557	exoribonuclease II activity
CGZ53_RS02825	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CGZ53_RS02830	COG0463	Glycosyl transferase, family 2
CGZ53_RS02835	COG0346	lactoylglutathione lyase activity
CGZ53_RS02840	COG0778	Nitroreductase
CGZ53_RS02855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGZ53_RS02855	COG3711	transcriptional antiterminator
CGZ53_RS02860	COG1447	Phosphotransferase system cellobiose-specific component IIA
CGZ53_RS02870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CGZ53_RS02880	COG0006	proline dipeptidase activity
CGZ53_RS02885	COG1609	Transcriptional regulator
CGZ53_RS02900	COG0438	transferase activity, transferring glycosyl groups
CGZ53_RS02905	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CGZ53_RS02910	COG2376	Dihydroxyacetone kinase
CGZ53_RS02920	COG2376	Dihydroxyacetone kinase
CGZ53_RS02925	COG1461	Dihydroxyacetone kinase
CGZ53_RS02930	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CGZ53_RS02935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CGZ53_RS02945	COG0765	amino acid transport
CGZ53_RS02950	COG0765	amino acid transport
CGZ53_RS02955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGZ53_RS02960	COG1126	abc transporter atp-binding protein
CGZ53_RS02965	COG0745	RESPONSE REGULATOR receiver
CGZ53_RS02970	COG5002	protein histidine kinase activity
CGZ53_RS02975	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CGZ53_RS02980	COG0571	ribonuclease III activity
CGZ53_RS02985	COG1196	nuclear chromosome segregation
CGZ53_RS02990	COG0561	phosphatase activity
CGZ53_RS02995	COG0561	phosphatase activity
CGZ53_RS03000	COG0552	protein localization to endoplasmic reticulum
CGZ53_RS03020	COG3689	TIGRFAM TIGR03943 family protein
CGZ53_RS03025	COG0701	Predicted permease
CGZ53_RS03030	COG0346	lactoylglutathione lyase activity
CGZ53_RS03035	COG0745	RESPONSE REGULATOR receiver
CGZ53_RS03040	COG5002	protein histidine kinase activity
CGZ53_RS03045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CGZ53_RS03050	COG0573	inorganic phosphate transmembrane transporter activity
CGZ53_RS03055	COG0581	inorganic phosphate transmembrane transporter activity
CGZ53_RS03060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CGZ53_RS03065	COG0704	Plays a role in the regulation of phosphate uptake
CGZ53_RS03070	COG2183	response to ionizing radiation
CGZ53_RS03075	COG3091	SprT-like family
CGZ53_RS03085	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CGZ53_RS03090	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CGZ53_RS03115	COG0826	peptidase U32
CGZ53_RS03125	COG4443	Transcriptional Coactivator p15 (PC4)
CGZ53_RS03130	COG4166	transmembrane transport
CGZ53_RS03140	COG0004	ammonium transporteR
CGZ53_RS03160	COG0588	phosphoglycerate mutase activity
CGZ53_RS03165	COG3304	Inner membrane component domain
CGZ53_RS03170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CGZ53_RS03175	COG3859	Proton-coupled thiamine transporter YuaJ
CGZ53_RS03195	COG1164	Oligoendopeptidase f
CGZ53_RS03205	COG0772	Belongs to the SEDS family
CGZ53_RS03210	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CGZ53_RS03235	COG1078	dGTPase activity
CGZ53_RS03260	COG0584	glycerophosphoryl diester phosphodiesterase
CGZ53_RS03270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGZ53_RS03275	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CGZ53_RS03280	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CGZ53_RS03290	COG2884	Cell division ATP-binding protein ftsE
CGZ53_RS03295	COG2177	Part of the ABC transporter FtsEX involved in
CGZ53_RS03315	COG0436	Aminotransferase
CGZ53_RS03320	COG0017	Asparaginyl-tRNA synthetase
CGZ53_RS03325	COG1660	Displays ATPase and GTPase activities
CGZ53_RS03350	COG0254	rRNA binding
CGZ53_RS03355	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CGZ53_RS03360	COG2153	protein acetylation
CGZ53_RS03370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CGZ53_RS03375	COG0625	glutathione transferase activity
CGZ53_RS03380	COG0716	FMN binding
CGZ53_RS03385	COG1605	Chorismate mutase
CGZ53_RS03385	COG0287	Prephenate dehydrogenase
CGZ53_RS03390	COG0038	chloride channel
CGZ53_RS03395	COG0335	large ribosomal subunit rRNA binding
CGZ53_RS03410	COG0772	Belongs to the SEDS family
CGZ53_RS03425	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CGZ53_RS03430	COG0560	Phosphoserine phosphatase
CGZ53_RS03450	COG0148	phosphopyruvate hydratase activity
CGZ53_RS03455	COG1278	Cold shock
CGZ53_RS03460	COG4708	membrane
CGZ53_RS03465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CGZ53_RS03470	COG1597	lipid kinase activity
CGZ53_RS03475	COG1523	belongs to the glycosyl hydrolase 13 family
CGZ53_RS03480	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CGZ53_RS03485	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CGZ53_RS03490	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CGZ53_RS03495	COG0297	glycogen (starch) synthase activity
CGZ53_RS03500	COG0058	SHG alpha-glucan phosphorylase activity
CGZ53_RS03520	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CGZ53_RS03525	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CGZ53_RS03530	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CGZ53_RS03535	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CGZ53_RS03540	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CGZ53_RS03565	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CGZ53_RS03585	COG0577	efflux transmembrane transporter activity
CGZ53_RS03590	COG1136	(ABC) transporter
CGZ53_RS03595	COG2321	neutral zinc metallopeptidase
CGZ53_RS03600	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CGZ53_RS03605	COG1074	ATP-dependent DNA helicase activity
CGZ53_RS03625	COG1970	mechanosensitive ion channel activity
CGZ53_RS03630	COG0358	DNA primase activity
CGZ53_RS03635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGZ53_RS03640	COG2151	metal-sulfur cluster biosynthetic enzyme
CGZ53_RS03645	COG1091	dTDP-4-dehydrorhamnose reductase activity
CGZ53_RS03655	COG0463	Glycosyl transferase, family 2
CGZ53_RS03695	COG0463	Glycosyl transferase, family 2
CGZ53_RS03705	COG0860	N-Acetylmuramoyl-L-alanine amidase
CGZ53_RS03710	COG2195	Cleaves the N-terminal amino acid of tripeptides
CGZ53_RS03730	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CGZ53_RS03735	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CGZ53_RS03740	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CGZ53_RS03745	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CGZ53_RS03750	COG1368	sulfuric ester hydrolase activity
CGZ53_RS03755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CGZ53_RS03765	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CGZ53_RS03770	COG3679	Belongs to the UPF0342 family
CGZ53_RS03775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CGZ53_RS03785	COG1104	cysteine desulfurase activity
CGZ53_RS03790	COG0301	tRNA thio-modification
CGZ53_RS03805	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CGZ53_RS03815	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CGZ53_RS03830	COG0564	pseudouridine synthase activity
CGZ53_RS03835	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CGZ53_RS03845	COG0540	Belongs to the ATCase OTCase family
CGZ53_RS03855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CGZ53_RS03865	COG1136	(ABC) transporter
CGZ53_RS03870	COG0577	efflux transmembrane transporter activity
CGZ53_RS03880	COG0584	glycerophosphoryl diester phosphodiesterase
CGZ53_RS03885	COG0228	four-way junction DNA binding
CGZ53_RS03890	COG1837	Belongs to the UPF0109 family
CGZ53_RS03895	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CGZ53_RS03900	COG0336	Belongs to the RNA methyltransferase TrmD family
CGZ53_RS03920	COG1349	DNA-binding transcription factor activity
CGZ53_RS03925	COG1105	Belongs to the carbohydrate kinase PfkB family
CGZ53_RS03930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGZ53_RS03930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGZ53_RS03930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGZ53_RS03935	COG1705	Flagellar rod assembly protein muramidase FlgJ
CGZ53_RS03935	COG3942	CHAP domain
CGZ53_RS03940	COG1705	Flagellar rod assembly protein muramidase FlgJ
CGZ53_RS03940	COG1388	LysM domain
CGZ53_RS03960	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CGZ53_RS03965	COG0617	tRNA 3'-terminal CCA addition
CGZ53_RS03970	COG0488	(ABC) transporter
CGZ53_RS03985	COG1132	(ABC) transporter
CGZ53_RS03990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CGZ53_RS03995	COG0242	peptide deformylase activity
CGZ53_RS04000	COG0737	Belongs to the 5'-nucleotidase family
CGZ53_RS04030	COG3425	synthase
CGZ53_RS04035	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CGZ53_RS04040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGZ53_RS04050	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CGZ53_RS04055	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CGZ53_RS04070	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CGZ53_RS04075	COG0222	ribosome binding
CGZ53_RS04095	COG1349	DNA-binding transcription factor activity
CGZ53_RS04105	COG0698	ribose 5-phosphate isomerase
CGZ53_RS04110	COG1105	Belongs to the carbohydrate kinase PfkB family
CGZ53_RS04115	COG3684	Belongs to the aldolase LacD family
CGZ53_RS04120	COG3711	transcriptional antiterminator
CGZ53_RS04125	COG1447	Phosphotransferase system cellobiose-specific component IIA
CGZ53_RS04135	COG2723	6-phospho-beta-galactosidase activity
CGZ53_RS04150	COG1396	sequence-specific DNA binding
CGZ53_RS04165	COG1486	melibiose metabolic process
CGZ53_RS04170	COG1737	Transcriptional regulator
CGZ53_RS04180	COG0726	polysaccharide deacetylase
CGZ53_RS04185	COG0460	homoserine dehydrogenase
CGZ53_RS04190	COG0083	homoserine kinase activity
CGZ53_RS04195	COG0285	dihydrofolate synthase activity
CGZ53_RS04220	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CGZ53_RS04230	COG1176	ABC-type spermidine putrescine transport system, permease component I
CGZ53_RS04235	COG1177	transmembrane transport
CGZ53_RS04250	COG0038	chloride channel
CGZ53_RS04255	COG3711	transcriptional antiterminator
CGZ53_RS04260	COG1263	PTS System
CGZ53_RS04260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGZ53_RS04260	COG2190	(PTS) system
CGZ53_RS04265	COG2207	Transcriptional regulator
CGZ53_RS04270	COG2723	6-phospho-beta-galactosidase activity
CGZ53_RS04280	COG0561	phosphatase activity
CGZ53_RS04285	COG2723	6-phospho-beta-galactosidase activity
CGZ53_RS04295	COG0406	alpha-ribazole phosphatase activity
CGZ53_RS04305	COG2723	6-phospho-beta-galactosidase activity
CGZ53_RS04310	COG0628	permease
CGZ53_RS04315	COG2003	Belongs to the UPF0758 family
CGZ53_RS04320	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CGZ53_RS04325	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CGZ53_RS04340	COG1104	cysteine desulfurase activity
CGZ53_RS04355	COG2357	RelA SpoT domain protein
CGZ53_RS04365	COG0564	pseudouridine synthase activity
CGZ53_RS04370	COG0280	phosphate acetyltransferase
CGZ53_RS04375	COG4221	oxidoreductase activity
CGZ53_RS04385	COG0561	phosphatase activity
CGZ53_RS04390	COG0604	alcohol dehydrogenase
CGZ53_RS04390	COG3321	synthase
CGZ53_RS04390	COG4221	oxidoreductase activity
CGZ53_RS04390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CGZ53_RS04405	COG1174	glycine betaine transport
CGZ53_RS04410	COG2723	6-phospho-beta-galactosidase activity
CGZ53_RS04415	COG0516	GMP reductase activity
CGZ53_RS04420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CGZ53_RS04425	COG2233	PERMEase
CGZ53_RS04445	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CGZ53_RS04450	COG2890	protein-(glutamine-N5) methyltransferase activity
CGZ53_RS04455	COG0009	L-threonylcarbamoyladenylate synthase
CGZ53_RS04460	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CGZ53_RS04480	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGZ53_RS04485	COG0039	L-malate dehydrogenase activity
CGZ53_RS04495	COG3764	Sortase (surface protein transpeptidase)
CGZ53_RS04500	COG0346	lactoylglutathione lyase activity
CGZ53_RS04510	COG0803	Belongs to the bacterial solute-binding protein 9 family
CGZ53_RS04520	COG1811	Na channel or pump
CGZ53_RS04540	COG3104	oligopeptide transport
CGZ53_RS04550	COG0519	Catalyzes the synthesis of GMP from XMP
CGZ53_RS04550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CGZ53_RS04560	COG2188	Transcriptional regulator
CGZ53_RS04570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CGZ53_RS04585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CGZ53_RS04595	COG0673	inositol 2-dehydrogenase activity
CGZ53_RS04615	COG0656	L-ascorbic acid biosynthetic process
CGZ53_RS04620	COG1737	Transcriptional regulator
CGZ53_RS04625	COG2723	6-phospho-beta-galactosidase activity
CGZ53_RS04630	COG0662	Cupin 2, conserved barrel domain protein
CGZ53_RS04665	COG4974	Belongs to the 'phage' integrase family
CGZ53_RS04670	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CGZ53_RS04685	COG0745	RESPONSE REGULATOR receiver
CGZ53_RS04690	COG0577	efflux transmembrane transporter activity
CGZ53_RS04695	COG1136	(ABC) transporter
CGZ53_RS04710	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CGZ53_RS04725	COG0583	DNA-binding transcription factor activity
CGZ53_RS04730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CGZ53_RS04735	COG0758	DNA mediated transformation
CGZ53_RS04740	COG0110	maltose O-acetyltransferase activity
CGZ53_RS04745	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CGZ53_RS04760	COG1272	protein, Hemolysin III
CGZ53_RS04775	COG0488	(ABC) transporter
CGZ53_RS04780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CGZ53_RS04785	COG1328	CTP reductase activity
CGZ53_RS04785	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CGZ53_RS04790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGZ53_RS04795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CGZ53_RS04805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGZ53_RS04815	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CGZ53_RS04825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CGZ53_RS04830	COG4684	Psort location CytoplasmicMembrane, score
CGZ53_RS04835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGZ53_RS04840	COG1079	Belongs to the binding-protein-dependent transport system permease family
CGZ53_RS04845	COG4603	Belongs to the binding-protein-dependent transport system permease family
CGZ53_RS04850	COG3845	ABC transporter
CGZ53_RS04855	COG1744	ABC transporter substrate-binding protein PnrA-like
CGZ53_RS04860	COG0295	cytidine deaminase activity
CGZ53_RS04865	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CGZ53_RS04870	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CGZ53_RS04875	COG2813	Specifically methylates the guanine in position
CGZ53_RS04885	COG0268	Binds directly to 16S ribosomal RNA
CGZ53_RS04890	COG5002	protein histidine kinase activity
CGZ53_RS04895	COG0745	RESPONSE REGULATOR receiver
CGZ53_RS04905	COG0704	Plays a role in the regulation of phosphate uptake
CGZ53_RS04920	COG0581	inorganic phosphate transmembrane transporter activity
CGZ53_RS04925	COG0573	inorganic phosphate transmembrane transporter activity
CGZ53_RS04935	COG0483	inositol monophosphate 1-phosphatase activity
CGZ53_RS04940	COG4476	Belongs to the UPF0223 family
CGZ53_RS04950	COG0196	riboflavin kinase activity
CGZ53_RS04980	COG4591	ABC-type transport system involved in lipoprotein release permease component
CGZ53_RS04980	COG1136	(ABC) transporter
CGZ53_RS05025	COG2261	transglycosylase associated protein
CGZ53_RS05030	COG2261	transglycosylase associated protein
CGZ53_RS05035	COG0210	DNA helicase
CGZ53_RS05040	COG1115	amino acid carrier protein
CGZ53_RS05045	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CGZ53_RS05050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGZ53_RS05055	COG1126	abc transporter atp-binding protein
CGZ53_RS05060	COG0765	amino acid transport
CGZ53_RS05065	COG2824	Alkylphosphonate utilization operon protein PhnA
CGZ53_RS05070	COG0246	Mannitol dehydrogenase
CGZ53_RS05075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGZ53_RS05080	COG3711	transcriptional antiterminator
CGZ53_RS05085	COG2213	PTS system mannitol-specific
CGZ53_RS05100	COG0469	pyruvate kinase activity
CGZ53_RS05105	COG0205	6-phosphofructokinase activity
CGZ53_RS05115	COG1725	Transcriptional regulator
CGZ53_RS05120	COG1131	(ABC) transporter
CGZ53_RS05150	COG0539	negative regulation of cytoplasmic translation
CGZ53_RS05170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CGZ53_RS05185	COG0187	DNA topoisomerase II activity
CGZ53_RS05200	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CGZ53_RS05205	COG0765	amino acid transport
CGZ53_RS05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGZ53_RS05220	COG1881	PFAM PEBP family protein
CGZ53_RS05235	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CGZ53_RS05240	COG0284	orotidine-5'-phosphate decarboxylase activity
CGZ53_RS05270	COG0438	transferase activity, transferring glycosyl groups
CGZ53_RS05300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CGZ53_RS05325	COG1316	TRANSCRIPTIONal
CGZ53_RS05340	COG0813	purine-nucleoside phosphorylase activity
CGZ53_RS05355	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CGZ53_RS05360	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CGZ53_RS05390	COG0322	excinuclease ABC activity
CGZ53_RS05395	COG0561	phosphatase activity
CGZ53_RS05400	COG1012	belongs to the aldehyde dehydrogenase family
CGZ53_RS05405	COG1011	Hydrolase
CGZ53_RS05410	COG2259	Doxx family
CGZ53_RS05415	COG0656	L-ascorbic acid biosynthetic process
CGZ53_RS05420	COG2059	Chromate
CGZ53_RS05450	COG0446	pyridine nucleotide-disulphide oxidoreductase
CGZ53_RS05460	COG0667	Aldo Keto reductase
CGZ53_RS05465	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGZ53_RS05475	COG0789	Transcriptional regulator
CGZ53_RS05485	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ53_RS05490	COG0656	L-ascorbic acid biosynthetic process
CGZ53_RS05500	COG1418	mRNA catabolic process
CGZ53_RS05510	COG0481	GTPase activity
CGZ53_RS05520	COG0105	UTP biosynthetic process
CGZ53_RS05525	COG0210	DNA helicase
CGZ53_RS05540	COG0647	UMP catabolic process
CGZ53_RS05550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CGZ53_RS05560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGZ53_RS05570	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CGZ53_RS05575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CGZ53_RS05580	COG3442	glutamine amidotransferase
CGZ53_RS05590	COG2207	Transcriptional regulator
CGZ53_RS05590	COG3708	Transcriptional regulator
CGZ53_RS05595	COG0095	Lipoate-protein ligase
CGZ53_RS05610	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGZ53_RS05615	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGZ53_RS05615	COG0022	dehydrogenase e1 component
CGZ53_RS05620	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CGZ53_RS05625	COG0488	(ABC) transporter
CGZ53_RS05645	COG3842	ATPase activity
CGZ53_RS05660	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CGZ53_RS05665	COG3527	Alpha-acetolactate decarboxylase
CGZ53_RS05670	COG0028	Belongs to the TPP enzyme family
CGZ53_RS05675	COG0457	Tetratricopeptide repeat
CGZ53_RS05680	COG0628	permease
CGZ53_RS05685	COG1051	belongs to the nudix hydrolase family
CGZ53_RS05690	COG2706	6-phosphogluconolactonase activity
CGZ53_RS05705	COG1088	dTDP-glucose 4,6-dehydratase activity
CGZ53_RS05715	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CGZ53_RS05720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGZ53_RS05740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CGZ53_RS05750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CGZ53_RS05755	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CGZ53_RS05755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CGZ53_RS05760	COG0300	oxidoreductase activity
CGZ53_RS05765	COG1234	tRNA 3'-trailer cleavage
CGZ53_RS05770	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CGZ53_RS05775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CGZ53_RS05780	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CGZ53_RS05800	COG1054	Belongs to the UPF0176 family
CGZ53_RS05810	COG0058	SHG alpha-glucan phosphorylase activity
CGZ53_RS05815	COG1640	4-alpha-glucanotransferase
CGZ53_RS05820	COG1609	Transcriptional regulator
CGZ53_RS05830	COG1175	transmembrane transport
CGZ53_RS05835	COG3833	ABC-type maltose transport systems, permease component
CGZ53_RS05840	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CGZ53_RS05845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CGZ53_RS05850	COG1696	Membrane protein involved in D-alanine export
CGZ53_RS05865	COG0556	nucleotide-excision repair
CGZ53_RS05870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGZ53_RS05875	COG1126	abc transporter atp-binding protein
CGZ53_RS05895	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CGZ53_RS05905	COG2309	aminopeptidase activity
CGZ53_RS05915	COG1187	pseudouridine synthase activity
CGZ53_RS05930	COG2814	Major facilitator Superfamily
CGZ53_RS05935	COG4868	Belongs to the UPF0371 family
CGZ53_RS05940	COG0390	transport system, permease component
CGZ53_RS05945	COG4619	ABC transporter
CGZ53_RS05965	COG2274	protein secretion by the type I secretion system
CGZ53_RS05980	COG1131	(ABC) transporter
CGZ53_RS06020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CGZ53_RS06030	COG0024	Methionine aminopeptidase
CGZ53_RS06035	COG4109	DRTGG domain
CGZ53_RS06065	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ53_RS06070	COG1312	Catalyzes the dehydration of D-mannonate
CGZ53_RS06075	COG1904	glucuronate isomerase
CGZ53_RS06080	COG0800	Aldolase
CGZ53_RS06085	COG2186	Transcriptional regulator
CGZ53_RS06090	COG3250	beta-galactosidase activity
CGZ53_RS06100	COG2211	Major facilitator Superfamily
CGZ53_RS06110	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CGZ53_RS06130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CGZ53_RS06135	COG1956	GAF domain-containing protein
CGZ53_RS06145	COG0572	uridine kinase
CGZ53_RS06150	COG0513	Belongs to the DEAD box helicase family
CGZ53_RS06155	COG0726	polysaccharide deacetylase
CGZ53_RS06170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGZ53_RS06175	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CGZ53_RS06180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGZ53_RS06185	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGZ53_RS06205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CGZ53_RS06210	COG4122	O-methyltransferase activity
CGZ53_RS06215	COG2223	nitrite transmembrane transporter activity
CGZ53_RS06240	COG1187	pseudouridine synthase activity
CGZ53_RS06245	COG0363	glucosamine-6-phosphate deaminase activity
CGZ53_RS06270	COG2333	competence protein COMEC
CGZ53_RS06270	COG0658	competence protein
CGZ53_RS06275	COG0322	excinuclease ABC activity
CGZ53_RS06280	COG0204	Acyl-transferase
CGZ53_RS06285	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CGZ53_RS06300	COG0513	Belongs to the DEAD box helicase family
CGZ53_RS06305	COG0561	phosphatase activity
CGZ53_RS06315	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CGZ53_RS06325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CGZ53_RS06335	COG1181	Belongs to the D-alanine--D-alanine ligase family
CGZ53_RS06340	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CGZ53_RS06345	COG0768	penicillin binding
CGZ53_RS06350	COG2116	formate transmembrane transporter activity
CGZ53_RS06360	COG1827	regulation of RNA biosynthetic process
CGZ53_RS06365	COG0588	phosphoglycerate mutase activity
CGZ53_RS06370	COG0167	dihydroorotate dehydrogenase activity
CGZ53_RS06380	COG2217	Heavy metal translocating P-type atpase
CGZ53_RS06395	COG2755	lipolytic protein G-D-S-L family
CGZ53_RS06405	COG0497	DNA recombination
CGZ53_RS06415	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CGZ53_RS06425	COG1722	exodeoxyribonuclease VII activity
CGZ53_RS06430	COG1570	exodeoxyribonuclease VII activity
CGZ53_RS06435	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CGZ53_RS06440	COG1126	abc transporter atp-binding protein
CGZ53_RS06445	COG0765	amino acid transport
CGZ53_RS06455	COG0542	response to heat
CGZ53_RS06460	COG0494	nUDIX hydrolase
CGZ53_RS06475	COG3599	regulation of cell shape
CGZ53_RS06490	COG1799	cell septum assembly
CGZ53_RS06495	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CGZ53_RS06515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CGZ53_RS06520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CGZ53_RS06530	COG1217	gtp-binding protein TYPA
CGZ53_RS06540	COG1940	carbohydrate kinase activity
CGZ53_RS06555	COG1132	(ABC) transporter
CGZ53_RS06560	COG1132	(ABC) transporter
CGZ53_RS06570	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CGZ53_RS06575	COG4470	Protein conserved in bacteria
CGZ53_RS06580	COG0737	Belongs to the 5'-nucleotidase family
CGZ53_RS06585	COG1879	ABC-type sugar transport system periplasmic component
CGZ53_RS06590	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGZ53_RS06600	COG1869	D-ribose catabolic process
CGZ53_RS06605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGZ53_RS06610	COG1609	Transcriptional regulator
CGZ53_RS06615	COG3480	Lon protease (S16) C-terminal proteolytic domain
CGZ53_RS06620	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CGZ53_RS06625	COG0742	ribosomal rna small subunit methyltransferase
CGZ53_RS06630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CGZ53_RS06650	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CGZ53_RS06655	COG1982	Orn Lys Arg decarboxylase major
CGZ53_RS06660	COG2502	aspartate--ammonia ligase
CGZ53_RS06665	COG0549	Belongs to the carbamate kinase family
CGZ53_RS06670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CGZ53_RS06675	COG1288	antiporter activity
CGZ53_RS06680	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CGZ53_RS06685	COG2235	arginine
CGZ53_RS06705	COG2315	Protein conserved in bacteria
CGZ53_RS06720	COG0494	nUDIX hydrolase
CGZ53_RS06760	COG0110	maltose O-acetyltransferase activity
CGZ53_RS06805	COG0561	phosphatase activity
CGZ53_RS06815	COG4152	abc transporter atp-binding protein
CGZ53_RS06820	COG1668	transmembrane transport
CGZ53_RS06825	COG0586	Pfam SNARE associated Golgi protein
CGZ53_RS06835	COG3976	FMN-binding domain protein
CGZ53_RS06835	COG1053	succinate dehydrogenase
CGZ53_RS06835	COG0431	NADPH-dependent FMN reductase
CGZ53_RS06840	COG0710	3-dehydroquinate dehydratase activity
CGZ53_RS06845	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CGZ53_RS06850	COG2814	Major facilitator Superfamily
CGZ53_RS06855	COG2271	Major facilitator Superfamily
CGZ53_RS06860	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ53_RS06870	COG0583	DNA-binding transcription factor activity
CGZ53_RS06880	COG1247	-acetyltransferase
CGZ53_RS06895	COG2137	regulation of response to DNA damage stimulus
CGZ53_RS06900	COG3557	Belongs to the UPF0374 family
CGZ53_RS06970	COG1040	competence protein
CGZ53_RS06975	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CGZ53_RS06980	COG1739	Uncharacterized protein family UPF0029
CGZ53_RS06990	COG1098	S1 RNA binding domain
CGZ53_RS07000	COG2197	response regulator
CGZ53_RS07005	COG4585	Histidine kinase
CGZ53_RS07015	COG0515	serine threonine protein kinase
CGZ53_RS07015	COG2815	serine threonine protein kinase
CGZ53_RS07025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CGZ53_RS07025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CGZ53_RS07030	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CGZ53_RS07035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CGZ53_RS07040	COG1758	RNA polymerase activity
CGZ53_RS07055	COG0583	DNA-binding transcription factor activity
CGZ53_RS07060	COG0183	Belongs to the thiolase family
CGZ53_RS07065	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CGZ53_RS07075	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ53_RS07080	COG2610	gluconate transmembrane transporter activity
CGZ53_RS07085	COG1854	S-ribosylhomocysteine lyase activity
CGZ53_RS07105	COG0116	Belongs to the methyltransferase superfamily
CGZ53_RS07115	COG3599	regulation of cell shape
CGZ53_RS07120	COG4474	Belongs to the UPF0398 family
CGZ53_RS07125	COG3331	DNA recombination
CGZ53_RS07130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGZ53_RS07135	COG3579	cysteine-type endopeptidase activity
CGZ53_RS07140	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CGZ53_RS07145	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CGZ53_RS07150	COG1113	amino acid transport
CGZ53_RS07155	COG0492	ferredoxin-NADP+ reductase activity
CGZ53_RS07165	COG1126	abc transporter atp-binding protein
CGZ53_RS07170	COG0765	amino acid transport
CGZ53_RS07175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGZ53_RS07180	COG0513	Belongs to the DEAD box helicase family
CGZ53_RS07185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CGZ53_RS07190	COG0768	penicillin binding
CGZ53_RS07200	COG0275	rRNA processing
CGZ53_RS07205	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CGZ53_RS07210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CGZ53_RS07220	COG1131	(ABC) transporter
CGZ53_RS07245	COG0446	pyridine nucleotide-disulphide oxidoreductase
CGZ53_RS07250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CGZ53_RS07260	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CGZ53_RS07270	COG0751	glycine-tRNA ligase activity
CGZ53_RS07275	COG0752	glycyl-tRNA synthetase alpha subunit
CGZ53_RS07285	COG1755	Isoprenylcysteine carboxyl methyltransferase
CGZ53_RS07325	COG0561	phosphatase activity
CGZ53_RS07345	COG3711	transcriptional antiterminator
CGZ53_RS07360	COG1105	Belongs to the carbohydrate kinase PfkB family
CGZ53_RS07365	COG0698	ribose 5-phosphate isomerase
CGZ53_RS07370	COG0698	ribose 5-phosphate isomerase
CGZ53_RS07375	COG3775	system Galactitol-specific IIC component
CGZ53_RS07385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGZ53_RS07400	COG2217	Heavy metal translocating P-type atpase
CGZ53_RS07410	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CGZ53_RS07415	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CGZ53_RS07425	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CGZ53_RS07430	COG0195	Participates in both transcription termination and antitermination
CGZ53_RS07435	COG0779	Required for maturation of 30S ribosomal subunits
CGZ53_RS07445	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CGZ53_RS07455	COG4473	ABC transporter
CGZ53_RS07460	COG1131	(ABC) transporter
CGZ53_RS07465	COG0537	adenosine 5'-monophosphoramidase activity
CGZ53_RS07475	COG1316	TRANSCRIPTIONal
CGZ53_RS07485	COG0802	atpase or kinase
CGZ53_RS07490	COG2252	PERMEase
CGZ53_RS07495	COG0561	phosphatase activity
CGZ53_RS07505	COG3715	PTS system
CGZ53_RS07510	COG3716	PTS system mannose fructose sorbose family IID component
CGZ53_RS07525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CGZ53_RS07530	COG0825	malonyl-CoA metabolic process
CGZ53_RS07540	COG0439	Biotin carboxylase
CGZ53_RS07545	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CGZ53_RS07555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CGZ53_RS07560	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ53_RS07565	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CGZ53_RS07570	COG2070	2-Nitropropane dioxygenase
CGZ53_RS07580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGZ53_RS07590	COG1024	Enoyl-CoA hydratase
CGZ53_RS07595	COG0484	heat shock protein binding
CGZ53_RS07600	COG0443	Heat shock 70 kDa protein
CGZ53_RS07610	COG1420	regulation of RNA biosynthetic process
CGZ53_RS07615	COG3942	CHAP domain
CGZ53_RS07615	COG1705	Flagellar rod assembly protein muramidase FlgJ
CGZ53_RS07625	COG0588	phosphoglycerate mutase activity
CGZ53_RS07635	COG2848	UPF0210 protein
CGZ53_RS07640	COG3830	Belongs to the UPF0237 family
CGZ53_RS07650	COG2261	transglycosylase associated protein
CGZ53_RS07655	COG0697	spore germination
CGZ53_RS07660	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CGZ53_RS07665	COG0154	amidase activity
CGZ53_RS07670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CGZ53_RS07675	COG0574	Belongs to the PEP-utilizing enzyme family
CGZ53_RS07675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGZ53_RS07680	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CGZ53_RS07685	COG0517	IMP dehydrogenase activity
CGZ53_RS07695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CGZ53_RS07695	COG0425	Belongs to the sulfur carrier protein TusA family
CGZ53_RS07700	COG0446	pyridine nucleotide-disulphide oxidoreductase
CGZ53_RS07710	COG1937	Protein conserved in bacteria
CGZ53_RS07715	COG1335	isochorismatase
CGZ53_RS07720	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CGZ53_RS07725	COG0436	Aminotransferase
CGZ53_RS07730	COG0589	response to stress
CGZ53_RS07735	COG0561	phosphatase activity
CGZ53_RS07990	COG0582	viral genome integration into host DNA
CGZ53_RS07995	COG0252	asparaginase activity
CGZ53_RS08000	COG4989	oxidoreductase activity
CGZ53_RS08005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CGZ53_RS08010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CGZ53_RS08015	COG0736	holo-[acyl-carrier-protein] synthase activity
CGZ53_RS08020	COG0653	protein targeting
CGZ53_RS08025	COG1482	cell wall glycoprotein biosynthetic process
CGZ53_RS08030	COG2723	6-phospho-beta-galactosidase activity
CGZ53_RS08035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CGZ53_RS08045	COG1940	carbohydrate kinase activity
CGZ53_RS08050	COG2190	(PTS) system
CGZ53_RS08050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGZ53_RS08050	COG1263	PTS System
CGZ53_RS08055	COG1621	beta-fructofuranosidase activity
CGZ53_RS08060	COG1609	Transcriptional regulator
CGZ53_RS08065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CGZ53_RS08075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CGZ53_RS08080	COG2131	deaminase
CGZ53_RS08085	COG0006	proline dipeptidase activity
CGZ53_RS08115	COG0360	Binds together with S18 to 16S ribosomal RNA
CGZ53_RS08120	COG1194	a g-specific adenine glycosylase
CGZ53_RS08125	COG3118	belongs to the thioredoxin family
CGZ53_RS08130	COG1193	negative regulation of DNA recombination
CGZ53_RS08145	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CGZ53_RS08150	COG0681	Belongs to the peptidase S26 family
CGZ53_RS08155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CGZ53_RS08170	COG1882	Formate acetyltransferase
CGZ53_RS08180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CGZ53_RS08195	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CGZ53_RS08200	COG2936	dipeptidyl-peptidase activity
CGZ53_RS08225	COG2723	6-phospho-beta-galactosidase activity
CGZ53_RS08240	COG1737	Transcriptional regulator
CGZ53_RS08270	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CGZ53_RS08285	COG2081	HI0933 family
CGZ53_RS08295	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CGZ53_RS08305	COG1214	PFAM Peptidase M22, glycoprotease
CGZ53_RS08310	COG5503	Protein of unknown function (DUF1447)
CGZ53_RS08320	COG4608	Belongs to the ABC transporter superfamily
CGZ53_RS08325	COG0444	Belongs to the ABC transporter superfamily
CGZ53_RS08330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGZ53_RS08335	COG0601	transmembrane transport
CGZ53_RS08340	COG4166	transmembrane transport
CGZ53_RS08345	COG0174	glutamine synthetase
CGZ53_RS08350	COG0789	Transcriptional regulator
CGZ53_RS08360	COG0126	phosphoglycerate kinase activity
CGZ53_RS08370	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CGZ53_RS08375	COG0049	tRNA binding
CGZ53_RS08380	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CGZ53_RS08390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CGZ53_RS08395	COG3481	metal-dependent phosphohydrolase, HD sub domain
CGZ53_RS08405	COG1564	THIamine pyrophosphokinase
CGZ53_RS08420	COG2814	Major facilitator Superfamily
CGZ53_RS08430	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CGZ53_RS08445	COG0084	hydrolase, TatD family'
CGZ53_RS08455	COG3458	cephalosporin-C deacetylase activity
CGZ53_RS08465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGZ53_RS08480	COG0395	ABC-type sugar transport system, permease component
CGZ53_RS08490	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CGZ53_RS08520	COG1131	(ABC) transporter
CGZ53_RS08535	COG0594	ribonuclease P activity
CGZ53_RS08540	COG0165	Argininosuccinate lyase
CGZ53_RS08545	COG0137	argininosuccinate synthase activity
CGZ53_RS08600	COG0756	dUTP diphosphatase activity
CGZ53_RS08605	COG2832	Protein of unknown function (DUF454)
CGZ53_RS08625	COG1132	(ABC) transporter
CGZ53_RS08630	COG1132	(ABC) transporter
CGZ53_RS08640	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CGZ53_RS08645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CGZ53_RS08655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CGZ53_RS08660	COG0534	Mate efflux family protein
CGZ53_RS08665	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CGZ53_RS08675	COG1473	amidohydrolase
CGZ53_RS08680	COG2171	N-acyltransferase activity
CGZ53_RS08690	COG3732	PTS system glucitol sorbitol-specific
CGZ53_RS08695	COG3730	PTS system glucitol sorbitol-specific
CGZ53_RS08705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGZ53_RS08705	COG3711	transcriptional antiterminator
CGZ53_RS08715	COG0166	Belongs to the GPI family
CGZ53_RS08730	COG1234	tRNA 3'-trailer cleavage
CGZ53_RS08735	COG1268	BioY protein
CGZ53_RS08745	COG0343	queuine tRNA-ribosyltransferase activity
CGZ53_RS08760	COG1832	CoA-binding protein
CGZ53_RS08765	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CGZ53_RS08765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CGZ53_RS08775	COG4175	Glycine betaine
CGZ53_RS08775	COG3448	diguanylate cyclase activity
CGZ53_RS08780	COG1597	lipid kinase activity
CGZ53_RS08800	COG3623	hexulose-6-phosphate isomerase
CGZ53_RS08810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGZ53_RS08820	COG3037	sugar-specific permease SgaT UlaA
CGZ53_RS08830	COG0495	leucyl-tRNA aminoacylation
CGZ53_RS08855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGZ53_RS08870	COG0564	pseudouridine synthase activity
CGZ53_RS08895	COG0459	protein refolding
CGZ53_RS08900	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CGZ53_RS08905	COG0542	response to heat
CGZ53_RS08910	COG4463	regulation of RNA biosynthetic process
CGZ53_RS08930	COG0346	lactoylglutathione lyase activity
CGZ53_RS08935	COG0346	lactoylglutathione lyase activity
CGZ53_RS08940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CGZ53_RS08945	COG0400	carboxylic ester hydrolase activity
CGZ53_RS08955	COG0450	alkyl hydroperoxide reductase
CGZ53_RS08960	COG3634	alkyl hydroperoxide reductase activity
CGZ53_RS08965	COG0052	Belongs to the universal ribosomal protein uS2 family
CGZ53_RS08970	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CGZ53_RS08975	COG3590	peptidase
CGZ53_RS08980	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CGZ53_RS08985	COG3959	Transketolase, thiamine diphosphate binding domain
CGZ53_RS09000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGZ53_RS09005	COG0366	Alpha amylase catalytic
CGZ53_RS09010	COG1263	PTS System
CGZ53_RS09010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGZ53_RS09015	COG2188	Transcriptional regulator
CGZ53_RS09020	COG1733	regulation of RNA biosynthetic process
CGZ53_RS09025	COG2514	catechol 2,3-dioxygenase activity
CGZ53_RS09030	COG3022	response to hydroperoxide
CGZ53_RS09035	COG0602	queuosine metabolic process
CGZ53_RS09050	COG1328	CTP reductase activity
CGZ53_RS09065	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CGZ53_RS09070	COG4472	Bacterial protein of unknown function (DUF965)
CGZ53_RS09075	COG1393	Belongs to the ArsC family
CGZ53_RS09080	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CGZ53_RS09085	COG1058	Belongs to the CinA family
CGZ53_RS09085	COG1546	Belongs to the CinA family
CGZ53_RS09090	COG0519	Catalyzes the synthesis of GMP from XMP
CGZ53_RS09095	COG0632	four-way junction helicase activity
CGZ53_RS09105	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CGZ53_RS09120	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CGZ53_RS09135	COG0018	arginyl-trna synthetase
CGZ53_RS09140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CGZ53_RS09150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CGZ53_RS09155	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CGZ53_RS09160	COG0124	histidyl-tRNA synthetase
CGZ53_RS09165	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CGZ53_RS09195	COG2508	Transcriptional regulator
CGZ53_RS09205	COG0318	PFAM AMP-dependent synthetase and ligase
CGZ53_RS09210	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGZ53_RS09215	COG0183	Belongs to the thiolase family
CGZ53_RS09220	COG1960	acyl-CoA dehydrogenase activity
CGZ53_RS09225	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGZ53_RS09235	COG0701	Predicted permease
CGZ53_RS09265	COG3759	membrane
CGZ53_RS09270	COG1511	domain protein
CGZ53_RS09280	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CGZ53_RS09290	COG0305	Participates in initiation and elongation during chromosome replication
CGZ53_RS09295	COG0359	binds to the 23S rRNA
CGZ53_RS09310	COG0482	sulfurtransferase activity
CGZ53_RS09315	COG1760	l-serine dehydratase
CGZ53_RS09320	COG1760	l-serine dehydratase
CGZ53_RS09330	COG0741	lytic transglycosylase activity
CGZ53_RS09335	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CGZ53_RS09350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CGZ53_RS09360	COG0612	Peptidase, M16
CGZ53_RS09375	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CGZ53_RS09385	COG0516	GMP reductase activity
CGZ53_RS09385	COG0517	IMP dehydrogenase activity
CGZ53_RS09395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CGZ53_RS09400	COG0488	(ABC) transporter
CGZ53_RS09425	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CGZ53_RS09430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGZ53_RS09435	COG1475	DNA binding