locus-tag	class	description
DMT42_RS00080	COG1733	regulation of RNA biosynthetic process
DMT42_RS00085	COG0702	epimerase
DMT42_RS00155	COG1846	Transcriptional regulator
DMT42_RS00235	COG2318	DinB family
DMT42_RS00250	COG2770	Histidine kinase
DMT42_RS00250	COG2208	phosphoserine phosphatase activity
DMT42_RS00275	COG2910	NAD(P)H-binding
DMT42_RS00280	COG1733	regulation of RNA biosynthetic process
DMT42_RS00325	COG1846	Transcriptional regulator
DMT42_RS00330	COG2409	Drug exporters of the RND superfamily
DMT42_RS00345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DMT42_RS00355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMT42_RS00360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMT42_RS00370	COG0477	Major facilitator Superfamily
DMT42_RS00395	COG0494	nUDIX hydrolase
DMT42_RS00415	COG3844	kynureninase activity
DMT42_RS00425	COG3483	tryptophan 2,3-dioxygenase activity
DMT42_RS00430	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS00440	COG2151	metal-sulfur cluster biosynthetic enzyme
DMT42_RS00445	COG3396	Phenylacetate-CoA oxygenase
DMT42_RS00480	COG0604	alcohol dehydrogenase
DMT42_RS00490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DMT42_RS00495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DMT42_RS00515	COG2814	Major facilitator Superfamily
DMT42_RS00525	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DMT42_RS00550	COG1522	sequence-specific DNA binding
DMT42_RS00605	COG4221	oxidoreductase activity
DMT42_RS00610	COG0671	phosphoesterase, PA-phosphatase related
DMT42_RS00615	COG1295	ribonuclease BN
DMT42_RS00635	COG0583	DNA-binding transcription factor activity
DMT42_RS00650	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DMT42_RS00670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DMT42_RS00675	COG0367	asparagine synthase
DMT42_RS00700	COG4977	sequence-specific DNA binding
DMT42_RS00705	COG0793	Belongs to the peptidase S41A family
DMT42_RS00735	COG2197	response regulator
DMT42_RS00740	COG2205	protein histidine kinase activity
DMT42_RS00780	COG1940	carbohydrate kinase activity
DMT42_RS00790	COG4214	carbohydrate transport
DMT42_RS00795	COG4213	ABC transporter substrate-binding protein
DMT42_RS00815	COG1231	oxidoreductase activity
DMT42_RS00825	COG2409	Drug exporters of the RND superfamily
DMT42_RS00830	COG3903	Transcriptional regulator
DMT42_RS00830	COG3629	intracellular signal transduction
DMT42_RS00835	COG1309	transcriptional regulator
DMT42_RS00850	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DMT42_RS00850	COG2050	protein possibly involved in aromatic compounds catabolism
DMT42_RS00860	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS00865	COG2814	Major facilitator Superfamily
DMT42_RS00885	COG0318	PFAM AMP-dependent synthetase and ligase
DMT42_RS00910	COG0513	Belongs to the DEAD box helicase family
DMT42_RS00980	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DMT42_RS00980	COG2308	Evidence 4 Homologs of previously reported genes of
DMT42_RS00985	COG0367	asparagine synthase
DMT42_RS01010	COG5640	endopeptidase activity
DMT42_RS01015	COG0583	DNA-binding transcription factor activity
DMT42_RS01020	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DMT42_RS01075	COG1846	Transcriptional regulator
DMT42_RS01085	COG2208	phosphoserine phosphatase activity
DMT42_RS01085	COG2770	Histidine kinase
DMT42_RS01095	COG1271	oxidase subunit
DMT42_RS01170	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DMT42_RS01215	COG1595	DNA-templated transcription, initiation
DMT42_RS01255	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DMT42_RS01260	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DMT42_RS01280	COG0673	inositol 2-dehydrogenase activity
DMT42_RS01285	COG2814	Major facilitator Superfamily
DMT42_RS01310	COG3345	alpha-galactosidase
DMT42_RS01325	COG1335	isochorismatase
DMT42_RS01330	COG2132	Multicopper oxidase
DMT42_RS01355	COG0667	Aldo Keto reductase
DMT42_RS01370	COG0604	alcohol dehydrogenase
DMT42_RS01405	COG0121	glutamine amidotransferase
DMT42_RS01420	COG3387	PFAM Glycoside hydrolase 15-related
DMT42_RS01435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DMT42_RS01505	COG1082	Xylose isomerase domain protein TIM barrel
DMT42_RS01535	COG3387	PFAM Glycoside hydrolase 15-related
DMT42_RS01545	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS01580	COG0789	Transcriptional regulator
DMT42_RS01585	COG0395	ABC-type sugar transport system, permease component
DMT42_RS01590	COG1175	transmembrane transport
DMT42_RS01640	COG4977	sequence-specific DNA binding
DMT42_RS01645	COG0366	Alpha amylase catalytic
DMT42_RS01645	COG1874	Beta-galactosidase
DMT42_RS01690	COG1132	(ABC) transporter
DMT42_RS01715	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DMT42_RS01715	COG1672	PFAM Archaeal ATPase
DMT42_RS01730	COG3766	membrane
DMT42_RS01735	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DMT42_RS01750	COG2234	aminopeptidase activity
DMT42_RS01750	COG4935	Belongs to the peptidase S8 family
DMT42_RS01760	COG0300	oxidoreductase activity
DMT42_RS01770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DMT42_RS01790	COG2267	carboxylic ester hydrolase activity
DMT42_RS01800	COG0477	Major facilitator Superfamily
DMT42_RS01815	COG2208	phosphoserine phosphatase activity
DMT42_RS01815	COG2770	Histidine kinase
DMT42_RS01820	COG0596	Alpha beta hydrolase
DMT42_RS01825	COG2070	2-Nitropropane dioxygenase
DMT42_RS01835	COG0789	Transcriptional regulator
DMT42_RS01845	COG3795	YCII-related domain
DMT42_RS01850	COG4941	Belongs to the sigma-70 factor family
DMT42_RS01870	COG0596	Alpha beta hydrolase
DMT42_RS01875	COG3629	intracellular signal transduction
DMT42_RS01875	COG3903	Transcriptional regulator
DMT42_RS01880	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DMT42_RS01885	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMT42_RS01890	COG0395	ABC-type sugar transport system, permease component
DMT42_RS01895	COG1175	transmembrane transport
DMT42_RS01900	COG2182	Extracellular solute-binding protein
DMT42_RS01915	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS01995	COG4977	sequence-specific DNA binding
DMT42_RS02045	COG0714	Associated with various cellular activities
DMT42_RS02050	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DMT42_RS02090	COG0318	PFAM AMP-dependent synthetase and ligase
DMT42_RS02095	COG2508	Transcriptional regulator
DMT42_RS02190	COG2814	Major facilitator Superfamily
DMT42_RS02205	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DMT42_RS02210	COG0477	Major facilitator Superfamily
DMT42_RS02215	COG1846	Transcriptional regulator
DMT42_RS02250	COG1175	transmembrane transport
DMT42_RS02255	COG0395	ABC-type sugar transport system, permease component
DMT42_RS02260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DMT42_RS02275	COG0477	Major facilitator Superfamily
DMT42_RS02305	COG3739	integral membrane protein
DMT42_RS02335	COG1088	dTDP-glucose 4,6-dehydratase activity
DMT42_RS02400	COG2124	cytochrome p450
DMT42_RS02410	COG0009	L-threonylcarbamoyladenylate synthase
DMT42_RS02435	COG0726	polysaccharide deacetylase
DMT42_RS02440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DMT42_RS02450	COG1175	transmembrane transport
DMT42_RS02455	COG0395	ABC-type sugar transport system, permease component
DMT42_RS02465	COG1609	Transcriptional regulator
DMT42_RS02475	COG0667	Aldo Keto reductase
DMT42_RS02480	COG1793	dna ligase
DMT42_RS02480	COG3285	dna ligase
DMT42_RS02510	COG1793	dna ligase
DMT42_RS02535	COG0181	hydroxymethylbilane synthase activity
DMT42_RS02575	COG0366	Alpha amylase catalytic
DMT42_RS02585	COG3281	Trehalose synthase
DMT42_RS02590	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DMT42_RS02595	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DMT42_RS02615	COG1366	Belongs to the anti-sigma-factor antagonist family
DMT42_RS02655	COG1982	Orn Lys Arg decarboxylase major
DMT42_RS02665	COG0477	Major facilitator Superfamily
DMT42_RS02680	COG0583	DNA-binding transcription factor activity
DMT42_RS02700	COG3189	MarR family transcriptional regulator
DMT42_RS02725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMT42_RS02745	COG0492	ferredoxin-NADP+ reductase activity
DMT42_RS02760	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DMT42_RS02760	COG1672	PFAM Archaeal ATPase
DMT42_RS02780	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS02795	COG0142	geranyltranstransferase activity
DMT42_RS02800	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMT42_RS02800	COG0515	serine threonine protein kinase
DMT42_RS02825	COG0667	Aldo Keto reductase
DMT42_RS02860	COG0328	RNA-DNA hybrid ribonuclease activity
DMT42_RS02880	COG0740	serine-type endopeptidase activity
DMT42_RS02885	COG0740	serine-type endopeptidase activity
DMT42_RS02890	COG1396	sequence-specific DNA binding
DMT42_RS02895	COG1191	sigma factor activity
DMT42_RS02925	COG1131	(ABC) transporter
DMT42_RS02925	COG1716	ATPase activity
DMT42_RS02925	COG0842	Transport permease protein
DMT42_RS02935	COG0667	Aldo Keto reductase
DMT42_RS02940	COG0583	DNA-binding transcription factor activity
DMT42_RS02950	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DMT42_RS02955	COG0346	lactoylglutathione lyase activity
DMT42_RS02980	COG3568	Endonuclease Exonuclease Phosphatase
DMT42_RS02990	COG1012	belongs to the aldehyde dehydrogenase family
DMT42_RS02995	COG4941	Belongs to the sigma-70 factor family
DMT42_RS03005	COG0702	epimerase
DMT42_RS03055	COG2267	carboxylic ester hydrolase activity
DMT42_RS03065	COG0673	inositol 2-dehydrogenase activity
DMT42_RS03100	COG0589	response to stress
DMT42_RS03135	COG0318	PFAM AMP-dependent synthetase and ligase
DMT42_RS03140	COG2366	antibiotic biosynthetic process
DMT42_RS03150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DMT42_RS03175	COG0515	serine threonine protein kinase
DMT42_RS03195	COG0142	geranyltranstransferase activity
DMT42_RS03210	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DMT42_RS03290	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DMT42_RS03315	COG2271	Major facilitator Superfamily
DMT42_RS03335	COG1902	pentaerythritol trinitrate reductase activity
DMT42_RS03355	COG0366	Alpha amylase catalytic
DMT42_RS03395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DMT42_RS03410	COG0179	Fumarylacetoacetate (FAA) hydrolase
DMT42_RS03425	COG1621	beta-fructofuranosidase activity
DMT42_RS03445	COG1609	Transcriptional regulator
DMT42_RS03460	COG2376	Dihydroxyacetone kinase
DMT42_RS03465	COG1461	Dihydroxyacetone kinase
DMT42_RS03495	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMT42_RS03495	COG1902	pentaerythritol trinitrate reductase activity
DMT42_RS03520	COG2890	protein-(glutamine-N5) methyltransferase activity
DMT42_RS03545	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DMT42_RS03560	COG3458	cephalosporin-C deacetylase activity
DMT42_RS03565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DMT42_RS03570	COG2188	Transcriptional regulator
DMT42_RS03595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DMT42_RS03605	COG1686	Belongs to the peptidase S11 family
DMT42_RS03615	COG2066	Belongs to the glutaminase family
DMT42_RS03630	COG1113	amino acid transport
DMT42_RS03635	COG2186	Transcriptional regulator
DMT42_RS03640	COG1968	undecaprenyl-diphosphatase activity
DMT42_RS03645	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DMT42_RS03650	COG1993	acr, cog1993
DMT42_RS03655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DMT42_RS03685	COG1653	transport
DMT42_RS03690	COG1175	transmembrane transport
DMT42_RS03695	COG0395	ABC-type sugar transport system, permease component
DMT42_RS03710	COG1846	Transcriptional regulator
DMT42_RS03750	COG4122	O-methyltransferase activity
DMT42_RS03770	COG1349	DNA-binding transcription factor activity
DMT42_RS03780	COG0494	nUDIX hydrolase
DMT42_RS03790	COG0366	Alpha amylase catalytic
DMT42_RS03795	COG0395	ABC-type sugar transport system, permease component
DMT42_RS03800	COG1175	transmembrane transport
DMT42_RS03805	COG1653	transport
DMT42_RS03850	COG1408	metallophosphoesterase
DMT42_RS03865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DMT42_RS03870	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DMT42_RS03935	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS03965	COG1215	transferase activity, transferring glycosyl groups
DMT42_RS04010	COG1349	DNA-binding transcription factor activity
DMT42_RS04030	COG0577	efflux transmembrane transporter activity
DMT42_RS04070	COG2084	Dehydrogenase
DMT42_RS04075	COG1309	transcriptional regulator
DMT42_RS04080	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS04085	COG1940	carbohydrate kinase activity
DMT42_RS04095	COG2813	Specifically methylates the guanine in position
DMT42_RS04100	COG0191	fructose-bisphosphate aldolase activity
DMT42_RS04105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DMT42_RS04110	COG1349	DNA-binding transcription factor activity
DMT42_RS04115	COG3387	PFAM Glycoside hydrolase 15-related
DMT42_RS04140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DMT42_RS04145	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DMT42_RS04150	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DMT42_RS04155	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DMT42_RS04155	COG1796	DNA polymerase
DMT42_RS04175	COG0326	Molecular chaperone. Has ATPase activity
DMT42_RS04180	COG1473	amidohydrolase
DMT42_RS04190	COG1309	transcriptional regulator
DMT42_RS04220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DMT42_RS04225	COG2151	metal-sulfur cluster biosynthetic enzyme
DMT42_RS04230	COG3396	Phenylacetate-CoA oxygenase
DMT42_RS04235	COG3460	Phenylacetate-CoA oxygenase
DMT42_RS04240	COG3396	Phenylacetate-CoA oxygenase
DMT42_RS04245	COG2188	Transcriptional regulator
DMT42_RS04255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DMT42_RS04260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMT42_RS04270	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DMT42_RS04285	COG0477	Major facilitator Superfamily
DMT42_RS04290	COG3973	AAA domain
DMT42_RS04315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMT42_RS04320	COG0738	Major facilitator superfamily
DMT42_RS04365	COG2197	response regulator
DMT42_RS04370	COG4585	Histidine kinase
DMT42_RS04400	COG0789	Transcriptional regulator
DMT42_RS04410	COG1660	Displays ATPase and GTPase activities
DMT42_RS04430	COG3345	alpha-galactosidase
DMT42_RS04460	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DMT42_RS04485	COG0204	Acyl-transferase
DMT42_RS04495	COG0583	DNA-binding transcription factor activity
DMT42_RS04520	COG0584	glycerophosphoryl diester phosphodiesterase
DMT42_RS04540	COG0667	Aldo Keto reductase
DMT42_RS04555	COG1215	transferase activity, transferring glycosyl groups
DMT42_RS04585	COG0671	phosphoesterase, PA-phosphatase related
DMT42_RS04590	COG0456	acetyltransferase
DMT42_RS04600	COG1309	transcriptional regulator
DMT42_RS04630	COG0640	Transcriptional regulator
DMT42_RS04640	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DMT42_RS04650	COG3509	depolymerase
DMT42_RS04665	COG1960	acyl-CoA dehydrogenase activity
DMT42_RS04680	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DMT42_RS04760	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DMT42_RS04765	COG1733	regulation of RNA biosynthetic process
DMT42_RS04780	COG0432	Pfam Uncharacterised protein family UPF0047
DMT42_RS04785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMT42_RS04790	COG1116	anion transmembrane transporter activity
DMT42_RS04800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMT42_RS04815	COG1132	(ABC) transporter
DMT42_RS04840	COG1132	(ABC) transporter
DMT42_RS04850	COG0254	rRNA binding
DMT42_RS04865	COG1946	Acyl-CoA thioesterase
DMT42_RS04875	COG2018	Roadblock/LC7 domain
DMT42_RS04980	COG1940	carbohydrate kinase activity
DMT42_RS04980	COG1846	Transcriptional regulator
DMT42_RS05025	COG1960	acyl-CoA dehydrogenase activity
DMT42_RS05030	COG1960	acyl-CoA dehydrogenase activity
DMT42_RS05045	COG3634	alkyl hydroperoxide reductase activity
DMT42_RS05050	COG1793	dna ligase
DMT42_RS05055	COG0494	nUDIX hydrolase
DMT42_RS05060	COG1012	belongs to the aldehyde dehydrogenase family
DMT42_RS05070	COG1960	acyl-CoA dehydrogenase activity
DMT42_RS05080	COG0242	peptide deformylase activity
DMT42_RS05090	COG3442	glutamine amidotransferase
DMT42_RS05095	COG0205	6-phosphofructokinase activity
DMT42_RS05110	COG3275	phosphorelay sensor kinase activity
DMT42_RS05115	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMT42_RS05125	COG3279	Response regulator of the LytR AlgR family
DMT42_RS05130	COG1522	sequence-specific DNA binding
DMT42_RS05135	COG1834	amidinotransferase
DMT42_RS05140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DMT42_RS05155	COG0204	Acyl-transferase
DMT42_RS05165	COG0829	nickel cation binding
DMT42_RS05170	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DMT42_RS05175	COG0830	nickel cation binding
DMT42_RS05180	COG0804	urea catabolic process
DMT42_RS05185	COG0832	Belongs to the urease beta subunit family
DMT42_RS05190	COG0831	urea catabolic process
DMT42_RS05200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMT42_RS05205	COG0740	serine-type endopeptidase activity
DMT42_RS05220	COG1280	lysine exporter protein (LysE YggA)
DMT42_RS05225	COG0583	DNA-binding transcription factor activity
DMT42_RS05250	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DMT42_RS05255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DMT42_RS05260	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DMT42_RS05265	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DMT42_RS05275	COG0577	efflux transmembrane transporter activity
DMT42_RS05275	COG1136	(ABC) transporter
DMT42_RS05285	COG0456	acetyltransferase
DMT42_RS05305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DMT42_RS05330	COG4585	Histidine kinase
DMT42_RS05340	COG0326	Molecular chaperone. Has ATPase activity
DMT42_RS05345	COG2197	response regulator
DMT42_RS05350	COG1940	carbohydrate kinase activity
DMT42_RS05380	COG0626	cystathionine gamma-synthase activity
DMT42_RS05400	COG1522	sequence-specific DNA binding
DMT42_RS05405	COG0419	ATPase involved in DNA repair
DMT42_RS05410	COG0420	3'-5' exonuclease activity
DMT42_RS05415	COG1739	Uncharacterized protein family UPF0029
DMT42_RS05430	COG1832	CoA-binding protein
DMT42_RS05435	COG2814	Major facilitator Superfamily
DMT42_RS05445	COG0656	L-ascorbic acid biosynthetic process
DMT42_RS05450	COG0640	Transcriptional regulator
DMT42_RS05475	COG0110	maltose O-acetyltransferase activity
DMT42_RS05495	COG0789	Transcriptional regulator
DMT42_RS05525	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DMT42_RS05555	COG0183	Belongs to the thiolase family
DMT42_RS05575	COG1968	undecaprenyl-diphosphatase activity
DMT42_RS05590	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS05605	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DMT42_RS05625	COG2318	DinB family
DMT42_RS05640	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DMT42_RS05645	COG4166	transmembrane transport
DMT42_RS05685	COG0583	DNA-binding transcription factor activity
DMT42_RS05690	COG0697	spore germination
DMT42_RS05725	COG1695	Transcriptional regulator
DMT42_RS05735	COG0384	phenazine biosynthesis protein PhzF
DMT42_RS05770	COG0725	ABC transporter, periplasmic molybdate-binding protein
DMT42_RS05785	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMT42_RS05785	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMT42_RS05820	COG1716	ATPase activity
DMT42_RS05840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DMT42_RS05870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMT42_RS05885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMT42_RS05890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DMT42_RS05905	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DMT42_RS05915	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DMT42_RS05920	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DMT42_RS05940	COG2018	Roadblock/LC7 domain
DMT42_RS05955	COG1414	Transcriptional regulator
DMT42_RS05980	COG2814	Major facilitator Superfamily
DMT42_RS05985	COG4336	lyase activity
DMT42_RS05990	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DMT42_RS05995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DMT42_RS06000	COG1984	allophanate hydrolase subunit 2
DMT42_RS06030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMT42_RS06035	COG2364	Membrane
DMT42_RS06045	COG2270	Major facilitator Superfamily
DMT42_RS06060	COG1216	Glycosyl transferase, family 2
DMT42_RS06085	COG1960	acyl-CoA dehydrogenase activity
DMT42_RS06090	COG1309	transcriptional regulator
DMT42_RS06130	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DMT42_RS06135	COG0140	phosphoribosyl-ATP diphosphatase activity
DMT42_RS06140	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DMT42_RS06145	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMT42_RS06145	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMT42_RS06150	COG3201	nicotinamide mononucleotide transporter
DMT42_RS06180	COG1940	carbohydrate kinase activity
DMT42_RS06180	COG1846	Transcriptional regulator
DMT42_RS06195	COG2233	PERMEase
DMT42_RS06220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DMT42_RS06240	COG0531	amino acid
DMT42_RS06260	COG2390	Transcriptional regulator
DMT42_RS06265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DMT42_RS06270	COG2409	Drug exporters of the RND superfamily
DMT42_RS06280	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DMT42_RS06295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DMT42_RS06305	COG1758	RNA polymerase activity
DMT42_RS06310	COG0194	GDP metabolic process
DMT42_RS06320	COG0284	orotidine-5'-phosphate decarboxylase activity
DMT42_RS06325	COG0167	dihydroorotate dehydrogenase activity
DMT42_RS06330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DMT42_RS06335	COG0505	Belongs to the CarA family
DMT42_RS06345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DMT42_RS06350	COG0540	Belongs to the ATCase OTCase family
DMT42_RS06355	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DMT42_RS06365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DMT42_RS06370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DMT42_RS06375	COG0006	proline dipeptidase activity
DMT42_RS06385	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DMT42_RS06390	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DMT42_RS06395	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DMT42_RS06400	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DMT42_RS06415	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DMT42_RS06420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DMT42_RS06440	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DMT42_RS06455	COG0124	histidyl-tRNA synthetase
DMT42_RS06465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DMT42_RS06470	COG1196	nuclear chromosome segregation
DMT42_RS06475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DMT42_RS06485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DMT42_RS06490	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMT42_RS06495	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMT42_RS06505	COG2255	four-way junction helicase activity
DMT42_RS06510	COG0632	four-way junction helicase activity
DMT42_RS06515	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DMT42_RS06520	COG0217	transcriptional regulatory protein
DMT42_RS06525	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DMT42_RS06530	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DMT42_RS06540	COG0438	transferase activity, transferring glycosyl groups
DMT42_RS06545	COG1560	Kdo2-lipid A biosynthetic process
DMT42_RS06550	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DMT42_RS06575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DMT42_RS06590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DMT42_RS06620	COG0395	ABC-type sugar transport system, permease component
DMT42_RS06625	COG1175	transmembrane transport
DMT42_RS06670	COG0456	acetyltransferase
DMT42_RS06680	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMT42_RS06745	COG1648	precorrin-2 dehydrogenase activity
DMT42_RS06745	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DMT42_RS06765	COG1464	Belongs to the NlpA lipoprotein family
DMT42_RS06770	COG2011	ABC-type metal ion transport system permease component
DMT42_RS06775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DMT42_RS06805	COG0584	glycerophosphoryl diester phosphodiesterase
DMT42_RS06810	COG0204	Acyl-transferase
DMT42_RS06810	COG0318	PFAM AMP-dependent synthetase and ligase
DMT42_RS06815	COG0477	Major facilitator Superfamily
DMT42_RS06830	COG0165	Argininosuccinate lyase
DMT42_RS06850	COG2205	protein histidine kinase activity
DMT42_RS06855	COG0745	RESPONSE REGULATOR receiver
DMT42_RS06885	COG1438	arginine binding
DMT42_RS06890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DMT42_RS06895	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DMT42_RS06900	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DMT42_RS06905	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DMT42_RS06915	COG0463	Glycosyl transferase, family 2
DMT42_RS06960	COG0697	spore germination
DMT42_RS06970	COG1649	PFAM Uncharacterised BCR, COG1649
DMT42_RS07000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMT42_RS07000	COG0072	phenylalanine-tRNA ligase activity
DMT42_RS07005	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DMT42_RS07010	COG5002	protein histidine kinase activity
DMT42_RS07015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMT42_RS07020	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DMT42_RS07025	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DMT42_RS07030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DMT42_RS07080	COG1012	belongs to the aldehyde dehydrogenase family
DMT42_RS07085	COG0174	glutamine synthetase
DMT42_RS07090	COG2186	Transcriptional regulator
DMT42_RS07095	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DMT42_RS07125	COG0517	IMP dehydrogenase activity
DMT42_RS07125	COG4175	Glycine betaine
DMT42_RS07130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMT42_RS07140	COG0564	pseudouridine synthase activity
DMT42_RS07175	COG0805	protein transport
DMT42_RS07180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DMT42_RS07210	COG0545	Peptidyl-prolyl cis-trans isomerase
DMT42_RS07215	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DMT42_RS07225	COG1609	Transcriptional regulator
DMT42_RS07230	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DMT42_RS07235	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DMT42_RS07245	COG4122	O-methyltransferase activity
DMT42_RS07250	COG1222	aaa ATPase
DMT42_RS07275	COG0517	IMP dehydrogenase activity
DMT42_RS07275	COG1994	Peptidase M50
DMT42_RS07285	COG2197	response regulator
DMT42_RS07290	COG0747	negative chemotaxis
DMT42_RS07305	COG0646	methionine synthase
DMT42_RS07305	COG1410	methionine synthase
DMT42_RS07310	COG1414	Transcriptional regulator
DMT42_RS07315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DMT42_RS07320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DMT42_RS07325	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DMT42_RS07340	COG0640	Transcriptional regulator
DMT42_RS07345	COG2186	Transcriptional regulator
DMT42_RS07355	COG0215	cysteine-tRNA ligase activity
DMT42_RS07370	COG0588	phosphoglycerate mutase activity
DMT42_RS07375	COG0598	Magnesium transport protein CorA
DMT42_RS07385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMT42_RS07390	COG0667	Aldo Keto reductase
DMT42_RS07420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMT42_RS07430	COG3012	SEC-C Motif Domain Protein
DMT42_RS07435	COG2186	Transcriptional regulator
DMT42_RS07440	COG3265	gluconokinase activity
DMT42_RS07475	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DMT42_RS07480	COG2149	membrane
DMT42_RS07505	COG1960	acyl-CoA dehydrogenase activity
DMT42_RS07520	COG0318	PFAM AMP-dependent synthetase and ligase
DMT42_RS07530	COG3876	Protein conserved in bacteria
DMT42_RS07570	COG0789	Transcriptional regulator
DMT42_RS07590	COG1960	acyl-CoA dehydrogenase activity
DMT42_RS07600	COG0640	Transcriptional regulator
DMT42_RS07630	COG2851	Citrate transporter
DMT42_RS07635	COG0243	molybdopterin cofactor binding
DMT42_RS07645	COG1309	transcriptional regulator
DMT42_RS07655	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DMT42_RS07660	COG2188	Transcriptional regulator
DMT42_RS07695	COG5343	regulation of RNA biosynthetic process
DMT42_RS07700	COG1595	DNA-templated transcription, initiation
DMT42_RS07720	COG2815	serine threonine protein kinase
DMT42_RS07720	COG0515	serine threonine protein kinase
DMT42_RS07725	COG2755	lipolytic protein G-D-S-L family
DMT42_RS07735	COG0463	Glycosyl transferase, family 2
DMT42_RS07740	COG1216	Glycosyl transferase, family 2
DMT42_RS07745	COG1649	PFAM Uncharacterised BCR, COG1649
DMT42_RS07745	COG0726	polysaccharide deacetylase
DMT42_RS07770	COG1725	Transcriptional regulator
DMT42_RS07815	COG0587	DNA-directed DNA polymerase activity
DMT42_RS07845	COG1126	abc transporter atp-binding protein
DMT42_RS07855	COG0765	amino acid transport
DMT42_RS07870	COG1799	cell septum assembly
DMT42_RS07875	COG1960	acyl-CoA dehydrogenase activity
DMT42_RS07880	COG0477	Major facilitator Superfamily
DMT42_RS07885	COG0671	phosphoesterase, PA-phosphatase related
DMT42_RS07895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DMT42_RS07925	COG1652	LysM domain
DMT42_RS07940	COG1160	GTP binding
DMT42_RS07950	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DMT42_RS07975	COG1187	pseudouridine synthase activity
DMT42_RS07980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DMT42_RS07985	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DMT42_RS08000	COG0686	Belongs to the AlaDH PNT family
DMT42_RS08010	COG0494	nUDIX hydrolase
DMT42_RS08015	COG0504	CTP synthase activity
DMT42_RS08020	COG3387	PFAM Glycoside hydrolase 15-related
DMT42_RS08030	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DMT42_RS08045	COG0438	transferase activity, transferring glycosyl groups
DMT42_RS08055	COG0497	DNA recombination
DMT42_RS08060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DMT42_RS08080	COG1120	ATPase activity
DMT42_RS08085	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMT42_RS08090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMT42_RS08095	COG0647	UMP catabolic process
DMT42_RS08130	COG2094	Belongs to the DNA glycosylase MPG family
DMT42_RS08140	COG1881	PFAM PEBP family protein
DMT42_RS08160	COG1119	ATPase activity
DMT42_RS08180	COG2197	response regulator
DMT42_RS08190	COG4221	oxidoreductase activity
DMT42_RS08195	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DMT42_RS08205	COG0842	Transport permease protein
DMT42_RS08205	COG1131	(ABC) transporter
DMT42_RS08205	COG1716	ATPase activity
DMT42_RS08215	COG0560	Phosphoserine phosphatase
DMT42_RS08215	COG3830	Belongs to the UPF0237 family
DMT42_RS08220	COG0588	phosphoglycerate mutase activity
DMT42_RS08240	COG2186	Transcriptional regulator
DMT42_RS08260	COG0312	modulator of DNA gyrase
DMT42_RS08270	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DMT42_RS08290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DMT42_RS08295	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMT42_RS08315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DMT42_RS08325	COG1063	alcohol dehydrogenase
DMT42_RS08335	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DMT42_RS08350	COG3387	PFAM Glycoside hydrolase 15-related
DMT42_RS08395	COG1024	Enoyl-CoA hydratase
DMT42_RS08405	COG0488	(ABC) transporter
DMT42_RS08435	COG0235	Class ii aldolase
DMT42_RS08450	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DMT42_RS08455	COG1492	cobalamin metabolic process
DMT42_RS08475	COG1797	cobyrinic acid a,c-diamide synthase activity
DMT42_RS08510	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
DMT42_RS08540	COG0765	amino acid transport
DMT42_RS08550	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DMT42_RS08555	COG0456	acetyltransferase
DMT42_RS08560	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DMT42_RS08565	COG1917	Cupin 2, conserved barrel domain protein
DMT42_RS08570	COG5285	phytanoyl-CoA dioxygenase
DMT42_RS08575	COG3844	kynureninase activity
DMT42_RS08600	COG1414	Transcriptional regulator
DMT42_RS08610	COG4585	Histidine kinase
DMT42_RS08620	COG0768	penicillin binding
DMT42_RS08625	COG2252	PERMEase
DMT42_RS08630	COG1595	DNA-templated transcription, initiation
DMT42_RS08670	COG4677	pectinesterase activity
DMT42_RS08680	COG3866	Pectate lyase
DMT42_RS08685	COG2755	lipolytic protein G-D-S-L family
DMT42_RS08715	COG0395	ABC-type sugar transport system, permease component
DMT42_RS08720	COG1175	transmembrane transport
DMT42_RS08730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMT42_RS08735	COG1802	Transcriptional regulator
DMT42_RS08765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMT42_RS08770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMT42_RS08775	COG1349	DNA-binding transcription factor activity
DMT42_RS08790	COG0395	ABC-type sugar transport system, permease component
DMT42_RS08795	COG1063	alcohol dehydrogenase
DMT42_RS08805	COG1309	transcriptional regulator
DMT42_RS08810	COG3547	Transposase (IS116 IS110 IS902 family)
DMT42_RS08860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMT42_RS08865	COG2171	N-acyltransferase activity
DMT42_RS08880	COG2076	Multidrug Resistance protein
DMT42_RS08885	COG2151	metal-sulfur cluster biosynthetic enzyme
DMT42_RS08890	COG0822	iron-sulfur transferase activity
DMT42_RS08895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DMT42_RS08900	COG0396	ATPase activity
DMT42_RS08910	COG0719	Fe-S assembly protein
DMT42_RS08950	COG0109	protoheme IX farnesyltransferase activity
DMT42_RS08965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DMT42_RS08980	COG0363	glucosamine-6-phosphate deaminase activity
DMT42_RS08985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMT42_RS08995	COG0395	ABC-type sugar transport system, permease component
DMT42_RS09000	COG1175	transmembrane transport
DMT42_RS09010	COG0366	Alpha amylase catalytic
DMT42_RS09020	COG1695	Transcriptional regulator
DMT42_RS09025	COG1136	(ABC) transporter
DMT42_RS09040	COG0166	Belongs to the GPI family
DMT42_RS09050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DMT42_RS09055	COG0149	triose-phosphate isomerase activity
DMT42_RS09065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DMT42_RS09075	COG1481	regulation of sporulation
DMT42_RS09080	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DMT42_RS09085	COG1660	Displays ATPase and GTPase activities
DMT42_RS09090	COG0322	excinuclease ABC activity
DMT42_RS09100	COG0723	plastoquinol--plastocyanin reductase activity
DMT42_RS09105	COG1609	Transcriptional regulator
DMT42_RS09125	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMT42_RS09135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMT42_RS09140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMT42_RS09145	COG0765	amino acid transport
DMT42_RS09150	COG1126	abc transporter atp-binding protein
DMT42_RS09155	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DMT42_RS09160	COG1619	proteins homologs of microcin C7 resistance protein MccF
DMT42_RS09165	COG0477	Major facilitator Superfamily
DMT42_RS09170	COG0387	Pfam Sodium calcium exchanger
DMT42_RS09190	COG0556	nucleotide-excision repair
DMT42_RS09200	COG0584	glycerophosphoryl diester phosphodiesterase
DMT42_RS09210	COG2313	pseudouridylate synthase activity
DMT42_RS09215	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMT42_RS09215	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DMT42_RS09220	COG2226	methyltransferase
DMT42_RS09225	COG0598	Magnesium transport protein CorA
DMT42_RS09255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DMT42_RS09260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMT42_RS09290	COG0402	S-adenosylhomocysteine deaminase activity
DMT42_RS09335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DMT42_RS09355	COG0237	dephospho-CoA kinase activity
DMT42_RS09365	COG0539	negative regulation of cytoplasmic translation
DMT42_RS09370	COG1073	alpha beta
DMT42_RS09370	COG2226	methyltransferase
DMT42_RS09375	COG1643	Atp-dependent helicase
DMT42_RS09410	COG2050	protein possibly involved in aromatic compounds catabolism
DMT42_RS09500	COG0737	Belongs to the 5'-nucleotidase family
DMT42_RS09565	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DMT42_RS10035	COG0287	Prephenate dehydrogenase
DMT42_RS10035	COG1605	Chorismate mutase
DMT42_RS10045	COG5492	domain, Protein
DMT42_RS10050	COG1349	DNA-binding transcription factor activity
DMT42_RS10070	COG0395	ABC-type sugar transport system, permease component
DMT42_RS10075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMT42_RS10080	COG0477	Major facilitator Superfamily
DMT42_RS10085	COG1846	Transcriptional regulator
DMT42_RS10090	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DMT42_RS10095	COG2304	oxidoreductase activity
DMT42_RS10115	COG0070	glutamate synthase
DMT42_RS10115	COG0069	glutamate synthase activity
DMT42_RS10115	COG0067	glutamate synthase
DMT42_RS10145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMT42_RS10150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DMT42_RS10160	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DMT42_RS10170	COG0159	tryptophan synthase activity
DMT42_RS10175	COG0133	tryptophan synthase activity
DMT42_RS10185	COG0134	indole-3-glycerol-phosphate synthase activity
DMT42_RS10205	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMT42_RS10210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DMT42_RS10220	COG0107	imidazoleglycerol-phosphate synthase activity
DMT42_RS10225	COG0251	oxidation-reduction process
DMT42_RS10230	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DMT42_RS10235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DMT42_RS10240	COG0131	Imidazoleglycerol-phosphate dehydratase
DMT42_RS10245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMT42_RS10250	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DMT42_RS10290	COG1432	Conserved Protein
DMT42_RS10295	COG0587	DNA-directed DNA polymerase activity
DMT42_RS10355	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DMT42_RS10370	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DMT42_RS10375	COG3599	regulation of cell shape
DMT42_RS10385	COG1799	cell septum assembly
DMT42_RS10395	COG1496	oxidoreductase activity
DMT42_RS10400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DMT42_RS10405	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DMT42_RS10410	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DMT42_RS10420	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DMT42_RS10425	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DMT42_RS10435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DMT42_RS10440	COG0768	penicillin binding
DMT42_RS10450	COG0275	rRNA processing
DMT42_RS10460	COG0714	Associated with various cellular activities
DMT42_RS10480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DMT42_RS10500	COG1309	transcriptional regulator
DMT42_RS10520	COG0352	thiamine-phosphate diphosphorylase activity
DMT42_RS10540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DMT42_RS10540	COG2022	thiamine diphosphate biosynthetic process
DMT42_RS10550	COG2022	thiamine diphosphate biosynthetic process
DMT42_RS10555	COG0515	serine threonine protein kinase
DMT42_RS10555	COG2815	serine threonine protein kinase
DMT42_RS10560	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DMT42_RS10570	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DMT42_RS10575	COG2193	ferroxidase activity
DMT42_RS10580	COG0243	molybdopterin cofactor binding
DMT42_RS10585	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DMT42_RS10605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMT42_RS10610	COG0205	6-phosphofructokinase activity
DMT42_RS10615	COG2197	response regulator
DMT42_RS10645	COG1940	carbohydrate kinase activity
DMT42_RS10655	COG0003	Pfam Anion-transporting ATPase
DMT42_RS10675	COG0438	transferase activity, transferring glycosyl groups
DMT42_RS10685	COG0534	Mate efflux family protein
DMT42_RS10690	COG1695	Transcriptional regulator
DMT42_RS10695	COG1472	Belongs to the glycosyl hydrolase 3 family
DMT42_RS10705	COG1175	transmembrane transport
DMT42_RS10715	COG1609	Transcriptional regulator
DMT42_RS10730	COG3883	PFAM NLP P60 protein
DMT42_RS10730	COG0791	NLP P60 protein
DMT42_RS10760	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMT42_RS10760	COG0515	serine threonine protein kinase
DMT42_RS10765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DMT42_RS10770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DMT42_RS10775	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DMT42_RS10780	COG0723	plastoquinol--plastocyanin reductase activity
DMT42_RS10785	COG2010	Cytochrome c
DMT42_RS10790	COG1845	cytochrome c oxidase, subunit III
DMT42_RS10800	COG1376	ErfK ybiS ycfS ynhG family protein
DMT42_RS10810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DMT42_RS10815	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DMT42_RS10825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMT42_RS10850	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DMT42_RS10855	COG0515	serine threonine protein kinase
DMT42_RS10855	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMT42_RS10860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMT42_RS10865	COG2197	response regulator
DMT42_RS10870	COG4585	Histidine kinase
DMT42_RS10890	COG2226	methyltransferase
DMT42_RS10895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMT42_RS10915	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DMT42_RS10935	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DMT42_RS10960	COG0438	transferase activity, transferring glycosyl groups
DMT42_RS10970	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DMT42_RS10975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMT42_RS10980	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMT42_RS10995	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DMT42_RS11025	COG1090	epimerase
DMT42_RS11040	COG0321	lipoyl(octanoyl) transferase activity
DMT42_RS11045	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DMT42_RS11065	COG0174	glutamine synthetase
DMT42_RS11070	COG0582	viral genome integration into host DNA
DMT42_RS11190	COG0501	Belongs to the peptidase M48B family
DMT42_RS11240	COG0745	RESPONSE REGULATOR receiver
DMT42_RS11255	COG2197	response regulator
DMT42_RS11290	COG1309	transcriptional regulator
DMT42_RS11325	COG0366	Alpha amylase catalytic
DMT42_RS11330	COG3833	ABC-type maltose transport systems, permease component
DMT42_RS11335	COG1175	transmembrane transport
DMT42_RS11340	COG2182	Extracellular solute-binding protein
DMT42_RS11345	COG1609	Transcriptional regulator
DMT42_RS11355	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DMT42_RS11365	COG1802	Transcriptional regulator
DMT42_RS11370	COG3938	Belongs to the proline racemase family
DMT42_RS11375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMT42_RS11385	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMT42_RS11385	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DMT42_RS11400	COG0006	proline dipeptidase activity
DMT42_RS11415	COG3511	phospholipase C
DMT42_RS11450	COG0174	glutamine synthetase
DMT42_RS11460	COG1959	2 iron, 2 sulfur cluster binding
DMT42_RS11475	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DMT42_RS11475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DMT42_RS11490	COG2814	Major facilitator Superfamily
DMT42_RS11505	COG0477	Major facilitator Superfamily
DMT42_RS11510	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DMT42_RS11555	COG1994	Peptidase M50
DMT42_RS11590	COG5398	heme oxygenase
DMT42_RS11595	COG0384	phenazine biosynthesis protein PhzF
DMT42_RS11605	COG2837	iron assimilation
DMT42_RS11640	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DMT42_RS11645	COG2814	Major facilitator Superfamily
DMT42_RS11655	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS11665	COG2259	Doxx family
DMT42_RS11675	COG2072	flavoprotein involved in K transport
DMT42_RS11720	COG0646	methionine synthase
DMT42_RS11720	COG1410	methionine synthase
DMT42_RS11725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMT42_RS11730	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DMT42_RS11745	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMT42_RS11750	COG1846	Transcriptional regulator
DMT42_RS11775	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS11785	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS11800	COG2345	Transcriptional regulator
DMT42_RS11810	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS11815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DMT42_RS11845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMT42_RS11860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DMT42_RS11870	COG2814	Major facilitator Superfamily
DMT42_RS11880	COG4770	biotin carboxylase activity
DMT42_RS11885	COG0667	Aldo Keto reductase
DMT42_RS11890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMT42_RS11900	COG0745	RESPONSE REGULATOR receiver
DMT42_RS11940	COG3022	response to hydroperoxide
DMT42_RS11945	COG0800	Aldolase
DMT42_RS11960	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DMT42_RS11970	COG2030	dehydratase
DMT42_RS11975	COG4585	Histidine kinase
DMT42_RS11980	COG3467	pyridoxamine 5'-phosphate
DMT42_RS11985	COG2197	response regulator
DMT42_RS12005	COG0477	Major facilitator Superfamily
DMT42_RS12020	COG0860	N-Acetylmuramoyl-L-alanine amidase
DMT42_RS12045	COG0438	transferase activity, transferring glycosyl groups
DMT42_RS12050	COG1309	transcriptional regulator
DMT42_RS12070	COG1657	PFAM Prenyltransferase squalene oxidase
DMT42_RS12085	COG3845	ABC transporter
DMT42_RS12120	COG4122	O-methyltransferase activity
DMT42_RS12195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DMT42_RS12250	COG1358	cellular component organization or biogenesis
DMT42_RS12295	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DMT42_RS12300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DMT42_RS12310	COG0477	Major facilitator Superfamily
DMT42_RS12315	COG1309	transcriptional regulator
DMT42_RS12330	COG0667	Aldo Keto reductase
DMT42_RS12335	COG0789	Transcriptional regulator
DMT42_RS12365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DMT42_RS12370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMT42_RS12375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMT42_RS12415	COG0583	DNA-binding transcription factor activity
DMT42_RS12435	COG2130	NADP-dependent
DMT42_RS12440	COG1764	response to oxidative stress
DMT42_RS12450	COG0251	oxidation-reduction process
DMT42_RS12490	COG4214	carbohydrate transport
DMT42_RS12500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMT42_RS12510	COG3507	Belongs to the glycosyl hydrolase 43 family
DMT42_RS12535	COG3507	Belongs to the glycosyl hydrolase 43 family
DMT42_RS12540	COG0395	ABC-type sugar transport system, permease component
DMT42_RS12580	COG3386	PFAM SMP-30 Gluconolaconase
DMT42_RS12585	COG1414	Transcriptional regulator
DMT42_RS12615	COG0318	PFAM AMP-dependent synthetase and ligase
DMT42_RS12620	COG0825	malonyl-CoA metabolic process
DMT42_RS12620	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DMT42_RS12625	COG1404	Belongs to the peptidase S8 family
DMT42_RS12650	COG1077	Cell shape determining protein MreB Mrl
DMT42_RS12690	COG1070	Carbohydrate kinase
DMT42_RS12705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMT42_RS12710	COG0358	DNA primase activity
DMT42_RS12720	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DMT42_RS12730	COG2949	membrane
DMT42_RS12735	COG0243	molybdopterin cofactor binding
DMT42_RS12765	COG1733	regulation of RNA biosynthetic process
DMT42_RS12775	COG2197	response regulator
DMT42_RS12790	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMT42_RS12795	COG2146	nitrite reductase [NAD(P)H] activity
DMT42_RS12795	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMT42_RS12815	COG1136	(ABC) transporter
DMT42_RS12825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMT42_RS12825	COG0574	Belongs to the PEP-utilizing enzyme family
DMT42_RS12830	COG1846	Transcriptional regulator
DMT42_RS12830	COG1940	carbohydrate kinase activity
DMT42_RS12835	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
DMT42_RS12865	COG0477	Major facilitator Superfamily
DMT42_RS12875	COG0667	Aldo Keto reductase
DMT42_RS12890	COG0423	glycine-tRNA ligase activity
DMT42_RS12895	COG3443	Belongs to the bacterial solute-binding protein 9 family
DMT42_RS12895	COG0803	Belongs to the bacterial solute-binding protein 9 family
DMT42_RS12900	COG1121	(ABC) transporter
DMT42_RS12905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DMT42_RS12920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DMT42_RS12925	COG1381	Involved in DNA repair and RecF pathway recombination
DMT42_RS12940	COG1595	DNA-templated transcription, initiation
DMT42_RS12960	COG2197	response regulator
DMT42_RS12965	COG4585	Histidine kinase
DMT42_RS12970	COG2409	Drug exporters of the RND superfamily
DMT42_RS12980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMT42_RS13020	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DMT42_RS13030	COG2315	Protein conserved in bacteria
DMT42_RS13050	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DMT42_RS13060	COG4948	Mandelate Racemase Muconate Lactonizing
DMT42_RS13065	COG1414	Transcriptional regulator
DMT42_RS13080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DMT42_RS13085	COG1234	tRNA 3'-trailer cleavage
DMT42_RS13090	COG0537	adenosine 5'-monophosphoramidase activity
DMT42_RS13095	COG0793	Belongs to the peptidase S41A family
DMT42_RS13095	COG4946	Tricorn protease homolog
DMT42_RS13120	COG2070	2-Nitropropane dioxygenase
DMT42_RS13125	COG0484	heat shock protein binding
DMT42_RS13130	COG1420	regulation of RNA biosynthetic process
DMT42_RS13160	COG0481	GTPase activity
DMT42_RS13165	COG0268	Binds directly to 16S ribosomal RNA
DMT42_RS13305	COG1596	polysaccharide export
DMT42_RS13305	COG1555	photosystem II stabilization
DMT42_RS13310	COG1307	EDD domain protein, DegV family
DMT42_RS13320	COG0495	leucyl-tRNA aminoacylation
DMT42_RS13335	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DMT42_RS13355	COG0477	Major facilitator Superfamily
DMT42_RS13370	COG0588	phosphoglycerate mutase activity
DMT42_RS13375	COG0799	negative regulation of ribosome biogenesis
DMT42_RS13385	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DMT42_RS13400	COG0501	Belongs to the peptidase M48B family
DMT42_RS13415	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DMT42_RS13425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DMT42_RS13435	COG1216	Glycosyl transferase, family 2
DMT42_RS13440	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DMT42_RS13440	COG0463	Glycosyl transferase, family 2
DMT42_RS13445	COG0438	transferase activity, transferring glycosyl groups
DMT42_RS13450	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DMT42_RS13455	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DMT42_RS13460	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DMT42_RS13465	COG1530	ribonuclease E activity
DMT42_RS13485	COG2814	Major facilitator Superfamily
DMT42_RS13505	COG0772	Belongs to the SEDS family
DMT42_RS13510	COG0768	penicillin binding
DMT42_RS13525	COG1077	Cell shape determining protein MreB Mrl
DMT42_RS13530	COG0105	UTP biosynthetic process
DMT42_RS13540	COG0285	dihydrofolate synthase activity
DMT42_RS13545	COG0525	valine-tRNA ligase activity
DMT42_RS13555	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DMT42_RS13560	COG0740	serine-type endopeptidase activity
DMT42_RS13565	COG0740	serine-type endopeptidase activity
DMT42_RS13570	COG0544	peptidyl-prolyl cis-trans isomerase activity
DMT42_RS13600	COG4552	Acetyltransferase involved in intracellular survival and related
DMT42_RS13615	COG1113	amino acid transport
DMT42_RS13620	COG0515	serine threonine protein kinase
DMT42_RS13630	COG1268	BioY protein
DMT42_RS13645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMT42_RS13650	COG1116	anion transmembrane transporter activity
DMT42_RS13655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMT42_RS13670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DMT42_RS13685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DMT42_RS13755	COG2814	Major facilitator Superfamily
DMT42_RS13760	COG0583	DNA-binding transcription factor activity
DMT42_RS13775	COG0583	DNA-binding transcription factor activity
DMT42_RS13785	COG0697	spore germination
DMT42_RS13795	COG1846	Transcriptional regulator
DMT42_RS13805	COG1595	DNA-templated transcription, initiation
DMT42_RS13810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DMT42_RS13815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DMT42_RS13845	COG1136	(ABC) transporter
DMT42_RS13860	COG0668	transmembrane transport
DMT42_RS13865	COG1940	carbohydrate kinase activity
DMT42_RS13875	COG1175	transmembrane transport
DMT42_RS13880	COG0395	ABC-type sugar transport system, permease component
DMT42_RS13885	COG1486	melibiose metabolic process
DMT42_RS13900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMT42_RS13930	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DMT42_RS13950	COG1136	(ABC) transporter
DMT42_RS13980	COG0629	single-stranded DNA binding
DMT42_RS13985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DMT42_RS14015	COG1278	Cold shock
DMT42_RS14035	COG4585	Histidine kinase
DMT42_RS14040	COG2197	response regulator
DMT42_RS14050	COG0674	pyruvate-flavodoxin oxidoreductase activity
DMT42_RS14050	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DMT42_RS14055	COG1013	pyruvate-flavodoxin oxidoreductase activity
DMT42_RS14100	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMT42_RS14115	COG3321	synthase
DMT42_RS14115	COG0604	alcohol dehydrogenase
DMT42_RS14135	COG0318	PFAM AMP-dependent synthetase and ligase
DMT42_RS14200	COG3629	intracellular signal transduction
DMT42_RS14215	COG2304	oxidoreductase activity
DMT42_RS14255	COG0438	transferase activity, transferring glycosyl groups
DMT42_RS14270	COG0728	peptidoglycan biosynthetic process
DMT42_RS14320	COG2304	oxidoreductase activity
DMT42_RS14360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMT42_RS14370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DMT42_RS14390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DMT42_RS14410	COG1609	Transcriptional regulator
DMT42_RS14415	COG1129	ABC transporter
DMT42_RS14420	COG1879	ABC-type sugar transport system periplasmic component
DMT42_RS14425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMT42_RS14430	COG1869	D-ribose catabolic process
DMT42_RS14445	COG0673	inositol 2-dehydrogenase activity
DMT42_RS14505	COG1472	Belongs to the glycosyl hydrolase 3 family
DMT42_RS14540	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMT42_RS14540	COG0515	serine threonine protein kinase
DMT42_RS14550	COG1280	lysine exporter protein (LysE YggA)
DMT42_RS14560	COG0028	Belongs to the TPP enzyme family
DMT42_RS14570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMT42_RS14585	COG0702	epimerase
DMT42_RS14590	COG1073	alpha beta
DMT42_RS14610	COG1946	Acyl-CoA thioesterase
DMT42_RS14625	COG1309	transcriptional regulator
DMT42_RS14630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DMT42_RS14645	COG1960	acyl-CoA dehydrogenase activity
DMT42_RS14665	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DMT42_RS14700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DMT42_RS14710	COG0589	response to stress
DMT42_RS14720	COG4977	sequence-specific DNA binding
DMT42_RS14725	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DMT42_RS14740	COG1073	alpha beta
DMT42_RS14740	COG2226	methyltransferase
DMT42_RS14810	COG3979	chitinase
DMT42_RS14820	COG0745	RESPONSE REGULATOR receiver
DMT42_RS14845	COG0406	alpha-ribazole phosphatase activity
DMT42_RS14895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMT42_RS14915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMT42_RS14920	COG0765	amino acid transport
DMT42_RS14925	COG0765	amino acid transport
DMT42_RS14930	COG1126	abc transporter atp-binding protein
DMT42_RS14950	COG3397	chitin binding
DMT42_RS15005	COG1940	carbohydrate kinase activity
DMT42_RS15010	COG0673	inositol 2-dehydrogenase activity
DMT42_RS15015	COG4702	Belongs to the UPF0303 family
DMT42_RS15030	COG0706	membrane insertase activity
DMT42_RS15090	COG0596	Alpha beta hydrolase
DMT42_RS15100	COG0071	Belongs to the small heat shock protein (HSP20) family
DMT42_RS15125	COG2733	membrane
DMT42_RS15140	COG4555	ABC transporter
DMT42_RS15155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DMT42_RS15190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DMT42_RS15200	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DMT42_RS15205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DMT42_RS15210	COG1263	PTS System
DMT42_RS15215	COG1263	PTS System
DMT42_RS15220	COG1234	tRNA 3'-trailer cleavage
DMT42_RS15245	COG1113	amino acid transport
DMT42_RS15260	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DMT42_RS15270	COG1335	isochorismatase
DMT42_RS15305	COG0277	FAD linked oxidase domain protein
DMT42_RS15315	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DMT42_RS15335	COG1174	glycine betaine transport
DMT42_RS15340	COG1732	Glycine betaine
DMT42_RS15355	COG3480	Lon protease (S16) C-terminal proteolytic domain
DMT42_RS15360	COG4948	Mandelate Racemase Muconate Lactonizing
DMT42_RS15375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMT42_RS15420	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DMT42_RS15435	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMT42_RS15445	COG1678	Uncharacterized ACR, COG1678
DMT42_RS15450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DMT42_RS15455	COG0776	regulation of translation
DMT42_RS15465	COG3973	AAA domain
DMT42_RS15490	COG2223	nitrite transmembrane transporter activity
DMT42_RS15515	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DMT42_RS15560	COG0778	Nitroreductase
DMT42_RS15580	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DMT42_RS15585	COG0793	Belongs to the peptidase S41A family
DMT42_RS15595	COG2884	Cell division ATP-binding protein ftsE
DMT42_RS15610	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DMT42_RS15615	COG0515	serine threonine protein kinase
DMT42_RS15620	COG0515	serine threonine protein kinase
DMT42_RS15635	COG1175	transmembrane transport
DMT42_RS15640	COG0395	ABC-type sugar transport system, permease component
DMT42_RS15645	COG1216	Glycosyl transferase, family 2
DMT42_RS15655	COG1764	response to oxidative stress
DMT42_RS15660	COG1846	Transcriptional regulator
DMT42_RS15690	COG1388	LysM domain
DMT42_RS15690	COG1134	teichoic acid transport
DMT42_RS15695	COG2902	Dehydrogenase
DMT42_RS15720	COG0653	protein targeting
DMT42_RS15730	COG3214	Protein conserved in bacteria
DMT42_RS15735	COG2197	response regulator
DMT42_RS15740	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DMT42_RS15750	COG0823	Involved in the tonB-independent uptake of proteins
DMT42_RS15755	COG5000	phosphorelay sensor kinase activity
DMT42_RS15755	COG5002	protein histidine kinase activity
DMT42_RS15760	COG0745	RESPONSE REGULATOR receiver
DMT42_RS15765	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DMT42_RS15785	COG0714	Associated with various cellular activities
DMT42_RS15830	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DMT42_RS15850	COG1482	cell wall glycoprotein biosynthetic process
DMT42_RS15860	COG2835	tetraacyldisaccharide 4'-kinase activity
DMT42_RS15865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMT42_RS15905	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DMT42_RS15910	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
DMT42_RS15910	COG0778	Nitroreductase
DMT42_RS15935	COG1316	TRANSCRIPTIONal
DMT42_RS15940	COG1316	TRANSCRIPTIONal
DMT42_RS15945	COG1316	TRANSCRIPTIONal
DMT42_RS15950	COG0463	Glycosyl transferase, family 2
DMT42_RS15955	COG1316	TRANSCRIPTIONal
DMT42_RS15970	COG2226	methyltransferase
DMT42_RS15980	COG1316	TRANSCRIPTIONal
DMT42_RS15985	COG1607	acyl-coa hydrolase
DMT42_RS15990	COG3795	YCII-related domain
DMT42_RS15995	COG4941	Belongs to the sigma-70 factor family
DMT42_RS16005	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DMT42_RS16030	COG0789	Transcriptional regulator
DMT42_RS16055	COG2205	protein histidine kinase activity
DMT42_RS16060	COG0745	RESPONSE REGULATOR receiver
DMT42_RS16065	COG3104	oligopeptide transport
DMT42_RS16080	COG1191	sigma factor activity
DMT42_RS16095	COG1228	amidohydrolase
DMT42_RS16105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMT42_RS16110	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DMT42_RS16155	COG4221	oxidoreductase activity
DMT42_RS16170	COG2755	lipolytic protein G-D-S-L family
DMT42_RS16175	COG0183	Belongs to the thiolase family
DMT42_RS16210	COG1136	(ABC) transporter
DMT42_RS16215	COG0577	efflux transmembrane transporter activity
DMT42_RS16220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DMT42_RS16245	COG1252	NADH dehydrogenase
DMT42_RS16250	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
DMT42_RS16270	COG0148	phosphopyruvate hydratase activity
DMT42_RS16405	COG0789	Transcriptional regulator
DMT42_RS16415	COG0577	efflux transmembrane transporter activity
DMT42_RS16420	COG1136	(ABC) transporter
DMT42_RS16425	COG0477	Major facilitator Superfamily
DMT42_RS16435	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMT42_RS16465	COG4585	Histidine kinase
DMT42_RS16480	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DMT42_RS16485	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DMT42_RS16490	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DMT42_RS16495	COG0193	aminoacyl-tRNA hydrolase activity
DMT42_RS16510	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DMT42_RS16520	COG1309	transcriptional regulator
DMT42_RS16535	COG4106	trans-aconitate 2-methyltransferase activity
DMT42_RS16545	COG2197	response regulator
DMT42_RS16555	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DMT42_RS16595	COG0488	(ABC) transporter
DMT42_RS16605	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DMT42_RS16610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DMT42_RS16615	COG3583	domain protein
DMT42_RS16615	COG3584	3D domain protein
DMT42_RS16620	COG0084	hydrolase, TatD family'
DMT42_RS16660	COG0310	cobalt ion transport
DMT42_RS16670	COG1122	ATPase activity
DMT42_RS16675	COG1846	Transcriptional regulator
DMT42_RS16680	COG1764	response to oxidative stress
DMT42_RS16705	COG0442	prolyl-tRNA aminoacylation
DMT42_RS16725	COG2409	Drug exporters of the RND superfamily
DMT42_RS16735	COG4946	Tricorn protease homolog
DMT42_RS16735	COG0793	Belongs to the peptidase S41A family
DMT42_RS16750	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS16755	COG2267	carboxylic ester hydrolase activity
DMT42_RS16760	COG2072	flavoprotein involved in K transport
DMT42_RS16770	COG0708	Exodeoxyribonuclease III
DMT42_RS16780	COG2197	response regulator
DMT42_RS16790	COG1136	(ABC) transporter
DMT42_RS16795	COG0577	efflux transmembrane transporter activity
DMT42_RS16800	COG2814	Major facilitator Superfamily
DMT42_RS16810	COG0583	DNA-binding transcription factor activity
DMT42_RS16825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DMT42_RS16830	COG0315	cyclic pyranopterin monophosphate synthase activity
DMT42_RS16830	COG0521	Mo-molybdopterin cofactor biosynthetic process
DMT42_RS16835	COG0315	cyclic pyranopterin monophosphate synthase activity
DMT42_RS16845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DMT42_RS16850	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DMT42_RS16880	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DMT42_RS16890	COG1970	mechanosensitive ion channel activity
DMT42_RS16900	COG3191	aminopeptidase activity
DMT42_RS16920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DMT42_RS16920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DMT42_RS16920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DMT42_RS16925	COG1105	Belongs to the carbohydrate kinase PfkB family
DMT42_RS16930	COG1349	DNA-binding transcription factor activity
DMT42_RS16935	COG0477	Major facilitator Superfamily
DMT42_RS16960	COG1247	-acetyltransferase
DMT42_RS16965	COG3384	dioxygenase
DMT42_RS16970	COG1846	Transcriptional regulator
DMT42_RS17060	COG0386	Belongs to the glutathione peroxidase family
DMT42_RS17115	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DMT42_RS17160	COG3629	intracellular signal transduction
DMT42_RS17160	COG3903	Transcriptional regulator
DMT42_RS17185	COG0515	serine threonine protein kinase
DMT42_RS17185	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMT42_RS17200	COG1522	sequence-specific DNA binding
DMT42_RS17205	COG1280	lysine exporter protein (LysE YggA)
DMT42_RS17215	COG0259	pyridoxamine-phosphate oxidase activity
DMT42_RS17230	COG2072	flavoprotein involved in K transport
DMT42_RS17255	COG1595	DNA-templated transcription, initiation
DMT42_RS17305	COG0596	Alpha beta hydrolase
DMT42_RS17315	COG4821	SIS domain
DMT42_RS17335	COG0259	pyridoxamine-phosphate oxidase activity
DMT42_RS17340	COG1309	transcriptional regulator
DMT42_RS17350	COG0318	PFAM AMP-dependent synthetase and ligase
DMT42_RS17365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DMT42_RS17390	COG5006	permease, DMT superfamily
DMT42_RS17395	COG0277	FAD linked oxidase domain protein
DMT42_RS17395	COG0247	lactate metabolic process
DMT42_RS17400	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DMT42_RS17410	COG1733	regulation of RNA biosynthetic process
DMT42_RS17415	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DMT42_RS17455	COG0667	Aldo Keto reductase
DMT42_RS17485	COG2252	PERMEase
DMT42_RS17495	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DMT42_RS17510	COG2814	Major facilitator Superfamily
DMT42_RS17520	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DMT42_RS17525	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DMT42_RS17530	COG1278	Cold shock
DMT42_RS17560	COG1061	Type III restriction enzyme res subunit
DMT42_RS17575	COG3973	AAA domain
DMT42_RS17615	COG1737	Transcriptional regulator
DMT42_RS17620	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DMT42_RS17625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DMT42_RS17660	COG0459	protein refolding
DMT42_RS17665	COG1278	Cold shock
DMT42_RS17680	COG0463	Glycosyl transferase, family 2
DMT42_RS17685	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DMT42_RS17795	COG0723	plastoquinol--plastocyanin reductase activity
DMT42_RS17795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DMT42_RS17815	COG3842	ATPase activity
DMT42_RS17825	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DMT42_RS17840	COG0215	cysteine-tRNA ligase activity
DMT42_RS17845	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DMT42_RS17850	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DMT42_RS17860	COG1329	Transcriptional regulator
DMT42_RS17880	COG5002	protein histidine kinase activity
DMT42_RS17910	COG0318	PFAM AMP-dependent synthetase and ligase
DMT42_RS17915	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS17940	COG0667	Aldo Keto reductase
DMT42_RS17990	COG0588	phosphoglycerate mutase activity
DMT42_RS18030	COG0438	transferase activity, transferring glycosyl groups
DMT42_RS18100	COG2186	Transcriptional regulator
DMT42_RS18110	COG2188	Transcriptional regulator
DMT42_RS18115	COG4552	Acetyltransferase involved in intracellular survival and related
DMT42_RS18125	COG1490	D-aminoacyl-tRNA deacylase activity
DMT42_RS18130	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DMT42_RS18135	COG0735	belongs to the Fur family
DMT42_RS18140	COG3485	protocatechuate 3,4-dioxygenase
DMT42_RS18180	COG2897	thiosulfate sulfurtransferase activity
DMT42_RS18210	COG0745	RESPONSE REGULATOR receiver
DMT42_RS18215	COG1609	Transcriptional regulator
DMT42_RS18220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMT42_RS18230	COG0745	RESPONSE REGULATOR receiver
DMT42_RS18235	COG2972	Histidine kinase
DMT42_RS18235	COG2205	protein histidine kinase activity
DMT42_RS18240	COG3866	Pectate lyase
DMT42_RS18250	COG0737	Belongs to the 5'-nucleotidase family
DMT42_RS18255	COG0456	acetyltransferase
DMT42_RS18285	COG1725	Transcriptional regulator
DMT42_RS18305	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DMT42_RS18315	COG0406	alpha-ribazole phosphatase activity
DMT42_RS18315	COG0494	nUDIX hydrolase
DMT42_RS18335	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DMT42_RS18340	COG0306	phosphate transporter
DMT42_RS18350	COG1937	Protein conserved in bacteria
DMT42_RS18365	COG0277	FAD linked oxidase domain protein
DMT42_RS18370	COG0671	phosphoesterase, PA-phosphatase related
DMT42_RS18375	COG0739	heme binding
DMT42_RS18375	COG1196	nuclear chromosome segregation
DMT42_RS18375	COG0741	lytic transglycosylase activity
DMT42_RS18395	COG3209	COG3209 Rhs family protein
DMT42_RS18415	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS18460	COG1131	(ABC) transporter
DMT42_RS18470	COG4585	Histidine kinase
DMT42_RS18475	COG2197	response regulator
DMT42_RS18520	COG1252	NADH dehydrogenase
DMT42_RS18550	COG0579	oxidoreductase
DMT42_RS18555	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DMT42_RS18585	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMT42_RS18595	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMT42_RS18595	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMT42_RS18615	COG0513	Belongs to the DEAD box helicase family
DMT42_RS18660	COG1643	Atp-dependent helicase
DMT42_RS18695	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DMT42_RS18720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMT42_RS18725	COG0047	phosphoribosylformylglycinamidine synthase activity
DMT42_RS18730	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMT42_RS18765	COG2197	response regulator
DMT42_RS18775	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DMT42_RS18785	COG0501	Belongs to the peptidase M48B family
DMT42_RS18790	COG0151	Belongs to the GarS family
DMT42_RS18885	COG1247	-acetyltransferase
DMT42_RS18890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMT42_RS18895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DMT42_RS18900	COG0640	Transcriptional regulator
DMT42_RS18915	COG2197	response regulator
DMT42_RS18920	COG4585	Histidine kinase
DMT42_RS18930	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS18970	COG0433	COG0433 Predicted ATPase
DMT42_RS18985	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DMT42_RS19025	COG1191	sigma factor activity
DMT42_RS19030	COG1191	sigma factor activity
DMT42_RS19050	COG2353	YceI-like domain
DMT42_RS19055	COG3467	pyridoxamine 5'-phosphate
DMT42_RS19065	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DMT42_RS19075	COG2205	protein histidine kinase activity
DMT42_RS19080	COG0745	RESPONSE REGULATOR receiver
DMT42_RS19130	COG0784	Response regulator, receiver
DMT42_RS19135	COG1309	transcriptional regulator
DMT42_RS19140	COG2814	Major facilitator Superfamily
DMT42_RS19150	COG0318	PFAM AMP-dependent synthetase and ligase
DMT42_RS19155	COG1595	DNA-templated transcription, initiation
DMT42_RS19180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMT42_RS19220	COG0006	proline dipeptidase activity
DMT42_RS19260	COG1999	signal sequence binding
DMT42_RS19275	COG2837	iron assimilation
DMT42_RS19285	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DMT42_RS19290	COG0561	phosphatase activity
DMT42_RS19315	COG1131	(ABC) transporter
DMT42_RS19330	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DMT42_RS19345	COG0561	phosphatase activity
DMT42_RS19350	COG0739	heme binding
DMT42_RS19350	COG0741	lytic transglycosylase activity
DMT42_RS19350	COG1196	nuclear chromosome segregation
DMT42_RS19355	COG4988	ABC transporter
DMT42_RS19360	COG1294	oxidase, subunit
DMT42_RS19365	COG1271	oxidase subunit
DMT42_RS19375	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMT42_RS19380	COG1609	Transcriptional regulator
DMT42_RS19395	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DMT42_RS19410	COG1414	Transcriptional regulator
DMT42_RS19420	COG0662	Cupin 2, conserved barrel domain protein
DMT42_RS19425	COG1950	PFAM Membrane protein of
DMT42_RS19430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMT42_RS19435	COG0626	cystathionine gamma-synthase activity
DMT42_RS19470	COG0305	Participates in initiation and elongation during chromosome replication
DMT42_RS19480	COG0359	binds to the 23S rRNA
DMT42_RS19485	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DMT42_RS19490	COG0629	single-stranded DNA binding
DMT42_RS19495	COG0360	Binds together with S18 to 16S ribosomal RNA
DMT42_RS19520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DMT42_RS19545	COG0617	tRNA 3'-terminal CCA addition
DMT42_RS19560	COG2815	serine threonine protein kinase
DMT42_RS19560	COG0515	serine threonine protein kinase
DMT42_RS19565	COG1595	DNA-templated transcription, initiation
DMT42_RS19575	COG0492	ferredoxin-NADP+ reductase activity
DMT42_RS19580	COG3118	belongs to the thioredoxin family
DMT42_RS19595	COG1192	Involved in chromosome partitioning
DMT42_RS19600	COG0357	Ribosomal RNA small subunit methyltransferase G
DMT42_RS19610	COG0706	membrane insertase activity
DMT42_RS19615	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DMT42_RS19620	COG0594	ribonuclease P activity
DMT42_RS19625	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DMT42_RS19635	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DMT42_RS19645	COG0592	DNA-directed DNA polymerase activity
DMT42_RS19650	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DMT42_RS19655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DMT42_RS19660	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DMT42_RS19665	COG0187	DNA topoisomerase II activity
DMT42_RS19670	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMT42_RS19705	COG0515	serine threonine protein kinase
DMT42_RS19730	COG4566	intracellular signal transduction
DMT42_RS19765	COG0477	Major facilitator Superfamily
DMT42_RS19780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMT42_RS19805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DMT42_RS19820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DMT42_RS19855	COG0705	Rhomboid family
DMT42_RS19880	COG3764	Sortase (surface protein transpeptidase)
DMT42_RS19885	COG3764	Sortase (surface protein transpeptidase)
DMT42_RS19890	COG0515	serine threonine protein kinase
DMT42_RS19900	COG0768	penicillin binding
DMT42_RS19915	COG1716	ATPase activity
DMT42_RS19920	COG1716	ATPase activity
DMT42_RS19930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DMT42_RS19970	COG1250	3-hydroxyacyl-CoA dehydrogenase
DMT42_RS19975	COG1309	transcriptional regulator
DMT42_RS19985	COG1522	sequence-specific DNA binding
DMT42_RS20035	COG0604	alcohol dehydrogenase
DMT42_RS20035	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS20035	COG3321	synthase
DMT42_RS20050	COG0515	serine threonine protein kinase
DMT42_RS20055	COG0515	serine threonine protein kinase
DMT42_RS20060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DMT42_RS20070	COG0022	dehydrogenase e1 component
DMT42_RS20075	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMT42_RS20140	COG1362	aminopeptidase activity
DMT42_RS20145	COG1960	acyl-CoA dehydrogenase activity
DMT42_RS20160	COG1741	Belongs to the pirin family
DMT42_RS20180	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DMT42_RS20210	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMT42_RS20235	COG2267	carboxylic ester hydrolase activity
DMT42_RS20240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMT42_RS20290	COG1957	nucleoside hydrolase
DMT42_RS20295	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DMT42_RS20360	COG3540	Alkaline phosphatase
DMT42_RS20385	COG1725	Transcriptional regulator
DMT42_RS20390	COG1131	(ABC) transporter
DMT42_RS20420	COG0714	Associated with various cellular activities
DMT42_RS20445	COG1278	Cold shock
DMT42_RS20450	COG2175	clavaminate synthase activity
DMT42_RS20460	COG4521	taurine ABC transporter
DMT42_RS20465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMT42_RS20475	COG0667	Aldo Keto reductase
DMT42_RS20510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMT42_RS20515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMT42_RS20550	COG1595	DNA-templated transcription, initiation
DMT42_RS20565	COG1309	transcriptional regulator
DMT42_RS20595	COG2197	response regulator
DMT42_RS20600	COG4585	Histidine kinase
DMT42_RS20605	COG2409	Drug exporters of the RND superfamily
DMT42_RS20615	COG0513	Belongs to the DEAD box helicase family
DMT42_RS20620	COG1278	Cold shock
DMT42_RS20635	COG1191	sigma factor activity
DMT42_RS20655	COG1366	Belongs to the anti-sigma-factor antagonist family
DMT42_RS20665	COG2172	sigma factor antagonist activity
DMT42_RS20685	COG0477	Major facilitator Superfamily
DMT42_RS20710	COG0717	Belongs to the dCTP deaminase family
DMT42_RS20730	COG3386	PFAM SMP-30 Gluconolaconase
DMT42_RS20735	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DMT42_RS20750	COG2181	nitrate reductase activity
DMT42_RS20750	COG0247	lactate metabolic process
DMT42_RS20755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DMT42_RS20760	COG0443	Heat shock 70 kDa protein
DMT42_RS20765	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DMT42_RS20770	COG0484	heat shock protein binding
DMT42_RS20775	COG0789	Transcriptional regulator
DMT42_RS20795	COG4213	ABC transporter substrate-binding protein
DMT42_RS20835	COG0542	response to heat
DMT42_RS20855	COG0572	uridine kinase
DMT42_RS20875	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DMT42_RS20895	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DMT42_RS20900	COG0191	fructose-bisphosphate aldolase activity
DMT42_RS20905	COG0477	Major facilitator Superfamily
DMT42_RS20920	COG3844	kynureninase activity
DMT42_RS20940	COG4585	Histidine kinase
DMT42_RS20945	COG2197	response regulator
DMT42_RS20950	COG0736	holo-[acyl-carrier-protein] synthase activity
DMT42_RS20955	COG0563	adenylate kinase activity
DMT42_RS20965	COG0009	L-threonylcarbamoyladenylate synthase
DMT42_RS20985	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DMT42_RS21030	COG0066	3-isopropylmalate dehydratase activity
DMT42_RS21035	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DMT42_RS21050	COG2197	response regulator
DMT42_RS21055	COG4585	Histidine kinase
DMT42_RS21060	COG2197	response regulator
DMT42_RS21070	COG2124	cytochrome p450
DMT42_RS21080	COG3559	Exporter of polyketide antibiotics
DMT42_RS21085	COG1131	(ABC) transporter
DMT42_RS21100	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DMT42_RS21115	COG0577	efflux transmembrane transporter activity
DMT42_RS21115	COG1136	(ABC) transporter
DMT42_RS21120	COG4585	Histidine kinase
DMT42_RS21125	COG2197	response regulator
DMT42_RS21140	COG1802	Transcriptional regulator
DMT42_RS21145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DMT42_RS21150	COG0693	protein deglycase activity
DMT42_RS21175	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DMT42_RS21180	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DMT42_RS21205	COG0305	Participates in initiation and elongation during chromosome replication
DMT42_RS21225	COG1595	DNA-templated transcription, initiation
DMT42_RS21250	COG0701	Predicted permease
DMT42_RS21270	COG2319	Wd-40 repeat
DMT42_RS21270	COG4249	Peptidase C14 caspase catalytic subunit p20
DMT42_RS21275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMT42_RS21345	COG2255	four-way junction helicase activity
DMT42_RS21375	COG1408	metallophosphoesterase
DMT42_RS21385	COG3409	Peptidoglycan-binding domain 1 protein
DMT42_RS21405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DMT42_RS21420	COG0003	Pfam Anion-transporting ATPase
DMT42_RS21435	COG0251	oxidation-reduction process
DMT42_RS21445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMT42_RS21480	COG2267	carboxylic ester hydrolase activity
DMT42_RS21495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DMT42_RS21500	COG0659	secondary active sulfate transmembrane transporter activity
DMT42_RS21565	COG1366	Belongs to the anti-sigma-factor antagonist family
DMT42_RS21570	COG2172	sigma factor antagonist activity
DMT42_RS21575	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DMT42_RS21595	COG1754	DNA topoisomerase type I activity
DMT42_RS21595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DMT42_RS21600	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DMT42_RS21635	COG3629	intracellular signal transduction
DMT42_RS21635	COG3903	Transcriptional regulator
DMT42_RS21640	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMT42_RS21640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMT42_RS21700	COG1012	belongs to the aldehyde dehydrogenase family
DMT42_RS21705	COG2318	DinB family
DMT42_RS21715	COG0076	glutamate decarboxylase activity
DMT42_RS21720	COG0393	Putative heavy-metal-binding
DMT42_RS21725	COG0586	Pfam SNARE associated Golgi protein
DMT42_RS21735	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DMT42_RS21740	COG2027	D-alanyl-D-alanine carboxypeptidase
DMT42_RS21750	COG0037	tRNA processing
DMT42_RS21765	COG0302	gtp cyclohydrolase
DMT42_RS21785	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DMT42_RS21800	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DMT42_RS21800	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DMT42_RS21825	COG0649	NAD binding
DMT42_RS21840	COG2197	response regulator
DMT42_RS21845	COG1660	Displays ATPase and GTPase activities
DMT42_RS21870	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DMT42_RS21875	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DMT42_RS21885	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DMT42_RS21905	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DMT42_RS21940	COG0739	heme binding
DMT42_RS21955	COG2205	protein histidine kinase activity
DMT42_RS21960	COG0745	RESPONSE REGULATOR receiver
DMT42_RS21970	COG1595	DNA-templated transcription, initiation
DMT42_RS21980	COG1733	regulation of RNA biosynthetic process
DMT42_RS21995	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DMT42_RS22015	COG0248	Ppx GppA phosphatase
DMT42_RS22020	COG1082	Xylose isomerase domain protein TIM barrel
DMT42_RS22030	COG0129	dihydroxy-acid dehydratase activity
DMT42_RS22035	COG0515	serine threonine protein kinase
DMT42_RS22035	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMT42_RS22040	COG4991	sh3 domain protein
DMT42_RS22045	COG4991	sh3 domain protein
DMT42_RS22060	COG0842	Transport permease protein
DMT42_RS22060	COG1129	ABC transporter
DMT42_RS22070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DMT42_RS22085	COG0180	Tryptophanyl-tRNA synthetase
DMT42_RS22110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMT42_RS22120	COG0738	Major facilitator superfamily
DMT42_RS22125	COG0123	including yeast histone deacetylase and acetoin utilization protein
DMT42_RS22175	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DMT42_RS22180	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DMT42_RS22185	COG0181	hydroxymethylbilane synthase activity
DMT42_RS22190	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DMT42_RS22190	COG1648	precorrin-2 dehydrogenase activity
DMT42_RS22195	COG0113	porphobilinogen synthase activity
DMT42_RS22200	COG3963	phosphatidate phosphatase activity
DMT42_RS22205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMT42_RS22225	COG0018	arginyl-trna synthetase
DMT42_RS22230	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DMT42_RS22250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DMT42_RS22275	COG1690	Belongs to the RtcB family
DMT42_RS22290	COG1742	UPF0060 membrane protein
DMT42_RS22300	COG1846	Transcriptional regulator
DMT42_RS22325	COG1733	regulation of RNA biosynthetic process
DMT42_RS22330	COG0604	alcohol dehydrogenase
DMT42_RS22335	COG0477	Major facilitator Superfamily
DMT42_RS22370	COG2205	protein histidine kinase activity
DMT42_RS22390	COG0531	amino acid
DMT42_RS22410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMT42_RS22415	COG0640	Transcriptional regulator
DMT42_RS22420	COG2072	flavoprotein involved in K transport
DMT42_RS22435	COG1509	lysine 2,3-aminomutase activity
DMT42_RS22460	COG0477	Major facilitator Superfamily
DMT42_RS22470	COG0583	DNA-binding transcription factor activity
DMT42_RS22485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DMT42_RS22490	COG0406	alpha-ribazole phosphatase activity
DMT42_RS22500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DMT42_RS22505	COG0785	Cytochrome C biogenesis protein
DMT42_RS22510	COG1333	cytochrome c biogenesis protein
DMT42_RS22515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DMT42_RS22560	COG0697	spore germination
DMT42_RS22565	COG0583	DNA-binding transcription factor activity
DMT42_RS22575	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DMT42_RS22585	COG0163	prenyltransferase activity
DMT42_RS22595	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DMT42_RS22600	COG1573	uracil-dna glycosylase
DMT42_RS22615	COG1309	transcriptional regulator
DMT42_RS22625	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS22645	COG2226	methyltransferase
DMT42_RS22665	COG1278	Cold shock
DMT42_RS22670	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DMT42_RS22675	COG0515	serine threonine protein kinase
DMT42_RS22675	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMT42_RS22685	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DMT42_RS22715	COG2226	methyltransferase
DMT42_RS22730	COG0242	peptide deformylase activity
DMT42_RS22745	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMT42_RS22750	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMT42_RS22755	COG0649	NAD binding
DMT42_RS22765	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DMT42_RS22770	COG1034	ATP synthesis coupled electron transport
DMT42_RS22775	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DMT42_RS22780	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMT42_RS22785	COG0839	Belongs to the complex I subunit 6 family
DMT42_RS22790	COG0713	ATP synthesis coupled electron transport
DMT42_RS22795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DMT42_RS22805	COG1007	ATP synthesis coupled electron transport
DMT42_RS22815	COG0514	ATP-dependent DNA helicase (RecQ)
DMT42_RS22840	COG0561	phosphatase activity
DMT42_RS22850	COG0142	geranyltranstransferase activity
DMT42_RS22860	COG1131	(ABC) transporter
DMT42_RS22895	COG0702	epimerase
DMT42_RS22900	COG1733	regulation of RNA biosynthetic process
DMT42_RS22905	COG1013	pyruvate-flavodoxin oxidoreductase activity
DMT42_RS22910	COG0674	pyruvate-flavodoxin oxidoreductase activity
DMT42_RS22910	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DMT42_RS22930	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMT42_RS22935	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMT42_RS22940	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMT42_RS22945	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DMT42_RS22950	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMT42_RS22955	COG0839	Belongs to the complex I subunit 6 family
DMT42_RS22960	COG0713	ATP synthesis coupled electron transport
DMT42_RS22965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DMT42_RS22975	COG1007	ATP synthesis coupled electron transport
DMT42_RS22980	COG0501	Belongs to the peptidase M48B family
DMT42_RS22985	COG3304	Inner membrane component domain
DMT42_RS22995	COG2261	transglycosylase associated protein
DMT42_RS23000	COG1666	GTP binding
DMT42_RS23015	COG4191	Histidine kinase
DMT42_RS23035	COG0702	epimerase
DMT42_RS23040	COG0402	S-adenosylhomocysteine deaminase activity
DMT42_RS23055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DMT42_RS23060	COG2030	dehydratase
DMT42_RS23075	COG0477	Major facilitator Superfamily
DMT42_RS23085	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DMT42_RS23090	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DMT42_RS23095	COG0436	Aminotransferase
DMT42_RS23110	COG0250	Participates in transcription elongation, termination and antitermination
DMT42_RS23115	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DMT42_RS23120	COG0081	regulation of translation
DMT42_RS23150	COG0085	RNA polymerase activity
DMT42_RS23155	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DMT42_RS23170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DMT42_RS23240	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DMT42_RS23245	COG0049	tRNA binding
DMT42_RS23250	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DMT42_RS23315	COG0051	transcription antitermination factor activity, RNA binding
DMT42_RS23320	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DMT42_RS23325	COG0088	Forms part of the polypeptide exit tunnel
DMT42_RS23330	COG0089	rRNA binding
DMT42_RS23335	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DMT42_RS23340	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DMT42_RS23345	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DMT42_RS23350	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DMT42_RS23355	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DMT42_RS23360	COG0255	Belongs to the universal ribosomal protein uL29 family
DMT42_RS23365	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DMT42_RS23370	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DMT42_RS23375	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DMT42_RS23380	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DMT42_RS23385	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DMT42_RS23395	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DMT42_RS23400	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DMT42_RS23405	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DMT42_RS23410	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DMT42_RS23415	COG1841	ribosomal large subunit assembly
DMT42_RS23420	COG0200	Binds to the 23S rRNA
DMT42_RS23425	COG0201	protein transport
DMT42_RS23430	COG0563	adenylate kinase activity
DMT42_RS23440	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DMT42_RS23445	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DMT42_RS23450	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DMT42_RS23455	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DMT42_RS23460	COG0202	RNA polymerase activity
DMT42_RS23465	COG0203	ribosomal protein L17
DMT42_RS23470	COG0101	tRNA pseudouridine synthase activity
DMT42_RS23480	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DMT42_RS23485	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DMT42_RS23490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMT42_RS23500	COG1072	(Pantothenic acid kinase))
DMT42_RS23505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DMT42_RS23520	COG0736	holo-[acyl-carrier-protein] synthase activity
DMT42_RS23535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMT42_RS23545	COG0802	atpase or kinase
DMT42_RS23570	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DMT42_RS23590	COG1609	Transcriptional regulator
DMT42_RS23605	COG4941	Belongs to the sigma-70 factor family
DMT42_RS23615	COG0726	polysaccharide deacetylase
DMT42_RS23620	COG0726	polysaccharide deacetylase
DMT42_RS23625	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DMT42_RS23630	COG0459	protein refolding
DMT42_RS23640	COG4221	oxidoreductase activity
DMT42_RS23650	COG0583	DNA-binding transcription factor activity
DMT42_RS23665	COG1595	DNA-templated transcription, initiation
DMT42_RS23675	COG0516	GMP reductase activity
DMT42_RS23685	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DMT42_RS23700	COG0515	serine threonine protein kinase
DMT42_RS23705	COG0515	serine threonine protein kinase
DMT42_RS23705	COG2815	serine threonine protein kinase
DMT42_RS23710	COG0515	serine threonine protein kinase
DMT42_RS23715	COG0515	serine threonine protein kinase
DMT42_RS23720	COG1012	belongs to the aldehyde dehydrogenase family
DMT42_RS23745	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DMT42_RS23745	COG0519	Catalyzes the synthesis of GMP from XMP
DMT42_RS23790	COG2197	response regulator
DMT42_RS23825	COG0739	heme binding
DMT42_RS23835	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMT42_RS23835	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMT42_RS23850	COG0714	Associated with various cellular activities
DMT42_RS23855	COG2425	protein containing a von Willebrand factor type A (vWA) domain
DMT42_RS23860	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DMT42_RS23880	COG0045	succinate-CoA ligase (ADP-forming) activity
DMT42_RS23910	COG0138	bifunctional purine biosynthesis protein purh
DMT42_RS23920	COG2815	serine threonine protein kinase
DMT42_RS23920	COG0515	serine threonine protein kinase
DMT42_RS23935	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DMT42_RS23950	COG0039	L-malate dehydrogenase activity
DMT42_RS23960	COG0477	Major facilitator Superfamily
DMT42_RS23995	COG1012	belongs to the aldehyde dehydrogenase family
DMT42_RS24005	COG4175	Glycine betaine
DMT42_RS24005	COG0517	IMP dehydrogenase activity
DMT42_RS24010	COG4176	ABC-type proline glycine betaine transport system permease component
DMT42_RS24025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DMT42_RS24030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DMT42_RS24035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMT42_RS24045	COG0180	Tryptophanyl-tRNA synthetase
DMT42_RS24060	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMT42_RS24085	COG0671	phosphoesterase, PA-phosphatase related
DMT42_RS24090	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DMT42_RS24095	COG1295	ribonuclease BN
DMT42_RS24100	COG1686	Belongs to the peptidase S11 family
DMT42_RS24120	COG2205	protein histidine kinase activity
DMT42_RS24125	COG0745	RESPONSE REGULATOR receiver
DMT42_RS24130	COG2409	Drug exporters of the RND superfamily
DMT42_RS24180	COG1053	succinate dehydrogenase
DMT42_RS24190	COG2009	succinate dehydrogenase
DMT42_RS24200	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMT42_RS24250	COG1309	transcriptional regulator
DMT42_RS24255	COG0477	Major facilitator Superfamily
DMT42_RS24275	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMT42_RS24275	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMT42_RS24300	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMT42_RS24310	COG1216	Glycosyl transferase, family 2
DMT42_RS24325	COG2089	acid synthase
DMT42_RS24350	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DMT42_RS24350	COG1473	amidohydrolase
DMT42_RS24355	COG1744	ABC transporter substrate-binding protein PnrA-like
DMT42_RS24360	COG3845	ABC transporter
DMT42_RS24365	COG4603	Belongs to the binding-protein-dependent transport system permease family
DMT42_RS24370	COG1079	Belongs to the binding-protein-dependent transport system permease family
DMT42_RS24405	COG0583	DNA-binding transcription factor activity
DMT42_RS24415	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DMT42_RS24440	COG2205	protein histidine kinase activity
DMT42_RS24445	COG0745	RESPONSE REGULATOR receiver
DMT42_RS24450	COG1595	DNA-templated transcription, initiation
DMT42_RS24465	COG1012	belongs to the aldehyde dehydrogenase family
DMT42_RS24470	COG1012	belongs to the aldehyde dehydrogenase family
DMT42_RS24490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMT42_RS24515	COG4770	biotin carboxylase activity
DMT42_RS24525	COG0424	maF-like protein
DMT42_RS24535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DMT42_RS24545	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DMT42_RS24555	COG1024	Enoyl-CoA hydratase
DMT42_RS24585	COG2986	histidine ammonia-lyase
DMT42_RS24600	COG1136	(ABC) transporter
DMT42_RS24605	COG1404	Belongs to the peptidase S8 family
DMT42_RS24615	COG1064	alcohol dehydrogenase
DMT42_RS24645	COG2255	four-way junction helicase activity
DMT42_RS24650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DMT42_RS24665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DMT42_RS24675	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DMT42_RS24695	COG1331	Highly conserved protein containing a thioredoxin domain
DMT42_RS24725	COG1309	transcriptional regulator
DMT42_RS24735	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DMT42_RS24750	COG0436	Aminotransferase
DMT42_RS24765	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DMT42_RS24780	COG1414	Transcriptional regulator
DMT42_RS24790	COG2610	gluconate transmembrane transporter activity
DMT42_RS24820	COG1595	DNA-templated transcription, initiation
DMT42_RS24850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DMT42_RS24885	COG2894	cell division
DMT42_RS24930	COG2885	chlorophyll binding
DMT42_RS24985	COG2226	methyltransferase
DMT42_RS24995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DMT42_RS25000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DMT42_RS25005	COG0741	lytic transglycosylase activity
DMT42_RS25015	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DMT42_RS25020	COG0450	alkyl hydroperoxide reductase
DMT42_RS25035	COG1136	(ABC) transporter
DMT42_RS25060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DMT42_RS25075	COG0114	fumarate hydratase activity
DMT42_RS25080	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DMT42_RS25080	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DMT42_RS25105	COG1722	exodeoxyribonuclease VII activity
DMT42_RS25110	COG1570	exodeoxyribonuclease VII activity
DMT42_RS25115	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DMT42_RS25130	COG0012	GTP binding
DMT42_RS25170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DMT42_RS25195	COG4585	Histidine kinase
DMT42_RS25200	COG0577	efflux transmembrane transporter activity
DMT42_RS25200	COG1136	(ABC) transporter
DMT42_RS25215	COG0318	PFAM AMP-dependent synthetase and ligase
DMT42_RS25260	COG2091	lysine biosynthetic process via aminoadipic acid
DMT42_RS25265	COG3629	intracellular signal transduction
DMT42_RS25265	COG3903	Transcriptional regulator
DMT42_RS25285	COG1216	Glycosyl transferase, family 2
DMT42_RS25285	COG0463	Glycosyl transferase, family 2
DMT42_RS25295	COG3831	ATPase activity
DMT42_RS25300	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DMT42_RS25305	COG0583	DNA-binding transcription factor activity
DMT42_RS25385	COG1217	gtp-binding protein TYPA
DMT42_RS25390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMT42_RS25395	COG0747	negative chemotaxis
DMT42_RS25400	COG0601	transmembrane transport
DMT42_RS25405	COG0444	Belongs to the ABC transporter superfamily
DMT42_RS25410	COG4608	Belongs to the ABC transporter superfamily
DMT42_RS25420	COG0601	transmembrane transport
DMT42_RS25425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMT42_RS25435	COG4608	Belongs to the ABC transporter superfamily
DMT42_RS25450	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DMT42_RS25465	COG1131	(ABC) transporter
DMT42_RS25475	COG4585	Histidine kinase
DMT42_RS25490	COG2197	response regulator
DMT42_RS25530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMT42_RS25540	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DMT42_RS25550	COG0519	Catalyzes the synthesis of GMP from XMP
DMT42_RS25555	COG1024	Enoyl-CoA hydratase
DMT42_RS25570	COG1595	DNA-templated transcription, initiation
DMT42_RS25580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMT42_RS25585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DMT42_RS25620	COG0598	Magnesium transport protein CorA
DMT42_RS25630	COG2814	Major facilitator Superfamily
DMT42_RS25645	COG2095	MarC family integral membrane protein
DMT42_RS25655	COG1432	Conserved Protein
DMT42_RS25665	COG0513	Belongs to the DEAD box helicase family
DMT42_RS25710	COG0747	negative chemotaxis
DMT42_RS25715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMT42_RS25720	COG0601	transmembrane transport
DMT42_RS25810	COG0210	DNA helicase
DMT42_RS25815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMT42_RS25855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DMT42_RS25905	COG3480	Lon protease (S16) C-terminal proteolytic domain
DMT42_RS25915	COG1615	UPF0182 protein
DMT42_RS25945	COG0753	catalase activity
DMT42_RS25955	COG0483	inositol monophosphate 1-phosphatase activity
DMT42_RS25970	COG2076	Multidrug Resistance protein
DMT42_RS25975	COG1162	GTPase activity
DMT42_RS25980	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DMT42_RS25990	COG2135	peptidase activity
DMT42_RS26000	COG1595	DNA-templated transcription, initiation
DMT42_RS26005	COG5662	AntiSigma factor
DMT42_RS26010	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DMT42_RS26010	COG2199	diguanylate cyclase activity
DMT42_RS26025	COG0242	peptide deformylase activity
DMT42_RS26035	COG2124	cytochrome p450
DMT42_RS26080	COG2188	Transcriptional regulator
DMT42_RS26085	COG2182	Extracellular solute-binding protein
DMT42_RS26090	COG1175	transmembrane transport
DMT42_RS26095	COG0395	ABC-type sugar transport system, permease component
DMT42_RS26100	COG1472	Belongs to the glycosyl hydrolase 3 family
DMT42_RS26105	COG0363	glucosamine-6-phosphate deaminase activity
DMT42_RS26110	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS26130	COG1597	lipid kinase activity
DMT42_RS26160	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DMT42_RS26170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DMT42_RS26175	COG0142	geranyltranstransferase activity
DMT42_RS26180	COG0456	acetyltransferase
DMT42_RS26195	COG4941	Belongs to the sigma-70 factor family
DMT42_RS26250	COG1126	abc transporter atp-binding protein
DMT42_RS26255	COG0765	amino acid transport
DMT42_RS26265	COG0281	malic enzyme
DMT42_RS26270	COG0604	alcohol dehydrogenase
DMT42_RS26335	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMT42_RS26335	COG0567	Dehydrogenase, E1 component
DMT42_RS26340	COG2205	protein histidine kinase activity
DMT42_RS26345	COG0745	RESPONSE REGULATOR receiver
DMT42_RS26365	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DMT42_RS26425	COG5002	protein histidine kinase activity
DMT42_RS26460	COG1309	transcriptional regulator
DMT42_RS26490	COG2205	protein histidine kinase activity
DMT42_RS26510	COG3285	dna ligase
DMT42_RS26510	COG1793	dna ligase
DMT42_RS26515	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DMT42_RS26545	COG0745	RESPONSE REGULATOR receiver
DMT42_RS26550	COG0018	arginyl-trna synthetase
DMT42_RS26555	COG0019	diaminopimelate decarboxylase activity
DMT42_RS26560	COG0460	homoserine dehydrogenase
DMT42_RS26565	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DMT42_RS26570	COG0083	homoserine kinase activity
DMT42_RS26585	COG0254	rRNA binding
DMT42_RS26590	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DMT42_RS26595	COG2890	protein-(glutamine-N5) methyltransferase activity
DMT42_RS26605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMT42_RS26615	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMT42_RS26620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DMT42_RS26635	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DMT42_RS26640	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DMT42_RS26645	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DMT42_RS26650	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DMT42_RS26655	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DMT42_RS26660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DMT42_RS26665	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DMT42_RS26680	COG2197	response regulator
DMT42_RS26685	COG4585	Histidine kinase
DMT42_RS26720	COG1250	3-hydroxyacyl-CoA dehydrogenase
DMT42_RS26730	COG4133	protoheme IX ABC transporter activity
DMT42_RS26735	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DMT42_RS26770	COG1131	(ABC) transporter
DMT42_RS26790	COG0183	Belongs to the thiolase family
DMT42_RS26865	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMT42_RS26865	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMT42_RS26910	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DMT42_RS26915	COG0857	belongs to the CobB CobQ family
DMT42_RS26915	COG0280	phosphate acetyltransferase
DMT42_RS26920	COG0205	6-phosphofructokinase activity
DMT42_RS26930	COG0395	ABC-type sugar transport system, permease component
DMT42_RS26935	COG1175	transmembrane transport
DMT42_RS26965	COG3903	Transcriptional regulator
DMT42_RS26965	COG3629	intracellular signal transduction
DMT42_RS26970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DMT42_RS26980	COG3903	Transcriptional regulator
DMT42_RS26980	COG3629	intracellular signal transduction
DMT42_RS26985	COG4565	transcriptional regulatory protein
DMT42_RS26990	COG3290	protein histidine kinase activity
DMT42_RS26995	COG1301	dicarboxylic acid transport
DMT42_RS27005	COG0477	Major facilitator Superfamily
DMT42_RS27020	COG0667	Aldo Keto reductase
DMT42_RS27030	COG1522	sequence-specific DNA binding
DMT42_RS27040	COG3118	belongs to the thioredoxin family
DMT42_RS27050	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DMT42_RS27055	COG3281	Trehalose synthase
DMT42_RS27060	COG0366	Alpha amylase catalytic
DMT42_RS27065	COG0366	Alpha amylase catalytic
DMT42_RS27070	COG0058	SHG alpha-glucan phosphorylase activity
DMT42_RS27105	COG1132	(ABC) transporter
DMT42_RS27110	COG1132	(ABC) transporter
DMT42_RS27125	COG1376	ErfK ybiS ycfS ynhG family protein
DMT42_RS27130	COG1376	ErfK ybiS ycfS ynhG family protein
DMT42_RS27155	COG1024	Enoyl-CoA hydratase
DMT42_RS27185	COG1119	ATPase activity
DMT42_RS27190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMT42_RS27200	COG2207	Transcriptional regulator
DMT42_RS27205	COG0604	alcohol dehydrogenase
DMT42_RS27205	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS27205	COG3321	synthase
DMT42_RS27220	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMT42_RS27230	COG1760	l-serine dehydratase
DMT42_RS27235	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMT42_RS27240	COG0509	glycine decarboxylation via glycine cleavage system
DMT42_RS27245	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DMT42_RS27265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMT42_RS27280	COG0444	Belongs to the ABC transporter superfamily
DMT42_RS27285	COG4608	Belongs to the ABC transporter superfamily
DMT42_RS27290	COG2860	membrane
DMT42_RS27310	COG2378	regulation of single-species biofilm formation
DMT42_RS27340	COG0482	sulfurtransferase activity
DMT42_RS27355	COG1611	Belongs to the LOG family
DMT42_RS27360	COG4221	oxidoreductase activity
DMT42_RS27370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DMT42_RS27385	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMT42_RS27390	COG0154	amidase activity
DMT42_RS27400	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMT42_RS27415	COG2409	Drug exporters of the RND superfamily
DMT42_RS27420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DMT42_RS27435	COG1672	PFAM Archaeal ATPase
DMT42_RS27435	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DMT42_RS27445	COG2133	pyrroloquinoline quinone binding
DMT42_RS27450	COG0667	Aldo Keto reductase
DMT42_RS27460	COG5001	Diguanylate cyclase
DMT42_RS27470	COG0440	acetolactate synthase activity
DMT42_RS27475	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DMT42_RS27480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DMT42_RS27485	COG0477	Major facilitator Superfamily
DMT42_RS27500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMT42_RS27520	COG2508	Transcriptional regulator
DMT42_RS27525	COG0506	proline dehydrogenase activity
DMT42_RS27530	COG1012	belongs to the aldehyde dehydrogenase family
DMT42_RS27540	COG0596	Alpha beta hydrolase
DMT42_RS27545	COG2130	NADP-dependent
DMT42_RS27550	COG0583	DNA-binding transcription factor activity
DMT42_RS27560	COG0473	3-isopropylmalate dehydrogenase activity
DMT42_RS27565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DMT42_RS27575	COG0832	Belongs to the urease beta subunit family
DMT42_RS27575	COG0831	urea catabolic process
DMT42_RS27580	COG0804	urea catabolic process
DMT42_RS27585	COG2957	Belongs to the agmatine deiminase family
DMT42_RS27600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMT42_RS27630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DMT42_RS27655	COG2018	Roadblock/LC7 domain
DMT42_RS27675	COG2018	Roadblock/LC7 domain
DMT42_RS27680	COG5002	protein histidine kinase activity
DMT42_RS27690	COG0179	Fumarylacetoacetate (FAA) hydrolase
DMT42_RS27695	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMT42_RS27750	COG1414	Transcriptional regulator
DMT42_RS27755	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DMT42_RS27760	COG0066	3-isopropylmalate dehydratase activity
DMT42_RS27770	COG0776	regulation of translation
DMT42_RS27785	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DMT42_RS27790	COG1181	Belongs to the D-alanine--D-alanine ligase family
DMT42_RS27810	COG0351	phosphomethylpyrimidine kinase
DMT42_RS27825	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DMT42_RS27830	COG1461	Dihydroxyacetone kinase
DMT42_RS27840	COG0326	Molecular chaperone. Has ATPase activity
DMT42_RS27850	COG0742	ribosomal rna small subunit methyltransferase
DMT42_RS27855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DMT42_RS27870	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DMT42_RS27875	COG0571	ribonuclease III activity
DMT42_RS27880	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DMT42_RS27885	COG1733	regulation of RNA biosynthetic process
DMT42_RS27905	COG2340	Cysteine-rich secretory protein family
DMT42_RS27910	COG1254	Belongs to the acylphosphatase family
DMT42_RS27920	COG1196	nuclear chromosome segregation
DMT42_RS27925	COG0477	Major facilitator Superfamily
DMT42_RS27960	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DMT42_RS27970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DMT42_RS27980	COG0442	prolyl-tRNA aminoacylation
DMT42_RS27990	COG0228	four-way junction DNA binding
DMT42_RS27995	COG1837	Belongs to the UPF0109 family
DMT42_RS28000	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DMT42_RS28005	COG0336	Belongs to the RNA methyltransferase TrmD family
DMT42_RS28010	COG0335	large ribosomal subunit rRNA binding
DMT42_RS28045	COG0792	nuclease activity
DMT42_RS28060	COG1191	sigma factor activity
DMT42_RS28070	COG4942	peptidase
DMT42_RS28075	COG0052	Belongs to the universal ribosomal protein uS2 family
DMT42_RS28080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DMT42_RS28085	COG0528	UMP kinase activity
DMT42_RS28090	COG0233	cytoplasmic translational termination
DMT42_RS28095	COG0575	Belongs to the CDS family
DMT42_RS28130	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DMT42_RS28140	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DMT42_RS28145	COG3842	ATPase activity
DMT42_RS28175	COG1136	(ABC) transporter
DMT42_RS28180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DMT42_RS28190	COG1012	belongs to the aldehyde dehydrogenase family
DMT42_RS28210	COG1733	regulation of RNA biosynthetic process
DMT42_RS28225	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DMT42_RS28250	COG3842	ATPase activity
DMT42_RS28255	COG1176	ABC-type spermidine putrescine transport system, permease component I
DMT42_RS28260	COG1177	transmembrane transport
DMT42_RS28265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DMT42_RS28295	COG2508	Transcriptional regulator
DMT42_RS28300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DMT42_RS28305	COG1012	belongs to the aldehyde dehydrogenase family
DMT42_RS28325	COG1653	transport
DMT42_RS28330	COG4209	transmembrane transport
DMT42_RS28335	COG0395	ABC-type sugar transport system, permease component
DMT42_RS28370	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DMT42_RS28375	COG0750	zinc metalloprotease
DMT42_RS28380	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DMT42_RS28395	COG0442	prolyl-tRNA aminoacylation
DMT42_RS28420	COG0779	Required for maturation of 30S ribosomal subunits
DMT42_RS28435	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DMT42_RS28445	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DMT42_RS28450	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DMT42_RS28465	COG0455	bacterial-type flagellum organization
DMT42_RS28480	COG3266	domain, Protein
DMT42_RS28485	COG1404	Belongs to the peptidase S8 family
DMT42_RS28525	COG1674	ftsk spoiiie
DMT42_RS28545	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DMT42_RS28550	COG1185	polyribonucleotide nucleotidyltransferase activity
DMT42_RS28555	COG0612	Peptidase, M16
DMT42_RS28560	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DMT42_RS28580	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DMT42_RS28585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMT42_RS28590	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DMT42_RS28625	COG2208	phosphoserine phosphatase activity
DMT42_RS28625	COG2770	Histidine kinase
DMT42_RS28635	COG3850	Histidine kinase
DMT42_RS28635	COG4999	Histidine kinase
DMT42_RS28635	COG3437	response regulator, receiver
DMT42_RS28635	COG2205	protein histidine kinase activity
DMT42_RS28645	COG1674	ftsk spoiiie
DMT42_RS28655	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMT42_RS28665	COG1546	Belongs to the CinA family
DMT42_RS28665	COG1058	Belongs to the CinA family
DMT42_RS28670	COG1396	sequence-specific DNA binding
DMT42_RS28675	COG0783	Belongs to the Dps family
DMT42_RS28685	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DMT42_RS28690	COG1201	RNA secondary structure unwinding
DMT42_RS28695	COG1917	Cupin 2, conserved barrel domain protein
DMT42_RS28695	COG2207	Transcriptional regulator
DMT42_RS28730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DMT42_RS28750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DMT42_RS28755	COG0765	amino acid transport
DMT42_RS28760	COG0765	amino acid transport
DMT42_RS28765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMT42_RS28770	COG1126	abc transporter atp-binding protein
DMT42_RS28775	COG0745	RESPONSE REGULATOR receiver
DMT42_RS28780	COG2205	protein histidine kinase activity
DMT42_RS28785	COG2358	TRAP transporter, solute receptor (TAXI family
DMT42_RS28810	COG3851	Histidine kinase
DMT42_RS28815	COG2197	response regulator
DMT42_RS28825	COG5297	Belongs to the glycosyl hydrolase family 6
DMT42_RS28830	COG1472	Belongs to the glycosyl hydrolase 3 family
DMT42_RS28845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMT42_RS28865	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DMT42_RS28875	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DMT42_RS28880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DMT42_RS28890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DMT42_RS28920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DMT42_RS28925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DMT42_RS28930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DMT42_RS28950	COG0588	phosphoglycerate mutase activity
DMT42_RS28970	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DMT42_RS28985	COG0514	ATP-dependent DNA helicase (RecQ)
DMT42_RS29010	COG2186	Transcriptional regulator
DMT42_RS29015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMT42_RS29030	COG0187	DNA topoisomerase II activity
DMT42_RS29040	COG4585	Histidine kinase
DMT42_RS29045	COG2197	response regulator
DMT42_RS29055	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMT42_RS29060	COG4565	transcriptional regulatory protein
DMT42_RS29070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMT42_RS29080	COG4565	transcriptional regulatory protein
DMT42_RS29085	COG3290	protein histidine kinase activity
DMT42_RS29100	COG0372	Belongs to the citrate synthase family
DMT42_RS29125	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMT42_RS29130	COG0612	Peptidase, M16
DMT42_RS29145	COG1802	Transcriptional regulator
DMT42_RS29150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DMT42_RS29175	COG1435	thymidine kinase activity
DMT42_RS29205	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DMT42_RS29215	COG0745	RESPONSE REGULATOR receiver
DMT42_RS29220	COG2205	protein histidine kinase activity
DMT42_RS29245	COG0756	dUTP diphosphatase activity
DMT42_RS29260	COG4591	ABC-type transport system involved in lipoprotein release permease component
DMT42_RS29260	COG1136	(ABC) transporter
DMT42_RS29290	COG0569	domain protein
DMT42_RS29295	COG0531	amino acid
DMT42_RS29300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DMT42_RS29395	COG3693	PFAM glycoside hydrolase, family 10
DMT42_RS29400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DMT42_RS29405	COG0277	FAD linked oxidase domain protein
DMT42_RS29405	COG0247	lactate metabolic process
DMT42_RS29410	COG1799	cell septum assembly
DMT42_RS29445	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DMT42_RS29460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DMT42_RS29465	COG0531	amino acid
DMT42_RS29475	COG1024	Enoyl-CoA hydratase
DMT42_RS29535	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DMT42_RS29545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DMT42_RS29555	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DMT42_RS29565	COG3537	Alpha-1,2-mannosidase
DMT42_RS29580	COG1653	transport
DMT42_RS29585	COG1175	transmembrane transport
DMT42_RS29590	COG0395	ABC-type sugar transport system, permease component
DMT42_RS29595	COG1940	carbohydrate kinase activity
DMT42_RS29600	COG4213	ABC transporter substrate-binding protein
DMT42_RS29610	COG4214	carbohydrate transport
DMT42_RS29615	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMT42_RS29620	COG0531	amino acid
DMT42_RS29635	COG1024	Enoyl-CoA hydratase
DMT42_RS29635	COG1250	3-hydroxyacyl-CoA dehydrogenase
DMT42_RS29640	COG0183	Belongs to the thiolase family
DMT42_RS29645	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DMT42_RS29665	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DMT42_RS29680	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMT42_RS29690	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DMT42_RS29695	COG3253	May function as heme-dependent peroxidase
DMT42_RS29715	COG3220	belongs to the UPF0276 family
DMT42_RS29725	COG1136	(ABC) transporter
DMT42_RS29745	COG0723	plastoquinol--plastocyanin reductase activity
DMT42_RS29745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DMT42_RS29755	COG0330	HflC and HflK could
DMT42_RS29790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DMT42_RS29795	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DMT42_RS29805	COG1174	glycine betaine transport
DMT42_RS29840	COG1404	Belongs to the peptidase S8 family
DMT42_RS29880	COG0504	CTP synthase activity
DMT42_RS29895	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DMT42_RS29905	COG3173	Aminoglycoside phosphotransferase
DMT42_RS29935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMT42_RS29940	COG0583	DNA-binding transcription factor activity
DMT42_RS29985	COG0583	DNA-binding transcription factor activity
DMT42_RS29995	COG1175	transmembrane transport
DMT42_RS30020	COG2409	Drug exporters of the RND superfamily
DMT42_RS30035	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DMT42_RS30055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMT42_RS30060	COG1116	anion transmembrane transporter activity
DMT42_RS30060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DMT42_RS30085	COG0529	Catalyzes the synthesis of activated sulfate
DMT42_RS30090	COG0175	sulfate reduction
DMT42_RS30120	COG1960	acyl-CoA dehydrogenase activity
DMT42_RS30160	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DMT42_RS30185	COG2040	homocysteine
DMT42_RS30215	COG1309	transcriptional regulator
DMT42_RS30230	COG2197	response regulator
DMT42_RS30245	COG0596	Alpha beta hydrolase
DMT42_RS30255	COG0477	Major facilitator Superfamily
DMT42_RS30260	COG0431	NADPH-dependent FMN reductase
DMT42_RS30280	COG1175	transmembrane transport
DMT42_RS30295	COG0277	FAD linked oxidase domain protein
DMT42_RS30315	COG1162	GTPase activity
DMT42_RS30325	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DMT42_RS30350	COG0028	Belongs to the TPP enzyme family
DMT42_RS30370	COG1802	Transcriptional regulator
DMT42_RS30385	COG3835	regulator
DMT42_RS30400	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DMT42_RS30405	COG2252	PERMEase
DMT42_RS30435	COG1088	dTDP-glucose 4,6-dehydratase activity
DMT42_RS30440	COG2192	nodulation
DMT42_RS30450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DMT42_RS30465	COG0438	transferase activity, transferring glycosyl groups
DMT42_RS30470	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DMT42_RS30475	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMT42_RS30475	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DMT42_RS30520	COG0745	RESPONSE REGULATOR receiver
DMT42_RS30525	COG5002	protein histidine kinase activity
DMT42_RS30565	COG2197	response regulator
DMT42_RS30570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DMT42_RS30575	COG0318	PFAM AMP-dependent synthetase and ligase
DMT42_RS30585	COG3960	tartronate-semialdehyde synthase activity
DMT42_RS30600	COG0753	catalase activity
DMT42_RS30605	COG2084	Dehydrogenase
DMT42_RS30610	COG3622	Belongs to the hyi family
DMT42_RS30630	COG2351	hydroxyisourate hydrolase activity
DMT42_RS30640	COG2233	PERMEase
DMT42_RS30650	COG2233	PERMEase
DMT42_RS30665	COG0702	epimerase
DMT42_RS30680	COG0406	alpha-ribazole phosphatase activity
DMT42_RS30685	COG2409	Drug exporters of the RND superfamily
DMT42_RS30690	COG3321	synthase
DMT42_RS30690	COG0604	alcohol dehydrogenase
DMT42_RS30700	COG0436	Aminotransferase
DMT42_RS30745	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DMT42_RS30750	COG0746	molybdenum cofactor guanylyltransferase activity
DMT42_RS30760	COG1414	Transcriptional regulator
DMT42_RS30765	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DMT42_RS30770	COG4266	Belongs to the allantoicase family
DMT42_RS30775	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS30785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMT42_RS30785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMT42_RS30790	COG2197	response regulator
DMT42_RS30795	COG3851	Histidine kinase
DMT42_RS30805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DMT42_RS30840	COG4585	Histidine kinase
DMT42_RS30845	COG2197	response regulator
DMT42_RS30860	COG0673	inositol 2-dehydrogenase activity
DMT42_RS30865	COG2188	Transcriptional regulator
DMT42_RS30885	COG1940	carbohydrate kinase activity
DMT42_RS30895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DMT42_RS30950	COG0151	Belongs to the GarS family
DMT42_RS30955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMT42_RS30955	COG0574	Belongs to the PEP-utilizing enzyme family
DMT42_RS30975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DMT42_RS30995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DMT42_RS31000	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DMT42_RS31020	COG1126	abc transporter atp-binding protein
DMT42_RS31030	COG0405	Gamma-glutamyltransferase
DMT42_RS31035	COG0542	response to heat
DMT42_RS31060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DMT42_RS31075	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DMT42_RS31080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMT42_RS31085	COG1953	Uracil, thiamine, allantoin
DMT42_RS31100	COG4585	Histidine kinase
DMT42_RS31105	COG2197	response regulator
DMT42_RS31120	COG0483	inositol monophosphate 1-phosphatase activity
DMT42_RS31140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DMT42_RS31155	COG2814	Major facilitator Superfamily
DMT42_RS31160	COG0640	Transcriptional regulator
DMT42_RS31185	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DMT42_RS31195	COG0494	nUDIX hydrolase
DMT42_RS31205	COG1929	Belongs to the glycerate kinase type-1 family
DMT42_RS31215	COG0688	phosphatidylethanolamine metabolic process
DMT42_RS31220	COG1960	acyl-CoA dehydrogenase activity
DMT42_RS31235	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMT42_RS31235	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMT42_RS31250	COG1250	3-hydroxyacyl-CoA dehydrogenase
DMT42_RS31260	COG0456	acetyltransferase
DMT42_RS31270	COG0596	Alpha beta hydrolase
DMT42_RS31300	COG2362	D-Aminopeptidase
DMT42_RS31305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMT42_RS31310	COG0823	Involved in the tonB-independent uptake of proteins
DMT42_RS31310	COG1506	peptidase
DMT42_RS31310	COG4946	Tricorn protease homolog
DMT42_RS31315	COG1619	proteins homologs of microcin C7 resistance protein MccF
DMT42_RS31340	COG4221	oxidoreductase activity
DMT42_RS31345	COG4948	Mandelate Racemase Muconate Lactonizing
DMT42_RS31350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMT42_RS31365	COG1793	dna ligase
DMT42_RS31365	COG3285	dna ligase
DMT42_RS31425	COG2226	methyltransferase
DMT42_RS31435	COG0488	(ABC) transporter
DMT42_RS31450	COG0693	protein deglycase activity
DMT42_RS31470	COG0028	Belongs to the TPP enzyme family
DMT42_RS31495	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DMT42_RS31510	COG0531	amino acid
DMT42_RS31520	COG0443	Heat shock 70 kDa protein
DMT42_RS31550	COG2154	pterin-4-alpha-carbinolamine dehydratase
DMT42_RS31555	COG2226	methyltransferase
DMT42_RS31570	COG2378	regulation of single-species biofilm formation
DMT42_RS31580	COG5297	Belongs to the glycosyl hydrolase family 6
DMT42_RS31580	COG4733	cellulase activity
DMT42_RS31585	COG5297	Belongs to the glycosyl hydrolase family 6
DMT42_RS31605	COG0656	L-ascorbic acid biosynthetic process
DMT42_RS31615	COG0477	Major facilitator Superfamily
DMT42_RS31645	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DMT42_RS31660	COG0640	Transcriptional regulator
DMT42_RS31665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DMT42_RS31675	COG1940	carbohydrate kinase activity
DMT42_RS31680	COG1129	ABC transporter
DMT42_RS31685	COG1172	Belongs to the binding-protein-dependent transport system permease family
DMT42_RS31695	COG0673	inositol 2-dehydrogenase activity
DMT42_RS31720	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DMT42_RS31775	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DMT42_RS31780	COG0463	Glycosyl transferase, family 2
DMT42_RS31785	COG3707	response regulator
DMT42_RS31805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DMT42_RS31810	COG2182	Extracellular solute-binding protein
DMT42_RS31815	COG1175	transmembrane transport
DMT42_RS31820	COG0395	ABC-type sugar transport system, permease component
DMT42_RS31825	COG2723	6-phospho-beta-galactosidase activity
DMT42_RS31830	COG2273	Hydrolase Family 16
DMT42_RS31860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMT42_RS31885	COG0297	glycogen (starch) synthase activity
DMT42_RS31905	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMT42_RS31915	COG0477	Major facilitator Superfamily
DMT42_RS31925	COG3467	pyridoxamine 5'-phosphate
DMT42_RS31955	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DMT42_RS31960	COG0166	Belongs to the GPI family
DMT42_RS31975	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DMT42_RS32000	COG2409	Drug exporters of the RND superfamily
DMT42_RS32010	COG2197	response regulator
DMT42_RS32025	COG1486	melibiose metabolic process
DMT42_RS32030	COG3469	chitinase activity
DMT42_RS32040	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DMT42_RS32080	COG3842	ATPase activity
DMT42_RS32085	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DMT42_RS32090	COG1176	ABC-type spermidine putrescine transport system, permease component I
DMT42_RS32095	COG1177	transmembrane transport
DMT42_RS32100	COG3511	phospholipase C
DMT42_RS32145	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DMT42_RS32145	COG1672	PFAM Archaeal ATPase
DMT42_RS32155	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DMT42_RS32160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DMT42_RS32165	COG3485	protocatechuate 3,4-dioxygenase
DMT42_RS32175	COG0183	Belongs to the thiolase family
DMT42_RS32195	COG1470	cell adhesion involved in biofilm formation
DMT42_RS32205	COG1793	dna ligase
DMT42_RS32280	COG1834	amidinotransferase
DMT42_RS32290	COG0488	(ABC) transporter
DMT42_RS32295	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DMT42_RS32320	COG1515	deoxyribonuclease V activity
DMT42_RS32330	COG3268	Saccharopine dehydrogenase
DMT42_RS32335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DMT42_RS32340	COG0183	Belongs to the thiolase family
DMT42_RS32345	COG1250	3-hydroxyacyl-CoA dehydrogenase
DMT42_RS32345	COG1024	Enoyl-CoA hydratase
DMT42_RS32355	COG1113	amino acid transport
DMT42_RS32360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMT42_RS32370	COG2936	dipeptidyl-peptidase activity
DMT42_RS32380	COG0488	(ABC) transporter
DMT42_RS32385	COG2183	response to ionizing radiation
DMT42_RS32405	COG1024	Enoyl-CoA hydratase
DMT42_RS32420	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DMT42_RS32460	COG1134	teichoic acid transport
DMT42_RS32465	COG1562	ergosterol biosynthetic process
DMT42_RS32475	COG1233	COG1233 Phytoene dehydrogenase and related
DMT42_RS32485	COG1657	PFAM Prenyltransferase squalene oxidase
DMT42_RS32500	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DMT42_RS32505	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMT42_RS32525	COG2365	Tyrosine phosphatase family
DMT42_RS32535	COG0667	Aldo Keto reductase
DMT42_RS32545	COG2755	lipolytic protein G-D-S-L family
DMT42_RS32560	COG3507	Belongs to the glycosyl hydrolase 43 family
DMT42_RS32565	COG1278	Cold shock
DMT42_RS32570	COG0302	gtp cyclohydrolase
DMT42_RS32590	COG1012	belongs to the aldehyde dehydrogenase family
DMT42_RS32625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMT42_RS32655	COG1063	alcohol dehydrogenase
DMT42_RS32660	COG0156	8-amino-7-oxononanoate synthase activity
DMT42_RS32665	COG0583	DNA-binding transcription factor activity
DMT42_RS32680	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMT42_RS32720	COG0174	glutamine synthetase
DMT42_RS32725	COG0561	phosphatase activity
DMT42_RS32745	COG2267	carboxylic ester hydrolase activity
DMT42_RS32750	COG0183	Belongs to the thiolase family
DMT42_RS32755	COG0318	PFAM AMP-dependent synthetase and ligase
DMT42_RS32790	COG1215	transferase activity, transferring glycosyl groups
DMT42_RS32805	COG1086	Polysaccharide biosynthesis protein
DMT42_RS32810	COG1316	TRANSCRIPTIONal
DMT42_RS32820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DMT42_RS32850	COG0438	transferase activity, transferring glycosyl groups
DMT42_RS32875	COG3387	PFAM Glycoside hydrolase 15-related
DMT42_RS32890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DMT42_RS32895	COG2188	Transcriptional regulator
DMT42_RS32900	COG3962	Belongs to the TPP enzyme family
DMT42_RS32905	COG3718	enzyme involved in inositol metabolism
DMT42_RS32935	COG0673	inositol 2-dehydrogenase activity
DMT42_RS32940	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS32950	COG1609	Transcriptional regulator
DMT42_RS32960	COG0673	inositol 2-dehydrogenase activity
DMT42_RS32985	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DMT42_RS32990	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DMT42_RS32995	COG2828	Protein conserved in bacteria
DMT42_RS33005	COG2814	Major facilitator Superfamily
DMT42_RS33025	COG0477	Major facilitator Superfamily
DMT42_RS33035	COG2814	Major facilitator Superfamily
DMT42_RS33050	COG2368	4-hydroxyphenylacetate
DMT42_RS33060	COG0367	asparagine synthase
DMT42_RS33075	COG0601	transmembrane transport
DMT42_RS33080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMT42_RS33090	COG0747	negative chemotaxis
DMT42_RS33120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMT42_RS33125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMT42_RS33140	COG2197	response regulator
DMT42_RS33165	COG2124	cytochrome p450
DMT42_RS33185	COG0668	transmembrane transport
DMT42_RS33210	COG1024	Enoyl-CoA hydratase
DMT42_RS33240	COG1357	PFAM Pentapeptide repeats (8 copies)
DMT42_RS33265	COG0784	Response regulator, receiver
DMT42_RS33265	COG5002	protein histidine kinase activity
DMT42_RS33265	COG2205	protein histidine kinase activity
DMT42_RS33285	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DMT42_RS33290	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DMT42_RS33295	COG0583	DNA-binding transcription factor activity
DMT42_RS33345	COG0515	serine threonine protein kinase
DMT42_RS33350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DMT42_RS33435	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DMT42_RS33435	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DMT42_RS33470	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DMT42_RS33485	COG1846	Transcriptional regulator
DMT42_RS33490	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DMT42_RS33510	COG0297	glycogen (starch) synthase activity
DMT42_RS33515	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DMT42_RS33525	COG3537	Alpha-1,2-mannosidase
DMT42_RS33545	COG0154	amidase activity
DMT42_RS33555	COG1653	transport
DMT42_RS33560	COG1175	transmembrane transport
DMT42_RS33565	COG0395	ABC-type sugar transport system, permease component
DMT42_RS33605	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DMT42_RS33630	COG0531	amino acid
DMT42_RS33645	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DMT42_RS33645	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DMT42_RS33650	COG0726	polysaccharide deacetylase
DMT42_RS33695	COG0583	DNA-binding transcription factor activity
DMT42_RS33710	COG0583	DNA-binding transcription factor activity
DMT42_RS33720	COG1053	succinate dehydrogenase
DMT42_RS33725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DMT42_RS33750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMT42_RS33770	COG3360	Dodecin
DMT42_RS33785	COG2235	arginine
DMT42_RS33790	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DMT42_RS33795	COG0121	glutamine amidotransferase
DMT42_RS33805	COG3572	ergothioneine biosynthetic process
DMT42_RS33820	COG2268	Band 7 protein
DMT42_RS33875	COG0589	response to stress
DMT42_RS33880	COG2223	nitrite transmembrane transporter activity
DMT42_RS33885	COG2207	Transcriptional regulator
DMT42_RS33890	COG1309	transcriptional regulator
DMT42_RS33895	COG1960	acyl-CoA dehydrogenase activity
DMT42_RS33925	COG1609	Transcriptional regulator
DMT42_RS33940	COG0242	peptide deformylase activity
DMT42_RS34215	COG0305	Participates in initiation and elongation during chromosome replication
DMT42_RS34220	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DMT42_RS34275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DMT42_RS34280	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DMT42_RS34290	COG2192	nodulation
DMT42_RS34295	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DMT42_RS34305	COG0546	phosphoglycolate phosphatase activity
DMT42_RS34355	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DMT42_RS34360	COG3401	FG-GAP repeat protein
DMT42_RS34395	COG0243	molybdopterin cofactor binding
DMT42_RS34420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMT42_RS34430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMT42_RS34435	COG0456	acetyltransferase
DMT42_RS34510	COG1881	PFAM PEBP family protein
DMT42_RS34525	COG0517	IMP dehydrogenase activity
DMT42_RS34550	COG0542	response to heat
DMT42_RS34555	COG0702	epimerase
DMT42_RS34560	COG1733	regulation of RNA biosynthetic process
DMT42_RS34565	COG1556	Lactate utilization protein
DMT42_RS34570	COG1139	Iron-sulfur cluster binding protein
DMT42_RS34575	COG0247	lactate metabolic process
DMT42_RS34580	COG1070	Carbohydrate kinase
DMT42_RS34585	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS34585	COG3347	Dehydrogenase
DMT42_RS34595	COG1129	ABC transporter
DMT42_RS34600	COG1172	Belongs to the binding-protein-dependent transport system permease family
DMT42_RS34605	COG1172	Belongs to the binding-protein-dependent transport system permease family
DMT42_RS34610	COG1879	ABC-type sugar transport system periplasmic component
DMT42_RS34615	COG3254	rhamnose metabolic process
DMT42_RS34625	COG1609	Transcriptional regulator
DMT42_RS34640	COG1595	DNA-templated transcription, initiation
DMT42_RS34650	COG1309	transcriptional regulator
DMT42_RS34660	COG2706	6-phosphogluconolactonase activity
DMT42_RS34690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DMT42_RS34690	COG2124	cytochrome p450
DMT42_RS34730	COG1796	DNA polymerase
DMT42_RS34730	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DMT42_RS34735	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS34780	COG2111	Na H antiporter
DMT42_RS34785	COG1006	Multisubunit Na H antiporter MnhC subunit
DMT42_RS34790	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMT42_RS34835	COG0435	Glutathione S-transferase
DMT42_RS34845	COG2124	cytochrome p450
DMT42_RS34870	COG0667	Aldo Keto reductase
DMT42_RS34900	COG3250	beta-galactosidase activity
DMT42_RS34910	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DMT42_RS34955	COG2890	protein-(glutamine-N5) methyltransferase activity
DMT42_RS34970	COG0248	Ppx GppA phosphatase
DMT42_RS35005	COG2197	response regulator
DMT42_RS35015	COG1132	(ABC) transporter
DMT42_RS35025	COG0515	serine threonine protein kinase
DMT42_RS35035	COG0517	IMP dehydrogenase activity
DMT42_RS35040	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DMT42_RS35050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DMT42_RS35075	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DMT42_RS35125	COG4221	oxidoreductase activity
DMT42_RS35190	COG1309	transcriptional regulator
DMT42_RS35245	COG0531	amino acid
DMT42_RS35260	COG2409	Drug exporters of the RND superfamily
DMT42_RS35270	COG0673	inositol 2-dehydrogenase activity
DMT42_RS35290	COG2508	Transcriptional regulator
DMT42_RS35295	COG0410	ABC transporter
DMT42_RS35300	COG0411	ABC transporter
DMT42_RS35305	COG0559	Belongs to the binding-protein-dependent transport system permease family
DMT42_RS35340	COG1132	(ABC) transporter
DMT42_RS35375	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DMT42_RS35380	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DMT42_RS35385	COG2080	2 iron, 2 sulfur cluster binding
DMT42_RS35425	COG3290	protein histidine kinase activity
DMT42_RS35440	COG0531	amino acid
DMT42_RS35445	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DMT42_RS35450	COG1801	Protein of unknown function DUF72
DMT42_RS35455	COG2723	6-phospho-beta-galactosidase activity
DMT42_RS35460	COG0395	ABC-type sugar transport system, permease component
DMT42_RS35465	COG1175	transmembrane transport
DMT42_RS35470	COG2182	Extracellular solute-binding protein
DMT42_RS35475	COG1501	Belongs to the glycosyl hydrolase 31 family
DMT42_RS35485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DMT42_RS35490	COG0254	rRNA binding
DMT42_RS35530	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DMT42_RS35540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DMT42_RS35545	COG2264	protein methyltransferase activity
DMT42_RS35555	COG0367	asparagine synthase
DMT42_RS35575	COG1051	belongs to the nudix hydrolase family
DMT42_RS35580	COG1470	cell adhesion involved in biofilm formation
DMT42_RS35580	COG0366	Alpha amylase catalytic
DMT42_RS35595	COG0277	FAD linked oxidase domain protein
DMT42_RS35635	COG1295	ribonuclease BN
DMT42_RS35665	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DMT42_RS35735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DMT42_RS35765	COG0477	Major facilitator Superfamily
DMT42_RS35770	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DMT42_RS35775	COG0484	heat shock protein binding
DMT42_RS35780	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DMT42_RS35785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMT42_RS35825	COG1482	cell wall glycoprotein biosynthetic process
DMT42_RS35840	COG0747	negative chemotaxis
DMT42_RS35845	COG0601	transmembrane transport
DMT42_RS35885	COG2205	protein histidine kinase activity
DMT42_RS35910	COG2326	polyphosphate kinase activity
DMT42_RS35945	COG0640	Transcriptional regulator
DMT42_RS35990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DMT42_RS35995	COG0574	Belongs to the PEP-utilizing enzyme family
DMT42_RS35995	COG3848	Pyruvate phosphate dikinase
DMT42_RS36035	COG4977	sequence-specific DNA binding
DMT42_RS36040	COG0494	nUDIX hydrolase
DMT42_RS36050	COG0187	DNA topoisomerase II activity
DMT42_RS36065	COG0714	Associated with various cellular activities
DMT42_RS36080	COG0009	L-threonylcarbamoyladenylate synthase
DMT42_RS36115	COG2226	methyltransferase
DMT42_RS36160	COG0142	geranyltranstransferase activity
DMT42_RS36180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DMT42_RS36195	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS36290	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DMT42_RS36320	COG3655	Transcriptional regulator
DMT42_RS36360	COG0577	efflux transmembrane transporter activity
DMT42_RS36360	COG1136	(ABC) transporter
DMT42_RS36365	COG0577	efflux transmembrane transporter activity
DMT42_RS36370	COG4585	Histidine kinase
DMT42_RS36375	COG2197	response regulator
DMT42_RS36385	COG0783	Belongs to the Dps family
DMT42_RS36470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DMT42_RS36505	COG3708	Transcriptional regulator
DMT42_RS36505	COG2207	Transcriptional regulator
DMT42_RS36520	COG0604	alcohol dehydrogenase
DMT42_RS36520	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS36520	COG3321	synthase
DMT42_RS36540	COG2318	DinB family
DMT42_RS36600	COG1764	response to oxidative stress
DMT42_RS36620	COG0488	(ABC) transporter
DMT42_RS36625	COG0488	(ABC) transporter
DMT42_RS36700	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS36710	COG1309	transcriptional regulator
DMT42_RS36715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DMT42_RS36725	COG3979	chitinase
DMT42_RS36770	COG1028	Short-chain dehydrogenase reductase Sdr
DMT42_RS36775	COG1846	Transcriptional regulator
DMT42_RS36780	COG0697	spore germination
DMT42_RS36795	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DMT42_RS36815	COG2814	Major facilitator Superfamily
DMT42_RS36890	COG1937	Protein conserved in bacteria
DMT42_RS36895	COG0730	response to heat
DMT42_RS36930	COG0657	acetylesterase activity
DMT42_RS36985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DMT42_RS36995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DMT42_RS37030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMT42_RS37070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMT42_RS37080	COG0431	NADPH-dependent FMN reductase
DMT42_RS37130	COG0326	Molecular chaperone. Has ATPase activity
DMT42_RS37200	COG3507	Belongs to the glycosyl hydrolase 43 family
DMT42_RS37265	COG1595	DNA-templated transcription, initiation
DMT42_RS37290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DMT42_RS37310	COG1335	isochorismatase
DMT42_RS37410	COG0702	epimerase