locus-tag	class	description
K1J60_RS00080	COG1595	DNA-templated transcription, initiation
K1J60_RS00100	COG0673	inositol 2-dehydrogenase activity
K1J60_RS00110	COG1609	Transcriptional regulator
K1J60_RS00130	COG3321	synthase
K1J60_RS00130	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS00130	COG0604	alcohol dehydrogenase
K1J60_RS00140	COG3321	synthase
K1J60_RS00140	COG0604	alcohol dehydrogenase
K1J60_RS00170	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K1J60_RS00195	COG0300	oxidoreductase activity
K1J60_RS00195	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS00195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K1J60_RS00195	COG3321	synthase
K1J60_RS00195	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS00270	COG0563	adenylate kinase activity
K1J60_RS00290	COG3507	Belongs to the glycosyl hydrolase 43 family
K1J60_RS00325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K1J60_RS00340	COG0179	Fumarylacetoacetate (FAA) hydrolase
K1J60_RS00350	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS00370	COG0300	oxidoreductase activity
K1J60_RS00400	COG1309	transcriptional regulator
K1J60_RS00415	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K1J60_RS00420	COG0443	Heat shock 70 kDa protein
K1J60_RS00460	COG0800	Aldolase
K1J60_RS00465	COG0395	ABC-type sugar transport system, permease component
K1J60_RS00470	COG1175	transmembrane transport
K1J60_RS00480	COG1609	Transcriptional regulator
K1J60_RS00490	COG4948	Mandelate Racemase Muconate Lactonizing
K1J60_RS00520	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K1J60_RS00530	COG0183	Belongs to the thiolase family
K1J60_RS00535	COG0583	DNA-binding transcription factor activity
K1J60_RS00540	COG0583	DNA-binding transcription factor activity
K1J60_RS00555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K1J60_RS00595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K1J60_RS00615	COG0492	ferredoxin-NADP+ reductase activity
K1J60_RS00630	COG3185	4-Hydroxyphenylpyruvate dioxygenase
K1J60_RS00640	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
K1J60_RS00655	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
K1J60_RS00670	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
K1J60_RS00675	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
K1J60_RS00685	COG5002	protein histidine kinase activity
K1J60_RS00690	COG2018	Roadblock/LC7 domain
K1J60_RS00715	COG1802	Transcriptional regulator
K1J60_RS00730	COG0179	Fumarylacetoacetate (FAA) hydrolase
K1J60_RS00735	COG1063	alcohol dehydrogenase
K1J60_RS00745	COG2814	Major facilitator Superfamily
K1J60_RS00755	COG0205	6-phosphofructokinase activity
K1J60_RS00800	COG2239	Acts as a magnesium transporter
K1J60_RS00820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K1J60_RS00855	COG0516	GMP reductase activity
K1J60_RS00855	COG0517	IMP dehydrogenase activity
K1J60_RS00885	COG0516	GMP reductase activity
K1J60_RS00885	COG0517	IMP dehydrogenase activity
K1J60_RS00890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K1J60_RS00890	COG1042	CoA-binding domain protein
K1J60_RS00890	COG0045	succinate-CoA ligase (ADP-forming) activity
K1J60_RS00910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K1J60_RS00915	COG0517	IMP dehydrogenase activity
K1J60_RS00915	COG0516	GMP reductase activity
K1J60_RS00960	COG2202	Pas domain
K1J60_RS00960	COG2199	diguanylate cyclase activity
K1J60_RS00960	COG2200	EAL domain
K1J60_RS00980	COG1454	alcohol dehydrogenase
K1J60_RS00980	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS00990	COG1063	alcohol dehydrogenase
K1J60_RS01005	COG0516	GMP reductase activity
K1J60_RS01005	COG0517	IMP dehydrogenase activity
K1J60_RS01015	COG0574	Belongs to the PEP-utilizing enzyme family
K1J60_RS01015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K1J60_RS01035	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
K1J60_RS01040	COG2326	polyphosphate kinase activity
K1J60_RS01065	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K1J60_RS01075	COG0549	Belongs to the carbamate kinase family
K1J60_RS01090	COG0517	IMP dehydrogenase activity
K1J60_RS01090	COG0516	GMP reductase activity
K1J60_RS01105	COG1140	nitrate reductase beta subunit
K1J60_RS01110	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
K1J60_RS01125	COG4716	Myosin-crossreactive antigen
K1J60_RS01130	COG0515	serine threonine protein kinase
K1J60_RS01170	COG0142	geranyltranstransferase activity
K1J60_RS01190	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
K1J60_RS01195	COG0445	tRNA wobble uridine modification
K1J60_RS01225	COG0395	ABC-type sugar transport system, permease component
K1J60_RS01230	COG1175	transmembrane transport
K1J60_RS01235	COG1653	transport
K1J60_RS01240	COG0366	Alpha amylase catalytic
K1J60_RS01250	COG1695	Transcriptional regulator
K1J60_RS01255	COG1136	(ABC) transporter
K1J60_RS01325	COG3467	pyridoxamine 5'-phosphate
K1J60_RS01335	COG1595	DNA-templated transcription, initiation
K1J60_RS01360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K1J60_RS01380	COG5640	endopeptidase activity
K1J60_RS01425	COG4171	peptide transport system, permease
K1J60_RS01435	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K1J60_RS01440	COG1760	l-serine dehydratase
K1J60_RS01455	COG4638	Rieske (2fe-2S)
K1J60_RS01475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K1J60_RS01495	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K1J60_RS01510	COG4176	ABC-type proline glycine betaine transport system permease component
K1J60_RS01515	COG4175	Glycine betaine
K1J60_RS01515	COG0517	IMP dehydrogenase activity
K1J60_RS01520	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS01535	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
K1J60_RS01545	COG4638	Rieske (2fe-2S)
K1J60_RS01550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K1J60_RS01585	COG1609	Transcriptional regulator
K1J60_RS01620	COG1609	Transcriptional regulator
K1J60_RS01635	COG0395	ABC-type sugar transport system, permease component
K1J60_RS01660	COG3655	Transcriptional regulator
K1J60_RS01685	COG0488	(ABC) transporter
K1J60_RS01695	COG2045	Belongs to the ComB family
K1J60_RS01720	COG0513	Belongs to the DEAD box helicase family
K1J60_RS01750	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS01780	COG1233	COG1233 Phytoene dehydrogenase and related
K1J60_RS01800	COG0181	hydroxymethylbilane synthase activity
K1J60_RS01815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K1J60_RS01840	COG2409	Drug exporters of the RND superfamily
K1J60_RS01875	COG3290	protein histidine kinase activity
K1J60_RS01880	COG0673	inositol 2-dehydrogenase activity
K1J60_RS01900	COG0667	Aldo Keto reductase
K1J60_RS01915	COG0009	L-threonylcarbamoyladenylate synthase
K1J60_RS01945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K1J60_RS01960	COG4565	transcriptional regulatory protein
K1J60_RS01965	COG3290	protein histidine kinase activity
K1J60_RS02025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K1J60_RS02035	COG1228	amidohydrolase
K1J60_RS02075	COG2340	Cysteine-rich secretory protein family
K1J60_RS02095	COG0572	uridine kinase
K1J60_RS02110	COG0395	ABC-type sugar transport system, permease component
K1J60_RS02125	COG1940	carbohydrate kinase activity
K1J60_RS02150	COG3851	Histidine kinase
K1J60_RS02160	COG1136	(ABC) transporter
K1J60_RS02170	COG2197	response regulator
K1J60_RS02205	COG1846	Transcriptional regulator
K1J60_RS02205	COG1940	carbohydrate kinase activity
K1J60_RS02210	COG1175	transmembrane transport
K1J60_RS02215	COG0395	ABC-type sugar transport system, permease component
K1J60_RS02220	COG2182	Extracellular solute-binding protein
K1J60_RS02235	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K1J60_RS02270	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS02295	COG1937	Protein conserved in bacteria
K1J60_RS02300	COG1132	(ABC) transporter
K1J60_RS02320	COG1819	glycosyl
K1J60_RS02360	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
K1J60_RS02375	COG0515	serine threonine protein kinase
K1J60_RS02385	COG1132	(ABC) transporter
K1J60_RS02395	COG2197	response regulator
K1J60_RS02425	COG1132	(ABC) transporter
K1J60_RS02455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K1J60_RS02460	COG0747	negative chemotaxis
K1J60_RS02470	COG0248	Ppx GppA phosphatase
K1J60_RS02520	COG3250	beta-galactosidase activity
K1J60_RS02535	COG2207	Transcriptional regulator
K1J60_RS02565	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K1J60_RS02575	COG2197	response regulator
K1J60_RS02585	COG1129	ABC transporter
K1J60_RS02605	COG1846	Transcriptional regulator
K1J60_RS02625	COG0435	Glutathione S-transferase
K1J60_RS02660	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS02675	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K1J60_RS02700	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K1J60_RS02700	COG1796	DNA polymerase
K1J60_RS02740	COG2706	6-phosphogluconolactonase activity
K1J60_RS02760	COG1357	PFAM Pentapeptide repeats (8 copies)
K1J60_RS02775	COG1609	Transcriptional regulator
K1J60_RS02805	COG1129	ABC transporter
K1J60_RS02810	COG4952	isomerase
K1J60_RS02815	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS02815	COG3347	Dehydrogenase
K1J60_RS02820	COG1070	Carbohydrate kinase
K1J60_RS02825	COG0247	lactate metabolic process
K1J60_RS02830	COG1139	Iron-sulfur cluster binding protein
K1J60_RS02835	COG1556	Lactate utilization protein
K1J60_RS02840	COG1573	uracil-dna glycosylase
K1J60_RS02850	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
K1J60_RS02865	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS02875	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS02880	COG1063	alcohol dehydrogenase
K1J60_RS02885	COG0673	inositol 2-dehydrogenase activity
K1J60_RS02900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K1J60_RS02905	COG1120	ATPase activity
K1J60_RS02910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K1J60_RS02915	COG3708	Transcriptional regulator
K1J60_RS02915	COG2207	Transcriptional regulator
K1J60_RS02935	COG0174	glutamine synthetase
K1J60_RS02950	COG4689	acetoacetate decarboxylase
K1J60_RS02955	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS02970	COG1309	transcriptional regulator
K1J60_RS02980	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS02995	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K1J60_RS03015	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
K1J60_RS03045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K1J60_RS03065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K1J60_RS03075	COG1522	sequence-specific DNA binding
K1J60_RS03095	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS03100	COG0183	Belongs to the thiolase family
K1J60_RS03105	COG1024	Enoyl-CoA hydratase
K1J60_RS03110	COG1250	3-hydroxyacyl-CoA dehydrogenase
K1J60_RS03115	COG1024	Enoyl-CoA hydratase
K1J60_RS03120	COG3396	Phenylacetate-CoA oxygenase
K1J60_RS03125	COG3460	Phenylacetate-CoA oxygenase
K1J60_RS03130	COG3396	Phenylacetate-CoA oxygenase
K1J60_RS03135	COG2151	metal-sulfur cluster biosynthetic enzyme
K1J60_RS03140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K1J60_RS03155	COG3321	synthase
K1J60_RS03155	COG0604	alcohol dehydrogenase
K1J60_RS03175	COG1309	transcriptional regulator
K1J60_RS03180	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
K1J60_RS03195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K1J60_RS03200	COG0778	Nitroreductase
K1J60_RS03210	COG4585	Histidine kinase
K1J60_RS03215	COG2197	response regulator
K1J60_RS03245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K1J60_RS03320	COG0723	plastoquinol--plastocyanin reductase activity
K1J60_RS03320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K1J60_RS03330	COG0667	Aldo Keto reductase
K1J60_RS03335	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS03345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K1J60_RS03360	COG3842	ATPase activity
K1J60_RS03375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K1J60_RS03385	COG1414	Transcriptional regulator
K1J60_RS03395	COG0247	lactate metabolic process
K1J60_RS03395	COG0277	FAD linked oxidase domain protein
K1J60_RS03400	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K1J60_RS03490	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS03500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K1J60_RS03510	COG0477	Major facilitator Superfamily
K1J60_RS03520	COG3328	transposase activity
K1J60_RS03525	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS03545	COG1609	Transcriptional regulator
K1J60_RS03550	COG0747	negative chemotaxis
K1J60_RS03560	COG0444	Belongs to the ABC transporter superfamily
K1J60_RS03565	COG4608	Belongs to the ABC transporter superfamily
K1J60_RS03570	COG0596	Alpha beta hydrolase
K1J60_RS03675	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS03705	COG1024	Enoyl-CoA hydratase
K1J60_RS03710	COG0183	Belongs to the thiolase family
K1J60_RS03720	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS03730	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS03735	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS03745	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS03765	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS03770	COG0596	Alpha beta hydrolase
K1J60_RS03815	COG0242	peptide deformylase activity
K1J60_RS03825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K1J60_RS03830	COG1609	Transcriptional regulator
K1J60_RS03835	COG0657	acetylesterase activity
K1J60_RS03855	COG2268	Band 7 protein
K1J60_RS03875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K1J60_RS03880	COG0121	glutamine amidotransferase
K1J60_RS03885	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
K1J60_RS03890	COG3360	Dodecin
K1J60_RS03910	COG0657	acetylesterase activity
K1J60_RS03920	COG2828	Protein conserved in bacteria
K1J60_RS03925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K1J60_RS03930	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K1J60_RS03935	COG2188	Transcriptional regulator
K1J60_RS03950	COG2072	flavoprotein involved in K transport
K1J60_RS03955	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS03965	COG0745	RESPONSE REGULATOR receiver
K1J60_RS03970	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS03985	COG2197	response regulator
K1J60_RS03995	COG2205	protein histidine kinase activity
K1J60_RS04000	COG0745	RESPONSE REGULATOR receiver
K1J60_RS04005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K1J60_RS04005	COG1017	nitric oxide dioxygenase activity
K1J60_RS04015	COG1477	protein flavinylation
K1J60_RS04030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K1J60_RS04050	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K1J60_RS04055	COG1053	succinate dehydrogenase
K1J60_RS04065	COG0583	DNA-binding transcription factor activity
K1J60_RS04115	COG0589	response to stress
K1J60_RS04135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
K1J60_RS04180	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K1J60_RS04185	COG0297	glycogen (starch) synthase activity
K1J60_RS04205	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
K1J60_RS04215	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
K1J60_RS04225	COG1621	beta-fructofuranosidase activity
K1J60_RS04235	COG0395	ABC-type sugar transport system, permease component
K1J60_RS04240	COG1175	transmembrane transport
K1J60_RS04250	COG1609	Transcriptional regulator
K1J60_RS04255	COG1621	beta-fructofuranosidase activity
K1J60_RS04265	COG2080	2 iron, 2 sulfur cluster binding
K1J60_RS04270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
K1J60_RS04275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K1J60_RS04335	COG3386	PFAM SMP-30 Gluconolaconase
K1J60_RS04345	COG0800	Aldolase
K1J60_RS04350	COG4948	Mandelate Racemase Muconate Lactonizing
K1J60_RS04370	COG1175	transmembrane transport
K1J60_RS04375	COG0395	ABC-type sugar transport system, permease component
K1J60_RS04380	COG3250	beta-galactosidase activity
K1J60_RS04410	COG0395	ABC-type sugar transport system, permease component
K1J60_RS04425	COG3250	beta-galactosidase activity
K1J60_RS04440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K1J60_RS04445	COG3485	protocatechuate 3,4-dioxygenase
K1J60_RS04455	COG1414	Transcriptional regulator
K1J60_RS04515	COG0492	ferredoxin-NADP+ reductase activity
K1J60_RS04535	COG3964	amidohydrolase
K1J60_RS04545	COG4213	ABC transporter substrate-binding protein
K1J60_RS04555	COG3201	nicotinamide mononucleotide transporter
K1J60_RS04575	COG0667	Aldo Keto reductase
K1J60_RS04580	COG1079	Belongs to the binding-protein-dependent transport system permease family
K1J60_RS04585	COG4603	Belongs to the binding-protein-dependent transport system permease family
K1J60_RS04590	COG3845	ABC transporter
K1J60_RS04605	COG0402	S-adenosylhomocysteine deaminase activity
K1J60_RS04620	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS04650	COG0477	Major facilitator Superfamily
K1J60_RS04685	COG1132	(ABC) transporter
K1J60_RS04695	COG0668	transmembrane transport
K1J60_RS04700	COG2838	Isocitrate dehydrogenase
K1J60_RS04710	COG1846	Transcriptional regulator
K1J60_RS04750	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K1J60_RS04780	COG2268	Band 7 protein
K1J60_RS04785	COG1585	Membrane protein implicated in regulation of membrane protease activity
K1J60_RS04855	COG1192	Involved in chromosome partitioning
K1J60_RS04880	COG1454	alcohol dehydrogenase
K1J60_RS04885	COG3485	protocatechuate 3,4-dioxygenase
K1J60_RS04935	COG2197	response regulator
K1J60_RS04940	COG4585	Histidine kinase
K1J60_RS04960	COG1013	pyruvate-flavodoxin oxidoreductase activity
K1J60_RS04965	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K1J60_RS04965	COG0674	pyruvate-flavodoxin oxidoreductase activity
K1J60_RS05000	COG2188	Transcriptional regulator
K1J60_RS05035	COG2267	carboxylic ester hydrolase activity
K1J60_RS05050	COG0402	S-adenosylhomocysteine deaminase activity
K1J60_RS05060	COG3387	PFAM Glycoside hydrolase 15-related
K1J60_RS05070	COG4221	oxidoreductase activity
K1J60_RS05075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K1J60_RS05080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K1J60_RS05095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K1J60_RS05100	COG3938	Belongs to the proline racemase family
K1J60_RS05170	COG3959	Transketolase, thiamine diphosphate binding domain
K1J60_RS05175	COG3958	Transketolase
K1J60_RS05195	COG0583	DNA-binding transcription factor activity
K1J60_RS05200	COG0156	8-amino-7-oxononanoate synthase activity
K1J60_RS05205	COG1063	alcohol dehydrogenase
K1J60_RS05240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K1J60_RS05250	COG2755	lipolytic protein G-D-S-L family
K1J60_RS05270	COG2365	Tyrosine phosphatase family
K1J60_RS05290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K1J60_RS05295	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
K1J60_RS05310	COG1657	PFAM Prenyltransferase squalene oxidase
K1J60_RS05320	COG1233	COG1233 Phytoene dehydrogenase and related
K1J60_RS05330	COG1562	ergosterol biosynthetic process
K1J60_RS05335	COG1134	teichoic acid transport
K1J60_RS05355	COG0371	Dehydrogenase
K1J60_RS05385	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
K1J60_RS05395	COG1024	Enoyl-CoA hydratase
K1J60_RS05405	COG4977	sequence-specific DNA binding
K1J60_RS05415	COG2183	response to ionizing radiation
K1J60_RS05420	COG0488	(ABC) transporter
K1J60_RS05435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K1J60_RS05445	COG2936	dipeptidyl-peptidase activity
K1J60_RS05450	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K1J60_RS05475	COG0183	Belongs to the thiolase family
K1J60_RS05480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K1J60_RS05490	COG3268	Saccharopine dehydrogenase
K1J60_RS05500	COG1515	deoxyribonuclease V activity
K1J60_RS05520	COG0488	(ABC) transporter
K1J60_RS05525	COG1834	amidinotransferase
K1J60_RS05590	COG1793	dna ligase
K1J60_RS05610	COG3485	protocatechuate 3,4-dioxygenase
K1J60_RS05615	COG3485	protocatechuate 3,4-dioxygenase
K1J60_RS05620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K1J60_RS05625	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K1J60_RS05660	COG3511	phospholipase C
K1J60_RS05665	COG2205	protein histidine kinase activity
K1J60_RS05695	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS05750	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K1J60_RS05820	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
K1J60_RS06010	COG0242	peptide deformylase activity
K1J60_RS06015	COG0242	peptide deformylase activity
K1J60_RS06045	COG1074	ATP-dependent DNA helicase activity
K1J60_RS06050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K1J60_RS06085	COG1074	ATP-dependent DNA helicase activity
K1J60_RS06260	COG0789	Transcriptional regulator
K1J60_RS06295	COG1742	UPF0060 membrane protein
K1J60_RS06320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K1J60_RS06320	COG0425	Belongs to the sulfur carrier protein TusA family
K1J60_RS06380	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS06430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K1J60_RS06450	COG4106	trans-aconitate 2-methyltransferase activity
K1J60_RS06465	COG2192	nodulation
K1J60_RS06480	COG0546	phosphoglycolate phosphatase activity
K1J60_RS06505	COG1324	tolerance protein
K1J60_RS06560	COG1414	Transcriptional regulator
K1J60_RS06570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K1J60_RS06575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K1J60_RS06625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
K1J60_RS06645	COG1486	melibiose metabolic process
K1J60_RS06650	COG1349	DNA-binding transcription factor activity
K1J60_RS06655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K1J60_RS06675	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K1J60_RS06680	COG3250	beta-galactosidase activity
K1J60_RS06685	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
K1J60_RS06725	COG3119	arylsulfatase activity
K1J60_RS06735	COG0515	serine threonine protein kinase
K1J60_RS06735	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K1J60_RS06765	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K1J60_RS06790	COG1082	Xylose isomerase domain protein TIM barrel
K1J60_RS06790	COG3185	4-Hydroxyphenylpyruvate dioxygenase
K1J60_RS06795	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
K1J60_RS06805	COG0477	Major facilitator Superfamily
K1J60_RS06830	COG0477	Major facilitator Superfamily
K1J60_RS06855	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K1J60_RS06870	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS06890	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K1J60_RS06905	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS06910	COG0673	inositol 2-dehydrogenase activity
K1J60_RS06950	COG2319	Wd-40 repeat
K1J60_RS06950	COG4249	Peptidase C14 caspase catalytic subunit p20
K1J60_RS06965	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K1J60_RS06990	COG0443	Heat shock 70 kDa protein
K1J60_RS07070	COG0515	serine threonine protein kinase
K1J60_RS07075	COG0210	DNA helicase
K1J60_RS07090	COG1414	Transcriptional regulator
K1J60_RS07120	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS07130	COG0045	succinate-CoA ligase (ADP-forming) activity
K1J60_RS07140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K1J60_RS07150	COG2223	nitrite transmembrane transporter activity
K1J60_RS07195	COG3507	Belongs to the glycosyl hydrolase 43 family
K1J60_RS07205	COG0673	inositol 2-dehydrogenase activity
K1J60_RS07215	COG1172	Belongs to the binding-protein-dependent transport system permease family
K1J60_RS07220	COG1129	ABC transporter
K1J60_RS07225	COG1940	carbohydrate kinase activity
K1J60_RS07235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K1J60_RS07270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K1J60_RS07275	COG3383	formate dehydrogenase (NAD+) activity
K1J60_RS07290	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K1J60_RS07325	COG0656	L-ascorbic acid biosynthetic process
K1J60_RS07330	COG4221	oxidoreductase activity
K1J60_RS07335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K1J60_RS07345	COG5297	Belongs to the glycosyl hydrolase family 6
K1J60_RS07350	COG4733	cellulase activity
K1J60_RS07350	COG5297	Belongs to the glycosyl hydrolase family 6
K1J60_RS07365	COG1309	transcriptional regulator
K1J60_RS07370	COG1733	regulation of RNA biosynthetic process
K1J60_RS07390	COG3401	FG-GAP repeat protein
K1J60_RS07400	COG2226	methyltransferase
K1J60_RS07405	COG2154	pterin-4-alpha-carbinolamine dehydratase
K1J60_RS07425	COG0443	Heat shock 70 kDa protein
K1J60_RS07455	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K1J60_RS07495	COG0028	Belongs to the TPP enzyme family
K1J60_RS07505	COG0517	IMP dehydrogenase activity
K1J60_RS07515	COG0693	protein deglycase activity
K1J60_RS07535	COG0488	(ABC) transporter
K1J60_RS07540	COG3842	ATPase activity
K1J60_RS07545	COG1178	ABC-type Fe3 transport system permease component
K1J60_RS07550	COG1840	ABC-type Fe3 transport system, periplasmic component
K1J60_RS07555	COG0745	RESPONSE REGULATOR receiver
K1J60_RS07560	COG5002	protein histidine kinase activity
K1J60_RS07565	COG1597	lipid kinase activity
K1J60_RS07570	COG2226	methyltransferase
K1J60_RS07630	COG1793	dna ligase
K1J60_RS07630	COG3285	dna ligase
K1J60_RS07635	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K1J60_RS07675	COG1619	proteins homologs of microcin C7 resistance protein MccF
K1J60_RS07680	COG1506	peptidase
K1J60_RS07680	COG0823	Involved in the tonB-independent uptake of proteins
K1J60_RS07680	COG4946	Tricorn protease homolog
K1J60_RS07690	COG2362	D-Aminopeptidase
K1J60_RS07720	COG0596	Alpha beta hydrolase
K1J60_RS07735	COG1250	3-hydroxyacyl-CoA dehydrogenase
K1J60_RS07745	COG0604	alcohol dehydrogenase
K1J60_RS07750	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K1J60_RS07750	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K1J60_RS07765	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS07770	COG0688	phosphatidylethanolamine metabolic process
K1J60_RS07785	COG1929	Belongs to the glycerate kinase type-1 family
K1J60_RS07795	COG0494	nUDIX hydrolase
K1J60_RS07805	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K1J60_RS07825	COG0640	Transcriptional regulator
K1J60_RS07835	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
K1J60_RS07870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
K1J60_RS07880	COG0483	inositol monophosphate 1-phosphatase activity
K1J60_RS07905	COG1953	Uracil, thiamine, allantoin
K1J60_RS07915	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K1J60_RS07930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K1J60_RS07955	COG0542	response to heat
K1J60_RS07960	COG0405	Gamma-glutamyltransferase
K1J60_RS07975	COG1126	abc transporter atp-binding protein
K1J60_RS07995	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K1J60_RS08000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K1J60_RS08060	COG0602	queuosine metabolic process
K1J60_RS08065	COG0302	gtp cyclohydrolase
K1J60_RS08080	COG0529	Catalyzes the synthesis of activated sulfate
K1J60_RS08125	COG1228	amidohydrolase
K1J60_RS08185	COG0494	nUDIX hydrolase
K1J60_RS08265	COG0151	Belongs to the GarS family
K1J60_RS08370	COG0501	Belongs to the peptidase M48B family
K1J60_RS08645	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K1J60_RS08655	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K1J60_RS08660	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
K1J60_RS08665	COG2080	2 iron, 2 sulfur cluster binding
K1J60_RS08685	COG1024	Enoyl-CoA hydratase
K1J60_RS08690	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS08705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K1J60_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS08745	COG1063	alcohol dehydrogenase
K1J60_RS08750	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS08755	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS08760	COG2084	Dehydrogenase
K1J60_RS08765	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS08775	COG2079	MmgE PrpD family protein
K1J60_RS08805	COG1129	ABC transporter
K1J60_RS08820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K1J60_RS08825	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
K1J60_RS08830	COG2301	Belongs to the HpcH HpaI aldolase family
K1J60_RS08840	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
K1J60_RS08845	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
K1J60_RS08855	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K1J60_RS08860	COG2181	nitrate reductase activity
K1J60_RS08860	COG0247	lactate metabolic process
K1J60_RS08875	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS08885	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS08900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K1J60_RS08910	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS08915	COG1063	alcohol dehydrogenase
K1J60_RS08920	COG2172	sigma factor antagonist activity
K1J60_RS08920	COG2208	phosphoserine phosphatase activity
K1J60_RS08920	COG1366	Belongs to the anti-sigma-factor antagonist family
K1J60_RS08925	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS08935	COG2186	Transcriptional regulator
K1J60_RS08940	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS08950	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS08955	COG1024	Enoyl-CoA hydratase
K1J60_RS08960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K1J60_RS08965	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS08970	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K1J60_RS08975	COG1250	3-hydroxyacyl-CoA dehydrogenase
K1J60_RS08990	COG0667	Aldo Keto reductase
K1J60_RS09005	COG0596	Alpha beta hydrolase
K1J60_RS09010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K1J60_RS09015	COG2080	2 iron, 2 sulfur cluster binding
K1J60_RS09020	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
K1J60_RS09025	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K1J60_RS09040	COG2272	Belongs to the type-B carboxylesterase lipase family
K1J60_RS09075	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS09115	COG2272	Belongs to the type-B carboxylesterase lipase family
K1J60_RS09145	COG4677	pectinesterase activity
K1J60_RS09160	COG3386	PFAM SMP-30 Gluconolaconase
K1J60_RS09185	COG1431	PFAM Stem cell self-renewal protein Piwi
K1J60_RS09200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K1J60_RS09210	COG1940	carbohydrate kinase activity
K1J60_RS09215	COG2188	Transcriptional regulator
K1J60_RS09220	COG0673	inositol 2-dehydrogenase activity
K1J60_RS09230	COG2197	response regulator
K1J60_RS09235	COG0667	Aldo Keto reductase
K1J60_RS09255	COG4266	Belongs to the allantoicase family
K1J60_RS09260	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K1J60_RS09265	COG1414	Transcriptional regulator
K1J60_RS09280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K1J60_RS09320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K1J60_RS09345	COG1733	regulation of RNA biosynthetic process
K1J60_RS09350	COG0436	Aminotransferase
K1J60_RS09360	COG0588	phosphoglycerate mutase activity
K1J60_RS09390	COG2351	hydroxyisourate hydrolase activity
K1J60_RS09410	COG3622	Belongs to the hyi family
K1J60_RS09415	COG2084	Dehydrogenase
K1J60_RS09420	COG3960	tartronate-semialdehyde synthase activity
K1J60_RS09430	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS09435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K1J60_RS09440	COG2197	response regulator
K1J60_RS09465	COG0745	RESPONSE REGULATOR receiver
K1J60_RS09485	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS09490	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS09525	COG1609	Transcriptional regulator
K1J60_RS09540	COG0725	ABC transporter, periplasmic molybdate-binding protein
K1J60_RS09560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K1J60_RS09565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K1J60_RS09570	COG0019	diaminopimelate decarboxylase activity
K1J60_RS09595	COG2890	protein-(glutamine-N5) methyltransferase activity
K1J60_RS09600	COG0517	IMP dehydrogenase activity
K1J60_RS09655	COG0596	Alpha beta hydrolase
K1J60_RS09660	COG0657	acetylesterase activity
K1J60_RS09695	COG0515	serine threonine protein kinase
K1J60_RS09730	COG0641	radical SAM
K1J60_RS09755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K1J60_RS09765	COG3962	Belongs to the TPP enzyme family
K1J60_RS09770	COG2188	Transcriptional regulator
K1J60_RS09780	COG1609	Transcriptional regulator
K1J60_RS09835	COG4249	Peptidase C14 caspase catalytic subunit p20
K1J60_RS09835	COG2319	Wd-40 repeat
K1J60_RS09845	COG2252	PERMEase
K1J60_RS09850	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K1J60_RS09865	COG3835	regulator
K1J60_RS09875	COG1802	Transcriptional regulator
K1J60_RS09910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K1J60_RS09920	COG1162	GTPase activity
K1J60_RS09945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K1J60_RS09950	COG0277	FAD linked oxidase domain protein
K1J60_RS09955	COG1940	carbohydrate kinase activity
K1J60_RS09965	COG1175	transmembrane transport
K1J60_RS09980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K1J60_RS10010	COG2755	lipolytic protein G-D-S-L family
K1J60_RS10045	COG0531	amino acid
K1J60_RS10050	COG2040	homocysteine
K1J60_RS10100	COG0395	ABC-type sugar transport system, permease component
K1J60_RS10105	COG1175	transmembrane transport
K1J60_RS10125	COG1175	transmembrane transport
K1J60_RS10130	COG0395	ABC-type sugar transport system, permease component
K1J60_RS10180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K1J60_RS10185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K1J60_RS10200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K1J60_RS10205	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS10235	COG0175	sulfate reduction
K1J60_RS10240	COG0529	Catalyzes the synthesis of activated sulfate
K1J60_RS10260	COG1116	anion transmembrane transporter activity
K1J60_RS10265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K1J60_RS10280	COG2409	Drug exporters of the RND superfamily
K1J60_RS10295	COG0675	Transposase, IS605 OrfB family
K1J60_RS10360	COG3173	Aminoglycoside phosphotransferase
K1J60_RS10370	COG1280	lysine exporter protein (LysE YggA)
K1J60_RS10375	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
K1J60_RS10390	COG0504	CTP synthase activity
K1J60_RS10410	COG1404	Belongs to the peptidase S8 family
K1J60_RS10500	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS10510	COG2018	Roadblock/LC7 domain
K1J60_RS10540	COG1609	Transcriptional regulator
K1J60_RS10560	COG0456	acetyltransferase
K1J60_RS10575	COG3629	intracellular signal transduction
K1J60_RS10575	COG3903	Transcriptional regulator
K1J60_RS10585	COG1335	isochorismatase
K1J60_RS10610	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K1J60_RS10615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K1J60_RS10650	COG0330	HflC and HflK could
K1J60_RS10680	COG0726	polysaccharide deacetylase
K1J60_RS10725	COG3220	belongs to the UPF0276 family
K1J60_RS10745	COG3253	May function as heme-dependent peroxidase
K1J60_RS10760	COG0446	pyridine nucleotide-disulphide oxidoreductase
K1J60_RS10775	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
K1J60_RS10790	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
K1J60_RS10795	COG3833	ABC-type maltose transport systems, permease component
K1J60_RS10800	COG1175	transmembrane transport
K1J60_RS10805	COG2182	Extracellular solute-binding protein
K1J60_RS10815	COG1609	Transcriptional regulator
K1J60_RS10820	COG0183	Belongs to the thiolase family
K1J60_RS10825	COG1250	3-hydroxyacyl-CoA dehydrogenase
K1J60_RS10825	COG1024	Enoyl-CoA hydratase
K1J60_RS10840	COG0531	amino acid
K1J60_RS10845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K1J60_RS10850	COG4214	carbohydrate transport
K1J60_RS10860	COG4213	ABC transporter substrate-binding protein
K1J60_RS10865	COG1940	carbohydrate kinase activity
K1J60_RS10870	COG0395	ABC-type sugar transport system, permease component
K1J60_RS10875	COG1175	transmembrane transport
K1J60_RS10880	COG1653	transport
K1J60_RS10910	COG1404	Belongs to the peptidase S8 family
K1J60_RS10920	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K1J60_RS10935	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K1J60_RS10945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K1J60_RS10950	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
K1J60_RS10980	COG2186	Transcriptional regulator
K1J60_RS11050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K1J60_RS11055	COG1401	restriction endodeoxyribonuclease activity
K1J60_RS11065	COG0210	DNA helicase
K1J60_RS11095	COG1653	transport
K1J60_RS11150	COG0288	reversible hydration of carbon dioxide
K1J60_RS11195	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS11200	COG0529	Catalyzes the synthesis of activated sulfate
K1J60_RS11220	COG1024	Enoyl-CoA hydratase
K1J60_RS11230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
K1J60_RS11250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K1J60_RS11255	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K1J60_RS11265	COG0737	Belongs to the 5'-nucleotidase family
K1J60_RS11270	COG1079	Belongs to the binding-protein-dependent transport system permease family
K1J60_RS11275	COG4603	Belongs to the binding-protein-dependent transport system permease family
K1J60_RS11280	COG3845	ABC transporter
K1J60_RS11285	COG1744	ABC transporter substrate-binding protein PnrA-like
K1J60_RS11290	COG0813	purine-nucleoside phosphorylase activity
K1J60_RS11300	COG1609	Transcriptional regulator
K1J60_RS11305	COG0402	S-adenosylhomocysteine deaminase activity
K1J60_RS11335	COG1799	cell septum assembly
K1J60_RS11340	COG0243	molybdopterin cofactor binding
K1J60_RS11405	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K1J60_RS11425	COG1132	(ABC) transporter
K1J60_RS11430	COG1132	(ABC) transporter
K1J60_RS11455	COG1120	ATPase activity
K1J60_RS11465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K1J60_RS11480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K1J60_RS11485	COG0531	amino acid
K1J60_RS11490	COG0569	domain protein
K1J60_RS11525	COG0756	dUTP diphosphatase activity
K1J60_RS11550	COG2205	protein histidine kinase activity
K1J60_RS11555	COG0745	RESPONSE REGULATOR receiver
K1J60_RS11570	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
K1J60_RS11600	COG1435	thymidine kinase activity
K1J60_RS11620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K1J60_RS11625	COG1802	Transcriptional regulator
K1J60_RS11640	COG0612	Peptidase, M16
K1J60_RS11645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K1J60_RS11670	COG3290	protein histidine kinase activity
K1J60_RS11675	COG4565	transcriptional regulatory protein
K1J60_RS11680	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K1J60_RS11690	COG0187	DNA topoisomerase II activity
K1J60_RS11705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K1J60_RS11710	COG2186	Transcriptional regulator
K1J60_RS11735	COG0514	ATP-dependent DNA helicase (RecQ)
K1J60_RS11750	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K1J60_RS11775	COG0588	phosphoglycerate mutase activity
K1J60_RS11790	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K1J60_RS11795	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K1J60_RS11800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K1J60_RS11840	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K1J60_RS11850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K1J60_RS11855	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
K1J60_RS11865	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K1J60_RS11885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K1J60_RS11915	COG3501	Rhs element vgr protein
K1J60_RS11945	COG2205	protein histidine kinase activity
K1J60_RS11950	COG0745	RESPONSE REGULATOR receiver
K1J60_RS11955	COG1126	abc transporter atp-binding protein
K1J60_RS11960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K1J60_RS11965	COG0765	amino acid transport
K1J60_RS11970	COG0765	amino acid transport
K1J60_RS11975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K1J60_RS11990	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K1J60_RS11995	COG0628	permease
K1J60_RS12025	COG1201	RNA secondary structure unwinding
K1J60_RS12030	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
K1J60_RS12035	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS12040	COG0783	Belongs to the Dps family
K1J60_RS12045	COG1396	sequence-specific DNA binding
K1J60_RS12050	COG1546	Belongs to the CinA family
K1J60_RS12050	COG1058	Belongs to the CinA family
K1J60_RS12060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K1J60_RS12070	COG1674	ftsk spoiiie
K1J60_RS12080	COG4999	Histidine kinase
K1J60_RS12080	COG3850	Histidine kinase
K1J60_RS12080	COG3437	response regulator, receiver
K1J60_RS12080	COG2205	protein histidine kinase activity
K1J60_RS12085	COG2770	Histidine kinase
K1J60_RS12085	COG2208	phosphoserine phosphatase activity
K1J60_RS12115	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K1J60_RS12120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K1J60_RS12125	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
K1J60_RS12140	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
K1J60_RS12145	COG0612	Peptidase, M16
K1J60_RS12150	COG1185	polyribonucleotide nucleotidyltransferase activity
K1J60_RS12155	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K1J60_RS12165	COG1674	ftsk spoiiie
K1J60_RS12180	COG1404	Belongs to the peptidase S8 family
K1J60_RS12245	COG0455	bacterial-type flagellum organization
K1J60_RS12260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K1J60_RS12265	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K1J60_RS12275	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
K1J60_RS12290	COG0779	Required for maturation of 30S ribosomal subunits
K1J60_RS12330	COG0442	prolyl-tRNA aminoacylation
K1J60_RS12345	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
K1J60_RS12350	COG0750	zinc metalloprotease
K1J60_RS12355	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
K1J60_RS12365	COG5297	Belongs to the glycosyl hydrolase family 6
K1J60_RS12380	COG0628	permease
K1J60_RS12390	COG3250	beta-galactosidase activity
K1J60_RS12400	COG1175	transmembrane transport
K1J60_RS12405	COG1653	transport
K1J60_RS12410	COG1609	Transcriptional regulator
K1J60_RS12435	COG0395	ABC-type sugar transport system, permease component
K1J60_RS12440	COG4209	transmembrane transport
K1J60_RS12450	COG1472	Belongs to the glycosyl hydrolase 3 family
K1J60_RS12455	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS12470	COG2508	Transcriptional regulator
K1J60_RS12495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K1J60_RS12500	COG1177	transmembrane transport
K1J60_RS12505	COG1176	ABC-type spermidine putrescine transport system, permease component I
K1J60_RS12510	COG3842	ATPase activity
K1J60_RS12535	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K1J60_RS12555	COG2353	YceI-like domain
K1J60_RS12560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K1J60_RS12565	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS12610	COG3842	ATPase activity
K1J60_RS12615	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
K1J60_RS12625	COG0820	rRNA (adenine-C2-)-methyltransferase activity
K1J60_RS12630	COG0575	Belongs to the CDS family
K1J60_RS12635	COG0233	cytoplasmic translational termination
K1J60_RS12640	COG0528	UMP kinase activity
K1J60_RS12645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
K1J60_RS12650	COG0052	Belongs to the universal ribosomal protein uS2 family
K1J60_RS12655	COG4942	peptidase
K1J60_RS12665	COG1191	sigma factor activity
K1J60_RS12680	COG0792	nuclease activity
K1J60_RS12690	COG0494	nUDIX hydrolase
K1J60_RS12695	COG0681	Belongs to the peptidase S26 family
K1J60_RS12700	COG0681	Belongs to the peptidase S26 family
K1J60_RS12710	COG0681	Belongs to the peptidase S26 family
K1J60_RS12715	COG0335	large ribosomal subunit rRNA binding
K1J60_RS12720	COG0336	Belongs to the RNA methyltransferase TrmD family
K1J60_RS12725	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K1J60_RS12730	COG1837	Belongs to the UPF0109 family
K1J60_RS12735	COG0228	four-way junction DNA binding
K1J60_RS12745	COG0442	prolyl-tRNA aminoacylation
K1J60_RS12760	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
K1J60_RS12795	COG0477	Major facilitator Superfamily
K1J60_RS12800	COG1196	nuclear chromosome segregation
K1J60_RS12810	COG1254	Belongs to the acylphosphatase family
K1J60_RS12815	COG2340	Cysteine-rich secretory protein family
K1J60_RS12820	COG1733	regulation of RNA biosynthetic process
K1J60_RS12825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
K1J60_RS12830	COG0571	ribonuclease III activity
K1J60_RS12835	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K1J60_RS12850	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
K1J60_RS12855	COG0742	ribosomal rna small subunit methyltransferase
K1J60_RS12865	COG0326	Molecular chaperone. Has ATPase activity
K1J60_RS12875	COG1461	Dihydroxyacetone kinase
K1J60_RS12880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
K1J60_RS12890	COG0351	phosphomethylpyrimidine kinase
K1J60_RS12910	COG1181	Belongs to the D-alanine--D-alanine ligase family
K1J60_RS12915	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K1J60_RS12925	COG1920	GTP binding
K1J60_RS12935	COG0776	regulation of translation
K1J60_RS12945	COG0066	3-isopropylmalate dehydratase activity
K1J60_RS12950	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K1J60_RS12955	COG1414	Transcriptional regulator
K1J60_RS12990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K1J60_RS12995	COG0179	Fumarylacetoacetate (FAA) hydrolase
K1J60_RS13005	COG5002	protein histidine kinase activity
K1J60_RS13010	COG2018	Roadblock/LC7 domain
K1J60_RS13030	COG2018	Roadblock/LC7 domain
K1J60_RS13050	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K1J60_RS13055	COG5492	domain, Protein
K1J60_RS13060	COG2353	YceI-like domain
K1J60_RS13090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K1J60_RS13095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K1J60_RS13100	COG0473	3-isopropylmalate dehydrogenase activity
K1J60_RS13110	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS13115	COG0506	proline dehydrogenase activity
K1J60_RS13120	COG2508	Transcriptional regulator
K1J60_RS13130	COG0747	negative chemotaxis
K1J60_RS13135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K1J60_RS13145	COG4608	Belongs to the ABC transporter superfamily
K1J60_RS13160	COG2197	response regulator
K1J60_RS13170	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K1J60_RS13175	COG0440	acetolactate synthase activity
K1J60_RS13185	COG5001	Diguanylate cyclase
K1J60_RS13195	COG0667	Aldo Keto reductase
K1J60_RS13200	COG2133	pyrroloquinoline quinone binding
K1J60_RS13210	COG2197	response regulator
K1J60_RS13225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K1J60_RS13230	COG2409	Drug exporters of the RND superfamily
K1J60_RS13235	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K1J60_RS13245	COG0154	amidase activity
K1J60_RS13250	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K1J60_RS13260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K1J60_RS13270	COG4221	oxidoreductase activity
K1J60_RS13285	COG0482	sulfurtransferase activity
K1J60_RS13290	COG3023	N-Acetylmuramoyl-L-alanine amidase
K1J60_RS13295	COG2132	Multicopper oxidase
K1J60_RS13315	COG1309	transcriptional regulator
K1J60_RS13330	COG2860	membrane
K1J60_RS13335	COG4608	Belongs to the ABC transporter superfamily
K1J60_RS13340	COG0444	Belongs to the ABC transporter superfamily
K1J60_RS13355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K1J60_RS13375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K1J60_RS13380	COG0509	glycine decarboxylation via glycine cleavage system
K1J60_RS13385	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K1J60_RS13390	COG1760	l-serine dehydratase
K1J60_RS13435	COG2259	Doxx family
K1J60_RS13455	COG0464	growth
K1J60_RS13550	COG2963	transposase activity
K1J60_RS13605	COG1132	(ABC) transporter
K1J60_RS13610	COG1132	(ABC) transporter
K1J60_RS13615	COG1132	(ABC) transporter
K1J60_RS13620	COG1132	(ABC) transporter
K1J60_RS13665	COG0058	SHG alpha-glucan phosphorylase activity
K1J60_RS13675	COG0366	Alpha amylase catalytic
K1J60_RS13680	COG0366	Alpha amylase catalytic
K1J60_RS13685	COG3281	Trehalose synthase
K1J60_RS13690	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K1J60_RS13705	COG3118	belongs to the thioredoxin family
K1J60_RS13705	COG0492	ferredoxin-NADP+ reductase activity
K1J60_RS13710	COG0789	Transcriptional regulator
K1J60_RS13715	COG1301	dicarboxylic acid transport
K1J60_RS13720	COG3290	protein histidine kinase activity
K1J60_RS13725	COG4565	transcriptional regulatory protein
K1J60_RS13740	COG1175	transmembrane transport
K1J60_RS13745	COG0395	ABC-type sugar transport system, permease component
K1J60_RS13755	COG3629	intracellular signal transduction
K1J60_RS13755	COG3903	Transcriptional regulator
K1J60_RS13770	COG0205	6-phosphofructokinase activity
K1J60_RS13775	COG0280	phosphate acetyltransferase
K1J60_RS13775	COG0857	belongs to the CobB CobQ family
K1J60_RS13780	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K1J60_RS13815	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K1J60_RS13815	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K1J60_RS13875	COG2205	protein histidine kinase activity
K1J60_RS13880	COG0745	RESPONSE REGULATOR receiver
K1J60_RS13900	COG0183	Belongs to the thiolase family
K1J60_RS13920	COG1131	(ABC) transporter
K1J60_RS13955	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
K1J60_RS13980	COG1250	3-hydroxyacyl-CoA dehydrogenase
K1J60_RS14005	COG4585	Histidine kinase
K1J60_RS14010	COG2197	response regulator
K1J60_RS14045	COG0355	proton-transporting ATP synthase activity, rotational mechanism
K1J60_RS14050	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K1J60_RS14055	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
K1J60_RS14060	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
K1J60_RS14065	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K1J60_RS14070	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K1J60_RS14075	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K1J60_RS14095	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K1J60_RS14100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K1J60_RS14110	COG2890	protein-(glutamine-N5) methyltransferase activity
K1J60_RS14115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
K1J60_RS14120	COG0254	rRNA binding
K1J60_RS14140	COG0083	homoserine kinase activity
K1J60_RS14145	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K1J60_RS14150	COG0460	homoserine dehydrogenase
K1J60_RS14155	COG0019	diaminopimelate decarboxylase activity
K1J60_RS14160	COG0018	arginyl-trna synthetase
K1J60_RS14225	COG3284	Transcriptional regulator
K1J60_RS14240	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
K1J60_RS14250	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K1J60_RS14255	COG3285	dna ligase
K1J60_RS14255	COG1793	dna ligase
K1J60_RS14275	COG2205	protein histidine kinase activity
K1J60_RS14290	COG0768	penicillin binding
K1J60_RS14360	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K1J60_RS14380	COG1309	transcriptional regulator
K1J60_RS14395	COG0745	RESPONSE REGULATOR receiver
K1J60_RS14400	COG2205	protein histidine kinase activity
K1J60_RS14405	COG0567	Dehydrogenase, E1 component
K1J60_RS14405	COG0508	dehydrogenase complex catalyzes the overall conversion of
K1J60_RS14440	COG0604	alcohol dehydrogenase
K1J60_RS14445	COG0281	malic enzyme
K1J60_RS14450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K1J60_RS14460	COG1126	abc transporter atp-binding protein
K1J60_RS14465	COG4106	trans-aconitate 2-methyltransferase activity
K1J60_RS14500	COG1609	Transcriptional regulator
K1J60_RS14510	COG1175	transmembrane transport
K1J60_RS14515	COG0395	ABC-type sugar transport system, permease component
K1J60_RS14520	COG4977	sequence-specific DNA binding
K1J60_RS14555	COG0142	geranyltranstransferase activity
K1J60_RS14560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K1J60_RS14600	COG1597	lipid kinase activity
K1J60_RS14615	COG0363	glucosamine-6-phosphate deaminase activity
K1J60_RS14620	COG1472	Belongs to the glycosyl hydrolase 3 family
K1J60_RS14625	COG0395	ABC-type sugar transport system, permease component
K1J60_RS14630	COG1175	transmembrane transport
K1J60_RS14635	COG2182	Extracellular solute-binding protein
K1J60_RS14640	COG2188	Transcriptional regulator
K1J60_RS14685	COG0242	peptide deformylase activity
K1J60_RS14725	COG5662	AntiSigma factor
K1J60_RS14730	COG1595	DNA-templated transcription, initiation
K1J60_RS14740	COG2135	peptidase activity
K1J60_RS14750	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
K1J60_RS14770	COG0483	inositol monophosphate 1-phosphatase activity
K1J60_RS14800	COG1615	UPF0182 protein
K1J60_RS14810	COG3480	Lon protease (S16) C-terminal proteolytic domain
K1J60_RS14865	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K1J60_RS14910	COG0210	DNA helicase
K1J60_RS14935	COG0596	Alpha beta hydrolase
K1J60_RS15010	COG1432	Conserved Protein
K1J60_RS15025	COG2095	MarC family integral membrane protein
K1J60_RS15030	COG0613	PHP domain protein
K1J60_RS15045	COG0598	Magnesium transport protein CorA
K1J60_RS15055	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
K1J60_RS15080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K1J60_RS15085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K1J60_RS15095	COG1595	DNA-templated transcription, initiation
K1J60_RS15110	COG1024	Enoyl-CoA hydratase
K1J60_RS15115	COG0519	Catalyzes the synthesis of GMP from XMP
K1J60_RS15125	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K1J60_RS15135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K1J60_RS15190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K1J60_RS15205	COG4608	Belongs to the ABC transporter superfamily
K1J60_RS15210	COG0444	Belongs to the ABC transporter superfamily
K1J60_RS15215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K1J60_RS15220	COG0601	transmembrane transport
K1J60_RS15230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K1J60_RS15235	COG4166	transmembrane transport
K1J60_RS15250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K1J60_RS15255	COG4608	Belongs to the ABC transporter superfamily
K1J60_RS15260	COG0444	Belongs to the ABC transporter superfamily
K1J60_RS15265	COG0601	transmembrane transport
K1J60_RS15270	COG0747	negative chemotaxis
K1J60_RS15275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K1J60_RS15280	COG1217	gtp-binding protein TYPA
K1J60_RS15300	COG1053	succinate dehydrogenase
K1J60_RS15305	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K1J60_RS15360	COG1192	Involved in chromosome partitioning
K1J60_RS15385	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS15405	COG0321	lipoyl(octanoyl) transferase activity
K1J60_RS15420	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS15435	COG0300	oxidoreductase activity
K1J60_RS15440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K1J60_RS15445	COG0596	Alpha beta hydrolase
K1J60_RS15465	COG0012	GTP binding
K1J60_RS15480	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K1J60_RS15485	COG1570	exodeoxyribonuclease VII activity
K1J60_RS15490	COG1722	exodeoxyribonuclease VII activity
K1J60_RS15515	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
K1J60_RS15515	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
K1J60_RS15520	COG0114	fumarate hydratase activity
K1J60_RS15525	COG3557	Belongs to the UPF0374 family
K1J60_RS15535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K1J60_RS15545	COG1136	(ABC) transporter
K1J60_RS15555	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K1J60_RS15565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K1J60_RS15570	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K1J60_RS15585	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K1J60_RS15595	COG2885	chlorophyll binding
K1J60_RS15645	COG2894	cell division
K1J60_RS15670	COG3209	COG3209 Rhs family protein
K1J60_RS15745	COG0251	oxidation-reduction process
K1J60_RS15750	COG1414	Transcriptional regulator
K1J60_RS15765	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
K1J60_RS15835	COG0515	serine threonine protein kinase
K1J60_RS15835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K1J60_RS15840	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
K1J60_RS15850	COG1309	transcriptional regulator
K1J60_RS15895	COG1331	Highly conserved protein containing a thioredoxin domain
K1J60_RS15910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K1J60_RS15920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K1J60_RS15935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K1J60_RS15940	COG2255	four-way junction helicase activity
K1J60_RS15945	COG1595	DNA-templated transcription, initiation
K1J60_RS15965	COG0501	Belongs to the peptidase M48B family
K1J60_RS15975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K1J60_RS15985	COG1064	alcohol dehydrogenase
K1J60_RS15995	COG1404	Belongs to the peptidase S8 family
K1J60_RS16000	COG1136	(ABC) transporter
K1J60_RS16010	COG1376	ErfK ybiS ycfS ynhG family protein
K1J60_RS16025	COG2986	histidine ammonia-lyase
K1J60_RS16035	COG1024	Enoyl-CoA hydratase
K1J60_RS16045	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
K1J60_RS16055	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K1J60_RS16065	COG0424	maF-like protein
K1J60_RS16075	COG4770	biotin carboxylase activity
K1J60_RS16085	COG1349	DNA-binding transcription factor activity
K1J60_RS16105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K1J60_RS16125	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS16130	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS16145	COG1595	DNA-templated transcription, initiation
K1J60_RS16150	COG0745	RESPONSE REGULATOR receiver
K1J60_RS16155	COG2205	protein histidine kinase activity
K1J60_RS16180	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K1J60_RS16190	COG0583	DNA-binding transcription factor activity
K1J60_RS16195	COG2814	Major facilitator Superfamily
K1J60_RS16225	COG1079	Belongs to the binding-protein-dependent transport system permease family
K1J60_RS16230	COG4603	Belongs to the binding-protein-dependent transport system permease family
K1J60_RS16235	COG3845	ABC transporter
K1J60_RS16240	COG1744	ABC transporter substrate-binding protein PnrA-like
K1J60_RS16245	COG1744	ABC transporter substrate-binding protein PnrA-like
K1J60_RS16250	COG1473	amidohydrolase
K1J60_RS16250	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
K1J60_RS16260	COG2089	acid synthase
K1J60_RS16275	COG1216	Glycosyl transferase, family 2
K1J60_RS16285	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
K1J60_RS16300	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K1J60_RS16300	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K1J60_RS16315	COG1595	DNA-templated transcription, initiation
K1J60_RS16325	COG1595	DNA-templated transcription, initiation
K1J60_RS16365	COG2009	succinate dehydrogenase
K1J60_RS16375	COG1053	succinate dehydrogenase
K1J60_RS16450	COG1309	transcriptional regulator
K1J60_RS16460	COG2409	Drug exporters of the RND superfamily
K1J60_RS16465	COG0745	RESPONSE REGULATOR receiver
K1J60_RS16470	COG2205	protein histidine kinase activity
K1J60_RS16485	COG1408	metallophosphoesterase
K1J60_RS16495	COG1686	Belongs to the peptidase S11 family
K1J60_RS16510	COG0671	phosphoesterase, PA-phosphatase related
K1J60_RS16530	COG0180	Tryptophanyl-tRNA synthetase
K1J60_RS16535	COG1595	DNA-templated transcription, initiation
K1J60_RS16550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K1J60_RS16555	COG0754	glutathionylspermidine amidase activity
K1J60_RS16570	COG0596	Alpha beta hydrolase
K1J60_RS16575	COG0456	acetyltransferase
K1J60_RS16575	COG1846	Transcriptional regulator
K1J60_RS16585	COG0039	L-malate dehydrogenase activity
K1J60_RS16610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K1J60_RS16635	COG0138	bifunctional purine biosynthesis protein purh
K1J60_RS16665	COG0045	succinate-CoA ligase (ADP-forming) activity
K1J60_RS16675	COG3552	Protein containing von Willebrand factor type A (VWA) domain
K1J60_RS16685	COG0714	Associated with various cellular activities
K1J60_RS16705	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K1J60_RS16715	COG0739	heme binding
K1J60_RS16735	COG0791	NLP P60 protein
K1J60_RS16740	COG2197	response regulator
K1J60_RS16780	COG0519	Catalyzes the synthesis of GMP from XMP
K1J60_RS16780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K1J60_RS16800	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS16805	COG0515	serine threonine protein kinase
K1J60_RS16840	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS16850	COG2815	serine threonine protein kinase
K1J60_RS16850	COG0515	serine threonine protein kinase
K1J60_RS16855	COG0515	serine threonine protein kinase
K1J60_RS16870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K1J60_RS16880	COG0516	GMP reductase activity
K1J60_RS16890	COG1595	DNA-templated transcription, initiation
K1J60_RS16905	COG0583	DNA-binding transcription factor activity
K1J60_RS16915	COG4221	oxidoreductase activity
K1J60_RS16925	COG0459	protein refolding
K1J60_RS16930	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K1J60_RS16935	COG0726	polysaccharide deacetylase
K1J60_RS16940	COG0726	polysaccharide deacetylase
K1J60_RS16950	COG4941	Belongs to the sigma-70 factor family
K1J60_RS16960	COG1316	TRANSCRIPTIONal
K1J60_RS16975	COG1653	transport
K1J60_RS16980	COG1175	transmembrane transport
K1J60_RS17015	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K1J60_RS17035	COG0802	atpase or kinase
K1J60_RS17045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K1J60_RS17050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K1J60_RS17055	COG0736	holo-[acyl-carrier-protein] synthase activity
K1J60_RS17085	COG1072	(Pantothenic acid kinase))
K1J60_RS17095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K1J60_RS17100	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K1J60_RS17105	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
K1J60_RS17115	COG0101	tRNA pseudouridine synthase activity
K1J60_RS17120	COG0203	ribosomal protein L17
K1J60_RS17125	COG0202	RNA polymerase activity
K1J60_RS17130	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
K1J60_RS17135	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K1J60_RS17140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K1J60_RS17145	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K1J60_RS17155	COG0563	adenylate kinase activity
K1J60_RS17165	COG0200	Binds to the 23S rRNA
K1J60_RS17170	COG1841	ribosomal large subunit assembly
K1J60_RS17175	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
K1J60_RS17180	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
K1J60_RS17185	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K1J60_RS17190	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
K1J60_RS17195	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
K1J60_RS17200	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K1J60_RS17205	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
K1J60_RS17210	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
K1J60_RS17215	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K1J60_RS17220	COG0255	Belongs to the universal ribosomal protein uL29 family
K1J60_RS17225	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
K1J60_RS17230	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
K1J60_RS17235	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K1J60_RS17240	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
K1J60_RS17245	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K1J60_RS17250	COG0089	rRNA binding
K1J60_RS17255	COG0088	Forms part of the polypeptide exit tunnel
K1J60_RS17260	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K1J60_RS17265	COG0051	transcription antitermination factor activity, RNA binding
K1J60_RS17290	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K1J60_RS17320	COG2319	Wd-40 repeat
K1J60_RS17320	COG4249	Peptidase C14 caspase catalytic subunit p20
K1J60_RS17360	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K1J60_RS17365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K1J60_RS17370	COG0049	tRNA binding
K1J60_RS17375	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K1J60_RS17410	COG0501	Belongs to the peptidase M48B family
K1J60_RS17415	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K1J60_RS17420	COG0085	RNA polymerase activity
K1J60_RS17425	COG0222	ribosome binding
K1J60_RS17430	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
K1J60_RS17445	COG0081	regulation of translation
K1J60_RS17470	COG0436	Aminotransferase
K1J60_RS17475	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K1J60_RS17480	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K1J60_RS17490	COG2030	dehydratase
K1J60_RS17495	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K1J60_RS17510	COG0402	S-adenosylhomocysteine deaminase activity
K1J60_RS17520	COG0702	epimerase
K1J60_RS17535	COG1666	GTP binding
K1J60_RS17540	COG2261	transglycosylase associated protein
K1J60_RS17550	COG3304	Inner membrane component domain
K1J60_RS17555	COG0501	Belongs to the peptidase M48B family
K1J60_RS17560	COG1007	ATP synthesis coupled electron transport
K1J60_RS17570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K1J60_RS17575	COG0713	ATP synthesis coupled electron transport
K1J60_RS17580	COG0839	Belongs to the complex I subunit 6 family
K1J60_RS17585	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K1J60_RS17590	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
K1J60_RS17595	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K1J60_RS17600	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K1J60_RS17605	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K1J60_RS17625	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K1J60_RS17625	COG0674	pyruvate-flavodoxin oxidoreductase activity
K1J60_RS17630	COG1013	pyruvate-flavodoxin oxidoreductase activity
K1J60_RS17635	COG1733	regulation of RNA biosynthetic process
K1J60_RS17640	COG0702	epimerase
K1J60_RS17670	COG0741	lytic transglycosylase activity
K1J60_RS17670	COG1196	nuclear chromosome segregation
K1J60_RS17670	COG0739	heme binding
K1J60_RS17720	COG0154	amidase activity
K1J60_RS17725	COG0655	NAD(P)H dehydrogenase (quinone) activity
K1J60_RS17745	COG0142	geranyltranstransferase activity
K1J60_RS17755	COG0561	phosphatase activity
K1J60_RS17785	COG0514	ATP-dependent DNA helicase (RecQ)
K1J60_RS17790	COG1007	ATP synthesis coupled electron transport
K1J60_RS17800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K1J60_RS17805	COG0713	ATP synthesis coupled electron transport
K1J60_RS17810	COG0839	Belongs to the complex I subunit 6 family
K1J60_RS17815	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K1J60_RS17820	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
K1J60_RS17825	COG1034	ATP synthesis coupled electron transport
K1J60_RS17830	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K1J60_RS17840	COG0649	NAD binding
K1J60_RS17845	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K1J60_RS17850	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K1J60_RS17860	COG0791	NLP P60 protein
K1J60_RS17885	COG2226	methyltransferase
K1J60_RS17900	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
K1J60_RS17915	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
K1J60_RS17920	COG1278	Cold shock
K1J60_RS17925	COG1396	sequence-specific DNA binding
K1J60_RS17965	COG1309	transcriptional regulator
K1J60_RS17980	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
K1J60_RS17990	COG0163	prenyltransferase activity
K1J60_RS18010	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
K1J60_RS18025	COG0789	Transcriptional regulator
K1J60_RS18090	COG1725	Transcriptional regulator
K1J60_RS18130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K1J60_RS18145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K1J60_RS18155	COG0406	alpha-ribazole phosphatase activity
K1J60_RS18160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
K1J60_RS18175	COG1476	TRANSCRIPTIONal
K1J60_RS18185	COG0477	Major facilitator Superfamily
K1J60_RS18190	COG0667	Aldo Keto reductase
K1J60_RS18205	COG0436	Aminotransferase
K1J60_RS18235	COG2205	protein histidine kinase activity
K1J60_RS18245	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS18255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K1J60_RS18275	COG1742	UPF0060 membrane protein
K1J60_RS18285	COG1690	Belongs to the RtcB family
K1J60_RS18305	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
K1J60_RS18310	COG0018	arginyl-trna synthetase
K1J60_RS18320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K1J60_RS18335	COG3152	Membrane
K1J60_RS18350	COG0113	porphobilinogen synthase activity
K1J60_RS18385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K1J60_RS18385	COG1648	precorrin-2 dehydrogenase activity
K1J60_RS18390	COG0181	hydroxymethylbilane synthase activity
K1J60_RS18395	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
K1J60_RS18400	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
K1J60_RS18450	COG0123	including yeast histone deacetylase and acetoin utilization protein
K1J60_RS18455	COG0738	Major facilitator superfamily
K1J60_RS18480	COG0180	Tryptophanyl-tRNA synthetase
K1J60_RS18485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K1J60_RS18495	COG0842	Transport permease protein
K1J60_RS18495	COG1129	ABC transporter
K1J60_RS18500	COG0659	secondary active sulfate transmembrane transporter activity
K1J60_RS18505	COG4106	trans-aconitate 2-methyltransferase activity
K1J60_RS18515	COG4991	sh3 domain protein
K1J60_RS18520	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K1J60_RS18520	COG0515	serine threonine protein kinase
K1J60_RS18525	COG0129	dihydroxy-acid dehydratase activity
K1J60_RS18530	COG1309	transcriptional regulator
K1J60_RS18535	COG1082	Xylose isomerase domain protein TIM barrel
K1J60_RS18540	COG0248	Ppx GppA phosphatase
K1J60_RS18565	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
K1J60_RS18580	COG1194	a g-specific adenine glycosylase
K1J60_RS18585	COG1595	DNA-templated transcription, initiation
K1J60_RS18595	COG0745	RESPONSE REGULATOR receiver
K1J60_RS18600	COG2205	protein histidine kinase activity
K1J60_RS18620	COG0739	heme binding
K1J60_RS18640	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K1J60_RS18660	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
K1J60_RS18670	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K1J60_RS18675	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
K1J60_RS18690	COG0640	Transcriptional regulator
K1J60_RS18695	COG2197	response regulator
K1J60_RS18710	COG0649	NAD binding
K1J60_RS18735	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K1J60_RS18735	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
K1J60_RS18750	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K1J60_RS18765	COG0302	gtp cyclohydrolase
K1J60_RS18780	COG0037	tRNA processing
K1J60_RS18790	COG2027	D-alanyl-D-alanine carboxypeptidase
K1J60_RS18795	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
K1J60_RS18810	COG0789	Transcriptional regulator
K1J60_RS18820	COG0076	glutamate decarboxylase activity
K1J60_RS18840	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS18860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
K1J60_RS18870	COG0254	rRNA binding
K1J60_RS18875	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K1J60_RS18880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
K1J60_RS18885	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
K1J60_RS18905	COG0577	efflux transmembrane transporter activity
K1J60_RS18905	COG1136	(ABC) transporter
K1J60_RS18920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K1J60_RS18920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K1J60_RS18930	COG3903	Transcriptional regulator
K1J60_RS18930	COG3629	intracellular signal transduction
K1J60_RS18975	COG4977	sequence-specific DNA binding
K1J60_RS18980	COG1653	transport
K1J60_RS18995	COG0515	serine threonine protein kinase
K1J60_RS19025	COG0745	RESPONSE REGULATOR receiver
K1J60_RS19030	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS19035	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS19050	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
K1J60_RS19055	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K1J60_RS19065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K1J60_RS19065	COG0519	Catalyzes the synthesis of GMP from XMP
K1J60_RS19070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K1J60_RS19075	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS19090	COG0789	Transcriptional regulator
K1J60_RS19110	COG0470	DNA polymerase III
K1J60_RS19115	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K1J60_RS19120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K1J60_RS19120	COG1754	DNA topoisomerase type I activity
K1J60_RS19130	COG2815	serine threonine protein kinase
K1J60_RS19130	COG0515	serine threonine protein kinase
K1J60_RS19145	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
K1J60_RS19150	COG2172	sigma factor antagonist activity
K1J60_RS19155	COG1366	Belongs to the anti-sigma-factor antagonist family
K1J60_RS19160	COG1205	dead DEAH box helicase
K1J60_RS19160	COG1111	helicase
K1J60_RS19225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K1J60_RS19230	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K1J60_RS19240	COG2267	carboxylic ester hydrolase activity
K1J60_RS19265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K1J60_RS19275	COG0251	oxidation-reduction process
K1J60_RS19290	COG0003	Pfam Anion-transporting ATPase
K1J60_RS19310	COG1408	metallophosphoesterase
K1J60_RS19345	COG1609	Transcriptional regulator
K1J60_RS19350	COG3328	transposase activity
K1J60_RS19365	COG0583	DNA-binding transcription factor activity
K1J60_RS19390	COG3903	Transcriptional regulator
K1J60_RS19390	COG3629	intracellular signal transduction
K1J60_RS19410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K1J60_RS19420	COG2124	cytochrome p450
K1J60_RS19440	COG4249	Peptidase C14 caspase catalytic subunit p20
K1J60_RS19440	COG2319	Wd-40 repeat
K1J60_RS19450	COG0701	Predicted permease
K1J60_RS19500	COG1595	DNA-templated transcription, initiation
K1J60_RS19520	COG5002	protein histidine kinase activity
K1J60_RS19545	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K1J60_RS19550	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
K1J60_RS19570	COG0693	protein deglycase activity
K1J60_RS19580	COG1802	Transcriptional regulator
K1J60_RS19605	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K1J60_RS19655	COG1131	(ABC) transporter
K1J60_RS19660	COG3559	Exporter of polyketide antibiotics
K1J60_RS19670	COG2197	response regulator
K1J60_RS19675	COG4585	Histidine kinase
K1J60_RS19690	COG3483	tryptophan 2,3-dioxygenase activity
K1J60_RS19700	COG0477	Major facilitator Superfamily
K1J60_RS19710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
K1J60_RS19725	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
K1J60_RS19775	COG0604	alcohol dehydrogenase
K1J60_RS19800	COG0542	response to heat
K1J60_RS19840	COG2308	Evidence 4 Homologs of previously reported genes of
K1J60_RS19850	COG1305	Transglutaminase-like
K1J60_RS19855	COG4213	ABC transporter substrate-binding protein
K1J60_RS19975	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K1J60_RS20015	COG0501	Belongs to the peptidase M48B family
K1J60_RS20060	COG5297	Belongs to the glycosyl hydrolase family 6
K1J60_RS20060	COG4733	cellulase activity
K1J60_RS20065	COG0789	Transcriptional regulator
K1J60_RS20070	COG0484	heat shock protein binding
K1J60_RS20075	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K1J60_RS20080	COG0443	Heat shock 70 kDa protein
K1J60_RS20085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K1J60_RS20090	COG0247	lactate metabolic process
K1J60_RS20090	COG2181	nitrate reductase activity
K1J60_RS20155	COG0717	Belongs to the dCTP deaminase family
K1J60_RS20170	COG3290	protein histidine kinase activity
K1J60_RS20220	COG3119	arylsulfatase activity
K1J60_RS20225	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K1J60_RS20250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K1J60_RS20260	COG0477	Major facilitator Superfamily
K1J60_RS20270	COG2824	Alkylphosphonate utilization operon protein PhnA
K1J60_RS20290	COG0659	secondary active sulfate transmembrane transporter activity
K1J60_RS20335	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
K1J60_RS20340	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
K1J60_RS20345	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
K1J60_RS20395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K1J60_RS20445	COG1302	Protein conserved in bacteria
K1J60_RS20485	COG1278	Cold shock
K1J60_RS20490	COG0513	Belongs to the DEAD box helicase family
K1J60_RS20515	COG0640	Transcriptional regulator
K1J60_RS20520	COG1902	pentaerythritol trinitrate reductase activity
K1J60_RS20525	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS20530	COG1064	alcohol dehydrogenase
K1J60_RS20605	COG0515	serine threonine protein kinase
K1J60_RS20605	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K1J60_RS20615	COG0641	radical SAM
K1J60_RS20695	COG0726	polysaccharide deacetylase
K1J60_RS20710	COG0702	epimerase
K1J60_RS20715	COG4213	ABC transporter substrate-binding protein
K1J60_RS20725	COG4214	carbohydrate transport
K1J60_RS20730	COG1309	transcriptional regulator
K1J60_RS20740	COG2072	flavoprotein involved in K transport
K1J60_RS20765	COG0662	Cupin 2, conserved barrel domain protein
K1J60_RS20780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K1J60_RS20805	COG1295	ribonuclease BN
K1J60_RS20825	COG0531	amino acid
K1J60_RS20840	COG1278	Cold shock
K1J60_RS20845	COG0513	Belongs to the DEAD box helicase family
K1J60_RS20855	COG0640	Transcriptional regulator
K1J60_RS20870	COG2197	response regulator
K1J60_RS20895	COG2764	glyoxalase bleomycin resistance protein dioxygenase
K1J60_RS20905	COG4941	Belongs to the sigma-70 factor family
K1J60_RS20910	COG3795	YCII-related domain
K1J60_RS20920	COG3973	AAA domain
K1J60_RS20950	COG2318	DinB family
K1J60_RS20975	COG0596	Alpha beta hydrolase
K1J60_RS21000	COG1609	Transcriptional regulator
K1J60_RS21010	COG4585	Histidine kinase
K1J60_RS21015	COG2197	response regulator
K1J60_RS21040	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K1J60_RS21075	COG4585	Histidine kinase
K1J60_RS21115	COG1309	transcriptional regulator
K1J60_RS21135	COG0137	argininosuccinate synthase activity
K1J60_RS21160	COG2176	DNA-directed DNA polymerase activity
K1J60_RS21185	COG1733	regulation of RNA biosynthetic process
K1J60_RS21195	COG3345	alpha-galactosidase
K1J60_RS21225	COG0789	Transcriptional regulator
K1J60_RS21230	COG4221	oxidoreductase activity
K1J60_RS21305	COG1595	DNA-templated transcription, initiation
K1J60_RS21325	COG2319	Wd-40 repeat
K1J60_RS21325	COG4249	Peptidase C14 caspase catalytic subunit p20
K1J60_RS21345	COG0745	RESPONSE REGULATOR receiver
K1J60_RS21350	COG2205	protein histidine kinase activity
K1J60_RS21380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K1J60_RS21385	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K1J60_RS21400	COG1289	transmembrane transporter activity
K1J60_RS21420	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K1J60_RS21435	COG3866	Pectate lyase
K1J60_RS21445	COG2340	Cysteine-rich secretory protein family
K1J60_RS21505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
K1J60_RS21525	COG1741	Belongs to the pirin family
K1J60_RS21535	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS21540	COG1362	aminopeptidase activity
K1J60_RS21610	COG0508	dehydrogenase complex catalyzes the overall conversion of
K1J60_RS21615	COG0022	dehydrogenase e1 component
K1J60_RS21630	COG0515	serine threonine protein kinase
K1J60_RS21635	COG0515	serine threonine protein kinase
K1J60_RS21650	COG3321	synthase
K1J60_RS21650	COG0604	alcohol dehydrogenase
K1J60_RS21650	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS21665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K1J60_RS21675	COG0746	molybdenum cofactor guanylyltransferase activity
K1J60_RS21695	COG1522	sequence-specific DNA binding
K1J60_RS21700	COG1309	transcriptional regulator
K1J60_RS21705	COG1250	3-hydroxyacyl-CoA dehydrogenase
K1J60_RS21730	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS21765	COG1716	ATPase activity
K1J60_RS21770	COG1716	ATPase activity
K1J60_RS21790	COG0515	serine threonine protein kinase
K1J60_RS21795	COG3764	Sortase (surface protein transpeptidase)
K1J60_RS21800	COG3764	Sortase (surface protein transpeptidase)
K1J60_RS21815	COG3764	Sortase (surface protein transpeptidase)
K1J60_RS21830	COG0705	Rhomboid family
K1J60_RS21855	COG0515	serine threonine protein kinase
K1J60_RS21885	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K1J60_RS21890	COG0187	DNA topoisomerase II activity
K1J60_RS21895	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
K1J60_RS21900	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K1J60_RS21905	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K1J60_RS21910	COG0592	DNA-directed DNA polymerase activity
K1J60_RS21915	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K1J60_RS21925	COG0594	ribonuclease P activity
K1J60_RS21930	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
K1J60_RS21935	COG0706	membrane insertase activity
K1J60_RS21945	COG0357	Ribosomal RNA small subunit methyltransferase G
K1J60_RS21950	COG1192	Involved in chromosome partitioning
K1J60_RS21965	COG3118	belongs to the thioredoxin family
K1J60_RS21970	COG0492	ferredoxin-NADP+ reductase activity
K1J60_RS21980	COG1595	DNA-templated transcription, initiation
K1J60_RS21985	COG0515	serine threonine protein kinase
K1J60_RS21985	COG2815	serine threonine protein kinase
K1J60_RS22000	COG0617	tRNA 3'-terminal CCA addition
K1J60_RS22020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K1J60_RS22045	COG0360	Binds together with S18 to 16S ribosomal RNA
K1J60_RS22050	COG0629	single-stranded DNA binding
K1J60_RS22055	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
K1J60_RS22060	COG0359	binds to the 23S rRNA
K1J60_RS22070	COG0305	Participates in initiation and elongation during chromosome replication
K1J60_RS22115	COG0626	cystathionine gamma-synthase activity
K1J60_RS22120	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K1J60_RS22125	COG1950	PFAM Membrane protein of
K1J60_RS22130	COG0662	Cupin 2, conserved barrel domain protein
K1J60_RS22155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
K1J60_RS22170	COG1609	Transcriptional regulator
K1J60_RS22175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K1J60_RS22180	COG1271	oxidase subunit
K1J60_RS22185	COG1294	oxidase, subunit
K1J60_RS22190	COG4988	ABC transporter
K1J60_RS22195	COG1196	nuclear chromosome segregation
K1J60_RS22195	COG0741	lytic transglycosylase activity
K1J60_RS22195	COG0739	heme binding
K1J60_RS22200	COG0561	phosphatase activity
K1J60_RS22210	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
K1J60_RS22215	COG0789	Transcriptional regulator
K1J60_RS22225	COG1131	(ABC) transporter
K1J60_RS22255	COG0561	phosphatase activity
K1J60_RS22260	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K1J60_RS22265	COG0077	Prephenate dehydratase
K1J60_RS22270	COG2837	iron assimilation
K1J60_RS22285	COG1999	signal sequence binding
K1J60_RS22315	COG0641	radical SAM
K1J60_RS22330	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
K1J60_RS22335	COG0006	proline dipeptidase activity
K1J60_RS22355	COG0653	protein targeting
K1J60_RS22370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K1J60_RS22390	COG2801	Transposase and inactivated derivatives
K1J60_RS22440	COG1595	DNA-templated transcription, initiation
K1J60_RS22445	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS22450	COG0784	Response regulator, receiver
K1J60_RS22480	COG0745	RESPONSE REGULATOR receiver
K1J60_RS22485	COG2205	protein histidine kinase activity
K1J60_RS22495	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
K1J60_RS22495	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
K1J60_RS22500	COG0477	Major facilitator Superfamily
K1J60_RS22510	COG3467	pyridoxamine 5'-phosphate
K1J60_RS22515	COG2353	YceI-like domain
K1J60_RS22520	COG0477	Major facilitator Superfamily
K1J60_RS22535	COG1191	sigma factor activity
K1J60_RS22540	COG1191	sigma factor activity
K1J60_RS22575	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K1J60_RS22620	COG1276	copper resistance
K1J60_RS22620	COG2372	response to copper ion
K1J60_RS22655	COG4977	sequence-specific DNA binding
K1J60_RS22690	COG2018	Roadblock/LC7 domain
K1J60_RS22745	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K1J60_RS22820	COG0305	Participates in initiation and elongation during chromosome replication
K1J60_RS22875	COG0151	Belongs to the GarS family
K1J60_RS22890	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
K1J60_RS22900	COG2197	response regulator
K1J60_RS22935	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K1J60_RS22940	COG0047	phosphoribosylformylglycinamidine synthase activity
K1J60_RS22945	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K1J60_RS22970	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
K1J60_RS23005	COG1643	Atp-dependent helicase
K1J60_RS23040	COG0513	Belongs to the DEAD box helicase family
K1J60_RS23140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K1J60_RS23155	COG0717	Belongs to the dCTP deaminase family
K1J60_RS23160	COG0297	glycogen (starch) synthase activity
K1J60_RS23165	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K1J60_RS23185	COG1857	crispr-associated protein
K1J60_RS23280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K1J60_RS23280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K1J60_RS23290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K1J60_RS23305	COG1335	isochorismatase
K1J60_RS23315	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K1J60_RS23320	COG0579	oxidoreductase
K1J60_RS23350	COG1252	NADH dehydrogenase
K1J60_RS23365	COG1846	Transcriptional regulator
K1J60_RS23435	COG0539	negative regulation of cytoplasmic translation
K1J60_RS23460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K1J60_RS23485	COG1196	nuclear chromosome segregation
K1J60_RS23485	COG0741	lytic transglycosylase activity
K1J60_RS23485	COG0739	heme binding
K1J60_RS23490	COG0671	phosphoesterase, PA-phosphatase related
K1J60_RS23495	COG0277	FAD linked oxidase domain protein
K1J60_RS23515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K1J60_RS23520	COG0306	phosphate transporter
K1J60_RS23530	COG1937	Protein conserved in bacteria
K1J60_RS23550	COG0406	alpha-ribazole phosphatase activity
K1J60_RS23550	COG0494	nUDIX hydrolase
K1J60_RS23560	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K1J60_RS23575	COG1131	(ABC) transporter
K1J60_RS23580	COG1725	Transcriptional regulator
K1J60_RS23585	COG0456	acetyltransferase
K1J60_RS23590	COG0737	Belongs to the 5'-nucleotidase family
K1J60_RS23640	COG0745	RESPONSE REGULATOR receiver
K1J60_RS23650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K1J60_RS23655	COG1609	Transcriptional regulator
K1J60_RS23660	COG0745	RESPONSE REGULATOR receiver
K1J60_RS23685	COG2897	thiosulfate sulfurtransferase activity
K1J60_RS23720	COG3485	protocatechuate 3,4-dioxygenase
K1J60_RS23725	COG0735	belongs to the Fur family
K1J60_RS23735	COG1490	D-aminoacyl-tRNA deacylase activity
K1J60_RS23745	COG4552	Acetyltransferase involved in intracellular survival and related
K1J60_RS23750	COG2188	Transcriptional regulator
K1J60_RS23760	COG2188	Transcriptional regulator
K1J60_RS23780	COG0546	phosphoglycolate phosphatase activity
K1J60_RS23790	COG1309	transcriptional regulator
K1J60_RS23795	COG3973	AAA domain
K1J60_RS23805	COG2318	DinB family
K1J60_RS23875	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS23885	COG1917	Cupin 2, conserved barrel domain protein
K1J60_RS23885	COG2207	Transcriptional regulator
K1J60_RS23900	COG0588	phosphoglycerate mutase activity
K1J60_RS23905	COG4974	Belongs to the 'phage' integrase family
K1J60_RS23955	COG2188	Transcriptional regulator
K1J60_RS24030	COG1329	Transcriptional regulator
K1J60_RS24035	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
K1J60_RS24040	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
K1J60_RS24045	COG0215	cysteine-tRNA ligase activity
K1J60_RS24070	COG3842	ATPase activity
K1J60_RS24105	COG2801	Transposase and inactivated derivatives
K1J60_RS24170	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
K1J60_RS24205	COG2182	Extracellular solute-binding protein
K1J60_RS24225	COG0463	Glycosyl transferase, family 2
K1J60_RS24240	COG1278	Cold shock
K1J60_RS24245	COG0459	protein refolding
K1J60_RS24270	COG2318	DinB family
K1J60_RS24300	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
K1J60_RS24305	COG1737	Transcriptional regulator
K1J60_RS24375	COG3973	AAA domain
K1J60_RS24390	COG1061	Type III restriction enzyme res subunit
K1J60_RS24430	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
K1J60_RS24435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K1J60_RS24445	COG2814	Major facilitator Superfamily
K1J60_RS24470	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K1J60_RS24480	COG2252	PERMEase
K1J60_RS24505	COG0667	Aldo Keto reductase
K1J60_RS24550	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
K1J60_RS24560	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
K1J60_RS24585	COG0277	FAD linked oxidase domain protein
K1J60_RS24585	COG0247	lactate metabolic process
K1J60_RS24620	COG5006	permease, DMT superfamily
K1J60_RS24635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K1J60_RS24650	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS24665	COG0259	pyridoxamine-phosphate oxidase activity
K1J60_RS24690	COG4821	SIS domain
K1J60_RS24700	COG2945	thiolester hydrolase activity
K1J60_RS24700	COG0596	Alpha beta hydrolase
K1J60_RS24755	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS24765	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS24770	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS24785	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS24790	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS24810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K1J60_RS24815	COG1024	Enoyl-CoA hydratase
K1J60_RS24825	COG2072	flavoprotein involved in K transport
K1J60_RS24855	COG0259	pyridoxamine-phosphate oxidase activity
K1J60_RS24870	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS24890	COG0515	serine threonine protein kinase
K1J60_RS24890	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K1J60_RS24895	COG1404	Belongs to the peptidase S8 family
K1J60_RS24905	COG0745	RESPONSE REGULATOR receiver
K1J60_RS24910	COG5002	protein histidine kinase activity
K1J60_RS24930	COG1024	Enoyl-CoA hydratase
K1J60_RS24960	COG3903	Transcriptional regulator
K1J60_RS24960	COG3629	intracellular signal transduction
K1J60_RS24975	COG1131	(ABC) transporter
K1J60_RS24995	COG1131	(ABC) transporter
K1J60_RS25005	COG2197	response regulator
K1J60_RS25050	COG2226	methyltransferase
K1J60_RS25095	COG1116	anion transmembrane transporter activity
K1J60_RS25120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K1J60_RS25135	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
K1J60_RS25165	COG3896	Chloramphenicol phosphotransferase-like protein
K1J60_RS25200	COG1686	Belongs to the peptidase S11 family
K1J60_RS25215	COG0386	Belongs to the glutathione peroxidase family
K1J60_RS25275	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K1J60_RS25305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K1J60_RS25385	COG0604	alcohol dehydrogenase
K1J60_RS25415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K1J60_RS25420	COG3485	protocatechuate 3,4-dioxygenase
K1J60_RS25435	COG3152	Membrane
K1J60_RS25475	COG0583	DNA-binding transcription factor activity
K1J60_RS25480	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS25485	COG4555	ABC transporter
K1J60_RS25505	COG1414	Transcriptional regulator
K1J60_RS25525	COG1846	Transcriptional regulator
K1J60_RS25530	COG3384	dioxygenase
K1J60_RS25540	COG1247	-acetyltransferase
K1J60_RS25555	COG0477	Major facilitator Superfamily
K1J60_RS25585	COG1376	ErfK ybiS ycfS ynhG family protein
K1J60_RS25605	COG1970	mechanosensitive ion channel activity
K1J60_RS25615	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
K1J60_RS25640	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K1J60_RS25645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K1J60_RS25655	COG0315	cyclic pyranopterin monophosphate synthase activity
K1J60_RS25660	COG0521	Mo-molybdopterin cofactor biosynthetic process
K1J60_RS25660	COG0315	cyclic pyranopterin monophosphate synthase activity
K1J60_RS25665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K1J60_RS25690	COG0708	Exodeoxyribonuclease III
K1J60_RS25705	COG2072	flavoprotein involved in K transport
K1J60_RS25710	COG2267	carboxylic ester hydrolase activity
K1J60_RS25725	COG1733	regulation of RNA biosynthetic process
K1J60_RS25730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K1J60_RS25735	COG0793	Belongs to the peptidase S41A family
K1J60_RS25735	COG4946	Tricorn protease homolog
K1J60_RS25745	COG2409	Drug exporters of the RND superfamily
K1J60_RS25750	COG2318	DinB family
K1J60_RS25780	COG0310	cobalt ion transport
K1J60_RS25790	COG1122	ATPase activity
K1J60_RS25795	COG1846	Transcriptional regulator
K1J60_RS25800	COG1764	response to oxidative stress
K1J60_RS25835	COG0442	prolyl-tRNA aminoacylation
K1J60_RS25850	COG0768	penicillin binding
K1J60_RS25870	COG0084	hydrolase, TatD family'
K1J60_RS25880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K1J60_RS25885	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
K1J60_RS25905	COG0488	(ABC) transporter
K1J60_RS25955	COG1725	Transcriptional regulator
K1J60_RS25960	COG1131	(ABC) transporter
K1J60_RS25970	COG1404	Belongs to the peptidase S8 family
K1J60_RS25985	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
K1J60_RS26005	COG2197	response regulator
K1J60_RS26015	COG4106	trans-aconitate 2-methyltransferase activity
K1J60_RS26025	COG0477	Major facilitator Superfamily
K1J60_RS26035	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS26040	COG1309	transcriptional regulator
K1J60_RS26050	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
K1J60_RS26060	COG0193	aminoacyl-tRNA hydrolase activity
K1J60_RS26065	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K1J60_RS26070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K1J60_RS26075	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K1J60_RS26120	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K1J60_RS26145	COG2814	Major facilitator Superfamily
K1J60_RS26150	COG1136	(ABC) transporter
K1J60_RS26155	COG0577	efflux transmembrane transporter activity
K1J60_RS26230	COG0148	phosphopyruvate hydratase activity
K1J60_RS26250	COG1252	NADH dehydrogenase
K1J60_RS26255	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K1J60_RS26260	COG0577	efflux transmembrane transporter activity
K1J60_RS26265	COG0577	efflux transmembrane transporter activity
K1J60_RS26265	COG1136	(ABC) transporter
K1J60_RS26295	COG0183	Belongs to the thiolase family
K1J60_RS26300	COG2755	lipolytic protein G-D-S-L family
K1J60_RS26330	COG2192	nodulation
K1J60_RS26350	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
K1J60_RS26365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K1J60_RS26375	COG0626	cystathionine gamma-synthase activity
K1J60_RS26380	COG0646	methionine synthase
K1J60_RS26380	COG1410	methionine synthase
K1J60_RS26395	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS26400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
K1J60_RS26415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K1J60_RS26420	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K1J60_RS26425	COG0066	3-isopropylmalate dehydratase activity
K1J60_RS26450	COG1522	sequence-specific DNA binding
K1J60_RS26460	COG2986	histidine ammonia-lyase
K1J60_RS26510	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
K1J60_RS26515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K1J60_RS26525	COG1228	amidohydrolase
K1J60_RS26535	COG1191	sigma factor activity
K1J60_RS26540	COG1366	Belongs to the anti-sigma-factor antagonist family
K1J60_RS26560	COG3104	oligopeptide transport
K1J60_RS26565	COG0745	RESPONSE REGULATOR receiver
K1J60_RS26570	COG2205	protein histidine kinase activity
K1J60_RS26585	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K1J60_RS26610	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K1J60_RS26625	COG1316	TRANSCRIPTIONal
K1J60_RS26630	COG1316	TRANSCRIPTIONal
K1J60_RS26635	COG0463	Glycosyl transferase, family 2
K1J60_RS26645	COG1316	TRANSCRIPTIONal
K1J60_RS26650	COG1316	TRANSCRIPTIONal
K1J60_RS26665	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K1J60_RS26675	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
K1J60_RS26675	COG0778	Nitroreductase
K1J60_RS26680	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K1J60_RS26715	COG1620	l-lactate permease
K1J60_RS26725	COG2835	tetraacyldisaccharide 4'-kinase activity
K1J60_RS26745	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
K1J60_RS26785	COG0714	Associated with various cellular activities
K1J60_RS26805	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
K1J60_RS26810	COG0745	RESPONSE REGULATOR receiver
K1J60_RS26815	COG5000	phosphorelay sensor kinase activity
K1J60_RS26815	COG5002	protein histidine kinase activity
K1J60_RS26820	COG0823	Involved in the tonB-independent uptake of proteins
K1J60_RS26830	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K1J60_RS26835	COG2197	response regulator
K1J60_RS26840	COG3214	Protein conserved in bacteria
K1J60_RS26850	COG0653	protein targeting
K1J60_RS26875	COG2902	Dehydrogenase
K1J60_RS26890	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K1J60_RS26890	COG0463	Glycosyl transferase, family 2
K1J60_RS26895	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS26900	COG1134	teichoic acid transport
K1J60_RS26950	COG1215	transferase activity, transferring glycosyl groups
K1J60_RS26955	COG1846	Transcriptional regulator
K1J60_RS26960	COG1764	response to oxidative stress
K1J60_RS26975	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K1J60_RS26980	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K1J60_RS26985	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K1J60_RS26985	COG0463	Glycosyl transferase, family 2
K1J60_RS26990	COG0395	ABC-type sugar transport system, permease component
K1J60_RS26995	COG1175	transmembrane transport
K1J60_RS27000	COG1653	transport
K1J60_RS27010	COG0515	serine threonine protein kinase
K1J60_RS27015	COG0515	serine threonine protein kinase
K1J60_RS27020	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
K1J60_RS27035	COG2884	Cell division ATP-binding protein ftsE
K1J60_RS27040	COG2177	Part of the ABC transporter FtsEX involved in
K1J60_RS27045	COG0793	Belongs to the peptidase S41A family
K1J60_RS27050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
K1J60_RS27065	COG1501	Belongs to the glycosyl hydrolase 31 family
K1J60_RS27070	COG0395	ABC-type sugar transport system, permease component
K1J60_RS27075	COG1175	transmembrane transport
K1J60_RS27090	COG0583	DNA-binding transcription factor activity
K1J60_RS27125	COG2223	nitrite transmembrane transporter activity
K1J60_RS27150	COG3973	AAA domain
K1J60_RS27160	COG0776	regulation of translation
K1J60_RS27165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K1J60_RS27170	COG1678	Uncharacterized ACR, COG1678
K1J60_RS27185	COG1175	transmembrane transport
K1J60_RS27190	COG0395	ABC-type sugar transport system, permease component
K1J60_RS27195	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K1J60_RS27210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K1J60_RS27240	COG3654	unkown
K1J60_RS27275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
K1J60_RS27285	COG0277	FAD linked oxidase domain protein
K1J60_RS27320	COG1335	isochorismatase
K1J60_RS27330	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
K1J60_RS27340	COG1113	amino acid transport
K1J60_RS27365	COG1234	tRNA 3'-trailer cleavage
K1J60_RS27370	COG1263	PTS System
K1J60_RS27375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K1J60_RS27380	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K1J60_RS27390	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
K1J60_RS27430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K1J60_RS27460	COG2733	membrane
K1J60_RS27495	COG2271	Major facilitator Superfamily
K1J60_RS27570	COG3764	Sortase (surface protein transpeptidase)
K1J60_RS27580	COG0706	membrane insertase activity
K1J60_RS27590	COG4702	Belongs to the UPF0303 family
K1J60_RS27595	COG0673	inositol 2-dehydrogenase activity
K1J60_RS27680	COG3397	chitin binding
K1J60_RS27690	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS27700	COG2197	response regulator
K1J60_RS27715	COG1126	abc transporter atp-binding protein
K1J60_RS27720	COG0765	amino acid transport
K1J60_RS27725	COG0765	amino acid transport
K1J60_RS27730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K1J60_RS27750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K1J60_RS27765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K1J60_RS27815	COG0588	phosphoglycerate mutase activity
K1J60_RS27840	COG0745	RESPONSE REGULATOR receiver
K1J60_RS27845	COG2205	protein histidine kinase activity
K1J60_RS27865	COG3842	ATPase activity
K1J60_RS27870	COG1653	transport
K1J60_RS27875	COG1175	transmembrane transport
K1J60_RS27880	COG0395	ABC-type sugar transport system, permease component
K1J60_RS27885	COG3345	alpha-galactosidase
K1J60_RS27920	COG1175	transmembrane transport
K1J60_RS27965	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
K1J60_RS27970	COG4977	sequence-specific DNA binding
K1J60_RS27980	COG0589	response to stress
K1J60_RS27985	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K1J60_RS28015	COG3486	L-lysine 6-monooxygenase (NADPH) activity
K1J60_RS28035	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS28050	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K1J60_RS28055	COG1309	transcriptional regulator
K1J60_RS28065	COG1946	Acyl-CoA thioesterase
K1J60_RS28085	COG0028	Belongs to the TPP enzyme family
K1J60_RS28100	COG2356	endonuclease I
K1J60_RS28145	COG0189	ligase activity
K1J60_RS28160	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K1J60_RS28165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K1J60_RS28175	COG3958	Transketolase
K1J60_RS28215	COG1472	Belongs to the glycosyl hydrolase 3 family
K1J60_RS28220	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
K1J60_RS28225	COG3340	Belongs to the peptidase S51 family
K1J60_RS28230	COG0110	maltose O-acetyltransferase activity
K1J60_RS28245	COG0723	plastoquinol--plastocyanin reductase activity
K1J60_RS28245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K1J60_RS28275	COG0673	inositol 2-dehydrogenase activity
K1J60_RS28360	COG3842	ATPase activity
K1J60_RS28370	COG1840	ABC-type Fe3 transport system, periplasmic component
K1J60_RS28380	COG1674	ftsk spoiiie
K1J60_RS28415	COG1869	D-ribose catabolic process
K1J60_RS28430	COG1129	ABC transporter
K1J60_RS28460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K1J60_RS28485	COG2409	Drug exporters of the RND superfamily
K1J60_RS28510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K1J60_RS28520	COG3718	enzyme involved in inositol metabolism
K1J60_RS28525	COG3962	Belongs to the TPP enzyme family
K1J60_RS28575	COG0492	ferredoxin-NADP+ reductase activity
K1J60_RS28600	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS28625	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS28645	COG2304	oxidoreductase activity
K1J60_RS28710	COG3547	Transposase (IS116 IS110 IS902 family)
K1J60_RS28715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K1J60_RS28790	COG0629	single-stranded DNA binding
K1J60_RS28820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K1J60_RS28835	COG0631	protein serine/threonine phosphatase activity
K1J60_RS28850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K1J60_RS28865	COG1486	melibiose metabolic process
K1J60_RS28870	COG0395	ABC-type sugar transport system, permease component
K1J60_RS28875	COG1175	transmembrane transport
K1J60_RS28885	COG1940	carbohydrate kinase activity
K1J60_RS28900	COG0668	transmembrane transport
K1J60_RS28940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K1J60_RS28945	COG1846	Transcriptional regulator
K1J60_RS28950	COG0697	spore germination
K1J60_RS29005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K1J60_RS29015	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K1J60_RS29020	COG1113	amino acid transport
K1J60_RS29030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K1J60_RS29035	COG1116	anion transmembrane transporter activity
K1J60_RS29040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K1J60_RS29070	COG0515	serine threonine protein kinase
K1J60_RS29075	COG1113	amino acid transport
K1J60_RS29090	COG4552	Acetyltransferase involved in intracellular survival and related
K1J60_RS29105	COG3594	Acyltransferase
K1J60_RS29125	COG0544	peptidyl-prolyl cis-trans isomerase activity
K1J60_RS29130	COG0740	serine-type endopeptidase activity
K1J60_RS29135	COG0740	serine-type endopeptidase activity
K1J60_RS29140	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K1J60_RS29155	COG0525	valine-tRNA ligase activity
K1J60_RS29160	COG0285	dihydrofolate synthase activity
K1J60_RS29170	COG0105	UTP biosynthetic process
K1J60_RS29175	COG1077	Cell shape determining protein MreB Mrl
K1J60_RS29190	COG0768	penicillin binding
K1J60_RS29195	COG0772	Belongs to the SEDS family
K1J60_RS29235	COG0457	Tetratricopeptide repeat
K1J60_RS29235	COG0463	Glycosyl transferase, family 2
K1J60_RS29250	COG1530	ribonuclease E activity
K1J60_RS29260	COG0261	This protein binds to 23S rRNA in the presence of protein L20
K1J60_RS29265	COG0211	Belongs to the bacterial ribosomal protein bL27 family
K1J60_RS29270	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K1J60_RS29280	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K1J60_RS29290	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
K1J60_RS29305	COG0501	Belongs to the peptidase M48B family
K1J60_RS29320	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
K1J60_RS29330	COG0799	negative regulation of ribosome biogenesis
K1J60_RS29335	COG0588	phosphoglycerate mutase activity
K1J60_RS29355	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K1J60_RS29365	COG0495	leucyl-tRNA aminoacylation
K1J60_RS29375	COG1307	EDD domain protein, DegV family
K1J60_RS29380	COG1555	photosystem II stabilization
K1J60_RS29410	COG0268	Binds directly to 16S ribosomal RNA
K1J60_RS29415	COG0481	GTPase activity
K1J60_RS29470	COG1420	regulation of RNA biosynthetic process
K1J60_RS29475	COG0484	heat shock protein binding
K1J60_RS29495	COG0793	Belongs to the peptidase S41A family
K1J60_RS29495	COG4946	Tricorn protease homolog
K1J60_RS29500	COG0537	adenosine 5'-monophosphoramidase activity
K1J60_RS29505	COG1234	tRNA 3'-trailer cleavage
K1J60_RS29510	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K1J60_RS29525	COG4948	Mandelate Racemase Muconate Lactonizing
K1J60_RS29535	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K1J60_RS29575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K1J60_RS29595	COG2723	6-phospho-beta-galactosidase activity
K1J60_RS29610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K1J60_RS29620	COG2124	cytochrome p450
K1J60_RS29625	COG2409	Drug exporters of the RND superfamily
K1J60_RS29630	COG4585	Histidine kinase
K1J60_RS29635	COG2197	response regulator
K1J60_RS29640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K1J60_RS29645	COG4608	Belongs to the ABC transporter superfamily
K1J60_RS29650	COG0444	Belongs to the ABC transporter superfamily
K1J60_RS29660	COG0747	negative chemotaxis
K1J60_RS29665	COG2186	Transcriptional regulator
K1J60_RS29680	COG3903	Transcriptional regulator
K1J60_RS29680	COG3629	intracellular signal transduction
K1J60_RS29690	COG1381	Involved in DNA repair and RecF pathway recombination
K1J60_RS29695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K1J60_RS29710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K1J60_RS29715	COG1121	(ABC) transporter
K1J60_RS29720	COG3443	Belongs to the bacterial solute-binding protein 9 family
K1J60_RS29720	COG0803	Belongs to the bacterial solute-binding protein 9 family
K1J60_RS29725	COG0423	glycine-tRNA ligase activity
K1J60_RS29765	COG0667	Aldo Keto reductase
K1J60_RS29815	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
K1J60_RS29820	COG1940	carbohydrate kinase activity
K1J60_RS29820	COG1846	Transcriptional regulator
K1J60_RS29825	COG0574	Belongs to the PEP-utilizing enzyme family
K1J60_RS29825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K1J60_RS29835	COG1136	(ABC) transporter
K1J60_RS29845	COG1595	DNA-templated transcription, initiation
K1J60_RS29880	COG0642	Histidine kinase
K1J60_RS29895	COG0659	secondary active sulfate transmembrane transporter activity
K1J60_RS29910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K1J60_RS29910	COG2146	nitrite reductase [NAD(P)H] activity
K1J60_RS29915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K1J60_RS29945	COG0701	Predicted permease
K1J60_RS29980	COG0243	molybdopterin cofactor binding
K1J60_RS29990	COG2949	membrane
K1J60_RS30000	COG0232	Belongs to the dGTPase family. Type 2 subfamily
K1J60_RS30010	COG0358	DNA primase activity
K1J60_RS30015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K1J60_RS30030	COG1070	Carbohydrate kinase
K1J60_RS30080	COG1475	DNA binding
K1J60_RS30180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K1J60_RS30185	COG0573	inorganic phosphate transmembrane transporter activity
K1J60_RS30195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K1J60_RS30210	COG0446	pyridine nucleotide-disulphide oxidoreductase
K1J60_RS30225	COG3118	belongs to the thioredoxin family
K1J60_RS30230	COG0492	ferredoxin-NADP+ reductase activity
K1J60_RS30235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K1J60_RS30245	COG0798	PFAM Bile acid sodium symporter
K1J60_RS30255	COG2072	flavoprotein involved in K transport
K1J60_RS30260	COG0640	Transcriptional regulator
K1J60_RS30265	COG2072	flavoprotein involved in K transport
K1J60_RS30340	COG2175	clavaminate synthase activity
K1J60_RS30345	COG1215	transferase activity, transferring glycosyl groups
K1J60_RS30360	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS30625	COG1959	2 iron, 2 sulfur cluster binding
K1J60_RS30640	COG3629	intracellular signal transduction
K1J60_RS30640	COG3903	Transcriptional regulator
K1J60_RS30680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K1J60_RS30690	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
K1J60_RS30730	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS30740	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
K1J60_RS30745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K1J60_RS30765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K1J60_RS30790	COG3328	transposase activity
K1J60_RS30820	COG0501	Belongs to the peptidase M48B family
K1J60_RS30865	COG1609	Transcriptional regulator
K1J60_RS30875	COG0492	ferredoxin-NADP+ reductase activity
K1J60_RS30880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K1J60_RS30885	COG0640	Transcriptional regulator
K1J60_RS30900	COG4585	Histidine kinase
K1J60_RS30905	COG2197	response regulator
K1J60_RS30925	COG1846	Transcriptional regulator
K1J60_RS30960	COG0477	Major facilitator Superfamily
K1J60_RS30970	COG0675	Transposase, IS605 OrfB family
K1J60_RS30980	COG1053	succinate dehydrogenase
K1J60_RS30990	COG3903	Transcriptional regulator
K1J60_RS30990	COG3629	intracellular signal transduction
K1J60_RS31005	COG0641	radical SAM
K1J60_RS31020	COG1077	Cell shape determining protein MreB Mrl
K1J60_RS31030	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS31040	COG2186	Transcriptional regulator
K1J60_RS31085	COG2835	tetraacyldisaccharide 4'-kinase activity
K1J60_RS31105	COG4981	capsule polysaccharide biosynthetic process
K1J60_RS31135	COG1414	Transcriptional regulator
K1J60_RS31140	COG3386	PFAM SMP-30 Gluconolaconase
K1J60_RS31175	COG0730	response to heat
K1J60_RS31220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K1J60_RS31230	COG4214	carbohydrate transport
K1J60_RS31260	COG1609	Transcriptional regulator
K1J60_RS31265	COG1879	ABC-type sugar transport system periplasmic component
K1J60_RS31275	COG1172	Belongs to the binding-protein-dependent transport system permease family
K1J60_RS31280	COG1172	Belongs to the binding-protein-dependent transport system permease family
K1J60_RS31310	COG2130	NADP-dependent
K1J60_RS31390	COG1309	transcriptional regulator
K1J60_RS31415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K1J60_RS31420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K1J60_RS31425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K1J60_RS31440	COG1741	Belongs to the pirin family
K1J60_RS31475	COG2003	Belongs to the UPF0758 family
K1J60_RS31510	COG0789	Transcriptional regulator
K1J60_RS31515	COG0667	Aldo Keto reductase
K1J60_RS31530	COG1309	transcriptional regulator
K1J60_RS31535	COG0477	Major facilitator Superfamily
K1J60_RS31545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K1J60_RS31550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
K1J60_RS31595	COG1358	cellular component organization or biogenesis
K1J60_RS31605	COG0586	Pfam SNARE associated Golgi protein
K1J60_RS31615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K1J60_RS31650	COG3345	alpha-galactosidase
K1J60_RS31665	COG0583	DNA-binding transcription factor activity
K1J60_RS31670	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K1J60_RS31720	COG1733	regulation of RNA biosynthetic process
K1J60_RS31775	COG4122	O-methyltransferase activity
K1J60_RS31795	COG2124	cytochrome p450
K1J60_RS31800	COG0183	Belongs to the thiolase family
K1J60_RS31805	COG2319	Wd-40 repeat
K1J60_RS31805	COG4249	Peptidase C14 caspase catalytic subunit p20
K1J60_RS31820	COG3845	ABC transporter
K1J60_RS31860	COG1309	transcriptional regulator
K1J60_RS31865	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS31885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K1J60_RS31895	COG0860	N-Acetylmuramoyl-L-alanine amidase
K1J60_RS31925	COG2030	dehydratase
K1J60_RS31935	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS31950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K1J60_RS31965	COG0800	Aldolase
K1J60_RS31970	COG3022	response to hydroperoxide
K1J60_RS32110	COG0189	ligase activity
K1J60_RS32115	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K1J60_RS32120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K1J60_RS32190	COG1201	RNA secondary structure unwinding
K1J60_RS32220	COG3940	Belongs to the glycosyl hydrolase 43 family
K1J60_RS32225	COG3940	Belongs to the glycosyl hydrolase 43 family
K1J60_RS32230	COG2197	response regulator
K1J60_RS32235	COG4585	Histidine kinase
K1J60_RS32240	COG2409	Drug exporters of the RND superfamily
K1J60_RS32255	COG2259	Doxx family
K1J60_RS32265	COG0667	Aldo Keto reductase
K1J60_RS32275	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS32280	COG3540	Alkaline phosphatase
K1J60_RS32290	COG2814	Major facilitator Superfamily
K1J60_RS32295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K1J60_RS32300	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
K1J60_RS32350	COG1120	ATPase activity
K1J60_RS32355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K1J60_RS32400	COG1994	Peptidase M50
K1J60_RS32420	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
K1J60_RS32425	COG0477	Major facilitator Superfamily
K1J60_RS32440	COG2814	Major facilitator Superfamily
K1J60_RS32455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K1J60_RS32455	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
K1J60_RS32470	COG0174	glutamine synthetase
K1J60_RS32500	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
K1J60_RS32510	COG0583	DNA-binding transcription factor activity
K1J60_RS32520	COG1609	Transcriptional regulator
K1J60_RS32530	COG1175	transmembrane transport
K1J60_RS32535	COG3833	ABC-type maltose transport systems, permease component
K1J60_RS32540	COG0366	Alpha amylase catalytic
K1J60_RS32570	COG1309	transcriptional regulator
K1J60_RS32600	COG0745	RESPONSE REGULATOR receiver
K1J60_RS32665	COG0174	glutamine synthetase
K1J60_RS32685	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K1J60_RS32690	COG0321	lipoyl(octanoyl) transferase activity
K1J60_RS32715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K1J60_RS32740	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
K1J60_RS32750	COG0508	dehydrogenase complex catalyzes the overall conversion of
K1J60_RS32755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K1J60_RS32760	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K1J60_RS32770	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS32790	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
K1J60_RS32805	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
K1J60_RS32825	COG2226	methyltransferase
K1J60_RS32845	COG4585	Histidine kinase
K1J60_RS32850	COG2197	response regulator
K1J60_RS32855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K1J60_RS32860	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K1J60_RS32860	COG0515	serine threonine protein kinase
K1J60_RS32865	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
K1J60_RS32885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K1J60_RS32895	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K1J60_RS32900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K1J60_RS32910	COG1376	ErfK ybiS ycfS ynhG family protein
K1J60_RS32920	COG1845	cytochrome c oxidase, subunit III
K1J60_RS32925	COG2010	Cytochrome c
K1J60_RS32930	COG0723	plastoquinol--plastocyanin reductase activity
K1J60_RS32935	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K1J60_RS32940	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K1J60_RS32945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K1J60_RS32990	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS33015	COG0003	Pfam Anion-transporting ATPase
K1J60_RS33025	COG1940	carbohydrate kinase activity
K1J60_RS33060	COG4585	Histidine kinase
K1J60_RS33070	COG0205	6-phosphofructokinase activity
K1J60_RS33090	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
K1J60_RS33095	COG0243	molybdopterin cofactor binding
K1J60_RS33100	COG2193	ferroxidase activity
K1J60_RS33105	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K1J60_RS33110	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
K1J60_RS33115	COG0515	serine threonine protein kinase
K1J60_RS33115	COG2815	serine threonine protein kinase
K1J60_RS33120	COG2022	thiamine diphosphate biosynthetic process
K1J60_RS33130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K1J60_RS33130	COG2022	thiamine diphosphate biosynthetic process
K1J60_RS33140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K1J60_RS33150	COG0352	thiamine-phosphate diphosphorylase activity
K1J60_RS33165	COG1233	COG1233 Phytoene dehydrogenase and related
K1J60_RS33170	COG1309	transcriptional regulator
K1J60_RS33180	COG1122	ATPase activity
K1J60_RS33190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K1J60_RS33210	COG0714	Associated with various cellular activities
K1J60_RS33220	COG0275	rRNA processing
K1J60_RS33235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K1J60_RS33245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K1J60_RS33250	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
K1J60_RS33260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K1J60_RS33265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K1J60_RS33270	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K1J60_RS33275	COG1496	oxidoreductase activity
K1J60_RS33280	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K1J60_RS33285	COG1799	cell septum assembly
K1J60_RS33295	COG3599	regulation of cell shape
K1J60_RS33300	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K1J60_RS33310	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K1J60_RS33330	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS33375	COG0587	DNA-directed DNA polymerase activity
K1J60_RS33385	COG1432	Conserved Protein
K1J60_RS33405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K1J60_RS33425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K1J60_RS33430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K1J60_RS33435	COG0131	Imidazoleglycerol-phosphate dehydratase
K1J60_RS33445	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K1J60_RS33450	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K1J60_RS33455	COG0251	oxidation-reduction process
K1J60_RS33460	COG0107	imidazoleglycerol-phosphate synthase activity
K1J60_RS33470	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K1J60_RS33475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K1J60_RS33495	COG0134	indole-3-glycerol-phosphate synthase activity
K1J60_RS33500	COG0133	tryptophan synthase activity
K1J60_RS33505	COG0159	tryptophan synthase activity
K1J60_RS33515	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
K1J60_RS33525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K1J60_RS33555	COG0067	glutamate synthase
K1J60_RS33555	COG0070	glutamate synthase
K1J60_RS33555	COG0069	glutamate synthase activity
K1J60_RS33570	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS33575	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS33580	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS33585	COG1309	transcriptional regulator
K1J60_RS33590	COG0183	Belongs to the thiolase family
K1J60_RS33620	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS33630	COG0287	Prephenate dehydrogenase
K1J60_RS33630	COG1605	Chorismate mutase
K1J60_RS33635	COG4566	intracellular signal transduction
K1J60_RS33660	COG0737	Belongs to the 5'-nucleotidase family
K1J60_RS33695	COG0411	ABC transporter
K1J60_RS33705	COG0559	Belongs to the binding-protein-dependent transport system permease family
K1J60_RS33725	COG2050	protein possibly involved in aromatic compounds catabolism
K1J60_RS33760	COG1643	Atp-dependent helicase
K1J60_RS33770	COG0539	negative regulation of cytoplasmic translation
K1J60_RS33780	COG0237	dephospho-CoA kinase activity
K1J60_RS33800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K1J60_RS33820	COG2267	carboxylic ester hydrolase activity
K1J60_RS33825	COG1802	Transcriptional regulator
K1J60_RS33830	COG1953	Uracil, thiamine, allantoin
K1J60_RS33860	COG0402	S-adenosylhomocysteine deaminase activity
K1J60_RS33910	COG3848	Pyruvate phosphate dikinase
K1J60_RS33910	COG0574	Belongs to the PEP-utilizing enzyme family
K1J60_RS33910	COG3848	Pyruvate phosphate dikinase
K1J60_RS33910	COG0574	Belongs to the PEP-utilizing enzyme family
K1J60_RS33915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K1J60_RS33920	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K1J60_RS33950	COG0598	Magnesium transport protein CorA
K1J60_RS33965	COG2313	pseudouridylate synthase activity
K1J60_RS33975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K1J60_RS33980	COG0584	glycerophosphoryl diester phosphodiesterase
K1J60_RS33990	COG0556	nucleotide-excision repair
K1J60_RS34010	COG0387	Pfam Sodium calcium exchanger
K1J60_RS34015	COG0477	Major facilitator Superfamily
K1J60_RS34020	COG1619	proteins homologs of microcin C7 resistance protein MccF
K1J60_RS34025	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
K1J60_RS34035	COG0765	amino acid transport
K1J60_RS34040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K1J60_RS34050	COG0596	Alpha beta hydrolase
K1J60_RS34070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K1J60_RS34085	COG2197	response regulator
K1J60_RS34100	COG4585	Histidine kinase
K1J60_RS34105	COG2197	response regulator
K1J60_RS34110	COG0322	excinuclease ABC activity
K1J60_RS34115	COG1660	Displays ATPase and GTPase activities
K1J60_RS34120	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K1J60_RS34125	COG1481	regulation of sporulation
K1J60_RS34135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K1J60_RS34140	COG0126	phosphoglycerate kinase activity
K1J60_RS34145	COG0149	triose-phosphate isomerase activity
K1J60_RS34150	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K1J60_RS34165	COG0166	Belongs to the GPI family
K1J60_RS34170	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS34175	COG0477	Major facilitator Superfamily
K1J60_RS34180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K1J60_RS34200	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS34210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K1J60_RS34220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K1J60_RS34225	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS34240	COG0477	Major facilitator Superfamily
K1J60_RS34245	COG0363	glucosamine-6-phosphate deaminase activity
K1J60_RS34260	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K1J60_RS34265	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K1J60_RS34270	COG0109	protoheme IX farnesyltransferase activity
K1J60_RS34290	COG1612	heme a metabolic process
K1J60_RS34300	COG1131	(ABC) transporter
K1J60_RS34305	COG2746	aminoglycoside 3-N-acetyltransferase activity
K1J60_RS34320	COG0719	Fe-S assembly protein
K1J60_RS34330	COG0396	ATPase activity
K1J60_RS34335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K1J60_RS34340	COG0822	iron-sulfur transferase activity
K1J60_RS34345	COG2151	metal-sulfur cluster biosynthetic enzyme
K1J60_RS34355	COG2076	Multidrug Resistance protein
K1J60_RS34360	COG3226	Transcriptional regulator
K1J60_RS34375	COG2171	N-acyltransferase activity
K1J60_RS34395	COG1595	DNA-templated transcription, initiation
K1J60_RS34405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K1J60_RS34420	COG1959	2 iron, 2 sulfur cluster binding
K1J60_RS34420	COG1295	ribonuclease BN
K1J60_RS34460	COG1802	Transcriptional regulator
K1J60_RS34465	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K1J60_RS34480	COG1063	alcohol dehydrogenase
K1J60_RS34485	COG0395	ABC-type sugar transport system, permease component
K1J60_RS34500	COG1349	DNA-binding transcription factor activity
K1J60_RS34505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K1J60_RS34510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K1J60_RS34540	COG1802	Transcriptional regulator
K1J60_RS34545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K1J60_RS34555	COG1175	transmembrane transport
K1J60_RS34560	COG0395	ABC-type sugar transport system, permease component
K1J60_RS34565	COG3866	Pectate lyase
K1J60_RS34580	COG3507	Belongs to the glycosyl hydrolase 43 family
K1J60_RS34585	COG4677	pectinesterase activity
K1J60_RS34595	COG2755	lipolytic protein G-D-S-L family
K1J60_RS34605	COG4677	pectinesterase activity
K1J60_RS34610	COG4677	pectinesterase activity
K1J60_RS34635	COG4733	cellulase activity
K1J60_RS34650	COG1595	DNA-templated transcription, initiation
K1J60_RS34655	COG2252	PERMEase
K1J60_RS34665	COG1414	Transcriptional regulator
K1J60_RS34700	COG5285	phytanoyl-CoA dioxygenase
K1J60_RS34705	COG1917	Cupin 2, conserved barrel domain protein
K1J60_RS34710	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K1J60_RS34715	COG0456	acetyltransferase
K1J60_RS34720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K1J60_RS34725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K1J60_RS34730	COG0765	amino acid transport
K1J60_RS34735	COG1126	abc transporter atp-binding protein
K1J60_RS34760	COG4209	transmembrane transport
K1J60_RS34765	COG0395	ABC-type sugar transport system, permease component
K1J60_RS34775	COG1609	Transcriptional regulator
K1J60_RS34795	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
K1J60_RS34810	COG1797	cobyrinic acid a,c-diamide synthase activity
K1J60_RS34825	COG1492	cobalamin metabolic process
K1J60_RS34830	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
K1J60_RS34870	COG0235	Class ii aldolase
K1J60_RS34890	COG0488	(ABC) transporter
K1J60_RS34940	COG3387	PFAM Glycoside hydrolase 15-related
K1J60_RS34965	COG1966	Carbon starvation protein
K1J60_RS34990	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K1J60_RS35010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K1J60_RS35015	COG1404	Belongs to the peptidase S8 family
K1J60_RS35030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K1J60_RS35035	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K1J60_RS35055	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K1J60_RS35070	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS35085	COG2186	Transcriptional regulator
K1J60_RS35100	COG0588	phosphoglycerate mutase activity
K1J60_RS35105	COG0560	Phosphoserine phosphatase
K1J60_RS35105	COG3830	Belongs to the UPF0237 family
K1J60_RS35115	COG1716	ATPase activity
K1J60_RS35115	COG0842	Transport permease protein
K1J60_RS35115	COG1131	(ABC) transporter
K1J60_RS35125	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K1J60_RS35130	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS35140	COG2197	response regulator
K1J60_RS35160	COG1119	ATPase activity
K1J60_RS35180	COG1881	PFAM PEBP family protein
K1J60_RS35190	COG2094	Belongs to the DNA glycosylase MPG family
K1J60_RS35225	COG0647	UMP catabolic process
K1J60_RS35230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K1J60_RS35235	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K1J60_RS35240	COG1120	ATPase activity
K1J60_RS35260	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K1J60_RS35265	COG0497	DNA recombination
K1J60_RS35270	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS35285	COG3387	PFAM Glycoside hydrolase 15-related
K1J60_RS35290	COG0504	CTP synthase activity
K1J60_RS35295	COG0494	nUDIX hydrolase
K1J60_RS35305	COG0686	Belongs to the AlaDH PNT family
K1J60_RS35320	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
K1J60_RS35325	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K1J60_RS35330	COG1187	pseudouridine synthase activity
K1J60_RS35335	COG0494	nUDIX hydrolase
K1J60_RS35345	COG3541	Predicted nucleotidyltransferase
K1J60_RS35380	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
K1J60_RS35390	COG1160	GTP binding
K1J60_RS35405	COG1652	LysM domain
K1J60_RS35435	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS35445	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K1J60_RS35455	COG0671	phosphoesterase, PA-phosphatase related
K1J60_RS35465	COG0477	Major facilitator Superfamily
K1J60_RS35470	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS35475	COG1799	cell septum assembly
K1J60_RS35505	COG0587	DNA-directed DNA polymerase activity
K1J60_RS35510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K1J60_RS35530	COG4106	trans-aconitate 2-methyltransferase activity
K1J60_RS35545	COG1725	Transcriptional regulator
K1J60_RS35570	COG0726	polysaccharide deacetylase
K1J60_RS35580	COG0463	Glycosyl transferase, family 2
K1J60_RS35600	COG2755	lipolytic protein G-D-S-L family
K1J60_RS35625	COG1595	DNA-templated transcription, initiation
K1J60_RS35640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K1J60_RS35665	COG2188	Transcriptional regulator
K1J60_RS35670	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
K1J60_RS35675	COG1309	transcriptional regulator
K1J60_RS35680	COG0243	molybdopterin cofactor binding
K1J60_RS35685	COG2851	Citrate transporter
K1J60_RS35730	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS35760	COG0789	Transcriptional regulator
K1J60_RS35765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K1J60_RS35765	COG0072	phenylalanine-tRNA ligase activity
K1J60_RS35790	COG3876	Protein conserved in bacteria
K1J60_RS35805	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS35830	COG2149	membrane
K1J60_RS35835	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
K1J60_RS35845	COG3573	Dehydrogenase
K1J60_RS35850	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K1J60_RS35865	COG3265	gluconokinase activity
K1J60_RS35870	COG2186	Transcriptional regulator
K1J60_RS35875	COG3012	SEC-C Motif Domain Protein
K1J60_RS35880	COG0308	aminopeptidase N
K1J60_RS35925	COG0667	Aldo Keto reductase
K1J60_RS35930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K1J60_RS35940	COG0598	Magnesium transport protein CorA
K1J60_RS35945	COG0588	phosphoglycerate mutase activity
K1J60_RS35960	COG0215	cysteine-tRNA ligase activity
K1J60_RS35975	COG2186	Transcriptional regulator
K1J60_RS35980	COG0402	S-adenosylhomocysteine deaminase activity
K1J60_RS35990	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K1J60_RS35995	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K1J60_RS36000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K1J60_RS36005	COG1414	Transcriptional regulator
K1J60_RS36010	COG1410	methionine synthase
K1J60_RS36010	COG0646	methionine synthase
K1J60_RS36020	COG4166	transmembrane transport
K1J60_RS36025	COG4166	transmembrane transport
K1J60_RS36030	COG2197	response regulator
K1J60_RS36040	COG1994	Peptidase M50
K1J60_RS36040	COG0517	IMP dehydrogenase activity
K1J60_RS36060	COG1222	aaa ATPase
K1J60_RS36065	COG4122	O-methyltransferase activity
K1J60_RS36080	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
K1J60_RS36085	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
K1J60_RS36090	COG1609	Transcriptional regulator
K1J60_RS36100	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
K1J60_RS36135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K1J60_RS36140	COG0805	protein transport
K1J60_RS36170	COG1309	transcriptional regulator
K1J60_RS36200	COG0564	pseudouridine synthase activity
K1J60_RS36265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K1J60_RS36290	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K1J60_RS36295	COG0531	amino acid
K1J60_RS36305	COG0174	glutamine synthetase
K1J60_RS36310	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS36335	COG1404	Belongs to the peptidase S8 family
K1J60_RS36355	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
K1J60_RS36360	COG0291	Belongs to the bacterial ribosomal protein bL35 family
K1J60_RS36365	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K1J60_RS36370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K1J60_RS36375	COG5002	protein histidine kinase activity
K1J60_RS36380	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K1J60_RS36385	COG0072	phenylalanine-tRNA ligase activity
K1J60_RS36385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K1J60_RS36415	COG1649	PFAM Uncharacterised BCR, COG1649
K1J60_RS36425	COG0697	spore germination
K1J60_RS36475	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K1J60_RS36480	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
K1J60_RS36485	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K1J60_RS36490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K1J60_RS36495	COG1438	arginine binding
K1J60_RS36525	COG0165	Argininosuccinate lyase
K1J60_RS36540	COG0477	Major facilitator Superfamily
K1J60_RS36545	COG0204	Acyl-transferase
K1J60_RS36545	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS36550	COG0584	glycerophosphoryl diester phosphodiesterase
K1J60_RS36575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K1J60_RS36580	COG2011	ABC-type metal ion transport system permease component
K1J60_RS36585	COG1464	Belongs to the NlpA lipoprotein family
K1J60_RS36600	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
K1J60_RS36605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K1J60_RS36605	COG1648	precorrin-2 dehydrogenase activity
K1J60_RS36665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K1J60_RS36665	COG0512	Glutamine amidotransferase of anthranilate synthase
K1J60_RS36720	COG1175	transmembrane transport
K1J60_RS36725	COG0395	ABC-type sugar transport system, permease component
K1J60_RS36755	COG2176	DNA-directed DNA polymerase activity
K1J60_RS36755	COG5002	protein histidine kinase activity
K1J60_RS36770	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K1J60_RS36795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K1J60_RS36800	COG1560	Kdo2-lipid A biosynthetic process
K1J60_RS36805	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS36815	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
K1J60_RS36820	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
K1J60_RS36825	COG0217	transcriptional regulatory protein
K1J60_RS36830	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
K1J60_RS36835	COG0632	four-way junction helicase activity
K1J60_RS36840	COG2255	four-way junction helicase activity
K1J60_RS36850	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K1J60_RS36855	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K1J60_RS36860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K1J60_RS36865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K1J60_RS36875	COG1196	nuclear chromosome segregation
K1J60_RS36880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K1J60_RS36890	COG0124	histidyl-tRNA synthetase
K1J60_RS36905	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
K1J60_RS36920	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K1J60_RS36925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K1J60_RS36930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K1J60_RS36935	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
K1J60_RS36950	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K1J60_RS36955	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K1J60_RS36960	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
K1J60_RS36970	COG0006	proline dipeptidase activity
K1J60_RS36975	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K1J60_RS36980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K1J60_RS36990	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
K1J60_RS36995	COG0540	Belongs to the ATCase OTCase family
K1J60_RS37000	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K1J60_RS37010	COG0505	Belongs to the CarA family
K1J60_RS37015	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K1J60_RS37020	COG0167	dihydroorotate dehydrogenase activity
K1J60_RS37025	COG0284	orotidine-5'-phosphate decarboxylase activity
K1J60_RS37035	COG0194	GDP metabolic process
K1J60_RS37040	COG1758	RNA polymerase activity
K1J60_RS37050	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K1J60_RS37065	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K1J60_RS37075	COG2409	Drug exporters of the RND superfamily
K1J60_RS37080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K1J60_RS37085	COG2390	Transcriptional regulator
K1J60_RS37100	COG0531	amino acid
K1J60_RS37110	COG2188	Transcriptional regulator
K1J60_RS37120	COG1176	ABC-type spermidine putrescine transport system, permease component I
K1J60_RS37130	COG3842	ATPase activity
K1J60_RS37135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K1J60_RS37150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K1J60_RS37170	COG2223	nitrite transmembrane transporter activity
K1J60_RS37175	COG1846	Transcriptional regulator
K1J60_RS37175	COG1940	carbohydrate kinase activity
K1J60_RS37190	COG3201	nicotinamide mononucleotide transporter
K1J60_RS37195	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K1J60_RS37195	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K1J60_RS37200	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
K1J60_RS37205	COG0140	phosphoribosyl-ATP diphosphatase activity
K1J60_RS37210	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
K1J60_RS37250	COG1309	transcriptional regulator
K1J60_RS37260	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS37280	COG1216	Glycosyl transferase, family 2
K1J60_RS37295	COG2270	Major facilitator Superfamily
K1J60_RS37310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K1J60_RS37340	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS37350	COG1984	allophanate hydrolase subunit 2
K1J60_RS37355	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K1J60_RS37360	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
K1J60_RS37365	COG4336	lyase activity
K1J60_RS37370	COG2814	Major facilitator Superfamily
K1J60_RS37405	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS37420	COG2018	Roadblock/LC7 domain
K1J60_RS37435	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K1J60_RS37440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K1J60_RS37445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K1J60_RS37465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K1J60_RS37475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K1J60_RS37505	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K1J60_RS37545	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K1J60_RS37555	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K1J60_RS37555	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K1J60_RS37580	COG0384	phenazine biosynthesis protein PhzF
K1J60_RS37670	COG0697	spore germination
K1J60_RS37675	COG0583	DNA-binding transcription factor activity
K1J60_RS37695	COG1252	NADH dehydrogenase
K1J60_RS37700	COG1595	DNA-templated transcription, initiation
K1J60_RS37710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K1J60_RS37715	COG0179	Fumarylacetoacetate (FAA) hydrolase
K1J60_RS37755	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
K1J60_RS37770	COG2318	DinB family
K1J60_RS37780	COG0815	Transfers the fatty acyl group on membrane lipoproteins
K1J60_RS37795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K1J60_RS37815	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K1J60_RS37825	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS37840	COG1968	undecaprenyl-diphosphatase activity
K1J60_RS37865	COG0183	Belongs to the thiolase family
K1J60_RS37875	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K1J60_RS37915	COG0110	maltose O-acetyltransferase activity
K1J60_RS37940	COG0542	response to heat
K1J60_RS37965	COG1136	(ABC) transporter
K1J60_RS37970	COG1136	(ABC) transporter
K1J60_RS37975	COG1832	CoA-binding protein
K1J60_RS37990	COG1739	Uncharacterized protein family UPF0029
K1J60_RS37995	COG1132	(ABC) transporter
K1J60_RS38000	COG0420	3'-5' exonuclease activity
K1J60_RS38005	COG0419	ATPase involved in DNA repair
K1J60_RS38010	COG1522	sequence-specific DNA binding
K1J60_RS38035	COG0626	cystathionine gamma-synthase activity
K1J60_RS38050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K1J60_RS38060	COG0596	Alpha beta hydrolase
K1J60_RS38065	COG1595	DNA-templated transcription, initiation
K1J60_RS38070	COG2188	Transcriptional regulator
K1J60_RS38075	COG1940	carbohydrate kinase activity
K1J60_RS38085	COG3663	DNA glycosylase
K1J60_RS38090	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K1J60_RS38130	COG0577	efflux transmembrane transporter activity
K1J60_RS38130	COG1136	(ABC) transporter
K1J60_RS38135	COG0577	efflux transmembrane transporter activity
K1J60_RS38135	COG1136	(ABC) transporter
K1J60_RS38165	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
K1J60_RS38170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K1J60_RS38175	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
K1J60_RS38205	COG0791	NLP P60 protein
K1J60_RS38205	COG1388	LysM domain
K1J60_RS38215	COG0740	serine-type endopeptidase activity
K1J60_RS38230	COG1309	transcriptional regulator
K1J60_RS38235	COG0831	urea catabolic process
K1J60_RS38240	COG0832	Belongs to the urease beta subunit family
K1J60_RS38245	COG0804	urea catabolic process
K1J60_RS38255	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
K1J60_RS38260	COG0829	nickel cation binding
K1J60_RS38275	COG0204	Acyl-transferase
K1J60_RS38285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K1J60_RS38290	COG1834	amidinotransferase
K1J60_RS38300	COG3279	Response regulator of the LytR AlgR family
K1J60_RS38310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K1J60_RS38315	COG3275	phosphorelay sensor kinase activity
K1J60_RS38325	COG2815	serine threonine protein kinase
K1J60_RS38325	COG0515	serine threonine protein kinase
K1J60_RS38340	COG0205	6-phosphofructokinase activity
K1J60_RS38345	COG3442	glutamine amidotransferase
K1J60_RS38355	COG0242	peptide deformylase activity
K1J60_RS38365	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS38380	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS38390	COG1793	dna ligase
K1J60_RS38410	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS38415	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS38455	COG0642	Histidine kinase
K1J60_RS38500	COG1609	Transcriptional regulator
K1J60_RS38510	COG1846	Transcriptional regulator
K1J60_RS38535	COG3866	Pectate lyase
K1J60_RS38565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K1J60_RS38565	COG3321	synthase
K1J60_RS38565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K1J60_RS38565	COG3321	synthase
K1J60_RS38570	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS38575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K1J60_RS38605	COG2755	lipolytic protein G-D-S-L family
K1J60_RS38620	COG1472	Belongs to the glycosyl hydrolase 3 family
K1J60_RS38640	COG0395	ABC-type sugar transport system, permease component
K1J60_RS38645	COG1175	transmembrane transport
K1J60_RS38665	COG1737	Transcriptional regulator
K1J60_RS38670	COG4821	SIS domain
K1J60_RS38675	COG2409	Drug exporters of the RND superfamily
K1J60_RS38680	COG1231	oxidoreductase activity
K1J60_RS38705	COG3291	Pkd domain containing protein
K1J60_RS38705	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K1J60_RS38730	COG1172	Belongs to the binding-protein-dependent transport system permease family
K1J60_RS38775	COG3033	Beta-eliminating lyase
K1J60_RS38790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K1J60_RS38795	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS38805	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K1J60_RS38830	COG1063	alcohol dehydrogenase
K1J60_RS38845	COG0148	phosphopyruvate hydratase activity
K1J60_RS38855	COG1609	Transcriptional regulator
K1J60_RS38860	COG0179	Fumarylacetoacetate (FAA) hydrolase
K1J60_RS38865	COG2814	Major facilitator Superfamily
K1J60_RS38870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K1J60_RS38890	COG1703	isobutyryl-CoA mutase activity
K1J60_RS38890	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K1J60_RS38890	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K1J60_RS38900	COG0183	Belongs to the thiolase family
K1J60_RS38915	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS38920	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS38930	COG1063	alcohol dehydrogenase
K1J60_RS38935	COG1172	Belongs to the binding-protein-dependent transport system permease family
K1J60_RS38940	COG1129	ABC transporter
K1J60_RS38950	COG4638	Rieske (2fe-2S)
K1J60_RS38965	COG2130	NADP-dependent
K1J60_RS38980	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS38985	COG4638	Rieske (2fe-2S)
K1J60_RS38995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K1J60_RS39000	COG0022	dehydrogenase e1 component
K1J60_RS39005	COG0508	dehydrogenase complex catalyzes the overall conversion of
K1J60_RS39015	COG1309	transcriptional regulator
K1J60_RS39020	COG0300	oxidoreductase activity
K1J60_RS39035	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS39040	COG0574	Belongs to the PEP-utilizing enzyme family
K1J60_RS39040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K1J60_RS39050	COG1024	Enoyl-CoA hydratase
K1J60_RS39055	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS39120	COG1309	transcriptional regulator
K1J60_RS39135	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS39180	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS39185	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS39200	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS39205	COG1309	transcriptional regulator
K1J60_RS39220	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS39225	COG0515	serine threonine protein kinase
K1J60_RS39225	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K1J60_RS39250	COG0745	RESPONSE REGULATOR receiver
K1J60_RS39255	COG2205	protein histidine kinase activity
K1J60_RS39265	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
K1J60_RS39270	COG0745	RESPONSE REGULATOR receiver
K1J60_RS39275	COG2205	protein histidine kinase activity
K1J60_RS39310	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS39335	COG0183	Belongs to the thiolase family
K1J60_RS39345	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS39405	COG0300	oxidoreductase activity
K1J60_RS39450	COG0517	IMP dehydrogenase activity
K1J60_RS39450	COG0516	GMP reductase activity
K1J60_RS39475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K1J60_RS39480	COG0569	domain protein
K1J60_RS39495	COG0508	dehydrogenase complex catalyzes the overall conversion of
K1J60_RS39500	COG0508	dehydrogenase complex catalyzes the overall conversion of
K1J60_RS39500	COG0022	dehydrogenase e1 component
K1J60_RS39505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K1J60_RS39510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K1J60_RS39515	COG3383	formate dehydrogenase (NAD+) activity
K1J60_RS39555	COG3693	PFAM glycoside hydrolase, family 10
K1J60_RS39590	COG0583	DNA-binding transcription factor activity
K1J60_RS39600	COG1250	3-hydroxyacyl-CoA dehydrogenase
K1J60_RS39600	COG1024	Enoyl-CoA hydratase
K1J60_RS39615	COG4221	oxidoreductase activity
K1J60_RS39620	COG1902	pentaerythritol trinitrate reductase activity
K1J60_RS39640	COG3321	synthase
K1J60_RS39640	COG0604	alcohol dehydrogenase
K1J60_RS39650	COG1250	3-hydroxyacyl-CoA dehydrogenase
K1J60_RS39650	COG1024	Enoyl-CoA hydratase
K1J60_RS39655	COG1309	transcriptional regulator
K1J60_RS39660	COG2801	Transposase and inactivated derivatives
K1J60_RS39665	COG2801	Transposase and inactivated derivatives
K1J60_RS39705	COG2197	response regulator
K1J60_RS39730	COG0154	amidase activity
K1J60_RS39760	COG1136	(ABC) transporter
K1J60_RS39760	COG0577	efflux transmembrane transporter activity
K1J60_RS39765	COG4585	Histidine kinase
K1J60_RS39770	COG2197	response regulator
K1J60_RS39785	COG0475	glutathione-regulated potassium exporter activity
K1J60_RS39810	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS39825	COG1940	carbohydrate kinase activity
K1J60_RS39850	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K1J60_RS39900	COG2018	Roadblock/LC7 domain
K1J60_RS39910	COG1946	Acyl-CoA thioesterase
K1J60_RS39930	COG1132	(ABC) transporter
K1J60_RS39950	COG1301	dicarboxylic acid transport
K1J60_RS39960	COG1132	(ABC) transporter
K1J60_RS39965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K1J60_RS39970	COG0492	ferredoxin-NADP+ reductase activity
K1J60_RS39975	COG0432	Pfam Uncharacterised protein family UPF0047
K1J60_RS40020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
K1J60_RS40050	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
K1J60_RS40095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K1J60_RS40125	COG2318	DinB family
K1J60_RS40180	COG2308	Evidence 4 Homologs of previously reported genes of
K1J60_RS40180	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
K1J60_RS40190	COG1595	DNA-templated transcription, initiation
K1J60_RS40200	COG1131	(ABC) transporter
K1J60_RS40235	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS40255	COG1063	alcohol dehydrogenase
K1J60_RS40265	COG0129	dihydroxy-acid dehydratase activity
K1J60_RS40270	COG2197	response regulator
K1J60_RS40275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K1J60_RS40310	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS40320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K1J60_RS40320	COG3320	Male sterility
K1J60_RS40335	COG2175	clavaminate synthase activity
K1J60_RS40340	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K1J60_RS40345	COG0667	Aldo Keto reductase
K1J60_RS40365	COG1733	regulation of RNA biosynthetic process
K1J60_RS40380	COG0477	Major facilitator Superfamily
K1J60_RS40425	COG1316	TRANSCRIPTIONal
K1J60_RS40435	COG3835	regulator
K1J60_RS40440	COG0135	phosphoribosylanthranilate isomerase activity
K1J60_RS40460	COG1174	glycine betaine transport
K1J60_RS40465	COG1174	glycine betaine transport
K1J60_RS40485	COG3250	beta-galactosidase activity
K1J60_RS40495	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K1J60_RS40505	COG4172	Belongs to the ABC transporter superfamily
K1J60_RS40510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K1J60_RS40520	COG4166	transmembrane transport
K1J60_RS40535	COG4948	Mandelate Racemase Muconate Lactonizing
K1J60_RS40540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K1J60_RS40550	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K1J60_RS40560	COG0714	Associated with various cellular activities
K1J60_RS40660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K1J60_RS40665	COG4948	Mandelate Racemase Muconate Lactonizing
K1J60_RS40690	COG3396	Phenylacetate-CoA oxygenase
K1J60_RS40695	COG3460	Phenylacetate-CoA oxygenase
K1J60_RS40700	COG3396	Phenylacetate-CoA oxygenase
K1J60_RS40705	COG2151	metal-sulfur cluster biosynthetic enzyme
K1J60_RS40710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K1J60_RS40740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K1J60_RS40755	COG2706	6-phosphogluconolactonase activity
K1J60_RS40770	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
K1J60_RS40805	COG3509	depolymerase
K1J60_RS40820	COG1902	pentaerythritol trinitrate reductase activity
K1J60_RS40825	COG0640	Transcriptional regulator
K1J60_RS40860	COG0671	phosphoesterase, PA-phosphatase related
K1J60_RS40880	COG1846	Transcriptional regulator
K1J60_RS40900	COG0584	glycerophosphoryl diester phosphodiesterase
K1J60_RS40950	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K1J60_RS40965	COG0515	serine threonine protein kinase
K1J60_RS41000	COG0445	tRNA wobble uridine modification
K1J60_RS41070	COG1349	DNA-binding transcription factor activity
K1J60_RS41075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K1J60_RS41090	COG2813	Specifically methylates the guanine in position
K1J60_RS41100	COG1940	carbohydrate kinase activity
K1J60_RS41110	COG0463	Glycosyl transferase, family 2
K1J60_RS41125	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K1J60_RS41145	COG1349	DNA-binding transcription factor activity
K1J60_RS41185	COG1215	transferase activity, transferring glycosyl groups
K1J60_RS41190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K1J60_RS41230	COG1129	ABC transporter
K1J60_RS41255	COG2814	Major facilitator Superfamily
K1J60_RS41265	COG3962	Belongs to the TPP enzyme family
K1J60_RS41270	COG3718	enzyme involved in inositol metabolism
K1J60_RS41280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K1J60_RS41285	COG1082	Xylose isomerase domain protein TIM barrel
K1J60_RS41305	COG1609	Transcriptional regulator
K1J60_RS41350	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS41365	COG1136	(ABC) transporter
K1J60_RS41380	COG2197	response regulator
K1J60_RS41395	COG0714	Associated with various cellular activities
K1J60_RS41425	COG0438	transferase activity, transferring glycosyl groups
K1J60_RS41435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K1J60_RS41440	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K1J60_RS41465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K1J60_RS41480	COG1864	DNA RNA non-specific endonuclease
K1J60_RS41480	COG3591	Belongs to the peptidase S1B family
K1J60_RS41500	COG1846	Transcriptional regulator
K1J60_RS41510	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K1J60_RS41515	COG3281	Trehalose synthase
K1J60_RS41520	COG0366	Alpha amylase catalytic
K1J60_RS41525	COG0366	Alpha amylase catalytic
K1J60_RS41555	COG0395	ABC-type sugar transport system, permease component
K1J60_RS41590	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K1J60_RS41595	COG1993	acr, cog1993
K1J60_RS41600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K1J60_RS41605	COG1968	undecaprenyl-diphosphatase activity
K1J60_RS41615	COG1113	amino acid transport
K1J60_RS41630	COG2066	Belongs to the glutaminase family
K1J60_RS41640	COG1686	Belongs to the peptidase S11 family
K1J60_RS41645	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K1J60_RS41655	COG0366	Alpha amylase catalytic
K1J60_RS41660	COG2226	methyltransferase
K1J60_RS41665	COG0596	Alpha beta hydrolase
K1J60_RS41670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K1J60_RS41675	COG3458	cephalosporin-C deacetylase activity
K1J60_RS41680	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K1J60_RS41700	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K1J60_RS41710	COG2890	protein-(glutamine-N5) methyltransferase activity
K1J60_RS41715	COG1902	pentaerythritol trinitrate reductase activity
K1J60_RS41715	COG0446	pyridine nucleotide-disulphide oxidoreductase
K1J60_RS41745	COG1461	Dihydroxyacetone kinase
K1J60_RS41750	COG2376	Dihydroxyacetone kinase
K1J60_RS41760	COG2267	carboxylic ester hydrolase activity
K1J60_RS41765	COG4106	trans-aconitate 2-methyltransferase activity
K1J60_RS41775	COG1132	(ABC) transporter
K1J60_RS41800	COG4585	Histidine kinase
K1J60_RS41805	COG2197	response regulator
K1J60_RS41820	COG2197	response regulator
K1J60_RS41835	COG2188	Transcriptional regulator
K1J60_RS41840	COG4214	carbohydrate transport
K1J60_RS41845	COG1129	ABC transporter
K1J60_RS41855	COG0179	Fumarylacetoacetate (FAA) hydrolase
K1J60_RS41860	COG4948	Mandelate Racemase Muconate Lactonizing
K1J60_RS41865	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS41885	COG1122	ATPase activity
K1J60_RS41895	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
K1J60_RS41900	COG0310	cobalt ion transport
K1J60_RS41905	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
K1J60_RS41925	COG0640	Transcriptional regulator
K1J60_RS41945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K1J60_RS41950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K1J60_RS41955	COG1120	ATPase activity
K1J60_RS41960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K1J60_RS41965	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K1J60_RS41975	COG2814	Major facilitator Superfamily
K1J60_RS41980	COG4264	IucA IucC family
K1J60_RS41985	COG0019	diaminopimelate decarboxylase activity
K1J60_RS42005	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS42030	COG3209	COG3209 Rhs family protein
K1J60_RS42045	COG2267	carboxylic ester hydrolase activity
K1J60_RS42060	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS42075	COG0202	RNA polymerase activity
K1J60_RS42080	COG2318	DinB family
K1J60_RS42105	COG0515	serine threonine protein kinase
K1J60_RS42105	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K1J60_RS42140	COG5002	protein histidine kinase activity
K1J60_RS42145	COG0745	RESPONSE REGULATOR receiver
K1J60_RS42225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K1J60_RS42230	COG0251	oxidation-reduction process
K1J60_RS42255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K1J60_RS42260	COG0251	oxidation-reduction process
K1J60_RS42270	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS42290	COG1132	(ABC) transporter
K1J60_RS42310	COG1902	pentaerythritol trinitrate reductase activity
K1J60_RS42330	COG1309	transcriptional regulator
K1J60_RS42335	COG0604	alcohol dehydrogenase
K1J60_RS42335	COG3321	synthase
K1J60_RS42350	COG1024	Enoyl-CoA hydratase
K1J60_RS42350	COG1250	3-hydroxyacyl-CoA dehydrogenase
K1J60_RS42400	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS42435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K1J60_RS42450	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS42475	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS42480	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
K1J60_RS42485	COG2814	Major facilitator Superfamily
K1J60_RS42500	COG1012	belongs to the aldehyde dehydrogenase family
K1J60_RS42505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K1J60_RS42510	COG0179	Fumarylacetoacetate (FAA) hydrolase
K1J60_RS42535	COG1063	alcohol dehydrogenase
K1J60_RS42540	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS42555	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
K1J60_RS42560	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
K1J60_RS42580	COG1269	ATP hydrolysis coupled proton transport
K1J60_RS42595	COG4109	DRTGG domain
K1J60_RS42630	COG0515	serine threonine protein kinase
K1J60_RS42640	COG2070	2-Nitropropane dioxygenase
K1J60_RS42655	COG2366	antibiotic biosynthetic process
K1J60_RS42660	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS42670	COG1024	Enoyl-CoA hydratase
K1J60_RS42765	COG0454	-acetyltransferase
K1J60_RS42765	COG0456	acetyltransferase
K1J60_RS42785	COG0640	Transcriptional regulator
K1J60_RS42805	COG1846	Transcriptional regulator
K1J60_RS42810	COG2409	Drug exporters of the RND superfamily
K1J60_RS42815	COG0583	DNA-binding transcription factor activity
K1J60_RS42830	COG0431	NADPH-dependent FMN reductase
K1J60_RS42840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K1J60_RS42865	COG0667	Aldo Keto reductase
K1J60_RS42875	COG0346	lactoylglutathione lyase activity
K1J60_RS42880	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K1J60_RS42885	COG1132	(ABC) transporter
K1J60_RS42920	COG0583	DNA-binding transcription factor activity
K1J60_RS42925	COG0667	Aldo Keto reductase
K1J60_RS42950	COG1131	(ABC) transporter
K1J60_RS42950	COG1716	ATPase activity
K1J60_RS42950	COG0842	Transport permease protein
K1J60_RS42965	COG0698	ribose 5-phosphate isomerase
K1J60_RS42990	COG1132	(ABC) transporter
K1J60_RS42995	COG1132	(ABC) transporter
K1J60_RS43000	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K1J60_RS43015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K1J60_RS43020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K1J60_RS43025	COG1120	ATPase activity
K1J60_RS43035	COG3486	L-lysine 6-monooxygenase (NADPH) activity
K1J60_RS43050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K1J60_RS43075	COG2318	DinB family
K1J60_RS43080	COG1396	sequence-specific DNA binding
K1J60_RS43085	COG0740	serine-type endopeptidase activity
K1J60_RS43090	COG0740	serine-type endopeptidase activity
K1J60_RS43125	COG0328	RNA-DNA hybrid ribonuclease activity
K1J60_RS43160	COG0494	nUDIX hydrolase
K1J60_RS43175	COG0477	Major facilitator Superfamily
K1J60_RS43180	COG0667	Aldo Keto reductase
K1J60_RS43200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K1J60_RS43265	COG2172	sigma factor antagonist activity
K1J60_RS43270	COG1366	Belongs to the anti-sigma-factor antagonist family
K1J60_RS43275	COG1366	Belongs to the anti-sigma-factor antagonist family
K1J60_RS43295	COG1191	sigma factor activity
K1J60_RS43325	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
K1J60_RS43335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K1J60_RS43345	COG2197	response regulator
K1J60_RS43350	COG4585	Histidine kinase
K1J60_RS43360	COG1131	(ABC) transporter
K1J60_RS43395	COG3903	Transcriptional regulator
K1J60_RS43395	COG3629	intracellular signal transduction
K1J60_RS43410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K1J60_RS43425	COG1017	nitric oxide dioxygenase activity
K1J60_RS43425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K1J60_RS43430	COG1959	2 iron, 2 sulfur cluster binding
K1J60_RS43445	COG0590	tRNA wobble adenosine to inosine editing
K1J60_RS43450	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS43475	COG0640	Transcriptional regulator
K1J60_RS43480	COG0346	lactoylglutathione lyase activity
K1J60_RS43495	COG1609	Transcriptional regulator
K1J60_RS43500	COG3507	Belongs to the glycosyl hydrolase 43 family
K1J60_RS43505	COG4172	Belongs to the ABC transporter superfamily
K1J60_RS43510	COG0444	Belongs to the ABC transporter superfamily
K1J60_RS43520	COG0747	negative chemotaxis
K1J60_RS43525	COG1609	Transcriptional regulator
K1J60_RS43535	COG3250	beta-galactosidase activity
K1J60_RS43540	COG1073	alpha beta
K1J60_RS43545	COG2814	Major facilitator Superfamily
K1J60_RS43550	COG1609	Transcriptional regulator
K1J60_RS43565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K1J60_RS43575	COG1609	Transcriptional regulator
K1J60_RS43580	COG1175	transmembrane transport
K1J60_RS43595	COG3250	beta-galactosidase activity
K1J60_RS43600	COG3250	beta-galactosidase activity
K1J60_RS43620	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K1J60_RS43630	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS43645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K1J60_RS43650	COG3401	FG-GAP repeat protein
K1J60_RS43665	COG1090	epimerase
K1J60_RS43690	COG1024	Enoyl-CoA hydratase
K1J60_RS43690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K1J60_RS43730	COG0375	protein maturation
K1J60_RS43735	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
K1J60_RS43740	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
K1J60_RS43745	COG0298	carbon dioxide binding
K1J60_RS43755	COG0309	Hydrogenase expression formation protein (HypE)
K1J60_RS43775	COG2205	protein histidine kinase activity
K1J60_RS43775	COG5002	protein histidine kinase activity
K1J60_RS43775	COG0784	Response regulator, receiver
K1J60_RS43805	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS43810	COG1309	transcriptional regulator
K1J60_RS43830	COG4249	Peptidase C14 caspase catalytic subunit p20
K1J60_RS43830	COG2319	Wd-40 repeat
K1J60_RS43840	COG3033	Beta-eliminating lyase
K1J60_RS43845	COG2226	methyltransferase
K1J60_RS43855	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
K1J60_RS43855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K1J60_RS43860	COG2186	Transcriptional regulator
K1J60_RS43885	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K1J60_RS43895	COG1414	Transcriptional regulator
K1J60_RS43900	COG4638	Rieske (2fe-2S)
K1J60_RS43905	COG2146	nitrite reductase [NAD(P)H] activity
K1J60_RS43920	COG2267	carboxylic ester hydrolase activity
K1J60_RS43940	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS43940	COG3321	synthase
K1J60_RS43940	COG0604	alcohol dehydrogenase
K1J60_RS43950	COG3971	2-oxopent-4-enoate hydratase activity
K1J60_RS43955	COG4569	acetaldehyde dehydrogenase (acetylating) activity
K1J60_RS43965	COG0477	Major facilitator Superfamily
K1J60_RS43975	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS43985	COG2223	nitrite transmembrane transporter activity
K1J60_RS44000	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K1J60_RS44005	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
K1J60_RS44015	COG0243	molybdopterin cofactor binding
K1J60_RS44020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K1J60_RS44025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K1J60_RS44025	COG2146	nitrite reductase [NAD(P)H] activity
K1J60_RS44070	COG0477	Major facilitator Superfamily
K1J60_RS44080	COG1960	acyl-CoA dehydrogenase activity
K1J60_RS44085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K1J60_RS44105	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K1J60_RS44105	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K1J60_RS44170	COG1024	Enoyl-CoA hydratase
K1J60_RS44175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K1J60_RS44190	COG0596	Alpha beta hydrolase
K1J60_RS44195	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS44225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K1J60_RS44230	COG2610	gluconate transmembrane transporter activity
K1J60_RS44235	COG4948	Mandelate Racemase Muconate Lactonizing
K1J60_RS44385	COG1595	DNA-templated transcription, initiation
K1J60_RS44615	COG0673	inositol 2-dehydrogenase activity
K1J60_RS44650	COG1192	Involved in chromosome partitioning
K1J60_RS44660	COG4106	trans-aconitate 2-methyltransferase activity
K1J60_RS44765	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS44790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K1J60_RS44815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K1J60_RS44815	COG3321	synthase
K1J60_RS44815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K1J60_RS44815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K1J60_RS44815	COG1028	Short-chain dehydrogenase reductase Sdr
K1J60_RS44880	COG2124	cytochrome p450
K1J60_RS45045	COG3321	synthase
K1J60_RS45045	COG0604	alcohol dehydrogenase
K1J60_RS45130	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
K1J60_RS45145	COG2226	methyltransferase
K1J60_RS45160	COG2124	cytochrome p450
K1J60_RS45170	COG0604	alcohol dehydrogenase
K1J60_RS45465	COG0142	geranyltranstransferase activity
K1J60_RS45550	COG0318	PFAM AMP-dependent synthetase and ligase
K1J60_RS45555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K1J60_RS45580	COG0587	DNA-directed DNA polymerase activity
K1J60_RS45605	COG1063	alcohol dehydrogenase
K1J60_RS45610	COG1063	alcohol dehydrogenase
K1J60_RS45665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K1J60_RS45855	COG1827	regulation of RNA biosynthetic process
K1J60_RS45990	COG0640	Transcriptional regulator
K1J60_RS46145	COG1819	glycosyl
K1J60_RS46225	COG3209	COG3209 Rhs family protein
K1J60_RS46350	COG2508	Transcriptional regulator
K1J60_RS46430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K1J60_RS46450	COG0494	nUDIX hydrolase
K1J60_RS46765	COG0494	nUDIX hydrolase