locus-tag	class	description
XNRR2_RS00045	COG1250	3-hydroxyacyl-CoA dehydrogenase
XNRR2_RS00050	COG3246	L-lysine catabolic process to acetate
XNRR2_RS00080	COG0477	Major facilitator Superfamily
XNRR2_RS00105	COG4335	DNA alkylation repair
XNRR2_RS00110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XNRR2_RS00110	COG0300	oxidoreductase activity
XNRR2_RS00110	COG3321	synthase
XNRR2_RS00110	COG4221	oxidoreductase activity
XNRR2_RS00135	COG1349	DNA-binding transcription factor activity
XNRR2_RS00145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XNRR2_RS00145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XNRR2_RS00145	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
XNRR2_RS00150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XNRR2_RS00150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XNRR2_RS00155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XNRR2_RS00215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XNRR2_RS00245	COG1695	Transcriptional regulator
XNRR2_RS00270	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS00285	COG0513	Belongs to the DEAD box helicase family
XNRR2_RS00295	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
XNRR2_RS00310	COG3217	Mosc domain protein beta barrel domain protein
XNRR2_RS00310	COG0633	Ferredoxin
XNRR2_RS00330	COG1349	DNA-binding transcription factor activity
XNRR2_RS00350	COG1940	carbohydrate kinase activity
XNRR2_RS00360	COG2223	nitrite transmembrane transporter activity
XNRR2_RS00375	COG2197	response regulator
XNRR2_RS00385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XNRR2_RS00390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XNRR2_RS00415	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
XNRR2_RS00455	COG0584	glycerophosphoryl diester phosphodiesterase
XNRR2_RS00470	COG1846	Transcriptional regulator
XNRR2_RS00490	COG0671	phosphoesterase, PA-phosphatase related
XNRR2_RS00520	COG2233	PERMEase
XNRR2_RS00525	COG0640	Transcriptional regulator
XNRR2_RS00530	COG1902	pentaerythritol trinitrate reductase activity
XNRR2_RS00545	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XNRR2_RS00560	COG2706	6-phosphogluconolactonase activity
XNRR2_RS00575	COG0071	Belongs to the small heat shock protein (HSP20) family
XNRR2_RS00580	COG0076	glutamate decarboxylase activity
XNRR2_RS00585	COG0243	molybdopterin cofactor binding
XNRR2_RS00600	COG0303	'Molybdopterin
XNRR2_RS00605	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XNRR2_RS00620	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XNRR2_RS00625	COG0583	DNA-binding transcription factor activity
XNRR2_RS00670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XNRR2_RS00675	COG1120	ATPase activity
XNRR2_RS00680	COG2207	Transcriptional regulator
XNRR2_RS00685	COG2814	Major facilitator Superfamily
XNRR2_RS00725	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
XNRR2_RS00745	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XNRR2_RS00765	COG0477	Major facilitator Superfamily
XNRR2_RS00770	COG1309	transcriptional regulator
XNRR2_RS00780	COG1472	Belongs to the glycosyl hydrolase 3 family
XNRR2_RS00790	COG1175	transmembrane transport
XNRR2_RS00800	COG1609	Transcriptional regulator
XNRR2_RS00805	COG0432	Pfam Uncharacterised protein family UPF0047
XNRR2_RS00810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XNRR2_RS00815	COG1116	anion transmembrane transporter activity
XNRR2_RS00825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XNRR2_RS00830	COG0492	ferredoxin-NADP+ reductase activity
XNRR2_RS00835	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XNRR2_RS00840	COG1132	(ABC) transporter
XNRR2_RS00860	COG1132	(ABC) transporter
XNRR2_RS00865	COG1132	(ABC) transporter
XNRR2_RS00880	COG1946	Acyl-CoA thioesterase
XNRR2_RS00895	COG2018	Roadblock/LC7 domain
XNRR2_RS00940	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XNRR2_RS00985	COG2124	cytochrome p450
XNRR2_RS00990	COG2130	NADP-dependent
XNRR2_RS00995	COG1233	COG1233 Phytoene dehydrogenase and related
XNRR2_RS01065	COG0477	Major facilitator Superfamily
XNRR2_RS01075	COG0583	DNA-binding transcription factor activity
XNRR2_RS01080	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XNRR2_RS01085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XNRR2_RS01090	COG1250	3-hydroxyacyl-CoA dehydrogenase
XNRR2_RS01095	COG1960	acyl-CoA dehydrogenase activity
XNRR2_RS01100	COG2391	methyltransferase activity
XNRR2_RS01145	COG0740	serine-type endopeptidase activity
XNRR2_RS01150	COG0740	serine-type endopeptidase activity
XNRR2_RS01185	COG4521	taurine ABC transporter
XNRR2_RS01190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XNRR2_RS01210	COG3959	Transketolase, thiamine diphosphate binding domain
XNRR2_RS01215	COG3958	Transketolase
XNRR2_RS01285	COG2755	lipolytic protein G-D-S-L family
XNRR2_RS01320	COG1657	PFAM Prenyltransferase squalene oxidase
XNRR2_RS01330	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
XNRR2_RS01340	COG1562	ergosterol biosynthetic process
XNRR2_RS01345	COG1134	teichoic acid transport
XNRR2_RS01345	COG1388	LysM domain
XNRR2_RS01370	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
XNRR2_RS01385	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
XNRR2_RS01400	COG1024	Enoyl-CoA hydratase
XNRR2_RS01415	COG2183	response to ionizing radiation
XNRR2_RS01430	COG1802	Transcriptional regulator
XNRR2_RS01435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XNRR2_RS01440	COG0402	S-adenosylhomocysteine deaminase activity
XNRR2_RS01465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XNRR2_RS01470	COG0789	Transcriptional regulator
XNRR2_RS01475	COG1024	Enoyl-CoA hydratase
XNRR2_RS01475	COG1250	3-hydroxyacyl-CoA dehydrogenase
XNRR2_RS01480	COG0183	Belongs to the thiolase family
XNRR2_RS01490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XNRR2_RS01495	COG1683	Conserved Protein
XNRR2_RS01500	COG1515	deoxyribonuclease V activity
XNRR2_RS01530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XNRR2_RS01540	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XNRR2_RS01540	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XNRR2_RS01550	COG0488	(ABC) transporter
XNRR2_RS01605	COG0254	rRNA binding
XNRR2_RS01625	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XNRR2_RS01670	COG1793	dna ligase
XNRR2_RS01675	COG1024	Enoyl-CoA hydratase
XNRR2_RS01710	COG0789	Transcriptional regulator
XNRR2_RS01755	COG1846	Transcriptional regulator
XNRR2_RS01815	COG1012	belongs to the aldehyde dehydrogenase family
XNRR2_RS01835	COG2814	Major facilitator Superfamily
XNRR2_RS01840	COG2259	Doxx family
XNRR2_RS01850	COG1869	D-ribose catabolic process
XNRR2_RS01855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XNRR2_RS01860	COG1172	Belongs to the binding-protein-dependent transport system permease family
XNRR2_RS01865	COG1129	ABC transporter
XNRR2_RS01870	COG1609	Transcriptional regulator
XNRR2_RS01890	COG1295	ribonuclease BN
XNRR2_RS01955	COG0673	inositol 2-dehydrogenase activity
XNRR2_RS01960	COG1879	ABC-type sugar transport system periplasmic component
XNRR2_RS01965	COG1172	Belongs to the binding-protein-dependent transport system permease family
XNRR2_RS01970	COG1129	ABC transporter
XNRR2_RS01975	COG1940	carbohydrate kinase activity
XNRR2_RS01980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XNRR2_RS01995	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XNRR2_RS02005	COG0583	DNA-binding transcription factor activity
XNRR2_RS02010	COG1115	amino acid carrier protein
XNRR2_RS02035	COG2154	pterin-4-alpha-carbinolamine dehydratase
XNRR2_RS02065	COG1140	nitrate reductase beta subunit
XNRR2_RS02125	COG0693	protein deglycase activity
XNRR2_RS02135	COG1597	lipid kinase activity
XNRR2_RS02140	COG4106	trans-aconitate 2-methyltransferase activity
XNRR2_RS02155	COG3226	Transcriptional regulator
XNRR2_RS02165	COG0604	alcohol dehydrogenase
XNRR2_RS02180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XNRR2_RS02200	COG1619	proteins homologs of microcin C7 resistance protein MccF
XNRR2_RS02210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XNRR2_RS02235	COG0596	Alpha beta hydrolase
XNRR2_RS02255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNRR2_RS02260	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNRR2_RS02265	COG1120	ATPase activity
XNRR2_RS02270	COG1250	3-hydroxyacyl-CoA dehydrogenase
XNRR2_RS02280	COG0604	alcohol dehydrogenase
XNRR2_RS02285	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XNRR2_RS02285	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XNRR2_RS02290	COG2301	Belongs to the HpcH HpaI aldolase family
XNRR2_RS02305	COG0688	phosphatidylethanolamine metabolic process
XNRR2_RS02315	COG1929	Belongs to the glycerate kinase type-1 family
XNRR2_RS02320	COG0488	(ABC) transporter
XNRR2_RS02330	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XNRR2_RS02335	COG0702	epimerase
XNRR2_RS02340	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS02350	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
XNRR2_RS02375	COG0159	tryptophan synthase activity
XNRR2_RS02390	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XNRR2_RS02405	COG0483	inositol monophosphate 1-phosphatase activity
XNRR2_RS02415	COG0095	Lipoate-protein ligase
XNRR2_RS02435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XNRR2_RS02460	COG0405	Gamma-glutamyltransferase
XNRR2_RS02490	COG0765	amino acid transport
XNRR2_RS02495	COG0765	amino acid transport
XNRR2_RS02500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XNRR2_RS02505	COG1126	abc transporter atp-binding protein
XNRR2_RS02535	COG1228	amidohydrolase
XNRR2_RS02540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XNRR2_RS02555	COG1960	acyl-CoA dehydrogenase activity
XNRR2_RS02585	COG2133	pyrroloquinoline quinone binding
XNRR2_RS02585	COG5183	chlorophyll binding
XNRR2_RS02590	COG1132	(ABC) transporter
XNRR2_RS02595	COG1132	(ABC) transporter
XNRR2_RS02600	COG1120	ATPase activity
XNRR2_RS02605	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNRR2_RS02610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNRR2_RS02615	COG2375	cellular response to nickel ion
XNRR2_RS02620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XNRR2_RS02625	COG2207	Transcriptional regulator
XNRR2_RS02655	COG2197	response regulator
XNRR2_RS02665	COG0464	growth
XNRR2_RS02745	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XNRR2_RS02755	COG1940	carbohydrate kinase activity
XNRR2_RS02765	COG1172	Belongs to the binding-protein-dependent transport system permease family
XNRR2_RS02775	COG2188	Transcriptional regulator
XNRR2_RS02780	COG0673	inositol 2-dehydrogenase activity
XNRR2_RS02795	COG2197	response regulator
XNRR2_RS02800	COG4585	Histidine kinase
XNRR2_RS02815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XNRR2_RS02820	COG1414	Transcriptional regulator
XNRR2_RS02835	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XNRR2_RS02840	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XNRR2_RS02845	COG2080	2 iron, 2 sulfur cluster binding
XNRR2_RS02865	COG0667	Aldo Keto reductase
XNRR2_RS02880	COG1960	acyl-CoA dehydrogenase activity
XNRR2_RS02890	COG0235	Class ii aldolase
XNRR2_RS02920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XNRR2_RS02930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XNRR2_RS02935	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS02960	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
XNRR2_RS02975	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS03000	COG1819	glycosyl
XNRR2_RS03005	COG2124	cytochrome p450
XNRR2_RS03015	COG0022	dehydrogenase e1 component
XNRR2_RS03020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XNRR2_RS03025	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XNRR2_RS03040	COG0656	L-ascorbic acid biosynthetic process
XNRR2_RS03050	COG2197	response regulator
XNRR2_RS03055	COG1309	transcriptional regulator
XNRR2_RS03070	COG4941	Belongs to the sigma-70 factor family
XNRR2_RS03075	COG3795	YCII-related domain
XNRR2_RS03080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XNRR2_RS03085	COG1621	beta-fructofuranosidase activity
XNRR2_RS03105	COG1609	Transcriptional regulator
XNRR2_RS03150	COG2233	PERMEase
XNRR2_RS03165	COG2351	hydroxyisourate hydrolase activity
XNRR2_RS03185	COG3622	Belongs to the hyi family
XNRR2_RS03190	COG2084	Dehydrogenase
XNRR2_RS03195	COG0753	catalase activity
XNRR2_RS03200	COG3960	tartronate-semialdehyde synthase activity
XNRR2_RS03210	COG0318	PFAM AMP-dependent synthetase and ligase
XNRR2_RS03215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XNRR2_RS03220	COG2197	response regulator
XNRR2_RS03230	COG1309	transcriptional regulator
XNRR2_RS03270	COG2252	PERMEase
XNRR2_RS03275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XNRR2_RS03290	COG3835	regulator
XNRR2_RS03295	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
XNRR2_RS03305	COG1802	Transcriptional regulator
XNRR2_RS03320	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS03335	COG0028	Belongs to the TPP enzyme family
XNRR2_RS03355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XNRR2_RS03360	COG1162	GTPase activity
XNRR2_RS03370	COG2365	Tyrosine phosphatase family
XNRR2_RS03410	COG1595	DNA-templated transcription, initiation
XNRR2_RS03420	COG0789	Transcriptional regulator
XNRR2_RS03430	COG0702	epimerase
XNRR2_RS03435	COG1846	Transcriptional regulator
XNRR2_RS03440	COG2409	Drug exporters of the RND superfamily
XNRR2_RS03450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNRR2_RS03455	COG1120	ATPase activity
XNRR2_RS03465	COG2255	four-way junction helicase activity
XNRR2_RS03490	COG2040	homocysteine
XNRR2_RS03510	COG1960	acyl-CoA dehydrogenase activity
XNRR2_RS03515	COG0604	alcohol dehydrogenase
XNRR2_RS03525	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XNRR2_RS03540	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XNRR2_RS03550	COG0175	sulfate reduction
XNRR2_RS03555	COG0529	Catalyzes the synthesis of activated sulfate
XNRR2_RS03580	COG1116	anion transmembrane transporter activity
XNRR2_RS03585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XNRR2_RS03600	COG0386	Belongs to the glutathione peroxidase family
XNRR2_RS03635	COG2176	DNA-directed DNA polymerase activity
XNRR2_RS03635	COG5002	protein histidine kinase activity
XNRR2_RS03700	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XNRR2_RS03705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XNRR2_RS03725	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
XNRR2_RS03730	COG1595	DNA-templated transcription, initiation
XNRR2_RS03745	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS03755	COG0726	polysaccharide deacetylase
XNRR2_RS03765	COG3220	belongs to the UPF0276 family
XNRR2_RS03790	COG0446	pyridine nucleotide-disulphide oxidoreductase
XNRR2_RS03795	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XNRR2_RS03815	COG0183	Belongs to the thiolase family
XNRR2_RS03820	COG1250	3-hydroxyacyl-CoA dehydrogenase
XNRR2_RS03820	COG1024	Enoyl-CoA hydratase
XNRR2_RS03840	COG0531	amino acid
XNRR2_RS03845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XNRR2_RS03850	COG4214	carbohydrate transport
XNRR2_RS03860	COG4213	ABC transporter substrate-binding protein
XNRR2_RS03870	COG0395	ABC-type sugar transport system, permease component
XNRR2_RS03875	COG1175	transmembrane transport
XNRR2_RS03880	COG1653	transport
XNRR2_RS03885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
XNRR2_RS03915	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XNRR2_RS03995	COG2235	arginine
XNRR2_RS04000	COG1320	monovalent cation:proton antiporter activity
XNRR2_RS04025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XNRR2_RS04025	COG2111	Na H antiporter
XNRR2_RS04035	COG2124	cytochrome p450
XNRR2_RS04065	COG0531	amino acid
XNRR2_RS04070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XNRR2_RS04075	COG2235	arginine
XNRR2_RS04095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XNRR2_RS04100	COG2890	protein-(glutamine-N5) methyltransferase activity
XNRR2_RS04130	COG1799	cell septum assembly
XNRR2_RS04140	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
XNRR2_RS04155	COG1556	Lactate utilization protein
XNRR2_RS04160	COG1139	Iron-sulfur cluster binding protein
XNRR2_RS04165	COG0247	lactate metabolic process
XNRR2_RS04170	COG1620	l-lactate permease
XNRR2_RS04180	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
XNRR2_RS04220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XNRR2_RS04230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XNRR2_RS04245	COG1120	ATPase activity
XNRR2_RS04250	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNRR2_RS04255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNRR2_RS04265	COG1733	regulation of RNA biosynthetic process
XNRR2_RS04285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XNRR2_RS04290	COG0601	transmembrane transport
XNRR2_RS04300	COG0747	negative chemotaxis
XNRR2_RS04310	COG1309	transcriptional regulator
XNRR2_RS04325	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XNRR2_RS04340	COG2936	dipeptidyl-peptidase activity
XNRR2_RS04360	COG3540	Alkaline phosphatase
XNRR2_RS04370	COG2050	protein possibly involved in aromatic compounds catabolism
XNRR2_RS04385	COG0789	Transcriptional regulator
XNRR2_RS04390	COG0640	Transcriptional regulator
XNRR2_RS04410	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XNRR2_RS04455	COG0438	transferase activity, transferring glycosyl groups
XNRR2_RS04460	COG3226	Transcriptional regulator
XNRR2_RS04465	COG0738	Major facilitator superfamily
XNRR2_RS04480	COG4213	ABC transporter substrate-binding protein
XNRR2_RS04485	COG1172	Belongs to the binding-protein-dependent transport system permease family
XNRR2_RS04490	COG1172	Belongs to the binding-protein-dependent transport system permease family
XNRR2_RS04495	COG1129	ABC transporter
XNRR2_RS04500	COG1846	Transcriptional regulator
XNRR2_RS04500	COG1940	carbohydrate kinase activity
XNRR2_RS04505	COG0252	asparaginase activity
XNRR2_RS04515	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS04535	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS04550	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS04585	COG0473	3-isopropylmalate dehydrogenase activity
XNRR2_RS04600	COG0656	L-ascorbic acid biosynthetic process
XNRR2_RS04635	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XNRR2_RS04660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XNRR2_RS04670	COG1127	ABC transporter
XNRR2_RS04710	COG0583	DNA-binding transcription factor activity
XNRR2_RS04720	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
XNRR2_RS04735	COG4221	oxidoreductase activity
XNRR2_RS04740	COG0300	oxidoreductase activity
XNRR2_RS04795	COG2233	PERMEase
XNRR2_RS04800	COG0402	S-adenosylhomocysteine deaminase activity
XNRR2_RS04815	COG0559	Belongs to the binding-protein-dependent transport system permease family
XNRR2_RS04850	COG0395	ABC-type sugar transport system, permease component
XNRR2_RS04855	COG1063	alcohol dehydrogenase
XNRR2_RS04870	COG0438	transferase activity, transferring glycosyl groups
XNRR2_RS04875	COG2197	response regulator
XNRR2_RS04885	COG1136	(ABC) transporter
XNRR2_RS04895	COG2197	response regulator
XNRR2_RS04905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XNRR2_RS04915	COG3251	PFAM MbtH domain protein
XNRR2_RS04925	COG2175	clavaminate synthase activity
XNRR2_RS04955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XNRR2_RS04960	COG0531	amino acid
XNRR2_RS04965	COG0569	domain protein
XNRR2_RS04995	COG1136	(ABC) transporter
XNRR2_RS05015	COG0756	dUTP diphosphatase activity
XNRR2_RS05040	COG2205	protein histidine kinase activity
XNRR2_RS05045	COG0745	RESPONSE REGULATOR receiver
XNRR2_RS05055	COG0483	inositol monophosphate 1-phosphatase activity
XNRR2_RS05110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XNRR2_RS05115	COG1802	Transcriptional regulator
XNRR2_RS05130	COG0612	Peptidase, M16
XNRR2_RS05135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
XNRR2_RS05145	COG0366	Alpha amylase catalytic
XNRR2_RS05150	COG0395	ABC-type sugar transport system, permease component
XNRR2_RS05155	COG1175	transmembrane transport
XNRR2_RS05160	COG1653	transport
XNRR2_RS05175	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XNRR2_RS05210	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XNRR2_RS05215	COG1802	Transcriptional regulator
XNRR2_RS05250	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
XNRR2_RS05265	COG0588	phosphoglycerate mutase activity
XNRR2_RS05285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XNRR2_RS05290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XNRR2_RS05335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XNRR2_RS05345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XNRR2_RS05350	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XNRR2_RS05360	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XNRR2_RS05380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XNRR2_RS05390	COG2205	protein histidine kinase activity
XNRR2_RS05395	COG0745	RESPONSE REGULATOR receiver
XNRR2_RS05400	COG1126	abc transporter atp-binding protein
XNRR2_RS05405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XNRR2_RS05410	COG0765	amino acid transport
XNRR2_RS05415	COG0765	amino acid transport
XNRR2_RS05420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XNRR2_RS05435	COG2137	regulation of response to DNA damage stimulus
XNRR2_RS05440	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XNRR2_RS05465	COG0628	permease
XNRR2_RS05490	COG1201	RNA secondary structure unwinding
XNRR2_RS05495	COG0596	Alpha beta hydrolase
XNRR2_RS05515	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XNRR2_RS05525	COG0783	Belongs to the Dps family
XNRR2_RS05530	COG1396	sequence-specific DNA binding
XNRR2_RS05535	COG1546	Belongs to the CinA family
XNRR2_RS05535	COG1058	Belongs to the CinA family
XNRR2_RS05545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XNRR2_RS05555	COG1674	ftsk spoiiie
XNRR2_RS05565	COG2205	protein histidine kinase activity
XNRR2_RS05565	COG3437	response regulator, receiver
XNRR2_RS05565	COG3850	Histidine kinase
XNRR2_RS05565	COG4999	Histidine kinase
XNRR2_RS05570	COG2770	Histidine kinase
XNRR2_RS05570	COG2208	phosphoserine phosphatase activity
XNRR2_RS05600	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
XNRR2_RS05605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XNRR2_RS05610	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
XNRR2_RS05630	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XNRR2_RS05635	COG0612	Peptidase, M16
XNRR2_RS05640	COG1185	polyribonucleotide nucleotidyltransferase activity
XNRR2_RS05645	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XNRR2_RS05655	COG0455	bacterial-type flagellum organization
XNRR2_RS05660	COG0747	negative chemotaxis
XNRR2_RS05665	COG0601	transmembrane transport
XNRR2_RS05670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XNRR2_RS05675	COG0444	Belongs to the ABC transporter superfamily
XNRR2_RS05680	COG4608	Belongs to the ABC transporter superfamily
XNRR2_RS05685	COG1357	PFAM Pentapeptide repeats (8 copies)
XNRR2_RS05700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XNRR2_RS05705	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XNRR2_RS05715	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XNRR2_RS05730	COG0779	Required for maturation of 30S ribosomal subunits
XNRR2_RS05750	COG0442	prolyl-tRNA aminoacylation
XNRR2_RS05775	COG0601	transmembrane transport
XNRR2_RS05780	COG0747	negative chemotaxis
XNRR2_RS05795	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XNRR2_RS05800	COG0750	zinc metalloprotease
XNRR2_RS05805	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XNRR2_RS05810	COG1940	carbohydrate kinase activity
XNRR2_RS05815	COG1012	belongs to the aldehyde dehydrogenase family
XNRR2_RS05820	COG2508	Transcriptional regulator
XNRR2_RS05850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XNRR2_RS05855	COG1177	transmembrane transport
XNRR2_RS05860	COG1176	ABC-type spermidine putrescine transport system, permease component I
XNRR2_RS05865	COG3842	ATPase activity
XNRR2_RS05875	COG1012	belongs to the aldehyde dehydrogenase family
XNRR2_RS05890	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
XNRR2_RS05910	COG1012	belongs to the aldehyde dehydrogenase family
XNRR2_RS05920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XNRR2_RS05945	COG3842	ATPase activity
XNRR2_RS05950	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XNRR2_RS05960	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XNRR2_RS05965	COG0575	Belongs to the CDS family
XNRR2_RS05970	COG0233	cytoplasmic translational termination
XNRR2_RS05975	COG0528	UMP kinase activity
XNRR2_RS05980	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XNRR2_RS05985	COG0052	Belongs to the universal ribosomal protein uS2 family
XNRR2_RS06000	COG1191	sigma factor activity
XNRR2_RS06015	COG0792	nuclease activity
XNRR2_RS06030	COG0681	Belongs to the peptidase S26 family
XNRR2_RS06035	COG0681	Belongs to the peptidase S26 family
XNRR2_RS06040	COG0681	Belongs to the peptidase S26 family
XNRR2_RS06045	COG0681	Belongs to the peptidase S26 family
XNRR2_RS06050	COG0335	large ribosomal subunit rRNA binding
XNRR2_RS06055	COG0336	Belongs to the RNA methyltransferase TrmD family
XNRR2_RS06060	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XNRR2_RS06065	COG1837	Belongs to the UPF0109 family
XNRR2_RS06070	COG0228	four-way junction DNA binding
XNRR2_RS06085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XNRR2_RS06095	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XNRR2_RS06125	COG0477	Major facilitator Superfamily
XNRR2_RS06130	COG1196	nuclear chromosome segregation
XNRR2_RS06140	COG1254	Belongs to the acylphosphatase family
XNRR2_RS06145	COG2340	Cysteine-rich secretory protein family
XNRR2_RS06150	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XNRR2_RS06155	COG0571	ribonuclease III activity
XNRR2_RS06160	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XNRR2_RS06175	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XNRR2_RS06180	COG0742	ribosomal rna small subunit methyltransferase
XNRR2_RS06190	COG1461	Dihydroxyacetone kinase
XNRR2_RS06195	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XNRR2_RS06200	COG0351	phosphomethylpyrimidine kinase
XNRR2_RS06220	COG1181	Belongs to the D-alanine--D-alanine ligase family
XNRR2_RS06225	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XNRR2_RS06235	COG1920	GTP binding
XNRR2_RS06245	COG0776	regulation of translation
XNRR2_RS06255	COG0066	3-isopropylmalate dehydratase activity
XNRR2_RS06260	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XNRR2_RS06265	COG1414	Transcriptional regulator
XNRR2_RS06310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XNRR2_RS06315	COG0179	Fumarylacetoacetate (FAA) hydrolase
XNRR2_RS06330	COG2018	Roadblock/LC7 domain
XNRR2_RS06350	COG2018	Roadblock/LC7 domain
XNRR2_RS06370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XNRR2_RS06380	COG2353	YceI-like domain
XNRR2_RS06420	COG0789	Transcriptional regulator
XNRR2_RS06440	COG4221	oxidoreductase activity
XNRR2_RS06475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XNRR2_RS06480	COG0477	Major facilitator Superfamily
XNRR2_RS06485	COG2957	Belongs to the agmatine deiminase family
XNRR2_RS06490	COG0804	urea catabolic process
XNRR2_RS06495	COG0832	Belongs to the urease beta subunit family
XNRR2_RS06495	COG0831	urea catabolic process
XNRR2_RS06500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XNRR2_RS06505	COG0473	3-isopropylmalate dehydrogenase activity
XNRR2_RS06530	COG1012	belongs to the aldehyde dehydrogenase family
XNRR2_RS06535	COG0506	proline dehydrogenase activity
XNRR2_RS06540	COG3835	regulator
XNRR2_RS06560	COG2890	protein-(glutamine-N5) methyltransferase activity
XNRR2_RS06570	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XNRR2_RS06575	COG0440	acetolactate synthase activity
XNRR2_RS06595	COG0667	Aldo Keto reductase
XNRR2_RS06600	COG2133	pyrroloquinoline quinone binding
XNRR2_RS06620	COG2197	response regulator
XNRR2_RS06640	COG2409	Drug exporters of the RND superfamily
XNRR2_RS06645	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XNRR2_RS06655	COG0154	amidase activity
XNRR2_RS06660	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XNRR2_RS06670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XNRR2_RS06680	COG4221	oxidoreductase activity
XNRR2_RS06700	COG0482	sulfurtransferase activity
XNRR2_RS06725	COG2860	membrane
XNRR2_RS06730	COG4608	Belongs to the ABC transporter superfamily
XNRR2_RS06735	COG0444	Belongs to the ABC transporter superfamily
XNRR2_RS06750	COG0747	negative chemotaxis
XNRR2_RS06770	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XNRR2_RS06775	COG0509	glycine decarboxylation via glycine cleavage system
XNRR2_RS06780	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XNRR2_RS06785	COG1760	l-serine dehydratase
XNRR2_RS06800	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XNRR2_RS06805	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XNRR2_RS06810	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XNRR2_RS06825	COG0477	Major facilitator Superfamily
XNRR2_RS06840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XNRR2_RS06865	COG2085	NADP oxidoreductase coenzyme F420-dependent
XNRR2_RS06890	COG1376	ErfK ybiS ycfS ynhG family protein
XNRR2_RS06915	COG1132	(ABC) transporter
XNRR2_RS06920	COG1132	(ABC) transporter
XNRR2_RS06930	COG1733	regulation of RNA biosynthetic process
XNRR2_RS06950	COG0366	Alpha amylase catalytic
XNRR2_RS06955	COG0366	Alpha amylase catalytic
XNRR2_RS06960	COG3281	Trehalose synthase
XNRR2_RS06965	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XNRR2_RS06980	COG1119	ATPase activity
XNRR2_RS06985	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XNRR2_RS07000	COG1301	dicarboxylic acid transport
XNRR2_RS07005	COG3290	protein histidine kinase activity
XNRR2_RS07010	COG4565	transcriptional regulatory protein
XNRR2_RS07015	COG0205	6-phosphofructokinase activity
XNRR2_RS07020	COG0280	phosphate acetyltransferase
XNRR2_RS07020	COG0857	belongs to the CobB CobQ family
XNRR2_RS07025	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
XNRR2_RS07065	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XNRR2_RS07065	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XNRR2_RS07140	COG1335	isochorismatase
XNRR2_RS07170	COG0183	Belongs to the thiolase family
XNRR2_RS07190	COG1131	(ABC) transporter
XNRR2_RS07225	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
XNRR2_RS07240	COG1250	3-hydroxyacyl-CoA dehydrogenase
XNRR2_RS07255	COG4585	Histidine kinase
XNRR2_RS07260	COG2197	response regulator
XNRR2_RS07280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XNRR2_RS07285	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XNRR2_RS07290	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XNRR2_RS07295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XNRR2_RS07300	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XNRR2_RS07305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XNRR2_RS07310	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XNRR2_RS07325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XNRR2_RS07330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XNRR2_RS07340	COG2890	protein-(glutamine-N5) methyltransferase activity
XNRR2_RS07345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XNRR2_RS07350	COG0254	rRNA binding
XNRR2_RS07355	COG1316	TRANSCRIPTIONal
XNRR2_RS07365	COG0083	homoserine kinase activity
XNRR2_RS07370	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XNRR2_RS07375	COG0460	homoserine dehydrogenase
XNRR2_RS07380	COG0019	diaminopimelate decarboxylase activity
XNRR2_RS07385	COG0018	arginyl-trna synthetase
XNRR2_RS07410	COG1012	belongs to the aldehyde dehydrogenase family
XNRR2_RS07420	COG1191	sigma factor activity
XNRR2_RS07425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XNRR2_RS07425	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XNRR2_RS07435	COG2267	carboxylic ester hydrolase activity
XNRR2_RS07440	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
XNRR2_RS07455	COG0772	Belongs to the SEDS family
XNRR2_RS07530	COG0726	polysaccharide deacetylase
XNRR2_RS07535	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XNRR2_RS07540	COG0477	Major facilitator Superfamily
XNRR2_RS07555	COG1595	DNA-templated transcription, initiation
XNRR2_RS07565	COG1131	(ABC) transporter
XNRR2_RS07585	COG0745	RESPONSE REGULATOR receiver
XNRR2_RS07590	COG2205	protein histidine kinase activity
XNRR2_RS07595	COG0508	dehydrogenase complex catalyzes the overall conversion of
XNRR2_RS07595	COG0567	Dehydrogenase, E1 component
XNRR2_RS07625	COG2255	four-way junction helicase activity
XNRR2_RS07670	COG0604	alcohol dehydrogenase
XNRR2_RS07675	COG0281	malic enzyme
XNRR2_RS07690	COG1126	abc transporter atp-binding protein
XNRR2_RS07695	COG4106	trans-aconitate 2-methyltransferase activity
XNRR2_RS07755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XNRR2_RS07760	COG1959	2 iron, 2 sulfur cluster binding
XNRR2_RS07780	COG2515	1-aminocyclopropane-1-carboxylate deaminase
XNRR2_RS07795	COG2172	sigma factor antagonist activity
XNRR2_RS07810	COG1597	lipid kinase activity
XNRR2_RS07830	COG0363	glucosamine-6-phosphate deaminase activity
XNRR2_RS07835	COG1472	Belongs to the glycosyl hydrolase 3 family
XNRR2_RS07840	COG0395	ABC-type sugar transport system, permease component
XNRR2_RS07845	COG1175	transmembrane transport
XNRR2_RS07850	COG2182	Extracellular solute-binding protein
XNRR2_RS07855	COG2188	Transcriptional regulator
XNRR2_RS07860	COG1966	Carbon starvation protein
XNRR2_RS07880	COG2124	cytochrome p450
XNRR2_RS07890	COG0242	peptide deformylase activity
XNRR2_RS07900	COG5662	AntiSigma factor
XNRR2_RS07905	COG1595	DNA-templated transcription, initiation
XNRR2_RS07915	COG2135	peptidase activity
XNRR2_RS07925	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XNRR2_RS07935	COG2076	Multidrug Resistance protein
XNRR2_RS07945	COG0483	inositol monophosphate 1-phosphatase activity
XNRR2_RS07950	COG0753	catalase activity
XNRR2_RS07975	COG1615	UPF0182 protein
XNRR2_RS07985	COG3480	Lon protease (S16) C-terminal proteolytic domain
XNRR2_RS08040	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XNRR2_RS08075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XNRR2_RS08080	COG0210	DNA helicase
XNRR2_RS08170	COG0513	Belongs to the DEAD box helicase family
XNRR2_RS08180	COG1432	Conserved Protein
XNRR2_RS08190	COG2095	MarC family integral membrane protein
XNRR2_RS08195	COG0613	PHP domain protein
XNRR2_RS08200	COG2814	Major facilitator Superfamily
XNRR2_RS08210	COG0598	Magnesium transport protein CorA
XNRR2_RS08250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XNRR2_RS08255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XNRR2_RS08265	COG1595	DNA-templated transcription, initiation
XNRR2_RS08280	COG1024	Enoyl-CoA hydratase
XNRR2_RS08290	COG0519	Catalyzes the synthesis of GMP from XMP
XNRR2_RS08325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XNRR2_RS08355	COG0456	acetyltransferase
XNRR2_RS08360	COG2912	Transglutaminase-like superfamily
XNRR2_RS08370	COG1609	Transcriptional regulator
XNRR2_RS08375	COG1172	Belongs to the binding-protein-dependent transport system permease family
XNRR2_RS08385	COG1129	ABC transporter
XNRR2_RS08390	COG1879	ABC-type sugar transport system periplasmic component
XNRR2_RS08395	COG3250	beta-galactosidase activity
XNRR2_RS08415	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
XNRR2_RS08440	COG4608	Belongs to the ABC transporter superfamily
XNRR2_RS08450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XNRR2_RS08455	COG0601	transmembrane transport
XNRR2_RS08465	COG4608	Belongs to the ABC transporter superfamily
XNRR2_RS08470	COG0444	Belongs to the ABC transporter superfamily
XNRR2_RS08475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XNRR2_RS08480	COG0601	transmembrane transport
XNRR2_RS08545	COG1554	hydrolase, family 65, central catalytic
XNRR2_RS08605	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS08610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XNRR2_RS08620	COG3473	Maleate cis-trans isomerase
XNRR2_RS08640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XNRR2_RS08645	COG0765	amino acid transport
XNRR2_RS08650	COG0765	amino acid transport
XNRR2_RS08655	COG1126	abc transporter atp-binding protein
XNRR2_RS08685	COG3397	chitin binding
XNRR2_RS08740	COG0673	inositol 2-dehydrogenase activity
XNRR2_RS08745	COG0179	Fumarylacetoacetate (FAA) hydrolase
XNRR2_RS08750	COG0706	membrane insertase activity
XNRR2_RS08795	COG2271	Major facilitator Superfamily
XNRR2_RS08805	COG2733	membrane
XNRR2_RS08835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XNRR2_RS08845	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XNRR2_RS08870	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XNRR2_RS08880	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XNRR2_RS08885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XNRR2_RS08890	COG1263	PTS System
XNRR2_RS08900	COG1234	tRNA 3'-trailer cleavage
XNRR2_RS08925	COG1113	amino acid transport
XNRR2_RS08940	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XNRR2_RS08950	COG1335	isochorismatase
XNRR2_RS08980	COG0277	FAD linked oxidase domain protein
XNRR2_RS08990	COG3185	4-Hydroxyphenylpyruvate dioxygenase
XNRR2_RS09000	COG1174	glycine betaine transport
XNRR2_RS09005	COG1125	glycine betaine transport
XNRR2_RS09005	COG0517	IMP dehydrogenase activity
XNRR2_RS09010	COG1174	glycine betaine transport
XNRR2_RS09055	COG1116	anion transmembrane transporter activity
XNRR2_RS09095	COG2318	DinB family
XNRR2_RS09125	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XNRR2_RS09150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XNRR2_RS09165	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XNRR2_RS09170	COG0395	ABC-type sugar transport system, permease component
XNRR2_RS09175	COG1175	transmembrane transport
XNRR2_RS09190	COG1678	Uncharacterized ACR, COG1678
XNRR2_RS09195	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XNRR2_RS09200	COG0776	regulation of translation
XNRR2_RS09210	COG3973	AAA domain
XNRR2_RS09210	COG3973	AAA domain
XNRR2_RS09255	COG0583	DNA-binding transcription factor activity
XNRR2_RS09270	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XNRR2_RS09275	COG0793	Belongs to the peptidase S41A family
XNRR2_RS09285	COG2884	Cell division ATP-binding protein ftsE
XNRR2_RS09300	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XNRR2_RS09305	COG0515	serine threonine protein kinase
XNRR2_RS09310	COG0515	serine threonine protein kinase
XNRR2_RS09315	COG1716	ATPase activity
XNRR2_RS09335	COG0395	ABC-type sugar transport system, permease component
XNRR2_RS09340	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
XNRR2_RS09345	COG0438	transferase activity, transferring glycosyl groups
XNRR2_RS09350	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
XNRR2_RS09355	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
XNRR2_RS09365	COG2226	methyltransferase
XNRR2_RS09380	COG2902	Dehydrogenase
XNRR2_RS09400	COG0583	DNA-binding transcription factor activity
XNRR2_RS09420	COG0653	protein targeting
XNRR2_RS09425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XNRR2_RS09430	COG3214	Protein conserved in bacteria
XNRR2_RS09435	COG2197	response regulator
XNRR2_RS09440	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
XNRR2_RS09450	COG0823	Involved in the tonB-independent uptake of proteins
XNRR2_RS09455	COG5002	protein histidine kinase activity
XNRR2_RS09460	COG0745	RESPONSE REGULATOR receiver
XNRR2_RS09465	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XNRR2_RS09485	COG0714	Associated with various cellular activities
XNRR2_RS09490	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
XNRR2_RS09525	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XNRR2_RS09535	COG1482	cell wall glycoprotein biosynthetic process
XNRR2_RS09545	COG2835	tetraacyldisaccharide 4'-kinase activity
XNRR2_RS09555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XNRR2_RS09565	COG1620	l-lactate permease
XNRR2_RS09600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
XNRR2_RS09605	COG0778	Nitroreductase
XNRR2_RS09605	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
XNRR2_RS09635	COG1316	TRANSCRIPTIONal
XNRR2_RS09655	COG1316	TRANSCRIPTIONal
XNRR2_RS09660	COG3046	protein related to deoxyribodipyrimidine photolyase
XNRR2_RS09710	COG0753	catalase activity
XNRR2_RS09745	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
XNRR2_RS09755	COG2072	flavoprotein involved in K transport
XNRR2_RS09780	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
XNRR2_RS09795	COG2205	protein histidine kinase activity
XNRR2_RS09800	COG0745	RESPONSE REGULATOR receiver
XNRR2_RS09805	COG3104	oligopeptide transport
XNRR2_RS09815	COG1366	Belongs to the anti-sigma-factor antagonist family
XNRR2_RS09820	COG1191	sigma factor activity
XNRR2_RS09825	COG1228	amidohydrolase
XNRR2_RS09835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XNRR2_RS09855	COG0395	ABC-type sugar transport system, permease component
XNRR2_RS09915	COG2755	lipolytic protein G-D-S-L family
XNRR2_RS09920	COG0183	Belongs to the thiolase family
XNRR2_RS09940	COG1476	TRANSCRIPTIONal
XNRR2_RS09955	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
XNRR2_RS09965	COG1136	(ABC) transporter
XNRR2_RS09970	COG1136	(ABC) transporter
XNRR2_RS09970	COG0577	efflux transmembrane transporter activity
XNRR2_RS09975	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XNRR2_RS09980	COG1252	NADH dehydrogenase
XNRR2_RS10010	COG0148	phosphopyruvate hydratase activity
XNRR2_RS10025	COG2124	cytochrome p450
XNRR2_RS10065	COG1733	regulation of RNA biosynthetic process
XNRR2_RS10105	COG0154	amidase activity
XNRR2_RS10110	COG3226	Transcriptional regulator
XNRR2_RS10120	COG1473	amidohydrolase
XNRR2_RS10175	COG3629	intracellular signal transduction
XNRR2_RS10175	COG3903	Transcriptional regulator
XNRR2_RS10185	COG0477	Major facilitator Superfamily
XNRR2_RS10225	COG0596	Alpha beta hydrolase
XNRR2_RS10235	COG1316	TRANSCRIPTIONal
XNRR2_RS10255	COG0789	Transcriptional regulator
XNRR2_RS10280	COG4585	Histidine kinase
XNRR2_RS10290	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XNRR2_RS10295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XNRR2_RS10320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XNRR2_RS10325	COG0193	aminoacyl-tRNA hydrolase activity
XNRR2_RS10335	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XNRR2_RS10355	COG4106	trans-aconitate 2-methyltransferase activity
XNRR2_RS10365	COG2197	response regulator
XNRR2_RS10370	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
XNRR2_RS10415	COG0488	(ABC) transporter
XNRR2_RS10420	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XNRR2_RS10425	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XNRR2_RS10430	COG0084	hydrolase, TatD family'
XNRR2_RS10520	COG2409	Drug exporters of the RND superfamily
XNRR2_RS10530	COG4946	Tricorn protease homolog
XNRR2_RS10530	COG0793	Belongs to the peptidase S41A family
XNRR2_RS10540	COG4221	oxidoreductase activity
XNRR2_RS10550	COG2072	flavoprotein involved in K transport
XNRR2_RS10560	COG0708	Exodeoxyribonuclease III
XNRR2_RS10570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XNRR2_RS10590	COG2197	response regulator
XNRR2_RS10630	COG0315	cyclic pyranopterin monophosphate synthase activity
XNRR2_RS10630	COG0521	Mo-molybdopterin cofactor biosynthetic process
XNRR2_RS10635	COG0315	cyclic pyranopterin monophosphate synthase activity
XNRR2_RS10645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XNRR2_RS10650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XNRR2_RS10660	COG3263	regulation of cellular component size
XNRR2_RS10675	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XNRR2_RS10685	COG1970	mechanosensitive ion channel activity
XNRR2_RS10700	COG3191	aminopeptidase activity
XNRR2_RS10720	COG3384	dioxygenase
XNRR2_RS10725	COG1846	Transcriptional regulator
XNRR2_RS10780	COG2050	protein possibly involved in aromatic compounds catabolism
XNRR2_RS10790	COG0183	Belongs to the thiolase family
XNRR2_RS10795	COG1024	Enoyl-CoA hydratase
XNRR2_RS10800	COG1250	3-hydroxyacyl-CoA dehydrogenase
XNRR2_RS10805	COG3396	Phenylacetate-CoA oxygenase
XNRR2_RS10810	COG3460	Phenylacetate-CoA oxygenase
XNRR2_RS10815	COG3396	Phenylacetate-CoA oxygenase
XNRR2_RS10820	COG2151	metal-sulfur cluster biosynthetic enzyme
XNRR2_RS10825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XNRR2_RS10890	COG0582	viral genome integration into host DNA
XNRR2_RS10935	COG1609	Transcriptional regulator
XNRR2_RS11005	COG1278	Cold shock
XNRR2_RS11085	COG5297	Belongs to the glycosyl hydrolase family 6
XNRR2_RS11105	COG0148	phosphopyruvate hydratase activity
XNRR2_RS11120	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
XNRR2_RS11150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XNRR2_RS11190	COG0515	serine threonine protein kinase
XNRR2_RS11190	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XNRR2_RS11195	COG1309	transcriptional regulator
XNRR2_RS11215	COG2072	flavoprotein involved in K transport
XNRR2_RS11225	COG2271	Major facilitator Superfamily
XNRR2_RS11245	COG1366	Belongs to the anti-sigma-factor antagonist family
XNRR2_RS11325	COG4821	SIS domain
XNRR2_RS11335	COG0259	pyridoxamine-phosphate oxidase activity
XNRR2_RS11355	COG1024	Enoyl-CoA hydratase
XNRR2_RS11370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XNRR2_RS11405	COG0583	DNA-binding transcription factor activity
XNRR2_RS11415	COG0247	lactate metabolic process
XNRR2_RS11415	COG0277	FAD linked oxidase domain protein
XNRR2_RS11420	COG2205	protein histidine kinase activity
XNRR2_RS11440	COG2124	cytochrome p450
XNRR2_RS11450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XNRR2_RS11545	COG0667	Aldo Keto reductase
XNRR2_RS11570	COG2252	PERMEase
XNRR2_RS11580	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
XNRR2_RS11605	COG2814	Major facilitator Superfamily
XNRR2_RS11615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
XNRR2_RS11620	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
XNRR2_RS11625	COG1278	Cold shock
XNRR2_RS11635	COG2197	response regulator
XNRR2_RS11640	COG1132	(ABC) transporter
XNRR2_RS11645	COG1132	(ABC) transporter
XNRR2_RS11655	COG0515	serine threonine protein kinase
XNRR2_RS11660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XNRR2_RS11665	COG1120	ATPase activity
XNRR2_RS11670	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNRR2_RS11675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNRR2_RS11685	COG1295	ribonuclease BN
XNRR2_RS11695	COG2124	cytochrome p450
XNRR2_RS11750	COG1061	Type III restriction enzyme res subunit
XNRR2_RS11780	COG0667	Aldo Keto reductase
XNRR2_RS11785	COG0789	Transcriptional regulator
XNRR2_RS11810	COG3973	AAA domain
XNRR2_RS11855	COG4585	Histidine kinase
XNRR2_RS11860	COG2197	response regulator
XNRR2_RS11895	COG0406	alpha-ribazole phosphatase activity
XNRR2_RS11905	COG1737	Transcriptional regulator
XNRR2_RS11910	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
XNRR2_RS11915	COG1263	PTS System
XNRR2_RS11915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XNRR2_RS11920	COG0667	Aldo Keto reductase
XNRR2_RS11960	COG1278	Cold shock
XNRR2_RS11975	COG0463	Glycosyl transferase, family 2
XNRR2_RS12000	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XNRR2_RS12040	COG1105	Belongs to the carbohydrate kinase PfkB family
XNRR2_RS12065	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XNRR2_RS12095	COG1309	transcriptional regulator
XNRR2_RS12110	COG0577	efflux transmembrane transporter activity
XNRR2_RS12110	COG1136	(ABC) transporter
XNRR2_RS12145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XNRR2_RS12210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XNRR2_RS12280	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
XNRR2_RS12295	COG1366	Belongs to the anti-sigma-factor antagonist family
XNRR2_RS12300	COG1366	Belongs to the anti-sigma-factor antagonist family
XNRR2_RS12305	COG2172	sigma factor antagonist activity
XNRR2_RS12330	COG1136	(ABC) transporter
XNRR2_RS12330	COG0577	efflux transmembrane transporter activity
XNRR2_RS12335	COG0577	efflux transmembrane transporter activity
XNRR2_RS12395	COG4585	Histidine kinase
XNRR2_RS12400	COG2197	response regulator
XNRR2_RS12405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XNRR2_RS12410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XNRR2_RS12430	COG0301	tRNA thio-modification
XNRR2_RS12455	COG0513	Belongs to the DEAD box helicase family
XNRR2_RS12460	COG1278	Cold shock
XNRR2_RS12490	COG2208	phosphoserine phosphatase activity
XNRR2_RS12490	COG2770	Histidine kinase
XNRR2_RS12525	COG0456	acetyltransferase
XNRR2_RS12535	COG0436	Aminotransferase
XNRR2_RS12545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XNRR2_RS12555	COG3486	L-lysine 6-monooxygenase (NADPH) activity
XNRR2_RS12565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XNRR2_RS12565	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XNRR2_RS12610	COG2814	Major facilitator Superfamily
XNRR2_RS12665	COG1196	nuclear chromosome segregation
XNRR2_RS12730	COG3842	ATPase activity
XNRR2_RS12740	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XNRR2_RS12750	COG1253	flavin adenine dinucleotide binding
XNRR2_RS12765	COG0215	cysteine-tRNA ligase activity
XNRR2_RS12780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XNRR2_RS12800	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XNRR2_RS12805	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XNRR2_RS12810	COG1329	Transcriptional regulator
XNRR2_RS12820	COG0745	RESPONSE REGULATOR receiver
XNRR2_RS12825	COG5002	protein histidine kinase activity
XNRR2_RS12840	COG2076	Multidrug Resistance protein
XNRR2_RS12865	COG3311	Transcriptional regulator
XNRR2_RS12920	COG2264	protein methyltransferase activity
XNRR2_RS12925	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
XNRR2_RS12960	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XNRR2_RS12980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XNRR2_RS12985	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XNRR2_RS13015	COG4942	peptidase
XNRR2_RS13020	COG0783	Belongs to the Dps family
XNRR2_RS13025	COG1120	ATPase activity
XNRR2_RS13030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNRR2_RS13050	COG5001	Diguanylate cyclase
XNRR2_RS13065	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XNRR2_RS13070	COG0793	Belongs to the peptidase S41A family
XNRR2_RS13085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XNRR2_RS13090	COG1316	TRANSCRIPTIONal
XNRR2_RS13100	COG0640	Transcriptional regulator
XNRR2_RS13110	COG1252	NADH dehydrogenase
XNRR2_RS13140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XNRR2_RS13150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XNRR2_RS13160	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XNRR2_RS13195	COG2186	Transcriptional regulator
XNRR2_RS13205	COG0318	PFAM AMP-dependent synthetase and ligase
XNRR2_RS13210	COG0825	malonyl-CoA metabolic process
XNRR2_RS13210	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XNRR2_RS13220	COG0789	Transcriptional regulator
XNRR2_RS13235	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XNRR2_RS13240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XNRR2_RS13255	COG0789	Transcriptional regulator
XNRR2_RS13275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XNRR2_RS13290	COG2197	response regulator
XNRR2_RS13320	COG2249	NAD(P)H dehydrogenase (quinone) activity
XNRR2_RS13335	COG0537	adenosine 5'-monophosphoramidase activity
XNRR2_RS13475	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XNRR2_RS13480	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XNRR2_RS13480	COG1754	DNA topoisomerase type I activity
XNRR2_RS13490	COG2890	protein-(glutamine-N5) methyltransferase activity
XNRR2_RS13505	COG1366	Belongs to the anti-sigma-factor antagonist family
XNRR2_RS13510	COG1111	helicase
XNRR2_RS13510	COG1205	dead DEAH box helicase
XNRR2_RS13570	COG0659	secondary active sulfate transmembrane transporter activity
XNRR2_RS13575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XNRR2_RS13580	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XNRR2_RS13590	COG2267	carboxylic ester hydrolase activity
XNRR2_RS13615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XNRR2_RS13625	COG0251	oxidation-reduction process
XNRR2_RS13640	COG0003	Pfam Anion-transporting ATPase
XNRR2_RS13660	COG1408	metallophosphoesterase
XNRR2_RS13675	COG1136	(ABC) transporter
XNRR2_RS13675	COG0577	efflux transmembrane transporter activity
XNRR2_RS13690	COG2318	DinB family
XNRR2_RS13715	COG0596	Alpha beta hydrolase
XNRR2_RS13735	COG2130	NADP-dependent
XNRR2_RS13780	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XNRR2_RS13785	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XNRR2_RS13845	COG1733	regulation of RNA biosynthetic process
XNRR2_RS13855	COG0666	response to abiotic stimulus
XNRR2_RS13870	COG2197	response regulator
XNRR2_RS13950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
XNRR2_RS13980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XNRR2_RS13985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XNRR2_RS14005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XNRR2_RS14020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XNRR2_RS14025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XNRR2_RS14035	COG4221	oxidoreductase activity
XNRR2_RS14050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XNRR2_RS14055	COG2226	methyltransferase
XNRR2_RS14065	COG2197	response regulator
XNRR2_RS14180	COG0596	Alpha beta hydrolase
XNRR2_RS14255	COG1470	cell adhesion involved in biofilm formation
XNRR2_RS14255	COG0366	Alpha amylase catalytic
XNRR2_RS14270	COG0579	oxidoreductase
XNRR2_RS14275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XNRR2_RS14285	COG0667	Aldo Keto reductase
XNRR2_RS14315	COG0542	response to heat
XNRR2_RS14345	COG0513	Belongs to the DEAD box helicase family
XNRR2_RS14380	COG1643	Atp-dependent helicase
XNRR2_RS14415	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XNRR2_RS14430	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XNRR2_RS14435	COG0047	phosphoribosylformylglycinamidine synthase activity
XNRR2_RS14440	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XNRR2_RS14475	COG2197	response regulator
XNRR2_RS14485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XNRR2_RS14500	COG0151	Belongs to the GarS family
XNRR2_RS14525	COG0659	secondary active sulfate transmembrane transporter activity
XNRR2_RS14535	COG2837	iron assimilation
XNRR2_RS14540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XNRR2_RS14610	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XNRR2_RS14645	COG1191	sigma factor activity
XNRR2_RS14650	COG1191	sigma factor activity
XNRR2_RS14665	COG0477	Major facilitator Superfamily
XNRR2_RS14685	COG0477	Major facilitator Superfamily
XNRR2_RS14695	COG0745	RESPONSE REGULATOR receiver
XNRR2_RS14730	COG0318	PFAM AMP-dependent synthetase and ligase
XNRR2_RS14735	COG1595	DNA-templated transcription, initiation
XNRR2_RS14755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XNRR2_RS14770	COG0653	protein targeting
XNRR2_RS14785	COG0006	proline dipeptidase activity
XNRR2_RS14805	COG1999	signal sequence binding
XNRR2_RS14820	COG2837	iron assimilation
XNRR2_RS14825	COG0077	Prephenate dehydratase
XNRR2_RS14830	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XNRR2_RS14835	COG0561	phosphatase activity
XNRR2_RS14855	COG1131	(ABC) transporter
XNRR2_RS14875	COG0561	phosphatase activity
XNRR2_RS14880	COG0739	heme binding
XNRR2_RS14880	COG1196	nuclear chromosome segregation
XNRR2_RS14880	COG0741	lytic transglycosylase activity
XNRR2_RS14890	COG4988	ABC transporter
XNRR2_RS14895	COG1294	oxidase, subunit
XNRR2_RS14900	COG1271	oxidase subunit
XNRR2_RS14905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XNRR2_RS14910	COG1609	Transcriptional regulator
XNRR2_RS14925	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XNRR2_RS14950	COG0662	Cupin 2, conserved barrel domain protein
XNRR2_RS14955	COG1950	PFAM Membrane protein of
XNRR2_RS14960	COG0626	cystathionine gamma-synthase activity
XNRR2_RS15005	COG0110	maltose O-acetyltransferase activity
XNRR2_RS15010	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
XNRR2_RS15090	COG0305	Participates in initiation and elongation during chromosome replication
XNRR2_RS15100	COG0359	binds to the 23S rRNA
XNRR2_RS15105	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XNRR2_RS15110	COG0629	single-stranded DNA binding
XNRR2_RS15115	COG0360	Binds together with S18 to 16S ribosomal RNA
XNRR2_RS15140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XNRR2_RS15165	COG0617	tRNA 3'-terminal CCA addition
XNRR2_RS15180	COG2815	serine threonine protein kinase
XNRR2_RS15180	COG0515	serine threonine protein kinase
XNRR2_RS15185	COG1595	DNA-templated transcription, initiation
XNRR2_RS15195	COG0492	ferredoxin-NADP+ reductase activity
XNRR2_RS15200	COG3118	belongs to the thioredoxin family
XNRR2_RS15215	COG1192	Involved in chromosome partitioning
XNRR2_RS15220	COG0357	Ribosomal RNA small subunit methyltransferase G
XNRR2_RS15230	COG0706	membrane insertase activity
XNRR2_RS15235	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XNRR2_RS15240	COG0594	ribonuclease P activity
XNRR2_RS15245	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XNRR2_RS15250	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XNRR2_RS15255	COG0592	DNA-directed DNA polymerase activity
XNRR2_RS15260	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XNRR2_RS15265	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XNRR2_RS15270	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
XNRR2_RS15275	COG0187	DNA topoisomerase II activity
XNRR2_RS15280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
XNRR2_RS15320	COG0515	serine threonine protein kinase
XNRR2_RS15350	COG1278	Cold shock
XNRR2_RS15355	COG1309	transcriptional regulator
XNRR2_RS15375	COG0705	Rhomboid family
XNRR2_RS15395	COG3764	Sortase (surface protein transpeptidase)
XNRR2_RS15400	COG3764	Sortase (surface protein transpeptidase)
XNRR2_RS15405	COG0515	serine threonine protein kinase
XNRR2_RS15425	COG1716	ATPase activity
XNRR2_RS15430	COG1716	ATPase activity
XNRR2_RS15440	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XNRR2_RS15445	COG1733	regulation of RNA biosynthetic process
XNRR2_RS15485	COG1522	sequence-specific DNA binding
XNRR2_RS15510	COG0303	'Molybdopterin
XNRR2_RS15515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XNRR2_RS15540	COG0515	serine threonine protein kinase
XNRR2_RS15545	COG0515	serine threonine protein kinase
XNRR2_RS15560	COG0022	dehydrogenase e1 component
XNRR2_RS15565	COG0508	dehydrogenase complex catalyzes the overall conversion of
XNRR2_RS15620	COG1362	aminopeptidase activity
XNRR2_RS15640	COG1960	acyl-CoA dehydrogenase activity
XNRR2_RS15755	COG2197	response regulator
XNRR2_RS15765	COG2226	methyltransferase
XNRR2_RS15770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XNRR2_RS15785	COG4221	oxidoreductase activity
XNRR2_RS15795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XNRR2_RS15800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XNRR2_RS15815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XNRR2_RS15835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XNRR2_RS15840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XNRR2_RS15870	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
XNRR2_RS15895	COG0628	permease
XNRR2_RS15905	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XNRR2_RS15915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XNRR2_RS15955	COG1316	TRANSCRIPTIONal
XNRR2_RS15970	COG2268	Band 7 protein
XNRR2_RS15975	COG1937	Protein conserved in bacteria
XNRR2_RS15980	COG1064	alcohol dehydrogenase
XNRR2_RS15985	COG2770	Histidine kinase
XNRR2_RS15985	COG2208	phosphoserine phosphatase activity
XNRR2_RS16015	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XNRR2_RS16035	COG0477	Major facilitator Superfamily
XNRR2_RS16065	COG2181	nitrate reductase activity
XNRR2_RS16065	COG0247	lactate metabolic process
XNRR2_RS16070	COG1434	Gram-negative-bacterium-type cell wall biogenesis
XNRR2_RS16110	COG0717	Belongs to the dCTP deaminase family
XNRR2_RS16120	COG0326	Molecular chaperone. Has ATPase activity
XNRR2_RS16140	COG2814	Major facilitator Superfamily
XNRR2_RS16150	COG1695	Transcriptional regulator
XNRR2_RS16180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XNRR2_RS16180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XNRR2_RS16215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNRR2_RS16220	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNRR2_RS16225	COG1120	ATPase activity
XNRR2_RS16245	COG3547	Transposase (IS116 IS110 IS902 family)
XNRR2_RS16250	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
XNRR2_RS16280	COG1131	(ABC) transporter
XNRR2_RS16285	COG1725	Transcriptional regulator
XNRR2_RS16320	COG0443	Heat shock 70 kDa protein
XNRR2_RS16325	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XNRR2_RS16330	COG0484	heat shock protein binding
XNRR2_RS16335	COG0789	Transcriptional regulator
XNRR2_RS16360	COG0477	Major facilitator Superfamily
XNRR2_RS16375	COG2378	regulation of single-species biofilm formation
XNRR2_RS16425	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XNRR2_RS16440	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XNRR2_RS16445	COG0191	fructose-bisphosphate aldolase activity
XNRR2_RS16450	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
XNRR2_RS16455	COG0477	Major facilitator Superfamily
XNRR2_RS16475	COG3844	kynureninase activity
XNRR2_RS16490	COG4585	Histidine kinase
XNRR2_RS16495	COG2197	response regulator
XNRR2_RS16505	COG1335	isochorismatase
XNRR2_RS16520	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XNRR2_RS16535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XNRR2_RS16540	COG0798	PFAM Bile acid sodium symporter
XNRR2_RS16560	COG2124	cytochrome p450
XNRR2_RS16565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XNRR2_RS16570	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XNRR2_RS16625	COG0509	glycine decarboxylation via glycine cleavage system
XNRR2_RS16635	COG2318	DinB family
XNRR2_RS16655	COG0741	lytic transglycosylase activity
XNRR2_RS16655	COG1196	nuclear chromosome segregation
XNRR2_RS16655	COG0739	heme binding
XNRR2_RS16660	COG0671	phosphoesterase, PA-phosphatase related
XNRR2_RS16670	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS16680	COG1937	Protein conserved in bacteria
XNRR2_RS16690	COG0306	phosphate transporter
XNRR2_RS16695	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XNRR2_RS16750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
XNRR2_RS16755	COG2318	DinB family
XNRR2_RS16795	COG2208	phosphoserine phosphatase activity
XNRR2_RS16795	COG2770	Histidine kinase
XNRR2_RS16805	COG0596	Alpha beta hydrolase
XNRR2_RS16810	COG3629	intracellular signal transduction
XNRR2_RS16810	COG3903	Transcriptional regulator
XNRR2_RS16850	COG1595	DNA-templated transcription, initiation
XNRR2_RS16905	COG2267	carboxylic ester hydrolase activity
XNRR2_RS16940	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XNRR2_RS16950	COG1131	(ABC) transporter
XNRR2_RS16960	COG1725	Transcriptional regulator
XNRR2_RS16965	COG4941	Belongs to the sigma-70 factor family
XNRR2_RS17015	COG0456	acetyltransferase
XNRR2_RS17020	COG0737	Belongs to the 5'-nucleotidase family
XNRR2_RS17025	COG0235	Class ii aldolase
XNRR2_RS17030	COG2160	L-arabinose isomerase activity
XNRR2_RS17040	COG1609	Transcriptional regulator
XNRR2_RS17050	COG1129	ABC transporter
XNRR2_RS17055	COG4214	carbohydrate transport
XNRR2_RS17070	COG0745	RESPONSE REGULATOR receiver
XNRR2_RS17075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XNRR2_RS17080	COG1609	Transcriptional regulator
XNRR2_RS17085	COG0745	RESPONSE REGULATOR receiver
XNRR2_RS17110	COG2897	thiosulfate sulfurtransferase activity
XNRR2_RS17145	COG3485	protocatechuate 3,4-dioxygenase
XNRR2_RS17150	COG0735	belongs to the Fur family
XNRR2_RS17155	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XNRR2_RS17160	COG1490	D-aminoacyl-tRNA deacylase activity
XNRR2_RS17175	COG0789	Transcriptional regulator
XNRR2_RS17180	COG2249	NAD(P)H dehydrogenase (quinone) activity
XNRR2_RS17195	COG1476	TRANSCRIPTIONal
XNRR2_RS17230	COG4106	trans-aconitate 2-methyltransferase activity
XNRR2_RS17250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XNRR2_RS17260	COG2226	methyltransferase
XNRR2_RS17280	COG1309	transcriptional regulator
XNRR2_RS17330	COG0457	Tetratricopeptide repeat
XNRR2_RS17355	COG3103	Sh3 type 3 domain protein
XNRR2_RS17355	COG1388	LysM domain
XNRR2_RS17355	COG0791	NLP P60 protein
XNRR2_RS17365	COG0438	transferase activity, transferring glycosyl groups
XNRR2_RS17390	COG0588	phosphoglycerate mutase activity
XNRR2_RS17410	COG0739	heme binding
XNRR2_RS17425	COG2814	Major facilitator Superfamily
XNRR2_RS17425	COG0477	Major facilitator Superfamily
XNRR2_RS17440	COG2159	amidohydrolase
XNRR2_RS17445	COG2828	Protein conserved in bacteria
XNRR2_RS17450	COG2186	Transcriptional regulator
XNRR2_RS17480	COG0501	Belongs to the peptidase M48B family
XNRR2_RS17485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XNRR2_RS17485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XNRR2_RS17525	COG1289	transmembrane transporter activity
XNRR2_RS17550	COG1012	belongs to the aldehyde dehydrogenase family
XNRR2_RS17555	COG2318	DinB family
XNRR2_RS17565	COG0655	NAD(P)H dehydrogenase (quinone) activity
XNRR2_RS17570	COG0789	Transcriptional regulator
XNRR2_RS17575	COG0586	Pfam SNARE associated Golgi protein
XNRR2_RS17585	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XNRR2_RS17590	COG2027	D-alanyl-D-alanine carboxypeptidase
XNRR2_RS17600	COG0037	tRNA processing
XNRR2_RS17615	COG0302	gtp cyclohydrolase
XNRR2_RS17625	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XNRR2_RS17630	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XNRR2_RS17645	COG0517	IMP dehydrogenase activity
XNRR2_RS17645	COG1125	glycine betaine transport
XNRR2_RS17650	COG1174	glycine betaine transport
XNRR2_RS17655	COG1174	glycine betaine transport
XNRR2_RS17660	COG1732	Glycine betaine
XNRR2_RS17670	COG0477	Major facilitator Superfamily
XNRR2_RS17685	COG0477	Major facilitator Superfamily
XNRR2_RS17750	COG1012	belongs to the aldehyde dehydrogenase family
XNRR2_RS17770	COG4585	Histidine kinase
XNRR2_RS17775	COG2197	response regulator
XNRR2_RS17795	COG0649	NAD binding
XNRR2_RS17810	COG2197	response regulator
XNRR2_RS17825	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XNRR2_RS17830	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
XNRR2_RS17840	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XNRR2_RS17860	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
XNRR2_RS17885	COG0739	heme binding
XNRR2_RS17890	COG2205	protein histidine kinase activity
XNRR2_RS17895	COG0745	RESPONSE REGULATOR receiver
XNRR2_RS17905	COG1595	DNA-templated transcription, initiation
XNRR2_RS17915	COG0671	phosphoesterase, PA-phosphatase related
XNRR2_RS17925	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
XNRR2_RS17960	COG0248	Ppx GppA phosphatase
XNRR2_RS17970	COG1082	Xylose isomerase domain protein TIM barrel
XNRR2_RS17975	COG1309	transcriptional regulator
XNRR2_RS17980	COG0129	dihydroxy-acid dehydratase activity
XNRR2_RS17990	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XNRR2_RS18010	COG1129	ABC transporter
XNRR2_RS18010	COG0842	Transport permease protein
XNRR2_RS18020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
XNRR2_RS18025	COG0180	Tryptophanyl-tRNA synthetase
XNRR2_RS18050	COG2223	nitrite transmembrane transporter activity
XNRR2_RS18055	COG0123	including yeast histone deacetylase and acetoin utilization protein
XNRR2_RS18085	COG4552	Acetyltransferase involved in intracellular survival and related
XNRR2_RS18110	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
XNRR2_RS18115	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XNRR2_RS18120	COG0181	hydroxymethylbilane synthase activity
XNRR2_RS18125	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XNRR2_RS18125	COG1648	precorrin-2 dehydrogenase activity
XNRR2_RS18130	COG0113	porphobilinogen synthase activity
XNRR2_RS18150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XNRR2_RS18155	COG0018	arginyl-trna synthetase
XNRR2_RS18160	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
XNRR2_RS18185	COG1690	Belongs to the RtcB family
XNRR2_RS18190	COG0659	secondary active sulfate transmembrane transporter activity
XNRR2_RS18235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XNRR2_RS18240	COG0406	alpha-ribazole phosphatase activity
XNRR2_RS18250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XNRR2_RS18255	COG0785	Cytochrome C biogenesis protein
XNRR2_RS18265	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XNRR2_RS18280	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
XNRR2_RS18285	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XNRR2_RS18290	COG0163	prenyltransferase activity
XNRR2_RS18305	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
XNRR2_RS18320	COG1301	dicarboxylic acid transport
XNRR2_RS18335	COG1131	(ABC) transporter
XNRR2_RS18340	COG3559	Exporter of polyketide antibiotics
XNRR2_RS18370	COG0183	Belongs to the thiolase family
XNRR2_RS18385	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
XNRR2_RS18505	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
XNRR2_RS18565	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
XNRR2_RS18575	COG2226	methyltransferase
XNRR2_RS18600	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XNRR2_RS18605	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XNRR2_RS18610	COG0649	NAD binding
XNRR2_RS18620	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XNRR2_RS18625	COG1034	ATP synthesis coupled electron transport
XNRR2_RS18630	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XNRR2_RS18635	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XNRR2_RS18640	COG0839	Belongs to the complex I subunit 6 family
XNRR2_RS18645	COG0713	ATP synthesis coupled electron transport
XNRR2_RS18650	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XNRR2_RS18660	COG1007	ATP synthesis coupled electron transport
XNRR2_RS18665	COG0514	ATP-dependent DNA helicase (RecQ)
XNRR2_RS18685	COG0561	phosphatase activity
XNRR2_RS18695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XNRR2_RS18710	COG3104	oligopeptide transport
XNRR2_RS18775	COG0488	(ABC) transporter
XNRR2_RS18785	COG0702	epimerase
XNRR2_RS18790	COG1733	regulation of RNA biosynthetic process
XNRR2_RS18795	COG1013	pyruvate-flavodoxin oxidoreductase activity
XNRR2_RS18800	COG0674	pyruvate-flavodoxin oxidoreductase activity
XNRR2_RS18800	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
XNRR2_RS18805	COG2197	response regulator
XNRR2_RS18810	COG4585	Histidine kinase
XNRR2_RS18820	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XNRR2_RS18825	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XNRR2_RS18830	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XNRR2_RS18835	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XNRR2_RS18840	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XNRR2_RS18845	COG0839	Belongs to the complex I subunit 6 family
XNRR2_RS18850	COG0713	ATP synthesis coupled electron transport
XNRR2_RS18855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XNRR2_RS18865	COG1007	ATP synthesis coupled electron transport
XNRR2_RS18870	COG0501	Belongs to the peptidase M48B family
XNRR2_RS18875	COG3304	Inner membrane component domain
XNRR2_RS18880	COG2261	transglycosylase associated protein
XNRR2_RS18885	COG1666	GTP binding
XNRR2_RS18900	COG0702	epimerase
XNRR2_RS18905	COG0402	S-adenosylhomocysteine deaminase activity
XNRR2_RS18920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XNRR2_RS18925	COG2030	dehydratase
XNRR2_RS18935	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XNRR2_RS18945	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
XNRR2_RS18950	COG0436	Aminotransferase
XNRR2_RS18975	COG0081	regulation of translation
XNRR2_RS18985	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XNRR2_RS18990	COG0222	ribosome binding
XNRR2_RS18995	COG0085	RNA polymerase activity
XNRR2_RS19000	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XNRR2_RS19035	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XNRR2_RS19040	COG0049	tRNA binding
XNRR2_RS19045	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XNRR2_RS19065	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XNRR2_RS19075	COG0051	transcription antitermination factor activity, RNA binding
XNRR2_RS19080	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XNRR2_RS19085	COG0088	Forms part of the polypeptide exit tunnel
XNRR2_RS19090	COG0089	rRNA binding
XNRR2_RS19095	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XNRR2_RS19100	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XNRR2_RS19105	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XNRR2_RS19110	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XNRR2_RS19115	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XNRR2_RS19120	COG0255	Belongs to the universal ribosomal protein uL29 family
XNRR2_RS19125	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XNRR2_RS19130	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XNRR2_RS19135	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XNRR2_RS19140	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XNRR2_RS19145	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XNRR2_RS19150	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XNRR2_RS19155	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XNRR2_RS19160	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XNRR2_RS19165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XNRR2_RS19170	COG1841	ribosomal large subunit assembly
XNRR2_RS19175	COG0200	Binds to the 23S rRNA
XNRR2_RS19180	COG0201	protein transport
XNRR2_RS19185	COG0563	adenylate kinase activity
XNRR2_RS19195	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XNRR2_RS19200	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XNRR2_RS19205	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XNRR2_RS19210	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XNRR2_RS19220	COG0203	ribosomal protein L17
XNRR2_RS19225	COG0101	tRNA pseudouridine synthase activity
XNRR2_RS19235	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XNRR2_RS19240	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XNRR2_RS19245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XNRR2_RS19250	COG1072	(Pantothenic acid kinase))
XNRR2_RS19265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XNRR2_RS19280	COG4977	sequence-specific DNA binding
XNRR2_RS19295	COG0736	holo-[acyl-carrier-protein] synthase activity
XNRR2_RS19360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XNRR2_RS19365	COG2267	carboxylic ester hydrolase activity
XNRR2_RS19370	COG0802	atpase or kinase
XNRR2_RS19395	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XNRR2_RS19430	COG0726	polysaccharide deacetylase
XNRR2_RS19445	COG4221	oxidoreductase activity
XNRR2_RS19450	COG0583	DNA-binding transcription factor activity
XNRR2_RS19460	COG2197	response regulator
XNRR2_RS19465	COG1595	DNA-templated transcription, initiation
XNRR2_RS19475	COG0516	GMP reductase activity
XNRR2_RS19485	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
XNRR2_RS19530	COG1012	belongs to the aldehyde dehydrogenase family
XNRR2_RS19550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XNRR2_RS19550	COG0519	Catalyzes the synthesis of GMP from XMP
XNRR2_RS19560	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS19600	COG2197	response regulator
XNRR2_RS19605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XNRR2_RS19650	COG1846	Transcriptional regulator
XNRR2_RS19650	COG0456	acetyltransferase
XNRR2_RS19660	COG1228	amidohydrolase
XNRR2_RS19680	COG0791	NLP P60 protein
XNRR2_RS19720	COG2066	Belongs to the glutaminase family
XNRR2_RS19725	COG0739	heme binding
XNRR2_RS19725	COG1196	nuclear chromosome segregation
XNRR2_RS19725	COG0741	lytic transglycosylase activity
XNRR2_RS19730	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
XNRR2_RS19735	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XNRR2_RS19735	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XNRR2_RS19750	COG0714	Associated with various cellular activities
XNRR2_RS19755	COG2425	protein containing a von Willebrand factor type A (vWA) domain
XNRR2_RS19760	COG3552	Protein containing von Willebrand factor type A (VWA) domain
XNRR2_RS19765	COG0045	succinate-CoA ligase (ADP-forming) activity
XNRR2_RS19795	COG0138	bifunctional purine biosynthesis protein purh
XNRR2_RS19805	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XNRR2_RS19830	COG0039	L-malate dehydrogenase activity
XNRR2_RS19850	COG1012	belongs to the aldehyde dehydrogenase family
XNRR2_RS19860	COG4175	Glycine betaine
XNRR2_RS19860	COG0517	IMP dehydrogenase activity
XNRR2_RS19890	COG0395	ABC-type sugar transport system, permease component
XNRR2_RS19895	COG1175	transmembrane transport
XNRR2_RS19915	COG2362	D-Aminopeptidase
XNRR2_RS19920	COG1609	Transcriptional regulator
XNRR2_RS19930	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XNRR2_RS19935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XNRR2_RS19945	COG0754	glutathionylspermidine amidase activity
XNRR2_RS19955	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XNRR2_RS19990	COG0180	Tryptophanyl-tRNA synthetase
XNRR2_RS20030	COG1295	ribonuclease BN
XNRR2_RS20045	COG1408	metallophosphoesterase
XNRR2_RS20080	COG1309	transcriptional regulator
XNRR2_RS20095	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XNRR2_RS20100	COG1053	succinate dehydrogenase
XNRR2_RS20110	COG2009	succinate dehydrogenase
XNRR2_RS20150	COG1215	transferase activity, transferring glycosyl groups
XNRR2_RS20155	COG1595	DNA-templated transcription, initiation
XNRR2_RS20225	COG1216	Glycosyl transferase, family 2
XNRR2_RS20235	COG1083	cytidylyl-transferase
XNRR2_RS20240	COG2089	acid synthase
XNRR2_RS20250	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
XNRR2_RS20250	COG1473	amidohydrolase
XNRR2_RS20345	COG2814	Major facilitator Superfamily
XNRR2_RS20350	COG0583	DNA-binding transcription factor activity
XNRR2_RS20375	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
XNRR2_RS20400	COG2205	protein histidine kinase activity
XNRR2_RS20405	COG0745	RESPONSE REGULATOR receiver
XNRR2_RS20410	COG1595	DNA-templated transcription, initiation
XNRR2_RS20455	COG1012	belongs to the aldehyde dehydrogenase family
XNRR2_RS20475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XNRR2_RS20515	COG4770	biotin carboxylase activity
XNRR2_RS20525	COG0424	maF-like protein
XNRR2_RS20540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XNRR2_RS20550	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XNRR2_RS20555	COG1024	Enoyl-CoA hydratase
XNRR2_RS20565	COG2986	histidine ammonia-lyase
XNRR2_RS20585	COG1136	(ABC) transporter
XNRR2_RS20590	COG1064	alcohol dehydrogenase
XNRR2_RS20595	COG2318	DinB family
XNRR2_RS20620	COG2255	four-way junction helicase activity
XNRR2_RS20625	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XNRR2_RS20640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XNRR2_RS20650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
XNRR2_RS20685	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XNRR2_RS20710	COG1331	Highly conserved protein containing a thioredoxin domain
XNRR2_RS20730	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
XNRR2_RS20760	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
XNRR2_RS20775	COG1414	Transcriptional regulator
XNRR2_RS20780	COG0251	oxidation-reduction process
XNRR2_RS20860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XNRR2_RS20895	COG2894	cell division
XNRR2_RS20960	COG2814	Major facilitator Superfamily
XNRR2_RS20965	COG0656	L-ascorbic acid biosynthetic process
XNRR2_RS20970	COG2304	oxidoreductase activity
XNRR2_RS20980	COG3548	integral membrane protein
XNRR2_RS20990	COG0667	Aldo Keto reductase
XNRR2_RS20995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XNRR2_RS21000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XNRR2_RS21020	COG0450	alkyl hydroperoxide reductase
XNRR2_RS21025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XNRR2_RS21035	COG1136	(ABC) transporter
XNRR2_RS21055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XNRR2_RS21070	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XNRR2_RS21080	COG0114	fumarate hydratase activity
XNRR2_RS21090	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
XNRR2_RS21090	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
XNRR2_RS21100	COG0515	serine threonine protein kinase
XNRR2_RS21125	COG0778	Nitroreductase
XNRR2_RS21130	COG1722	exodeoxyribonuclease VII activity
XNRR2_RS21135	COG1570	exodeoxyribonuclease VII activity
XNRR2_RS21140	COG0531	amino acid
XNRR2_RS21145	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XNRR2_RS21160	COG0012	GTP binding
XNRR2_RS21190	COG0709	Synthesizes selenophosphate from selenide and ATP
XNRR2_RS21225	COG0406	alpha-ribazole phosphatase activity
XNRR2_RS21250	COG0745	RESPONSE REGULATOR receiver
XNRR2_RS21320	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XNRR2_RS21325	COG4977	sequence-specific DNA binding
XNRR2_RS21340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XNRR2_RS21365	COG3486	L-lysine 6-monooxygenase (NADPH) activity
XNRR2_RS21395	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS21405	COG3655	Transcriptional regulator
XNRR2_RS21465	COG1960	acyl-CoA dehydrogenase activity
XNRR2_RS21480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XNRR2_RS21485	COG1309	transcriptional regulator
XNRR2_RS21495	COG1946	Acyl-CoA thioesterase
XNRR2_RS21535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XNRR2_RS21545	COG3960	tartronate-semialdehyde synthase activity
XNRR2_RS21565	COG1472	Belongs to the glycosyl hydrolase 3 family
XNRR2_RS21570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XNRR2_RS21615	COG3718	enzyme involved in inositol metabolism
XNRR2_RS21620	COG3962	Belongs to the TPP enzyme family
XNRR2_RS21635	COG1131	(ABC) transporter
XNRR2_RS21665	COG3629	intracellular signal transduction
XNRR2_RS21665	COG3903	Transcriptional regulator
XNRR2_RS21740	COG0629	single-stranded DNA binding
XNRR2_RS21775	COG1136	(ABC) transporter
XNRR2_RS21795	COG0667	Aldo Keto reductase
XNRR2_RS21800	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XNRR2_RS21830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XNRR2_RS21855	COG1486	melibiose metabolic process
XNRR2_RS21865	COG0668	transmembrane transport
XNRR2_RS21880	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XNRR2_RS21900	COG0583	DNA-binding transcription factor activity
XNRR2_RS21930	COG4266	Belongs to the allantoicase family
XNRR2_RS21965	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XNRR2_RS21970	COG0076	glutamate decarboxylase activity
XNRR2_RS21975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XNRR2_RS21980	COG1113	amino acid transport
XNRR2_RS21985	COG1113	amino acid transport
XNRR2_RS21990	COG1268	BioY protein
XNRR2_RS21995	COG1113	amino acid transport
XNRR2_RS22010	COG4552	Acetyltransferase involved in intracellular survival and related
XNRR2_RS22020	COG0475	glutathione-regulated potassium exporter activity
XNRR2_RS22025	COG3594	Acyltransferase
XNRR2_RS22045	COG0544	peptidyl-prolyl cis-trans isomerase activity
XNRR2_RS22050	COG0740	serine-type endopeptidase activity
XNRR2_RS22055	COG0740	serine-type endopeptidase activity
XNRR2_RS22060	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XNRR2_RS22070	COG0525	valine-tRNA ligase activity
XNRR2_RS22075	COG0285	dihydrofolate synthase activity
XNRR2_RS22085	COG0105	UTP biosynthetic process
XNRR2_RS22090	COG1077	Cell shape determining protein MreB Mrl
XNRR2_RS22110	COG0772	Belongs to the SEDS family
XNRR2_RS22135	COG1530	ribonuclease E activity
XNRR2_RS22140	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XNRR2_RS22145	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XNRR2_RS22150	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XNRR2_RS22170	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XNRR2_RS22180	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XNRR2_RS22195	COG0501	Belongs to the peptidase M48B family
XNRR2_RS22210	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XNRR2_RS22220	COG0799	negative regulation of ribosome biogenesis
XNRR2_RS22225	COG0588	phosphoglycerate mutase activity
XNRR2_RS22250	COG0495	leucyl-tRNA aminoacylation
XNRR2_RS22260	COG1307	EDD domain protein, DegV family
XNRR2_RS22265	COG1555	photosystem II stabilization
XNRR2_RS22275	COG2353	YceI-like domain
XNRR2_RS22290	COG0268	Binds directly to 16S ribosomal RNA
XNRR2_RS22295	COG0481	GTPase activity
XNRR2_RS22330	COG0484	heat shock protein binding
XNRR2_RS22345	COG4946	Tricorn protease homolog
XNRR2_RS22345	COG0793	Belongs to the peptidase S41A family
XNRR2_RS22350	COG0537	adenosine 5'-monophosphoramidase activity
XNRR2_RS22355	COG1234	tRNA 3'-trailer cleavage
XNRR2_RS22375	COG2515	1-aminocyclopropane-1-carboxylate deaminase
XNRR2_RS22380	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
XNRR2_RS22405	COG1486	melibiose metabolic process
XNRR2_RS22410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XNRR2_RS22430	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XNRR2_RS22440	COG2315	Protein conserved in bacteria
XNRR2_RS22450	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XNRR2_RS22465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XNRR2_RS22480	COG1381	Involved in DNA repair and RecF pathway recombination
XNRR2_RS22485	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XNRR2_RS22495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XNRR2_RS22500	COG1121	(ABC) transporter
XNRR2_RS22510	COG0423	glycine-tRNA ligase activity
XNRR2_RS22580	COG0189	ligase activity
XNRR2_RS22590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XNRR2_RS22605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XNRR2_RS22610	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
XNRR2_RS22620	COG3467	pyridoxamine 5'-phosphate
XNRR2_RS22650	COG1846	Transcriptional regulator
XNRR2_RS22650	COG1940	carbohydrate kinase activity
XNRR2_RS22660	COG0574	Belongs to the PEP-utilizing enzyme family
XNRR2_RS22660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XNRR2_RS22675	COG1324	tolerance protein
XNRR2_RS22685	COG0829	nickel cation binding
XNRR2_RS22690	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XNRR2_RS22695	COG0830	nickel cation binding
XNRR2_RS22700	COG0804	urea catabolic process
XNRR2_RS22705	COG0832	Belongs to the urease beta subunit family
XNRR2_RS22715	COG0738	Major facilitator superfamily
XNRR2_RS22720	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS22735	COG2226	methyltransferase
XNRR2_RS22775	COG1070	Carbohydrate kinase
XNRR2_RS22795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XNRR2_RS22800	COG0358	DNA primase activity
XNRR2_RS22810	COG3290	protein histidine kinase activity
XNRR2_RS22815	COG4565	transcriptional regulatory protein
XNRR2_RS22820	COG2851	Citrate transporter
XNRR2_RS22830	COG0232	Belongs to the dGTPase family. Type 2 subfamily
XNRR2_RS22850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XNRR2_RS22875	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS22890	COG2890	protein-(glutamine-N5) methyltransferase activity
XNRR2_RS22905	COG1077	Cell shape determining protein MreB Mrl
XNRR2_RS22930	COG2130	NADP-dependent
XNRR2_RS22935	COG1764	response to oxidative stress
XNRR2_RS22965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XNRR2_RS22970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XNRR2_RS22975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XNRR2_RS22990	COG1741	Belongs to the pirin family
XNRR2_RS23005	COG0789	Transcriptional regulator
XNRR2_RS23010	COG0667	Aldo Keto reductase
XNRR2_RS23025	COG2197	response regulator
XNRR2_RS23030	COG4585	Histidine kinase
XNRR2_RS23050	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
XNRR2_RS23095	COG1358	cellular component organization or biogenesis
XNRR2_RS23110	COG0586	Pfam SNARE associated Golgi protein
XNRR2_RS23215	COG3845	ABC transporter
XNRR2_RS23230	COG1657	PFAM Prenyltransferase squalene oxidase
XNRR2_RS23235	COG0438	transferase activity, transferring glycosyl groups
XNRR2_RS23265	COG0477	Major facilitator Superfamily
XNRR2_RS23270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XNRR2_RS23275	COG1960	acyl-CoA dehydrogenase activity
XNRR2_RS23290	COG2197	response regulator
XNRR2_RS23295	COG0346	lactoylglutathione lyase activity
XNRR2_RS23300	COG4585	Histidine kinase
XNRR2_RS23310	COG1131	(ABC) transporter
XNRR2_RS23325	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
XNRR2_RS23340	COG0800	Aldolase
XNRR2_RS23345	COG3022	response to hydroperoxide
XNRR2_RS23385	COG1733	regulation of RNA biosynthetic process
XNRR2_RS23405	COG2226	methyltransferase
XNRR2_RS23410	COG0384	phenazine biosynthesis protein PhzF
XNRR2_RS23430	COG0076	glutamate decarboxylase activity
XNRR2_RS23440	COG2814	Major facilitator Superfamily
XNRR2_RS23445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XNRR2_RS23455	COG1834	amidinotransferase
XNRR2_RS23475	COG1120	ATPase activity
XNRR2_RS23480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNRR2_RS23485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XNRR2_RS23530	COG1994	Peptidase M50
XNRR2_RS23535	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XNRR2_RS23550	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XNRR2_RS23550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XNRR2_RS23555	COG2132	Multicopper oxidase
XNRR2_RS23575	COG0174	glutamine synthetase
XNRR2_RS23600	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XNRR2_RS23615	COG0531	amino acid
XNRR2_RS23620	COG1228	amidohydrolase
XNRR2_RS23635	COG1609	Transcriptional regulator
XNRR2_RS23640	COG2182	Extracellular solute-binding protein
XNRR2_RS23645	COG1175	transmembrane transport
XNRR2_RS23650	COG0395	ABC-type sugar transport system, permease component
XNRR2_RS23655	COG0366	Alpha amylase catalytic
XNRR2_RS23680	COG1309	transcriptional regulator
XNRR2_RS23705	COG0745	RESPONSE REGULATOR receiver
XNRR2_RS23735	COG1012	belongs to the aldehyde dehydrogenase family
XNRR2_RS23800	COG2326	polyphosphate kinase activity
XNRR2_RS23810	COG2376	Dihydroxyacetone kinase
XNRR2_RS23820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XNRR2_RS23860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XNRR2_RS23865	COG0321	lipoyl(octanoyl) transferase activity
XNRR2_RS23875	COG0456	acetyltransferase
XNRR2_RS23900	COG4221	oxidoreductase activity
XNRR2_RS23915	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
XNRR2_RS23925	COG0508	dehydrogenase complex catalyzes the overall conversion of
XNRR2_RS23930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XNRR2_RS23935	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XNRR2_RS23940	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
XNRR2_RS23950	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XNRR2_RS23995	COG2197	response regulator
XNRR2_RS24000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XNRR2_RS24005	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
XNRR2_RS24030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XNRR2_RS24035	COG1104	cysteine desulfurase activity
XNRR2_RS24040	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XNRR2_RS24045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XNRR2_RS24055	COG1376	ErfK ybiS ycfS ynhG family protein
XNRR2_RS24065	COG1845	cytochrome c oxidase, subunit III
XNRR2_RS24070	COG2010	Cytochrome c
XNRR2_RS24075	COG0723	plastoquinol--plastocyanin reductase activity
XNRR2_RS24080	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XNRR2_RS24085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XNRR2_RS24090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XNRR2_RS24095	COG1929	Belongs to the glycerate kinase type-1 family
XNRR2_RS24105	COG0745	RESPONSE REGULATOR receiver
XNRR2_RS24110	COG5002	protein histidine kinase activity
XNRR2_RS24125	COG0705	Rhomboid family
XNRR2_RS24160	COG0438	transferase activity, transferring glycosyl groups
XNRR2_RS24180	COG0003	Pfam Anion-transporting ATPase
XNRR2_RS24190	COG1940	carbohydrate kinase activity
XNRR2_RS24215	COG4585	Histidine kinase
XNRR2_RS24220	COG2197	response regulator
XNRR2_RS24225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XNRR2_RS24240	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XNRR2_RS24245	COG0243	molybdopterin cofactor binding
XNRR2_RS24250	COG2193	ferroxidase activity
XNRR2_RS24255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XNRR2_RS24260	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
XNRR2_RS24265	COG2815	serine threonine protein kinase
XNRR2_RS24265	COG0515	serine threonine protein kinase
XNRR2_RS24270	COG2022	thiamine diphosphate biosynthetic process
XNRR2_RS24280	COG2022	thiamine diphosphate biosynthetic process
XNRR2_RS24280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XNRR2_RS24285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XNRR2_RS24295	COG0352	thiamine-phosphate diphosphorylase activity
XNRR2_RS24315	COG1309	transcriptional regulator
XNRR2_RS24325	COG1121	(ABC) transporter
XNRR2_RS24330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XNRR2_RS24350	COG0714	Associated with various cellular activities
XNRR2_RS24360	COG0275	rRNA processing
XNRR2_RS24375	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XNRR2_RS24385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XNRR2_RS24390	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XNRR2_RS24400	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XNRR2_RS24405	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XNRR2_RS24410	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
XNRR2_RS24425	COG1799	cell septum assembly
XNRR2_RS24435	COG3599	regulation of cell shape
XNRR2_RS24440	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XNRR2_RS24450	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XNRR2_RS24460	COG2153	protein acetylation
XNRR2_RS24475	COG0515	serine threonine protein kinase
XNRR2_RS24495	COG0587	DNA-directed DNA polymerase activity
XNRR2_RS24505	COG1432	Conserved Protein
XNRR2_RS24525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XNRR2_RS24545	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XNRR2_RS24550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XNRR2_RS24555	COG0131	Imidazoleglycerol-phosphate dehydratase
XNRR2_RS24565	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XNRR2_RS24570	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XNRR2_RS24575	COG0251	oxidation-reduction process
XNRR2_RS24580	COG0107	imidazoleglycerol-phosphate synthase activity
XNRR2_RS24595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XNRR2_RS24625	COG0134	indole-3-glycerol-phosphate synthase activity
XNRR2_RS24630	COG0133	tryptophan synthase activity
XNRR2_RS24635	COG0159	tryptophan synthase activity
XNRR2_RS24645	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XNRR2_RS24655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XNRR2_RS24660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XNRR2_RS24690	COG0070	glutamate synthase
XNRR2_RS24690	COG0067	glutamate synthase
XNRR2_RS24690	COG0069	glutamate synthase activity
XNRR2_RS24705	COG1278	Cold shock
XNRR2_RS24710	COG0513	Belongs to the DEAD box helicase family
XNRR2_RS24720	COG0287	Prephenate dehydrogenase
XNRR2_RS24720	COG1605	Chorismate mutase
XNRR2_RS24750	COG3486	L-lysine 6-monooxygenase (NADPH) activity
XNRR2_RS24755	COG0737	Belongs to the 5'-nucleotidase family
XNRR2_RS24795	COG0559	Belongs to the binding-protein-dependent transport system permease family
XNRR2_RS24805	COG2746	aminoglycoside 3-N-acetyltransferase activity
XNRR2_RS24810	COG2050	protein possibly involved in aromatic compounds catabolism
XNRR2_RS24830	COG1643	Atp-dependent helicase
XNRR2_RS24835	COG2226	methyltransferase
XNRR2_RS24855	COG0237	dephospho-CoA kinase activity
XNRR2_RS24880	COG1288	antiporter activity
XNRR2_RS24930	COG0477	Major facilitator Superfamily
XNRR2_RS24940	COG0584	glycerophosphoryl diester phosphodiesterase
XNRR2_RS24950	COG0556	nucleotide-excision repair
XNRR2_RS24970	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XNRR2_RS24975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XNRR2_RS24985	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XNRR2_RS25000	COG0322	excinuclease ABC activity
XNRR2_RS25005	COG1660	Displays ATPase and GTPase activities
XNRR2_RS25015	COG1481	regulation of sporulation
XNRR2_RS25020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XNRR2_RS25025	COG0126	phosphoglycerate kinase activity
XNRR2_RS25030	COG0149	triose-phosphate isomerase activity
XNRR2_RS25035	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XNRR2_RS25045	COG0166	Belongs to the GPI family
XNRR2_RS25050	COG0363	glucosamine-6-phosphate deaminase activity
XNRR2_RS25065	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XNRR2_RS25070	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XNRR2_RS25075	COG0109	protoheme IX farnesyltransferase activity
XNRR2_RS25100	COG1131	(ABC) transporter
XNRR2_RS25115	COG0719	Fe-S assembly protein
XNRR2_RS25125	COG0396	ATPase activity
XNRR2_RS25130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XNRR2_RS25135	COG0822	iron-sulfur transferase activity
XNRR2_RS25145	COG2171	N-acyltransferase activity
XNRR2_RS25180	COG2197	response regulator
XNRR2_RS25185	COG4585	Histidine kinase
XNRR2_RS25215	COG1902	pentaerythritol trinitrate reductase activity
XNRR2_RS25220	COG5285	phytanoyl-CoA dioxygenase
XNRR2_RS25225	COG1917	Cupin 2, conserved barrel domain protein
XNRR2_RS25235	COG0456	acetyltransferase
XNRR2_RS25240	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XNRR2_RS25270	COG1797	cobyrinic acid a,c-diamide synthase activity
XNRR2_RS25285	COG1492	cobalamin metabolic process
XNRR2_RS25305	COG0235	Class ii aldolase
XNRR2_RS25325	COG0488	(ABC) transporter
XNRR2_RS25380	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XNRR2_RS25400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XNRR2_RS25415	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XNRR2_RS25420	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XNRR2_RS25430	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
XNRR2_RS25450	COG2261	transglycosylase associated protein
XNRR2_RS25455	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XNRR2_RS25465	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XNRR2_RS25475	COG2186	Transcriptional regulator
XNRR2_RS25480	COG2807	transmembrane transport
XNRR2_RS25495	COG3830	Belongs to the UPF0237 family
XNRR2_RS25495	COG0560	Phosphoserine phosphatase
XNRR2_RS25500	COG1131	(ABC) transporter
XNRR2_RS25500	COG0842	Transport permease protein
XNRR2_RS25500	COG1716	ATPase activity
XNRR2_RS25510	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XNRR2_RS25525	COG2197	response regulator
XNRR2_RS25540	COG1119	ATPase activity
XNRR2_RS25560	COG1881	PFAM PEBP family protein
XNRR2_RS25570	COG2094	Belongs to the DNA glycosylase MPG family
XNRR2_RS25605	COG0647	UMP catabolic process
XNRR2_RS25625	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XNRR2_RS25630	COG0497	DNA recombination
XNRR2_RS25645	COG0297	glycogen (starch) synthase activity
XNRR2_RS25650	COG3896	Chloramphenicol phosphotransferase-like protein
XNRR2_RS25660	COG3387	PFAM Glycoside hydrolase 15-related
XNRR2_RS25665	COG0504	CTP synthase activity
XNRR2_RS25670	COG0494	nUDIX hydrolase
XNRR2_RS25680	COG0686	Belongs to the AlaDH PNT family
XNRR2_RS25695	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XNRR2_RS25700	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XNRR2_RS25705	COG1187	pseudouridine synthase activity
XNRR2_RS25715	COG1397	ADP-ribosylglycohydrolase
XNRR2_RS25720	COG3541	Predicted nucleotidyltransferase
XNRR2_RS25735	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XNRR2_RS25745	COG1160	GTP binding
XNRR2_RS25765	COG0438	transferase activity, transferring glycosyl groups
XNRR2_RS25785	COG0671	phosphoesterase, PA-phosphatase related
XNRR2_RS25795	COG0477	Major facilitator Superfamily
XNRR2_RS25800	COG1799	cell septum assembly
XNRR2_RS25840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XNRR2_RS25860	COG0330	HflC and HflK could
XNRR2_RS25875	COG0587	DNA-directed DNA polymerase activity
XNRR2_RS25880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XNRR2_RS25945	COG1216	Glycosyl transferase, family 2
XNRR2_RS25970	COG2755	lipolytic protein G-D-S-L family
XNRR2_RS25990	COG3973	AAA domain
XNRR2_RS25995	COG2188	Transcriptional regulator
XNRR2_RS26000	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XNRR2_RS26025	COG1309	transcriptional regulator
XNRR2_RS26065	COG3876	Protein conserved in bacteria
XNRR2_RS26075	COG0488	(ABC) transporter
XNRR2_RS26090	COG0318	PFAM AMP-dependent synthetase and ligase
XNRR2_RS26100	COG1960	acyl-CoA dehydrogenase activity
XNRR2_RS26120	COG2149	membrane
XNRR2_RS26125	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
XNRR2_RS26165	COG3265	gluconokinase activity
XNRR2_RS26175	COG3012	SEC-C Motif Domain Protein
XNRR2_RS26180	COG3189	MarR family transcriptional regulator
XNRR2_RS26190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XNRR2_RS26220	COG0667	Aldo Keto reductase
XNRR2_RS26225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XNRR2_RS26235	COG0598	Magnesium transport protein CorA
XNRR2_RS26255	COG0215	cysteine-tRNA ligase activity
XNRR2_RS26270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
XNRR2_RS26275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XNRR2_RS26290	COG0646	methionine synthase
XNRR2_RS26290	COG1410	methionine synthase
XNRR2_RS26300	COG0747	negative chemotaxis
XNRR2_RS26305	COG2197	response regulator
XNRR2_RS26315	COG0517	IMP dehydrogenase activity
XNRR2_RS26315	COG1994	Peptidase M50
XNRR2_RS26335	COG1222	aaa ATPase
XNRR2_RS26340	COG4122	O-methyltransferase activity
XNRR2_RS26350	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
XNRR2_RS26355	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
XNRR2_RS26370	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
XNRR2_RS26405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XNRR2_RS26410	COG0805	protein transport
XNRR2_RS26425	COG2124	cytochrome p450
XNRR2_RS26455	COG0564	pseudouridine synthase activity
XNRR2_RS26465	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XNRR2_RS26475	COG1595	DNA-templated transcription, initiation
XNRR2_RS26485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XNRR2_RS26490	COG4175	Glycine betaine
XNRR2_RS26490	COG0517	IMP dehydrogenase activity
XNRR2_RS26515	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XNRR2_RS26520	COG0531	amino acid
XNRR2_RS26525	COG2186	Transcriptional regulator
XNRR2_RS26530	COG0174	glutamine synthetase
XNRR2_RS26535	COG1012	belongs to the aldehyde dehydrogenase family
XNRR2_RS26570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XNRR2_RS26580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XNRR2_RS26585	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XNRR2_RS26590	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
XNRR2_RS26595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XNRR2_RS26605	COG5002	protein histidine kinase activity
XNRR2_RS26610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XNRR2_RS26615	COG0072	phenylalanine-tRNA ligase activity
XNRR2_RS26615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XNRR2_RS26645	COG0697	spore germination
XNRR2_RS26650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XNRR2_RS26670	COG0477	Major facilitator Superfamily
XNRR2_RS26690	COG2838	Isocitrate dehydrogenase
XNRR2_RS26705	COG1309	transcriptional regulator
XNRR2_RS26720	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XNRR2_RS26760	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XNRR2_RS26765	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
XNRR2_RS26770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XNRR2_RS26775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XNRR2_RS26780	COG1438	arginine binding
XNRR2_RS26785	COG4585	Histidine kinase
XNRR2_RS26790	COG2197	response regulator
XNRR2_RS26800	COG2409	Drug exporters of the RND superfamily
XNRR2_RS26805	COG0385	Bile acid
XNRR2_RS26815	COG0165	Argininosuccinate lyase
XNRR2_RS26835	COG0477	Major facilitator Superfamily
XNRR2_RS26840	COG0204	Acyl-transferase
XNRR2_RS26840	COG0318	PFAM AMP-dependent synthetase and ligase
XNRR2_RS26845	COG0584	glycerophosphoryl diester phosphodiesterase
XNRR2_RS26870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XNRR2_RS26875	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XNRR2_RS26880	COG2011	ABC-type metal ion transport system permease component
XNRR2_RS26885	COG1464	Belongs to the NlpA lipoprotein family
XNRR2_RS26890	COG1464	Belongs to the NlpA lipoprotein family
XNRR2_RS26905	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XNRR2_RS26910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XNRR2_RS26910	COG1648	precorrin-2 dehydrogenase activity
XNRR2_RS26975	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XNRR2_RS26985	COG0456	acetyltransferase
XNRR2_RS27045	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XNRR2_RS27050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XNRR2_RS27065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XNRR2_RS27070	COG1560	Kdo2-lipid A biosynthetic process
XNRR2_RS27075	COG0438	transferase activity, transferring glycosyl groups
XNRR2_RS27085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
XNRR2_RS27090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
XNRR2_RS27095	COG0217	transcriptional regulatory protein
XNRR2_RS27100	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XNRR2_RS27105	COG0632	four-way junction helicase activity
XNRR2_RS27110	COG2255	four-way junction helicase activity
XNRR2_RS27120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XNRR2_RS27125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XNRR2_RS27130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XNRR2_RS27135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XNRR2_RS27145	COG1196	nuclear chromosome segregation
XNRR2_RS27150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XNRR2_RS27160	COG0124	histidyl-tRNA synthetase
XNRR2_RS27175	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XNRR2_RS27190	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XNRR2_RS27195	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XNRR2_RS27200	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XNRR2_RS27205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XNRR2_RS27210	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XNRR2_RS27215	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XNRR2_RS27220	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XNRR2_RS27230	COG0006	proline dipeptidase activity
XNRR2_RS27235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XNRR2_RS27240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XNRR2_RS27250	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
XNRR2_RS27255	COG0540	Belongs to the ATCase OTCase family
XNRR2_RS27260	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XNRR2_RS27270	COG0505	Belongs to the CarA family
XNRR2_RS27275	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XNRR2_RS27280	COG0167	dihydroorotate dehydrogenase activity
XNRR2_RS27285	COG0284	orotidine-5'-phosphate decarboxylase activity
XNRR2_RS27300	COG1758	RNA polymerase activity
XNRR2_RS27310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XNRR2_RS27345	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XNRR2_RS27360	COG2318	DinB family
XNRR2_RS27365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
XNRR2_RS27370	COG2390	Transcriptional regulator
XNRR2_RS27410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XNRR2_RS27430	COG0697	spore germination
XNRR2_RS27435	COG2233	PERMEase
XNRR2_RS27445	COG0738	Major facilitator superfamily
XNRR2_RS27450	COG1846	Transcriptional regulator
XNRR2_RS27450	COG1940	carbohydrate kinase activity
XNRR2_RS27455	COG1090	epimerase
XNRR2_RS27470	COG3201	nicotinamide mononucleotide transporter
XNRR2_RS27475	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XNRR2_RS27475	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XNRR2_RS27480	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XNRR2_RS27485	COG0140	phosphoribosyl-ATP diphosphatase activity
XNRR2_RS27490	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XNRR2_RS27520	COG1960	acyl-CoA dehydrogenase activity
XNRR2_RS27540	COG0463	Glycosyl transferase, family 2
XNRR2_RS27545	COG3030	protein affecting phage T7 exclusion by the F plasmid
XNRR2_RS27555	COG2270	Major facilitator Superfamily
XNRR2_RS27565	COG2364	Membrane
XNRR2_RS27570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XNRR2_RS27655	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XNRR2_RS27675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XNRR2_RS27685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XNRR2_RS27715	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XNRR2_RS27735	COG1716	ATPase activity
XNRR2_RS27755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XNRR2_RS27765	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XNRR2_RS27765	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XNRR2_RS27805	COG0539	negative regulation of cytoplasmic translation
XNRR2_RS27825	COG0697	spore germination
XNRR2_RS27840	COG0697	spore germination
XNRR2_RS27860	COG4251	negative regulation of phosphorylation
XNRR2_RS27870	COG0154	amidase activity
XNRR2_RS27910	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XNRR2_RS27940	COG0815	Transfers the fatty acyl group on membrane lipoproteins
XNRR2_RS27960	COG1982	Orn Lys Arg decarboxylase major
XNRR2_RS27970	COG1968	undecaprenyl-diphosphatase activity
XNRR2_RS27990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XNRR2_RS28050	COG0110	maltose O-acetyltransferase activity
XNRR2_RS28060	COG1832	CoA-binding protein
XNRR2_RS28065	COG1739	Uncharacterized protein family UPF0029
XNRR2_RS28085	COG1595	DNA-templated transcription, initiation
XNRR2_RS28105	COG0420	3'-5' exonuclease activity
XNRR2_RS28110	COG0419	ATPase involved in DNA repair
XNRR2_RS28115	COG1522	sequence-specific DNA binding
XNRR2_RS28125	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS28140	COG0626	cystathionine gamma-synthase activity
XNRR2_RS28165	COG2188	Transcriptional regulator
XNRR2_RS28170	COG1940	carbohydrate kinase activity
XNRR2_RS28185	COG3663	DNA glycosylase
XNRR2_RS28190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XNRR2_RS28210	COG0456	acetyltransferase
XNRR2_RS28215	COG0488	(ABC) transporter
XNRR2_RS28220	COG0488	(ABC) transporter
XNRR2_RS28230	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XNRR2_RS28235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XNRR2_RS28240	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XNRR2_RS28265	COG0791	NLP P60 protein
XNRR2_RS28270	COG0740	serine-type endopeptidase activity
XNRR2_RS28280	COG0831	urea catabolic process
XNRR2_RS28285	COG0832	Belongs to the urease beta subunit family
XNRR2_RS28290	COG0804	urea catabolic process
XNRR2_RS28300	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XNRR2_RS28305	COG0829	nickel cation binding
XNRR2_RS28310	COG4552	Acetyltransferase involved in intracellular survival and related
XNRR2_RS28315	COG0204	Acyl-transferase
XNRR2_RS28360	COG2175	clavaminate synthase activity
XNRR2_RS28370	COG0435	Glutathione S-transferase
XNRR2_RS28385	COG2208	phosphoserine phosphatase activity
XNRR2_RS28385	COG2770	Histidine kinase
XNRR2_RS28400	COG0205	6-phosphofructokinase activity
XNRR2_RS28405	COG3442	glutamine amidotransferase
XNRR2_RS28415	COG0242	peptide deformylase activity
XNRR2_RS28425	COG1960	acyl-CoA dehydrogenase activity
XNRR2_RS28445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XNRR2_RS28470	COG1175	transmembrane transport
XNRR2_RS28475	COG0395	ABC-type sugar transport system, permease component
XNRR2_RS28480	COG2723	6-phospho-beta-galactosidase activity
XNRR2_RS28485	COG0501	Belongs to the peptidase M48B family
XNRR2_RS28530	COG4251	negative regulation of phosphorylation
XNRR2_RS28535	COG0784	Response regulator, receiver
XNRR2_RS28555	COG0656	L-ascorbic acid biosynthetic process
XNRR2_RS28565	COG1595	DNA-templated transcription, initiation
XNRR2_RS28575	COG1132	(ABC) transporter
XNRR2_RS28595	COG0697	spore germination
XNRR2_RS28600	COG0546	phosphoglycolate phosphatase activity
XNRR2_RS28605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XNRR2_RS28615	COG2313	pseudouridylate synthase activity
XNRR2_RS28620	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
XNRR2_RS28655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XNRR2_RS28660	COG3279	Response regulator of the LytR AlgR family
XNRR2_RS28670	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XNRR2_RS28675	COG3275	phosphorelay sensor kinase activity
XNRR2_RS28740	COG0583	DNA-binding transcription factor activity
XNRR2_RS28750	COG1053	succinate dehydrogenase
XNRR2_RS28755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XNRR2_RS28760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XNRR2_RS28770	COG3360	Dodecin
XNRR2_RS28775	COG2182	Extracellular solute-binding protein
XNRR2_RS28780	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XNRR2_RS28785	COG0121	glutamine amidotransferase
XNRR2_RS28790	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XNRR2_RS28810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XNRR2_RS28815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XNRR2_RS28835	COG2837	iron assimilation
XNRR2_RS28845	COG1796	DNA polymerase
XNRR2_RS28845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
XNRR2_RS28875	COG3293	Transposase
XNRR2_RS28890	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
XNRR2_RS28915	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XNRR2_RS28925	COG0254	rRNA binding
XNRR2_RS28930	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XNRR2_RS28935	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XNRR2_RS28940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XNRR2_RS28970	COG0477	Major facilitator Superfamily
XNRR2_RS29000	COG3119	arylsulfatase activity
XNRR2_RS29020	COG4948	Mandelate Racemase Muconate Lactonizing
XNRR2_RS29090	COG0464	growth
XNRR2_RS29110	COG3655	Transcriptional regulator
XNRR2_RS29130	COG0803	Belongs to the bacterial solute-binding protein 9 family
XNRR2_RS29140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XNRR2_RS29145	COG1121	(ABC) transporter
XNRR2_RS29150	COG0590	tRNA wobble adenosine to inosine editing
XNRR2_RS29155	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XNRR2_RS29185	COG2201	protein-glutamate methylesterase activity
XNRR2_RS29190	COG0300	oxidoreductase activity
XNRR2_RS29200	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XNRR2_RS29235	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
XNRR2_RS29240	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
XNRR2_RS29245	COG1984	allophanate hydrolase subunit 2
XNRR2_RS29275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNRR2_RS29280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNRR2_RS29285	COG1120	ATPase activity
XNRR2_RS29310	COG1132	(ABC) transporter
XNRR2_RS29315	COG1132	(ABC) transporter
XNRR2_RS29320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XNRR2_RS29330	COG0110	maltose O-acetyltransferase activity
XNRR2_RS29345	COG0242	peptide deformylase activity
XNRR2_RS29365	COG1349	DNA-binding transcription factor activity
XNRR2_RS29380	COG3395	kinase activity
XNRR2_RS29385	COG0235	Class ii aldolase
XNRR2_RS29425	COG4608	Belongs to the ABC transporter superfamily
XNRR2_RS29430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XNRR2_RS29445	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS29465	COG1174	glycine betaine transport
XNRR2_RS29470	COG1174	glycine betaine transport
XNRR2_RS29480	COG1125	glycine betaine transport
XNRR2_RS29480	COG0517	IMP dehydrogenase activity
XNRR2_RS29505	COG1960	acyl-CoA dehydrogenase activity
XNRR2_RS29510	COG1960	acyl-CoA dehydrogenase activity
XNRR2_RS29520	COG0601	transmembrane transport
XNRR2_RS29525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XNRR2_RS29530	COG0444	Belongs to the ABC transporter superfamily
XNRR2_RS29535	COG1124	(ABC) transporter
XNRR2_RS29545	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
XNRR2_RS29550	COG2318	DinB family
XNRR2_RS29575	COG0277	FAD linked oxidase domain protein
XNRR2_RS29580	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
XNRR2_RS29590	COG2271	Major facilitator Superfamily
XNRR2_RS29640	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS29735	COG3321	synthase
XNRR2_RS29735	COG0604	alcohol dehydrogenase
XNRR2_RS29735	COG0604	alcohol dehydrogenase
XNRR2_RS29735	COG3321	synthase
XNRR2_RS29755	COG2124	cytochrome p450
XNRR2_RS29760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XNRR2_RS29795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XNRR2_RS29805	COG1129	ABC transporter
XNRR2_RS29840	COG1028	Short-chain dehydrogenase reductase Sdr
XNRR2_RS29845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XNRR2_RS29850	COG2151	metal-sulfur cluster biosynthetic enzyme
XNRR2_RS29855	COG3396	Phenylacetate-CoA oxygenase
XNRR2_RS29865	COG3396	Phenylacetate-CoA oxygenase
XNRR2_RS29880	COG0604	alcohol dehydrogenase
XNRR2_RS29890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XNRR2_RS29940	COG0515	serine threonine protein kinase
XNRR2_RS29975	COG1404	Belongs to the peptidase S8 family
XNRR2_RS30020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XNRR2_RS30020	COG0300	oxidoreductase activity
XNRR2_RS30020	COG4221	oxidoreductase activity
XNRR2_RS30020	COG3321	synthase
XNRR2_RS30025	COG4221	oxidoreductase activity
XNRR2_RS30025	COG3321	synthase
XNRR2_RS30025	COG0300	oxidoreductase activity
XNRR2_RS30025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XNRR2_RS30030	COG4335	DNA alkylation repair
XNRR2_RS30055	COG0477	Major facilitator Superfamily
XNRR2_RS30085	COG3246	L-lysine catabolic process to acetate
XNRR2_RS30090	COG1250	3-hydroxyacyl-CoA dehydrogenase