locus-tag	class	description
FE156_RS00040	COG0477	Major facilitator Superfamily
FE156_RS00065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FE156_RS00070	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FE156_RS00075	COG2080	2 iron, 2 sulfur cluster binding
FE156_RS00085	COG2197	response regulator
FE156_RS00095	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FE156_RS00115	COG0477	Major facilitator Superfamily
FE156_RS00170	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FE156_RS00170	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE156_RS00220	COG4608	Belongs to the ABC transporter superfamily
FE156_RS00225	COG0444	Belongs to the ABC transporter superfamily
FE156_RS00235	COG0601	transmembrane transport
FE156_RS00240	COG0747	negative chemotaxis
FE156_RS00250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FE156_RS00315	COG0277	FAD linked oxidase domain protein
FE156_RS00365	COG0589	response to stress
FE156_RS00370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FE156_RS00375	COG2813	Specifically methylates the guanine in position
FE156_RS00385	COG2356	endonuclease I
FE156_RS00450	COG3547	Transposase (IS116 IS110 IS902 family)
FE156_RS00470	COG0713	ATP synthesis coupled electron transport
FE156_RS00480	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FE156_RS00490	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE156_RS00505	COG4733	cellulase activity
FE156_RS00505	COG5297	Belongs to the glycosyl hydrolase family 6
FE156_RS00525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FE156_RS00560	COG0475	glutathione-regulated potassium exporter activity
FE156_RS00580	COG2197	response regulator
FE156_RS00595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FE156_RS00610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FE156_RS00620	COG0640	Transcriptional regulator
FE156_RS00655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE156_RS00660	COG2192	nodulation
FE156_RS00685	COG0297	glycogen (starch) synthase activity
FE156_RS00700	COG0859	PFAM glycosyl transferase family 9
FE156_RS00715	COG1482	cell wall glycoprotein biosynthetic process
FE156_RS00720	COG0477	Major facilitator Superfamily
FE156_RS00735	COG0328	RNA-DNA hybrid ribonuclease activity
FE156_RS00740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE156_RS00745	COG0431	NADPH-dependent FMN reductase
FE156_RS00775	COG1595	DNA-templated transcription, initiation
FE156_RS00805	COG0667	Aldo Keto reductase
FE156_RS00830	COG0726	polysaccharide deacetylase
FE156_RS00835	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS00845	COG1131	(ABC) transporter
FE156_RS00865	COG0326	Molecular chaperone. Has ATPase activity
FE156_RS00895	COG0346	lactoylglutathione lyase activity
FE156_RS00900	COG0640	Transcriptional regulator
FE156_RS00915	COG1120	ATPase activity
FE156_RS00955	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE156_RS00990	COG1349	DNA-binding transcription factor activity
FE156_RS01000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE156_RS01000	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FE156_RS01000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE156_RS01005	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE156_RS01005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FE156_RS01030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FE156_RS01050	COG2226	methyltransferase
FE156_RS01095	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS01110	COG0513	Belongs to the DEAD box helicase family
FE156_RS01120	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FE156_RS01135	COG3217	Mosc domain protein beta barrel domain protein
FE156_RS01135	COG0633	Ferredoxin
FE156_RS01155	COG1349	DNA-binding transcription factor activity
FE156_RS01175	COG1940	carbohydrate kinase activity
FE156_RS01185	COG2223	nitrite transmembrane transporter activity
FE156_RS01200	COG2197	response regulator
FE156_RS01215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FE156_RS01230	COG1609	Transcriptional regulator
FE156_RS01245	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FE156_RS01290	COG0584	glycerophosphoryl diester phosphodiesterase
FE156_RS01305	COG1846	Transcriptional regulator
FE156_RS01325	COG0671	phosphoesterase, PA-phosphatase related
FE156_RS01355	COG2233	PERMEase
FE156_RS01360	COG0640	Transcriptional regulator
FE156_RS01365	COG1902	pentaerythritol trinitrate reductase activity
FE156_RS01390	COG0586	Pfam SNARE associated Golgi protein
FE156_RS01395	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FE156_RS01425	COG0071	Belongs to the small heat shock protein (HSP20) family
FE156_RS01435	COG0243	molybdopterin cofactor binding
FE156_RS01470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FE156_RS01490	COG2814	Major facilitator Superfamily
FE156_RS01520	COG1309	transcriptional regulator
FE156_RS01540	COG0395	ABC-type sugar transport system, permease component
FE156_RS01545	COG1175	transmembrane transport
FE156_RS01555	COG1609	Transcriptional regulator
FE156_RS01560	COG0432	Pfam Uncharacterised protein family UPF0047
FE156_RS01565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FE156_RS01570	COG1116	anion transmembrane transporter activity
FE156_RS01580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE156_RS01595	COG1132	(ABC) transporter
FE156_RS01635	COG1946	Acyl-CoA thioesterase
FE156_RS01650	COG2018	Roadblock/LC7 domain
FE156_RS01695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FE156_RS01720	COG1070	Carbohydrate kinase
FE156_RS01735	COG2124	cytochrome p450
FE156_RS01740	COG2130	NADP-dependent
FE156_RS01745	COG1233	COG1233 Phytoene dehydrogenase and related
FE156_RS01820	COG0477	Major facilitator Superfamily
FE156_RS01830	COG0583	DNA-binding transcription factor activity
FE156_RS01835	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FE156_RS01840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FE156_RS01850	COG1960	acyl-CoA dehydrogenase activity
FE156_RS01855	COG2391	methyltransferase activity
FE156_RS01900	COG1396	sequence-specific DNA binding
FE156_RS01905	COG0740	serine-type endopeptidase activity
FE156_RS01910	COG0740	serine-type endopeptidase activity
FE156_RS01960	COG3959	Transketolase, thiamine diphosphate binding domain
FE156_RS01965	COG3958	Transketolase
FE156_RS02040	COG2755	lipolytic protein G-D-S-L family
FE156_RS02045	COG2365	Tyrosine phosphatase family
FE156_RS02075	COG1657	PFAM Prenyltransferase squalene oxidase
FE156_RS02085	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FE156_RS02100	COG1388	LysM domain
FE156_RS02100	COG1134	teichoic acid transport
FE156_RS02125	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FE156_RS02140	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FE156_RS02155	COG1162	GTPase activity
FE156_RS02200	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FE156_RS02225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FE156_RS02230	COG0789	Transcriptional regulator
FE156_RS02235	COG1024	Enoyl-CoA hydratase
FE156_RS02235	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE156_RS02240	COG0183	Belongs to the thiolase family
FE156_RS02245	COG1960	acyl-CoA dehydrogenase activity
FE156_RS02250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FE156_RS02260	COG1515	deoxyribonuclease V activity
FE156_RS02280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE156_RS02290	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE156_RS02290	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE156_RS02300	COG0488	(ABC) transporter
FE156_RS02320	COG2197	response regulator
FE156_RS02335	COG0438	transferase activity, transferring glycosyl groups
FE156_RS02370	COG0254	rRNA binding
FE156_RS02380	COG1793	dna ligase
FE156_RS02385	COG1024	Enoyl-CoA hydratase
FE156_RS02420	COG0789	Transcriptional regulator
FE156_RS02445	COG2319	Wd-40 repeat
FE156_RS02445	COG4249	Peptidase C14 caspase catalytic subunit p20
FE156_RS02475	COG2274	protein secretion by the type I secretion system
FE156_RS02480	COG1846	Transcriptional regulator
FE156_RS02520	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS02565	COG2814	Major facilitator Superfamily
FE156_RS02570	COG2259	Doxx family
FE156_RS02580	COG1869	D-ribose catabolic process
FE156_RS02585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE156_RS02595	COG1129	ABC transporter
FE156_RS02600	COG1609	Transcriptional regulator
FE156_RS02695	COG1172	Belongs to the binding-protein-dependent transport system permease family
FE156_RS02700	COG1129	ABC transporter
FE156_RS02705	COG1940	carbohydrate kinase activity
FE156_RS02710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FE156_RS02720	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FE156_RS02730	COG0583	DNA-binding transcription factor activity
FE156_RS02760	COG2154	pterin-4-alpha-carbinolamine dehydratase
FE156_RS02790	COG1140	nitrate reductase beta subunit
FE156_RS02855	COG0693	protein deglycase activity
FE156_RS02865	COG1597	lipid kinase activity
FE156_RS02870	COG4106	trans-aconitate 2-methyltransferase activity
FE156_RS02885	COG3226	Transcriptional regulator
FE156_RS02910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FE156_RS02930	COG1619	proteins homologs of microcin C7 resistance protein MccF
FE156_RS02940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FE156_RS03005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE156_RS03010	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE156_RS03015	COG1120	ATPase activity
FE156_RS03020	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE156_RS03030	COG0604	alcohol dehydrogenase
FE156_RS03035	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FE156_RS03035	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FE156_RS03040	COG2301	Belongs to the HpcH HpaI aldolase family
FE156_RS03055	COG0688	phosphatidylethanolamine metabolic process
FE156_RS03065	COG1929	Belongs to the glycerate kinase type-1 family
FE156_RS03070	COG0488	(ABC) transporter
FE156_RS03080	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FE156_RS03100	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FE156_RS03125	COG0159	tryptophan synthase activity
FE156_RS03140	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FE156_RS03155	COG0483	inositol monophosphate 1-phosphatase activity
FE156_RS03165	COG0095	Lipoate-protein ligase
FE156_RS03185	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FE156_RS03240	COG0765	amino acid transport
FE156_RS03245	COG0765	amino acid transport
FE156_RS03250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE156_RS03255	COG1126	abc transporter atp-binding protein
FE156_RS03290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FE156_RS03325	COG5183	chlorophyll binding
FE156_RS03325	COG2133	pyrroloquinoline quinone binding
FE156_RS03330	COG1132	(ABC) transporter
FE156_RS03335	COG1132	(ABC) transporter
FE156_RS03385	COG0464	growth
FE156_RS03485	COG1940	carbohydrate kinase activity
FE156_RS03495	COG1172	Belongs to the binding-protein-dependent transport system permease family
FE156_RS03505	COG2188	Transcriptional regulator
FE156_RS03510	COG0673	inositol 2-dehydrogenase activity
FE156_RS03535	COG4585	Histidine kinase
FE156_RS03550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FE156_RS03555	COG1414	Transcriptional regulator
FE156_RS03570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FE156_RS03575	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FE156_RS03580	COG2080	2 iron, 2 sulfur cluster binding
FE156_RS03585	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FE156_RS03600	COG4941	Belongs to the sigma-70 factor family
FE156_RS03605	COG3795	YCII-related domain
FE156_RS03610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE156_RS03610	COG0723	plastoquinol--plastocyanin reductase activity
FE156_RS03620	COG1621	beta-fructofuranosidase activity
FE156_RS03625	COG1609	Transcriptional regulator
FE156_RS03640	COG1609	Transcriptional regulator
FE156_RS03690	COG2233	PERMEase
FE156_RS03705	COG2351	hydroxyisourate hydrolase activity
FE156_RS03725	COG3622	Belongs to the hyi family
FE156_RS03730	COG2084	Dehydrogenase
FE156_RS03735	COG0753	catalase activity
FE156_RS03760	COG3960	tartronate-semialdehyde synthase activity
FE156_RS03770	COG0318	PFAM AMP-dependent synthetase and ligase
FE156_RS03775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FE156_RS03790	COG1309	transcriptional regulator
FE156_RS03835	COG2252	PERMEase
FE156_RS03840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FE156_RS03855	COG3835	regulator
FE156_RS03860	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FE156_RS03890	COG0028	Belongs to the TPP enzyme family
FE156_RS03910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FE156_RS03915	COG1162	GTPase activity
FE156_RS03920	COG2124	cytochrome p450
FE156_RS03960	COG0583	DNA-binding transcription factor activity
FE156_RS03980	COG1595	DNA-templated transcription, initiation
FE156_RS04000	COG0702	epimerase
FE156_RS04005	COG1846	Transcriptional regulator
FE156_RS04010	COG2409	Drug exporters of the RND superfamily
FE156_RS04020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE156_RS04025	COG1120	ATPase activity
FE156_RS04040	COG1309	transcriptional regulator
FE156_RS04050	COG2255	four-way junction helicase activity
FE156_RS04075	COG2040	homocysteine
FE156_RS04095	COG1960	acyl-CoA dehydrogenase activity
FE156_RS04100	COG0604	alcohol dehydrogenase
FE156_RS04125	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE156_RS04135	COG0175	sulfate reduction
FE156_RS04140	COG0529	Catalyzes the synthesis of activated sulfate
FE156_RS04165	COG1116	anion transmembrane transporter activity
FE156_RS04170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FE156_RS04185	COG0386	Belongs to the glutathione peroxidase family
FE156_RS04190	COG1064	alcohol dehydrogenase
FE156_RS04195	COG1309	transcriptional regulator
FE156_RS04230	COG2176	DNA-directed DNA polymerase activity
FE156_RS04230	COG5002	protein histidine kinase activity
FE156_RS04300	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FE156_RS04305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FE156_RS04325	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FE156_RS04355	COG3220	belongs to the UPF0276 family
FE156_RS04365	COG3253	May function as heme-dependent peroxidase
FE156_RS04370	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FE156_RS04385	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FE156_RS04405	COG0183	Belongs to the thiolase family
FE156_RS04410	COG1024	Enoyl-CoA hydratase
FE156_RS04410	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE156_RS04430	COG0531	amino acid
FE156_RS04435	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FE156_RS04440	COG4214	carbohydrate transport
FE156_RS04450	COG4213	ABC transporter substrate-binding protein
FE156_RS04460	COG0395	ABC-type sugar transport system, permease component
FE156_RS04465	COG1175	transmembrane transport
FE156_RS04470	COG1653	transport
FE156_RS04500	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FE156_RS04505	COG0515	serine threonine protein kinase
FE156_RS04505	COG2815	serine threonine protein kinase
FE156_RS04555	COG0443	Heat shock 70 kDa protein
FE156_RS04580	COG1401	restriction endodeoxyribonuclease activity
FE156_RS04590	COG0210	DNA helicase
FE156_RS04640	COG2235	arginine
FE156_RS04660	COG0651	ATP synthesis coupled electron transport
FE156_RS04670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FE156_RS04670	COG2111	Na H antiporter
FE156_RS04680	COG2124	cytochrome p450
FE156_RS04710	COG0531	amino acid
FE156_RS04715	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FE156_RS04720	COG2235	arginine
FE156_RS04730	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FE156_RS04765	COG1799	cell septum assembly
FE156_RS04775	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FE156_RS04790	COG1556	Lactate utilization protein
FE156_RS04795	COG1139	Iron-sulfur cluster binding protein
FE156_RS04800	COG0247	lactate metabolic process
FE156_RS04805	COG1620	l-lactate permease
FE156_RS04855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FE156_RS04865	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FE156_RS04875	COG0477	Major facilitator Superfamily
FE156_RS04880	COG1120	ATPase activity
FE156_RS04885	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE156_RS04890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE156_RS04910	COG1819	glycosyl
FE156_RS04930	COG1309	transcriptional regulator
FE156_RS04945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE156_RS04960	COG2936	dipeptidyl-peptidase activity
FE156_RS04975	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS04990	COG2050	protein possibly involved in aromatic compounds catabolism
FE156_RS05005	COG0789	Transcriptional regulator
FE156_RS05105	COG0438	transferase activity, transferring glycosyl groups
FE156_RS05110	COG3226	Transcriptional regulator
FE156_RS05115	COG0738	Major facilitator superfamily
FE156_RS05130	COG4213	ABC transporter substrate-binding protein
FE156_RS05135	COG1172	Belongs to the binding-protein-dependent transport system permease family
FE156_RS05140	COG1172	Belongs to the binding-protein-dependent transport system permease family
FE156_RS05145	COG1129	ABC transporter
FE156_RS05155	COG0252	asparaginase activity
FE156_RS05195	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FE156_RS05205	COG0473	3-isopropylmalate dehydrogenase activity
FE156_RS05220	COG0656	L-ascorbic acid biosynthetic process
FE156_RS05255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FE156_RS05280	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FE156_RS05290	COG1127	ABC transporter
FE156_RS05380	COG0395	ABC-type sugar transport system, permease component
FE156_RS05385	COG1063	alcohol dehydrogenase
FE156_RS05420	COG0531	amino acid
FE156_RS05425	COG0569	domain protein
FE156_RS05455	COG1136	(ABC) transporter
FE156_RS05475	COG0756	dUTP diphosphatase activity
FE156_RS05500	COG2205	protein histidine kinase activity
FE156_RS05505	COG0745	RESPONSE REGULATOR receiver
FE156_RS05510	COG0483	inositol monophosphate 1-phosphatase activity
FE156_RS05515	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FE156_RS05565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE156_RS05590	COG0612	Peptidase, M16
FE156_RS05595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FE156_RS05610	COG0395	ABC-type sugar transport system, permease component
FE156_RS05615	COG1175	transmembrane transport
FE156_RS05635	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE156_RS05645	COG0210	DNA helicase
FE156_RS05670	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FE156_RS05675	COG1802	Transcriptional regulator
FE156_RS05720	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FE156_RS05735	COG0588	phosphoglycerate mutase activity
FE156_RS05760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FE156_RS05765	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FE156_RS05770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FE156_RS05810	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FE156_RS05820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE156_RS05825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FE156_RS05835	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FE156_RS05855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FE156_RS05860	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FE156_RS05865	COG2205	protein histidine kinase activity
FE156_RS05875	COG1126	abc transporter atp-binding protein
FE156_RS05880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE156_RS05885	COG0765	amino acid transport
FE156_RS05890	COG0765	amino acid transport
FE156_RS05920	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FE156_RS05950	COG0628	permease
FE156_RS05975	COG1201	RNA secondary structure unwinding
FE156_RS05980	COG0596	Alpha beta hydrolase
FE156_RS06000	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FE156_RS06010	COG0783	Belongs to the Dps family
FE156_RS06015	COG1396	sequence-specific DNA binding
FE156_RS06020	COG1058	Belongs to the CinA family
FE156_RS06020	COG1546	Belongs to the CinA family
FE156_RS06030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FE156_RS06040	COG1674	ftsk spoiiie
FE156_RS06050	COG3850	Histidine kinase
FE156_RS06050	COG3437	response regulator, receiver
FE156_RS06050	COG4999	Histidine kinase
FE156_RS06050	COG2205	protein histidine kinase activity
FE156_RS06060	COG2208	phosphoserine phosphatase activity
FE156_RS06060	COG2770	Histidine kinase
FE156_RS06095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FE156_RS06100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE156_RS06105	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FE156_RS06125	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FE156_RS06130	COG0612	Peptidase, M16
FE156_RS06135	COG1185	polyribonucleotide nucleotidyltransferase activity
FE156_RS06140	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FE156_RS06155	COG0747	negative chemotaxis
FE156_RS06160	COG0601	transmembrane transport
FE156_RS06165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE156_RS06175	COG4608	Belongs to the ABC transporter superfamily
FE156_RS06180	COG1357	PFAM Pentapeptide repeats (8 copies)
FE156_RS06215	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FE156_RS06220	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FE156_RS06230	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FE156_RS06245	COG0779	Required for maturation of 30S ribosomal subunits
FE156_RS06265	COG0442	prolyl-tRNA aminoacylation
FE156_RS06285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE156_RS06290	COG0601	transmembrane transport
FE156_RS06310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FE156_RS06315	COG0750	zinc metalloprotease
FE156_RS06320	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FE156_RS06330	COG1940	carbohydrate kinase activity
FE156_RS06335	COG1012	belongs to the aldehyde dehydrogenase family
FE156_RS06340	COG2508	Transcriptional regulator
FE156_RS06340	COG2508	Transcriptional regulator
FE156_RS06370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE156_RS06375	COG1177	transmembrane transport
FE156_RS06385	COG3842	ATPase activity
FE156_RS06395	COG1012	belongs to the aldehyde dehydrogenase family
FE156_RS06410	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FE156_RS06430	COG1012	belongs to the aldehyde dehydrogenase family
FE156_RS06440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FE156_RS06445	COG1136	(ABC) transporter
FE156_RS06465	COG3842	ATPase activity
FE156_RS06470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FE156_RS06480	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FE156_RS06490	COG0233	cytoplasmic translational termination
FE156_RS06495	COG0528	UMP kinase activity
FE156_RS06500	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FE156_RS06505	COG0052	Belongs to the universal ribosomal protein uS2 family
FE156_RS06520	COG1191	sigma factor activity
FE156_RS06535	COG0792	nuclease activity
FE156_RS06550	COG0681	Belongs to the peptidase S26 family
FE156_RS06555	COG0681	Belongs to the peptidase S26 family
FE156_RS06570	COG0335	large ribosomal subunit rRNA binding
FE156_RS06575	COG0336	Belongs to the RNA methyltransferase TrmD family
FE156_RS06580	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FE156_RS06585	COG1837	Belongs to the UPF0109 family
FE156_RS06590	COG0228	four-way junction DNA binding
FE156_RS06615	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FE156_RS06645	COG0477	Major facilitator Superfamily
FE156_RS06650	COG1196	nuclear chromosome segregation
FE156_RS06670	COG2340	Cysteine-rich secretory protein family
FE156_RS06675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FE156_RS06680	COG0571	ribonuclease III activity
FE156_RS06685	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FE156_RS06700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FE156_RS06705	COG0742	ribosomal rna small subunit methyltransferase
FE156_RS06720	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FE156_RS06745	COG1181	Belongs to the D-alanine--D-alanine ligase family
FE156_RS06750	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FE156_RS06760	COG1920	GTP binding
FE156_RS06770	COG0776	regulation of translation
FE156_RS06780	COG0066	3-isopropylmalate dehydratase activity
FE156_RS06785	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FE156_RS06790	COG1414	Transcriptional regulator
FE156_RS06835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FE156_RS06840	COG0179	Fumarylacetoacetate (FAA) hydrolase
FE156_RS06875	COG2018	Roadblock/LC7 domain
FE156_RS06895	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FE156_RS06905	COG2353	YceI-like domain
FE156_RS06950	COG0789	Transcriptional regulator
FE156_RS06990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FE156_RS07010	COG0804	urea catabolic process
FE156_RS07015	COG0831	urea catabolic process
FE156_RS07015	COG0832	Belongs to the urease beta subunit family
FE156_RS07020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FE156_RS07035	COG0575	Belongs to the CDS family
FE156_RS07050	COG1012	belongs to the aldehyde dehydrogenase family
FE156_RS07055	COG0506	proline dehydrogenase activity
FE156_RS07060	COG3835	regulator
FE156_RS07080	COG2890	protein-(glutamine-N5) methyltransferase activity
FE156_RS07095	COG0440	acetolactate synthase activity
FE156_RS07115	COG0667	Aldo Keto reductase
FE156_RS07140	COG2409	Drug exporters of the RND superfamily
FE156_RS07145	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FE156_RS07155	COG0154	amidase activity
FE156_RS07165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FE156_RS07175	COG4221	oxidoreductase activity
FE156_RS07195	COG0482	sulfurtransferase activity
FE156_RS07220	COG2860	membrane
FE156_RS07225	COG4608	Belongs to the ABC transporter superfamily
FE156_RS07230	COG0444	Belongs to the ABC transporter superfamily
FE156_RS07240	COG0601	transmembrane transport
FE156_RS07245	COG4166	transmembrane transport
FE156_RS07270	COG0509	glycine decarboxylation via glycine cleavage system
FE156_RS07275	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FE156_RS07280	COG1760	l-serine dehydratase
FE156_RS07310	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FE156_RS07315	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FE156_RS07320	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FE156_RS07335	COG0477	Major facilitator Superfamily
FE156_RS07350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE156_RS07375	COG2085	NADP oxidoreductase coenzyme F420-dependent
FE156_RS07405	COG1376	ErfK ybiS ycfS ynhG family protein
FE156_RS07425	COG1131	(ABC) transporter
FE156_RS07430	COG1132	(ABC) transporter
FE156_RS07435	COG1132	(ABC) transporter
FE156_RS07455	COG0366	Alpha amylase catalytic
FE156_RS07460	COG0366	Alpha amylase catalytic
FE156_RS07465	COG3281	Trehalose synthase
FE156_RS07470	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FE156_RS07485	COG1119	ATPase activity
FE156_RS07505	COG1301	dicarboxylic acid transport
FE156_RS07510	COG3290	protein histidine kinase activity
FE156_RS07515	COG4565	transcriptional regulatory protein
FE156_RS07520	COG0205	6-phosphofructokinase activity
FE156_RS07525	COG0280	phosphate acetyltransferase
FE156_RS07525	COG0857	belongs to the CobB CobQ family
FE156_RS07530	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FE156_RS07575	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FE156_RS07575	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FE156_RS07640	COG1335	isochorismatase
FE156_RS07680	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FE156_RS07685	COG0830	nickel cation binding
FE156_RS07690	COG0804	urea catabolic process
FE156_RS07695	COG0832	Belongs to the urease beta subunit family
FE156_RS07695	COG0831	urea catabolic process
FE156_RS07705	COG0831	urea catabolic process
FE156_RS07715	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FE156_RS07720	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FE156_RS07735	COG0183	Belongs to the thiolase family
FE156_RS07755	COG1131	(ABC) transporter
FE156_RS07790	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FE156_RS07805	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE156_RS07820	COG4585	Histidine kinase
FE156_RS07825	COG2197	response regulator
FE156_RS07845	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FE156_RS07850	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FE156_RS07855	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FE156_RS07860	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FE156_RS07865	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FE156_RS07870	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FE156_RS07875	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FE156_RS07890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FE156_RS07895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FE156_RS07905	COG2890	protein-(glutamine-N5) methyltransferase activity
FE156_RS07910	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FE156_RS07915	COG0254	rRNA binding
FE156_RS07920	COG1316	TRANSCRIPTIONal
FE156_RS07930	COG0083	homoserine kinase activity
FE156_RS07935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FE156_RS07940	COG0460	homoserine dehydrogenase
FE156_RS07945	COG0019	diaminopimelate decarboxylase activity
FE156_RS07950	COG0018	arginyl-trna synthetase
FE156_RS07985	COG1012	belongs to the aldehyde dehydrogenase family
FE156_RS07995	COG1191	sigma factor activity
FE156_RS08000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FE156_RS08000	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FE156_RS08010	COG2267	carboxylic ester hydrolase activity
FE156_RS08015	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FE156_RS08020	COG3285	dna ligase
FE156_RS08020	COG1793	dna ligase
FE156_RS08030	COG0772	Belongs to the SEDS family
FE156_RS08110	COG0726	polysaccharide deacetylase
FE156_RS08115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FE156_RS08120	COG0477	Major facilitator Superfamily
FE156_RS08135	COG1595	DNA-templated transcription, initiation
FE156_RS08145	COG1131	(ABC) transporter
FE156_RS08165	COG0745	RESPONSE REGULATOR receiver
FE156_RS08175	COG0567	Dehydrogenase, E1 component
FE156_RS08175	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE156_RS08205	COG2255	four-way junction helicase activity
FE156_RS08245	COG0604	alcohol dehydrogenase
FE156_RS08250	COG0281	malic enzyme
FE156_RS08260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE156_RS08270	COG1126	abc transporter atp-binding protein
FE156_RS08275	COG4106	trans-aconitate 2-methyltransferase activity
FE156_RS08300	COG0789	Transcriptional regulator
FE156_RS08325	COG0142	geranyltranstransferase activity
FE156_RS08335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FE156_RS08340	COG1959	2 iron, 2 sulfur cluster binding
FE156_RS08360	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FE156_RS08375	COG2172	sigma factor antagonist activity
FE156_RS08390	COG1597	lipid kinase activity
FE156_RS08405	COG0363	glucosamine-6-phosphate deaminase activity
FE156_RS08410	COG1472	Belongs to the glycosyl hydrolase 3 family
FE156_RS08415	COG0395	ABC-type sugar transport system, permease component
FE156_RS08420	COG1175	transmembrane transport
FE156_RS08425	COG2182	Extracellular solute-binding protein
FE156_RS08430	COG2188	Transcriptional regulator
FE156_RS08435	COG1966	Carbon starvation protein
FE156_RS08455	COG2124	cytochrome p450
FE156_RS08465	COG0242	peptide deformylase activity
FE156_RS08475	COG5662	AntiSigma factor
FE156_RS08480	COG1595	DNA-templated transcription, initiation
FE156_RS08500	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FE156_RS08510	COG2076	Multidrug Resistance protein
FE156_RS08520	COG0483	inositol monophosphate 1-phosphatase activity
FE156_RS08525	COG0753	catalase activity
FE156_RS08550	COG1615	UPF0182 protein
FE156_RS08560	COG3480	Lon protease (S16) C-terminal proteolytic domain
FE156_RS08655	COG0210	DNA helicase
FE156_RS08750	COG0513	Belongs to the DEAD box helicase family
FE156_RS08760	COG1432	Conserved Protein
FE156_RS08765	COG2095	MarC family integral membrane protein
FE156_RS08770	COG0613	PHP domain protein
FE156_RS08775	COG2814	Major facilitator Superfamily
FE156_RS08785	COG0598	Magnesium transport protein CorA
FE156_RS08825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FE156_RS08845	COG1595	DNA-templated transcription, initiation
FE156_RS08860	COG1024	Enoyl-CoA hydratase
FE156_RS08870	COG0519	Catalyzes the synthesis of GMP from XMP
FE156_RS08895	COG2207	Transcriptional regulator
FE156_RS08900	COG1611	Belongs to the LOG family
FE156_RS08905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FE156_RS08940	COG2912	Transglutaminase-like superfamily
FE156_RS08955	COG1172	Belongs to the binding-protein-dependent transport system permease family
FE156_RS08965	COG1129	ABC transporter
FE156_RS08970	COG1879	ABC-type sugar transport system periplasmic component
FE156_RS08975	COG3250	beta-galactosidase activity
FE156_RS08995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FE156_RS09020	COG4608	Belongs to the ABC transporter superfamily
FE156_RS09030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE156_RS09035	COG0601	transmembrane transport
FE156_RS09045	COG4608	Belongs to the ABC transporter superfamily
FE156_RS09050	COG0444	Belongs to the ABC transporter superfamily
FE156_RS09055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE156_RS09060	COG0601	transmembrane transport
FE156_RS09125	COG1554	hydrolase, family 65, central catalytic
FE156_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS09180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE156_RS09190	COG3473	Maleate cis-trans isomerase
FE156_RS09195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FE156_RS09210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE156_RS09215	COG0765	amino acid transport
FE156_RS09220	COG0765	amino acid transport
FE156_RS09225	COG1126	abc transporter atp-binding protein
FE156_RS09255	COG3397	chitin binding
FE156_RS09315	COG0179	Fumarylacetoacetate (FAA) hydrolase
FE156_RS09320	COG0706	membrane insertase activity
FE156_RS09360	COG2733	membrane
FE156_RS09390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FE156_RS09400	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FE156_RS09425	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FE156_RS09435	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FE156_RS09440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FE156_RS09445	COG1263	PTS System
FE156_RS09455	COG1234	tRNA 3'-trailer cleavage
FE156_RS09475	COG1113	amino acid transport
FE156_RS09490	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FE156_RS09500	COG1335	isochorismatase
FE156_RS09535	COG0277	FAD linked oxidase domain protein
FE156_RS09545	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FE156_RS09555	COG1174	glycine betaine transport
FE156_RS09560	COG0517	IMP dehydrogenase activity
FE156_RS09560	COG1125	glycine betaine transport
FE156_RS09565	COG1174	glycine betaine transport
FE156_RS09615	COG2318	DinB family
FE156_RS09640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FE156_RS09645	COG2318	DinB family
FE156_RS09660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FE156_RS09675	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE156_RS09680	COG0395	ABC-type sugar transport system, permease component
FE156_RS09685	COG1175	transmembrane transport
FE156_RS09695	COG3547	Transposase (IS116 IS110 IS902 family)
FE156_RS09710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FE156_RS09715	COG0776	regulation of translation
FE156_RS09725	COG3973	AAA domain
FE156_RS09725	COG3973	AAA domain
FE156_RS09770	COG0583	DNA-binding transcription factor activity
FE156_RS09785	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FE156_RS09790	COG0793	Belongs to the peptidase S41A family
FE156_RS09800	COG2884	Cell division ATP-binding protein ftsE
FE156_RS09815	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FE156_RS09820	COG0515	serine threonine protein kinase
FE156_RS09825	COG0515	serine threonine protein kinase
FE156_RS09830	COG1716	ATPase activity
FE156_RS09835	COG1653	transport
FE156_RS09840	COG1175	transmembrane transport
FE156_RS09845	COG0395	ABC-type sugar transport system, permease component
FE156_RS09850	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FE156_RS09855	COG0438	transferase activity, transferring glycosyl groups
FE156_RS09860	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FE156_RS09875	COG2226	methyltransferase
FE156_RS09890	COG2902	Dehydrogenase
FE156_RS09910	COG0583	DNA-binding transcription factor activity
FE156_RS09920	COG0653	protein targeting
FE156_RS09925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FE156_RS09930	COG3214	Protein conserved in bacteria
FE156_RS09935	COG2197	response regulator
FE156_RS09940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FE156_RS09955	COG5002	protein histidine kinase activity
FE156_RS09960	COG0745	RESPONSE REGULATOR receiver
FE156_RS09965	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FE156_RS09985	COG0714	Associated with various cellular activities
FE156_RS09990	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FE156_RS10030	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FE156_RS10040	COG1482	cell wall glycoprotein biosynthetic process
FE156_RS10050	COG2835	tetraacyldisaccharide 4'-kinase activity
FE156_RS10070	COG1620	l-lactate permease
FE156_RS10110	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FE156_RS10150	COG1316	TRANSCRIPTIONal
FE156_RS10170	COG1316	TRANSCRIPTIONal
FE156_RS10210	COG0753	catalase activity
FE156_RS10240	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FE156_RS10245	COG2197	response regulator
FE156_RS10250	COG4585	Histidine kinase
FE156_RS10255	COG0577	efflux transmembrane transporter activity
FE156_RS10255	COG1136	(ABC) transporter
FE156_RS10270	COG2072	flavoprotein involved in K transport
FE156_RS10310	COG2205	protein histidine kinase activity
FE156_RS10315	COG0745	RESPONSE REGULATOR receiver
FE156_RS10320	COG3104	oligopeptide transport
FE156_RS10335	COG1366	Belongs to the anti-sigma-factor antagonist family
FE156_RS10340	COG1191	sigma factor activity
FE156_RS10345	COG1228	amidohydrolase
FE156_RS10375	COG0395	ABC-type sugar transport system, permease component
FE156_RS10445	COG2755	lipolytic protein G-D-S-L family
FE156_RS10450	COG0183	Belongs to the thiolase family
FE156_RS10475	COG1476	TRANSCRIPTIONal
FE156_RS10490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FE156_RS10500	COG1136	(ABC) transporter
FE156_RS10505	COG1136	(ABC) transporter
FE156_RS10505	COG0577	efflux transmembrane transporter activity
FE156_RS10515	COG1252	NADH dehydrogenase
FE156_RS10550	COG0148	phosphopyruvate hydratase activity
FE156_RS10565	COG2124	cytochrome p450
FE156_RS10615	COG3547	Transposase (IS116 IS110 IS902 family)
FE156_RS10620	COG1733	regulation of RNA biosynthetic process
FE156_RS10640	COG0667	Aldo Keto reductase
FE156_RS10675	COG0154	amidase activity
FE156_RS10680	COG3226	Transcriptional regulator
FE156_RS10690	COG1473	amidohydrolase
FE156_RS10745	COG3903	Transcriptional regulator
FE156_RS10745	COG3629	intracellular signal transduction
FE156_RS10795	COG2267	carboxylic ester hydrolase activity
FE156_RS10850	COG4585	Histidine kinase
FE156_RS10860	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FE156_RS10865	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FE156_RS10885	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FE156_RS10890	COG0193	aminoacyl-tRNA hydrolase activity
FE156_RS10905	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FE156_RS10920	COG4106	trans-aconitate 2-methyltransferase activity
FE156_RS10930	COG2197	response regulator
FE156_RS10935	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FE156_RS10980	COG0488	(ABC) transporter
FE156_RS10985	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FE156_RS10990	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FE156_RS10995	COG0084	hydrolase, TatD family'
FE156_RS11065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FE156_RS11075	COG2409	Drug exporters of the RND superfamily
FE156_RS11095	COG4221	oxidoreductase activity
FE156_RS11105	COG2072	flavoprotein involved in K transport
FE156_RS11115	COG0708	Exodeoxyribonuclease III
FE156_RS11145	COG2197	response regulator
FE156_RS11180	COG0315	cyclic pyranopterin monophosphate synthase activity
FE156_RS11190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FE156_RS11195	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FE156_RS11205	COG3263	regulation of cellular component size
FE156_RS11230	COG1970	mechanosensitive ion channel activity
FE156_RS11250	COG3191	aminopeptidase activity
FE156_RS11280	COG1846	Transcriptional regulator
FE156_RS11335	COG2050	protein possibly involved in aromatic compounds catabolism
FE156_RS11345	COG0183	Belongs to the thiolase family
FE156_RS11350	COG1024	Enoyl-CoA hydratase
FE156_RS11355	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE156_RS11360	COG3396	Phenylacetate-CoA oxygenase
FE156_RS11365	COG3460	Phenylacetate-CoA oxygenase
FE156_RS11370	COG3396	Phenylacetate-CoA oxygenase
FE156_RS11375	COG2151	metal-sulfur cluster biosynthetic enzyme
FE156_RS11420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FE156_RS11425	COG0191	fructose-bisphosphate aldolase activity
FE156_RS11455	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FE156_RS11485	COG0515	serine threonine protein kinase
FE156_RS11485	COG2815	serine threonine protein kinase
FE156_RS11500	COG1278	Cold shock
FE156_RS11580	COG5297	Belongs to the glycosyl hydrolase family 6
FE156_RS11615	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FE156_RS11655	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FE156_RS11660	COG1609	Transcriptional regulator
FE156_RS11675	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FE156_RS11690	COG0477	Major facilitator Superfamily
FE156_RS11705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FE156_RS11745	COG1309	transcriptional regulator
FE156_RS11770	COG2271	Major facilitator Superfamily
FE156_RS11790	COG1366	Belongs to the anti-sigma-factor antagonist family
FE156_RS11875	COG4821	SIS domain
FE156_RS11885	COG0259	pyridoxamine-phosphate oxidase activity
FE156_RS11905	COG1024	Enoyl-CoA hydratase
FE156_RS11970	COG0583	DNA-binding transcription factor activity
FE156_RS11980	COG2205	protein histidine kinase activity
FE156_RS12000	COG2124	cytochrome p450
FE156_RS12005	COG2124	cytochrome p450
FE156_RS12010	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FE156_RS12110	COG0667	Aldo Keto reductase
FE156_RS12170	COG2814	Major facilitator Superfamily
FE156_RS12180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FE156_RS12185	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FE156_RS12190	COG1278	Cold shock
FE156_RS12200	COG2197	response regulator
FE156_RS12230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FE156_RS12235	COG1120	ATPase activity
FE156_RS12240	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE156_RS12245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE156_RS12275	COG2124	cytochrome p450
FE156_RS12330	COG1061	Type III restriction enzyme res subunit
FE156_RS12490	COG0406	alpha-ribazole phosphatase activity
FE156_RS12500	COG1737	Transcriptional regulator
FE156_RS12505	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FE156_RS12510	COG1263	PTS System
FE156_RS12510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FE156_RS12550	COG1278	Cold shock
FE156_RS12680	COG1105	Belongs to the carbohydrate kinase PfkB family
FE156_RS12705	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FE156_RS12720	COG1063	alcohol dehydrogenase
FE156_RS12735	COG1309	transcriptional regulator
FE156_RS12750	COG1136	(ABC) transporter
FE156_RS12785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE156_RS12915	COG1136	(ABC) transporter
FE156_RS12915	COG0577	efflux transmembrane transporter activity
FE156_RS12920	COG0577	efflux transmembrane transporter activity
FE156_RS12970	COG0604	alcohol dehydrogenase
FE156_RS12975	COG4585	Histidine kinase
FE156_RS12980	COG2197	response regulator
FE156_RS12990	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FE156_RS13010	COG0301	tRNA thio-modification
FE156_RS13030	COG0513	Belongs to the DEAD box helicase family
FE156_RS13035	COG1278	Cold shock
FE156_RS13065	COG2770	Histidine kinase
FE156_RS13065	COG2208	phosphoserine phosphatase activity
FE156_RS13110	COG3842	ATPase activity
FE156_RS13120	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FE156_RS13130	COG1253	flavin adenine dinucleotide binding
FE156_RS13180	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FE156_RS13185	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FE156_RS13190	COG1329	Transcriptional regulator
FE156_RS13205	COG0745	RESPONSE REGULATOR receiver
FE156_RS13210	COG5002	protein histidine kinase activity
FE156_RS13215	COG0704	Plays a role in the regulation of phosphate uptake
FE156_RS13225	COG2076	Multidrug Resistance protein
FE156_RS13250	COG3311	Transcriptional regulator
FE156_RS13260	COG0588	phosphoglycerate mutase activity
FE156_RS13285	COG0438	transferase activity, transferring glycosyl groups
FE156_RS13320	COG1309	transcriptional regulator
FE156_RS13340	COG2226	methyltransferase
FE156_RS13350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE156_RS13435	COG0789	Transcriptional regulator
FE156_RS13450	COG1490	D-aminoacyl-tRNA deacylase activity
FE156_RS13455	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FE156_RS13460	COG0735	belongs to the Fur family
FE156_RS13465	COG3485	protocatechuate 3,4-dioxygenase
FE156_RS13505	COG2897	thiosulfate sulfurtransferase activity
FE156_RS13530	COG0745	RESPONSE REGULATOR receiver
FE156_RS13535	COG1609	Transcriptional regulator
FE156_RS13540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE156_RS13545	COG0745	RESPONSE REGULATOR receiver
FE156_RS13560	COG4214	carbohydrate transport
FE156_RS13565	COG1129	ABC transporter
FE156_RS13580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FE156_RS13615	COG2160	L-arabinose isomerase activity
FE156_RS13620	COG0235	Class ii aldolase
FE156_RS13630	COG0456	acetyltransferase
FE156_RS13655	COG4941	Belongs to the sigma-70 factor family
FE156_RS13660	COG1725	Transcriptional regulator
FE156_RS13670	COG1131	(ABC) transporter
FE156_RS13685	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FE156_RS13710	COG2267	carboxylic ester hydrolase activity
FE156_RS13725	COG3415	Transposase
FE156_RS13725	COG2801	Transposase and inactivated derivatives
FE156_RS13775	COG1595	DNA-templated transcription, initiation
FE156_RS13820	COG3903	Transcriptional regulator
FE156_RS13820	COG3629	intracellular signal transduction
FE156_RS13835	COG2770	Histidine kinase
FE156_RS13835	COG2208	phosphoserine phosphatase activity
FE156_RS13885	COG2318	DinB family
FE156_RS13890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FE156_RS13900	COG0494	nUDIX hydrolase
FE156_RS13900	COG0406	alpha-ribazole phosphatase activity
FE156_RS13920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FE156_RS13925	COG0306	phosphate transporter
FE156_RS13935	COG1937	Protein conserved in bacteria
FE156_RS13945	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS13960	COG0671	phosphoesterase, PA-phosphatase related
FE156_RS13965	COG0739	heme binding
FE156_RS13965	COG1196	nuclear chromosome segregation
FE156_RS13965	COG0741	lytic transglycosylase activity
FE156_RS13995	COG0509	glycine decarboxylation via glycine cleavage system
FE156_RS14045	COG2175	clavaminate synthase activity
FE156_RS14050	COG3251	PFAM MbtH domain protein
FE156_RS14055	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FE156_RS14075	COG0577	efflux transmembrane transporter activity
FE156_RS14075	COG1136	(ABC) transporter
FE156_RS14135	COG2124	cytochrome p450
FE156_RS14140	COG2267	carboxylic ester hydrolase activity
FE156_RS14175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FE156_RS14205	COG4585	Histidine kinase
FE156_RS14210	COG0702	epimerase
FE156_RS14220	COG3844	kynureninase activity
FE156_RS14245	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FE156_RS14250	COG0191	fructose-bisphosphate aldolase activity
FE156_RS14255	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FE156_RS14270	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FE156_RS14300	COG2378	regulation of single-species biofilm formation
FE156_RS14315	COG0477	Major facilitator Superfamily
FE156_RS14345	COG0789	Transcriptional regulator
FE156_RS14355	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FE156_RS14360	COG0443	Heat shock 70 kDa protein
FE156_RS14400	COG1131	(ABC) transporter
FE156_RS14420	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FE156_RS14425	COG1120	ATPase activity
FE156_RS14430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE156_RS14435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE156_RS14475	COG1695	Transcriptional regulator
FE156_RS14500	COG0717	Belongs to the dCTP deaminase family
FE156_RS14530	COG0247	lactate metabolic process
FE156_RS14530	COG2181	nitrate reductase activity
FE156_RS14535	COG0657	acetylesterase activity
FE156_RS14560	COG0477	Major facilitator Superfamily
FE156_RS14570	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE156_RS14610	COG1937	Protein conserved in bacteria
FE156_RS14615	COG2268	Band 7 protein
FE156_RS14630	COG1316	TRANSCRIPTIONal
FE156_RS14670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FE156_RS14680	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FE156_RS14695	COG1741	Belongs to the pirin family
FE156_RS14705	COG1960	acyl-CoA dehydrogenase activity
FE156_RS14725	COG1362	aminopeptidase activity
FE156_RS14775	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE156_RS14780	COG0022	dehydrogenase e1 component
FE156_RS14795	COG0515	serine threonine protein kinase
FE156_RS14800	COG0515	serine threonine protein kinase
FE156_RS14825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FE156_RS14830	COG0303	'Molybdopterin
FE156_RS14855	COG1522	sequence-specific DNA binding
FE156_RS14900	COG1733	regulation of RNA biosynthetic process
FE156_RS14905	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FE156_RS14915	COG1716	ATPase activity
FE156_RS14920	COG1716	ATPase activity
FE156_RS14945	COG0515	serine threonine protein kinase
FE156_RS14950	COG3764	Sortase (surface protein transpeptidase)
FE156_RS14955	COG3764	Sortase (surface protein transpeptidase)
FE156_RS14980	COG0705	Rhomboid family
FE156_RS15000	COG1309	transcriptional regulator
FE156_RS15005	COG1278	Cold shock
FE156_RS15075	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FE156_RS15080	COG0187	DNA topoisomerase II activity
FE156_RS15085	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FE156_RS15090	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FE156_RS15095	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FE156_RS15100	COG0592	DNA-directed DNA polymerase activity
FE156_RS15110	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FE156_RS15115	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FE156_RS15120	COG0594	ribonuclease P activity
FE156_RS15125	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FE156_RS15130	COG0706	membrane insertase activity
FE156_RS15140	COG0357	Ribosomal RNA small subunit methyltransferase G
FE156_RS15145	COG1192	Involved in chromosome partitioning
FE156_RS15160	COG3118	belongs to the thioredoxin family
FE156_RS15165	COG0492	ferredoxin-NADP+ reductase activity
FE156_RS15175	COG1595	DNA-templated transcription, initiation
FE156_RS15180	COG0515	serine threonine protein kinase
FE156_RS15180	COG2815	serine threonine protein kinase
FE156_RS15195	COG0617	tRNA 3'-terminal CCA addition
FE156_RS15225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FE156_RS15250	COG0360	Binds together with S18 to 16S ribosomal RNA
FE156_RS15255	COG0629	single-stranded DNA binding
FE156_RS15260	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FE156_RS15265	COG0359	binds to the 23S rRNA
FE156_RS15275	COG0305	Participates in initiation and elongation during chromosome replication
FE156_RS15280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FE156_RS15285	COG0110	maltose O-acetyltransferase activity
FE156_RS15330	COG0626	cystathionine gamma-synthase activity
FE156_RS15335	COG1950	PFAM Membrane protein of
FE156_RS15340	COG0662	Cupin 2, conserved barrel domain protein
FE156_RS15365	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FE156_RS15380	COG1609	Transcriptional regulator
FE156_RS15385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FE156_RS15390	COG1271	oxidase subunit
FE156_RS15395	COG1294	oxidase, subunit
FE156_RS15400	COG4988	ABC transporter
FE156_RS15410	COG0741	lytic transglycosylase activity
FE156_RS15410	COG1196	nuclear chromosome segregation
FE156_RS15410	COG0739	heme binding
FE156_RS15415	COG0561	phosphatase activity
FE156_RS15420	COG3547	Transposase (IS116 IS110 IS902 family)
FE156_RS15440	COG1131	(ABC) transporter
FE156_RS15460	COG0561	phosphatase activity
FE156_RS15465	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FE156_RS15470	COG0077	Prephenate dehydratase
FE156_RS15475	COG2837	iron assimilation
FE156_RS15490	COG1999	signal sequence binding
FE156_RS15510	COG0006	proline dipeptidase activity
FE156_RS15525	COG0653	protein targeting
FE156_RS15545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE156_RS15565	COG1595	DNA-templated transcription, initiation
FE156_RS15570	COG0318	PFAM AMP-dependent synthetase and ligase
FE156_RS15620	COG0477	Major facilitator Superfamily
FE156_RS15640	COG0477	Major facilitator Superfamily
FE156_RS15660	COG1191	sigma factor activity
FE156_RS15690	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FE156_RS15760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FE156_RS15800	COG0151	Belongs to the GarS family
FE156_RS15815	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FE156_RS15825	COG2197	response regulator
FE156_RS15860	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FE156_RS15865	COG0047	phosphoribosylformylglycinamidine synthase activity
FE156_RS15870	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FE156_RS15885	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FE156_RS15920	COG1643	Atp-dependent helicase
FE156_RS15965	COG0513	Belongs to the DEAD box helicase family
FE156_RS15995	COG0542	response to heat
FE156_RS16005	COG2261	transglycosylase associated protein
FE156_RS16025	COG0667	Aldo Keto reductase
FE156_RS16040	COG0579	oxidoreductase
FE156_RS16055	COG1470	cell adhesion involved in biofilm formation
FE156_RS16055	COG0366	Alpha amylase catalytic
FE156_RS16130	COG0596	Alpha beta hydrolase
FE156_RS16150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FE156_RS16205	COG2197	response regulator
FE156_RS16220	COG0666	response to abiotic stimulus
FE156_RS16295	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FE156_RS16300	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FE156_RS16310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FE156_RS16355	COG0596	Alpha beta hydrolase
FE156_RS16380	COG2318	DinB family
FE156_RS16395	COG1136	(ABC) transporter
FE156_RS16395	COG0577	efflux transmembrane transporter activity
FE156_RS16475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FE156_RS16560	COG1609	Transcriptional regulator
FE156_RS16605	COG0003	Pfam Anion-transporting ATPase
FE156_RS16615	COG0251	oxidation-reduction process
FE156_RS16625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE156_RS16655	COG2267	carboxylic ester hydrolase activity
FE156_RS16665	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FE156_RS16670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FE156_RS16675	COG0659	secondary active sulfate transmembrane transporter activity
FE156_RS16735	COG1205	dead DEAH box helicase
FE156_RS16735	COG1111	helicase
FE156_RS16740	COG1366	Belongs to the anti-sigma-factor antagonist family
FE156_RS16755	COG2890	protein-(glutamine-N5) methyltransferase activity
FE156_RS16765	COG3547	Transposase (IS116 IS110 IS902 family)
FE156_RS16770	COG1754	DNA topoisomerase type I activity
FE156_RS16770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FE156_RS16775	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FE156_RS16800	COG0789	Transcriptional regulator
FE156_RS16815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FE156_RS16820	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FE156_RS16835	COG0789	Transcriptional regulator
FE156_RS16845	COG0825	malonyl-CoA metabolic process
FE156_RS16845	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FE156_RS16850	COG0318	PFAM AMP-dependent synthetase and ligase
FE156_RS16860	COG2186	Transcriptional regulator
FE156_RS16875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FE156_RS16885	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FE156_RS16940	COG0494	nUDIX hydrolase
FE156_RS16945	COG1252	NADH dehydrogenase
FE156_RS16960	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS16965	COG0640	Transcriptional regulator
FE156_RS16975	COG1316	TRANSCRIPTIONal
FE156_RS16980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FE156_RS16995	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FE156_RS17000	COG1309	transcriptional regulator
FE156_RS17010	COG5001	Diguanylate cyclase
FE156_RS17040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE156_RS17045	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FE156_RS17050	COG0783	Belongs to the Dps family
FE156_RS17085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FE156_RS17090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FE156_RS17110	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FE156_RS17145	COG0456	acetyltransferase
FE156_RS17145	COG1214	PFAM Peptidase M22, glycoprotease
FE156_RS17180	COG0739	heme binding
FE156_RS17190	COG2814	Major facilitator Superfamily
FE156_RS17190	COG0477	Major facilitator Superfamily
FE156_RS17205	COG2159	amidohydrolase
FE156_RS17215	COG2186	Transcriptional regulator
FE156_RS17245	COG0501	Belongs to the peptidase M48B family
FE156_RS17255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FE156_RS17255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FE156_RS17290	COG1289	transmembrane transporter activity
FE156_RS17315	COG1012	belongs to the aldehyde dehydrogenase family
FE156_RS17320	COG2318	DinB family
FE156_RS17330	COG0655	NAD(P)H dehydrogenase (quinone) activity
FE156_RS17335	COG0789	Transcriptional regulator
FE156_RS17340	COG0586	Pfam SNARE associated Golgi protein
FE156_RS17350	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FE156_RS17355	COG2027	D-alanyl-D-alanine carboxypeptidase
FE156_RS17365	COG0037	tRNA processing
FE156_RS17380	COG0302	gtp cyclohydrolase
FE156_RS17395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FE156_RS17415	COG1174	glycine betaine transport
FE156_RS17420	COG1174	glycine betaine transport
FE156_RS17425	COG1732	Glycine betaine
FE156_RS17435	COG0477	Major facilitator Superfamily
FE156_RS17510	COG1012	belongs to the aldehyde dehydrogenase family
FE156_RS17525	COG4585	Histidine kinase
FE156_RS17530	COG2197	response regulator
FE156_RS17550	COG0649	NAD binding
FE156_RS17580	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FE156_RS17585	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FE156_RS17595	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FE156_RS17615	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FE156_RS17645	COG0739	heme binding
FE156_RS17650	COG2205	protein histidine kinase activity
FE156_RS17655	COG0745	RESPONSE REGULATOR receiver
FE156_RS17665	COG1595	DNA-templated transcription, initiation
FE156_RS17675	COG0671	phosphoesterase, PA-phosphatase related
FE156_RS17685	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FE156_RS17720	COG0248	Ppx GppA phosphatase
FE156_RS17730	COG1082	Xylose isomerase domain protein TIM barrel
FE156_RS17735	COG1309	transcriptional regulator
FE156_RS17740	COG0129	dihydroxy-acid dehydratase activity
FE156_RS17750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FE156_RS17770	COG0842	Transport permease protein
FE156_RS17770	COG1129	ABC transporter
FE156_RS17780	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FE156_RS17785	COG0180	Tryptophanyl-tRNA synthetase
FE156_RS17810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FE156_RS17820	COG0123	including yeast histone deacetylase and acetoin utilization protein
FE156_RS17875	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FE156_RS17880	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FE156_RS17885	COG0181	hydroxymethylbilane synthase activity
FE156_RS17890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FE156_RS17890	COG1648	precorrin-2 dehydrogenase activity
FE156_RS17895	COG0113	porphobilinogen synthase activity
FE156_RS17925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE156_RS17930	COG0018	arginyl-trna synthetase
FE156_RS17935	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FE156_RS17960	COG1690	Belongs to the RtcB family
FE156_RS17965	COG0659	secondary active sulfate transmembrane transporter activity
FE156_RS18015	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FE156_RS18020	COG0406	alpha-ribazole phosphatase activity
FE156_RS18050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FE156_RS18055	COG0785	Cytochrome C biogenesis protein
FE156_RS18065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE156_RS18080	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FE156_RS18085	COG0109	protoheme IX farnesyltransferase activity
FE156_RS18090	COG0163	prenyltransferase activity
FE156_RS18100	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FE156_RS18115	COG1301	dicarboxylic acid transport
FE156_RS18190	COG0183	Belongs to the thiolase family
FE156_RS18200	COG1278	Cold shock
FE156_RS18205	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FE156_RS18210	COG1674	ftsk spoiiie
FE156_RS18385	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FE156_RS18395	COG2226	methyltransferase
FE156_RS18425	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE156_RS18430	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE156_RS18435	COG0649	NAD binding
FE156_RS18445	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FE156_RS18450	COG1034	ATP synthesis coupled electron transport
FE156_RS18455	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FE156_RS18460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE156_RS18470	COG0713	ATP synthesis coupled electron transport
FE156_RS18475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FE156_RS18485	COG1007	ATP synthesis coupled electron transport
FE156_RS18505	COG0561	phosphatase activity
FE156_RS18515	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FE156_RS18525	COG3104	oligopeptide transport
FE156_RS18550	COG0488	(ABC) transporter
FE156_RS18560	COG0702	epimerase
FE156_RS18570	COG1013	pyruvate-flavodoxin oxidoreductase activity
FE156_RS18575	COG0674	pyruvate-flavodoxin oxidoreductase activity
FE156_RS18575	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FE156_RS18585	COG4585	Histidine kinase
FE156_RS18590	COG4585	Histidine kinase
FE156_RS18595	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE156_RS18600	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE156_RS18605	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE156_RS18610	COG0839	Belongs to the complex I subunit 6 family
FE156_RS18615	COG0713	ATP synthesis coupled electron transport
FE156_RS18620	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FE156_RS18630	COG1007	ATP synthesis coupled electron transport
FE156_RS18640	COG3304	Inner membrane component domain
FE156_RS18645	COG2261	transglycosylase associated protein
FE156_RS18650	COG1666	GTP binding
FE156_RS18660	COG0702	epimerase
FE156_RS18665	COG0402	S-adenosylhomocysteine deaminase activity
FE156_RS18680	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FE156_RS18685	COG2030	dehydratase
FE156_RS18695	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FE156_RS18705	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FE156_RS18710	COG0436	Aminotransferase
FE156_RS18735	COG0081	regulation of translation
FE156_RS18745	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FE156_RS18750	COG0222	ribosome binding
FE156_RS18760	COG0085	RNA polymerase activity
FE156_RS18765	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FE156_RS18805	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FE156_RS18810	COG0049	tRNA binding
FE156_RS18815	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FE156_RS18860	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FE156_RS18870	COG0051	transcription antitermination factor activity, RNA binding
FE156_RS18875	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FE156_RS18880	COG0088	Forms part of the polypeptide exit tunnel
FE156_RS18885	COG0089	rRNA binding
FE156_RS18890	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FE156_RS18895	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FE156_RS18900	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FE156_RS18905	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FE156_RS18910	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FE156_RS18915	COG0255	Belongs to the universal ribosomal protein uL29 family
FE156_RS18920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FE156_RS18925	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FE156_RS18930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FE156_RS18935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FE156_RS18940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FE156_RS18950	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FE156_RS18955	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FE156_RS18960	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FE156_RS18965	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FE156_RS18970	COG1841	ribosomal large subunit assembly
FE156_RS18975	COG0200	Binds to the 23S rRNA
FE156_RS18980	COG0201	protein transport
FE156_RS18985	COG0563	adenylate kinase activity
FE156_RS18995	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FE156_RS19000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FE156_RS19005	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FE156_RS19010	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FE156_RS19020	COG0203	ribosomal protein L17
FE156_RS19025	COG0101	tRNA pseudouridine synthase activity
FE156_RS19035	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FE156_RS19040	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FE156_RS19045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FE156_RS19050	COG1072	(Pantothenic acid kinase))
FE156_RS19065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FE156_RS19075	COG4977	sequence-specific DNA binding
FE156_RS19085	COG0736	holo-[acyl-carrier-protein] synthase activity
FE156_RS19150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FE156_RS19160	COG0802	atpase or kinase
FE156_RS19180	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FE156_RS19215	COG0726	polysaccharide deacetylase
FE156_RS19235	COG4221	oxidoreductase activity
FE156_RS19240	COG0583	DNA-binding transcription factor activity
FE156_RS19250	COG2197	response regulator
FE156_RS19255	COG1595	DNA-templated transcription, initiation
FE156_RS19265	COG0516	GMP reductase activity
FE156_RS19275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FE156_RS19310	COG1012	belongs to the aldehyde dehydrogenase family
FE156_RS19330	COG0519	Catalyzes the synthesis of GMP from XMP
FE156_RS19330	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FE156_RS19340	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS19380	COG2197	response regulator
FE156_RS19385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FE156_RS19435	COG1846	Transcriptional regulator
FE156_RS19435	COG0456	acetyltransferase
FE156_RS19505	COG0741	lytic transglycosylase activity
FE156_RS19505	COG1196	nuclear chromosome segregation
FE156_RS19505	COG0739	heme binding
FE156_RS19510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FE156_RS19515	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FE156_RS19515	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FE156_RS19530	COG0714	Associated with various cellular activities
FE156_RS19535	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FE156_RS19540	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FE156_RS19545	COG0045	succinate-CoA ligase (ADP-forming) activity
FE156_RS19575	COG0138	bifunctional purine biosynthesis protein purh
FE156_RS19585	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FE156_RS19620	COG0039	L-malate dehydrogenase activity
FE156_RS19640	COG1012	belongs to the aldehyde dehydrogenase family
FE156_RS19650	COG0517	IMP dehydrogenase activity
FE156_RS19650	COG4175	Glycine betaine
FE156_RS19655	COG4176	ABC-type proline glycine betaine transport system permease component
FE156_RS19680	COG0395	ABC-type sugar transport system, permease component
FE156_RS19685	COG1175	transmembrane transport
FE156_RS19705	COG2362	D-Aminopeptidase
FE156_RS19710	COG1609	Transcriptional regulator
FE156_RS19720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FE156_RS19730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE156_RS19740	COG0754	glutathionylspermidine amidase activity
FE156_RS19750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FE156_RS19785	COG0180	Tryptophanyl-tRNA synthetase
FE156_RS19825	COG1295	ribonuclease BN
FE156_RS19830	COG1686	Belongs to the peptidase S11 family
FE156_RS19840	COG1408	metallophosphoesterase
FE156_RS19885	COG1309	transcriptional regulator
FE156_RS19900	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FE156_RS19905	COG1053	succinate dehydrogenase
FE156_RS19915	COG2009	succinate dehydrogenase
FE156_RS19955	COG1215	transferase activity, transferring glycosyl groups
FE156_RS19960	COG1595	DNA-templated transcription, initiation
FE156_RS19990	COG1216	Glycosyl transferase, family 2
FE156_RS20000	COG1083	cytidylyl-transferase
FE156_RS20005	COG2089	acid synthase
FE156_RS20015	COG1473	amidohydrolase
FE156_RS20015	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FE156_RS20020	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FE156_RS20035	COG2197	response regulator
FE156_RS20050	COG1744	ABC transporter substrate-binding protein PnrA-like
FE156_RS20055	COG3845	ABC transporter
FE156_RS20060	COG4603	Belongs to the binding-protein-dependent transport system permease family
FE156_RS20065	COG1079	Belongs to the binding-protein-dependent transport system permease family
FE156_RS20095	COG2814	Major facilitator Superfamily
FE156_RS20110	COG1136	(ABC) transporter
FE156_RS20130	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FE156_RS20155	COG2205	protein histidine kinase activity
FE156_RS20160	COG0745	RESPONSE REGULATOR receiver
FE156_RS20165	COG1595	DNA-templated transcription, initiation
FE156_RS20210	COG1012	belongs to the aldehyde dehydrogenase family
FE156_RS20225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FE156_RS20260	COG4770	biotin carboxylase activity
FE156_RS20270	COG0424	maF-like protein
FE156_RS20280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FE156_RS20290	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FE156_RS20295	COG1024	Enoyl-CoA hydratase
FE156_RS20305	COG2986	histidine ammonia-lyase
FE156_RS20325	COG1136	(ABC) transporter
FE156_RS20330	COG1064	alcohol dehydrogenase
FE156_RS20335	COG2318	DinB family
FE156_RS20360	COG2255	four-way junction helicase activity
FE156_RS20365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FE156_RS20380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FE156_RS20390	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FE156_RS20425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FE156_RS20460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FE156_RS20490	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FE156_RS20520	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FE156_RS20535	COG1414	Transcriptional regulator
FE156_RS20540	COG0251	oxidation-reduction process
FE156_RS20610	COG2197	response regulator
FE156_RS20655	COG0656	L-ascorbic acid biosynthetic process
FE156_RS20660	COG2304	oxidoreductase activity
FE156_RS20685	COG0667	Aldo Keto reductase
FE156_RS20690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FE156_RS20695	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FE156_RS20715	COG0450	alkyl hydroperoxide reductase
FE156_RS20720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FE156_RS20730	COG1136	(ABC) transporter
FE156_RS20750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FE156_RS20765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FE156_RS20775	COG0114	fumarate hydratase activity
FE156_RS20785	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FE156_RS20785	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FE156_RS20830	COG0778	Nitroreductase
FE156_RS20835	COG1722	exodeoxyribonuclease VII activity
FE156_RS20840	COG1570	exodeoxyribonuclease VII activity
FE156_RS20850	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FE156_RS20865	COG0012	GTP binding
FE156_RS20905	COG0406	alpha-ribazole phosphatase activity
FE156_RS20930	COG0745	RESPONSE REGULATOR receiver
FE156_RS20990	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FE156_RS20995	COG4977	sequence-specific DNA binding
FE156_RS21010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FE156_RS21035	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FE156_RS21055	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS21115	COG1960	acyl-CoA dehydrogenase activity
FE156_RS21130	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FE156_RS21135	COG1309	transcriptional regulator
FE156_RS21145	COG1946	Acyl-CoA thioesterase
FE156_RS21180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE156_RS21190	COG3960	tartronate-semialdehyde synthase activity
FE156_RS21255	COG3718	enzyme involved in inositol metabolism
FE156_RS21260	COG3962	Belongs to the TPP enzyme family
FE156_RS21295	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FE156_RS21300	COG0454	-acetyltransferase
FE156_RS21300	COG0456	acetyltransferase
FE156_RS21305	COG1131	(ABC) transporter
FE156_RS21335	COG3903	Transcriptional regulator
FE156_RS21335	COG3629	intracellular signal transduction
FE156_RS21375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FE156_RS21445	COG1136	(ABC) transporter
FE156_RS21465	COG0667	Aldo Keto reductase
FE156_RS21470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FE156_RS21500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE156_RS21520	COG1486	melibiose metabolic process
FE156_RS21530	COG0668	transmembrane transport
FE156_RS21545	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE156_RS21565	COG0583	DNA-binding transcription factor activity
FE156_RS21620	COG4266	Belongs to the allantoicase family
FE156_RS21655	COG0076	glutamate decarboxylase activity
FE156_RS21660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FE156_RS21665	COG1113	amino acid transport
FE156_RS21670	COG1113	amino acid transport
FE156_RS21675	COG1268	BioY protein
FE156_RS21680	COG1113	amino acid transport
FE156_RS21710	COG3594	Acyltransferase
FE156_RS21730	COG0544	peptidyl-prolyl cis-trans isomerase activity
FE156_RS21735	COG0740	serine-type endopeptidase activity
FE156_RS21740	COG0740	serine-type endopeptidase activity
FE156_RS21745	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FE156_RS21755	COG0525	valine-tRNA ligase activity
FE156_RS21760	COG0285	dihydrofolate synthase activity
FE156_RS21770	COG0105	UTP biosynthetic process
FE156_RS21795	COG0772	Belongs to the SEDS family
FE156_RS21825	COG1530	ribonuclease E activity
FE156_RS21830	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FE156_RS21835	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FE156_RS21840	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FE156_RS21860	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FE156_RS21870	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FE156_RS21890	COG0501	Belongs to the peptidase M48B family
FE156_RS21895	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FE156_RS21905	COG0799	negative regulation of ribosome biogenesis
FE156_RS21910	COG0588	phosphoglycerate mutase activity
FE156_RS21935	COG0495	leucyl-tRNA aminoacylation
FE156_RS21945	COG1307	EDD domain protein, DegV family
FE156_RS21950	COG1555	photosystem II stabilization
FE156_RS21980	COG0268	Binds directly to 16S ribosomal RNA
FE156_RS21985	COG0481	GTPase activity
FE156_RS22015	COG0484	heat shock protein binding
FE156_RS22040	COG0537	adenosine 5'-monophosphoramidase activity
FE156_RS22045	COG1234	tRNA 3'-trailer cleavage
FE156_RS22065	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FE156_RS22070	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FE156_RS22095	COG1486	melibiose metabolic process
FE156_RS22100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE156_RS22120	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FE156_RS22130	COG2315	Protein conserved in bacteria
FE156_RS22140	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FE156_RS22155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FE156_RS22165	COG1381	Involved in DNA repair and RecF pathway recombination
FE156_RS22170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FE156_RS22180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FE156_RS22185	COG1121	(ABC) transporter
FE156_RS22195	COG0423	glycine-tRNA ligase activity
FE156_RS22260	COG3467	pyridoxamine 5'-phosphate
FE156_RS22270	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FE156_RS22275	COG1940	carbohydrate kinase activity
FE156_RS22275	COG1846	Transcriptional regulator
FE156_RS22290	COG0574	Belongs to the PEP-utilizing enzyme family
FE156_RS22290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FE156_RS22315	COG0829	nickel cation binding
FE156_RS22320	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FE156_RS22325	COG0830	nickel cation binding
FE156_RS22330	COG0804	urea catabolic process
FE156_RS22335	COG0832	Belongs to the urease beta subunit family
FE156_RS22345	COG0738	Major facilitator superfamily
FE156_RS22360	COG2226	methyltransferase
FE156_RS22365	COG0736	holo-[acyl-carrier-protein] synthase activity
FE156_RS22370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FE156_RS22380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FE156_RS22390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FE156_RS22395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FE156_RS22405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FE156_RS22455	COG1070	Carbohydrate kinase
FE156_RS22475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FE156_RS22480	COG0358	DNA primase activity
FE156_RS22490	COG3290	protein histidine kinase activity
FE156_RS22495	COG4565	transcriptional regulatory protein
FE156_RS22500	COG2851	Citrate transporter
FE156_RS22520	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FE156_RS22540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE156_RS22570	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS22585	COG2890	protein-(glutamine-N5) methyltransferase activity
FE156_RS22600	COG1077	Cell shape determining protein MreB Mrl
FE156_RS22625	COG2130	NADP-dependent
FE156_RS22630	COG1764	response to oxidative stress
FE156_RS22675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FE156_RS22680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FE156_RS22695	COG1741	Belongs to the pirin family
FE156_RS22710	COG0789	Transcriptional regulator
FE156_RS22715	COG0667	Aldo Keto reductase
FE156_RS22730	COG2197	response regulator
FE156_RS22735	COG4585	Histidine kinase
FE156_RS22755	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FE156_RS22805	COG1358	cellular component organization or biogenesis
FE156_RS22820	COG0586	Pfam SNARE associated Golgi protein
FE156_RS22945	COG0438	transferase activity, transferring glycosyl groups
FE156_RS22980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FE156_RS22985	COG1960	acyl-CoA dehydrogenase activity
FE156_RS23020	COG0800	Aldolase
FE156_RS23025	COG3022	response to hydroperoxide
FE156_RS23055	COG1733	regulation of RNA biosynthetic process
FE156_RS23100	COG0076	glutamate decarboxylase activity
FE156_RS23115	COG2814	Major facilitator Superfamily
FE156_RS23120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FE156_RS23130	COG1834	amidinotransferase
FE156_RS23150	COG1120	ATPase activity
FE156_RS23155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE156_RS23160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FE156_RS23175	COG0384	phenazine biosynthesis protein PhzF
FE156_RS23205	COG1994	Peptidase M50
FE156_RS23210	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FE156_RS23225	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FE156_RS23225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE156_RS23230	COG2132	Multicopper oxidase
FE156_RS23250	COG0174	glutamine synthetase
FE156_RS23310	COG1228	amidohydrolase
FE156_RS23325	COG1609	Transcriptional regulator
FE156_RS23330	COG2182	Extracellular solute-binding protein
FE156_RS23335	COG1175	transmembrane transport
FE156_RS23340	COG0395	ABC-type sugar transport system, permease component
FE156_RS23345	COG0366	Alpha amylase catalytic
FE156_RS23370	COG1309	transcriptional regulator
FE156_RS23390	COG3293	Transposase
FE156_RS23410	COG0745	RESPONSE REGULATOR receiver
FE156_RS23445	COG1012	belongs to the aldehyde dehydrogenase family
FE156_RS23470	COG3547	Transposase (IS116 IS110 IS902 family)
FE156_RS23515	COG2326	polyphosphate kinase activity
FE156_RS23530	COG2376	Dihydroxyacetone kinase
FE156_RS23535	COG2376	Dihydroxyacetone kinase
FE156_RS23540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FE156_RS23580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FE156_RS23585	COG0321	lipoyl(octanoyl) transferase activity
FE156_RS23635	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FE156_RS23645	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE156_RS23650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE156_RS23655	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FE156_RS23670	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FE156_RS23715	COG2197	response regulator
FE156_RS23720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE156_RS23725	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FE156_RS23750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE156_RS23755	COG1104	cysteine desulfurase activity
FE156_RS23760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FE156_RS23765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FE156_RS23775	COG1376	ErfK ybiS ycfS ynhG family protein
FE156_RS23785	COG1845	cytochrome c oxidase, subunit III
FE156_RS23790	COG2010	Cytochrome c
FE156_RS23795	COG0723	plastoquinol--plastocyanin reductase activity
FE156_RS23800	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FE156_RS23805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FE156_RS23810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FE156_RS23815	COG1929	Belongs to the glycerate kinase type-1 family
FE156_RS23825	COG0745	RESPONSE REGULATOR receiver
FE156_RS23830	COG5002	protein histidine kinase activity
FE156_RS23880	COG0438	transferase activity, transferring glycosyl groups
FE156_RS23900	COG0003	Pfam Anion-transporting ATPase
FE156_RS23910	COG1940	carbohydrate kinase activity
FE156_RS23935	COG4585	Histidine kinase
FE156_RS23940	COG2197	response regulator
FE156_RS23945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FE156_RS23960	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FE156_RS23965	COG0243	molybdopterin cofactor binding
FE156_RS23970	COG2193	ferroxidase activity
FE156_RS23975	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FE156_RS23980	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FE156_RS23995	COG2815	serine threonine protein kinase
FE156_RS23995	COG0515	serine threonine protein kinase
FE156_RS24000	COG2022	thiamine diphosphate biosynthetic process
FE156_RS24010	COG2022	thiamine diphosphate biosynthetic process
FE156_RS24010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE156_RS24025	COG0352	thiamine-phosphate diphosphorylase activity
FE156_RS24040	COG1233	COG1233 Phytoene dehydrogenase and related
FE156_RS24045	COG1309	transcriptional regulator
FE156_RS24055	COG1129	ABC transporter
FE156_RS24060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FE156_RS24080	COG0714	Associated with various cellular activities
FE156_RS24090	COG0275	rRNA processing
FE156_RS24105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FE156_RS24115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FE156_RS24120	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FE156_RS24130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FE156_RS24135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FE156_RS24140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FE156_RS24145	COG1496	oxidoreductase activity
FE156_RS24155	COG1799	cell septum assembly
FE156_RS24165	COG3599	regulation of cell shape
FE156_RS24170	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FE156_RS24180	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FE156_RS24190	COG2153	protein acetylation
FE156_RS24230	COG1432	Conserved Protein
FE156_RS24250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FE156_RS24270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FE156_RS24275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FE156_RS24280	COG0131	Imidazoleglycerol-phosphate dehydratase
FE156_RS24285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FE156_RS24290	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FE156_RS24295	COG0251	oxidation-reduction process
FE156_RS24300	COG0107	imidazoleglycerol-phosphate synthase activity
FE156_RS24305	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FE156_RS24315	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FE156_RS24325	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FE156_RS24345	COG0134	indole-3-glycerol-phosphate synthase activity
FE156_RS24350	COG0133	tryptophan synthase activity
FE156_RS24355	COG0159	tryptophan synthase activity
FE156_RS24365	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FE156_RS24375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FE156_RS24400	COG1397	ADP-ribosylglycohydrolase
FE156_RS24410	COG0069	glutamate synthase activity
FE156_RS24410	COG0067	glutamate synthase
FE156_RS24410	COG0070	glutamate synthase
FE156_RS24425	COG1278	Cold shock
FE156_RS24430	COG0513	Belongs to the DEAD box helicase family
FE156_RS24440	COG1605	Chorismate mutase
FE156_RS24440	COG0287	Prephenate dehydrogenase
FE156_RS24475	COG0737	Belongs to the 5'-nucleotidase family
FE156_RS24515	COG0559	Belongs to the binding-protein-dependent transport system permease family
FE156_RS24530	COG2050	protein possibly involved in aromatic compounds catabolism
FE156_RS24550	COG1643	Atp-dependent helicase
FE156_RS24555	COG2226	methyltransferase
FE156_RS24575	COG0237	dephospho-CoA kinase activity
FE156_RS24595	COG1288	antiporter activity
FE156_RS24645	COG0477	Major facilitator Superfamily
FE156_RS24650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FE156_RS24655	COG0584	glycerophosphoryl diester phosphodiesterase
FE156_RS24665	COG0556	nucleotide-excision repair
FE156_RS24685	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FE156_RS24690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE156_RS24700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FE156_RS24715	COG0322	excinuclease ABC activity
FE156_RS24720	COG1660	Displays ATPase and GTPase activities
FE156_RS24730	COG1481	regulation of sporulation
FE156_RS24735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FE156_RS24740	COG0126	phosphoglycerate kinase activity
FE156_RS24745	COG0149	triose-phosphate isomerase activity
FE156_RS24750	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FE156_RS24760	COG0166	Belongs to the GPI family
FE156_RS24765	COG0363	glucosamine-6-phosphate deaminase activity
FE156_RS24780	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FE156_RS24785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FE156_RS24790	COG0109	protoheme IX farnesyltransferase activity
FE156_RS24815	COG1131	(ABC) transporter
FE156_RS24830	COG0719	Fe-S assembly protein
FE156_RS24840	COG0396	ATPase activity
FE156_RS24845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FE156_RS24850	COG0822	iron-sulfur transferase activity
FE156_RS24895	COG2197	response regulator
FE156_RS24900	COG4585	Histidine kinase
FE156_RS24930	COG1902	pentaerythritol trinitrate reductase activity
FE156_RS24940	COG1917	Cupin 2, conserved barrel domain protein
FE156_RS24950	COG0456	acetyltransferase
FE156_RS24955	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FE156_RS25000	COG1492	cobalamin metabolic process
FE156_RS25020	COG0235	Class ii aldolase
FE156_RS25045	COG0488	(ABC) transporter
FE156_RS25055	COG1024	Enoyl-CoA hydratase
FE156_RS25105	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FE156_RS25130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FE156_RS25145	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE156_RS25150	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FE156_RS25160	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FE156_RS25180	COG2261	transglycosylase associated protein
FE156_RS25185	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FE156_RS25195	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FE156_RS25205	COG2186	Transcriptional regulator
FE156_RS25210	COG2807	transmembrane transport
FE156_RS25225	COG3830	Belongs to the UPF0237 family
FE156_RS25225	COG0560	Phosphoserine phosphatase
FE156_RS25230	COG0842	Transport permease protein
FE156_RS25230	COG1131	(ABC) transporter
FE156_RS25230	COG1716	ATPase activity
FE156_RS25240	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FE156_RS25255	COG2197	response regulator
FE156_RS25270	COG1119	ATPase activity
FE156_RS25290	COG1881	PFAM PEBP family protein
FE156_RS25300	COG2094	Belongs to the DNA glycosylase MPG family
FE156_RS25340	COG0647	UMP catabolic process
FE156_RS25380	COG0438	transferase activity, transferring glycosyl groups
FE156_RS25400	COG3387	PFAM Glycoside hydrolase 15-related
FE156_RS25405	COG0504	CTP synthase activity
FE156_RS25410	COG0494	nUDIX hydrolase
FE156_RS25420	COG0686	Belongs to the AlaDH PNT family
FE156_RS25435	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FE156_RS25440	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FE156_RS25445	COG1187	pseudouridine synthase activity
FE156_RS25455	COG1397	ADP-ribosylglycohydrolase
FE156_RS25460	COG3541	Predicted nucleotidyltransferase
FE156_RS25475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FE156_RS25485	COG1160	GTP binding
FE156_RS25505	COG0438	transferase activity, transferring glycosyl groups
FE156_RS25535	COG0477	Major facilitator Superfamily
FE156_RS25540	COG1799	cell septum assembly
FE156_RS25555	COG0765	amino acid transport
FE156_RS25575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE156_RS25610	COG0587	DNA-directed DNA polymerase activity
FE156_RS25615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FE156_RS25690	COG1216	Glycosyl transferase, family 2
FE156_RS25710	COG2755	lipolytic protein G-D-S-L family
FE156_RS25715	COG2815	serine threonine protein kinase
FE156_RS25715	COG0515	serine threonine protein kinase
FE156_RS25730	COG3973	AAA domain
FE156_RS25735	COG2188	Transcriptional regulator
FE156_RS25740	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FE156_RS25760	COG1309	transcriptional regulator
FE156_RS25810	COG3876	Protein conserved in bacteria
FE156_RS25820	COG0488	(ABC) transporter
FE156_RS25825	COG0110	maltose O-acetyltransferase activity
FE156_RS25840	COG0318	PFAM AMP-dependent synthetase and ligase
FE156_RS25850	COG1960	acyl-CoA dehydrogenase activity
FE156_RS25870	COG2149	membrane
FE156_RS25875	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FE156_RS25915	COG3265	gluconokinase activity
FE156_RS25925	COG3012	SEC-C Motif Domain Protein
FE156_RS25930	COG3189	MarR family transcriptional regulator
FE156_RS25940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FE156_RS25975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE156_RS26005	COG0215	cysteine-tRNA ligase activity
FE156_RS26025	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FE156_RS26030	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FE156_RS26040	COG1410	methionine synthase
FE156_RS26040	COG0646	methionine synthase
FE156_RS26050	COG4166	transmembrane transport
FE156_RS26055	COG2197	response regulator
FE156_RS26065	COG0517	IMP dehydrogenase activity
FE156_RS26065	COG1994	Peptidase M50
FE156_RS26090	COG1222	aaa ATPase
FE156_RS26095	COG4122	O-methyltransferase activity
FE156_RS26105	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FE156_RS26110	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FE156_RS26160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FE156_RS26165	COG0805	protein transport
FE156_RS26180	COG2124	cytochrome p450
FE156_RS26210	COG0564	pseudouridine synthase activity
FE156_RS26230	COG1595	DNA-templated transcription, initiation
FE156_RS26240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FE156_RS26245	COG4175	Glycine betaine
FE156_RS26245	COG0517	IMP dehydrogenase activity
FE156_RS26270	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FE156_RS26275	COG0531	amino acid
FE156_RS26280	COG2186	Transcriptional regulator
FE156_RS26285	COG0174	glutamine synthetase
FE156_RS26290	COG1012	belongs to the aldehyde dehydrogenase family
FE156_RS26325	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FE156_RS26335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FE156_RS26340	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FE156_RS26345	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FE156_RS26350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FE156_RS26360	COG5002	protein histidine kinase activity
FE156_RS26365	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FE156_RS26370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE156_RS26370	COG0072	phenylalanine-tRNA ligase activity
FE156_RS26415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE156_RS26435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FE156_RS26435	COG0426	domain, Protein
FE156_RS26465	COG0667	Aldo Keto reductase
FE156_RS26505	COG0537	adenosine 5'-monophosphoramidase activity
FE156_RS26520	COG2249	NAD(P)H dehydrogenase (quinone) activity
FE156_RS26535	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS26550	COG0697	spore germination
FE156_RS26555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE156_RS26590	COG2838	Isocitrate dehydrogenase
FE156_RS26615	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FE156_RS26630	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FE156_RS26635	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FE156_RS26640	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FE156_RS26645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FE156_RS26650	COG1438	arginine binding
FE156_RS26655	COG4585	Histidine kinase
FE156_RS26660	COG2197	response regulator
FE156_RS26670	COG2409	Drug exporters of the RND superfamily
FE156_RS26675	COG0385	Bile acid
FE156_RS26685	COG0165	Argininosuccinate lyase
FE156_RS26710	COG0204	Acyl-transferase
FE156_RS26710	COG0318	PFAM AMP-dependent synthetase and ligase
FE156_RS26715	COG0584	glycerophosphoryl diester phosphodiesterase
FE156_RS26740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FE156_RS26745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FE156_RS26755	COG1464	Belongs to the NlpA lipoprotein family
FE156_RS26760	COG1464	Belongs to the NlpA lipoprotein family
FE156_RS26775	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FE156_RS26780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FE156_RS26780	COG1648	precorrin-2 dehydrogenase activity
FE156_RS26855	COG0456	acetyltransferase
FE156_RS26855	COG0454	-acetyltransferase
FE156_RS26910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FE156_RS26915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FE156_RS26930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FE156_RS26935	COG1560	Kdo2-lipid A biosynthetic process
FE156_RS26940	COG0438	transferase activity, transferring glycosyl groups
FE156_RS26950	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FE156_RS26955	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FE156_RS26960	COG0217	transcriptional regulatory protein
FE156_RS26965	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FE156_RS26970	COG0632	four-way junction helicase activity
FE156_RS26985	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE156_RS26990	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE156_RS26995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FE156_RS27000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE156_RS27010	COG1196	nuclear chromosome segregation
FE156_RS27015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FE156_RS27025	COG0124	histidyl-tRNA synthetase
FE156_RS27040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FE156_RS27055	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FE156_RS27060	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FE156_RS27070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FE156_RS27075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FE156_RS27080	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FE156_RS27085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FE156_RS27090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FE156_RS27100	COG0006	proline dipeptidase activity
FE156_RS27105	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FE156_RS27110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FE156_RS27120	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FE156_RS27125	COG0540	Belongs to the ATCase OTCase family
FE156_RS27130	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FE156_RS27140	COG0505	Belongs to the CarA family
FE156_RS27145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FE156_RS27150	COG0167	dihydroorotate dehydrogenase activity
FE156_RS27155	COG0284	orotidine-5'-phosphate decarboxylase activity
FE156_RS27170	COG1758	RNA polymerase activity
FE156_RS27180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FE156_RS27195	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FE156_RS27210	COG2318	DinB family
FE156_RS27215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FE156_RS27220	COG2390	Transcriptional regulator
FE156_RS27260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE156_RS27280	COG0697	spore germination
FE156_RS27285	COG2233	PERMEase
FE156_RS27295	COG0738	Major facilitator superfamily
FE156_RS27300	COG1940	carbohydrate kinase activity
FE156_RS27300	COG1846	Transcriptional regulator
FE156_RS27320	COG3201	nicotinamide mononucleotide transporter
FE156_RS27325	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FE156_RS27325	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FE156_RS27330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FE156_RS27335	COG0140	phosphoribosyl-ATP diphosphatase activity
FE156_RS27340	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FE156_RS27370	COG1960	acyl-CoA dehydrogenase activity
FE156_RS27395	COG0463	Glycosyl transferase, family 2
FE156_RS27410	COG2270	Major facilitator Superfamily
FE156_RS27420	COG2364	Membrane
FE156_RS27515	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FE156_RS27535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FE156_RS27545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FE156_RS27580	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FE156_RS27600	COG1716	ATPase activity
FE156_RS27620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FE156_RS27630	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FE156_RS27630	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FE156_RS27690	COG0697	spore germination
FE156_RS27705	COG0697	spore germination
FE156_RS27725	COG4251	negative regulation of phosphorylation
FE156_RS27775	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FE156_RS27825	COG1982	Orn Lys Arg decarboxylase major
FE156_RS27835	COG1968	undecaprenyl-diphosphatase activity
FE156_RS27855	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FE156_RS27910	COG0110	maltose O-acetyltransferase activity
FE156_RS27920	COG1832	CoA-binding protein
FE156_RS27925	COG1739	Uncharacterized protein family UPF0029
FE156_RS27945	COG1595	DNA-templated transcription, initiation
FE156_RS27960	COG0420	3'-5' exonuclease activity
FE156_RS27965	COG0419	ATPase involved in DNA repair
FE156_RS27970	COG1522	sequence-specific DNA binding
FE156_RS27980	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS27995	COG0626	cystathionine gamma-synthase activity
FE156_RS28020	COG2188	Transcriptional regulator
FE156_RS28025	COG1940	carbohydrate kinase activity
FE156_RS28045	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FE156_RS28075	COG0456	acetyltransferase
FE156_RS28080	COG0488	(ABC) transporter
FE156_RS28085	COG0488	(ABC) transporter
FE156_RS28095	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FE156_RS28105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FE156_RS28130	COG0791	NLP P60 protein
FE156_RS28135	COG0740	serine-type endopeptidase activity
FE156_RS28145	COG0831	urea catabolic process
FE156_RS28150	COG0832	Belongs to the urease beta subunit family
FE156_RS28155	COG0804	urea catabolic process
FE156_RS28165	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FE156_RS28170	COG0829	nickel cation binding
FE156_RS28175	COG4552	Acetyltransferase involved in intracellular survival and related
FE156_RS28180	COG0204	Acyl-transferase
FE156_RS28210	COG1132	(ABC) transporter
FE156_RS28225	COG2175	clavaminate synthase activity
FE156_RS28235	COG0435	Glutathione S-transferase
FE156_RS28255	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FE156_RS28260	COG0583	DNA-binding transcription factor activity
FE156_RS28280	COG0205	6-phosphofructokinase activity
FE156_RS28285	COG3442	glutamine amidotransferase
FE156_RS28305	COG1960	acyl-CoA dehydrogenase activity
FE156_RS28325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE156_RS28350	COG1175	transmembrane transport
FE156_RS28355	COG0395	ABC-type sugar transport system, permease component
FE156_RS28360	COG2723	6-phospho-beta-galactosidase activity
FE156_RS28365	COG0501	Belongs to the peptidase M48B family
FE156_RS28410	COG4251	negative regulation of phosphorylation
FE156_RS28415	COG0784	Response regulator, receiver
FE156_RS28435	COG0656	L-ascorbic acid biosynthetic process
FE156_RS28445	COG1595	DNA-templated transcription, initiation
FE156_RS28455	COG1132	(ABC) transporter
FE156_RS28480	COG3693	PFAM glycoside hydrolase, family 10
FE156_RS28490	COG1309	transcriptional regulator
FE156_RS28495	COG1131	(ABC) transporter
FE156_RS28500	COG3559	Exporter of polyketide antibiotics
FE156_RS28505	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FE156_RS28535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FE156_RS28540	COG3279	Response regulator of the LytR AlgR family
FE156_RS28550	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE156_RS28555	COG3275	phosphorelay sensor kinase activity
FE156_RS28620	COG0583	DNA-binding transcription factor activity
FE156_RS28630	COG1053	succinate dehydrogenase
FE156_RS28635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FE156_RS28640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE156_RS28650	COG3360	Dodecin
FE156_RS28655	COG2182	Extracellular solute-binding protein
FE156_RS28660	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FE156_RS28665	COG0121	glutamine amidotransferase
FE156_RS28670	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FE156_RS28690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FE156_RS28695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE156_RS28705	COG1959	2 iron, 2 sulfur cluster binding
FE156_RS28710	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS28735	COG2837	iron assimilation
FE156_RS28745	COG1796	DNA polymerase
FE156_RS28745	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FE156_RS28750	COG0142	geranyltranstransferase activity
FE156_RS28770	COG1733	regulation of RNA biosynthetic process
FE156_RS28780	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FE156_RS28790	COG2310	stress, protein
FE156_RS28805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FE156_RS28815	COG0254	rRNA binding
FE156_RS28820	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FE156_RS28825	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FE156_RS28830	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FE156_RS28905	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FE156_RS28945	COG4257	antibiotic catabolic process
FE156_RS28955	COG0803	Belongs to the bacterial solute-binding protein 9 family
FE156_RS28965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FE156_RS28970	COG1121	(ABC) transporter
FE156_RS28975	COG4608	Belongs to the ABC transporter superfamily
FE156_RS28990	COG0747	negative chemotaxis
FE156_RS29000	COG3458	cephalosporin-C deacetylase activity
FE156_RS29010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE156_RS29020	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FE156_RS29025	COG0363	glucosamine-6-phosphate deaminase activity
FE156_RS29030	COG0590	tRNA wobble adenosine to inosine editing
FE156_RS29035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FE156_RS29070	COG0300	oxidoreductase activity
FE156_RS29080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FE156_RS29130	COG0745	RESPONSE REGULATOR receiver
FE156_RS29135	COG0243	molybdopterin cofactor binding
FE156_RS29145	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE156_RS29145	COG2146	nitrite reductase [NAD(P)H] activity
FE156_RS29195	COG2188	Transcriptional regulator
FE156_RS29200	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FE156_RS29205	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FE156_RS29210	COG1984	allophanate hydrolase subunit 2
FE156_RS29230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE156_RS29240	COG1120	ATPase activity
FE156_RS29265	COG1132	(ABC) transporter
FE156_RS29275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FE156_RS29285	COG0110	maltose O-acetyltransferase activity
FE156_RS29295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FE156_RS29305	COG0494	nUDIX hydrolase
FE156_RS29325	COG0235	Class ii aldolase
FE156_RS29345	COG1116	anion transmembrane transporter activity
FE156_RS29355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FE156_RS29365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE156_RS29370	COG0583	DNA-binding transcription factor activity
FE156_RS29380	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS29400	COG2124	cytochrome p450
FE156_RS29405	COG1174	glycine betaine transport
FE156_RS29410	COG1174	glycine betaine transport
FE156_RS29420	COG0517	IMP dehydrogenase activity
FE156_RS29420	COG1125	glycine betaine transport
FE156_RS29450	COG1960	acyl-CoA dehydrogenase activity
FE156_RS29460	COG0601	transmembrane transport
FE156_RS29465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE156_RS29470	COG0444	Belongs to the ABC transporter superfamily
FE156_RS29475	COG1124	(ABC) transporter
FE156_RS29490	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
FE156_RS29495	COG2318	DinB family
FE156_RS29560	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS29625	COG3321	synthase
FE156_RS29625	COG0604	alcohol dehydrogenase
FE156_RS29630	COG3321	synthase
FE156_RS29630	COG0604	alcohol dehydrogenase
FE156_RS29705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE156_RS29715	COG1129	ABC transporter
FE156_RS29745	COG3483	tryptophan 2,3-dioxygenase activity
FE156_RS29750	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS29755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE156_RS29760	COG2151	metal-sulfur cluster biosynthetic enzyme
FE156_RS29765	COG3396	Phenylacetate-CoA oxygenase
FE156_RS29775	COG3396	Phenylacetate-CoA oxygenase
FE156_RS29790	COG0604	alcohol dehydrogenase
FE156_RS29800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FE156_RS29850	COG0515	serine threonine protein kinase
FE156_RS29880	COG1404	Belongs to the peptidase S8 family
FE156_RS29935	COG4335	DNA alkylation repair
FE156_RS29960	COG0477	Major facilitator Superfamily
FE156_RS29985	COG1309	transcriptional regulator
FE156_RS29990	COG3246	L-lysine catabolic process to acetate
FE156_RS29995	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE156_RS30020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FE156_RS30040	COG2318	DinB family
FE156_RS30060	COG2801	Transposase and inactivated derivatives
FE156_RS30075	COG0142	geranyltranstransferase activity
FE156_RS30080	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS30080	COG3321	synthase
FE156_RS30080	COG0604	alcohol dehydrogenase
FE156_RS30155	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FE156_RS30175	COG3321	synthase
FE156_RS30175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FE156_RS30175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FE156_RS30175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE156_RS30175	COG1028	Short-chain dehydrogenase reductase Sdr
FE156_RS30205	COG2197	response regulator
FE156_RS30240	COG1131	(ABC) transporter
FE156_RS30250	COG1819	glycosyl
FE156_RS30295	COG3321	synthase
FE156_RS30295	COG0604	alcohol dehydrogenase
FE156_RS30490	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FE156_RS30515	COG0151	Belongs to the GarS family
FE156_RS30525	COG2046	Belongs to the sulfate adenylyltransferase family
FE156_RS30525	COG0529	Catalyzes the synthesis of activated sulfate
FE156_RS30560	COG0477	Major facilitator Superfamily
FE156_RS30580	COG2124	cytochrome p450
FE156_RS30595	COG0604	alcohol dehydrogenase
FE156_RS30610	COG1819	glycosyl
FE156_RS30620	COG2723	6-phospho-beta-galactosidase activity
FE156_RS30635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FE156_RS30640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FE156_RS30645	COG3321	synthase
FE156_RS30645	COG0604	alcohol dehydrogenase
FE156_RS30655	COG3321	synthase
FE156_RS30655	COG0604	alcohol dehydrogenase