SMD11_RS23280 5e656584e8231b912baa786790383cf9 191 Pfam PF02342 TerD domain 3 187 6.4E-85 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS23280 5e656584e8231b912baa786790383cf9 191 Gene3D G3DSA:2.60.60.30 18 185 1.1E-74 T 06-07-2017 SMD11_RS16465 3814c6e42dfb78f556b38ade87d78797 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 2.6E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS16465 3814c6e42dfb78f556b38ade87d78797 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 2.6E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS16465 3814c6e42dfb78f556b38ade87d78797 236 SUPERFAMILY SSF46785 6 109 9.49E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16465 3814c6e42dfb78f556b38ade87d78797 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 8.7E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS16465 3814c6e42dfb78f556b38ade87d78797 236 Pfam PF07729 FCD domain 94 223 4.4E-23 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS16465 3814c6e42dfb78f556b38ade87d78797 236 Gene3D G3DSA:1.10.10.10 6 77 8.4E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16465 3814c6e42dfb78f556b38ade87d78797 236 Gene3D G3DSA:1.20.120.530 89 232 4.0E-29 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS16465 3814c6e42dfb78f556b38ade87d78797 236 SMART SM00345 15 74 4.7E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS16465 3814c6e42dfb78f556b38ade87d78797 236 SUPERFAMILY SSF48008 91 231 5.49E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS16465 3814c6e42dfb78f556b38ade87d78797 236 SMART SM00895 94 224 1.2E-24 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS32975 3c1ccdacd1fbc48ea1ef0ba6fb1b9b1b 343 SUPERFAMILY SSF55347 151 310 1.01E-32 T 06-07-2017 SMD11_RS32975 3c1ccdacd1fbc48ea1ef0ba6fb1b9b1b 343 Gene3D G3DSA:3.40.50.720 1 159 6.7E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32975 3c1ccdacd1fbc48ea1ef0ba6fb1b9b1b 343 SUPERFAMILY SSF51735 1 166 4.16E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32975 3c1ccdacd1fbc48ea1ef0ba6fb1b9b1b 343 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 342 4.4E-98 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS32975 3c1ccdacd1fbc48ea1ef0ba6fb1b9b1b 343 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 336 34.169 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS32975 3c1ccdacd1fbc48ea1ef0ba6fb1b9b1b 343 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 142 8.2E-24 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD11_RS32975 3c1ccdacd1fbc48ea1ef0ba6fb1b9b1b 343 Gene3D G3DSA:3.30.360.10 160 310 2.3E-34 T 06-07-2017 SMD11_RS32975 3c1ccdacd1fbc48ea1ef0ba6fb1b9b1b 343 SMART SM00859 3 143 1.9E-36 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD11_RS06590 31acefe147d9887034248aeeb5d0d8f2 469 Gene3D G3DSA:3.50.50.60 305 306 4.4E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS06590 31acefe147d9887034248aeeb5d0d8f2 469 Gene3D G3DSA:3.50.50.60 204 265 4.4E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS06590 31acefe147d9887034248aeeb5d0d8f2 469 Gene3D G3DSA:3.50.50.60 432 463 4.4E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS06590 31acefe147d9887034248aeeb5d0d8f2 469 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 3.6E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS06590 31acefe147d9887034248aeeb5d0d8f2 469 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 95 103 3.6E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS06590 31acefe147d9887034248aeeb5d0d8f2 469 Gene3D G3DSA:3.50.50.60 3 58 8.0E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS06590 31acefe147d9887034248aeeb5d0d8f2 469 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 53 9.8E-11 T 06-07-2017 SMD11_RS06590 31acefe147d9887034248aeeb5d0d8f2 469 SUPERFAMILY SSF51905 431 461 1.02E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS06590 31acefe147d9887034248aeeb5d0d8f2 469 SUPERFAMILY SSF51905 3 293 1.02E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS16110 e8de4420525d9f251a063ad59c989621 504 Gene3D G3DSA:1.20.1250.20 17 211 4.6E-34 T 06-07-2017 SMD11_RS16110 e8de4420525d9f251a063ad59c989621 504 Gene3D G3DSA:1.20.1250.20 269 433 3.6E-15 T 06-07-2017 SMD11_RS16110 e8de4420525d9f251a063ad59c989621 504 Gene3D G3DSA:1.20.1250.20 471 494 3.6E-15 T 06-07-2017 SMD11_RS16110 e8de4420525d9f251a063ad59c989621 504 Pfam PF07690 Major Facilitator Superfamily 30 422 2.3E-51 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS16110 e8de4420525d9f251a063ad59c989621 504 PRINTS PR01036 Tetracycline resistance protein TetB signature 29 53 3.4E-11 T 06-07-2017 SMD11_RS16110 e8de4420525d9f251a063ad59c989621 504 PRINTS PR01036 Tetracycline resistance protein TetB signature 89 111 3.4E-11 T 06-07-2017 SMD11_RS16110 e8de4420525d9f251a063ad59c989621 504 PRINTS PR01036 Tetracycline resistance protein TetB signature 413 432 3.4E-11 T 06-07-2017 SMD11_RS16110 e8de4420525d9f251a063ad59c989621 504 PRINTS PR01036 Tetracycline resistance protein TetB signature 150 174 3.4E-11 T 06-07-2017 SMD11_RS16110 e8de4420525d9f251a063ad59c989621 504 SUPERFAMILY SSF103473 470 499 3.66E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS16110 e8de4420525d9f251a063ad59c989621 504 SUPERFAMILY SSF103473 260 432 3.66E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS16110 e8de4420525d9f251a063ad59c989621 504 SUPERFAMILY SSF103473 9 212 3.66E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS16110 e8de4420525d9f251a063ad59c989621 504 ProSitePatterns PS00216 Sugar transport proteins signature 1. 80 96 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS02785 547b487b42965bf10560c310fbaa09b6 169 SUPERFAMILY SSF55961 5 163 6.53E-6 T 06-07-2017 SMD11_RS02785 547b487b42965bf10560c310fbaa09b6 169 Pfam PF10698 Protein of unknown function (DUF2505) 9 144 3.8E-6 T 06-07-2017 IPR019639 Protein of unknown function DUF2505 SMD11_RS11890 805e21df5f73f1ff2c07a30ab66f7e41 109 PRINTS PR00354 7Fe ferredoxin signature 9 19 4.1E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 SMD11_RS11890 805e21df5f73f1ff2c07a30ab66f7e41 109 PRINTS PR00354 7Fe ferredoxin signature 19 29 4.1E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 SMD11_RS11890 805e21df5f73f1ff2c07a30ab66f7e41 109 PRINTS PR00354 7Fe ferredoxin signature 35 52 4.1E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 SMD11_RS11890 805e21df5f73f1ff2c07a30ab66f7e41 109 Pfam PF00037 4Fe-4S binding domain 34 55 1.3E-8 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD11_RS11890 805e21df5f73f1ff2c07a30ab66f7e41 109 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD11_RS11890 805e21df5f73f1ff2c07a30ab66f7e41 109 Gene3D G3DSA:3.30.70.20 3 76 1.6E-19 T 06-07-2017 SMD11_RS11890 805e21df5f73f1ff2c07a30ab66f7e41 109 SUPERFAMILY SSF54862 3 89 3.63E-22 T 06-07-2017 SMD11_RS15945 a84c44cdcd8653cba1b91861be901c6d 515 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 79 348 1.6E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15945 a84c44cdcd8653cba1b91861be901c6d 515 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 309 331 6.4E-19 T 06-07-2017 SMD11_RS15945 a84c44cdcd8653cba1b91861be901c6d 515 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 6.4E-19 T 06-07-2017 SMD11_RS15945 a84c44cdcd8653cba1b91861be901c6d 515 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 78 97 6.4E-19 T 06-07-2017 SMD11_RS15945 a84c44cdcd8653cba1b91861be901c6d 515 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 203 221 6.4E-19 T 06-07-2017 SMD11_RS15945 a84c44cdcd8653cba1b91861be901c6d 515 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 300 6.4E-19 T 06-07-2017 SMD11_RS15945 a84c44cdcd8653cba1b91861be901c6d 515 Gene3D G3DSA:3.50.50.60 78 172 6.5E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15945 a84c44cdcd8653cba1b91861be901c6d 515 Gene3D G3DSA:3.50.50.60 173 350 3.9E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15945 a84c44cdcd8653cba1b91861be901c6d 515 Pfam PF04324 BFD-like [2Fe-2S] binding domain 462 508 2.1E-11 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain SMD11_RS15945 a84c44cdcd8653cba1b91861be901c6d 515 SUPERFAMILY SSF51905 79 356 1.46E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15945 a84c44cdcd8653cba1b91861be901c6d 515 Gene3D G3DSA:3.30.390.30 376 442 7.1E-6 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD11_RS15945 a84c44cdcd8653cba1b91861be901c6d 515 SUPERFAMILY SSF55424 375 442 2.61E-6 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD11_RS19905 d0cde1f39390cb8e291f1acc57618cfb 421 Pfam PF00512 His Kinase A (phospho-acceptor) domain 202 257 1.6E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS19905 d0cde1f39390cb8e291f1acc57618cfb 421 Pfam PF00672 HAMP domain 126 195 1.5E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS19905 d0cde1f39390cb8e291f1acc57618cfb 421 SUPERFAMILY SSF47384 183 256 5.49E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS19905 d0cde1f39390cb8e291f1acc57618cfb 421 SMART SM00387 303 403 4.3E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS19905 d0cde1f39390cb8e291f1acc57618cfb 421 Gene3D G3DSA:1.10.287.130 190 254 9.6E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS19905 d0cde1f39390cb8e291f1acc57618cfb 421 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 304 400 1.2E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS19905 d0cde1f39390cb8e291f1acc57618cfb 421 SMART SM00304 146 199 3.9E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS19905 d0cde1f39390cb8e291f1acc57618cfb 421 Gene3D G3DSA:3.30.565.10 270 399 1.6E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS19905 d0cde1f39390cb8e291f1acc57618cfb 421 SMART SM00388 200 258 1.6E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS19905 d0cde1f39390cb8e291f1acc57618cfb 421 SUPERFAMILY SSF55874 247 399 2.88E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS19905 d0cde1f39390cb8e291f1acc57618cfb 421 SUPERFAMILY SSF158472 150 195 1.01E-7 T 06-07-2017 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 PRINTS PR00385 P450 superfamily signature 404 413 9.9E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 PRINTS PR00385 P450 superfamily signature 273 290 9.9E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 PRINTS PR00385 P450 superfamily signature 413 424 9.9E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 PRINTS PR00385 P450 superfamily signature 328 339 9.9E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 Gene3D G3DSA:3.40.50.80 928 1072 1.9E-41 T 06-07-2017 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 Gene3D G3DSA:3.40.50.360 496 643 5.8E-35 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 SUPERFAMILY SSF48264 12 464 7.07E-101 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 406 415 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 Gene3D G3DSA:2.40.30.10 687 720 4.7E-21 T 06-07-2017 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 Gene3D G3DSA:2.40.30.10 855 927 4.7E-21 T 06-07-2017 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 Pfam PF00667 FAD binding domain 689 897 2.6E-37 T 06-07-2017 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 Gene3D G3DSA:1.10.630.10 11 465 3.5E-107 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 Pfam PF00258 Flavodoxin 498 623 1.9E-17 T 06-07-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 Gene3D G3DSA:1.20.990.10 721 854 2.5E-30 T 06-07-2017 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 GO:0016491|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 SUPERFAMILY SSF52343 917 1072 1.57E-36 T 06-07-2017 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 PIRSF PIRSF000209 6 1074 0.0 T 06-07-2017 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 KEGG: 00071+1.14.14.1|KEGG: 00140+1.14.14.1|KEGG: 00232+1.14.14.1|KEGG: 00380+1.14.14.1|KEGG: 00590+1.14.14.1|KEGG: 00591+1.14.14.1|KEGG: 00627+1.14.14.1|KEGG: 00830+1.14.14.1|KEGG: 00980+1.14.14.1|KEGG: 00982+1.14.14.1|MetaCyc: PWY-5451|MetaCyc: PWY-5665|MetaCyc: PWY-6398|MetaCyc: PWY-6992|MetaCyc: PWY-7466 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 SUPERFAMILY SSF63380 681 911 8.26E-53 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 PRINTS PR00463 E-class P450 group I signature 262 279 1.1E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 PRINTS PR00463 E-class P450 group I signature 368 392 1.1E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 PRINTS PR00463 E-class P450 group I signature 41 60 1.1E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 PRINTS PR00463 E-class P450 group I signature 282 308 1.1E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 PRINTS PR00463 E-class P450 group I signature 413 436 1.1E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 PRINTS PR00463 E-class P450 group I signature 403 413 1.1E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 Pfam PF00067 Cytochrome P450 15 459 5.0E-80 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 SUPERFAMILY SSF52218 496 644 2.79E-34 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS00995 ba866dc1632cd79e0826d440e55a3f48 1074 Pfam PF00175 Oxidoreductase NAD-binding domain 930 1036 2.0E-10 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMD11_RS00750 e3fb8d34ad135fbaca133e2015529c35 411 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 353 362 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS00750 e3fb8d34ad135fbaca133e2015529c35 411 Gene3D G3DSA:1.10.630.10 4 411 2.2E-97 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00750 e3fb8d34ad135fbaca133e2015529c35 411 PRINTS PR00359 B-class P450 signature 149 165 8.8E-30 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00750 e3fb8d34ad135fbaca133e2015529c35 411 PRINTS PR00359 B-class P450 signature 330 345 8.8E-30 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00750 e3fb8d34ad135fbaca133e2015529c35 411 PRINTS PR00359 B-class P450 signature 284 295 8.8E-30 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00750 e3fb8d34ad135fbaca133e2015529c35 411 PRINTS PR00359 B-class P450 signature 203 225 8.8E-30 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00750 e3fb8d34ad135fbaca133e2015529c35 411 PRINTS PR00359 B-class P450 signature 351 360 8.8E-30 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00750 e3fb8d34ad135fbaca133e2015529c35 411 PRINTS PR00359 B-class P450 signature 102 113 8.8E-30 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00750 e3fb8d34ad135fbaca133e2015529c35 411 PRINTS PR00359 B-class P450 signature 302 329 8.8E-30 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00750 e3fb8d34ad135fbaca133e2015529c35 411 PRINTS PR00359 B-class P450 signature 360 371 8.8E-30 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00750 e3fb8d34ad135fbaca133e2015529c35 411 SUPERFAMILY SSF48264 10 411 2.1E-75 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00750 e3fb8d34ad135fbaca133e2015529c35 411 Pfam PF00067 Cytochrome P450 197 383 7.7E-21 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20465 4f1aca6811942a6f46fc54a5157664dc 464 Gene3D G3DSA:3.40.50.1100 43 147 9.6E-40 T 06-07-2017 SMD11_RS20465 4f1aca6811942a6f46fc54a5157664dc 464 SUPERFAMILY SSF54631 325 458 1.64E-15 T 06-07-2017 SMD11_RS20465 4f1aca6811942a6f46fc54a5157664dc 464 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 SMD11_RS20465 4f1aca6811942a6f46fc54a5157664dc 464 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 4 457 3.5E-210 T 06-07-2017 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 SMD11_RS20465 4f1aca6811942a6f46fc54a5157664dc 464 Gene3D G3DSA:3.10.580.10 338 458 3.1E-19 T 06-07-2017 SMD11_RS20465 4f1aca6811942a6f46fc54a5157664dc 464 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 296 3.1E-71 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS20465 4f1aca6811942a6f46fc54a5157664dc 464 Gene3D G3DSA:3.40.50.1100 3 42 2.2E-71 T 06-07-2017 SMD11_RS20465 4f1aca6811942a6f46fc54a5157664dc 464 Gene3D G3DSA:3.40.50.1100 153 313 2.2E-71 T 06-07-2017 SMD11_RS20465 4f1aca6811942a6f46fc54a5157664dc 464 Pfam PF00571 CBS domain 339 394 5.6E-5 T 06-07-2017 IPR000644 CBS domain SMD11_RS20465 4f1aca6811942a6f46fc54a5157664dc 464 Pfam PF00571 CBS domain 410 457 0.0027 T 06-07-2017 IPR000644 CBS domain SMD11_RS20465 4f1aca6811942a6f46fc54a5157664dc 464 SUPERFAMILY SSF53686 2 317 5.76E-98 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS20465 4f1aca6811942a6f46fc54a5157664dc 464 SMART SM00116 339 395 0.23 T 06-07-2017 IPR000644 CBS domain SMD11_RS20465 4f1aca6811942a6f46fc54a5157664dc 464 SMART SM00116 412 457 1.9 T 06-07-2017 IPR000644 CBS domain SMD11_RS18525 7b0feba24ab293c2dee1a5fe96093c26 210 Gene3D G3DSA:2.150.10.10 69 183 9.7E-6 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal SMD11_RS18525 7b0feba24ab293c2dee1a5fe96093c26 210 PRINTS PR00313 NodO calcium binding signature 132 140 8.0E-6 T 06-07-2017 SMD11_RS18525 7b0feba24ab293c2dee1a5fe96093c26 210 PRINTS PR00313 NodO calcium binding signature 87 98 8.0E-6 T 06-07-2017 SMD11_RS18525 7b0feba24ab293c2dee1a5fe96093c26 210 PRINTS PR00313 NodO calcium binding signature 109 117 8.0E-6 T 06-07-2017 SMD11_RS18525 7b0feba24ab293c2dee1a5fe96093c26 210 PRINTS PR00313 NodO calcium binding signature 153 162 8.0E-6 T 06-07-2017 SMD11_RS18525 7b0feba24ab293c2dee1a5fe96093c26 210 SUPERFAMILY SSF51120 69 187 8.5E-8 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal SMD11_RS21295 e8c69f1d5811d5be480925f5ad4ee90a 413 Gene3D G3DSA:1.10.287.130 192 246 3.4E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS21295 e8c69f1d5811d5be480925f5ad4ee90a 413 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 260 9.1E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS21295 e8c69f1d5811d5be480925f5ad4ee90a 413 SUPERFAMILY SSF55874 249 405 2.49E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS21295 e8c69f1d5811d5be480925f5ad4ee90a 413 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 305 406 5.9E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS21295 e8c69f1d5811d5be480925f5ad4ee90a 413 SMART SM00304 147 201 9.0E-4 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS21295 e8c69f1d5811d5be480925f5ad4ee90a 413 SMART SM00387 304 407 7.5E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS21295 e8c69f1d5811d5be480925f5ad4ee90a 413 SMART SM00388 202 260 2.6E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS21295 e8c69f1d5811d5be480925f5ad4ee90a 413 SUPERFAMILY SSF47384 186 261 3.73E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS21295 e8c69f1d5811d5be480925f5ad4ee90a 413 Gene3D G3DSA:3.30.565.10 247 406 1.8E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS21295 e8c69f1d5811d5be480925f5ad4ee90a 413 Pfam PF00672 HAMP domain 127 197 1.1E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS32305 ea12c1747c46923aea992052a878acb5 458 Gene3D G3DSA:3.30.1870.10 112 185 9.6E-17 T 06-07-2017 SMD11_RS32305 ea12c1747c46923aea992052a878acb5 458 Gene3D G3DSA:1.20.1440.30 188 314 9.7E-24 T 06-07-2017 SMD11_RS32305 ea12c1747c46923aea992052a878acb5 458 SUPERFAMILY SSF159501 44 454 2.62E-88 T 06-07-2017 SMD11_RS32305 ea12c1747c46923aea992052a878acb5 458 Gene3D G3DSA:3.40.1660.10 44 110 2.1E-44 T 06-07-2017 SMD11_RS32305 ea12c1747c46923aea992052a878acb5 458 Gene3D G3DSA:3.40.1660.10 316 454 2.1E-44 T 06-07-2017 SMD11_RS32305 ea12c1747c46923aea992052a878acb5 458 PIRSF PIRSF036794 31 457 1.2E-94 T 06-07-2017 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type SMD11_RS32305 ea12c1747c46923aea992052a878acb5 458 Pfam PF05139 Erythromycin esterase 109 448 1.6E-61 T 06-07-2017 IPR007815 Erythromycin esterase GO:0046677 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 Gene3D G3DSA:3.30.470.20 248 345 3.7E-33 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 Gene3D G3DSA:1.10.189.10 346 403 6.1E-24 T 06-07-2017 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 452 463 - T 06-07-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 Gene3D G3DSA:3.50.30.10 404 509 7.6E-38 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 SUPERFAMILY SSF52009 390 515 2.75E-34 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 PIRSF PIRSF000853 7 902 0.0 T 06-07-2017 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 SUPERFAMILY SSF51621 542 894 9.62E-114 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 8 895 0.0 T 06-07-2017 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 Gene3D G3DSA:3.30.1490.20 9 115 2.8E-56 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 Gene3D G3DSA:3.30.1490.20 204 247 2.8E-56 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 SUPERFAMILY SSF56059 6 381 9.18E-131 T 06-07-2017 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 539 892 2.8E-85 T 06-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 Gene3D G3DSA:3.20.20.60 553 895 2.8E-128 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 Pfam PF00391 PEP-utilising enzyme, mobile domain 424 506 2.1E-25 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 300 355 7.3E-9 T 06-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 23 291 8.6E-41 T 06-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SMD11_RS22940 02a7c48189808d700756ebb1908e14e4 904 Gene3D G3DSA:1.20.80.30 116 202 1.5E-34 T 06-07-2017 SMD11_RS31780 60df0aeaa01657f5e65809e911f3e99e 210 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 89 5.0E-31 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMD11_RS31780 60df0aeaa01657f5e65809e911f3e99e 210 Pfam PF01386 Ribosomal L25p family 6 90 2.3E-24 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMD11_RS31780 60df0aeaa01657f5e65809e911f3e99e 210 Gene3D G3DSA:2.170.120.20 95 185 7.1E-24 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain SMD11_RS31780 60df0aeaa01657f5e65809e911f3e99e 210 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 178 5.1E-21 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain SMD11_RS31780 60df0aeaa01657f5e65809e911f3e99e 210 Gene3D G3DSA:2.40.240.10 4 93 9.5E-29 T 06-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMD11_RS31780 60df0aeaa01657f5e65809e911f3e99e 210 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 179 26.449 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMD11_RS31780 60df0aeaa01657f5e65809e911f3e99e 210 SUPERFAMILY SSF50715 4 185 1.55E-51 T 06-07-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMD11_RS31780 60df0aeaa01657f5e65809e911f3e99e 210 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 176 4.1E-43 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMD11_RS09585 c19d1838a9f73a386a0e2e876e2ecaeb 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 06-07-2017 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS09585 c19d1838a9f73a386a0e2e876e2ecaeb 115 PRINTS PR00061 Ribosomal protein L19 signature 87 112 1.1E-42 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09585 c19d1838a9f73a386a0e2e876e2ecaeb 115 PRINTS PR00061 Ribosomal protein L19 signature 3 32 1.1E-42 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09585 c19d1838a9f73a386a0e2e876e2ecaeb 115 PRINTS PR00061 Ribosomal protein L19 signature 33 62 1.1E-42 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09585 c19d1838a9f73a386a0e2e876e2ecaeb 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 112 2.2E-48 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09585 c19d1838a9f73a386a0e2e876e2ecaeb 115 SUPERFAMILY SSF50104 1 114 5.21E-45 T 06-07-2017 IPR008991 Translation protein SH3-like domain SMD11_RS09585 c19d1838a9f73a386a0e2e876e2ecaeb 115 Pfam PF01245 Ribosomal protein L19 3 112 3.5E-49 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09585 c19d1838a9f73a386a0e2e876e2ecaeb 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 29.009 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09585 c19d1838a9f73a386a0e2e876e2ecaeb 115 PIRSF PIRSF002191 1 115 1.7E-48 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1126 1311 1.3E-49 T 06-07-2017 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SUPERFAMILY SSF53901 448 469 1.35E-89 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SUPERFAMILY SSF53901 32 406 1.35E-89 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Gene3D G3DSA:1.10.1200.10 1390 1464 4.5E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Gene3D G3DSA:1.10.1200.10 2419 2488 6.0E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SMART SM00823 Phosphopantetheine attachment site 1394 1464 3.0E-8 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SMART SM00823 Phosphopantetheine attachment site 2418 2489 1.9E-12 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Gene3D G3DSA:3.40.47.10 32 294 3.2E-98 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Gene3D G3DSA:3.40.47.10 1502 1768 4.3E-73 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SMART SM01294 2419 2485 3.1E-4 T 06-07-2017 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Pfam PF08659 KR domain 1126 1310 3.8E-55 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Pfam PF00550 Phosphopantetheine attachment site 2420 2485 6.8E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Pfam PF00550 Phosphopantetheine attachment site 1396 1459 5.6E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Gene3D G3DSA:3.40.47.10 2530 2784 2.1E-87 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SUPERFAMILY SSF47336 1391 1519 2.49E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SUPERFAMILY SSF53901 2929 2950 3.64E-80 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SUPERFAMILY SSF53901 2526 2888 3.64E-80 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Gene3D G3DSA:3.40.50.720 1124 1348 1.0E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1420 1435 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 282 4.5E-91 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1506 1756 4.9E-71 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2529 2770 1.5E-79 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SUPERFAMILY SSF53901 1918 1933 4.25E-79 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SUPERFAMILY SSF53901 1651 1874 4.25E-79 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SUPERFAMILY SSF53901 1502 1624 4.25E-79 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Pfam PF14765 Polyketide synthase dehydratase 2141 2372 6.2E-9 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Pfam PF14765 Polyketide synthase dehydratase 653 931 1.1E-53 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 417 514 1.9E-13 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2899 3023 5.0E-14 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1885 1996 8.2E-10 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2779 2895 5.0E-37 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1764 1880 1.7E-38 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 290 414 2.1E-36 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2684 2700 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SMART SM00825 Beta-ketoacyl synthase 1507 1943 5.2E-145 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SMART SM00825 Beta-ketoacyl synthase 2530 2954 1.4E-181 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SMART SM00825 Beta-ketoacyl synthase 36 473 4.2E-188 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SUPERFAMILY SSF51735 1122 1378 9.39E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Gene3D G3DSA:3.40.47.10 1769 1942 2.1E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Gene3D G3DSA:3.40.47.10 2785 2954 1.1E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 Gene3D G3DSA:3.40.47.10 295 471 1.5E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SUPERFAMILY SSF47336 2419 2542 3.93E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29970 1ff49d269fb0a218a5214e123de4687e 3136 SMART SM00826 653 825 2.8E-22 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS24790 c8886942e07ee32a9f9308299c6135c8 486 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 40 131 4.0E-20 T 06-07-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 SMD11_RS24790 c8886942e07ee32a9f9308299c6135c8 486 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 6.7E-25 T 06-07-2017 SMD11_RS24790 c8886942e07ee32a9f9308299c6135c8 486 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 6.7E-25 T 06-07-2017 SMD11_RS24790 c8886942e07ee32a9f9308299c6135c8 486 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 6.7E-25 T 06-07-2017 SMD11_RS24790 c8886942e07ee32a9f9308299c6135c8 486 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 6.7E-25 T 06-07-2017 SMD11_RS24790 c8886942e07ee32a9f9308299c6135c8 486 Gene3D G3DSA:1.10.1060.10 2 146 7.4E-36 T 06-07-2017 SMD11_RS24790 c8886942e07ee32a9f9308299c6135c8 486 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 456 1.9E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24790 c8886942e07ee32a9f9308299c6135c8 486 SUPERFAMILY SSF51971 361 467 2.71E-10 T 06-07-2017 SMD11_RS24790 c8886942e07ee32a9f9308299c6135c8 486 Gene3D G3DSA:3.50.50.60 237 385 2.2E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24790 c8886942e07ee32a9f9308299c6135c8 486 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 474 1.0E-209 T 06-07-2017 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 SMD11_RS24790 c8886942e07ee32a9f9308299c6135c8 486 Gene3D G3DSA:3.50.50.60 147 236 2.3E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24790 c8886942e07ee32a9f9308299c6135c8 486 Gene3D G3DSA:3.50.50.60 386 465 1.0E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24790 c8886942e07ee32a9f9308299c6135c8 486 SUPERFAMILY SSF46548 6 155 4.18E-35 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 SMD11_RS24790 c8886942e07ee32a9f9308299c6135c8 486 SUPERFAMILY SSF51971 144 400 2.53E-66 T 06-07-2017 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 SUPERFAMILY SSF51412 895 1112 9.77E-40 T 06-07-2017 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 SUPERFAMILY SSF51412 824 860 9.77E-40 T 06-07-2017 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 SUPERFAMILY SSF56112 5 287 7.96E-76 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 SMART SM00220 11 284 1.6E-67 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 Pfam PF13374 Tetratricopeptide repeat 515 556 2.8E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 Pfam PF13374 Tetratricopeptide repeat 641 682 6.5E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 Pfam PF13374 Tetratricopeptide repeat 397 430 0.012 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 SUPERFAMILY SSF48452 398 535 1.76E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 Gene3D G3DSA:3.30.200.20 5 82 5.5E-24 T 06-07-2017 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 Gene3D G3DSA:1.10.510.10 83 274 4.5E-48 T 06-07-2017 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 SUPERFAMILY SSF48452 636 755 1.21E-17 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 Pfam PF03060 Nitronate monooxygenase 818 1152 4.7E-43 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 Pfam PF00069 Protein kinase domain 11 280 3.6E-47 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 Pfam PF13424 Tetratricopeptide repeat 438 505 1.7E-8 T 06-07-2017 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 Pfam PF13424 Tetratricopeptide repeat 558 626 7.6E-13 T 06-07-2017 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 Pfam PF13424 Tetratricopeptide repeat 689 757 5.0E-14 T 06-07-2017 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 SUPERFAMILY SSF48452 510 662 2.28E-22 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 Gene3D G3DSA:3.20.20.70 908 1147 6.2E-49 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 Gene3D G3DSA:3.20.20.70 803 873 6.2E-49 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS29070 2a8c22ba442b0e417dd4d3871c852916 1277 Gene3D G3DSA:1.25.40.10 426 755 2.7E-34 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS18440 230bf44dc726f7de0fefd38fe97bffcf 387 Gene3D G3DSA:3.20.20.70 17 360 4.0E-54 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS18440 230bf44dc726f7de0fefd38fe97bffcf 387 Pfam PF04055 Radical SAM superfamily 61 232 1.0E-10 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS18440 230bf44dc726f7de0fefd38fe97bffcf 387 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 7 371 47.968 T 06-07-2017 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMD11_RS18440 230bf44dc726f7de0fefd38fe97bffcf 387 PIRSF PIRSF004762 1 380 5.7E-99 T 06-07-2017 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD11_RS18440 230bf44dc726f7de0fefd38fe97bffcf 387 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 10 368 2.7E-162 T 06-07-2017 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMD11_RS18440 230bf44dc726f7de0fefd38fe97bffcf 387 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 52 368 5.5E-91 T 06-07-2017 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD11_RS18440 230bf44dc726f7de0fefd38fe97bffcf 387 SUPERFAMILY SSF102114 16 361 1.57E-42 T 06-07-2017 SMD11_RS18820 a8dfcebcd4ec7c592176ee0dcbb0bd95 144 Gene3D G3DSA:1.10.10.250 75 143 1.1E-32 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SMD11_RS18820 a8dfcebcd4ec7c592176ee0dcbb0bd95 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 39 76 2.0E-16 T 06-07-2017 SMD11_RS18820 a8dfcebcd4ec7c592176ee0dcbb0bd95 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 129 144 - T 06-07-2017 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18820 a8dfcebcd4ec7c592176ee0dcbb0bd95 144 SUPERFAMILY SSF54747 5 75 4.71E-30 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal SMD11_RS18820 a8dfcebcd4ec7c592176ee0dcbb0bd95 144 SUPERFAMILY SSF46906 70 143 3.01E-27 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SMD11_RS18820 a8dfcebcd4ec7c592176ee0dcbb0bd95 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 6 143 3.1E-63 T 06-07-2017 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18820 a8dfcebcd4ec7c592176ee0dcbb0bd95 144 SMART SM00649 12 143 3.1E-87 T 06-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 SMD11_RS18820 a8dfcebcd4ec7c592176ee0dcbb0bd95 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 8 144 31.711 T 06-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 SMD11_RS18820 a8dfcebcd4ec7c592176ee0dcbb0bd95 144 Gene3D G3DSA:3.30.1550.10 5 74 3.1E-38 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal SMD11_RS18820 a8dfcebcd4ec7c592176ee0dcbb0bd95 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 12 69 2.0E-29 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal SMD11_RS18820 a8dfcebcd4ec7c592176ee0dcbb0bd95 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 74 142 1.4E-25 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SMD11_RS25120 25c91973933d47798a87fbf0508a071c 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 153 2.9E-59 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25120 25c91973933d47798a87fbf0508a071c 334 Gene3D G3DSA:3.40.50.720 2 161 1.4E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS25120 25c91973933d47798a87fbf0508a071c 334 SMART SM00846 3 153 1.3E-92 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25120 25c91973933d47798a87fbf0508a071c 334 SUPERFAMILY SSF55347 153 314 5.36E-70 T 06-07-2017 SMD11_RS25120 25c91973933d47798a87fbf0508a071c 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 1.4E-137 T 06-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25120 25c91973933d47798a87fbf0508a071c 334 Gene3D G3DSA:3.30.360.10 162 315 2.6E-74 T 06-07-2017 SMD11_RS25120 25c91973933d47798a87fbf0508a071c 334 PIRSF PIRSF000149 1 332 2.2E-134 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25120 25c91973933d47798a87fbf0508a071c 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 313 1.4E-68 T 06-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25120 25c91973933d47798a87fbf0508a071c 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 2.8E-40 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25120 25c91973933d47798a87fbf0508a071c 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 2.8E-40 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25120 25c91973933d47798a87fbf0508a071c 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 2.8E-40 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25120 25c91973933d47798a87fbf0508a071c 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 2.8E-40 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25120 25c91973933d47798a87fbf0508a071c 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 2.8E-40 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25120 25c91973933d47798a87fbf0508a071c 334 SUPERFAMILY SSF51735 2 179 9.06E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS15615 a0a91efdbff9fe51b1f7d18e81948e3c 423 SUPERFAMILY SSF55021 335 409 9.82E-22 T 06-07-2017 SMD11_RS15615 a0a91efdbff9fe51b1f7d18e81948e3c 423 Pfam PF13840 ACT domain 342 403 2.6E-12 T 06-07-2017 IPR027795 GATS-like ACT domain SMD11_RS15615 a0a91efdbff9fe51b1f7d18e81948e3c 423 Gene3D G3DSA:3.40.1160.10 3 244 2.3E-70 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS15615 a0a91efdbff9fe51b1f7d18e81948e3c 423 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 06-07-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD11_RS15615 a0a91efdbff9fe51b1f7d18e81948e3c 423 Pfam PF01842 ACT domain 269 329 3.2E-9 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 SMD11_RS15615 a0a91efdbff9fe51b1f7d18e81948e3c 423 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 407 9.8E-125 T 06-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD11_RS15615 a0a91efdbff9fe51b1f7d18e81948e3c 423 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 407 1.5E-117 T 06-07-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD11_RS15615 a0a91efdbff9fe51b1f7d18e81948e3c 423 SUPERFAMILY SSF53633 4 244 9.95E-71 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS15615 a0a91efdbff9fe51b1f7d18e81948e3c 423 Pfam PF00696 Amino acid kinase family 3 231 8.9E-55 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS15615 a0a91efdbff9fe51b1f7d18e81948e3c 423 Gene3D G3DSA:3.30.70.260 267 337 0.001 T 06-07-2017 SMD11_RS15615 a0a91efdbff9fe51b1f7d18e81948e3c 423 SUPERFAMILY SSF55021 251 331 1.03E-19 T 06-07-2017 SMD11_RS15615 a0a91efdbff9fe51b1f7d18e81948e3c 423 PIRSF PIRSF000726 60 415 4.5E-128 T 06-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD11_RS18720 6ea3f7faea69d289a3964f08bde88180 666 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 8 658 1.6E-137 T 06-07-2017 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18720 6ea3f7faea69d289a3964f08bde88180 666 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 86 106 1.5E-6 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMD11_RS18720 6ea3f7faea69d289a3964f08bde88180 666 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 359 381 1.5E-6 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMD11_RS18720 6ea3f7faea69d289a3964f08bde88180 666 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 264 286 1.5E-6 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMD11_RS18720 6ea3f7faea69d289a3964f08bde88180 666 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 601 627 1.5E-6 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMD11_RS18720 6ea3f7faea69d289a3964f08bde88180 666 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 71 122 9.2E-10 T 06-07-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18720 6ea3f7faea69d289a3964f08bde88180 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 7.1E-48 T 06-07-2017 SMD11_RS18720 6ea3f7faea69d289a3964f08bde88180 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 7.1E-48 T 06-07-2017 SMD11_RS18720 6ea3f7faea69d289a3964f08bde88180 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 7.1E-48 T 06-07-2017 SMD11_RS18720 6ea3f7faea69d289a3964f08bde88180 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 7.1E-48 T 06-07-2017 SMD11_RS18720 6ea3f7faea69d289a3964f08bde88180 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 246 272 7.1E-48 T 06-07-2017 SMD11_RS18720 6ea3f7faea69d289a3964f08bde88180 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 429 448 7.1E-48 T 06-07-2017 SMD11_RS18720 6ea3f7faea69d289a3964f08bde88180 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 314 326 7.1E-48 T 06-07-2017 SMD11_RS18720 6ea3f7faea69d289a3964f08bde88180 666 Pfam PF00361 Proton-conducting membrane transporter 135 406 5.3E-75 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS03590 4ae613912a86b127a1048c4f7c8d9dbf 263 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 254 2.0E-36 T 06-07-2017 IPR007404 LexA-binding, inner membrane-associated putative hydrolase SMD11_RS11645 6b39d0b4dba8ee848e4bcb99105d5a13 392 Pfam PF00899 ThiF family 21 254 1.3E-66 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SMD11_RS11645 6b39d0b4dba8ee848e4bcb99105d5a13 392 Pfam PF00581 Rhodanese-like domain 290 383 3.5E-13 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS11645 6b39d0b4dba8ee848e4bcb99105d5a13 392 SMART SM00450 290 387 2.4E-23 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS11645 6b39d0b4dba8ee848e4bcb99105d5a13 392 Gene3D G3DSA:3.40.50.720 12 258 2.1E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS11645 6b39d0b4dba8ee848e4bcb99105d5a13 392 SUPERFAMILY SSF69572 8 357 5.23E-107 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SMD11_RS11645 6b39d0b4dba8ee848e4bcb99105d5a13 392 Gene3D G3DSA:3.40.250.10 274 387 3.9E-27 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS29755 dc88fc7eea291df4a253712ef16f50ac 228 SUPERFAMILY SSF46689 3 83 1.28E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS29755 dc88fc7eea291df4a253712ef16f50ac 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 4.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS29755 dc88fc7eea291df4a253712ef16f50ac 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 4.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS29755 dc88fc7eea291df4a253712ef16f50ac 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 4.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS29755 dc88fc7eea291df4a253712ef16f50ac 228 SUPERFAMILY SSF48498 81 203 3.95E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS29755 dc88fc7eea291df4a253712ef16f50ac 228 Gene3D G3DSA:1.10.357.10 2 192 5.1E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS08950 cc858b743bf5fe74a2ab64678b310b3c 374 SUPERFAMILY SSF54752 269 327 2.09E-21 T 06-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal SMD11_RS08950 cc858b743bf5fe74a2ab64678b310b3c 374 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 5 325 3.1E-175 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD11_RS08950 cc858b743bf5fe74a2ab64678b310b3c 374 Pfam PF00154 recA bacterial DNA recombination protein 8 269 8.7E-144 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD11_RS08950 cc858b743bf5fe74a2ab64678b310b3c 374 PRINTS PR00142 RecA protein signature 94 123 1.5E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD11_RS08950 cc858b743bf5fe74a2ab64678b310b3c 374 PRINTS PR00142 RecA protein signature 128 157 1.5E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD11_RS08950 cc858b743bf5fe74a2ab64678b310b3c 374 PRINTS PR00142 RecA protein signature 166 195 1.5E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD11_RS08950 cc858b743bf5fe74a2ab64678b310b3c 374 PRINTS PR00142 RecA protein signature 298 315 1.5E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD11_RS08950 cc858b743bf5fe74a2ab64678b310b3c 374 PRINTS PR00142 RecA protein signature 244 273 1.5E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD11_RS08950 cc858b743bf5fe74a2ab64678b310b3c 374 PRINTS PR00142 RecA protein signature 211 239 1.5E-85 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD11_RS08950 cc858b743bf5fe74a2ab64678b310b3c 374 ProSitePatterns PS00321 recA signature. 214 222 - T 06-07-2017 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 SMD11_RS08950 cc858b743bf5fe74a2ab64678b310b3c 374 SMART SM00382 58 229 4.5E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS08950 cc858b743bf5fe74a2ab64678b310b3c 374 Gene3D G3DSA:3.40.50.300 28 268 4.8E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08950 cc858b743bf5fe74a2ab64678b310b3c 374 Gene3D G3DSA:3.30.250.10 269 327 1.6E-29 T 06-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal SMD11_RS08950 cc858b743bf5fe74a2ab64678b310b3c 374 SUPERFAMILY SSF52540 5 268 4.23E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08950 cc858b743bf5fe74a2ab64678b310b3c 374 Hamap MF_00268 Protein RecA [recA]. 6 330 53.067 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SMD11_RS18655 905f8e9b1e9d7343b10b0882b4cc2cf0 338 SUPERFAMILY SSF103481 197 290 8.37E-11 T 06-07-2017 SMD11_RS18655 905f8e9b1e9d7343b10b0882b4cc2cf0 338 TIGRFAM TIGR00688 rarD: protein RarD 13 263 1.2E-63 T 06-07-2017 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 SMD11_RS18655 905f8e9b1e9d7343b10b0882b4cc2cf0 338 Pfam PF00892 EamA-like transporter family 12 148 1.0E-9 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS18655 905f8e9b1e9d7343b10b0882b4cc2cf0 338 SUPERFAMILY SSF103481 50 150 2.62E-11 T 06-07-2017 SMD11_RS24505 2c637402c9454de0ce3536176cac9be8 489 Pfam PF02875 Mur ligase family, glutamate ligase domain 339 406 1.5E-6 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS24505 2c637402c9454de0ce3536176cac9be8 489 SUPERFAMILY SSF53244 338 481 2.7E-36 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS24505 2c637402c9454de0ce3536176cac9be8 489 Gene3D G3DSA:3.40.50.720 15 106 3.0E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS24505 2c637402c9454de0ce3536176cac9be8 489 Gene3D G3DSA:3.90.190.20 338 478 2.3E-44 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS24505 2c637402c9454de0ce3536176cac9be8 489 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 18 481 33.652 T 06-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS24505 2c637402c9454de0ce3536176cac9be8 489 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 125 148 - T 06-07-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 SMD11_RS24505 2c637402c9454de0ce3536176cac9be8 489 SUPERFAMILY SSF53623 121 334 6.02E-47 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS24505 2c637402c9454de0ce3536176cac9be8 489 SUPERFAMILY SSF51984 15 108 1.09E-16 T 06-07-2017 SMD11_RS24505 2c637402c9454de0ce3536176cac9be8 489 Pfam PF08245 Mur ligase middle domain 127 317 1.1E-26 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS24505 2c637402c9454de0ce3536176cac9be8 489 Gene3D G3DSA:3.40.1190.10 108 335 4.2E-66 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS24505 2c637402c9454de0ce3536176cac9be8 489 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 19 479 9.9E-115 T 06-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS24490 6d68f52f906e329645cc0a361840c48d 562 Gene3D G3DSA:3.90.190.20 393 540 1.5E-49 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS24490 6d68f52f906e329645cc0a361840c48d 562 SUPERFAMILY SSF53623 157 388 2.98E-68 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS24490 6d68f52f906e329645cc0a361840c48d 562 Gene3D G3DSA:3.40.1390.10 73 156 8.9E-22 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMD11_RS24490 6d68f52f906e329645cc0a361840c48d 562 SUPERFAMILY SSF63418 62 155 6.41E-21 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMD11_RS24490 6d68f52f906e329645cc0a361840c48d 562 Pfam PF08245 Mur ligase middle domain 166 368 2.8E-51 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS24490 6d68f52f906e329645cc0a361840c48d 562 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 76 546 2.0E-143 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 SMD11_RS24490 6d68f52f906e329645cc0a361840c48d 562 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 59 546 33.252 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 SMD11_RS24490 6d68f52f906e329645cc0a361840c48d 562 Pfam PF02875 Mur ligase family, glutamate ligase domain 389 473 1.8E-20 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS24490 6d68f52f906e329645cc0a361840c48d 562 Gene3D G3DSA:3.40.1190.10 159 392 1.1E-76 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS24490 6d68f52f906e329645cc0a361840c48d 562 SUPERFAMILY SSF53244 389 547 7.33E-44 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS24490 6d68f52f906e329645cc0a361840c48d 562 Pfam PF01225 Mur ligase family, catalytic domain 78 152 1.5E-12 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMD11_RS15025 5d41daa0fd6642c180cc533812f954c2 157 SUPERFAMILY SSF55874 46 139 2.45E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS15025 5d41daa0fd6642c180cc533812f954c2 157 Pfam PF13581 Histidine kinase-like ATPase domain 26 133 2.1E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS06430 e34b93df386e62f0901ffe5fb71d5aec 159 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 15 133 1.3E-15 T 06-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain SMD11_RS06430 e34b93df386e62f0901ffe5fb71d5aec 159 Gene3D G3DSA:3.30.530.20 14 131 1.6E-15 T 06-07-2017 IPR023393 START-like domain SMD11_RS06430 e34b93df386e62f0901ffe5fb71d5aec 159 SUPERFAMILY SSF55961 1 141 3.0E-18 T 06-07-2017 SMD11_RS05060 5e7a01fe0ec55a8262814a73a21186c7 905 Pfam PF00583 Acetyltransferase (GNAT) family 80 160 5.1E-11 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS05060 5e7a01fe0ec55a8262814a73a21186c7 905 SUPERFAMILY SSF52210 323 484 3.53E-36 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS05060 5e7a01fe0ec55a8262814a73a21186c7 905 SUPERFAMILY SSF51735 196 328 2.7E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05060 5e7a01fe0ec55a8262814a73a21186c7 905 Gene3D G3DSA:3.40.50.720 195 321 9.5E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05060 5e7a01fe0ec55a8262814a73a21186c7 905 SUPERFAMILY SSF52210 488 646 3.4E-24 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS05060 5e7a01fe0ec55a8262814a73a21186c7 905 SUPERFAMILY SSF55729 19 167 4.01E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS05060 5e7a01fe0ec55a8262814a73a21186c7 905 Gene3D G3DSA:3.40.50.261 322 480 3.7E-28 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS05060 5e7a01fe0ec55a8262814a73a21186c7 905 Pfam PF13549 ATP-grasp domain 677 891 7.4E-56 T 06-07-2017 SMD11_RS05060 5e7a01fe0ec55a8262814a73a21186c7 905 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 345 482 5.3E-43 T 06-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain SMD11_RS05060 5e7a01fe0ec55a8262814a73a21186c7 905 SMART SM00881 203 298 1.7E-28 T 06-07-2017 IPR003781 CoA-binding GO:0048037 SMD11_RS05060 5e7a01fe0ec55a8262814a73a21186c7 905 Pfam PF13380 CoA binding domain 207 326 3.5E-22 T 06-07-2017 IPR003781 CoA-binding GO:0048037 SMD11_RS05060 5e7a01fe0ec55a8262814a73a21186c7 905 Gene3D G3DSA:3.40.50.261 481 635 3.3E-9 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS05060 5e7a01fe0ec55a8262814a73a21186c7 905 SUPERFAMILY SSF56059 682 892 1.24E-27 T 06-07-2017 SMD11_RS05060 5e7a01fe0ec55a8262814a73a21186c7 905 Gene3D G3DSA:3.40.630.30 21 161 4.0E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 Hamap MF_00054_B Elongation factor G [fusA]. 7 704 110.19 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 Pfam PF03764 Elongation factor G, domain IV 492 611 1.9E-49 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 Pfam PF00009 Elongation factor Tu GTP binding domain 10 294 1.3E-65 T 06-07-2017 SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 SMART SM00889 493 611 2.2E-74 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 Gene3D G3DSA:3.30.230.10 497 610 2.2E-49 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 SMART SM00838 613 700 2.8E-57 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 Gene3D G3DSA:3.40.50.300 7 299 1.3E-103 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 Pfam PF14492 Elongation Factor G, domain II 417 491 5.9E-34 T 06-07-2017 IPR009022 Elongation factor G, III-V domain SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 Pfam PF03144 Elongation factor Tu domain 2 337 404 2.9E-15 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 SUPERFAMILY SSF52540 7 294 4.07E-103 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 Pfam PF00679 Elongation factor G C-terminus 614 699 1.3E-29 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 SUPERFAMILY SSF54211 492 612 2.25E-42 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 Gene3D G3DSA:2.40.30.10 318 417 4.4E-39 T 06-07-2017 SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 TIGRFAM TIGR00484 EF-G: translation elongation factor G 5 705 0.0 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 185 1.4E-33 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 SUPERFAMILY SSF54980 616 703 4.27E-30 T 06-07-2017 IPR009022 Elongation factor G, III-V domain SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 PRINTS PR00315 GTP-binding elongation factor signature 99 110 4.1E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 PRINTS PR00315 GTP-binding elongation factor signature 135 144 4.1E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.1E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 PRINTS PR00315 GTP-binding elongation factor signature 59 67 4.1E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 PRINTS PR00315 GTP-binding elongation factor signature 83 93 4.1E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 SUPERFAMILY SSF54980 417 494 7.91E-25 T 06-07-2017 IPR009022 Elongation factor G, III-V domain SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 Gene3D G3DSA:3.30.70.870 418 493 4.1E-38 T 06-07-2017 SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 Gene3D G3DSA:3.30.70.240 611 704 1.7E-33 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain SMD11_RS18865 ab09d853b2fdf33d9582f9d6db592248 707 SUPERFAMILY SSF50447 277 417 6.36E-37 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS07740 cef40949da0dc6f52c0c32752d05844d 361 Gene3D G3DSA:3.40.47.10 220 343 6.4E-20 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07740 cef40949da0dc6f52c0c32752d05844d 361 SUPERFAMILY SSF53901 234 341 1.49E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07740 cef40949da0dc6f52c0c32752d05844d 361 SUPERFAMILY SSF53901 169 187 1.49E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07740 cef40949da0dc6f52c0c32752d05844d 361 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 258 342 1.9E-8 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS07740 cef40949da0dc6f52c0c32752d05844d 361 SUPERFAMILY SSF53901 4 186 1.92E-40 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07740 cef40949da0dc6f52c0c32752d05844d 361 Gene3D G3DSA:3.40.47.10 4 187 8.6E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07740 cef40949da0dc6f52c0c32752d05844d 361 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 111 189 2.2E-15 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS10225 22a3d539bb70df2165e47bca6c26b493 348 SMART SM00420 5 61 8.8E-4 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS10225 22a3d539bb70df2165e47bca6c26b493 348 Gene3D G3DSA:1.10.10.10 2 61 7.9E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS10225 22a3d539bb70df2165e47bca6c26b493 348 Pfam PF13280 WYL domain 141 310 2.6E-31 T 06-07-2017 IPR026881 WYL domain SMD11_RS10225 22a3d539bb70df2165e47bca6c26b493 348 SUPERFAMILY SSF46785 3 58 1.96E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS10225 22a3d539bb70df2165e47bca6c26b493 348 Pfam PF08279 HTH domain 5 57 2.8E-18 T 06-07-2017 IPR013196 Helix-turn-helix, type 11 SMD11_RS17680 871e473435009367343dad1c82d776f6 882 SUPERFAMILY SSF81923 4 157 3.04E-30 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS17680 871e473435009367343dad1c82d776f6 882 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 5 866 0.0 T 06-07-2017 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 SMD11_RS17680 871e473435009367343dad1c82d776f6 882 Gene3D G3DSA:3.40.50.300 560 783 1.8E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17680 871e473435009367343dad1c82d776f6 882 SUPERFAMILY SSF52540 158 553 2.66E-91 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17680 871e473435009367343dad1c82d776f6 882 Gene3D G3DSA:3.40.50.300 160 343 1.0E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17680 871e473435009367343dad1c82d776f6 882 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 67 2.4E-4 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS17680 871e473435009367343dad1c82d776f6 882 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 4.1E-11 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS17680 871e473435009367343dad1c82d776f6 882 SMART SM00382 605 774 2.4E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS17680 871e473435009367343dad1c82d776f6 882 SMART SM00382 199 345 2.7E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS17680 871e473435009367343dad1c82d776f6 882 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 654 672 6.0E-41 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 SMD11_RS17680 871e473435009367343dad1c82d776f6 882 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 683 701 6.0E-41 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 SMD11_RS17680 871e473435009367343dad1c82d776f6 882 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 716 730 6.0E-41 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 SMD11_RS17680 871e473435009367343dad1c82d776f6 882 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 609 627 6.0E-41 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 SMD11_RS17680 871e473435009367343dad1c82d776f6 882 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 338 8.7E-12 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS17680 871e473435009367343dad1c82d776f6 882 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 772 862 8.0E-20 T 06-07-2017 IPR019489 Clp ATPase, C-terminal SMD11_RS17680 871e473435009367343dad1c82d776f6 882 SMART SM01086 772 874 1.0E-29 T 06-07-2017 IPR019489 Clp ATPase, C-terminal SMD11_RS17680 871e473435009367343dad1c82d776f6 882 Pfam PF07724 AAA domain (Cdc48 subfamily) 604 765 9.5E-53 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS17680 871e473435009367343dad1c82d776f6 882 Gene3D G3DSA:1.10.1780.10 4 149 1.2E-32 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS17680 871e473435009367343dad1c82d776f6 882 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 639 657 - T 06-07-2017 IPR028299 ClpA/B, conserved site 2 SMD11_RS17680 871e473435009367343dad1c82d776f6 882 SUPERFAMILY SSF52540 554 863 8.49E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17680 871e473435009367343dad1c82d776f6 882 Gene3D G3DSA:1.10.8.60 784 867 1.8E-23 T 06-07-2017 SMD11_RS17680 871e473435009367343dad1c82d776f6 882 Gene3D G3DSA:1.10.8.60 345 428 5.2E-35 T 06-07-2017 SMD11_RS17680 871e473435009367343dad1c82d776f6 882 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 SMD11_RS09190 9704193ee30d0824428da8787571705d 491 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 360 370 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site SMD11_RS09190 9704193ee30d0824428da8787571705d 491 Gene3D G3DSA:3.40.50.200 28 101 2.5E-75 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS09190 9704193ee30d0824428da8787571705d 491 Gene3D G3DSA:3.40.50.200 201 417 2.5E-75 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS09190 9704193ee30d0824428da8787571705d 491 SUPERFAMILY SSF52743 194 418 1.7E-73 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS09190 9704193ee30d0824428da8787571705d 491 SUPERFAMILY SSF52743 35 81 1.7E-73 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS09190 9704193ee30d0824428da8787571705d 491 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 202 212 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site SMD11_RS09190 9704193ee30d0824428da8787571705d 491 PRINTS PR00723 Subtilisin serine protease family (S8) signature 58 77 1.9E-16 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS09190 9704193ee30d0824428da8787571705d 491 PRINTS PR00723 Subtilisin serine protease family (S8) signature 359 375 1.9E-16 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS09190 9704193ee30d0824428da8787571705d 491 PRINTS PR00723 Subtilisin serine protease family (S8) signature 198 211 1.9E-16 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS09190 9704193ee30d0824428da8787571705d 491 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 63 74 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site SMD11_RS09190 9704193ee30d0824428da8787571705d 491 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 192 486 1.4E-89 T 06-07-2017 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 SMD11_RS09190 9704193ee30d0824428da8787571705d 491 Pfam PF00082 Subtilase family 60 409 2.3E-47 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS07035 f4b0e460971b2d986f0a88b1246cb002 959 Gene3D G3DSA:3.40.50.300 722 946 3.9E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07035 f4b0e460971b2d986f0a88b1246cb002 959 SMART SM00382 749 932 3.7E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS07035 f4b0e460971b2d986f0a88b1246cb002 959 Pfam PF00664 ABC transporter transmembrane region 418 678 8.8E-18 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS07035 f4b0e460971b2d986f0a88b1246cb002 959 ProSitePatterns PS00211 ABC transporters family signature. 860 874 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS07035 f4b0e460971b2d986f0a88b1246cb002 959 TIGRFAM TIGR03797 NHLM_micro_ABC2: NHLM bacteriocin system ABC transporter, ATP-binding protein 275 958 5.0E-256 T 06-07-2017 IPR022515 NHPM bacteriocin system ABC transporter, ATP-binding protein SMD11_RS07035 f4b0e460971b2d986f0a88b1246cb002 959 Pfam PF00005 ABC transporter 740 888 5.9E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS07035 f4b0e460971b2d986f0a88b1246cb002 959 SUPERFAMILY SSF90123 397 690 1.83E-35 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS07035 f4b0e460971b2d986f0a88b1246cb002 959 Gene3D G3DSA:1.20.1560.10 398 703 1.5E-30 T 06-07-2017 SMD11_RS07035 f4b0e460971b2d986f0a88b1246cb002 959 SUPERFAMILY SSF52540 718 957 2.46E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10985 f813f2b6d1b4160b8cfe42bafe14634e 950 Gene3D G3DSA:3.10.170.10 316 460 1.7E-36 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS10985 f813f2b6d1b4160b8cfe42bafe14634e 950 Gene3D G3DSA:2.120.10.60 685 730 1.1E-5 T 06-07-2017 SMD11_RS10985 f813f2b6d1b4160b8cfe42bafe14634e 950 Gene3D G3DSA:2.120.10.60 774 940 1.1E-5 T 06-07-2017 SMD11_RS10985 f813f2b6d1b4160b8cfe42bafe14634e 950 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 295 456 2.6E-37 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS10985 f813f2b6d1b4160b8cfe42bafe14634e 950 SUPERFAMILY SSF55486 293 613 8.06E-62 T 06-07-2017 SMD11_RS10985 f813f2b6d1b4160b8cfe42bafe14634e 950 Gene3D G3DSA:1.10.390.10 461 616 3.7E-25 T 06-07-2017 SMD11_RS10985 f813f2b6d1b4160b8cfe42bafe14634e 950 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 468 479 1.2E-17 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS10985 f813f2b6d1b4160b8cfe42bafe14634e 950 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 412 432 1.2E-17 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS10985 f813f2b6d1b4160b8cfe42bafe14634e 950 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 447 463 1.2E-17 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS10985 f813f2b6d1b4160b8cfe42bafe14634e 950 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 539 555 1.2E-17 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS10985 f813f2b6d1b4160b8cfe42bafe14634e 950 SUPERFAMILY SSF69304 648 857 1.2E-6 T 06-07-2017 SMD11_RS10985 f813f2b6d1b4160b8cfe42bafe14634e 950 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 459 613 4.0E-29 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 SMD11_RS17055 65038b5e523fad2b04c88332356276dc 175 Gene3D G3DSA:2.60.200.20 81 174 4.7E-27 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS17055 65038b5e523fad2b04c88332356276dc 175 SMART SM00240 101 152 7.6E-13 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS17055 65038b5e523fad2b04c88332356276dc 175 Pfam PF00498 FHA domain 103 167 1.5E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS17055 65038b5e523fad2b04c88332356276dc 175 SUPERFAMILY SSF49879 50 174 8.99E-29 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Pfam PF00501 AMP-binding enzyme 2965 3346 6.6E-85 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Pfam PF00501 AMP-binding enzyme 470 867 8.5E-89 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Pfam PF00501 AMP-binding enzyme 1924 2318 4.7E-97 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SUPERFAMILY SSF47336 3445 3516 5.76E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SUPERFAMILY SSF52777 1482 1666 6.56E-41 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SUPERFAMILY SSF52777 2509 2679 4.0E-50 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SUPERFAMILY SSF47336 964 1034 2.36E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SUPERFAMILY SSF52777 196 432 1.01E-36 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SUPERFAMILY SSF53474 3519 3781 4.7E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 ProSitePatterns PS00012 Phosphopantetheine attachment site. 995 1010 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2060 2071 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SUPERFAMILY SSF52777 1223 1479 1.56E-26 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Pfam PF00550 Phosphopantetheine attachment site 3453 3516 1.2E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Pfam PF00550 Phosphopantetheine attachment site 973 1033 1.3E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Pfam PF00550 Phosphopantetheine attachment site 2424 2487 8.4E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:1.10.1200.10 2428 2488 1.9E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:1.10.1200.10 3456 3520 2.0E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:1.10.1200.10 975 1036 1.7E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SUPERFAMILY SSF47336 2415 2487 3.27E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Pfam PF00668 Condensation domain 1483 1766 1.2E-51 T 06-07-2017 IPR001242 Condensation domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Pfam PF00668 Condensation domain 12 306 6.6E-31 T 06-07-2017 IPR001242 Condensation domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Pfam PF00668 Condensation domain 1158 1332 2.9E-19 T 06-07-2017 IPR001242 Condensation domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Pfam PF00668 Condensation domain 2506 2794 8.2E-64 T 06-07-2017 IPR001242 Condensation domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1945 2342 2.3E-132 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2986 3370 2.4E-119 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 493 890 3.8E-122 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SUPERFAMILY SSF56801 2924 3464 5.89E-143 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SMART SM00824 Thioesterase 3541 3781 0.0018 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SMART SM00823 Phosphopantetheine attachment site 3451 3520 1.2E-5 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SMART SM00823 Phosphopantetheine attachment site 2422 2491 7.1E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SMART SM00823 Phosphopantetheine attachment site 971 1039 1.3E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1347 1484 2.5E-23 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3475 3490 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 ProSitePatterns PS00455 Putative AMP-binding domain signature. 613 624 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Pfam PF13193 AMP-binding enzyme C-terminal domain 875 946 1.2E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Pfam PF13193 AMP-binding enzyme C-terminal domain 3354 3426 3.6E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Pfam PF13193 AMP-binding enzyme C-terminal domain 2326 2398 3.1E-12 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SUPERFAMILY SSF52777 1653 1897 7.23E-54 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Pfam PF13745 HxxPF-repeated domain 2816 2910 1.5E-26 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3094 3105 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SUPERFAMILY SSF56801 1911 2435 7.98E-153 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SUPERFAMILY SSF52777 14 190 5.23E-24 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SUPERFAMILY SSF56801 463 984 1.18E-139 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:2.30.38.10 2229 2308 1.0E-25 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:2.30.38.10 3258 3335 3.5E-26 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:2.30.38.10 779 856 7.2E-25 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SUPERFAMILY SSF52777 1054 1205 6.34E-22 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:3.40.50.980 3116 3257 6.4E-38 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:3.40.50.980 638 778 4.0E-34 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:3.30.300.30 863 974 1.1E-34 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:3.30.300.30 2313 2427 2.1E-36 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:3.30.300.30 3341 3455 9.9E-33 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Pfam PF00975 Thioesterase domain 3539 3771 1.8E-25 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 SUPERFAMILY SSF52777 2681 2953 6.23E-62 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2446 2461 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:3.40.50.1820 3526 3642 1.4E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:3.40.50.1820 3715 3782 1.4E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:3.40.50.980 2068 2224 2.5E-44 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:3.40.50.980 2959 3115 9.7E-37 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:3.40.50.980 466 635 9.3E-40 T 06-07-2017 SMD11_RS01175 cd1f41923312111cf83c0eb8f717c821 3785 Gene3D G3DSA:3.40.50.980 1920 2067 4.7E-44 T 06-07-2017 SMD11_RS06940 3dd3c732d67a1154f19e46c260ff2391 455 SUPERFAMILY SSF51556 61 375 2.61E-93 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS06940 3dd3c732d67a1154f19e46c260ff2391 455 Pfam PF01979 Amidohydrolase family 58 390 1.3E-60 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 SMD11_RS06940 3dd3c732d67a1154f19e46c260ff2391 455 SUPERFAMILY SSF51338 3 75 1.3E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS06940 3dd3c732d67a1154f19e46c260ff2391 455 Gene3D G3DSA:2.30.40.10 384 420 6.1E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS06940 3dd3c732d67a1154f19e46c260ff2391 455 Gene3D G3DSA:2.30.40.10 3 63 6.1E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS06940 3dd3c732d67a1154f19e46c260ff2391 455 Gene3D G3DSA:3.20.20.140 64 383 1.5E-104 T 06-07-2017 SMD11_RS06940 3dd3c732d67a1154f19e46c260ff2391 455 SUPERFAMILY SSF51338 336 453 1.0E-27 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS33465 4811cd25e2bef8f7db9062abe856ec1c 353 Gene3D G3DSA:3.90.470.20 139 232 3.8E-11 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS33465 4811cd25e2bef8f7db9062abe856ec1c 353 SUPERFAMILY SSF56214 228 335 7.15E-16 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS33465 4811cd25e2bef8f7db9062abe856ec1c 353 SUPERFAMILY SSF56214 138 223 4.97E-8 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS33465 4811cd25e2bef8f7db9062abe856ec1c 353 Gene3D G3DSA:3.90.470.20 233 316 2.4E-13 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS33465 4811cd25e2bef8f7db9062abe856ec1c 353 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 228 294 3.3E-9 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS14760 3f98c7879eb29bbcda4613a83d6b3376 307 Pfam PF00633 Helix-hairpin-helix motif 108 136 4.2E-6 T 06-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 SMD11_RS14760 3f98c7879eb29bbcda4613a83d6b3376 307 ProSitePatterns PS01155 Endonuclease III family signature. 110 139 - T 06-07-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 SMD11_RS14760 3f98c7879eb29bbcda4613a83d6b3376 307 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 43 171 3.4E-11 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMD11_RS14760 3f98c7879eb29bbcda4613a83d6b3376 307 SMART SM00478 47 199 5.9E-35 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMD11_RS14760 3f98c7879eb29bbcda4613a83d6b3376 307 Gene3D G3DSA:1.10.340.30 30 130 3.0E-34 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD11_RS14760 3f98c7879eb29bbcda4613a83d6b3376 307 Gene3D G3DSA:1.10.1670.10 131 227 8.8E-35 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SMD11_RS14760 3f98c7879eb29bbcda4613a83d6b3376 307 SMART SM00525 200 220 0.0011 T 06-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 SMD11_RS14760 3f98c7879eb29bbcda4613a83d6b3376 307 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 201 217 3.5E-4 T 06-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 SMD11_RS14760 3f98c7879eb29bbcda4613a83d6b3376 307 SUPERFAMILY SSF48150 14 227 1.73E-63 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD11_RS08100 a7899f5a26d53e2bbe8a8b8fb4514a34 139 SUPERFAMILY SSF54427 14 135 3.0E-24 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS08100 a7899f5a26d53e2bbe8a8b8fb4514a34 139 Gene3D G3DSA:3.10.450.50 14 135 5.4E-32 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS08100 a7899f5a26d53e2bbe8a8b8fb4514a34 139 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 16 136 1.8E-16 T 06-07-2017 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 SMD11_RS08100 a7899f5a26d53e2bbe8a8b8fb4514a34 139 Pfam PF14534 Domain of unknown function (DUF4440) 20 129 4.0E-12 T 06-07-2017 IPR027843 Domain of unknown function DUF4440 SMD11_RS05800 c6af025aa4ecce45634e195d8c88dbcb 260 SUPERFAMILY SSF48452 103 253 1.26E-21 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS05800 c6af025aa4ecce45634e195d8c88dbcb 260 Pfam PF03704 Bacterial transcriptional activator domain 107 223 8.0E-24 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS05800 c6af025aa4ecce45634e195d8c88dbcb 260 Pfam PF00486 Transcriptional regulatory protein, C terminal 21 90 6.0E-7 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS05800 c6af025aa4ecce45634e195d8c88dbcb 260 SMART SM00862 18 100 2.4E-10 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS05800 c6af025aa4ecce45634e195d8c88dbcb 260 Gene3D G3DSA:1.10.10.10 16 86 3.4E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05800 c6af025aa4ecce45634e195d8c88dbcb 260 SUPERFAMILY SSF46894 5 86 2.24E-12 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS05800 c6af025aa4ecce45634e195d8c88dbcb 260 SMART SM01043 107 251 9.5E-22 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS20440 ae0eff68593595a353a4d9f638d65405 76 Pfam PF14117 Domain of unknown function (DUF4287) 9 67 7.4E-24 T 06-07-2017 IPR025629 Protein of unknown function DUF4287 SMD11_RS09930 2fe39cfc230b0edf16417b21055d784e 211 SUPERFAMILY SSF101874 35 207 9.68E-58 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS09930 2fe39cfc230b0edf16417b21055d784e 211 SMART SM00867 36 205 1.0E-69 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS09930 2fe39cfc230b0edf16417b21055d784e 211 Pfam PF04264 YceI-like domain 37 203 4.5E-45 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS09930 2fe39cfc230b0edf16417b21055d784e 211 Gene3D G3DSA:2.40.128.110 35 207 8.6E-62 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS07175 3bf5a36096ba7a95a642c2a986ed5eda 391 Pfam PF03631 Virulence factor BrkB 45 298 4.2E-47 T 06-07-2017 IPR017039 Virulence factor BrkB SMD11_RS09880 4c4cfd26c6e8e4b271569babd18dec73 140 Gene3D G3DSA:3.30.450.30 6 126 1.4E-25 T 06-07-2017 SMD11_RS09880 4c4cfd26c6e8e4b271569babd18dec73 140 SUPERFAMILY SSF103196 4 128 3.92E-32 T 06-07-2017 SMD11_RS09880 4c4cfd26c6e8e4b271569babd18dec73 140 Pfam PF03259 Roadblock/LC7 domain 12 102 1.6E-25 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS09880 4c4cfd26c6e8e4b271569babd18dec73 140 SMART SM00960 12 102 3.3E-33 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS09975 10ba24e899131b9a58bca3650b15691c 193 Pfam PF01066 CDP-alcohol phosphatidyltransferase 28 95 4.4E-6 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD11_RS03635 091b3a58060ad5ece7ba154a1104ce7b 280 SUPERFAMILY SSF53649 30 263 9.16E-9 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMD11_RS03635 091b3a58060ad5ece7ba154a1104ce7b 280 Gene3D G3DSA:3.40.720.10 33 121 1.7E-4 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMD11_RS03635 091b3a58060ad5ece7ba154a1104ce7b 280 Pfam PF04185 Phosphoesterase family 54 261 1.2E-30 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 SMD11_RS09360 10f7506455dc4aec94d28426e2f730c8 391 SUPERFAMILY SSF52540 19 257 7.68E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09360 10f7506455dc4aec94d28426e2f730c8 391 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS09360 10f7506455dc4aec94d28426e2f730c8 391 Pfam PF08402 TOBE domain 293 372 1.9E-13 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SMD11_RS09360 10f7506455dc4aec94d28426e2f730c8 391 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 49 370 7.5E-109 T 06-07-2017 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 SMD11_RS09360 10f7506455dc4aec94d28426e2f730c8 391 SUPERFAMILY SSF50331 250 372 3.16E-15 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal SMD11_RS09360 10f7506455dc4aec94d28426e2f730c8 391 Gene3D G3DSA:3.40.50.300 10 248 1.0E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09360 10f7506455dc4aec94d28426e2f730c8 391 SMART SM00382 43 271 1.1E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS09360 10f7506455dc4aec94d28426e2f730c8 391 Pfam PF00005 ABC transporter 36 174 9.2E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 Pfam PF08238 Sel1 repeat 509 538 0.035 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 Pfam PF08238 Sel1 repeat 474 506 0.0021 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 Pfam PF08238 Sel1 repeat 554 570 20.0 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 Pfam PF08238 Sel1 repeat 284 313 16.0 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 Pfam PF08238 Sel1 repeat 174 186 6.1 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 Pfam PF08238 Sel1 repeat 411 441 1.9E-4 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 Pfam PF08238 Sel1 repeat 379 409 12.0 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 Pfam PF08238 Sel1 repeat 236 249 0.34 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00028 60 93 200.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00028 571 604 130.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00028 282 315 420.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00028 410 443 29.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00028 507 540 150.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00028 346 379 47.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 Gene3D G3DSA:1.25.40.10 52 196 3.1E-25 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 Gene3D G3DSA:1.25.40.10 232 407 6.5E-40 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SUPERFAMILY SSF81901 235 352 1.7E-18 T 06-07-2017 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SUPERFAMILY SSF81901 319 481 1.15E-25 T 06-07-2017 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 Pfam PF13374 Tetratricopeptide repeat 315 342 0.015 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00671 314 345 79.0 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00671 442 473 210.0 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00671 346 377 14.0 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00671 124 155 0.084 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00671 282 313 5.9 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00671 507 538 1.1 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00671 474 506 9.7 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00671 60 91 130.0 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00671 378 409 3.9 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00671 410 441 0.0012 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00671 156 186 3.7 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00671 539 570 11.0 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00671 92 123 180.0 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SMART SM00671 250 281 240.0 T 06-07-2017 IPR006597 Sel1-like repeat SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 Pfam PF13432 Tetratricopeptide repeat 350 373 0.013 T 06-07-2017 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 Pfam PF13432 Tetratricopeptide repeat 65 124 0.015 T 06-07-2017 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SUPERFAMILY SSF81901 60 198 5.23E-17 T 06-07-2017 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 Gene3D G3DSA:1.25.40.10 408 504 7.0E-21 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 Gene3D G3DSA:1.25.40.10 505 605 3.3E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS11480 81e10c5274e4e9ccca23d452f0360075 622 SUPERFAMILY SSF81901 492 604 1.7E-20 T 06-07-2017 SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 Pfam PF03461 TRCF domain 1041 1122 3.5E-24 T 06-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 Gene3D G3DSA:3.40.50.300 833 987 1.7E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 SMART SM01058 506 607 1.9E-46 T 06-07-2017 IPR003711 CarD-like/TRCF domain SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 SMART SM00490 857 941 4.4E-14 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 SUPERFAMILY SSF52540 396 488 5.84E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 Gene3D G3DSA:3.30.2060.10 149 224 2.4E-14 T 06-07-2017 SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 167 1113 0.0 T 06-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 44 1133 28.615 T 06-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 Pfam PF00271 Helicase conserved C-terminal domain 841 940 1.1E-13 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 Gene3D G3DSA:3.40.50.300 619 817 2.3E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 SUPERFAMILY SSF141259 500 579 9.94E-18 T 06-07-2017 IPR003711 CarD-like/TRCF domain SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 SMART SM00982 1040 1138 1.4E-36 T 06-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 SUPERFAMILY SSF143517 1027 1148 2.62E-32 T 06-07-2017 SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 Pfam PF00270 DEAD/DEAH box helicase 637 798 8.8E-17 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 SUPERFAMILY SSF52540 556 814 9.83E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 SMART SM00487 631 821 1.3E-31 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 SUPERFAMILY SSF52540 17 367 5.84E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 Pfam PF02559 CarD-like/TRCF domain 507 606 1.9E-30 T 06-07-2017 IPR003711 CarD-like/TRCF domain SMD11_RS20230 b22ac321d97e65aecfd0e8fd8093a65d 1185 SUPERFAMILY SSF52540 813 1021 3.55E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08215 2536b59fb8e54b64c818e0751262ffc2 311 Pfam PF13469 Sulfotransferase family 100 151 8.0E-7 T 06-07-2017 SMD11_RS08215 2536b59fb8e54b64c818e0751262ffc2 311 Gene3D G3DSA:3.40.50.300 96 160 4.0E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08215 2536b59fb8e54b64c818e0751262ffc2 311 Gene3D G3DSA:3.40.50.300 194 272 4.0E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08215 2536b59fb8e54b64c818e0751262ffc2 311 SUPERFAMILY SSF52540 73 157 3.49E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08215 2536b59fb8e54b64c818e0751262ffc2 311 SUPERFAMILY SSF52540 190 269 3.49E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13220 b5e065fab18df9d3d790451e3eaf3254 520 SUPERFAMILY SSF52335 10 198 4.71E-63 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain SMD11_RS13220 b5e065fab18df9d3d790451e3eaf3254 520 SMART SM00851 22 136 8.1E-47 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain SMD11_RS13220 b5e065fab18df9d3d790451e3eaf3254 520 Pfam PF01808 AICARFT/IMPCHase bienzyme 141 453 1.4E-114 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS13220 b5e065fab18df9d3d790451e3eaf3254 520 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 11 520 4.3E-176 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS13220 b5e065fab18df9d3d790451e3eaf3254 520 Gene3D G3DSA:3.40.140.20 246 363 1.8E-45 T 06-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS13220 b5e065fab18df9d3d790451e3eaf3254 520 PIRSF PIRSF000414 4 520 1.8E-197 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS13220 b5e065fab18df9d3d790451e3eaf3254 520 Gene3D G3DSA:3.40.50.1380 8 191 1.0E-75 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain SMD11_RS13220 b5e065fab18df9d3d790451e3eaf3254 520 SUPERFAMILY SSF53927 216 520 3.51E-117 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 SMD11_RS13220 b5e065fab18df9d3d790451e3eaf3254 520 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 10 520 41.973 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS13220 b5e065fab18df9d3d790451e3eaf3254 520 Gene3D G3DSA:3.40.140.20 367 510 6.2E-52 T 06-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS13220 b5e065fab18df9d3d790451e3eaf3254 520 Pfam PF02142 MGS-like domain 22 135 2.3E-24 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain SMD11_RS13220 b5e065fab18df9d3d790451e3eaf3254 520 SMART SM00798 141 454 2.0E-182 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS05315 1a3a1c535adf5823774d26de4cd778f7 340 TIGRFAM TIGR03470 HpnH: hopanoid biosynthesis associated radical SAM protein HpnH 1 318 2.6E-162 T 06-07-2017 IPR017833 Hopanoid biosynthesis associated radical SAM protein HpnH SMD11_RS05315 1a3a1c535adf5823774d26de4cd778f7 340 Pfam PF11946 Domain of unknown function (DUF3463) 196 328 3.7E-56 T 06-07-2017 IPR022563 Domain of unknown function DUF3463 SMD11_RS05315 1a3a1c535adf5823774d26de4cd778f7 340 Gene3D G3DSA:3.20.20.70 19 310 8.3E-41 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS05315 1a3a1c535adf5823774d26de4cd778f7 340 Pfam PF13394 4Fe-4S single cluster domain 37 116 1.8E-5 T 06-07-2017 SMD11_RS05315 1a3a1c535adf5823774d26de4cd778f7 340 Pfam PF04055 Radical SAM superfamily 34 187 7.5E-17 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS05315 1a3a1c535adf5823774d26de4cd778f7 340 SUPERFAMILY SSF102114 23 308 2.49E-47 T 06-07-2017 SMD11_RS11965 4c6059454228d80d391ba76ebad9eda1 595 Gene3D G3DSA:3.40.190.10 251 365 1.2E-12 T 06-07-2017 SMD11_RS11965 4c6059454228d80d391ba76ebad9eda1 595 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 117 509 1.6E-58 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain SMD11_RS11965 4c6059454228d80d391ba76ebad9eda1 595 Gene3D G3DSA:3.90.76.10 82 250 8.3E-23 T 06-07-2017 SMD11_RS11965 4c6059454228d80d391ba76ebad9eda1 595 Gene3D G3DSA:3.10.105.10 366 564 1.5E-35 T 06-07-2017 SMD11_RS11965 4c6059454228d80d391ba76ebad9eda1 595 SUPERFAMILY SSF53850 69 594 2.04E-79 T 06-07-2017 SMD11_RS11965 4c6059454228d80d391ba76ebad9eda1 595 PIRSF PIRSF002741 45 594 5.3E-54 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 Gene3D G3DSA:1.10.730.10 763 897 4.4E-33 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 SUPERFAMILY SSF50677 295 522 3.14E-43 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 68 78 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 PRINTS PR00985 Leucyl-tRNA synthetase signature 225 241 1.2E-52 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 PRINTS PR00985 Leucyl-tRNA synthetase signature 651 673 1.2E-52 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 169 1.2E-52 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 PRINTS PR00985 Leucyl-tRNA synthetase signature 287 306 1.2E-52 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 PRINTS PR00985 Leucyl-tRNA synthetase signature 684 694 1.2E-52 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 PRINTS PR00985 Leucyl-tRNA synthetase signature 603 621 1.2E-52 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 PRINTS PR00985 Leucyl-tRNA synthetase signature 258 271 1.2E-52 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 Gene3D G3DSA:3.90.740.10 296 527 5.5E-49 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 Pfam PF08264 Anticodon-binding domain of tRNA 811 923 5.0E-15 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 SUPERFAMILY SSF47323 778 960 6.54E-28 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 SUPERFAMILY SSF52374 23 172 7.43E-112 T 06-07-2017 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 SUPERFAMILY SSF52374 519 782 7.43E-112 T 06-07-2017 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 SUPERFAMILY SSF52374 220 298 7.43E-112 T 06-07-2017 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 371 506 6.7E-36 T 06-07-2017 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 293 342 9.5E-18 T 06-07-2017 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 Gene3D G3DSA:3.40.50.620 733 762 1.3E-135 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 Gene3D G3DSA:3.40.50.620 22 171 1.3E-135 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 Gene3D G3DSA:3.40.50.620 528 700 1.3E-135 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 Gene3D G3DSA:3.40.50.620 219 295 1.3E-135 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 18 961 21.068 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SMD11_RS22550 4e041f518c813fa461927e29b54eb3c3 962 Pfam PF09334 tRNA synthetases class I (M) 65 168 2.1E-13 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS03220 14ab44ccdadd833eb9e9f8df52716c33 261 Gene3D G3DSA:3.40.50.620 3 260 5.2E-85 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS03220 14ab44ccdadd833eb9e9f8df52716c33 261 SUPERFAMILY SSF52402 3 257 4.51E-70 T 06-07-2017 SMD11_RS03220 14ab44ccdadd833eb9e9f8df52716c33 261 PIRSF PIRSF000090 3 261 3.3E-82 T 06-07-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 SMD11_RS03220 14ab44ccdadd833eb9e9f8df52716c33 261 SMART SM00893 24 214 4.9E-57 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SMD11_RS03220 14ab44ccdadd833eb9e9f8df52716c33 261 Pfam PF01012 Electron transfer flavoprotein domain 25 209 1.6E-45 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF55048 3179 3239 2.88E-8 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF47336 2418 2534 2.09E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF14765 Polyketide synthase dehydratase 3419 3700 1.1E-48 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF47336 916 1036 3.4E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2136 2315 2.1E-54 T 06-07-2017 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3921 4101 1.8E-49 T 06-07-2017 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF51735 2134 2367 2.28E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:1.10.1200.10 919 993 2.2E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:1.10.1200.10 4219 4293 2.3E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:1.10.1200.10 2420 2496 2.6E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.40.366.10 723 836 1.4E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.40.366.10 1546 1672 4.2E-76 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.40.366.10 3047 3174 8.3E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.40.366.10 3239 3353 8.3E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.40.366.10 531 658 1.4E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.40.366.10 1737 1852 4.2E-76 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2451 2466 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1555 1847 8.9E-113 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3056 3349 4.2E-112 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 540 832 4.0E-117 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.40.47.10 2783 2950 1.4E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.40.47.10 1284 1449 7.5E-64 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.40.47.10 270 437 3.4E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.40.50.720 3921 4105 4.9E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.40.50.720 2136 2351 2.3E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.40.47.10 31 269 7.8E-84 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.40.47.10 1023 1283 7.8E-90 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.40.47.10 2522 2782 6.8E-94 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF52151 3240 3334 3.4E-71 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF52151 3052 3180 3.4E-71 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF08659 KR domain 2136 2313 1.4E-55 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF08659 KR domain 3921 4100 2.0E-52 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SMART SM00826 3419 3588 1.3E-66 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF55048 1677 1737 2.49E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF51735 3920 4135 3.9E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4248 4263 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1021 1271 1.0E-85 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 30 257 3.1E-72 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2520 2770 2.8E-94 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF55048 663 723 2.49E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.30.70.250 680 722 2.3E-6 T 06-07-2017 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.30.70.250 3191 3238 1.4E-5 T 06-07-2017 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Gene3D G3DSA:3.30.70.250 1694 1736 2.3E-6 T 06-07-2017 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF47336 4213 4300 3.27E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF52151 724 821 1.62E-72 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF52151 537 664 1.62E-72 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2778 2894 5.2E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 266 382 8.0E-39 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1279 1394 1.6E-42 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF00550 Phosphopantetheine attachment site 2426 2492 6.7E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF00550 Phosphopantetheine attachment site 4224 4289 1.8E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF00550 Phosphopantetheine attachment site 925 991 1.2E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF00698 Acyl transferase domain 1555 1865 6.9E-59 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF00698 Acyl transferase domain 3056 3364 6.4E-59 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF00698 Acyl transferase domain 540 847 4.8E-59 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SMART SM01294 4222 4289 7.6E-4 T 06-07-2017 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SMART SM01294 924 991 4.5E-5 T 06-07-2017 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SMART SM00823 Phosphopantetheine attachment site 4221 4293 2.5E-29 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SMART SM00823 Phosphopantetheine attachment site 923 995 5.3E-22 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SMART SM00823 Phosphopantetheine attachment site 2424 2496 7.9E-24 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF53901 1017 1393 1.12E-97 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF51735 3710 3902 2.52E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SMART SM00825 Beta-ketoacyl synthase 2522 2948 7.4E-224 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SMART SM00825 Beta-ketoacyl synthase 1023 1449 1.1E-208 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SMART SM00825 Beta-ketoacyl synthase 31 437 6.8E-181 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF53901 2516 2886 2.42E-103 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF51735 1918 2126 1.06E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF52151 1738 1832 3.92E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF52151 1552 1678 3.92E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2683 2699 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 SUPERFAMILY SSF53901 28 375 5.3E-83 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 385 499 5.4E-18 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1398 1507 2.4E-15 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08060 1246500d988da5b57b47cee7f4062eea 4386 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2897 3008 4.1E-13 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 SUPERFAMILY SSF53474 1590 1875 1.19E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 Gene3D G3DSA:3.40.50.980 1156 1309 1.5E-31 T 06-07-2017 SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 SUPERFAMILY SSF52777 190 422 2.11E-32 T 06-07-2017 SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 Gene3D G3DSA:3.40.50.1820 1799 1878 2.0E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 Gene3D G3DSA:3.40.50.1820 1598 1716 2.0E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 Gene3D G3DSA:3.30.300.30 1405 1529 6.6E-29 T 06-07-2017 SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 Pfam PF13193 AMP-binding enzyme C-terminal domain 1430 1498 1.8E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 SUPERFAMILY SSF47336 456 523 2.22E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 Pfam PF00668 Condensation domain 557 855 1.5E-32 T 06-07-2017 IPR001242 Condensation domain SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 Pfam PF00668 Condensation domain 7 293 2.5E-39 T 06-07-2017 IPR001242 Condensation domain SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 SMART SM00823 Phosphopantetheine attachment site 1525 1594 1.8E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 Pfam PF00975 Thioesterase domain 1613 1872 2.1E-33 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1029 1425 3.5E-115 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 Gene3D G3DSA:3.40.50.980 1003 1155 1.3E-44 T 06-07-2017 SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 SUPERFAMILY SSF56801 994 1538 1.83E-137 T 06-07-2017 SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 Gene3D G3DSA:2.30.38.10 1320 1398 6.8E-25 T 06-07-2017 SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 Pfam PF00550 Phosphopantetheine attachment site 463 523 3.0E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 Pfam PF00550 Phosphopantetheine attachment site 1527 1590 1.4E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 SUPERFAMILY SSF52777 561 736 4.0E-22 T 06-07-2017 SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 SMART SM00824 Thioesterase 1620 1877 0.0023 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 SUPERFAMILY SSF47336 1519 1591 2.36E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 Pfam PF00501 AMP-binding enzyme 1008 1409 1.3E-84 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 SUPERFAMILY SSF52777 743 980 9.78E-38 T 06-07-2017 SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 SUPERFAMILY SSF52777 9 179 9.45E-34 T 06-07-2017 SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1149 1160 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 Gene3D G3DSA:1.10.1200.10 454 524 2.2E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32230 89a54de5bfb6d43b63eff49ae1658417 1885 Gene3D G3DSA:1.10.1200.10 1530 1593 5.1E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS03295 4e7ea5f14a4015f664e0fdcb503cee73 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS03295 4e7ea5f14a4015f664e0fdcb503cee73 261 Pfam PF00106 short chain dehydrogenase 8 201 4.3E-63 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03295 4e7ea5f14a4015f664e0fdcb503cee73 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 188 0.0056 T 06-07-2017 SMD11_RS03295 4e7ea5f14a4015f664e0fdcb503cee73 261 SUPERFAMILY SSF51735 7 258 3.24E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03295 4e7ea5f14a4015f664e0fdcb503cee73 261 Gene3D G3DSA:3.40.50.720 6 258 1.3E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03295 4e7ea5f14a4015f664e0fdcb503cee73 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 9.2E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03295 4e7ea5f14a4015f664e0fdcb503cee73 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 9.2E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03295 4e7ea5f14a4015f664e0fdcb503cee73 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 9.2E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03295 4e7ea5f14a4015f664e0fdcb503cee73 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 9.2E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03295 4e7ea5f14a4015f664e0fdcb503cee73 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 9.2E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03295 4e7ea5f14a4015f664e0fdcb503cee73 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.2E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03295 4e7ea5f14a4015f664e0fdcb503cee73 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.3E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03295 4e7ea5f14a4015f664e0fdcb503cee73 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.3E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03295 4e7ea5f14a4015f664e0fdcb503cee73 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.3E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS15590 fccc356c5620834305cb9c925af28bb5 622 Gene3D G3DSA:2.120.10.30 119 328 1.6E-16 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS15590 fccc356c5620834305cb9c925af28bb5 622 Gene3D G3DSA:3.40.50.1820 61 102 5.5E-72 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15590 fccc356c5620834305cb9c925af28bb5 622 Gene3D G3DSA:3.40.50.1820 357 619 5.5E-72 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15590 fccc356c5620834305cb9c925af28bb5 622 SUPERFAMILY SSF82171 51 342 3.92E-25 T 06-07-2017 SMD11_RS15590 fccc356c5620834305cb9c925af28bb5 622 SUPERFAMILY SSF53474 378 619 4.95E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15590 fccc356c5620834305cb9c925af28bb5 622 Pfam PF00326 Prolyl oligopeptidase family 418 619 2.0E-40 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMD11_RS24825 73ab500737bcb518889607f30c1a2ee9 264 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 205 216 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site SMD11_RS24825 73ab500737bcb518889607f30c1a2ee9 264 Gene3D G3DSA:2.40.10.10 70 126 2.5E-14 T 06-07-2017 SMD11_RS24825 73ab500737bcb518889607f30c1a2ee9 264 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 117 131 1.7E-12 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD11_RS24825 73ab500737bcb518889607f30c1a2ee9 264 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 62 77 1.7E-12 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD11_RS24825 73ab500737bcb518889607f30c1a2ee9 264 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 204 216 1.7E-12 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD11_RS24825 73ab500737bcb518889607f30c1a2ee9 264 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 72 77 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD11_RS24825 73ab500737bcb518889607f30c1a2ee9 264 Pfam PF00089 Trypsin 40 253 1.8E-51 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD11_RS24825 73ab500737bcb518889607f30c1a2ee9 264 SMART SM00020 39 255 5.8E-67 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD11_RS24825 73ab500737bcb518889607f30c1a2ee9 264 SUPERFAMILY SSF50494 12 253 2.14E-62 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS24825 73ab500737bcb518889607f30c1a2ee9 264 Gene3D G3DSA:2.40.10.10 127 257 1.9E-37 T 06-07-2017 SMD11_RS24825 73ab500737bcb518889607f30c1a2ee9 264 Gene3D G3DSA:2.40.10.10 40 69 1.5E-14 T 06-07-2017 SMD11_RS18670 937b33dbc069a638a75622066f0a5008 223 Gene3D G3DSA:1.10.10.10 158 221 7.8E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS18670 937b33dbc069a638a75622066f0a5008 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 204 3.6E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS18670 937b33dbc069a638a75622066f0a5008 223 SMART SM00421 157 219 7.3E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS18670 937b33dbc069a638a75622066f0a5008 223 SMART SM00448 5 129 1.9E-9 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS18670 937b33dbc069a638a75622066f0a5008 223 SUPERFAMILY SSF52172 4 179 2.09E-15 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS18670 937b33dbc069a638a75622066f0a5008 223 Gene3D G3DSA:3.40.50.2300 4 157 1.2E-24 T 06-07-2017 SMD11_RS18670 937b33dbc069a638a75622066f0a5008 223 Pfam PF00072 Response regulator receiver domain 7 117 5.3E-14 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS18670 937b33dbc069a638a75622066f0a5008 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 2.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS18670 937b33dbc069a638a75622066f0a5008 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 2.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS18670 937b33dbc069a638a75622066f0a5008 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 2.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS18590 abc50df3d9f2809ae581434e3640f682 631 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 123 2.5E-24 T 06-07-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18590 abc50df3d9f2809ae581434e3640f682 631 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 3 625 3.4E-235 T 06-07-2017 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18590 abc50df3d9f2809ae581434e3640f682 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 86 106 5.4E-10 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMD11_RS18590 abc50df3d9f2809ae581434e3640f682 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 264 286 5.4E-10 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMD11_RS18590 abc50df3d9f2809ae581434e3640f682 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 420 442 5.4E-10 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMD11_RS18590 abc50df3d9f2809ae581434e3640f682 631 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 60 84 5.4E-10 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 SMD11_RS18590 abc50df3d9f2809ae581434e3640f682 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 3.9E-60 T 06-07-2017 SMD11_RS18590 abc50df3d9f2809ae581434e3640f682 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 3.9E-60 T 06-07-2017 SMD11_RS18590 abc50df3d9f2809ae581434e3640f682 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 3.9E-60 T 06-07-2017 SMD11_RS18590 abc50df3d9f2809ae581434e3640f682 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 246 272 3.9E-60 T 06-07-2017 SMD11_RS18590 abc50df3d9f2809ae581434e3640f682 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 3.9E-60 T 06-07-2017 SMD11_RS18590 abc50df3d9f2809ae581434e3640f682 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 314 326 3.9E-60 T 06-07-2017 SMD11_RS18590 abc50df3d9f2809ae581434e3640f682 631 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 421 440 3.9E-60 T 06-07-2017 SMD11_RS18590 abc50df3d9f2809ae581434e3640f682 631 Pfam PF00361 Proton-conducting membrane transporter 135 422 1.4E-81 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS05545 d07835864a6d7bcdb62e1dcadcd780e1 332 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 312 4.0E-61 T 06-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS05545 d07835864a6d7bcdb62e1dcadcd780e1 332 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 152 9.5E-54 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS05545 d07835864a6d7bcdb62e1dcadcd780e1 332 Gene3D G3DSA:3.30.360.10 161 314 9.3E-67 T 06-07-2017 SMD11_RS05545 d07835864a6d7bcdb62e1dcadcd780e1 332 SUPERFAMILY SSF55347 152 313 1.66E-63 T 06-07-2017 SMD11_RS05545 d07835864a6d7bcdb62e1dcadcd780e1 332 Gene3D G3DSA:3.40.50.720 1 160 5.3E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05545 d07835864a6d7bcdb62e1dcadcd780e1 332 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 06-07-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS05545 d07835864a6d7bcdb62e1dcadcd780e1 332 SUPERFAMILY SSF51735 3 166 9.87E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05545 d07835864a6d7bcdb62e1dcadcd780e1 332 SMART SM00846 2 152 1.8E-83 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS05545 d07835864a6d7bcdb62e1dcadcd780e1 332 PIRSF PIRSF000149 1 332 5.6E-124 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS05545 d07835864a6d7bcdb62e1dcadcd780e1 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 8.5E-34 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS05545 d07835864a6d7bcdb62e1dcadcd780e1 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 8.5E-34 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS05545 d07835864a6d7bcdb62e1dcadcd780e1 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 8.5E-34 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS05545 d07835864a6d7bcdb62e1dcadcd780e1 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 8.5E-34 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS05545 d07835864a6d7bcdb62e1dcadcd780e1 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 8.5E-34 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS05545 d07835864a6d7bcdb62e1dcadcd780e1 332 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 324 7.2E-126 T 06-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS33165 30bbc11e0a3255de5f9c13a36eee398f 187 TIGRFAM TIGR02242 tail_TIGR02242: phage tail protein domain 18 118 2.6E-28 T 06-07-2017 IPR011748 Uncharacterised protein family, phage tail-like SMD11_RS33165 30bbc11e0a3255de5f9c13a36eee398f 187 Pfam PF09684 Phage tail protein (Tail_P2_I) 36 142 1.3E-13 T 06-07-2017 IPR006521 Tail protein I SMD11_RS31980 130d4f979d8c32a22b7d31ca30946cd7 386 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 314 320 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMD11_RS31980 130d4f979d8c32a22b7d31ca30946cd7 386 Hamap MF_01859 Ribosomal RNA large subunit methyltransferase G [rlmG]. 1 385 46.331 T 06-07-2017 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD11_RS31980 130d4f979d8c32a22b7d31ca30946cd7 386 Pfam PF05175 Methyltransferase small domain 212 382 1.2E-54 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 SMD11_RS31980 130d4f979d8c32a22b7d31ca30946cd7 386 Gene3D G3DSA:3.40.50.150 208 384 9.6E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS31980 130d4f979d8c32a22b7d31ca30946cd7 386 PIRSF PIRSF037565 1 386 1.1E-138 T 06-07-2017 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD11_RS31980 130d4f979d8c32a22b7d31ca30946cd7 386 SUPERFAMILY SSF53335 223 360 8.13E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29825 ee13ba8e4f073a3431f0d943f42e6ffe 785 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 322 338 5.2E-36 T 06-07-2017 SMD11_RS29825 ee13ba8e4f073a3431f0d943f42e6ffe 785 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 5.2E-36 T 06-07-2017 SMD11_RS29825 ee13ba8e4f073a3431f0d943f42e6ffe 785 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 271 286 5.2E-36 T 06-07-2017 SMD11_RS29825 ee13ba8e4f073a3431f0d943f42e6ffe 785 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 5.2E-36 T 06-07-2017 SMD11_RS29825 ee13ba8e4f073a3431f0d943f42e6ffe 785 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 302 5.2E-36 T 06-07-2017 SMD11_RS29825 ee13ba8e4f073a3431f0d943f42e6ffe 785 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 322 5.2E-36 T 06-07-2017 SMD11_RS29825 ee13ba8e4f073a3431f0d943f42e6ffe 785 SUPERFAMILY SSF51905 258 345 1.17E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29825 ee13ba8e4f073a3431f0d943f42e6ffe 785 SUPERFAMILY SSF51905 9 170 1.17E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29825 ee13ba8e4f073a3431f0d943f42e6ffe 785 Pfam PF01494 FAD binding domain 8 334 6.7E-70 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS29825 ee13ba8e4f073a3431f0d943f42e6ffe 785 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 679 707 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS29825 ee13ba8e4f073a3431f0d943f42e6ffe 785 SUPERFAMILY SSF51735 537 783 1.46E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29825 ee13ba8e4f073a3431f0d943f42e6ffe 785 Gene3D G3DSA:3.40.50.720 532 783 3.9E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29825 ee13ba8e4f073a3431f0d943f42e6ffe 785 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 545 781 5.8E-45 T 06-07-2017 SMD11_RS29825 ee13ba8e4f073a3431f0d943f42e6ffe 785 Gene3D G3DSA:3.50.50.60 259 338 1.7E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29825 ee13ba8e4f073a3431f0d943f42e6ffe 785 Gene3D G3DSA:3.50.50.60 8 175 1.7E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS14730 15f61318850f555aea547630f0f68957 377 Pfam PF10635 DisA bacterial checkpoint controller linker region 158 300 7.3E-51 T 06-07-2017 IPR018906 DNA integrity scanning, DisA, linker region SMD11_RS14730 15f61318850f555aea547630f0f68957 377 Gene3D G3DSA:1.10.150.20 316 364 2.2E-11 T 06-07-2017 SMD11_RS14730 15f61318850f555aea547630f0f68957 377 Pfam PF12826 Helix-hairpin-helix motif 327 364 2.4E-6 T 06-07-2017 SMD11_RS14730 15f61318850f555aea547630f0f68957 377 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 41 154 2.7E-22 T 06-07-2017 IPR003390 DNA integrity scanning protein, DisA, N-terminal SMD11_RS14730 15f61318850f555aea547630f0f68957 377 Gene3D G3DSA:3.40.1700.10 34 157 1.1E-29 T 06-07-2017 SMD11_RS14730 15f61318850f555aea547630f0f68957 377 SUPERFAMILY SSF143597 35 156 4.84E-26 T 06-07-2017 SMD11_RS14730 15f61318850f555aea547630f0f68957 377 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 25 374 43.511 T 06-07-2017 IPR023763 DNA integrity scanning protein, DisA SMD11_RS14730 15f61318850f555aea547630f0f68957 377 SUPERFAMILY SSF47781 300 369 3.0E-12 T 06-07-2017 IPR010994 RuvA domain 2-like SMD11_RS20530 7ef5aa7e6db1aac78b74d8547a248ba6 296 SUPERFAMILY SSF88946 39 144 1.88E-31 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20530 7ef5aa7e6db1aac78b74d8547a248ba6 296 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 70 292 5.0E-92 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20530 7ef5aa7e6db1aac78b74d8547a248ba6 296 Gene3D G3DSA:1.10.10.10 143 198 4.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20530 7ef5aa7e6db1aac78b74d8547a248ba6 296 Pfam PF04542 Sigma-70 region 2 75 144 4.3E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20530 7ef5aa7e6db1aac78b74d8547a248ba6 296 PRINTS PR00046 Major sigma-70 factor signature 99 112 2.6E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20530 7ef5aa7e6db1aac78b74d8547a248ba6 296 PRINTS PR00046 Major sigma-70 factor signature 245 257 2.6E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20530 7ef5aa7e6db1aac78b74d8547a248ba6 296 PRINTS PR00046 Major sigma-70 factor signature 262 277 2.6E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20530 7ef5aa7e6db1aac78b74d8547a248ba6 296 Pfam PF04545 Sigma-70, region 4 242 290 8.8E-17 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20530 7ef5aa7e6db1aac78b74d8547a248ba6 296 SUPERFAMILY SSF88659 226 292 1.87E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20530 7ef5aa7e6db1aac78b74d8547a248ba6 296 SUPERFAMILY SSF88659 148 215 1.0E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20530 7ef5aa7e6db1aac78b74d8547a248ba6 296 Pfam PF04539 Sigma-70 region 3 154 222 1.9E-16 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20530 7ef5aa7e6db1aac78b74d8547a248ba6 296 Gene3D G3DSA:1.10.601.10 60 142 4.5E-25 T 06-07-2017 SMD11_RS20530 7ef5aa7e6db1aac78b74d8547a248ba6 296 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 72 290 1.7E-31 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20530 7ef5aa7e6db1aac78b74d8547a248ba6 296 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 99 112 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20530 7ef5aa7e6db1aac78b74d8547a248ba6 296 Gene3D G3DSA:1.10.10.10 238 292 5.5E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33925 2dc37a61a9b5e6bc6bf0a082b59b0b23 478 Pfam PF07690 Major Facilitator Superfamily 17 408 9.9E-64 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS33925 2dc37a61a9b5e6bc6bf0a082b59b0b23 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 266 291 3.5E-6 T 06-07-2017 SMD11_RS33925 2dc37a61a9b5e6bc6bf0a082b59b0b23 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 3.5E-6 T 06-07-2017 SMD11_RS33925 2dc37a61a9b5e6bc6bf0a082b59b0b23 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 3.5E-6 T 06-07-2017 SMD11_RS33925 2dc37a61a9b5e6bc6bf0a082b59b0b23 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 106 126 3.5E-6 T 06-07-2017 SMD11_RS33925 2dc37a61a9b5e6bc6bf0a082b59b0b23 478 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 13 417 7.2E-74 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS33925 2dc37a61a9b5e6bc6bf0a082b59b0b23 478 SUPERFAMILY SSF103473 247 461 1.2E-76 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS33925 2dc37a61a9b5e6bc6bf0a082b59b0b23 478 SUPERFAMILY SSF103473 4 196 1.2E-76 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS33925 2dc37a61a9b5e6bc6bf0a082b59b0b23 478 Gene3D G3DSA:1.20.1250.20 10 196 1.5E-35 T 06-07-2017 SMD11_RS33925 2dc37a61a9b5e6bc6bf0a082b59b0b23 478 Gene3D G3DSA:1.20.1250.20 261 471 3.3E-23 T 06-07-2017 SMD11_RS00355 4c19041db9322e7287a912c9b7dc76d7 187 Gene3D G3DSA:1.10.1900.10 11 61 2.0E-4 T 06-07-2017 IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein GO:0003723 SMD11_RS00355 4c19041db9322e7287a912c9b7dc76d7 187 SUPERFAMILY SSF158560 18 62 2.62E-8 T 06-07-2017 SMD11_RS13900 6db331ff47d080fd928110bf2376f0cf 506 Pfam PF02378 Phosphotransferase system, EIIC 143 410 4.8E-26 T 06-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SMD11_RS13900 6db331ff47d080fd928110bf2376f0cf 506 Gene3D G3DSA:3.30.1360.60 11 87 3.8E-22 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SMD11_RS13900 6db331ff47d080fd928110bf2376f0cf 506 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 26 43 - T 06-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SMD11_RS13900 6db331ff47d080fd928110bf2376f0cf 506 SUPERFAMILY SSF55604 14 85 6.54E-17 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SMD11_RS13900 6db331ff47d080fd928110bf2376f0cf 506 Pfam PF00367 phosphotransferase system, EIIB 17 47 3.4E-12 T 06-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SMD11_RS23595 cfb10a16e8f2a24950eb56b7e73a6b67 358 SUPERFAMILY SSF51735 150 324 2.03E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS23595 cfb10a16e8f2a24950eb56b7e73a6b67 358 Gene3D G3DSA:3.40.50.720 183 298 5.5E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS23595 cfb10a16e8f2a24950eb56b7e73a6b67 358 Pfam PF00107 Zinc-binding dehydrogenase 189 312 2.0E-25 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS23595 cfb10a16e8f2a24950eb56b7e73a6b67 358 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD11_RS23595 cfb10a16e8f2a24950eb56b7e73a6b67 358 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 146 1.9E-26 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS23595 cfb10a16e8f2a24950eb56b7e73a6b67 358 SMART SM00829 10 352 3.6E-7 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS23595 cfb10a16e8f2a24950eb56b7e73a6b67 358 SUPERFAMILY SSF50129 1 181 8.67E-49 T 06-07-2017 IPR011032 GroES-like SMD11_RS23595 cfb10a16e8f2a24950eb56b7e73a6b67 358 Gene3D G3DSA:3.90.180.10 1 182 8.9E-56 T 06-07-2017 IPR011032 GroES-like SMD11_RS23395 ab9492830b78788275da2c4b27908d26 130 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 49 92 4.3E-10 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS23395 ab9492830b78788275da2c4b27908d26 130 SUPERFAMILY SSF69118 11 114 8.9E-16 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS23395 ab9492830b78788275da2c4b27908d26 130 Pfam PF02627 Carboxymuconolactone decarboxylase family 37 106 4.2E-9 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS23395 ab9492830b78788275da2c4b27908d26 130 Gene3D G3DSA:1.20.1290.10 8 109 4.4E-16 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS16345 6aa56b0beaaa04e35e1e4c880fb36c6f 536 Gene3D G3DSA:1.20.1250.20 483 508 5.1E-22 T 06-07-2017 SMD11_RS16345 6aa56b0beaaa04e35e1e4c880fb36c6f 536 Gene3D G3DSA:1.20.1250.20 267 424 5.1E-22 T 06-07-2017 SMD11_RS16345 6aa56b0beaaa04e35e1e4c880fb36c6f 536 SUPERFAMILY SSF103473 481 510 3.01E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS16345 6aa56b0beaaa04e35e1e4c880fb36c6f 536 SUPERFAMILY SSF103473 4 204 3.01E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS16345 6aa56b0beaaa04e35e1e4c880fb36c6f 536 SUPERFAMILY SSF103473 252 423 3.01E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS16345 6aa56b0beaaa04e35e1e4c880fb36c6f 536 Gene3D G3DSA:1.20.1250.20 18 195 3.8E-28 T 06-07-2017 SMD11_RS16345 6aa56b0beaaa04e35e1e4c880fb36c6f 536 PRINTS PR01036 Tetracycline resistance protein TetB signature 82 104 3.6E-14 T 06-07-2017 SMD11_RS16345 6aa56b0beaaa04e35e1e4c880fb36c6f 536 PRINTS PR01036 Tetracycline resistance protein TetB signature 143 167 3.6E-14 T 06-07-2017 SMD11_RS16345 6aa56b0beaaa04e35e1e4c880fb36c6f 536 PRINTS PR01036 Tetracycline resistance protein TetB signature 168 192 3.6E-14 T 06-07-2017 SMD11_RS16345 6aa56b0beaaa04e35e1e4c880fb36c6f 536 PRINTS PR01036 Tetracycline resistance protein TetB signature 22 46 3.6E-14 T 06-07-2017 SMD11_RS16345 6aa56b0beaaa04e35e1e4c880fb36c6f 536 PRINTS PR01036 Tetracycline resistance protein TetB signature 404 423 3.6E-14 T 06-07-2017 SMD11_RS16345 6aa56b0beaaa04e35e1e4c880fb36c6f 536 Pfam PF07690 Major Facilitator Superfamily 23 409 3.2E-53 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS08435 5f36bf2771d8582b700075978c7c1cf6 373 SUPERFAMILY SSF51569 15 368 2.93E-40 T 06-07-2017 SMD11_RS08435 5f36bf2771d8582b700075978c7c1cf6 373 PIRSF PIRSF036915 3 372 1.2E-98 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS08435 5f36bf2771d8582b700075978c7c1cf6 373 Hamap MF_00493 Transaldolase [tal]. 1 373 86.917 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS08435 5f36bf2771d8582b700075978c7c1cf6 373 Pfam PF00923 Transaldolase 24 362 4.9E-41 T 06-07-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 SMD11_RS08435 5f36bf2771d8582b700075978c7c1cf6 373 Gene3D G3DSA:3.20.20.70 13 364 6.9E-70 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS19285 1fedde40c6b03234d596e8b8a592ee95 568 SUPERFAMILY SSF51905 290 351 1.1E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS19285 1fedde40c6b03234d596e8b8a592ee95 568 SUPERFAMILY SSF51905 24 253 1.1E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS19285 1fedde40c6b03234d596e8b8a592ee95 568 Pfam PF01266 FAD dependent oxidoreductase 24 377 4.3E-49 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD11_RS19285 1fedde40c6b03234d596e8b8a592ee95 568 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 404 528 2.1E-31 T 06-07-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 SMD11_RS19285 1fedde40c6b03234d596e8b8a592ee95 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 23 35 3.0E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 SMD11_RS19285 1fedde40c6b03234d596e8b8a592ee95 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 52 64 3.0E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 SMD11_RS19285 1fedde40c6b03234d596e8b8a592ee95 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 46 3.0E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 SMD11_RS19285 1fedde40c6b03234d596e8b8a592ee95 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 341 347 3.0E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 SMD11_RS19285 1fedde40c6b03234d596e8b8a592ee95 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 98 110 3.0E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 SMD11_RS19285 1fedde40c6b03234d596e8b8a592ee95 568 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 371 383 3.0E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 SMD11_RS19285 1fedde40c6b03234d596e8b8a592ee95 568 Gene3D G3DSA:3.50.50.60 20 257 2.4E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS19285 1fedde40c6b03234d596e8b8a592ee95 568 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 376 386 - T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 SMD11_RS08325 bbf3b4059e2f588c068476124944f17c 445 Gene3D G3DSA:2.40.50.140 11 85 2.4E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS08325 bbf3b4059e2f588c068476124944f17c 445 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 262 342 2.1E-5 T 06-07-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 SMD11_RS08325 bbf3b4059e2f588c068476124944f17c 445 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 366 439 4.8E-9 T 06-07-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 SMD11_RS08325 bbf3b4059e2f588c068476124944f17c 445 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 423 433 - T 06-07-2017 IPR030391 RNA methyltransferase TrmA, conserved site SMD11_RS08325 bbf3b4059e2f588c068476124944f17c 445 Pfam PF01938 TRAM domain 8 67 4.8E-13 T 06-07-2017 IPR002792 TRAM domain SMD11_RS08325 bbf3b4059e2f588c068476124944f17c 445 SUPERFAMILY SSF50249 13 73 6.85E-10 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS08325 bbf3b4059e2f588c068476124944f17c 445 SUPERFAMILY SSF53335 75 440 2.07E-53 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS08325 bbf3b4059e2f588c068476124944f17c 445 Gene3D G3DSA:3.40.50.150 243 439 1.3E-51 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS19015 5693aa12608fe9d2ac6366ac44df9ab9 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 26.714 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS19015 5693aa12608fe9d2ac6366ac44df9ab9 126 PIRSF PIRSF002134 1 125 3.1E-41 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS19015 5693aa12608fe9d2ac6366ac44df9ab9 126 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 06-07-2017 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS19015 5693aa12608fe9d2ac6366ac44df9ab9 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 6.4E-50 T 06-07-2017 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS19015 5693aa12608fe9d2ac6366ac44df9ab9 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 5.2E-30 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS19015 5693aa12608fe9d2ac6366ac44df9ab9 126 Gene3D G3DSA:1.10.8.50 1 72 2.8E-28 T 06-07-2017 SMD11_RS19015 5693aa12608fe9d2ac6366ac44df9ab9 126 Gene3D G3DSA:4.10.910.10 73 124 3.8E-25 T 06-07-2017 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS19015 5693aa12608fe9d2ac6366ac44df9ab9 126 SUPERFAMILY SSF46946 2 122 2.94E-42 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMD11_RS03840 264e2d9805368f272716f5352efddd70 279 Gene3D G3DSA:3.40.50.720 31 274 4.4E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03840 264e2d9805368f272716f5352efddd70 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 174 202 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS03840 264e2d9805368f272716f5352efddd70 279 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 42 274 9.4E-60 T 06-07-2017 SMD11_RS03840 264e2d9805368f272716f5352efddd70 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 177 4.4E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03840 264e2d9805368f272716f5352efddd70 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 37 54 4.4E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03840 264e2d9805368f272716f5352efddd70 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 242 262 4.4E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03840 264e2d9805368f272716f5352efddd70 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 206 4.4E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03840 264e2d9805368f272716f5352efddd70 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 225 4.4E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03840 264e2d9805368f272716f5352efddd70 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 124 4.4E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03840 264e2d9805368f272716f5352efddd70 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 175 6.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03840 264e2d9805368f272716f5352efddd70 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 187 206 6.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03840 264e2d9805368f272716f5352efddd70 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 113 124 6.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03840 264e2d9805368f272716f5352efddd70 279 SUPERFAMILY SSF51735 34 275 7.36E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29330 133da0c4c618ec6511403429fea6ff7c 700 Gene3D G3DSA:3.40.50.740 317 341 2.2E-65 T 06-07-2017 SMD11_RS29330 133da0c4c618ec6511403429fea6ff7c 700 Gene3D G3DSA:3.40.50.740 376 526 2.2E-65 T 06-07-2017 SMD11_RS29330 133da0c4c618ec6511403429fea6ff7c 700 Gene3D G3DSA:3.40.50.740 62 136 2.2E-65 T 06-07-2017 SMD11_RS29330 133da0c4c618ec6511403429fea6ff7c 700 Pfam PF01568 Molydopterin dinucleotide binding domain 581 688 7.6E-35 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMD11_RS29330 133da0c4c618ec6511403429fea6ff7c 700 Gene3D G3DSA:2.20.25.90 4 56 6.1E-16 T 06-07-2017 SMD11_RS29330 133da0c4c618ec6511403429fea6ff7c 700 SUPERFAMILY SSF53706 2 583 5.63E-167 T 06-07-2017 SMD11_RS29330 133da0c4c618ec6511403429fea6ff7c 700 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 3 55 2.0E-11 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS29330 133da0c4c618ec6511403429fea6ff7c 700 Gene3D G3DSA:2.40.40.20 533 694 2.9E-63 T 06-07-2017 SMD11_RS29330 133da0c4c618ec6511403429fea6ff7c 700 SUPERFAMILY SSF50692 543 694 1.65E-50 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain SMD11_RS29330 133da0c4c618ec6511403429fea6ff7c 700 SMART SM00926 3 59 6.2E-11 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS29330 133da0c4c618ec6511403429fea6ff7c 700 Pfam PF00384 Molybdopterin oxidoreductase 62 490 2.9E-71 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS29330 133da0c4c618ec6511403429fea6ff7c 700 Gene3D G3DSA:3.40.228.10 138 316 4.3E-53 T 06-07-2017 SMD11_RS15125 b26c9949ec2abecaecdff66755389402 285 Pfam PF00149 Calcineurin-like phosphoesterase 5 239 4.0E-17 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 SMD11_RS15125 b26c9949ec2abecaecdff66755389402 285 SUPERFAMILY SSF56300 171 262 8.7E-25 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS15125 b26c9949ec2abecaecdff66755389402 285 SUPERFAMILY SSF56300 5 131 8.7E-25 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS15125 b26c9949ec2abecaecdff66755389402 285 Gene3D G3DSA:3.60.21.10 5 70 1.9E-23 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS15125 b26c9949ec2abecaecdff66755389402 285 Gene3D G3DSA:3.60.21.10 173 264 1.9E-23 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS02700 bea42de3c1aaea69d40dd6ff4bf92e2f 328 Gene3D G3DSA:1.10.3720.10 103 324 5.5E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS02700 bea42de3c1aaea69d40dd6ff4bf92e2f 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 328 4.4E-32 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS02700 bea42de3c1aaea69d40dd6ff4bf92e2f 328 SUPERFAMILY SSF161098 103 315 3.71E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS18790 14b95bbd636c4b2809871d66b0cb13c9 351 SUPERFAMILY SSF56194 211 349 1.57E-33 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS18790 14b95bbd636c4b2809871d66b0cb13c9 351 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 213 347 9.9E-39 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS18790 14b95bbd636c4b2809871d66b0cb13c9 351 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 343 2.5E-49 T 06-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS18790 14b95bbd636c4b2809871d66b0cb13c9 351 Gene3D G3DSA:3.90.78.10 240 350 7.5E-45 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS18790 14b95bbd636c4b2809871d66b0cb13c9 351 Gene3D G3DSA:3.30.465.10 223 239 1.2E-48 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS18790 14b95bbd636c4b2809871d66b0cb13c9 351 Gene3D G3DSA:3.30.465.10 76 188 1.2E-48 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS18790 14b95bbd636c4b2809871d66b0cb13c9 351 Pfam PF01565 FAD binding domain 23 149 1.7E-19 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD11_RS18790 14b95bbd636c4b2809871d66b0cb13c9 351 SUPERFAMILY SSF56176 8 186 2.52E-36 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS18790 14b95bbd636c4b2809871d66b0cb13c9 351 Gene3D G3DSA:3.30.43.10 8 72 4.0E-23 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS18790 14b95bbd636c4b2809871d66b0cb13c9 351 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 351 76.968 T 06-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS01840 31f6e22c0f23c8ab4946c1d968b0c793 390 Gene3D G3DSA:3.40.710.10 52 385 6.3E-72 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS01840 31f6e22c0f23c8ab4946c1d968b0c793 390 Pfam PF00144 Beta-lactamase 55 361 3.4E-50 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS01840 31f6e22c0f23c8ab4946c1d968b0c793 390 SUPERFAMILY SSF56601 50 375 5.91E-69 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS24190 f1277cdf1b4b06c08e53e28f515df548 323 SUPERFAMILY SSF81464 26 124 1.37E-19 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24190 f1277cdf1b4b06c08e53e28f515df548 323 Gene3D G3DSA:1.10.287.90 41 124 2.7E-15 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24190 f1277cdf1b4b06c08e53e28f515df548 323 Gene3D G3DSA:2.60.40.420 136 295 5.5E-39 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS24190 f1277cdf1b4b06c08e53e28f515df548 323 SUPERFAMILY SSF49503 206 305 7.57E-39 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS24190 f1277cdf1b4b06c08e53e28f515df548 323 SUPERFAMILY SSF49503 132 157 7.57E-39 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS24190 f1277cdf1b4b06c08e53e28f515df548 323 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 52 292 5.3E-46 T 06-07-2017 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24190 f1277cdf1b4b06c08e53e28f515df548 323 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 213 283 1.4E-15 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24190 f1277cdf1b4b06c08e53e28f515df548 323 PRINTS PR01166 Cytochrome c oxidase subunit II signature 228 248 1.6E-12 T 06-07-2017 SMD11_RS24190 f1277cdf1b4b06c08e53e28f515df548 323 PRINTS PR01166 Cytochrome c oxidase subunit II signature 266 283 1.6E-12 T 06-07-2017 SMD11_RS24190 f1277cdf1b4b06c08e53e28f515df548 323 PRINTS PR01166 Cytochrome c oxidase subunit II signature 134 153 1.6E-12 T 06-07-2017 SMD11_RS24190 f1277cdf1b4b06c08e53e28f515df548 323 PRINTS PR01166 Cytochrome c oxidase subunit II signature 248 265 1.6E-12 T 06-07-2017 SMD11_RS24190 f1277cdf1b4b06c08e53e28f515df548 323 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 111 1.6E-12 T 06-07-2017 SMD11_RS24190 f1277cdf1b4b06c08e53e28f515df548 323 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 229 277 - T 06-07-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS13965 96a7ff6f9120c38745f554e01b1aa8f2 392 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 3 383 1.0E-78 T 06-07-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 SMD11_RS13965 96a7ff6f9120c38745f554e01b1aa8f2 392 Gene3D G3DSA:3.20.20.140 61 356 1.8E-101 T 06-07-2017 SMD11_RS13965 96a7ff6f9120c38745f554e01b1aa8f2 392 Pfam PF01979 Amidohydrolase family 57 386 5.0E-30 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 SMD11_RS13965 96a7ff6f9120c38745f554e01b1aa8f2 392 SUPERFAMILY SSF51338 3 60 1.25E-17 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS13965 96a7ff6f9120c38745f554e01b1aa8f2 392 SUPERFAMILY SSF51338 357 387 1.25E-17 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS13965 96a7ff6f9120c38745f554e01b1aa8f2 392 PIRSF PIRSF038994 3 390 1.2E-108 T 06-07-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 SMD11_RS13965 96a7ff6f9120c38745f554e01b1aa8f2 392 Gene3D G3DSA:2.30.40.10 3 60 6.5E-14 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS13965 96a7ff6f9120c38745f554e01b1aa8f2 392 Gene3D G3DSA:2.30.40.10 357 372 6.5E-14 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS13965 96a7ff6f9120c38745f554e01b1aa8f2 392 SUPERFAMILY SSF51556 60 357 2.09E-90 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS12755 85bade14164d4e3105b70e83f850c283 439 Gene3D G3DSA:1.20.1250.20 44 224 3.0E-28 T 06-07-2017 SMD11_RS12755 85bade14164d4e3105b70e83f850c283 439 Gene3D G3DSA:1.20.1250.20 247 418 4.2E-9 T 06-07-2017 SMD11_RS12755 85bade14164d4e3105b70e83f850c283 439 ProSitePatterns PS00216 Sugar transport proteins signature 1. 99 115 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS12755 85bade14164d4e3105b70e83f850c283 439 SUPERFAMILY SSF103473 33 421 1.26E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS12755 85bade14164d4e3105b70e83f850c283 439 Pfam PF07690 Major Facilitator Superfamily 50 385 4.3E-38 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS32845 957407143f5a925704d934968e7b917b 304 Gene3D G3DSA:3.40.190.10 89 181 4.2E-16 T 06-07-2017 SMD11_RS32845 957407143f5a925704d934968e7b917b 304 Gene3D G3DSA:3.40.190.10 182 271 4.1E-25 T 06-07-2017 SMD11_RS32845 957407143f5a925704d934968e7b917b 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.4E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS32845 957407143f5a925704d934968e7b917b 304 SUPERFAMILY SSF53850 89 303 9.5E-37 T 06-07-2017 SMD11_RS32845 957407143f5a925704d934968e7b917b 304 Gene3D G3DSA:1.10.10.10 2 88 2.4E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32845 957407143f5a925704d934968e7b917b 304 Pfam PF03466 LysR substrate binding domain 88 298 3.1E-38 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS32845 957407143f5a925704d934968e7b917b 304 SUPERFAMILY SSF46785 2 110 1.49E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21520 d85a7b3ca8ca2ff5d123dc9388496a93 349 SUPERFAMILY SSF51989 48 348 1.1E-89 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS21520 d85a7b3ca8ca2ff5d123dc9388496a93 349 Pfam PF01341 Glycosyl hydrolases family 6 77 329 2.3E-83 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS21520 d85a7b3ca8ca2ff5d123dc9388496a93 349 PRINTS PR00733 Glycosyl hydrolase family 6 signature 81 100 8.8E-40 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS21520 d85a7b3ca8ca2ff5d123dc9388496a93 349 PRINTS PR00733 Glycosyl hydrolase family 6 signature 311 325 8.8E-40 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS21520 d85a7b3ca8ca2ff5d123dc9388496a93 349 PRINTS PR00733 Glycosyl hydrolase family 6 signature 267 280 8.8E-40 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS21520 d85a7b3ca8ca2ff5d123dc9388496a93 349 PRINTS PR00733 Glycosyl hydrolase family 6 signature 121 134 8.8E-40 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS21520 d85a7b3ca8ca2ff5d123dc9388496a93 349 PRINTS PR00733 Glycosyl hydrolase family 6 signature 206 219 8.8E-40 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS21520 d85a7b3ca8ca2ff5d123dc9388496a93 349 PRINTS PR00733 Glycosyl hydrolase family 6 signature 149 164 8.8E-40 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS21520 d85a7b3ca8ca2ff5d123dc9388496a93 349 PRINTS PR00733 Glycosyl hydrolase family 6 signature 237 247 8.8E-40 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS21520 d85a7b3ca8ca2ff5d123dc9388496a93 349 PRINTS PR00733 Glycosyl hydrolase family 6 signature 287 307 8.8E-40 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS21520 d85a7b3ca8ca2ff5d123dc9388496a93 349 PIRSF PIRSF001100 7 349 1.5E-98 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS21520 d85a7b3ca8ca2ff5d123dc9388496a93 349 Gene3D G3DSA:3.20.20.40 59 347 1.9E-98 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS26385 8ca118baf49e2c9d4b724cef918b1fc8 320 SUPERFAMILY SSF63829 26 302 1.18E-17 T 06-07-2017 SMD11_RS26385 8ca118baf49e2c9d4b724cef918b1fc8 320 Gene3D G3DSA:2.120.10.30 48 300 6.9E-13 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS03285 105c4db7a7a11f4c378136fc75df14c0 325 Pfam PF00248 Aldo/keto reductase family 15 306 4.1E-67 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS03285 105c4db7a7a11f4c378136fc75df14c0 325 Gene3D G3DSA:3.20.20.100 1 314 2.7E-105 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS03285 105c4db7a7a11f4c378136fc75df14c0 325 SUPERFAMILY SSF51430 1 310 8.51E-96 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS22800 ea4d30d52e36f9cf5b4b459d9ae0c589 313 Gene3D G3DSA:3.40.50.300 18 203 3.9E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22800 ea4d30d52e36f9cf5b4b459d9ae0c589 313 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 19 143 2.6E-16 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 SMD11_RS22800 ea4d30d52e36f9cf5b4b459d9ae0c589 313 SUPERFAMILY SSF52540 18 225 4.36E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22800 ea4d30d52e36f9cf5b4b459d9ae0c589 313 Pfam PF07650 KH domain 220 302 1.1E-16 T 06-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS22800 ea4d30d52e36f9cf5b4b459d9ae0c589 313 Hamap MF_00367 GTPase Era [era]. 12 313 34.343 T 06-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 SMD11_RS22800 ea4d30d52e36f9cf5b4b459d9ae0c589 313 Pfam PF01926 50S ribosome-binding GTPase 18 131 3.6E-20 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS22800 ea4d30d52e36f9cf5b4b459d9ae0c589 313 TIGRFAM TIGR00436 era: GTP-binding protein Era 15 296 1.7E-65 T 06-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 SMD11_RS22800 ea4d30d52e36f9cf5b4b459d9ae0c589 313 Gene3D G3DSA:3.30.300.20 204 310 1.8E-36 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta SMD11_RS22800 ea4d30d52e36f9cf5b4b459d9ae0c589 313 SUPERFAMILY SSF54814 194 313 6.47E-35 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 SMD11_RS07785 7b5c6e326ae8f3a57aa7278b53d2e067 631 Pfam PF00931 NB-ARC domain 308 549 2.8E-13 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 SMD11_RS07785 7b5c6e326ae8f3a57aa7278b53d2e067 631 SUPERFAMILY SSF52540 291 556 8.57E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07785 7b5c6e326ae8f3a57aa7278b53d2e067 631 PRINTS PR00364 Disease resistance protein signature 490 504 2.6E-8 T 06-07-2017 SMD11_RS07785 7b5c6e326ae8f3a57aa7278b53d2e067 631 PRINTS PR00364 Disease resistance protein signature 405 419 2.6E-8 T 06-07-2017 SMD11_RS07785 7b5c6e326ae8f3a57aa7278b53d2e067 631 PRINTS PR00364 Disease resistance protein signature 328 343 2.6E-8 T 06-07-2017 SMD11_RS07785 7b5c6e326ae8f3a57aa7278b53d2e067 631 Pfam PF03704 Bacterial transcriptional activator domain 103 241 1.1E-31 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS07785 7b5c6e326ae8f3a57aa7278b53d2e067 631 Gene3D G3DSA:1.10.10.10 11 96 3.1E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07785 7b5c6e326ae8f3a57aa7278b53d2e067 631 SUPERFAMILY SSF48452 98 257 9.23E-26 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS07785 7b5c6e326ae8f3a57aa7278b53d2e067 631 SMART SM00862 16 96 7.0E-5 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS07785 7b5c6e326ae8f3a57aa7278b53d2e067 631 SMART SM01043 103 245 8.7E-33 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS07785 7b5c6e326ae8f3a57aa7278b53d2e067 631 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 95 1.4E-6 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS07785 7b5c6e326ae8f3a57aa7278b53d2e067 631 SUPERFAMILY SSF46894 3 96 3.97E-11 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS07785 7b5c6e326ae8f3a57aa7278b53d2e067 631 Gene3D G3DSA:3.40.50.300 309 441 7.7E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24150 1f2a3fb22b3f885e7a89a051dbb62ea2 427 SMART SM00387 322 419 0.0065 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS24150 1f2a3fb22b3f885e7a89a051dbb62ea2 427 SUPERFAMILY SSF55874 324 417 8.88E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS24150 1f2a3fb22b3f885e7a89a051dbb62ea2 427 Gene3D G3DSA:3.30.565.10 329 418 2.3E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS24150 1f2a3fb22b3f885e7a89a051dbb62ea2 427 Pfam PF07730 Histidine kinase 196 260 1.8E-18 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS16430 355407c3e924f42c4b52aea3c8ce5579 158 SUPERFAMILY SSF110087 33 151 3.53E-28 T 06-07-2017 IPR007410 DR1885-like metal-binding protein SMD11_RS16430 355407c3e924f42c4b52aea3c8ce5579 158 Pfam PF04314 Protein of unknown function (DUF461) 48 145 2.2E-24 T 06-07-2017 IPR007410 DR1885-like metal-binding protein SMD11_RS22140 45dbb41f4ca21b907a2880ff809cc684 991 Gene3D G3DSA:3.30.379.10 37 186 5.8E-13 T 06-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS22140 45dbb41f4ca21b907a2880ff809cc684 991 SUPERFAMILY SSF51445 191 495 1.68E-81 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS22140 45dbb41f4ca21b907a2880ff809cc684 991 SUPERFAMILY SSF140657 511 637 4.84E-18 T 06-07-2017 SMD11_RS22140 45dbb41f4ca21b907a2880ff809cc684 991 Pfam PF07555 beta-N-acetylglucosaminidase 192 498 4.1E-95 T 06-07-2017 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 SMD11_RS22140 45dbb41f4ca21b907a2880ff809cc684 991 SUPERFAMILY SSF49785 855 981 2.76E-20 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS22140 45dbb41f4ca21b907a2880ff809cc684 991 Gene3D G3DSA:2.60.120.260 848 985 2.3E-24 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS22140 45dbb41f4ca21b907a2880ff809cc684 991 SUPERFAMILY SSF55545 38 187 4.84E-12 T 06-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS22140 45dbb41f4ca21b907a2880ff809cc684 991 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 39 186 8.1E-17 T 06-07-2017 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 SMD11_RS22140 45dbb41f4ca21b907a2880ff809cc684 991 Pfam PF00754 F5/8 type C domain 864 976 6.6E-20 T 06-07-2017 IPR000421 Coagulation factor 5/8 C-terminal domain SMD11_RS18380 7fca4d3a13018d7f29da356e9240dde6 207 Pfam PF00578 AhpC/TSA family 64 185 2.6E-19 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMD11_RS18380 7fca4d3a13018d7f29da356e9240dde6 207 SUPERFAMILY SSF52833 63 206 1.04E-32 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS18380 7fca4d3a13018d7f29da356e9240dde6 207 Gene3D G3DSA:3.40.30.10 15 206 5.6E-44 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS15875 f82e32aeedcb0438f149251b042974f1 318 SUPERFAMILY SSF51197 26 317 1.01E-37 T 06-07-2017 SMD11_RS15875 f82e32aeedcb0438f149251b042974f1 318 PIRSF PIRSF019543 4 318 6.9E-32 T 06-07-2017 IPR014503 Clavaminate synthase GO:0005506|GO:0017000|GO:0033758|GO:0055114 SMD11_RS15875 f82e32aeedcb0438f149251b042974f1 318 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 172 316 4.5E-11 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMD11_RS15875 f82e32aeedcb0438f149251b042974f1 318 Gene3D G3DSA:3.60.130.10 54 317 8.5E-37 T 06-07-2017 SMD11_RS26820 5880c1ea7b51f11abbe43721f2b03ece 180 TIGRFAM TIGR01529 argR_whole: arginine repressor 22 175 6.0E-42 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMD11_RS26820 5880c1ea7b51f11abbe43721f2b03ece 180 SUPERFAMILY SSF46785 18 86 9.53E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26820 5880c1ea7b51f11abbe43721f2b03ece 180 SUPERFAMILY SSF55252 109 174 6.41E-19 T 06-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SMD11_RS26820 5880c1ea7b51f11abbe43721f2b03ece 180 Pfam PF02863 Arginine repressor, C-terminal domain 109 172 1.3E-23 T 06-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SMD11_RS26820 5880c1ea7b51f11abbe43721f2b03ece 180 Pfam PF01316 Arginine repressor, DNA binding domain 19 86 7.5E-25 T 06-07-2017 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 SMD11_RS26820 5880c1ea7b51f11abbe43721f2b03ece 180 Hamap MF_00173 Arginine repressor [argR]. 1 179 56.229 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMD11_RS26820 5880c1ea7b51f11abbe43721f2b03ece 180 Gene3D G3DSA:1.10.10.10 16 89 1.1E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26820 5880c1ea7b51f11abbe43721f2b03ece 180 PRINTS PR01467 Bacterial arginine repressor signature 54 69 2.2E-26 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMD11_RS26820 5880c1ea7b51f11abbe43721f2b03ece 180 PRINTS PR01467 Bacterial arginine repressor signature 115 128 2.2E-26 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMD11_RS26820 5880c1ea7b51f11abbe43721f2b03ece 180 PRINTS PR01467 Bacterial arginine repressor signature 38 51 2.2E-26 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMD11_RS26820 5880c1ea7b51f11abbe43721f2b03ece 180 PRINTS PR01467 Bacterial arginine repressor signature 145 160 2.2E-26 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 SMD11_RS26820 5880c1ea7b51f11abbe43721f2b03ece 180 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 117 169 4.0E-12 T 06-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SMD11_RS26820 5880c1ea7b51f11abbe43721f2b03ece 180 Gene3D G3DSA:3.30.1360.40 100 175 7.3E-28 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain SMD11_RS20725 d8f1e82ed875e9385d5dce67b60e1b81 387 Gene3D G3DSA:3.40.50.10490 236 384 7.5E-5 T 06-07-2017 SMD11_RS20725 d8f1e82ed875e9385d5dce67b60e1b81 387 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 237 384 2.9E-22 T 06-07-2017 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 SMD11_RS20725 d8f1e82ed875e9385d5dce67b60e1b81 387 SUPERFAMILY SSF53697 67 384 5.78E-42 T 06-07-2017 SMD11_RS10815 90af7515c1a8134929b4da23458ddaad 269 ProSitePatterns PS00449 ATP synthase a subunit signature. 193 202 - T 06-07-2017 IPR023011 ATPase, F0 complex, subunit A, active site Reactome: R-HSA-163210 SMD11_RS10815 90af7515c1a8134929b4da23458ddaad 269 Gene3D G3DSA:1.20.120.220 97 268 3.0E-38 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 SMD11_RS10815 90af7515c1a8134929b4da23458ddaad 269 Hamap MF_01393 ATP synthase subunit a [atpB]. 34 268 12.998 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 SMD11_RS10815 90af7515c1a8134929b4da23458ddaad 269 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 30 263 7.4E-41 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 SMD11_RS10815 90af7515c1a8134929b4da23458ddaad 269 Pfam PF00119 ATP synthase A chain 47 261 2.2E-48 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 SMD11_RS10815 90af7515c1a8134929b4da23458ddaad 269 SUPERFAMILY SSF81336 97 261 4.71E-34 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 SMD11_RS10815 90af7515c1a8134929b4da23458ddaad 269 PRINTS PR00123 ATP synthase A subunit signature 190 212 4.6E-16 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 SMD11_RS10815 90af7515c1a8134929b4da23458ddaad 269 PRINTS PR00123 ATP synthase A subunit signature 248 263 4.6E-16 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 SMD11_RS10815 90af7515c1a8134929b4da23458ddaad 269 PRINTS PR00123 ATP synthase A subunit signature 105 121 4.6E-16 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 SMD11_RS20520 9c4db5928ab412903a0e77477bad21d2 167 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 39 153 2.7E-26 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD11_RS20520 9c4db5928ab412903a0e77477bad21d2 167 Pfam PF04075 Domain of unknown function (DUF385) 29 152 7.0E-30 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD11_RS20520 9c4db5928ab412903a0e77477bad21d2 167 SUPERFAMILY SSF50475 42 144 4.49E-8 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS20520 9c4db5928ab412903a0e77477bad21d2 167 Gene3D G3DSA:2.30.110.10 46 133 9.9E-9 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS05325 28515c3c8c9c732ad03ef1052a152deb 667 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 35 656 4.3E-241 T 06-07-2017 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 SMD11_RS05325 28515c3c8c9c732ad03ef1052a152deb 667 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 44 654 6.8E-185 T 06-07-2017 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 SMD11_RS05325 28515c3c8c9c732ad03ef1052a152deb 667 SUPERFAMILY SSF48239 327 656 6.28E-106 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS05325 28515c3c8c9c732ad03ef1052a152deb 667 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 340 655 1.5E-139 T 06-07-2017 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 SMD11_RS05325 28515c3c8c9c732ad03ef1052a152deb 667 SUPERFAMILY SSF48239 68 334 1.65E-74 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS05325 28515c3c8c9c732ad03ef1052a152deb 667 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 45 330 1.2E-122 T 06-07-2017 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 SMD11_RS05325 28515c3c8c9c732ad03ef1052a152deb 667 Gene3D G3DSA:1.50.10.20 325 654 1.5E-115 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS05325 28515c3c8c9c732ad03ef1052a152deb 667 Gene3D G3DSA:1.50.10.20 67 324 9.0E-69 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS22415 5e21465d5340ab3cc4f0d5859d6124e3 717 SUPERFAMILY SSF56601 214 459 4.47E-84 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS22415 5e21465d5340ab3cc4f0d5859d6124e3 717 SUPERFAMILY SSF56601 516 666 4.47E-84 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS22415 5e21465d5340ab3cc4f0d5859d6124e3 717 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 247 2.6E-35 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SMD11_RS22415 5e21465d5340ab3cc4f0d5859d6124e3 717 Gene3D G3DSA:3.40.710.10 511 661 1.8E-91 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS22415 5e21465d5340ab3cc4f0d5859d6124e3 717 Gene3D G3DSA:3.40.710.10 262 473 1.8E-91 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS22415 5e21465d5340ab3cc4f0d5859d6124e3 717 Gene3D G3DSA:3.90.1310.10 137 260 6.3E-30 T 06-07-2017 SMD11_RS22415 5e21465d5340ab3cc4f0d5859d6124e3 717 Pfam PF00905 Penicillin binding protein transpeptidase domain 299 657 2.1E-84 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD11_RS22415 5e21465d5340ab3cc4f0d5859d6124e3 717 SUPERFAMILY SSF56519 52 262 1.07E-34 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SMD11_RS22415 5e21465d5340ab3cc4f0d5859d6124e3 717 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 16 661 2.8E-180 T 06-07-2017 IPR017790 Penicillin-binding protein 2 GO:0016020 SMD11_RS11005 c3629275a1406f97678b602737ed5dc5 161 SMART SM00347 52 148 5.8E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS11005 c3629275a1406f97678b602737ed5dc5 161 Pfam PF01047 MarR family 59 114 7.4E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS11005 c3629275a1406f97678b602737ed5dc5 161 Gene3D G3DSA:1.10.10.10 30 159 3.0E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11005 c3629275a1406f97678b602737ed5dc5 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 90 3.2E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS11005 c3629275a1406f97678b602737ed5dc5 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 126 3.2E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS11005 c3629275a1406f97678b602737ed5dc5 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 106 3.2E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS11005 c3629275a1406f97678b602737ed5dc5 161 SUPERFAMILY SSF46785 30 158 1.82E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS34225 5a13e3ba442e84bfcac42ccee3862bf2 265 Gene3D G3DSA:3.30.1380.10 22 199 2.4E-34 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 SMD11_RS34225 5a13e3ba442e84bfcac42ccee3862bf2 265 Pfam PF01427 D-ala-D-ala dipeptidase 66 205 1.3E-16 T 06-07-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMD11_RS34225 5a13e3ba442e84bfcac42ccee3862bf2 265 SUPERFAMILY SSF55166 23 199 5.49E-32 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 SMD11_RS21110 0a2d0bbd9f38955a09fdc001beb405bc 481 SUPERFAMILY SSF103473 30 220 1.44E-36 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS21110 0a2d0bbd9f38955a09fdc001beb405bc 481 SUPERFAMILY SSF103473 263 479 1.44E-36 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS21110 0a2d0bbd9f38955a09fdc001beb405bc 481 Gene3D G3DSA:1.20.1250.20 64 218 1.1E-20 T 06-07-2017 SMD11_RS21110 0a2d0bbd9f38955a09fdc001beb405bc 481 Pfam PF07690 Major Facilitator Superfamily 44 332 5.8E-23 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS21110 0a2d0bbd9f38955a09fdc001beb405bc 481 Gene3D G3DSA:1.20.1250.20 284 478 8.3E-9 T 06-07-2017 SMD11_RS07205 2efe4a9682739e0e92e5b02bb8808a61 177 Gene3D G3DSA:3.40.50.300 2 176 7.0E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07205 2efe4a9682739e0e92e5b02bb8808a61 177 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 3 166 8.5E-59 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 SMD11_RS07205 2efe4a9682739e0e92e5b02bb8808a61 177 Pfam PF01583 Adenylylsulphate kinase 3 157 5.2E-60 T 06-07-2017 SMD11_RS07205 2efe4a9682739e0e92e5b02bb8808a61 177 SUPERFAMILY SSF52540 2 174 7.45E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07205 2efe4a9682739e0e92e5b02bb8808a61 177 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 1 175 34.06 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 SMD11_RS27325 9920946c8cfcd1f0df80f7b036099ebe 188 Hamap MF_00141 Elongation factor P [efp]. 1 186 50.621 T 06-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 SMD11_RS27325 9920946c8cfcd1f0df80f7b036099ebe 188 SMART SM00841 130 185 4.4E-32 T 06-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 SMD11_RS27325 9920946c8cfcd1f0df80f7b036099ebe 188 PIRSF PIRSF005901 1 187 2.5E-65 T 06-07-2017 IPR020599 Translation elongation factor P/YeiP SMD11_RS27325 9920946c8cfcd1f0df80f7b036099ebe 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 122 7.6E-20 T 06-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 SMD11_RS27325 9920946c8cfcd1f0df80f7b036099ebe 188 Pfam PF09285 Elongation factor P, C-terminal 130 185 2.1E-25 T 06-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 SMD11_RS27325 9920946c8cfcd1f0df80f7b036099ebe 188 Gene3D G3DSA:2.40.50.140 130 186 1.0E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS27325 9920946c8cfcd1f0df80f7b036099ebe 188 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 06-07-2017 IPR013852 Translation elongation factor P/YeiP, conserved site SMD11_RS27325 9920946c8cfcd1f0df80f7b036099ebe 188 Gene3D G3DSA:2.40.50.140 66 128 2.5E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS27325 9920946c8cfcd1f0df80f7b036099ebe 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 61 6.7E-26 T 06-07-2017 IPR013185 Translation elongation factor, KOW-like SMD11_RS27325 9920946c8cfcd1f0df80f7b036099ebe 188 SMART SM01185 68 122 3.8E-24 T 06-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 SMD11_RS27325 9920946c8cfcd1f0df80f7b036099ebe 188 TIGRFAM TIGR00038 efp: translation elongation factor P 3 186 1.2E-74 T 06-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 SMD11_RS27325 9920946c8cfcd1f0df80f7b036099ebe 188 SUPERFAMILY SSF50249 66 127 2.87E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS27325 9920946c8cfcd1f0df80f7b036099ebe 188 SUPERFAMILY SSF50249 130 186 1.06E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS27325 9920946c8cfcd1f0df80f7b036099ebe 188 SUPERFAMILY SSF50104 2 64 9.63E-19 T 06-07-2017 IPR008991 Translation protein SH3-like domain SMD11_RS27325 9920946c8cfcd1f0df80f7b036099ebe 188 Gene3D G3DSA:2.30.30.30 3 64 7.0E-31 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 SMD11_RS18520 678cea180e3d42507c68c160d25147a5 427 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 11 333 9.7E-89 T 06-07-2017 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 SMD11_RS18520 678cea180e3d42507c68c160d25147a5 427 SUPERFAMILY SSF51905 288 381 4.58E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18520 678cea180e3d42507c68c160d25147a5 427 SUPERFAMILY SSF51905 7 192 4.58E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18520 678cea180e3d42507c68c160d25147a5 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 161 176 1.2E-10 T 06-07-2017 SMD11_RS18520 678cea180e3d42507c68c160d25147a5 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 1.2E-10 T 06-07-2017 SMD11_RS18520 678cea180e3d42507c68c160d25147a5 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 313 1.2E-10 T 06-07-2017 SMD11_RS18520 678cea180e3d42507c68c160d25147a5 427 Gene3D G3DSA:3.30.9.10 176 342 5.2E-52 T 06-07-2017 SMD11_RS18520 678cea180e3d42507c68c160d25147a5 427 Gene3D G3DSA:3.50.50.60 6 175 5.9E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18520 678cea180e3d42507c68c160d25147a5 427 Pfam PF01494 FAD binding domain 10 187 3.7E-13 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS17040 30bc62a003e40e6214a11856ce3cb154 485 SUPERFAMILY SSF56601 139 482 1.55E-85 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS17040 30bc62a003e40e6214a11856ce3cb154 485 Pfam PF00905 Penicillin binding protein transpeptidase domain 156 478 2.9E-71 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD11_RS17040 30bc62a003e40e6214a11856ce3cb154 485 Gene3D G3DSA:3.40.710.10 144 483 3.5E-93 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS17040 30bc62a003e40e6214a11856ce3cb154 485 Gene3D G3DSA:3.90.1310.10 73 143 4.3E-6 T 06-07-2017 SMD11_RS22705 fed91e0d80803bccc51d1f020732a0eb 829 Gene3D G3DSA:2.130.10.80 238 630 1.4E-57 T 06-07-2017 IPR015916 Galactose oxidase, beta-propeller SMD11_RS22705 fed91e0d80803bccc51d1f020732a0eb 829 SUPERFAMILY SSF50965 284 626 3.27E-30 T 06-07-2017 IPR011043 Galactose oxidase/kelch, beta-propeller SMD11_RS22705 fed91e0d80803bccc51d1f020732a0eb 829 SUPERFAMILY SSF81296 626 726 1.54E-25 T 06-07-2017 IPR014756 Immunoglobulin E-set SMD11_RS22705 fed91e0d80803bccc51d1f020732a0eb 829 Pfam PF09118 Domain of unknown function (DUF1929) 630 724 1.1E-22 T 06-07-2017 IPR015202 Domain of unknown function DUF1929 SMD11_RS22705 fed91e0d80803bccc51d1f020732a0eb 829 Gene3D G3DSA:2.60.120.260 61 224 4.7E-9 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS22705 fed91e0d80803bccc51d1f020732a0eb 829 Pfam PF07250 Glyoxal oxidase N-terminus 281 477 8.1E-12 T 06-07-2017 IPR009880 Glyoxal oxidase, N-terminal SMD11_RS22705 fed91e0d80803bccc51d1f020732a0eb 829 Gene3D G3DSA:2.60.40.10 631 725 9.6E-30 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS10140 6b6d5cce8ac362ad188c57dfbb00e473 707 Pfam PF00990 Diguanylate cyclase, GGDEF domain 252 404 1.1E-40 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS10140 6b6d5cce8ac362ad188c57dfbb00e473 707 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 250 404 1.4E-34 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS10140 6b6d5cce8ac362ad188c57dfbb00e473 707 SUPERFAMILY SSF55073 255 406 9.42E-44 T 06-07-2017 IPR029787 Nucleotide cyclase SMD11_RS10140 6b6d5cce8ac362ad188c57dfbb00e473 707 SMART SM00052 420 664 8.1E-102 T 06-07-2017 IPR001633 EAL domain SMD11_RS10140 6b6d5cce8ac362ad188c57dfbb00e473 707 SMART SM00267 244 410 4.1E-50 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS10140 6b6d5cce8ac362ad188c57dfbb00e473 707 Gene3D G3DSA:3.30.70.270 252 412 3.0E-50 T 06-07-2017 SMD11_RS10140 6b6d5cce8ac362ad188c57dfbb00e473 707 Gene3D G3DSA:3.20.20.450 426 670 3.6E-91 T 06-07-2017 IPR001633 EAL domain SMD11_RS10140 6b6d5cce8ac362ad188c57dfbb00e473 707 SUPERFAMILY SSF141868 426 670 1.57E-82 T 06-07-2017 IPR001633 EAL domain SMD11_RS10140 6b6d5cce8ac362ad188c57dfbb00e473 707 Pfam PF00563 EAL domain 427 657 9.5E-70 T 06-07-2017 IPR001633 EAL domain SMD11_RS09295 dc25620459b0104bd2b9b356bd71720d 433 Pfam PF13180 PDZ domain 182 237 7.1E-8 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS09295 dc25620459b0104bd2b9b356bd71720d 433 Pfam PF02163 Peptidase family M50 13 386 1.8E-47 T 06-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 SMD11_RS09295 dc25620459b0104bd2b9b356bd71720d 433 Gene3D G3DSA:2.30.42.10 122 237 1.5E-22 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS09295 dc25620459b0104bd2b9b356bd71720d 433 SUPERFAMILY SSF50156 128 237 2.37E-17 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS09295 dc25620459b0104bd2b9b356bd71720d 433 SMART SM00228 149 230 3.7E-4 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS14555 52e147509f22a355ff9fd7fbcd0c0945 330 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 33 325 2.1E-86 T 06-07-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 SMD11_RS14555 52e147509f22a355ff9fd7fbcd0c0945 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 324 3.7E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS14555 52e147509f22a355ff9fd7fbcd0c0945 330 SUPERFAMILY SSF161098 46 316 1.28E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS14555 52e147509f22a355ff9fd7fbcd0c0945 330 Gene3D G3DSA:1.10.3720.10 44 328 6.5E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS20950 2624952eabaa3d11100ce05e43088f3a 426 SMART SM00245 219 408 8.8E-39 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMD11_RS20950 2624952eabaa3d11100ce05e43088f3a 426 SMART SM00228 123 219 1.1E-7 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS20950 2624952eabaa3d11100ce05e43088f3a 426 Gene3D G3DSA:2.30.42.10 126 228 6.4E-17 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS20950 2624952eabaa3d11100ce05e43088f3a 426 SUPERFAMILY SSF52096 220 408 3.81E-45 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS20950 2624952eabaa3d11100ce05e43088f3a 426 SUPERFAMILY SSF52096 83 118 3.81E-45 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS20950 2624952eabaa3d11100ce05e43088f3a 426 Pfam PF03572 Peptidase family S41 253 407 3.6E-38 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMD11_RS20950 2624952eabaa3d11100ce05e43088f3a 426 Gene3D G3DSA:3.90.226.10 229 410 1.0E-44 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS20950 2624952eabaa3d11100ce05e43088f3a 426 SUPERFAMILY SSF50156 102 183 1.31E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS20950 2624952eabaa3d11100ce05e43088f3a 426 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 122 183 1.5E-10 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 SUPERFAMILY SSF52540 919 1157 4.04E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 604 1119 3.9E-196 T 06-07-2017 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 SUPERFAMILY SSF90123 596 911 2.75E-43 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 Gene3D G3DSA:3.40.50.300 925 1161 2.5E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 Gene3D G3DSA:1.20.1560.10 601 908 4.6E-33 T 06-07-2017 SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 Gene3D G3DSA:1.20.1560.10 6 321 5.9E-53 T 06-07-2017 SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 Pfam PF00005 ABC transporter 354 501 9.1E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 Pfam PF00005 ABC transporter 940 1088 8.1E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 Pfam PF00664 ABC transporter transmembrane region 648 860 2.8E-6 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 Pfam PF00664 ABC transporter transmembrane region 20 274 3.7E-33 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 ProSitePatterns PS00211 ABC transporters family signature. 1061 1075 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 SUPERFAMILY SSF90123 1 326 8.5E-61 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 16 543 5.3E-216 T 06-07-2017 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 SMART SM00382 949 1135 6.1E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 SMART SM00382 361 547 5.6E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 SUPERFAMILY SSF52540 331 545 7.76E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16550 bf69bac4aa26d284b45460dfc1b1a822 1211 Gene3D G3DSA:3.40.50.300 334 543 1.3E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24660 115945ad03b28c66972fedfdcb29ffc6 165 PIRSF PIRSF006181 7 165 2.8E-51 T 06-07-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC SMD11_RS24660 115945ad03b28c66972fedfdcb29ffc6 165 Pfam PF04073 Aminoacyl-tRNA editing domain 35 152 2.3E-26 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD11_RS24660 115945ad03b28c66972fedfdcb29ffc6 165 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 12 162 7.6E-53 T 06-07-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC SMD11_RS24660 115945ad03b28c66972fedfdcb29ffc6 165 SUPERFAMILY SSF55826 12 162 1.02E-42 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD11_RS24660 115945ad03b28c66972fedfdcb29ffc6 165 Gene3D G3DSA:3.90.960.10 6 164 2.0E-58 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 Pfam PF00512 His Kinase A (phospho-acceptor) domain 618 685 1.2E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 SUPERFAMILY SSF52402 232 348 2.33E-8 T 06-07-2017 SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 Gene3D G3DSA:1.20.120.620 380 479 3.2E-20 T 06-07-2017 SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 Gene3D G3DSA:3.30.565.10 672 833 8.4E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 Pfam PF00582 Universal stress protein family 232 346 3.1E-5 T 06-07-2017 IPR006016 UspA GO:0006950 SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 Gene3D G3DSA:3.40.50.300 2 210 1.1E-100 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 PRINTS PR00344 Bacterial sensor protein C-terminal signature 762 776 2.6E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 PRINTS PR00344 Bacterial sensor protein C-terminal signature 795 813 2.6E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 PRINTS PR00344 Bacterial sensor protein C-terminal signature 819 832 2.6E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 PRINTS PR00344 Bacterial sensor protein C-terminal signature 780 790 2.6E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 Gene3D G3DSA:1.10.287.130 608 671 2.0E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 3 211 7.9E-101 T 06-07-2017 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 SUPERFAMILY SSF55874 675 831 1.7E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 SMART SM00388 617 685 5.0E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 726 833 1.8E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 Gene3D G3DSA:3.40.50.620 227 346 3.3E-10 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 Pfam PF13493 Domain of unknown function (DUF4118) 383 488 1.7E-26 T 06-07-2017 IPR025201 Sensor protein KdpD, transmembrane domain SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 SMART SM00387 725 835 5.1E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08485 feda04e7cc1c511d5e64651d20314caa 850 SUPERFAMILY SSF47384 607 685 1.57E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS05335 81a5c549bb3db8a9ad6d6259368a24b7 486 Gene3D G3DSA:3.50.50.60 26 78 7.2E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05335 81a5c549bb3db8a9ad6d6259368a24b7 486 Gene3D G3DSA:3.50.50.60 441 475 7.2E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05335 81a5c549bb3db8a9ad6d6259368a24b7 486 Gene3D G3DSA:3.50.50.60 238 337 7.2E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05335 81a5c549bb3db8a9ad6d6259368a24b7 486 SUPERFAMILY SSF51905 431 473 1.66E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05335 81a5c549bb3db8a9ad6d6259368a24b7 486 SUPERFAMILY SSF51905 21 339 1.66E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05335 81a5c549bb3db8a9ad6d6259368a24b7 486 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 27 471 2.8E-136 T 06-07-2017 IPR017830 Squalene-associated FAD-dependent desaturase SMD11_RS05335 81a5c549bb3db8a9ad6d6259368a24b7 486 Pfam PF01593 Flavin containing amine oxidoreductase 33 470 1.8E-46 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD11_RS05335 81a5c549bb3db8a9ad6d6259368a24b7 486 PRINTS PR00757 Flavin-containing amine oxidase signature 183 204 1.4E-7 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMD11_RS05335 81a5c549bb3db8a9ad6d6259368a24b7 486 PRINTS PR00757 Flavin-containing amine oxidase signature 25 44 1.4E-7 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMD11_RS05335 81a5c549bb3db8a9ad6d6259368a24b7 486 PRINTS PR00757 Flavin-containing amine oxidase signature 452 469 1.4E-7 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 SMD11_RS11615 99548f95e23b1bb87183c428ba008504 921 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 642 916 2.8E-15 T 06-07-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD SMD11_RS11615 99548f95e23b1bb87183c428ba008504 921 SUPERFAMILY SSF56112 358 457 2.64E-7 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS11615 99548f95e23b1bb87183c428ba008504 921 Gene3D G3DSA:1.10.510.10 391 457 8.2E-5 T 06-07-2017 SMD11_RS11615 99548f95e23b1bb87183c428ba008504 921 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 622 908 2.5E-33 T 06-07-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD SMD11_RS25775 c4ad73067e3c221b45059e327a6d0c5f 372 Pfam PF13579 Glycosyl transferase 4-like domain 26 170 4.0E-20 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 SMD11_RS25775 c4ad73067e3c221b45059e327a6d0c5f 372 SUPERFAMILY SSF53756 25 369 1.53E-62 T 06-07-2017 SMD11_RS25775 c4ad73067e3c221b45059e327a6d0c5f 372 Gene3D G3DSA:3.40.50.2000 182 345 5.7E-25 T 06-07-2017 SMD11_RS25775 c4ad73067e3c221b45059e327a6d0c5f 372 Pfam PF00534 Glycosyl transferases group 1 196 344 2.0E-24 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 SMD11_RS10290 dd5e0827edd29ab744ac5f605a442e58 125 SUPERFAMILY SSF51230 4 123 3.53E-39 T 06-07-2017 IPR011053 Single hybrid motif SMD11_RS10290 dd5e0827edd29ab744ac5f605a442e58 125 Pfam PF01597 Glycine cleavage H-protein 7 122 4.4E-42 T 06-07-2017 IPR002930 Glycine cleavage system H-protein SMD11_RS10290 dd5e0827edd29ab744ac5f605a442e58 125 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 123 1.2E-45 T 06-07-2017 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 SMD11_RS10290 dd5e0827edd29ab744ac5f605a442e58 125 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 124 29.367 T 06-07-2017 IPR002930 Glycine cleavage system H-protein SMD11_RS10290 dd5e0827edd29ab744ac5f605a442e58 125 Gene3D G3DSA:2.40.50.100 6 123 4.3E-45 T 06-07-2017 SMD11_RS10290 dd5e0827edd29ab744ac5f605a442e58 125 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 48 77 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SMD11_RS17655 70dab32e743a3bcb3a4dd57083885e98 305 SUPERFAMILY SSF46955 7 111 2.27E-22 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS17655 70dab32e743a3bcb3a4dd57083885e98 305 Gene3D G3DSA:1.10.1660.10 8 117 6.0E-27 T 06-07-2017 SMD11_RS17655 70dab32e743a3bcb3a4dd57083885e98 305 SMART SM00422 7 76 1.2E-23 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS17655 70dab32e743a3bcb3a4dd57083885e98 305 Pfam PF13411 MerR HTH family regulatory protein 8 75 1.0E-16 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS17655 70dab32e743a3bcb3a4dd57083885e98 305 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 9.4E-12 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS17655 70dab32e743a3bcb3a4dd57083885e98 305 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 9.4E-12 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS17655 70dab32e743a3bcb3a4dd57083885e98 305 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 9.4E-12 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 SMART SM00028 933 966 0.0034 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 SMART SM00028 813 846 81.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 SMART SM00028 893 926 370.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 SMART SM00028 853 886 4.9 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 SUPERFAMILY SSF52540 291 543 1.96E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 Gene3D G3DSA:3.40.50.300 304 414 7.2E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 SUPERFAMILY SSF48452 758 965 7.59E-21 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 Pfam PF13424 Tetratricopeptide repeat 815 884 1.9E-11 T 06-07-2017 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 Pfam PF13424 Tetratricopeptide repeat 896 964 5.9E-8 T 06-07-2017 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 SMART SM01043 122 266 1.5E-47 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 SUPERFAMILY SSF46894 22 115 7.94E-12 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 Pfam PF00486 Transcriptional regulatory protein, C terminal 44 114 3.1E-7 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 Gene3D G3DSA:1.25.40.10 785 968 1.6E-22 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 SUPERFAMILY SSF48452 117 282 1.04E-29 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 SMART SM00862 37 115 2.1E-6 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 Pfam PF00931 NB-ARC domain 307 494 3.5E-11 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 PRINTS PR00364 Disease resistance protein signature 398 412 9.3E-9 T 06-07-2017 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 PRINTS PR00364 Disease resistance protein signature 321 336 9.3E-9 T 06-07-2017 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 PRINTS PR00364 Disease resistance protein signature 483 497 9.3E-9 T 06-07-2017 SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 Pfam PF03704 Bacterial transcriptional activator domain 122 266 1.2E-42 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS06820 1eede33e93a94d4b7acbdf9f6451796d 981 Gene3D G3DSA:1.10.10.10 43 117 1.2E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08955 a160a17f790deb9bbc9bf7aed61e911a 380 Pfam PF01594 Domain of unknown function DUF20 43 363 1.4E-75 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like SMD11_RS21525 0f28e0f3735cac6c909a77708289d184 674 SUPERFAMILY SSF50965 265 547 5.23E-29 T 06-07-2017 IPR011043 Galactose oxidase/kelch, beta-propeller SMD11_RS21525 0f28e0f3735cac6c909a77708289d184 674 Gene3D G3DSA:2.130.10.80 63 139 6.0E-62 T 06-07-2017 IPR015916 Galactose oxidase, beta-propeller SMD11_RS21525 0f28e0f3735cac6c909a77708289d184 674 Gene3D G3DSA:2.130.10.80 260 552 6.0E-62 T 06-07-2017 IPR015916 Galactose oxidase, beta-propeller SMD11_RS21525 0f28e0f3735cac6c909a77708289d184 674 SUPERFAMILY SSF81296 549 647 3.5E-20 T 06-07-2017 IPR014756 Immunoglobulin E-set SMD11_RS21525 0f28e0f3735cac6c909a77708289d184 674 Gene3D G3DSA:2.60.40.10 553 647 1.1E-25 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS21525 0f28e0f3735cac6c909a77708289d184 674 SUPERFAMILY SSF50965 55 142 1.44E-5 T 06-07-2017 IPR011043 Galactose oxidase/kelch, beta-propeller SMD11_RS21525 0f28e0f3735cac6c909a77708289d184 674 Pfam PF09118 Domain of unknown function (DUF1929) 552 647 1.4E-21 T 06-07-2017 IPR015202 Domain of unknown function DUF1929 SMD11_RS04645 a6502f4943b14486d60918a9b54a923c 332 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 115 192 1.4E-25 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS04645 a6502f4943b14486d60918a9b54a923c 332 SUPERFAMILY SSF53901 11 331 1.87E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS04645 a6502f4943b14486d60918a9b54a923c 332 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 13 330 6.4E-99 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS04645 a6502f4943b14486d60918a9b54a923c 332 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 11 331 55.647 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS04645 a6502f4943b14486d60918a9b54a923c 332 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 241 330 8.1E-31 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS04645 a6502f4943b14486d60918a9b54a923c 332 Gene3D G3DSA:3.40.47.10 10 170 6.0E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS04645 a6502f4943b14486d60918a9b54a923c 332 Gene3D G3DSA:3.40.47.10 171 330 7.6E-44 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.366.10 6920 7044 3.8E-80 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.366.10 765 894 2.7E-74 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.366.10 7110 7230 3.8E-80 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.366.10 560 696 2.7E-74 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF14765 Polyketide synthase dehydratase 949 1221 2.2E-55 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF52151 4056 4152 4.97E-67 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF52151 3863 3992 4.97E-67 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1961 1977 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4802 4817 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.47.10 4865 5129 2.5E-91 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.47.10 1797 2060 8.8E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF47336 4772 4883 1.83E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF08990 Erythronolide synthase docking 3 27 3.9E-9 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF55048 2456 2520 1.18E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.47.10 8168 8329 1.8E-61 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.47.10 285 450 1.1E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.47.10 5130 5297 3.4E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.47.10 3594 3759 1.6E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.47.10 6673 6838 2.4E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.47.10 2061 2226 1.8E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM01294 3244 3311 1.4E-4 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM01294 7816 7883 5.8E-5 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM01294 4776 4843 5.6E-4 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM01294 6323 6390 6.9E-7 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM01294 9346 9413 2.3E-6 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM01294 1710 1777 4.9E-7 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00825 Beta-ketoacyl synthase 7912 8331 8.9E-202 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00825 Beta-ketoacyl synthase 6418 6836 9.0E-209 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00825 Beta-ketoacyl synthase 4870 5295 5.4E-216 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00825 Beta-ketoacyl synthase 3337 3759 2.8E-216 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00825 Beta-ketoacyl synthase 36 450 1.4E-208 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00825 Beta-ketoacyl synthase 1802 2226 3.0E-222 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF52151 5399 5531 1.15E-73 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF52151 5595 5697 1.15E-73 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.47.10 6418 6672 1.9E-91 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.47.10 3337 3593 2.3E-91 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.47.10 7912 8167 7.0E-86 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.47.10 36 284 2.6E-88 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF47336 1705 1815 4.32E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3270 3285 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1736 1751 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF53901 3334 3703 6.18E-104 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF52151 2325 2457 2.38E-70 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF52151 2521 2620 2.38E-70 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.366.10 2323 2451 2.3E-73 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.366.10 3857 3986 1.1E-73 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.366.10 8430 8556 7.0E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.366.10 5396 5525 6.4E-80 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.366.10 5594 5705 6.4E-80 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.366.10 2520 2631 2.3E-73 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.366.10 8622 8735 7.0E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.366.10 4055 4168 1.1E-73 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF51735 2962 3192 6.11E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3867 4165 1.6E-120 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2329 2629 6.3E-121 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 8439 8732 2.6E-126 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5403 5703 9.1E-130 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 573 881 5.8E-121 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6926 7216 9.5E-131 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF55048 8561 8622 1.07E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF51735 2742 2949 6.5E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF51735 7536 7762 1.28E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF55048 3991 4055 3.4E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.30.70.250 5529 5593 1.9E-9 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.30.70.250 3990 4054 3.8E-5 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.30.70.250 2456 2519 6.3E-7 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.30.70.250 700 764 3.7E-9 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.30.70.250 8561 8621 3.2E-8 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.30.70.250 7048 7109 1.9E-7 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 ProSitePatterns PS00012 Phosphopantetheine attachment site. 7842 7857 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:1.10.1200.10 6320 6394 1.4E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:1.10.1200.10 9343 9416 3.6E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:1.10.1200.10 4773 4849 3.5E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:1.10.1200.10 7812 7887 2.3E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:1.10.1200.10 3241 3316 1.2E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:1.10.1200.10 1706 1781 6.0E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF53901 30 394 1.83E-95 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF51735 6034 6265 1.29E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF51735 1229 1416 1.91E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF52151 8435 8562 1.91E-72 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF52151 8623 8725 1.91E-72 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 8068 8084 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF53901 4865 5233 2.73E-102 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF51735 4488 4743 4.96E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF52151 569 701 2.2E-69 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF52151 765 861 2.2E-69 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 272 2.6E-80 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1800 2048 1.4E-91 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7910 8155 1.1E-82 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3335 3581 2.2E-89 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4868 5117 4.9E-93 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6416 6660 1.9E-86 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF51735 1423 1661 1.3E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF51735 9061 9293 9.12E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 6573 6589 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.50.720 7539 7748 1.2E-7 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF08659 KR domain 4493 4672 1.3E-57 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF08659 KR domain 6036 6214 1.3E-61 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF08659 KR domain 7538 7710 2.3E-19 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF08659 KR domain 9062 9239 4.5E-58 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF08659 KR domain 1427 1604 9.0E-57 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF08659 KR domain 2963 3141 3.5E-60 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF52151 7110 7209 1.73E-74 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF52151 6922 7049 1.73E-74 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF47336 9338 9423 2.22E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 185 201 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF55048 700 764 2.62E-13 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF51735 4273 4479 1.42E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF47336 7809 7925 1.16E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3494 3510 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF55048 5530 5594 3.92E-13 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 ProSitePatterns PS00012 Phosphopantetheine attachment site. 9372 9387 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF51735 7325 7526 7.31E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2963 3142 9.1E-55 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9062 9241 2.4E-56 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7538 7711 7.9E-9 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6036 6215 1.3E-58 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4493 4673 7.5E-51 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1427 1628 6.3E-58 T 06-07-2017 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.50.720 1427 1629 2.6E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.50.720 9062 9275 2.6E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.50.720 6036 6250 8.9E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.50.720 2962 3176 4.2E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Gene3D G3DSA:3.40.50.720 4493 4700 7.5E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 280 397 2.1E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3589 3706 7.6E-44 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2056 2173 6.0E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5125 5242 2.0E-42 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 6669 6783 4.7E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 8163 8278 1.5E-44 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF55048 7048 7109 3.53E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00826 949 1111 2.4E-87 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5030 5046 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF47336 3241 3350 1.57E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 6786 6874 4.1E-11 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3709 3830 1.3E-10 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5245 5367 1.6E-16 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 400 533 6.6E-13 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 8281 8400 1.6E-11 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2176 2289 6.0E-16 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF53901 6413 6781 6.24E-101 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF53901 1797 2170 2.75E-104 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00550 Phosphopantetheine attachment site 7817 7883 1.6E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00550 Phosphopantetheine attachment site 4777 4843 8.5E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00550 Phosphopantetheine attachment site 1712 1777 2.8E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00550 Phosphopantetheine attachment site 3245 3311 6.9E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00550 Phosphopantetheine attachment site 9347 9413 1.5E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00550 Phosphopantetheine attachment site 6324 6390 1.7E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF53901 7908 8275 4.59E-102 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF47336 6316 6431 1.96E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6349 6364 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00698 Acyl transferase domain 3865 4183 1.2E-87 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00698 Acyl transferase domain 2329 2648 1.1E-55 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00698 Acyl transferase domain 8439 8752 3.8E-63 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00698 Acyl transferase domain 5402 5722 7.6E-57 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00698 Acyl transferase domain 572 900 1.3E-54 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 Pfam PF00698 Acyl transferase domain 6926 7235 1.4E-64 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF51735 5813 6022 3.58E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00823 Phosphopantetheine attachment site 6322 6394 1.4E-30 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00823 Phosphopantetheine attachment site 3243 3315 4.8E-29 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00823 Phosphopantetheine attachment site 7815 7887 3.5E-30 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00823 Phosphopantetheine attachment site 9345 9417 5.3E-33 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00823 Phosphopantetheine attachment site 1709 1781 1.1E-32 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SMART SM00823 Phosphopantetheine attachment site 4775 4847 3.6E-25 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32315 4188f479157f1c5d31bc5b0a31e5fb9b 9507 SUPERFAMILY SSF51735 8842 9047 1.61E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS11045 b0d403bbfbe36e6d5e7b30dd13509d26 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 336 349 3.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS11045 b0d403bbfbe36e6d5e7b30dd13509d26 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 276 290 3.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS11045 b0d403bbfbe36e6d5e7b30dd13509d26 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 294 304 3.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS11045 b0d403bbfbe36e6d5e7b30dd13509d26 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 331 3.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS11045 b0d403bbfbe36e6d5e7b30dd13509d26 356 SUPERFAMILY SSF47384 103 184 9.61E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS11045 b0d403bbfbe36e6d5e7b30dd13509d26 356 SMART SM00388 120 184 1.7E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS11045 b0d403bbfbe36e6d5e7b30dd13509d26 356 Gene3D G3DSA:3.30.565.10 171 352 1.1E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS11045 b0d403bbfbe36e6d5e7b30dd13509d26 356 Pfam PF00672 HAMP domain 49 115 7.4E-16 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS11045 b0d403bbfbe36e6d5e7b30dd13509d26 356 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 238 350 3.9E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS11045 b0d403bbfbe36e6d5e7b30dd13509d26 356 SMART SM00304 67 119 7.5E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS11045 b0d403bbfbe36e6d5e7b30dd13509d26 356 Gene3D G3DSA:1.10.287.130 110 170 5.8E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS11045 b0d403bbfbe36e6d5e7b30dd13509d26 356 SMART SM00387 237 352 1.6E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS11045 b0d403bbfbe36e6d5e7b30dd13509d26 356 Pfam PF00512 His Kinase A (phospho-acceptor) domain 121 184 4.3E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS11045 b0d403bbfbe36e6d5e7b30dd13509d26 356 SUPERFAMILY SSF55874 173 350 8.12E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS11045 b0d403bbfbe36e6d5e7b30dd13509d26 356 SUPERFAMILY SSF158472 69 115 2.22E-11 T 06-07-2017 SMD11_RS19790 2d81245216f33365be08a46edec46ed8 259 SUPERFAMILY SSF53335 87 245 1.94E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS19790 2d81245216f33365be08a46edec46ed8 259 Gene3D G3DSA:3.40.50.150 64 247 2.4E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS19790 2d81245216f33365be08a46edec46ed8 259 Pfam PF08242 Methyltransferase domain 99 200 1.4E-14 T 06-07-2017 IPR013217 Methyltransferase type 12 SMD11_RS22885 6432675d98c87387a98ac9569242a01e 327 PRINTS PR00691 Adhesin B signature 70 88 1.5E-8 T 06-07-2017 IPR006129 Adhesin B GO:0007155 SMD11_RS22885 6432675d98c87387a98ac9569242a01e 327 PRINTS PR00691 Adhesin B signature 303 321 1.5E-8 T 06-07-2017 IPR006129 Adhesin B GO:0007155 SMD11_RS22885 6432675d98c87387a98ac9569242a01e 327 PRINTS PR00691 Adhesin B signature 156 175 1.5E-8 T 06-07-2017 IPR006129 Adhesin B GO:0007155 SMD11_RS22885 6432675d98c87387a98ac9569242a01e 327 PRINTS PR00691 Adhesin B signature 45 66 1.5E-8 T 06-07-2017 IPR006129 Adhesin B GO:0007155 SMD11_RS22885 6432675d98c87387a98ac9569242a01e 327 SUPERFAMILY SSF53807 27 325 8.34E-74 T 06-07-2017 SMD11_RS22885 6432675d98c87387a98ac9569242a01e 327 Gene3D G3DSA:3.40.50.1980 207 325 1.2E-32 T 06-07-2017 SMD11_RS22885 6432675d98c87387a98ac9569242a01e 327 PRINTS PR00690 Adhesin family signature 265 283 8.6E-6 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 SMD11_RS22885 6432675d98c87387a98ac9569242a01e 327 PRINTS PR00690 Adhesin family signature 76 89 8.6E-6 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 SMD11_RS22885 6432675d98c87387a98ac9569242a01e 327 PRINTS PR00690 Adhesin family signature 45 63 8.6E-6 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 SMD11_RS22885 6432675d98c87387a98ac9569242a01e 327 PRINTS PR00690 Adhesin family signature 212 233 8.6E-6 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 SMD11_RS22885 6432675d98c87387a98ac9569242a01e 327 Gene3D G3DSA:3.40.50.1980 31 206 4.4E-45 T 06-07-2017 SMD11_RS22885 6432675d98c87387a98ac9569242a01e 327 Pfam PF01297 Zinc-uptake complex component A periplasmic 48 323 4.0E-69 T 06-07-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 SMD11_RS20225 dc253fe51d1abc7df14e8bd0c1657de5 857 Pfam PF02687 FtsX-like permease family 734 849 1.7E-19 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 SMD11_RS20225 dc253fe51d1abc7df14e8bd0c1657de5 857 Pfam PF02687 FtsX-like permease family 273 393 7.9E-24 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 SMD11_RS20225 dc253fe51d1abc7df14e8bd0c1657de5 857 Pfam PF12704 MacB-like periplasmic core domain 496 699 2.0E-12 T 06-07-2017 IPR025857 MacB-like periplasmic core domain SMD11_RS20225 dc253fe51d1abc7df14e8bd0c1657de5 857 Pfam PF12704 MacB-like periplasmic core domain 19 234 2.0E-16 T 06-07-2017 IPR025857 MacB-like periplasmic core domain SMD11_RS28420 0bc5392f0b67baee38d4c1e89c796da9 276 SUPERFAMILY SSF49899 28 273 1.41E-14 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain SMD11_RS28420 0bc5392f0b67baee38d4c1e89c796da9 276 Gene3D G3DSA:2.60.120.200 30 275 2.5E-16 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain SMD11_RS28420 0bc5392f0b67baee38d4c1e89c796da9 276 Pfam PF00722 Glycosyl hydrolases family 16 138 236 5.2E-6 T 06-07-2017 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 SMD11_RS12525 2497d13ceab67822ff356fe3b2ac8ae3 151 SMART SM00530 37 92 2.2E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS12525 2497d13ceab67822ff356fe3b2ac8ae3 151 SUPERFAMILY SSF47413 28 98 5.93E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS12525 2497d13ceab67822ff356fe3b2ac8ae3 151 Pfam PF01381 Helix-turn-helix 38 92 3.1E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS12525 2497d13ceab67822ff356fe3b2ac8ae3 151 Gene3D G3DSA:1.10.260.40 34 100 1.8E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS34405 f22267701098617c13adef2a3a752e2e 440 Pfam PF13581 Histidine kinase-like ATPase domain 39 142 4.5E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS34405 f22267701098617c13adef2a3a752e2e 440 SUPERFAMILY SSF55874 62 159 8.51E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS34405 f22267701098617c13adef2a3a752e2e 440 SUPERFAMILY SSF51197 200 423 1.37E-25 T 06-07-2017 SMD11_RS34405 f22267701098617c13adef2a3a752e2e 440 Gene3D G3DSA:3.30.565.10 42 155 4.4E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS34405 f22267701098617c13adef2a3a752e2e 440 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 204 421 6.0E-16 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMD11_RS34405 f22267701098617c13adef2a3a752e2e 440 Gene3D G3DSA:3.60.130.10 273 416 1.7E-20 T 06-07-2017 SMD11_RS23140 af75148c231de6b7d91b9558a6b79bfa 216 Gene3D G3DSA:2.40.440.10 97 209 3.3E-13 T 06-07-2017 SMD11_RS23140 af75148c231de6b7d91b9558a6b79bfa 216 Pfam PF03734 L,D-transpeptidase catalytic domain 99 209 2.1E-13 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMD11_RS23140 af75148c231de6b7d91b9558a6b79bfa 216 SUPERFAMILY SSF141523 99 209 7.72E-23 T 06-07-2017 SMD11_RS33035 8e9086368a5bd1875553ff2f4d02f19d 174 Gene3D G3DSA:1.10.10.10 16 167 1.0E-38 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33035 8e9086368a5bd1875553ff2f4d02f19d 174 SUPERFAMILY SSF46785 18 167 4.92E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33035 8e9086368a5bd1875553ff2f4d02f19d 174 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 108 2.0E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS33035 8e9086368a5bd1875553ff2f4d02f19d 174 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 128 2.0E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS33035 8e9086368a5bd1875553ff2f4d02f19d 174 PRINTS PR00598 Bacterial regulatory protein MarR family signature 142 162 2.0E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS33035 8e9086368a5bd1875553ff2f4d02f19d 174 ProSitePatterns PS01117 MarR-type HTH domain signature. 91 125 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site SMD11_RS33035 8e9086368a5bd1875553ff2f4d02f19d 174 SMART SM00347 49 152 3.2E-20 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS33035 8e9086368a5bd1875553ff2f4d02f19d 174 Pfam PF12802 MarR family 56 116 2.3E-12 T 06-07-2017 SMD11_RS15910 669833251e4bcdcea81a2ef6fbd34d55 335 SMART SM00829 10 321 5.9E-13 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS15910 669833251e4bcdcea81a2ef6fbd34d55 335 SUPERFAMILY SSF51735 119 292 3.12E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS15910 669833251e4bcdcea81a2ef6fbd34d55 335 Pfam PF00107 Zinc-binding dehydrogenase 157 273 7.3E-19 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS15910 669833251e4bcdcea81a2ef6fbd34d55 335 SUPERFAMILY SSF50129 1 145 1.03E-34 T 06-07-2017 IPR011032 GroES-like SMD11_RS15910 669833251e4bcdcea81a2ef6fbd34d55 335 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 3.8E-9 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS15910 669833251e4bcdcea81a2ef6fbd34d55 335 Gene3D G3DSA:3.90.180.10 1 149 1.1E-33 T 06-07-2017 IPR011032 GroES-like SMD11_RS15910 669833251e4bcdcea81a2ef6fbd34d55 335 Gene3D G3DSA:3.40.50.720 150 264 1.1E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10480 312f113e41f8e6cba8d3483d83e69386 554 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 62 111 1.6E-17 T 06-07-2017 IPR011096 FTP domain SMD11_RS10480 312f113e41f8e6cba8d3483d83e69386 554 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 378 552 1.8E-47 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 SMD11_RS10480 312f113e41f8e6cba8d3483d83e69386 554 Gene3D G3DSA:3.10.170.10 227 378 5.0E-45 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS10480 312f113e41f8e6cba8d3483d83e69386 554 Gene3D G3DSA:1.10.390.10 380 552 8.9E-48 T 06-07-2017 SMD11_RS10480 312f113e41f8e6cba8d3483d83e69386 554 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 228 375 2.3E-46 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS10480 312f113e41f8e6cba8d3483d83e69386 554 SUPERFAMILY SSF55486 226 552 2.01E-75 T 06-07-2017 SMD11_RS10480 312f113e41f8e6cba8d3483d83e69386 554 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 330 350 1.2E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS10480 312f113e41f8e6cba8d3483d83e69386 554 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 454 470 1.2E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS10480 312f113e41f8e6cba8d3483d83e69386 554 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 366 382 1.2E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS10480 312f113e41f8e6cba8d3483d83e69386 554 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 387 398 1.2E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS26135 e01befb30fb846b2482c98757dabdab9 271 SUPERFAMILY SSF53448 28 246 3.94E-37 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS26135 e01befb30fb846b2482c98757dabdab9 271 Gene3D G3DSA:3.90.550.10 30 144 1.8E-14 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS26135 e01befb30fb846b2482c98757dabdab9 271 Pfam PF00535 Glycosyl transferase family 2 33 154 8.6E-19 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD11_RS13110 51a7586ffdd9035becc1675452d13de9 337 Pfam PF00579 tRNA synthetases class I (W and Y) 5 283 3.3E-78 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS13110 51a7586ffdd9035becc1675452d13de9 337 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 5 333 41.936 T 06-07-2017 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 SMD11_RS13110 51a7586ffdd9035becc1675452d13de9 337 SUPERFAMILY SSF52374 7 332 6.0E-98 T 06-07-2017 SMD11_RS13110 51a7586ffdd9035becc1675452d13de9 337 Gene3D G3DSA:1.10.240.10 210 300 2.6E-19 T 06-07-2017 SMD11_RS13110 51a7586ffdd9035becc1675452d13de9 337 Gene3D G3DSA:3.40.50.620 6 209 8.9E-84 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS13110 51a7586ffdd9035becc1675452d13de9 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 146 167 8.3E-27 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMD11_RS13110 51a7586ffdd9035becc1675452d13de9 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 19 35 8.3E-27 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMD11_RS13110 51a7586ffdd9035becc1675452d13de9 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 8.3E-27 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMD11_RS13110 51a7586ffdd9035becc1675452d13de9 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 199 209 8.3E-27 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMD11_RS13110 51a7586ffdd9035becc1675452d13de9 337 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 5 332 6.2E-107 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMD11_RS13110 51a7586ffdd9035becc1675452d13de9 337 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 14 24 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 ProSitePatterns PS00455 Putative AMP-binding domain signature. 608 619 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF56801 423 984 1.14E-153 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:3.40.50.980 3714 3877 6.0E-45 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:3.40.50.980 1494 1659 1.0E-51 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF13745 HxxPF-repeated domain 3572 3668 1.1E-30 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF13745 HxxPF-repeated domain 4628 4713 5.4E-6 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF47336 3158 3229 2.22E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF47336 2000 2069 1.57E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 ProSitePatterns PS00012 Phosphopantetheine attachment site. 995 1010 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF52777 16 188 1.02E-32 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF00501 AMP-binding enzyme 1500 1904 1.4E-102 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF00501 AMP-binding enzyme 2630 3052 2.4E-90 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF00501 AMP-binding enzyme 463 858 2.2E-95 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF00501 AMP-binding enzyme 3721 4120 3.0E-88 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3190 3205 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF56801 1464 2020 3.14E-161 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:3.30.559.10 1051 1210 9.4E-4 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF52777 2173 2348 3.45E-38 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:2.30.38.10 1816 1894 4.4E-27 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:2.30.38.10 4031 4109 1.7E-27 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:2.30.38.10 770 848 9.6E-26 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:2.30.38.10 2965 3041 5.2E-26 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF13193 AMP-binding enzyme C-terminal domain 4128 4202 5.4E-14 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF13193 AMP-binding enzyme C-terminal domain 1912 1982 8.5E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF13193 AMP-binding enzyme C-terminal domain 3060 3140 2.6E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF13193 AMP-binding enzyme C-terminal domain 866 946 1.7E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2786 2797 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF52777 1224 1469 8.0E-52 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF52777 3254 3426 6.45E-45 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF47336 4222 4293 4.84E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3867 3878 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF52777 4313 4506 2.22E-32 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF52777 1054 1238 3.78E-40 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF56801 3681 4239 2.62E-149 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SMART SM00823 Phosphopantetheine attachment site 3165 3235 1.7E-5 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SMART SM00823 Phosphopantetheine attachment site 2007 2075 0.005 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SMART SM00823 Phosphopantetheine attachment site 4227 4296 5.6E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SMART SM00823 Phosphopantetheine attachment site 971 1039 2.7E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 484 882 3.9E-128 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1521 1928 3.2E-138 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2650 3076 9.6E-112 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3742 4144 2.4E-128 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF52777 2354 2593 4.89E-48 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF00550 Phosphopantetheine attachment site 3167 3230 7.1E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF00550 Phosphopantetheine attachment site 4229 4290 1.7E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF00550 Phosphopantetheine attachment site 973 1034 1.1E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF00550 Phosphopantetheine attachment site 2009 2069 8.9E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4251 4266 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:3.40.50.980 458 613 2.8E-52 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:3.40.50.980 2623 2800 6.2E-42 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1638 1649 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF52777 4494 4730 1.11E-47 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF52777 3439 3685 6.45E-61 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF56801 2594 3178 1.96E-138 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:1.10.1200.10 2011 2069 1.9E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:1.10.1200.10 4233 4296 3.0E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:1.10.1200.10 3168 3232 1.3E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:1.10.1200.10 977 1035 3.7E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:3.30.300.30 4116 4232 1.8E-35 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:3.30.300.30 854 976 4.7E-34 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:3.30.300.30 3047 3167 3.3E-34 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:3.30.300.30 1900 2010 4.8E-32 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:3.40.50.980 3878 4030 1.5E-33 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:3.40.50.980 614 769 5.5E-36 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF47336 965 1033 9.95E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 SUPERFAMILY SSF52777 191 427 3.11E-42 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF00668 Condensation domain 3251 3550 4.3E-60 T 06-07-2017 IPR001242 Condensation domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF00668 Condensation domain 12 301 6.0E-45 T 06-07-2017 IPR001242 Condensation domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF00668 Condensation domain 1055 1341 4.5E-55 T 06-07-2017 IPR001242 Condensation domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF00668 Condensation domain 4315 4605 6.9E-36 T 06-07-2017 IPR001242 Condensation domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Pfam PF00668 Condensation domain 2168 2464 1.5E-50 T 06-07-2017 IPR001242 Condensation domain SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:3.40.50.980 1660 1815 1.5E-43 T 06-07-2017 SMD11_RS31205 8f6116a033d03f23ad7cf048dad7fbc9 4738 Gene3D G3DSA:3.40.50.980 2828 2964 3.8E-28 T 06-07-2017 SMD11_RS28550 6abab5540865ccb9f35d02dc6fec33a6 208 Gene3D G3DSA:3.30.230.30 5 131 2.3E-45 T 06-07-2017 IPR001498 Impact, N-terminal SMD11_RS28550 6abab5540865ccb9f35d02dc6fec33a6 208 Pfam PF01205 Uncharacterized protein family UPF0029 20 124 1.9E-29 T 06-07-2017 IPR001498 Impact, N-terminal SMD11_RS28550 6abab5540865ccb9f35d02dc6fec33a6 208 SUPERFAMILY SSF54211 2 130 5.31E-41 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS28550 6abab5540865ccb9f35d02dc6fec33a6 208 Pfam PF09186 Domain of unknown function (DUF1949) 140 194 4.0E-13 T 06-07-2017 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal SMD11_RS28550 6abab5540865ccb9f35d02dc6fec33a6 208 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 06-07-2017 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site SMD11_RS28550 6abab5540865ccb9f35d02dc6fec33a6 208 Gene3D G3DSA:3.30.70.240 138 205 2.0E-12 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain SMD11_RS28550 6abab5540865ccb9f35d02dc6fec33a6 208 SUPERFAMILY SSF54980 138 198 5.04E-16 T 06-07-2017 IPR009022 Elongation factor G, III-V domain SMD11_RS28550 6abab5540865ccb9f35d02dc6fec33a6 208 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 199 3.6E-58 T 06-07-2017 IPR015796 Impact family, bacterial/archaeal SMD11_RS05755 22193fa609496ddea856bd8b77261b2e 285 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 275 34.238 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 SMD11_RS05755 22193fa609496ddea856bd8b77261b2e 285 SUPERFAMILY SSF53927 4 275 1.86E-78 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 SMD11_RS05755 22193fa609496ddea856bd8b77261b2e 285 PIRSF PIRSF015626 1 278 1.3E-89 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 SMD11_RS05755 22193fa609496ddea856bd8b77261b2e 285 Gene3D G3DSA:3.10.20.10 28 120 7.1E-27 T 06-07-2017 SMD11_RS05755 22193fa609496ddea856bd8b77261b2e 285 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 274 8.6E-49 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 SMD11_RS05755 22193fa609496ddea856bd8b77261b2e 285 Gene3D G3DSA:3.40.140.10 139 277 1.7E-55 T 06-07-2017 SMD11_RS05755 22193fa609496ddea856bd8b77261b2e 285 Pfam PF02634 FdhD/NarQ family 26 274 9.2E-82 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 SMD11_RS00945 94465e5db4f0036bbf41e1ee89f61861 558 SUPERFAMILY SSF56601 245 553 5.63E-57 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS00945 94465e5db4f0036bbf41e1ee89f61861 558 Pfam PF00905 Penicillin binding protein transpeptidase domain 283 550 2.5E-39 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD11_RS00945 94465e5db4f0036bbf41e1ee89f61861 558 Gene3D G3DSA:3.40.710.10 260 553 6.5E-59 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS00945 94465e5db4f0036bbf41e1ee89f61861 558 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 72 179 4.0E-21 T 06-07-2017 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 SMD11_RS02935 e536bb60afbc5cfe6659575ee096662b 138 PRINTS PR00332 Histidine triad family signature 93 103 8.4E-10 T 06-07-2017 IPR001310 Histidine triad (HIT) protein SMD11_RS02935 e536bb60afbc5cfe6659575ee096662b 138 PRINTS PR00332 Histidine triad family signature 7 23 8.4E-10 T 06-07-2017 IPR001310 Histidine triad (HIT) protein SMD11_RS02935 e536bb60afbc5cfe6659575ee096662b 138 PRINTS PR00332 Histidine triad family signature 28 46 8.4E-10 T 06-07-2017 IPR001310 Histidine triad (HIT) protein SMD11_RS02935 e536bb60afbc5cfe6659575ee096662b 138 Gene3D G3DSA:3.30.428.10 5 138 8.3E-34 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 SMD11_RS02935 e536bb60afbc5cfe6659575ee096662b 138 SUPERFAMILY SSF54197 5 138 2.78E-33 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 SMD11_RS02935 e536bb60afbc5cfe6659575ee096662b 138 Pfam PF01230 HIT domain 15 107 5.2E-18 T 06-07-2017 IPR001310 Histidine triad (HIT) protein SMD11_RS13510 c3ef7baee12abc05446de36878d0ac0f 364 Gene3D G3DSA:1.25.40.10 252 341 4.8E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS13510 c3ef7baee12abc05446de36878d0ac0f 364 Pfam PF13432 Tetratricopeptide repeat 16 68 0.012 T 06-07-2017 SMD11_RS13510 c3ef7baee12abc05446de36878d0ac0f 364 SUPERFAMILY SSF48452 125 228 9.36E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS13510 c3ef7baee12abc05446de36878d0ac0f 364 SUPERFAMILY SSF48452 277 344 9.36E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS13510 c3ef7baee12abc05446de36878d0ac0f 364 SMART SM00028 34 67 180.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS13510 c3ef7baee12abc05446de36878d0ac0f 364 SMART SM00028 277 310 1.1 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS13510 c3ef7baee12abc05446de36878d0ac0f 364 SMART SM00028 155 188 250.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS13510 c3ef7baee12abc05446de36878d0ac0f 364 SMART SM00028 317 350 21.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS13510 c3ef7baee12abc05446de36878d0ac0f 364 Gene3D G3DSA:1.25.40.10 7 251 6.6E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS06080 d57e7018857e2c5c381ef7e55fe97b22 328 Pfam PF05709 Phage tail protein 64 326 6.1E-14 T 06-07-2017 IPR008841 Siphovirus-type tail component SMD11_RS34235 bc34e10b4efe582f839879292f0b19ea 114 Pfam PF00589 Phage integrase family 7 82 6.4E-9 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS34235 bc34e10b4efe582f839879292f0b19ea 114 Gene3D G3DSA:1.10.443.10 17 97 4.9E-14 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS34235 bc34e10b4efe582f839879292f0b19ea 114 SUPERFAMILY SSF56349 8 100 5.3E-14 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD11_RS14470 cd362021d95b866150642115b1a8006f 423 Hamap MF_01812 UPF0256 protein . 1 423 44.76 T 06-07-2017 IPR022902 Uncharacterised protein family UPF0256 SMD11_RS14470 cd362021d95b866150642115b1a8006f 423 Pfam PF13527 Acetyltransferase (GNAT) domain 4 141 9.2E-24 T 06-07-2017 SMD11_RS14470 cd362021d95b866150642115b1a8006f 423 Gene3D G3DSA:3.40.630.30 148 306 1.1E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS14470 cd362021d95b866150642115b1a8006f 423 SUPERFAMILY SSF55729 4 316 2.35E-52 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS14470 cd362021d95b866150642115b1a8006f 423 Pfam PF13530 Sterol carrier protein domain 193 420 2.9E-44 T 06-07-2017 IPR025559 Enhanced intracellular survival protein domain SMD11_RS14470 cd362021d95b866150642115b1a8006f 423 Gene3D G3DSA:3.30.1050.10 320 410 3.0E-14 T 06-07-2017 IPR003033 SCP2 sterol-binding domain SMD11_RS14470 cd362021d95b866150642115b1a8006f 423 Gene3D G3DSA:3.40.630.30 4 143 6.0E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS14470 cd362021d95b866150642115b1a8006f 423 SUPERFAMILY SSF55718 319 423 5.49E-19 T 06-07-2017 IPR003033 SCP2 sterol-binding domain SMD11_RS07470 b2b27b541e8027ed579288a460dadcd5 406 Pfam PF02803 Thiolase, C-terminal domain 276 397 1.9E-35 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD11_RS07470 b2b27b541e8027ed579288a460dadcd5 406 Pfam PF00108 Thiolase, N-terminal domain 8 266 8.7E-56 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD11_RS07470 b2b27b541e8027ed579288a460dadcd5 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 397 3.4E-126 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS07470 b2b27b541e8027ed579288a460dadcd5 406 Gene3D G3DSA:3.40.47.10 192 278 4.2E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07470 b2b27b541e8027ed579288a460dadcd5 406 Gene3D G3DSA:3.40.47.10 7 131 4.2E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07470 b2b27b541e8027ed579288a460dadcd5 406 Gene3D G3DSA:3.40.47.10 152 191 3.2E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07470 b2b27b541e8027ed579288a460dadcd5 406 Gene3D G3DSA:3.40.47.10 280 398 3.2E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07470 b2b27b541e8027ed579288a460dadcd5 406 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMD11_RS07470 b2b27b541e8027ed579288a460dadcd5 406 PIRSF PIRSF000429 3 400 3.2E-119 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS07470 b2b27b541e8027ed579288a460dadcd5 406 SUPERFAMILY SSF53901 276 397 7.46E-38 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07470 b2b27b541e8027ed579288a460dadcd5 406 SUPERFAMILY SSF53901 7 273 1.15E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS05780 2319ff9938d9404566ba2147440f6ceb 311 SUPERFAMILY SSF53850 88 278 1.85E-28 T 06-07-2017 SMD11_RS05780 2319ff9938d9404566ba2147440f6ceb 311 Gene3D G3DSA:1.10.10.10 3 79 3.2E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05780 2319ff9938d9404566ba2147440f6ceb 311 Pfam PF03466 LysR substrate binding domain 87 276 2.3E-30 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS05780 2319ff9938d9404566ba2147440f6ceb 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 9.4E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS05780 2319ff9938d9404566ba2147440f6ceb 311 Gene3D G3DSA:3.40.190.10 179 242 2.6E-8 T 06-07-2017 SMD11_RS05780 2319ff9938d9404566ba2147440f6ceb 311 Gene3D G3DSA:3.40.190.10 88 178 3.5E-18 T 06-07-2017 SMD11_RS05780 2319ff9938d9404566ba2147440f6ceb 311 SUPERFAMILY SSF46785 2 109 2.18E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05780 2319ff9938d9404566ba2147440f6ceb 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 8.5E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS05780 2319ff9938d9404566ba2147440f6ceb 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 8.5E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS05780 2319ff9938d9404566ba2147440f6ceb 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 8.5E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS34585 50d6c1f0068c47e87a14d338785b24a4 175 SMART SM00860 24 133 5.4E-5 T 06-07-2017 IPR018958 SMI1/KNR4-like domain SMD11_RS34585 50d6c1f0068c47e87a14d338785b24a4 175 SUPERFAMILY SSF160631 24 131 7.85E-6 T 06-07-2017 SMD11_RS34585 50d6c1f0068c47e87a14d338785b24a4 175 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 24 134 4.1E-12 T 06-07-2017 IPR018958 SMI1/KNR4-like domain SMD11_RS05715 2906dcb19f793558d2c4980d2cba203a 451 Gene3D G3DSA:1.25.40.10 218 410 1.6E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS05715 2906dcb19f793558d2c4980d2cba203a 451 SUPERFAMILY SSF48452 208 414 2.6E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS05490 c214d73a64c7eeb80c180a7eee3bb687 386 Pfam PF02515 CoA-transferase family III 14 365 6.2E-88 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 SMD11_RS05490 c214d73a64c7eeb80c180a7eee3bb687 386 Gene3D G3DSA:3.30.1540.10 232 302 3.4E-12 T 06-07-2017 SMD11_RS05490 c214d73a64c7eeb80c180a7eee3bb687 386 Gene3D G3DSA:3.40.50.10540 12 216 4.0E-96 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS05490 c214d73a64c7eeb80c180a7eee3bb687 386 Gene3D G3DSA:3.40.50.10540 303 373 4.0E-96 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS05490 c214d73a64c7eeb80c180a7eee3bb687 386 SUPERFAMILY SSF89796 12 373 1.96E-114 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS14645 6e0f02aa04647413ba78394fc9feb95f 471 Pfam PF12846 AAA-like domain 69 349 1.7E-14 T 06-07-2017 SMD11_RS14645 6e0f02aa04647413ba78394fc9feb95f 471 Gene3D G3DSA:3.40.50.300 73 159 2.1E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14645 6e0f02aa04647413ba78394fc9feb95f 471 Gene3D G3DSA:3.40.50.300 245 375 2.1E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14645 6e0f02aa04647413ba78394fc9feb95f 471 SUPERFAMILY SSF52540 40 424 1.68E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12910 7a17ad63886d125e9294629f959f1c0c 547 Pfam PF01425 Amidase 91 511 9.0E-102 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS12910 7a17ad63886d125e9294629f959f1c0c 547 Gene3D G3DSA:3.90.1300.10 78 527 4.1E-112 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS12910 7a17ad63886d125e9294629f959f1c0c 547 ProSitePatterns PS00571 Amidases signature. 217 248 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMD11_RS12910 7a17ad63886d125e9294629f959f1c0c 547 SUPERFAMILY SSF75304 77 529 2.49E-112 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS01140 03a57a11aba12f582447317bcfae85cd 506 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 399 505 1.9E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS01140 03a57a11aba12f582447317bcfae85cd 506 Gene3D G3DSA:1.10.287.130 287 338 1.4E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS01140 03a57a11aba12f582447317bcfae85cd 506 SUPERFAMILY SSF55874 341 505 6.42E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS01140 03a57a11aba12f582447317bcfae85cd 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 487 7.4E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS01140 03a57a11aba12f582447317bcfae85cd 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 505 7.4E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS01140 03a57a11aba12f582447317bcfae85cd 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 462 7.4E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS01140 03a57a11aba12f582447317bcfae85cd 506 Gene3D G3DSA:3.30.565.10 339 505 2.1E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS01140 03a57a11aba12f582447317bcfae85cd 506 SMART SM00388 290 352 5.5E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS01140 03a57a11aba12f582447317bcfae85cd 506 SMART SM00387 399 506 1.9E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS01140 03a57a11aba12f582447317bcfae85cd 506 Pfam PF00512 His Kinase A (phospho-acceptor) domain 291 351 1.8E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS01140 03a57a11aba12f582447317bcfae85cd 506 SUPERFAMILY SSF47384 273 351 3.34E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS01140 03a57a11aba12f582447317bcfae85cd 506 Pfam PF00672 HAMP domain 218 284 3.6E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS03770 28e34fb8a0a33e015779827cdb1cf57e 179 Pfam PF08002 Protein of unknown function (DUF1697) 2 137 4.3E-43 T 06-07-2017 IPR012545 Protein of unknown function DUF1697 SMD11_RS03770 28e34fb8a0a33e015779827cdb1cf57e 179 SUPERFAMILY SSF160379 2 177 1.31E-54 T 06-07-2017 SMD11_RS03770 28e34fb8a0a33e015779827cdb1cf57e 179 Gene3D G3DSA:3.30.70.1280 2 88 6.9E-27 T 06-07-2017 SMD11_RS03770 28e34fb8a0a33e015779827cdb1cf57e 179 PIRSF PIRSF008502 1 179 4.7E-52 T 06-07-2017 IPR012545 Protein of unknown function DUF1697 SMD11_RS08465 53840480ab3d953c013d0234167dd496 225 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 4.0E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS08465 53840480ab3d953c013d0234167dd496 225 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 4.0E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS08465 53840480ab3d953c013d0234167dd496 225 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 4.0E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS08465 53840480ab3d953c013d0234167dd496 225 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 4.0E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS08465 53840480ab3d953c013d0234167dd496 225 Pfam PF02254 TrkA-N domain 3 118 1.6E-24 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SMD11_RS08465 53840480ab3d953c013d0234167dd496 225 Gene3D G3DSA:3.30.70.1450 147 217 4.6E-12 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD11_RS08465 53840480ab3d953c013d0234167dd496 225 Gene3D G3DSA:3.40.50.720 1 132 4.2E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08465 53840480ab3d953c013d0234167dd496 225 Pfam PF02080 TrkA-C domain 149 216 3.3E-12 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD11_RS08465 53840480ab3d953c013d0234167dd496 225 SUPERFAMILY SSF116726 133 216 2.88E-14 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD11_RS08465 53840480ab3d953c013d0234167dd496 225 SUPERFAMILY SSF51735 1 145 5.15E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32740 b0c39c944609c8b3342564605c0c2e2c 487 Gene3D G3DSA:3.50.50.60 279 318 1.4E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS32740 b0c39c944609c8b3342564605c0c2e2c 487 Gene3D G3DSA:3.50.50.60 2 167 1.4E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS32740 b0c39c944609c8b3342564605c0c2e2c 487 SUPERFAMILY SSF51905 268 360 7.35E-65 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS32740 b0c39c944609c8b3342564605c0c2e2c 487 SUPERFAMILY SSF51905 2 177 7.35E-65 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS32740 b0c39c944609c8b3342564605c0c2e2c 487 Pfam PF01494 FAD binding domain 2 346 3.3E-92 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS32740 b0c39c944609c8b3342564605c0c2e2c 487 Gene3D G3DSA:3.30.9.10 168 274 3.6E-10 T 06-07-2017 SMD11_RS32740 b0c39c944609c8b3342564605c0c2e2c 487 Gene3D G3DSA:3.30.9.10 329 367 3.6E-10 T 06-07-2017 SMD11_RS32740 b0c39c944609c8b3342564605c0c2e2c 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 7.1E-49 T 06-07-2017 SMD11_RS32740 b0c39c944609c8b3342564605c0c2e2c 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 332 7.1E-49 T 06-07-2017 SMD11_RS32740 b0c39c944609c8b3342564605c0c2e2c 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 7.1E-49 T 06-07-2017 SMD11_RS32740 b0c39c944609c8b3342564605c0c2e2c 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 7.1E-49 T 06-07-2017 SMD11_RS32740 b0c39c944609c8b3342564605c0c2e2c 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 7.1E-49 T 06-07-2017 SMD11_RS32740 b0c39c944609c8b3342564605c0c2e2c 487 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 332 348 7.1E-49 T 06-07-2017 SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 SUPERFAMILY SSF55048 662 726 4.71E-12 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 SMART SM00825 Beta-ketoacyl synthase 6 434 3.0E-182 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 Pfam PF00550 Phosphopantetheine attachment site 1242 1300 6.4E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 264 381 5.2E-40 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 Gene3D G3DSA:3.40.47.10 6 269 7.7E-86 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 255 3.6E-80 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 Pfam PF00698 Acyl transferase domain 537 850 1.8E-66 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 385 496 2.6E-18 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 SMART SM00823 Phosphopantetheine attachment site 1226 1304 4.0E-11 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 Gene3D G3DSA:3.30.70.250 661 724 3.3E-8 T 06-07-2017 SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 SUPERFAMILY SSF47336 1240 1316 5.37E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 SUPERFAMILY SSF52151 727 828 2.41E-74 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 SUPERFAMILY SSF52151 534 663 2.41E-74 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 Gene3D G3DSA:3.40.366.10 725 836 3.0E-80 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 Gene3D G3DSA:3.40.366.10 531 657 3.0E-80 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 SUPERFAMILY SSF53901 3 124 2.81E-94 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 SUPERFAMILY SSF53901 152 371 2.81E-94 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 Pfam PF14765 Polyketide synthase dehydratase 917 1181 4.8E-43 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 538 832 2.3E-116 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 SMART SM00826 900 1064 7.3E-6 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 Gene3D G3DSA:3.40.47.10 270 433 5.0E-61 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS33590 45a09431d1e13bdb2821304413760ac3 1319 Gene3D G3DSA:1.10.1200.10 1240 1303 6.4E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS07285 bb706d5e3f1204a5b67844706ebb44de 708 SUPERFAMILY SSF51011 595 705 2.88E-24 T 06-07-2017 SMD11_RS07285 bb706d5e3f1204a5b67844706ebb44de 708 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 705 5.5E-295 T 06-07-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 SMD11_RS07285 bb706d5e3f1204a5b67844706ebb44de 708 Pfam PF00128 Alpha amylase, catalytic domain 189 276 3.9E-7 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS07285 bb706d5e3f1204a5b67844706ebb44de 708 SUPERFAMILY SSF51445 499 580 4.4E-129 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS07285 bb706d5e3f1204a5b67844706ebb44de 708 SUPERFAMILY SSF51445 133 470 4.4E-129 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS07285 bb706d5e3f1204a5b67844706ebb44de 708 SUPERFAMILY SSF81296 5 147 5.88E-44 T 06-07-2017 IPR014756 Immunoglobulin E-set SMD11_RS07285 bb706d5e3f1204a5b67844706ebb44de 708 Gene3D G3DSA:2.60.40.10 5 151 9.9E-54 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS07285 bb706d5e3f1204a5b67844706ebb44de 708 Gene3D G3DSA:3.20.20.80 152 580 1.2E-115 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS07285 bb706d5e3f1204a5b67844706ebb44de 708 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 5.1E-16 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 SMD11_RS07285 bb706d5e3f1204a5b67844706ebb44de 708 SMART SM00642 177 572 2.7E-7 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS07285 bb706d5e3f1204a5b67844706ebb44de 708 Gene3D G3DSA:2.60.40.1180 594 706 2.5E-33 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta SMD11_RS32640 62962855d17dab28c828b245422f8415 295 SUPERFAMILY SSF56214 66 150 5.23E-12 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS32640 62962855d17dab28c828b245422f8415 295 SUPERFAMILY SSF56214 155 247 6.98E-11 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS32640 62962855d17dab28c828b245422f8415 295 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 157 234 7.8E-8 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS32640 62962855d17dab28c828b245422f8415 295 Gene3D G3DSA:3.90.470.20 65 166 2.4E-15 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS32640 62962855d17dab28c828b245422f8415 295 Gene3D G3DSA:3.90.470.20 167 225 1.1E-7 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS09515 b0381fa931847bb4c5b386500a425dfb 278 SUPERFAMILY SSF54713 151 277 6.41E-38 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD11_RS09515 b0381fa931847bb4c5b386500a425dfb 278 Gene3D G3DSA:3.30.479.20 242 277 1.2E-23 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD11_RS09515 b0381fa931847bb4c5b386500a425dfb 278 Gene3D G3DSA:3.30.479.20 152 193 1.2E-23 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD11_RS09515 b0381fa931847bb4c5b386500a425dfb 278 SUPERFAMILY SSF54713 57 147 9.81E-18 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD11_RS09515 b0381fa931847bb4c5b386500a425dfb 278 Hamap MF_00050 Elongation factor Ts [tsf]. 1 278 63.95 T 06-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD11_RS09515 b0381fa931847bb4c5b386500a425dfb 278 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 06-07-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD11_RS09515 b0381fa931847bb4c5b386500a425dfb 278 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 277 1.1E-70 T 06-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD11_RS09515 b0381fa931847bb4c5b386500a425dfb 278 Gene3D G3DSA:3.30.479.20 57 150 7.9E-20 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD11_RS09515 b0381fa931847bb4c5b386500a425dfb 278 Pfam PF00889 Elongation factor TS 73 277 1.2E-60 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD11_RS09515 b0381fa931847bb4c5b386500a425dfb 278 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 06-07-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD11_RS09515 b0381fa931847bb4c5b386500a425dfb 278 Gene3D G3DSA:1.10.8.10 3 55 8.8E-24 T 06-07-2017 SMD11_RS09515 b0381fa931847bb4c5b386500a425dfb 278 SUPERFAMILY SSF46934 5 55 2.04E-15 T 06-07-2017 IPR009060 UBA-like GO:0005515 SMD11_RS09515 b0381fa931847bb4c5b386500a425dfb 278 Gene3D G3DSA:1.10.286.20 198 241 3.8E-18 T 06-07-2017 SMD11_RS10810 b658a7b1ed13e4ca46a57b6fafa79ae2 83 Gene3D G3DSA:1.20.20.10 21 79 1.4E-19 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 SMD11_RS10810 b658a7b1ed13e4ca46a57b6fafa79ae2 83 ProSitePatterns PS00605 ATP synthase c subunit signature. 46 67 - T 06-07-2017 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 SMD11_RS10810 b658a7b1ed13e4ca46a57b6fafa79ae2 83 Hamap MF_01396 ATP synthase subunit c [atpH]. 6 83 14.005 T 06-07-2017 SMD11_RS10810 b658a7b1ed13e4ca46a57b6fafa79ae2 83 SUPERFAMILY SSF81333 21 80 9.02E-16 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SMD11_RS10810 b658a7b1ed13e4ca46a57b6fafa79ae2 83 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 26 76 3.0E-12 T 06-07-2017 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SMD11_RS10810 b658a7b1ed13e4ca46a57b6fafa79ae2 83 PRINTS PR00124 ATP synthase C subunit signature 18 37 7.2E-17 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 SMD11_RS10810 b658a7b1ed13e4ca46a57b6fafa79ae2 83 PRINTS PR00124 ATP synthase C subunit signature 39 54 7.2E-17 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 SMD11_RS10810 b658a7b1ed13e4ca46a57b6fafa79ae2 83 PRINTS PR00124 ATP synthase C subunit signature 56 81 7.2E-17 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 SMD11_RS10810 b658a7b1ed13e4ca46a57b6fafa79ae2 83 Pfam PF00137 ATP synthase subunit C 23 77 4.7E-11 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 SUPERFAMILY SSF81660 467 597 1.24E-22 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 Pfam PF00702 haloacid dehalogenase-like hydrolase 451 676 1.8E-44 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 Pfam PF00122 E1-E2 ATPase 228 446 1.9E-64 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 Pfam PF00403 Heavy-metal-associated domain 24 82 1.1E-13 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 SUPERFAMILY SSF55008 22 87 2.36E-17 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 SUPERFAMILY SSF56784 453 473 2.34E-54 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 SUPERFAMILY SSF56784 578 762 2.34E-54 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 PRINTS PR00943 Copper-transporting ATPase signature 438 453 3.0E-7 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 PRINTS PR00943 Copper-transporting ATPase signature 696 710 3.0E-7 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 PRINTS PR00943 Copper-transporting ATPase signature 225 244 3.0E-7 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 PRINTS PR00943 Copper-transporting ATPase signature 639 656 3.0E-7 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 PRINTS PR00943 Copper-transporting ATPase signature 378 392 3.0E-7 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 Gene3D G3DSA:3.40.50.1000 590 730 1.9E-52 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 Gene3D G3DSA:3.40.50.1000 426 471 1.9E-52 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 Gene3D G3DSA:3.40.1110.10 472 589 2.8E-18 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 Gene3D G3DSA:3.30.70.100 22 86 2.7E-21 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 ProSitePatterns PS01047 Heavy-metal-associated domain. 26 54 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 SUPERFAMILY SSF81665 356 449 6.54E-12 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 SUPERFAMILY SSF81665 711 739 6.54E-12 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 SUPERFAMILY SSF81665 225 259 6.54E-12 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 Gene3D G3DSA:2.70.150.10 219 356 1.2E-27 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 SUPERFAMILY SSF81653 260 355 1.14E-25 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 457 463 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 609 619 5.2E-23 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 662 681 5.2E-23 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 305 319 5.2E-23 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 685 697 5.2E-23 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 455 469 5.2E-23 T 06-07-2017 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 229 478 7.5E-43 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 567 741 2.4E-40 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 174 764 1.2E-173 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SMD11_RS04700 b0de0bf8b4778a6e2611f755bd5960b6 771 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 219 765 7.4E-147 T 06-07-2017 SMD11_RS22075 444378c497569366597333eb686fba15 342 Gene3D G3DSA:3.40.190.10 184 285 1.3E-19 T 06-07-2017 SMD11_RS22075 444378c497569366597333eb686fba15 342 SMART SM00062 102 328 1.2E-48 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD11_RS22075 444378c497569366597333eb686fba15 342 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 126 139 - T 06-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 SMD11_RS22075 444378c497569366597333eb686fba15 342 SUPERFAMILY SSF53850 37 48 1.15E-50 T 06-07-2017 SMD11_RS22075 444378c497569366597333eb686fba15 342 SUPERFAMILY SSF53850 92 324 1.15E-50 T 06-07-2017 SMD11_RS22075 444378c497569366597333eb686fba15 342 Gene3D G3DSA:3.40.190.10 286 328 1.3E-25 T 06-07-2017 SMD11_RS22075 444378c497569366597333eb686fba15 342 Gene3D G3DSA:3.40.190.10 99 183 1.3E-25 T 06-07-2017 SMD11_RS22075 444378c497569366597333eb686fba15 342 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 103 312 9.5E-47 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD11_RS05515 a1ce19d149429f68caacfdeff99817fc 99 Pfam PF03795 YCII-related domain 1 81 2.8E-14 T 06-07-2017 IPR005545 YCII-related SMD11_RS05515 a1ce19d149429f68caacfdeff99817fc 99 Gene3D G3DSA:3.30.70.1060 13 82 6.8E-8 T 06-07-2017 SMD11_RS05515 a1ce19d149429f68caacfdeff99817fc 99 SUPERFAMILY SSF54909 1 83 1.15E-17 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS18545 25acf7c7575253d5ac986f0a3e113984 258 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 115 237 5.6E-44 T 06-07-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18545 25acf7c7575253d5ac986f0a3e113984 258 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 166 221 3.0E-24 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18545 25acf7c7575253d5ac986f0a3e113984 258 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 117 238 2.5E-41 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18545 25acf7c7575253d5ac986f0a3e113984 258 SUPERFAMILY SSF143243 102 254 4.58E-46 T 06-07-2017 SMD11_RS18545 25acf7c7575253d5ac986f0a3e113984 258 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 89 246 28.162 T 06-07-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS33075 6593f643ad6717236203d66d0f833e6b 411 Gene3D G3DSA:3.40.50.2000 245 383 2.8E-11 T 06-07-2017 SMD11_RS33075 6593f643ad6717236203d66d0f833e6b 411 Gene3D G3DSA:3.40.50.2000 1 244 2.5E-57 T 06-07-2017 SMD11_RS33075 6593f643ad6717236203d66d0f833e6b 411 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 121 2.4E-9 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD11_RS33075 6593f643ad6717236203d66d0f833e6b 411 SUPERFAMILY SSF53756 1 403 3.71E-89 T 06-07-2017 SMD11_RS13590 2b8d6e8a3dac8085350c569e7bc7f851 590 Gene3D G3DSA:3.30.450.40 416 578 2.2E-13 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS13590 2b8d6e8a3dac8085350c569e7bc7f851 590 SUPERFAMILY SSF55785 153 261 2.09E-16 T 06-07-2017 IPR000014 PAS domain SMD11_RS13590 2b8d6e8a3dac8085350c569e7bc7f851 590 SUPERFAMILY SSF55781 485 580 9.03E-8 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS13590 2b8d6e8a3dac8085350c569e7bc7f851 590 Gene3D G3DSA:3.30.450.20 153 264 3.9E-16 T 06-07-2017 SMD11_RS13590 2b8d6e8a3dac8085350c569e7bc7f851 590 SUPERFAMILY SSF55785 268 358 1.1E-7 T 06-07-2017 IPR000014 PAS domain SMD11_RS13590 2b8d6e8a3dac8085350c569e7bc7f851 590 Pfam PF01590 GAF domain 500 576 1.6E-4 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS13590 2b8d6e8a3dac8085350c569e7bc7f851 590 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 153 274 1.6E-10 T 06-07-2017 IPR000014 PAS domain SMD11_RS13590 2b8d6e8a3dac8085350c569e7bc7f851 590 Pfam PF08448 PAS fold 159 266 3.7E-8 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS13590 2b8d6e8a3dac8085350c569e7bc7f851 590 Pfam PF08448 PAS fold 287 400 5.5E-7 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS13590 2b8d6e8a3dac8085350c569e7bc7f851 590 Gene3D G3DSA:3.30.450.20 270 398 2.7E-9 T 06-07-2017 SMD11_RS13590 2b8d6e8a3dac8085350c569e7bc7f851 590 SMART SM00091 153 221 2.1E-5 T 06-07-2017 IPR000014 PAS domain SMD11_RS13590 2b8d6e8a3dac8085350c569e7bc7f851 590 SMART SM00091 277 342 2.0 T 06-07-2017 IPR000014 PAS domain SMD11_RS22890 dd1a512040d105846341af1fb74d57aa 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 403 422 1.5E-50 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD11_RS22890 dd1a512040d105846341af1fb74d57aa 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 317 329 1.5E-50 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD11_RS22890 dd1a512040d105846341af1fb74d57aa 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 1.5E-50 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD11_RS22890 dd1a512040d105846341af1fb74d57aa 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 190 207 1.5E-50 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD11_RS22890 dd1a512040d105846341af1fb74d57aa 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 137 149 1.5E-50 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD11_RS22890 dd1a512040d105846341af1fb74d57aa 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 207 217 1.5E-50 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD11_RS22890 dd1a512040d105846341af1fb74d57aa 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 158 175 1.5E-50 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD11_RS22890 dd1a512040d105846341af1fb74d57aa 460 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 3 458 49.357 T 06-07-2017 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 SMD11_RS22890 dd1a512040d105846341af1fb74d57aa 460 Pfam PF03129 Anticodon binding domain 366 453 1.8E-22 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS22890 dd1a512040d105846341af1fb74d57aa 460 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 6 234 5.8E-80 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD11_RS22890 dd1a512040d105846341af1fb74d57aa 460 SUPERFAMILY SSF52954 353 455 1.96E-33 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS22890 dd1a512040d105846341af1fb74d57aa 460 Gene3D G3DSA:3.30.930.10 7 361 2.7E-142 T 06-07-2017 SMD11_RS22890 dd1a512040d105846341af1fb74d57aa 460 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 157 332 1.8E-8 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS22890 dd1a512040d105846341af1fb74d57aa 460 Gene3D G3DSA:3.40.50.800 362 455 4.5E-40 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS22890 dd1a512040d105846341af1fb74d57aa 460 SUPERFAMILY SSF55681 5 369 9.48E-118 T 06-07-2017 SMD11_RS25690 8a292d1ef98d1202deca258272e43d10 222 Gene3D G3DSA:3.10.300.10 8 206 1.8E-66 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SMD11_RS25690 8a292d1ef98d1202deca258272e43d10 222 SUPERFAMILY SSF50486 8 206 3.92E-60 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 SMD11_RS25690 8a292d1ef98d1202deca258272e43d10 222 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 13 198 1.7E-61 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SMD11_RS25690 8a292d1ef98d1202deca258272e43d10 222 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 12 201 34.076 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SMD11_RS25690 8a292d1ef98d1202deca258272e43d10 222 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 12 201 6.1E-49 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SMD11_RS18275 2ca529cbd0d27a73ac848af3f3a9058f 259 Pfam PF06971 Putative DNA-binding protein N-terminus 16 63 4.3E-19 T 06-07-2017 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 SMD11_RS18275 2ca529cbd0d27a73ac848af3f3a9058f 259 SUPERFAMILY SSF51735 93 214 2.36E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18275 2ca529cbd0d27a73ac848af3f3a9058f 259 Pfam PF02629 CoA binding domain 91 188 3.3E-21 T 06-07-2017 IPR003781 CoA-binding GO:0048037 SMD11_RS18275 2ca529cbd0d27a73ac848af3f3a9058f 259 Gene3D G3DSA:1.10.10.10 15 85 2.6E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS18275 2ca529cbd0d27a73ac848af3f3a9058f 259 SMART SM00881 89 190 3.0E-17 T 06-07-2017 IPR003781 CoA-binding GO:0048037 SMD11_RS18275 2ca529cbd0d27a73ac848af3f3a9058f 259 Gene3D G3DSA:3.40.50.720 88 221 2.7E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18275 2ca529cbd0d27a73ac848af3f3a9058f 259 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 11 219 36.657 T 06-07-2017 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 SMD11_RS18275 2ca529cbd0d27a73ac848af3f3a9058f 259 SUPERFAMILY SSF46785 17 89 2.15E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00525 064331e59bbbec03f7128de042b95c1c 419 SUPERFAMILY SSF55874 300 415 1.31E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS00525 064331e59bbbec03f7128de042b95c1c 419 Gene3D G3DSA:3.30.565.10 331 417 5.9E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS00525 064331e59bbbec03f7128de042b95c1c 419 Pfam PF07730 Histidine kinase 230 294 6.4E-13 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS09565 fa283d450efb0d10dbac1bf9a80047e8 256 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 137 156 5.3E-20 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09565 fa283d450efb0d10dbac1bf9a80047e8 256 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 89 101 5.3E-20 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09565 fa283d450efb0d10dbac1bf9a80047e8 256 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 39 55 5.3E-20 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09565 fa283d450efb0d10dbac1bf9a80047e8 256 SUPERFAMILY SSF51306 39 189 1.73E-37 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C SMD11_RS09565 fa283d450efb0d10dbac1bf9a80047e8 256 Pfam PF00717 Peptidase S24-like 45 103 2.4E-13 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B SMD11_RS09565 fa283d450efb0d10dbac1bf9a80047e8 256 Gene3D G3DSA:2.10.109.10 137 192 3.5E-29 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain SMD11_RS09565 fa283d450efb0d10dbac1bf9a80047e8 256 Gene3D G3DSA:2.10.109.10 39 99 3.5E-29 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain SMD11_RS09565 fa283d450efb0d10dbac1bf9a80047e8 256 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 26 184 8.9E-37 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09410 4cf45f71254b35547fc3860af872caf3 374 Gene3D G3DSA:3.50.50.60 307 352 6.4E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS09410 4cf45f71254b35547fc3860af872caf3 374 Gene3D G3DSA:3.50.50.60 147 202 6.4E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS09410 4cf45f71254b35547fc3860af872caf3 374 Gene3D G3DSA:3.50.50.60 3 56 6.4E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS09410 4cf45f71254b35547fc3860af872caf3 374 Gene3D G3DSA:3.30.9.10 204 304 2.5E-22 T 06-07-2017 SMD11_RS09410 4cf45f71254b35547fc3860af872caf3 374 Gene3D G3DSA:3.30.9.10 59 146 2.5E-22 T 06-07-2017 SMD11_RS09410 4cf45f71254b35547fc3860af872caf3 374 SUPERFAMILY SSF51905 2 211 1.29E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS09410 4cf45f71254b35547fc3860af872caf3 374 SUPERFAMILY SSF51905 304 354 1.29E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS09410 4cf45f71254b35547fc3860af872caf3 374 Pfam PF01266 FAD dependent oxidoreductase 4 342 2.3E-32 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD11_RS33605 252d440a0a3d567d48d2a982484c38ab 942 SUPERFAMILY SSF56059 121 302 7.46E-16 T 06-07-2017 SMD11_RS33605 252d440a0a3d567d48d2a982484c38ab 942 Gene3D G3DSA:3.40.640.10 558 826 3.4E-84 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS33605 252d440a0a3d567d48d2a982484c38ab 942 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 546 565 1.2E-8 T 06-07-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMD11_RS33605 252d440a0a3d567d48d2a982484c38ab 942 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 812 827 1.2E-8 T 06-07-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMD11_RS33605 252d440a0a3d567d48d2a982484c38ab 942 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 586 605 1.2E-8 T 06-07-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 SMD11_RS33605 252d440a0a3d567d48d2a982484c38ab 942 Gene3D G3DSA:3.90.1150.10 827 940 6.7E-38 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS33605 252d440a0a3d567d48d2a982484c38ab 942 Pfam PF02655 ATP-grasp domain 119 301 1.7E-6 T 06-07-2017 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 SMD11_RS33605 252d440a0a3d567d48d2a982484c38ab 942 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 752 773 - T 06-07-2017 IPR021115 Pyridoxal-phosphate binding site GO:0016831 SMD11_RS33605 252d440a0a3d567d48d2a982484c38ab 942 Gene3D G3DSA:1.20.1340.10 474 554 6.6E-8 T 06-07-2017 SMD11_RS33605 252d440a0a3d567d48d2a982484c38ab 942 SUPERFAMILY SSF53383 474 939 1.57E-111 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS33605 252d440a0a3d567d48d2a982484c38ab 942 Gene3D G3DSA:3.30.470.20 119 302 5.2E-6 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS33605 252d440a0a3d567d48d2a982484c38ab 942 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 507 873 4.9E-54 T 06-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 SMD11_RS08500 ed889c94c120f0a9e11367b5a86dfc52 215 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 9 212 31.84 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SMD11_RS08500 ed889c94c120f0a9e11367b5a86dfc52 215 Pfam PF02669 K+-transporting ATPase, c chain 14 210 6.7E-66 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SMD11_RS08500 ed889c94c120f0a9e11367b5a86dfc52 215 PIRSF PIRSF001296 8 215 1.6E-68 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SMD11_RS08500 ed889c94c120f0a9e11367b5a86dfc52 215 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 14 210 1.8E-48 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 Gene3D G3DSA:3.30.310.50 375 450 6.4E-19 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 379 447 5.5E-12 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 SUPERFAMILY SSF53738 263 369 1.29E-29 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 179 198 6.5E-12 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 6.5E-12 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 6.5E-12 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 Gene3D G3DSA:3.40.120.10 181 255 1.2E-26 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 450 44.434 T 06-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 164 259 7.4E-20 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 Gene3D G3DSA:3.40.120.10 4 159 2.8E-41 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 SUPERFAMILY SSF53738 4 185 1.65E-42 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 SUPERFAMILY SSF53738 163 261 1.81E-28 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 SUPERFAMILY SSF55957 364 452 1.44E-21 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 448 2.5E-173 T 06-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 Gene3D G3DSA:3.40.120.10 256 372 1.8E-33 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 373 3.0E-32 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS19075 ccbcdcdec522ae3c08c1123c9c34ea16 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 138 5.2E-37 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS16315 2f60f6071331bdade8fd7547449d6c4f 217 SMART SM00448 2 115 1.3E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS16315 2f60f6071331bdade8fd7547449d6c4f 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 3.1E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16315 2f60f6071331bdade8fd7547449d6c4f 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 3.1E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16315 2f60f6071331bdade8fd7547449d6c4f 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 3.1E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16315 2f60f6071331bdade8fd7547449d6c4f 217 Gene3D G3DSA:3.40.50.2300 2 155 6.2E-39 T 06-07-2017 SMD11_RS16315 2f60f6071331bdade8fd7547449d6c4f 217 SMART SM00421 153 210 2.5E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16315 2f60f6071331bdade8fd7547449d6c4f 217 Gene3D G3DSA:1.10.10.10 156 215 1.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16315 2f60f6071331bdade8fd7547449d6c4f 217 SUPERFAMILY SSF52172 2 132 3.84E-34 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS16315 2f60f6071331bdade8fd7547449d6c4f 217 SUPERFAMILY SSF46894 145 215 2.07E-19 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS16315 2f60f6071331bdade8fd7547449d6c4f 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 3.2E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16315 2f60f6071331bdade8fd7547449d6c4f 217 Pfam PF00072 Response regulator receiver domain 4 115 1.8E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS09670 8a2a3e40b37c6939ff58fc7006c49f66 1185 Pfam PF06470 SMC proteins Flexible Hinge Domain 513 629 1.9E-21 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SMD11_RS09670 8a2a3e40b37c6939ff58fc7006c49f66 1185 SUPERFAMILY SSF52540 2 207 1.4E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09670 8a2a3e40b37c6939ff58fc7006c49f66 1185 SUPERFAMILY SSF52540 986 1176 1.4E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09670 8a2a3e40b37c6939ff58fc7006c49f66 1185 SMART SM00968 512 629 6.1E-20 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SMD11_RS09670 8a2a3e40b37c6939ff58fc7006c49f66 1185 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1177 7.7E-73 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal SMD11_RS09670 8a2a3e40b37c6939ff58fc7006c49f66 1185 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1184 1.9E-276 T 06-07-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 SMD11_RS09670 8a2a3e40b37c6939ff58fc7006c49f66 1185 SUPERFAMILY SSF75553 495 674 8.11E-24 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SMD11_RS09670 8a2a3e40b37c6939ff58fc7006c49f66 1185 PIRSF PIRSF005719 1 1185 2.0E-257 T 06-07-2017 IPR024704 Structural maintenance of chromosomes protein SMD11_RS09670 8a2a3e40b37c6939ff58fc7006c49f66 1185 Gene3D G3DSA:3.40.50.300 2 163 1.7E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09670 8a2a3e40b37c6939ff58fc7006c49f66 1185 Gene3D G3DSA:3.40.50.300 1033 1180 1.7E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09670 8a2a3e40b37c6939ff58fc7006c49f66 1185 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1185 22.666 T 06-07-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 SMD11_RS31125 a9e5c2776b7763757a9eed496f031666 313 Gene3D G3DSA:2.60.120.280 42 176 3.6E-8 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD11_RS31125 a9e5c2776b7763757a9eed496f031666 313 Pfam PF02311 AraC-like ligand binding domain 47 148 1.9E-5 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD11_RS31125 a9e5c2776b7763757a9eed496f031666 313 SMART SM00342 208 291 7.0E-26 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS31125 a9e5c2776b7763757a9eed496f031666 313 SUPERFAMILY SSF51182 19 126 1.33E-7 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS31125 a9e5c2776b7763757a9eed496f031666 313 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 275 291 2.9E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD11_RS31125 a9e5c2776b7763757a9eed496f031666 313 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 260 275 2.9E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD11_RS31125 a9e5c2776b7763757a9eed496f031666 313 SUPERFAMILY SSF46689 245 295 2.64E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS31125 a9e5c2776b7763757a9eed496f031666 313 Gene3D G3DSA:1.10.10.60 245 293 1.3E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS31125 a9e5c2776b7763757a9eed496f031666 313 Pfam PF12833 Helix-turn-helix domain 214 292 3.4E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS18910 0cd32ce466e68e128ff26680cca1a521 115 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 108 4.6E-45 T 06-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18910 0cd32ce466e68e128ff26680cca1a521 115 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 111 29.829 T 06-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18910 0cd32ce466e68e128ff26680cca1a521 115 ProSitePatterns PS00464 Ribosomal protein L22 signature. 84 108 - T 06-07-2017 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18910 0cd32ce466e68e128ff26680cca1a521 115 Pfam PF00237 Ribosomal protein L22p/L17e 8 108 2.5E-32 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 SMD11_RS18910 0cd32ce466e68e128ff26680cca1a521 115 SUPERFAMILY SSF54843 1 112 7.19E-42 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 SMD11_RS18910 0cd32ce466e68e128ff26680cca1a521 115 Gene3D G3DSA:3.90.470.10 1 112 4.0E-42 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 SMD11_RS27300 0d096d67deffdd88ca6da12d6e0bf570 178 Hamap MF_00109 Shikimate kinase [aroK]. 3 167 26.245 T 06-07-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SMD11_RS27300 0d096d67deffdd88ca6da12d6e0bf570 178 Pfam PF01202 Shikimate kinase 12 166 3.9E-42 T 06-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SMD11_RS27300 0d096d67deffdd88ca6da12d6e0bf570 178 Gene3D G3DSA:3.40.50.300 4 166 2.2E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27300 0d096d67deffdd88ca6da12d6e0bf570 178 PRINTS PR01100 Shikimate kinase family signature 6 21 7.5E-15 T 06-07-2017 SMD11_RS27300 0d096d67deffdd88ca6da12d6e0bf570 178 PRINTS PR01100 Shikimate kinase family signature 96 113 7.5E-15 T 06-07-2017 SMD11_RS27300 0d096d67deffdd88ca6da12d6e0bf570 178 PRINTS PR01100 Shikimate kinase family signature 30 43 7.5E-15 T 06-07-2017 SMD11_RS27300 0d096d67deffdd88ca6da12d6e0bf570 178 PRINTS PR01100 Shikimate kinase family signature 58 66 7.5E-15 T 06-07-2017 SMD11_RS27300 0d096d67deffdd88ca6da12d6e0bf570 178 PRINTS PR01100 Shikimate kinase family signature 76 85 7.5E-15 T 06-07-2017 SMD11_RS27300 0d096d67deffdd88ca6da12d6e0bf570 178 SMART SM00382 2 145 0.0011 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS27300 0d096d67deffdd88ca6da12d6e0bf570 178 SUPERFAMILY SSF52540 3 166 2.25E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27300 0d096d67deffdd88ca6da12d6e0bf570 178 ProSitePatterns PS01128 Shikimate kinase signature. 59 84 - T 06-07-2017 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SMD11_RS33070 ed63170bd52cfd02e6e1a7ba09f3fd30 295 Gene3D G3DSA:3.40.190.10 174 258 5.4E-24 T 06-07-2017 SMD11_RS33070 ed63170bd52cfd02e6e1a7ba09f3fd30 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.3E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS33070 ed63170bd52cfd02e6e1a7ba09f3fd30 295 Gene3D G3DSA:1.10.10.10 1 86 1.4E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33070 ed63170bd52cfd02e6e1a7ba09f3fd30 295 Gene3D G3DSA:3.40.190.10 102 173 2.1E-15 T 06-07-2017 SMD11_RS33070 ed63170bd52cfd02e6e1a7ba09f3fd30 295 SUPERFAMILY SSF53850 101 290 5.34E-37 T 06-07-2017 SMD11_RS33070 ed63170bd52cfd02e6e1a7ba09f3fd30 295 SUPERFAMILY SSF46785 1 86 1.58E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33070 ed63170bd52cfd02e6e1a7ba09f3fd30 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS33070 ed63170bd52cfd02e6e1a7ba09f3fd30 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS33070 ed63170bd52cfd02e6e1a7ba09f3fd30 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS33070 ed63170bd52cfd02e6e1a7ba09f3fd30 295 Pfam PF03466 LysR substrate binding domain 94 289 3.6E-42 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS31790 315946cb4bc729f484f816a64c3cfa9e 351 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 65 79 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD11_RS31790 315946cb4bc729f484f816a64c3cfa9e 351 SUPERFAMILY SSF50129 9 176 3.04E-53 T 06-07-2017 IPR011032 GroES-like SMD11_RS31790 315946cb4bc729f484f816a64c3cfa9e 351 SUPERFAMILY SSF51735 154 316 1.78E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS31790 315946cb4bc729f484f816a64c3cfa9e 351 Pfam PF00107 Zinc-binding dehydrogenase 190 310 1.7E-17 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS31790 315946cb4bc729f484f816a64c3cfa9e 351 SMART SM00829 16 346 3.1E-6 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS31790 315946cb4bc729f484f816a64c3cfa9e 351 Gene3D G3DSA:3.40.50.720 185 296 9.5E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS31790 315946cb4bc729f484f816a64c3cfa9e 351 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 148 3.8E-26 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS31790 315946cb4bc729f484f816a64c3cfa9e 351 Gene3D G3DSA:3.90.180.10 4 184 1.5E-64 T 06-07-2017 IPR011032 GroES-like SMD11_RS12355 8c1595941ab925844cc9086b0d6f3258 581 Gene3D G3DSA:2.60.40.10 199 279 1.4E-21 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS12355 8c1595941ab925844cc9086b0d6f3258 581 SUPERFAMILY SSF51445 290 568 1.22E-53 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS12355 8c1595941ab925844cc9086b0d6f3258 581 SMART SM00060 200 270 5.0E-16 T 06-07-2017 IPR003961 Fibronectin type III GO:0005515 SMD11_RS12355 8c1595941ab925844cc9086b0d6f3258 581 Gene3D G3DSA:2.60.120.260 57 191 1.4E-9 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS12355 8c1595941ab925844cc9086b0d6f3258 581 SUPERFAMILY SSF49265 197 281 1.57E-19 T 06-07-2017 IPR003961 Fibronectin type III GO:0005515 SMD11_RS12355 8c1595941ab925844cc9086b0d6f3258 581 Pfam PF00041 Fibronectin type III domain 202 273 5.6E-11 T 06-07-2017 IPR003961 Fibronectin type III GO:0005515 SMD11_RS12355 8c1595941ab925844cc9086b0d6f3258 581 Pfam PF00704 Glycosyl hydrolases family 18 295 562 6.9E-29 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 SMD11_RS12355 8c1595941ab925844cc9086b0d6f3258 581 ProSitePatterns PS01095 Chitinases family 18 active site. 399 407 - T 06-07-2017 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 SMD11_RS12355 8c1595941ab925844cc9086b0d6f3258 581 PRINTS PR00014 Fibronectin type III repeat signature 257 271 9.8E-5 T 06-07-2017 SMD11_RS12355 8c1595941ab925844cc9086b0d6f3258 581 PRINTS PR00014 Fibronectin type III repeat signature 239 257 9.8E-5 T 06-07-2017 SMD11_RS12355 8c1595941ab925844cc9086b0d6f3258 581 PRINTS PR00014 Fibronectin type III repeat signature 214 223 9.8E-5 T 06-07-2017 SMD11_RS12355 8c1595941ab925844cc9086b0d6f3258 581 SUPERFAMILY SSF49785 58 190 3.68E-11 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS12355 8c1595941ab925844cc9086b0d6f3258 581 Gene3D G3DSA:3.20.20.80 292 570 3.0E-60 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS12355 8c1595941ab925844cc9086b0d6f3258 581 Pfam PF02018 Carbohydrate binding domain 58 173 5.0E-13 T 06-07-2017 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 SMD11_RS12355 8c1595941ab925844cc9086b0d6f3258 581 SMART SM00636 293 562 2.0E-7 T 06-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 SMD11_RS08830 871eef298396f283e0020a68953d40db 647 Pfam PF06276 Ferric iron reductase FhuF-like transporter 464 625 7.0E-33 T 06-07-2017 IPR022770 Ferric iron reductase FhuF domain SMD11_RS08830 871eef298396f283e0020a68953d40db 647 Pfam PF04183 IucA / IucC family 187 418 6.1E-63 T 06-07-2017 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 SMD11_RS28395 e3a04e7378e1b85a31f0efc2b36f5e7c 733 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 599 727 1.4E-63 T 06-07-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS28395 e3a04e7378e1b85a31f0efc2b36f5e7c 733 Pfam PF02310 B12 binding domain 602 712 1.4E-15 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD11_RS28395 e3a04e7378e1b85a31f0efc2b36f5e7c 733 SUPERFAMILY SSF52242 565 728 1.83E-60 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD11_RS28395 e3a04e7378e1b85a31f0efc2b36f5e7c 733 Gene3D G3DSA:3.40.50.280 566 726 1.3E-72 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD11_RS28395 e3a04e7378e1b85a31f0efc2b36f5e7c 733 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 384 409 - T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS28395 e3a04e7378e1b85a31f0efc2b36f5e7c 733 Pfam PF01642 Methylmalonyl-CoA mutase 42 560 1.8E-235 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS28395 e3a04e7378e1b85a31f0efc2b36f5e7c 733 Gene3D G3DSA:3.20.20.240 41 507 1.8E-210 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS28395 e3a04e7378e1b85a31f0efc2b36f5e7c 733 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 41 567 1.3E-280 T 06-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS28395 e3a04e7378e1b85a31f0efc2b36f5e7c 733 SUPERFAMILY SSF51703 25 562 1.57E-223 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS32155 cb41d47c58d7ad0a6b498b459084029f 255 SUPERFAMILY SSF48498 116 254 1.96E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS32155 cb41d47c58d7ad0a6b498b459084029f 255 Pfam PF00440 Bacterial regulatory proteins, tetR family 54 98 8.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS32155 cb41d47c58d7ad0a6b498b459084029f 255 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 110 254 1.4E-19 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD11_RS32155 cb41d47c58d7ad0a6b498b459084029f 255 Gene3D G3DSA:1.10.357.10 39 254 1.0E-53 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS32155 cb41d47c58d7ad0a6b498b459084029f 255 SUPERFAMILY SSF46689 42 106 1.4E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS16200 ef922a351b7321c0d442a453577958c1 145 SUPERFAMILY SSF54637 2 134 7.13E-22 T 06-07-2017 IPR029069 HotDog domain SMD11_RS16200 ef922a351b7321c0d442a453577958c1 145 Gene3D G3DSA:3.10.129.10 2 132 7.0E-22 T 06-07-2017 IPR029069 HotDog domain SMD11_RS16200 ef922a351b7321c0d442a453577958c1 145 Pfam PF01575 MaoC like domain 10 112 1.4E-6 T 06-07-2017 IPR002539 MaoC-like domain SMD11_RS19550 18977db1f8dc3f571af99323eed4b242 285 SUPERFAMILY SSF47413 10 71 1.08E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS19550 18977db1f8dc3f571af99323eed4b242 285 Gene3D G3DSA:1.10.260.40 6 73 3.5E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS19550 18977db1f8dc3f571af99323eed4b242 285 SMART SM00530 17 72 6.0E-14 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS19550 18977db1f8dc3f571af99323eed4b242 285 Pfam PF13560 Helix-turn-helix domain 13 70 4.5E-17 T 06-07-2017 SMD11_RS20080 2ee8819e1a8b2693a22b137019fa29ba 309 SUPERFAMILY SSF55060 167 290 1.53E-19 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain SMD11_RS20080 2ee8819e1a8b2693a22b137019fa29ba 309 SUPERFAMILY SSF54211 4 161 1.29E-41 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS20080 2ee8819e1a8b2693a22b137019fa29ba 309 PIRSF PIRSF010376 3 306 2.3E-75 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 SMD11_RS20080 2ee8819e1a8b2693a22b137019fa29ba 309 Pfam PF00288 GHMP kinases N terminal domain 89 147 2.8E-6 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 SMD11_RS20080 2ee8819e1a8b2693a22b137019fa29ba 309 Gene3D G3DSA:3.30.70.890 167 289 7.1E-24 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain SMD11_RS20080 2ee8819e1a8b2693a22b137019fa29ba 309 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 5 298 29.573 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 SMD11_RS20080 2ee8819e1a8b2693a22b137019fa29ba 309 Gene3D G3DSA:3.30.230.10 5 161 2.3E-48 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS20080 2ee8819e1a8b2693a22b137019fa29ba 309 Pfam PF08544 GHMP kinases C terminal 212 288 2.6E-9 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain SMD11_RS20080 2ee8819e1a8b2693a22b137019fa29ba 309 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 5 282 3.5E-49 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 Pfam PF13185 GAF domain 1123 1265 2.3E-16 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 Pfam PF00672 HAMP domain 309 360 1.3E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 Pfam PF00672 HAMP domain 585 636 1.2E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 Pfam PF00672 HAMP domain 861 911 1.8E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 Pfam PF00672 HAMP domain 678 728 2.2E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00304 864 916 2.0E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00304 772 824 9.2E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00304 404 456 6.9E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00304 680 732 1.3E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00304 312 364 1.8E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00304 588 640 3.5E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00304 26 78 1.3 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00304 118 180 0.0029 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00304 956 1008 2.9E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00304 1048 1100 1.0E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00304 496 548 1.2E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00304 220 272 2.0E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 Gene3D G3DSA:3.30.565.10 1427 1598 2.9E-43 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00387 1467 1600 2.4E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1467 1599 3.3E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00065 1124 1277 6.2E-6 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SUPERFAMILY SSF58104 332 465 6.54E-10 T 06-07-2017 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 Gene3D G3DSA:3.30.450.40 1107 1267 8.7E-20 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SUPERFAMILY SSF47384 1338 1422 5.1E-21 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SUPERFAMILY SSF55874 1409 1598 2.36E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SUPERFAMILY SSF52172 1716 1838 1.12E-35 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00448 1719 1833 8.1E-35 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SMART SM00388 1352 1420 1.1E-23 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1560 1578 1.7E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1543 1553 1.7E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1584 1597 1.7E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1525 1539 1.7E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 Gene3D G3DSA:3.40.50.2300 1717 1838 1.0E-38 T 06-07-2017 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SUPERFAMILY SSF55781 1087 1267 4.32E-25 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SUPERFAMILY SSF58104 157 328 1.36E-8 T 06-07-2017 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 Gene3D G3DSA:1.10.287.130 1343 1416 3.8E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SUPERFAMILY SSF58104 516 645 9.59E-12 T 06-07-2017 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SUPERFAMILY SSF58104 976 1098 3.92E-10 T 06-07-2017 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1353 1420 4.4E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 Pfam PF00072 Response regulator receiver domain 1721 1832 2.3E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS09025 bd3d4a36fc1f81f2a470d3c84b3d1653 1840 SUPERFAMILY SSF58104 700 970 2.88E-18 T 06-07-2017 SMD11_RS28585 6b1cccbd9b00203d784f98aabbdb8b09 275 Gene3D G3DSA:1.20.910.10 30 262 1.2E-5 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS28585 6b1cccbd9b00203d784f98aabbdb8b09 275 Pfam PF11251 Protein of unknown function (DUF3050) 30 257 6.2E-90 T 06-07-2017 IPR024423 Protein of unknown function DUF3050 SMD11_RS28585 6b1cccbd9b00203d784f98aabbdb8b09 275 SUPERFAMILY SSF48613 149 261 4.89E-7 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 PRINTS PR00359 B-class P450 signature 291 302 8.8E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 PRINTS PR00359 B-class P450 signature 215 237 8.8E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 PRINTS PR00359 B-class P450 signature 336 351 8.8E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 PRINTS PR00359 B-class P450 signature 357 366 8.8E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 PRINTS PR00359 B-class P450 signature 178 193 8.8E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 PRINTS PR00359 B-class P450 signature 308 335 8.8E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 PRINTS PR00359 B-class P450 signature 366 377 8.8E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 PRINTS PR00359 B-class P450 signature 114 125 8.8E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 PRINTS PR00359 B-class P450 signature 161 177 8.8E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 359 368 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 Pfam PF00067 Cytochrome P450 224 388 7.1E-25 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 SUPERFAMILY SSF48264 37 417 1.07E-89 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 PRINTS PR00385 P450 superfamily signature 357 366 2.5E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 PRINTS PR00385 P450 superfamily signature 366 377 2.5E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 PRINTS PR00385 P450 superfamily signature 291 302 2.5E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 PRINTS PR00385 P450 superfamily signature 256 273 2.5E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS04820 fec703614ca33ca9119f6d566925c8e4 419 Gene3D G3DSA:1.10.630.10 27 418 4.1E-116 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06220 b75eb2c7c17351da096685f42d74fb03 404 SUPERFAMILY SSF111321 86 379 1.57E-40 T 06-07-2017 IPR002791 Domain of unknown function DUF89 SMD11_RS06220 b75eb2c7c17351da096685f42d74fb03 404 Pfam PF01937 Protein of unknown function DUF89 35 381 1.1E-71 T 06-07-2017 IPR002791 Domain of unknown function DUF89 SMD11_RS27935 02ad1bc524f6d57d9f3b9436de3eed6f 433 Pfam PF01098 Cell cycle protein 55 422 1.7E-71 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 SMD11_RS32970 937b9f2874749202d71b0cf74eb8c916 287 SUPERFAMILY SSF53633 1 265 2.75E-47 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS32970 937b9f2874749202d71b0cf74eb8c916 287 TIGRFAM TIGR00761 argB: acetylglutamate kinase 4 248 1.3E-51 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS32970 937b9f2874749202d71b0cf74eb8c916 287 PIRSF PIRSF000728 1 271 1.0E-59 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS32970 937b9f2874749202d71b0cf74eb8c916 287 Gene3D G3DSA:3.40.1160.10 1 263 3.8E-57 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS32970 937b9f2874749202d71b0cf74eb8c916 287 Pfam PF00696 Amino acid kinase family 4 250 1.5E-34 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS16000 f2736030a1db6e9f8b96003922729fc8 382 PIRSF PIRSF036915 3 381 9.4E-97 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS16000 f2736030a1db6e9f8b96003922729fc8 382 Hamap MF_00493 Transaldolase [tal]. 1 380 89.168 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS16000 f2736030a1db6e9f8b96003922729fc8 382 SUPERFAMILY SSF51569 18 372 2.3E-40 T 06-07-2017 SMD11_RS16000 f2736030a1db6e9f8b96003922729fc8 382 Gene3D G3DSA:3.20.20.70 13 369 9.1E-68 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS16000 f2736030a1db6e9f8b96003922729fc8 382 TIGRFAM TIGR00876 tal_mycobact: transaldolase 20 366 6.0E-71 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS16000 f2736030a1db6e9f8b96003922729fc8 382 Pfam PF00923 Transaldolase 32 367 1.4E-31 T 06-07-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 SMD11_RS31730 f95e68f84104bf9f1f1b25c101a4954e 598 SUPERFAMILY SSF52540 355 574 3.0E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31730 f95e68f84104bf9f1f1b25c101a4954e 598 SMART SM00382 385 571 1.0E-20 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS31730 f95e68f84104bf9f1f1b25c101a4954e 598 Gene3D G3DSA:1.20.1560.10 13 341 3.0E-70 T 06-07-2017 SMD11_RS31730 f95e68f84104bf9f1f1b25c101a4954e 598 SUPERFAMILY SSF90123 14 345 1.57E-68 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS31730 f95e68f84104bf9f1f1b25c101a4954e 598 ProSitePatterns PS00211 ABC transporters family signature. 497 511 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS31730 f95e68f84104bf9f1f1b25c101a4954e 598 Pfam PF00664 ABC transporter transmembrane region 26 312 9.0E-43 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS31730 f95e68f84104bf9f1f1b25c101a4954e 598 Pfam PF00005 ABC transporter 376 525 1.7E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS31730 f95e68f84104bf9f1f1b25c101a4954e 598 Gene3D G3DSA:3.40.50.300 361 576 2.9E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07430 287b1b670160b0ceb95035939af511fc 484 Gene3D G3DSA:3.40.50.720 8 50 1.3E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS07430 287b1b670160b0ceb95035939af511fc 484 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 8 471 7.5E-63 T 06-07-2017 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SMD11_RS07430 287b1b670160b0ceb95035939af511fc 484 Gene3D G3DSA:3.90.660.20 242 421 1.6E-36 T 06-07-2017 IPR027418 Protoporphyrinogen oxidase, C-terminal domain KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SMD11_RS07430 287b1b670160b0ceb95035939af511fc 484 SUPERFAMILY SSF51905 10 327 1.89E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07430 287b1b670160b0ceb95035939af511fc 484 SUPERFAMILY SSF51905 438 470 1.89E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07430 287b1b670160b0ceb95035939af511fc 484 Gene3D G3DSA:1.10.3110.10 110 202 5.4E-22 T 06-07-2017 SMD11_RS07430 287b1b670160b0ceb95035939af511fc 484 Pfam PF01593 Flavin containing amine oxidoreductase 18 470 7.4E-47 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD11_RS07430 287b1b670160b0ceb95035939af511fc 484 SUPERFAMILY SSF54373 311 421 6.87E-27 T 06-07-2017 SMD11_RS08355 7915b6413f45bc5ddf6ec615d82401ca 143 SMART SM00960 10 104 5.1E-15 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS08355 7915b6413f45bc5ddf6ec615d82401ca 143 Gene3D G3DSA:3.30.450.30 6 131 1.5E-19 T 06-07-2017 SMD11_RS08355 7915b6413f45bc5ddf6ec615d82401ca 143 Pfam PF03259 Roadblock/LC7 domain 13 103 1.0E-17 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS08355 7915b6413f45bc5ddf6ec615d82401ca 143 SUPERFAMILY SSF103196 6 133 5.23E-24 T 06-07-2017 SMD11_RS32185 0b9256072a1c1023d9e6cb7a566b4c8b 186 Gene3D G3DSA:3.90.79.10 21 153 1.0E-17 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS32185 0b9256072a1c1023d9e6cb7a566b4c8b 186 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD11_RS32185 0b9256072a1c1023d9e6cb7a566b4c8b 186 Pfam PF00293 NUDIX domain 25 139 3.2E-15 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS32185 0b9256072a1c1023d9e6cb7a566b4c8b 186 SUPERFAMILY SSF55811 19 154 7.04E-18 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS21050 dca2a7d9b9fe95782e71e4aadbd3e419 299 SUPERFAMILY SSF56176 9 175 5.56E-41 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS21050 dca2a7d9b9fe95782e71e4aadbd3e419 299 SUPERFAMILY SSF55447 180 238 8.79E-6 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMD11_RS21050 dca2a7d9b9fe95782e71e4aadbd3e419 299 Gene3D G3DSA:3.30.43.10 15 55 1.5E-8 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS21050 dca2a7d9b9fe95782e71e4aadbd3e419 299 Gene3D G3DSA:3.30.465.10 62 175 3.7E-28 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS21050 dca2a7d9b9fe95782e71e4aadbd3e419 299 Gene3D G3DSA:3.30.390.50 181 271 5.8E-6 T 06-07-2017 SMD11_RS21050 dca2a7d9b9fe95782e71e4aadbd3e419 299 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 12 175 7.3E-41 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMD11_RS12750 21a0d8886a8ba14011412e299c4dbd48 336 Gene3D G3DSA:3.40.190.10 131 216 2.5E-22 T 06-07-2017 SMD11_RS12750 21a0d8886a8ba14011412e299c4dbd48 336 Pfam PF03466 LysR substrate binding domain 129 329 2.8E-48 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS12750 21a0d8886a8ba14011412e299c4dbd48 336 Gene3D G3DSA:1.10.10.10 47 125 2.9E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12750 21a0d8886a8ba14011412e299c4dbd48 336 SUPERFAMILY SSF53850 130 333 6.34E-43 T 06-07-2017 SMD11_RS12750 21a0d8886a8ba14011412e299c4dbd48 336 SUPERFAMILY SSF46785 46 125 6.49E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12750 21a0d8886a8ba14011412e299c4dbd48 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 59 70 1.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS12750 21a0d8886a8ba14011412e299c4dbd48 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 80 91 1.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS12750 21a0d8886a8ba14011412e299c4dbd48 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 70 80 1.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS12750 21a0d8886a8ba14011412e299c4dbd48 336 Gene3D G3DSA:3.40.190.10 217 304 3.7E-30 T 06-07-2017 SMD11_RS12750 21a0d8886a8ba14011412e299c4dbd48 336 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 46 103 5.3E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS23180 1aa625b0976fb5ff29d1db244aaa5c2f 227 Pfam PF08281 Sigma-70, region 4 118 168 1.1E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23180 1aa625b0976fb5ff29d1db244aaa5c2f 227 SUPERFAMILY SSF88946 3 94 5.89E-21 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23180 1aa625b0976fb5ff29d1db244aaa5c2f 227 Gene3D G3DSA:1.10.10.10 110 174 7.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23180 1aa625b0976fb5ff29d1db244aaa5c2f 227 Gene3D G3DSA:1.10.1740.10 3 101 3.3E-27 T 06-07-2017 SMD11_RS23180 1aa625b0976fb5ff29d1db244aaa5c2f 227 Pfam PF04542 Sigma-70 region 2 16 84 4.7E-15 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23180 1aa625b0976fb5ff29d1db244aaa5c2f 227 SUPERFAMILY SSF88659 110 171 1.24E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23180 1aa625b0976fb5ff29d1db244aaa5c2f 227 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 170 5.3E-25 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS22025 9a391408911125ce9c4f9b8a8901c181 554 Gene3D G3DSA:3.40.50.300 8 105 8.8E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22025 9a391408911125ce9c4f9b8a8901c181 554 Gene3D G3DSA:3.40.50.300 138 284 8.8E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22025 9a391408911125ce9c4f9b8a8901c181 554 SMART SM00382 30 233 2.3E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS22025 9a391408911125ce9c4f9b8a8901c181 554 SMART SM00382 346 516 1.3E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS22025 9a391408911125ce9c4f9b8a8901c181 554 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS22025 9a391408911125ce9c4f9b8a8901c181 554 SUPERFAMILY SSF52540 307 514 1.1E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22025 9a391408911125ce9c4f9b8a8901c181 554 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 551 7.2E-274 T 06-07-2017 IPR022374 ABC transporter, ATP-binding protein, ChvD SMD11_RS22025 9a391408911125ce9c4f9b8a8901c181 554 SUPERFAMILY SSF52540 13 241 2.02E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22025 9a391408911125ce9c4f9b8a8901c181 554 Pfam PF12848 ABC transporter 227 299 4.9E-11 T 06-07-2017 IPR032781 ABC-transporter extension domain SMD11_RS22025 9a391408911125ce9c4f9b8a8901c181 554 Gene3D G3DSA:3.40.50.300 320 529 1.4E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22025 9a391408911125ce9c4f9b8a8901c181 554 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS22025 9a391408911125ce9c4f9b8a8901c181 554 Pfam PF00005 ABC transporter 21 188 1.1E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS22025 9a391408911125ce9c4f9b8a8901c181 554 Pfam PF00005 ABC transporter 338 471 6.5E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS10865 fb06b4aa7250ae62d6100c35bdee7f41 695 SMART SM00959 50 90 3.2E-11 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 SMD11_RS10865 fb06b4aa7250ae62d6100c35bdee7f41 695 SUPERFAMILY SSF52540 361 639 3.07E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10865 fb06b4aa7250ae62d6100c35bdee7f41 695 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 428 632 2.7E-20 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD11_RS10865 fb06b4aa7250ae62d6100c35bdee7f41 695 SUPERFAMILY SSF50249 323 396 2.4E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS10865 fb06b4aa7250ae62d6100c35bdee7f41 695 Gene3D G3DSA:2.40.50.140 51 90 7.6E-41 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS10865 fb06b4aa7250ae62d6100c35bdee7f41 695 Gene3D G3DSA:2.40.50.140 318 397 7.6E-41 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS10865 fb06b4aa7250ae62d6100c35bdee7f41 695 SMART SM00382 439 624 2.9E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS10865 fb06b4aa7250ae62d6100c35bdee7f41 695 Gene3D G3DSA:3.40.50.300 403 686 1.9E-98 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10865 fb06b4aa7250ae62d6100c35bdee7f41 695 SMART SM00357 324 390 1.1E-11 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 SMD11_RS10865 fb06b4aa7250ae62d6100c35bdee7f41 695 TIGRFAM TIGR00767 rho: transcription termination factor Rho 51 686 3.8E-200 T 06-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 SMD11_RS10865 fb06b4aa7250ae62d6100c35bdee7f41 695 Pfam PF07498 Rho termination factor, N-terminal domain 51 88 1.4E-10 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 SMD11_RS10865 fb06b4aa7250ae62d6100c35bdee7f41 695 SUPERFAMILY SSF68912 50 88 3.92E-5 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 SMD11_RS10865 fb06b4aa7250ae62d6100c35bdee7f41 695 Hamap MF_01884 Transcription termination factor Rho [rho]. 315 688 204.011 T 06-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 SMD11_RS10865 fb06b4aa7250ae62d6100c35bdee7f41 695 Pfam PF07497 Rho termination factor, RNA-binding domain 323 397 5.7E-28 T 06-07-2017 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 SMD11_RS24675 c7dd91081476227ce02a75393d1a020f 443 Pfam PF00815 Histidinol dehydrogenase 25 435 1.9E-156 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD11_RS24675 c7dd91081476227ce02a75393d1a020f 443 SUPERFAMILY SSF53720 30 437 1.86E-70 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS24675 c7dd91081476227ce02a75393d1a020f 443 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 38 434 8.0E-141 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD11_RS24675 c7dd91081476227ce02a75393d1a020f 443 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 12 435 38.402 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD11_RS24675 c7dd91081476227ce02a75393d1a020f 443 PIRSF PIRSF000099 8 438 1.8E-158 T 06-07-2017 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD11_RS24675 c7dd91081476227ce02a75393d1a020f 443 Gene3D G3DSA:3.40.50.1980 32 245 3.4E-78 T 06-07-2017 SMD11_RS24675 c7dd91081476227ce02a75393d1a020f 443 PRINTS PR00083 Histidinol dehydrogenase signature 257 276 4.3E-81 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD11_RS24675 c7dd91081476227ce02a75393d1a020f 443 PRINTS PR00083 Histidinol dehydrogenase signature 38 62 4.3E-81 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD11_RS24675 c7dd91081476227ce02a75393d1a020f 443 PRINTS PR00083 Histidinol dehydrogenase signature 139 165 4.3E-81 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD11_RS24675 c7dd91081476227ce02a75393d1a020f 443 PRINTS PR00083 Histidinol dehydrogenase signature 235 256 4.3E-81 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD11_RS24675 c7dd91081476227ce02a75393d1a020f 443 PRINTS PR00083 Histidinol dehydrogenase signature 328 353 4.3E-81 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD11_RS24675 c7dd91081476227ce02a75393d1a020f 443 PRINTS PR00083 Histidinol dehydrogenase signature 369 387 4.3E-81 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD11_RS24675 c7dd91081476227ce02a75393d1a020f 443 PRINTS PR00083 Histidinol dehydrogenase signature 176 202 4.3E-81 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD11_RS24675 c7dd91081476227ce02a75393d1a020f 443 PRINTS PR00083 Histidinol dehydrogenase signature 206 231 4.3E-81 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 SMD11_RS24675 c7dd91081476227ce02a75393d1a020f 443 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 235 267 - T 06-07-2017 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 SMD11_RS03725 dde3b1a1e094be0368c772db16f15048 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 93 2.0E-4 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS03725 dde3b1a1e094be0368c772db16f15048 331 Pfam PF00107 Zinc-binding dehydrogenase 153 271 1.1E-31 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS03725 dde3b1a1e094be0368c772db16f15048 331 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 142 163 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMD11_RS03725 dde3b1a1e094be0368c772db16f15048 331 Gene3D G3DSA:3.90.180.10 1 147 2.3E-40 T 06-07-2017 IPR011032 GroES-like SMD11_RS03725 dde3b1a1e094be0368c772db16f15048 331 SUPERFAMILY SSF51735 114 273 7.8E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03725 dde3b1a1e094be0368c772db16f15048 331 SMART SM00829 13 324 5.8E-40 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS03725 dde3b1a1e094be0368c772db16f15048 331 SUPERFAMILY SSF50129 1 142 1.67E-33 T 06-07-2017 IPR011032 GroES-like SMD11_RS03725 dde3b1a1e094be0368c772db16f15048 331 Gene3D G3DSA:3.40.50.720 148 263 1.2E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17585 15e075cb070d10b01bec773c24f55640 168 Gene3D G3DSA:1.10.10.10 17 150 1.9E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17585 15e075cb070d10b01bec773c24f55640 168 SUPERFAMILY SSF46785 17 149 2.1E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17585 15e075cb070d10b01bec773c24f55640 168 Pfam PF13463 Winged helix DNA-binding domain 43 108 1.4E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS29385 cae3ea79082977015f37209e3e755d8a 579 Pfam PF00501 AMP-binding enzyme 59 443 3.5E-43 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS29385 cae3ea79082977015f37209e3e755d8a 579 Gene3D G3DSA:3.40.50.980 55 195 3.8E-18 T 06-07-2017 SMD11_RS29385 cae3ea79082977015f37209e3e755d8a 579 SUPERFAMILY SSF56801 59 554 2.35E-71 T 06-07-2017 SMD11_RS29385 cae3ea79082977015f37209e3e755d8a 579 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS29385 cae3ea79082977015f37209e3e755d8a 579 Gene3D G3DSA:3.30.300.30 456 554 7.6E-6 T 06-07-2017 SMD11_RS29385 cae3ea79082977015f37209e3e755d8a 579 Gene3D G3DSA:2.30.38.10 365 438 1.3E-13 T 06-07-2017 SMD11_RS29385 cae3ea79082977015f37209e3e755d8a 579 Gene3D G3DSA:3.40.50.980 196 316 1.0E-11 T 06-07-2017 SMD11_RS03150 307078dd9308c2c9097866d8a8241a1e 264 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 10 148 1.7E-18 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD11_RS03150 307078dd9308c2c9097866d8a8241a1e 264 Pfam PF07398 MDMPI C-terminal domain 161 256 1.1E-10 T 06-07-2017 IPR010872 MDMPI C-terminal SMD11_RS03150 307078dd9308c2c9097866d8a8241a1e 264 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 9 239 1.0E-22 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD11_RS03150 307078dd9308c2c9097866d8a8241a1e 264 SUPERFAMILY SSF109854 4 154 5.8E-8 T 06-07-2017 SMD11_RS23475 30c2ca830e5ddecabac31cbb181cf4e2 380 Pfam PF02361 Cobalt transport protein 85 242 5.0E-6 T 06-07-2017 IPR003339 ABC/ECF transporter, transmembrane component SMD11_RS26455 5b74bb41449ed4834dfcda3117b0ae42 236 Pfam PF13419 Haloacid dehalogenase-like hydrolase 21 199 6.0E-26 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS26455 5b74bb41449ed4834dfcda3117b0ae42 236 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 74 199 1.6E-15 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD11_RS26455 5b74bb41449ed4834dfcda3117b0ae42 236 SUPERFAMILY SSF56784 19 219 1.82E-45 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS26455 5b74bb41449ed4834dfcda3117b0ae42 236 Gene3D G3DSA:3.40.50.1000 16 32 3.5E-41 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS26455 5b74bb41449ed4834dfcda3117b0ae42 236 Gene3D G3DSA:3.40.50.1000 104 220 3.5E-41 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS26455 5b74bb41449ed4834dfcda3117b0ae42 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 1.7E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD11_RS26455 5b74bb41449ed4834dfcda3117b0ae42 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 18 29 1.7E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD11_RS26455 5b74bb41449ed4834dfcda3117b0ae42 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 181 1.7E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD11_RS26455 5b74bb41449ed4834dfcda3117b0ae42 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 1.7E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD11_RS15965 7109cdf303b00f7fbf5d6dd7164a42dc 525 SUPERFAMILY SSF56801 18 518 3.79E-62 T 06-07-2017 SMD11_RS15965 7109cdf303b00f7fbf5d6dd7164a42dc 525 Gene3D G3DSA:3.40.50.980 18 183 5.6E-19 T 06-07-2017 SMD11_RS15965 7109cdf303b00f7fbf5d6dd7164a42dc 525 Gene3D G3DSA:2.30.38.10 352 424 8.4E-8 T 06-07-2017 SMD11_RS15965 7109cdf303b00f7fbf5d6dd7164a42dc 525 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS15965 7109cdf303b00f7fbf5d6dd7164a42dc 525 Pfam PF00501 AMP-binding enzyme 18 429 1.5E-39 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS15965 7109cdf303b00f7fbf5d6dd7164a42dc 525 Gene3D G3DSA:3.40.50.980 184 332 1.8E-14 T 06-07-2017 SMD11_RS11415 088595626a1b928fdf4892144ab2d794 453 Gene3D G3DSA:3.65.10.10 256 439 4.7E-53 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD11_RS11415 088595626a1b928fdf4892144ab2d794 453 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 18 435 1.8E-107 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD11_RS11415 088595626a1b928fdf4892144ab2d794 453 Gene3D G3DSA:3.65.10.10 30 255 1.4E-63 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD11_RS11415 088595626a1b928fdf4892144ab2d794 453 PIRSF PIRSF000505 10 446 1.7E-114 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD11_RS11415 088595626a1b928fdf4892144ab2d794 453 ProSitePatterns PS00885 EPSP synthase signature 2. 356 374 - T 06-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD11_RS11415 088595626a1b928fdf4892144ab2d794 453 ProSitePatterns PS00104 EPSP synthase signature 1. 103 117 - T 06-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD11_RS11415 088595626a1b928fdf4892144ab2d794 453 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 18 443 28.818 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD11_RS11415 088595626a1b928fdf4892144ab2d794 453 SUPERFAMILY SSF55205 19 439 3.53E-100 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SMD11_RS11415 088595626a1b928fdf4892144ab2d794 453 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 23 440 4.1E-114 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD11_RS10920 f7410018e3bf2ef1fc6706ca58903058 381 SUPERFAMILY SSF47240 89 318 5.03E-66 T 06-07-2017 IPR009078 Ferritin-like superfamily SMD11_RS10920 f7410018e3bf2ef1fc6706ca58903058 381 Gene3D G3DSA:1.10.620.20 34 253 1.7E-15 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 SMD11_RS10920 f7410018e3bf2ef1fc6706ca58903058 381 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 34 304 2.9E-16 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF SMD11_RS21030 148f7a7b38e34bb49a0ee7fb94193957 453 Pfam PF13416 Bacterial extracellular solute-binding protein 83 385 6.0E-34 T 06-07-2017 SMD11_RS21030 148f7a7b38e34bb49a0ee7fb94193957 453 Gene3D G3DSA:3.40.190.10 194 382 9.1E-41 T 06-07-2017 SMD11_RS21030 148f7a7b38e34bb49a0ee7fb94193957 453 Gene3D G3DSA:3.40.190.10 75 193 3.2E-19 T 06-07-2017 SMD11_RS21030 148f7a7b38e34bb49a0ee7fb94193957 453 SUPERFAMILY SSF53850 62 448 6.21E-72 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF52151 7229 7349 1.23E-77 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF52151 7408 7513 1.23E-77 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.47.10 6701 6963 1.8E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 ProSitePatterns PS00012 Phosphopantetheine attachment site. 8352 8367 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF55048 5644 5705 1.96E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF52151 5698 5807 2.56E-77 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF52151 5518 5639 2.56E-77 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 6864 6880 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5151 5167 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF51735 4448 4608 2.4E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 7079 7192 2.8E-16 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3666 3779 1.7E-14 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1939 2059 2.4E-17 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 529 8.7E-16 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5366 5483 2.2E-16 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1561 1811 3.3E-96 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6703 6951 1.3E-92 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 283 1.8E-88 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3290 3538 4.8E-92 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4992 5238 2.3E-89 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00823 Phosphopantetheine attachment site 1470 1542 1.2E-31 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00823 Phosphopantetheine attachment site 6611 6683 2.6E-31 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00823 Phosphopantetheine attachment site 4900 4972 5.9E-32 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00823 Phosphopantetheine attachment site 8325 8397 2.7E-31 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00823 Phosphopantetheine attachment site 3196 3268 1.6E-31 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3818 4109 8.7E-129 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5521 5812 9.1E-127 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 565 865 3.3E-125 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2098 2389 2.1E-129 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7231 7522 6.4E-130 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.50.720 6332 6541 1.9E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.50.720 1188 1369 4.3E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.50.720 2919 3128 3.5E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.50.720 4621 4830 6.7E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.50.720 8046 8255 6.3E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF51735 7861 8033 4.92E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4927 4942 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF08659 KR domain 4622 4796 1.1E-60 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF08659 KR domain 1188 1366 5.4E-63 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF08659 KR domain 8047 8221 1.1E-59 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF08659 KR domain 6333 6507 7.2E-61 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF08659 KR domain 2919 3092 1.3E-61 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF52151 562 693 1.49E-71 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF52151 757 853 1.49E-71 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF51735 2740 2906 1.93E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3546 3663 1.1E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 6959 7076 8.7E-44 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1819 1936 1.3E-42 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5246 5363 1.1E-42 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 408 5.9E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF55048 2221 2282 3.27E-12 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF00550 Phosphopantetheine attachment site 3198 3264 2.1E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF00550 Phosphopantetheine attachment site 8327 8393 1.1E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF00550 Phosphopantetheine attachment site 4902 4968 1.0E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF00550 Phosphopantetheine attachment site 6613 6678 3.6E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF00550 Phosphopantetheine attachment site 1472 1538 8.0E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF47336 4894 5007 1.03E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.30.70.250 7354 7414 2.3E-8 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.30.70.250 3941 4001 4.5E-9 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.30.70.250 2220 2281 4.5E-10 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.30.70.250 692 755 4.2E-8 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.30.70.250 5643 5704 8.0E-10 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3223 3238 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF55048 3941 4002 5.89E-12 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF00698 Acyl transferase domain 564 867 5.3E-55 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF00698 Acyl transferase domain 5520 5830 4.1E-57 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF00698 Acyl transferase domain 2098 2407 2.4E-57 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF00698 Acyl transferase domain 7230 7534 8.6E-58 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF00698 Acyl transferase domain 3817 4128 2.4E-57 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.366.10 3812 3936 2.8E-82 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.366.10 7226 7349 4.8E-82 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.366.10 4002 4111 2.8E-82 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.366.10 2282 2391 2.7E-80 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.366.10 5705 5812 1.8E-81 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.366.10 756 869 5.1E-78 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.366.10 5513 5639 1.8E-81 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.366.10 2090 2216 2.7E-80 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.366.10 7415 7524 4.8E-82 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.366.10 558 687 5.1E-78 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF14765 Polyketide synthase dehydratase 4177 4444 2.4E-55 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF14765 Polyketide synthase dehydratase 5880 6147 7.2E-56 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF14765 Polyketide synthase dehydratase 7590 7857 2.1E-53 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF14765 Polyketide synthase dehydratase 2457 2731 1.6E-61 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF51735 8044 8259 4.9E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF55048 692 756 5.36E-13 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF53901 3287 3661 2.16E-104 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6638 6653 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF51735 6151 6319 7.87E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00826 2457 2623 3.6E-85 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00826 4177 4337 1.9E-84 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00826 5880 6040 5.9E-87 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00826 7590 7750 6.4E-86 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.47.10 1824 1987 1.8E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.47.10 3551 3715 2.4E-64 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.47.10 5251 5416 9.7E-64 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.47.10 6964 7128 5.0E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.47.10 296 462 2.0E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF47336 1464 1576 7.72E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1497 1512 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00825 Beta-ketoacyl synthase 1563 1989 1.0E-230 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00825 Beta-ketoacyl synthase 3292 3715 2.7E-225 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00825 Beta-ketoacyl synthase 6705 7129 1.8E-227 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00825 Beta-ketoacyl synthase 4994 5416 5.0E-220 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00825 Beta-ketoacyl synthase 36 461 2.4E-226 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM01294 8326 8393 1.1E-6 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM01294 6612 6679 3.3E-7 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM01294 4901 4968 9.8E-8 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM01294 1471 1538 1.3E-6 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM01294 3197 3264 3.1E-7 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1188 1367 4.4E-59 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8047 8223 3.6E-59 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2919 3094 5.5E-61 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6333 6509 5.6E-62 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4622 4798 5.2E-60 T 06-07-2017 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF51735 1184 1437 1.52E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3451 3467 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF51735 2917 3149 7.11E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1724 1740 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF47336 6606 6718 1.96E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:1.10.1200.10 1467 1543 6.4E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:1.10.1200.10 6607 6683 6.7E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:1.10.1200.10 3192 3268 7.5E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:1.10.1200.10 8321 8398 2.4E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:1.10.1200.10 4898 4972 1.1E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF53901 6700 7074 5.77E-105 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF51735 978 1174 4.72E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF55048 7354 7415 2.09E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF47336 8318 8403 1.57E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF47336 3190 3305 4.45E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF53901 30 406 4.22E-106 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF53901 4990 5361 2.07E-103 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF51735 4619 4856 1.56E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Pfam PF08990 Erythronolide synthase docking 2 27 3.8E-12 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF51735 6330 6565 8.39E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF53901 1559 1934 1.01E-105 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF52151 3995 4100 9.16E-78 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF52151 3816 3936 9.16E-78 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF52151 2275 2389 4.97E-76 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 SUPERFAMILY SSF52151 2096 2216 4.97E-76 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.47.10 3292 3550 1.8E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.47.10 36 295 3.7E-90 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.47.10 4994 5250 1.6E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32335 43e504f504ad0169f74769b63833c8c5 8485 Gene3D G3DSA:3.40.47.10 1563 1823 1.1E-97 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS16695 18208ad0546662e01cc26648c49789f9 375 Gene3D G3DSA:3.90.1150.10 241 353 2.6E-17 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS16695 18208ad0546662e01cc26648c49789f9 375 PIRSF PIRSF000524 17 374 2.9E-71 T 06-07-2017 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 SMD11_RS16695 18208ad0546662e01cc26648c49789f9 375 Gene3D G3DSA:3.40.640.10 17 240 2.2E-44 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS16695 18208ad0546662e01cc26648c49789f9 375 SUPERFAMILY SSF53383 19 352 4.03E-66 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS16695 18208ad0546662e01cc26648c49789f9 375 Pfam PF00266 Aminotransferase class-V 23 319 9.4E-28 T 06-07-2017 IPR000192 Aminotransferase class V domain SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 Pfam PF00069 Protein kinase domain 16 265 1.4E-35 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 Gene3D G3DSA:3.30.200.20 9 94 1.5E-14 T 06-07-2017 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 Gene3D G3DSA:2.130.10.10 361 473 2.2E-26 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 SUPERFAMILY SSF56112 13 297 9.31E-63 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 Gene3D G3DSA:1.10.510.10 96 285 3.5E-36 T 06-07-2017 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 Gene3D G3DSA:2.130.10.10 474 681 2.7E-34 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 SMART SM00320 628 681 380.0 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 SMART SM00320 443 481 8.5 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 SMART SM00320 529 567 3.1 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 SMART SM00320 484 526 1.1E-4 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 SMART SM00320 399 437 0.33 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 SMART SM00320 357 396 4.0E-9 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 Pfam PF00400 WD domain, G-beta repeat 489 526 0.043 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 Pfam PF00400 WD domain, G-beta repeat 360 396 1.1E-8 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 44 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 SUPERFAMILY SSF50998 356 666 1.41E-52 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 SMART SM00220 16 269 8.3E-42 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS19525 26819d6c33028f3d8362bbc65269ea38 683 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 383 397 - T 06-07-2017 IPR019775 WD40 repeat, conserved site SMD11_RS26970 0a97849b5bd34edf8243fe19781bc90f 264 Gene3D G3DSA:1.10.3720.10 8 215 1.0E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS26970 0a97849b5bd34edf8243fe19781bc90f 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 215 9.8E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS26970 0a97849b5bd34edf8243fe19781bc90f 264 SUPERFAMILY SSF161098 8 202 4.84E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS17770 0d3dc3ff334484deb9dfc2a7525a52f6 429 SUPERFAMILY SSF55874 302 420 7.97E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS17770 0d3dc3ff334484deb9dfc2a7525a52f6 429 Pfam PF07730 Histidine kinase 219 283 9.8E-19 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS01015 ad54d48a4cdde2161346e2df2d660595 187 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 2 54 2.5E-10 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMD11_RS01015 ad54d48a4cdde2161346e2df2d660595 187 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 61 166 2.0E-9 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMD11_RS01015 ad54d48a4cdde2161346e2df2d660595 187 SUPERFAMILY SSF50621 31 170 3.98E-26 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS01015 ad54d48a4cdde2161346e2df2d660595 187 Gene3D G3DSA:2.40.37.10 2 168 9.5E-33 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF00698 Acyl transferase domain 544 841 2.1E-51 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF00698 Acyl transferase domain 3925 4224 8.6E-53 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF00698 Acyl transferase domain 2226 2527 6.7E-56 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM00823 Phosphopantetheine attachment site 1618 1690 2.7E-31 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM00823 Phosphopantetheine attachment site 4725 4797 6.8E-31 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM00823 Phosphopantetheine attachment site 3323 3395 3.4E-31 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF51735 3036 3252 2.67E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3350 3365 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.40.47.10 296 463 1.2E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.40.47.10 3679 3844 4.9E-64 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.40.47.10 1977 2141 3.3E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.40.50.720 4474 4647 2.4E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.40.50.720 1339 1519 3.2E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM00825 Beta-ketoacyl synthase 1715 2143 2.4E-223 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM00825 Beta-ketoacyl synthase 37 462 6.7E-228 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM00825 Beta-ketoacyl synthase 3418 3844 3.5E-230 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.40.50.720 3038 3249 1.6E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM00826 2575 2723 1.9E-56 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM00826 891 1053 4.1E-84 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF08659 KR domain 4532 4628 2.2E-16 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF08659 KR domain 1340 1514 2.1E-52 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF08659 KR domain 3039 3217 8.7E-57 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF00550 Phosphopantetheine attachment site 1621 1686 1.7E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF00550 Phosphopantetheine attachment site 4731 4793 2.9E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF00550 Phosphopantetheine attachment site 3326 3391 4.6E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF55048 4041 4097 1.57E-9 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF51735 1336 1569 8.44E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF53901 3412 3788 6.87E-104 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 523 2.4E-14 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3794 3908 2.1E-16 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2092 2208 1.0E-9 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF51735 4271 4463 5.51E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF52151 2392 2495 1.75E-74 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF52151 2223 2337 1.75E-74 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF55048 660 716 3.66E-9 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF55048 2342 2398 3.27E-9 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF52151 710 814 1.15E-71 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF52151 541 655 1.15E-71 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.30.70.250 4040 4091 5.0E-7 T 06-07-2017 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.30.70.250 659 710 2.9E-6 T 06-07-2017 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.30.70.250 2341 2392 1.5E-6 T 06-07-2017 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF47336 4717 4800 4.84E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3674 3791 8.4E-42 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 408 2.7E-41 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1973 2089 8.0E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.40.366.10 716 825 5.3E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.40.366.10 2221 2337 1.1E-78 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.40.366.10 3920 4036 1.1E-77 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.40.366.10 4097 4207 1.1E-77 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.40.366.10 536 655 5.3E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.40.366.10 2398 2511 1.1E-78 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1645 1660 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF51735 4472 4649 1.11E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF51735 2840 3026 4.92E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4752 4767 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF53901 31 405 1.36E-102 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF53901 1711 2086 5.48E-101 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.40.47.10 33 295 1.2E-91 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.40.47.10 1711 1976 1.9E-93 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:3.40.47.10 3412 3678 1.2E-93 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF14765 Polyketide synthase dehydratase 2585 2834 1.2E-32 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF14765 Polyketide synthase dehydratase 891 1171 3.7E-51 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1713 1964 7.3E-93 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3416 3666 2.2E-95 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 283 5.3E-94 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 544 824 2.2E-112 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2226 2508 3.1E-121 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3925 4205 6.0E-120 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3579 3595 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1877 1893 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF51735 1177 1326 1.97E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF47336 1613 1728 4.84E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF52151 3922 4036 4.19E-74 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF52151 4091 4193 4.19E-74 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SUPERFAMILY SSF47336 3317 3431 1.57E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM01294 1619 1686 1.2E-6 T 06-07-2017 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM01294 3324 3391 1.9E-4 T 06-07-2017 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM01294 4726 4793 3.6E-6 T 06-07-2017 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3039 3219 9.8E-59 T 06-07-2017 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1340 1516 8.8E-53 T 06-07-2017 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4475 4630 2.2E-9 T 06-07-2017 SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:1.10.1200.10 1617 1690 1.1E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:1.10.1200.10 4722 4797 9.0E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08265 0ddbe733e4b1b1bdb9929518a8bbf45b 4906 Gene3D G3DSA:1.10.1200.10 3320 3397 1.3E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS02140 592a4cfb68b6b9c95c39ea94fdc5ab7e 334 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 196 207 1.9E-5 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS02140 592a4cfb68b6b9c95c39ea94fdc5ab7e 334 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 180 196 1.9E-5 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS02140 592a4cfb68b6b9c95c39ea94fdc5ab7e 334 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 207 226 1.9E-5 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS02140 592a4cfb68b6b9c95c39ea94fdc5ab7e 334 SMART SM00344 180 285 5.4E-11 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD11_RS02140 592a4cfb68b6b9c95c39ea94fdc5ab7e 334 SUPERFAMILY SSF46785 179 228 1.18E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02140 592a4cfb68b6b9c95c39ea94fdc5ab7e 334 Gene3D G3DSA:3.30.70.920 75 145 0.001 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS02140 592a4cfb68b6b9c95c39ea94fdc5ab7e 334 Gene3D G3DSA:3.30.70.920 243 318 9.9E-12 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS02140 592a4cfb68b6b9c95c39ea94fdc5ab7e 334 Pfam PF01037 Lrp/AsnC ligand binding domain 247 315 1.5E-7 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS02140 592a4cfb68b6b9c95c39ea94fdc5ab7e 334 Pfam PF13404 AsnC-type helix-turn-helix domain 180 221 1.5E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS02140 592a4cfb68b6b9c95c39ea94fdc5ab7e 334 Pfam PF13404 AsnC-type helix-turn-helix domain 11 51 2.8E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS02140 592a4cfb68b6b9c95c39ea94fdc5ab7e 334 Gene3D G3DSA:1.10.10.10 7 57 5.6E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02140 592a4cfb68b6b9c95c39ea94fdc5ab7e 334 Gene3D G3DSA:1.10.10.10 178 226 1.5E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02140 592a4cfb68b6b9c95c39ea94fdc5ab7e 334 SUPERFAMILY SSF46785 3 66 3.83E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02140 592a4cfb68b6b9c95c39ea94fdc5ab7e 334 SUPERFAMILY SSF54909 239 318 1.18E-9 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS18465 b76976bac55fbf11f4ca342d869ca73f 392 PIRSF PIRSF029171 1 390 1.1E-66 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 SMD11_RS18465 b76976bac55fbf11f4ca342d869ca73f 392 Pfam PF03583 Secretory lipase 122 387 5.1E-54 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 SMD11_RS18465 b76976bac55fbf11f4ca342d869ca73f 392 Gene3D G3DSA:3.40.50.1820 81 265 8.0E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS18465 b76976bac55fbf11f4ca342d869ca73f 392 Gene3D G3DSA:3.40.50.1820 299 365 8.0E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS18465 b76976bac55fbf11f4ca342d869ca73f 392 SUPERFAMILY SSF53474 80 226 2.91E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS18465 b76976bac55fbf11f4ca342d869ca73f 392 SUPERFAMILY SSF53474 290 373 2.91E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12235 7a8139b6d007bf8c1d9ea4008dec401a 177 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 177 84.932 T 06-07-2017 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS12235 7a8139b6d007bf8c1d9ea4008dec401a 177 SUPERFAMILY SSF69118 3 174 6.94E-50 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS12235 7a8139b6d007bf8c1d9ea4008dec401a 177 Pfam PF02627 Carboxymuconolactone decarboxylase family 94 175 4.9E-16 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS12235 7a8139b6d007bf8c1d9ea4008dec401a 177 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 3 176 2.3E-92 T 06-07-2017 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS12235 7a8139b6d007bf8c1d9ea4008dec401a 177 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 112 160 7.9E-21 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS12235 7a8139b6d007bf8c1d9ea4008dec401a 177 Gene3D G3DSA:1.20.1290.10 1 172 2.2E-58 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS16605 e95d496ccadbc61eebfbfc1cc22bb19f 403 Gene3D G3DSA:1.10.260.40 6 70 4.3E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS16605 e95d496ccadbc61eebfbfc1cc22bb19f 403 Pfam PF13428 Tetratricopeptide repeat 337 376 2.7E-5 T 06-07-2017 SMD11_RS16605 e95d496ccadbc61eebfbfc1cc22bb19f 403 Gene3D G3DSA:1.25.40.10 164 220 7.1E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS16605 e95d496ccadbc61eebfbfc1cc22bb19f 403 Gene3D G3DSA:1.25.40.10 254 385 7.1E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS16605 e95d496ccadbc61eebfbfc1cc22bb19f 403 SMART SM00530 13 69 6.8E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS16605 e95d496ccadbc61eebfbfc1cc22bb19f 403 SUPERFAMILY SSF47413 5 71 1.39E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS16605 e95d496ccadbc61eebfbfc1cc22bb19f 403 Pfam PF13560 Helix-turn-helix domain 9 68 1.8E-12 T 06-07-2017 SMD11_RS16745 f73d4c0c6915098a339f403147053152 502 Pfam PF03796 DnaB-like helicase C terminal domain 242 497 2.5E-108 T 06-07-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 SMD11_RS16745 f73d4c0c6915098a339f403147053152 502 SUPERFAMILY SSF52540 240 491 1.86E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16745 f73d4c0c6915098a339f403147053152 502 SMART SM00382 259 458 0.0014 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS16745 f73d4c0c6915098a339f403147053152 502 Gene3D G3DSA:1.10.860.10 67 169 1.6E-41 T 06-07-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal SMD11_RS16745 f73d4c0c6915098a339f403147053152 502 Gene3D G3DSA:3.40.50.300 227 500 2.1E-118 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16745 f73d4c0c6915098a339f403147053152 502 SUPERFAMILY SSF48024 65 176 2.09E-38 T 06-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SMD11_RS16745 f73d4c0c6915098a339f403147053152 502 Pfam PF00772 DnaB-like helicase N terminal domain 67 168 4.0E-36 T 06-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SMD11_RS16745 f73d4c0c6915098a339f403147053152 502 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 67 500 1.1E-165 T 06-07-2017 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 SMD11_RS19625 3b3cb0e48986b9b9b342889656c1a6c3 698 Pfam PF04471 Restriction endonuclease 372 484 1.1E-28 T 06-07-2017 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 SMD11_RS19625 3b3cb0e48986b9b9b342889656c1a6c3 698 Gene3D G3DSA:2.60.60.30 550 691 2.8E-21 T 06-07-2017 SMD11_RS19625 3b3cb0e48986b9b9b342889656c1a6c3 698 SUPERFAMILY SSF52980 376 484 2.68E-19 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD11_RS19625 3b3cb0e48986b9b9b342889656c1a6c3 698 Pfam PF02342 TerD domain 549 693 6.6E-21 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS19625 3b3cb0e48986b9b9b342889656c1a6c3 698 Gene3D G3DSA:3.40.1350.10 369 483 1.3E-21 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 SMD11_RS14370 4b4bad2de10e8e29f9db779cb25dd647 266 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 219 2.0E-28 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS14370 4b4bad2de10e8e29f9db779cb25dd647 266 SMART SM00862 145 219 3.6E-30 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS14370 4b4bad2de10e8e29f9db779cb25dd647 266 SUPERFAMILY SSF46894 125 221 2.65E-30 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS14370 4b4bad2de10e8e29f9db779cb25dd647 266 Gene3D G3DSA:1.10.10.10 123 221 1.8E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20735 bdbe508bd9bc81ba595f017d2cc67c30 322 SUPERFAMILY SSF161111 6 219 4.71E-38 T 06-07-2017 SMD11_RS20735 bdbe508bd9bc81ba595f017d2cc67c30 322 Gene3D G3DSA:3.30.70.1350 220 298 4.8E-6 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain SMD11_RS20735 bdbe508bd9bc81ba595f017d2cc67c30 322 SUPERFAMILY SSF160240 222 295 4.05E-8 T 06-07-2017 SMD11_RS20735 bdbe508bd9bc81ba595f017d2cc67c30 322 Pfam PF01545 Cation efflux family 11 218 1.5E-33 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMD11_RS20735 bdbe508bd9bc81ba595f017d2cc67c30 322 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 8 292 8.3E-41 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMD11_RS20735 bdbe508bd9bc81ba595f017d2cc67c30 322 Gene3D G3DSA:1.20.1510.10 8 217 1.4E-32 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain SMD11_RS12625 630f82e161a79a6adb1cde10782cbcce 188 Gene3D G3DSA:3.40.50.880 1 184 1.1E-50 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS12625 630f82e161a79a6adb1cde10782cbcce 188 SUPERFAMILY SSF52317 1 181 3.17E-50 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS12625 630f82e161a79a6adb1cde10782cbcce 188 Pfam PF01965 DJ-1/PfpI family 3 178 6.8E-47 T 06-07-2017 IPR002818 DJ-1/PfpI SMD11_RS12625 630f82e161a79a6adb1cde10782cbcce 188 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 3 180 3.7E-50 T 06-07-2017 IPR006286 Peptidase C56, PfpI SMD11_RS19960 34cf328fd09d1ee6fc070802bd3f7bce 355 SUPERFAMILY SSF52038 261 327 1.31E-9 T 06-07-2017 IPR000468 Barstar (barnase inhibitor) SMD11_RS19960 34cf328fd09d1ee6fc070802bd3f7bce 355 Pfam PF01337 Barstar (barnase inhibitor) 263 325 2.7E-7 T 06-07-2017 IPR000468 Barstar (barnase inhibitor) SMD11_RS19960 34cf328fd09d1ee6fc070802bd3f7bce 355 Gene3D G3DSA:3.30.370.10 261 332 1.4E-9 T 06-07-2017 IPR000468 Barstar (barnase inhibitor) SMD11_RS20000 97be82ea8d65e44d6aeb71b24f7d3308 398 Gene3D G3DSA:2.40.10.10 284 383 1.1E-11 T 06-07-2017 SMD11_RS20000 97be82ea8d65e44d6aeb71b24f7d3308 398 Pfam PF02674 Colicin V production protein 4 146 2.9E-12 T 06-07-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 SMD11_RS20000 97be82ea8d65e44d6aeb71b24f7d3308 398 SUPERFAMILY SSF50494 192 380 2.03E-32 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS20000 97be82ea8d65e44d6aeb71b24f7d3308 398 Gene3D G3DSA:2.40.10.10 190 283 1.7E-17 T 06-07-2017 SMD11_RS20000 97be82ea8d65e44d6aeb71b24f7d3308 398 PRINTS PR00834 HtrA/DegQ protease family signature 227 239 4.7E-10 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS20000 97be82ea8d65e44d6aeb71b24f7d3308 398 PRINTS PR00834 HtrA/DegQ protease family signature 327 344 4.7E-10 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS20000 97be82ea8d65e44d6aeb71b24f7d3308 398 PRINTS PR00834 HtrA/DegQ protease family signature 249 269 4.7E-10 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS20000 97be82ea8d65e44d6aeb71b24f7d3308 398 PRINTS PR00834 HtrA/DegQ protease family signature 287 311 4.7E-10 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS20000 97be82ea8d65e44d6aeb71b24f7d3308 398 Pfam PF13365 Trypsin-like peptidase domain 219 356 1.6E-21 T 06-07-2017 SMD11_RS30680 b7778cd0d42f9e469b2faafaf883799c 202 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 178 34.252 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 SMD11_RS30680 b7778cd0d42f9e469b2faafaf883799c 202 Gene3D G3DSA:3.40.50.1950 1 179 7.3E-75 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD11_RS30680 b7778cd0d42f9e469b2faafaf883799c 202 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 1 176 2.7E-74 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 SMD11_RS30680 b7778cd0d42f9e469b2faafaf883799c 202 SUPERFAMILY SSF52507 1 178 1.57E-60 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD11_RS30680 b7778cd0d42f9e469b2faafaf883799c 202 Pfam PF02441 Flavoprotein 1 122 1.2E-25 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD11_RS27260 edcbf0e43b07d930e3d72a0468dec28e 712 SUPERFAMILY SSF48452 419 585 1.41E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS27260 edcbf0e43b07d930e3d72a0468dec28e 712 Pfam PF05729 NACHT domain 12 150 9.0E-7 T 06-07-2017 SMD11_RS27260 edcbf0e43b07d930e3d72a0468dec28e 712 SUPERFAMILY SSF52540 9 212 7.77E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27260 edcbf0e43b07d930e3d72a0468dec28e 712 Gene3D G3DSA:3.40.50.300 10 123 1.8E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27260 edcbf0e43b07d930e3d72a0468dec28e 712 Gene3D G3DSA:1.25.40.10 479 573 3.8E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS27260 edcbf0e43b07d930e3d72a0468dec28e 712 Gene3D G3DSA:1.25.40.10 374 478 5.8E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS27260 edcbf0e43b07d930e3d72a0468dec28e 712 PRINTS PR00364 Disease resistance protein signature 179 193 3.5E-8 T 06-07-2017 SMD11_RS27260 edcbf0e43b07d930e3d72a0468dec28e 712 PRINTS PR00364 Disease resistance protein signature 82 96 3.5E-8 T 06-07-2017 SMD11_RS27260 edcbf0e43b07d930e3d72a0468dec28e 712 PRINTS PR00364 Disease resistance protein signature 13 28 3.5E-8 T 06-07-2017 SMD11_RS30355 d41a256e96bb15c38e9940c9b7935858 569 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 432 2.2E-71 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS30355 d41a256e96bb15c38e9940c9b7935858 569 Gene3D G3DSA:1.20.1250.20 10 204 9.6E-32 T 06-07-2017 SMD11_RS30355 d41a256e96bb15c38e9940c9b7935858 569 Pfam PF07690 Major Facilitator Superfamily 23 425 3.5E-43 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS30355 d41a256e96bb15c38e9940c9b7935858 569 Gene3D G3DSA:1.20.1250.20 284 433 1.9E-17 T 06-07-2017 SMD11_RS30355 d41a256e96bb15c38e9940c9b7935858 569 Gene3D G3DSA:1.20.1250.20 525 559 1.9E-17 T 06-07-2017 SMD11_RS30355 d41a256e96bb15c38e9940c9b7935858 569 SUPERFAMILY SSF103473 5 205 1.23E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS30355 d41a256e96bb15c38e9940c9b7935858 569 SUPERFAMILY SSF103473 259 434 1.23E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS30355 d41a256e96bb15c38e9940c9b7935858 569 SUPERFAMILY SSF103473 521 551 1.23E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS03055 1532d60b671c081e2c44b8d71aeefb0c 345 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 70 81 4.3E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS03055 1532d60b671c081e2c44b8d71aeefb0c 345 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 91 102 4.3E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS03055 1532d60b671c081e2c44b8d71aeefb0c 345 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 81 91 4.3E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS03055 1532d60b671c081e2c44b8d71aeefb0c 345 Gene3D G3DSA:1.10.10.10 53 134 5.0E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03055 1532d60b671c081e2c44b8d71aeefb0c 345 Gene3D G3DSA:3.40.190.10 225 322 7.0E-25 T 06-07-2017 SMD11_RS03055 1532d60b671c081e2c44b8d71aeefb0c 345 Pfam PF03466 LysR substrate binding domain 139 341 1.1E-30 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS03055 1532d60b671c081e2c44b8d71aeefb0c 345 SUPERFAMILY SSF53850 140 341 4.34E-27 T 06-07-2017 SMD11_RS03055 1532d60b671c081e2c44b8d71aeefb0c 345 SUPERFAMILY SSF46785 50 151 3.78E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03055 1532d60b671c081e2c44b8d71aeefb0c 345 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 55 113 7.5E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS03055 1532d60b671c081e2c44b8d71aeefb0c 345 Gene3D G3DSA:3.40.190.10 140 224 3.6E-19 T 06-07-2017 SMD11_RS27225 404a8896ed9edd6028e37130fc279e15 273 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 125 140 2.5E-5 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD11_RS27225 404a8896ed9edd6028e37130fc279e15 273 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 199 214 2.5E-5 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD11_RS27225 404a8896ed9edd6028e37130fc279e15 273 Gene3D G3DSA:2.40.100.10 111 270 7.8E-35 T 06-07-2017 IPR029000 Cyclophilin-like domain SMD11_RS27225 404a8896ed9edd6028e37130fc279e15 273 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 113 268 1.0E-25 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD11_RS27225 404a8896ed9edd6028e37130fc279e15 273 SUPERFAMILY SSF50891 112 270 7.6E-34 T 06-07-2017 IPR029000 Cyclophilin-like domain SMD11_RS33520 7812a08f133400757533c442e8563ee3 422 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 275 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS33520 7812a08f133400757533c442e8563ee3 422 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 6 421 8.6E-145 T 06-07-2017 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 SMD11_RS33520 7812a08f133400757533c442e8563ee3 422 SUPERFAMILY SSF53383 12 419 4.17E-110 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS33520 7812a08f133400757533c442e8563ee3 422 Pfam PF00202 Aminotransferase class-III 27 417 2.1E-78 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS33520 7812a08f133400757533c442e8563ee3 422 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 10 419 2.6E-200 T 06-07-2017 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 SMD11_RS33520 7812a08f133400757533c442e8563ee3 422 Gene3D G3DSA:3.40.640.10 62 318 7.8E-63 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS33520 7812a08f133400757533c442e8563ee3 422 Gene3D G3DSA:3.90.1150.10 21 61 1.2E-29 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS33520 7812a08f133400757533c442e8563ee3 422 Gene3D G3DSA:3.90.1150.10 324 420 1.2E-29 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS00810 4fbb2b90ecfd202a1c046e55111b9e72 674 Pfam PF06276 Ferric iron reductase FhuF-like transporter 503 641 1.6E-17 T 06-07-2017 IPR022770 Ferric iron reductase FhuF domain SMD11_RS00810 4fbb2b90ecfd202a1c046e55111b9e72 674 Pfam PF04183 IucA / IucC family 217 461 5.9E-36 T 06-07-2017 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 SMD11_RS34335 0cdc7903b31b2fef1f48ad2a4cded819 409 Pfam PF00501 AMP-binding enzyme 15 409 5.7E-92 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS34335 0cdc7903b31b2fef1f48ad2a4cded819 409 SUPERFAMILY SSF56801 2 409 3.92E-105 T 06-07-2017 SMD11_RS34335 0cdc7903b31b2fef1f48ad2a4cded819 409 Gene3D G3DSA:2.30.38.10 328 400 2.6E-25 T 06-07-2017 SMD11_RS34335 0cdc7903b31b2fef1f48ad2a4cded819 409 ProSitePatterns PS00455 Putative AMP-binding domain signature. 164 175 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS34335 0cdc7903b31b2fef1f48ad2a4cded819 409 Gene3D G3DSA:3.40.50.980 169 320 2.6E-36 T 06-07-2017 SMD11_RS34335 0cdc7903b31b2fef1f48ad2a4cded819 409 Gene3D G3DSA:3.40.50.980 2 168 1.3E-35 T 06-07-2017 SMD11_RS06800 305f9910ad2ba1aeb91f0f05f05a0e4d 334 Gene3D G3DSA:1.10.101.10 214 284 9.0E-5 T 06-07-2017 IPR002477 Peptidoglycan binding-like SMD11_RS06800 305f9910ad2ba1aeb91f0f05f05a0e4d 334 Pfam PF01476 LysM domain 291 334 3.6E-12 T 06-07-2017 IPR018392 LysM domain SMD11_RS06800 305f9910ad2ba1aeb91f0f05f05a0e4d 334 SMART SM00257 289 334 1.6E-13 T 06-07-2017 IPR018392 LysM domain SMD11_RS06800 305f9910ad2ba1aeb91f0f05f05a0e4d 334 Gene3D G3DSA:3.10.350.10 289 334 2.9E-11 T 06-07-2017 IPR018392 LysM domain SMD11_RS06800 305f9910ad2ba1aeb91f0f05f05a0e4d 334 Pfam PF05257 CHAP domain 40 117 1.4E-6 T 06-07-2017 IPR007921 CHAP domain SMD11_RS06800 305f9910ad2ba1aeb91f0f05f05a0e4d 334 SUPERFAMILY SSF54106 288 334 5.62E-8 T 06-07-2017 IPR018392 LysM domain SMD11_RS14215 cb481883f747703ccc70e4c89d5e0fb5 416 Pfam PF13439 Glycosyltransferase Family 4 17 198 7.0E-33 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 SMD11_RS14215 cb481883f747703ccc70e4c89d5e0fb5 416 Pfam PF00534 Glycosyl transferases group 1 209 381 1.4E-32 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 SMD11_RS14215 cb481883f747703ccc70e4c89d5e0fb5 416 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 1 408 50.65 T 06-07-2017 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMD11_RS14215 cb481883f747703ccc70e4c89d5e0fb5 416 Gene3D G3DSA:3.40.50.2000 178 382 4.7E-40 T 06-07-2017 SMD11_RS14215 cb481883f747703ccc70e4c89d5e0fb5 416 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 1 405 2.2E-198 T 06-07-2017 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMD11_RS14215 cb481883f747703ccc70e4c89d5e0fb5 416 SUPERFAMILY SSF53756 15 406 1.08E-85 T 06-07-2017 SMD11_RS17060 66eb1acd19fbc52c2c7eb7d7117e3a43 284 SUPERFAMILY SSF49879 164 280 5.16E-23 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 SMD11_RS17060 66eb1acd19fbc52c2c7eb7d7117e3a43 284 Pfam PF12401 Protein of unknown function (DUF2662) 4 118 1.8E-41 T 06-07-2017 IPR022128 Protein of unknown function DUF3662 SMD11_RS17060 66eb1acd19fbc52c2c7eb7d7117e3a43 284 Gene3D G3DSA:2.60.200.20 200 280 9.8E-25 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS17060 66eb1acd19fbc52c2c7eb7d7117e3a43 284 Pfam PF00498 FHA domain 212 273 7.2E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS17060 66eb1acd19fbc52c2c7eb7d7117e3a43 284 SMART SM00240 210 259 8.0E-12 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS19280 35c28b87e140b2fffb6a6bf2b95dd3af 421 Gene3D G3DSA:3.40.50.720 233 413 3.5E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19280 35c28b87e140b2fffb6a6bf2b95dd3af 421 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 292 8.4E-25 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD11_RS19280 35c28b87e140b2fffb6a6bf2b95dd3af 421 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 410 6.0E-104 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMD11_RS19280 35c28b87e140b2fffb6a6bf2b95dd3af 421 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 5 32 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SMD11_RS19280 35c28b87e140b2fffb6a6bf2b95dd3af 421 Gene3D G3DSA:3.40.50.720 6 196 9.7E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19280 35c28b87e140b2fffb6a6bf2b95dd3af 421 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 321 412 1.0E-14 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD11_RS19280 35c28b87e140b2fffb6a6bf2b95dd3af 421 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 184 2.9E-27 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD11_RS19280 35c28b87e140b2fffb6a6bf2b95dd3af 421 SUPERFAMILY SSF51735 6 196 2.03E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19280 35c28b87e140b2fffb6a6bf2b95dd3af 421 PIRSF PIRSF000124 3 420 2.7E-47 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMD11_RS19280 35c28b87e140b2fffb6a6bf2b95dd3af 421 SUPERFAMILY SSF48179 202 299 1.34E-24 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS19280 35c28b87e140b2fffb6a6bf2b95dd3af 421 SMART SM00984 320 415 7.0E-20 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD11_RS19280 35c28b87e140b2fffb6a6bf2b95dd3af 421 PIRSF PIRSF500136 1 421 6.2E-130 T 06-07-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 SMD11_RS19280 35c28b87e140b2fffb6a6bf2b95dd3af 421 SUPERFAMILY SSF52413 305 414 4.32E-21 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD11_RS17660 d9544c2d515b006afe54a8498fde442d 165 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 123 138 4.1E-38 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD11_RS17660 d9544c2d515b006afe54a8498fde442d 165 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 23 38 4.1E-38 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD11_RS17660 d9544c2d515b006afe54a8498fde442d 165 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 110 122 4.1E-38 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD11_RS17660 d9544c2d515b006afe54a8498fde442d 165 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 95 110 4.1E-38 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD11_RS17660 d9544c2d515b006afe54a8498fde442d 165 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 52 64 4.1E-38 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD11_RS17660 d9544c2d515b006afe54a8498fde442d 165 PIRSF PIRSF001467 1 165 8.6E-76 T 06-07-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 SMD11_RS17660 d9544c2d515b006afe54a8498fde442d 165 SUPERFAMILY SSF50891 3 163 5.99E-67 T 06-07-2017 IPR029000 Cyclophilin-like domain SMD11_RS17660 d9544c2d515b006afe54a8498fde442d 165 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 160 4.0E-45 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD11_RS17660 d9544c2d515b006afe54a8498fde442d 165 Gene3D G3DSA:2.40.100.10 3 162 2.2E-70 T 06-07-2017 IPR029000 Cyclophilin-like domain SMD11_RS17660 d9544c2d515b006afe54a8498fde442d 165 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 47 64 - T 06-07-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 SMD11_RS25805 cf58db924931fa1b8920ae3c3c4787b4 681 SUPERFAMILY SSF48452 444 557 8.22E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS25805 cf58db924931fa1b8920ae3c3c4787b4 681 SUPERFAMILY SSF48452 524 628 6.57E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS25805 cf58db924931fa1b8920ae3c3c4787b4 681 SMART SM00028 448 481 120.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS25805 cf58db924931fa1b8920ae3c3c4787b4 681 SMART SM00028 568 601 3.8 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS25805 cf58db924931fa1b8920ae3c3c4787b4 681 SMART SM00028 528 561 10.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS25805 cf58db924931fa1b8920ae3c3c4787b4 681 SMART SM00028 488 521 4.7 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS25805 cf58db924931fa1b8920ae3c3c4787b4 681 Pfam PF00931 NB-ARC domain 20 204 2.0E-11 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 SMD11_RS25805 cf58db924931fa1b8920ae3c3c4787b4 681 Pfam PF13424 Tetratricopeptide repeat 448 518 4.5E-10 T 06-07-2017 SMD11_RS25805 cf58db924931fa1b8920ae3c3c4787b4 681 Pfam PF13424 Tetratricopeptide repeat 527 599 3.3E-9 T 06-07-2017 SMD11_RS25805 cf58db924931fa1b8920ae3c3c4787b4 681 Gene3D G3DSA:1.25.40.10 446 627 9.1E-23 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS25805 cf58db924931fa1b8920ae3c3c4787b4 681 Gene3D G3DSA:3.40.50.300 24 116 9.8E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25805 cf58db924931fa1b8920ae3c3c4787b4 681 SUPERFAMILY SSF52540 21 248 4.92E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25805 cf58db924931fa1b8920ae3c3c4787b4 681 PRINTS PR00364 Disease resistance protein signature 187 201 6.4E-6 T 06-07-2017 SMD11_RS25805 cf58db924931fa1b8920ae3c3c4787b4 681 PRINTS PR00364 Disease resistance protein signature 102 116 6.4E-6 T 06-07-2017 SMD11_RS25805 cf58db924931fa1b8920ae3c3c4787b4 681 PRINTS PR00364 Disease resistance protein signature 26 41 6.4E-6 T 06-07-2017 SMD11_RS08515 b4e5bbfcb132be7f4970e74037b0cca3 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 1.2E-8 T 06-07-2017 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 SMD11_RS08515 b4e5bbfcb132be7f4970e74037b0cca3 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 7 29 8.0E-9 T 06-07-2017 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 SMD11_RS11035 f1fd703614a5f480ba5623fd8a91f279 234 SUPERFAMILY SSF53335 19 216 2.41E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS11035 f1fd703614a5f480ba5623fd8a91f279 234 Gene3D G3DSA:3.40.50.150 58 204 2.4E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS05580 90d12549f5032f3bf6404a892b7d19f2 296 Pfam PF05368 NmrA-like family 12 238 7.4E-48 T 06-07-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 SMD11_RS05580 90d12549f5032f3bf6404a892b7d19f2 296 Gene3D G3DSA:3.40.50.720 10 232 1.8E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05580 90d12549f5032f3bf6404a892b7d19f2 296 SUPERFAMILY SSF51735 11 265 6.43E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 Pfam PF00069 Protein kinase domain 222 386 5.4E-9 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 SUPERFAMILY SSF56112 440 470 4.25E-27 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 SUPERFAMILY SSF56112 206 384 4.25E-27 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 SUPERFAMILY SSF158745 645 991 3.92E-48 T 06-07-2017 SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 Gene3D G3DSA:1.10.510.10 283 386 8.6E-16 T 06-07-2017 SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 Gene3D G3DSA:1.10.510.10 438 470 8.6E-16 T 06-07-2017 SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 Gene3D G3DSA:1.50.10.10 867 951 2.0E-4 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 Gene3D G3DSA:3.30.200.20 206 282 1.2E-5 T 06-07-2017 SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 Pfam PF05147 Lanthionine synthetase C-like protein 648 990 1.8E-34 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 SMART SM00220 210 526 1.9E-7 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 PRINTS PR01950 LanC-like protein superfamily signature 969 986 4.0E-12 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 PRINTS PR01950 LanC-like protein superfamily signature 738 753 4.0E-12 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 PRINTS PR01950 LanC-like protein superfamily signature 865 885 4.0E-12 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 PRINTS PR01950 LanC-like protein superfamily signature 911 924 4.0E-12 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 PRINTS PR01950 LanC-like protein superfamily signature 803 819 4.0E-12 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS31700 55e83e354ac5cb83ad399fdcaadefe32 1042 SMART SM01260 643 998 3.3E-41 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS10880 64171fd41f879986fd825f078e5d8724 430 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 13 131 1.9E-21 T 06-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 SMD11_RS10880 64171fd41f879986fd825f078e5d8724 430 Gene3D G3DSA:3.30.360.10 151 303 4.2E-55 T 06-07-2017 SMD11_RS10880 64171fd41f879986fd825f078e5d8724 430 Gene3D G3DSA:3.30.70.260 351 421 4.7E-11 T 06-07-2017 SMD11_RS10880 64171fd41f879986fd825f078e5d8724 430 SUPERFAMILY SSF55021 350 422 7.64E-15 T 06-07-2017 SMD11_RS10880 64171fd41f879986fd825f078e5d8724 430 Gene3D G3DSA:3.40.50.720 2 150 6.4E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10880 64171fd41f879986fd825f078e5d8724 430 Pfam PF01842 ACT domain 354 416 8.5E-14 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 SMD11_RS10880 64171fd41f879986fd825f078e5d8724 430 Pfam PF00742 Homoserine dehydrogenase 139 319 5.8E-67 T 06-07-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SMD11_RS10880 64171fd41f879986fd825f078e5d8724 430 SUPERFAMILY SSF55347 139 306 9.81E-53 T 06-07-2017 SMD11_RS10880 64171fd41f879986fd825f078e5d8724 430 PIRSF PIRSF000098 4 430 1.8E-156 T 06-07-2017 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SMD11_RS10880 64171fd41f879986fd825f078e5d8724 430 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 185 207 - T 06-07-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SMD11_RS10880 64171fd41f879986fd825f078e5d8724 430 SUPERFAMILY SSF51735 5 160 1.36E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS07450 6de59ef292d9e0981511fac75b42697c 357 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 19 354 1.2E-131 T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SMD11_RS07450 6de59ef292d9e0981511fac75b42697c 357 SUPERFAMILY SSF51726 21 355 4.84E-110 T 06-07-2017 SMD11_RS07450 6de59ef292d9e0981511fac75b42697c 357 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 19 355 48.259 T 06-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SMD11_RS07450 6de59ef292d9e0981511fac75b42697c 357 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 35 44 - T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SMD11_RS07450 6de59ef292d9e0981511fac75b42697c 357 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 152 168 - T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SMD11_RS07450 6de59ef292d9e0981511fac75b42697c 357 Gene3D G3DSA:3.20.20.210 18 355 1.9E-147 T 06-07-2017 SMD11_RS07450 6de59ef292d9e0981511fac75b42697c 357 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 22 353 8.6E-125 T 06-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 SMD11_RS30745 a06feed152348ec03df0a3476e414c0f 495 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 372 478 2.2E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS30745 a06feed152348ec03df0a3476e414c0f 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 459 2.6E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS30745 a06feed152348ec03df0a3476e414c0f 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 420 2.6E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS30745 a06feed152348ec03df0a3476e414c0f 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 478 2.6E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS30745 a06feed152348ec03df0a3476e414c0f 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 434 2.6E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS30745 a06feed152348ec03df0a3476e414c0f 495 Gene3D G3DSA:3.30.565.10 338 482 1.1E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS30745 a06feed152348ec03df0a3476e414c0f 495 SMART SM00387 371 481 6.2E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS30745 a06feed152348ec03df0a3476e414c0f 495 Pfam PF00672 HAMP domain 194 263 5.9E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS30745 a06feed152348ec03df0a3476e414c0f 495 SUPERFAMILY SSF47384 251 329 1.43E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS30745 a06feed152348ec03df0a3476e414c0f 495 Gene3D G3DSA:1.10.287.130 260 325 1.6E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS30745 a06feed152348ec03df0a3476e414c0f 495 SUPERFAMILY SSF55874 319 482 3.27E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS30745 a06feed152348ec03df0a3476e414c0f 495 SMART SM00388 268 329 4.7E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS30745 a06feed152348ec03df0a3476e414c0f 495 Pfam PF00512 His Kinase A (phospho-acceptor) domain 269 329 3.9E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS30745 a06feed152348ec03df0a3476e414c0f 495 SMART SM00304 213 267 1.1E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS14050 69dc8df776d96e643b546ec0f58d2a03 381 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 283 374 1.7E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14050 69dc8df776d96e643b546ec0f58d2a03 381 SMART SM00387 279 376 2.2E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14050 69dc8df776d96e643b546ec0f58d2a03 381 Gene3D G3DSA:3.30.565.10 264 376 4.1E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14050 69dc8df776d96e643b546ec0f58d2a03 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 336 354 3.4E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS14050 69dc8df776d96e643b546ec0f58d2a03 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 315 329 3.4E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS14050 69dc8df776d96e643b546ec0f58d2a03 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 373 3.4E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS14050 69dc8df776d96e643b546ec0f58d2a03 381 PIRSF PIRSF037434 1 381 9.7E-130 T 06-07-2017 IPR017205 Signal transduction histidine kinase, ChrS SMD11_RS14050 69dc8df776d96e643b546ec0f58d2a03 381 Pfam PF07730 Histidine kinase 171 237 9.8E-18 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS14050 69dc8df776d96e643b546ec0f58d2a03 381 SUPERFAMILY SSF55874 263 373 4.45E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS22770 f229ae074285b52452a7d369e6f1bd2c 165 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 4.5E-32 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SMD11_RS22770 f229ae074285b52452a7d369e6f1bd2c 165 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 157 22.104 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SMD11_RS22770 f229ae074285b52452a7d369e6f1bd2c 165 SUPERFAMILY SSF55486 3 149 1.32E-37 T 06-07-2017 SMD11_RS22770 f229ae074285b52452a7d369e6f1bd2c 165 Gene3D G3DSA:3.40.390.30 5 154 3.1E-43 T 06-07-2017 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 SMD11_RS22770 f229ae074285b52452a7d369e6f1bd2c 165 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 119 129 - T 06-07-2017 IPR020549 Endoribonuclease YbeY, conserved site SMD11_RS22770 f229ae074285b52452a7d369e6f1bd2c 165 Pfam PF02130 Uncharacterized protein family UPF0054 16 147 3.0E-37 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SMD11_RS22375 2fd02248df8b97a07fabffceef5bb2b2 392 SUPERFAMILY SSF55874 200 365 2.75E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS22375 2fd02248df8b97a07fabffceef5bb2b2 392 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 255 365 1.6E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS22375 2fd02248df8b97a07fabffceef5bb2b2 392 SUPERFAMILY SSF55785 5 120 3.14E-5 T 06-07-2017 IPR000014 PAS domain SMD11_RS22375 2fd02248df8b97a07fabffceef5bb2b2 392 SUPERFAMILY SSF47384 128 208 1.24E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS22375 2fd02248df8b97a07fabffceef5bb2b2 392 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 364 9.9E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS22375 2fd02248df8b97a07fabffceef5bb2b2 392 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 320 9.9E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS22375 2fd02248df8b97a07fabffceef5bb2b2 392 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 345 9.9E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS22375 2fd02248df8b97a07fabffceef5bb2b2 392 PRINTS PR00344 Bacterial sensor protein C-terminal signature 292 306 9.9E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS22375 2fd02248df8b97a07fabffceef5bb2b2 392 Gene3D G3DSA:1.10.287.130 147 195 3.5E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS22375 2fd02248df8b97a07fabffceef5bb2b2 392 Gene3D G3DSA:3.30.450.20 117 146 1.1E-4 T 06-07-2017 SMD11_RS22375 2fd02248df8b97a07fabffceef5bb2b2 392 Gene3D G3DSA:3.30.565.10 196 367 4.4E-43 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS22375 2fd02248df8b97a07fabffceef5bb2b2 392 Pfam PF00512 His Kinase A (phospho-acceptor) domain 143 209 5.0E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS22375 2fd02248df8b97a07fabffceef5bb2b2 392 SMART SM00387 255 367 6.8E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS22375 2fd02248df8b97a07fabffceef5bb2b2 392 SMART SM00388 142 210 1.3E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS22375 2fd02248df8b97a07fabffceef5bb2b2 392 Gene3D G3DSA:3.30.450.20 4 116 1.9E-8 T 06-07-2017 SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 SUPERFAMILY SSF52540 5 221 3.6E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 SUPERFAMILY SSF54980 427 541 3.96E-27 T 06-07-2017 IPR009022 Elongation factor G, III-V domain SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 Pfam PF00679 Elongation factor G C-terminus 426 508 5.4E-20 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 Gene3D G3DSA:3.40.50.300 4 221 1.4E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 Gene3D G3DSA:2.40.30.10 222 319 8.8E-29 T 06-07-2017 SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 Gene3D G3DSA:3.30.70.240 431 509 2.7E-30 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 626 7.8E-287 T 06-07-2017 IPR006298 GTP-binding protein TypA GO:0005525 SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 Pfam PF03144 Elongation factor Tu domain 2 235 305 3.0E-10 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 SUPERFAMILY SSF50447 211 315 2.04E-30 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 SUPERFAMILY SSF50447 162 184 2.04E-30 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 Gene3D G3DSA:2.40.50.250 511 605 1.4E-37 T 06-07-2017 SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 SUPERFAMILY SSF54980 319 416 1.53E-9 T 06-07-2017 IPR009022 Elongation factor G, III-V domain SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 Gene3D G3DSA:3.30.70.870 320 430 6.1E-33 T 06-07-2017 SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 PRINTS PR00315 GTP-binding elongation factor signature 81 91 1.5E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 PRINTS PR00315 GTP-binding elongation factor signature 55 63 1.5E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 PRINTS PR00315 GTP-binding elongation factor signature 133 142 1.5E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.5E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 PRINTS PR00315 GTP-binding elongation factor signature 97 108 1.5E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 161 8.9E-22 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 SMD11_RS12035 d1205ce4c7ecc2d8bcf8518be5051e25 634 Pfam PF00009 Elongation factor Tu GTP binding domain 6 211 3.1E-51 T 06-07-2017 SMD11_RS24465 8fdf4fc5360d6463fd17f26951be3f76 340 Gene3D G3DSA:1.10.8.300 209 315 1.0E-34 T 06-07-2017 SMD11_RS24465 8fdf4fc5360d6463fd17f26951be3f76 340 PIRSF PIRSF002849 2 321 3.4E-130 T 06-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted SMD11_RS24465 8fdf4fc5360d6463fd17f26951be3f76 340 Gene3D G3DSA:3.40.50.300 33 193 3.5E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24465 8fdf4fc5360d6463fd17f26951be3f76 340 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 47 176 4.7E-65 T 06-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 SMD11_RS24465 8fdf4fc5360d6463fd17f26951be3f76 340 SUPERFAMILY SSF52540 17 291 3.28E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07325 0a4281ad0682580a737a9324305390a8 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07325 0a4281ad0682580a737a9324305390a8 209 SUPERFAMILY SSF46894 135 206 2.93E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS07325 0a4281ad0682580a737a9324305390a8 209 Gene3D G3DSA:1.10.10.10 123 206 1.7E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07325 0a4281ad0682580a737a9324305390a8 209 Pfam PF00072 Response regulator receiver domain 4 117 1.5E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS07325 0a4281ad0682580a737a9324305390a8 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 197 1.4E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07325 0a4281ad0682580a737a9324305390a8 209 SUPERFAMILY SSF52172 2 133 3.42E-31 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS07325 0a4281ad0682580a737a9324305390a8 209 Gene3D G3DSA:3.40.50.2300 2 122 1.1E-36 T 06-07-2017 SMD11_RS07325 0a4281ad0682580a737a9324305390a8 209 SMART SM00448 2 117 2.8E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS07325 0a4281ad0682580a737a9324305390a8 209 SMART SM00421 143 200 2.9E-22 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07325 0a4281ad0682580a737a9324305390a8 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 1.8E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07325 0a4281ad0682580a737a9324305390a8 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 1.8E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07325 0a4281ad0682580a737a9324305390a8 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 1.8E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS32735 bece02200e1cee9494b480e5b2a8b2f0 276 SUPERFAMILY SSF52402 9 274 5.24E-75 T 06-07-2017 SMD11_RS32735 bece02200e1cee9494b480e5b2a8b2f0 276 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 23 276 32.627 T 06-07-2017 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 SMD11_RS32735 bece02200e1cee9494b480e5b2a8b2f0 276 Pfam PF02540 NAD synthase 29 273 8.3E-64 T 06-07-2017 IPR022310 NAD/GMP synthase SMD11_RS32735 bece02200e1cee9494b480e5b2a8b2f0 276 TIGRFAM TIGR00552 nadE: NAD+ synthetase 25 274 3.9E-63 T 06-07-2017 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 SMD11_RS32735 bece02200e1cee9494b480e5b2a8b2f0 276 Gene3D G3DSA:3.40.50.620 10 274 3.6E-70 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS09250 f547618b92be0b93d049217762efa641 329 SUPERFAMILY SSF54814 259 324 1.31E-15 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 SMD11_RS09250 f547618b92be0b93d049217762efa641 329 Pfam PF00575 S1 RNA binding domain 114 176 4.9E-5 T 06-07-2017 IPR003029 S1 domain GO:0003676 SMD11_RS09250 f547618b92be0b93d049217762efa641 329 Pfam PF13184 NusA-like KH domain 210 278 3.3E-26 T 06-07-2017 IPR025249 KH domain, NusA-like GO:0003723 SMD11_RS09250 f547618b92be0b93d049217762efa641 329 Gene3D G3DSA:3.30.300.20 258 327 3.3E-29 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta SMD11_RS09250 f547618b92be0b93d049217762efa641 329 SUPERFAMILY SSF50249 112 179 2.37E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS09250 f547618b92be0b93d049217762efa641 329 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 322 8.9E-105 T 06-07-2017 IPR010213 Transcription termination factor NusA GO:0003723 SMD11_RS09250 f547618b92be0b93d049217762efa641 329 Gene3D G3DSA:3.30.1480.10 3 102 2.1E-30 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SMD11_RS09250 f547618b92be0b93d049217762efa641 329 SUPERFAMILY SSF54814 180 258 1.7E-27 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 SMD11_RS09250 f547618b92be0b93d049217762efa641 329 Gene3D G3DSA:3.30.300.20 179 257 3.5E-33 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta SMD11_RS09250 f547618b92be0b93d049217762efa641 329 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 328 25.86 T 06-07-2017 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 SMD11_RS09250 f547618b92be0b93d049217762efa641 329 Pfam PF08529 NusA N-terminal domain 6 62 3.9E-9 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SMD11_RS09250 f547618b92be0b93d049217762efa641 329 Pfam PF08529 NusA N-terminal domain 63 103 1.1E-7 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SMD11_RS09250 f547618b92be0b93d049217762efa641 329 SUPERFAMILY SSF69705 3 102 3.53E-27 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SMD11_RS09250 f547618b92be0b93d049217762efa641 329 SMART SM00316 113 178 1.8E-4 T 06-07-2017 IPR022967 RNA-binding domain, S1 SMD11_RS09250 f547618b92be0b93d049217762efa641 329 Gene3D G3DSA:2.40.50.140 109 178 1.1E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS07420 c3fcf0895d903bdaca2da37f192c4b29 397 PIRSF PIRSF000429 2 397 3.5E-125 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS07420 c3fcf0895d903bdaca2da37f192c4b29 397 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 396 5.7E-132 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS07420 c3fcf0895d903bdaca2da37f192c4b29 397 SUPERFAMILY SSF53901 275 397 2.11E-33 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07420 c3fcf0895d903bdaca2da37f192c4b29 397 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMD11_RS07420 c3fcf0895d903bdaca2da37f192c4b29 397 Gene3D G3DSA:3.40.47.10 204 280 9.8E-68 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07420 c3fcf0895d903bdaca2da37f192c4b29 397 Gene3D G3DSA:3.40.47.10 7 129 9.8E-68 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07420 c3fcf0895d903bdaca2da37f192c4b29 397 Gene3D G3DSA:3.40.47.10 164 203 2.7E-47 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07420 c3fcf0895d903bdaca2da37f192c4b29 397 Gene3D G3DSA:3.40.47.10 281 396 2.7E-47 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07420 c3fcf0895d903bdaca2da37f192c4b29 397 Pfam PF02803 Thiolase, C-terminal domain 275 397 7.0E-36 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD11_RS07420 c3fcf0895d903bdaca2da37f192c4b29 397 SUPERFAMILY SSF53901 7 273 8.08E-78 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07420 c3fcf0895d903bdaca2da37f192c4b29 397 ProSitePatterns PS00099 Thiolases active site. 379 392 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SMD11_RS07420 c3fcf0895d903bdaca2da37f192c4b29 397 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 90 108 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 SMD11_RS07420 c3fcf0895d903bdaca2da37f192c4b29 397 Pfam PF00108 Thiolase, N-terminal domain 8 267 1.9E-72 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD11_RS18950 a22edbf57378278d116f91997b168218 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 26.235 T 06-07-2017 IPR023053 Ribosomal protein S14, type Z SMD11_RS18950 a22edbf57378278d116f91997b168218 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 06-07-2017 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18950 a22edbf57378278d116f91997b168218 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 2.0E-24 T 06-07-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18950 a22edbf57378278d116f91997b168218 61 SUPERFAMILY SSF57716 3 61 6.42E-22 T 06-07-2017 SMD11_RS18950 a22edbf57378278d116f91997b168218 61 Gene3D G3DSA:4.10.830.10 1 61 2.2E-28 T 06-07-2017 SMD11_RS17510 6121c805f989ca313aeea256347c9abf 404 SUPERFAMILY SSF54001 301 367 4.46E-7 T 06-07-2017 SMD11_RS17510 6121c805f989ca313aeea256347c9abf 404 Gene3D G3DSA:3.90.1720.10 314 394 4.4E-7 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS17510 6121c805f989ca313aeea256347c9abf 404 Pfam PF00877 NlpC/P60 family 311 367 1.6E-4 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS23200 018954ee70ef61b92a1467d70dea8782 321 Pfam PF00698 Acyl transferase domain 5 285 3.8E-15 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS23200 018954ee70ef61b92a1467d70dea8782 321 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 308 1.1E-16 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS23200 018954ee70ef61b92a1467d70dea8782 321 Gene3D G3DSA:3.30.70.250 126 191 3.7E-22 T 06-07-2017 SMD11_RS23200 018954ee70ef61b92a1467d70dea8782 321 SUPERFAMILY SSF52151 185 307 1.26E-61 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS23200 018954ee70ef61b92a1467d70dea8782 321 SUPERFAMILY SSF52151 2 122 1.26E-61 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS23200 018954ee70ef61b92a1467d70dea8782 321 Gene3D G3DSA:3.40.366.10 2 122 6.3E-49 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS23200 018954ee70ef61b92a1467d70dea8782 321 Gene3D G3DSA:3.40.366.10 192 299 6.3E-49 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS23200 018954ee70ef61b92a1467d70dea8782 321 SUPERFAMILY SSF55048 130 187 4.05E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 193 206 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 362 388 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 SUPERFAMILY SSF88659 300 398 2.62E-28 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 PRINTS PR00046 Major sigma-70 factor signature 341 353 7.4E-30 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 PRINTS PR00046 Major sigma-70 factor signature 193 206 7.4E-30 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 PRINTS PR00046 Major sigma-70 factor signature 362 377 7.4E-30 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 PRINTS PR00046 Major sigma-70 factor signature 217 225 7.4E-30 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 PRINTS PR00046 Major sigma-70 factor signature 377 388 7.4E-30 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 Pfam PF04539 Sigma-70 region 3 248 324 4.6E-27 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 Gene3D G3DSA:1.10.10.10 242 293 4.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 Gene3D G3DSA:1.10.10.10 331 402 2.7E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 SUPERFAMILY SSF88659 242 315 1.99E-19 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 165 390 1.1E-36 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 Gene3D G3DSA:1.10.601.10 88 238 5.9E-62 T 06-07-2017 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 Pfam PF04545 Sigma-70, region 4 337 390 6.8E-20 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 SUPERFAMILY SSF88946 101 239 1.14E-50 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 Pfam PF00140 Sigma-70 factor, region 1.2 104 137 1.1E-14 T 06-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23035 19f3436b35fde9ce6ed1fe2d1e3ec59c 402 Pfam PF04542 Sigma-70 region 2 169 238 5.4E-23 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS04415 a3a072c90b19109c6e67142f301ecd8a 306 Gene3D G3DSA:3.40.50.2300 29 145 3.7E-38 T 06-07-2017 SMD11_RS04415 a3a072c90b19109c6e67142f301ecd8a 306 Gene3D G3DSA:3.40.50.2300 146 304 8.8E-59 T 06-07-2017 SMD11_RS04415 a3a072c90b19109c6e67142f301ecd8a 306 SUPERFAMILY SSF53822 19 304 2.91E-89 T 06-07-2017 IPR028082 Periplasmic binding protein-like I SMD11_RS04415 a3a072c90b19109c6e67142f301ecd8a 306 Pfam PF13407 Periplasmic binding protein domain 32 283 5.8E-62 T 06-07-2017 IPR025997 Periplasmic binding protein SMD11_RS20055 fa4ea8d4bebca18194a20cda1f241b19 286 Gene3D G3DSA:3.40.1010.10 3 113 3.5E-7 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS20055 fa4ea8d4bebca18194a20cda1f241b19 286 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 6 272 3.6E-61 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD11_RS20055 fa4ea8d4bebca18194a20cda1f241b19 286 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 4 224 32.575 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD11_RS20055 fa4ea8d4bebca18194a20cda1f241b19 286 SUPERFAMILY SSF53790 3 222 8.51E-73 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS20055 fa4ea8d4bebca18194a20cda1f241b19 286 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 207 1.7E-29 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS20055 fa4ea8d4bebca18194a20cda1f241b19 286 PIRSF PIRSF005917 1 280 4.1E-89 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD11_RS20055 fa4ea8d4bebca18194a20cda1f241b19 286 Gene3D G3DSA:3.30.950.10 114 225 8.3E-44 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS02780 c123629a8153625ad981ef4cde049b96 355 Gene3D G3DSA:3.20.20.30 14 266 4.6E-43 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS02780 c123629a8153625ad981ef4cde049b96 355 Gene3D G3DSA:3.20.20.30 303 354 4.6E-43 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS02780 c123629a8153625ad981ef4cde049b96 355 Pfam PF00296 Luciferase-like monooxygenase 13 334 1.3E-29 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS02780 c123629a8153625ad981ef4cde049b96 355 SUPERFAMILY SSF51679 13 350 1.88E-35 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS03005 edf5fe7df0e7d4cfabfb80a90432bc21 412 SUPERFAMILY SSF56801 180 334 2.01E-6 T 06-07-2017 SMD11_RS20315 4892087345d0f1f4ecaad6d26fa9cca5 461 SUPERFAMILY SSF51905 263 347 6.42E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS20315 4892087345d0f1f4ecaad6d26fa9cca5 461 SUPERFAMILY SSF51905 5 175 6.42E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS20315 4892087345d0f1f4ecaad6d26fa9cca5 461 Gene3D G3DSA:3.50.50.60 6 112 8.3E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS20315 4892087345d0f1f4ecaad6d26fa9cca5 461 Gene3D G3DSA:3.50.50.60 270 349 8.3E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS20315 4892087345d0f1f4ecaad6d26fa9cca5 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 336 1.8E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS20315 4892087345d0f1f4ecaad6d26fa9cca5 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.8E-7 T 06-07-2017 SMD11_RS20315 4892087345d0f1f4ecaad6d26fa9cca5 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 1.8E-7 T 06-07-2017 SMD11_RS20315 4892087345d0f1f4ecaad6d26fa9cca5 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 1.8E-7 T 06-07-2017 SMD11_RS20315 4892087345d0f1f4ecaad6d26fa9cca5 461 SUPERFAMILY SSF51905 104 123 2.81E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS20315 4892087345d0f1f4ecaad6d26fa9cca5 461 SUPERFAMILY SSF51905 162 268 2.81E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS20315 4892087345d0f1f4ecaad6d26fa9cca5 461 Gene3D G3DSA:3.50.50.60 113 269 3.2E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29220 f47a713fcd38ca6a676129922bd50e8c 300 Gene3D G3DSA:3.90.25.10 191 289 1.1E-12 T 06-07-2017 SMD11_RS29220 f47a713fcd38ca6a676129922bd50e8c 300 SUPERFAMILY SSF51735 1 289 4.98E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29220 f47a713fcd38ca6a676129922bd50e8c 300 Gene3D G3DSA:3.40.50.720 1 190 2.7E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29220 f47a713fcd38ca6a676129922bd50e8c 300 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 221 2.5E-29 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 SMD11_RS18890 5e596a0fe559224baada57cf6ce08180 216 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 32.739 T 06-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18890 5e596a0fe559224baada57cf6ce08180 216 Pfam PF00573 Ribosomal protein L4/L1 family 17 202 4.4E-64 T 06-07-2017 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 SMD11_RS18890 5e596a0fe559224baada57cf6ce08180 216 SUPERFAMILY SSF52166 1 203 1.83E-74 T 06-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SMD11_RS18890 5e596a0fe559224baada57cf6ce08180 216 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 202 4.4E-70 T 06-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18890 5e596a0fe559224baada57cf6ce08180 216 Gene3D G3DSA:3.40.1370.10 58 202 7.4E-51 T 06-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SMD11_RS25385 a480acc1c885d3a399fd45002a616353 514 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 493 3.5E-132 T 06-07-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 SMD11_RS25385 a480acc1c885d3a399fd45002a616353 514 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 502 170.644 T 06-07-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 SMD11_RS25385 a480acc1c885d3a399fd45002a616353 514 Gene3D G3DSA:3.40.50.300 5 250 6.9E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25385 a480acc1c885d3a399fd45002a616353 514 Gene3D G3DSA:3.40.50.880 275 457 8.8E-40 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS25385 a480acc1c885d3a399fd45002a616353 514 SUPERFAMILY SSF52540 126 254 1.77E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25385 a480acc1c885d3a399fd45002a616353 514 SUPERFAMILY SSF52540 5 97 1.77E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25385 a480acc1c885d3a399fd45002a616353 514 SUPERFAMILY SSF52317 287 438 2.01E-37 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS25385 a480acc1c885d3a399fd45002a616353 514 SUPERFAMILY SSF52317 206 252 2.01E-37 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS25385 a480acc1c885d3a399fd45002a616353 514 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 275 445 4.7E-44 T 06-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 SMD11_RS25385 a480acc1c885d3a399fd45002a616353 514 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 239 6.2E-25 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 SUPERFAMILY SSF47323 586 823 9.16E-52 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 SUPERFAMILY SSF52374 355 584 4.77E-136 T 06-07-2017 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 SUPERFAMILY SSF52374 18 209 4.77E-136 T 06-07-2017 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 Gene3D G3DSA:3.40.50.620 22 210 4.1E-138 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 Gene3D G3DSA:3.40.50.620 355 572 4.1E-138 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 SUPERFAMILY SSF46589 810 874 1.94E-11 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 Pfam PF08264 Anticodon-binding domain of tRNA 616 758 3.1E-38 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 Gene3D G3DSA:1.10.730.10 575 749 2.6E-57 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 810 874 4.8E-12 T 06-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 Gene3D G3DSA:1.10.287.380 803 873 2.8E-8 T 06-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 32 570 8.9E-190 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 PRINTS PR00986 Valyl-tRNA synthetase signature 245 262 1.9E-37 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 PRINTS PR00986 Valyl-tRNA synthetase signature 53 64 1.9E-37 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 PRINTS PR00986 Valyl-tRNA synthetase signature 454 475 1.9E-37 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 PRINTS PR00986 Valyl-tRNA synthetase signature 485 503 1.9E-37 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 PRINTS PR00986 Valyl-tRNA synthetase signature 360 373 1.9E-37 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 60 71 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 TIGRFAM TIGR00422 valS: valine--tRNA ligase 20 855 0.0 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 SUPERFAMILY SSF50677 210 348 7.72E-53 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 Gene3D G3DSA:3.90.740.10 211 348 9.5E-45 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SMD11_RS22350 817c239725d8477130f6084c26c4fcb3 877 Hamap MF_02004 Valine--tRNA ligase [valS]. 19 875 15.075 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SMD11_RS03205 532f41527dd6cc4fcc263302740a6c0d 329 SUPERFAMILY SSF47413 1 56 1.49E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS03205 532f41527dd6cc4fcc263302740a6c0d 329 SMART SM00354 1 68 1.5E-19 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS03205 532f41527dd6cc4fcc263302740a6c0d 329 Pfam PF13377 Periplasmic binding protein-like domain 165 321 3.6E-30 T 06-07-2017 SMD11_RS03205 532f41527dd6cc4fcc263302740a6c0d 329 Gene3D G3DSA:1.10.260.40 1 48 1.8E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS03205 532f41527dd6cc4fcc263302740a6c0d 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 1.4E-12 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS03205 532f41527dd6cc4fcc263302740a6c0d 329 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 06-07-2017 SMD11_RS03205 532f41527dd6cc4fcc263302740a6c0d 329 SUPERFAMILY SSF53822 58 323 1.63E-59 T 06-07-2017 IPR028082 Periplasmic binding protein-like I SMD11_RS03205 532f41527dd6cc4fcc263302740a6c0d 329 Gene3D G3DSA:3.40.50.2300 49 169 1.4E-37 T 06-07-2017 SMD11_RS03205 532f41527dd6cc4fcc263302740a6c0d 329 Gene3D G3DSA:3.40.50.2300 170 302 8.2E-38 T 06-07-2017 SMD11_RS10250 687ad4422586c26d3e030d2d7a4c2f70 369 Pfam PF00005 ABC transporter 45 207 4.0E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS10250 687ad4422586c26d3e030d2d7a4c2f70 369 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 258 351 8.3E-22 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS10250 687ad4422586c26d3e030d2d7a4c2f70 369 Gene3D G3DSA:3.40.50.300 24 280 1.4E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10250 687ad4422586c26d3e030d2d7a4c2f70 369 SMART SM00382 53 257 4.0E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS10250 687ad4422586c26d3e030d2d7a4c2f70 369 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 259 320 2.3E-19 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS10250 687ad4422586c26d3e030d2d7a4c2f70 369 SUPERFAMILY SSF52540 25 278 3.22E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10250 687ad4422586c26d3e030d2d7a4c2f70 369 ProSitePatterns PS00211 ABC transporters family signature. 180 194 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS32180 e9d25a8efd350592921808cceb92b24f 191 SUPERFAMILY SSF50405 121 188 2.78E-5 T 06-07-2017 IPR008999 Actin cross-linking SMD11_RS32180 e9d25a8efd350592921808cceb92b24f 191 Gene3D G3DSA:2.80.10.50 74 141 3.8E-7 T 06-07-2017 SMD11_RS32180 e9d25a8efd350592921808cceb92b24f 191 SUPERFAMILY SSF50405 74 115 9.55E-8 T 06-07-2017 IPR008999 Actin cross-linking SMD11_RS09925 7f31471798b48733516f5067d8ffea8b 907 Pfam PF02884 Polysaccharide lyase family 8, C-terminal beta-sandwich domain 794 854 1.1E-11 T 06-07-2017 IPR004103 Polysaccharide lyase family 8, C-terminal GO:0005576|GO:0016829 SMD11_RS09925 7f31471798b48733516f5067d8ffea8b 907 Gene3D G3DSA:2.60.220.10 792 902 8.4E-28 T 06-07-2017 IPR004103 Polysaccharide lyase family 8, C-terminal GO:0005576|GO:0016829 SMD11_RS09925 7f31471798b48733516f5067d8ffea8b 907 SUPERFAMILY SSF74650 518 789 7.33E-87 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMD11_RS09925 7f31471798b48733516f5067d8ffea8b 907 SUPERFAMILY SSF48230 147 508 8.55E-102 T 06-07-2017 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 SMD11_RS09925 7f31471798b48733516f5067d8ffea8b 907 Gene3D G3DSA:1.50.10.100 147 531 1.9E-105 T 06-07-2017 IPR012329 Polysaccharide lyase family 8, N-terminal GO:0005975|GO:0016837 SMD11_RS09925 7f31471798b48733516f5067d8ffea8b 907 SUPERFAMILY SSF49863 792 902 1.43E-19 T 06-07-2017 IPR011071 Polysaccharide lyase family 8-like, C-terminal GO:0005975 SMD11_RS09925 7f31471798b48733516f5067d8ffea8b 907 Gene3D G3DSA:2.70.98.10 532 788 2.6E-88 T 06-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 SMD11_RS09925 7f31471798b48733516f5067d8ffea8b 907 Pfam PF08124 Polysaccharide lyase family 8, N terminal alpha-helical domain 156 478 7.1E-101 T 06-07-2017 IPR012970 Polysaccharide lyase 8, N-terminal alpha-helical SMD11_RS09925 7f31471798b48733516f5067d8ffea8b 907 Pfam PF02278 Polysaccharide lyase family 8, super-sandwich domain 520 778 3.6E-79 T 06-07-2017 IPR003159 Polysaccharide lyase family 8, central domain GO:0005576|GO:0016829 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 654 32.813 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 SUPERFAMILY SSF52954 549 653 1.34E-27 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 189 235 2.7E-13 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 Gene3D G3DSA:3.40.50.800 551 655 1.0E-29 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 648 9.9E-195 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 Gene3D G3DSA:3.30.54.20 131 203 1.6E-10 T 06-07-2017 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 SMART SM00863 179 235 2.2E-20 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 Gene3D G3DSA:3.30.930.10 258 550 4.3E-103 T 06-07-2017 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 341 549 4.4E-36 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 SUPERFAMILY SSF55681 259 546 8.85E-90 T 06-07-2017 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 Gene3D G3DSA:3.30.980.10 66 129 1.8E-42 T 06-07-2017 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 Gene3D G3DSA:3.30.980.10 204 240 1.8E-42 T 06-07-2017 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 Pfam PF03129 Anticodon binding domain 561 648 3.1E-19 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 PRINTS PR01047 Threonyl-tRNA synthetase signature 527 540 1.5E-51 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 PRINTS PR01047 Threonyl-tRNA synthetase signature 348 376 1.5E-51 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 PRINTS PR01047 Threonyl-tRNA synthetase signature 381 404 1.5E-51 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 PRINTS PR01047 Threonyl-tRNA synthetase signature 484 512 1.5E-51 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 PRINTS PR01047 Threonyl-tRNA synthetase signature 554 566 1.5E-51 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD11_RS27115 35b9164d9039fdb16d97007c83cca03a 658 SUPERFAMILY SSF55186 64 257 2.62E-53 T 06-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 SMD11_RS19560 21cee5b430c12cb4cac36fa6d4fae004 914 SUPERFAMILY SSF56601 576 769 7.8E-38 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS19560 21cee5b430c12cb4cac36fa6d4fae004 914 SUPERFAMILY SSF56601 507 536 7.8E-38 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS19560 21cee5b430c12cb4cac36fa6d4fae004 914 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 579 769 3.0E-30 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SMD11_RS19560 21cee5b430c12cb4cac36fa6d4fae004 914 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 643 660 3.8E-14 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD11_RS19560 21cee5b430c12cb4cac36fa6d4fae004 914 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 586 597 3.8E-14 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD11_RS19560 21cee5b430c12cb4cac36fa6d4fae004 914 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 670 683 3.8E-14 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD11_RS19560 21cee5b430c12cb4cac36fa6d4fae004 914 Gene3D G3DSA:3.40.710.10 576 773 1.3E-50 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS15785 982323c4ac25ae3696143bec8815b569 229 Pfam PF03483 B3/4 domain 66 197 7.7E-17 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SMD11_RS15785 982323c4ac25ae3696143bec8815b569 229 SMART SM00873 65 215 4.3E-8 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SMD11_RS15785 982323c4ac25ae3696143bec8815b569 229 SUPERFAMILY SSF56037 57 211 3.66E-25 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 SMD11_RS15785 982323c4ac25ae3696143bec8815b569 229 Gene3D G3DSA:3.50.40.10 58 197 8.9E-12 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 SMD11_RS22985 a1c44ca1e01c54ac91288142f4a8f907 286 SUPERFAMILY SSF50494 55 267 2.23E-14 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS22985 a1c44ca1e01c54ac91288142f4a8f907 286 Pfam PF00089 Trypsin 67 248 1.6E-4 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD11_RS22985 a1c44ca1e01c54ac91288142f4a8f907 286 Gene3D G3DSA:2.40.10.10 77 166 1.2E-5 T 06-07-2017 SMD11_RS09120 374cd6d922432de92383ca2e953e5227 1316 SUPERFAMILY SSF52540 1076 1247 5.84E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09120 374cd6d922432de92383ca2e953e5227 1316 Gene3D G3DSA:3.40.50.300 1085 1155 2.2E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09120 374cd6d922432de92383ca2e953e5227 1316 Gene3D G3DSA:3.40.50.300 819 1001 2.0E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09120 374cd6d922432de92383ca2e953e5227 1316 Gene3D G3DSA:3.40.50.300 438 658 5.1E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09120 374cd6d922432de92383ca2e953e5227 1316 SUPERFAMILY SSF52540 759 1014 9.45E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09120 374cd6d922432de92383ca2e953e5227 1316 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 739 1310 1.4E-233 T 06-07-2017 IPR023837 EccCb-like, Actinobacteria SMD11_RS09120 374cd6d922432de92383ca2e953e5227 1316 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 688 3.2E-263 T 06-07-2017 IPR023836 EccCa-like, Actinobacteria SMD11_RS09120 374cd6d922432de92383ca2e953e5227 1316 SUPERFAMILY SSF52540 429 655 3.47E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09120 374cd6d922432de92383ca2e953e5227 1316 Pfam PF01580 FtsK/SpoIIIE family 436 563 2.6E-24 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMD11_RS09120 374cd6d922432de92383ca2e953e5227 1316 Pfam PF01580 FtsK/SpoIIIE family 798 1033 1.7E-47 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMD11_RS09120 374cd6d922432de92383ca2e953e5227 1316 SMART SM00382 1106 1265 0.93 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS09120 374cd6d922432de92383ca2e953e5227 1316 SMART SM00382 820 996 1.2 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS09120 374cd6d922432de92383ca2e953e5227 1316 SMART SM00382 465 644 0.44 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS29470 d7053008494679de67dd463e636449b9 247 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 104 210 2.8E-11 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD11_RS29470 d7053008494679de67dd463e636449b9 247 SUPERFAMILY SSF56784 9 243 2.91E-36 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS29470 d7053008494679de67dd463e636449b9 247 Gene3D G3DSA:1.10.150.240 25 113 1.1E-6 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 SMD11_RS29470 d7053008494679de67dd463e636449b9 247 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 209 5.0E-12 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS29470 d7053008494679de67dd463e636449b9 247 Gene3D G3DSA:3.40.50.1000 119 242 8.1E-33 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS29470 d7053008494679de67dd463e636449b9 247 Gene3D G3DSA:3.40.50.1000 7 24 8.1E-33 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS29470 d7053008494679de67dd463e636449b9 247 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 10 216 2.5E-48 T 06-07-2017 IPR010976 Beta-phosphoglucomutase hydrolase SMD11_RS11295 d3e972a02d24de6c5868e6a25ab9ffaf 174 SUPERFAMILY SSF55729 10 156 6.52E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS11295 d3e972a02d24de6c5868e6a25ab9ffaf 174 Gene3D G3DSA:3.40.630.30 7 159 1.4E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS11295 d3e972a02d24de6c5868e6a25ab9ffaf 174 Pfam PF00583 Acetyltransferase (GNAT) family 57 150 7.8E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS25230 32e5b6af4a03ca44285588085c3b6aa8 418 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 12 418 1.4E-185 T 06-07-2017 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SMD11_RS25230 32e5b6af4a03ca44285588085c3b6aa8 418 Pfam PF00266 Aminotransferase class-V 31 406 1.0E-150 T 06-07-2017 IPR000192 Aminotransferase class V domain SMD11_RS25230 32e5b6af4a03ca44285588085c3b6aa8 418 SUPERFAMILY SSF53383 9 413 2.2E-123 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS25230 32e5b6af4a03ca44285588085c3b6aa8 418 Gene3D G3DSA:3.90.1150.10 294 412 3.0E-29 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS25230 32e5b6af4a03ca44285588085c3b6aa8 418 Gene3D G3DSA:3.40.640.10 42 293 2.1E-85 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS03655 7ef7a8ca4394a03781da293626cf7392 962 SUPERFAMILY SSF52540 481 704 2.86E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03655 7ef7a8ca4394a03781da293626cf7392 962 SMART SM00490 819 901 3.6E-23 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS03655 7ef7a8ca4394a03781da293626cf7392 962 SUPERFAMILY SSF52540 711 957 1.49E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03655 7ef7a8ca4394a03781da293626cf7392 962 SMART SM00487 491 676 6.0E-28 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS03655 7ef7a8ca4394a03781da293626cf7392 962 Gene3D G3DSA:3.40.50.300 490 658 2.1E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03655 7ef7a8ca4394a03781da293626cf7392 962 Gene3D G3DSA:3.40.50.300 787 936 2.9E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03655 7ef7a8ca4394a03781da293626cf7392 962 Pfam PF12419 SNF2 Helicase protein 301 444 7.3E-39 T 06-07-2017 IPR022138 Helicase SWF/SNF-related SMD11_RS03655 7ef7a8ca4394a03781da293626cf7392 962 Pfam PF00176 SNF2 family N-terminal domain 514 773 1.0E-48 T 06-07-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 SMD11_RS03655 7ef7a8ca4394a03781da293626cf7392 962 Pfam PF00271 Helicase conserved C-terminal domain 791 901 1.4E-17 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS02015 6aa7e891fddc6f704f5fe4571379f87b 518 Pfam PF00135 Carboxylesterase family 381 498 7.8E-8 T 06-07-2017 IPR002018 Carboxylesterase, type B SMD11_RS02015 6aa7e891fddc6f704f5fe4571379f87b 518 Pfam PF00135 Carboxylesterase family 19 333 5.8E-81 T 06-07-2017 IPR002018 Carboxylesterase, type B SMD11_RS02015 6aa7e891fddc6f704f5fe4571379f87b 518 SUPERFAMILY SSF53474 19 507 3.0E-106 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS02015 6aa7e891fddc6f704f5fe4571379f87b 518 Gene3D G3DSA:3.40.50.1820 13 507 2.9E-121 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS02015 6aa7e891fddc6f704f5fe4571379f87b 518 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 187 202 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site SMD11_RS02015 6aa7e891fddc6f704f5fe4571379f87b 518 PRINTS PR00878 Cholinesterase signature 119 148 3.8E-6 T 06-07-2017 IPR000997 Cholinesterase GO:0004104 Reactome: R-HSA-112311|Reactome: R-HSA-1483191|Reactome: R-HSA-422085 SMD11_RS02015 6aa7e891fddc6f704f5fe4571379f87b 518 PRINTS PR00878 Cholinesterase signature 424 436 3.8E-6 T 06-07-2017 IPR000997 Cholinesterase GO:0004104 Reactome: R-HSA-112311|Reactome: R-HSA-1483191|Reactome: R-HSA-422085 SMD11_RS32450 0562bedf19ca31bd3bf01c5b2ef08abc 779 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 224 336 1.1E-30 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32450 0562bedf19ca31bd3bf01c5b2ef08abc 779 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 638 729 6.8E-5 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32450 0562bedf19ca31bd3bf01c5b2ef08abc 779 SUPERFAMILY SSF53901 578 773 1.27E-18 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32450 0562bedf19ca31bd3bf01c5b2ef08abc 779 SUPERFAMILY SSF53901 193 375 9.26E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32450 0562bedf19ca31bd3bf01c5b2ef08abc 779 SUPERFAMILY SSF53901 391 614 1.86E-32 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32450 0562bedf19ca31bd3bf01c5b2ef08abc 779 Gene3D G3DSA:3.40.47.10 232 375 6.5E-48 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32450 0562bedf19ca31bd3bf01c5b2ef08abc 779 Gene3D G3DSA:3.40.47.10 641 773 7.6E-11 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32450 0562bedf19ca31bd3bf01c5b2ef08abc 779 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 64 214 2.8E-15 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32450 0562bedf19ca31bd3bf01c5b2ef08abc 779 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 435 609 4.1E-19 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32450 0562bedf19ca31bd3bf01c5b2ef08abc 779 SUPERFAMILY SSF53901 6 222 4.57E-30 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32450 0562bedf19ca31bd3bf01c5b2ef08abc 779 SMART SM00825 Beta-ketoacyl synthase 8 378 2.1E-9 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32450 0562bedf19ca31bd3bf01c5b2ef08abc 779 Gene3D G3DSA:3.40.47.10 433 621 3.9E-28 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32450 0562bedf19ca31bd3bf01c5b2ef08abc 779 Gene3D G3DSA:3.40.47.10 8 228 4.1E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS04315 27493eae110a7aca5c69c157eacde811 505 SUPERFAMILY SSF53790 254 486 5.89E-53 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS04315 27493eae110a7aca5c69c157eacde811 505 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 257 464 9.0E-36 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS04315 27493eae110a7aca5c69c157eacde811 505 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 221 4.6E-52 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS04315 27493eae110a7aca5c69c157eacde811 505 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 14 28 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMD11_RS04315 27493eae110a7aca5c69c157eacde811 505 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 9 240 2.5E-69 T 06-07-2017 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 SMD11_RS04315 27493eae110a7aca5c69c157eacde811 505 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 258 502 9.2E-83 T 06-07-2017 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 SMD11_RS04315 27493eae110a7aca5c69c157eacde811 505 SUPERFAMILY SSF53790 6 246 4.71E-50 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS04315 27493eae110a7aca5c69c157eacde811 505 Gene3D G3DSA:3.40.1010.10 8 140 4.3E-38 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS04315 27493eae110a7aca5c69c157eacde811 505 Gene3D G3DSA:3.30.950.10 370 480 1.5E-11 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS04315 27493eae110a7aca5c69c157eacde811 505 Gene3D G3DSA:3.40.1010.10 256 369 2.3E-28 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS34310 d3bb1af6b4ffd52adeb07b9e464175a6 428 Pfam PF00266 Aminotransferase class-V 23 394 6.6E-46 T 06-07-2017 IPR000192 Aminotransferase class V domain SMD11_RS34310 d3bb1af6b4ffd52adeb07b9e464175a6 428 SUPERFAMILY SSF53383 10 398 1.29E-77 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS34310 d3bb1af6b4ffd52adeb07b9e464175a6 428 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 208 228 - T 06-07-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site SMD11_RS34310 d3bb1af6b4ffd52adeb07b9e464175a6 428 Gene3D G3DSA:3.90.1150.10 292 399 5.8E-18 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS34310 d3bb1af6b4ffd52adeb07b9e464175a6 428 Gene3D G3DSA:3.40.640.10 33 291 4.5E-56 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS30095 4db8861c9574349a67dd677aea6e2d83 162 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 40 153 8.2E-24 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 SMD11_RS30095 4db8861c9574349a67dd677aea6e2d83 162 SUPERFAMILY SSF54637 34 161 1.91E-29 T 06-07-2017 IPR029069 HotDog domain SMD11_RS30095 4db8861c9574349a67dd677aea6e2d83 162 Pfam PF03061 Thioesterase superfamily 70 146 4.7E-16 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 SMD11_RS30095 4db8861c9574349a67dd677aea6e2d83 162 Gene3D G3DSA:3.10.129.10 33 159 2.6E-35 T 06-07-2017 IPR029069 HotDog domain SMD11_RS22055 91c8fd24bd5c965b06c535ef80fbdaf8 452 Gene3D G3DSA:3.40.50.410 66 233 9.0E-12 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS22055 91c8fd24bd5c965b06c535ef80fbdaf8 452 SMART SM00327 64 241 4.3E-11 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS22055 91c8fd24bd5c965b06c535ef80fbdaf8 452 Pfam PF13768 von Willebrand factor type A domain 66 225 7.0E-11 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS22055 91c8fd24bd5c965b06c535ef80fbdaf8 452 SUPERFAMILY SSF53300 63 241 6.33E-21 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS05470 fe2d4055efc316ef9b5e7059fb3e250c 242 SMART SM00422 10 79 6.8E-20 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS05470 fe2d4055efc316ef9b5e7059fb3e250c 242 SUPERFAMILY SSF46955 10 85 1.28E-17 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS05470 fe2d4055efc316ef9b5e7059fb3e250c 242 Gene3D G3DSA:1.10.1660.10 11 84 2.8E-19 T 06-07-2017 SMD11_RS05470 fe2d4055efc316ef9b5e7059fb3e250c 242 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 11 22 3.7E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS05470 fe2d4055efc316ef9b5e7059fb3e250c 242 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 22 35 3.7E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS05470 fe2d4055efc316ef9b5e7059fb3e250c 242 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 3.7E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS05470 fe2d4055efc316ef9b5e7059fb3e250c 242 Pfam PF13411 MerR HTH family regulatory protein 11 78 1.5E-18 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS26925 a2576e1614a122b7572680da93778a04 520 Pfam PF07690 Major Facilitator Superfamily 29 420 3.2E-53 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS26925 a2576e1614a122b7572680da93778a04 520 SUPERFAMILY SSF103473 481 508 3.01E-26 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS26925 a2576e1614a122b7572680da93778a04 520 SUPERFAMILY SSF103473 225 430 3.01E-26 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS26925 a2576e1614a122b7572680da93778a04 520 Gene3D G3DSA:1.20.1250.20 18 207 3.3E-31 T 06-07-2017 SMD11_RS26925 a2576e1614a122b7572680da93778a04 520 Gene3D G3DSA:1.20.1250.20 482 509 1.1E-20 T 06-07-2017 SMD11_RS26925 a2576e1614a122b7572680da93778a04 520 Gene3D G3DSA:1.20.1250.20 282 431 1.1E-20 T 06-07-2017 SMD11_RS26925 a2576e1614a122b7572680da93778a04 520 SUPERFAMILY SSF103473 14 206 4.58E-43 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS32380 b4815442cc202777f0ddc8cc790102b5 195 Gene3D G3DSA:2.30.110.10 3 131 8.7E-18 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS32380 b4815442cc202777f0ddc8cc790102b5 195 SUPERFAMILY SSF50475 7 131 1.64E-12 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS32380 b4815442cc202777f0ddc8cc790102b5 195 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 102 1.6E-10 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 Gene3D G3DSA:3.20.20.120 128 422 6.6E-139 T 06-07-2017 IPR029065 Enolase C-terminal domain-like SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 SUPERFAMILY SSF54826 4 138 2.46E-52 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 Hamap MF_00318 Enolase [eno]. 2 409 45.426 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 PRINTS PR00148 Enolase signature 361 378 5.8E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 PRINTS PR00148 Enolase signature 107 123 5.8E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 PRINTS PR00148 Enolase signature 37 51 5.8E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 PRINTS PR00148 Enolase signature 161 174 5.8E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 PRINTS PR00148 Enolase signature 309 320 5.8E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 PRINTS PR00148 Enolase signature 332 346 5.8E-47 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 Gene3D G3DSA:3.30.390.10 4 125 1.6E-52 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 PIRSF PIRSF001400 2 422 1.6E-188 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 Pfam PF03952 Enolase, N-terminal domain 4 134 2.2E-55 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 423 1.3E-205 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 SMART SM01193 4 134 6.8E-87 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 ProSitePatterns PS00164 Enolase signature. 332 345 - T 06-07-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 SUPERFAMILY SSF51604 138 423 3.67E-133 T 06-07-2017 IPR029065 Enolase C-terminal domain-like SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 420 1.1E-134 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS20295 cc61240609ca73f8936f0419079a8aad 428 SMART SM01192 139 423 2.0E-230 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS21435 172ac6fb86b2b395bd18304c9d1f753e 509 Gene3D G3DSA:3.30.9.10 339 369 1.3E-5 T 06-07-2017 SMD11_RS21435 172ac6fb86b2b395bd18304c9d1f753e 509 Gene3D G3DSA:3.30.9.10 182 284 1.3E-5 T 06-07-2017 SMD11_RS21435 172ac6fb86b2b395bd18304c9d1f753e 509 SUPERFAMILY SSF51905 97 191 1.68E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS21435 172ac6fb86b2b395bd18304c9d1f753e 509 SUPERFAMILY SSF51905 287 368 1.68E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS21435 172ac6fb86b2b395bd18304c9d1f753e 509 SUPERFAMILY SSF51905 1 67 1.68E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS21435 172ac6fb86b2b395bd18304c9d1f753e 509 Pfam PF01494 FAD binding domain 3 356 2.0E-66 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS21435 172ac6fb86b2b395bd18304c9d1f753e 509 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 170 185 1.9E-27 T 06-07-2017 SMD11_RS21435 172ac6fb86b2b395bd18304c9d1f753e 509 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 322 1.9E-27 T 06-07-2017 SMD11_RS21435 172ac6fb86b2b395bd18304c9d1f753e 509 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 306 1.9E-27 T 06-07-2017 SMD11_RS21435 172ac6fb86b2b395bd18304c9d1f753e 509 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 324 342 1.9E-27 T 06-07-2017 SMD11_RS21435 172ac6fb86b2b395bd18304c9d1f753e 509 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 342 358 1.9E-27 T 06-07-2017 SMD11_RS21435 172ac6fb86b2b395bd18304c9d1f753e 509 Gene3D G3DSA:3.50.50.60 1 181 5.8E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS21435 172ac6fb86b2b395bd18304c9d1f753e 509 Gene3D G3DSA:3.50.50.60 289 329 5.8E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS23795 8500800c8d6b5db661a70c9d99337d88 292 Pfam PF02548 Ketopantoate hydroxymethyltransferase 29 286 8.8E-109 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SMD11_RS23795 8500800c8d6b5db661a70c9d99337d88 292 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 30 291 43.042 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SMD11_RS23795 8500800c8d6b5db661a70c9d99337d88 292 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 36 292 2.4E-96 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SMD11_RS23795 8500800c8d6b5db661a70c9d99337d88 292 Gene3D G3DSA:3.20.20.60 28 292 7.6E-113 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS23795 8500800c8d6b5db661a70c9d99337d88 292 PIRSF PIRSF000388 23 292 1.4E-110 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 SMD11_RS23795 8500800c8d6b5db661a70c9d99337d88 292 SUPERFAMILY SSF51621 29 291 2.59E-103 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS23880 3441ec424030b9173af1d861c3a7271b 344 SUPERFAMILY SSF47413 3 49 8.94E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS23880 3441ec424030b9173af1d861c3a7271b 344 Gene3D G3DSA:3.40.50.2300 58 170 1.7E-27 T 06-07-2017 SMD11_RS23880 3441ec424030b9173af1d861c3a7271b 344 Gene3D G3DSA:3.40.50.2300 171 334 1.4E-54 T 06-07-2017 SMD11_RS23880 3441ec424030b9173af1d861c3a7271b 344 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 7.2E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS23880 3441ec424030b9173af1d861c3a7271b 344 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 7.2E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS23880 3441ec424030b9173af1d861c3a7271b 344 SMART SM00354 2 69 1.2E-23 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS23880 3441ec424030b9173af1d861c3a7271b 344 SUPERFAMILY SSF53822 59 338 2.75E-68 T 06-07-2017 IPR028082 Periplasmic binding protein-like I SMD11_RS23880 3441ec424030b9173af1d861c3a7271b 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 06-07-2017 SMD11_RS23880 3441ec424030b9173af1d861c3a7271b 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 47 2.5E-14 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS23880 3441ec424030b9173af1d861c3a7271b 344 Gene3D G3DSA:1.10.260.40 3 47 3.9E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS23880 3441ec424030b9173af1d861c3a7271b 344 Pfam PF13377 Periplasmic binding protein-like domain 171 333 3.6E-38 T 06-07-2017 SMD11_RS21000 270a59e579088d8b9bfc8ed4eeb3b483 477 Gene3D G3DSA:3.40.50.720 236 464 4.8E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS21000 270a59e579088d8b9bfc8ed4eeb3b483 477 Gene3D G3DSA:3.40.50.10380 93 235 1.0E-54 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMD11_RS21000 270a59e579088d8b9bfc8ed4eeb3b483 477 SMART SM00919 238 465 1.5E-106 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 SMD11_RS21000 270a59e579088d8b9bfc8ed4eeb3b483 477 SUPERFAMILY SSF51735 238 472 1.87E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS21000 270a59e579088d8b9bfc8ed4eeb3b483 477 Pfam PF00390 Malic enzyme, N-terminal domain 94 226 3.2E-30 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMD11_RS21000 270a59e579088d8b9bfc8ed4eeb3b483 477 SMART SM01274 93 226 1.5E-84 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMD11_RS21000 270a59e579088d8b9bfc8ed4eeb3b483 477 Gene3D G3DSA:3.30.70.260 25 78 4.6E-4 T 06-07-2017 SMD11_RS21000 270a59e579088d8b9bfc8ed4eeb3b483 477 PIRSF PIRSF000106 63 476 2.0E-82 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 SMD11_RS21000 270a59e579088d8b9bfc8ed4eeb3b483 477 SUPERFAMILY SSF53223 87 236 1.15E-56 T 06-07-2017 SMD11_RS21000 270a59e579088d8b9bfc8ed4eeb3b483 477 PRINTS PR00072 Malic enzyme signature 358 374 2.9E-12 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 SMD11_RS21000 270a59e579088d8b9bfc8ed4eeb3b483 477 PRINTS PR00072 Malic enzyme signature 265 281 2.9E-12 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 SMD11_RS21000 270a59e579088d8b9bfc8ed4eeb3b483 477 PRINTS PR00072 Malic enzyme signature 155 177 2.9E-12 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 SMD11_RS21000 270a59e579088d8b9bfc8ed4eeb3b483 477 PRINTS PR00072 Malic enzyme signature 234 250 2.9E-12 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 SMD11_RS21000 270a59e579088d8b9bfc8ed4eeb3b483 477 Pfam PF03949 Malic enzyme, NAD binding domain 240 464 2.4E-22 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 SMD11_RS24375 dcbd4263592f68c39c26704ce0e4bb33 210 Pfam PF00174 Oxidoreductase molybdopterin binding domain 33 181 4.6E-28 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD11_RS24375 dcbd4263592f68c39c26704ce0e4bb33 210 Gene3D G3DSA:3.90.420.10 16 200 3.1E-45 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD11_RS24375 dcbd4263592f68c39c26704ce0e4bb33 210 SUPERFAMILY SSF56524 13 202 2.35E-52 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 SMD11_RS26070 141feeb0c0e1730defa3292826f23404 152 SUPERFAMILY SSF46785 1 59 1.03E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26070 141feeb0c0e1730defa3292826f23404 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 1.3E-15 T 06-07-2017 SMD11_RS26070 141feeb0c0e1730defa3292826f23404 152 SUPERFAMILY SSF54909 63 145 5.36E-12 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS26070 141feeb0c0e1730defa3292826f23404 152 Pfam PF01037 Lrp/AsnC ligand binding domain 69 139 1.0E-11 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS26070 141feeb0c0e1730defa3292826f23404 152 SMART SM00344 1 110 1.5E-34 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD11_RS26070 141feeb0c0e1730defa3292826f23404 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 4.9E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS26070 141feeb0c0e1730defa3292826f23404 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 4.9E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS26070 141feeb0c0e1730defa3292826f23404 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 4.9E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS26070 141feeb0c0e1730defa3292826f23404 152 Gene3D G3DSA:1.10.10.10 1 52 5.9E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26070 141feeb0c0e1730defa3292826f23404 152 Gene3D G3DSA:3.30.70.920 54 145 5.8E-16 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS07225 99a19f5d61ebda5b436db8477f2a0f9b 267 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS07225 99a19f5d61ebda5b436db8477f2a0f9b 267 SMART SM00382 51 225 2.1E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS07225 99a19f5d61ebda5b436db8477f2a0f9b 267 SUPERFAMILY SSF52540 23 242 4.06E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07225 99a19f5d61ebda5b436db8477f2a0f9b 267 Pfam PF00005 ABC transporter 42 175 1.5E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS07225 99a19f5d61ebda5b436db8477f2a0f9b 267 Gene3D G3DSA:3.40.50.300 17 228 8.4E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20175 5a462f420559ea9b74473fe1eb38c9a0 492 Gene3D G3DSA:3.90.550.10 4 261 1.1E-72 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20175 5a462f420559ea9b74473fe1eb38c9a0 492 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 405 440 3.0E-6 T 06-07-2017 IPR001451 Hexapeptide repeat SMD11_RS20175 5a462f420559ea9b74473fe1eb38c9a0 492 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 363 392 0.0029 T 06-07-2017 IPR001451 Hexapeptide repeat SMD11_RS20175 5a462f420559ea9b74473fe1eb38c9a0 492 SUPERFAMILY SSF53448 8 264 1.34E-60 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20175 5a462f420559ea9b74473fe1eb38c9a0 492 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 8 465 1.2E-165 T 06-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 SMD11_RS20175 5a462f420559ea9b74473fe1eb38c9a0 492 SUPERFAMILY SSF51161 260 475 3.26E-44 T 06-07-2017 IPR011004 Trimeric LpxA-like SMD11_RS20175 5a462f420559ea9b74473fe1eb38c9a0 492 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 6 463 40.411 T 06-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 SMD11_RS20175 5a462f420559ea9b74473fe1eb38c9a0 492 Gene3D G3DSA:2.160.10.10 267 449 4.4E-44 T 06-07-2017 SMD11_RS20175 5a462f420559ea9b74473fe1eb38c9a0 492 Pfam PF12804 MobA-like NTP transferase domain 9 142 1.4E-20 T 06-07-2017 IPR025877 MobA-like NTP transferase SMD11_RS24035 c5fa71b2bf6f898fdc062a300baf6457 260 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 73 88 - T 06-07-2017 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 SMD11_RS24035 c5fa71b2bf6f898fdc062a300baf6457 260 Hamap MF_00013 Octanoyltransferase [lipB]. 3 253 31.909 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SMD11_RS24035 c5fa71b2bf6f898fdc062a300baf6457 260 SUPERFAMILY SSF55681 13 132 5.55E-60 T 06-07-2017 SMD11_RS24035 c5fa71b2bf6f898fdc062a300baf6457 260 SUPERFAMILY SSF55681 178 252 5.55E-60 T 06-07-2017 SMD11_RS24035 c5fa71b2bf6f898fdc062a300baf6457 260 PIRSF PIRSF016262 3 257 3.2E-56 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SMD11_RS24035 c5fa71b2bf6f898fdc062a300baf6457 260 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 77 129 6.0E-21 T 06-07-2017 SMD11_RS24035 c5fa71b2bf6f898fdc062a300baf6457 260 Gene3D G3DSA:3.90.1550.10 179 250 1.7E-74 T 06-07-2017 SMD11_RS24035 c5fa71b2bf6f898fdc062a300baf6457 260 Gene3D G3DSA:3.90.1550.10 14 136 1.7E-74 T 06-07-2017 SMD11_RS04005 b96dd36578301488c194d810b9f673ee 290 SUPERFAMILY SSF55785 68 169 7.5E-11 T 06-07-2017 IPR000014 PAS domain SMD11_RS04005 b96dd36578301488c194d810b9f673ee 290 Pfam PF00196 Bacterial regulatory proteins, luxR family 202 251 2.4E-5 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS04005 b96dd36578301488c194d810b9f673ee 290 Pfam PF08448 PAS fold 77 158 2.6E-7 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS04005 b96dd36578301488c194d810b9f673ee 290 Gene3D G3DSA:1.10.10.10 202 257 6.0E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04005 b96dd36578301488c194d810b9f673ee 290 SMART SM00091 71 137 1.4E-4 T 06-07-2017 IPR000014 PAS domain SMD11_RS04005 b96dd36578301488c194d810b9f673ee 290 SUPERFAMILY SSF46894 182 259 3.06E-9 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS04005 b96dd36578301488c194d810b9f673ee 290 SMART SM00421 195 252 9.0E-4 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS04005 b96dd36578301488c194d810b9f673ee 290 Gene3D G3DSA:3.30.450.20 73 169 1.8E-9 T 06-07-2017 SMD11_RS04005 b96dd36578301488c194d810b9f673ee 290 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 72 168 3.2E-6 T 06-07-2017 IPR000014 PAS domain SMD11_RS33995 dffa9565e88cbff36f2e0509cccbd1cb 334 Pfam PF00583 Acetyltransferase (GNAT) family 75 135 2.9E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS33995 dffa9565e88cbff36f2e0509cccbd1cb 334 SUPERFAMILY SSF55729 73 252 1.66E-13 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS33995 dffa9565e88cbff36f2e0509cccbd1cb 334 Gene3D G3DSA:3.40.630.30 208 329 4.7E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS33995 dffa9565e88cbff36f2e0509cccbd1cb 334 SUPERFAMILY SSF55729 212 329 3.04E-10 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS33995 dffa9565e88cbff36f2e0509cccbd1cb 334 Gene3D G3DSA:3.40.630.30 15 133 2.8E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 Gene3D G3DSA:2.40.50.140 653 720 8.3E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 9 725 26.849 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 5 722 0.0 T 06-07-2017 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 SUPERFAMILY SSF54211 6 151 2.33E-45 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 Pfam PF00013 KH domain 583 640 4.2E-11 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 SMART SM00316 649 723 2.6E-17 T 06-07-2017 IPR022967 RNA-binding domain, S1 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 267 343 3.4E-16 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 17 720 3.0E-261 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 Gene3D G3DSA:3.30.1370.10 579 652 7.1E-24 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 Pfam PF01138 3' exoribonuclease family, domain 1 348 480 1.8E-13 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 Pfam PF01138 3' exoribonuclease family, domain 1 20 151 2.3E-17 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 Gene3D G3DSA:1.10.10.400 263 335 1.5E-23 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 SUPERFAMILY SSF55666 474 573 1.96E-24 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 SUPERFAMILY SSF54791 576 688 8.43E-20 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 SUPERFAMILY SSF54211 321 492 1.06E-41 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 PIRSF PIRSF005499 7 738 3.2E-282 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 SMART SM00322 579 643 1.6E-12 T 06-07-2017 IPR004087 K Homology domain GO:0003676 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 SUPERFAMILY SSF55666 152 260 5.18E-29 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 Gene3D G3DSA:3.30.230.70 336 570 2.4E-80 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 Gene3D G3DSA:3.30.230.70 8 249 2.9E-83 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 Pfam PF00575 S1 RNA binding domain 648 718 1.7E-11 T 06-07-2017 IPR003029 S1 domain GO:0003676 SMD11_RS09105 092999d42dff849f96724e6d87e29b78 738 SUPERFAMILY SSF46915 264 344 8.37E-17 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SMD11_RS32630 886b24f7c901906a67342e43c5355778 356 TIGRFAM TIGR00433 bioB: biotin synthase 33 323 8.3E-111 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMD11_RS32630 886b24f7c901906a67342e43c5355778 356 Pfam PF04055 Radical SAM superfamily 68 223 1.0E-12 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS32630 886b24f7c901906a67342e43c5355778 356 SMART SM00729 58 264 1.1E-38 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD11_RS32630 886b24f7c901906a67342e43c5355778 356 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 235 323 1.1E-12 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMD11_RS32630 886b24f7c901906a67342e43c5355778 356 SMART SM00876 235 325 1.1E-29 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMD11_RS32630 886b24f7c901906a67342e43c5355778 356 Hamap MF_01694 Biotin synthase [bioB]. 18 326 39.274 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMD11_RS32630 886b24f7c901906a67342e43c5355778 356 PIRSF PIRSF001619 6 332 7.8E-103 T 06-07-2017 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMD11_RS32630 886b24f7c901906a67342e43c5355778 356 Gene3D G3DSA:3.20.20.70 20 325 2.3E-84 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS32630 886b24f7c901906a67342e43c5355778 356 SUPERFAMILY SSF102114 21 324 1.03E-74 T 06-07-2017 SMD11_RS11970 cc37d70d1ee3d6e463b7c15646a19166 325 Gene3D G3DSA:1.10.3720.10 97 316 8.8E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11970 cc37d70d1ee3d6e463b7c15646a19166 325 SUPERFAMILY SSF161098 99 306 2.03E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11970 cc37d70d1ee3d6e463b7c15646a19166 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 323 9.8E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS28400 5c59d42d217f944526b8491f611b7838 332 Pfam PF03308 ArgK protein 23 292 1.3E-111 T 06-07-2017 SMD11_RS28400 5c59d42d217f944526b8491f611b7838 332 Gene3D G3DSA:1.20.5.170 3 55 1.7E-22 T 06-07-2017 SMD11_RS28400 5c59d42d217f944526b8491f611b7838 332 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 17 321 2.7E-112 T 06-07-2017 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS28400 5c59d42d217f944526b8491f611b7838 332 Gene3D G3DSA:3.40.50.300 56 258 1.9E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28400 5c59d42d217f944526b8491f611b7838 332 SUPERFAMILY SSF52540 5 326 7.38E-94 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24355 566a10ae94bed354dfe9971eb5391601 643 PRINTS PR00096 Glutamine amidotransferase superfamily signature 531 542 3.2E-10 T 06-07-2017 SMD11_RS24355 566a10ae94bed354dfe9971eb5391601 643 PRINTS PR00096 Glutamine amidotransferase superfamily signature 617 630 3.2E-10 T 06-07-2017 SMD11_RS24355 566a10ae94bed354dfe9971eb5391601 643 PRINTS PR00096 Glutamine amidotransferase superfamily signature 497 506 3.2E-10 T 06-07-2017 SMD11_RS24355 566a10ae94bed354dfe9971eb5391601 643 SUPERFAMILY SSF52317 452 637 6.98E-21 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS24355 566a10ae94bed354dfe9971eb5391601 643 Gene3D G3DSA:3.40.50.880 452 639 7.7E-29 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS24355 566a10ae94bed354dfe9971eb5391601 643 Pfam PF00117 Glutamine amidotransferase class-I 454 636 2.2E-26 T 06-07-2017 IPR017926 Glutamine amidotransferase SMD11_RS24355 566a10ae94bed354dfe9971eb5391601 643 Pfam PF00425 chorismate binding enzyme 126 390 1.6E-42 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal SMD11_RS24355 566a10ae94bed354dfe9971eb5391601 643 PRINTS PR00097 Anthranilate synthase component II signature 531 542 4.1E-9 T 06-07-2017 SMD11_RS24355 566a10ae94bed354dfe9971eb5391601 643 PRINTS PR00097 Anthranilate synthase component II signature 617 630 4.1E-9 T 06-07-2017 SMD11_RS24355 566a10ae94bed354dfe9971eb5391601 643 PRINTS PR00097 Anthranilate synthase component II signature 452 466 4.1E-9 T 06-07-2017 SMD11_RS24355 566a10ae94bed354dfe9971eb5391601 643 SUPERFAMILY SSF56322 61 400 3.27E-61 T 06-07-2017 IPR005801 ADC synthase GO:0009058 SMD11_RS24355 566a10ae94bed354dfe9971eb5391601 643 Gene3D G3DSA:3.60.120.10 108 400 4.3E-55 T 06-07-2017 IPR005801 ADC synthase GO:0009058 SMD11_RS26945 1e51a29f91d3c95ca25a50507bc4ff4b 176 SUPERFAMILY SSF88659 92 163 1.8E-6 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF51735 1195 1323 1.83E-7 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF50129 3117 3238 2.2E-29 T 06-07-2017 IPR011032 GroES-like SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF08990 Erythronolide synthase docking 4 29 2.4E-11 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF00698 Acyl transferase domain 576 908 5.1E-91 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF00698 Acyl transferase domain 2197 2502 2.2E-83 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:3.40.47.10 1654 1915 4.7E-90 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF51735 1402 1517 1.38E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 294 410 5.9E-44 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1911 2027 3.0E-45 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:3.40.47.10 33 298 7.4E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF52151 770 863 3.4E-70 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF52151 573 702 3.4E-70 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 3121 3178 2.3E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SMART SM00823 Phosphopantetheine attachment site 1561 1633 6.3E-30 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SMART SM00823 Phosphopantetheine attachment site 3708 3780 8.8E-34 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2199 2497 7.8E-108 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 577 890 4.3E-118 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:3.40.366.10 769 902 3.1E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:3.40.366.10 565 697 3.1E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF51735 2844 2892 5.51E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF51735 2922 3073 5.51E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SMART SM00829 3102 3407 1.7E-175 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:1.10.1200.10 1559 1633 2.8E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:1.10.1200.10 3704 3780 1.3E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF51735 3201 3378 4.42E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF55048 2322 2384 2.35E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:3.40.47.10 299 465 1.2E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:3.40.47.10 1916 2081 1.1E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF00550 Phosphopantetheine attachment site 1563 1629 1.8E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF00550 Phosphopantetheine attachment site 3710 3776 5.0E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 3229 3250 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF51735 979 1185 9.84E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF13602 Zinc-binding dehydrogenase 3284 3407 1.0E-12 T 06-07-2017 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 199 215 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:3.40.366.10 2193 2318 5.8E-71 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:3.40.366.10 2387 2498 5.8E-71 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF55048 701 769 5.89E-12 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:3.90.180.10 3115 3177 8.7E-11 T 06-07-2017 IPR011032 GroES-like SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF101173 4 35 1.57E-5 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1588 1603 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF08659 KR domain 1401 1454 4.0E-14 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF08659 KR domain 3417 3596 3.7E-55 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF08659 KR domain 1197 1311 7.5E-8 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF53901 33 407 8.0E-106 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1652 1903 1.3E-87 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 286 1.1E-92 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF47336 1558 1667 3.27E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SMART SM01294 3709 3776 6.3E-6 T 06-07-2017 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SMART SM01294 1562 1629 3.1E-5 T 06-07-2017 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1197 1456 7.1E-11 T 06-07-2017 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3417 3597 5.3E-52 T 06-07-2017 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SMART SM00826 2563 2724 3.6E-69 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SMART SM00825 Beta-ketoacyl synthase 1654 2081 8.8E-214 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SMART SM00825 Beta-ketoacyl synthase 38 464 3.3E-223 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3735 3750 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF53901 1647 2024 2.04E-102 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:3.40.50.720 3192 3380 3.0E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF52151 2196 2324 9.42E-67 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF52151 2389 2486 9.42E-67 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1816 1832 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:3.40.50.720 3417 3600 4.5E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:3.40.50.720 1392 1501 3.1E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:3.40.50.720 1196 1306 3.1E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF51735 3417 3673 1.5E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2030 2161 2.2E-11 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 413 536 4.4E-12 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 SUPERFAMILY SSF47336 3700 3790 1.83E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Pfam PF14765 Polyketide synthase dehydratase 2563 2836 3.2E-54 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:3.30.70.250 701 768 1.6E-7 T 06-07-2017 SMD11_RS08045 81672362f1e2224978f5202025423bdb 3887 Gene3D G3DSA:3.30.70.250 2321 2383 3.4E-5 T 06-07-2017 SMD11_RS00735 4edb0f52df595a8493b77b8269b50b06 131 Gene3D G3DSA:1.10.10.10 21 115 4.7E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00735 4edb0f52df595a8493b77b8269b50b06 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 71 2.4E-24 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS00735 4edb0f52df595a8493b77b8269b50b06 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 88 103 2.4E-24 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS00735 4edb0f52df595a8493b77b8269b50b06 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 2.4E-24 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS00735 4edb0f52df595a8493b77b8269b50b06 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 73 88 2.4E-24 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS00735 4edb0f52df595a8493b77b8269b50b06 131 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 62 80 - T 06-07-2017 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 SMD11_RS00735 4edb0f52df595a8493b77b8269b50b06 131 Pfam PF01022 Bacterial regulatory protein, arsR family 43 91 7.9E-17 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS00735 4edb0f52df595a8493b77b8269b50b06 131 SMART SM00418 36 116 8.4E-33 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS00735 4edb0f52df595a8493b77b8269b50b06 131 SUPERFAMILY SSF46785 23 116 3.57E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF50129 3085 3204 2.99E-26 T 06-07-2017 IPR011032 GroES-like SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 3090 3146 4.7E-5 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1730 1981 1.1E-93 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3764 4015 2.8E-90 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 288 5.8E-91 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF00698 Acyl transferase domain 2240 2543 5.0E-53 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF00698 Acyl transferase domain 547 846 2.7E-53 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF00698 Acyl transferase domain 4274 4576 7.4E-54 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM01294 1638 1705 1.6E-7 T 06-07-2017 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM01294 3672 3739 1.3E-4 T 06-07-2017 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3387 3567 5.3E-63 T 06-07-2017 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1358 1534 3.3E-62 T 06-07-2017 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM00825 Beta-ketoacyl synthase 38 466 5.0E-221 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM00825 Beta-ketoacyl synthase 3766 4193 3.9E-220 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM00825 Beta-ketoacyl synthase 1732 2159 1.8E-229 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.40.50.720 3386 3585 8.5E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.40.50.720 1357 1538 6.4E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF53901 32 410 3.01E-106 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 547 827 2.7E-120 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4274 4558 7.7E-121 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2240 2524 1.8E-121 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF53901 1726 2104 2.47E-102 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4143 4257 1.5E-15 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 416 530 4.7E-14 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2109 2223 3.7E-15 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF08659 KR domain 3387 3565 1.1E-59 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF08659 KR domain 1358 1533 1.1E-55 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF52151 4271 4385 1.83E-73 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF52151 4442 4549 1.83E-73 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF51735 1179 1344 2.36E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF55048 4390 4449 7.98E-9 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF47336 1631 1745 1.96E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF51735 3381 3593 4.06E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF52151 713 815 9.68E-75 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF52151 544 658 9.68E-75 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF47336 4798 4875 1.22E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 3199 3220 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.40.50.720 3204 3300 7.1E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF14765 Polyketide synthase dehydratase 894 1173 1.6E-56 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF14765 Polyketide synthase dehydratase 2591 2868 2.1E-53 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF53901 3761 4137 1.18E-101 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM00829 3071 3377 1.2E-179 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM00823 Phosphopantetheine attachment site 4803 4875 2.1E-24 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM00823 Phosphopantetheine attachment site 3671 3743 4.5E-31 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM00823 Phosphopantetheine attachment site 1637 1709 2.8E-32 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM00826 894 1057 5.2E-88 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SMART SM00826 2591 2755 8.4E-86 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.90.180.10 3086 3203 3.4E-44 T 06-07-2017 IPR011032 GroES-like SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF51735 3171 3347 5.8E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF51735 1356 1564 1.04E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF101173 5 36 9.55E-5 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.40.47.10 4028 4194 7.3E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.40.47.10 1994 2159 1.4E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.40.47.10 301 466 2.3E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.40.366.10 2412 2526 1.7E-76 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.40.366.10 4268 4385 5.5E-78 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.40.366.10 4448 4562 5.5E-78 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.40.366.10 542 658 5.4E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.40.366.10 719 829 5.4E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.40.366.10 2235 2351 1.7E-76 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF08990 Erythronolide synthase docking 4 28 7.3E-9 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF55048 2356 2412 1.96E-9 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF47336 3665 3778 2.09E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 201 217 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF55048 663 719 1.14E-8 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF00550 Phosphopantetheine attachment site 4810 4871 3.7E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF00550 Phosphopantetheine attachment site 3673 3739 7.7E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF00550 Phosphopantetheine attachment site 1639 1705 1.1E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF52151 2406 2509 2.46E-72 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF52151 2237 2351 2.46E-72 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:1.10.1200.10 4806 4876 3.3E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:1.10.1200.10 3668 3745 3.2E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:1.10.1200.10 1634 1711 1.8E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1894 1910 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 SUPERFAMILY SSF51735 2874 3048 9.45E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.30.70.250 2355 2406 1.7E-6 T 06-07-2017 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.30.70.250 4389 4442 5.8E-7 T 06-07-2017 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.30.70.250 662 713 4.9E-6 T 06-07-2017 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3698 3713 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 296 413 1.3E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1990 2106 1.4E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4024 4140 5.9E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Pfam PF13602 Zinc-binding dehydrogenase 3257 3377 3.4E-18 T 06-07-2017 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3928 3944 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.40.47.10 32 300 8.1E-96 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.40.47.10 1726 1993 7.2E-93 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08255 8a7d6aebed2f6ed13581c1c12fef146b 4884 Gene3D G3DSA:3.40.47.10 3761 4027 1.3E-89 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS17805 6560e246caf690483c4bf5e7e309421c 234 Pfam PF07729 FCD domain 112 220 2.9E-12 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS17805 6560e246caf690483c4bf5e7e309421c 234 Gene3D G3DSA:1.20.120.530 119 229 7.3E-16 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS17805 6560e246caf690483c4bf5e7e309421c 234 SUPERFAMILY SSF48008 116 229 3.14E-15 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS17805 6560e246caf690483c4bf5e7e309421c 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 70 1.1E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS17805 6560e246caf690483c4bf5e7e309421c 234 SUPERFAMILY SSF46785 7 78 4.28E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17805 6560e246caf690483c4bf5e7e309421c 234 SMART SM00345 16 74 4.8E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS17805 6560e246caf690483c4bf5e7e309421c 234 Gene3D G3DSA:1.10.10.10 4 75 6.6E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33055 f6f5bdb19b0e25b908828fa7439d0b61 220 SMART SM00448 2 115 5.1E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS33055 f6f5bdb19b0e25b908828fa7439d0b61 220 SMART SM00421 151 208 2.4E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS33055 f6f5bdb19b0e25b908828fa7439d0b61 220 Gene3D G3DSA:1.10.10.10 123 214 3.5E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33055 f6f5bdb19b0e25b908828fa7439d0b61 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 6.5E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS33055 f6f5bdb19b0e25b908828fa7439d0b61 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 6.5E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS33055 f6f5bdb19b0e25b908828fa7439d0b61 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 6.5E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS33055 f6f5bdb19b0e25b908828fa7439d0b61 220 Pfam PF00072 Response regulator receiver domain 4 115 1.6E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS33055 f6f5bdb19b0e25b908828fa7439d0b61 220 Gene3D G3DSA:3.40.50.2300 1 122 4.1E-36 T 06-07-2017 SMD11_RS33055 f6f5bdb19b0e25b908828fa7439d0b61 220 SUPERFAMILY SSF46894 141 214 1.02E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS33055 f6f5bdb19b0e25b908828fa7439d0b61 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS33055 f6f5bdb19b0e25b908828fa7439d0b61 220 SUPERFAMILY SSF52172 1 133 1.71E-33 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS33055 f6f5bdb19b0e25b908828fa7439d0b61 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 1.8E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS29050 337b594e46208cf3e580535c5def369d 674 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 285 674 2.0E-90 T 06-07-2017 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component SMD11_RS29050 337b594e46208cf3e580535c5def369d 674 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 136 249 2.7E-17 T 06-07-2017 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain SMD11_RS29050 337b594e46208cf3e580535c5def369d 674 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 36 125 7.0E-10 T 06-07-2017 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain SMD11_RS29050 337b594e46208cf3e580535c5def369d 674 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 285 629 4.5E-85 T 06-07-2017 IPR003776 YcaO-like domain SMD11_RS15020 d8888e1a8cfeafa9458a8f95c2e8a618 287 Gene3D G3DSA:1.10.260.40 15 70 1.9E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS15020 d8888e1a8cfeafa9458a8f95c2e8a618 287 SMART SM00530 19 74 4.5E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS15020 d8888e1a8cfeafa9458a8f95c2e8a618 287 Pfam PF13560 Helix-turn-helix domain 16 78 1.5E-13 T 06-07-2017 SMD11_RS15020 d8888e1a8cfeafa9458a8f95c2e8a618 287 SUPERFAMILY SSF47413 13 71 5.91E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 Gene3D G3DSA:1.25.40.10 562 698 1.5E-22 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 Gene3D G3DSA:1.25.40.10 425 521 1.5E-22 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 Gene3D G3DSA:3.40.50.300 9 177 6.3E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 PRINTS PR00364 Disease resistance protein signature 222 236 1.8E-5 T 06-07-2017 SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 PRINTS PR00364 Disease resistance protein signature 116 130 1.8E-5 T 06-07-2017 SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 PRINTS PR00364 Disease resistance protein signature 31 46 1.8E-5 T 06-07-2017 SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 SUPERFAMILY SSF48452 597 711 2.49E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 SUPERFAMILY SSF48452 435 622 5.6E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 Pfam PF13424 Tetratricopeptide repeat 439 505 3.7E-7 T 06-07-2017 SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 Pfam PF13374 Tetratricopeptide repeat 563 589 0.009 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 Pfam PF13374 Tetratricopeptide repeat 638 667 0.012 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 SUPERFAMILY SSF52540 9 242 1.39E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 SMART SM00382 28 187 5.3E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 SMART SM00028 636 669 14.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 SMART SM00028 556 589 230.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS00395 c025eaaff1485814eaef80138e4711d2 731 SMART SM00028 476 509 0.092 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS13870 5db7592e974a8fcc9288f1bb42f44861 232 Gene3D G3DSA:3.20.20.380 4 214 2.0E-49 T 06-07-2017 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 SMD11_RS13870 5db7592e974a8fcc9288f1bb42f44861 232 SUPERFAMILY SSF110395 5 215 5.75E-44 T 06-07-2017 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 SMD11_RS13870 5db7592e974a8fcc9288f1bb42f44861 232 Pfam PF03932 CutC family 5 205 1.6E-23 T 06-07-2017 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 SMD11_RS12340 d0aa4db8926c2715e928ec21e0b77206 552 Gene3D G3DSA:3.40.50.2300 3 128 1.7E-8 T 06-07-2017 SMD11_RS12340 d0aa4db8926c2715e928ec21e0b77206 552 SUPERFAMILY SSF52172 3 130 1.99E-9 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS12340 d0aa4db8926c2715e928ec21e0b77206 552 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 154 334 2.3E-22 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain SMD11_RS12340 d0aa4db8926c2715e928ec21e0b77206 552 Gene3D G3DSA:3.40.50.300 153 387 5.8E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12340 d0aa4db8926c2715e928ec21e0b77206 552 SUPERFAMILY SSF52540 154 387 2.22E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12340 d0aa4db8926c2715e928ec21e0b77206 552 Pfam PF07811 TadE-like protein 444 486 2.3E-6 T 06-07-2017 IPR012495 TadE-like SMD11_RS11160 91242fd63895f796831827c44de84143 121 Gene3D G3DSA:1.10.10.10 8 95 7.5E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11160 91242fd63895f796831827c44de84143 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 3.8E-9 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS11160 91242fd63895f796831827c44de84143 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 3.8E-9 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS11160 91242fd63895f796831827c44de84143 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 20 35 3.8E-9 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS11160 91242fd63895f796831827c44de84143 121 SUPERFAMILY SSF46785 9 95 1.89E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11160 91242fd63895f796831827c44de84143 121 SMART SM00418 18 96 2.2E-16 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS11160 91242fd63895f796831827c44de84143 121 Pfam PF01022 Bacterial regulatory protein, arsR family 26 71 1.4E-9 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS16895 6d694c45c2f3e221a1c4f388ddacd9b5 144 Pfam PF00825 Ribonuclease P 2 117 4.7E-28 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SMD11_RS16895 6d694c45c2f3e221a1c4f388ddacd9b5 144 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 6 116 1.6E-17 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SMD11_RS16895 6d694c45c2f3e221a1c4f388ddacd9b5 144 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 60 74 - T 06-07-2017 IPR020539 Ribonuclease P, conserved site GO:0004526 SMD11_RS16895 6d694c45c2f3e221a1c4f388ddacd9b5 144 Gene3D G3DSA:3.30.230.10 2 117 1.1E-32 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS16895 6d694c45c2f3e221a1c4f388ddacd9b5 144 SUPERFAMILY SSF54211 2 118 9.86E-25 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS16895 6d694c45c2f3e221a1c4f388ddacd9b5 144 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 2 120 16.788 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SMD11_RS19025 14bf728099e694e8407cd157a52dbaf6 340 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 5.2E-24 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS19025 14bf728099e694e8407cd157a52dbaf6 340 Gene3D G3DSA:1.10.150.20 245 319 9.2E-32 T 06-07-2017 SMD11_RS19025 14bf728099e694e8407cd157a52dbaf6 340 SUPERFAMILY SSF55257 14 48 2.35E-24 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS19025 14bf728099e694e8407cd157a52dbaf6 340 SUPERFAMILY SSF55257 170 220 2.35E-24 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS19025 14bf728099e694e8407cd157a52dbaf6 340 Gene3D G3DSA:2.170.120.12 62 168 1.7E-45 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS19025 14bf728099e694e8407cd157a52dbaf6 340 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 34.252 T 06-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS19025 14bf728099e694e8407cd157a52dbaf6 340 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 257 311 2.0E-24 T 06-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS19025 14bf728099e694e8407cd157a52dbaf6 340 Gene3D G3DSA:3.30.1360.10 7 61 5.7E-11 T 06-07-2017 SMD11_RS19025 14bf728099e694e8407cd157a52dbaf6 340 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 245 302 5.9E-26 T 06-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS19025 14bf728099e694e8407cd157a52dbaf6 340 SUPERFAMILY SSF47789 247 318 1.83E-23 T 06-07-2017 SMD11_RS19025 14bf728099e694e8407cd157a52dbaf6 340 SMART SM00662 18 225 3.6E-94 T 06-07-2017 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS19025 14bf728099e694e8407cd157a52dbaf6 340 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 2.2E-115 T 06-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS19025 14bf728099e694e8407cd157a52dbaf6 340 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 2.4E-19 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS19025 14bf728099e694e8407cd157a52dbaf6 340 SUPERFAMILY SSF56553 48 169 7.85E-42 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS19260 6c39f9d1558ebded42088fe41a3f91ed 500 SUPERFAMILY SSF54631 92 211 9.98E-30 T 06-07-2017 SMD11_RS19260 6c39f9d1558ebded42088fe41a3f91ed 500 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 301 313 - T 06-07-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 SMD11_RS19260 6c39f9d1558ebded42088fe41a3f91ed 500 Pfam PF00571 CBS domain 157 212 4.1E-6 T 06-07-2017 IPR000644 CBS domain SMD11_RS19260 6c39f9d1558ebded42088fe41a3f91ed 500 Pfam PF00571 CBS domain 101 151 2.2E-8 T 06-07-2017 IPR000644 CBS domain SMD11_RS19260 6c39f9d1558ebded42088fe41a3f91ed 500 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 16 499 84.475 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SMD11_RS19260 6c39f9d1558ebded42088fe41a3f91ed 500 SMART SM01240 15 486 0.0 T 06-07-2017 SMD11_RS19260 6c39f9d1558ebded42088fe41a3f91ed 500 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 16 467 1.6E-183 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SMD11_RS19260 6c39f9d1558ebded42088fe41a3f91ed 500 SUPERFAMILY SSF51412 10 98 2.62E-119 T 06-07-2017 SMD11_RS19260 6c39f9d1558ebded42088fe41a3f91ed 500 SUPERFAMILY SSF51412 224 490 2.62E-119 T 06-07-2017 SMD11_RS19260 6c39f9d1558ebded42088fe41a3f91ed 500 SMART SM00116 104 152 1.8E-9 T 06-07-2017 IPR000644 CBS domain SMD11_RS19260 6c39f9d1558ebded42088fe41a3f91ed 500 SMART SM00116 165 213 4.3E-8 T 06-07-2017 IPR000644 CBS domain SMD11_RS19260 6c39f9d1558ebded42088fe41a3f91ed 500 PIRSF PIRSF000130 7 500 5.5E-201 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SMD11_RS19260 6c39f9d1558ebded42088fe41a3f91ed 500 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 16 486 3.6E-157 T 06-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 SMD11_RS19260 6c39f9d1558ebded42088fe41a3f91ed 500 Gene3D G3DSA:3.20.20.70 10 498 5.2E-195 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS19775 8ce4d34d6fdd8082bad530ef9c9caba1 157 SUPERFAMILY SSF46785 7 79 3.26E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19775 8ce4d34d6fdd8082bad530ef9c9caba1 157 Gene3D G3DSA:1.10.10.10 4 78 2.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19775 8ce4d34d6fdd8082bad530ef9c9caba1 157 SMART SM00345 18 77 3.2E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS19775 8ce4d34d6fdd8082bad530ef9c9caba1 157 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 5.8E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 SMART SM00823 Phosphopantetheine attachment site 1334 1406 6.6E-29 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 SUPERFAMILY SSF51735 820 1010 6.0E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 Gene3D G3DSA:3.40.50.720 1031 1215 2.0E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1361 1376 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 SUPERFAMILY SSF52151 174 268 7.32E-64 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 SUPERFAMILY SSF52151 1 114 7.32E-64 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 SUPERFAMILY SSF55048 113 173 2.75E-9 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 SUPERFAMILY SSF51735 1029 1266 3.58E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 SMART SM00826 354 534 6.9E-49 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 SUPERFAMILY SSF47336 1327 1418 1.02E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1 283 7.9E-100 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 Gene3D G3DSA:3.30.70.250 127 172 3.6E-6 T 06-07-2017 SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 Pfam PF00550 Phosphopantetheine attachment site 1336 1402 2.7E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1032 1213 5.3E-51 T 06-07-2017 SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 Pfam PF00698 Acyl transferase domain 1 301 1.6E-53 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 Pfam PF14765 Polyketide synthase dehydratase 354 654 8.6E-45 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 Gene3D G3DSA:3.40.366.10 173 287 3.3E-70 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 Gene3D G3DSA:3.40.366.10 1 108 3.3E-70 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 Pfam PF08659 KR domain 1032 1211 5.1E-52 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 Gene3D G3DSA:1.10.1200.10 1333 1406 6.4E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08050 c26b0622e154c427dbb44497ccd441bc 1507 SMART SM01294 1335 1402 0.0069 T 06-07-2017 SMD11_RS16640 26d55d7023062c4d976b110fbafa7aab 105 Pfam PF07883 Cupin domain 33 100 2.8E-15 T 06-07-2017 IPR013096 Cupin 2, conserved barrel SMD11_RS16640 26d55d7023062c4d976b110fbafa7aab 105 Gene3D G3DSA:2.60.120.10 2 104 4.1E-24 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS16640 26d55d7023062c4d976b110fbafa7aab 105 SUPERFAMILY SSF51182 15 103 4.46E-22 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS27400 5b514714d5346ed2296c97cd71c4e41e 402 SUPERFAMILY SSF55973 3 109 2.47E-43 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD11_RS27400 5b514714d5346ed2296c97cd71c4e41e 402 SUPERFAMILY SSF55973 120 248 9.42E-46 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD11_RS27400 5b514714d5346ed2296c97cd71c4e41e 402 Gene3D G3DSA:3.30.300.10 11 144 1.2E-43 T 06-07-2017 SMD11_RS27400 5b514714d5346ed2296c97cd71c4e41e 402 SUPERFAMILY SSF55973 250 401 3.53E-68 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD11_RS27400 5b514714d5346ed2296c97cd71c4e41e 402 Gene3D G3DSA:3.30.300.10 261 400 3.4E-70 T 06-07-2017 SMD11_RS27400 5b514714d5346ed2296c97cd71c4e41e 402 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 399 8.6E-170 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD11_RS27400 5b514714d5346ed2296c97cd71c4e41e 402 Pfam PF02772 S-adenosylmethionine synthetase, central domain 124 248 6.1E-45 T 06-07-2017 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD11_RS27400 5b514714d5346ed2296c97cd71c4e41e 402 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 400 56.709 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD11_RS27400 5b514714d5346ed2296c97cd71c4e41e 402 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 250 389 3.1E-68 T 06-07-2017 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD11_RS27400 5b514714d5346ed2296c97cd71c4e41e 402 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 126 136 - T 06-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD11_RS27400 5b514714d5346ed2296c97cd71c4e41e 402 PIRSF PIRSF000497 1 401 8.0E-164 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD11_RS27400 5b514714d5346ed2296c97cd71c4e41e 402 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 276 284 - T 06-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD11_RS27400 5b514714d5346ed2296c97cd71c4e41e 402 Gene3D G3DSA:3.30.300.10 145 250 9.7E-39 T 06-07-2017 SMD11_RS27400 5b514714d5346ed2296c97cd71c4e41e 402 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 3.3E-39 T 06-07-2017 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SMD11_RS27495 4e4d009ec56301f2b37a9f2f5cd1b011 364 PIRSF PIRSF006769 1 357 2.2E-115 T 06-07-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 SMD11_RS27495 4e4d009ec56301f2b37a9f2f5cd1b011 364 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 143 353 6.6E-56 T 06-07-2017 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 SMD11_RS27495 4e4d009ec56301f2b37a9f2f5cd1b011 364 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 1 349 3.6E-103 T 06-07-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 SMD11_RS27495 4e4d009ec56301f2b37a9f2f5cd1b011 364 Gene3D G3DSA:3.40.430.10 127 352 5.8E-70 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD11_RS27495 4e4d009ec56301f2b37a9f2f5cd1b011 364 Gene3D G3DSA:3.40.140.10 1 126 2.8E-29 T 06-07-2017 SMD11_RS27495 4e4d009ec56301f2b37a9f2f5cd1b011 364 Pfam PF01872 RibD C-terminal domain 144 348 2.3E-50 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD11_RS27495 4e4d009ec56301f2b37a9f2f5cd1b011 364 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 45 86 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SMD11_RS27495 4e4d009ec56301f2b37a9f2f5cd1b011 364 SUPERFAMILY SSF53927 1 136 1.19E-40 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 SMD11_RS27495 4e4d009ec56301f2b37a9f2f5cd1b011 364 SUPERFAMILY SSF53597 142 351 2.94E-54 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD11_RS27495 4e4d009ec56301f2b37a9f2f5cd1b011 364 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 97 2.4E-18 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 SMD11_RS29605 e71212f7c166c44fa3a81fc42a0dd0f0 193 SUPERFAMILY SSF160631 12 142 1.7E-9 T 06-07-2017 SMD11_RS27350 f02ab80f31c570d16e7d8dd2d26aa87a 428 SUPERFAMILY SSF51556 51 366 1.53E-102 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS27350 f02ab80f31c570d16e7d8dd2d26aa87a 428 Gene3D G3DSA:3.20.20.140 65 407 2.8E-106 T 06-07-2017 SMD11_RS27350 f02ab80f31c570d16e7d8dd2d26aa87a 428 SUPERFAMILY SSF51338 367 427 2.49E-23 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS27350 f02ab80f31c570d16e7d8dd2d26aa87a 428 SUPERFAMILY SSF51338 1 50 2.49E-23 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS27350 f02ab80f31c570d16e7d8dd2d26aa87a 428 Gene3D G3DSA:2.30.40.10 3 64 2.4E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS27350 f02ab80f31c570d16e7d8dd2d26aa87a 428 Pfam PF01979 Amidohydrolase family 47 419 3.9E-20 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 SMD11_RS27350 f02ab80f31c570d16e7d8dd2d26aa87a 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 17 424 3.6E-130 T 06-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 SMD11_RS27350 f02ab80f31c570d16e7d8dd2d26aa87a 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 301 312 - T 06-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 SMD11_RS27350 f02ab80f31c570d16e7d8dd2d26aa87a 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 425 43.534 T 06-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 SMD11_RS30640 29a6b67a6fd62abd7d7e773fdb55742a 293 SUPERFAMILY SSF51735 8 290 1.54E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30640 29a6b67a6fd62abd7d7e773fdb55742a 293 Pfam PF13460 NAD(P)H-binding 13 147 2.4E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30640 29a6b67a6fd62abd7d7e773fdb55742a 293 Gene3D G3DSA:3.40.50.720 8 216 4.3E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS21415 a7b6492a5e1da20626eb32e8f2978a7e 290 Gene3D G3DSA:1.10.260.40 8 71 1.1E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS21415 a7b6492a5e1da20626eb32e8f2978a7e 290 SUPERFAMILY SSF47413 10 71 1.55E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS21415 a7b6492a5e1da20626eb32e8f2978a7e 290 Pfam PF13560 Helix-turn-helix domain 16 76 2.6E-12 T 06-07-2017 SMD11_RS08380 b10ee7604b882df15fe5f1242dfa770d 264 SMART SM01043 105 250 1.7E-42 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS08380 b10ee7604b882df15fe5f1242dfa770d 264 SUPERFAMILY SSF46894 11 97 7.65E-12 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS08380 b10ee7604b882df15fe5f1242dfa770d 264 SUPERFAMILY SSF48452 103 258 1.18E-29 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS08380 b10ee7604b882df15fe5f1242dfa770d 264 SMART SM00862 24 98 4.8E-7 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS08380 b10ee7604b882df15fe5f1242dfa770d 264 Pfam PF00486 Transcriptional regulatory protein, C terminal 35 97 6.7E-8 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS08380 b10ee7604b882df15fe5f1242dfa770d 264 Gene3D G3DSA:1.10.10.10 19 99 2.2E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08380 b10ee7604b882df15fe5f1242dfa770d 264 Pfam PF03704 Bacterial transcriptional activator domain 105 250 1.8E-39 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS25285 320f88d3add7865e7b543483bb74ee2a 365 SUPERFAMILY SSF51679 10 331 3.79E-63 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS25285 320f88d3add7865e7b543483bb74ee2a 365 Pfam PF00296 Luciferase-like monooxygenase 10 308 5.3E-35 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS25285 320f88d3add7865e7b543483bb74ee2a 365 Gene3D G3DSA:3.20.20.30 10 331 1.5E-75 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS25285 320f88d3add7865e7b543483bb74ee2a 365 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 11 331 6.5E-99 T 06-07-2017 IPR019949 Luciferase family oxidoreductase, group 1 SMD11_RS29150 190f474fa04773c7ab4a0ea3d19ccb2b 666 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 302 431 4.3E-18 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS29150 190f474fa04773c7ab4a0ea3d19ccb2b 666 SMART SM00644 293 430 1.7E-39 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS29150 190f474fa04773c7ab4a0ea3d19ccb2b 666 Gene3D G3DSA:3.40.80.10 292 443 6.5E-36 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS29150 190f474fa04773c7ab4a0ea3d19ccb2b 666 Gene3D G3DSA:1.10.530.10 55 117 6.6E-6 T 06-07-2017 SMD11_RS29150 190f474fa04773c7ab4a0ea3d19ccb2b 666 Gene3D G3DSA:1.10.530.10 163 209 6.6E-6 T 06-07-2017 SMD11_RS29150 190f474fa04773c7ab4a0ea3d19ccb2b 666 SUPERFAMILY SSF53955 36 123 1.41E-5 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS29150 190f474fa04773c7ab4a0ea3d19ccb2b 666 SUPERFAMILY SSF55846 289 445 1.31E-36 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS32685 4b2af0f3f92a520dc8c3be6209102e4b 313 Gene3D G3DSA:3.40.50.1820 50 302 9.7E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32685 4b2af0f3f92a520dc8c3be6209102e4b 313 SUPERFAMILY SSF53474 67 258 3.62E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32685 4b2af0f3f92a520dc8c3be6209102e4b 313 Pfam PF00561 alpha/beta hydrolase fold 75 179 6.9E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS03535 16d55659832738a3d1af0afbb0ed2685 506 Gene3D G3DSA:1.10.1060.10 331 416 1.8E-10 T 06-07-2017 SMD11_RS03535 16d55659832738a3d1af0afbb0ed2685 506 Gene3D G3DSA:3.40.50.10420 214 317 2.3E-44 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain SMD11_RS03535 16d55659832738a3d1af0afbb0ed2685 506 Gene3D G3DSA:3.40.50.10420 83 146 2.3E-44 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain SMD11_RS03535 16d55659832738a3d1af0afbb0ed2685 506 Pfam PF13183 4Fe-4S dicluster domain 332 401 5.8E-9 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD11_RS03535 16d55659832738a3d1af0afbb0ed2685 506 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 335 346 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD11_RS03535 16d55659832738a3d1af0afbb0ed2685 506 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 90 315 7.8E-46 T 06-07-2017 IPR003741 LUD domain SMD11_RS03535 16d55659832738a3d1af0afbb0ed2685 506 SUPERFAMILY SSF100950 153 317 1.93E-34 T 06-07-2017 SMD11_RS03535 16d55659832738a3d1af0afbb0ed2685 506 SUPERFAMILY SSF100950 83 107 1.93E-34 T 06-07-2017 SMD11_RS03535 16d55659832738a3d1af0afbb0ed2685 506 SUPERFAMILY SSF54862 313 416 1.42E-13 T 06-07-2017 SMD11_RS03535 16d55659832738a3d1af0afbb0ed2685 506 Pfam PF11870 Domain of unknown function (DUF3390) 429 500 1.2E-13 T 06-07-2017 IPR024569 4Fe-4S binding protein, C-terminal SMD11_RS07435 3c9bfdc8b9d4b3b2b79351cfb3dc845a 238 Gene3D G3DSA:3.30.70.1030 24 139 9.6E-27 T 06-07-2017 SMD11_RS07435 3c9bfdc8b9d4b3b2b79351cfb3dc845a 238 SUPERFAMILY SSF54909 18 237 1.05E-74 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS07435 3c9bfdc8b9d4b3b2b79351cfb3dc845a 238 Gene3D G3DSA:3.30.70.1100 140 237 1.3E-40 T 06-07-2017 SMD11_RS07435 3c9bfdc8b9d4b3b2b79351cfb3dc845a 238 Pfam PF06778 Chlorite dismutase 40 227 9.4E-74 T 06-07-2017 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 337 438 4.9E-15 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 Gene3D G3DSA:2.40.37.10 315 462 3.6E-47 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 267 280 - T 06-07-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 419 432 6.4E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 113 125 6.4E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 93 111 6.4E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 317 336 6.4E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 228 241 6.4E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 SUPERFAMILY SSF51419 63 328 7.85E-77 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 52 462 39.615 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 93 111 - T 06-07-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 45 461 3.6E-144 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 SUPERFAMILY SSF50621 303 462 7.74E-49 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 111 128 5.2E-24 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 429 451 5.2E-24 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 346 364 5.2E-24 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 200 209 5.2E-24 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 Gene3D G3DSA:3.20.20.10 71 314 7.2E-92 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS10885 81a0ba0b5c7587f1b152e7245c74402a 463 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 70 327 9.7E-64 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMD11_RS24585 11c86ed550ee42734d08a4332bafd479 162 Gene3D G3DSA:3.40.630.30 10 162 5.1E-37 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS24585 11c86ed550ee42734d08a4332bafd479 162 SUPERFAMILY SSF55729 15 162 3.49E-34 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS24585 11c86ed550ee42734d08a4332bafd479 162 Pfam PF13673 Acetyltransferase (GNAT) domain 84 162 2.2E-15 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS27205 66b9531776e00e1a5d97b952bbb32b84 370 PRINTS PR01755 Bacterial translocase SecF protein signature 237 252 8.0E-22 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD11_RS27205 66b9531776e00e1a5d97b952bbb32b84 370 PRINTS PR01755 Bacterial translocase SecF protein signature 45 60 8.0E-22 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD11_RS27205 66b9531776e00e1a5d97b952bbb32b84 370 PRINTS PR01755 Bacterial translocase SecF protein signature 154 168 8.0E-22 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD11_RS27205 66b9531776e00e1a5d97b952bbb32b84 370 PRINTS PR01755 Bacterial translocase SecF protein signature 202 220 8.0E-22 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD11_RS27205 66b9531776e00e1a5d97b952bbb32b84 370 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 78 291 1.7E-49 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD11_RS27205 66b9531776e00e1a5d97b952bbb32b84 370 SUPERFAMILY SSF82866 117 304 5.62E-28 T 06-07-2017 SMD11_RS27205 66b9531776e00e1a5d97b952bbb32b84 370 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 18 305 24.571 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 SMD11_RS27205 66b9531776e00e1a5d97b952bbb32b84 370 Gene3D G3DSA:1.20.1640.10 108 306 1.1E-18 T 06-07-2017 SMD11_RS27205 66b9531776e00e1a5d97b952bbb32b84 370 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 46 294 8.1E-73 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 SMD11_RS27205 66b9531776e00e1a5d97b952bbb32b84 370 Pfam PF02355 Protein export membrane protein 111 303 1.5E-65 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial SMD11_RS27205 66b9531776e00e1a5d97b952bbb32b84 370 Pfam PF07549 SecD/SecF GG Motif 41 60 7.7E-5 T 06-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site SMD11_RS02925 7df3b90ca6cf454e3c0920f737cc21da 449 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS02925 7df3b90ca6cf454e3c0920f737cc21da 449 Gene3D G3DSA:3.30.200.20 7 83 1.1E-23 T 06-07-2017 SMD11_RS02925 7df3b90ca6cf454e3c0920f737cc21da 449 SUPERFAMILY SSF56112 11 322 9.71E-67 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS02925 7df3b90ca6cf454e3c0920f737cc21da 449 SMART SM00220 14 271 6.8E-61 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS02925 7df3b90ca6cf454e3c0920f737cc21da 449 Gene3D G3DSA:1.10.510.10 84 265 4.7E-46 T 06-07-2017 SMD11_RS02925 7df3b90ca6cf454e3c0920f737cc21da 449 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 43 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS02925 7df3b90ca6cf454e3c0920f737cc21da 449 Pfam PF00069 Protein kinase domain 14 264 1.3E-45 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS18975 3fe3e32cce46df552c021ba52590f2a0 200 Pfam PF03719 Ribosomal protein S5, C-terminal domain 109 179 2.7E-29 T 06-07-2017 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 SMD11_RS18975 3fe3e32cce46df552c021ba52590f2a0 200 ProSitePatterns PS00585 Ribosomal protein S5 signature. 50 82 - T 06-07-2017 IPR018192 Ribosomal protein S5, N-terminal, conserved site SMD11_RS18975 3fe3e32cce46df552c021ba52590f2a0 200 Gene3D G3DSA:3.30.230.10 100 180 1.6E-32 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS18975 3fe3e32cce46df552c021ba52590f2a0 200 SUPERFAMILY SSF54211 101 180 5.82E-25 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS18975 3fe3e32cce46df552c021ba52590f2a0 200 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 185 34.81 T 06-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMD11_RS18975 3fe3e32cce46df552c021ba52590f2a0 200 Pfam PF00333 Ribosomal protein S5, N-terminal domain 35 97 3.4E-27 T 06-07-2017 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 SMD11_RS18975 3fe3e32cce46df552c021ba52590f2a0 200 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 31 185 1.2E-68 T 06-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMD11_RS18975 3fe3e32cce46df552c021ba52590f2a0 200 Gene3D G3DSA:3.30.160.20 33 94 1.6E-28 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain SMD11_RS18975 3fe3e32cce46df552c021ba52590f2a0 200 SUPERFAMILY SSF54768 32 98 1.26E-21 T 06-07-2017 SMD11_RS30625 e4ff8e529f485e4f87eb98481be41449 533 Pfam PF00561 alpha/beta hydrolase fold 117 285 6.6E-13 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS30625 e4ff8e529f485e4f87eb98481be41449 533 Pfam PF08386 TAP-like protein 434 519 4.0E-12 T 06-07-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMD11_RS30625 e4ff8e529f485e4f87eb98481be41449 533 SUPERFAMILY SSF53474 204 301 9.41E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30625 e4ff8e529f485e4f87eb98481be41449 533 SUPERFAMILY SSF53474 79 161 9.41E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30625 e4ff8e529f485e4f87eb98481be41449 533 Gene3D G3DSA:3.40.50.1820 81 163 6.5E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30625 e4ff8e529f485e4f87eb98481be41449 533 Gene3D G3DSA:3.40.50.1820 206 327 6.5E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30625 e4ff8e529f485e4f87eb98481be41449 533 Gene3D G3DSA:3.40.50.1820 388 510 6.5E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30625 e4ff8e529f485e4f87eb98481be41449 533 SUPERFAMILY SSF53474 365 497 2.85E-13 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30625 e4ff8e529f485e4f87eb98481be41449 533 SUPERFAMILY SSF53474 208 275 2.85E-13 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS33250 cf23dfae7069c0db8bcd6a333ef41b33 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 36 97 3.7E-7 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS33250 cf23dfae7069c0db8bcd6a333ef41b33 388 SUPERFAMILY SSF56645 35 225 4.19E-33 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS33250 cf23dfae7069c0db8bcd6a333ef41b33 388 Gene3D G3DSA:1.10.540.10 36 104 8.7E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS33250 cf23dfae7069c0db8bcd6a333ef41b33 388 Gene3D G3DSA:2.40.110.10 126 222 4.3E-14 T 06-07-2017 SMD11_RS33250 cf23dfae7069c0db8bcd6a333ef41b33 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 218 3.0E-10 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS08495 ab35c990692bfdd1305630901a238341 611 Gene3D G3DSA:3.40.50.720 366 518 1.3E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08495 ab35c990692bfdd1305630901a238341 611 Gene3D G3DSA:3.40.50.720 1 43 1.6E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08495 ab35c990692bfdd1305630901a238341 611 Gene3D G3DSA:3.40.50.720 80 146 1.6E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08495 ab35c990692bfdd1305630901a238341 611 Pfam PF02254 TrkA-N domain 369 477 1.1E-19 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SMD11_RS08495 ab35c990692bfdd1305630901a238341 611 Pfam PF02254 TrkA-N domain 77 147 6.2E-9 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SMD11_RS08495 ab35c990692bfdd1305630901a238341 611 SUPERFAMILY SSF51735 365 514 7.09E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08495 ab35c990692bfdd1305630901a238341 611 SUPERFAMILY SSF51735 81 146 1.02E-9 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS16245 fc0cc35ecf1041d54e82d6be3c4b3f74 297 SUPERFAMILY SSF88946 5 85 5.49E-16 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16245 fc0cc35ecf1041d54e82d6be3c4b3f74 297 Gene3D G3DSA:1.10.10.10 115 168 1.1E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16245 fc0cc35ecf1041d54e82d6be3c4b3f74 297 Pfam PF04542 Sigma-70 region 2 11 74 1.4E-13 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16245 fc0cc35ecf1041d54e82d6be3c4b3f74 297 SUPERFAMILY SSF54427 179 290 2.16E-13 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS16245 fc0cc35ecf1041d54e82d6be3c4b3f74 297 Gene3D G3DSA:3.10.450.50 176 287 6.0E-11 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS16245 fc0cc35ecf1041d54e82d6be3c4b3f74 297 SUPERFAMILY SSF88659 108 168 1.18E-8 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16245 fc0cc35ecf1041d54e82d6be3c4b3f74 297 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 169 1.1E-15 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16245 fc0cc35ecf1041d54e82d6be3c4b3f74 297 Gene3D G3DSA:1.10.1740.10 8 86 1.7E-15 T 06-07-2017 SMD11_RS16245 fc0cc35ecf1041d54e82d6be3c4b3f74 297 Pfam PF08281 Sigma-70, region 4 120 166 2.7E-6 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS13090 281d20b8dce36127e76bc4e3c890288f 517 Gene3D G3DSA:3.90.76.10 44 195 9.6E-28 T 06-07-2017 SMD11_RS13090 281d20b8dce36127e76bc4e3c890288f 517 Gene3D G3DSA:3.10.105.10 295 486 2.6E-44 T 06-07-2017 SMD11_RS13090 281d20b8dce36127e76bc4e3c890288f 517 Gene3D G3DSA:3.40.190.10 196 294 7.3E-20 T 06-07-2017 SMD11_RS13090 281d20b8dce36127e76bc4e3c890288f 517 PIRSF PIRSF002741 11 513 1.5E-71 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD11_RS13090 281d20b8dce36127e76bc4e3c890288f 517 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 435 9.9E-62 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain SMD11_RS13090 281d20b8dce36127e76bc4e3c890288f 517 SUPERFAMILY SSF53850 32 514 7.42E-93 T 06-07-2017 SMD11_RS27810 8890df6e2a4228d22db628b444de8561 368 Pfam PF03610 PTS system fructose IIA component 240 355 1.6E-21 T 06-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SMD11_RS27810 8890df6e2a4228d22db628b444de8561 368 SUPERFAMILY SSF101473 4 210 3.4E-50 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMD11_RS27810 8890df6e2a4228d22db628b444de8561 368 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 12 208 4.8E-62 T 06-07-2017 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 SMD11_RS27810 8890df6e2a4228d22db628b444de8561 368 Gene3D G3DSA:3.40.50.510 238 367 5.9E-35 T 06-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SMD11_RS27810 8890df6e2a4228d22db628b444de8561 368 Pfam PF02734 DAK2 domain 34 208 7.6E-48 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMD11_RS27810 8890df6e2a4228d22db628b444de8561 368 SUPERFAMILY SSF53062 239 365 3.01E-23 T 06-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SMD11_RS27810 8890df6e2a4228d22db628b444de8561 368 SMART SM01120 34 209 3.0E-63 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMD11_RS34575 84292d8121ce6b386a903d15178dddce 211 Pfam PF13358 DDE superfamily endonuclease 20 174 2.8E-17 T 06-07-2017 SMD11_RS10340 c9194357b66814382c9fa37c2a1f2495 260 Gene3D G3DSA:1.10.12.10 197 246 6.9E-15 T 06-07-2017 IPR014748 Crontonase, C-terminal SMD11_RS10340 c9194357b66814382c9fa37c2a1f2495 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 248 8.8E-69 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS10340 c9194357b66814382c9fa37c2a1f2495 260 SUPERFAMILY SSF52096 3 252 2.49E-83 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS10340 c9194357b66814382c9fa37c2a1f2495 260 Gene3D G3DSA:3.90.226.10 2 196 5.9E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS10340 c9194357b66814382c9fa37c2a1f2495 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 Pfam PF06421 GTP-binding protein LepA C-terminus 505 610 6.5E-49 T 06-07-2017 IPR013842 GTP-binding protein LepA, C-terminal SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 Gene3D G3DSA:2.40.30.10 211 305 2.1E-21 T 06-07-2017 SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 Hamap MF_00071 Elongation factor 4 [lepA]. 1 614 285.65 T 06-07-2017 IPR006297 Elongation factor 4 GO:0005525 SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 Gene3D G3DSA:3.30.70.870 308 385 3.4E-25 T 06-07-2017 SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 TIGRFAM TIGR01393 lepA: elongation factor 4 19 612 1.5E-293 T 06-07-2017 IPR006297 Elongation factor 4 GO:0005525 SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 PRINTS PR00315 GTP-binding elongation factor signature 143 152 4.1E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 PRINTS PR00315 GTP-binding elongation factor signature 64 72 4.1E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 PRINTS PR00315 GTP-binding elongation factor signature 107 118 4.1E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 PRINTS PR00315 GTP-binding elongation factor signature 91 101 4.1E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 PRINTS PR00315 GTP-binding elongation factor signature 21 34 4.1E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 SUPERFAMILY SSF54980 308 387 1.22E-19 T 06-07-2017 IPR009022 Elongation factor G, III-V domain SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 Gene3D G3DSA:3.40.50.300 15 210 4.4E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 SMART SM00838 417 498 0.001 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 Pfam PF03144 Elongation factor Tu domain 2 222 292 8.7E-9 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 SUPERFAMILY SSF52540 13 241 6.86E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 Gene3D G3DSA:3.30.70.240 417 505 5.0E-21 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 193 1.8E-18 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 SUPERFAMILY SSF54980 415 510 1.06E-23 T 06-07-2017 IPR009022 Elongation factor G, III-V domain SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 Pfam PF00679 Elongation factor G C-terminus 415 501 7.9E-22 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain SMD11_RS22595 42e039958c974d0087fa95e2108eecbb 620 Pfam PF00009 Elongation factor Tu GTP binding domain 19 198 8.7E-51 T 06-07-2017 SMD11_RS31420 1cc97c805bc426b2402e6cb4dba03744 749 Gene3D G3DSA:3.40.50.300 169 299 2.1E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31420 1cc97c805bc426b2402e6cb4dba03744 749 Gene3D G3DSA:3.40.50.300 496 592 2.1E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31420 1cc97c805bc426b2402e6cb4dba03744 749 Gene3D G3DSA:3.40.50.300 593 733 1.8E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31420 1cc97c805bc426b2402e6cb4dba03744 749 SUPERFAMILY SSF52540 342 402 1.63E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31420 1cc97c805bc426b2402e6cb4dba03744 749 SUPERFAMILY SSF52540 168 247 1.63E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31420 1cc97c805bc426b2402e6cb4dba03744 749 SUPERFAMILY SSF52540 510 721 1.63E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31420 1cc97c805bc426b2402e6cb4dba03744 749 Pfam PF13245 Part of AAA domain 182 247 4.6E-17 T 06-07-2017 SMD11_RS02085 024d71c9dcd734fb772cf6f834d8ca75 253 SUPERFAMILY SSF50494 53 91 1.66E-17 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS02085 024d71c9dcd734fb772cf6f834d8ca75 253 SUPERFAMILY SSF50494 117 223 1.66E-17 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS02085 024d71c9dcd734fb772cf6f834d8ca75 253 Pfam PF13365 Trypsin-like peptidase domain 71 214 1.4E-6 T 06-07-2017 SMD11_RS02085 024d71c9dcd734fb772cf6f834d8ca75 253 Gene3D G3DSA:2.40.10.10 169 230 5.0E-5 T 06-07-2017 SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 Gene3D G3DSA:3.40.50.20 2 129 4.3E-50 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 Pfam PF00364 Biotin-requiring enzyme 614 678 5.6E-18 T 06-07-2017 IPR000089 Biotin/lipoyl attachment SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 636 653 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 SUPERFAMILY SSF56059 83 354 4.95E-67 T 06-07-2017 SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 1.8E-43 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 SUPERFAMILY SSF52440 2 113 9.35E-47 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 324 1.1E-74 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 Gene3D G3DSA:3.30.470.20 203 452 3.3E-92 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 Pfam PF02785 Biotin carboxylase C-terminal domain 338 449 4.1E-32 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 SMART SM00878 338 449 1.8E-47 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 SUPERFAMILY SSF51230 610 679 4.58E-20 T 06-07-2017 IPR011053 Single hybrid motif SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 Gene3D G3DSA:3.30.1490.20 130 201 2.1E-24 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 SUPERFAMILY SSF51246 333 451 7.85E-33 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS21735 000f1d7825d6676c672b3878d833ceb5 685 Gene3D G3DSA:2.40.50.100 611 679 5.3E-24 T 06-07-2017 SMD11_RS06535 3470611770d80ca4dbeca0a0eab669da 260 SUPERFAMILY SSF51735 1 256 2.27E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06535 3470611770d80ca4dbeca0a0eab669da 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 3.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06535 3470611770d80ca4dbeca0a0eab669da 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 3.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06535 3470611770d80ca4dbeca0a0eab669da 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 3.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06535 3470611770d80ca4dbeca0a0eab669da 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 3.5E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06535 3470611770d80ca4dbeca0a0eab669da 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 3.5E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06535 3470611770d80ca4dbeca0a0eab669da 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 3.5E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06535 3470611770d80ca4dbeca0a0eab669da 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 3.5E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06535 3470611770d80ca4dbeca0a0eab669da 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 3.5E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06535 3470611770d80ca4dbeca0a0eab669da 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.5E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06535 3470611770d80ca4dbeca0a0eab669da 260 Gene3D G3DSA:3.40.50.720 2 256 6.2E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06535 3470611770d80ca4dbeca0a0eab669da 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 255 2.6E-48 T 06-07-2017 SMD11_RS26535 86d096740a380f605498d70b3a14ea30 375 SUPERFAMILY SSF47413 45 105 2.95E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS26535 86d096740a380f605498d70b3a14ea30 375 Pfam PF00356 Bacterial regulatory proteins, lacI family 49 94 1.0E-13 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS26535 86d096740a380f605498d70b3a14ea30 375 Gene3D G3DSA:3.40.50.2300 99 216 4.5E-26 T 06-07-2017 SMD11_RS26535 86d096740a380f605498d70b3a14ea30 375 Gene3D G3DSA:3.40.50.2300 217 352 1.2E-39 T 06-07-2017 SMD11_RS26535 86d096740a380f605498d70b3a14ea30 375 SUPERFAMILY SSF53822 104 358 1.06E-50 T 06-07-2017 IPR028082 Periplasmic binding protein-like I SMD11_RS26535 86d096740a380f605498d70b3a14ea30 375 SMART SM00354 45 117 5.9E-21 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS26535 86d096740a380f605498d70b3a14ea30 375 Gene3D G3DSA:1.10.260.40 46 98 2.7E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS26535 86d096740a380f605498d70b3a14ea30 375 Pfam PF13377 Periplasmic binding protein-like domain 213 370 3.4E-33 T 06-07-2017 SMD11_RS13410 1f33f1f20e3bc67f723bbdb12f313fee 258 SMART SM00347 98 185 0.0035 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS13410 1f33f1f20e3bc67f723bbdb12f313fee 258 Pfam PF13936 Helix-turn-helix domain 5 45 1.2E-12 T 06-07-2017 IPR025246 Transposase IS30-like HTH domain SMD11_RS13410 1f33f1f20e3bc67f723bbdb12f313fee 258 SMART SM00418 104 186 7.8E-4 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS13410 1f33f1f20e3bc67f723bbdb12f313fee 258 Gene3D G3DSA:1.10.10.10 6 42 9.5E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13410 1f33f1f20e3bc67f723bbdb12f313fee 258 SUPERFAMILY SSF46785 88 172 9.91E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13410 1f33f1f20e3bc67f723bbdb12f313fee 258 Gene3D G3DSA:1.10.10.10 87 165 4.6E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13410 1f33f1f20e3bc67f723bbdb12f313fee 258 Pfam PF12802 MarR family 104 161 6.2E-12 T 06-07-2017 SMD11_RS19240 4ccff57f909962491306e48516761870 303 SUPERFAMILY SSF53850 91 302 6.67E-36 T 06-07-2017 SMD11_RS19240 4ccff57f909962491306e48516761870 303 SUPERFAMILY SSF46785 2 112 2.25E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19240 4ccff57f909962491306e48516761870 303 Gene3D G3DSA:1.10.10.10 2 88 5.9E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19240 4ccff57f909962491306e48516761870 303 Gene3D G3DSA:3.40.190.10 91 186 7.9E-18 T 06-07-2017 SMD11_RS19240 4ccff57f909962491306e48516761870 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.2E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS19240 4ccff57f909962491306e48516761870 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS19240 4ccff57f909962491306e48516761870 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS19240 4ccff57f909962491306e48516761870 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS19240 4ccff57f909962491306e48516761870 303 Pfam PF03466 LysR substrate binding domain 89 301 3.4E-41 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS19240 4ccff57f909962491306e48516761870 303 Gene3D G3DSA:3.40.190.10 187 273 5.5E-28 T 06-07-2017 SMD11_RS30730 6c879fa32f0e9aac0ad361bc586ceaff 157 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 31 80 2.6E-19 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS30730 6c879fa32f0e9aac0ad361bc586ceaff 157 SUPERFAMILY SSF69118 14 153 9.03E-42 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS30730 6c879fa32f0e9aac0ad361bc586ceaff 157 Gene3D G3DSA:1.20.1290.10 14 151 3.0E-47 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS30730 6c879fa32f0e9aac0ad361bc586ceaff 157 Pfam PF02627 Carboxymuconolactone decarboxylase family 17 96 9.7E-21 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS18295 bc5562f32b6820e98781cc4a1b0dda3d 330 Pfam PF00490 Delta-aminolevulinic acid dehydratase 11 328 9.7E-140 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18295 bc5562f32b6820e98781cc4a1b0dda3d 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 198 217 8.1E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18295 bc5562f32b6820e98781cc4a1b0dda3d 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 249 265 8.1E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18295 bc5562f32b6820e98781cc4a1b0dda3d 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 304 323 8.1E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18295 bc5562f32b6820e98781cc4a1b0dda3d 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 129 143 8.1E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18295 bc5562f32b6820e98781cc4a1b0dda3d 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 274 289 8.1E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18295 bc5562f32b6820e98781cc4a1b0dda3d 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 160 179 8.1E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18295 bc5562f32b6820e98781cc4a1b0dda3d 330 Gene3D G3DSA:3.20.20.70 7 330 2.9E-144 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS18295 bc5562f32b6820e98781cc4a1b0dda3d 330 SUPERFAMILY SSF51569 5 330 7.18E-132 T 06-07-2017 SMD11_RS18295 bc5562f32b6820e98781cc4a1b0dda3d 330 SMART SM01004 8 330 1.2E-219 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18295 bc5562f32b6820e98781cc4a1b0dda3d 330 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 249 261 - T 06-07-2017 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18295 bc5562f32b6820e98781cc4a1b0dda3d 330 PIRSF PIRSF001415 2 330 2.1E-148 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS22585 63b94a0b624387d597a5fc518cfcfe36 332 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 15 324 2.6E-33 T 06-07-2017 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 SMD11_RS22585 63b94a0b624387d597a5fc518cfcfe36 332 Pfam PF06144 DNA polymerase III, delta subunit 20 179 5.0E-11 T 06-07-2017 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 SMD11_RS22585 63b94a0b624387d597a5fc518cfcfe36 332 SUPERFAMILY SSF52540 10 189 1.96E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22585 63b94a0b624387d597a5fc518cfcfe36 332 SUPERFAMILY SSF48019 207 326 4.76E-16 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 SMD11_RS22585 63b94a0b624387d597a5fc518cfcfe36 332 Gene3D G3DSA:3.40.50.300 11 109 3.4E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22585 63b94a0b624387d597a5fc518cfcfe36 332 Gene3D G3DSA:1.10.8.60 141 216 7.0E-7 T 06-07-2017 SMD11_RS22585 63b94a0b624387d597a5fc518cfcfe36 332 Gene3D G3DSA:1.20.272.20 217 326 1.2E-4 T 06-07-2017 SMD11_RS08305 e2378102b04da99bfc0d48028c802656 284 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS08305 e2378102b04da99bfc0d48028c802656 284 SMART SM00382 30 208 2.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS08305 e2378102b04da99bfc0d48028c802656 284 Pfam PF00005 ABC transporter 22 159 1.9E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS08305 e2378102b04da99bfc0d48028c802656 284 SUPERFAMILY SSF52540 3 221 2.51E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08305 e2378102b04da99bfc0d48028c802656 284 Gene3D G3DSA:3.40.50.300 2 222 2.5E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27540 6d9bce77d37f75aac0eeb51bcc15e2a8 362 SMART SM00116 285 333 0.41 T 06-07-2017 IPR000644 CBS domain SMD11_RS27540 6d9bce77d37f75aac0eeb51bcc15e2a8 362 SMART SM00116 225 273 0.095 T 06-07-2017 IPR000644 CBS domain SMD11_RS27540 6d9bce77d37f75aac0eeb51bcc15e2a8 362 Pfam PF01595 Domain of unknown function DUF21 8 201 3.5E-41 T 06-07-2017 IPR002550 Domain of unknown function DUF21 SMD11_RS27540 6d9bce77d37f75aac0eeb51bcc15e2a8 362 SUPERFAMILY SSF54631 206 341 6.95E-23 T 06-07-2017 SMD11_RS27540 6d9bce77d37f75aac0eeb51bcc15e2a8 362 Pfam PF00571 CBS domain 284 333 8.0E-5 T 06-07-2017 IPR000644 CBS domain SMD11_RS27540 6d9bce77d37f75aac0eeb51bcc15e2a8 362 Pfam PF00571 CBS domain 226 270 3.6E-4 T 06-07-2017 IPR000644 CBS domain SMD11_RS27540 6d9bce77d37f75aac0eeb51bcc15e2a8 362 Gene3D G3DSA:3.10.580.10 225 332 3.1E-16 T 06-07-2017 SMD11_RS01950 6f9843178b73820b9297ad7e5ad39349 275 SMART SM00342 189 271 1.5E-25 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS01950 6f9843178b73820b9297ad7e5ad39349 275 SUPERFAMILY SSF51215 26 145 3.66E-22 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD11_RS01950 6f9843178b73820b9297ad7e5ad39349 275 SUPERFAMILY SSF46689 177 223 2.0E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS01950 6f9843178b73820b9297ad7e5ad39349 275 Pfam PF02311 AraC-like ligand binding domain 17 146 1.1E-23 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD11_RS01950 6f9843178b73820b9297ad7e5ad39349 275 Gene3D G3DSA:1.10.10.60 178 226 2.6E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS01950 6f9843178b73820b9297ad7e5ad39349 275 Gene3D G3DSA:1.10.10.60 227 271 2.4E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS01950 6f9843178b73820b9297ad7e5ad39349 275 Pfam PF12833 Helix-turn-helix domain 195 272 4.2E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS01950 6f9843178b73820b9297ad7e5ad39349 275 SUPERFAMILY SSF46689 225 272 9.41E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS01950 6f9843178b73820b9297ad7e5ad39349 275 Gene3D G3DSA:2.60.120.280 28 149 7.2E-16 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD11_RS32665 53d64202869670d9c773b1ae6baa18ce 162 Pfam PF12802 MarR family 38 98 3.6E-13 T 06-07-2017 SMD11_RS32665 53d64202869670d9c773b1ae6baa18ce 162 Gene3D G3DSA:1.10.10.10 6 145 3.5E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32665 53d64202869670d9c773b1ae6baa18ce 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 3.8E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS32665 53d64202869670d9c773b1ae6baa18ce 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 3.8E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS32665 53d64202869670d9c773b1ae6baa18ce 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 3.8E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS32665 53d64202869670d9c773b1ae6baa18ce 162 SMART SM00419 51 103 6.7E-4 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMD11_RS32665 53d64202869670d9c773b1ae6baa18ce 162 SMART SM00347 33 134 3.4E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS32665 53d64202869670d9c773b1ae6baa18ce 162 SUPERFAMILY SSF46785 10 145 7.31E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS24695 c356b07353376af4791204c7b729ddf2 241 SUPERFAMILY SSF51366 4 237 1.26E-61 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMD11_RS24695 c356b07353376af4791204c7b729ddf2 241 Gene3D G3DSA:3.20.20.70 5 238 1.7E-70 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS24695 c356b07353376af4791204c7b729ddf2 241 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 4 239 8.7E-119 T 06-07-2017 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 SMD11_RS24695 c356b07353376af4791204c7b729ddf2 241 Pfam PF00977 Histidine biosynthesis protein 6 231 1.2E-61 T 06-07-2017 IPR006062 Histidine biosynthesis GO:0000105 SMD11_RS24695 c356b07353376af4791204c7b729ddf2 241 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 5 238 31.4 T 06-07-2017 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 SMD11_RS00755 80f48ac71aea4c4febc98a8fbcc1a7df 232 TIGRFAM TIGR04539 tRNA_cyclodipep: tRNA-dependent cyclodipeptide synthase 3 221 1.2E-71 T 06-07-2017 IPR030903 Cyclodileucine synthase GO:0016755 SMD11_RS00755 80f48ac71aea4c4febc98a8fbcc1a7df 232 Pfam PF16715 Cyclodipeptide synthase 3 221 3.0E-61 T 06-07-2017 IPR030903 Cyclodileucine synthase GO:0016755 SMD11_RS21705 793688c585b562402c02d50f3d6a1f3d 606 Gene3D G3DSA:3.40.50.10490 246 443 1.3E-67 T 06-07-2017 SMD11_RS21705 793688c585b562402c02d50f3d6a1f3d 606 Gene3D G3DSA:3.60.20.10 2 241 6.1E-74 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS21705 793688c585b562402c02d50f3d6a1f3d 606 Pfam PF01380 SIS domain 296 418 7.3E-29 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 SMD11_RS21705 793688c585b562402c02d50f3d6a1f3d 606 Pfam PF01380 SIS domain 463 586 3.3E-23 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 SMD11_RS21705 793688c585b562402c02d50f3d6a1f3d 606 Pfam PF13522 Glutamine amidotransferase domain 65 193 1.4E-20 T 06-07-2017 SMD11_RS21705 793688c585b562402c02d50f3d6a1f3d 606 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 606 37.559 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SMD11_RS21705 793688c585b562402c02d50f3d6a1f3d 606 SUPERFAMILY SSF53697 246 606 4.36E-98 T 06-07-2017 SMD11_RS21705 793688c585b562402c02d50f3d6a1f3d 606 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 606 1.1E-223 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SMD11_RS21705 793688c585b562402c02d50f3d6a1f3d 606 SUPERFAMILY SSF56235 2 235 1.97E-66 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS21705 793688c585b562402c02d50f3d6a1f3d 606 Gene3D G3DSA:3.40.50.10490 444 606 4.0E-56 T 06-07-2017 SMD11_RS23940 ff96bbb2c9b466d1b12d136c4de222bf 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.5E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23940 ff96bbb2c9b466d1b12d136c4de222bf 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.5E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23940 ff96bbb2c9b466d1b12d136c4de222bf 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.5E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23940 ff96bbb2c9b466d1b12d136c4de222bf 218 SMART SM00421 148 210 7.8E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23940 ff96bbb2c9b466d1b12d136c4de222bf 218 SUPERFAMILY SSF52172 2 164 9.57E-18 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS23940 ff96bbb2c9b466d1b12d136c4de222bf 218 Pfam PF00072 Response regulator receiver domain 3 118 9.4E-12 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS23940 ff96bbb2c9b466d1b12d136c4de222bf 218 Gene3D G3DSA:1.10.10.10 149 215 6.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23940 ff96bbb2c9b466d1b12d136c4de222bf 218 SUPERFAMILY SSF46894 148 196 8.5E-13 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS23940 ff96bbb2c9b466d1b12d136c4de222bf 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 195 1.5E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23940 ff96bbb2c9b466d1b12d136c4de222bf 218 SMART SM00448 1 120 1.2E-7 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS23940 ff96bbb2c9b466d1b12d136c4de222bf 218 Gene3D G3DSA:3.40.50.2300 2 148 2.7E-25 T 06-07-2017 SMD11_RS12450 cfd6afbc3360b9abf025540974884ff3 165 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 10 159 1.3E-43 T 06-07-2017 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 SMD11_RS12450 cfd6afbc3360b9abf025540974884ff3 165 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 161 1.2E-12 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SMD11_RS12450 cfd6afbc3360b9abf025540974884ff3 165 PIRSF PIRSF006092 3 164 1.3E-32 T 06-07-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 SMD11_RS12450 cfd6afbc3360b9abf025540974884ff3 165 SUPERFAMILY SSF54534 85 160 9.03E-11 T 06-07-2017 SMD11_RS12450 cfd6afbc3360b9abf025540974884ff3 165 Hamap MF_00105 Transcription elongation factor GreA [greA]. 7 161 27.513 T 06-07-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 SMD11_RS12450 cfd6afbc3360b9abf025540974884ff3 165 Gene3D G3DSA:1.10.287.180 8 79 4.4E-27 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SMD11_RS12450 cfd6afbc3360b9abf025540974884ff3 165 Pfam PF03449 Transcription elongation factor, N-terminal 10 79 4.7E-25 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SMD11_RS12450 cfd6afbc3360b9abf025540974884ff3 165 SUPERFAMILY SSF46557 8 82 1.15E-22 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SMD11_RS12450 cfd6afbc3360b9abf025540974884ff3 165 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 22 53 - T 06-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 SMD11_RS12450 cfd6afbc3360b9abf025540974884ff3 165 Gene3D G3DSA:3.10.50.30 81 163 5.0E-15 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SMD11_RS20310 862aaf524d9b58528f6c587da66db163 313 SUPERFAMILY SSF53067 3 124 1.3E-32 T 06-07-2017 SMD11_RS20310 862aaf524d9b58528f6c587da66db163 313 SUPERFAMILY SSF53067 134 311 9.99E-40 T 06-07-2017 SMD11_RS20310 862aaf524d9b58528f6c587da66db163 313 Gene3D G3DSA:3.30.420.150 133 312 1.8E-60 T 06-07-2017 SMD11_RS20310 862aaf524d9b58528f6c587da66db163 313 Gene3D G3DSA:3.30.420.40 2 125 9.0E-48 T 06-07-2017 SMD11_RS20310 862aaf524d9b58528f6c587da66db163 313 Pfam PF02541 Ppx/GppA phosphatase family 26 308 8.7E-55 T 06-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 SMD11_RS18695 8afc45a58af47372429b69ca006cb50f 498 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 33 155 3.3E-32 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18695 8afc45a58af47372429b69ca006cb50f 498 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 87 143 7.0E-21 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18695 8afc45a58af47372429b69ca006cb50f 498 SUPERFAMILY SSF143243 24 162 2.88E-38 T 06-07-2017 SMD11_RS18695 8afc45a58af47372429b69ca006cb50f 498 PRINTS PR01217 Proline rich extensin signature 378 399 1.2E-9 T 06-07-2017 SMD11_RS18695 8afc45a58af47372429b69ca006cb50f 498 PRINTS PR01217 Proline rich extensin signature 399 415 1.2E-9 T 06-07-2017 SMD11_RS18695 8afc45a58af47372429b69ca006cb50f 498 PRINTS PR01217 Proline rich extensin signature 468 493 1.2E-9 T 06-07-2017 SMD11_RS18695 8afc45a58af47372429b69ca006cb50f 498 PRINTS PR01217 Proline rich extensin signature 346 362 1.2E-9 T 06-07-2017 SMD11_RS18695 8afc45a58af47372429b69ca006cb50f 498 PRINTS PR01217 Proline rich extensin signature 419 436 1.2E-9 T 06-07-2017 SMD11_RS07745 b35e2d4641381e5dd0d03a38dc6720a7 778 SUPERFAMILY SSF53901 9 249 1.7E-47 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07745 b35e2d4641381e5dd0d03a38dc6720a7 778 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 10 243 3.1E-35 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS07745 b35e2d4641381e5dd0d03a38dc6720a7 778 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 422 638 1.5E-25 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS07745 b35e2d4641381e5dd0d03a38dc6720a7 778 SUPERFAMILY SSF53901 422 645 7.77E-44 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07745 b35e2d4641381e5dd0d03a38dc6720a7 778 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 366 1.6E-33 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS07745 b35e2d4641381e5dd0d03a38dc6720a7 778 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 646 742 1.9E-7 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS07745 b35e2d4641381e5dd0d03a38dc6720a7 778 Gene3D G3DSA:3.40.47.10 261 408 5.6E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07745 b35e2d4641381e5dd0d03a38dc6720a7 778 Gene3D G3DSA:3.40.47.10 656 746 5.0E-11 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07745 b35e2d4641381e5dd0d03a38dc6720a7 778 SUPERFAMILY SSF53901 616 774 6.96E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07745 b35e2d4641381e5dd0d03a38dc6720a7 778 SMART SM00825 Beta-ketoacyl synthase 11 408 8.8E-12 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS07745 b35e2d4641381e5dd0d03a38dc6720a7 778 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 159 175 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS07745 b35e2d4641381e5dd0d03a38dc6720a7 778 Gene3D G3DSA:3.40.47.10 11 256 3.7E-46 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07745 b35e2d4641381e5dd0d03a38dc6720a7 778 Gene3D G3DSA:3.40.47.10 424 651 5.6E-39 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07745 b35e2d4641381e5dd0d03a38dc6720a7 778 SUPERFAMILY SSF53901 217 409 8.26E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS12425 440cee07a76911ed39eab1807da17098 207 Gene3D G3DSA:1.10.10.60 19 71 4.3E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS12425 440cee07a76911ed39eab1807da17098 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 1.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS12425 440cee07a76911ed39eab1807da17098 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 1.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS12425 440cee07a76911ed39eab1807da17098 207 SUPERFAMILY SSF46689 18 74 3.54E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS12425 440cee07a76911ed39eab1807da17098 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 74 6.8E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS12425 440cee07a76911ed39eab1807da17098 207 Gene3D G3DSA:1.10.357.10 72 205 1.0E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS27190 61424fac1304b0f3ae462f2a3be616af 357 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 264 339 3.0E-22 T 06-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 SMD11_RS27190 61424fac1304b0f3ae462f2a3be616af 357 SUPERFAMILY SSF46785 269 342 5.44E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27190 61424fac1304b0f3ae462f2a3be616af 357 SMART SM00382 63 196 6.7E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS27190 61424fac1304b0f3ae462f2a3be616af 357 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 357 159.54 T 06-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 SMD11_RS27190 61424fac1304b0f3ae462f2a3be616af 357 Gene3D G3DSA:3.40.50.300 32 184 8.7E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27190 61424fac1304b0f3ae462f2a3be616af 357 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 265 338 1.4E-29 T 06-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 SMD11_RS27190 61424fac1304b0f3ae462f2a3be616af 357 Gene3D G3DSA:1.10.10.10 269 339 3.5E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27190 61424fac1304b0f3ae462f2a3be616af 357 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 36 338 4.4E-135 T 06-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 SMD11_RS27190 61424fac1304b0f3ae462f2a3be616af 357 Gene3D G3DSA:1.10.8.60 195 267 8.8E-32 T 06-07-2017 SMD11_RS27190 61424fac1304b0f3ae462f2a3be616af 357 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 16 247 1.3E-109 T 06-07-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 SMD11_RS27190 61424fac1304b0f3ae462f2a3be616af 357 SUPERFAMILY SSF52540 32 263 2.7E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23580 b9008e490db897060abe5b955044ea56 201 SUPERFAMILY SSF46894 124 201 5.1E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS23580 b9008e490db897060abe5b955044ea56 201 SMART SM00448 2 115 8.2E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS23580 b9008e490db897060abe5b955044ea56 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 1.2E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23580 b9008e490db897060abe5b955044ea56 201 ProSitePatterns PS00622 LuxR-type HTH domain signature. 155 182 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23580 b9008e490db897060abe5b955044ea56 201 SUPERFAMILY SSF52172 1 129 2.13E-30 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS23580 b9008e490db897060abe5b955044ea56 201 Gene3D G3DSA:1.10.10.10 144 201 6.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23580 b9008e490db897060abe5b955044ea56 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 2.4E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23580 b9008e490db897060abe5b955044ea56 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 2.4E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23580 b9008e490db897060abe5b955044ea56 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 2.4E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23580 b9008e490db897060abe5b955044ea56 201 SMART SM00421 138 195 3.1E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23580 b9008e490db897060abe5b955044ea56 201 Gene3D G3DSA:3.40.50.2300 1 143 6.9E-35 T 06-07-2017 SMD11_RS23580 b9008e490db897060abe5b955044ea56 201 Pfam PF00072 Response regulator receiver domain 5 115 1.5E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS28310 ab0cef42e39fb8927b8e34204e74e8e0 519 Gene3D G3DSA:3.60.110.10 218 474 2.0E-36 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS28310 ab0cef42e39fb8927b8e34204e74e8e0 519 SUPERFAMILY SSF56317 218 481 2.75E-43 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS28310 ab0cef42e39fb8927b8e34204e74e8e0 519 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 70 449 3.0E-87 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 SMD11_RS28310 ab0cef42e39fb8927b8e34204e74e8e0 519 Pfam PF00795 Carbon-nitrogen hydrolase 224 469 4.3E-21 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS28310 ab0cef42e39fb8927b8e34204e74e8e0 519 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 15 487 16.135 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 SMD11_RS09310 3177fce0710ddb40c4d0c706ad302ab0 320 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 37 101 2.2E-8 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS09310 3177fce0710ddb40c4d0c706ad302ab0 320 SUPERFAMILY SSF50129 7 159 3.65E-37 T 06-07-2017 IPR011032 GroES-like SMD11_RS09310 3177fce0710ddb40c4d0c706ad302ab0 320 SMART SM00829 19 317 1.8E-49 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS09310 3177fce0710ddb40c4d0c706ad302ab0 320 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 154 175 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMD11_RS09310 3177fce0710ddb40c4d0c706ad302ab0 320 SUPERFAMILY SSF51735 126 253 1.31E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS09310 3177fce0710ddb40c4d0c706ad302ab0 320 Pfam PF13602 Zinc-binding dehydrogenase 196 317 2.0E-27 T 06-07-2017 SMD11_RS09310 3177fce0710ddb40c4d0c706ad302ab0 320 Gene3D G3DSA:3.40.50.720 160 243 3.5E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS09310 3177fce0710ddb40c4d0c706ad302ab0 320 Gene3D G3DSA:3.90.180.10 9 159 5.5E-48 T 06-07-2017 IPR011032 GroES-like SMD11_RS12715 1cf789d28db7f5c39586d13b7f11f9a1 494 Gene3D G3DSA:1.10.287.130 251 313 1.7E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS12715 1cf789d28db7f5c39586d13b7f11f9a1 494 SMART SM00388 260 327 1.0E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS12715 1cf789d28db7f5c39586d13b7f11f9a1 494 SUPERFAMILY SSF55874 317 474 9.56E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS12715 1cf789d28db7f5c39586d13b7f11f9a1 494 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 368 475 5.9E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS12715 1cf789d28db7f5c39586d13b7f11f9a1 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 473 1.2E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS12715 1cf789d28db7f5c39586d13b7f11f9a1 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 416 1.2E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS12715 1cf789d28db7f5c39586d13b7f11f9a1 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 454 1.2E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS12715 1cf789d28db7f5c39586d13b7f11f9a1 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 430 1.2E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS12715 1cf789d28db7f5c39586d13b7f11f9a1 494 SMART SM00387 367 476 1.1E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS12715 1cf789d28db7f5c39586d13b7f11f9a1 494 Pfam PF00512 His Kinase A (phospho-acceptor) domain 262 327 4.2E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS12715 1cf789d28db7f5c39586d13b7f11f9a1 494 SUPERFAMILY SSF158472 202 250 1.44E-8 T 06-07-2017 SMD11_RS12715 1cf789d28db7f5c39586d13b7f11f9a1 494 Pfam PF00672 HAMP domain 181 248 1.7E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS12715 1cf789d28db7f5c39586d13b7f11f9a1 494 SUPERFAMILY SSF47384 244 327 8.63E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS12715 1cf789d28db7f5c39586d13b7f11f9a1 494 SMART SM00304 200 252 4.2E-15 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS12715 1cf789d28db7f5c39586d13b7f11f9a1 494 Gene3D G3DSA:3.30.565.10 314 474 3.3E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS23525 ad00f6e42bb336f9be8218d7d95dd228 203 Gene3D G3DSA:3.40.50.2300 2 146 2.4E-17 T 06-07-2017 SMD11_RS23525 ad00f6e42bb336f9be8218d7d95dd228 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 196 3.3E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23525 ad00f6e42bb336f9be8218d7d95dd228 203 Pfam PF00072 Response regulator receiver domain 4 117 4.9E-9 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS23525 ad00f6e42bb336f9be8218d7d95dd228 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 4.2E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23525 ad00f6e42bb336f9be8218d7d95dd228 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 4.2E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23525 ad00f6e42bb336f9be8218d7d95dd228 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 4.2E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23525 ad00f6e42bb336f9be8218d7d95dd228 203 SMART SM00448 2 117 4.1E-6 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS23525 ad00f6e42bb336f9be8218d7d95dd228 203 Gene3D G3DSA:1.10.10.10 147 203 2.3E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23525 ad00f6e42bb336f9be8218d7d95dd228 203 SMART SM00421 140 197 1.4E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23525 ad00f6e42bb336f9be8218d7d95dd228 203 SUPERFAMILY SSF46894 134 203 1.29E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS23525 ad00f6e42bb336f9be8218d7d95dd228 203 SUPERFAMILY SSF52172 2 130 5.27E-15 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS04635 9f597b7b1f9cef80c94667d519641d09 610 Pfam PF00501 AMP-binding enzyme 43 489 3.5E-84 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS04635 9f597b7b1f9cef80c94667d519641d09 610 Gene3D G3DSA:3.40.50.980 30 196 3.7E-28 T 06-07-2017 SMD11_RS04635 9f597b7b1f9cef80c94667d519641d09 610 ProSitePatterns PS00455 Putative AMP-binding domain signature. 190 201 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS04635 9f597b7b1f9cef80c94667d519641d09 610 Gene3D G3DSA:2.30.38.10 393 480 4.1E-20 T 06-07-2017 SMD11_RS04635 9f597b7b1f9cef80c94667d519641d09 610 SUPERFAMILY SSF56801 391 593 3.79E-113 T 06-07-2017 SMD11_RS04635 9f597b7b1f9cef80c94667d519641d09 610 SUPERFAMILY SSF56801 20 363 3.79E-113 T 06-07-2017 SMD11_RS04635 9f597b7b1f9cef80c94667d519641d09 610 Gene3D G3DSA:3.30.300.30 481 588 5.4E-13 T 06-07-2017 SMD11_RS04635 9f597b7b1f9cef80c94667d519641d09 610 Gene3D G3DSA:3.40.50.980 197 360 2.1E-36 T 06-07-2017 SMD11_RS27070 079ad65efd365024cbc96c1104478e96 188 Pfam PF11706 CGNR zinc finger 140 183 2.8E-18 T 06-07-2017 IPR021005 Zinc finger, CGNR SMD11_RS27070 079ad65efd365024cbc96c1104478e96 188 SUPERFAMILY SSF160904 2 182 1.15E-49 T 06-07-2017 SMD11_RS27070 079ad65efd365024cbc96c1104478e96 188 Pfam PF07336 Putative stress-induced transcription regulator 12 123 2.4E-15 T 06-07-2017 IPR010852 Putative stress-induced transcription regulator SMD11_RS27070 079ad65efd365024cbc96c1104478e96 188 Gene3D G3DSA:1.10.3300.10 3 184 3.0E-53 T 06-07-2017 IPR023286 ABATE domain SMD11_RS17235 74a1ae42442786727bfdff74f18139f7 219 SUPERFAMILY SSF52172 6 136 8.54E-30 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS17235 74a1ae42442786727bfdff74f18139f7 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17235 74a1ae42442786727bfdff74f18139f7 219 SMART SM00448 7 120 1.4E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS17235 74a1ae42442786727bfdff74f18139f7 219 SMART SM00421 154 211 2.8E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17235 74a1ae42442786727bfdff74f18139f7 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 3.7E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17235 74a1ae42442786727bfdff74f18139f7 219 SUPERFAMILY SSF46894 152 214 4.76E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS17235 74a1ae42442786727bfdff74f18139f7 219 Gene3D G3DSA:1.10.10.10 157 214 8.5E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17235 74a1ae42442786727bfdff74f18139f7 219 Pfam PF00072 Response regulator receiver domain 9 120 4.1E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS17235 74a1ae42442786727bfdff74f18139f7 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 4.3E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17235 74a1ae42442786727bfdff74f18139f7 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 4.3E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17235 74a1ae42442786727bfdff74f18139f7 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 4.3E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17235 74a1ae42442786727bfdff74f18139f7 219 Gene3D G3DSA:3.40.50.2300 5 156 5.1E-37 T 06-07-2017 SMD11_RS18145 162274a236fcbc0696a08a60e495925c 409 SUPERFAMILY SSF103473 12 399 2.22E-46 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS18145 162274a236fcbc0696a08a60e495925c 409 Gene3D G3DSA:1.20.1250.20 14 183 5.5E-22 T 06-07-2017 SMD11_RS18145 162274a236fcbc0696a08a60e495925c 409 Gene3D G3DSA:1.20.1250.20 218 391 8.7E-16 T 06-07-2017 SMD11_RS18145 162274a236fcbc0696a08a60e495925c 409 Pfam PF07690 Major Facilitator Superfamily 14 244 7.3E-20 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS18145 162274a236fcbc0696a08a60e495925c 409 Pfam PF07690 Major Facilitator Superfamily 246 391 6.0E-12 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS03930 296a52694cd9c61875e6daab5460ea9f 424 SUPERFAMILY SSF48264 11 421 3.14E-81 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS03930 296a52694cd9c61875e6daab5460ea9f 424 Pfam PF00067 Cytochrome P450 294 388 1.2E-18 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS03930 296a52694cd9c61875e6daab5460ea9f 424 PRINTS PR00385 P450 superfamily signature 363 372 6.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS03930 296a52694cd9c61875e6daab5460ea9f 424 PRINTS PR00385 P450 superfamily signature 372 383 6.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS03930 296a52694cd9c61875e6daab5460ea9f 424 PRINTS PR00385 P450 superfamily signature 262 279 6.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS03930 296a52694cd9c61875e6daab5460ea9f 424 PRINTS PR00385 P450 superfamily signature 297 308 6.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS03930 296a52694cd9c61875e6daab5460ea9f 424 Gene3D G3DSA:1.10.630.10 9 175 6.5E-108 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS03930 296a52694cd9c61875e6daab5460ea9f 424 Gene3D G3DSA:1.10.630.10 213 421 6.5E-108 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS03930 296a52694cd9c61875e6daab5460ea9f 424 PRINTS PR00359 B-class P450 signature 89 100 5.5E-6 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS03930 296a52694cd9c61875e6daab5460ea9f 424 PRINTS PR00359 B-class P450 signature 151 166 5.5E-6 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS03930 296a52694cd9c61875e6daab5460ea9f 424 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 365 374 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS01250 29d7796e130fbfbb7f96bf439ccede24 339 SUPERFAMILY SSF53686 51 328 4.71E-69 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS01250 29d7796e130fbfbb7f96bf439ccede24 339 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 48 324 4.3E-65 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS01250 29d7796e130fbfbb7f96bf439ccede24 339 Gene3D G3DSA:3.40.50.1100 90 332 4.3E-59 T 06-07-2017 SMD11_RS01250 29d7796e130fbfbb7f96bf439ccede24 339 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 60 73 - T 06-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2053 2168 1.3E-13 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 394 508 1.8E-18 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SUPERFAMILY SSF51735 1107 1303 1.77E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Gene3D G3DSA:3.40.47.10 281 445 6.9E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Gene3D G3DSA:3.40.47.10 1940 2103 1.2E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SUPERFAMILY SSF53901 1674 2049 1.82E-100 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SUPERFAMILY SSF53901 16 381 1.41E-95 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Gene3D G3DSA:3.40.50.720 2748 2966 3.6E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1314 1491 1.6E-64 T 06-07-2017 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2748 2923 1.1E-55 T 06-07-2017 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SUPERFAMILY SSF47336 1584 1692 1.7E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Pfam PF00550 Phosphopantetheine attachment site 1588 1652 1.9E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Pfam PF00550 Phosphopantetheine attachment site 3019 3083 1.7E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SUPERFAMILY SSF51735 2748 2967 2.86E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SUPERFAMILY SSF55048 2321 2378 2.88E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Pfam PF14765 Polyketide synthase dehydratase 901 1157 3.0E-48 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Gene3D G3DSA:1.10.1200.10 3014 3087 3.5E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Gene3D G3DSA:1.10.1200.10 1584 1658 7.2E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SUPERFAMILY SSF55048 665 730 4.58E-13 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SUPERFAMILY SSF51735 2542 2737 1.58E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Gene3D G3DSA:3.40.366.10 730 855 4.0E-67 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Gene3D G3DSA:3.40.366.10 542 662 4.0E-67 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3042 3057 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SUPERFAMILY SSF51735 1311 1583 3.57E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SMART SM00826 901 1056 3.4E-66 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 18 268 1.4E-87 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1677 1927 6.3E-84 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2202 2487 8.6E-106 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 545 843 5.5E-110 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 276 391 1.6E-39 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1935 2050 2.3E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Gene3D G3DSA:3.40.50.720 1309 1510 1.1E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SUPERFAMILY SSF52151 2199 2323 2.59E-69 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SUPERFAMILY SSF52151 2383 2479 2.59E-69 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SMART SM01294 1587 1652 3.8E-5 T 06-07-2017 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SMART SM01294 3017 3083 3.2E-6 T 06-07-2017 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SMART SM00823 Phosphopantetheine attachment site 1586 1656 2.4E-28 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SMART SM00823 Phosphopantetheine attachment site 3016 3087 3.9E-23 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1840 1856 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1611 1626 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SUPERFAMILY SSF52151 543 667 2.33E-63 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SUPERFAMILY SSF52151 731 825 2.33E-63 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SMART SM00825 Beta-ketoacyl synthase 20 444 4.6E-209 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SMART SM00825 Beta-ketoacyl synthase 1679 2103 9.2E-204 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Gene3D G3DSA:3.40.47.10 20 280 1.7E-88 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Gene3D G3DSA:3.40.47.10 1679 1939 7.3E-90 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 SUPERFAMILY SSF47336 3011 3090 9.29E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Gene3D G3DSA:3.30.70.250 665 729 3.7E-9 T 06-07-2017 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Gene3D G3DSA:3.30.70.250 2321 2374 5.7E-5 T 06-07-2017 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Pfam PF08659 KR domain 1314 1489 1.8E-58 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Pfam PF08659 KR domain 2748 2921 2.1E-55 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Pfam PF00698 Acyl transferase domain 545 862 1.6E-81 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Pfam PF00698 Acyl transferase domain 2201 2504 8.0E-58 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Gene3D G3DSA:3.40.366.10 2381 2489 1.8E-72 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS00855 3a8f366da9ee3f3a572fa3436936dd96 3182 Gene3D G3DSA:3.40.366.10 2196 2317 1.8E-72 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 52 302 3.3E-88 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 SUPERFAMILY SSF53901 455 475 3.16E-96 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 SUPERFAMILY SSF53901 50 420 3.16E-96 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 Gene3D G3DSA:1.10.1200.10 872 960 3.7E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 Pfam PF00550 Phosphopantetheine attachment site 886 951 1.3E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 215 231 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 SMART SM00824 Thioesterase 1053 1273 7.8E-35 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 Pfam PF00698 Acyl transferase domain 604 702 7.0E-13 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 SUPERFAMILY SSF53474 1027 1274 4.39E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 SUPERFAMILY SSF53474 913 951 4.39E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 SMART SM00823 Phosphopantetheine attachment site 883 955 5.8E-14 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 SUPERFAMILY SSF52151 601 732 2.88E-16 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 432 544 4.5E-16 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 Gene3D G3DSA:3.40.50.1820 998 1275 5.5E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 Gene3D G3DSA:3.40.366.10 601 702 5.3E-19 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 Gene3D G3DSA:3.40.47.10 49 314 3.0E-88 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 597 855 1.1E-4 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 Pfam PF00975 Thioesterase domain 1070 1270 1.6E-13 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 Pfam PF08990 Erythronolide synthase docking 24 45 9.0E-7 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 SMART SM00825 Beta-ketoacyl synthase 54 480 1.1E-204 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 Gene3D G3DSA:3.40.47.10 315 478 1.5E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00840 f65f69c513d509c38401de1f4e85c0c0 1279 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 310 427 2.6E-40 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS17710 f9c3ac26cd5673e97bfa6309bef5b641 317 SUPERFAMILY SSF46689 248 295 4.93E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS17710 f9c3ac26cd5673e97bfa6309bef5b641 317 Pfam PF12833 Helix-turn-helix domain 215 293 6.4E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS17710 f9c3ac26cd5673e97bfa6309bef5b641 317 Gene3D G3DSA:1.10.10.60 249 294 1.1E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS17710 f9c3ac26cd5673e97bfa6309bef5b641 317 SMART SM00342 209 292 5.0E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS17710 f9c3ac26cd5673e97bfa6309bef5b641 317 Gene3D G3DSA:2.60.120.10 47 91 7.9E-4 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS17710 f9c3ac26cd5673e97bfa6309bef5b641 317 SUPERFAMILY SSF51215 39 170 6.15E-8 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD11_RS19700 be05c9b4e3d50a75831b2b88d7829703 327 Pfam PF13280 WYL domain 143 314 1.9E-27 T 06-07-2017 IPR026881 WYL domain SMD11_RS19700 be05c9b4e3d50a75831b2b88d7829703 327 PIRSF PIRSF016838 1 322 1.4E-25 T 06-07-2017 IPR028349 Protein PafC SMD11_RS19700 be05c9b4e3d50a75831b2b88d7829703 327 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMD11_RS19700 be05c9b4e3d50a75831b2b88d7829703 327 Gene3D G3DSA:1.10.10.10 1 65 2.7E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19700 be05c9b4e3d50a75831b2b88d7829703 327 SUPERFAMILY SSF46785 6 63 3.87E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19700 be05c9b4e3d50a75831b2b88d7829703 327 Pfam PF08279 HTH domain 7 62 3.3E-15 T 06-07-2017 IPR013196 Helix-turn-helix, type 11 SMD11_RS22840 7658677c960117f09be923cea9ef601d 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 2.7E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS22840 7658677c960117f09be923cea9ef601d 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 2.7E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS22840 7658677c960117f09be923cea9ef601d 219 SUPERFAMILY SSF46689 14 98 7.18E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS22840 7658677c960117f09be923cea9ef601d 219 Gene3D G3DSA:1.10.10.60 16 69 1.0E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS22840 7658677c960117f09be923cea9ef601d 219 Gene3D G3DSA:1.10.357.10 70 206 1.1E-15 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS22840 7658677c960117f09be923cea9ef601d 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 69 2.6E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS16875 1926a1c5e2d07ebf7929dd303fea3935 236 SUPERFAMILY SSF53335 26 209 9.78E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS16875 1926a1c5e2d07ebf7929dd303fea3935 236 Gene3D G3DSA:3.40.50.150 26 212 2.3E-61 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS16875 1926a1c5e2d07ebf7929dd303fea3935 236 Pfam PF02527 rRNA small subunit methyltransferase G 24 197 1.4E-54 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SMD11_RS16875 1926a1c5e2d07ebf7929dd303fea3935 236 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 27 195 5.3E-38 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SMD11_RS16875 1926a1c5e2d07ebf7929dd303fea3935 236 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 194 24.563 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SMD11_RS26015 43449563313b3369ce5f84b952b667de 323 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 18 59 1.9E-5 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD11_RS26015 43449563313b3369ce5f84b952b667de 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 322 6.8E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS26015 43449563313b3369ce5f84b952b667de 323 Gene3D G3DSA:1.10.3720.10 98 319 8.4E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS26015 43449563313b3369ce5f84b952b667de 323 SUPERFAMILY SSF161098 103 309 4.97E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS08020 98e0ad3dfd6f362067c5f2bcbc32ae2e 424 TIGRFAM TIGR04516 glycosyl_450act: glycosyltransferase, activator-dependent family 2 419 6.2E-194 T 06-07-2017 IPR030953 Glycosyltransferase, activator-dependent family GO:0016757 SMD11_RS08020 98e0ad3dfd6f362067c5f2bcbc32ae2e 424 Gene3D G3DSA:3.40.50.2000 2 246 7.5E-48 T 06-07-2017 SMD11_RS08020 98e0ad3dfd6f362067c5f2bcbc32ae2e 424 Pfam PF06722 Protein of unknown function (DUF1205) 208 302 4.7E-27 T 06-07-2017 IPR010610 Domain of unknown function DUF1205 SMD11_RS08020 98e0ad3dfd6f362067c5f2bcbc32ae2e 424 Gene3D G3DSA:3.40.50.2000 247 398 5.1E-31 T 06-07-2017 SMD11_RS08020 98e0ad3dfd6f362067c5f2bcbc32ae2e 424 SUPERFAMILY SSF53756 2 56 1.37E-91 T 06-07-2017 SMD11_RS08020 98e0ad3dfd6f362067c5f2bcbc32ae2e 424 SUPERFAMILY SSF53756 90 418 1.37E-91 T 06-07-2017 SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 SMART SM00823 Phosphopantetheine attachment site 1236 1307 5.9E-18 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 SMART SM01294 1237 1303 1.6E-7 T 06-07-2017 SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 Gene3D G3DSA:3.40.47.10 15 279 8.7E-93 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 Gene3D G3DSA:3.40.47.10 280 445 2.5E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 SUPERFAMILY SSF55048 681 739 4.05E-7 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 Pfam PF00698 Acyl transferase domain 560 874 1.7E-78 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 395 519 5.8E-17 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 SMART SM00825 Beta-ketoacyl synthase 20 445 1.5E-198 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 SUPERFAMILY SSF47336 1235 1312 1.57E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1262 1277 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 Pfam PF00550 Phosphopantetheine attachment site 1238 1303 4.6E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 SUPERFAMILY SSF53901 13 385 8.42E-100 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 SUPERFAMILY SSF53901 420 441 8.42E-100 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 Gene3D G3DSA:3.40.366.10 744 859 4.0E-63 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 Gene3D G3DSA:3.40.366.10 556 677 4.0E-63 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 180 196 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 SUPERFAMILY SSF52151 746 843 1.88E-61 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 SUPERFAMILY SSF52151 559 683 1.88E-61 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 SMART SM00826 921 1078 3.3E-4 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 275 390 1.2E-38 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 Gene3D G3DSA:1.10.1200.10 1235 1307 3.1E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 562 855 3.5E-84 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS31555 5c30fe57f3651ec68c5acac2075302f1 1318 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 18 267 9.5E-79 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS06680 f5877b04ca213cd512a885a857b41e63 397 Pfam PF00970 Oxidoreductase FAD-binding domain 185 256 7.6E-9 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SMD11_RS06680 f5877b04ca213cd512a885a857b41e63 397 SUPERFAMILY SSF52343 260 389 2.88E-31 T 06-07-2017 SMD11_RS06680 f5877b04ca213cd512a885a857b41e63 397 Pfam PF00042 Globin 8 105 7.1E-7 T 06-07-2017 IPR000971 Globin GO:0019825|GO:0020037 SMD11_RS06680 f5877b04ca213cd512a885a857b41e63 397 SUPERFAMILY SSF46458 1 144 1.56E-31 T 06-07-2017 IPR009050 Globin-like SMD11_RS06680 f5877b04ca213cd512a885a857b41e63 397 Gene3D G3DSA:1.10.490.10 2 145 1.6E-43 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 SMD11_RS06680 f5877b04ca213cd512a885a857b41e63 397 Gene3D G3DSA:3.40.50.80 262 390 1.3E-28 T 06-07-2017 SMD11_RS06680 f5877b04ca213cd512a885a857b41e63 397 Pfam PF00175 Oxidoreductase NAD-binding domain 269 369 1.3E-8 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMD11_RS06680 f5877b04ca213cd512a885a857b41e63 397 SUPERFAMILY SSF63380 154 255 4.12E-22 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD11_RS06680 f5877b04ca213cd512a885a857b41e63 397 PRINTS PR00409 Phthalate dioxygenase reductase family signature 244 258 6.5E-5 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD11_RS06680 f5877b04ca213cd512a885a857b41e63 397 PRINTS PR00409 Phthalate dioxygenase reductase family signature 266 285 6.5E-5 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD11_RS06680 f5877b04ca213cd512a885a857b41e63 397 PRINTS PR00409 Phthalate dioxygenase reductase family signature 180 190 6.5E-5 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 SMD11_RS06680 f5877b04ca213cd512a885a857b41e63 397 Gene3D G3DSA:2.40.30.10 155 257 1.6E-26 T 06-07-2017 SMD11_RS30855 234f6ceeaf9235d61ed113aa7bbfeae6 701 SUPERFAMILY SSF55718 559 687 7.06E-18 T 06-07-2017 IPR003033 SCP2 sterol-binding domain SMD11_RS30855 234f6ceeaf9235d61ed113aa7bbfeae6 701 SMART SM00849 115 361 1.1E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS30855 234f6ceeaf9235d61ed113aa7bbfeae6 701 Gene3D G3DSA:3.60.15.10 106 203 2.7E-32 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS30855 234f6ceeaf9235d61ed113aa7bbfeae6 701 Gene3D G3DSA:3.60.15.10 267 390 2.7E-32 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS30855 234f6ceeaf9235d61ed113aa7bbfeae6 701 Pfam PF14863 Alkyl sulfatase dimerisation 399 549 1.3E-53 T 06-07-2017 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 SMD11_RS30855 234f6ceeaf9235d61ed113aa7bbfeae6 701 SUPERFAMILY SSF56281 31 551 1.15E-119 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS30855 234f6ceeaf9235d61ed113aa7bbfeae6 701 Pfam PF00753 Metallo-beta-lactamase superfamily 112 360 9.6E-25 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS30855 234f6ceeaf9235d61ed113aa7bbfeae6 701 Pfam PF14864 Alkyl sulfatase C-terminal 558 687 7.7E-22 T 06-07-2017 IPR029229 Alkyl sulfatase, C-terminal SMD11_RS20290 821607ca1909a98f891944fff3cb2728 250 SUPERFAMILY SSF54106 202 249 3.79E-5 T 06-07-2017 IPR018392 LysM domain SMD11_RS20290 821607ca1909a98f891944fff3cb2728 250 SUPERFAMILY SSF53955 41 114 2.03E-30 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS20290 821607ca1909a98f891944fff3cb2728 250 Pfam PF06737 Transglycosylase-like domain 39 114 1.1E-32 T 06-07-2017 IPR010618 Transglycosylase-like SMD11_RS20290 821607ca1909a98f891944fff3cb2728 250 Gene3D G3DSA:1.10.530.10 15 114 1.5E-40 T 06-07-2017 SMD11_RS20290 821607ca1909a98f891944fff3cb2728 250 SMART SM00257 202 250 2.8E-4 T 06-07-2017 IPR018392 LysM domain SMD11_RS20290 821607ca1909a98f891944fff3cb2728 250 Gene3D G3DSA:3.10.350.10 203 249 1.8E-8 T 06-07-2017 IPR018392 LysM domain SMD11_RS20290 821607ca1909a98f891944fff3cb2728 250 Pfam PF01476 LysM domain 203 248 7.9E-8 T 06-07-2017 IPR018392 LysM domain SMD11_RS22720 331b07fc881f04dbf7123bd959a2a4fd 418 Gene3D G3DSA:3.90.550.10 51 284 3.1E-29 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS22720 331b07fc881f04dbf7123bd959a2a4fd 418 Pfam PF13641 Glycosyltransferase like family 2 51 273 4.3E-44 T 06-07-2017 SMD11_RS22720 331b07fc881f04dbf7123bd959a2a4fd 418 SUPERFAMILY SSF53448 45 316 1.29E-46 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS03560 0e98576d06f6c6b01c1989885703d884 407 Gene3D G3DSA:3.40.50.1110 199 402 1.0E-28 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS03560 0e98576d06f6c6b01c1989885703d884 407 SUPERFAMILY SSF52266 198 402 2.29E-43 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS03560 0e98576d06f6c6b01c1989885703d884 407 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 202 397 9.2E-28 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS05055 c6a6f5eb5b910894dfca15cb67dcbbc9 88 Pfam PF01455 HupF/HypC family 1 69 2.5E-28 T 06-07-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMD11_RS05055 c6a6f5eb5b910894dfca15cb67dcbbc9 88 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 78 1.6E-24 T 06-07-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMD11_RS05055 c6a6f5eb5b910894dfca15cb67dcbbc9 88 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 60 72 1.6E-17 T 06-07-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMD11_RS05055 c6a6f5eb5b910894dfca15cb67dcbbc9 88 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 21 37 1.6E-17 T 06-07-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMD11_RS05055 c6a6f5eb5b910894dfca15cb67dcbbc9 88 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 1.6E-17 T 06-07-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMD11_RS05055 c6a6f5eb5b910894dfca15cb67dcbbc9 88 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 42 58 1.6E-17 T 06-07-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC SMD11_RS05055 c6a6f5eb5b910894dfca15cb67dcbbc9 88 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 06-07-2017 IPR019812 Hydrogenase assembly chaperone, conserved site SMD11_RS05055 c6a6f5eb5b910894dfca15cb67dcbbc9 88 SUPERFAMILY SSF159127 1 78 1.09E-24 T 06-07-2017 SMD11_RS02130 efe552c4fc19b18d8902a74231aeaf64 278 SUPERFAMILY SSF103481 184 277 3.4E-9 T 06-07-2017 SMD11_RS02130 efe552c4fc19b18d8902a74231aeaf64 278 SUPERFAMILY SSF103481 41 135 8.5E-7 T 06-07-2017 SMD11_RS09385 1a3b92cadc7833a9bdc667dfad261cf8 340 Pfam PF00962 Adenosine/AMP deaminase 11 328 2.1E-86 T 06-07-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 SMD11_RS09385 1a3b92cadc7833a9bdc667dfad261cf8 340 Gene3D G3DSA:3.20.20.140 7 334 4.9E-97 T 06-07-2017 SMD11_RS09385 1a3b92cadc7833a9bdc667dfad261cf8 340 SUPERFAMILY SSF51556 7 334 1.64E-81 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS09385 1a3b92cadc7833a9bdc667dfad261cf8 340 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 11 330 1.6E-82 T 06-07-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 Pfam PF00330 Aconitase family (aconitate hydratase) 7 457 2.9E-147 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 466 59.168 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 PRINTS PR00415 Aconitase family signature 195 208 6.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 PRINTS PR00415 Aconitase family signature 399 412 6.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 PRINTS PR00415 Aconitase family signature 343 354 6.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 PRINTS PR00415 Aconitase family signature 119 132 6.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 PRINTS PR00415 Aconitase family signature 108 116 6.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 PRINTS PR00415 Aconitase family signature 286 300 6.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 PRINTS PR00415 Aconitase family signature 133 148 6.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 PRINTS PR00415 Aconitase family signature 209 222 6.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 PRINTS PR00415 Aconitase family signature 82 95 6.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 Gene3D G3DSA:3.30.499.10 2 158 3.1E-21 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 Gene3D G3DSA:3.40.1060.10 166 281 2.3E-39 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 Gene3D G3DSA:3.30.499.10 322 466 3.1E-57 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 460 2.1E-224 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 SUPERFAMILY SSF53732 1 465 7.59E-159 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS09805 5e563b4170c5bea00a72ad291d5b4958 480 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMD11_RS21855 20e198e96614d614d3cfb529b60943d7 293 SUPERFAMILY SSF51182 13 253 6.56E-63 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS21855 20e198e96614d614d3cfb529b60943d7 293 Pfam PF04962 KduI/IolB family 12 270 1.1E-90 T 06-07-2017 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 SMD11_RS21855 20e198e96614d614d3cfb529b60943d7 293 Gene3D G3DSA:2.60.120.10 123 276 1.6E-67 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS21855 20e198e96614d614d3cfb529b60943d7 293 Gene3D G3DSA:2.60.120.10 20 122 3.3E-30 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS21855 20e198e96614d614d3cfb529b60943d7 293 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 22 271 1.3E-88 T 06-07-2017 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 SMD11_RS21855 20e198e96614d614d3cfb529b60943d7 293 PIRSF PIRSF036628 5 276 1.3E-102 T 06-07-2017 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 SMD11_RS28810 32462785a6f9f227de79d5321042964e 103 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 28.842 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28810 32462785a6f9f227de79d5321042964e 103 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 102 3.7E-34 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28810 32462785a6f9f227de79d5321042964e 103 Gene3D G3DSA:2.10.150.10 1 102 4.8E-44 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28810 32462785a6f9f227de79d5321042964e 103 SUPERFAMILY SSF51278 1 102 9.42E-43 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28810 32462785a6f9f227de79d5321042964e 103 Pfam PF00699 Urease beta subunit 3 99 5.7E-38 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS22745 b167a381396a3133ee02bb17f61849cc 303 Pfam PF12706 Beta-lactamase superfamily domain 196 264 1.7E-10 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS22745 b167a381396a3133ee02bb17f61849cc 303 Gene3D G3DSA:3.60.15.10 5 301 6.7E-69 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS22745 b167a381396a3133ee02bb17f61849cc 303 Hamap MF_01818 Ribonuclease BN [rbn]. 4 298 30.615 T 06-07-2017 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 SMD11_RS22745 b167a381396a3133ee02bb17f61849cc 303 Pfam PF00753 Metallo-beta-lactamase superfamily 22 105 6.4E-12 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS22745 b167a381396a3133ee02bb17f61849cc 303 SUPERFAMILY SSF56281 5 297 1.02E-59 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS07190 4e9efb9fddf87fd969d504c0154ed7a3 574 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 435 568 1.0E-9 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS07190 4e9efb9fddf87fd969d504c0154ed7a3 574 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 182 337 5.5E-41 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS07190 4e9efb9fddf87fd969d504c0154ed7a3 574 Gene3D G3DSA:3.90.480.10 111 179 5.0E-48 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS07190 4e9efb9fddf87fd969d504c0154ed7a3 574 Gene3D G3DSA:3.90.480.10 351 426 5.0E-48 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS07190 4e9efb9fddf87fd969d504c0154ed7a3 574 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 358 423 7.4E-14 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS07190 4e9efb9fddf87fd969d504c0154ed7a3 574 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 111 172 3.4E-21 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS07190 4e9efb9fddf87fd969d504c0154ed7a3 574 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 480 496 - T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS07190 4e9efb9fddf87fd969d504c0154ed7a3 574 SUPERFAMILY SSF55124 314 446 4.58E-20 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS07190 4e9efb9fddf87fd969d504c0154ed7a3 574 SUPERFAMILY SSF55124 31 181 2.29E-40 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS07190 4e9efb9fddf87fd969d504c0154ed7a3 574 PRINTS PR00397 Sirohaem Fe-binding site signature 480 498 2.9E-9 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS07190 4e9efb9fddf87fd969d504c0154ed7a3 574 PRINTS PR00397 Sirohaem Fe-binding site signature 435 453 2.9E-9 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS07190 4e9efb9fddf87fd969d504c0154ed7a3 574 Gene3D G3DSA:3.30.413.10 432 570 3.2E-36 T 06-07-2017 SMD11_RS07190 4e9efb9fddf87fd969d504c0154ed7a3 574 Gene3D G3DSA:3.30.413.10 182 339 2.9E-45 T 06-07-2017 SMD11_RS07190 4e9efb9fddf87fd969d504c0154ed7a3 574 SUPERFAMILY SSF56014 431 568 5.23E-35 T 06-07-2017 SMD11_RS07190 4e9efb9fddf87fd969d504c0154ed7a3 574 SUPERFAMILY SSF56014 182 341 9.68E-48 T 06-07-2017 SMD11_RS04795 8c70617665ac2b77e0d2a0ef0cbc560a 516 Gene3D G3DSA:3.10.105.10 299 479 1.3E-39 T 06-07-2017 SMD11_RS04795 8c70617665ac2b77e0d2a0ef0cbc560a 516 PIRSF PIRSF002741 11 515 9.5E-64 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD11_RS04795 8c70617665ac2b77e0d2a0ef0cbc560a 516 SUPERFAMILY SSF53850 42 514 1.18E-99 T 06-07-2017 SMD11_RS04795 8c70617665ac2b77e0d2a0ef0cbc560a 516 Gene3D G3DSA:3.90.76.10 59 202 1.9E-27 T 06-07-2017 SMD11_RS04795 8c70617665ac2b77e0d2a0ef0cbc560a 516 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 93 418 6.8E-70 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain SMD11_RS04795 8c70617665ac2b77e0d2a0ef0cbc560a 516 Gene3D G3DSA:3.40.190.10 203 298 5.7E-26 T 06-07-2017 SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 ProSitePatterns PS01095 Chitinases family 18 active site. 519 527 - T 06-07-2017 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 Gene3D G3DSA:2.60.40.10 158 242 5.5E-22 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 Gene3D G3DSA:2.60.40.10 252 336 2.2E-20 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 SMART SM00060 254 328 4.4E-9 T 06-07-2017 IPR003961 Fibronectin type III GO:0005515 SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 SMART SM00060 160 233 4.2E-9 T 06-07-2017 IPR003961 Fibronectin type III GO:0005515 SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 Gene3D G3DSA:3.10.50.10 671 741 6.9E-13 T 06-07-2017 IPR029070 Chitinase insertion domain SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 SMART SM00636 349 768 3.4E-113 T 06-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 Gene3D G3DSA:2.60.40.290 54 153 2.3E-32 T 06-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 SUPERFAMILY SSF49265 158 339 2.24E-25 T 06-07-2017 IPR003961 Fibronectin type III GO:0005515 SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 SMART SM00637 54 151 1.5E-39 T 06-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 Gene3D G3DSA:3.20.20.80 338 670 9.6E-99 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 Gene3D G3DSA:3.20.20.80 745 780 9.6E-99 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 Pfam PF00553 Cellulose binding domain 55 151 1.4E-28 T 06-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 SUPERFAMILY SSF54556 669 740 3.38E-11 T 06-07-2017 IPR029070 Chitinase insertion domain SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 SUPERFAMILY SSF51445 348 667 6.99E-87 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 SUPERFAMILY SSF51445 738 769 6.99E-87 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 SUPERFAMILY SSF49384 50 151 1.4E-28 T 06-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 SMD11_RS10770 d3c61f5579dfbddfbae40a98567df158 781 Pfam PF00704 Glycosyl hydrolases family 18 352 768 1.2E-74 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 SMD11_RS13375 a05440a1a0b67b3c233905312518410b 645 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 156 179 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS13375 a05440a1a0b67b3c233905312518410b 645 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 272 284 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS13375 a05440a1a0b67b3c233905312518410b 645 Pfam PF00069 Protein kinase domain 150 402 1.8E-48 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS13375 a05440a1a0b67b3c233905312518410b 645 SMART SM00220 150 407 3.1E-62 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS13375 a05440a1a0b67b3c233905312518410b 645 Gene3D G3DSA:1.10.510.10 220 402 7.8E-50 T 06-07-2017 SMD11_RS13375 a05440a1a0b67b3c233905312518410b 645 SUPERFAMILY SSF56112 138 425 2.0E-71 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS13375 a05440a1a0b67b3c233905312518410b 645 Gene3D G3DSA:3.30.200.20 143 219 7.3E-23 T 06-07-2017 SMD11_RS04565 58406ad3e6f01dc56a22150b9c895a01 191 SUPERFAMILY SSF88659 105 166 1.79E-11 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS04565 58406ad3e6f01dc56a22150b9c895a01 191 Gene3D G3DSA:1.10.10.10 107 167 5.4E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04565 58406ad3e6f01dc56a22150b9c895a01 191 Pfam PF08281 Sigma-70, region 4 112 162 2.8E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23385 4e143a5be3df19604e33edadb8c62c09 334 SUPERFAMILY SSF46785 7 105 2.2E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23385 4e143a5be3df19604e33edadb8c62c09 334 SUPERFAMILY SSF53850 100 302 3.53E-18 T 06-07-2017 SMD11_RS23385 4e143a5be3df19604e33edadb8c62c09 334 Gene3D G3DSA:3.40.190.10 191 270 3.2E-9 T 06-07-2017 SMD11_RS23385 4e143a5be3df19604e33edadb8c62c09 334 Pfam PF03466 LysR substrate binding domain 99 295 9.0E-19 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS23385 4e143a5be3df19604e33edadb8c62c09 334 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 2.8E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS23385 4e143a5be3df19604e33edadb8c62c09 334 Gene3D G3DSA:3.40.190.10 104 190 3.8E-11 T 06-07-2017 SMD11_RS23385 4e143a5be3df19604e33edadb8c62c09 334 Gene3D G3DSA:1.10.10.10 8 91 2.0E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS09775 7f96657148fc3b9eac96b8022efc9d24 265 Pfam PF01553 Acyltransferase 30 155 1.8E-22 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD11_RS09775 7f96657148fc3b9eac96b8022efc9d24 265 SUPERFAMILY SSF69593 3 227 2.62E-40 T 06-07-2017 SMD11_RS09775 7f96657148fc3b9eac96b8022efc9d24 265 SMART SM00563 41 159 1.5E-32 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD11_RS09775 7f96657148fc3b9eac96b8022efc9d24 265 Gene3D G3DSA:3.40.1130.10 32 221 2.1E-18 T 06-07-2017 SMD11_RS22410 950afad65da9635e56ca77be1a625497 222 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 5 158 3.2E-19 T 06-07-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 SMD11_RS22410 950afad65da9635e56ca77be1a625497 222 Pfam PF04093 rod shape-determining protein MreD 3 155 1.1E-7 T 06-07-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 SUPERFAMILY SSF51161 243 433 9.21E-34 T 06-07-2017 IPR011004 Trimeric LpxA-like SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 SUPERFAMILY SSF53448 269 325 3.68E-80 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 SUPERFAMILY SSF53448 1 237 3.68E-80 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 Pfam PF00483 Nucleotidyl transferase 2 233 8.0E-53 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 Gene3D G3DSA:3.90.550.10 1 237 2.1E-75 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 Gene3D G3DSA:3.40.120.10 384 510 1.9E-13 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 268 301 1.8E-4 T 06-07-2017 IPR001451 Hexapeptide repeat SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 SUPERFAMILY SSF53738 530 634 2.35E-13 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 SUPERFAMILY SSF55957 744 828 7.85E-12 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 384 511 8.0E-15 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 Gene3D G3DSA:3.40.120.10 552 628 7.9E-12 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 640 740 2.3E-4 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 SUPERFAMILY SSF53738 637 741 1.33E-10 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 Gene3D G3DSA:3.30.310.50 752 827 3.2E-11 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 Gene3D G3DSA:3.40.120.10 633 726 3.9E-13 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 Gene3D G3DSA:2.160.10.10 238 366 1.1E-27 T 06-07-2017 SMD11_RS28150 43c6aa889f54fcc10c1a98b95170bd73 831 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 532 632 2.1E-16 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS26255 1f6f487c8de3c639a51828b7451d2af5 404 Gene3D G3DSA:1.20.140.10 240 403 1.2E-44 T 06-07-2017 SMD11_RS26255 1f6f487c8de3c639a51828b7451d2af5 404 Gene3D G3DSA:1.10.540.10 1 132 3.6E-34 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS26255 1f6f487c8de3c639a51828b7451d2af5 404 SUPERFAMILY SSF47203 247 403 4.51E-41 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS26255 1f6f487c8de3c639a51828b7451d2af5 404 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 234 4.8E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS26255 1f6f487c8de3c639a51828b7451d2af5 404 SUPERFAMILY SSF56645 1 262 1.7E-62 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS26255 1f6f487c8de3c639a51828b7451d2af5 404 Gene3D G3DSA:2.40.110.10 133 239 2.6E-37 T 06-07-2017 SMD11_RS26255 1f6f487c8de3c639a51828b7451d2af5 404 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 130 4.9E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS26255 1f6f487c8de3c639a51828b7451d2af5 404 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 249 399 2.7E-33 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS15160 6c1902c840858281a97344c0f8fb47ca 482 Gene3D G3DSA:1.10.260.40 27 80 1.0E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS15160 6c1902c840858281a97344c0f8fb47ca 482 Pfam PF13560 Helix-turn-helix domain 28 84 1.5E-8 T 06-07-2017 SMD11_RS15160 6c1902c840858281a97344c0f8fb47ca 482 SUPERFAMILY SSF47413 27 80 1.94E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS15160 6c1902c840858281a97344c0f8fb47ca 482 Gene3D G3DSA:1.25.40.10 250 463 5.3E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS15160 6c1902c840858281a97344c0f8fb47ca 482 SUPERFAMILY SSF48452 249 447 2.58E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS32725 67877e78745991fff72607e3d1e5b7c1 384 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 2 369 5.2E-86 T 06-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 SMD11_RS32725 67877e78745991fff72607e3d1e5b7c1 384 Gene3D G3DSA:1.20.1250.20 2 179 7.7E-34 T 06-07-2017 SMD11_RS32725 67877e78745991fff72607e3d1e5b7c1 384 Gene3D G3DSA:1.20.1250.20 192 369 4.2E-10 T 06-07-2017 SMD11_RS32725 67877e78745991fff72607e3d1e5b7c1 384 SUPERFAMILY SSF103473 2 372 2.62E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS32725 67877e78745991fff72607e3d1e5b7c1 384 Pfam PF07690 Major Facilitator Superfamily 2 343 4.3E-51 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS32725 67877e78745991fff72607e3d1e5b7c1 384 ProSitePatterns PS00216 Sugar transport proteins signature 1. 50 67 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS25025 c647219275364f63d9f8b6027b8774da 311 SUPERFAMILY SSF51695 38 289 1.07E-63 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD11_RS25025 c647219275364f63d9f8b6027b8774da 311 Gene3D G3DSA:3.20.20.190 18 294 8.3E-71 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD11_RS25025 c647219275364f63d9f8b6027b8774da 311 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 43 284 1.4E-37 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMD11_RS08535 20ed4707cd2cfc0cbcebd31376ec5e47 147 Pfam PF11292 Protein of unknown function (DUF3093) 4 142 1.5E-44 T 06-07-2017 IPR021443 Protein of unknown function DUF3093 SMD11_RS04860 4f7ef4132395c6a91063fdc4f111f08f 198 Gene3D G3DSA:3.90.1140.10 23 191 1.0E-16 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase SMD11_RS04860 4f7ef4132395c6a91063fdc4f111f08f 198 SUPERFAMILY SSF55144 23 177 5.41E-13 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase SMD11_RS04860 4f7ef4132395c6a91063fdc4f111f08f 198 Pfam PF13563 2'-5' RNA ligase superfamily 30 176 2.3E-28 T 06-07-2017 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SUPERFAMILY SSF52151 529 656 1.39E-63 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SUPERFAMILY SSF52151 720 810 1.39E-63 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SMART SM00825 Beta-ketoacyl synthase 8 431 2.3E-168 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 532 822 5.9E-100 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SUPERFAMILY SSF47336 2368 2446 3.66E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Pfam PF08242 Methyltransferase domain 1374 1474 1.2E-9 T 06-07-2017 IPR013217 Methyltransferase type 12 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Pfam PF14765 Polyketide synthase dehydratase 887 1157 5.8E-52 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 255 1.4E-80 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Gene3D G3DSA:3.40.50.720 2091 2276 2.1E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Gene3D G3DSA:3.40.50.720 2356 2372 2.1E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2092 2274 4.9E-49 T 06-07-2017 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SUPERFAMILY SSF50129 1756 1891 3.8E-28 T 06-07-2017 IPR011032 GroES-like SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SUPERFAMILY SSF53335 1344 1526 1.47E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SMART SM00826 887 1046 1.7E-26 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Gene3D G3DSA:3.40.47.10 4 267 6.0E-90 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SMART SM00829 1754 2068 8.7E-128 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Gene3D G3DSA:3.40.47.10 268 430 4.4E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SUPERFAMILY SSF55048 654 718 6.28E-9 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Pfam PF00550 Phosphopantetheine attachment site 2373 2439 4.1E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 263 379 3.0E-37 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Gene3D G3DSA:3.40.366.10 718 823 2.1E-69 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Gene3D G3DSA:3.40.366.10 524 650 2.1E-69 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Pfam PF08659 KR domain 2092 2272 3.3E-57 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Pfam PF00698 Acyl transferase domain 531 822 3.3E-68 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Gene3D G3DSA:3.90.180.10 1759 1892 9.5E-40 T 06-07-2017 IPR011032 GroES-like SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Gene3D G3DSA:3.40.50.150 1359 1525 3.5E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SUPERFAMILY SSF51735 1550 1728 2.3E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 383 495 3.0E-15 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SMART SM01294 2372 2439 0.0017 T 06-07-2017 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 168 184 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SMART SM00823 Phosphopantetheine attachment site 2371 2443 1.1E-8 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Gene3D G3DSA:3.40.50.720 1893 1986 1.2E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SUPERFAMILY SSF53901 405 427 4.88E-87 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SUPERFAMILY SSF53901 4 375 4.88E-87 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Gene3D G3DSA:3.30.70.250 652 708 5.8E-5 T 06-07-2017 SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SUPERFAMILY SSF51735 1858 2013 3.95E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Gene3D G3DSA:1.10.1200.10 2373 2444 3.1E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 SUPERFAMILY SSF51735 2090 2312 3.21E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30470 7a251a126fcd0464f1061fe2e7206c4a 2450 Pfam PF00107 Zinc-binding dehydrogenase 1898 2018 3.3E-22 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS16220 ffa11d2efe1565c87a324e6eccf37f76 371 SUPERFAMILY SSF50494 186 364 5.51E-30 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS16220 ffa11d2efe1565c87a324e6eccf37f76 371 Gene3D G3DSA:2.40.10.10 265 358 5.7E-25 T 06-07-2017 SMD11_RS16220 ffa11d2efe1565c87a324e6eccf37f76 371 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 336 350 7.1E-30 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS16220 ffa11d2efe1565c87a324e6eccf37f76 371 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 203 217 7.1E-30 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS16220 ffa11d2efe1565c87a324e6eccf37f76 371 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 312 335 7.1E-30 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS16220 ffa11d2efe1565c87a324e6eccf37f76 371 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 293 310 7.1E-30 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS16220 ffa11d2efe1565c87a324e6eccf37f76 371 Pfam PF00089 Trypsin 203 362 3.3E-11 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD11_RS16220 ffa11d2efe1565c87a324e6eccf37f76 371 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 321 332 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site SMD11_RS16220 ffa11d2efe1565c87a324e6eccf37f76 371 Gene3D G3DSA:2.40.10.10 172 264 7.0E-22 T 06-07-2017 SMD11_RS16220 ffa11d2efe1565c87a324e6eccf37f76 371 Pfam PF02983 Alpha-lytic protease prodomain 117 149 4.1E-5 T 06-07-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMD11_RS32125 1ce0e3270a5540dd6840f427d2700437 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32125 1ce0e3270a5540dd6840f427d2700437 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32125 1ce0e3270a5540dd6840f427d2700437 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32125 1ce0e3270a5540dd6840f427d2700437 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32125 1ce0e3270a5540dd6840f427d2700437 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32125 1ce0e3270a5540dd6840f427d2700437 242 Gene3D G3DSA:3.40.50.720 6 199 2.8E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32125 1ce0e3270a5540dd6840f427d2700437 242 SUPERFAMILY SSF51735 1 229 2.91E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32125 1ce0e3270a5540dd6840f427d2700437 242 Pfam PF00106 short chain dehydrogenase 8 195 3.9E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16765 1eaeacc3af21118a00dc1425ab8f85de 78 SUPERFAMILY SSF46911 5 75 4.05E-28 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16765 1eaeacc3af21118a00dc1425ab8f85de 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 75 1.2E-29 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16765 1eaeacc3af21118a00dc1425ab8f85de 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 23 73 3.0E-24 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16765 1eaeacc3af21118a00dc1425ab8f85de 78 Pfam PF01084 Ribosomal protein S18 21 71 9.7E-24 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16765 1eaeacc3af21118a00dc1425ab8f85de 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 76 20.461 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16765 1eaeacc3af21118a00dc1425ab8f85de 78 Gene3D G3DSA:4.10.640.10 11 75 1.1E-31 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16765 1eaeacc3af21118a00dc1425ab8f85de 78 ProSitePatterns PS00057 Ribosomal protein S18 signature. 24 47 - T 06-07-2017 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16765 1eaeacc3af21118a00dc1425ab8f85de 78 PRINTS PR00974 Ribosomal protein S18 family signature 63 73 8.4E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16765 1eaeacc3af21118a00dc1425ab8f85de 78 PRINTS PR00974 Ribosomal protein S18 family signature 31 41 8.4E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16765 1eaeacc3af21118a00dc1425ab8f85de 78 PRINTS PR00974 Ribosomal protein S18 family signature 41 48 8.4E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16765 1eaeacc3af21118a00dc1425ab8f85de 78 PRINTS PR00974 Ribosomal protein S18 family signature 49 63 8.4E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS28250 ce4a4bc3559916fd30778143f18092e0 305 Gene3D G3DSA:3.40.190.10 90 180 3.0E-20 T 06-07-2017 SMD11_RS28250 ce4a4bc3559916fd30778143f18092e0 305 Gene3D G3DSA:1.10.10.10 1 87 1.1E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28250 ce4a4bc3559916fd30778143f18092e0 305 Gene3D G3DSA:3.40.190.10 181 265 8.7E-24 T 06-07-2017 SMD11_RS28250 ce4a4bc3559916fd30778143f18092e0 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.3E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS28250 ce4a4bc3559916fd30778143f18092e0 305 SUPERFAMILY SSF46785 1 111 1.49E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28250 ce4a4bc3559916fd30778143f18092e0 305 SUPERFAMILY SSF53850 89 298 1.56E-36 T 06-07-2017 SMD11_RS28250 ce4a4bc3559916fd30778143f18092e0 305 Pfam PF03466 LysR substrate binding domain 87 294 1.7E-40 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS33005 82d0e04705e0050f655ab014188ccc84 428 Pfam PF00009 Elongation factor Tu GTP binding domain 10 193 5.4E-39 T 06-07-2017 SMD11_RS33005 82d0e04705e0050f655ab014188ccc84 428 SUPERFAMILY SSF50465 317 417 1.25E-24 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SMD11_RS33005 82d0e04705e0050f655ab014188ccc84 428 SUPERFAMILY SSF52540 8 227 1.38E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS33005 82d0e04705e0050f655ab014188ccc84 428 Gene3D G3DSA:2.40.30.10 224 349 6.3E-20 T 06-07-2017 SMD11_RS33005 82d0e04705e0050f655ab014188ccc84 428 Gene3D G3DSA:3.40.50.300 7 212 6.3E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS33005 82d0e04705e0050f655ab014188ccc84 428 SUPERFAMILY SSF50447 225 312 4.01E-18 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS33005 82d0e04705e0050f655ab014188ccc84 428 PRINTS PR00315 GTP-binding elongation factor signature 143 152 4.0E-12 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS33005 82d0e04705e0050f655ab014188ccc84 428 PRINTS PR00315 GTP-binding elongation factor signature 11 24 4.0E-12 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS33005 82d0e04705e0050f655ab014188ccc84 428 PRINTS PR00315 GTP-binding elongation factor signature 70 78 4.0E-12 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS33005 82d0e04705e0050f655ab014188ccc84 428 PRINTS PR00315 GTP-binding elongation factor signature 90 100 4.0E-12 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS33005 82d0e04705e0050f655ab014188ccc84 428 PRINTS PR00315 GTP-binding elongation factor signature 106 117 4.0E-12 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS33005 82d0e04705e0050f655ab014188ccc84 428 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 10 417 2.1E-161 T 06-07-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMD11_RS33005 82d0e04705e0050f655ab014188ccc84 428 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 63 78 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site SMD11_RS18310 8916eeadb3fa124f7757da79916c0de3 581 Gene3D G3DSA:1.10.10.350 488 580 4.8E-21 T 06-07-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMD11_RS18310 8916eeadb3fa124f7757da79916c0de3 581 SUPERFAMILY SSF48163 371 579 4.45E-24 T 06-07-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMD11_RS18310 8916eeadb3fa124f7757da79916c0de3 581 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 218 579 2.8E-52 T 06-07-2017 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 SMD11_RS18310 8916eeadb3fa124f7757da79916c0de3 581 Gene3D G3DSA:2.30.30.300 224 257 3.0E-9 T 06-07-2017 IPR023386 Lysine-tRNA ligase, insertion domain GO:0004824 KEGG: 00970+6.1.1.6 SMD11_RS18310 8916eeadb3fa124f7757da79916c0de3 581 Gene3D G3DSA:3.40.50.620 216 223 5.4E-57 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS18310 8916eeadb3fa124f7757da79916c0de3 581 Gene3D G3DSA:3.40.50.620 21 171 5.4E-57 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS18310 8916eeadb3fa124f7757da79916c0de3 581 Gene3D G3DSA:3.40.50.620 266 319 5.4E-57 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS18310 8916eeadb3fa124f7757da79916c0de3 581 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 9 581 31.503 T 06-07-2017 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 SMD11_RS18310 8916eeadb3fa124f7757da79916c0de3 581 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 49 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS18310 8916eeadb3fa124f7757da79916c0de3 581 SUPERFAMILY SSF52374 213 365 1.53E-49 T 06-07-2017 SMD11_RS18310 8916eeadb3fa124f7757da79916c0de3 581 SUPERFAMILY SSF52374 24 174 1.53E-49 T 06-07-2017 SMD11_RS18310 8916eeadb3fa124f7757da79916c0de3 581 Pfam PF01921 tRNA synthetases class I (K) 10 396 2.5E-127 T 06-07-2017 SMD11_RS16095 6bd27c15c69ae05a60357933b9807eba 161 Gene3D G3DSA:1.10.10.10 5 138 5.3E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16095 6bd27c15c69ae05a60357933b9807eba 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 3.5E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS16095 6bd27c15c69ae05a60357933b9807eba 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 3.5E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS16095 6bd27c15c69ae05a60357933b9807eba 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 3.5E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS16095 6bd27c15c69ae05a60357933b9807eba 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 3.5E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS16095 6bd27c15c69ae05a60357933b9807eba 161 SUPERFAMILY SSF46785 15 141 4.62E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16095 6bd27c15c69ae05a60357933b9807eba 161 Pfam PF12802 MarR family 33 89 1.9E-8 T 06-07-2017 SMD11_RS16095 6bd27c15c69ae05a60357933b9807eba 161 SMART SM00347 25 125 8.8E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS31015 9927ad1d6619c25be3f6334ae95001a3 123 Pfam PF03960 ArsC family 54 115 2.1E-9 T 06-07-2017 IPR006660 Arsenate reductase-like SMD11_RS31015 9927ad1d6619c25be3f6334ae95001a3 123 SUPERFAMILY SSF52833 2 120 4.47E-25 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS31015 9927ad1d6619c25be3f6334ae95001a3 123 Gene3D G3DSA:3.40.30.10 1 122 7.8E-36 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS31155 f76a607af10d5f5d42ef755319a0dc67 1075 SUPERFAMILY SSF52151 220 251 2.79E-18 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS31155 f76a607af10d5f5d42ef755319a0dc67 1075 SUPERFAMILY SSF52151 8 192 2.79E-18 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS31155 f76a607af10d5f5d42ef755319a0dc67 1075 SUPERFAMILY SSF52151 291 310 2.79E-18 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS31155 f76a607af10d5f5d42ef755319a0dc67 1075 Pfam PF11856 Protein of unknown function (DUF3376) 663 813 6.3E-12 T 06-07-2017 IPR024282 Domain of unknown function DUF3376 SMD11_RS31155 f76a607af10d5f5d42ef755319a0dc67 1075 Pfam PF01734 Patatin-like phospholipase 13 303 5.4E-16 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 SMD11_RS22195 b08de82997574dfff34209df2725deb8 573 SUPERFAMILY SSF56300 113 199 1.75E-35 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS22195 b08de82997574dfff34209df2725deb8 573 SUPERFAMILY SSF56300 357 510 1.75E-35 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS22195 b08de82997574dfff34209df2725deb8 573 SUPERFAMILY SSF56300 258 285 1.75E-35 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS22195 b08de82997574dfff34209df2725deb8 573 Pfam PF00149 Calcineurin-like phosphoesterase 114 477 1.4E-8 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 SMD11_RS22195 b08de82997574dfff34209df2725deb8 573 Gene3D G3DSA:3.60.21.10 258 280 2.5E-64 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS22195 b08de82997574dfff34209df2725deb8 573 Gene3D G3DSA:3.60.21.10 112 199 2.5E-64 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS22195 b08de82997574dfff34209df2725deb8 573 Gene3D G3DSA:3.60.21.10 350 516 2.5E-64 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS22195 b08de82997574dfff34209df2725deb8 573 TIGRFAM TIGR03767 P_acnes_RR: metallophosphoesterase, PPA1498 family 78 570 8.9E-212 T 06-07-2017 IPR022506 Metallophosphoesterase, PPA1498 SMD11_RS21725 c98cee4cba26cc7a2bf6612abf86ee92 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD11_RS21725 c98cee4cba26cc7a2bf6612abf86ee92 386 Gene3D G3DSA:1.10.540.10 2 119 4.9E-41 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS21725 c98cee4cba26cc7a2bf6612abf86ee92 386 Gene3D G3DSA:1.20.140.10 226 382 1.6E-64 T 06-07-2017 SMD11_RS21725 c98cee4cba26cc7a2bf6612abf86ee92 386 Gene3D G3DSA:2.40.110.10 121 225 2.1E-34 T 06-07-2017 SMD11_RS21725 c98cee4cba26cc7a2bf6612abf86ee92 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 222 1.1E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS21725 c98cee4cba26cc7a2bf6612abf86ee92 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 382 2.9E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS21725 c98cee4cba26cc7a2bf6612abf86ee92 386 SUPERFAMILY SSF56645 2 247 1.83E-78 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS21725 c98cee4cba26cc7a2bf6612abf86ee92 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 3.3E-37 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS21725 c98cee4cba26cc7a2bf6612abf86ee92 386 SUPERFAMILY SSF47203 232 382 7.73E-50 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS01825 e6e2563671863dd6b10fd1fd687d64eb 299 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 26 274 1.1E-62 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted SMD11_RS01825 e6e2563671863dd6b10fd1fd687d64eb 299 SUPERFAMILY SSF51679 3 266 6.54E-61 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS01825 e6e2563671863dd6b10fd1fd687d64eb 299 Pfam PF00296 Luciferase-like monooxygenase 18 245 3.6E-48 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS01825 e6e2563671863dd6b10fd1fd687d64eb 299 Gene3D G3DSA:3.20.20.30 6 256 7.0E-64 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS17760 a750a29e6a8b1a95b394337ec0c2b1fd 402 TIGRFAM TIGR01814 kynureninase: kynureninase 14 400 9.1E-82 T 06-07-2017 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 SMD11_RS17760 a750a29e6a8b1a95b394337ec0c2b1fd 402 PIRSF PIRSF038800 6 402 1.4E-127 T 06-07-2017 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 SMD11_RS17760 a750a29e6a8b1a95b394337ec0c2b1fd 402 Gene3D G3DSA:3.90.1150.10 261 401 1.3E-47 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS17760 a750a29e6a8b1a95b394337ec0c2b1fd 402 Gene3D G3DSA:3.40.640.10 84 260 4.4E-19 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS17760 a750a29e6a8b1a95b394337ec0c2b1fd 402 Hamap MF_01970 Kynureninase [kynU]. 8 400 33.307 T 06-07-2017 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 SMD11_RS17760 a750a29e6a8b1a95b394337ec0c2b1fd 402 SUPERFAMILY SSF53383 13 400 6.88E-79 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS17760 a750a29e6a8b1a95b394337ec0c2b1fd 402 Pfam PF00266 Aminotransferase class-V 109 345 4.7E-13 T 06-07-2017 IPR000192 Aminotransferase class V domain SMD11_RS21200 0162008e6a46e650b4edfff723f18d6a 442 SUPERFAMILY SSF51690 146 437 6.33E-79 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SMD11_RS21200 0162008e6a46e650b4edfff723f18d6a 442 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 16 426 7.3E-126 T 06-07-2017 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SMD11_RS21200 0162008e6a46e650b4edfff723f18d6a 442 PIRSF PIRSF000484 8 440 2.5E-101 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SMD11_RS21200 0162008e6a46e650b4edfff723f18d6a 442 Gene3D G3DSA:3.20.140.10 13 379 7.4E-89 T 06-07-2017 SMD11_RS21200 0162008e6a46e650b4edfff723f18d6a 442 SUPERFAMILY SSF54675 11 144 4.27E-43 T 06-07-2017 SMD11_RS21200 0162008e6a46e650b4edfff723f18d6a 442 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 163 331 6.3E-5 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SMD11_RS07585 14958a7467e3064959233cb88a42931d 1302 Gene3D G3DSA:1.20.1610.10 849 1018 9.8E-49 T 06-07-2017 SMD11_RS07585 14958a7467e3064959233cb88a42931d 1302 Pfam PF07971 Glycosyl hydrolase family 92 631 1157 4.8E-143 T 06-07-2017 IPR012939 Glycosyl hydrolase family 92 SMD11_RS07585 14958a7467e3064959233cb88a42931d 1302 Gene3D G3DSA:2.70.98.10 418 712 3.3E-74 T 06-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 SMD11_RS07585 14958a7467e3064959233cb88a42931d 1302 Gene3D G3DSA:3.30.2080.10 1019 1166 3.2E-59 T 06-07-2017 SMD11_RS07585 14958a7467e3064959233cb88a42931d 1302 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 429 1160 1.4E-140 T 06-07-2017 IPR005887 Alpha-1,2-mannosidase, putative SMD11_RS07585 14958a7467e3064959233cb88a42931d 1302 Gene3D G3DSA:1.20.1050.60 757 844 2.1E-28 T 06-07-2017 SMD11_RS07585 14958a7467e3064959233cb88a42931d 1302 Gene3D G3DSA:2.60.120.260 108 234 3.2E-13 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS07585 14958a7467e3064959233cb88a42931d 1302 Gene3D G3DSA:2.60.120.260 1220 1299 5.2E-4 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS07585 14958a7467e3064959233cb88a42931d 1302 Pfam PF00754 F5/8 type C domain 110 231 6.0E-12 T 06-07-2017 IPR000421 Coagulation factor 5/8 C-terminal domain SMD11_RS07585 14958a7467e3064959233cb88a42931d 1302 SUPERFAMILY SSF49785 115 221 2.09E-13 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS07585 14958a7467e3064959233cb88a42931d 1302 SUPERFAMILY SSF48208 654 1140 1.7E-13 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 SUPERFAMILY SSF50978 3 269 2.99E-43 T 06-07-2017 IPR017986 WD40-repeat-containing domain GO:0005515 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 Gene3D G3DSA:2.130.10.10 6 244 7.4E-44 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 223 237 - T 06-07-2017 IPR019775 WD40 repeat, conserved site SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 PRINTS PR00320 G protein beta WD-40 repeat signature 463 477 7.8E-6 T 06-07-2017 IPR020472 G-protein beta WD-40 repeat SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 PRINTS PR00320 G protein beta WD-40 repeat signature 143 157 7.8E-6 T 06-07-2017 IPR020472 G-protein beta WD-40 repeat SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 PRINTS PR00320 G protein beta WD-40 repeat signature 223 237 7.8E-6 T 06-07-2017 IPR020472 G-protein beta WD-40 repeat SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 SMART SM00320 76 115 0.18 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 SMART SM00320 478 517 3.6E-4 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 SMART SM00320 1 32 270.0 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 SMART SM00320 437 476 0.25 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 SMART SM00320 117 156 2.6E-6 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 SMART SM00320 197 236 8.9E-4 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 SMART SM00320 35 73 6.6E-4 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 Gene3D G3DSA:2.130.10.10 335 556 1.2E-23 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 SUPERFAMILY SSF50978 200 283 6.71E-27 T 06-07-2017 IPR017986 WD40-repeat-containing domain GO:0005515 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 SUPERFAMILY SSF50978 395 556 6.71E-27 T 06-07-2017 IPR017986 WD40-repeat-containing domain GO:0005515 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 19 33 - T 06-07-2017 IPR019775 WD40 repeat, conserved site SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 Pfam PF00400 WD domain, G-beta repeat 44 73 0.0013 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 Pfam PF00400 WD domain, G-beta repeat 200 236 0.035 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 Pfam PF00400 WD domain, G-beta repeat 120 155 0.0023 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS08395 561fe6da014efb50a75d118f97433402 560 Pfam PF00400 WD domain, G-beta repeat 487 517 0.0028 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS26895 bf968f3f23d09de1d4fe6257d5f5aa69 475 SUPERFAMILY SSF51905 3 192 6.02E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS26895 bf968f3f23d09de1d4fe6257d5f5aa69 475 Gene3D G3DSA:3.50.50.60 102 304 2.9E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS26895 bf968f3f23d09de1d4fe6257d5f5aa69 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 294 1.3E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS26895 bf968f3f23d09de1d4fe6257d5f5aa69 475 SUPERFAMILY SSF51905 145 307 1.57E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS26895 bf968f3f23d09de1d4fe6257d5f5aa69 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 271 278 4.6E-13 T 06-07-2017 SMD11_RS26895 bf968f3f23d09de1d4fe6257d5f5aa69 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 232 246 4.6E-13 T 06-07-2017 SMD11_RS26895 bf968f3f23d09de1d4fe6257d5f5aa69 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 4.6E-13 T 06-07-2017 SMD11_RS26895 bf968f3f23d09de1d4fe6257d5f5aa69 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.6E-13 T 06-07-2017 SMD11_RS26895 bf968f3f23d09de1d4fe6257d5f5aa69 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 3.2E-22 T 06-07-2017 SMD11_RS26895 bf968f3f23d09de1d4fe6257d5f5aa69 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 95 113 3.2E-22 T 06-07-2017 SMD11_RS26895 bf968f3f23d09de1d4fe6257d5f5aa69 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.2E-22 T 06-07-2017 SMD11_RS26895 bf968f3f23d09de1d4fe6257d5f5aa69 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 3.2E-22 T 06-07-2017 SMD11_RS26895 bf968f3f23d09de1d4fe6257d5f5aa69 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 3.2E-22 T 06-07-2017 SMD11_RS26895 bf968f3f23d09de1d4fe6257d5f5aa69 475 Gene3D G3DSA:3.50.50.60 1 101 5.8E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS26895 bf968f3f23d09de1d4fe6257d5f5aa69 475 Pfam PF04324 BFD-like [2Fe-2S] binding domain 421 469 4.1E-13 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain SMD11_RS14600 bbf1c4733bde72c2f29fe668ac3b139e 525 Gene3D G3DSA:3.30.43.10 75 165 4.4E-7 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS14600 bbf1c4733bde72c2f29fe668ac3b139e 525 Gene3D G3DSA:3.30.465.10 166 257 3.4E-13 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS14600 bbf1c4733bde72c2f29fe668ac3b139e 525 Pfam PF08031 Berberine and berberine like 482 524 1.6E-10 T 06-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 SMD11_RS14600 bbf1c4733bde72c2f29fe668ac3b139e 525 Pfam PF01565 FAD binding domain 92 225 4.3E-31 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD11_RS14600 bbf1c4733bde72c2f29fe668ac3b139e 525 SUPERFAMILY SSF56176 65 257 1.21E-50 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS22425 43bfd53944fffef77fc776a95c4a02b8 554 SUPERFAMILY SSF55154 5 207 8.07E-43 T 06-07-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 SMD11_RS22425 43bfd53944fffef77fc776a95c4a02b8 554 Gene3D G3DSA:2.40.320.10 5 208 8.9E-52 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 SMD11_RS22425 43bfd53944fffef77fc776a95c4a02b8 554 Pfam PF01928 CYTH domain 37 180 1.1E-12 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 SMD11_RS22425 43bfd53944fffef77fc776a95c4a02b8 554 SMART SM00880 270 534 1.8E-66 T 06-07-2017 IPR007899 CHAD domain SMD11_RS22425 43bfd53944fffef77fc776a95c4a02b8 554 SMART SM01118 5 206 4.1E-15 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 SMD11_RS22425 43bfd53944fffef77fc776a95c4a02b8 554 Pfam PF05235 CHAD domain 270 502 1.6E-50 T 06-07-2017 IPR007899 CHAD domain SMD11_RS07975 d58399ff20ac4e3e0fb2559b7b8dc751 123 Gene3D G3DSA:1.10.287.1080 1 84 2.7E-19 T 06-07-2017 SMD11_RS07975 d58399ff20ac4e3e0fb2559b7b8dc751 123 SUPERFAMILY SSF101386 1 82 1.87E-26 T 06-07-2017 SMD11_RS07975 d58399ff20ac4e3e0fb2559b7b8dc751 123 Pfam PF12643 MazG-like family 30 84 7.8E-8 T 06-07-2017 IPR025984 MazG-like domain KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 SMD11_RS20385 fa5c257659f275a681694c2449bb1cd4 519 SUPERFAMILY SSF52096 246 518 2.06E-87 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS20385 fa5c257659f275a681694c2449bb1cd4 519 Pfam PF01039 Carboxyl transferase domain 31 516 2.6E-187 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS20385 fa5c257659f275a681694c2449bb1cd4 519 SUPERFAMILY SSF52096 6 259 4.12E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS20385 fa5c257659f275a681694c2449bb1cd4 519 Gene3D G3DSA:3.90.226.10 259 518 8.7E-98 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS20385 fa5c257659f275a681694c2449bb1cd4 519 Gene3D G3DSA:3.90.226.10 12 258 8.1E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS24290 6d17377dd82c3fb6ad5aa738f9a8a42c 598 SUPERFAMILY SSF56801 17 288 2.22E-114 T 06-07-2017 SMD11_RS24290 6d17377dd82c3fb6ad5aa738f9a8a42c 598 SUPERFAMILY SSF56801 337 596 2.22E-114 T 06-07-2017 SMD11_RS24290 6d17377dd82c3fb6ad5aa738f9a8a42c 598 Gene3D G3DSA:3.40.50.980 17 189 8.3E-35 T 06-07-2017 SMD11_RS24290 6d17377dd82c3fb6ad5aa738f9a8a42c 598 Gene3D G3DSA:3.40.50.980 190 283 5.8E-27 T 06-07-2017 SMD11_RS24290 6d17377dd82c3fb6ad5aa738f9a8a42c 598 Gene3D G3DSA:3.40.50.980 334 396 5.8E-27 T 06-07-2017 SMD11_RS24290 6d17377dd82c3fb6ad5aa738f9a8a42c 598 Pfam PF00501 AMP-binding enzyme 23 466 1.6E-99 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS24290 6d17377dd82c3fb6ad5aa738f9a8a42c 598 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS24290 6d17377dd82c3fb6ad5aa738f9a8a42c 598 Gene3D G3DSA:3.30.300.30 464 509 7.0E-5 T 06-07-2017 SMD11_RS24290 6d17377dd82c3fb6ad5aa738f9a8a42c 598 Gene3D G3DSA:2.30.38.10 397 457 6.1E-20 T 06-07-2017 SMD11_RS08600 c04409beb16ad2d336390ae84e821db8 223 Gene3D G3DSA:3.30.60.20 144 194 6.4E-5 T 06-07-2017 SMD11_RS08600 c04409beb16ad2d336390ae84e821db8 223 SUPERFAMILY SSF57716 144 195 2.19E-8 T 06-07-2017 SMD11_RS08600 c04409beb16ad2d336390ae84e821db8 223 Pfam PF00265 Thymidine kinase 4 192 5.7E-22 T 06-07-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 SMD11_RS08600 c04409beb16ad2d336390ae84e821db8 223 SUPERFAMILY SSF52540 1 139 2.38E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08600 c04409beb16ad2d336390ae84e821db8 223 PIRSF PIRSF035805 1 205 1.1E-33 T 06-07-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 SMD11_RS08600 c04409beb16ad2d336390ae84e821db8 223 Gene3D G3DSA:3.40.50.300 2 118 4.8E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05435 4fcbb90c64356341ef2112a1e74fbf74 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 9.5E-13 T 06-07-2017 SMD11_RS05435 4fcbb90c64356341ef2112a1e74fbf74 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 9.5E-13 T 06-07-2017 SMD11_RS05435 4fcbb90c64356341ef2112a1e74fbf74 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 9.5E-13 T 06-07-2017 SMD11_RS05435 4fcbb90c64356341ef2112a1e74fbf74 389 Gene3D G3DSA:3.50.50.60 276 355 9.8E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05435 4fcbb90c64356341ef2112a1e74fbf74 389 Gene3D G3DSA:3.50.50.60 5 176 9.8E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05435 4fcbb90c64356341ef2112a1e74fbf74 389 Pfam PF01494 FAD binding domain 7 350 2.3E-18 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS05435 4fcbb90c64356341ef2112a1e74fbf74 389 SUPERFAMILY SSF51905 6 171 1.69E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05435 4fcbb90c64356341ef2112a1e74fbf74 389 SUPERFAMILY SSF51905 276 362 1.69E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS26300 05b29528854c9369201ed35be81279ac 135 Gene3D G3DSA:3.40.30.10 17 96 8.9E-6 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS30055 b7678749ebc08179ac07bae0216761d3 379 SUPERFAMILY SSF51419 12 230 9.49E-24 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS30055 b7678749ebc08179ac07bae0216761d3 379 Pfam PF14031 Putative serine dehydratase domain 271 364 6.5E-13 T 06-07-2017 IPR026956 D-serine dehydratase-like domain SMD11_RS30055 b7678749ebc08179ac07bae0216761d3 379 SMART SM01119 271 365 3.7E-22 T 06-07-2017 IPR026956 D-serine dehydratase-like domain SMD11_RS30055 b7678749ebc08179ac07bae0216761d3 379 Pfam PF01168 Alanine racemase, N-terminal domain 12 221 9.0E-14 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS30055 b7678749ebc08179ac07bae0216761d3 379 Gene3D G3DSA:3.20.20.10 14 172 5.7E-8 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS21010 9ca1ab0891c047dce5f9015ccfe64e3f 93 Gene3D G3DSA:4.10.520.10 1 91 6.4E-29 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMD11_RS21010 9ca1ab0891c047dce5f9015ccfe64e3f 93 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.5E-27 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD11_RS21010 9ca1ab0891c047dce5f9015ccfe64e3f 93 SMART SM00411 1 91 7.7E-38 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD11_RS21010 9ca1ab0891c047dce5f9015ccfe64e3f 93 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 06-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 SMD11_RS21010 9ca1ab0891c047dce5f9015ccfe64e3f 93 SUPERFAMILY SSF47729 1 91 3.24E-26 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMD11_RS21010 9ca1ab0891c047dce5f9015ccfe64e3f 93 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 2.2E-8 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD11_RS21010 9ca1ab0891c047dce5f9015ccfe64e3f 93 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 2.2E-8 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD11_RS21010 9ca1ab0891c047dce5f9015ccfe64e3f 93 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 2.2E-8 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD11_RS34315 1681c7bf8785e7e9bc16515f26b6653e 369 SUPERFAMILY SSF53474 11 360 1.19E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS34315 1681c7bf8785e7e9bc16515f26b6653e 369 Pfam PF00561 alpha/beta hydrolase fold 44 133 1.4E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS34315 1681c7bf8785e7e9bc16515f26b6653e 369 Gene3D G3DSA:3.40.50.1820 9 359 5.2E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS26530 66458378906c10b706fc92d39ecc822d 251 Gene3D G3DSA:3.60.20.10 3 237 1.0E-86 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS26530 66458378906c10b706fc92d39ecc822d 251 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 234 49.198 T 06-07-2017 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 SMD11_RS26530 66458378906c10b706fc92d39ecc822d 251 SUPERFAMILY SSF56235 10 230 1.77E-45 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS26530 66458378906c10b706fc92d39ecc822d 251 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 230 3.9E-116 T 06-07-2017 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 SMD11_RS26530 66458378906c10b706fc92d39ecc822d 251 Pfam PF00227 Proteasome subunit 25 207 3.2E-29 T 06-07-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 SMD11_RS08615 ffc70c9eac47edbe9c960d7e9083d8ae 940 SMART SM00881 208 309 6.9E-24 T 06-07-2017 IPR003781 CoA-binding GO:0048037 SMD11_RS08615 ffc70c9eac47edbe9c960d7e9083d8ae 940 SUPERFAMILY SSF51735 206 338 2.82E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08615 ffc70c9eac47edbe9c960d7e9083d8ae 940 Gene3D G3DSA:3.40.50.720 195 339 9.0E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08615 ffc70c9eac47edbe9c960d7e9083d8ae 940 Pfam PF13380 CoA binding domain 213 343 2.4E-14 T 06-07-2017 IPR003781 CoA-binding GO:0048037 SMD11_RS08615 ffc70c9eac47edbe9c960d7e9083d8ae 940 Gene3D G3DSA:3.40.630.30 18 182 1.8E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS08615 ffc70c9eac47edbe9c960d7e9083d8ae 940 Pfam PF13549 ATP-grasp domain 715 923 1.7E-53 T 06-07-2017 SMD11_RS08615 ffc70c9eac47edbe9c960d7e9083d8ae 940 Pfam PF00583 Acetyltransferase (GNAT) family 84 167 6.0E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS08615 ffc70c9eac47edbe9c960d7e9083d8ae 940 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 362 498 2.6E-40 T 06-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain SMD11_RS08615 ffc70c9eac47edbe9c960d7e9083d8ae 940 SUPERFAMILY SSF56059 721 917 3.06E-22 T 06-07-2017 SMD11_RS08615 ffc70c9eac47edbe9c960d7e9083d8ae 940 Gene3D G3DSA:3.40.50.261 503 605 6.3E-11 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS08615 ffc70c9eac47edbe9c960d7e9083d8ae 940 SUPERFAMILY SSF52210 507 667 3.79E-16 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS08615 ffc70c9eac47edbe9c960d7e9083d8ae 940 SUPERFAMILY SSF52210 341 503 6.67E-32 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS08615 ffc70c9eac47edbe9c960d7e9083d8ae 940 Gene3D G3DSA:3.40.50.261 340 497 4.7E-32 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS08615 ffc70c9eac47edbe9c960d7e9083d8ae 940 SUPERFAMILY SSF55729 23 174 2.7E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS15530 5e83ef7c2ef55f04f48375837ed3293e 331 Gene3D G3DSA:3.40.50.300 4 237 5.3E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15530 5e83ef7c2ef55f04f48375837ed3293e 331 SUPERFAMILY SSF52540 2 226 2.55E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15530 5e83ef7c2ef55f04f48375837ed3293e 331 Pfam PF02374 Anion-transporting ATPase 6 180 3.7E-18 T 06-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 SMD11_RS32800 df24a3d61dc11396923fe50b6784129a 238 Gene3D G3DSA:1.10.357.10 8 230 1.2E-41 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS32800 df24a3d61dc11396923fe50b6784129a 238 SUPERFAMILY SSF46689 9 83 2.14E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS32800 df24a3d61dc11396923fe50b6784129a 238 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 65 3.7E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS32800 df24a3d61dc11396923fe50b6784129a 238 SUPERFAMILY SSF48498 94 230 3.11E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS07170 08c40454d4ed24842b92a0beae982033 376 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 43 342 29.638 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 SMD11_RS07170 08c40454d4ed24842b92a0beae982033 376 Gene3D G3DSA:1.10.40.50 283 347 1.6E-21 T 06-07-2017 SMD11_RS07170 08c40454d4ed24842b92a0beae982033 376 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 100 335 3.7E-43 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 SMD11_RS07170 08c40454d4ed24842b92a0beae982033 376 Pfam PF03193 Protein of unknown function, DUF258 103 279 8.3E-43 T 06-07-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 SMD11_RS07170 08c40454d4ed24842b92a0beae982033 376 SUPERFAMILY SSF52540 119 340 6.1E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07170 08c40454d4ed24842b92a0beae982033 376 Gene3D G3DSA:3.40.50.300 118 276 5.6E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31360 19ac1e47717a8ce30939803967ae6b7f 71 Gene3D G3DSA:3.40.309.10 1 29 6.1E-4 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS31360 19ac1e47717a8ce30939803967ae6b7f 71 SUPERFAMILY SSF53720 1 55 4.77E-12 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS31360 19ac1e47717a8ce30939803967ae6b7f 71 Pfam PF00171 Aldehyde dehydrogenase family 1 51 1.3E-8 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS16380 b899a4583c0eb1425f91d4e36faaef90 354 Gene3D G3DSA:3.40.47.10 30 171 9.4E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS16380 b899a4583c0eb1425f91d4e36faaef90 354 Gene3D G3DSA:3.40.47.10 172 180 2.6E-8 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS16380 b899a4583c0eb1425f91d4e36faaef90 354 Gene3D G3DSA:3.40.47.10 215 346 2.6E-8 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS16380 b899a4583c0eb1425f91d4e36faaef90 354 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 300 346 2.6E-8 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS16380 b899a4583c0eb1425f91d4e36faaef90 354 SUPERFAMILY SSF53901 3 347 1.42E-21 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS10045 6b8a84a1aff82e1b1d60e38a0cf87fe8 295 SUPERFAMILY SSF89392 163 263 8.24E-7 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX SMD11_RS07930 3a1e8dad3b5b5802bdd1cf20e99a3b0e 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 24 276 2.1E-49 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS07930 3a1e8dad3b5b5802bdd1cf20e99a3b0e 277 Gene3D G3DSA:3.90.226.10 10 217 3.6E-55 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS07930 3a1e8dad3b5b5802bdd1cf20e99a3b0e 277 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 117 137 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMD11_RS07930 3a1e8dad3b5b5802bdd1cf20e99a3b0e 277 SUPERFAMILY SSF52096 11 277 8.6E-75 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS07930 3a1e8dad3b5b5802bdd1cf20e99a3b0e 277 Gene3D G3DSA:1.10.12.10 219 277 1.6E-22 T 06-07-2017 IPR014748 Crontonase, C-terminal SMD11_RS21250 2222fa4e9d5fd1beb45de4ae859c9894 77 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 3 63 8.6E-17 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SMD11_RS21250 2222fa4e9d5fd1beb45de4ae859c9894 77 Pfam PF00367 phosphotransferase system, EIIB 7 39 6.2E-14 T 06-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SMD11_RS21250 2222fa4e9d5fd1beb45de4ae859c9894 77 Gene3D G3DSA:3.30.1360.60 3 77 2.5E-27 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SMD11_RS21250 2222fa4e9d5fd1beb45de4ae859c9894 77 SUPERFAMILY SSF55604 5 76 1.7E-21 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SMD11_RS15630 73ea4a5fe3fff9848dfbd5fac5e335dc 112 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 6 95 7.5E-24 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMD11_RS15630 73ea4a5fe3fff9848dfbd5fac5e335dc 112 Gene3D G3DSA:3.30.1310.10 5 105 1.0E-39 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMD11_RS15630 73ea4a5fe3fff9848dfbd5fac5e335dc 112 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 8 102 21.001 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMD11_RS15630 73ea4a5fe3fff9848dfbd5fac5e335dc 112 PIRSF PIRSF004555 6 112 3.2E-33 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMD11_RS15630 73ea4a5fe3fff9848dfbd5fac5e335dc 112 SUPERFAMILY SSF82607 14 109 8.5E-27 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMD11_RS15630 73ea4a5fe3fff9848dfbd5fac5e335dc 112 Pfam PF02575 YbaB/EbfC DNA-binding family 15 103 3.8E-31 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 SUPERFAMILY SSF54211 244 497 4.17E-91 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 SUPERFAMILY SSF55874 3 216 2.1E-59 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 PRINTS PR00775 90kDa heat shock protein signature 194 212 7.7E-54 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 PRINTS PR00775 90kDa heat shock protein signature 74 91 7.7E-54 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 PRINTS PR00775 90kDa heat shock protein signature 25 47 7.7E-54 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 PRINTS PR00775 90kDa heat shock protein signature 92 109 7.7E-54 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 PRINTS PR00775 90kDa heat shock protein signature 121 143 7.7E-54 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 PRINTS PR00775 90kDa heat shock protein signature 171 188 7.7E-54 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 PRINTS PR00775 90kDa heat shock protein signature 4 24 7.7E-54 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 Hamap MF_00505 Chaperone protein HtpG [htpG]. 1 640 29.957 T 06-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 Gene3D G3DSA:3.30.565.10 4 251 4.8E-74 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 24 33 - T 06-07-2017 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 SUPERFAMILY SSF110942 524 639 2.35E-31 T 06-07-2017 SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 PIRSF PIRSF002583 1 643 2.6E-208 T 06-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 Pfam PF00183 Hsp90 protein 235 640 8.8E-128 T 06-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 SMD11_RS00825 c0cdd5db9e216aaf64d0c284311011ae 643 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 50 156 6.1E-13 T 06-07-2017 SMD11_RS26655 e487e23aa52e66df09d6673ea2bb800e 455 Pfam PF00120 Glutamine synthetase, catalytic domain 121 448 3.7E-103 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS26655 e487e23aa52e66df09d6673ea2bb800e 455 Gene3D G3DSA:3.10.20.70 10 123 3.1E-11 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS26655 e487e23aa52e66df09d6673ea2bb800e 455 Gene3D G3DSA:3.30.590.10 124 442 3.9E-99 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SMD11_RS26655 e487e23aa52e66df09d6673ea2bb800e 455 SMART SM01230 120 373 5.4E-101 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS26655 e487e23aa52e66df09d6673ea2bb800e 455 SUPERFAMILY SSF55931 122 453 2.65E-101 T 06-07-2017 SMD11_RS26655 e487e23aa52e66df09d6673ea2bb800e 455 SUPERFAMILY SSF54368 10 119 5.1E-19 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS13190 8bfe1723a669d62915f65828418a692c 329 SUPERFAMILY SSF56327 157 324 7.87E-62 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMD11_RS13190 8bfe1723a669d62915f65828418a692c 329 PIRSF PIRSF000102 2 326 3.1E-62 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SMD11_RS13190 8bfe1723a669d62915f65828418a692c 329 Gene3D G3DSA:3.40.50.720 5 154 5.3E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS13190 8bfe1723a669d62915f65828418a692c 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 327 57.429 T 06-07-2017 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 SMD11_RS13190 8bfe1723a669d62915f65828418a692c 329 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 156 168 - T 06-07-2017 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMD11_RS13190 8bfe1723a669d62915f65828418a692c 329 SUPERFAMILY SSF51735 4 156 1.15E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS13190 8bfe1723a669d62915f65828418a692c 329 Gene3D G3DSA:3.90.110.10 156 326 3.7E-77 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMD11_RS13190 8bfe1723a669d62915f65828418a692c 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 148 1.1E-31 T 06-07-2017 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 SMD11_RS13190 8bfe1723a669d62915f65828418a692c 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 323 1.8E-148 T 06-07-2017 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 SMD11_RS13190 8bfe1723a669d62915f65828418a692c 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 157 321 3.5E-35 T 06-07-2017 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 SMD11_RS29615 116445cb178e13b71540c10328eace9e 387 SUPERFAMILY SSF47240 131 169 4.37E-5 T 06-07-2017 IPR009078 Ferritin-like superfamily SMD11_RS29615 116445cb178e13b71540c10328eace9e 387 SUPERFAMILY SSF47240 37 99 4.37E-5 T 06-07-2017 IPR009078 Ferritin-like superfamily SMD11_RS29615 116445cb178e13b71540c10328eace9e 387 Pfam PF12902 Ferritin-like 41 258 5.8E-60 T 06-07-2017 SMD11_RS29615 116445cb178e13b71540c10328eace9e 387 Gene3D G3DSA:1.20.1260.10 36 103 5.7E-4 T 06-07-2017 IPR012347 Ferritin-related SMD11_RS07425 061909648afdc4cf05569cd725402605 609 SMART SM00346 350 441 2.0E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS07425 061909648afdc4cf05569cd725402605 609 SMART SM00346 15 105 1.1E-5 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS07425 061909648afdc4cf05569cd725402605 609 SUPERFAMILY SSF46785 351 422 1.88E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07425 061909648afdc4cf05569cd725402605 609 Gene3D G3DSA:1.10.10.10 11 75 2.4E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07425 061909648afdc4cf05569cd725402605 609 Pfam PF09339 IclR helix-turn-helix domain 352 406 5.3E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS07425 061909648afdc4cf05569cd725402605 609 Pfam PF09339 IclR helix-turn-helix domain 18 70 2.6E-9 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS07425 061909648afdc4cf05569cd725402605 609 Gene3D G3DSA:1.10.10.10 350 420 4.1E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07425 061909648afdc4cf05569cd725402605 609 SUPERFAMILY SSF55781 81 227 4.25E-18 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS07425 061909648afdc4cf05569cd725402605 609 Pfam PF01614 Bacterial transcriptional regulator 164 220 9.6E-9 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal SMD11_RS07425 061909648afdc4cf05569cd725402605 609 Pfam PF01614 Bacterial transcriptional regulator 468 595 2.0E-31 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal SMD11_RS07425 061909648afdc4cf05569cd725402605 609 SUPERFAMILY SSF46785 17 87 6.03E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07425 061909648afdc4cf05569cd725402605 609 Gene3D G3DSA:3.30.450.40 83 162 1.8E-13 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS07425 061909648afdc4cf05569cd725402605 609 Gene3D G3DSA:3.30.450.40 164 228 2.4E-17 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS07425 061909648afdc4cf05569cd725402605 609 Gene3D G3DSA:3.30.450.40 421 598 8.8E-52 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS07425 061909648afdc4cf05569cd725402605 609 SUPERFAMILY SSF55781 417 596 3.73E-42 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS24855 208f1f04ae715cd28c4aca18d725d0aa 299 Pfam PF02311 AraC-like ligand binding domain 29 144 2.2E-11 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD11_RS24855 208f1f04ae715cd28c4aca18d725d0aa 299 SMART SM00342 186 269 9.8E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS24855 208f1f04ae715cd28c4aca18d725d0aa 299 SUPERFAMILY SSF51215 6 158 1.44E-20 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD11_RS24855 208f1f04ae715cd28c4aca18d725d0aa 299 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 238 253 7.8E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD11_RS24855 208f1f04ae715cd28c4aca18d725d0aa 299 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 253 269 7.8E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD11_RS24855 208f1f04ae715cd28c4aca18d725d0aa 299 Pfam PF12833 Helix-turn-helix domain 193 271 9.3E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS24855 208f1f04ae715cd28c4aca18d725d0aa 299 Gene3D G3DSA:1.10.10.60 224 272 7.0E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS24855 208f1f04ae715cd28c4aca18d725d0aa 299 Gene3D G3DSA:1.10.10.60 175 223 1.3E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS24855 208f1f04ae715cd28c4aca18d725d0aa 299 SUPERFAMILY SSF46689 222 271 6.72E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS24855 208f1f04ae715cd28c4aca18d725d0aa 299 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 223 265 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD11_RS24855 208f1f04ae715cd28c4aca18d725d0aa 299 Gene3D G3DSA:2.60.120.280 17 158 1.0E-16 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD11_RS08015 3c3ab7f79f13b31b049f2bb3c803a591 221 Gene3D G3DSA:3.40.50.150 7 220 6.0E-77 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS08015 3c3ab7f79f13b31b049f2bb3c803a591 221 Pfam PF01596 O-methyltransferase 17 219 1.1E-65 T 06-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 SMD11_RS08015 3c3ab7f79f13b31b049f2bb3c803a591 221 SUPERFAMILY SSF53335 10 220 1.86E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS23220 1ee394a39f14a663ead23a4dfa14a460 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 30 41 7.3E-5 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS23220 1ee394a39f14a663ead23a4dfa14a460 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 54 7.3E-5 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS23220 1ee394a39f14a663ead23a4dfa14a460 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 65 85 7.3E-5 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS23220 1ee394a39f14a663ead23a4dfa14a460 150 Gene3D G3DSA:1.10.1660.10 29 145 1.0E-31 T 06-07-2017 SMD11_RS23220 1ee394a39f14a663ead23a4dfa14a460 150 SUPERFAMILY SSF46955 29 141 1.4E-29 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS23220 1ee394a39f14a663ead23a4dfa14a460 150 Pfam PF13411 MerR HTH family regulatory protein 29 91 1.0E-15 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS23220 1ee394a39f14a663ead23a4dfa14a460 150 SMART SM00422 29 98 2.4E-17 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS08860 1cffa7012e889dc3279ced3fc54d433b 292 SUPERFAMILY SSF54506 145 282 2.55E-35 T 06-07-2017 SMD11_RS08860 1cffa7012e889dc3279ced3fc54d433b 292 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 5 284 31.353 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMD11_RS08860 1cffa7012e889dc3279ced3fc54d433b 292 SUPERFAMILY SSF54506 5 138 3.14E-33 T 06-07-2017 SMD11_RS08860 1cffa7012e889dc3279ced3fc54d433b 292 Pfam PF01678 Diaminopimelate epimerase 7 136 1.8E-33 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMD11_RS08860 1cffa7012e889dc3279ced3fc54d433b 292 Pfam PF01678 Diaminopimelate epimerase 157 277 7.5E-29 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMD11_RS08860 1cffa7012e889dc3279ced3fc54d433b 292 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 76 90 - T 06-07-2017 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMD11_RS08860 1cffa7012e889dc3279ced3fc54d433b 292 Gene3D G3DSA:3.10.310.10 6 133 1.4E-39 T 06-07-2017 SMD11_RS08860 1cffa7012e889dc3279ced3fc54d433b 292 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 281 1.7E-68 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 SMD11_RS08860 1cffa7012e889dc3279ced3fc54d433b 292 Gene3D G3DSA:3.10.310.10 134 272 5.3E-39 T 06-07-2017 SMD11_RS22860 8f438bc3298e785ed057995519b13038 248 Pfam PF11967 Recombination protein O N terminal 1 85 1.9E-28 T 06-07-2017 IPR022572 DNA replication/recombination mediator RecO, N-terminal SMD11_RS22860 8f438bc3298e785ed057995519b13038 248 Pfam PF02565 Recombination protein O C terminal 91 244 9.9E-34 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SMD11_RS22860 8f438bc3298e785ed057995519b13038 248 Gene3D G3DSA:2.40.50.140 1 87 2.3E-35 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS22860 8f438bc3298e785ed057995519b13038 248 SUPERFAMILY SSF50249 1 83 8.74E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS22860 8f438bc3298e785ed057995519b13038 248 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 242 1.5E-36 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SMD11_RS22860 8f438bc3298e785ed057995519b13038 248 Hamap MF_00201 DNA repair protein RecO [recO]. 2 248 26.114 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SMD11_RS22860 8f438bc3298e785ed057995519b13038 248 SUPERFAMILY SSF57863 89 238 3.66E-39 T 06-07-2017 SMD11_RS12855 b8d4e92e7bb1c58d6d266ba73d999cbc 453 SUPERFAMILY SSF56784 301 449 3.5E-30 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS12855 b8d4e92e7bb1c58d6d266ba73d999cbc 453 Pfam PF02348 Cytidylyltransferase 22 149 4.8E-19 T 06-07-2017 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 SMD11_RS12855 b8d4e92e7bb1c58d6d266ba73d999cbc 453 SUPERFAMILY SSF53448 20 156 1.41E-43 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS12855 b8d4e92e7bb1c58d6d266ba73d999cbc 453 SUPERFAMILY SSF53448 203 284 1.41E-43 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS12855 b8d4e92e7bb1c58d6d266ba73d999cbc 453 Gene3D G3DSA:3.40.50.1000 297 448 5.9E-31 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS12855 b8d4e92e7bb1c58d6d266ba73d999cbc 453 Gene3D G3DSA:3.90.550.10 19 156 3.0E-65 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS12855 b8d4e92e7bb1c58d6d266ba73d999cbc 453 Gene3D G3DSA:3.90.550.10 202 284 3.0E-65 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS12855 b8d4e92e7bb1c58d6d266ba73d999cbc 453 Pfam PF08282 haloacid dehalogenase-like hydrolase 376 435 4.0E-7 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS22045 63521cf4eb8f345e0ac5506af7e0c482 321 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 71 206 5.4E-24 T 06-07-2017 SMD11_RS22045 63521cf4eb8f345e0ac5506af7e0c482 321 SUPERFAMILY SSF53335 6 214 3.51E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS22045 63521cf4eb8f345e0ac5506af7e0c482 321 Gene3D G3DSA:3.40.50.150 12 241 1.3E-65 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS24010 dddfb57daa215b80e087a703a6b82cd8 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 468 3.1E-201 T 06-07-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS24010 dddfb57daa215b80e087a703a6b82cd8 469 SUPERFAMILY SSF54368 6 99 8.89E-29 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS24010 dddfb57daa215b80e087a703a6b82cd8 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 256 271 - T 06-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 SMD11_RS24010 dddfb57daa215b80e087a703a6b82cd8 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 49 67 - T 06-07-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 SMD11_RS24010 dddfb57daa215b80e087a703a6b82cd8 469 Pfam PF00120 Glutamine synthetase, catalytic domain 102 466 1.1E-138 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS24010 dddfb57daa215b80e087a703a6b82cd8 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 385 397 - T 06-07-2017 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS24010 dddfb57daa215b80e087a703a6b82cd8 469 Gene3D G3DSA:3.30.590.10 105 448 1.3E-137 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SMD11_RS24010 dddfb57daa215b80e087a703a6b82cd8 469 Gene3D G3DSA:3.10.20.70 6 104 2.3E-33 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS24010 dddfb57daa215b80e087a703a6b82cd8 469 SMART SM01230 101 378 2.0E-154 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS24010 dddfb57daa215b80e087a703a6b82cd8 469 SUPERFAMILY SSF55931 102 468 3.92E-138 T 06-07-2017 SMD11_RS24010 dddfb57daa215b80e087a703a6b82cd8 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 94 1.6E-22 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS30990 01a96ef2a1f811cb5f5cb00343bd1b5b 985 Pfam PF05729 NACHT domain 147 304 3.9E-12 T 06-07-2017 SMD11_RS30990 01a96ef2a1f811cb5f5cb00343bd1b5b 985 SUPERFAMILY SSF52540 129 308 1.96E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05170 7405cb421538c944625bbc4da2be33c8 292 SUPERFAMILY SSF52402 155 291 1.17E-23 T 06-07-2017 SMD11_RS05170 7405cb421538c944625bbc4da2be33c8 292 Gene3D G3DSA:3.40.50.620 4 138 1.7E-25 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS05170 7405cb421538c944625bbc4da2be33c8 292 Gene3D G3DSA:3.40.50.620 154 290 4.6E-25 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS05170 7405cb421538c944625bbc4da2be33c8 292 PRINTS PR01438 Universal stress protein signature 98 110 3.2E-9 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS05170 7405cb421538c944625bbc4da2be33c8 292 PRINTS PR01438 Universal stress protein signature 3 21 3.2E-9 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS05170 7405cb421538c944625bbc4da2be33c8 292 PRINTS PR01438 Universal stress protein signature 116 138 3.2E-9 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS05170 7405cb421538c944625bbc4da2be33c8 292 SUPERFAMILY SSF52402 5 138 9.21E-21 T 06-07-2017 SMD11_RS05170 7405cb421538c944625bbc4da2be33c8 292 Pfam PF00582 Universal stress protein family 6 138 3.1E-16 T 06-07-2017 IPR006016 UspA GO:0006950 SMD11_RS05170 7405cb421538c944625bbc4da2be33c8 292 Pfam PF00582 Universal stress protein family 155 290 2.3E-17 T 06-07-2017 IPR006016 UspA GO:0006950 SMD11_RS07290 63e790cfcbc921aeed97a6cd08325c3a 805 Gene3D G3DSA:3.30.1590.10 99 227 3.5E-34 T 06-07-2017 SMD11_RS07290 63e790cfcbc921aeed97a6cd08325c3a 805 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 9 804 1.6E-247 T 06-07-2017 IPR012767 Malto-oligosyltrehalose synthase MetaCyc: PWY-2661 SMD11_RS07290 63e790cfcbc921aeed97a6cd08325c3a 805 Pfam PF00128 Alpha amylase, catalytic domain 32 99 2.6E-12 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS07290 63e790cfcbc921aeed97a6cd08325c3a 805 SUPERFAMILY SSF51445 188 715 1.29E-106 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS07290 63e790cfcbc921aeed97a6cd08325c3a 805 SUPERFAMILY SSF51445 10 143 1.29E-106 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS07290 63e790cfcbc921aeed97a6cd08325c3a 805 Gene3D G3DSA:1.10.10.470 544 629 1.9E-16 T 06-07-2017 IPR013797 Maltooligosyl trehalose synthase, N-terminal MetaCyc: PWY-2661 SMD11_RS07290 63e790cfcbc921aeed97a6cd08325c3a 805 SMART SM00642 9 708 3.6E-6 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS07290 63e790cfcbc921aeed97a6cd08325c3a 805 Gene3D G3DSA:3.20.20.80 243 315 7.1E-66 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS07290 63e790cfcbc921aeed97a6cd08325c3a 805 Gene3D G3DSA:3.20.20.80 9 98 7.1E-66 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS07290 63e790cfcbc921aeed97a6cd08325c3a 805 Gene3D G3DSA:3.20.20.80 641 744 7.1E-66 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS07290 63e790cfcbc921aeed97a6cd08325c3a 805 Gene3D G3DSA:3.20.20.80 503 543 7.1E-66 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 Pfam PF00550 Phosphopantetheine attachment site 1433 1497 8.4E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 414 531 9.9E-16 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 Pfam PF08990 Erythronolide synthase docking 2 26 2.3E-8 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 Gene3D G3DSA:3.40.47.10 300 465 9.5E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 SUPERFAMILY SSF51735 1144 1376 1.47E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1457 1472 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 Pfam PF08659 KR domain 1147 1325 7.6E-55 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1147 1327 2.7E-52 T 06-07-2017 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 SMART SM01294 1431 1498 0.0026 T 06-07-2017 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 295 411 2.1E-44 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 200 216 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 Pfam PF00698 Acyl transferase domain 567 886 1.5E-82 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 SUPERFAMILY SSF101173 4 34 5.36E-6 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 SUPERFAMILY SSF55048 692 752 4.32E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 Gene3D G3DSA:3.40.366.10 560 688 1.3E-70 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 Gene3D G3DSA:3.40.366.10 757 869 1.3E-70 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 Gene3D G3DSA:3.30.70.250 691 751 1.6E-6 T 06-07-2017 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 SUPERFAMILY SSF53901 31 155 1.44E-103 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 SUPERFAMILY SSF53901 183 408 1.44E-103 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 SMART SM00823 Phosphopantetheine attachment site 1430 1502 5.4E-26 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 Gene3D G3DSA:1.10.1200.10 1428 1502 5.3E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 Gene3D G3DSA:3.40.47.10 36 299 9.7E-88 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 SMART SM00825 Beta-ketoacyl synthase 36 465 1.1E-211 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 Gene3D G3DSA:3.40.50.720 1148 1362 2.8E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 569 867 4.4E-104 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 SUPERFAMILY SSF52151 759 859 7.85E-66 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 SUPERFAMILY SSF52151 566 694 7.85E-66 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 SUPERFAMILY SSF51735 931 1132 1.22E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 SUPERFAMILY SSF47336 1422 1509 1.57E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08040 3a0a84cc2799e48c7a7c5f8e1978bf75 1550 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 287 2.3E-88 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS13600 36b524542a7d68ac9a8872d930b5ad06 367 SUPERFAMILY SSF48256 3 354 3.79E-96 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS13600 36b524542a7d68ac9a8872d930b5ad06 367 PRINTS PR00143 Citrate synthase signature 182 210 3.4E-26 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS13600 36b524542a7d68ac9a8872d930b5ad06 367 PRINTS PR00143 Citrate synthase signature 294 310 3.4E-26 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS13600 36b524542a7d68ac9a8872d930b5ad06 367 PRINTS PR00143 Citrate synthase signature 160 175 3.4E-26 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS13600 36b524542a7d68ac9a8872d930b5ad06 367 PRINTS PR00143 Citrate synthase signature 314 328 3.4E-26 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS13600 36b524542a7d68ac9a8872d930b5ad06 367 PRINTS PR00143 Citrate synthase signature 235 255 3.4E-26 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS13600 36b524542a7d68ac9a8872d930b5ad06 367 ProSitePatterns PS00480 Citrate synthase signature. 242 254 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SMD11_RS13600 36b524542a7d68ac9a8872d930b5ad06 367 Pfam PF00285 Citrate synthase, C-terminal domain 7 343 3.4E-86 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS13600 36b524542a7d68ac9a8872d930b5ad06 367 Gene3D G3DSA:1.10.580.10 13 221 4.2E-47 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SMD11_RS13600 36b524542a7d68ac9a8872d930b5ad06 367 Gene3D G3DSA:1.10.230.10 222 306 1.3E-25 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 SMD11_RS28145 23e7ef1ed38e3f11cc0d4e252b7e81c6 202 Pfam PF01066 CDP-alcohol phosphatidyltransferase 16 85 8.3E-15 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD11_RS28145 23e7ef1ed38e3f11cc0d4e252b7e81c6 202 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 63 85 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD11_RS28145 23e7ef1ed38e3f11cc0d4e252b7e81c6 202 PIRSF PIRSF000847 11 202 9.5E-43 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 SMD11_RS27485 882292a3eb994204d29d189b38730b86 410 SUPERFAMILY SSF103473 10 389 4.45E-39 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS27485 882292a3eb994204d29d189b38730b86 410 Gene3D G3DSA:1.20.1250.20 216 388 1.4E-9 T 06-07-2017 SMD11_RS27485 882292a3eb994204d29d189b38730b86 410 Gene3D G3DSA:1.20.1250.20 25 205 1.6E-15 T 06-07-2017 SMD11_RS27485 882292a3eb994204d29d189b38730b86 410 Pfam PF07690 Major Facilitator Superfamily 27 353 5.9E-20 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS31890 68e97a0e80425b5ceb41972b8b52d60f 302 SMART SM00342 198 281 4.3E-28 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS31890 68e97a0e80425b5ceb41972b8b52d60f 302 Gene3D G3DSA:2.60.120.10 39 80 1.2E-7 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS31890 68e97a0e80425b5ceb41972b8b52d60f 302 Pfam PF12833 Helix-turn-helix domain 204 282 2.3E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS31890 68e97a0e80425b5ceb41972b8b52d60f 302 Gene3D G3DSA:1.10.10.60 236 283 3.3E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS31890 68e97a0e80425b5ceb41972b8b52d60f 302 SUPERFAMILY SSF51215 27 161 5.89E-9 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD11_RS31890 68e97a0e80425b5ceb41972b8b52d60f 302 SUPERFAMILY SSF46689 234 284 8.96E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS31890 68e97a0e80425b5ceb41972b8b52d60f 302 Pfam PF12852 Cupin 2 164 7.0E-42 T 06-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain SMD11_RS31890 68e97a0e80425b5ceb41972b8b52d60f 302 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 235 277 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD11_RS31890 68e97a0e80425b5ceb41972b8b52d60f 302 SUPERFAMILY SSF46689 182 231 7.17E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS31890 68e97a0e80425b5ceb41972b8b52d60f 302 Gene3D G3DSA:1.10.10.60 180 235 3.4E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS12140 c9bf5f3d95a878d0e85fde2940f8964e 83 Gene3D G3DSA:1.10.287.1040 18 78 2.0E-21 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMD11_RS12140 c9bf5f3d95a878d0e85fde2940f8964e 83 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 19 79 13.711 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMD11_RS12140 c9bf5f3d95a878d0e85fde2940f8964e 83 Pfam PF02609 Exonuclease VII small subunit 20 69 1.7E-17 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMD11_RS12140 c9bf5f3d95a878d0e85fde2940f8964e 83 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 20 74 6.3E-20 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMD11_RS12140 c9bf5f3d95a878d0e85fde2940f8964e 83 SUPERFAMILY SSF116842 18 76 1.7E-15 T 06-07-2017 SMD11_RS12140 c9bf5f3d95a878d0e85fde2940f8964e 83 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 18 58 6.0E-15 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SMD11_RS26460 d34c125a97e873bc45527351bdaff687 532 PIRSF PIRSF002741 1 523 6.0E-71 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD11_RS26460 d34c125a97e873bc45527351bdaff687 532 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 98 449 1.0E-69 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain SMD11_RS26460 d34c125a97e873bc45527351bdaff687 532 Gene3D G3DSA:3.10.105.10 301 500 5.3E-45 T 06-07-2017 SMD11_RS26460 d34c125a97e873bc45527351bdaff687 532 SUPERFAMILY SSF53850 47 516 4.09E-95 T 06-07-2017 SMD11_RS26460 d34c125a97e873bc45527351bdaff687 532 Gene3D G3DSA:3.40.190.10 145 300 1.1E-33 T 06-07-2017 SMD11_RS19275 af292f20b768dffca9c48fb1907c903f 383 Pfam PF06723 MreB/Mbl protein 260 367 9.4E-39 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS19275 af292f20b768dffca9c48fb1907c903f 383 Pfam PF06723 MreB/Mbl protein 10 222 7.8E-103 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS19275 af292f20b768dffca9c48fb1907c903f 383 Gene3D G3DSA:3.30.420.40 158 184 3.7E-35 T 06-07-2017 SMD11_RS19275 af292f20b768dffca9c48fb1907c903f 383 Gene3D G3DSA:3.30.420.40 294 348 3.7E-35 T 06-07-2017 SMD11_RS19275 af292f20b768dffca9c48fb1907c903f 383 Gene3D G3DSA:3.30.420.40 10 157 9.6E-49 T 06-07-2017 SMD11_RS19275 af292f20b768dffca9c48fb1907c903f 383 SUPERFAMILY SSF53067 262 358 8.87E-43 T 06-07-2017 SMD11_RS19275 af292f20b768dffca9c48fb1907c903f 383 SUPERFAMILY SSF53067 147 230 8.87E-43 T 06-07-2017 SMD11_RS19275 af292f20b768dffca9c48fb1907c903f 383 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 185 205 1.2E-42 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS19275 af292f20b768dffca9c48fb1907c903f 383 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 130 149 1.2E-42 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS19275 af292f20b768dffca9c48fb1907c903f 383 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 67 90 1.2E-42 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS19275 af292f20b768dffca9c48fb1907c903f 383 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 47 65 1.2E-42 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS19275 af292f20b768dffca9c48fb1907c903f 383 Gene3D G3DSA:3.90.640.10 257 290 8.0E-31 T 06-07-2017 SMD11_RS19275 af292f20b768dffca9c48fb1907c903f 383 Gene3D G3DSA:3.90.640.10 185 225 8.0E-31 T 06-07-2017 SMD11_RS19275 af292f20b768dffca9c48fb1907c903f 383 SUPERFAMILY SSF53067 10 146 3.89E-43 T 06-07-2017 SMD11_RS00985 4bf0e5f65c05accf0274b719398fa4e3 141 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 90 3.0E-8 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD11_RS00985 4bf0e5f65c05accf0274b719398fa4e3 141 Gene3D G3DSA:2.30.110.10 6 137 1.3E-22 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS00985 4bf0e5f65c05accf0274b719398fa4e3 141 SUPERFAMILY SSF50475 3 139 3.93E-23 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS00445 ffb4c9522e4e355535a3e21497597ad0 166 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 49 86 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SMD11_RS00445 ffb4c9522e4e355535a3e21497597ad0 166 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 97 6.0E-18 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 SMD11_RS00445 ffb4c9522e4e355535a3e21497597ad0 166 Gene3D G3DSA:3.40.140.10 3 141 2.8E-35 T 06-07-2017 SMD11_RS00445 ffb4c9522e4e355535a3e21497597ad0 166 SUPERFAMILY SSF53927 3 119 9.03E-35 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 SMD11_RS10070 40badcdec31ba052b504ce62a33273f8 621 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 458 477 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 SMD11_RS10070 40badcdec31ba052b504ce62a33273f8 621 Gene3D G3DSA:3.40.50.1220 217 381 1.5E-66 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS10070 40badcdec31ba052b504ce62a33273f8 621 SUPERFAMILY SSF52518 398 609 1.45E-68 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS10070 40badcdec31ba052b504ce62a33273f8 621 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 222 357 4.8E-47 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMD11_RS10070 40badcdec31ba052b504ce62a33273f8 621 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 33 607 4.7E-229 T 06-07-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 SMD11_RS10070 40badcdec31ba052b504ce62a33273f8 621 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 421 583 5.8E-49 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMD11_RS10070 40badcdec31ba052b504ce62a33273f8 621 SUPERFAMILY SSF52467 214 389 1.33E-61 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS10070 40badcdec31ba052b504ce62a33273f8 621 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 33 198 3.2E-54 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMD11_RS10070 40badcdec31ba052b504ce62a33273f8 621 Gene3D G3DSA:3.40.50.970 31 208 1.1E-69 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS10070 40badcdec31ba052b504ce62a33273f8 621 SUPERFAMILY SSF52518 31 211 1.43E-58 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS10070 40badcdec31ba052b504ce62a33273f8 621 Gene3D G3DSA:3.40.50.970 382 599 3.3E-77 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS01645 c16d0b1e5aeb664dd112ef02043cade2 481 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 130 289 1.7E-39 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS01645 c16d0b1e5aeb664dd112ef02043cade2 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 283 301 1.6E-18 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS01645 c16d0b1e5aeb664dd112ef02043cade2 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 310 326 1.6E-18 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS01645 c16d0b1e5aeb664dd112ef02043cade2 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 366 383 1.6E-18 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS01645 c16d0b1e5aeb664dd112ef02043cade2 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 247 260 1.6E-18 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS01645 c16d0b1e5aeb664dd112ef02043cade2 481 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 294 451 3.7E-42 T 06-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS01645 c16d0b1e5aeb664dd112ef02043cade2 481 SMART SM00846 129 289 9.5E-52 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS01645 c16d0b1e5aeb664dd112ef02043cade2 481 SUPERFAMILY SSF55347 289 452 5.66E-48 T 06-07-2017 SMD11_RS01645 c16d0b1e5aeb664dd112ef02043cade2 481 SUPERFAMILY SSF51735 130 305 6.44E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS01645 c16d0b1e5aeb664dd112ef02043cade2 481 Gene3D G3DSA:3.40.50.720 130 297 2.0E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS01645 c16d0b1e5aeb664dd112ef02043cade2 481 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 287 294 - T 06-07-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS01645 c16d0b1e5aeb664dd112ef02043cade2 481 Gene3D G3DSA:3.30.360.10 298 453 9.8E-49 T 06-07-2017 SMD11_RS01645 c16d0b1e5aeb664dd112ef02043cade2 481 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 131 463 1.4E-110 T 06-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS10085 b5efc03b2dfba6caae97311d96b5ee42 330 Pfam PF00248 Aldo/keto reductase family 16 320 2.7E-60 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS10085 b5efc03b2dfba6caae97311d96b5ee42 330 Gene3D G3DSA:3.20.20.100 2 322 2.4E-111 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS10085 b5efc03b2dfba6caae97311d96b5ee42 330 SUPERFAMILY SSF51430 2 322 4.71E-89 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 Gene3D G3DSA:3.30.230.10 454 562 2.3E-25 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 137 2.5E-25 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 Gene3D G3DSA:3.30.70.240 563 632 4.2E-6 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 Gene3D G3DSA:3.40.50.300 179 251 2.1E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 Gene3D G3DSA:3.40.50.300 3 159 3.3E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 Gene3D G3DSA:2.40.30.10 274 361 1.9E-6 T 06-07-2017 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 SUPERFAMILY SSF54980 371 443 2.09E-8 T 06-07-2017 IPR009022 Elongation factor G, III-V domain SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 SUPERFAMILY SSF54211 449 561 6.45E-15 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 SUPERFAMILY SSF54980 564 637 1.82E-6 T 06-07-2017 IPR009022 Elongation factor G, III-V domain SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 Pfam PF03764 Elongation factor G, domain IV 455 560 2.1E-18 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 Pfam PF00009 Elongation factor Tu GTP binding domain 5 250 4.3E-51 T 06-07-2017 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 SMART SM00889 445 561 1.0E-12 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 SUPERFAMILY SSF50447 235 363 3.04E-8 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 112 135 5.2E-25 T 06-07-2017 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 533 550 5.2E-25 T 06-07-2017 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 224 246 5.2E-25 T 06-07-2017 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 499 521 5.2E-25 T 06-07-2017 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 484 498 5.2E-25 T 06-07-2017 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 PRINTS PR00315 GTP-binding elongation factor signature 8 21 5.6E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 PRINTS PR00315 GTP-binding elongation factor signature 126 135 5.6E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 PRINTS PR00315 GTP-binding elongation factor signature 54 62 5.6E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 PRINTS PR00315 GTP-binding elongation factor signature 74 84 5.6E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 PRINTS PR00315 GTP-binding elongation factor signature 90 101 5.6E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 Pfam PF00679 Elongation factor G C-terminus 564 636 1.5E-7 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 Gene3D G3DSA:3.30.70.870 373 442 1.0E-8 T 06-07-2017 SMD11_RS07115 18d4a2dbc24e54286f8d34a7273f2c5d 670 SUPERFAMILY SSF52540 2 250 9.33E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 SMART SM00825 Beta-ketoacyl synthase 12 436 1.5E-175 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 265 383 5.5E-35 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 Gene3D G3DSA:1.10.1200.10 1290 1345 2.9E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 SUPERFAMILY SSF55048 670 732 1.57E-8 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 SMART SM00823 Phosphopantetheine attachment site 1290 1345 2.2E-9 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 Pfam PF00698 Acyl transferase domain 544 825 1.1E-85 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 10 257 6.4E-86 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 Pfam PF00550 Phosphopantetheine attachment site 1292 1355 1.1E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 SUPERFAMILY SSF52151 733 833 3.66E-70 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 SUPERFAMILY SSF52151 543 670 3.66E-70 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 393 506 2.2E-11 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 546 841 1.1E-104 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 170 186 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 Gene3D G3DSA:3.40.47.10 12 268 1.6E-87 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 Gene3D G3DSA:3.40.47.10 271 435 2.6E-48 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 SUPERFAMILY SSF53901 8 382 3.68E-90 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 Pfam PF14765 Polyketide synthase dehydratase 922 1165 2.9E-20 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 SUPERFAMILY SSF47336 1285 1357 2.62E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 Gene3D G3DSA:3.40.366.10 541 664 3.6E-73 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS20415 99fa5ac56f0097ffb1603492b71137b5 1358 Gene3D G3DSA:3.40.366.10 731 843 3.6E-73 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS06285 eccbfe16fcc20cfdc547079f8244ab0c 181 Pfam PF01965 DJ-1/PfpI family 2 172 1.3E-48 T 06-07-2017 IPR002818 DJ-1/PfpI SMD11_RS06285 eccbfe16fcc20cfdc547079f8244ab0c 181 SUPERFAMILY SSF52317 1 175 3.01E-40 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS06285 eccbfe16fcc20cfdc547079f8244ab0c 181 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 6 174 1.6E-45 T 06-07-2017 IPR006286 Peptidase C56, PfpI SMD11_RS06285 eccbfe16fcc20cfdc547079f8244ab0c 181 Gene3D G3DSA:3.40.50.880 1 175 2.7E-48 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS20670 19b06cfe3557ceb3b90bdc7a88653b5b 458 Pfam PF01996 F420-0:Gamma-glutamyl ligase 102 224 1.1E-33 T 06-07-2017 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 SMD11_RS20670 19b06cfe3557ceb3b90bdc7a88653b5b 458 Pfam PF01996 F420-0:Gamma-glutamyl ligase 28 89 4.4E-10 T 06-07-2017 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 SMD11_RS20670 19b06cfe3557ceb3b90bdc7a88653b5b 458 SUPERFAMILY SSF144010 22 261 1.27E-66 T 06-07-2017 SMD11_RS20670 19b06cfe3557ceb3b90bdc7a88653b5b 458 SUPERFAMILY SSF55469 263 457 4.06E-36 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS20670 19b06cfe3557ceb3b90bdc7a88653b5b 458 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 21 256 1.2E-74 T 06-07-2017 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 SMD11_RS20670 19b06cfe3557ceb3b90bdc7a88653b5b 458 Gene3D G3DSA:3.40.109.10 260 455 2.1E-36 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS20670 19b06cfe3557ceb3b90bdc7a88653b5b 458 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 25 458 51.732 T 06-07-2017 IPR023661 Coenzyme F420:L-glutamate ligase, bacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 SMD11_RS20670 19b06cfe3557ceb3b90bdc7a88653b5b 458 Gene3D G3DSA:3.30.1330.100 139 229 6.6E-57 T 06-07-2017 SMD11_RS20670 19b06cfe3557ceb3b90bdc7a88653b5b 458 Gene3D G3DSA:3.30.1330.100 21 72 6.6E-57 T 06-07-2017 SMD11_RS20670 19b06cfe3557ceb3b90bdc7a88653b5b 458 Gene3D G3DSA:3.90.1660.10 73 138 5.6E-23 T 06-07-2017 SMD11_RS20670 19b06cfe3557ceb3b90bdc7a88653b5b 458 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 265 457 2.9E-95 T 06-07-2017 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 SMD11_RS20670 19b06cfe3557ceb3b90bdc7a88653b5b 458 Pfam PF00881 Nitroreductase family 270 438 1.8E-25 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMD11_RS22230 0fb9a5cf2fd46695f6ca22473a9d11e3 465 Pfam PF00324 Amino acid permease 26 432 9.4E-110 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMD11_RS22230 0fb9a5cf2fd46695f6ca22473a9d11e3 465 PIRSF PIRSF006060 8 458 1.3E-73 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS22230 0fb9a5cf2fd46695f6ca22473a9d11e3 465 ProSitePatterns PS00218 Amino acid permeases signature. 51 81 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD11_RS21565 f3b447f0c0bbcd74a0d220125eaa673a 576 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 135 6.7E-9 T 06-07-2017 IPR000014 PAS domain SMD11_RS21565 f3b447f0c0bbcd74a0d220125eaa673a 576 SMART SM00052 313 564 5.3E-106 T 06-07-2017 IPR001633 EAL domain SMD11_RS21565 f3b447f0c0bbcd74a0d220125eaa673a 576 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 136 301 1.2E-33 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS21565 f3b447f0c0bbcd74a0d220125eaa673a 576 Gene3D G3DSA:3.20.20.450 317 569 1.6E-104 T 06-07-2017 IPR001633 EAL domain SMD11_RS21565 f3b447f0c0bbcd74a0d220125eaa673a 576 Pfam PF08448 PAS fold 22 129 3.8E-6 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS21565 f3b447f0c0bbcd74a0d220125eaa673a 576 Pfam PF00990 Diguanylate cyclase, GGDEF domain 140 298 1.6E-40 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS21565 f3b447f0c0bbcd74a0d220125eaa673a 576 Gene3D G3DSA:3.30.70.270 140 308 9.4E-51 T 06-07-2017 SMD11_RS21565 f3b447f0c0bbcd74a0d220125eaa673a 576 SMART SM00267 128 303 3.4E-51 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS21565 f3b447f0c0bbcd74a0d220125eaa673a 576 Gene3D G3DSA:3.30.450.20 12 128 2.1E-13 T 06-07-2017 SMD11_RS21565 f3b447f0c0bbcd74a0d220125eaa673a 576 Pfam PF00563 EAL domain 320 559 1.9E-67 T 06-07-2017 IPR001633 EAL domain SMD11_RS21565 f3b447f0c0bbcd74a0d220125eaa673a 576 SUPERFAMILY SSF55785 13 116 5.9E-11 T 06-07-2017 IPR000014 PAS domain SMD11_RS21565 f3b447f0c0bbcd74a0d220125eaa673a 576 SUPERFAMILY SSF55073 145 305 1.49E-40 T 06-07-2017 IPR029787 Nucleotide cyclase SMD11_RS21565 f3b447f0c0bbcd74a0d220125eaa673a 576 SUPERFAMILY SSF141868 320 569 5.36E-83 T 06-07-2017 IPR001633 EAL domain SMD11_RS28855 bed395e4294c695b1f075628c8276e62 130 Pfam PF00720 Subtilisin inhibitor-like 35 116 6.2E-23 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 SMD11_RS28855 bed395e4294c695b1f075628c8276e62 130 SUPERFAMILY SSF55399 39 130 3.79E-24 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 SMD11_RS28855 bed395e4294c695b1f075628c8276e62 130 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 54 81 2.2E-9 T 06-07-2017 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD11_RS28855 bed395e4294c695b1f075628c8276e62 130 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 105 121 2.2E-9 T 06-07-2017 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD11_RS28855 bed395e4294c695b1f075628c8276e62 130 Gene3D G3DSA:3.30.350.10 33 130 1.1E-32 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 SMD11_RS28855 bed395e4294c695b1f075628c8276e62 130 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 35 118 4.0E-7 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 SMD11_RS08240 18eb8ffcd3b75f53331f8845e87a08c7 86 ProSitePatterns PS00012 Phosphopantetheine attachment site. 31 46 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS08240 18eb8ffcd3b75f53331f8845e87a08c7 86 Gene3D G3DSA:1.10.1200.10 8 77 6.9E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08240 18eb8ffcd3b75f53331f8845e87a08c7 86 SUPERFAMILY SSF47336 5 80 3.01E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08240 18eb8ffcd3b75f53331f8845e87a08c7 86 Pfam PF00550 Phosphopantetheine attachment site 8 70 1.4E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS27555 7f261ec9fa38fdf5419213038582b431 476 Pfam PF13529 Peptidase_C39 like family 263 414 8.4E-28 T 06-07-2017 SMD11_RS10805 b53c50dadd92e2571effdb59ca046c94 187 Pfam PF00430 ATP synthase B/B' CF(0) 23 152 3.2E-27 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SMD11_RS10805 b53c50dadd92e2571effdb59ca046c94 187 Hamap MF_01398 ATP synthase subunit b [atpF]. 4 173 11.862 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SMD11_RS10805 b53c50dadd92e2571effdb59ca046c94 187 SUPERFAMILY SSF81573 79 137 9.02E-11 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMD11_RS10805 b53c50dadd92e2571effdb59ca046c94 187 Gene3D G3DSA:1.20.5.620 79 138 1.8E-11 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMD11_RS10805 b53c50dadd92e2571effdb59ca046c94 187 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 27 173 4.7E-25 T 06-07-2017 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 SMD11_RS06970 46a8d6b02b38ca5cfb051982453082cb 154 Pfam PF12840 Helix-turn-helix domain 51 103 9.7E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06970 46a8d6b02b38ca5cfb051982453082cb 154 SUPERFAMILY SSF46785 39 129 1.93E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06970 46a8d6b02b38ca5cfb051982453082cb 154 Gene3D G3DSA:1.10.10.10 50 129 4.8E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06970 46a8d6b02b38ca5cfb051982453082cb 154 SMART SM00418 51 128 7.0E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS06970 46a8d6b02b38ca5cfb051982453082cb 154 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 1.9E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS06970 46a8d6b02b38ca5cfb051982453082cb 154 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 1.9E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS04835 4a9f5b3f008f2df703e34996624cdeb8 306 Gene3D G3DSA:2.120.10.30 51 281 2.6E-16 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS04835 4a9f5b3f008f2df703e34996624cdeb8 306 SUPERFAMILY SSF63829 51 303 4.32E-20 T 06-07-2017 SMD11_RS05485 7a7a3ac007886c466923be752dd3c9e5 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 8.9E-33 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS05485 7a7a3ac007886c466923be752dd3c9e5 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD11_RS05485 7a7a3ac007886c466923be752dd3c9e5 380 Gene3D G3DSA:2.40.110.10 123 218 5.5E-41 T 06-07-2017 SMD11_RS05485 7a7a3ac007886c466923be752dd3c9e5 380 SUPERFAMILY SSF56645 4 242 4.19E-82 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS05485 7a7a3ac007886c466923be752dd3c9e5 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 379 2.7E-41 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS05485 7a7a3ac007886c466923be752dd3c9e5 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD11_RS05485 7a7a3ac007886c466923be752dd3c9e5 380 Gene3D G3DSA:1.20.140.10 219 379 7.3E-57 T 06-07-2017 SMD11_RS05485 7a7a3ac007886c466923be752dd3c9e5 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 2.2E-26 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS05485 7a7a3ac007886c466923be752dd3c9e5 380 Gene3D G3DSA:1.10.540.10 5 120 1.3E-33 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS05485 7a7a3ac007886c466923be752dd3c9e5 380 SUPERFAMILY SSF47203 228 379 3.89E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS16800 affbf49effa76a49f6b26ef0d05afb31 876 Pfam PF00912 Transglycosylase 168 338 1.9E-51 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 SMD11_RS16800 affbf49effa76a49f6b26ef0d05afb31 876 SUPERFAMILY SSF56601 325 347 1.83E-79 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS16800 affbf49effa76a49f6b26ef0d05afb31 876 SUPERFAMILY SSF56601 379 773 1.83E-79 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS16800 affbf49effa76a49f6b26ef0d05afb31 876 Gene3D G3DSA:1.10.3810.10 166 345 4.0E-58 T 06-07-2017 SMD11_RS16800 affbf49effa76a49f6b26ef0d05afb31 876 Gene3D G3DSA:3.40.710.10 346 783 1.6E-97 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS16800 affbf49effa76a49f6b26ef0d05afb31 876 Pfam PF00905 Penicillin binding protein transpeptidase domain 537 711 7.4E-23 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD11_RS16800 affbf49effa76a49f6b26ef0d05afb31 876 SUPERFAMILY SSF53955 152 366 5.06E-60 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS28285 fe60d6eebd34631b55808641e4ef85f8 228 Pfam PF03167 Uracil DNA glycosylase superfamily 57 208 6.3E-24 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS28285 fe60d6eebd34631b55808641e4ef85f8 228 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 9 214 2.1E-78 T 06-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS28285 fe60d6eebd34631b55808641e4ef85f8 228 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 8 222 39.883 T 06-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS28285 fe60d6eebd34631b55808641e4ef85f8 228 SUPERFAMILY SSF52141 6 222 3.18E-88 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS28285 fe60d6eebd34631b55808641e4ef85f8 228 SMART SM00987 52 211 6.1E-33 T 06-07-2017 SMD11_RS28285 fe60d6eebd34631b55808641e4ef85f8 228 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 60 69 - T 06-07-2017 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS28285 fe60d6eebd34631b55808641e4ef85f8 228 SMART SM00986 52 211 6.1E-33 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS28285 fe60d6eebd34631b55808641e4ef85f8 228 Gene3D G3DSA:3.40.470.10 4 223 1.1E-92 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 SUPERFAMILY SSF53933 1370 1425 8.5E-6 T 06-07-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1239 1305 2.3E-17 T 06-07-2017 IPR022385 Rhs repeat-associated core GO:0097264 SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 Gene3D G3DSA:3.10.450.30 1368 1425 7.9E-6 T 06-07-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 612 638 6.5E-4 T 06-07-2017 IPR006530 YD repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 780 819 1.2E-8 T 06-07-2017 IPR006530 YD repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 633 673 5.3E-11 T 06-07-2017 IPR006530 YD repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 719 756 1.6E-6 T 06-07-2017 IPR006530 YD repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 823 863 7.9E-5 T 06-07-2017 IPR006530 YD repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 577 607 1.7E-6 T 06-07-2017 IPR006530 YD repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 675 713 2.9E-6 T 06-07-2017 IPR006530 YD repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 885 924 9.9E-5 T 06-07-2017 IPR006530 YD repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 463 500 9.2E-9 T 06-07-2017 IPR006530 YD repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1094 1125 1.4E-7 T 06-07-2017 IPR006530 YD repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1013 1041 1.6E-4 T 06-07-2017 IPR006530 YD repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 527 568 6.8E-5 T 06-07-2017 IPR006530 YD repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 925 953 6.9E-4 T 06-07-2017 IPR006530 YD repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 Pfam PF05593 RHS Repeat 484 514 5.9E-5 T 06-07-2017 IPR031325 RHS repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 Pfam PF05593 RHS Repeat 885 920 7.9E-7 T 06-07-2017 IPR031325 RHS repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 Pfam PF05593 RHS Repeat 617 648 7.0E-7 T 06-07-2017 IPR031325 RHS repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 Pfam PF05593 RHS Repeat 781 817 1.0E-10 T 06-07-2017 IPR031325 RHS repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 Pfam PF05593 RHS Repeat 1013 1045 3.1E-5 T 06-07-2017 IPR031325 RHS repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 Pfam PF05593 RHS Repeat 1094 1122 2.8E-7 T 06-07-2017 IPR031325 RHS repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 Pfam PF05593 RHS Repeat 637 669 1.2E-6 T 06-07-2017 IPR031325 RHS repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 Pfam PF05593 RHS Repeat 569 607 1.1E-8 T 06-07-2017 IPR031325 RHS repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 Pfam PF05593 RHS Repeat 676 712 9.7E-5 T 06-07-2017 IPR031325 RHS repeat SMD11_RS22650 447bb0091c22873b345fa7eb05298ba3 1429 Pfam PF05593 RHS Repeat 925 959 6.3E-5 T 06-07-2017 IPR031325 RHS repeat SMD11_RS11080 5136baa99e926d088d7b6fd6d728e42b 320 SMART SM00829 13 318 3.0E-12 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS11080 5136baa99e926d088d7b6fd6d728e42b 320 SUPERFAMILY SSF51735 126 287 5.55E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS11080 5136baa99e926d088d7b6fd6d728e42b 320 Gene3D G3DSA:3.40.50.720 159 267 4.6E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS11080 5136baa99e926d088d7b6fd6d728e42b 320 Gene3D G3DSA:3.90.180.10 11 158 1.8E-28 T 06-07-2017 IPR011032 GroES-like SMD11_RS11080 5136baa99e926d088d7b6fd6d728e42b 320 Pfam PF00107 Zinc-binding dehydrogenase 165 283 8.8E-18 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS11080 5136baa99e926d088d7b6fd6d728e42b 320 SUPERFAMILY SSF50129 6 154 3.58E-29 T 06-07-2017 IPR011032 GroES-like SMD11_RS10355 a61d77134a1ecbf509fb819af2551f7d 622 SMART SM00382 404 583 1.5E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS10355 a61d77134a1ecbf509fb819af2551f7d 622 Gene3D G3DSA:3.40.50.300 375 608 1.5E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10355 a61d77134a1ecbf509fb819af2551f7d 622 SUPERFAMILY SSF90123 22 336 7.32E-71 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS10355 a61d77134a1ecbf509fb819af2551f7d 622 Gene3D G3DSA:1.20.1560.10 22 334 4.2E-68 T 06-07-2017 SMD11_RS10355 a61d77134a1ecbf509fb819af2551f7d 622 Pfam PF00664 ABC transporter transmembrane region 35 305 9.9E-41 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS10355 a61d77134a1ecbf509fb819af2551f7d 622 ProSitePatterns PS00211 ABC transporters family signature. 515 529 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS10355 a61d77134a1ecbf509fb819af2551f7d 622 Pfam PF00005 ABC transporter 395 542 1.0E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS10355 a61d77134a1ecbf509fb819af2551f7d 622 SUPERFAMILY SSF52540 373 610 1.16E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14705 5bcc63332fae2d3afb68e433344b3382 274 Gene3D G3DSA:3.20.20.150 7 265 6.2E-49 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS14705 5bcc63332fae2d3afb68e433344b3382 274 SUPERFAMILY SSF51658 8 266 6.81E-46 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS14705 5bcc63332fae2d3afb68e433344b3382 274 Pfam PF01261 Xylose isomerase-like TIM barrel 29 215 1.3E-18 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS31815 9ef10d8dce4fa08fc7ba5426c6e86bac 780 Gene3D G3DSA:3.40.50.300 220 451 1.5E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31815 9ef10d8dce4fa08fc7ba5426c6e86bac 780 SMART SM00240 29 79 4.5E-10 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS31815 9ef10d8dce4fa08fc7ba5426c6e86bac 780 SMART SM00240 139 190 5.0E-14 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS31815 9ef10d8dce4fa08fc7ba5426c6e86bac 780 Pfam PF00498 FHA domain 140 204 1.4E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS31815 9ef10d8dce4fa08fc7ba5426c6e86bac 780 Pfam PF00005 ABC transporter 243 390 6.6E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS31815 9ef10d8dce4fa08fc7ba5426c6e86bac 780 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 26 94 1.2E-14 T 06-07-2017 IPR032030 YscD, cytoplasmic domain SMD11_RS31815 9ef10d8dce4fa08fc7ba5426c6e86bac 780 Pfam PF01061 ABC-2 type transporter 516 723 2.5E-20 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD11_RS31815 9ef10d8dce4fa08fc7ba5426c6e86bac 780 SUPERFAMILY SSF49879 106 230 1.63E-26 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 SMD11_RS31815 9ef10d8dce4fa08fc7ba5426c6e86bac 780 ProSitePatterns PS00211 ABC transporters family signature. 362 376 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS31815 9ef10d8dce4fa08fc7ba5426c6e86bac 780 SUPERFAMILY SSF52540 219 457 7.83E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31815 9ef10d8dce4fa08fc7ba5426c6e86bac 780 SUPERFAMILY SSF49879 21 95 2.87E-19 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 SMD11_RS31815 9ef10d8dce4fa08fc7ba5426c6e86bac 780 Gene3D G3DSA:2.60.200.20 129 211 3.2E-23 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS31815 9ef10d8dce4fa08fc7ba5426c6e86bac 780 Gene3D G3DSA:2.60.200.20 8 94 7.9E-19 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS31815 9ef10d8dce4fa08fc7ba5426c6e86bac 780 SMART SM00382 252 446 8.0E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 Gene3D G3DSA:2.40.30.10 923 1020 4.0E-30 T 06-07-2017 SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 SUPERFAMILY SSF50447 922 1020 3.95E-25 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 426 1020 2.8E-227 T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 516 675 3.0E-29 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 1020 16.619 T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 ProSitePatterns PS01176 Initiation factor 2 signature. 973 995 - T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 SUPERFAMILY SSF50447 692 775 1.27E-24 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 Gene3D G3DSA:3.40.50.10050 820 900 3.0E-23 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 50 5.6E-12 T 06-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 435 480 8.2E-7 T 06-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 PRINTS PR00315 GTP-binding elongation factor signature 518 531 1.1E-9 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 PRINTS PR00315 GTP-binding elongation factor signature 622 631 1.1E-9 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 PRINTS PR00315 GTP-binding elongation factor signature 586 597 1.1E-9 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 PRINTS PR00315 GTP-binding elongation factor signature 570 580 1.1E-9 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 Gene3D G3DSA:2.40.30.10 690 784 8.7E-23 T 06-07-2017 SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 Gene3D G3DSA:3.40.50.300 514 679 2.6E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 SUPERFAMILY SSF52156 799 928 5.49E-36 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 Pfam PF00009 Elongation factor Tu GTP binding domain 519 679 8.8E-33 T 06-07-2017 SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 Pfam PF11987 Translation-initiation factor 2 810 911 5.8E-34 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 SMD11_RS09240 ab79623399ea63d595226f96bb64f242 1021 SUPERFAMILY SSF52540 510 681 7.02E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20030 5c0b7ff11b1424b80dce256fecd6daaa 396 Gene3D G3DSA:3.40.710.10 255 394 1.8E-72 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS20030 5c0b7ff11b1424b80dce256fecd6daaa 396 Gene3D G3DSA:3.40.710.10 7 221 1.8E-72 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS20030 5c0b7ff11b1424b80dce256fecd6daaa 396 SUPERFAMILY SSF56601 9 390 1.04E-62 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS20030 5c0b7ff11b1424b80dce256fecd6daaa 396 Pfam PF00144 Beta-lactamase 17 386 7.8E-66 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS05065 14034b72a6890ac72906ae0d9ad3a937 392 Pfam PF17179 4Fe-4S dicluster domain 273 367 5.7E-32 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD11_RS05065 14034b72a6890ac72906ae0d9ad3a937 392 Gene3D G3DSA:1.10.1060.10 267 387 7.8E-11 T 06-07-2017 SMD11_RS05065 14034b72a6890ac72906ae0d9ad3a937 392 SUPERFAMILY SSF46548 269 382 2.62E-15 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 SMD11_RS05065 14034b72a6890ac72906ae0d9ad3a937 392 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 274 285 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD11_RS05065 14034b72a6890ac72906ae0d9ad3a937 392 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 353 364 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD11_RS22790 129dadc6e7bc53b453d1b69c940ad7a0 116 SUPERFAMILY SSF53927 12 111 3.2E-10 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 SMD11_RS22790 129dadc6e7bc53b453d1b69c940ad7a0 116 Gene3D G3DSA:3.40.140.10 17 109 7.6E-7 T 06-07-2017 SMD11_RS29770 f5df8254b665454441a65358e94a7da4 584 SUPERFAMILY SSF51246 328 445 1.26E-37 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS29770 f5df8254b665454441a65358e94a7da4 584 SMART SM00878 333 441 5.5E-57 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS29770 f5df8254b665454441a65358e94a7da4 584 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 320 3.0E-75 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS29770 f5df8254b665454441a65358e94a7da4 584 Gene3D G3DSA:3.30.1490.20 129 201 5.0E-21 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS29770 f5df8254b665454441a65358e94a7da4 584 SUPERFAMILY SSF56059 114 321 6.89E-59 T 06-07-2017 SMD11_RS29770 f5df8254b665454441a65358e94a7da4 584 Gene3D G3DSA:3.30.470.20 203 445 1.3E-90 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS29770 f5df8254b665454441a65358e94a7da4 584 SUPERFAMILY SSF51230 510 582 5.1E-20 T 06-07-2017 IPR011053 Single hybrid motif SMD11_RS29770 f5df8254b665454441a65358e94a7da4 584 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 539 556 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS29770 f5df8254b665454441a65358e94a7da4 584 Gene3D G3DSA:3.40.50.20 2 128 1.4E-50 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS29770 f5df8254b665454441a65358e94a7da4 584 Pfam PF00364 Biotin-requiring enzyme 517 582 3.7E-17 T 06-07-2017 IPR000089 Biotin/lipoyl attachment SMD11_RS29770 f5df8254b665454441a65358e94a7da4 584 SUPERFAMILY SSF52440 2 112 7.12E-47 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS29770 f5df8254b665454441a65358e94a7da4 584 Gene3D G3DSA:2.40.50.100 512 583 1.6E-22 T 06-07-2017 SMD11_RS29770 f5df8254b665454441a65358e94a7da4 584 Pfam PF02785 Biotin carboxylase C-terminal domain 333 441 3.7E-36 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS29770 f5df8254b665454441a65358e94a7da4 584 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS29770 f5df8254b665454441a65358e94a7da4 584 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 2.2E-44 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS12635 f5df8254b665454441a65358e94a7da4 584 SUPERFAMILY SSF51246 328 445 1.26E-37 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS12635 f5df8254b665454441a65358e94a7da4 584 SMART SM00878 333 441 5.5E-57 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS12635 f5df8254b665454441a65358e94a7da4 584 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 320 3.0E-75 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS12635 f5df8254b665454441a65358e94a7da4 584 Gene3D G3DSA:3.30.1490.20 129 201 5.0E-21 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS12635 f5df8254b665454441a65358e94a7da4 584 SUPERFAMILY SSF56059 114 321 6.89E-59 T 06-07-2017 SMD11_RS12635 f5df8254b665454441a65358e94a7da4 584 Gene3D G3DSA:3.30.470.20 203 445 1.3E-90 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS12635 f5df8254b665454441a65358e94a7da4 584 SUPERFAMILY SSF51230 510 582 5.1E-20 T 06-07-2017 IPR011053 Single hybrid motif SMD11_RS12635 f5df8254b665454441a65358e94a7da4 584 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 539 556 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS12635 f5df8254b665454441a65358e94a7da4 584 Gene3D G3DSA:3.40.50.20 2 128 1.4E-50 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS12635 f5df8254b665454441a65358e94a7da4 584 Pfam PF00364 Biotin-requiring enzyme 517 582 3.7E-17 T 06-07-2017 IPR000089 Biotin/lipoyl attachment SMD11_RS12635 f5df8254b665454441a65358e94a7da4 584 SUPERFAMILY SSF52440 2 112 7.12E-47 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS12635 f5df8254b665454441a65358e94a7da4 584 Gene3D G3DSA:2.40.50.100 512 583 1.6E-22 T 06-07-2017 SMD11_RS12635 f5df8254b665454441a65358e94a7da4 584 Pfam PF02785 Biotin carboxylase C-terminal domain 333 441 3.7E-36 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS12635 f5df8254b665454441a65358e94a7da4 584 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS12635 f5df8254b665454441a65358e94a7da4 584 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 2.2E-44 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS32355 7812d50ca9c6a981a8aac088d2f3400d 63 Pfam PF13459 4Fe-4S single cluster domain 3 60 1.1E-12 T 06-07-2017 SMD11_RS32355 7812d50ca9c6a981a8aac088d2f3400d 63 Gene3D G3DSA:3.30.70.20 1 62 1.7E-15 T 06-07-2017 SMD11_RS32355 7812d50ca9c6a981a8aac088d2f3400d 63 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 6.9E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD11_RS32355 7812d50ca9c6a981a8aac088d2f3400d 63 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 6.9E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD11_RS32355 7812d50ca9c6a981a8aac088d2f3400d 63 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 6.9E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD11_RS32355 7812d50ca9c6a981a8aac088d2f3400d 63 SUPERFAMILY SSF54862 2 62 3.64E-13 T 06-07-2017 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 181 199 1.2E-29 T 06-07-2017 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 322 1.2E-29 T 06-07-2017 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 285 1.2E-29 T 06-07-2017 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.2E-29 T 06-07-2017 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 1.2E-29 T 06-07-2017 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 PIRSF PIRSF000350 1 468 2.6E-75 T 06-07-2017 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 43 53 - T 06-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 Gene3D G3DSA:3.50.50.60 154 343 1.1E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 Gene3D G3DSA:3.50.50.60 9 153 1.6E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 SUPERFAMILY SSF55424 353 474 1.19E-34 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 9 474 1.8E-127 T 06-07-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 337 5.7E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 357 463 8.1E-31 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 Gene3D G3DSA:3.30.390.30 344 471 1.4E-38 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 SUPERFAMILY SSF51905 9 387 1.84E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 3.2E-67 T 06-07-2017 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 3.2E-67 T 06-07-2017 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 284 3.2E-67 T 06-07-2017 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 181 206 3.2E-67 T 06-07-2017 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 154 3.2E-67 T 06-07-2017 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 353 374 3.2E-67 T 06-07-2017 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 439 459 3.2E-67 T 06-07-2017 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 315 322 3.2E-67 T 06-07-2017 SMD11_RS07300 b056c7a5fd31314cb45cb308618b89a0 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 432 3.2E-67 T 06-07-2017 SMD11_RS05390 7c4926622a3b6b4c4f4bb99382e001b6 315 Gene3D G3DSA:1.20.1510.10 28 221 7.5E-58 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain SMD11_RS05390 7c4926622a3b6b4c4f4bb99382e001b6 315 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 29 304 5.9E-90 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMD11_RS05390 7c4926622a3b6b4c4f4bb99382e001b6 315 SUPERFAMILY SSF160240 224 303 2.22E-12 T 06-07-2017 SMD11_RS05390 7c4926622a3b6b4c4f4bb99382e001b6 315 Pfam PF01545 Cation efflux family 30 221 2.3E-47 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SMD11_RS05390 7c4926622a3b6b4c4f4bb99382e001b6 315 Gene3D G3DSA:3.30.70.1350 228 303 1.5E-4 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain SMD11_RS05390 7c4926622a3b6b4c4f4bb99382e001b6 315 SUPERFAMILY SSF161111 27 222 1.15E-53 T 06-07-2017 SMD11_RS26185 028d902a0906699b17d9a77d6154bae6 249 Gene3D G3DSA:1.10.10.10 12 83 5.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26185 028d902a0906699b17d9a77d6154bae6 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 2.2E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS26185 028d902a0906699b17d9a77d6154bae6 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 2.2E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS26185 028d902a0906699b17d9a77d6154bae6 249 SUPERFAMILY SSF64288 68 247 7.22E-35 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS26185 028d902a0906699b17d9a77d6154bae6 249 SMART SM00345 21 80 1.5E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS26185 028d902a0906699b17d9a77d6154bae6 249 Pfam PF07702 UTRA domain 107 240 8.1E-26 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS26185 028d902a0906699b17d9a77d6154bae6 249 SUPERFAMILY SSF46785 12 89 1.19E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26185 028d902a0906699b17d9a77d6154bae6 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 80 8.2E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS26185 028d902a0906699b17d9a77d6154bae6 249 SMART SM00866 101 241 3.3E-20 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS26185 028d902a0906699b17d9a77d6154bae6 249 Gene3D G3DSA:3.40.1410.10 92 245 5.2E-33 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS21825 540f0364bfd8413391e05f88d39eb66c 735 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 8 731 6.1E-201 T 06-07-2017 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 SMD11_RS21825 540f0364bfd8413391e05f88d39eb66c 735 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 4 735 29.158 T 06-07-2017 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 SMD11_RS21825 540f0364bfd8413391e05f88d39eb66c 735 Pfam PF13604 AAA domain 336 514 2.3E-45 T 06-07-2017 SMD11_RS21825 540f0364bfd8413391e05f88d39eb66c 735 Pfam PF14520 Helix-hairpin-helix domain 94 138 1.6E-6 T 06-07-2017 SMD11_RS21825 540f0364bfd8413391e05f88d39eb66c 735 Pfam PF13538 UvrD-like helicase C-terminal domain 658 706 1.4E-19 T 06-07-2017 IPR027785 UvrD-like helicase C-terminal domain SMD11_RS21825 540f0364bfd8413391e05f88d39eb66c 735 SUPERFAMILY SSF47781 85 162 1.11E-9 T 06-07-2017 IPR010994 RuvA domain 2-like SMD11_RS21825 540f0364bfd8413391e05f88d39eb66c 735 Gene3D G3DSA:3.40.50.300 308 511 1.2E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21825 540f0364bfd8413391e05f88d39eb66c 735 Gene3D G3DSA:3.40.50.300 651 710 1.3E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21825 540f0364bfd8413391e05f88d39eb66c 735 SUPERFAMILY SSF52540 184 255 1.87E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21825 540f0364bfd8413391e05f88d39eb66c 735 SUPERFAMILY SSF52540 332 483 1.87E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21825 540f0364bfd8413391e05f88d39eb66c 735 Pfam PF14490 Helix-hairpin-helix containing domain 144 234 6.0E-30 T 06-07-2017 IPR029493 RecD helicase-like helix-hairpin-helix domain SMD11_RS21825 540f0364bfd8413391e05f88d39eb66c 735 SMART SM00382 349 551 0.0086 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS21825 540f0364bfd8413391e05f88d39eb66c 735 SUPERFAMILY SSF52540 553 719 2.16E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21825 540f0364bfd8413391e05f88d39eb66c 735 SUPERFAMILY SSF52540 445 512 2.16E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02955 8299b9f7f72cb1cd4e4cff20ef772c8f 280 SMART SM01236 121 224 3.1E-16 T 06-07-2017 SMD11_RS02955 8299b9f7f72cb1cd4e4cff20ef772c8f 280 Pfam PF14518 Iron-containing redox enzyme 90 256 2.5E-26 T 06-07-2017 IPR028201 PqqC-like protein SMD11_RS02955 8299b9f7f72cb1cd4e4cff20ef772c8f 280 SUPERFAMILY SSF48613 70 262 1.3E-13 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS02955 8299b9f7f72cb1cd4e4cff20ef772c8f 280 Gene3D G3DSA:1.20.910.10 54 237 1.1E-27 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS04390 da83f1417551796477184d4e659968f4 272 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 258 1.5E-26 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS04390 da83f1417551796477184d4e659968f4 272 Gene3D G3DSA:1.10.601.10 33 109 2.4E-16 T 06-07-2017 SMD11_RS04390 da83f1417551796477184d4e659968f4 272 Pfam PF04542 Sigma-70 region 2 42 110 1.5E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS04390 da83f1417551796477184d4e659968f4 272 Gene3D G3DSA:1.10.10.10 200 258 3.4E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04390 da83f1417551796477184d4e659968f4 272 Pfam PF04545 Sigma-70, region 4 207 256 2.5E-16 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS04390 da83f1417551796477184d4e659968f4 272 PRINTS PR00046 Major sigma-70 factor signature 228 243 4.5E-6 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS04390 da83f1417551796477184d4e659968f4 272 PRINTS PR00046 Major sigma-70 factor signature 211 223 4.5E-6 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS04390 da83f1417551796477184d4e659968f4 272 PRINTS PR00046 Major sigma-70 factor signature 65 78 4.5E-6 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS04390 da83f1417551796477184d4e659968f4 272 SUPERFAMILY SSF88946 18 110 5.97E-23 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS04390 da83f1417551796477184d4e659968f4 272 Gene3D G3DSA:1.10.10.10 110 163 9.0E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04390 da83f1417551796477184d4e659968f4 272 SUPERFAMILY SSF88659 190 258 2.62E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Gene3D G3DSA:3.40.50.1820 2094 2212 1.1E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Gene3D G3DSA:3.40.50.1820 2295 2372 1.1E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Pfam PF00668 Condensation domain 1053 1352 8.1E-39 T 06-07-2017 IPR001242 Condensation domain SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Pfam PF00668 Condensation domain 1 280 4.6E-28 T 06-07-2017 IPR001242 Condensation domain SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 SMART SM00823 Phosphopantetheine attachment site 2021 2090 3.8E-5 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 SMART SM00823 Phosphopantetheine attachment site 959 1027 0.0037 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 SUPERFAMILY SSF52777 1242 1481 9.23E-39 T 06-07-2017 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Gene3D G3DSA:3.40.50.980 442 596 3.5E-49 T 06-07-2017 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Gene3D G3DSA:3.40.50.980 1498 1654 1.6E-38 T 06-07-2017 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 SUPERFAMILY SSF47336 954 1021 3.93E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Gene3D G3DSA:3.30.300.30 1902 2027 1.0E-26 T 06-07-2017 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Gene3D G3DSA:3.30.300.30 848 965 3.2E-36 T 06-07-2017 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Gene3D G3DSA:1.10.1200.10 2028 2088 8.8E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Gene3D G3DSA:1.10.1200.10 966 1025 1.2E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Pfam PF00975 Thioesterase domain 2108 2370 5.0E-37 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Gene3D G3DSA:2.30.38.10 1819 1895 1.6E-20 T 06-07-2017 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Gene3D G3DSA:2.30.38.10 765 842 5.5E-30 T 06-07-2017 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 ProSitePatterns PS00455 Putative AMP-binding domain signature. 588 599 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 SMART SM00824 Thioesterase 2113 2373 1.0E-4 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 SUPERFAMILY SSF52777 1 168 9.56E-30 T 06-07-2017 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Gene3D G3DSA:3.40.50.980 1655 1818 6.7E-29 T 06-07-2017 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Gene3D G3DSA:3.40.50.980 597 764 7.8E-46 T 06-07-2017 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 SUPERFAMILY SSF56801 1496 2034 1.7E-125 T 06-07-2017 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 SUPERFAMILY SSF53474 2088 2373 1.39E-64 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 ProSitePatterns PS00012 Phosphopantetheine attachment site. 983 998 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1645 1656 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 SUPERFAMILY SSF56801 409 972 2.35E-156 T 06-07-2017 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 SUPERFAMILY SSF52777 179 409 3.67E-30 T 06-07-2017 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 SUPERFAMILY SSF52777 1052 1254 1.89E-28 T 06-07-2017 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 SUPERFAMILY SSF47336 2016 2086 3.14E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Pfam PF00501 AMP-binding enzyme 1503 1906 6.2E-77 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Pfam PF00501 AMP-binding enzyme 449 852 1.3E-104 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 471 876 1.0E-135 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1524 1920 1.2E-105 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Pfam PF00550 Phosphopantetheine attachment site 961 1022 2.3E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Pfam PF00550 Phosphopantetheine attachment site 2023 2086 1.6E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Pfam PF13193 AMP-binding enzyme C-terminal domain 1924 1992 7.9E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS30170 fb36a495379195a0b178d2906ff4146d 2384 Pfam PF13193 AMP-binding enzyme C-terminal domain 860 933 6.1E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS16985 2a46e0695eb24e9250c1dcd12b822803 175 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 56 73 - T 06-07-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 SMD11_RS16985 2a46e0695eb24e9250c1dcd12b822803 175 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 171 5.2E-45 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD11_RS16985 2a46e0695eb24e9250c1dcd12b822803 175 Gene3D G3DSA:2.40.100.10 4 172 5.0E-62 T 06-07-2017 IPR029000 Cyclophilin-like domain SMD11_RS16985 2a46e0695eb24e9250c1dcd12b822803 175 PIRSF PIRSF001467 1 175 3.7E-55 T 06-07-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 SMD11_RS16985 2a46e0695eb24e9250c1dcd12b822803 175 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 20 35 5.6E-28 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD11_RS16985 2a46e0695eb24e9250c1dcd12b822803 175 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 61 73 5.6E-28 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD11_RS16985 2a46e0695eb24e9250c1dcd12b822803 175 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 101 116 5.6E-28 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD11_RS16985 2a46e0695eb24e9250c1dcd12b822803 175 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 116 128 5.6E-28 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD11_RS16985 2a46e0695eb24e9250c1dcd12b822803 175 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 129 144 5.6E-28 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SMD11_RS16985 2a46e0695eb24e9250c1dcd12b822803 175 SUPERFAMILY SSF50891 6 171 1.13E-60 T 06-07-2017 IPR029000 Cyclophilin-like domain SMD11_RS14385 7b0e28ceaeb2bab267d6d11ca53d7109 577 SUPERFAMILY SSF90123 6 314 3.53E-73 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS14385 7b0e28ceaeb2bab267d6d11ca53d7109 577 SMART SM00382 360 572 2.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS14385 7b0e28ceaeb2bab267d6d11ca53d7109 577 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS14385 7b0e28ceaeb2bab267d6d11ca53d7109 577 Pfam PF00664 ABC transporter transmembrane region 18 288 5.0E-44 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS14385 7b0e28ceaeb2bab267d6d11ca53d7109 577 Gene3D G3DSA:3.40.50.300 333 564 1.0E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14385 7b0e28ceaeb2bab267d6d11ca53d7109 577 Pfam PF00005 ABC transporter 351 498 9.2E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS14385 7b0e28ceaeb2bab267d6d11ca53d7109 577 Gene3D G3DSA:1.20.1560.10 7 315 7.4E-67 T 06-07-2017 SMD11_RS14385 7b0e28ceaeb2bab267d6d11ca53d7109 577 SUPERFAMILY SSF52540 325 570 7.32E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15300 f8f580cb6839674f914c340439b292d1 113 Pfam PF01740 STAS domain 8 108 6.3E-19 T 06-07-2017 IPR002645 STAS domain SMD11_RS15300 f8f580cb6839674f914c340439b292d1 113 SUPERFAMILY SSF52091 3 110 9.03E-32 T 06-07-2017 IPR002645 STAS domain SMD11_RS15300 f8f580cb6839674f914c340439b292d1 113 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 3 106 2.5E-33 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMD11_RS15300 f8f580cb6839674f914c340439b292d1 113 Gene3D G3DSA:3.30.750.24 4 111 1.6E-40 T 06-07-2017 IPR002645 STAS domain SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 ProSitePatterns PS00455 Putative AMP-binding domain signature. 618 629 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 SUPERFAMILY SSF56801 456 964 3.53E-135 T 06-07-2017 SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 Pfam PF13193 AMP-binding enzyme C-terminal domain 874 948 4.4E-8 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 Pfam PF13745 HxxPF-repeated domain 333 424 6.4E-11 T 06-07-2017 SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 Pfam PF00550 Phosphopantetheine attachment site 991 1054 1.1E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 SMART SM00823 Phosphopantetheine attachment site 989 1058 5.1E-8 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 Gene3D G3DSA:3.40.50.980 473 639 1.6E-39 T 06-07-2017 SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 Gene3D G3DSA:2.30.38.10 781 855 1.7E-22 T 06-07-2017 SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 Gene3D G3DSA:1.10.1200.10 993 1056 6.2E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 SUPERFAMILY SSF47336 983 1054 1.7E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 SUPERFAMILY SSF52777 199 442 5.45E-40 T 06-07-2017 SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 SUPERFAMILY SSF52777 18 212 9.78E-26 T 06-07-2017 SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 Pfam PF00501 AMP-binding enzyme 478 866 5.8E-92 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 498 890 2.8E-110 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 Gene3D G3DSA:3.30.300.30 862 992 3.0E-24 T 06-07-2017 SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 Gene3D G3DSA:3.40.50.980 640 780 4.2E-36 T 06-07-2017 SMD11_RS08280 613a0d4655c03868f99d07d25a30ffa3 1063 Pfam PF00668 Condensation domain 24 311 8.8E-34 T 06-07-2017 IPR001242 Condensation domain SMD11_RS07945 bf463370e20d1a3b845c2fbfa39957f0 915 SUPERFAMILY SSF56091 537 628 5.22E-10 T 06-07-2017 SMD11_RS07945 bf463370e20d1a3b845c2fbfa39957f0 915 SUPERFAMILY SSF56091 731 821 5.22E-10 T 06-07-2017 SMD11_RS07945 bf463370e20d1a3b845c2fbfa39957f0 915 SUPERFAMILY SSF52540 29 170 1.25E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07945 bf463370e20d1a3b845c2fbfa39957f0 915 Pfam PF16542 PNKP adenylyltransferase domain, ligase domain 488 695 3.9E-95 T 06-07-2017 IPR032380 Polynucleotide kinase-phosphatase, ligase domain SMD11_RS07945 bf463370e20d1a3b845c2fbfa39957f0 915 Pfam PF16542 PNKP adenylyltransferase domain, ligase domain 727 852 3.4E-41 T 06-07-2017 IPR032380 Polynucleotide kinase-phosphatase, ligase domain SMD11_RS07945 bf463370e20d1a3b845c2fbfa39957f0 915 Pfam PF13671 AAA domain 29 157 8.0E-23 T 06-07-2017 SMD11_RS07945 bf463370e20d1a3b845c2fbfa39957f0 915 TIGRFAM TIGR04075 bacter_Pnkp: polynucleotide kinase-phosphatase 22 694 0.0 T 06-07-2017 IPR024028 Polynucleotide kinase-phosphatase, bacterial SMD11_RS07945 bf463370e20d1a3b845c2fbfa39957f0 915 Pfam PF16536 PNKP adenylyltransferase domain, C-terminal region 857 915 1.5E-32 T 06-07-2017 IPR032390 Polynucleotide kinase-phosphatase, C-terminal SMD11_RS07945 bf463370e20d1a3b845c2fbfa39957f0 915 SUPERFAMILY SSF56300 140 423 1.39E-43 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS07945 bf463370e20d1a3b845c2fbfa39957f0 915 Gene3D G3DSA:3.60.21.10 197 445 8.4E-52 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS07945 bf463370e20d1a3b845c2fbfa39957f0 915 Gene3D G3DSA:3.40.50.300 29 157 8.2E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07945 bf463370e20d1a3b845c2fbfa39957f0 915 Pfam PF00149 Calcineurin-like phosphoesterase 201 402 3.7E-12 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 SMD11_RS09635 eb447e1648c1ae85883a0fa97ffb128f 115 SMART SM00938 4 108 6.5E-53 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMD11_RS09635 eb447e1648c1ae85883a0fa97ffb128f 115 Pfam PF00543 Nitrogen regulatory protein P-II 4 108 2.3E-35 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMD11_RS09635 eb447e1648c1ae85883a0fa97ffb128f 115 Gene3D G3DSA:3.30.70.120 1 115 2.9E-42 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SMD11_RS09635 eb447e1648c1ae85883a0fa97ffb128f 115 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 06-07-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 SMD11_RS09635 eb447e1648c1ae85883a0fa97ffb128f 115 PRINTS PR00340 P-II protein signature 23 41 1.5E-23 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMD11_RS09635 eb447e1648c1ae85883a0fa97ffb128f 115 PRINTS PR00340 P-II protein signature 2 17 1.5E-23 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMD11_RS09635 eb447e1648c1ae85883a0fa97ffb128f 115 PRINTS PR00340 P-II protein signature 86 106 1.5E-23 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 SMD11_RS09635 eb447e1648c1ae85883a0fa97ffb128f 115 SUPERFAMILY SSF54913 1 115 1.11E-38 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta SMD11_RS01670 ee48563cc3fcfbaebe24cfa63a04c991 369 Gene3D G3DSA:3.50.50.60 2 175 3.8E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01670 ee48563cc3fcfbaebe24cfa63a04c991 369 Gene3D G3DSA:3.50.50.60 269 347 3.8E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01670 ee48563cc3fcfbaebe24cfa63a04c991 369 SUPERFAMILY SSF51905 3 169 4.02E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01670 ee48563cc3fcfbaebe24cfa63a04c991 369 SUPERFAMILY SSF51905 268 348 4.02E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01670 ee48563cc3fcfbaebe24cfa63a04c991 369 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 8.1E-15 T 06-07-2017 SMD11_RS01670 ee48563cc3fcfbaebe24cfa63a04c991 369 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 8.1E-15 T 06-07-2017 SMD11_RS01670 ee48563cc3fcfbaebe24cfa63a04c991 369 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 8.1E-15 T 06-07-2017 SMD11_RS01670 ee48563cc3fcfbaebe24cfa63a04c991 369 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 8.1E-15 T 06-07-2017 SMD11_RS01670 ee48563cc3fcfbaebe24cfa63a04c991 369 Pfam PF01494 FAD binding domain 3 339 9.1E-25 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 101 351 7.1E-90 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1862 2112 4.9E-91 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Pfam PF00550 Phosphopantetheine attachment site 16 77 9.4E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Pfam PF00550 Phosphopantetheine attachment site 1771 1837 1.3E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Pfam PF00550 Phosphopantetheine attachment site 3485 3551 4.3E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SUPERFAMILY SSF52151 2538 2640 2.07E-74 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SUPERFAMILY SSF52151 2369 2483 2.07E-74 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Gene3D G3DSA:1.10.1200.10 3480 3556 1.0E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Gene3D G3DSA:1.10.1200.10 1766 1841 4.5E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Gene3D G3DSA:3.40.50.720 1477 1660 3.1E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SUPERFAMILY SSF53901 98 473 8.3E-101 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SUPERFAMILY SSF52151 684 816 7.06E-71 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SUPERFAMILY SSF52151 873 968 7.06E-71 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SUPERFAMILY SSF55048 2488 2545 1.7E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Gene3D G3DSA:3.30.70.250 2487 2543 1.7E-7 T 06-07-2017 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Gene3D G3DSA:3.30.70.250 814 864 2.1E-6 T 06-07-2017 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SMART SM00826 2720 2878 4.7E-82 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SMART SM00826 1052 1217 8.5E-80 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SMART SM00823 Phosphopantetheine attachment site 1769 1841 1.1E-30 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SMART SM00823 Phosphopantetheine attachment site 3483 3555 1.7E-31 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SMART SM00823 Phosphopantetheine attachment site 7 81 9.5E-24 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SUPERFAMILY SSF51735 3197 3409 4.74E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3510 3525 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Pfam PF00698 Acyl transferase domain 2372 2671 1.7E-52 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Pfam PF00698 Acyl transferase domain 688 1000 1.2E-52 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SUPERFAMILY SSF51735 1324 1465 5.12E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SUPERFAMILY SSF47336 1763 1877 3.01E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2025 2041 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SUPERFAMILY SSF47336 3475 3560 3.53E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Gene3D G3DSA:3.40.47.10 364 530 5.7E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Gene3D G3DSA:3.40.47.10 2125 2291 8.4E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Pfam PF14765 Polyketide synthase dehydratase 2720 2985 5.6E-54 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Pfam PF14765 Polyketide synthase dehydratase 1052 1317 1.7E-50 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Gene3D G3DSA:1.10.1200.10 20 105 7.6E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SUPERFAMILY SSF51735 1476 1694 1.15E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Gene3D G3DSA:3.40.50.720 3197 3396 2.4E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1478 1658 7.3E-62 T 06-07-2017 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3199 3376 1.7E-56 T 06-07-2017 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SUPERFAMILY SSF53901 1859 2234 4.83E-101 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SUPERFAMILY SSF47336 4 115 1.7E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SUPERFAMILY SSF51735 2990 3184 3.11E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SUPERFAMILY SSF55048 815 872 8.5E-9 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SMART SM01294 1770 1837 3.2E-6 T 06-07-2017 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SMART SM01294 16 77 2.6E-5 T 06-07-2017 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SMART SM01294 3484 3551 8.2E-4 T 06-07-2017 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Gene3D G3DSA:3.40.47.10 1860 2124 2.8E-89 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Gene3D G3DSA:3.40.47.10 106 363 1.0E-89 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SMART SM00825 Beta-ketoacyl synthase 103 530 1.3E-219 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SMART SM00825 Beta-ketoacyl synthase 1864 2291 5.9E-226 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Pfam PF08659 KR domain 3199 3374 8.3E-56 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Pfam PF08659 KR domain 1478 1657 9.8E-56 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Gene3D G3DSA:3.40.366.10 2367 2483 2.1E-77 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Gene3D G3DSA:3.40.366.10 2544 2654 2.1E-77 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Gene3D G3DSA:3.40.366.10 680 810 5.8E-77 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Gene3D G3DSA:3.40.366.10 871 983 5.8E-77 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2120 2237 1.2E-42 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 359 476 2.3E-41 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2372 2652 1.1E-121 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 688 981 2.6E-121 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1796 1811 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 479 535 5.1E-8 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08220 0168997f5564602d0fcf39042f56d8c8 3637 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2240 2355 8.7E-13 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS13045 3bb748246c60d3ce9dddccab9b704e84 697 Gene3D G3DSA:3.40.50.2000 200 362 8.5E-19 T 06-07-2017 SMD11_RS13045 3bb748246c60d3ce9dddccab9b704e84 697 Pfam PF00534 Glycosyl transferases group 1 199 362 6.7E-33 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 SMD11_RS13045 3bb748246c60d3ce9dddccab9b704e84 697 SUPERFAMILY SSF53756 91 383 9.14E-63 T 06-07-2017 SMD11_RS13045 3bb748246c60d3ce9dddccab9b704e84 697 SUPERFAMILY SSF53756 2 59 9.14E-63 T 06-07-2017 SMD11_RS29650 6b3e242a6e04a4eca37272965ac29081 504 PRINTS PR00733 Glycosyl hydrolase family 6 signature 343 353 1.6E-30 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS29650 6b3e242a6e04a4eca37272965ac29081 504 PRINTS PR00733 Glycosyl hydrolase family 6 signature 227 240 1.6E-30 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS29650 6b3e242a6e04a4eca37272965ac29081 504 PRINTS PR00733 Glycosyl hydrolase family 6 signature 312 325 1.6E-30 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS29650 6b3e242a6e04a4eca37272965ac29081 504 PRINTS PR00733 Glycosyl hydrolase family 6 signature 187 206 1.6E-30 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS29650 6b3e242a6e04a4eca37272965ac29081 504 PRINTS PR00733 Glycosyl hydrolase family 6 signature 455 469 1.6E-30 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS29650 6b3e242a6e04a4eca37272965ac29081 504 PRINTS PR00733 Glycosyl hydrolase family 6 signature 431 451 1.6E-30 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS29650 6b3e242a6e04a4eca37272965ac29081 504 PRINTS PR00733 Glycosyl hydrolase family 6 signature 255 270 1.6E-30 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS29650 6b3e242a6e04a4eca37272965ac29081 504 SUPERFAMILY SSF51989 159 387 1.15E-79 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS29650 6b3e242a6e04a4eca37272965ac29081 504 SUPERFAMILY SSF51989 428 490 1.15E-79 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS29650 6b3e242a6e04a4eca37272965ac29081 504 Gene3D G3DSA:3.20.20.40 432 490 1.0E-90 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS29650 6b3e242a6e04a4eca37272965ac29081 504 Gene3D G3DSA:3.20.20.40 165 394 1.0E-90 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS29650 6b3e242a6e04a4eca37272965ac29081 504 Pfam PF01341 Glycosyl hydrolases family 6 183 475 5.2E-78 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 SMD11_RS29650 6b3e242a6e04a4eca37272965ac29081 504 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 232 248 - T 06-07-2017 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 SMD11_RS22315 f573a8ba907df17829e45e22377c1c5e 425 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 410 1.1E-197 T 06-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 SMD11_RS22315 f573a8ba907df17829e45e22377c1c5e 425 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 316 393 2.7E-15 T 06-07-2017 IPR019489 Clp ATPase, C-terminal SMD11_RS22315 f573a8ba907df17829e45e22377c1c5e 425 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 414 52.503 T 06-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 SMD11_RS22315 f573a8ba907df17829e45e22377c1c5e 425 Pfam PF06689 ClpX C4-type zinc finger 11 48 8.9E-21 T 06-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 SMD11_RS22315 f573a8ba907df17829e45e22377c1c5e 425 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 310 2.0E-51 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS22315 f573a8ba907df17829e45e22377c1c5e 425 SUPERFAMILY SSF52540 58 401 1.35E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22315 f573a8ba907df17829e45e22377c1c5e 425 SMART SM01086 316 410 5.8E-31 T 06-07-2017 IPR019489 Clp ATPase, C-terminal SMD11_RS22315 f573a8ba907df17829e45e22377c1c5e 425 SUPERFAMILY SSF57716 11 46 1.35E-11 T 06-07-2017 SMD11_RS22315 f573a8ba907df17829e45e22377c1c5e 425 Gene3D G3DSA:1.10.8.60 315 411 9.2E-35 T 06-07-2017 SMD11_RS22315 f573a8ba907df17829e45e22377c1c5e 425 SMART SM00382 112 332 3.0E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS22315 f573a8ba907df17829e45e22377c1c5e 425 SMART SM00994 10 49 1.1E-23 T 06-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 SMD11_RS22315 f573a8ba907df17829e45e22377c1c5e 425 Gene3D G3DSA:3.40.50.300 293 310 4.8E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22315 f573a8ba907df17829e45e22377c1c5e 425 Gene3D G3DSA:3.40.50.300 62 254 4.8E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28740 fa31d77004457040bdfbc8c338495d16 257 Gene3D G3DSA:3.40.50.1110 10 193 1.3E-34 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS28740 fa31d77004457040bdfbc8c338495d16 257 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 12 183 2.2E-22 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS28740 fa31d77004457040bdfbc8c338495d16 257 SUPERFAMILY SSF52266 9 192 1.33E-36 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS00870 f1966bd430fa4178e309206c2f76f362 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 6.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00870 f1966bd430fa4178e309206c2f76f362 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 6.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00870 f1966bd430fa4178e309206c2f76f362 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 6.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00870 f1966bd430fa4178e309206c2f76f362 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00870 f1966bd430fa4178e309206c2f76f362 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 6.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00870 f1966bd430fa4178e309206c2f76f362 289 SUPERFAMILY SSF51735 4 238 3.22E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00870 f1966bd430fa4178e309206c2f76f362 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 6.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00870 f1966bd430fa4178e309206c2f76f362 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 6.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00870 f1966bd430fa4178e309206c2f76f362 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 6.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00870 f1966bd430fa4178e309206c2f76f362 289 Pfam PF00106 short chain dehydrogenase 9 191 5.4E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00870 f1966bd430fa4178e309206c2f76f362 289 Gene3D G3DSA:3.40.50.720 6 238 1.4E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00870 f1966bd430fa4178e309206c2f76f362 289 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 192 0.0043 T 06-07-2017 SMD11_RS31605 8ea03f418c2cb20c6b1ce489d0ab0bc0 758 SUPERFAMILY SSF48576 3 332 1.18E-66 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS31605 8ea03f418c2cb20c6b1ce489d0ab0bc0 758 Gene3D G3DSA:1.10.600.10 378 718 8.9E-94 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS31605 8ea03f418c2cb20c6b1ce489d0ab0bc0 758 Gene3D G3DSA:1.10.600.10 3 328 1.1E-104 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS31605 8ea03f418c2cb20c6b1ce489d0ab0bc0 758 SUPERFAMILY SSF48576 384 723 1.09E-64 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS03580 a4d262f4fc1b3fe3a4db20c5b3386ed6 616 Gene3D G3DSA:1.20.1560.10 35 327 2.3E-35 T 06-07-2017 SMD11_RS03580 a4d262f4fc1b3fe3a4db20c5b3386ed6 616 Pfam PF00005 ABC transporter 430 508 4.9E-11 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS03580 a4d262f4fc1b3fe3a4db20c5b3386ed6 616 Pfam PF00664 ABC transporter transmembrane region 41 302 1.8E-24 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS03580 a4d262f4fc1b3fe3a4db20c5b3386ed6 616 Gene3D G3DSA:3.40.50.300 393 575 2.8E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03580 a4d262f4fc1b3fe3a4db20c5b3386ed6 616 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS03580 a4d262f4fc1b3fe3a4db20c5b3386ed6 616 SUPERFAMILY SSF90123 20 328 3.14E-44 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS03580 a4d262f4fc1b3fe3a4db20c5b3386ed6 616 SUPERFAMILY SSF52540 394 575 1.91E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23685 642d3accff98c8ddf1e5f2658c33f391 376 Pfam PF09375 Imelysin 139 370 1.6E-41 T 06-07-2017 SMD11_RS23685 642d3accff98c8ddf1e5f2658c33f391 376 Pfam PF13473 Cupredoxin-like domain 16 123 6.7E-14 T 06-07-2017 IPR028096 EfeO-type cupredoxin-like domain SMD11_RS23685 642d3accff98c8ddf1e5f2658c33f391 376 Gene3D G3DSA:2.60.40.420 57 148 6.1E-4 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS19815 d0345e9b790f3b6a998e7e7c061969d6 157 SUPERFAMILY SSF81330 17 137 5.62E-26 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMD11_RS19815 d0345e9b790f3b6a998e7e7c061969d6 157 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 11 144 3.7E-22 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMD11_RS19815 d0345e9b790f3b6a998e7e7c061969d6 157 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 9 141 9.8E-35 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMD11_RS19815 d0345e9b790f3b6a998e7e7c061969d6 157 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 18 31 - T 06-07-2017 IPR019823 Large-conductance mechanosensitive channel, conserved site SMD11_RS09645 8ce59e817de102c7a7efda4be3435db2 473 Gene3D G3DSA:1.25.40.10 215 425 2.8E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS09645 8ce59e817de102c7a7efda4be3435db2 473 SUPERFAMILY SSF48452 211 439 6.72E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS11910 87a098266fbd0e98a6c2326fb31531f4 215 Pfam PF00072 Response regulator receiver domain 18 129 2.9E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS11910 87a098266fbd0e98a6c2326fb31531f4 215 Gene3D G3DSA:3.40.50.2300 15 157 1.1E-36 T 06-07-2017 SMD11_RS11910 87a098266fbd0e98a6c2326fb31531f4 215 SUPERFAMILY SSF46894 138 215 7.82E-19 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS11910 87a098266fbd0e98a6c2326fb31531f4 215 SUPERFAMILY SSF52172 16 143 1.85E-31 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS11910 87a098266fbd0e98a6c2326fb31531f4 215 Gene3D G3DSA:1.10.10.10 158 215 7.0E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11910 87a098266fbd0e98a6c2326fb31531f4 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 5.3E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS11910 87a098266fbd0e98a6c2326fb31531f4 215 SMART SM00421 152 209 6.6E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS11910 87a098266fbd0e98a6c2326fb31531f4 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.9E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS11910 87a098266fbd0e98a6c2326fb31531f4 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.9E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS11910 87a098266fbd0e98a6c2326fb31531f4 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.9E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS11910 87a098266fbd0e98a6c2326fb31531f4 215 SMART SM00448 16 129 1.5E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS11535 9fe3fe27f4be6cd33b8d606784add6d7 227 Gene3D G3DSA:3.60.160.10 14 217 8.4E-45 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 SMD11_RS11535 9fe3fe27f4be6cd33b8d606784add6d7 227 SUPERFAMILY SSF51219 17 217 1.26E-49 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMD11_RS11535 9fe3fe27f4be6cd33b8d606784add6d7 227 Pfam PF01987 Mitochondrial biogenesis AIM24 19 215 1.1E-39 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 SMD11_RS16390 adb0963c7850d8a7440d69f9a1039fa1 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 365 1.6E-32 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS16390 adb0963c7850d8a7440d69f9a1039fa1 413 Gene3D G3DSA:3.40.47.10 12 259 7.8E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS16390 adb0963c7850d8a7440d69f9a1039fa1 413 SUPERFAMILY SSF53901 218 410 1.5E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS16390 adb0963c7850d8a7440d69f9a1039fa1 413 SMART SM00825 Beta-ketoacyl synthase 12 413 2.7E-17 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS16390 adb0963c7850d8a7440d69f9a1039fa1 413 SUPERFAMILY SSF53901 10 251 2.44E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS16390 adb0963c7850d8a7440d69f9a1039fa1 413 Gene3D G3DSA:3.40.47.10 262 411 1.3E-47 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS16390 adb0963c7850d8a7440d69f9a1039fa1 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 10 246 1.5E-35 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS16390 adb0963c7850d8a7440d69f9a1039fa1 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 161 177 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS33360 b7bc7e39f64d113a508bf242e15ad104 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 54 4.8E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS33360 b7bc7e39f64d113a508bf242e15ad104 207 Gene3D G3DSA:1.10.357.10 8 188 9.9E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS33360 b7bc7e39f64d113a508bf242e15ad104 207 SUPERFAMILY SSF46689 10 81 5.08E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS33360 b7bc7e39f64d113a508bf242e15ad104 207 SUPERFAMILY SSF48498 85 170 5.72E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS04400 1676b1e8deaa63a9509460c1906a75c6 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.7E-6 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS04400 1676b1e8deaa63a9509460c1906a75c6 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.7E-6 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS04400 1676b1e8deaa63a9509460c1906a75c6 333 Gene3D G3DSA:1.10.260.40 2 56 4.9E-26 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS04400 1676b1e8deaa63a9509460c1906a75c6 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 06-07-2017 SMD11_RS04400 1676b1e8deaa63a9509460c1906a75c6 333 SUPERFAMILY SSF53822 59 331 1.79E-68 T 06-07-2017 IPR028082 Periplasmic binding protein-like I SMD11_RS04400 1676b1e8deaa63a9509460c1906a75c6 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 47 3.3E-20 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS04400 1676b1e8deaa63a9509460c1906a75c6 333 Gene3D G3DSA:3.40.50.2300 165 328 4.5E-50 T 06-07-2017 SMD11_RS04400 1676b1e8deaa63a9509460c1906a75c6 333 SUPERFAMILY SSF47413 2 58 7.88E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS04400 1676b1e8deaa63a9509460c1906a75c6 333 Pfam PF13377 Periplasmic binding protein-like domain 168 327 1.8E-32 T 06-07-2017 SMD11_RS04400 1676b1e8deaa63a9509460c1906a75c6 333 Gene3D G3DSA:3.40.50.2300 57 164 4.9E-36 T 06-07-2017 SMD11_RS04400 1676b1e8deaa63a9509460c1906a75c6 333 SMART SM00354 1 70 1.2E-31 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS00085 eb52eb1a0ea33ac007656ab0f98b3bdc 915 SMART SM00862 15 94 3.2E-4 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS00085 eb52eb1a0ea33ac007656ab0f98b3bdc 915 Gene3D G3DSA:1.10.10.10 24 83 2.5E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00085 eb52eb1a0ea33ac007656ab0f98b3bdc 915 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 73 1.6E-5 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS00085 eb52eb1a0ea33ac007656ab0f98b3bdc 915 Gene3D G3DSA:3.40.50.300 300 403 6.1E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00085 eb52eb1a0ea33ac007656ab0f98b3bdc 915 SUPERFAMILY SSF52540 286 543 1.03E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00085 eb52eb1a0ea33ac007656ab0f98b3bdc 915 SUPERFAMILY SSF48452 707 875 1.67E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS00085 eb52eb1a0ea33ac007656ab0f98b3bdc 915 Pfam PF03704 Bacterial transcriptional activator domain 101 237 8.1E-32 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS00085 eb52eb1a0ea33ac007656ab0f98b3bdc 915 SUPERFAMILY SSF48452 99 261 1.37E-26 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS00085 eb52eb1a0ea33ac007656ab0f98b3bdc 915 SUPERFAMILY SSF46894 2 77 7.37E-10 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS00085 eb52eb1a0ea33ac007656ab0f98b3bdc 915 Gene3D G3DSA:1.25.40.10 707 893 1.0E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS00085 eb52eb1a0ea33ac007656ab0f98b3bdc 915 SMART SM01043 101 243 2.9E-37 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS00085 eb52eb1a0ea33ac007656ab0f98b3bdc 915 PRINTS PR00364 Disease resistance protein signature 311 326 6.4E-7 T 06-07-2017 SMD11_RS00085 eb52eb1a0ea33ac007656ab0f98b3bdc 915 PRINTS PR00364 Disease resistance protein signature 389 403 6.4E-7 T 06-07-2017 SMD11_RS00085 eb52eb1a0ea33ac007656ab0f98b3bdc 915 PRINTS PR00364 Disease resistance protein signature 477 491 6.4E-7 T 06-07-2017 SMD11_RS00085 eb52eb1a0ea33ac007656ab0f98b3bdc 915 Pfam PF00931 NB-ARC domain 310 538 2.2E-10 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 SMD11_RS25720 84d467eec879a3cbfe675f80113c4142 343 SUPERFAMILY SSF56784 20 273 1.97E-52 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS25720 84d467eec879a3cbfe675f80113c4142 343 Pfam PF13344 Haloacid dehalogenase-like hydrolase 24 123 1.1E-23 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA SMD11_RS25720 84d467eec879a3cbfe675f80113c4142 343 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 24 247 2.9E-29 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA SMD11_RS25720 84d467eec879a3cbfe675f80113c4142 343 Gene3D G3DSA:3.40.50.10410 93 198 5.2E-26 T 06-07-2017 IPR023215 Nitrophenylphosphatase-like domain SMD11_RS25720 84d467eec879a3cbfe675f80113c4142 343 Pfam PF13242 HAD-hyrolase-like 200 271 1.4E-16 T 06-07-2017 SMD11_RS25720 84d467eec879a3cbfe675f80113c4142 343 Gene3D G3DSA:3.40.50.1000 199 274 1.5E-31 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS25720 84d467eec879a3cbfe675f80113c4142 343 Gene3D G3DSA:3.40.50.1000 18 92 1.5E-31 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS22335 c608de34e73b52c103f1f47ee25951b9 340 SUPERFAMILY SSF81995 11 84 6.28E-8 T 06-07-2017 SMD11_RS00260 a755cabf57c34edd21fc8771340161b8 435 Gene3D G3DSA:1.10.600.10 113 430 3.7E-69 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS00260 a755cabf57c34edd21fc8771340161b8 435 SUPERFAMILY SSF48576 130 426 4.03E-39 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS29425 18977c30d29c0731b86a3e2174f1fc3b 361 SUPERFAMILY SSF51735 154 326 2.57E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29425 18977c30d29c0731b86a3e2174f1fc3b 361 Gene3D G3DSA:3.90.180.10 3 182 1.3E-55 T 06-07-2017 IPR011032 GroES-like SMD11_RS29425 18977c30d29c0731b86a3e2174f1fc3b 361 SUPERFAMILY SSF50129 310 360 8.47E-8 T 06-07-2017 IPR011032 GroES-like SMD11_RS29425 18977c30d29c0731b86a3e2174f1fc3b 361 Gene3D G3DSA:3.40.50.720 183 302 3.6E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29425 18977c30d29c0731b86a3e2174f1fc3b 361 Pfam PF00107 Zinc-binding dehydrogenase 190 320 6.4E-31 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS29425 18977c30d29c0731b86a3e2174f1fc3b 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 361 1.6E-212 T 06-07-2017 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 SMD11_RS29425 18977c30d29c0731b86a3e2174f1fc3b 361 SMART SM00829 14 359 2.0E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS29425 18977c30d29c0731b86a3e2174f1fc3b 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD11_RS29425 18977c30d29c0731b86a3e2174f1fc3b 361 SUPERFAMILY SSF50129 4 186 4.57E-55 T 06-07-2017 IPR011032 GroES-like SMD11_RS29425 18977c30d29c0731b86a3e2174f1fc3b 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 5.0E-27 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 Gene3D G3DSA:3.40.50.300 19 315 1.9E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 25 156 1.4E-12 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 SUPERFAMILY SSF54211 520 635 1.01E-34 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 Gene3D G3DSA:3.30.70.870 444 514 2.1E-23 T 06-07-2017 SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 Pfam PF03144 Elongation factor Tu domain 2 353 429 1.9E-9 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 SUPERFAMILY SSF54980 443 520 3.96E-17 T 06-07-2017 IPR009022 Elongation factor G, III-V domain SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 SMART SM00889 519 637 1.2E-56 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 Pfam PF00009 Elongation factor Tu GTP binding domain 23 249 2.5E-29 T 06-07-2017 SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 SUPERFAMILY SSF54980 640 728 4.8E-21 T 06-07-2017 IPR009022 Elongation factor G, III-V domain SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 PRINTS PR00315 GTP-binding elongation factor signature 26 39 5.1E-6 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 PRINTS PR00315 GTP-binding elongation factor signature 92 102 5.1E-6 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 PRINTS PR00315 GTP-binding elongation factor signature 108 119 5.1E-6 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 Pfam PF00679 Elongation factor G C-terminus 640 726 4.6E-22 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 Pfam PF14492 Elongation Factor G, domain II 443 514 7.1E-23 T 06-07-2017 IPR009022 Elongation factor G, III-V domain SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 SUPERFAMILY SSF50447 329 440 2.17E-22 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 Gene3D G3DSA:3.30.230.10 523 641 1.1E-46 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 SUPERFAMILY SSF52540 21 310 3.83E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 SMART SM00838 639 727 4.8E-19 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 Pfam PF03764 Elongation factor G, domain IV 519 635 2.9E-39 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 Gene3D G3DSA:3.30.70.240 642 727 5.1E-23 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain SMD11_RS27140 5456250d300ec0d96ce1992303d7ff14 735 Gene3D G3DSA:2.40.30.10 333 443 1.2E-27 T 06-07-2017 SMD11_RS33670 b0cbfd1d3ba6f4e42643e6881583c290 861 Gene3D G3DSA:3.30.450.40 154 302 4.3E-8 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS33670 b0cbfd1d3ba6f4e42643e6881583c290 861 SUPERFAMILY SSF81606 660 806 1.7E-10 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS33670 b0cbfd1d3ba6f4e42643e6881583c290 861 SMART SM01012 30 85 2.8E-8 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 SMD11_RS33670 b0cbfd1d3ba6f4e42643e6881583c290 861 SUPERFAMILY SSF55781 147 302 3.27E-9 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS33670 b0cbfd1d3ba6f4e42643e6881583c290 861 SUPERFAMILY SSF55785 496 600 7.61E-8 T 06-07-2017 IPR000014 PAS domain SMD11_RS33670 b0cbfd1d3ba6f4e42643e6881583c290 861 Pfam PF08448 PAS fold 533 599 1.3E-5 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS33670 b0cbfd1d3ba6f4e42643e6881583c290 861 Gene3D G3DSA:1.10.10.10 33 79 1.6E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33670 b0cbfd1d3ba6f4e42643e6881583c290 861 SUPERFAMILY SSF52172 18 79 4.57E-6 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS33670 b0cbfd1d3ba6f4e42643e6881583c290 861 SMART SM00331 646 857 2.6E-29 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS33670 b0cbfd1d3ba6f4e42643e6881583c290 861 Pfam PF03861 ANTAR domain 32 79 3.1E-9 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 SMD11_RS33670 b0cbfd1d3ba6f4e42643e6881583c290 861 Pfam PF13185 GAF domain 165 299 3.8E-10 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS33670 b0cbfd1d3ba6f4e42643e6881583c290 861 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 672 855 2.7E-41 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS33670 b0cbfd1d3ba6f4e42643e6881583c290 861 Gene3D G3DSA:3.30.450.20 479 596 9.4E-11 T 06-07-2017 SMD11_RS19290 201310e071b507d6e5abf307d225e983 398 Pfam PF00144 Beta-lactamase 45 385 5.5E-51 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS19290 201310e071b507d6e5abf307d225e983 398 SUPERFAMILY SSF56601 153 382 1.03E-65 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS19290 201310e071b507d6e5abf307d225e983 398 SUPERFAMILY SSF56601 40 126 1.03E-65 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS19290 201310e071b507d6e5abf307d225e983 398 Gene3D G3DSA:3.40.710.10 51 380 9.1E-66 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 SMART SM00220 15 270 1.1E-37 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 Pfam PF13570 PQQ-like domain 470 502 0.0021 T 06-07-2017 IPR025666 Pyrrolo-quinoline quinone-like domain SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 SMART SM00564 516 547 36.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 SMART SM00564 554 586 9.2 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 SMART SM00564 482 511 32.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 SMART SM00564 729 760 44.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 SMART SM00564 644 674 69.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 SMART SM00564 689 720 1.5E-6 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 SMART SM00564 598 629 0.036 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 SMART SM00564 809 840 0.0021 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 SMART SM00564 768 800 0.98 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 Pfam PF13360 PQQ-like domain 518 672 1.4E-17 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 Pfam PF13360 PQQ-like domain 703 838 3.2E-18 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 SUPERFAMILY SSF50998 648 834 1.33E-31 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 Gene3D G3DSA:1.10.510.10 98 262 1.7E-38 T 06-07-2017 SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 SUPERFAMILY SSF56112 11 271 1.75E-60 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 Gene3D G3DSA:2.140.10.10 528 833 1.2E-60 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 Gene3D G3DSA:2.140.10.10 442 494 1.2E-60 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 Pfam PF00069 Protein kinase domain 15 261 1.9E-36 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 SUPERFAMILY SSF50998 470 497 1.83E-24 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 SUPERFAMILY SSF50998 531 677 1.83E-24 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 Gene3D G3DSA:3.30.200.20 6 81 1.3E-12 T 06-07-2017 SMD11_RS19410 89f06a470ed2eb22a140859c721b47e4 840 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS30105 c782c27451e67a31531cb5fa49423745 528 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 407 493 5.5E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS30105 c782c27451e67a31531cb5fa49423745 528 Gene3D G3DSA:3.30.565.10 401 496 2.3E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS30105 c782c27451e67a31531cb5fa49423745 528 SUPERFAMILY SSF55874 380 492 3.01E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS30105 c782c27451e67a31531cb5fa49423745 528 Pfam PF07730 Histidine kinase 284 351 5.9E-21 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS05570 9b0e0a19332ab3215aba2b1967b3a96d 368 Gene3D G3DSA:1.10.540.10 4 108 1.5E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS05570 9b0e0a19332ab3215aba2b1967b3a96d 368 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 87 3.3E-6 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS05570 9b0e0a19332ab3215aba2b1967b3a96d 368 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 230 351 4.6E-23 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain SMD11_RS05570 9b0e0a19332ab3215aba2b1967b3a96d 368 Gene3D G3DSA:1.20.140.10 194 365 9.6E-30 T 06-07-2017 SMD11_RS05570 9b0e0a19332ab3215aba2b1967b3a96d 368 Gene3D G3DSA:2.40.110.10 111 193 2.5E-27 T 06-07-2017 SMD11_RS05570 9b0e0a19332ab3215aba2b1967b3a96d 368 SUPERFAMILY SSF47203 233 348 8.57E-12 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS05570 9b0e0a19332ab3215aba2b1967b3a96d 368 PIRSF PIRSF016578 2 368 1.2E-130 T 06-07-2017 SMD11_RS05570 9b0e0a19332ab3215aba2b1967b3a96d 368 SUPERFAMILY SSF56645 11 199 3.93E-33 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS18755 0f294b056432df4b8cf22a90cebd053c 218 Pfam PF13460 NAD(P)H-binding 7 194 2.5E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18755 0f294b056432df4b8cf22a90cebd053c 218 Gene3D G3DSA:3.40.50.720 1 209 1.2E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18755 0f294b056432df4b8cf22a90cebd053c 218 SUPERFAMILY SSF51735 1 208 2.17E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS09705 73069f960793e0836f65b27a95faa203 209 Pfam PF02620 Uncharacterized ACR, COG1399 66 186 3.8E-34 T 06-07-2017 IPR003772 Protein of unknown function DUF177 SMD11_RS20010 9974f22f99b46d36e52484b41e15b7af 679 PRINTS PR01036 Tetracycline resistance protein TetB signature 29 53 2.5E-6 T 06-07-2017 SMD11_RS20010 9974f22f99b46d36e52484b41e15b7af 679 PRINTS PR01036 Tetracycline resistance protein TetB signature 119 139 2.5E-6 T 06-07-2017 SMD11_RS20010 9974f22f99b46d36e52484b41e15b7af 679 PRINTS PR01036 Tetracycline resistance protein TetB signature 413 432 2.5E-6 T 06-07-2017 SMD11_RS20010 9974f22f99b46d36e52484b41e15b7af 679 PRINTS PR01036 Tetracycline resistance protein TetB signature 149 173 2.5E-6 T 06-07-2017 SMD11_RS20010 9974f22f99b46d36e52484b41e15b7af 679 PRINTS PR01036 Tetracycline resistance protein TetB signature 371 391 2.5E-6 T 06-07-2017 SMD11_RS20010 9974f22f99b46d36e52484b41e15b7af 679 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 26 499 7.5E-78 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS20010 9974f22f99b46d36e52484b41e15b7af 679 Pfam PF07690 Major Facilitator Superfamily 31 422 1.9E-50 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS20010 9974f22f99b46d36e52484b41e15b7af 679 SUPERFAMILY SSF103473 260 432 7.72E-69 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS20010 9974f22f99b46d36e52484b41e15b7af 679 SUPERFAMILY SSF103473 476 501 7.72E-69 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS20010 9974f22f99b46d36e52484b41e15b7af 679 SUPERFAMILY SSF103473 13 206 7.72E-69 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS20010 9974f22f99b46d36e52484b41e15b7af 679 Gene3D G3DSA:1.20.1250.20 276 433 3.4E-24 T 06-07-2017 SMD11_RS20010 9974f22f99b46d36e52484b41e15b7af 679 Gene3D G3DSA:1.20.1250.20 26 200 7.9E-31 T 06-07-2017 SMD11_RS20010 9974f22f99b46d36e52484b41e15b7af 679 Gene3D G3DSA:1.20.1250.20 477 508 3.4E-24 T 06-07-2017 SMD11_RS20010 9974f22f99b46d36e52484b41e15b7af 679 Gene3D G3DSA:1.10.10.10 559 666 3.7E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS09875 3cea13d8f71704e342c9d22704892d3e 1330 Pfam PF00672 HAMP domain 424 508 7.7E-18 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09875 3cea13d8f71704e342c9d22704892d3e 1330 Pfam PF08376 Nitrate and nitrite sensing 160 404 1.2E-38 T 06-07-2017 IPR013587 Nitrate/nitrite sensing protein SMD11_RS09875 3cea13d8f71704e342c9d22704892d3e 1330 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 627 733 2.3E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS09875 3cea13d8f71704e342c9d22704892d3e 1330 SMART SM00304 442 512 6.0E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09875 3cea13d8f71704e342c9d22704892d3e 1330 SMART SM00387 624 735 1.6E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS09875 3cea13d8f71704e342c9d22704892d3e 1330 Gene3D G3DSA:3.30.565.10 591 736 2.8E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS09875 3cea13d8f71704e342c9d22704892d3e 1330 SUPERFAMILY SSF55874 613 732 1.3E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS28090 83c257abb00216fb0bd54498a441f6bb 793 ProSitePatterns PS00129 Glycosyl hydrolases family 31 active site. 446 453 - T 06-07-2017 IPR030458 Glycosyl hydrolases family 31, active site SMD11_RS28090 83c257abb00216fb0bd54498a441f6bb 793 SUPERFAMILY SSF74650 87 281 6.28E-14 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMD11_RS28090 83c257abb00216fb0bd54498a441f6bb 793 SUPERFAMILY SSF51445 286 633 2.68E-81 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS28090 83c257abb00216fb0bd54498a441f6bb 793 Pfam PF13802 Galactose mutarotase-like 180 245 9.4E-10 T 06-07-2017 IPR025887 Glycoside hydrolase family 31, N-terminal domain SMD11_RS28090 83c257abb00216fb0bd54498a441f6bb 793 SUPERFAMILY SSF51011 635 714 4.1E-20 T 06-07-2017 SMD11_RS28090 83c257abb00216fb0bd54498a441f6bb 793 Pfam PF01055 Glycosyl hydrolases family 31 278 719 9.6E-125 T 06-07-2017 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 Gene3D G3DSA:3.30.300.30 886 1008 2.8E-35 T 06-07-2017 SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 Pfam PF00501 AMP-binding enzyme 486 890 9.6E-100 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 Pfam PF00550 Phosphopantetheine attachment site 1006 1066 6.9E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 Gene3D G3DSA:3.40.50.980 655 801 2.7E-48 T 06-07-2017 SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 Gene3D G3DSA:2.30.38.10 802 880 1.2E-28 T 06-07-2017 SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1028 1043 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 Gene3D G3DSA:3.40.50.1820 1270 1337 1.9E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 Gene3D G3DSA:3.40.50.1820 1080 1200 1.9E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 SMART SM00824 Thioesterase 1096 1336 4.1E-4 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 Pfam PF13193 AMP-binding enzyme C-terminal domain 899 979 4.3E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 SUPERFAMILY SSF52777 27 202 2.0E-37 T 06-07-2017 SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 506 913 5.5E-135 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 Gene3D G3DSA:3.40.50.980 480 649 1.4E-44 T 06-07-2017 SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 SMART SM00823 Phosphopantetheine attachment site 1004 1073 0.0014 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 Pfam PF00668 Condensation domain 25 321 8.6E-48 T 06-07-2017 IPR001242 Condensation domain SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 SUPERFAMILY SSF47336 997 1066 6.15E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 SUPERFAMILY SSF53474 1077 1336 1.97E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 SUPERFAMILY SSF56801 446 1017 7.33E-158 T 06-07-2017 SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 SUPERFAMILY SSF52777 212 471 8.89E-42 T 06-07-2017 SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 Pfam PF00975 Thioesterase domain 1094 1321 1.6E-26 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 ProSitePatterns PS00455 Putative AMP-binding domain signature. 634 645 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS06355 aec679c69e8f064cc36924c3c0580f1b 1340 Gene3D G3DSA:1.10.1200.10 1009 1071 3.0E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS33645 567a9d8288450f777a02d2aaff0bc900 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 3.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS33645 567a9d8288450f777a02d2aaff0bc900 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 3.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS33645 567a9d8288450f777a02d2aaff0bc900 210 Gene3D G3DSA:1.10.10.60 5 60 5.9E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS33645 567a9d8288450f777a02d2aaff0bc900 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 63 2.7E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS33645 567a9d8288450f777a02d2aaff0bc900 210 Gene3D G3DSA:1.10.357.10 61 203 1.3E-13 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS33645 567a9d8288450f777a02d2aaff0bc900 210 SUPERFAMILY SSF46689 9 81 2.39E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS32920 cf970a021ab7eddaa11862856338edbc 106 SUPERFAMILY SSF47336 4 83 5.37E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32920 cf970a021ab7eddaa11862856338edbc 106 SMART SM00823 Phosphopantetheine attachment site 8 79 9.5E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32920 cf970a021ab7eddaa11862856338edbc 106 Pfam PF00550 Phosphopantetheine attachment site 9 75 1.6E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32920 cf970a021ab7eddaa11862856338edbc 106 Gene3D G3DSA:1.10.1200.10 5 77 2.6E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08660 f08aa33e44b4f3d97751e3c047c9c4de 435 Pfam PF00285 Citrate synthase, C-terminal domain 83 414 1.7E-65 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS08660 f08aa33e44b4f3d97751e3c047c9c4de 435 PRINTS PR00143 Citrate synthase signature 242 257 2.5E-23 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS08660 f08aa33e44b4f3d97751e3c047c9c4de 435 PRINTS PR00143 Citrate synthase signature 391 405 2.5E-23 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS08660 f08aa33e44b4f3d97751e3c047c9c4de 435 PRINTS PR00143 Citrate synthase signature 264 292 2.5E-23 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS08660 f08aa33e44b4f3d97751e3c047c9c4de 435 PRINTS PR00143 Citrate synthase signature 371 387 2.5E-23 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS08660 f08aa33e44b4f3d97751e3c047c9c4de 435 PRINTS PR00143 Citrate synthase signature 317 337 2.5E-23 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS08660 f08aa33e44b4f3d97751e3c047c9c4de 435 SUPERFAMILY SSF48256 75 432 1.96E-70 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS08660 f08aa33e44b4f3d97751e3c047c9c4de 435 Gene3D G3DSA:1.10.580.10 85 304 1.5E-41 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SMD11_RS08660 f08aa33e44b4f3d97751e3c047c9c4de 435 Pfam PF12728 Helix-turn-helix domain 23 73 2.4E-8 T 06-07-2017 SMD11_RS08660 f08aa33e44b4f3d97751e3c047c9c4de 435 SUPERFAMILY SSF46955 23 71 2.01E-6 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS08660 f08aa33e44b4f3d97751e3c047c9c4de 435 Gene3D G3DSA:1.10.10.60 21 44 1.2E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS08660 f08aa33e44b4f3d97751e3c047c9c4de 435 Gene3D G3DSA:1.10.230.10 305 381 1.4E-12 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 SMD11_RS11985 b97f710367bf495557effb879dd9a435 347 SUPERFAMILY SSF52540 8 260 3.67E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11985 b97f710367bf495557effb879dd9a435 347 SMART SM00382 45 238 2.6E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS11985 b97f710367bf495557effb879dd9a435 347 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS11985 b97f710367bf495557effb879dd9a435 347 Gene3D G3DSA:3.40.50.300 7 262 4.9E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11985 b97f710367bf495557effb879dd9a435 347 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 307 2.1E-16 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS11985 b97f710367bf495557effb879dd9a435 347 Pfam PF00005 ABC transporter 37 188 2.7E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS11985 b97f710367bf495557effb879dd9a435 347 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 240 314 1.4E-21 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 SMART SM01294 241 308 0.0049 T 06-07-2017 SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 718 831 1.3E-14 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 Pfam PF08659 KR domain 1 132 8.2E-35 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 Pfam PF12680 SnoaL-like domain 1161 1266 2.8E-14 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 Gene3D G3DSA:3.10.450.50 1153 1276 3.6E-29 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 134 5.9E-9 T 06-07-2017 SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 Gene3D G3DSA:1.10.1200.10 237 312 1.5E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 SMART SM00825 Beta-ketoacyl synthase 344 768 1.3E-186 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 Pfam PF00698 Acyl transferase domain 888 1000 3.3E-12 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 Gene3D G3DSA:3.40.366.10 887 1041 1.7E-25 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 SMART SM00823 Phosphopantetheine attachment site 240 312 3.8E-29 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 SUPERFAMILY SSF53901 340 711 2.66E-93 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 506 522 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 342 590 5.4E-72 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 SUPERFAMILY SSF47336 234 357 3.93E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 Gene3D G3DSA:3.40.47.10 339 602 2.2E-80 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 Gene3D G3DSA:3.40.47.10 603 768 1.0E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 Pfam PF00550 Phosphopantetheine attachment site 243 308 1.3E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 Gene3D G3DSA:3.40.50.720 1 170 9.0E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 SUPERFAMILY SSF51735 2 195 1.32E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 887 1059 1.6E-10 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 598 713 1.1E-41 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 SUPERFAMILY SSF52151 887 1041 2.28E-23 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS04455 f012824ec1a02a5f32b778e16ffc6c43 1278 SUPERFAMILY SSF54427 1153 1275 4.93E-22 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 SUPERFAMILY SSF56719 436 676 3.4E-82 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 SMART SM00433 67 674 0.0 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 ProSitePatterns PS00177 DNA topoisomerase II signature. 464 472 - T 06-07-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 38 681 1.3E-285 T 06-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 Pfam PF01751 Toprim domain 461 572 4.3E-17 T 06-07-2017 IPR006171 Toprim domain SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR01159 DNA gyrase subunit B signature 212 227 4.5E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR01159 DNA gyrase subunit B signature 650 666 4.5E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR01159 DNA gyrase subunit B signature 259 281 4.5E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR01159 DNA gyrase subunit B signature 634 646 4.5E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR01159 DNA gyrase subunit B signature 227 240 4.5E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR01159 DNA gyrase subunit B signature 354 370 4.5E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR01159 DNA gyrase subunit B signature 416 436 4.5E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR01159 DNA gyrase subunit B signature 512 521 4.5E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR01159 DNA gyrase subunit B signature 402 416 4.5E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR01159 DNA gyrase subunit B signature 284 302 4.5E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR01159 DNA gyrase subunit B signature 38 48 4.5E-75 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 35 681 88.341 T 06-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 Gene3D G3DSA:3.40.50.670 446 663 1.5E-87 T 06-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 Gene3D G3DSA:3.30.565.10 38 243 6.6E-86 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 SUPERFAMILY SSF54211 260 433 5.5E-55 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 Gene3D G3DSA:3.30.230.10 259 434 1.4E-71 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 Pfam PF00204 DNA gyrase B 260 432 3.6E-62 T 06-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 SMART SM00387 63 207 3.7E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR00418 DNA topoisomerase II family signature 528 544 1.5E-66 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR00418 DNA topoisomerase II family signature 102 115 1.5E-66 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR00418 DNA topoisomerase II family signature 67 82 1.5E-66 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR00418 DNA topoisomerase II family signature 613 629 1.5E-66 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR00418 DNA topoisomerase II family signature 145 159 1.5E-66 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR00418 DNA topoisomerase II family signature 566 578 1.5E-66 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR00418 DNA topoisomerase II family signature 462 476 1.5E-66 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR00418 DNA topoisomerase II family signature 310 323 1.5E-66 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 PRINTS PR00418 DNA topoisomerase II family signature 546 563 1.5E-66 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 612 670 2.4E-24 T 06-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 SUPERFAMILY SSF55874 38 244 1.25E-68 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16935 07e746928db9c09805b8249f3e062163 681 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 65 205 1.4E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16205 66b9de726a53cfc865b079df7ff432f4 325 SUPERFAMILY SSF54637 35 181 7.14E-16 T 06-07-2017 IPR029069 HotDog domain SMD11_RS16205 66b9de726a53cfc865b079df7ff432f4 325 SUPERFAMILY SSF50249 190 311 1.71E-34 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS16205 66b9de726a53cfc865b079df7ff432f4 325 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 205 241 2.3E-7 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal SMD11_RS16205 66b9de726a53cfc865b079df7ff432f4 325 Gene3D G3DSA:3.10.129.10 34 167 5.6E-11 T 06-07-2017 IPR029069 HotDog domain SMD11_RS16205 66b9de726a53cfc865b079df7ff432f4 325 Pfam PF13452 N-terminal half of MaoC dehydratase 32 161 2.3E-12 T 06-07-2017 SMD11_RS16205 66b9de726a53cfc865b079df7ff432f4 325 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 243 304 1.3E-21 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 SUPERFAMILY SSF48592 6 133 3.16E-72 T 06-07-2017 SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 SUPERFAMILY SSF48592 406 521 3.16E-72 T 06-07-2017 SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 Gene3D G3DSA:1.10.560.10 371 518 8.6E-38 T 06-07-2017 IPR027413 GroEL-like equatorial domain SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 SUPERFAMILY SSF54849 136 203 3.43E-25 T 06-07-2017 SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 Gene3D G3DSA:3.50.7.10 195 370 6.5E-89 T 06-07-2017 IPR027409 GroEL-like apical domain SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 524 2.5E-93 T 06-07-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 PRINTS PR00298 60kDa chaperonin signature 350 375 2.6E-71 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 PRINTS PR00298 60kDa chaperonin signature 26 52 2.6E-71 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 PRINTS PR00298 60kDa chaperonin signature 82 109 2.6E-71 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 PRINTS PR00298 60kDa chaperonin signature 268 291 2.6E-71 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 PRINTS PR00298 60kDa chaperonin signature 398 419 2.6E-71 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 06-07-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 Gene3D G3DSA:1.10.560.10 6 194 5.8E-44 T 06-07-2017 IPR027413 GroEL-like equatorial domain SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 Hamap MF_00600 60 kDa chaperonin [groL]. 1 538 41.462 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 526 9.9E-244 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 SMD11_RS19225 453d5e9ed6b7aa3c5d8c135f870c1299 540 SUPERFAMILY SSF52029 184 376 9.77E-79 T 06-07-2017 IPR027409 GroEL-like apical domain SMD11_RS00515 2cc7f795a5e385c5495653366851ab81 103 Gene3D G3DSA:1.10.260.40 41 93 1.3E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS00515 2cc7f795a5e385c5495653366851ab81 103 SMART SM00530 44 96 2.5E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS00515 2cc7f795a5e385c5495653366851ab81 103 Pfam PF13560 Helix-turn-helix domain 42 92 1.3E-8 T 06-07-2017 SMD11_RS00515 2cc7f795a5e385c5495653366851ab81 103 SUPERFAMILY SSF47413 39 95 1.91E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS18665 abb16ad6be0b2ef23d5dd9dd4a90fed6 661 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 560 631 6.9E-9 T 06-07-2017 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II SMD11_RS18665 abb16ad6be0b2ef23d5dd9dd4a90fed6 661 ProSitePatterns PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 636 646 - T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS18665 abb16ad6be0b2ef23d5dd9dd4a90fed6 661 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 62 250 8.6E-26 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 SMD11_RS18665 abb16ad6be0b2ef23d5dd9dd4a90fed6 661 Gene3D G3DSA:3.40.50.970 274 468 8.6E-73 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS18665 abb16ad6be0b2ef23d5dd9dd4a90fed6 661 SUPERFAMILY SSF52922 559 660 1.88E-15 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS18665 abb16ad6be0b2ef23d5dd9dd4a90fed6 661 Gene3D G3DSA:3.40.50.920 559 658 4.1E-11 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS18665 abb16ad6be0b2ef23d5dd9dd4a90fed6 661 SUPERFAMILY SSF52518 277 544 3.04E-59 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS18665 abb16ad6be0b2ef23d5dd9dd4a90fed6 661 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 54 654 9.0E-200 T 06-07-2017 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 SMD11_RS18665 abb16ad6be0b2ef23d5dd9dd4a90fed6 661 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 305 518 8.8E-51 T 06-07-2017 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 SMD11_RS18665 abb16ad6be0b2ef23d5dd9dd4a90fed6 661 Gene3D G3DSA:3.40.920.10 54 253 7.3E-25 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 SMD11_RS18665 abb16ad6be0b2ef23d5dd9dd4a90fed6 661 SUPERFAMILY SSF53323 56 259 1.96E-17 T 06-07-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 SMD11_RS31620 27ef5dc517c1fe3a67eb7e70c77028c0 396 SUPERFAMILY SSF55874 241 391 9.95E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS31620 27ef5dc517c1fe3a67eb7e70c77028c0 396 SMART SM00387 290 394 6.8E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS31620 27ef5dc517c1fe3a67eb7e70c77028c0 396 SMART SM00388 194 252 5.3E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS31620 27ef5dc517c1fe3a67eb7e70c77028c0 396 SUPERFAMILY SSF158472 135 190 3.27E-5 T 06-07-2017 SMD11_RS31620 27ef5dc517c1fe3a67eb7e70c77028c0 396 SMART SM00304 134 193 2.5E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS31620 27ef5dc517c1fe3a67eb7e70c77028c0 396 Pfam PF00512 His Kinase A (phospho-acceptor) domain 195 251 1.9E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS31620 27ef5dc517c1fe3a67eb7e70c77028c0 396 Gene3D G3DSA:1.10.287.130 184 238 1.0E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS31620 27ef5dc517c1fe3a67eb7e70c77028c0 396 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 290 393 1.2E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS31620 27ef5dc517c1fe3a67eb7e70c77028c0 396 Gene3D G3DSA:3.30.565.10 239 391 4.5E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS31620 27ef5dc517c1fe3a67eb7e70c77028c0 396 Pfam PF00672 HAMP domain 115 190 1.3E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS31620 27ef5dc517c1fe3a67eb7e70c77028c0 396 SUPERFAMILY SSF47384 178 251 4.32E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS31295 51c93d5aaa99dcb94b778d8ffae9df36 188 Pfam PF07291 Methylamine utilisation protein MauE 8 145 3.1E-11 T 06-07-2017 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 SMD11_RS25655 68b608cb4165d97831ba0e0d5ec18d39 317 Pfam PF01145 SPFH domain / Band 7 family 25 194 2.5E-35 T 06-07-2017 IPR001107 Band 7 domain SMD11_RS25655 68b608cb4165d97831ba0e0d5ec18d39 317 SUPERFAMILY SSF117892 52 186 2.88E-39 T 06-07-2017 IPR001107 Band 7 domain SMD11_RS25655 68b608cb4165d97831ba0e0d5ec18d39 317 PRINTS PR00721 Stomatin signature 131 154 1.4E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 SMD11_RS25655 68b608cb4165d97831ba0e0d5ec18d39 317 PRINTS PR00721 Stomatin signature 174 195 1.4E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 SMD11_RS25655 68b608cb4165d97831ba0e0d5ec18d39 317 PRINTS PR00721 Stomatin signature 111 128 1.4E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 SMD11_RS25655 68b608cb4165d97831ba0e0d5ec18d39 317 PRINTS PR00721 Stomatin signature 28 50 1.4E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 SMD11_RS25655 68b608cb4165d97831ba0e0d5ec18d39 317 PRINTS PR00721 Stomatin signature 155 173 1.4E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 SMD11_RS25655 68b608cb4165d97831ba0e0d5ec18d39 317 PRINTS PR00721 Stomatin signature 76 97 1.4E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 SMD11_RS25655 68b608cb4165d97831ba0e0d5ec18d39 317 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 06-07-2017 IPR018080 Band 7/stomatin-like, conserved site SMD11_RS25655 68b608cb4165d97831ba0e0d5ec18d39 317 SMART SM00244 21 179 1.3E-52 T 06-07-2017 IPR001107 Band 7 domain SMD11_RS09935 5f804e2936d0f078c704b4b50c6791aa 519 SUPERFAMILY SSF51905 265 350 9.04E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS09935 5f804e2936d0f078c704b4b50c6791aa 519 SUPERFAMILY SSF51905 3 173 9.04E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS09935 5f804e2936d0f078c704b4b50c6791aa 519 Gene3D G3DSA:3.50.50.60 276 315 1.4E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS09935 5f804e2936d0f078c704b4b50c6791aa 519 Gene3D G3DSA:3.50.50.60 1 163 1.4E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS09935 5f804e2936d0f078c704b4b50c6791aa 519 Pfam PF01494 FAD binding domain 3 340 1.4E-86 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS09935 5f804e2936d0f078c704b4b50c6791aa 519 Gene3D G3DSA:3.30.9.10 164 271 1.5E-10 T 06-07-2017 SMD11_RS09935 5f804e2936d0f078c704b4b50c6791aa 519 Gene3D G3DSA:3.30.9.10 326 349 1.5E-10 T 06-07-2017 SMD11_RS09935 5f804e2936d0f078c704b4b50c6791aa 519 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 4.1E-42 T 06-07-2017 SMD11_RS09935 5f804e2936d0f078c704b4b50c6791aa 519 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 4.1E-42 T 06-07-2017 SMD11_RS09935 5f804e2936d0f078c704b4b50c6791aa 519 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 4.1E-42 T 06-07-2017 SMD11_RS09935 5f804e2936d0f078c704b4b50c6791aa 519 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 4.1E-42 T 06-07-2017 SMD11_RS09935 5f804e2936d0f078c704b4b50c6791aa 519 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 329 4.1E-42 T 06-07-2017 SMD11_RS09935 5f804e2936d0f078c704b4b50c6791aa 519 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 329 345 4.1E-42 T 06-07-2017 SMD11_RS09935 5f804e2936d0f078c704b4b50c6791aa 519 SUPERFAMILY SSF52833 386 509 1.21E-7 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS19995 35f4a3298621cad8c50a8cbae6ded4ff 738 SUPERFAMILY SSF82866 463 695 2.49E-26 T 06-07-2017 SMD11_RS19995 35f4a3298621cad8c50a8cbae6ded4ff 738 Gene3D G3DSA:1.20.1640.10 475 698 1.0E-30 T 06-07-2017 SMD11_RS19995 35f4a3298621cad8c50a8cbae6ded4ff 738 Gene3D G3DSA:1.20.1640.10 145 336 3.1E-32 T 06-07-2017 SMD11_RS19995 35f4a3298621cad8c50a8cbae6ded4ff 738 SUPERFAMILY SSF82866 141 330 1.14E-31 T 06-07-2017 SMD11_RS19995 35f4a3298621cad8c50a8cbae6ded4ff 738 Pfam PF03176 MMPL family 433 695 1.1E-33 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 SMD11_RS19995 35f4a3298621cad8c50a8cbae6ded4ff 738 Pfam PF03176 MMPL family 45 366 7.1E-77 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 SMD11_RS18995 9c4805396d407dc6d4c1ea22e171348d 219 PRINTS PR00094 Adenylate kinase signature 32 46 4.3E-37 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMD11_RS18995 9c4805396d407dc6d4c1ea22e171348d 219 PRINTS PR00094 Adenylate kinase signature 4 17 4.3E-37 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMD11_RS18995 9c4805396d407dc6d4c1ea22e171348d 219 PRINTS PR00094 Adenylate kinase signature 81 97 4.3E-37 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMD11_RS18995 9c4805396d407dc6d4c1ea22e171348d 219 PRINTS PR00094 Adenylate kinase signature 161 176 4.3E-37 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMD11_RS18995 9c4805396d407dc6d4c1ea22e171348d 219 PRINTS PR00094 Adenylate kinase signature 178 192 4.3E-37 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMD11_RS18995 9c4805396d407dc6d4c1ea22e171348d 219 SUPERFAMILY SSF57774 126 164 2.36E-11 T 06-07-2017 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 SMD11_RS18995 9c4805396d407dc6d4c1ea22e171348d 219 Pfam PF00406 Adenylate kinase 5 191 5.8E-58 T 06-07-2017 SMD11_RS18995 9c4805396d407dc6d4c1ea22e171348d 219 Hamap MF_00235 Adenylate kinase [adk]. 1 214 50.714 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SMD11_RS18995 9c4805396d407dc6d4c1ea22e171348d 219 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 06-07-2017 SMD11_RS18995 9c4805396d407dc6d4c1ea22e171348d 219 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 9.7E-78 T 06-07-2017 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 SMD11_RS18995 9c4805396d407dc6d4c1ea22e171348d 219 Pfam PF05191 Adenylate kinase, active site lid 127 163 4.7E-14 T 06-07-2017 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 SMD11_RS18995 9c4805396d407dc6d4c1ea22e171348d 219 Gene3D G3DSA:3.40.50.300 1 212 5.0E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18995 9c4805396d407dc6d4c1ea22e171348d 219 SUPERFAMILY SSF52540 162 214 5.4E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18995 9c4805396d407dc6d4c1ea22e171348d 219 SUPERFAMILY SSF52540 1 131 5.4E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF51735 3367 3590 4.21E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.40.50.720 1502 1595 2.8E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF51735 1176 1344 2.89E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1989 2004 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SMART SM00825 Beta-ketoacyl synthase 2056 2482 6.4E-222 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SMART SM00825 Beta-ketoacyl synthase 36 456 2.7E-209 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.40.50.1820 3747 4024 2.3E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF55048 2691 2752 5.23E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF14765 Polyketide synthase dehydratase 2926 3184 1.2E-35 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF14765 Polyketide synthase dehydratase 898 1165 6.3E-52 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SMART SM01294 1963 2030 6.7E-6 T 06-07-2017 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF13602 Zinc-binding dehydrogenase 1542 1669 1.3E-19 T 06-07-2017 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.90.180.10 1380 1501 4.3E-42 T 06-07-2017 IPR011032 GroES-like SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.40.47.10 31 290 1.4E-89 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.40.47.10 2051 2316 2.5E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SMART SM00823 Phosphopantetheine attachment site 1962 2034 1.9E-32 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SMART SM00823 Phosphopantetheine attachment site 3649 3721 5.9E-27 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF53901 2051 2427 7.61E-103 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF52151 542 658 5.75E-77 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF52151 717 832 5.75E-77 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF00550 Phosphopantetheine attachment site 3651 3717 7.1E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF00550 Phosphopantetheine attachment site 1964 2030 1.6E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF08659 KR domain 3369 3546 9.1E-57 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF08659 KR domain 1679 1857 2.3E-60 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2432 2549 2.2E-14 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 406 518 2.6E-12 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF00698 Acyl transferase domain 545 850 4.0E-59 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF00698 Acyl transferase domain 2573 2878 6.1E-60 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 191 207 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2217 2233 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SMART SM00826 2926 3076 2.5E-61 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SMART SM00826 898 1055 7.4E-77 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 545 831 2.6E-123 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2573 2859 1.4E-120 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF50129 1381 1500 1.73E-27 T 06-07-2017 IPR011032 GroES-like SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF00975 Thioesterase domain 3807 3939 7.5E-14 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF47336 3645 3734 4.16E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 286 403 4.7E-45 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2312 2429 3.6E-44 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF53901 31 401 6.02E-101 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SMART SM00824 Thioesterase 3803 4022 4.9E-89 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1495 1516 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF51735 3193 3353 2.05E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF51735 1676 1875 2.25E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF55048 663 724 1.31E-9 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.40.50.720 3369 3580 2.4E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.40.50.720 1678 1861 3.7E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.40.50.720 1928 1947 3.7E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3369 3548 4.7E-50 T 06-07-2017 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1679 1859 3.5E-64 T 06-07-2017 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.40.47.10 2317 2482 7.6E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.40.47.10 291 456 5.7E-64 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.30.70.250 663 724 2.0E-6 T 06-07-2017 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.30.70.250 2692 2752 2.3E-6 T 06-07-2017 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SMART SM00829 1367 1669 3.4E-190 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF52151 2753 2852 2.07E-74 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF52151 2570 2692 2.07E-74 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF47336 1957 2069 4.71E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1386 1443 1.7E-4 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3676 3691 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF08990 Erythronolide synthase docking 3 25 1.3E-11 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF53474 3679 3717 2.39E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF53474 3778 4023 2.39E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:1.10.1200.10 3647 3722 3.5E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:1.10.1200.10 1961 2034 2.3E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.40.366.10 725 845 1.8E-81 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.40.366.10 2753 2873 2.7E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.40.366.10 2567 2687 2.7E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Gene3D G3DSA:3.40.366.10 539 659 1.8E-81 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 SUPERFAMILY SSF51735 1466 1604 5.74E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 278 2.8E-84 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32325 93a195031f10d73a7ba709fa3ba127ee 4028 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2054 2304 2.4E-89 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS07085 028fa9ab094b81ae3e558170e17227e5 295 SUPERFAMILY SSF55447 172 284 3.01E-19 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMD11_RS07085 028fa9ab094b81ae3e558170e17227e5 295 Gene3D G3DSA:3.30.43.10 2 51 1.5E-14 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS07085 028fa9ab094b81ae3e558170e17227e5 295 Gene3D G3DSA:3.30.390.50 172 283 1.0E-31 T 06-07-2017 SMD11_RS07085 028fa9ab094b81ae3e558170e17227e5 295 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 2 164 8.5E-45 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMD11_RS07085 028fa9ab094b81ae3e558170e17227e5 295 SMART SM01092 171 281 5.8E-19 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMD11_RS07085 028fa9ab094b81ae3e558170e17227e5 295 Gene3D G3DSA:3.30.465.10 53 164 5.4E-33 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS07085 028fa9ab094b81ae3e558170e17227e5 295 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 173 279 2.5E-10 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMD11_RS07085 028fa9ab094b81ae3e558170e17227e5 295 SUPERFAMILY SSF56176 2 164 7.48E-49 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 Gene3D G3DSA:3.30.30.30 39 99 1.9E-16 T 06-07-2017 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 611 36.296 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 SUPERFAMILY SSF53067 161 353 1.36E-65 T 06-07-2017 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 Gene3D G3DSA:2.60.34.10 361 503 3.2E-72 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 SUPERFAMILY SSF100920 355 511 2.35E-59 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 Gene3D G3DSA:3.30.420.40 289 331 7.9E-34 T 06-07-2017 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 Gene3D G3DSA:3.30.420.40 169 199 7.9E-34 T 06-07-2017 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 Gene3D G3DSA:3.90.640.10 200 285 1.0E-31 T 06-07-2017 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 SUPERFAMILY SSF100934 505 576 9.81E-5 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 PRINTS PR00301 70kDa heat shock protein signature 440 456 4.0E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 PRINTS PR00301 70kDa heat shock protein signature 336 356 4.0E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 PRINTS PR00301 70kDa heat shock protein signature 31 43 4.0E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 PRINTS PR00301 70kDa heat shock protein signature 304 320 4.0E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 PRINTS PR00301 70kDa heat shock protein signature 359 378 4.0E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 PRINTS PR00301 70kDa heat shock protein signature 3 16 4.0E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 PRINTS PR00301 70kDa heat shock protein signature 54 62 4.0E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 PRINTS PR00301 70kDa heat shock protein signature 114 134 4.0E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 PRINTS PR00301 70kDa heat shock protein signature 172 182 4.0E-74 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 Pfam PF00012 Hsp70 protein 4 574 8.8E-246 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 SUPERFAMILY SSF53067 4 160 1.87E-57 T 06-07-2017 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 Gene3D G3DSA:3.30.420.40 100 168 1.2E-55 T 06-07-2017 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 Gene3D G3DSA:3.30.420.40 4 38 1.2E-55 T 06-07-2017 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 Gene3D G3DSA:1.20.1270.10 504 574 4.0E-28 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 SMD11_RS17595 df26ba0e6289ccf1661873d020851208 620 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 574 2.1E-279 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 SMD11_RS22395 8a18077a0f1c69ef9f0d0ed20142d594 137 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 136 31.029 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD11_RS22395 8a18077a0f1c69ef9f0d0ed20142d594 137 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 06-07-2017 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD11_RS22395 8a18077a0f1c69ef9f0d0ed20142d594 137 SMART SM00562 2 136 2.9E-71 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD11_RS22395 8a18077a0f1c69ef9f0d0ed20142d594 137 Pfam PF00334 Nucleoside diphosphate kinase 3 134 3.2E-50 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD11_RS22395 8a18077a0f1c69ef9f0d0ed20142d594 137 Gene3D G3DSA:3.30.70.141 2 134 5.2E-53 T 06-07-2017 SMD11_RS22395 8a18077a0f1c69ef9f0d0ed20142d594 137 SUPERFAMILY SSF54919 2 135 3.14E-50 T 06-07-2017 SMD11_RS22395 8a18077a0f1c69ef9f0d0ed20142d594 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 3.6E-41 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD11_RS22395 8a18077a0f1c69ef9f0d0ed20142d594 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 3.6E-41 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD11_RS22395 8a18077a0f1c69ef9f0d0ed20142d594 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 3.6E-41 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD11_RS22395 8a18077a0f1c69ef9f0d0ed20142d594 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 3.6E-41 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD11_RS22395 8a18077a0f1c69ef9f0d0ed20142d594 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 3.6E-41 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 SMART SM00760 562 631 1.7E-34 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 381 395 6.7E-52 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 413 427 6.7E-52 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 447 474 6.7E-52 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 612 631 6.7E-52 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 349 369 6.7E-52 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 ProSitePatterns PS01008 DnaA protein signature. 612 631 - T 06-07-2017 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 Gene3D G3DSA:3.40.50.300 313 480 1.6E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 565 631 4.6E-29 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 Pfam PF00308 Bacterial dnaA protein 316 533 8.3E-104 T 06-07-2017 IPR013317 Chromosomal replication initiator protein DnaA SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 Gene3D G3DSA:1.10.8.60 482 551 2.1E-28 T 06-07-2017 SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 9 653 33.226 T 06-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 274 652 6.5E-149 T 06-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 SUPERFAMILY SSF48295 559 654 9.94E-34 T 06-07-2017 IPR010921 Trp repressor/replication initiator GO:0043565 SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 Gene3D G3DSA:1.10.1750.10 557 654 1.1E-37 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 SMART SM00382 348 476 2.2E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS16905 68d7f13333bbabb04d7573f3f7dac754 655 SUPERFAMILY SSF52540 315 527 1.13E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 PRINTS PR00359 B-class P450 signature 351 362 2.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 PRINTS PR00359 B-class P450 signature 320 335 2.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 PRINTS PR00359 B-class P450 signature 154 169 2.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 PRINTS PR00359 B-class P450 signature 90 101 2.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 PRINTS PR00359 B-class P450 signature 192 214 2.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 PRINTS PR00359 B-class P450 signature 292 319 2.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 PRINTS PR00359 B-class P450 signature 137 153 2.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 PRINTS PR00359 B-class P450 signature 273 284 2.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 PRINTS PR00359 B-class P450 signature 342 351 2.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 Pfam PF00067 Cytochrome P450 173 265 2.0E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 Pfam PF00067 Cytochrome P450 270 372 7.7E-19 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 Gene3D G3DSA:1.10.630.10 11 402 2.4E-115 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 SUPERFAMILY SSF48264 17 402 4.19E-89 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 PRINTS PR00385 P450 superfamily signature 342 351 5.7E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 PRINTS PR00385 P450 superfamily signature 351 362 5.7E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 PRINTS PR00385 P450 superfamily signature 273 284 5.7E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS15090 8355698ac49cf0f923827a0c846434f3 402 PRINTS PR00385 P450 superfamily signature 238 255 5.7E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS15675 5d9ea0e1275c96ac0e583a91e2a58c1a 259 SUPERFAMILY SSF54593 7 122 4.3E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS15675 5d9ea0e1275c96ac0e583a91e2a58c1a 259 Pfam PF02311 AraC-like ligand binding domain 182 229 3.9E-5 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD11_RS15675 5d9ea0e1275c96ac0e583a91e2a58c1a 259 SUPERFAMILY SSF51182 136 238 5.01E-13 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS15675 5d9ea0e1275c96ac0e583a91e2a58c1a 259 Gene3D G3DSA:3.10.180.10 3 123 3.7E-26 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS15675 5d9ea0e1275c96ac0e583a91e2a58c1a 259 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 120 4.5E-7 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS15675 5d9ea0e1275c96ac0e583a91e2a58c1a 259 Gene3D G3DSA:2.60.120.10 156 235 3.5E-12 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS05010 b385dc3b9136c0a4f1c67ab043d89a91 218 Pfam PF02080 TrkA-C domain 151 215 1.4E-10 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD11_RS05010 b385dc3b9136c0a4f1c67ab043d89a91 218 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 4.3E-15 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS05010 b385dc3b9136c0a4f1c67ab043d89a91 218 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 4.3E-15 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS05010 b385dc3b9136c0a4f1c67ab043d89a91 218 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 4.3E-15 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS05010 b385dc3b9136c0a4f1c67ab043d89a91 218 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 4.3E-15 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS05010 b385dc3b9136c0a4f1c67ab043d89a91 218 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 4.3E-15 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS05010 b385dc3b9136c0a4f1c67ab043d89a91 218 Gene3D G3DSA:3.40.50.720 1 128 9.5E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05010 b385dc3b9136c0a4f1c67ab043d89a91 218 Pfam PF02254 TrkA-N domain 3 117 3.0E-27 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SMD11_RS05010 b385dc3b9136c0a4f1c67ab043d89a91 218 Gene3D G3DSA:3.30.70.1450 150 207 3.9E-6 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD11_RS05010 b385dc3b9136c0a4f1c67ab043d89a91 218 SUPERFAMILY SSF116726 143 213 1.83E-10 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD11_RS05010 b385dc3b9136c0a4f1c67ab043d89a91 218 SUPERFAMILY SSF51735 1 140 1.93E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS01470 ddb7b2bd9cde4f6abb3dee9a44ea1a22 473 Gene3D G3DSA:1.20.1250.20 245 451 3.5E-13 T 06-07-2017 SMD11_RS01470 ddb7b2bd9cde4f6abb3dee9a44ea1a22 473 Gene3D G3DSA:1.20.1250.20 2 175 7.1E-29 T 06-07-2017 SMD11_RS01470 ddb7b2bd9cde4f6abb3dee9a44ea1a22 473 SUPERFAMILY SSF103473 2 174 4.19E-51 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS01470 ddb7b2bd9cde4f6abb3dee9a44ea1a22 473 SUPERFAMILY SSF103473 227 445 4.19E-51 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS01470 ddb7b2bd9cde4f6abb3dee9a44ea1a22 473 Pfam PF07690 Major Facilitator Superfamily 2 388 2.9E-46 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS34565 2863cd0becd5acb0e86861ee03c011df 415 Pfam PF00005 ABC transporter 182 334 1.2E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS34565 2863cd0becd5acb0e86861ee03c011df 415 Gene3D G3DSA:3.40.50.300 164 394 5.3E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS34565 2863cd0becd5acb0e86861ee03c011df 415 ProSitePatterns PS00211 ABC transporters family signature. 306 320 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS34565 2863cd0becd5acb0e86861ee03c011df 415 SUPERFAMILY SSF52540 158 405 2.56E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS34565 2863cd0becd5acb0e86861ee03c011df 415 SMART SM00382 190 380 7.7E-20 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS03775 49aa7bf59896f42324266c4d61956de2 904 Gene3D G3DSA:3.40.50.300 599 823 1.6E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03775 49aa7bf59896f42324266c4d61956de2 904 Gene3D G3DSA:2.60.120.260 429 548 1.5E-20 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS03775 49aa7bf59896f42324266c4d61956de2 904 Gene3D G3DSA:3.40.50.1820 59 197 1.2E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS03775 49aa7bf59896f42324266c4d61956de2 904 Gene3D G3DSA:3.40.50.1820 235 343 1.2E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS03775 49aa7bf59896f42324266c4d61956de2 904 SUPERFAMILY SSF49785 377 553 2.34E-23 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS03775 49aa7bf59896f42324266c4d61956de2 904 ProSitePatterns PS00211 ABC transporters family signature. 735 749 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS03775 49aa7bf59896f42324266c4d61956de2 904 SMART SM00939 335 553 6.7E-23 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMD11_RS03775 49aa7bf59896f42324266c4d61956de2 904 SUPERFAMILY SSF52540 595 826 2.17E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03775 49aa7bf59896f42324266c4d61956de2 904 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 73 291 8.9E-19 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SMD11_RS03775 49aa7bf59896f42324266c4d61956de2 904 Pfam PF00005 ABC transporter 623 763 8.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS03775 49aa7bf59896f42324266c4d61956de2 904 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 434 537 8.3E-12 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMD11_RS03775 49aa7bf59896f42324266c4d61956de2 904 SMART SM00382 631 811 9.3E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS03775 49aa7bf59896f42324266c4d61956de2 904 SUPERFAMILY SSF53474 238 347 3.03E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS03775 49aa7bf59896f42324266c4d61956de2 904 SUPERFAMILY SSF53474 60 193 3.03E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS25440 617e39ce779e1277fafe7795d955a147 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 249 7.8E-40 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS25440 617e39ce779e1277fafe7795d955a147 263 SUPERFAMILY SSF52096 7 255 1.02E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS25440 617e39ce779e1277fafe7795d955a147 263 Gene3D G3DSA:3.90.226.10 10 255 8.2E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS25440 617e39ce779e1277fafe7795d955a147 263 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 119 139 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMD11_RS14145 3780a421f8af140817908c2ec6f1bfb4 168 Gene3D G3DSA:3.30.1330.50 13 165 2.2E-54 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMD11_RS14145 3780a421f8af140817908c2ec6f1bfb4 168 SUPERFAMILY SSF69765 13 164 7.19E-49 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMD11_RS14145 3780a421f8af140817908c2ec6f1bfb4 168 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 14 164 1.9E-45 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMD11_RS14145 3780a421f8af140817908c2ec6f1bfb4 168 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 47 62 - T 06-07-2017 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMD11_RS14145 3780a421f8af140817908c2ec6f1bfb4 168 Pfam PF02542 YgbB family 14 163 6.6E-46 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMD11_RS14145 3780a421f8af140817908c2ec6f1bfb4 168 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 12 165 30.458 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 SMD11_RS13950 4fa4089158522ff5305922688ec4a873 425 Gene3D G3DSA:3.40.190.10 167 348 4.0E-28 T 06-07-2017 SMD11_RS13950 4fa4089158522ff5305922688ec4a873 425 Pfam PF13416 Bacterial extracellular solute-binding protein 58 354 7.7E-35 T 06-07-2017 SMD11_RS13950 4fa4089158522ff5305922688ec4a873 425 SUPERFAMILY SSF53850 48 417 3.15E-57 T 06-07-2017 SMD11_RS13950 4fa4089158522ff5305922688ec4a873 425 Gene3D G3DSA:3.40.190.10 51 166 1.1E-17 T 06-07-2017 SMD11_RS18920 b6254d72061b8e448f4f64fc5d301853 139 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 06-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18920 b6254d72061b8e448f4f64fc5d301853 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.857 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18920 b6254d72061b8e448f4f64fc5d301853 139 Gene3D G3DSA:3.90.1170.10 23 136 5.3E-52 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SMD11_RS18920 b6254d72061b8e448f4f64fc5d301853 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 4.8E-54 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18920 b6254d72061b8e448f4f64fc5d301853 139 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.5E-46 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SMD11_RS18920 b6254d72061b8e448f4f64fc5d301853 139 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 06-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18920 b6254d72061b8e448f4f64fc5d301853 139 PRINTS PR00060 Ribosomal protein L16 signature 58 87 7.8E-38 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18920 b6254d72061b8e448f4f64fc5d301853 139 PRINTS PR00060 Ribosomal protein L16 signature 88 117 7.8E-38 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18920 b6254d72061b8e448f4f64fc5d301853 139 PRINTS PR00060 Ribosomal protein L16 signature 24 36 7.8E-38 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18920 b6254d72061b8e448f4f64fc5d301853 139 PRINTS PR00060 Ribosomal protein L16 signature 42 53 7.8E-38 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18920 b6254d72061b8e448f4f64fc5d301853 139 SUPERFAMILY SSF54686 1 135 1.01E-54 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 Pfam PF00931 NB-ARC domain 305 542 4.5E-10 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SMART SM00028 963 996 160.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SMART SM00028 1003 1036 0.043 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SMART SM00028 186 219 95.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SMART SM00028 843 876 11.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SMART SM00028 1043 1076 80.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SMART SM00028 923 956 12.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SMART SM00028 763 796 26.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SMART SM00028 723 756 16.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 Pfam PF03704 Bacterial transcriptional activator domain 91 236 5.0E-40 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SMART SM00862 7 84 7.4E-13 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 Gene3D G3DSA:3.40.50.300 296 417 2.7E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SMART SM00382 299 437 0.0017 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SUPERFAMILY SSF46894 11 84 3.12E-13 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SUPERFAMILY SSF48452 86 253 3.25E-34 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SMART SM01043 91 236 1.5E-43 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 Gene3D G3DSA:1.25.40.10 831 1075 8.2E-22 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 Pfam PF00486 Transcriptional regulatory protein, C terminal 10 84 9.0E-10 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 Gene3D G3DSA:1.10.10.10 2 86 1.2E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SUPERFAMILY SSF48452 963 1076 3.48E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 PRINTS PR00364 Disease resistance protein signature 302 317 4.7E-8 T 06-07-2017 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 PRINTS PR00364 Disease resistance protein signature 380 394 4.7E-8 T 06-07-2017 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 PRINTS PR00364 Disease resistance protein signature 468 482 4.7E-8 T 06-07-2017 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 Pfam PF13424 Tetratricopeptide repeat 723 794 1.1E-10 T 06-07-2017 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 Pfam PF13181 Tetratricopeptide repeat 1004 1035 0.14 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SUPERFAMILY SSF52540 263 536 1.49E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SUPERFAMILY SSF48452 719 833 4.17E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 SUPERFAMILY SSF48452 837 997 2.91E-15 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 Gene3D G3DSA:1.25.40.10 679 830 5.0E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS02525 329f130044e7231d4f8ea99d1e2c089b 1090 Gene3D G3DSA:1.25.40.10 98 212 5.0E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS00940 eb2c70fe93e0e3225fb8992a04818a55 318 SUPERFAMILY SSF46785 5 88 9.99E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00940 eb2c70fe93e0e3225fb8992a04818a55 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.1E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS00940 eb2c70fe93e0e3225fb8992a04818a55 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.1E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS00940 eb2c70fe93e0e3225fb8992a04818a55 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.1E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS00940 eb2c70fe93e0e3225fb8992a04818a55 318 Gene3D G3DSA:3.40.190.10 177 266 1.9E-16 T 06-07-2017 SMD11_RS00940 eb2c70fe93e0e3225fb8992a04818a55 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 7.8E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS00940 eb2c70fe93e0e3225fb8992a04818a55 318 Pfam PF03466 LysR substrate binding domain 88 293 5.9E-29 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS00940 eb2c70fe93e0e3225fb8992a04818a55 318 Gene3D G3DSA:3.40.190.10 90 176 8.8E-16 T 06-07-2017 SMD11_RS00940 eb2c70fe93e0e3225fb8992a04818a55 318 SUPERFAMILY SSF53850 89 295 8.69E-25 T 06-07-2017 SMD11_RS00940 eb2c70fe93e0e3225fb8992a04818a55 318 Gene3D G3DSA:1.10.10.10 4 87 1.3E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS34420 be76acbf01a427dcfb5fd11f44b4e436 371 Gene3D G3DSA:1.25.40.10 168 289 2.4E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS34420 be76acbf01a427dcfb5fd11f44b4e436 371 SUPERFAMILY SSF48452 183 294 8.68E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS34420 be76acbf01a427dcfb5fd11f44b4e436 371 Gene3D G3DSA:1.10.260.40 13 57 1.6E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS21040 da85e2e61a4e3b225ff5e53b9cc99108 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 276 2.4E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21040 da85e2e61a4e3b225ff5e53b9cc99108 285 Gene3D G3DSA:1.10.3720.10 7 273 1.3E-64 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21040 da85e2e61a4e3b225ff5e53b9cc99108 285 SUPERFAMILY SSF161098 7 279 2.24E-67 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS12710 2836e7894d9db21a5778ee135142b61b 228 Pfam PF00072 Response regulator receiver domain 8 115 3.0E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS12710 2836e7894d9db21a5778ee135142b61b 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 1.2E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS12710 2836e7894d9db21a5778ee135142b61b 228 SUPERFAMILY SSF52172 7 175 2.2E-41 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS12710 2836e7894d9db21a5778ee135142b61b 228 SMART SM00448 5 115 2.2E-40 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS12710 2836e7894d9db21a5778ee135142b61b 228 SMART SM00862 148 224 1.0E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS12710 2836e7894d9db21a5778ee135142b61b 228 Gene3D G3DSA:1.10.10.10 127 226 1.2E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12710 2836e7894d9db21a5778ee135142b61b 228 Gene3D G3DSA:3.40.50.2300 7 126 6.8E-41 T 06-07-2017 SMD11_RS10175 e95e60d659646f2a740a3a08bec83571 1203 SUPERFAMILY SSF52540 313 545 1.5E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10175 e95e60d659646f2a740a3a08bec83571 1203 Pfam PF04851 Type III restriction enzyme, res subunit 324 508 1.8E-19 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SMD11_RS10175 e95e60d659646f2a740a3a08bec83571 1203 SMART SM00487 315 544 8.0E-8 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS10175 e95e60d659646f2a740a3a08bec83571 1203 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 5 237 1.4E-23 T 06-07-2017 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 SMD11_RS10175 e95e60d659646f2a740a3a08bec83571 1203 Gene3D G3DSA:3.40.50.300 340 511 9.4E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24495 0b40eb87b4faef2a30847c81aea5946e 473 Gene3D G3DSA:3.40.1190.10 84 312 1.5E-70 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS24495 0b40eb87b4faef2a30847c81aea5946e 473 Gene3D G3DSA:3.90.190.20 319 466 5.1E-43 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS24495 0b40eb87b4faef2a30847c81aea5946e 473 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 465 32.307 T 06-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS24495 0b40eb87b4faef2a30847c81aea5946e 473 SUPERFAMILY SSF53623 103 313 2.22E-55 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS24495 0b40eb87b4faef2a30847c81aea5946e 473 Gene3D G3DSA:3.40.1390.10 3 81 4.0E-22 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMD11_RS24495 0b40eb87b4faef2a30847c81aea5946e 473 Pfam PF02875 Mur ligase family, glutamate ligase domain 321 406 1.4E-19 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS24495 0b40eb87b4faef2a30847c81aea5946e 473 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 33 464 2.6E-130 T 06-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS24495 0b40eb87b4faef2a30847c81aea5946e 473 Pfam PF08245 Mur ligase middle domain 108 297 8.9E-46 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS24495 0b40eb87b4faef2a30847c81aea5946e 473 SUPERFAMILY SSF53244 320 464 4.58E-35 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS24495 0b40eb87b4faef2a30847c81aea5946e 473 Pfam PF01225 Mur ligase family, catalytic domain 31 94 3.6E-12 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMD11_RS24495 0b40eb87b4faef2a30847c81aea5946e 473 SUPERFAMILY SSF63418 4 98 5.36E-22 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMD11_RS07525 0c396f794935b31451f30b4267d7176b 645 Pfam PF02780 Transketolase, C-terminal domain 501 614 5.1E-29 T 06-07-2017 IPR033248 Transketolase, C-terminal domain SMD11_RS07525 0c396f794935b31451f30b4267d7176b 645 Gene3D G3DSA:3.40.50.920 502 621 4.2E-31 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS07525 0c396f794935b31451f30b4267d7176b 645 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 279 4.1E-108 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS07525 0c396f794935b31451f30b4267d7176b 645 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS07525 0c396f794935b31451f30b4267d7176b 645 SMART SM00861 315 479 3.0E-51 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS07525 0c396f794935b31451f30b4267d7176b 645 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS07525 0c396f794935b31451f30b4267d7176b 645 Pfam PF02779 Transketolase, pyrimidine binding domain 315 477 1.4E-36 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS07525 0c396f794935b31451f30b4267d7176b 645 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 623 41.693 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS07525 0c396f794935b31451f30b4267d7176b 645 SUPERFAMILY SSF52518 295 477 2.75E-51 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS07525 0c396f794935b31451f30b4267d7176b 645 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 5 619 3.2E-189 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS07525 0c396f794935b31451f30b4267d7176b 645 Gene3D G3DSA:3.40.50.970 19 194 1.0E-62 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS07525 0c396f794935b31451f30b4267d7176b 645 Gene3D G3DSA:3.40.50.970 239 330 1.0E-62 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS07525 0c396f794935b31451f30b4267d7176b 645 SUPERFAMILY SSF52922 499 621 2.36E-27 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS07525 0c396f794935b31451f30b4267d7176b 645 Gene3D G3DSA:3.40.50.970 331 479 1.2E-30 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS07525 0c396f794935b31451f30b4267d7176b 645 SUPERFAMILY SSF52518 3 345 6.68E-71 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 356 429 2.3E-28 T 06-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 Pfam PF09269 Domain of unknown function (DUF1967) 356 428 1.4E-25 T 06-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 Gene3D G3DSA:2.70.210.12 3 156 1.0E-47 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 SUPERFAMILY SSF102741 354 430 2.88E-21 T 06-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 SUPERFAMILY SSF52540 161 339 1.56E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 06-07-2017 IPR006074 GTP1/OBG, conserved site GO:0005525 SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 Pfam PF01926 50S ribosome-binding GTPase 161 283 1.3E-22 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 Gene3D G3DSA:3.40.50.300 160 343 2.5E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 326 9.5E-124 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 3.9E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 3.9E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 3.9E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 3.9E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 Hamap MF_01454 GTPase Obg [obg]. 3 330 43.656 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 SUPERFAMILY SSF82051 4 157 3.14E-46 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 SMD11_RS22455 4493a000326e631a11667095c010ea3a 478 Pfam PF01018 GTP1/OBG 4 157 2.6E-51 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 SMD11_RS04510 5cf5910055b9590be44cac90736ee717 466 SMART SM00530 9 64 5.2E-14 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS04510 5cf5910055b9590be44cac90736ee717 466 Pfam PF06114 Domain of unknown function (DUF955) 193 305 8.0E-21 T 06-07-2017 IPR010359 HTH domain, IrrE-type SMD11_RS04510 5cf5910055b9590be44cac90736ee717 466 PIRSF PIRSF019251 1 466 5.3E-199 T 06-07-2017 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 SMD11_RS04510 5cf5910055b9590be44cac90736ee717 466 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 306 462 6.5E-71 T 06-07-2017 IPR018653 Domain of unknown function DUF2083,transcriptional regulator SMD11_RS04510 5cf5910055b9590be44cac90736ee717 466 Pfam PF13560 Helix-turn-helix domain 7 60 4.9E-13 T 06-07-2017 SMD11_RS04510 5cf5910055b9590be44cac90736ee717 466 SUPERFAMILY SSF47413 4 67 3.1E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS04510 5cf5910055b9590be44cac90736ee717 466 Gene3D G3DSA:1.10.260.40 4 85 1.2E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS32285 73ebb97938be694e485b259b6d4685a5 847 Gene3D G3DSA:1.10.10.10 87 140 2.2E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32285 73ebb97938be694e485b259b6d4685a5 847 Gene3D G3DSA:3.30.450.20 342 432 4.7E-4 T 06-07-2017 SMD11_RS32285 73ebb97938be694e485b259b6d4685a5 847 SUPERFAMILY SSF81606 653 842 2.22E-6 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS32285 73ebb97938be694e485b259b6d4685a5 847 SUPERFAMILY SSF55781 191 328 1.14E-7 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS32285 73ebb97938be694e485b259b6d4685a5 847 Gene3D G3DSA:3.30.450.20 465 588 1.0E-14 T 06-07-2017 SMD11_RS32285 73ebb97938be694e485b259b6d4685a5 847 SUPERFAMILY SSF55785 497 590 1.66E-9 T 06-07-2017 IPR000014 PAS domain SMD11_RS32285 73ebb97938be694e485b259b6d4685a5 847 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 665 845 1.3E-41 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS32285 73ebb97938be694e485b259b6d4685a5 847 Gene3D G3DSA:3.30.450.40 189 310 2.2E-5 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS32285 73ebb97938be694e485b259b6d4685a5 847 SMART SM00331 638 846 7.1E-27 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS32285 73ebb97938be694e485b259b6d4685a5 847 Pfam PF08447 PAS fold 497 582 2.5E-6 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 SMD11_RS32285 73ebb97938be694e485b259b6d4685a5 847 SMART SM01012 81 136 4.0E-7 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 SMD11_RS32285 73ebb97938be694e485b259b6d4685a5 847 Pfam PF03861 ANTAR domain 85 136 1.1E-7 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 SMD11_RS22400 245cd7b9f3dbef91e20729023c6f0c91 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 43 61 4.4E-62 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS22400 245cd7b9f3dbef91e20729023c6f0c91 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 294 320 4.4E-62 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS22400 245cd7b9f3dbef91e20729023c6f0c91 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 181 201 4.4E-62 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS22400 245cd7b9f3dbef91e20729023c6f0c91 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 63 86 4.4E-62 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS22400 245cd7b9f3dbef91e20729023c6f0c91 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 126 145 4.4E-62 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS22400 245cd7b9f3dbef91e20729023c6f0c91 339 Gene3D G3DSA:3.30.420.40 154 180 9.1E-36 T 06-07-2017 SMD11_RS22400 245cd7b9f3dbef91e20729023c6f0c91 339 Gene3D G3DSA:3.30.420.40 257 311 9.1E-36 T 06-07-2017 SMD11_RS22400 245cd7b9f3dbef91e20729023c6f0c91 339 Gene3D G3DSA:3.90.640.10 181 253 4.3E-32 T 06-07-2017 SMD11_RS22400 245cd7b9f3dbef91e20729023c6f0c91 339 SUPERFAMILY SSF53067 144 322 1.23E-51 T 06-07-2017 SMD11_RS22400 245cd7b9f3dbef91e20729023c6f0c91 339 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 6 330 8.5E-154 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS22400 245cd7b9f3dbef91e20729023c6f0c91 339 Gene3D G3DSA:3.30.420.40 6 153 3.7E-48 T 06-07-2017 SMD11_RS22400 245cd7b9f3dbef91e20729023c6f0c91 339 Pfam PF06723 MreB/Mbl protein 6 330 2.8E-156 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS22400 245cd7b9f3dbef91e20729023c6f0c91 339 SUPERFAMILY SSF53067 5 142 1.01E-42 T 06-07-2017 SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 262 274 - T 06-07-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 12 477 3.8E-202 T 06-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 SUPERFAMILY SSF48179 185 480 3.68E-115 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 Gene3D G3DSA:1.10.1040.10 189 443 1.7E-102 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 Gene3D G3DSA:3.40.50.720 6 188 2.0E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 187 476 2.6E-119 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 SMART SM01350 187 477 6.9E-196 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 11 34 3.2E-78 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 366 388 3.2E-78 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 127 152 3.2E-78 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 176 204 3.2E-78 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 74 103 3.2E-78 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 258 285 3.2E-78 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 SUPERFAMILY SSF51735 11 181 3.75E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 12 182 9.3E-52 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 PIRSF PIRSF000109 6 485 1.4E-197 T 06-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS03100 1de12ebb44610f2ca6b044ae9a625f7f 486 Gene3D G3DSA:1.20.5.320 445 482 1.5E-19 T 06-07-2017 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS19350 e03605b7c398ee34ec602ea994ff1a8d 355 Gene3D G3DSA:3.40.50.720 178 289 6.4E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19350 e03605b7c398ee34ec602ea994ff1a8d 355 Pfam PF00107 Zinc-binding dehydrogenase 185 308 2.3E-22 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS19350 e03605b7c398ee34ec602ea994ff1a8d 355 Gene3D G3DSA:3.90.180.10 1 177 2.8E-56 T 06-07-2017 IPR011032 GroES-like SMD11_RS19350 e03605b7c398ee34ec602ea994ff1a8d 355 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 142 4.2E-26 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS19350 e03605b7c398ee34ec602ea994ff1a8d 355 SUPERFAMILY SSF51735 147 319 2.24E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19350 e03605b7c398ee34ec602ea994ff1a8d 355 SUPERFAMILY SSF50129 7 179 1.29E-50 T 06-07-2017 IPR011032 GroES-like SMD11_RS19350 e03605b7c398ee34ec602ea994ff1a8d 355 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD11_RS19350 e03605b7c398ee34ec602ea994ff1a8d 355 SMART SM00829 12 352 1.3E-7 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS09940 1ec30637b8bf9354642ef3203b8c8d60 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 3.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS09940 1ec30637b8bf9354642ef3203b8c8d60 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 3.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS09940 1ec30637b8bf9354642ef3203b8c8d60 210 SUPERFAMILY SSF46689 9 77 2.14E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS09940 1ec30637b8bf9354642ef3203b8c8d60 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 63 5.2E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS09940 1ec30637b8bf9354642ef3203b8c8d60 210 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 62 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD11_RS09940 1ec30637b8bf9354642ef3203b8c8d60 210 Gene3D G3DSA:1.10.357.10 61 191 2.0E-8 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS09940 1ec30637b8bf9354642ef3203b8c8d60 210 Gene3D G3DSA:1.10.10.60 8 60 6.4E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS23275 17371cc7c0f712956aef828f855d5f1f 152 PIRSF PIRSF000239 1 152 2.6E-29 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMD11_RS23275 17371cc7c0f712956aef828f855d5f1f 152 Gene3D G3DSA:3.40.30.10 2 152 1.1E-51 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS23275 17371cc7c0f712956aef828f855d5f1f 152 SUPERFAMILY SSF52833 1 152 1.88E-49 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS23275 17371cc7c0f712956aef828f855d5f1f 152 Pfam PF00578 AhpC/TSA family 5 130 9.5E-41 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMD11_RS28560 16cae589ce7a7a416baaf11cfafecc98 415 Gene3D G3DSA:3.30.470.20 109 346 2.5E-19 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS28560 16cae589ce7a7a416baaf11cfafecc98 415 SUPERFAMILY SSF56059 108 330 1.61E-29 T 06-07-2017 SMD11_RS28560 16cae589ce7a7a416baaf11cfafecc98 415 SMART SM01209 116 294 0.007 T 06-07-2017 SMD11_RS28560 16cae589ce7a7a416baaf11cfafecc98 415 Pfam PF13535 ATP-grasp domain 155 297 1.7E-18 T 06-07-2017 SMD11_RS34040 35e34d6a78f7bde61a1b372910332c26 159 Pfam PF00239 Resolvase, N terminal domain 75 157 2.1E-9 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD11_RS34040 35e34d6a78f7bde61a1b372910332c26 159 SUPERFAMILY SSF53041 75 148 3.66E-9 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD11_RS34040 35e34d6a78f7bde61a1b372910332c26 159 Gene3D G3DSA:3.40.50.1390 75 148 5.6E-10 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD11_RS25505 3fac295661e81f60dd15c710e3fe4ca2 229 Pfam PF07947 YhhN-like protein 33 203 2.6E-32 T 06-07-2017 IPR012506 YhhN-like GO:0016021 SMD11_RS05135 7b93840b479168324273f374768b3157 789 Gene3D G3DSA:3.30.1490.20 7 194 1.3E-59 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS05135 7b93840b479168324273f374768b3157 789 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 476 786 4.2E-60 T 06-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 SMD11_RS05135 7b93840b479168324273f374768b3157 789 SUPERFAMILY SSF51621 462 788 2.59E-90 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS05135 7b93840b479168324273f374768b3157 789 Gene3D G3DSA:3.20.20.60 478 787 1.1E-96 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS05135 7b93840b479168324273f374768b3157 789 SUPERFAMILY SSF56059 4 382 3.41E-96 T 06-07-2017 SMD11_RS05135 7b93840b479168324273f374768b3157 789 SUPERFAMILY SSF52009 345 462 1.57E-29 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD11_RS05135 7b93840b479168324273f374768b3157 789 Pfam PF00391 PEP-utilising enzyme, mobile domain 382 453 8.4E-24 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD11_RS05135 7b93840b479168324273f374768b3157 789 PIRSF PIRSF000854 3 789 0.0 T 06-07-2017 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 SMD11_RS05135 7b93840b479168324273f374768b3157 789 Gene3D G3DSA:3.30.470.20 197 352 9.4E-50 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS05135 7b93840b479168324273f374768b3157 789 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 692 710 - T 06-07-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 SMD11_RS05135 7b93840b479168324273f374768b3157 789 Gene3D G3DSA:3.50.30.10 377 467 3.1E-30 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD11_RS05135 7b93840b479168324273f374768b3157 789 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 339 1.9E-103 T 06-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SMD11_RS05135 7b93840b479168324273f374768b3157 789 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 412 423 - T 06-07-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 SMD11_RS05135 7b93840b479168324273f374768b3157 789 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 788 0.0 T 06-07-2017 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 SMD11_RS23600 4a1c939f5df2c3720d1f77629bb01d25 333 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 167 195 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS23600 4a1c939f5df2c3720d1f77629bb01d25 333 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 168 3.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS23600 4a1c939f5df2c3720d1f77629bb01d25 333 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 100 111 3.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS23600 4a1c939f5df2c3720d1f77629bb01d25 333 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 180 199 3.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS23600 4a1c939f5df2c3720d1f77629bb01d25 333 Gene3D G3DSA:3.40.50.720 4 273 4.8E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS23600 4a1c939f5df2c3720d1f77629bb01d25 333 Pfam PF00106 short chain dehydrogenase 11 219 1.3E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS23600 4a1c939f5df2c3720d1f77629bb01d25 333 SUPERFAMILY SSF51735 6 277 1.24E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS23600 4a1c939f5df2c3720d1f77629bb01d25 333 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.5E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS23600 4a1c939f5df2c3720d1f77629bb01d25 333 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 111 1.5E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS23600 4a1c939f5df2c3720d1f77629bb01d25 333 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 199 1.5E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS23600 4a1c939f5df2c3720d1f77629bb01d25 333 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 170 1.5E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS23600 4a1c939f5df2c3720d1f77629bb01d25 333 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 218 1.5E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS23600 4a1c939f5df2c3720d1f77629bb01d25 333 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 211 1.1E-4 T 06-07-2017 SMD11_RS17920 392b3f1262827ac645f2c8be17987802 226 PIRSF PIRSF001586 1 226 1.3E-83 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD11_RS17920 392b3f1262827ac645f2c8be17987802 226 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 4 222 2.0E-82 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD11_RS17920 392b3f1262827ac645f2c8be17987802 226 SUPERFAMILY SSF52317 3 221 3.75E-69 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS17920 392b3f1262827ac645f2c8be17987802 226 SMART SM01211 2 223 2.3E-122 T 06-07-2017 SMD11_RS17920 392b3f1262827ac645f2c8be17987802 226 Gene3D G3DSA:3.40.50.880 3 221 7.4E-41 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS17920 392b3f1262827ac645f2c8be17987802 226 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 3 221 40.635 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD11_RS17920 392b3f1262827ac645f2c8be17987802 226 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 3 204 1.6E-34 T 06-07-2017 SMD11_RS32895 50397188b01841f7b7e1094b52566728 448 SUPERFAMILY SSF55031 296 331 3.66E-8 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS32895 50397188b01841f7b7e1094b52566728 448 SUPERFAMILY SSF55031 201 247 3.66E-8 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS32895 50397188b01841f7b7e1094b52566728 448 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 77 86 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SMD11_RS32895 50397188b01841f7b7e1094b52566728 448 Gene3D G3DSA:3.40.630.10 382 444 2.8E-61 T 06-07-2017 SMD11_RS32895 50397188b01841f7b7e1094b52566728 448 Gene3D G3DSA:3.40.630.10 16 208 2.8E-61 T 06-07-2017 SMD11_RS32895 50397188b01841f7b7e1094b52566728 448 SUPERFAMILY SSF53187 357 445 1.8E-55 T 06-07-2017 SMD11_RS32895 50397188b01841f7b7e1094b52566728 448 SUPERFAMILY SSF53187 14 198 1.8E-55 T 06-07-2017 SMD11_RS32895 50397188b01841f7b7e1094b52566728 448 Gene3D G3DSA:3.30.70.360 209 252 1.6E-13 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS32895 50397188b01841f7b7e1094b52566728 448 Gene3D G3DSA:3.30.70.360 295 342 1.6E-13 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS32895 50397188b01841f7b7e1094b52566728 448 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 112 151 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SMD11_RS32895 50397188b01841f7b7e1094b52566728 448 Pfam PF07687 Peptidase dimerisation domain 196 339 4.0E-9 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS32895 50397188b01841f7b7e1094b52566728 448 Pfam PF01546 Peptidase family M20/M25/M40 78 444 8.9E-32 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD11_RS08560 a229f1387327973f4525fd3fc39702c9 265 Pfam PF00459 Inositol monophosphatase family 6 229 4.0E-56 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS08560 a229f1387327973f4525fd3fc39702c9 265 Gene3D G3DSA:3.30.540.10 7 154 8.6E-46 T 06-07-2017 SMD11_RS08560 a229f1387327973f4525fd3fc39702c9 265 PRINTS PR01959 SuhB family inositol monophosphatase signature 200 212 1.5E-6 T 06-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 SMD11_RS08560 a229f1387327973f4525fd3fc39702c9 265 PRINTS PR01959 SuhB family inositol monophosphatase signature 107 126 1.5E-6 T 06-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 SMD11_RS08560 a229f1387327973f4525fd3fc39702c9 265 SUPERFAMILY SSF56655 7 257 1.44E-74 T 06-07-2017 SMD11_RS08560 a229f1387327973f4525fd3fc39702c9 265 Gene3D G3DSA:3.40.190.80 155 258 7.4E-32 T 06-07-2017 SMD11_RS08560 a229f1387327973f4525fd3fc39702c9 265 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site SMD11_RS08560 a229f1387327973f4525fd3fc39702c9 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 64 80 8.1E-41 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS08560 a229f1387327973f4525fd3fc39702c9 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 210 234 8.1E-41 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS08560 a229f1387327973f4525fd3fc39702c9 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 62 8.1E-41 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS08560 a229f1387327973f4525fd3fc39702c9 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 8.1E-41 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS08560 a229f1387327973f4525fd3fc39702c9 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 179 200 8.1E-41 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS08560 a229f1387327973f4525fd3fc39702c9 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 8.1E-41 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS08560 a229f1387327973f4525fd3fc39702c9 265 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 213 227 - T 06-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 SMD11_RS24160 aaf4de4faec314593ee71cf92ff34f06 395 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 49 394 6.4E-97 T 06-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 SMD11_RS24160 aaf4de4faec314593ee71cf92ff34f06 395 Hamap MF_00569 Quinolinate synthase A [nadA]. 44 394 56.805 T 06-07-2017 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 SMD11_RS24160 aaf4de4faec314593ee71cf92ff34f06 395 SUPERFAMILY SSF142754 53 394 8.24E-93 T 06-07-2017 SMD11_RS24160 aaf4de4faec314593ee71cf92ff34f06 395 Pfam PF02445 Quinolinate synthetase A protein 55 393 1.5E-105 T 06-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 SMD11_RS27295 14444e3ab6377292c2633e76a8d7ca91 394 ProSitePatterns PS00788 Chorismate synthase signature 2. 136 152 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD11_RS27295 14444e3ab6377292c2633e76a8d7ca91 394 PIRSF PIRSF001456 1 386 4.5E-126 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD11_RS27295 14444e3ab6377292c2633e76a8d7ca91 394 TIGRFAM TIGR00033 aroC: chorismate synthase 4 373 1.1E-138 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD11_RS27295 14444e3ab6377292c2633e76a8d7ca91 394 ProSitePatterns PS00789 Chorismate synthase signature 3. 343 359 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD11_RS27295 14444e3ab6377292c2633e76a8d7ca91 394 Hamap MF_00300 Chorismate synthase [aroC]. 4 376 34.299 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD11_RS27295 14444e3ab6377292c2633e76a8d7ca91 394 SUPERFAMILY SSF103263 3 390 2.22E-137 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD11_RS27295 14444e3ab6377292c2633e76a8d7ca91 394 Gene3D G3DSA:3.60.150.10 4 391 6.9E-154 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD11_RS27295 14444e3ab6377292c2633e76a8d7ca91 394 Pfam PF01264 Chorismate synthase 4 368 5.8E-117 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD11_RS27295 14444e3ab6377292c2633e76a8d7ca91 394 ProSitePatterns PS00787 Chorismate synthase signature 1. 10 25 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SMD11_RS08110 6523eb0e23911f1a917ae2884977c324 390 Pfam PF13546 DDE superfamily endonuclease 40 240 2.4E-28 T 06-07-2017 SMD11_RS34170 b4beba491af3d72a5f6b40608fc3b886 257 SUPERFAMILY SSF46689 51 129 1.12E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS34170 b4beba491af3d72a5f6b40608fc3b886 257 SUPERFAMILY SSF48498 127 232 1.78E-11 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS34170 b4beba491af3d72a5f6b40608fc3b886 257 Gene3D G3DSA:1.10.357.10 51 238 1.5E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS34170 b4beba491af3d72a5f6b40608fc3b886 257 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 82 105 5.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS34170 b4beba491af3d72a5f6b40608fc3b886 257 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 62 75 5.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS34170 b4beba491af3d72a5f6b40608fc3b886 257 Pfam PF00440 Bacterial regulatory proteins, tetR family 62 107 6.1E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS10220 477979c3aa5fade98e064703a64a42ff 389 SUPERFAMILY SSF53383 2 381 2.53E-92 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS10220 477979c3aa5fade98e064703a64a42ff 389 Pfam PF00266 Aminotransferase class-V 3 371 3.2E-62 T 06-07-2017 IPR000192 Aminotransferase class V domain SMD11_RS10220 477979c3aa5fade98e064703a64a42ff 389 Gene3D G3DSA:3.90.1150.10 251 376 5.2E-36 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS10220 477979c3aa5fade98e064703a64a42ff 389 PIRSF PIRSF005572 1 386 1.8E-106 T 06-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SMD11_RS10220 477979c3aa5fade98e064703a64a42ff 389 Gene3D G3DSA:3.40.640.10 15 250 1.0E-69 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS06895 1a5880fe839e5020475fe08ce246c2de 184 Gene3D G3DSA:3.40.630.30 9 184 1.5E-28 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS06895 1a5880fe839e5020475fe08ce246c2de 184 SUPERFAMILY SSF55729 70 184 1.58E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS06895 1a5880fe839e5020475fe08ce246c2de 184 SUPERFAMILY SSF55729 6 30 1.58E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS06895 1a5880fe839e5020475fe08ce246c2de 184 Pfam PF00583 Acetyltransferase (GNAT) family 81 157 1.8E-14 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS15360 b2a058e99243fde6d2901e93807ed167 413 Gene3D G3DSA:3.20.20.370 162 379 6.3E-7 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS15360 b2a058e99243fde6d2901e93807ed167 413 SUPERFAMILY SSF88713 100 118 7.79E-20 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS15360 b2a058e99243fde6d2901e93807ed167 413 SUPERFAMILY SSF88713 148 379 7.79E-20 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS10645 d1542ef2048532c2cc50f70297db596f 158 Gene3D G3DSA:1.10.10.10 4 153 3.9E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS10645 d1542ef2048532c2cc50f70297db596f 158 Pfam PF12802 MarR family 40 100 1.3E-11 T 06-07-2017 SMD11_RS10645 d1542ef2048532c2cc50f70297db596f 158 SMART SM00347 34 137 5.5E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS10645 d1542ef2048532c2cc50f70297db596f 158 SUPERFAMILY SSF46785 7 151 1.67E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 SUPERFAMILY SSF48452 368 538 4.09E-36 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 Pfam PF00486 Transcriptional regulatory protein, C terminal 296 364 2.0E-7 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 80 8.9E-7 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 SMART SM01043 102 237 5.7E-16 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 SMART SM01043 371 515 2.3E-56 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 SUPERFAMILY SSF52540 544 804 1.32E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 SUPERFAMILY SSF48452 1025 1231 8.35E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 Gene3D G3DSA:1.10.10.10 25 98 6.6E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 Gene3D G3DSA:1.10.10.10 288 365 5.7E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 PRINTS PR00364 Disease resistance protein signature 738 752 9.7E-11 T 06-07-2017 SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 PRINTS PR00364 Disease resistance protein signature 653 667 9.7E-11 T 06-07-2017 SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 PRINTS PR00364 Disease resistance protein signature 576 591 9.7E-11 T 06-07-2017 SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 SUPERFAMILY SSF46894 277 364 1.81E-11 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 Gene3D G3DSA:1.25.40.10 378 508 2.1E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 Gene3D G3DSA:1.25.40.10 1042 1232 2.1E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 Pfam PF00931 NB-ARC domain 559 756 2.0E-12 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 SUPERFAMILY SSF48452 101 235 3.8E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 Pfam PF03704 Bacterial transcriptional activator domain 372 515 8.0E-47 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 Pfam PF03704 Bacterial transcriptional activator domain 102 220 5.3E-22 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 Gene3D G3DSA:3.40.50.300 571 666 4.0E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 SMART SM00862 15 97 1.1E-7 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 SMART SM00862 290 364 5.9E-11 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS05805 9b853e035d0adf9c8fee64dac6f58c53 1255 SUPERFAMILY SSF46894 7 97 1.76E-10 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS29660 b21bce1583481966b96e10a158b6f268 338 SUPERFAMILY SSF46785 14 93 2.83E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS29660 b21bce1583481966b96e10a158b6f268 338 Pfam PF00891 O-methyltransferase 104 315 4.2E-43 T 06-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 SMD11_RS29660 b21bce1583481966b96e10a158b6f268 338 SUPERFAMILY SSF53335 96 333 8.18E-48 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29660 b21bce1583481966b96e10a158b6f268 338 Gene3D G3DSA:1.10.10.10 12 97 2.5E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS29660 b21bce1583481966b96e10a158b6f268 338 Gene3D G3DSA:3.40.50.150 98 335 3.9E-67 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29660 b21bce1583481966b96e10a158b6f268 338 PIRSF PIRSF005739 2 336 8.6E-51 T 06-07-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 SMD11_RS08575 ca373f370cf8ceb183d6fd2c9154cca5 443 PIRSF PIRSF000136 6 443 3.6E-111 T 06-07-2017 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 SMD11_RS08575 ca373f370cf8ceb183d6fd2c9154cca5 443 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 27 60 - T 06-07-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 SMD11_RS08575 ca373f370cf8ceb183d6fd2c9154cca5 443 Gene3D G3DSA:3.30.43.10 13 83 3.1E-22 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS08575 ca373f370cf8ceb183d6fd2c9154cca5 443 Pfam PF04030 D-arabinono-1,4-lactone oxidase 187 440 1.8E-74 T 06-07-2017 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 SMD11_RS08575 ca373f370cf8ceb183d6fd2c9154cca5 443 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 16 442 3.0E-121 T 06-07-2017 SMD11_RS08575 ca373f370cf8ceb183d6fd2c9154cca5 443 Gene3D G3DSA:3.30.465.10 84 192 2.4E-30 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS08575 ca373f370cf8ceb183d6fd2c9154cca5 443 Pfam PF01565 FAD binding domain 27 162 6.0E-29 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD11_RS08575 ca373f370cf8ceb183d6fd2c9154cca5 443 SUPERFAMILY SSF56176 11 192 2.72E-45 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS15770 869d93cd09aab6c77e6e473467c47bdb 322 SUPERFAMILY SSF46689 199 249 8.07E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS15770 869d93cd09aab6c77e6e473467c47bdb 322 SUPERFAMILY SSF46689 251 301 3.63E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS15770 869d93cd09aab6c77e6e473467c47bdb 322 SMART SM00342 215 298 2.8E-27 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS15770 869d93cd09aab6c77e6e473467c47bdb 322 Pfam PF12852 Cupin 2 183 7.0E-48 T 06-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain SMD11_RS15770 869d93cd09aab6c77e6e473467c47bdb 322 Pfam PF12833 Helix-turn-helix domain 221 299 1.6E-18 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS15770 869d93cd09aab6c77e6e473467c47bdb 322 Gene3D G3DSA:1.10.10.60 197 252 1.1E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS15770 869d93cd09aab6c77e6e473467c47bdb 322 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 252 294 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD11_RS15770 869d93cd09aab6c77e6e473467c47bdb 322 Gene3D G3DSA:1.10.10.60 253 299 8.7E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS23455 94005a7e38761ec5291a846dc2414224 389 Pfam PF00108 Thiolase, N-terminal domain 6 257 1.4E-49 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD11_RS23455 94005a7e38761ec5291a846dc2414224 389 Gene3D G3DSA:3.40.47.10 273 388 1.2E-48 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS23455 94005a7e38761ec5291a846dc2414224 389 Gene3D G3DSA:3.40.47.10 149 184 1.2E-48 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS23455 94005a7e38761ec5291a846dc2414224 389 Pfam PF02803 Thiolase, C-terminal domain 267 387 1.1E-41 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD11_RS23455 94005a7e38761ec5291a846dc2414224 389 PIRSF PIRSF000429 1 389 1.8E-112 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS23455 94005a7e38761ec5291a846dc2414224 389 ProSitePatterns PS00099 Thiolases active site. 370 383 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SMD11_RS23455 94005a7e38761ec5291a846dc2414224 389 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 387 2.2E-113 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS23455 94005a7e38761ec5291a846dc2414224 389 Gene3D G3DSA:3.40.47.10 185 272 1.2E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS23455 94005a7e38761ec5291a846dc2414224 389 Gene3D G3DSA:3.40.47.10 6 125 1.2E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS23455 94005a7e38761ec5291a846dc2414224 389 SUPERFAMILY SSF53901 5 266 6.01E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS23455 94005a7e38761ec5291a846dc2414224 389 SUPERFAMILY SSF53901 267 388 2.4E-39 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS23455 94005a7e38761ec5291a846dc2414224 389 ProSitePatterns PS00737 Thiolases signature 2. 335 351 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMD11_RS12590 40bc8c62258819dd8df38d70fac8f51e 69 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 2 62 9.8E-16 T 06-07-2017 IPR032716 Acyl-CoA carboxylase epsilon subunit SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 PIRSF PIRSF000732 1 556 7.3E-170 T 06-07-2017 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 Gene3D G3DSA:3.20.20.60 252 550 4.1E-87 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 SUPERFAMILY SSF52009 123 238 7.59E-30 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 Gene3D G3DSA:1.10.274.10 28 129 1.1E-20 T 06-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 SUPERFAMILY SSF47831 30 140 1.23E-20 T 06-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 181 192 - T 06-07-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 Pfam PF00391 PEP-utilising enzyme, mobile domain 150 221 9.8E-22 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 545 6.6E-126 T 06-07-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 SUPERFAMILY SSF51621 251 533 6.02E-84 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 253 524 6.7E-79 T 06-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 431 449 - T 06-07-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 484 496 3.7E-17 T 06-07-2017 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 431 446 3.7E-17 T 06-07-2017 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 448 463 3.7E-17 T 06-07-2017 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 285 304 3.7E-17 T 06-07-2017 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 123 1.8E-21 T 06-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SMD11_RS28115 d050237fe9f7b11d8fec8d2a08e2c8e2 556 Gene3D G3DSA:3.50.30.10 130 244 1.1E-33 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD11_RS02040 36cae5c718d7e96681875ad15cf33f19 130 SMART SM00422 8 76 8.5E-17 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS02040 36cae5c718d7e96681875ad15cf33f19 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 9 20 5.4E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS02040 36cae5c718d7e96681875ad15cf33f19 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 33 5.4E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS02040 36cae5c718d7e96681875ad15cf33f19 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 5.4E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS02040 36cae5c718d7e96681875ad15cf33f19 130 Gene3D G3DSA:1.10.1660.10 9 123 4.1E-28 T 06-07-2017 SMD11_RS02040 36cae5c718d7e96681875ad15cf33f19 130 Pfam PF13411 MerR HTH family regulatory protein 9 73 7.5E-17 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS02040 36cae5c718d7e96681875ad15cf33f19 130 SUPERFAMILY SSF46955 9 122 4.76E-25 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS26280 a6e2dbaf8c665be37054634d566a829f 308 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 90 2.0E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS26280 a6e2dbaf8c665be37054634d566a829f 308 Pfam PF13602 Zinc-binding dehydrogenase 189 305 4.6E-19 T 06-07-2017 SMD11_RS26280 a6e2dbaf8c665be37054634d566a829f 308 SUPERFAMILY SSF50129 1 152 3.65E-39 T 06-07-2017 IPR011032 GroES-like SMD11_RS26280 a6e2dbaf8c665be37054634d566a829f 308 Gene3D G3DSA:3.40.50.720 153 242 9.8E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS26280 a6e2dbaf8c665be37054634d566a829f 308 SMART SM00829 10 305 2.9E-33 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS26280 a6e2dbaf8c665be37054634d566a829f 308 SUPERFAMILY SSF51735 119 249 1.4E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS26280 a6e2dbaf8c665be37054634d566a829f 308 Gene3D G3DSA:3.90.180.10 1 152 4.6E-48 T 06-07-2017 IPR011032 GroES-like SMD11_RS03385 567d78d8f6298650d35d4d178b587dc5 279 SUPERFAMILY SSF46894 3 95 4.25E-10 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS03385 567d78d8f6298650d35d4d178b587dc5 279 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 95 3.4E-8 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS03385 567d78d8f6298650d35d4d178b587dc5 279 Gene3D G3DSA:1.25.40.10 113 223 3.4E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS03385 567d78d8f6298650d35d4d178b587dc5 279 SMART SM01043 103 248 6.8E-53 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS03385 567d78d8f6298650d35d4d178b587dc5 279 Pfam PF03704 Bacterial transcriptional activator domain 103 248 6.9E-47 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS03385 567d78d8f6298650d35d4d178b587dc5 279 SMART SM00862 16 96 6.9E-6 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS03385 567d78d8f6298650d35d4d178b587dc5 279 SUPERFAMILY SSF48452 100 259 2.95E-38 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS03385 567d78d8f6298650d35d4d178b587dc5 279 Gene3D G3DSA:1.10.10.10 11 96 8.4E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS24235 36a1f890fe300243e83792d497b6988e 354 SUPERFAMILY SSF52418 87 353 2.09E-83 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS24235 36a1f890fe300243e83792d497b6988e 354 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 19 351 35.357 T 06-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 SMD11_RS24235 36a1f890fe300243e83792d497b6988e 354 SUPERFAMILY SSF47648 16 83 1.16E-19 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS24235 36a1f890fe300243e83792d497b6988e 354 Gene3D G3DSA:3.40.1030.10 86 354 1.7E-105 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS24235 36a1f890fe300243e83792d497b6988e 354 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 22 350 3.8E-109 T 06-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 SMD11_RS24235 36a1f890fe300243e83792d497b6988e 354 Gene3D G3DSA:1.20.970.10 17 80 9.8E-25 T 06-07-2017 SMD11_RS24235 36a1f890fe300243e83792d497b6988e 354 Pfam PF02885 Glycosyl transferase family, helical bundle domain 20 80 7.8E-20 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS24235 36a1f890fe300243e83792d497b6988e 354 Pfam PF00591 Glycosyl transferase family, a/b domain 89 341 3.1E-82 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS19730 ead30a9aa1fe33507eea49a98a6d4f35 144 Gene3D G3DSA:3.10.180.10 9 105 4.1E-7 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS19730 ead30a9aa1fe33507eea49a98a6d4f35 144 SUPERFAMILY SSF54593 4 143 4.48E-7 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS10705 9dad443f4a7824c4da97de7697e075ba 402 Pfam PF00005 ABC transporter 18 156 1.0E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS10705 9dad443f4a7824c4da97de7697e075ba 402 SMART SM00382 26 204 4.0E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS10705 9dad443f4a7824c4da97de7697e075ba 402 SUPERFAMILY SSF52540 2 219 5.74E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10705 9dad443f4a7824c4da97de7697e075ba 402 Gene3D G3DSA:3.40.50.300 1 223 2.4E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20065 126218ab5e09c9e32497ae736da0aa88 305 SUPERFAMILY SSF51556 33 304 2.69E-72 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS20065 126218ab5e09c9e32497ae736da0aa88 305 Pfam PF01026 TatD related DNase 36 303 3.2E-68 T 06-07-2017 IPR001130 TatD family GO:0016788 SMD11_RS20065 126218ab5e09c9e32497ae736da0aa88 305 Gene3D G3DSA:3.20.20.140 27 304 3.3E-78 T 06-07-2017 SMD11_RS20065 126218ab5e09c9e32497ae736da0aa88 305 PIRSF PIRSF005902 26 305 2.8E-67 T 06-07-2017 IPR001130 TatD family GO:0016788 SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 277 284 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 SUPERFAMILY SSF51230 615 687 6.28E-18 T 06-07-2017 IPR011053 Single hybrid motif SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 SUPERFAMILY SSF52440 2 113 3.6E-45 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 Gene3D G3DSA:2.40.50.100 619 687 4.0E-21 T 06-07-2017 SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 1.8E-41 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 144 312 3.4E-58 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 Gene3D G3DSA:3.30.1490.20 144 193 2.4E-18 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 SUPERFAMILY SSF51246 397 491 1.36E-19 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 SUPERFAMILY SSF51246 319 350 8.37E-7 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 SUPERFAMILY SSF56059 83 316 5.3E-58 T 06-07-2017 SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 Gene3D G3DSA:3.30.470.20 407 490 6.8E-79 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 Gene3D G3DSA:3.30.470.20 194 349 6.8E-79 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 644 661 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 Pfam PF00364 Biotin-requiring enzyme 622 686 1.1E-14 T 06-07-2017 IPR000089 Biotin/lipoyl attachment SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 SMART SM00878 324 487 2.3E-32 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 Gene3D G3DSA:3.40.50.20 3 130 5.9E-47 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS13625 ebb8c85c128095edef0e0bfb70fe59b4 699 Pfam PF02785 Biotin carboxylase C-terminal domain 398 487 2.5E-18 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS00250 a603868438173736e53e08e9fe8f79df 526 SUPERFAMILY SSF140864 20 354 7.72E-51 T 06-07-2017 SMD11_RS00250 a603868438173736e53e08e9fe8f79df 526 SUPERFAMILY SSF53300 355 514 4.09E-12 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS00250 a603868438173736e53e08e9fe8f79df 526 Pfam PF05731 TROVE domain 258 333 2.8E-15 T 06-07-2017 IPR008858 TROVE domain GO:0003723 SMD11_RS05150 d82c00be0f67580514cac5f1eedaa36b 216 Pfam PF00571 CBS domain 8 61 1.1E-9 T 06-07-2017 IPR000644 CBS domain SMD11_RS05150 d82c00be0f67580514cac5f1eedaa36b 216 Pfam PF00571 CBS domain 89 143 8.8E-17 T 06-07-2017 IPR000644 CBS domain SMD11_RS05150 d82c00be0f67580514cac5f1eedaa36b 216 PIRSF PIRSF036990 6 216 1.2E-61 T 06-07-2017 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON SMD11_RS05150 d82c00be0f67580514cac5f1eedaa36b 216 SMART SM00116 15 63 0.017 T 06-07-2017 IPR000644 CBS domain SMD11_RS05150 d82c00be0f67580514cac5f1eedaa36b 216 SMART SM00116 96 144 6.9E-13 T 06-07-2017 IPR000644 CBS domain SMD11_RS05150 d82c00be0f67580514cac5f1eedaa36b 216 Pfam PF04972 BON domain 146 208 5.9E-10 T 06-07-2017 IPR007055 BON domain SMD11_RS05150 d82c00be0f67580514cac5f1eedaa36b 216 SUPERFAMILY SSF54631 5 149 1.52E-34 T 06-07-2017 SMD11_RS05150 d82c00be0f67580514cac5f1eedaa36b 216 Gene3D G3DSA:3.20.20.70 3 161 8.1E-32 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS07315 945c978e5709643242ce387fd17091ee 135 Pfam PF01641 SelR domain 11 132 1.4E-51 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 SMD11_RS07315 945c978e5709643242ce387fd17091ee 135 Gene3D G3DSA:2.170.150.20 2 134 2.2E-59 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 SMD11_RS07315 945c978e5709643242ce387fd17091ee 135 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 133 2.9E-48 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 SMD11_RS07315 945c978e5709643242ce387fd17091ee 135 SUPERFAMILY SSF51316 5 134 1.67E-54 T 06-07-2017 IPR011057 Mss4-like SMD11_RS28085 700c117421d76a0d5729d3f7b3d3564b 262 Pfam PF01427 D-ala-D-ala dipeptidase 40 163 1.0E-15 T 06-07-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMD11_RS28085 700c117421d76a0d5729d3f7b3d3564b 262 Pfam PF01427 D-ala-D-ala dipeptidase 193 261 1.3E-15 T 06-07-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMD11_RS28085 700c117421d76a0d5729d3f7b3d3564b 262 PIRSF PIRSF026671 9 262 7.6E-72 T 06-07-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMD11_RS28085 700c117421d76a0d5729d3f7b3d3564b 262 Gene3D G3DSA:3.30.1380.10 39 261 1.1E-71 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 SMD11_RS28085 700c117421d76a0d5729d3f7b3d3564b 262 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 40 260 31.127 T 06-07-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 SMD11_RS28085 700c117421d76a0d5729d3f7b3d3564b 262 SUPERFAMILY SSF55166 38 261 7.85E-60 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 SMD11_RS18130 4d4c6a207c35bfe79469407e77f6e9bb 246 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 80 4.7E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS18130 4d4c6a207c35bfe79469407e77f6e9bb 246 SUPERFAMILY SSF46689 24 106 1.65E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS18130 4d4c6a207c35bfe79469407e77f6e9bb 246 SUPERFAMILY SSF48498 163 241 1.04E-12 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS18130 4d4c6a207c35bfe79469407e77f6e9bb 246 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 49 8.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS18130 4d4c6a207c35bfe79469407e77f6e9bb 246 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 8.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS18130 4d4c6a207c35bfe79469407e77f6e9bb 246 Gene3D G3DSA:1.10.357.10 24 244 3.5E-62 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS29370 2c6bed7c25abd320115a06c08264bca5 344 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 50 190 1.0E-16 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS29370 2c6bed7c25abd320115a06c08264bca5 344 SUPERFAMILY SSF53901 23 224 6.65E-29 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29370 2c6bed7c25abd320115a06c08264bca5 344 Gene3D G3DSA:3.40.47.10 49 230 2.7E-24 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS01100 f6497d1f94339969960cb7e7db29f690 67 Gene3D G3DSA:3.30.300.30 21 60 2.8E-5 T 06-07-2017 SMD11_RS01100 f6497d1f94339969960cb7e7db29f690 67 SUPERFAMILY SSF56801 20 60 6.02E-6 T 06-07-2017 SMD11_RS27985 42988ca31bfa230206af23b9156cf6a0 540 SUPERFAMILY SSF52467 193 338 1.41E-50 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS27985 42988ca31bfa230206af23b9156cf6a0 540 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 531 6.0E-25 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMD11_RS27985 42988ca31bfa230206af23b9156cf6a0 540 SUPERFAMILY SSF52518 3 170 4.79E-40 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS27985 42988ca31bfa230206af23b9156cf6a0 540 Gene3D G3DSA:3.40.50.970 354 535 9.4E-44 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS27985 42988ca31bfa230206af23b9156cf6a0 540 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 329 2.9E-18 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMD11_RS27985 42988ca31bfa230206af23b9156cf6a0 540 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 169 4.5E-43 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMD11_RS27985 42988ca31bfa230206af23b9156cf6a0 540 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 420 439 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 SMD11_RS27985 42988ca31bfa230206af23b9156cf6a0 540 SUPERFAMILY SSF52518 360 535 1.07E-40 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS27985 42988ca31bfa230206af23b9156cf6a0 540 Gene3D G3DSA:3.40.50.1220 191 339 8.3E-38 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS27985 42988ca31bfa230206af23b9156cf6a0 540 Gene3D G3DSA:3.40.50.970 2 172 3.0E-46 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS15385 60b1b29f5000367e3ad6e4cae7dd992a 320 Pfam PF12697 Alpha/beta hydrolase family 52 305 4.4E-21 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS15385 60b1b29f5000367e3ad6e4cae7dd992a 320 Gene3D G3DSA:3.40.50.1820 14 315 1.1E-71 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15385 60b1b29f5000367e3ad6e4cae7dd992a 320 PRINTS PR00111 Alpha/beta hydrolase fold signature 76 91 1.1E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS15385 60b1b29f5000367e3ad6e4cae7dd992a 320 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 1.1E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS15385 60b1b29f5000367e3ad6e4cae7dd992a 320 PRINTS PR00111 Alpha/beta hydrolase fold signature 134 147 1.1E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS15385 60b1b29f5000367e3ad6e4cae7dd992a 320 SUPERFAMILY SSF53474 28 315 6.22E-66 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15385 60b1b29f5000367e3ad6e4cae7dd992a 320 PRINTS PR00412 Epoxide hydrolase signature 256 272 4.4E-23 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 SMD11_RS15385 60b1b29f5000367e3ad6e4cae7dd992a 320 PRINTS PR00412 Epoxide hydrolase signature 56 74 4.4E-23 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 SMD11_RS15385 60b1b29f5000367e3ad6e4cae7dd992a 320 PRINTS PR00412 Epoxide hydrolase signature 76 91 4.4E-23 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 SMD11_RS15385 60b1b29f5000367e3ad6e4cae7dd992a 320 PRINTS PR00412 Epoxide hydrolase signature 134 147 4.4E-23 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 SMD11_RS15385 60b1b29f5000367e3ad6e4cae7dd992a 320 PRINTS PR00412 Epoxide hydrolase signature 120 133 4.4E-23 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 SMD11_RS15385 60b1b29f5000367e3ad6e4cae7dd992a 320 PRINTS PR00412 Epoxide hydrolase signature 290 312 4.4E-23 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 SMD11_RS07990 1ec43ce673d0b7636ad3137b9c827ab4 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.0E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS07990 1ec43ce673d0b7636ad3137b9c827ab4 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.0E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS07990 1ec43ce673d0b7636ad3137b9c827ab4 202 SUPERFAMILY SSF48498 85 199 1.08E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS07990 1ec43ce673d0b7636ad3137b9c827ab4 202 SUPERFAMILY SSF46689 14 81 6.48E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS07990 1ec43ce673d0b7636ad3137b9c827ab4 202 Pfam PF16859 Bacterial transcriptional repressor C-terminal 81 192 2.1E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS07990 1ec43ce673d0b7636ad3137b9c827ab4 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 9.0E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS07990 1ec43ce673d0b7636ad3137b9c827ab4 202 Gene3D G3DSA:1.10.357.10 59 200 1.4E-39 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS07990 1ec43ce673d0b7636ad3137b9c827ab4 202 Gene3D G3DSA:1.10.10.60 14 58 8.7E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS05140 588a4b89625d09c51b0ba5a242020e5b 293 PRINTS PR01438 Universal stress protein signature 129 151 7.2E-13 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS05140 588a4b89625d09c51b0ba5a242020e5b 293 PRINTS PR01438 Universal stress protein signature 17 35 7.2E-13 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS05140 588a4b89625d09c51b0ba5a242020e5b 293 PRINTS PR01438 Universal stress protein signature 111 123 7.2E-13 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS05140 588a4b89625d09c51b0ba5a242020e5b 293 SUPERFAMILY SSF52402 165 291 3.27E-15 T 06-07-2017 SMD11_RS05140 588a4b89625d09c51b0ba5a242020e5b 293 SUPERFAMILY SSF52402 18 153 2.76E-28 T 06-07-2017 SMD11_RS05140 588a4b89625d09c51b0ba5a242020e5b 293 Pfam PF00582 Universal stress protein family 165 291 1.1E-12 T 06-07-2017 IPR006016 UspA GO:0006950 SMD11_RS05140 588a4b89625d09c51b0ba5a242020e5b 293 Pfam PF00582 Universal stress protein family 18 151 6.9E-24 T 06-07-2017 IPR006016 UspA GO:0006950 SMD11_RS05140 588a4b89625d09c51b0ba5a242020e5b 293 Gene3D G3DSA:3.40.50.620 17 151 9.7E-31 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS05140 588a4b89625d09c51b0ba5a242020e5b 293 Gene3D G3DSA:3.40.50.620 163 291 2.8E-16 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS19185 fb59755f9217b23862936ca4c14560eb 222 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 206 6.5E-56 T 06-07-2017 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 SMD11_RS19185 fb59755f9217b23862936ca4c14560eb 222 Pfam PF00814 Glycoprotease family 32 147 3.1E-26 T 06-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS19185 fb59755f9217b23862936ca4c14560eb 222 SUPERFAMILY SSF53067 111 204 3.24E-10 T 06-07-2017 SMD11_RS19185 fb59755f9217b23862936ca4c14560eb 222 Gene3D G3DSA:3.30.420.40 2 129 1.7E-36 T 06-07-2017 SMD11_RS19185 fb59755f9217b23862936ca4c14560eb 222 SUPERFAMILY SSF53067 2 102 1.17E-22 T 06-07-2017 SMD11_RS02410 634f43514eaa1e32e8679a1224faf98a 401 SUPERFAMILY SSF51905 267 369 2.54E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02410 634f43514eaa1e32e8679a1224faf98a 401 SUPERFAMILY SSF51905 3 165 2.54E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02410 634f43514eaa1e32e8679a1224faf98a 401 Pfam PF01494 FAD binding domain 4 161 2.8E-9 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS02410 634f43514eaa1e32e8679a1224faf98a 401 Gene3D G3DSA:3.50.50.60 270 348 3.3E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02410 634f43514eaa1e32e8679a1224faf98a 401 Gene3D G3DSA:3.50.50.60 2 171 3.3E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02410 634f43514eaa1e32e8679a1224faf98a 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 2.7E-9 T 06-07-2017 SMD11_RS02410 634f43514eaa1e32e8679a1224faf98a 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 2.7E-9 T 06-07-2017 SMD11_RS02410 634f43514eaa1e32e8679a1224faf98a 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 2.7E-9 T 06-07-2017 SMD11_RS10735 6d88dfd6ab11c9bc48cd4a3c5a3e2006 878 SUPERFAMILY SSF52540 102 297 2.13E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10735 6d88dfd6ab11c9bc48cd4a3c5a3e2006 878 Gene3D G3DSA:3.40.50.300 104 223 3.4E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11000 80b453bac561e3b7a31077d5abf72ede 278 SMART SM00849 50 255 2.0E-10 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS11000 80b453bac561e3b7a31077d5abf72ede 278 Pfam PF00753 Metallo-beta-lactamase superfamily 55 240 1.0E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS11000 80b453bac561e3b7a31077d5abf72ede 278 SUPERFAMILY SSF56281 3 274 7.85E-32 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS11000 80b453bac561e3b7a31077d5abf72ede 278 Gene3D G3DSA:3.60.15.10 2 269 1.9E-41 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS24715 fda1ebc4531c1d87365df1884406a089 210 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 5 185 4.3E-38 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD11_RS24715 fda1ebc4531c1d87365df1884406a089 210 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 5 203 3.5E-78 T 06-07-2017 IPR017519 Conserved hypothetical protein CHP03085 SMD11_RS24715 fda1ebc4531c1d87365df1884406a089 210 SUPERFAMILY SSF109854 12 114 4.58E-5 T 06-07-2017 SMD11_RS20155 6bafc8c0b337adc59c395fc1c210fd68 917 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 566 578 - T 06-07-2017 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMD11_RS20155 6bafc8c0b337adc59c395fc1c210fd68 917 Gene3D G3DSA:1.20.1440.90 282 403 9.0E-24 T 06-07-2017 SMD11_RS20155 6bafc8c0b337adc59c395fc1c210fd68 917 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 245 260 2.3E-57 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMD11_RS20155 6bafc8c0b337adc59c395fc1c210fd68 917 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 743 769 2.3E-57 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMD11_RS20155 6bafc8c0b337adc59c395fc1c210fd68 917 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 400 420 2.3E-57 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMD11_RS20155 6bafc8c0b337adc59c395fc1c210fd68 917 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 137 150 2.3E-57 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMD11_RS20155 6bafc8c0b337adc59c395fc1c210fd68 917 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 606 635 2.3E-57 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMD11_RS20155 6bafc8c0b337adc59c395fc1c210fd68 917 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 564 584 2.3E-57 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMD11_RS20155 6bafc8c0b337adc59c395fc1c210fd68 917 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 187 203 2.3E-57 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMD11_RS20155 6bafc8c0b337adc59c395fc1c210fd68 917 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 11 917 18.134 T 06-07-2017 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMD11_RS20155 6bafc8c0b337adc59c395fc1c210fd68 917 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 138 149 - T 06-07-2017 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMD11_RS20155 6bafc8c0b337adc59c395fc1c210fd68 917 SUPERFAMILY SSF51621 23 917 1.01E-270 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS20155 6bafc8c0b337adc59c395fc1c210fd68 917 Pfam PF00311 Phosphoenolpyruvate carboxylase 133 917 3.0E-286 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Pfam PF00668 Condensation domain 1068 1367 1.8E-61 T 06-07-2017 IPR001242 Condensation domain SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Pfam PF00668 Condensation domain 2536 2746 1.0E-34 T 06-07-2017 IPR001242 Condensation domain SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Pfam PF00668 Condensation domain 1 300 5.3E-61 T 06-07-2017 IPR001242 Condensation domain SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Gene3D G3DSA:2.30.38.10 1845 1922 1.4E-24 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Gene3D G3DSA:2.30.38.10 791 869 2.5E-26 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Pfam PF00501 AMP-binding enzyme 472 879 2.0E-79 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Pfam PF00501 AMP-binding enzyme 1539 1933 1.9E-92 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Pfam PF00550 Phosphopantetheine attachment site 988 1049 1.2E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Pfam PF00550 Phosphopantetheine attachment site 2454 2517 2.6E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Gene3D G3DSA:3.40.50.980 1686 1844 6.2E-40 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Gene3D G3DSA:3.40.50.980 623 790 2.4E-41 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Pfam PF13745 HxxPF-repeated domain 323 415 4.4E-21 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Pfam PF13745 HxxPF-repeated domain 1389 1484 8.2E-29 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1009 1024 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 SUPERFAMILY SSF52777 190 456 2.22E-57 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Pfam PF08241 Methyltransferase domain 2047 2149 2.6E-9 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 SUPERFAMILY SSF47336 979 1082 1.18E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 SUPERFAMILY SSF47336 2445 2517 1.57E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Gene3D G3DSA:3.40.50.980 1533 1685 1.4E-46 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 SUPERFAMILY SSF56801 429 998 2.22E-136 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 491 902 1.2E-116 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1561 1957 2.7E-132 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Pfam PF13193 AMP-binding enzyme C-terminal domain 887 958 9.1E-8 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Gene3D G3DSA:3.40.50.150 2320 2349 3.5E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Gene3D G3DSA:3.40.50.150 2028 2163 3.5E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Gene3D G3DSA:3.40.50.150 2229 2230 3.5E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2476 2491 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 SUPERFAMILY SSF53335 2010 2155 1.95E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 SUPERFAMILY SSF52777 1256 1525 2.67E-61 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 SUPERFAMILY SSF52777 2531 2738 2.67E-45 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Gene3D G3DSA:3.30.300.30 874 987 7.1E-32 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Gene3D G3DSA:3.30.300.30 2394 2455 1.2E-34 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Gene3D G3DSA:3.30.300.30 1928 1983 1.2E-34 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 ProSitePatterns PS00455 Putative AMP-binding domain signature. 617 628 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Gene3D G3DSA:3.40.50.980 466 622 6.1E-30 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 SUPERFAMILY SSF52777 1071 1243 2.11E-51 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1678 1689 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 SUPERFAMILY SSF52777 4 176 3.78E-50 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 SUPERFAMILY SSF56801 2389 2465 6.54E-153 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 SUPERFAMILY SSF56801 1498 1987 6.54E-153 T 06-07-2017 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Gene3D G3DSA:1.10.1200.10 988 1055 9.0E-28 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 Gene3D G3DSA:1.10.1200.10 2456 2523 1.9E-27 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 SMART SM00823 Phosphopantetheine attachment site 985 1054 9.6E-12 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29980 ae3b45aa58389f826cd31345f842598c 2796 SMART SM00823 Phosphopantetheine attachment site 2452 2521 1.9E-10 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 Pfam PF02151 UvrB/uvrC motif 421 453 6.9E-7 T 06-07-2017 IPR001943 UVR domain GO:0005515 SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 Gene3D G3DSA:3.40.50.300 702 730 4.9E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 Gene3D G3DSA:3.40.50.300 494 667 4.9E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 SMART SM00382 204 348 5.9E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 SMART SM00382 541 689 1.1E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 Gene3D G3DSA:1.10.8.60 350 432 7.3E-34 T 06-07-2017 SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 Pfam PF07724 AAA domain (Cdc48 subfamily) 541 712 5.5E-54 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 619 637 6.2E-40 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 545 563 6.2E-40 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 590 608 6.2E-40 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 666 6.2E-40 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 Gene3D G3DSA:1.10.8.60 731 816 2.7E-31 T 06-07-2017 SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 719 798 5.2E-26 T 06-07-2017 IPR019489 Clp ATPase, C-terminal SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 Gene3D G3DSA:1.10.1780.10 1 143 3.1E-54 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 3.2E-19 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 4.5E-17 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 SUPERFAMILY SSF52540 167 450 5.14E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 SMART SM01086 719 812 7.8E-37 T 06-07-2017 IPR019489 Clp ATPase, C-terminal SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 SUPERFAMILY SSF52540 490 800 6.0E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 209 329 1.1E-12 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 SUPERFAMILY SSF81923 3 144 3.63E-33 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS14800 657bc42c5ff4bc89fece6d0f7aba3c33 841 Gene3D G3DSA:3.40.50.300 167 347 5.1E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25150 ecb54e483f2514c05146642acb8be65f 259 Gene3D G3DSA:3.40.50.1360 4 249 2.6E-75 T 06-07-2017 SMD11_RS25150 ecb54e483f2514c05146642acb8be65f 259 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 8 249 2.7E-79 T 06-07-2017 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 SMD11_RS25150 ecb54e483f2514c05146642acb8be65f 259 SUPERFAMILY SSF100950 6 252 2.18E-63 T 06-07-2017 SMD11_RS25150 ecb54e483f2514c05146642acb8be65f 259 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 239 1.4E-73 T 06-07-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 SMD11_RS09750 e0f629448d7b2320082f11f52fbeab92 332 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 9 316 3.2E-85 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 SMD11_RS09750 e0f629448d7b2320082f11f52fbeab92 332 Pfam PF02769 AIR synthase related protein, C-terminal domain 156 243 9.5E-6 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain SMD11_RS09750 e0f629448d7b2320082f11f52fbeab92 332 Gene3D G3DSA:3.90.650.10 151 316 8.1E-52 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain SMD11_RS09750 e0f629448d7b2320082f11f52fbeab92 332 Pfam PF00586 AIR synthase related protein, N-terminal domain 33 142 6.1E-22 T 06-07-2017 IPR016188 PurM-like, N-terminal domain SMD11_RS09750 e0f629448d7b2320082f11f52fbeab92 332 SUPERFAMILY SSF55326 5 142 1.23E-34 T 06-07-2017 SMD11_RS09750 e0f629448d7b2320082f11f52fbeab92 332 PIRSF PIRSF005303 4 316 1.9E-90 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 SMD11_RS09750 e0f629448d7b2320082f11f52fbeab92 332 SUPERFAMILY SSF56042 148 297 8.02E-34 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain SMD11_RS09750 e0f629448d7b2320082f11f52fbeab92 332 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 8 313 28.951 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 SMD11_RS09750 e0f629448d7b2320082f11f52fbeab92 332 Gene3D G3DSA:3.30.1330.10 4 145 9.5E-46 T 06-07-2017 IPR016188 PurM-like, N-terminal domain SMD11_RS22895 2944725085f47dca41017d75d983d5be 413 SMART SM00387 322 413 5.0E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS22895 2944725085f47dca41017d75d983d5be 413 SUPERFAMILY SSF55874 307 410 9.31E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS22895 2944725085f47dca41017d75d983d5be 413 Pfam PF07730 Histidine kinase 222 289 2.1E-15 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS22895 2944725085f47dca41017d75d983d5be 413 Gene3D G3DSA:3.30.565.10 327 411 4.7E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08390 21aaf3b0b3a311631c377579e3aa5fe2 238 Pfam PF00925 GTP cyclohydrolase II 50 207 3.5E-52 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMD11_RS08390 21aaf3b0b3a311631c377579e3aa5fe2 238 SUPERFAMILY SSF142695 38 207 1.44E-49 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMD11_RS33955 8ee50444692da1cdd33bf35c3a662111 483 SUPERFAMILY SSF52402 4 185 2.96E-32 T 06-07-2017 SMD11_RS33955 8ee50444692da1cdd33bf35c3a662111 483 Gene3D G3DSA:3.40.50.620 4 175 3.3E-41 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS33955 8ee50444692da1cdd33bf35c3a662111 483 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 420 1.1E-138 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS33955 8ee50444692da1cdd33bf35c3a662111 483 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS33955 8ee50444692da1cdd33bf35c3a662111 483 SUPERFAMILY SSF69864 190 438 6.02E-74 T 06-07-2017 SMD11_RS33955 8ee50444692da1cdd33bf35c3a662111 483 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 474 78.62 T 06-07-2017 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS33955 8ee50444692da1cdd33bf35c3a662111 483 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS33955 8ee50444692da1cdd33bf35c3a662111 483 Gene3D G3DSA:1.10.287.400 379 438 2.6E-28 T 06-07-2017 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS33955 8ee50444692da1cdd33bf35c3a662111 483 Pfam PF00764 Arginosuccinate synthase 16 393 2.5E-55 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS33955 8ee50444692da1cdd33bf35c3a662111 483 Gene3D G3DSA:3.90.1260.10 176 373 1.6E-62 T 06-07-2017 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS30180 69596f58ed55e40abc07d0048272b808 472 Pfam PF09362 Domain of unknown function (DUF1996) 230 452 4.0E-26 T 06-07-2017 IPR018535 Domain of unknown function DUF1996 SMD11_RS23810 5e0689f792ed55a1b040dd64bb84ee2c 339 Gene3D G3DSA:3.60.10.10 122 274 1.1E-10 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS23810 5e0689f792ed55a1b040dd64bb84ee2c 339 SUPERFAMILY SSF56219 123 338 1.57E-29 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS23810 5e0689f792ed55a1b040dd64bb84ee2c 339 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 128 330 2.8E-18 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS24285 caf910b6659f6adebc01b7c5cc59fd0a 380 SUPERFAMILY SSF53756 5 380 1.3E-76 T 06-07-2017 SMD11_RS24285 caf910b6659f6adebc01b7c5cc59fd0a 380 Gene3D G3DSA:3.40.50.2000 165 361 5.5E-38 T 06-07-2017 SMD11_RS24285 caf910b6659f6adebc01b7c5cc59fd0a 380 Pfam PF13439 Glycosyltransferase Family 4 16 178 1.4E-8 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 SMD11_RS24285 caf910b6659f6adebc01b7c5cc59fd0a 380 Pfam PF00534 Glycosyl transferases group 1 195 362 6.7E-43 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 SMD11_RS13225 f4db82d7b5fb9510f105d226b3b333f7 212 Pfam PF00551 Formyl transferase 13 194 1.0E-52 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS13225 f4db82d7b5fb9510f105d226b3b333f7 212 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 146 169 - T 06-07-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS13225 f4db82d7b5fb9510f105d226b3b333f7 212 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 12 203 5.4E-70 T 06-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 SMD11_RS13225 f4db82d7b5fb9510f105d226b3b333f7 212 Gene3D G3DSA:3.40.50.170 12 207 9.4E-70 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS13225 f4db82d7b5fb9510f105d226b3b333f7 212 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 13 200 29.709 T 06-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 SMD11_RS13225 f4db82d7b5fb9510f105d226b3b333f7 212 SUPERFAMILY SSF53328 13 208 1.1E-59 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS08190 8e1dbc49912809760e4daf1a79cf549e 155 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 50 68 - T 06-07-2017 IPR030489 Transcription regulator Rrf2-type, conserved site SMD11_RS08190 8e1dbc49912809760e4daf1a79cf549e 155 SUPERFAMILY SSF46785 2 132 1.91E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08190 8e1dbc49912809760e4daf1a79cf549e 155 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 131 5.5E-32 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type SMD11_RS08190 8e1dbc49912809760e4daf1a79cf549e 155 Pfam PF02082 Transcriptional regulator 2 84 2.7E-24 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type SMD11_RS08190 8e1dbc49912809760e4daf1a79cf549e 155 Gene3D G3DSA:1.10.10.10 2 132 2.2E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS25260 b608392ebfd445f11e3b540bbe485601 329 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 121 161 1.2E-16 T 06-07-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 SMD11_RS25260 b608392ebfd445f11e3b540bbe485601 329 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 9 326 43.4 T 06-07-2017 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 SMD11_RS25260 b608392ebfd445f11e3b540bbe485601 329 Gene3D G3DSA:2.160.10.10 162 317 3.4E-34 T 06-07-2017 SMD11_RS25260 b608392ebfd445f11e3b540bbe485601 329 Gene3D G3DSA:3.30.60.70 121 161 1.4E-13 T 06-07-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 SMD11_RS25260 b608392ebfd445f11e3b540bbe485601 329 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 243 275 1.4E-14 T 06-07-2017 IPR001451 Hexapeptide repeat SMD11_RS25260 b608392ebfd445f11e3b540bbe485601 329 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 11 328 1.9E-152 T 06-07-2017 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 SMD11_RS25260 b608392ebfd445f11e3b540bbe485601 329 SUPERFAMILY SSF51161 81 308 1.15E-38 T 06-07-2017 IPR011004 Trimeric LpxA-like SMD11_RS23730 537c62785125d786a39a7f36adc92c29 462 Gene3D G3DSA:1.20.1250.20 258 447 8.1E-7 T 06-07-2017 SMD11_RS23730 537c62785125d786a39a7f36adc92c29 462 Gene3D G3DSA:1.20.1250.20 66 235 2.4E-29 T 06-07-2017 SMD11_RS23730 537c62785125d786a39a7f36adc92c29 462 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 58 440 4.3E-100 T 06-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 SMD11_RS23730 537c62785125d786a39a7f36adc92c29 462 SUPERFAMILY SSF103473 45 448 7.19E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS23730 537c62785125d786a39a7f36adc92c29 462 Pfam PF07690 Major Facilitator Superfamily 71 409 3.4E-41 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS23730 537c62785125d786a39a7f36adc92c29 462 ProSitePatterns PS00216 Sugar transport proteins signature 1. 113 129 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS17220 aaf21c8a15c27d3b7456f834407d78f4 550 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 44 67 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS17220 aaf21c8a15c27d3b7456f834407d78f4 550 SUPERFAMILY SSF56112 36 299 8.94E-73 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS17220 aaf21c8a15c27d3b7456f834407d78f4 550 Gene3D G3DSA:3.30.200.20 34 121 5.0E-24 T 06-07-2017 SMD11_RS17220 aaf21c8a15c27d3b7456f834407d78f4 550 Pfam PF00069 Protein kinase domain 38 293 2.4E-46 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS17220 aaf21c8a15c27d3b7456f834407d78f4 550 Gene3D G3DSA:1.10.510.10 129 301 7.4E-50 T 06-07-2017 SMD11_RS17220 aaf21c8a15c27d3b7456f834407d78f4 550 Gene3D G3DSA:1.10.510.10 432 462 7.4E-50 T 06-07-2017 SMD11_RS17220 aaf21c8a15c27d3b7456f834407d78f4 550 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 161 173 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS17220 aaf21c8a15c27d3b7456f834407d78f4 550 SMART SM00220 38 303 2.9E-57 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS28460 bc733568417edbbf2d8fbd59b84941c8 641 SUPERFAMILY SSF63825 43 305 9.42E-42 T 06-07-2017 SMD11_RS28460 bc733568417edbbf2d8fbd59b84941c8 641 Pfam PF01436 NHL repeat 44 69 1.0E-5 T 06-07-2017 IPR001258 NHL repeat GO:0005515 SMD11_RS28460 bc733568417edbbf2d8fbd59b84941c8 641 Pfam PF01436 NHL repeat 328 354 2.4E-6 T 06-07-2017 IPR001258 NHL repeat GO:0005515 SMD11_RS28460 bc733568417edbbf2d8fbd59b84941c8 641 Pfam PF01436 NHL repeat 271 296 2.5E-6 T 06-07-2017 IPR001258 NHL repeat GO:0005515 SMD11_RS28460 bc733568417edbbf2d8fbd59b84941c8 641 Pfam PF01436 NHL repeat 158 183 7.9E-7 T 06-07-2017 IPR001258 NHL repeat GO:0005515 SMD11_RS28460 bc733568417edbbf2d8fbd59b84941c8 641 Pfam PF01436 NHL repeat 101 127 1.1E-8 T 06-07-2017 IPR001258 NHL repeat GO:0005515 SMD11_RS28460 bc733568417edbbf2d8fbd59b84941c8 641 Gene3D G3DSA:2.120.10.30 310 356 1.6E-10 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS28460 bc733568417edbbf2d8fbd59b84941c8 641 Gene3D G3DSA:2.120.10.30 21 309 2.2E-64 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS09655 69099035437edb5e43e56d8fcba7c848 411 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 132 410 58.671 T 06-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 SMD11_RS09655 69099035437edb5e43e56d8fcba7c848 411 SUPERFAMILY SSF47364 105 183 4.19E-19 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD11_RS09655 69099035437edb5e43e56d8fcba7c848 411 SMART SM00963 109 189 1.3E-23 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD11_RS09655 69099035437edb5e43e56d8fcba7c848 411 Gene3D G3DSA:1.20.120.140 134 221 8.3E-27 T 06-07-2017 SMD11_RS09655 69099035437edb5e43e56d8fcba7c848 411 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 133 408 6.2E-103 T 06-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 SMD11_RS09655 69099035437edb5e43e56d8fcba7c848 411 Gene3D G3DSA:3.40.50.300 222 410 2.4E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09655 69099035437edb5e43e56d8fcba7c848 411 Pfam PF00448 SRP54-type protein, GTPase domain 212 409 6.7E-73 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD11_RS09655 69099035437edb5e43e56d8fcba7c848 411 SMART SM00382 210 360 4.8E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS09655 69099035437edb5e43e56d8fcba7c848 411 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 383 396 - T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD11_RS09655 69099035437edb5e43e56d8fcba7c848 411 SMART SM00962 211 410 2.9E-104 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD11_RS09655 69099035437edb5e43e56d8fcba7c848 411 Pfam PF02881 SRP54-type protein, helical bundle domain 120 185 3.7E-13 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD11_RS09655 69099035437edb5e43e56d8fcba7c848 411 SUPERFAMILY SSF52540 209 409 1.64E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24115 16c93bd14238f183e4bac22132aa0141 397 Gene3D G3DSA:3.60.15.10 1 73 1.1E-8 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS24115 16c93bd14238f183e4bac22132aa0141 397 SUPERFAMILY SSF52540 223 396 2.39E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24115 16c93bd14238f183e4bac22132aa0141 397 Gene3D G3DSA:3.40.50.300 223 396 1.2E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24115 16c93bd14238f183e4bac22132aa0141 397 SUPERFAMILY SSF56281 1 137 3.48E-6 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS24115 16c93bd14238f183e4bac22132aa0141 397 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 223 395 4.6E-51 T 06-07-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD11_RS01735 21c708244bb770d5965732c59819b82a 213 SUPERFAMILY SSF46689 2 68 1.51E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS01735 21c708244bb770d5965732c59819b82a 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 5.3E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS01735 21c708244bb770d5965732c59819b82a 213 SUPERFAMILY SSF48498 76 183 7.67E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS01735 21c708244bb770d5965732c59819b82a 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 7.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS01735 21c708244bb770d5965732c59819b82a 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 7.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS01735 21c708244bb770d5965732c59819b82a 213 Gene3D G3DSA:1.10.357.10 2 188 5.1E-39 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS21700 7aedbc14e00a735a625ae4c2cb1c5170 173 SUPERFAMILY SSF52402 40 173 4.35E-22 T 06-07-2017 SMD11_RS21700 7aedbc14e00a735a625ae4c2cb1c5170 173 PRINTS PR01438 Universal stress protein signature 151 173 1.6E-6 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS21700 7aedbc14e00a735a625ae4c2cb1c5170 173 PRINTS PR01438 Universal stress protein signature 37 55 1.6E-6 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS21700 7aedbc14e00a735a625ae4c2cb1c5170 173 Gene3D G3DSA:3.40.50.620 39 173 4.0E-33 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS21700 7aedbc14e00a735a625ae4c2cb1c5170 173 Pfam PF00582 Universal stress protein family 40 173 2.6E-23 T 06-07-2017 IPR006016 UspA GO:0006950 SMD11_RS32755 72809aaaa3ba4990ee4350f0d16f2a48 401 SUPERFAMILY SSF53756 1 397 1.03E-77 T 06-07-2017 SMD11_RS32755 72809aaaa3ba4990ee4350f0d16f2a48 401 Gene3D G3DSA:3.40.50.2000 242 383 4.0E-49 T 06-07-2017 SMD11_RS32755 72809aaaa3ba4990ee4350f0d16f2a48 401 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 127 1.2E-9 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD11_RS32755 72809aaaa3ba4990ee4350f0d16f2a48 401 Gene3D G3DSA:3.40.50.2000 1 241 1.9E-51 T 06-07-2017 SMD11_RS20600 ccb888dbd90b96e875f97cb6bb6f820f 446 Gene3D G3DSA:1.20.5.100 213 238 1.3E-16 T 06-07-2017 SMD11_RS20600 ccb888dbd90b96e875f97cb6bb6f820f 446 SUPERFAMILY SSF51735 4 198 1.38E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20600 ccb888dbd90b96e875f97cb6bb6f820f 446 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 327 427 5.2E-23 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD11_RS20600 ccb888dbd90b96e875f97cb6bb6f820f 446 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 424 7.6E-121 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMD11_RS20600 ccb888dbd90b96e875f97cb6bb6f820f 446 Gene3D G3DSA:3.40.50.720 242 445 1.0E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20600 ccb888dbd90b96e875f97cb6bb6f820f 446 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 210 303 1.9E-30 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD11_RS20600 ccb888dbd90b96e875f97cb6bb6f820f 446 SUPERFAMILY SSF52413 317 437 2.49E-30 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD11_RS20600 ccb888dbd90b96e875f97cb6bb6f820f 446 SMART SM00984 327 428 1.4E-38 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD11_RS20600 ccb888dbd90b96e875f97cb6bb6f820f 446 Gene3D G3DSA:3.40.50.720 4 212 1.6E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20600 ccb888dbd90b96e875f97cb6bb6f820f 446 PIRSF PIRSF000124 3 443 2.2E-108 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMD11_RS20600 ccb888dbd90b96e875f97cb6bb6f820f 446 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 191 4.6E-54 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD11_RS20600 ccb888dbd90b96e875f97cb6bb6f820f 446 SUPERFAMILY SSF48179 209 308 4.25E-26 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS20600 ccb888dbd90b96e875f97cb6bb6f820f 446 PIRSF PIRSF500134 3 446 1.6E-148 T 06-07-2017 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 SUPERFAMILY SSF56784 508 761 5.17E-60 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 SUPERFAMILY SSF56784 352 372 5.17E-60 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 SUPERFAMILY SSF81660 360 563 2.13E-53 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 630 737 3.1E-31 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 115 376 8.2E-42 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 Pfam PF00122 E1-E2 ATPase 113 345 3.6E-66 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 Pfam PF00690 Cation transporter/ATPase, N-terminus 29 93 2.3E-11 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 Gene3D G3DSA:3.40.50.1000 559 612 2.5E-4 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 Gene3D G3DSA:3.40.1110.10 344 558 1.3E-60 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 Pfam PF13246 Cation transport ATPase (P-type) 405 493 5.2E-20 T 06-07-2017 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 Gene3D G3DSA:1.20.1110.10 625 927 3.9E-104 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 Gene3D G3DSA:1.20.1110.10 79 140 3.9E-104 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 SMART SM00831 26 99 3.5E-17 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 SUPERFAMILY SSF81665 706 928 4.45E-111 T 06-07-2017 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 SUPERFAMILY SSF81665 255 348 4.45E-111 T 06-07-2017 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 SUPERFAMILY SSF81665 28 146 4.45E-111 T 06-07-2017 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 Pfam PF00689 Cation transporting ATPase, C-terminus 742 924 2.2E-49 T 06-07-2017 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 356 362 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 SUPERFAMILY SSF81653 145 253 1.83E-28 T 06-07-2017 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 Gene3D G3DSA:2.70.150.10 43 78 3.8E-38 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 Gene3D G3DSA:2.70.150.10 141 253 3.8E-38 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 511 529 2.5E-17 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 628 644 2.5E-17 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 656 672 2.5E-17 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 688 713 2.5E-17 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 551 562 1.0E-37 T 06-07-2017 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 193 207 1.0E-37 T 06-07-2017 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 656 675 1.0E-37 T 06-07-2017 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 680 692 1.0E-37 T 06-07-2017 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 354 368 1.0E-37 T 06-07-2017 SMD11_RS05000 bf59263739da78887b000ff13b1b134f 938 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 573 583 1.0E-37 T 06-07-2017 SMD11_RS31515 78568d8107f4f54e46a65ebb35ca801e 321 Gene3D G3DSA:2.60.120.330 5 317 7.9E-75 T 06-07-2017 IPR027443 Isopenicillin N synthase-like SMD11_RS31515 78568d8107f4f54e46a65ebb35ca801e 321 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 197 282 4.0E-12 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 SMD11_RS31515 78568d8107f4f54e46a65ebb35ca801e 321 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 6 131 2.2E-26 T 06-07-2017 IPR026992 Non-haem dioxygenase N-terminal domain SMD11_RS31515 78568d8107f4f54e46a65ebb35ca801e 321 SUPERFAMILY SSF51197 4 299 3.3E-68 T 06-07-2017 SMD11_RS23745 67d99efa91161b20ae899086cb8a0ba9 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 1.3E-20 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase SMD11_RS23745 67d99efa91161b20ae899086cb8a0ba9 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 1.3E-20 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase SMD11_RS23745 67d99efa91161b20ae899086cb8a0ba9 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 1.3E-20 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase SMD11_RS23745 67d99efa91161b20ae899086cb8a0ba9 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 1.3E-20 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase SMD11_RS23745 67d99efa91161b20ae899086cb8a0ba9 285 SUPERFAMILY SSF55920 6 284 9.68E-87 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS23745 67d99efa91161b20ae899086cb8a0ba9 285 Gene3D G3DSA:3.90.230.10 41 284 3.0E-96 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS23745 67d99efa91161b20ae899086cb8a0ba9 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 40.06 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 SMD11_RS23745 67d99efa91161b20ae899086cb8a0ba9 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 SMD11_RS23745 67d99efa91161b20ae899086cb8a0ba9 285 Pfam PF00557 Metallopeptidase family M24 48 276 3.0E-53 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS23745 67d99efa91161b20ae899086cb8a0ba9 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 41 283 4.1E-90 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 SMD11_RS33225 4bdf4e7876bd4a2470cf00f3ab31a859 399 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 154 396 6.9E-48 T 06-07-2017 SMD11_RS33225 4bdf4e7876bd4a2470cf00f3ab31a859 399 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 276 284 4.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33225 4bdf4e7876bd4a2470cf00f3ab31a859 399 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 296 315 4.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33225 4bdf4e7876bd4a2470cf00f3ab31a859 399 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 283 311 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS33225 4bdf4e7876bd4a2470cf00f3ab31a859 399 Gene3D G3DSA:3.40.50.720 144 398 1.6E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33225 4bdf4e7876bd4a2470cf00f3ab31a859 399 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 296 315 1.1E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33225 4bdf4e7876bd4a2470cf00f3ab31a859 399 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 270 286 1.1E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33225 4bdf4e7876bd4a2470cf00f3ab31a859 399 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 317 334 1.1E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33225 4bdf4e7876bd4a2470cf00f3ab31a859 399 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 360 380 1.1E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33225 4bdf4e7876bd4a2470cf00f3ab31a859 399 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 166 1.1E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33225 4bdf4e7876bd4a2470cf00f3ab31a859 399 SUPERFAMILY SSF51735 147 398 1.97E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS15560 c619dc092ee84130d40f2bd53ff0bd60 308 SUPERFAMILY SSF56300 41 302 6.94E-25 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS15560 c619dc092ee84130d40f2bd53ff0bd60 308 Pfam PF00149 Calcineurin-like phosphoesterase 47 239 2.1E-7 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 SMD11_RS15560 c619dc092ee84130d40f2bd53ff0bd60 308 Gene3D G3DSA:3.60.21.10 149 254 8.5E-13 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS15560 c619dc092ee84130d40f2bd53ff0bd60 308 Gene3D G3DSA:3.60.21.10 46 116 8.5E-13 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS32170 4e7638ca693fd60fc9cc9565927767f6 510 Pfam PF13520 Amino acid permease 5 403 3.0E-37 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS32170 4e7638ca693fd60fc9cc9565927767f6 510 PIRSF PIRSF006060 1 434 4.1E-54 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS00850 1cba1c0ffdd0cd236f4781ea62169ac5 420 Gene3D G3DSA:1.10.630.10 18 418 1.2E-104 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00850 1cba1c0ffdd0cd236f4781ea62169ac5 420 PRINTS PR00359 B-class P450 signature 212 234 1.8E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00850 1cba1c0ffdd0cd236f4781ea62169ac5 420 PRINTS PR00359 B-class P450 signature 95 106 1.8E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00850 1cba1c0ffdd0cd236f4781ea62169ac5 420 PRINTS PR00359 B-class P450 signature 338 353 1.8E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00850 1cba1c0ffdd0cd236f4781ea62169ac5 420 PRINTS PR00359 B-class P450 signature 293 304 1.8E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00850 1cba1c0ffdd0cd236f4781ea62169ac5 420 PRINTS PR00359 B-class P450 signature 310 337 1.8E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00850 1cba1c0ffdd0cd236f4781ea62169ac5 420 PRINTS PR00359 B-class P450 signature 360 369 1.8E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00850 1cba1c0ffdd0cd236f4781ea62169ac5 420 PRINTS PR00359 B-class P450 signature 141 157 1.8E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00850 1cba1c0ffdd0cd236f4781ea62169ac5 420 PRINTS PR00359 B-class P450 signature 369 380 1.8E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00850 1cba1c0ffdd0cd236f4781ea62169ac5 420 PRINTS PR00359 B-class P450 signature 158 173 1.8E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00850 1cba1c0ffdd0cd236f4781ea62169ac5 420 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 362 371 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS00850 1cba1c0ffdd0cd236f4781ea62169ac5 420 SUPERFAMILY SSF48264 15 418 6.42E-86 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00850 1cba1c0ffdd0cd236f4781ea62169ac5 420 Pfam PF00067 Cytochrome P450 78 391 5.2E-26 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS26510 b2aeb914b8828003f42719476c7ceef8 497 PIRSF PIRSF018077 4 494 6.6E-219 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 SMD11_RS26510 b2aeb914b8828003f42719476c7ceef8 497 Pfam PF03136 Pup-ligase protein 1 451 2.3E-191 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 SMD11_RS26510 b2aeb914b8828003f42719476c7ceef8 497 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 1 484 6.8E-247 T 06-07-2017 IPR022366 Pup deamidase GO:0008233|GO:0016811 SMD11_RS21360 78a135d4b62772b2daf2831f88c43cb4 441 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 231 423 2.4E-25 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS21360 78a135d4b62772b2daf2831f88c43cb4 441 SUPERFAMILY SSF52266 222 428 2.75E-46 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS21360 78a135d4b62772b2daf2831f88c43cb4 441 Gene3D G3DSA:3.40.50.1110 229 429 7.4E-35 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS20945 a8ea938cd35938118d33d1f6ec00a572 304 Pfam PF02687 FtsX-like permease family 185 303 2.5E-11 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 SMD11_RS20945 a8ea938cd35938118d33d1f6ec00a572 304 PIRSF PIRSF003097 1 304 3.8E-75 T 06-07-2017 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 SMD11_RS00290 2b0b679ebadcb6eec8c80caf84e30577 523 Pfam PF13560 Helix-turn-helix domain 27 77 1.4E-7 T 06-07-2017 SMD11_RS00290 2b0b679ebadcb6eec8c80caf84e30577 523 Gene3D G3DSA:1.10.260.40 27 83 8.3E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS00290 2b0b679ebadcb6eec8c80caf84e30577 523 SUPERFAMILY SSF47413 27 72 6.0E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS13315 e3ac5fa8e09b853f30aa3a844a05deea 426 Gene3D G3DSA:3.30.565.10 319 422 7.4E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS13315 e3ac5fa8e09b853f30aa3a844a05deea 426 SUPERFAMILY SSF55874 310 420 5.11E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS13315 e3ac5fa8e09b853f30aa3a844a05deea 426 Pfam PF13581 Histidine kinase-like ATPase domain 322 387 9.7E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS13315 e3ac5fa8e09b853f30aa3a844a05deea 426 Pfam PF04024 PspC domain 18 73 1.2E-14 T 06-07-2017 IPR007168 Phage shock protein, PspC, N-terminal SMD11_RS06675 75c16bef5bdeb678c7f221d2df3b5df2 147 Gene3D G3DSA:1.10.10.10 2 132 4.4E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06675 75c16bef5bdeb678c7f221d2df3b5df2 147 Pfam PF02082 Transcriptional regulator 2 83 2.3E-15 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type SMD11_RS06675 75c16bef5bdeb678c7f221d2df3b5df2 147 SUPERFAMILY SSF46785 2 132 4.29E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06675 75c16bef5bdeb678c7f221d2df3b5df2 147 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 130 1.2E-23 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type SMD11_RS19425 38759c3fd78da01c54f720ebf7e7a7ad 383 Gene3D G3DSA:3.40.47.10 199 226 1.7E-7 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS19425 38759c3fd78da01c54f720ebf7e7a7ad 383 Gene3D G3DSA:3.40.47.10 13 115 1.7E-7 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS19425 38759c3fd78da01c54f720ebf7e7a7ad 383 SUPERFAMILY SSF53901 7 229 1.51E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS19425 38759c3fd78da01c54f720ebf7e7a7ad 383 SUPERFAMILY SSF53901 253 368 9.88E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS19425 38759c3fd78da01c54f720ebf7e7a7ad 383 PIRSF PIRSF000429 4 371 5.5E-21 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS19425 38759c3fd78da01c54f720ebf7e7a7ad 383 Gene3D G3DSA:3.40.47.10 147 183 2.4E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS19425 38759c3fd78da01c54f720ebf7e7a7ad 383 Gene3D G3DSA:3.40.47.10 247 334 2.4E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS14440 44060c0547bcbdff207b2eaf76feab68 344 Gene3D G3DSA:3.40.50.1980 62 204 3.3E-11 T 06-07-2017 SMD11_RS14440 44060c0547bcbdff207b2eaf76feab68 344 Pfam PF01497 Periplasmic binding protein 65 317 1.6E-29 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD11_RS14440 44060c0547bcbdff207b2eaf76feab68 344 Gene3D G3DSA:3.40.50.1980 208 338 1.0E-28 T 06-07-2017 SMD11_RS14440 44060c0547bcbdff207b2eaf76feab68 344 SUPERFAMILY SSF53807 62 338 6.67E-43 T 06-07-2017 SMD11_RS30200 88f7445a15fc388641a8c41fbfcd526a 336 Pfam PF03640 Secreted repeat of unknown function 282 324 7.6E-14 T 06-07-2017 IPR005297 Lipoprotein repeat SMD11_RS30200 88f7445a15fc388641a8c41fbfcd526a 336 Pfam PF03640 Secreted repeat of unknown function 138 178 7.5E-16 T 06-07-2017 IPR005297 Lipoprotein repeat SMD11_RS30200 88f7445a15fc388641a8c41fbfcd526a 336 Pfam PF03640 Secreted repeat of unknown function 83 120 1.7E-13 T 06-07-2017 IPR005297 Lipoprotein repeat SMD11_RS30200 88f7445a15fc388641a8c41fbfcd526a 336 Pfam PF03640 Secreted repeat of unknown function 224 266 1.6E-13 T 06-07-2017 IPR005297 Lipoprotein repeat SMD11_RS08975 bc96d12c5580b76a8e71c8ccd1bed942 268 SMART SM01232 124 212 4.3E-21 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD11_RS08975 bc96d12c5580b76a8e71c8ccd1bed942 268 SMART SM00898 2 110 2.7E-23 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD11_RS08975 bc96d12c5580b76a8e71c8ccd1bed942 268 Gene3D G3DSA:3.20.190.10 2 120 5.7E-16 T 06-07-2017 SMD11_RS08975 bc96d12c5580b76a8e71c8ccd1bed942 268 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 124 186 6.6E-9 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD11_RS08975 bc96d12c5580b76a8e71c8ccd1bed942 268 Pfam PF06827 Zinc finger found in FPG and IleRS 230 260 1.6E-4 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 SMD11_RS08975 bc96d12c5580b76a8e71c8ccd1bed942 268 SUPERFAMILY SSF46946 123 188 1.35E-17 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMD11_RS08975 bc96d12c5580b76a8e71c8ccd1bed942 268 Gene3D G3DSA:1.10.8.50 124 260 2.5E-36 T 06-07-2017 SMD11_RS08975 bc96d12c5580b76a8e71c8ccd1bed942 268 SUPERFAMILY SSF57716 214 260 4.28E-11 T 06-07-2017 SMD11_RS08975 bc96d12c5580b76a8e71c8ccd1bed942 268 SUPERFAMILY SSF81624 2 125 1.01E-26 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD11_RS08975 bc96d12c5580b76a8e71c8ccd1bed942 268 ProSitePatterns PS01242 Zinc finger FPG-type signature. 231 259 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 SMD11_RS08975 bc96d12c5580b76a8e71c8ccd1bed942 268 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 83 1.3E-8 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD11_RS18735 af9c6bf1d09c3c0be32e4b727616fbb6 287 Hamap MF_00188 Protease HtpX [htpX]. 7 282 27.92 T 06-07-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 SMD11_RS18735 af9c6bf1d09c3c0be32e4b727616fbb6 287 Pfam PF01435 Peptidase family M48 69 282 7.3E-36 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMD11_RS18735 af9c6bf1d09c3c0be32e4b727616fbb6 287 Gene3D G3DSA:3.30.2010.10 59 149 1.4E-30 T 06-07-2017 SMD11_RS33505 70d8fc6f947066ced66c485c4def5acd 136 Hamap MF_01255 L-ectoine synthase [ectC]. 1 129 37.47 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS33505 70d8fc6f947066ced66c485c4def5acd 136 Gene3D G3DSA:2.60.120.10 21 112 3.2E-11 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS33505 70d8fc6f947066ced66c485c4def5acd 136 SUPERFAMILY SSF51182 19 132 1.34E-17 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS33505 70d8fc6f947066ced66c485c4def5acd 136 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 119 2.0E-56 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS33505 70d8fc6f947066ced66c485c4def5acd 136 Pfam PF06339 Ectoine synthase 2 127 5.7E-53 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS25850 3d9f977bb824628e081b440942c644a6 120 SUPERFAMILY SSF56399 1 112 1.35E-16 T 06-07-2017 SMD11_RS25850 3d9f977bb824628e081b440942c644a6 120 Pfam PF06108 Protein of unknown function (DUF952) 6 100 7.0E-18 T 06-07-2017 IPR009297 Protein of unknown function DUF952 SMD11_RS12545 8ff9439308ea813417d1453cd7d322e1 404 Pfam PF10979 Protein of unknown function (DUF2786) 177 216 5.0E-16 T 06-07-2017 IPR024498 Domain of unknown function DUF2786 SMD11_RS12545 8ff9439308ea813417d1453cd7d322e1 404 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 179 384 7.0E-41 T 06-07-2017 SMD11_RS34030 3bffdff17e90340244907cc5a6b9571b 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 158 182 5.7E-7 T 06-07-2017 SMD11_RS34030 3bffdff17e90340244907cc5a6b9571b 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 128 148 5.7E-7 T 06-07-2017 SMD11_RS34030 3bffdff17e90340244907cc5a6b9571b 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 37 61 5.7E-7 T 06-07-2017 SMD11_RS34030 3bffdff17e90340244907cc5a6b9571b 492 SUPERFAMILY SSF103473 273 490 2.27E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS34030 3bffdff17e90340244907cc5a6b9571b 492 SUPERFAMILY SSF103473 11 221 2.27E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS34030 3bffdff17e90340244907cc5a6b9571b 492 Pfam PF07690 Major Facilitator Superfamily 41 437 2.3E-45 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS34030 3bffdff17e90340244907cc5a6b9571b 492 Gene3D G3DSA:1.20.1250.20 297 490 1.1E-12 T 06-07-2017 SMD11_RS34030 3bffdff17e90340244907cc5a6b9571b 492 Gene3D G3DSA:1.20.1250.20 35 223 1.8E-29 T 06-07-2017 SMD11_RS20740 02dba6e1b5d9055a4bc7f186ae13f807 662 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 138 472 2.2E-89 T 06-07-2017 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 SMD11_RS20740 02dba6e1b5d9055a4bc7f186ae13f807 662 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 22 111 2.2E-17 T 06-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SMD11_RS20740 02dba6e1b5d9055a4bc7f186ae13f807 662 SUPERFAMILY SSF55804 514 659 6.93E-36 T 06-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SMD11_RS20740 02dba6e1b5d9055a4bc7f186ae13f807 662 Gene3D G3DSA:3.40.930.10 517 658 1.9E-41 T 06-07-2017 IPR002178 PTS EIIA type-2 domain SMD11_RS20740 02dba6e1b5d9055a4bc7f186ae13f807 662 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 528 645 7.9E-35 T 06-07-2017 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 SMD11_RS20740 02dba6e1b5d9055a4bc7f186ae13f807 662 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 563 579 - T 06-07-2017 IPR002178 PTS EIIA type-2 domain SMD11_RS20740 02dba6e1b5d9055a4bc7f186ae13f807 662 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 22 103 1.9E-33 T 06-07-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 SMD11_RS20740 02dba6e1b5d9055a4bc7f186ae13f807 662 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 520 657 2.2E-32 T 06-07-2017 IPR002178 PTS EIIA type-2 domain SMD11_RS20740 02dba6e1b5d9055a4bc7f186ae13f807 662 SUPERFAMILY SSF52794 19 114 2.62E-37 T 06-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SMD11_RS20740 02dba6e1b5d9055a4bc7f186ae13f807 662 Gene3D G3DSA:3.40.50.2300 19 114 3.0E-41 T 06-07-2017 SMD11_RS29445 db985c1f70c66c65a8ff1d46df936219 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 4.0E-29 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS29445 db985c1f70c66c65a8ff1d46df936219 68 PRINTS PR00050 Cold shock protein signature 4 19 6.8E-16 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS29445 db985c1f70c66c65a8ff1d46df936219 68 PRINTS PR00050 Cold shock protein signature 40 58 6.8E-16 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS29445 db985c1f70c66c65a8ff1d46df936219 68 PRINTS PR00050 Cold shock protein signature 25 34 6.8E-16 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS29445 db985c1f70c66c65a8ff1d46df936219 68 PIRSF PIRSF002599 1 68 4.5E-24 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 SMD11_RS29445 db985c1f70c66c65a8ff1d46df936219 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site SMD11_RS29445 db985c1f70c66c65a8ff1d46df936219 68 Gene3D G3DSA:2.40.50.140 1 65 5.9E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS29445 db985c1f70c66c65a8ff1d46df936219 68 SUPERFAMILY SSF50249 1 66 1.03E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS29445 db985c1f70c66c65a8ff1d46df936219 68 SMART SM00357 3 67 3.9E-27 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 SMD11_RS33500 ca7b51eb0db259c7ab1f1da41af5f993 338 Gene3D G3DSA:3.90.1530.10 21 107 2.5E-11 T 06-07-2017 SMD11_RS33500 ca7b51eb0db259c7ab1f1da41af5f993 338 SUPERFAMILY SSF110849 23 107 5.41E-12 T 06-07-2017 IPR003115 ParB/Sulfiredoxin SMD11_RS33500 ca7b51eb0db259c7ab1f1da41af5f993 338 Pfam PF02195 ParB-like nuclease domain 24 105 1.3E-9 T 06-07-2017 IPR003115 ParB/Sulfiredoxin SMD11_RS33500 ca7b51eb0db259c7ab1f1da41af5f993 338 SMART SM00470 22 106 1.4E-10 T 06-07-2017 IPR003115 ParB/Sulfiredoxin SMD11_RS32995 060d02a4a253166ab37956c02a06bd11 183 Gene3D G3DSA:3.40.50.300 5 183 5.6E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS32995 060d02a4a253166ab37956c02a06bd11 183 SUPERFAMILY SSF52540 9 179 7.68E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS32995 060d02a4a253166ab37956c02a06bd11 183 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 8 175 2.1E-58 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 SMD11_RS32995 060d02a4a253166ab37956c02a06bd11 183 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 7 181 33.345 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 SMD11_RS32995 060d02a4a253166ab37956c02a06bd11 183 Pfam PF01583 Adenylylsulphate kinase 9 164 7.5E-59 T 06-07-2017 SMD11_RS09910 12ca2bb05c7087757aab457ff60921ca 193 Gene3D G3DSA:3.40.50.300 12 187 1.3E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09910 12ca2bb05c7087757aab457ff60921ca 193 Pfam PF03029 Conserved hypothetical ATP binding protein 21 188 2.5E-27 T 06-07-2017 IPR004130 GPN-loop GTPase SMD11_RS09910 12ca2bb05c7087757aab457ff60921ca 193 SUPERFAMILY SSF52540 16 187 1.62E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29790 bd05fb73435ee7ee81da04fabf618126 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 53 7.6E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS29790 bd05fb73435ee7ee81da04fabf618126 221 SUPERFAMILY SSF46689 17 84 2.0E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS29790 bd05fb73435ee7ee81da04fabf618126 221 Gene3D G3DSA:1.10.357.10 15 218 1.1E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS22500 a9d3d71a963668f545dc8b3f70ef30c5 201 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 10 200 30.191 T 06-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 SMD11_RS22500 a9d3d71a963668f545dc8b3f70ef30c5 201 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 14 199 2.6E-52 T 06-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 SMD11_RS22500 a9d3d71a963668f545dc8b3f70ef30c5 201 SUPERFAMILY SSF52374 10 201 4.38E-51 T 06-07-2017 SMD11_RS22500 a9d3d71a963668f545dc8b3f70ef30c5 201 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 13 76 2.4E-10 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SMD11_RS22500 a9d3d71a963668f545dc8b3f70ef30c5 201 Gene3D G3DSA:3.40.50.620 10 200 1.9E-64 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS22500 a9d3d71a963668f545dc8b3f70ef30c5 201 Pfam PF01467 Cytidylyltransferase-like 14 174 4.5E-29 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SMD11_RS07770 24b2b995e68e6bd34d3293091cd4eab2 255 Gene3D G3DSA:3.40.50.720 2 247 1.9E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS07770 24b2b995e68e6bd34d3293091cd4eab2 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 9.0E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS07770 24b2b995e68e6bd34d3293091cd4eab2 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 9.0E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS07770 24b2b995e68e6bd34d3293091cd4eab2 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 9.0E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS07770 24b2b995e68e6bd34d3293091cd4eab2 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 246 1.9E-60 T 06-07-2017 SMD11_RS07770 24b2b995e68e6bd34d3293091cd4eab2 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 187 0.0011 T 06-07-2017 SMD11_RS07770 24b2b995e68e6bd34d3293091cd4eab2 255 SUPERFAMILY SSF51735 8 246 4.18E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS07770 24b2b995e68e6bd34d3293091cd4eab2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.8E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS07770 24b2b995e68e6bd34d3293091cd4eab2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.8E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS07770 24b2b995e68e6bd34d3293091cd4eab2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 3.8E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS07770 24b2b995e68e6bd34d3293091cd4eab2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.8E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS07770 24b2b995e68e6bd34d3293091cd4eab2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.8E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS07770 24b2b995e68e6bd34d3293091cd4eab2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.8E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS07770 24b2b995e68e6bd34d3293091cd4eab2 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS14750 b94770701ec786a0c837dd123fd09a99 218 Gene3D G3DSA:1.10.10.10 156 214 6.8E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14750 b94770701ec786a0c837dd123fd09a99 218 SUPERFAMILY SSF52172 2 133 4.7E-34 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS14750 b94770701ec786a0c837dd123fd09a99 218 SMART SM00421 152 209 9.8E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14750 b94770701ec786a0c837dd123fd09a99 218 SMART SM00448 2 115 3.1E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS14750 b94770701ec786a0c837dd123fd09a99 218 Gene3D G3DSA:3.40.50.2300 2 155 1.1E-39 T 06-07-2017 SMD11_RS14750 b94770701ec786a0c837dd123fd09a99 218 SUPERFAMILY SSF46894 142 215 3.03E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS14750 b94770701ec786a0c837dd123fd09a99 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 2.9E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14750 b94770701ec786a0c837dd123fd09a99 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 4.4E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14750 b94770701ec786a0c837dd123fd09a99 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 4.4E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14750 b94770701ec786a0c837dd123fd09a99 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 4.4E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14750 b94770701ec786a0c837dd123fd09a99 218 Pfam PF00072 Response regulator receiver domain 4 114 3.5E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS26285 7bdccbaa6df9cef51d22d196108e11bb 181 Gene3D G3DSA:3.90.79.10 12 176 1.1E-52 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS26285 7bdccbaa6df9cef51d22d196108e11bb 181 PIRSF PIRSF017340 2 179 1.7E-76 T 06-07-2017 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 SMD11_RS26285 7bdccbaa6df9cef51d22d196108e11bb 181 ProSitePatterns PS00893 Nudix box signature. 78 99 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD11_RS26285 7bdccbaa6df9cef51d22d196108e11bb 181 SUPERFAMILY SSF55811 15 176 7.99E-32 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS26285 7bdccbaa6df9cef51d22d196108e11bb 181 Pfam PF00293 NUDIX domain 41 157 1.1E-15 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS12885 2182165c42f2c81cd2d3a7804897618e 265 Gene3D G3DSA:1.10.10.60 4 64 2.0E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS12885 2182165c42f2c81cd2d3a7804897618e 265 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 56 3.8E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS12885 2182165c42f2c81cd2d3a7804897618e 265 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 53 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD11_RS12885 2182165c42f2c81cd2d3a7804897618e 265 Gene3D G3DSA:1.10.357.10 70 209 1.4E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS12885 2182165c42f2c81cd2d3a7804897618e 265 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 5.6E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS12885 2182165c42f2c81cd2d3a7804897618e 265 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 5.6E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS12885 2182165c42f2c81cd2d3a7804897618e 265 PRINTS PR00400 Tetracycline repressor protein signature 132 151 1.0E-24 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD11_RS12885 2182165c42f2c81cd2d3a7804897618e 265 PRINTS PR00400 Tetracycline repressor protein signature 192 206 1.0E-24 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD11_RS12885 2182165c42f2c81cd2d3a7804897618e 265 PRINTS PR00400 Tetracycline repressor protein signature 76 95 1.0E-24 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD11_RS12885 2182165c42f2c81cd2d3a7804897618e 265 PRINTS PR00400 Tetracycline repressor protein signature 22 45 1.0E-24 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD11_RS12885 2182165c42f2c81cd2d3a7804897618e 265 PRINTS PR00400 Tetracycline repressor protein signature 96 119 1.0E-24 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 SMD11_RS12885 2182165c42f2c81cd2d3a7804897618e 265 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 73 209 1.9E-25 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD11_RS12885 2182165c42f2c81cd2d3a7804897618e 265 SUPERFAMILY SSF46689 5 65 3.33E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS12885 2182165c42f2c81cd2d3a7804897618e 265 SUPERFAMILY SSF48498 73 209 1.22E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS05425 84a0a3e447affe46e310915f85ebf282 323 SUPERFAMILY SSF52317 5 194 5.73E-52 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS05425 84a0a3e447affe46e310915f85ebf282 323 SUPERFAMILY SSF46689 265 318 6.15E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS05425 84a0a3e447affe46e310915f85ebf282 323 Pfam PF01965 DJ-1/PfpI family 6 174 9.4E-29 T 06-07-2017 IPR002818 DJ-1/PfpI SMD11_RS05425 84a0a3e447affe46e310915f85ebf282 323 Pfam PF12833 Helix-turn-helix domain 235 314 1.2E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS05425 84a0a3e447affe46e310915f85ebf282 323 SMART SM00342 229 312 4.3E-30 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS05425 84a0a3e447affe46e310915f85ebf282 323 SUPERFAMILY SSF46689 213 262 5.3E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS05425 84a0a3e447affe46e310915f85ebf282 323 Gene3D G3DSA:1.10.10.60 219 266 2.2E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS05425 84a0a3e447affe46e310915f85ebf282 323 Gene3D G3DSA:3.40.50.880 6 218 6.7E-62 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS05425 84a0a3e447affe46e310915f85ebf282 323 Gene3D G3DSA:1.10.10.60 267 317 4.6E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS15035 fd0402ec2acddea1874699871b97fb65 80 PRINTS PR00974 Ribosomal protein S18 family signature 51 65 5.1E-18 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS15035 fd0402ec2acddea1874699871b97fb65 80 PRINTS PR00974 Ribosomal protein S18 family signature 43 50 5.1E-18 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS15035 fd0402ec2acddea1874699871b97fb65 80 PRINTS PR00974 Ribosomal protein S18 family signature 33 43 5.1E-18 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS15035 fd0402ec2acddea1874699871b97fb65 80 PRINTS PR00974 Ribosomal protein S18 family signature 65 75 5.1E-18 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS15035 fd0402ec2acddea1874699871b97fb65 80 SUPERFAMILY SSF46911 5 77 1.19E-26 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS15035 fd0402ec2acddea1874699871b97fb65 80 Gene3D G3DSA:4.10.640.10 14 76 4.6E-30 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS15035 fd0402ec2acddea1874699871b97fb65 80 ProSitePatterns PS00057 Ribosomal protein S18 signature. 26 49 - T 06-07-2017 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS15035 fd0402ec2acddea1874699871b97fb65 80 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 75 5.0E-10 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS15035 fd0402ec2acddea1874699871b97fb65 80 TIGRFAM TIGR00165 S18: ribosomal protein bS18 20 75 1.1E-23 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS15035 fd0402ec2acddea1874699871b97fb65 80 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 4 78 20.237 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS15035 fd0402ec2acddea1874699871b97fb65 80 Pfam PF01084 Ribosomal protein S18 23 73 4.3E-25 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS21140 b2c8da303014f9842272667cf8fdf283 420 SUPERFAMILY SSF52540 16 255 1.22E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21140 b2c8da303014f9842272667cf8fdf283 420 Pfam PF00005 ABC transporter 34 179 3.3E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS21140 b2c8da303014f9842272667cf8fdf283 420 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 32 380 3.0E-103 T 06-07-2017 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 SMD11_RS21140 b2c8da303014f9842272667cf8fdf283 420 Gene3D G3DSA:3.10.580.10 265 378 7.8E-8 T 06-07-2017 SMD11_RS21140 b2c8da303014f9842272667cf8fdf283 420 SMART SM00382 42 238 9.8E-20 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS21140 b2c8da303014f9842272667cf8fdf283 420 Gene3D G3DSA:3.40.50.300 10 252 1.1E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21140 b2c8da303014f9842272667cf8fdf283 420 SUPERFAMILY SSF54631 266 387 8.85E-10 T 06-07-2017 SMD11_RS21140 b2c8da303014f9842272667cf8fdf283 420 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS10675 c2f72a9472cd9f227e3c8e8c429015e2 146 Gene3D G3DSA:3.10.180.10 1 136 3.0E-36 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS10675 c2f72a9472cd9f227e3c8e8c429015e2 146 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 136 2.9E-43 T 06-07-2017 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|Reactome: R-HSA-71032 SMD11_RS10675 c2f72a9472cd9f227e3c8e8c429015e2 146 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 122 1.4E-20 T 06-07-2017 SMD11_RS10675 c2f72a9472cd9f227e3c8e8c429015e2 146 SUPERFAMILY SSF54593 1 138 7.98E-34 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS20920 ecc274e945aa08195b2eb2923669ec85 445 Gene3D G3DSA:1.10.510.10 73 280 8.7E-45 T 06-07-2017 SMD11_RS20920 ecc274e945aa08195b2eb2923669ec85 445 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 126 138 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS20920 ecc274e945aa08195b2eb2923669ec85 445 SUPERFAMILY SSF56112 6 281 1.23E-63 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS20920 ecc274e945aa08195b2eb2923669ec85 445 Pfam PF00069 Protein kinase domain 9 279 1.6E-43 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS20920 ecc274e945aa08195b2eb2923669ec85 445 Gene3D G3DSA:3.30.200.20 4 72 1.9E-16 T 06-07-2017 SMD11_RS20920 ecc274e945aa08195b2eb2923669ec85 445 SMART SM00220 9 287 6.8E-61 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS10620 9c3ccf4b0da2fef302b4764ea357b91f 98 Pfam PF01910 Thiamine-binding protein 3 92 4.4E-29 T 06-07-2017 IPR002767 Thiamine-binding protein SMD11_RS10620 9c3ccf4b0da2fef302b4764ea357b91f 98 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 1 94 2.0E-18 T 06-07-2017 IPR002767 Thiamine-binding protein SMD11_RS10620 9c3ccf4b0da2fef302b4764ea357b91f 98 Gene3D G3DSA:3.30.70.930 1 92 7.4E-35 T 06-07-2017 IPR029756 MTH1187/YkoF-like SMD11_RS10620 9c3ccf4b0da2fef302b4764ea357b91f 98 SUPERFAMILY SSF89957 1 95 1.83E-29 T 06-07-2017 IPR029756 MTH1187/YkoF-like SMD11_RS01225 adb01ca77783e8fc7dc58cc28e0cfd5b 194 Pfam PF02342 TerD domain 14 173 2.6E-18 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS01225 adb01ca77783e8fc7dc58cc28e0cfd5b 194 Gene3D G3DSA:2.60.60.30 15 188 1.1E-33 T 06-07-2017 SMD11_RS19465 bb36733fda1ae1cb840f6b21c1e64537 374 Gene3D G3DSA:3.20.20.30 1 367 3.1E-78 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS19465 bb36733fda1ae1cb840f6b21c1e64537 374 Pfam PF00296 Luciferase-like monooxygenase 2 329 5.2E-47 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS19465 bb36733fda1ae1cb840f6b21c1e64537 374 SUPERFAMILY SSF51679 1 358 2.49E-67 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 SUPERFAMILY SSF55781 459 640 2.4E-11 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 Pfam PF13185 GAF domain 309 444 2.0E-11 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 Pfam PF13185 GAF domain 508 633 1.8E-7 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 Pfam PF13581 Histidine kinase-like ATPase domain 28 139 4.6E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 690 880 1.6E-41 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 SMART SM00331 663 880 1.3E-65 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 SMART SM00065 474 642 0.026 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 SMART SM00065 309 453 5.7E-12 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 Gene3D G3DSA:3.30.450.40 308 450 3.8E-20 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 SUPERFAMILY SSF55785 170 264 2.44E-13 T 06-07-2017 IPR000014 PAS domain SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 Gene3D G3DSA:3.30.450.20 170 260 4.6E-10 T 06-07-2017 SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 SUPERFAMILY SSF81606 672 879 1.07E-5 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 Pfam PF00989 PAS fold 170 209 1.5E-6 T 06-07-2017 IPR013767 PAS fold GO:0006355 SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 SUPERFAMILY SSF55781 310 448 9.38E-20 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 Gene3D G3DSA:3.30.450.40 463 640 5.9E-21 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS09030 35490fa99abba57064071e1f90d1283a 886 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 170 268 2.7E-6 T 06-07-2017 IPR000014 PAS domain SMD11_RS02270 4a018d1c5f04444df5f0b84a414bf79e 109 SUPERFAMILY SSF46785 12 95 3.47E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02270 4a018d1c5f04444df5f0b84a414bf79e 109 Gene3D G3DSA:1.10.10.10 4 92 1.0E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02270 4a018d1c5f04444df5f0b84a414bf79e 109 Pfam PF13601 Winged helix DNA-binding domain 14 92 1.3E-23 T 06-07-2017 IPR027395 Winged helix DNA-binding domain SMD11_RS27685 c0a2b2f51b1a9ac2543d869d877479be 219 Gene3D G3DSA:3.30.70.270 32 183 4.1E-35 T 06-07-2017 SMD11_RS27685 c0a2b2f51b1a9ac2543d869d877479be 219 SMART SM00267 21 188 4.2E-30 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS27685 c0a2b2f51b1a9ac2543d869d877479be 219 SUPERFAMILY SSF55073 36 183 1.43E-30 T 06-07-2017 IPR029787 Nucleotide cyclase SMD11_RS27685 c0a2b2f51b1a9ac2543d869d877479be 219 Pfam PF00990 Diguanylate cyclase, GGDEF domain 31 182 2.0E-30 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS27685 c0a2b2f51b1a9ac2543d869d877479be 219 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 30 183 7.0E-26 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS04640 ccbe46d1e92af22bbac075c6e48ab958 244 SUPERFAMILY SSF54637 6 86 3.26E-9 T 06-07-2017 IPR029069 HotDog domain SMD11_RS04640 ccbe46d1e92af22bbac075c6e48ab958 244 SUPERFAMILY SSF54637 98 242 2.07E-10 T 06-07-2017 IPR029069 HotDog domain SMD11_RS04640 ccbe46d1e92af22bbac075c6e48ab958 244 Gene3D G3DSA:3.10.129.10 6 78 3.4E-5 T 06-07-2017 IPR029069 HotDog domain SMD11_RS04640 ccbe46d1e92af22bbac075c6e48ab958 244 Pfam PF13622 Thioesterase-like superfamily 12 240 3.2E-31 T 06-07-2017 SMD11_RS09545 e27b1d78320c9a60f50a30f43653138d 542 SUPERFAMILY SSF54211 2 170 9.86E-38 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS09545 e27b1d78320c9a60f50a30f43653138d 542 SUPERFAMILY SSF52540 215 448 3.05E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09545 e27b1d78320c9a60f50a30f43653138d 542 SUPERFAMILY SSF52540 490 527 3.05E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09545 e27b1d78320c9a60f50a30f43653138d 542 Pfam PF01078 Magnesium chelatase, subunit ChlI 216 423 8.5E-86 T 06-07-2017 IPR000523 Magnesium chelatase ChlI domain SMD11_RS09545 e27b1d78320c9a60f50a30f43653138d 542 Gene3D G3DSA:3.40.50.300 214 415 1.6E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09545 e27b1d78320c9a60f50a30f43653138d 542 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 432 527 1.7E-21 T 06-07-2017 IPR025158 Mg chelatase-related protein, C-terminal domain SMD11_RS09545 e27b1d78320c9a60f50a30f43653138d 542 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 141 1.5E-38 T 06-07-2017 SMD11_RS09545 e27b1d78320c9a60f50a30f43653138d 542 Gene3D G3DSA:3.30.230.10 7 169 1.0E-38 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS09545 e27b1d78320c9a60f50a30f43653138d 542 SMART SM00382 236 420 1.4E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS27525 c974fb3e3e4686e9f2f6ee4a5d43e2c4 282 Gene3D G3DSA:3.40.190.10 109 173 6.6E-24 T 06-07-2017 SMD11_RS27525 c974fb3e3e4686e9f2f6ee4a5d43e2c4 282 Gene3D G3DSA:3.40.190.10 1 108 1.2E-32 T 06-07-2017 SMD11_RS27525 c974fb3e3e4686e9f2f6ee4a5d43e2c4 282 Gene3D G3DSA:3.30.70.120 210 281 1.6E-26 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SMD11_RS27525 c974fb3e3e4686e9f2f6ee4a5d43e2c4 282 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 191 281 1.8E-28 T 06-07-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SMD11_RS27525 c974fb3e3e4686e9f2f6ee4a5d43e2c4 282 SUPERFAMILY SSF53850 1 208 4.73E-60 T 06-07-2017 SMD11_RS27525 c974fb3e3e4686e9f2f6ee4a5d43e2c4 282 Pfam PF01634 ATP phosphoribosyltransferase 49 203 5.8E-41 T 06-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SMD11_RS27525 c974fb3e3e4686e9f2f6ee4a5d43e2c4 282 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 282 31.501 T 06-07-2017 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 SMD11_RS27525 c974fb3e3e4686e9f2f6ee4a5d43e2c4 282 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 06-07-2017 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 SMD11_RS27525 c974fb3e3e4686e9f2f6ee4a5d43e2c4 282 Pfam PF08029 HisG, C-terminal domain 207 278 1.8E-24 T 06-07-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SMD11_RS27525 c974fb3e3e4686e9f2f6ee4a5d43e2c4 282 SUPERFAMILY SSF54913 210 281 3.11E-20 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta SMD11_RS27525 c974fb3e3e4686e9f2f6ee4a5d43e2c4 282 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 2.9E-51 T 06-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 SMD11_RS24420 4fbb52e6b456782056bde5e08274f07e 305 Gene3D G3DSA:3.20.20.220 11 303 6.4E-105 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like SMD11_RS24420 4fbb52e6b456782056bde5e08274f07e 305 SUPERFAMILY SSF51730 15 302 8.83E-94 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like SMD11_RS24420 4fbb52e6b456782056bde5e08274f07e 305 Pfam PF02219 Methylenetetrahydrofolate reductase 16 300 3.0E-109 T 06-07-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 SMD11_RS24420 4fbb52e6b456782056bde5e08274f07e 305 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 27 299 2.4E-98 T 06-07-2017 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 SMD11_RS14790 1d9bf3bca11fcdbde0ce8d627729cedb 243 Pfam PF01551 Peptidase family M23 130 231 4.2E-29 T 06-07-2017 IPR016047 Peptidase M23 SMD11_RS14790 1d9bf3bca11fcdbde0ce8d627729cedb 243 SUPERFAMILY SSF51261 91 236 2.3E-41 T 06-07-2017 IPR011055 Duplicated hybrid motif SMD11_RS14790 1d9bf3bca11fcdbde0ce8d627729cedb 243 Gene3D G3DSA:2.70.70.10 81 237 2.2E-42 T 06-07-2017 SMD11_RS21820 1486370e843b969997b0e0bc11d06552 300 Gene3D G3DSA:3.20.20.150 16 280 1.2E-65 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS21820 1486370e843b969997b0e0bc11d06552 300 SUPERFAMILY SSF51658 6 280 1.7E-57 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS21820 1486370e843b969997b0e0bc11d06552 300 Pfam PF01261 Xylose isomerase-like TIM barrel 32 227 1.6E-27 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 SUPERFAMILY SSF64484 22 1132 0.0 T 06-07-2017 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 23 1124 12.326 T 06-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Gene3D G3DSA:2.40.50.150 734 864 4.3E-56 T 06-07-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Gene3D G3DSA:2.40.50.100 627 697 6.1E-26 T 06-07-2017 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Pfam PF04563 RNA polymerase beta subunit 66 409 1.1E-20 T 06-07-2017 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 492 3.9E-29 T 06-07-2017 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Gene3D G3DSA:2.30.150.10 503 568 3.4E-26 T 06-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 ProSitePatterns PS01166 RNA polymerases beta chain signature. 868 880 - T 06-07-2017 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Gene3D G3DSA:3.90.1110.10 171 340 2.4E-68 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Pfam PF10385 RNA polymerase beta subunit external 1 domain 502 568 2.5E-24 T 06-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Gene3D G3DSA:2.40.270.10 698 725 4.9E-76 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Gene3D G3DSA:2.40.270.10 865 1024 4.9E-76 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Gene3D G3DSA:3.90.1100.10 29 169 1.9E-145 T 06-07-2017 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Gene3D G3DSA:3.90.1100.10 354 502 1.9E-145 T 06-07-2017 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Gene3D G3DSA:3.90.1100.10 571 625 1.9E-145 T 06-07-2017 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Pfam PF00562 RNA polymerase Rpb2, domain 6 630 1046 8.2E-156 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Pfam PF04560 RNA polymerase Rpb2, domain 7 1048 1122 4.0E-27 T 06-07-2017 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 Pfam PF04561 RNA polymerase Rpb2, domain 2 169 365 1.2E-28 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18845 1a787b4996faf47d305ed6b64f91d7c7 1160 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 237 842 0.0 T 06-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS03685 4b70642cb2bc76799a5f56f62f1c92f2 472 Pfam PF00027 Cyclic nucleotide-binding domain 118 206 3.7E-15 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain SMD11_RS03685 4b70642cb2bc76799a5f56f62f1c92f2 472 SUPERFAMILY SSF56563 306 407 1.57E-5 T 06-07-2017 SMD11_RS03685 4b70642cb2bc76799a5f56f62f1c92f2 472 Gene3D G3DSA:2.60.120.10 93 217 5.1E-24 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS03685 4b70642cb2bc76799a5f56f62f1c92f2 472 SUPERFAMILY SSF51206 90 214 7.07E-22 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like SMD11_RS03685 4b70642cb2bc76799a5f56f62f1c92f2 472 SMART SM00100 98 222 8.1E-12 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain SMD11_RS03685 4b70642cb2bc76799a5f56f62f1c92f2 472 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 126 142 - T 06-07-2017 IPR018488 Cyclic nucleotide-binding, conserved site SMD11_RS01170 76af0518216f7140e86e9f777823a079 56 SUPERFAMILY SSF57829 1 38 2.08E-9 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 SMD11_RS01170 76af0518216f7140e86e9f777823a079 56 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 38 6.8E-12 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS01170 76af0518216f7140e86e9f777823a079 56 Pfam PF01783 Ribosomal L32p protein family 2 43 6.9E-13 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS01170 76af0518216f7140e86e9f777823a079 56 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 52 13.519 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS04590 80a0cfe083827f227bd23e3c732fce29 316 Gene3D G3DSA:3.40.50.300 12 231 2.7E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04590 80a0cfe083827f227bd23e3c732fce29 316 Pfam PF00005 ABC transporter 31 167 9.6E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS04590 80a0cfe083827f227bd23e3c732fce29 316 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS04590 80a0cfe083827f227bd23e3c732fce29 316 SUPERFAMILY SSF52540 14 230 1.11E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04590 80a0cfe083827f227bd23e3c732fce29 316 SMART SM00382 39 224 7.1E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS26830 c81cfd45a6a3712b9fcd0716feed98c3 446 Pfam PF00324 Amino acid permease 1 436 3.1E-100 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMD11_RS26830 c81cfd45a6a3712b9fcd0716feed98c3 446 PIRSF PIRSF006060 1 443 7.6E-58 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS26830 c81cfd45a6a3712b9fcd0716feed98c3 446 ProSitePatterns PS00218 Amino acid permeases signature. 23 53 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD11_RS15935 c878336b80f427344537875a1fd1584f 447 SUPERFAMILY SSF103473 10 435 3.27E-40 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS15935 c878336b80f427344537875a1fd1584f 447 Pfam PF07690 Major Facilitator Superfamily 43 389 2.3E-21 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS15935 c878336b80f427344537875a1fd1584f 447 Gene3D G3DSA:1.20.1250.20 232 430 2.3E-14 T 06-07-2017 SMD11_RS15935 c878336b80f427344537875a1fd1584f 447 Gene3D G3DSA:1.20.1250.20 41 210 1.4E-12 T 06-07-2017 SMD11_RS06980 43cd010e76314d8caa10b7054d5eb349 299 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 8 168 1.0E-45 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD11_RS06980 43cd010e76314d8caa10b7054d5eb349 299 PIRSF PIRSF000103 1 299 2.5E-71 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD11_RS06980 43cd010e76314d8caa10b7054d5eb349 299 SUPERFAMILY SSF51735 6 168 7.1E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06980 43cd010e76314d8caa10b7054d5eb349 299 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 7 296 1.1E-118 T 06-07-2017 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 SMD11_RS06980 43cd010e76314d8caa10b7054d5eb349 299 SUPERFAMILY SSF48179 169 290 1.25E-33 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS06980 43cd010e76314d8caa10b7054d5eb349 299 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 171 289 3.4E-36 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 SMD11_RS06980 43cd010e76314d8caa10b7054d5eb349 299 Gene3D G3DSA:1.10.1040.10 170 296 1.6E-37 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS06980 43cd010e76314d8caa10b7054d5eb349 299 Gene3D G3DSA:3.40.50.720 6 169 1.4E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS22255 5c01be5c97d2df51ac03430591684a11 162 PIRSF PIRSF005384 1 149 2.1E-51 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMD11_RS22255 5c01be5c97d2df51ac03430591684a11 162 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 148 1.0E-72 T 06-07-2017 IPR011860 Ribose 5-phosphate isomerase GO:0004751 SMD11_RS22255 5c01be5c97d2df51ac03430591684a11 162 SUPERFAMILY SSF89623 1 152 3.14E-53 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMD11_RS22255 5c01be5c97d2df51ac03430591684a11 162 Gene3D G3DSA:3.40.1400.10 1 150 1.6E-55 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMD11_RS22255 5c01be5c97d2df51ac03430591684a11 162 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 1.1E-54 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMD11_RS22255 5c01be5c97d2df51ac03430591684a11 162 Pfam PF02502 Ribose/Galactose Isomerase 3 142 6.3E-47 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMD11_RS10435 b2de24807899198d42385272bd559590 559 SUPERFAMILY SSF55874 394 545 5.76E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS10435 b2de24807899198d42385272bd559590 559 Gene3D G3DSA:3.30.450.20 38 173 1.2E-40 T 06-07-2017 SMD11_RS10435 b2de24807899198d42385272bd559590 559 Gene3D G3DSA:1.10.287.130 310 372 1.4E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS10435 b2de24807899198d42385272bd559590 559 SUPERFAMILY SSF103190 41 170 9.81E-31 T 06-07-2017 IPR029151 Periplasmic sensor domain-like SMD11_RS10435 b2de24807899198d42385272bd559590 559 SMART SM00387 420 547 8.6E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS10435 b2de24807899198d42385272bd559590 559 Gene3D G3DSA:3.30.450.20 212 309 3.1E-9 T 06-07-2017 SMD11_RS10435 b2de24807899198d42385272bd559590 559 SUPERFAMILY SSF55785 209 311 3.14E-6 T 06-07-2017 IPR000014 PAS domain SMD11_RS10435 b2de24807899198d42385272bd559590 559 Pfam PF17203 Single cache domain 3 42 171 9.4E-30 T 06-07-2017 IPR033463 Single cache domain 3 SMD11_RS10435 b2de24807899198d42385272bd559590 559 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 546 2.3E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS10435 b2de24807899198d42385272bd559590 559 SUPERFAMILY SSF55890 323 390 1.14E-5 T 06-07-2017 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 SMD11_RS10435 b2de24807899198d42385272bd559590 559 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 487 1.3E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS10435 b2de24807899198d42385272bd559590 559 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 525 1.3E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS10435 b2de24807899198d42385272bd559590 559 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 544 1.3E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS10435 b2de24807899198d42385272bd559590 559 Gene3D G3DSA:3.30.565.10 384 545 5.1E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS29775 91e62411179708df5971ecf09f71f544 322 Gene3D G3DSA:3.40.50.980 34 199 8.0E-27 T 06-07-2017 SMD11_RS29775 91e62411179708df5971ecf09f71f544 322 Gene3D G3DSA:3.40.50.980 200 315 2.5E-12 T 06-07-2017 SMD11_RS29775 91e62411179708df5971ecf09f71f544 322 SUPERFAMILY SSF56801 33 312 2.62E-40 T 06-07-2017 SMD11_RS29775 91e62411179708df5971ecf09f71f544 322 Pfam PF00501 AMP-binding enzyme 41 311 6.5E-26 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS24635 e185b965ef9d73423a684556597a6357 1183 Gene3D G3DSA:2.40.50.140 1019 1099 8.5E-4 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS24635 e185b965ef9d73423a684556597a6357 1183 Pfam PF14579 Helix-hairpin-helix motif 832 920 5.8E-25 T 06-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS24635 e185b965ef9d73423a684556597a6357 1183 Pfam PF02811 PHP domain 11 197 4.9E-44 T 06-07-2017 IPR004013 PHP domain GO:0003824 SMD11_RS24635 e185b965ef9d73423a684556597a6357 1183 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 9 1061 0.0 T 06-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS24635 e185b965ef9d73423a684556597a6357 1183 SUPERFAMILY SSF89550 10 271 1.31E-29 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMD11_RS24635 e185b965ef9d73423a684556597a6357 1183 SMART SM00481 10 77 5.6E-28 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 SMD11_RS24635 e185b965ef9d73423a684556597a6357 1183 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 319 758 6.9E-164 T 06-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS24635 e185b965ef9d73423a684556597a6357 1183 Gene3D G3DSA:3.20.20.140 10 271 1.9E-38 T 06-07-2017 SMD11_RS05035 0af92e9626ad3331fc95b18daf1705bf 448 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 150 243 4.8E-7 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SMD11_RS05035 0af92e9626ad3331fc95b18daf1705bf 448 SUPERFAMILY SSF54675 4 131 1.02E-30 T 06-07-2017 SMD11_RS05035 0af92e9626ad3331fc95b18daf1705bf 448 PIRSF PIRSF000484 1 441 1.5E-112 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SMD11_RS05035 0af92e9626ad3331fc95b18daf1705bf 448 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 6 426 4.5E-126 T 06-07-2017 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SMD11_RS05035 0af92e9626ad3331fc95b18daf1705bf 448 SUPERFAMILY SSF51690 133 438 1.77E-86 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SMD11_RS05035 0af92e9626ad3331fc95b18daf1705bf 448 Gene3D G3DSA:3.20.140.10 4 354 1.0E-81 T 06-07-2017 SMD11_RS09235 735c2fd2fbed4bc451dc334a3336a6ce 98 SUPERFAMILY SSF103007 1 94 3.4E-31 T 06-07-2017 IPR007546 Protein of unknown function DUF503 SMD11_RS09235 735c2fd2fbed4bc451dc334a3336a6ce 98 Pfam PF04456 Protein of unknown function (DUF503) 3 89 2.7E-32 T 06-07-2017 IPR007546 Protein of unknown function DUF503 SMD11_RS09235 735c2fd2fbed4bc451dc334a3336a6ce 98 Gene3D G3DSA:3.30.70.1120 1 97 6.1E-37 T 06-07-2017 IPR007546 Protein of unknown function DUF503 SMD11_RS32885 2c771e7ae025a9b8da24b197fdc5ac78 601 SUPERFAMILY SSF47336 523 597 3.8E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32885 2c771e7ae025a9b8da24b197fdc5ac78 601 ProSitePatterns PS00012 Phosphopantetheine attachment site. 555 570 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32885 2c771e7ae025a9b8da24b197fdc5ac78 601 Gene3D G3DSA:3.30.300.30 416 534 2.0E-36 T 06-07-2017 SMD11_RS32885 2c771e7ae025a9b8da24b197fdc5ac78 601 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 45 445 1.5E-130 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS32885 2c771e7ae025a9b8da24b197fdc5ac78 601 SUPERFAMILY SSF56801 16 543 6.93E-153 T 06-07-2017 SMD11_RS32885 2c771e7ae025a9b8da24b197fdc5ac78 601 Gene3D G3DSA:3.40.50.980 175 333 2.0E-36 T 06-07-2017 SMD11_RS32885 2c771e7ae025a9b8da24b197fdc5ac78 601 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS32885 2c771e7ae025a9b8da24b197fdc5ac78 601 Pfam PF00501 AMP-binding enzyme 23 421 1.5E-100 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS32885 2c771e7ae025a9b8da24b197fdc5ac78 601 Pfam PF00550 Phosphopantetheine attachment site 534 595 1.2E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32885 2c771e7ae025a9b8da24b197fdc5ac78 601 Gene3D G3DSA:1.10.1200.10 535 599 2.0E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32885 2c771e7ae025a9b8da24b197fdc5ac78 601 Pfam PF13193 AMP-binding enzyme C-terminal domain 429 502 9.1E-13 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS32885 2c771e7ae025a9b8da24b197fdc5ac78 601 Gene3D G3DSA:3.40.50.980 17 174 1.9E-48 T 06-07-2017 SMD11_RS32885 2c771e7ae025a9b8da24b197fdc5ac78 601 SMART SM00823 Phosphopantetheine attachment site 528 600 8.3E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32885 2c771e7ae025a9b8da24b197fdc5ac78 601 Gene3D G3DSA:2.30.38.10 334 411 1.2E-26 T 06-07-2017 SMD11_RS06925 1378895d718959264eedf99c31a08372 539 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 23 537 4.6E-252 T 06-07-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMD11_RS06925 1378895d718959264eedf99c31a08372 539 Gene3D G3DSA:3.20.20.360 72 414 2.3E-116 T 06-07-2017 SMD11_RS06925 1378895d718959264eedf99c31a08372 539 Pfam PF01274 Malate synthase 17 536 5.8E-200 T 06-07-2017 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMD11_RS06925 1378895d718959264eedf99c31a08372 539 PIRSF PIRSF001363 5 539 6.6E-239 T 06-07-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMD11_RS06925 1378895d718959264eedf99c31a08372 539 ProSitePatterns PS00510 Malate synthase signature. 268 283 - T 06-07-2017 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMD11_RS06925 1378895d718959264eedf99c31a08372 539 SUPERFAMILY SSF51645 19 537 2.62E-177 T 06-07-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMD11_RS06925 1378895d718959264eedf99c31a08372 539 Gene3D G3DSA:1.20.1220.12 418 531 5.5E-27 T 06-07-2017 SMD11_RS28825 ce3d82636d8b7b4e426e53ed6de9c27a 230 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 30 221 8.5E-85 T 06-07-2017 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 SMD11_RS28825 ce3d82636d8b7b4e426e53ed6de9c27a 230 PIRSF PIRSF005624 11 229 2.2E-46 T 06-07-2017 SMD11_RS28825 ce3d82636d8b7b4e426e53ed6de9c27a 230 SUPERFAMILY SSF52540 24 226 5.28E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28825 ce3d82636d8b7b4e426e53ed6de9c27a 230 Gene3D G3DSA:3.40.50.300 28 219 7.3E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28825 ce3d82636d8b7b4e426e53ed6de9c27a 230 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 32 201 1.2E-34 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain SMD11_RS28825 ce3d82636d8b7b4e426e53ed6de9c27a 230 Hamap MF_01389 Urease accessory protein UreG [ureG]. 28 224 43.775 T 06-07-2017 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 SMD11_RS07545 e641650dd9e7d0158b941b5f02972f70 401 SUPERFAMILY SSF46785 14 72 1.36E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07545 e641650dd9e7d0158b941b5f02972f70 401 SUPERFAMILY SSF53067 81 385 7.69E-61 T 06-07-2017 SMD11_RS07545 e641650dd9e7d0158b941b5f02972f70 401 Gene3D G3DSA:3.30.420.40 222 363 1.4E-49 T 06-07-2017 SMD11_RS07545 e641650dd9e7d0158b941b5f02972f70 401 ProSitePatterns PS01125 ROK family signature. 217 244 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS07545 e641650dd9e7d0158b941b5f02972f70 401 Gene3D G3DSA:3.30.420.40 79 221 3.8E-45 T 06-07-2017 SMD11_RS07545 e641650dd9e7d0158b941b5f02972f70 401 Pfam PF12802 MarR family 19 70 2.1E-8 T 06-07-2017 SMD11_RS07545 e641650dd9e7d0158b941b5f02972f70 401 Gene3D G3DSA:1.10.10.10 12 76 1.6E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07545 e641650dd9e7d0158b941b5f02972f70 401 Pfam PF00480 ROK family 84 380 1.9E-59 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS19215 f9479aea3929931c1cd85dfe5b6ba58a 305 Pfam PF01522 Polysaccharide deacetylase 111 238 1.9E-19 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS19215 f9479aea3929931c1cd85dfe5b6ba58a 305 SUPERFAMILY SSF88713 101 304 6.67E-30 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS19215 f9479aea3929931c1cd85dfe5b6ba58a 305 Gene3D G3DSA:3.20.20.370 101 304 3.3E-28 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 468 2.2E-7 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 408 1.3E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 SMART SM00823 Phosphopantetheine attachment site 1570 1642 2.9E-28 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 SUPERFAMILY SSF53474 1689 1927 3.03E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 SUPERFAMILY SSF53474 1600 1638 3.03E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 SMART SM00824 Thioesterase 1714 1926 3.9E-108 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 284 1.3E-88 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 658 958 9.5E-117 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Gene3D G3DSA:3.40.47.10 297 461 1.2E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Gene3D G3DSA:3.40.47.10 471 511 1.9E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Gene3D G3DSA:3.40.47.10 521 560 7.6E-7 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Gene3D G3DSA:3.40.47.10 37 296 1.4E-90 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Gene3D G3DSA:3.40.50.720 1293 1475 1.1E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Pfam PF08659 KR domain 1292 1470 6.5E-56 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Gene3D G3DSA:3.40.366.10 849 961 2.1E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Gene3D G3DSA:3.40.366.10 647 780 2.1E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Pfam PF00975 Thioesterase domain 1721 1925 2.4E-21 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1597 1612 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 SMART SM01294 1571 1638 7.4E-5 T 06-07-2017 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 SUPERFAMILY SSF53901 32 405 1.73E-99 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Pfam PF00550 Phosphopantetheine attachment site 1572 1638 7.6E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 SUPERFAMILY SSF52151 850 946 5.23E-70 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 SUPERFAMILY SSF52151 655 786 5.23E-70 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 SUPERFAMILY SSF51735 1288 1522 8.21E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Gene3D G3DSA:3.40.50.1820 1657 1927 2.3E-78 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Gene3D G3DSA:1.10.1200.10 1570 1641 4.1E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Pfam PF00698 Acyl transferase domain 657 977 5.4E-58 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 SMART SM00825 Beta-ketoacyl synthase 37 462 1.3E-213 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1292 1472 3.3E-52 T 06-07-2017 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 Gene3D G3DSA:3.30.70.250 784 848 5.1E-7 T 06-07-2017 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 SUPERFAMILY SSF55048 784 849 2.62E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08035 f899af15ffae422802cf7228de3f1fbf 1944 SUPERFAMILY SSF51735 1072 1282 1.3E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS27445 5209ceab0a5653b8f935de4340b50c0f 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMD11_RS27445 5209ceab0a5653b8f935de4340b50c0f 151 Gene3D G3DSA:1.10.10.10 5 55 5.5E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27445 5209ceab0a5653b8f935de4340b50c0f 151 Pfam PF01037 Lrp/AsnC ligand binding domain 69 139 1.2E-14 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS27445 5209ceab0a5653b8f935de4340b50c0f 151 Gene3D G3DSA:3.30.70.920 56 135 1.6E-19 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS27445 5209ceab0a5653b8f935de4340b50c0f 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.0E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS27445 5209ceab0a5653b8f935de4340b50c0f 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.0E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS27445 5209ceab0a5653b8f935de4340b50c0f 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.0E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS27445 5209ceab0a5653b8f935de4340b50c0f 151 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 5.5E-16 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS27445 5209ceab0a5653b8f935de4340b50c0f 151 SUPERFAMILY SSF46785 2 63 1.59E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27445 5209ceab0a5653b8f935de4340b50c0f 151 SUPERFAMILY SSF54909 65 143 2.41E-13 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS27445 5209ceab0a5653b8f935de4340b50c0f 151 SMART SM00344 3 110 1.9E-30 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD11_RS21610 b130a4eec26298669e8bd80444621db4 220 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 22 173 4.0E-5 T 06-07-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 SMD11_RS21610 b130a4eec26298669e8bd80444621db4 220 SUPERFAMILY SSF52540 17 197 1.03E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21610 b130a4eec26298669e8bd80444621db4 220 Gene3D G3DSA:3.40.50.300 14 209 1.1E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30705 fb2eb5e9fb4fd6b350588fc4f89732f7 286 Pfam PF00005 ABC transporter 34 182 3.8E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS30705 fb2eb5e9fb4fd6b350588fc4f89732f7 286 SUPERFAMILY SSF52540 18 247 8.42E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30705 fb2eb5e9fb4fd6b350588fc4f89732f7 286 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS30705 fb2eb5e9fb4fd6b350588fc4f89732f7 286 SMART SM00382 42 232 1.4E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS30705 fb2eb5e9fb4fd6b350588fc4f89732f7 286 Gene3D G3DSA:3.40.50.300 20 258 1.7E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS33200 76a660bbf35506d0f5c858f602e68a88 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 62 73 5.6E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33200 76a660bbf35506d0f5c858f602e68a88 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 5.6E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33200 76a660bbf35506d0f5c858f602e68a88 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 5.6E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33200 76a660bbf35506d0f5c858f602e68a88 237 Pfam PF00106 short chain dehydrogenase 4 186 2.2E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33200 76a660bbf35506d0f5c858f602e68a88 237 Gene3D G3DSA:3.40.50.720 1 215 5.2E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33200 76a660bbf35506d0f5c858f602e68a88 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 62 73 4.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33200 76a660bbf35506d0f5c858f602e68a88 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33200 76a660bbf35506d0f5c858f602e68a88 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 4.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33200 76a660bbf35506d0f5c858f602e68a88 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 4.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33200 76a660bbf35506d0f5c858f602e68a88 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 4.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33200 76a660bbf35506d0f5c858f602e68a88 237 SUPERFAMILY SSF51735 3 211 1.02E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32225 c32ffa74bd7d0f9ba802010cb2e32ab5 158 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 3 116 5.4E-48 T 06-07-2017 IPR028973 PhnB-like SMD11_RS32225 c32ffa74bd7d0f9ba802010cb2e32ab5 158 Gene3D G3DSA:3.10.180.10 1 129 3.5E-48 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS32225 c32ffa74bd7d0f9ba802010cb2e32ab5 158 PIRSF PIRSF021700 1 157 5.4E-62 T 06-07-2017 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase SMD11_RS32225 c32ffa74bd7d0f9ba802010cb2e32ab5 158 SUPERFAMILY SSF54593 3 155 3.53E-47 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS22120 801a80a39e177d8fe768dc92b74c9e22 398 SUPERFAMILY SSF53067 73 372 3.94E-37 T 06-07-2017 SMD11_RS22120 801a80a39e177d8fe768dc92b74c9e22 398 Gene3D G3DSA:3.30.420.40 211 351 5.8E-30 T 06-07-2017 SMD11_RS22120 801a80a39e177d8fe768dc92b74c9e22 398 Pfam PF12802 MarR family 4 49 7.4E-8 T 06-07-2017 SMD11_RS22120 801a80a39e177d8fe768dc92b74c9e22 398 Pfam PF00480 ROK family 81 340 2.5E-30 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS22120 801a80a39e177d8fe768dc92b74c9e22 398 SUPERFAMILY SSF46785 1 64 1.87E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS22120 801a80a39e177d8fe768dc92b74c9e22 398 Gene3D G3DSA:3.30.420.40 66 210 4.7E-35 T 06-07-2017 SMD11_RS22120 801a80a39e177d8fe768dc92b74c9e22 398 Gene3D G3DSA:1.10.10.10 6 64 1.4E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15970 a5c86d0219e387fd0d962b65b3b87411 631 Gene3D G3DSA:3.60.120.10 116 394 8.5E-60 T 06-07-2017 IPR005801 ADC synthase GO:0009058 SMD11_RS15970 a5c86d0219e387fd0d962b65b3b87411 631 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 479 493 7.2E-5 T 06-07-2017 SMD11_RS15970 a5c86d0219e387fd0d962b65b3b87411 631 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 515 531 7.2E-5 T 06-07-2017 SMD11_RS15970 a5c86d0219e387fd0d962b65b3b87411 631 Gene3D G3DSA:3.40.50.880 440 620 2.4E-27 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS15970 a5c86d0219e387fd0d962b65b3b87411 631 SUPERFAMILY SSF56322 102 393 5.63E-64 T 06-07-2017 IPR005801 ADC synthase GO:0009058 SMD11_RS15970 a5c86d0219e387fd0d962b65b3b87411 631 PRINTS PR00097 Anthranilate synthase component II signature 515 526 1.2E-6 T 06-07-2017 SMD11_RS15970 a5c86d0219e387fd0d962b65b3b87411 631 PRINTS PR00097 Anthranilate synthase component II signature 600 613 1.2E-6 T 06-07-2017 SMD11_RS15970 a5c86d0219e387fd0d962b65b3b87411 631 PRINTS PR00097 Anthranilate synthase component II signature 441 455 1.2E-6 T 06-07-2017 SMD11_RS15970 a5c86d0219e387fd0d962b65b3b87411 631 Pfam PF00117 Glutamine amidotransferase class-I 443 616 7.7E-21 T 06-07-2017 IPR017926 Glutamine amidotransferase SMD11_RS15970 a5c86d0219e387fd0d962b65b3b87411 631 SUPERFAMILY SSF52317 438 619 9.72E-23 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS15970 a5c86d0219e387fd0d962b65b3b87411 631 PRINTS PR00096 Glutamine amidotransferase superfamily signature 482 491 3.2E-8 T 06-07-2017 SMD11_RS15970 a5c86d0219e387fd0d962b65b3b87411 631 PRINTS PR00096 Glutamine amidotransferase superfamily signature 600 613 3.2E-8 T 06-07-2017 SMD11_RS15970 a5c86d0219e387fd0d962b65b3b87411 631 PRINTS PR00096 Glutamine amidotransferase superfamily signature 515 526 3.2E-8 T 06-07-2017 SMD11_RS15970 a5c86d0219e387fd0d962b65b3b87411 631 Pfam PF00425 chorismate binding enzyme 126 385 1.8E-46 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal SMD11_RS28695 e613c96005ade66f6addcd60337af922 244 Gene3D G3DSA:3.40.1410.10 106 233 4.6E-21 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS28695 e613c96005ade66f6addcd60337af922 244 SUPERFAMILY SSF64288 63 234 1.52E-25 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS28695 e613c96005ade66f6addcd60337af922 244 Gene3D G3DSA:1.10.10.10 10 79 4.9E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28695 e613c96005ade66f6addcd60337af922 244 SMART SM00345 17 75 7.2E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS28695 e613c96005ade66f6addcd60337af922 244 SMART SM00866 89 231 6.1E-8 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS28695 e613c96005ade66f6addcd60337af922 244 SUPERFAMILY SSF46785 12 79 2.3E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28695 e613c96005ade66f6addcd60337af922 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 2.0E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS28695 e613c96005ade66f6addcd60337af922 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 2.0E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS28695 e613c96005ade66f6addcd60337af922 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 75 4.4E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS28695 e613c96005ade66f6addcd60337af922 244 Pfam PF07702 UTRA domain 106 229 1.8E-13 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS20135 c752e74c4b53bfcd658ada112a01aa0e 165 SMART SM00347 43 146 2.3E-22 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS20135 c752e74c4b53bfcd658ada112a01aa0e 165 SUPERFAMILY SSF46785 11 160 5.65E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20135 c752e74c4b53bfcd658ada112a01aa0e 165 Pfam PF01047 MarR family 54 111 7.3E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS20135 c752e74c4b53bfcd658ada112a01aa0e 165 ProSitePatterns PS01117 MarR-type HTH domain signature. 85 119 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site SMD11_RS20135 c752e74c4b53bfcd658ada112a01aa0e 165 Gene3D G3DSA:1.10.10.10 9 161 1.3E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20135 c752e74c4b53bfcd658ada112a01aa0e 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 3.5E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS20135 c752e74c4b53bfcd658ada112a01aa0e 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 3.5E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS20135 c752e74c4b53bfcd658ada112a01aa0e 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 3.5E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS20135 c752e74c4b53bfcd658ada112a01aa0e 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 3.5E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS26650 e5dbd1ed836cea8f00255287b6e6f1d8 242 SUPERFAMILY SSF46785 22 90 4.73E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26650 e5dbd1ed836cea8f00255287b6e6f1d8 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 86 1.4E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS26650 e5dbd1ed836cea8f00255287b6e6f1d8 242 Gene3D G3DSA:1.20.120.530 108 240 1.1E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS26650 e5dbd1ed836cea8f00255287b6e6f1d8 242 SMART SM00345 25 86 3.8E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS26650 e5dbd1ed836cea8f00255287b6e6f1d8 242 Gene3D G3DSA:1.10.10.10 26 92 7.8E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26650 e5dbd1ed836cea8f00255287b6e6f1d8 242 Pfam PF07729 FCD domain 112 229 7.6E-19 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS26650 e5dbd1ed836cea8f00255287b6e6f1d8 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 6.2E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS26650 e5dbd1ed836cea8f00255287b6e6f1d8 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 6.2E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS26650 e5dbd1ed836cea8f00255287b6e6f1d8 242 SUPERFAMILY SSF48008 108 240 7.32E-23 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS26650 e5dbd1ed836cea8f00255287b6e6f1d8 242 SMART SM00895 111 232 3.4E-18 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS08770 b6a9a95184ad7b91579e655325384987 538 ProSitePatterns PS00211 ABC transporters family signature. 460 474 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS08770 b6a9a95184ad7b91579e655325384987 538 SUPERFAMILY SSF52540 364 533 3.0E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08770 b6a9a95184ad7b91579e655325384987 538 Pfam PF00005 ABC transporter 20 188 1.8E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS08770 b6a9a95184ad7b91579e655325384987 538 Pfam PF00005 ABC transporter 364 488 1.6E-19 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS08770 b6a9a95184ad7b91579e655325384987 538 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS08770 b6a9a95184ad7b91579e655325384987 538 SUPERFAMILY SSF52540 5 230 1.02E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08770 b6a9a95184ad7b91579e655325384987 538 SMART SM00382 29 233 3.4E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS08770 b6a9a95184ad7b91579e655325384987 538 SMART SM00382 369 533 2.9E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS08770 b6a9a95184ad7b91579e655325384987 538 Gene3D G3DSA:3.40.50.300 364 529 2.5E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08770 b6a9a95184ad7b91579e655325384987 538 Gene3D G3DSA:3.40.50.300 134 272 9.8E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08770 b6a9a95184ad7b91579e655325384987 538 Gene3D G3DSA:3.40.50.300 4 101 9.8E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02690 cc23a9c5b395243fca46efa28208df2f 582 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 105 481 2.6E-72 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain SMD11_RS02690 cc23a9c5b395243fca46efa28208df2f 582 SUPERFAMILY SSF53850 51 560 1.41E-93 T 06-07-2017 SMD11_RS02690 cc23a9c5b395243fca46efa28208df2f 582 Gene3D G3DSA:3.10.105.10 326 541 3.4E-37 T 06-07-2017 SMD11_RS02690 cc23a9c5b395243fca46efa28208df2f 582 Gene3D G3DSA:3.90.76.10 67 242 2.1E-38 T 06-07-2017 SMD11_RS02690 cc23a9c5b395243fca46efa28208df2f 582 PIRSF PIRSF002741 5 567 7.5E-62 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD11_RS00485 51732d6f98182696b47868f36080e9c3 394 Gene3D G3DSA:3.30.70.360 196 291 3.7E-16 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS00485 51732d6f98182696b47868f36080e9c3 394 Gene3D G3DSA:3.40.630.10 8 195 3.6E-36 T 06-07-2017 SMD11_RS00485 51732d6f98182696b47868f36080e9c3 394 Gene3D G3DSA:3.40.630.10 332 392 3.6E-36 T 06-07-2017 SMD11_RS00485 51732d6f98182696b47868f36080e9c3 394 SUPERFAMILY SSF55031 187 296 1.79E-12 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS00485 51732d6f98182696b47868f36080e9c3 394 Pfam PF01546 Peptidase family M20/M25/M40 83 388 1.4E-21 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD11_RS00485 51732d6f98182696b47868f36080e9c3 394 Pfam PF07687 Peptidase dimerisation domain 184 290 7.5E-15 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS00485 51732d6f98182696b47868f36080e9c3 394 SUPERFAMILY SSF53187 316 392 3.43E-31 T 06-07-2017 SMD11_RS00485 51732d6f98182696b47868f36080e9c3 394 SUPERFAMILY SSF53187 7 195 3.43E-31 T 06-07-2017 SMD11_RS01045 6042f4f118fdd191a637837d6bb90bb8 221 Gene3D G3DSA:3.40.50.2300 9 159 1.5E-39 T 06-07-2017 SMD11_RS01045 6042f4f118fdd191a637837d6bb90bb8 221 SMART SM00421 158 215 2.3E-25 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS01045 6042f4f118fdd191a637837d6bb90bb8 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 215 7.2E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS01045 6042f4f118fdd191a637837d6bb90bb8 221 SUPERFAMILY SSF52172 9 191 9.96E-34 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS01045 6042f4f118fdd191a637837d6bb90bb8 221 SMART SM00448 11 124 3.7E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS01045 6042f4f118fdd191a637837d6bb90bb8 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 1.1E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS01045 6042f4f118fdd191a637837d6bb90bb8 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 1.1E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS01045 6042f4f118fdd191a637837d6bb90bb8 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 1.1E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS01045 6042f4f118fdd191a637837d6bb90bb8 221 Pfam PF00072 Response regulator receiver domain 13 124 4.5E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS01045 6042f4f118fdd191a637837d6bb90bb8 221 Gene3D G3DSA:1.10.10.10 160 220 4.7E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01045 6042f4f118fdd191a637837d6bb90bb8 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS32910 15dfc661faaa178833f08f1f9ff4b08f 422 Pfam PF14399 Butirosin biosynthesis protein H, N-terminal 99 224 6.3E-25 T 06-07-2017 IPR026935 Butirosin biosynthesis protein H, N-terminal KEGG: 00524+2.3.2.19|MetaCyc: PWY-7019 SMD11_RS14985 458cc6b881c8772dd95068e7a1f61d7f 561 Pfam PF06738 Putative threonine/serine exporter 144 383 3.5E-60 T 06-07-2017 IPR010619 Putative threonine/serine exporter SMD11_RS14985 458cc6b881c8772dd95068e7a1f61d7f 561 Pfam PF12821 Threonine/Serine exporter, ThrE 409 534 2.5E-19 T 06-07-2017 IPR024528 Threonine/Serine exporter, ThrE SMD11_RS26880 b363bcea043cd78b0673fd1e85a98866 422 Pfam PF01546 Peptidase family M20/M25/M40 72 364 7.9E-24 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD11_RS26880 b363bcea043cd78b0673fd1e85a98866 422 SUPERFAMILY SSF53187 3 207 6.86E-75 T 06-07-2017 SMD11_RS26880 b363bcea043cd78b0673fd1e85a98866 422 SUPERFAMILY SSF53187 310 414 6.86E-75 T 06-07-2017 SMD11_RS26880 b363bcea043cd78b0673fd1e85a98866 422 Pfam PF07687 Peptidase dimerisation domain 198 289 2.3E-11 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS26880 b363bcea043cd78b0673fd1e85a98866 422 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 19 350 7.6E-75 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 SMD11_RS26880 b363bcea043cd78b0673fd1e85a98866 422 Gene3D G3DSA:3.30.70.360 192 309 4.6E-32 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS26880 b363bcea043cd78b0673fd1e85a98866 422 PIRSF PIRSF005962 3 416 9.4E-93 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 SMD11_RS26880 b363bcea043cd78b0673fd1e85a98866 422 SUPERFAMILY SSF55031 194 302 7.85E-25 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS26880 b363bcea043cd78b0673fd1e85a98866 422 Gene3D G3DSA:3.40.630.10 310 414 1.7E-86 T 06-07-2017 SMD11_RS26880 b363bcea043cd78b0673fd1e85a98866 422 Gene3D G3DSA:3.40.630.10 3 188 1.7E-86 T 06-07-2017 SMD11_RS32015 7dad8f8114d5dc3b298aaee9cbd81587 353 Gene3D G3DSA:3.30.470.30 32 148 5.9E-26 T 06-07-2017 SMD11_RS32015 7dad8f8114d5dc3b298aaee9cbd81587 353 SUPERFAMILY SSF56091 6 192 1.1E-40 T 06-07-2017 SMD11_RS32015 7dad8f8114d5dc3b298aaee9cbd81587 353 Gene3D G3DSA:2.40.50.140 200 335 2.1E-11 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS32015 7dad8f8114d5dc3b298aaee9cbd81587 353 Gene3D G3DSA:3.30.1490.70 156 197 3.3E-10 T 06-07-2017 SMD11_RS32015 7dad8f8114d5dc3b298aaee9cbd81587 353 Gene3D G3DSA:3.30.1490.70 3 31 3.3E-10 T 06-07-2017 SMD11_RS32015 7dad8f8114d5dc3b298aaee9cbd81587 353 Pfam PF04679 ATP dependent DNA ligase C terminal region 215 329 6.0E-16 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 SMD11_RS32015 7dad8f8114d5dc3b298aaee9cbd81587 353 SUPERFAMILY SSF50249 200 338 4.8E-12 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS32015 7dad8f8114d5dc3b298aaee9cbd81587 353 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 27 35 - T 06-07-2017 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 SMD11_RS32015 7dad8f8114d5dc3b298aaee9cbd81587 353 Pfam PF01068 ATP dependent DNA ligase domain 11 197 9.9E-35 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 SMD11_RS34640 92466822ad0d52c94a16a778c12100c1 258 SUPERFAMILY SSF46689 14 93 3.85E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS34640 92466822ad0d52c94a16a778c12100c1 258 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 5.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS34640 92466822ad0d52c94a16a778c12100c1 258 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 5.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS34640 92466822ad0d52c94a16a778c12100c1 258 SUPERFAMILY SSF48498 105 203 8.15E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS34640 92466822ad0d52c94a16a778c12100c1 258 Gene3D G3DSA:1.10.357.10 13 204 8.0E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS34640 92466822ad0d52c94a16a778c12100c1 258 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 2.4E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS25830 082d88a97046a0b7aecb2495e91c2a9a 270 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 75 237 2.1E-30 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SMD11_RS25830 082d88a97046a0b7aecb2495e91c2a9a 270 SUPERFAMILY SSF46785 152 225 3.3E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS25830 082d88a97046a0b7aecb2495e91c2a9a 270 Gene3D G3DSA:1.10.10.10 152 225 7.3E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS25830 082d88a97046a0b7aecb2495e91c2a9a 270 SUPERFAMILY SSF46785 74 147 4.04E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS25830 082d88a97046a0b7aecb2495e91c2a9a 270 Gene3D G3DSA:1.10.10.10 74 148 2.7E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS25830 082d88a97046a0b7aecb2495e91c2a9a 270 Pfam PF04079 Segregation and condensation complex subunit ScpB 77 234 2.4E-56 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SMD11_RS02395 5dcac3b972858fbeee60947acd10074c 233 Gene3D G3DSA:1.20.120.530 92 219 2.2E-29 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS02395 5dcac3b972858fbeee60947acd10074c 233 Gene3D G3DSA:1.10.10.10 14 78 8.9E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02395 5dcac3b972858fbeee60947acd10074c 233 SUPERFAMILY SSF48008 93 224 9.42E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS02395 5dcac3b972858fbeee60947acd10074c 233 SMART SM00345 16 75 1.2E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS02395 5dcac3b972858fbeee60947acd10074c 233 SUPERFAMILY SSF46785 10 88 2.57E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02395 5dcac3b972858fbeee60947acd10074c 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 7.0E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS02395 5dcac3b972858fbeee60947acd10074c 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 7.0E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS02395 5dcac3b972858fbeee60947acd10074c 233 SMART SM00895 96 220 1.7E-23 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS02395 5dcac3b972858fbeee60947acd10074c 233 Pfam PF07729 FCD domain 97 218 1.2E-24 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS02395 5dcac3b972858fbeee60947acd10074c 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 1.5E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS22475 aed6c25af048658867417e35c3e4b62b 439 Gene3D G3DSA:3.40.309.10 239 390 5.1E-42 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS22475 aed6c25af048658867417e35c3e4b62b 439 Pfam PF00171 Aldehyde dehydrogenase family 18 297 1.7E-21 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS22475 aed6c25af048658867417e35c3e4b62b 439 SUPERFAMILY SSF53720 18 432 4.32E-116 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS22475 aed6c25af048658867417e35c3e4b62b 439 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 17 432 42.534 T 06-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMD11_RS22475 aed6c25af048658867417e35c3e4b62b 439 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 339 360 - T 06-07-2017 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMD11_RS22475 aed6c25af048658867417e35c3e4b62b 439 PIRSF PIRSF000151 13 433 4.5E-175 T 06-07-2017 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 SMD11_RS22475 aed6c25af048658867417e35c3e4b62b 439 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 25 422 1.6E-155 T 06-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMD11_RS22475 aed6c25af048658867417e35c3e4b62b 439 Gene3D G3DSA:3.40.605.10 16 236 1.3E-103 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS22475 aed6c25af048658867417e35c3e4b62b 439 Gene3D G3DSA:3.40.605.10 391 432 1.3E-103 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS27415 2d30ad55945b6b8a35e72e6e9753979b 311 SUPERFAMILY SSF53328 1 206 1.06E-56 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS27415 2d30ad55945b6b8a35e72e6e9753979b 311 Pfam PF02911 Formyl transferase, C-terminal domain 204 300 1.0E-24 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS27415 2d30ad55945b6b8a35e72e6e9753979b 311 SUPERFAMILY SSF50486 205 308 1.16E-28 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 SMD11_RS27415 2d30ad55945b6b8a35e72e6e9753979b 311 Gene3D G3DSA:3.10.25.10 208 309 5.4E-32 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS27415 2d30ad55945b6b8a35e72e6e9753979b 311 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 303 32.863 T 06-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 SMD11_RS27415 2d30ad55945b6b8a35e72e6e9753979b 311 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 301 5.5E-68 T 06-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 SMD11_RS27415 2d30ad55945b6b8a35e72e6e9753979b 311 Gene3D G3DSA:3.40.50.170 1 205 7.9E-59 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS27415 2d30ad55945b6b8a35e72e6e9753979b 311 Pfam PF00551 Formyl transferase 2 177 1.4E-33 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 Pfam PF13424 Tetratricopeptide repeat 842 910 1.1E-12 T 06-07-2017 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 SUPERFAMILY SSF52540 312 571 3.36E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 Gene3D G3DSA:1.25.40.10 139 155 5.5E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 Gene3D G3DSA:1.25.40.10 726 820 5.5E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 Gene3D G3DSA:1.25.40.10 821 1034 1.2E-33 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 SUPERFAMILY SSF46894 39 130 2.83E-10 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 Pfam PF00931 NB-ARC domain 344 574 3.5E-10 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 SUPERFAMILY SSF48452 133 296 4.3E-26 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 SMART SM01043 137 281 2.1E-32 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 SUPERFAMILY SSF48452 869 1076 2.58E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 PRINTS PR00364 Disease resistance protein signature 505 519 2.4E-6 T 06-07-2017 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 PRINTS PR00364 Disease resistance protein signature 342 357 2.4E-6 T 06-07-2017 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 PRINTS PR00364 Disease resistance protein signature 421 435 2.4E-6 T 06-07-2017 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 Pfam PF03704 Bacterial transcriptional activator domain 137 281 4.7E-27 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 SMART SM00028 839 872 0.0016 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 SMART SM00028 759 792 450.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 SMART SM00028 999 1032 35.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 SMART SM00028 919 952 90.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 SMART SM00028 799 832 120.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 SMART SM00028 879 912 0.037 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 Gene3D G3DSA:1.25.40.10 156 258 1.9E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 SMART SM00862 52 130 2.6E-4 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS04270 05766b089a75823212816a8ba3b9e215 1090 SUPERFAMILY SSF48452 715 874 7.36E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS32825 2a164f02791a1b9ee405d7fc335db966 352 Gene3D G3DSA:3.40.50.40 209 313 7.3E-20 T 06-07-2017 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 SMD11_RS32825 2a164f02791a1b9ee405d7fc335db966 352 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 79 89 - T 06-07-2017 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 SMD11_RS32825 2a164f02791a1b9ee405d7fc335db966 352 Gene3D G3DSA:3.40.50.1170 3 196 2.2E-48 T 06-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 SMD11_RS32825 2a164f02791a1b9ee405d7fc335db966 352 SMART SM00870 3 321 1.6E-82 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 SMD11_RS32825 2a164f02791a1b9ee405d7fc335db966 352 SUPERFAMILY SSF53774 3 310 2.09E-76 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 SMD11_RS32825 2a164f02791a1b9ee405d7fc335db966 352 PIRSF PIRSF001220 1 325 6.8E-76 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 SMD11_RS32825 2a164f02791a1b9ee405d7fc335db966 352 Pfam PF00710 Asparaginase, N-terminal 3 190 3.8E-46 T 06-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 SMD11_RS32825 2a164f02791a1b9ee405d7fc335db966 352 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 06-07-2017 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 SMD11_RS32825 2a164f02791a1b9ee405d7fc335db966 352 PIRSF PIRSF500176 1 322 8.2E-79 T 06-07-2017 SMD11_RS32825 2a164f02791a1b9ee405d7fc335db966 352 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 1.8E-18 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 SMD11_RS32825 2a164f02791a1b9ee405d7fc335db966 352 PRINTS PR00139 Asparaginase/glutaminase family signature 78 96 1.8E-18 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 SMD11_RS32825 2a164f02791a1b9ee405d7fc335db966 352 PRINTS PR00139 Asparaginase/glutaminase family signature 256 274 1.8E-18 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 SMD11_RS14945 99fc1b1236c651dfe849f0d2618d25df 369 Gene3D G3DSA:3.40.50.1820 109 366 7.9E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS14945 99fc1b1236c651dfe849f0d2618d25df 369 SUPERFAMILY SSF53474 111 367 4.16E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS14945 99fc1b1236c651dfe849f0d2618d25df 369 Pfam PF00756 Putative esterase 131 357 9.1E-14 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 Pfam PF00122 E1-E2 ATPase 89 318 3.0E-37 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 SUPERFAMILY SSF81665 55 120 3.4E-10 T 06-07-2017 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 SUPERFAMILY SSF81665 230 321 3.4E-10 T 06-07-2017 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 Gene3D G3DSA:2.70.150.10 68 230 5.0E-22 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 SUPERFAMILY SSF81660 338 480 2.58E-26 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 329 335 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 Pfam PF00702 haloacid dehalogenase-like hydrolase 323 559 1.8E-31 T 06-07-2017 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 34 707 7.5E-292 T 06-07-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 SUPERFAMILY SSF56784 315 339 1.44E-37 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 SUPERFAMILY SSF56784 413 588 1.44E-37 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 176 190 7.0E-25 T 06-07-2017 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 568 580 7.0E-25 T 06-07-2017 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 545 564 7.0E-25 T 06-07-2017 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 327 341 7.0E-25 T 06-07-2017 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 492 502 7.0E-25 T 06-07-2017 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 90 348 4.3E-27 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 467 622 1.8E-36 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 32 711 39.119 T 06-07-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 Gene3D G3DSA:3.40.50.1000 474 592 2.7E-35 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 Gene3D G3DSA:3.40.1110.10 338 473 1.9E-41 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS21775 54b0019a6ba8c12864a8a98e6859e562 713 SUPERFAMILY SSF81653 135 229 3.27E-20 T 06-07-2017 SMD11_RS27885 46811e84f7ab5875599eb6b0f1d8124d 502 Gene3D G3DSA:3.40.640.10 137 351 1.1E-42 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS27885 46811e84f7ab5875599eb6b0f1d8124d 502 Gene3D G3DSA:1.10.10.10 34 98 2.5E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27885 46811e84f7ab5875599eb6b0f1d8124d 502 SUPERFAMILY SSF53383 122 482 1.35E-72 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS27885 46811e84f7ab5875599eb6b0f1d8124d 502 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 74 1.8E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS27885 46811e84f7ab5875599eb6b0f1d8124d 502 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 74 90 1.8E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS27885 46811e84f7ab5875599eb6b0f1d8124d 502 SUPERFAMILY SSF46785 34 102 7.67E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27885 46811e84f7ab5875599eb6b0f1d8124d 502 Pfam PF00392 Bacterial regulatory proteins, gntR family 38 97 6.4E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS27885 46811e84f7ab5875599eb6b0f1d8124d 502 Gene3D G3DSA:3.90.1150.10 352 482 1.9E-18 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS27885 46811e84f7ab5875599eb6b0f1d8124d 502 Pfam PF00155 Aminotransferase class I and II 162 479 6.8E-29 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS27885 46811e84f7ab5875599eb6b0f1d8124d 502 SMART SM00345 41 100 2.0E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 Pfam PF13246 Cation transport ATPase (P-type) 355 440 1.5E-23 T 06-07-2017 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 294 308 6.9E-37 T 06-07-2017 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 615 627 6.9E-37 T 06-07-2017 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 493 504 6.9E-37 T 06-07-2017 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 515 525 6.9E-37 T 06-07-2017 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 139 153 6.9E-37 T 06-07-2017 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 591 610 6.9E-37 T 06-07-2017 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 SUPERFAMILY SSF56784 452 694 6.86E-53 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 SUPERFAMILY SSF56784 292 312 6.86E-53 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 296 302 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 SUPERFAMILY SSF81665 1 92 3.66E-99 T 06-07-2017 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 SUPERFAMILY SSF81665 641 827 3.66E-99 T 06-07-2017 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 SUPERFAMILY SSF81665 195 288 3.66E-99 T 06-07-2017 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 455 473 1.6E-16 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 591 607 1.6E-16 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 563 579 1.6E-16 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 623 648 1.6E-16 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 SMART SM00831 1 54 4.1E-8 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 Pfam PF00690 Cation transporter/ATPase, N-terminus 1 48 1.9E-12 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 Pfam PF00122 E1-E2 ATPase 60 285 1.5E-61 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 61 313 2.9E-46 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 562 682 1.1E-29 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 Gene3D G3DSA:1.20.1110.10 34 86 7.9E-92 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 Gene3D G3DSA:1.20.1110.10 560 822 7.9E-92 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 SUPERFAMILY SSF81660 301 497 9.42E-49 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 Pfam PF00689 Cation transporting ATPase, C-terminus 676 824 3.0E-33 T 06-07-2017 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 SUPERFAMILY SSF81653 92 195 4.71E-27 T 06-07-2017 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 Gene3D G3DSA:2.70.150.10 3 33 3.2E-36 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 Gene3D G3DSA:2.70.150.10 87 195 3.2E-36 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS05020 adc01f88482636bec2041eb8fb1d2640 858 Gene3D G3DSA:3.40.1110.10 284 500 1.3E-49 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS18685 f95c9d7661967374f6bf7f510b7b8276 131 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 12 131 16.633 T 06-07-2017 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 SMD11_RS18685 f95c9d7661967374f6bf7f510b7b8276 131 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 31 130 1.6E-30 T 06-07-2017 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS20580 d91d92d50bef43b4088265d9e4ca7be8 389 SUPERFAMILY SSF56059 112 310 1.04E-58 T 06-07-2017 SMD11_RS20580 d91d92d50bef43b4088265d9e4ca7be8 389 Pfam PF02222 ATP-grasp domain 121 290 6.7E-49 T 06-07-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type SMD11_RS20580 d91d92d50bef43b4088265d9e4ca7be8 389 Gene3D G3DSA:3.40.50.20 14 118 1.0E-28 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS20580 d91d92d50bef43b4088265d9e4ca7be8 389 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 16 374 1.9E-116 T 06-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 SMD11_RS20580 d91d92d50bef43b4088265d9e4ca7be8 389 Gene3D G3DSA:3.30.470.20 167 385 5.6E-82 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS20580 d91d92d50bef43b4088265d9e4ca7be8 389 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 15 369 39.706 T 06-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 SMD11_RS20580 d91d92d50bef43b4088265d9e4ca7be8 389 Gene3D G3DSA:3.30.1490.20 126 166 1.8E-4 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS20580 d91d92d50bef43b4088265d9e4ca7be8 389 SUPERFAMILY SSF52440 14 107 1.29E-25 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS20580 d91d92d50bef43b4088265d9e4ca7be8 389 SUPERFAMILY SSF51246 316 384 5.49E-17 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS11465 f8801ad7829831a2ffc251c51602f6f0 497 Pfam PF00199 Catalase 21 402 1.3E-187 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS11465 f8801ad7829831a2ffc251c51602f6f0 497 PRINTS PR00067 Catalase signature 302 329 1.2E-67 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS11465 f8801ad7829831a2ffc251c51602f6f0 497 PRINTS PR00067 Catalase signature 137 155 1.2E-67 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS11465 f8801ad7829831a2ffc251c51602f6f0 497 PRINTS PR00067 Catalase signature 97 115 1.2E-67 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS11465 f8801ad7829831a2ffc251c51602f6f0 497 PRINTS PR00067 Catalase signature 34 57 1.2E-67 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS11465 f8801ad7829831a2ffc251c51602f6f0 497 PRINTS PR00067 Catalase signature 334 360 1.2E-67 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS11465 f8801ad7829831a2ffc251c51602f6f0 497 PRINTS PR00067 Catalase signature 118 135 1.2E-67 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS11465 f8801ad7829831a2ffc251c51602f6f0 497 Pfam PF06628 Catalase-related immune-responsive 431 492 9.2E-22 T 06-07-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS11465 f8801ad7829831a2ffc251c51602f6f0 497 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 347 355 - T 06-07-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS11465 f8801ad7829831a2ffc251c51602f6f0 497 Gene3D G3DSA:2.40.180.10 8 371 4.7E-181 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS11465 f8801ad7829831a2ffc251c51602f6f0 497 SMART SM01060 21 405 6.9E-281 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS11465 f8801ad7829831a2ffc251c51602f6f0 497 SUPERFAMILY SSF56634 16 493 3.14E-206 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS11465 f8801ad7829831a2ffc251c51602f6f0 497 ProSitePatterns PS00438 Catalase proximal active site signature. 57 73 - T 06-07-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS11465 f8801ad7829831a2ffc251c51602f6f0 497 PIRSF PIRSF038928 9 496 3.3E-219 T 06-07-2017 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS33745 e9c493a50591613289bb603061d1b5a4 231 Pfam PF13353 4Fe-4S single cluster domain 16 159 3.8E-21 T 06-07-2017 SMD11_RS33745 e9c493a50591613289bb603061d1b5a4 231 SUPERFAMILY SSF102114 26 79 8.76E-9 T 06-07-2017 SMD11_RS33745 e9c493a50591613289bb603061d1b5a4 231 Gene3D G3DSA:3.20.20.70 26 80 1.1E-6 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS21145 8a303e435278d39f570a3474351ef5e7 215 SUPERFAMILY SSF161098 13 198 6.67E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21145 8a303e435278d39f570a3474351ef5e7 215 Gene3D G3DSA:1.10.3720.10 13 201 1.4E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21145 8a303e435278d39f570a3474351ef5e7 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 206 2.2E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 SUPERFAMILY SSF55957 372 452 5.58E-20 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 255 8.3E-26 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 SUPERFAMILY SSF53738 155 257 6.28E-31 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 SUPERFAMILY SSF53738 6 127 6.67E-31 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 SUPERFAMILY SSF53738 261 365 7.85E-31 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 6 130 5.6E-30 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 1.8E-21 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 91 105 1.8E-21 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 219 1.8E-21 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 1.8E-21 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 Gene3D G3DSA:3.40.120.10 174 251 1.3E-32 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 264 369 2.0E-26 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 Gene3D G3DSA:3.40.120.10 252 369 2.8E-38 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 Gene3D G3DSA:3.40.120.10 8 128 1.3E-26 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 Gene3D G3DSA:3.30.310.50 371 451 9.2E-23 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS20715 661e8b3820656c191c599f37f6d0fbb2 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 374 450 1.6E-14 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS26660 43c86cb70bd064f473a599ee01857cb1 455 Gene3D G3DSA:3.40.605.10 5 242 1.9E-89 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS26660 43c86cb70bd064f473a599ee01857cb1 455 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 256 267 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS26660 43c86cb70bd064f473a599ee01857cb1 455 Pfam PF00171 Aldehyde dehydrogenase family 5 447 7.8E-158 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS26660 43c86cb70bd064f473a599ee01857cb1 455 SUPERFAMILY SSF53720 5 449 1.83E-152 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS26660 43c86cb70bd064f473a599ee01857cb1 455 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 228 235 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS26660 43c86cb70bd064f473a599ee01857cb1 455 Gene3D G3DSA:3.40.309.10 243 427 2.4E-59 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS24570 5dc6bc7a5ab04f5ff86574564ab7fb5a 301 SUPERFAMILY SSF109635 171 266 1.57E-9 T 06-07-2017 SMD11_RS24570 5dc6bc7a5ab04f5ff86574564ab7fb5a 301 PRINTS PR00618 DksA/TraR zinc finger signature 270 281 6.0E-5 T 06-07-2017 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria SMD11_RS24570 5dc6bc7a5ab04f5ff86574564ab7fb5a 301 PRINTS PR00618 DksA/TraR zinc finger signature 282 294 6.0E-5 T 06-07-2017 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria SMD11_RS24570 5dc6bc7a5ab04f5ff86574564ab7fb5a 301 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 265 300 2.0E-12 T 06-07-2017 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 SMD11_RS24570 5dc6bc7a5ab04f5ff86574564ab7fb5a 301 SUPERFAMILY SSF57716 267 300 6.65E-9 T 06-07-2017 SMD11_RS24570 5dc6bc7a5ab04f5ff86574564ab7fb5a 301 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 270 294 - T 06-07-2017 IPR020458 Zinc finger, DksA/TraR C4-type conserved site SMD11_RS24105 91c2061cb2300aa5f9c70750408ba515 588 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 251 550 7.4E-111 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal SMD11_RS24105 91c2061cb2300aa5f9c70750408ba515 588 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 30 230 1.2E-9 T 06-07-2017 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 SMD11_RS27735 1b70377ac4e4882bdc5af56c95bd8201 434 Pfam PF01590 GAF domain 113 222 1.3E-4 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS27735 1b70377ac4e4882bdc5af56c95bd8201 434 SMART SM00862 247 312 0.0039 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS04775 e44c30a85ab74d0cb1ba362dc84623b0 341 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 38 56 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 SMD11_RS04775 e44c30a85ab74d0cb1ba362dc84623b0 341 SUPERFAMILY SSF53686 5 319 5.89E-72 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS04775 e44c30a85ab74d0cb1ba362dc84623b0 341 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 15 301 9.0E-57 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS04775 e44c30a85ab74d0cb1ba362dc84623b0 341 Gene3D G3DSA:3.40.50.1100 158 319 1.2E-42 T 06-07-2017 SMD11_RS04775 e44c30a85ab74d0cb1ba362dc84623b0 341 Gene3D G3DSA:3.40.50.1100 9 47 1.2E-42 T 06-07-2017 SMD11_RS04775 e44c30a85ab74d0cb1ba362dc84623b0 341 Gene3D G3DSA:3.40.50.1100 48 138 3.3E-27 T 06-07-2017 SMD11_RS19355 ebbecbd37bc92f195b75fc99e3e0eda4 345 SMART SM00342 247 330 2.3E-25 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS19355 ebbecbd37bc92f195b75fc99e3e0eda4 345 SUPERFAMILY SSF52317 18 213 5.29E-46 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS19355 ebbecbd37bc92f195b75fc99e3e0eda4 345 Pfam PF01965 DJ-1/PfpI family 19 192 8.5E-15 T 06-07-2017 IPR002818 DJ-1/PfpI SMD11_RS19355 ebbecbd37bc92f195b75fc99e3e0eda4 345 Gene3D G3DSA:1.10.10.60 286 334 3.0E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS19355 ebbecbd37bc92f195b75fc99e3e0eda4 345 Gene3D G3DSA:1.10.10.60 235 285 3.0E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS19355 ebbecbd37bc92f195b75fc99e3e0eda4 345 SUPERFAMILY SSF46689 235 281 6.81E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS19355 ebbecbd37bc92f195b75fc99e3e0eda4 345 Gene3D G3DSA:3.40.50.880 20 234 9.8E-49 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS19355 ebbecbd37bc92f195b75fc99e3e0eda4 345 SUPERFAMILY SSF46689 284 335 1.97E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS19355 ebbecbd37bc92f195b75fc99e3e0eda4 345 Pfam PF12833 Helix-turn-helix domain 254 331 2.8E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 SMART SM00341 551 624 7.6E-6 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 SMART SM00956 419 525 2.0E-42 T 06-07-2017 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 Pfam PF00271 Helicase conserved C-terminal domain 232 339 4.5E-15 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 22 474 1.9E-150 T 06-07-2017 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 23 619 2.1E-226 T 06-07-2017 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 Pfam PF00270 DEAD/DEAH box helicase 37 193 2.5E-16 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 SUPERFAMILY SSF52540 15 205 1.28E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 SMART SM00490 258 339 1.0E-23 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 SUPERFAMILY SSF52540 215 466 5.84E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 Pfam PF09382 RQC domain 414 528 5.7E-33 T 06-07-2017 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 Pfam PF16124 RecQ zinc-binding 351 412 1.4E-16 T 06-07-2017 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 Gene3D G3DSA:3.40.50.300 18 210 6.3E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 Gene3D G3DSA:1.10.10.10 353 528 2.7E-51 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 Pfam PF00570 HRDC domain 557 620 8.7E-21 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 Gene3D G3DSA:1.10.150.80 557 616 9.4E-15 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 SUPERFAMILY SSF47819 549 621 1.16E-20 T 06-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 Gene3D G3DSA:3.40.50.300 214 352 2.8E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19620 46d159912272ff533c4ea01b313afcd7 625 SMART SM00487 29 225 2.5E-27 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS14150 62e521c67e12483a9dd95347fc2da349 259 SUPERFAMILY SSF53448 13 250 1.35E-50 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS14150 62e521c67e12483a9dd95347fc2da349 259 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 12 253 29.092 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SMD11_RS14150 62e521c67e12483a9dd95347fc2da349 259 Gene3D G3DSA:3.90.550.10 12 255 1.7E-67 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS14150 62e521c67e12483a9dd95347fc2da349 259 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 15 250 3.4E-68 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SMD11_RS14150 62e521c67e12483a9dd95347fc2da349 259 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 14 251 1.1E-63 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SMD11_RS14150 62e521c67e12483a9dd95347fc2da349 259 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 115 122 - T 06-07-2017 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 SMD11_RS07415 404c15b6dc9d1ebca5d0a7a23fd2fd00 254 Gene3D G3DSA:2.60.130.10 57 251 6.7E-66 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMD11_RS07415 404c15b6dc9d1ebca5d0a7a23fd2fd00 254 SUPERFAMILY SSF49482 58 251 3.79E-61 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMD11_RS07415 404c15b6dc9d1ebca5d0a7a23fd2fd00 254 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 96 124 - T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 SMD11_RS07415 404c15b6dc9d1ebca5d0a7a23fd2fd00 254 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 37 252 3.9E-92 T 06-07-2017 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 SMD11_RS07415 404c15b6dc9d1ebca5d0a7a23fd2fd00 254 Pfam PF00775 Dioxygenase 65 244 5.0E-53 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 SMD11_RS26380 69d6cf412a6ba9e217f6d8fa3292bfe8 409 SUPERFAMILY SSF52374 32 333 3.75E-66 T 06-07-2017 SMD11_RS26380 69d6cf412a6ba9e217f6d8fa3292bfe8 409 Gene3D G3DSA:3.40.50.620 38 326 1.5E-74 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS26380 69d6cf412a6ba9e217f6d8fa3292bfe8 409 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 39 333 1.9E-81 T 06-07-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 SMD11_RS26380 69d6cf412a6ba9e217f6d8fa3292bfe8 409 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 409 54.176 T 06-07-2017 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 SMD11_RS26380 69d6cf412a6ba9e217f6d8fa3292bfe8 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 1.3E-18 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD11_RS26380 69d6cf412a6ba9e217f6d8fa3292bfe8 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 1.3E-18 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD11_RS26380 69d6cf412a6ba9e217f6d8fa3292bfe8 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 210 228 1.3E-18 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD11_RS26380 69d6cf412a6ba9e217f6d8fa3292bfe8 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 241 262 1.3E-18 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD11_RS26380 69d6cf412a6ba9e217f6d8fa3292bfe8 409 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2 409 3.0E-203 T 06-07-2017 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 SMD11_RS27290 de47cfa61b21b823c316b6592a64611f 287 Gene3D G3DSA:3.40.192.10 5 113 2.8E-38 T 06-07-2017 SMD11_RS27290 de47cfa61b21b823c316b6592a64611f 287 SUPERFAMILY SSF53223 7 108 9.21E-27 T 06-07-2017 SMD11_RS27290 de47cfa61b21b823c316b6592a64611f 287 Gene3D G3DSA:3.40.50.720 114 276 4.9E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS27290 de47cfa61b21b823c316b6592a64611f 287 SUPERFAMILY SSF51735 109 271 3.94E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS27290 de47cfa61b21b823c316b6592a64611f 287 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 13 95 2.5E-24 T 06-07-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 SMD11_RS00520 bc9c37417e0cffab6cb91703395636a5 218 Gene3D G3DSA:1.10.10.10 153 213 9.2E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00520 bc9c37417e0cffab6cb91703395636a5 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 2.6E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS00520 bc9c37417e0cffab6cb91703395636a5 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 2.6E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS00520 bc9c37417e0cffab6cb91703395636a5 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 2.6E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS00520 bc9c37417e0cffab6cb91703395636a5 218 SUPERFAMILY SSF52172 1 134 4.84E-19 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS00520 bc9c37417e0cffab6cb91703395636a5 218 SUPERFAMILY SSF46894 139 197 9.86E-13 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS00520 bc9c37417e0cffab6cb91703395636a5 218 Pfam PF00072 Response regulator receiver domain 3 108 8.1E-11 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS00520 bc9c37417e0cffab6cb91703395636a5 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 197 8.6E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS00520 bc9c37417e0cffab6cb91703395636a5 218 SMART SM00421 148 210 6.3E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS00520 bc9c37417e0cffab6cb91703395636a5 218 SMART SM00448 1 120 4.8E-8 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS00520 bc9c37417e0cffab6cb91703395636a5 218 Gene3D G3DSA:3.40.50.2300 1 152 1.1E-22 T 06-07-2017 SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 Pfam PF04073 Aminoacyl-tRNA editing domain 260 373 5.7E-26 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 Gene3D G3DSA:3.90.960.10 256 369 2.9E-18 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 Gene3D G3DSA:3.30.930.10 387 469 4.5E-95 T 06-07-2017 SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 Gene3D G3DSA:3.30.930.10 15 238 4.5E-95 T 06-07-2017 SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 Gene3D G3DSA:3.40.50.800 470 563 5.0E-23 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 SUPERFAMILY SSF52954 462 564 1.18E-24 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 98 456 1.4E-41 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 138 146 3.7E-16 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 108 119 3.7E-16 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 148 159 3.7E-16 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 72 90 3.7E-16 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 6 558 2.2E-169 T 06-07-2017 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 Pfam PF03129 Anticodon binding domain 474 563 3.6E-16 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 SUPERFAMILY SSF55681 405 476 5.17E-87 T 06-07-2017 SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 SUPERFAMILY SSF55681 14 241 5.17E-87 T 06-07-2017 SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 SUPERFAMILY SSF55826 222 386 1.44E-20 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD11_RS09275 0573f739fd62b6d4857ba800ace521fe 565 Hamap MF_01569 Proline--tRNA ligase [proS]. 5 565 36.184 T 06-07-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SMD11_RS27005 ea0b208908e8156570800eacee8ec84d 459 SMART SM00220 17 269 2.7E-46 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS27005 ea0b208908e8156570800eacee8ec84d 459 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 23 45 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS27005 ea0b208908e8156570800eacee8ec84d 459 Gene3D G3DSA:1.10.510.10 99 332 1.3E-41 T 06-07-2017 SMD11_RS27005 ea0b208908e8156570800eacee8ec84d 459 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS27005 ea0b208908e8156570800eacee8ec84d 459 Gene3D G3DSA:3.30.200.20 9 93 1.1E-16 T 06-07-2017 SMD11_RS27005 ea0b208908e8156570800eacee8ec84d 459 SUPERFAMILY SSF56112 13 267 5.33E-63 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS27005 ea0b208908e8156570800eacee8ec84d 459 Pfam PF00069 Protein kinase domain 18 261 1.1E-40 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS24785 4b3097780b5df3f8e06a7e0c373c519a 1524 Pfam PF04898 Glutamate synthase central domain 464 754 4.8E-111 T 06-07-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 SMD11_RS24785 4b3097780b5df3f8e06a7e0c373c519a 1524 SUPERFAMILY SSF69336 1232 1497 6.8E-89 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD11_RS24785 4b3097780b5df3f8e06a7e0c373c519a 1524 Gene3D G3DSA:3.20.20.70 835 1216 8.5E-178 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS24785 4b3097780b5df3f8e06a7e0c373c519a 1524 Gene3D G3DSA:2.160.20.60 1238 1512 1.8E-104 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD11_RS24785 4b3097780b5df3f8e06a7e0c373c519a 1524 SUPERFAMILY SSF56235 22 439 1.08E-146 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS24785 4b3097780b5df3f8e06a7e0c373c519a 1524 Pfam PF01645 Conserved region in glutamate synthase 821 1183 1.3E-154 T 06-07-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 SMD11_RS24785 4b3097780b5df3f8e06a7e0c373c519a 1524 Gene3D G3DSA:3.20.20.70 448 807 8.8E-103 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS24785 4b3097780b5df3f8e06a7e0c373c519a 1524 Gene3D G3DSA:3.60.20.10 22 447 1.1E-182 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS24785 4b3097780b5df3f8e06a7e0c373c519a 1524 Pfam PF00310 Glutamine amidotransferases class-II 22 437 2.0E-177 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain SMD11_RS24785 4b3097780b5df3f8e06a7e0c373c519a 1524 Pfam PF01493 GXGXG motif 1268 1441 2.5E-77 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD11_RS24785 4b3097780b5df3f8e06a7e0c373c519a 1524 SUPERFAMILY SSF51395 452 1219 1.18E-260 T 06-07-2017 SMD11_RS28360 92e285ffa4d63840a6fc6919dbfd1d4c 317 SUPERFAMILY SSF50249 206 313 1.54E-21 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS28360 92e285ffa4d63840a6fc6919dbfd1d4c 317 Gene3D G3DSA:2.40.50.140 207 314 1.0E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS28360 92e285ffa4d63840a6fc6919dbfd1d4c 317 Gene3D G3DSA:3.30.470.30 36 149 8.3E-28 T 06-07-2017 SMD11_RS28360 92e285ffa4d63840a6fc6919dbfd1d4c 317 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 23 313 4.3E-74 T 06-07-2017 IPR014146 DNA ligase D, ligase domain SMD11_RS28360 92e285ffa4d63840a6fc6919dbfd1d4c 317 Pfam PF01068 ATP dependent DNA ligase domain 25 203 5.0E-29 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 SMD11_RS28360 92e285ffa4d63840a6fc6919dbfd1d4c 317 Gene3D G3DSA:3.30.1490.70 7 35 4.7E-18 T 06-07-2017 SMD11_RS28360 92e285ffa4d63840a6fc6919dbfd1d4c 317 Gene3D G3DSA:3.30.1490.70 160 204 4.7E-18 T 06-07-2017 SMD11_RS28360 92e285ffa4d63840a6fc6919dbfd1d4c 317 SUPERFAMILY SSF56091 8 203 1.85E-43 T 06-07-2017 SMD11_RS28360 92e285ffa4d63840a6fc6919dbfd1d4c 317 Pfam PF04679 ATP dependent DNA ligase C terminal region 225 313 4.1E-20 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 SMD11_RS04875 7ffd2535322b33f19b6a46cb10c74b39 506 SUPERFAMILY SSF53474 403 472 2.83E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04875 7ffd2535322b33f19b6a46cb10c74b39 506 SUPERFAMILY SSF53474 76 142 2.83E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04875 7ffd2535322b33f19b6a46cb10c74b39 506 SUPERFAMILY SSF53474 174 242 2.83E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04875 7ffd2535322b33f19b6a46cb10c74b39 506 SUPERFAMILY SSF53474 322 348 2.83E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04875 7ffd2535322b33f19b6a46cb10c74b39 506 Pfam PF00561 alpha/beta hydrolase fold 97 277 1.4E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS04875 7ffd2535322b33f19b6a46cb10c74b39 506 Gene3D G3DSA:3.40.50.1820 187 311 1.3E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04875 7ffd2535322b33f19b6a46cb10c74b39 506 Gene3D G3DSA:3.40.50.1820 371 483 1.3E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04875 7ffd2535322b33f19b6a46cb10c74b39 506 Gene3D G3DSA:3.40.50.1820 62 147 1.3E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04875 7ffd2535322b33f19b6a46cb10c74b39 506 Pfam PF08386 TAP-like protein 406 500 2.8E-22 T 06-07-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMD11_RS11290 6863bf6ff4b0399a20f9b3a319a78188 255 Pfam PF07702 UTRA domain 105 245 5.5E-42 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS11290 6863bf6ff4b0399a20f9b3a319a78188 255 SMART SM00866 105 245 1.2E-42 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS11290 6863bf6ff4b0399a20f9b3a319a78188 255 Gene3D G3DSA:1.10.10.10 19 82 9.9E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11290 6863bf6ff4b0399a20f9b3a319a78188 255 SUPERFAMILY SSF64288 73 252 1.73E-54 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS11290 6863bf6ff4b0399a20f9b3a319a78188 255 SUPERFAMILY SSF46785 19 89 3.08E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11290 6863bf6ff4b0399a20f9b3a319a78188 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 2.6E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS11290 6863bf6ff4b0399a20f9b3a319a78188 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 2.6E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS11290 6863bf6ff4b0399a20f9b3a319a78188 255 Gene3D G3DSA:3.40.1410.10 83 252 1.1E-55 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS11290 6863bf6ff4b0399a20f9b3a319a78188 255 Pfam PF00392 Bacterial regulatory proteins, gntR family 36 85 1.4E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS11290 6863bf6ff4b0399a20f9b3a319a78188 255 SMART SM00345 28 85 1.3E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS26095 9a5888b228ab0bd405232eec8494411f 395 Gene3D G3DSA:3.20.20.10 28 263 2.0E-57 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS26095 9a5888b228ab0bd405232eec8494411f 395 SUPERFAMILY SSF50621 239 391 2.72E-33 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS26095 9a5888b228ab0bd405232eec8494411f 395 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 264 283 2.2E-9 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS26095 9a5888b228ab0bd405232eec8494411f 395 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 67 79 2.2E-9 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS26095 9a5888b228ab0bd405232eec8494411f 395 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 47 65 2.2E-9 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS26095 9a5888b228ab0bd405232eec8494411f 395 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 182 195 2.2E-9 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS26095 9a5888b228ab0bd405232eec8494411f 395 Gene3D G3DSA:2.40.37.10 264 392 9.2E-25 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS26095 9a5888b228ab0bd405232eec8494411f 395 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 279 389 8.8E-9 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMD11_RS26095 9a5888b228ab0bd405232eec8494411f 395 SUPERFAMILY SSF51419 24 277 5.23E-55 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS26095 9a5888b228ab0bd405232eec8494411f 395 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 35 275 4.9E-28 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMD11_RS30905 cc1f415fd89a6b71627398845a899b00 240 Gene3D G3DSA:3.40.50.150 194 213 1.3E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS30905 cc1f415fd89a6b71627398845a899b00 240 Gene3D G3DSA:3.40.50.150 37 160 1.3E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS30905 cc1f415fd89a6b71627398845a899b00 240 Pfam PF13489 Methyltransferase domain 39 213 5.6E-14 T 06-07-2017 SMD11_RS30905 cc1f415fd89a6b71627398845a899b00 240 SUPERFAMILY SSF53335 43 216 1.17E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS25205 df83a9fdff64c907bad3650ac452f9ee 269 SUPERFAMILY SSF46785 40 228 4.1E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS25205 df83a9fdff64c907bad3650ac452f9ee 269 Pfam PF01022 Bacterial regulatory protein, arsR family 40 84 1.5E-7 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS25205 df83a9fdff64c907bad3650ac452f9ee 269 Gene3D G3DSA:1.10.10.10 41 137 6.0E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Gene3D G3DSA:3.30.70.250 659 716 2.4E-5 T 06-07-2017 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SUPERFAMILY SSF50129 1909 2044 2.04E-29 T 06-07-2017 IPR011032 GroES-like SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 2046 2067 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2249 2429 7.5E-36 T 06-07-2017 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 536 836 8.8E-101 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SUPERFAMILY SSF51735 2018 2175 4.27E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Gene3D G3DSA:3.40.50.720 2053 2144 7.9E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 266 383 3.7E-36 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SUPERFAMILY SSF47336 2525 2604 3.4E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SMART SM00829 1916 2228 2.2E-136 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SUPERFAMILY SSF53335 1396 1566 1.52E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Pfam PF00550 Phosphopantetheine attachment site 2534 2598 4.5E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SUPERFAMILY SSF51735 2249 2476 2.21E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Gene3D G3DSA:1.10.1200.10 2526 2604 5.7E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SMART SM00826 900 1059 3.0E-33 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Pfam PF14765 Polyketide synthase dehydratase 900 1192 9.0E-60 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Gene3D G3DSA:3.40.50.150 1405 1563 3.0E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1931 1995 7.9E-5 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Gene3D G3DSA:3.40.47.10 272 435 9.0E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2557 2572 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 10 257 3.4E-78 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Gene3D G3DSA:3.40.366.10 531 656 6.6E-69 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Gene3D G3DSA:3.40.366.10 724 837 6.6E-69 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Pfam PF08242 Methyltransferase domain 1412 1512 1.7E-16 T 06-07-2017 IPR013217 Methyltransferase type 12 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Pfam PF08659 KR domain 2249 2427 4.1E-53 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SUPERFAMILY SSF52151 726 819 1.07E-65 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SUPERFAMILY SSF52151 533 662 1.07E-65 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 388 474 1.2E-16 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Gene3D G3DSA:3.90.180.10 1913 2052 2.5E-40 T 06-07-2017 IPR011032 GroES-like SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SMART SM00825 Beta-ketoacyl synthase 12 435 1.1E-172 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SMART SM00823 Phosphopantetheine attachment site 2531 2602 4.5E-11 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Pfam PF00698 Acyl transferase domain 535 850 1.4E-73 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SUPERFAMILY SSF51735 1685 1895 9.65E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Gene3D G3DSA:3.40.47.10 9 270 3.6E-89 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SUPERFAMILY SSF55048 660 724 3.92E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SUPERFAMILY SSF53901 8 379 5.14E-88 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 SUPERFAMILY SSF53901 411 430 5.14E-88 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Gene3D G3DSA:3.40.50.720 2250 2426 6.4E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29705 68633f00a1e6a11e86383b8a0a2327d3 2609 Pfam PF00107 Zinc-binding dehydrogenase 2057 2149 7.5E-26 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS18935 419fac9596773017273a08ef0ffaed11 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 06-07-2017 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18935 419fac9596773017273a08ef0ffaed11 122 Gene3D G3DSA:2.40.150.20 2 122 1.5E-53 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SMD11_RS18935 419fac9596773017273a08ef0ffaed11 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 4.4E-57 T 06-07-2017 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 SMD11_RS18935 419fac9596773017273a08ef0ffaed11 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 6.0E-54 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SMD11_RS18935 419fac9596773017273a08ef0ffaed11 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.021 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SMD11_RS18935 419fac9596773017273a08ef0ffaed11 122 SMART SM01374 1 122 2.4E-87 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SMD11_RS18935 419fac9596773017273a08ef0ffaed11 122 SUPERFAMILY SSF50193 2 122 2.62E-50 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SMD11_RS06445 defcf394f8498087b0dde2ba0c56653b 274 Gene3D G3DSA:3.60.15.10 26 262 4.5E-32 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS06445 defcf394f8498087b0dde2ba0c56653b 274 SUPERFAMILY SSF56281 26 263 8.65E-29 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS06445 defcf394f8498087b0dde2ba0c56653b 274 Pfam PF00753 Metallo-beta-lactamase superfamily 31 220 8.0E-16 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS06445 defcf394f8498087b0dde2ba0c56653b 274 SMART SM00849 32 261 1.1E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS12230 74af8864d0a704dfd48c458a072dccb1 184 PIRSF PIRSF000239 1 184 9.8E-51 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMD11_RS12230 74af8864d0a704dfd48c458a072dccb1 184 SUPERFAMILY SSF52833 2 177 5.26E-55 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS12230 74af8864d0a704dfd48c458a072dccb1 184 Pfam PF00578 AhpC/TSA family 4 136 4.7E-34 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMD11_RS12230 74af8864d0a704dfd48c458a072dccb1 184 Gene3D G3DSA:3.40.30.10 2 177 4.2E-63 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS15740 f8d752b668c1f84bed61cec061027397 300 SUPERFAMILY SSF53850 97 291 6.15E-23 T 06-07-2017 SMD11_RS15740 f8d752b668c1f84bed61cec061027397 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 66 5.7E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS15740 f8d752b668c1f84bed61cec061027397 300 Pfam PF03466 LysR substrate binding domain 96 289 2.1E-22 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS15740 f8d752b668c1f84bed61cec061027397 300 Gene3D G3DSA:3.40.190.10 95 209 5.8E-20 T 06-07-2017 SMD11_RS15740 f8d752b668c1f84bed61cec061027397 300 SUPERFAMILY SSF46785 7 119 2.01E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15740 f8d752b668c1f84bed61cec061027397 300 Gene3D G3DSA:1.10.10.10 9 89 8.9E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15740 f8d752b668c1f84bed61cec061027397 300 Gene3D G3DSA:3.40.190.10 210 264 1.1E-6 T 06-07-2017 SMD11_RS21890 7e9d5a826e37595c9cfb4d6e627c5fef 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 119 3.1E-5 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS21890 7e9d5a826e37595c9cfb4d6e627c5fef 131 Gene3D G3DSA:3.10.180.10 4 126 1.1E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS21890 7e9d5a826e37595c9cfb4d6e627c5fef 131 SUPERFAMILY SSF54593 5 124 7.75E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS00915 cebd42cfb601c00d840b4c4c249b8b80 519 PIRSF PIRSF001220 177 392 1.3E-50 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 SMD11_RS00915 cebd42cfb601c00d840b4c4c249b8b80 519 PRINTS PR00139 Asparaginase/glutaminase family signature 183 194 5.1E-7 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 SMD11_RS00915 cebd42cfb601c00d840b4c4c249b8b80 519 PRINTS PR00139 Asparaginase/glutaminase family signature 256 274 5.1E-7 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 SMD11_RS00915 cebd42cfb601c00d840b4c4c249b8b80 519 SMART SM00870 182 441 9.3E-35 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 SMD11_RS00915 cebd42cfb601c00d840b4c4c249b8b80 519 Gene3D G3DSA:3.40.50.1170 182 372 5.1E-46 T 06-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 SMD11_RS00915 cebd42cfb601c00d840b4c4c249b8b80 519 Pfam PF00710 Asparaginase, N-terminal 183 366 1.4E-42 T 06-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 SMD11_RS00915 cebd42cfb601c00d840b4c4c249b8b80 519 PIRSF PIRSF500176 179 393 5.1E-48 T 06-07-2017 SMD11_RS00915 cebd42cfb601c00d840b4c4c249b8b80 519 SUPERFAMILY SSF53774 182 373 3.01E-49 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 SMD11_RS11820 8f9f96825eaa3eaeefa44c991db0c8ed 638 Gene3D G3DSA:2.40.10.10 345 424 1.7E-27 T 06-07-2017 SMD11_RS11820 8f9f96825eaa3eaeefa44c991db0c8ed 638 SMART SM00228 544 623 4.2E-9 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS11820 8f9f96825eaa3eaeefa44c991db0c8ed 638 Gene3D G3DSA:2.30.42.10 547 634 1.5E-18 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS11820 8f9f96825eaa3eaeefa44c991db0c8ed 638 SUPERFAMILY SSF50156 525 631 1.97E-18 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS11820 8f9f96825eaa3eaeefa44c991db0c8ed 638 Gene3D G3DSA:2.40.10.10 425 546 3.0E-42 T 06-07-2017 SMD11_RS11820 8f9f96825eaa3eaeefa44c991db0c8ed 638 PRINTS PR00834 HtrA/DegQ protease family signature 424 448 1.1E-40 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS11820 8f9f96825eaa3eaeefa44c991db0c8ed 638 PRINTS PR00834 HtrA/DegQ protease family signature 489 506 1.1E-40 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS11820 8f9f96825eaa3eaeefa44c991db0c8ed 638 PRINTS PR00834 HtrA/DegQ protease family signature 581 593 1.1E-40 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS11820 8f9f96825eaa3eaeefa44c991db0c8ed 638 PRINTS PR00834 HtrA/DegQ protease family signature 359 371 1.1E-40 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS11820 8f9f96825eaa3eaeefa44c991db0c8ed 638 PRINTS PR00834 HtrA/DegQ protease family signature 383 403 1.1E-40 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS11820 8f9f96825eaa3eaeefa44c991db0c8ed 638 PRINTS PR00834 HtrA/DegQ protease family signature 467 484 1.1E-40 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS11820 8f9f96825eaa3eaeefa44c991db0c8ed 638 SUPERFAMILY SSF50494 320 549 1.71E-54 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS11820 8f9f96825eaa3eaeefa44c991db0c8ed 638 Pfam PF13365 Trypsin-like peptidase domain 350 496 1.6E-32 T 06-07-2017 SMD11_RS11820 8f9f96825eaa3eaeefa44c991db0c8ed 638 Pfam PF13180 PDZ domain 544 632 1.1E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS21160 e2eb087eee8cea1e57c46c9fd8ed8748 455 SUPERFAMILY SSF55103 191 454 3.43E-62 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 SMD11_RS21160 e2eb087eee8cea1e57c46c9fd8ed8748 455 Gene3D G3DSA:3.30.43.10 3 94 1.4E-23 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS21160 e2eb087eee8cea1e57c46c9fd8ed8748 455 Gene3D G3DSA:1.10.45.10 415 454 1.5E-14 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 SMD11_RS21160 e2eb087eee8cea1e57c46c9fd8ed8748 455 Pfam PF01565 FAD binding domain 41 179 3.1E-39 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD11_RS21160 e2eb087eee8cea1e57c46c9fd8ed8748 455 SUPERFAMILY SSF56176 3 216 6.07E-68 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS21160 e2eb087eee8cea1e57c46c9fd8ed8748 455 Pfam PF02913 FAD linked oxidases, C-terminal domain 221 454 3.1E-68 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 SMD11_RS21160 e2eb087eee8cea1e57c46c9fd8ed8748 455 Gene3D G3DSA:3.30.465.10 95 216 4.5E-43 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS34090 ff1ab92354e33f223ed2a577da07fc76 489 SUPERFAMILY SSF48239 233 451 2.92E-13 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS34090 ff1ab92354e33f223ed2a577da07fc76 489 SUPERFAMILY SSF48239 17 86 2.67E-8 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS34090 ff1ab92354e33f223ed2a577da07fc76 489 SUPERFAMILY SSF48239 166 299 2.67E-8 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS34090 ff1ab92354e33f223ed2a577da07fc76 489 Gene3D G3DSA:1.50.10.20 254 452 8.7E-14 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS34090 ff1ab92354e33f223ed2a577da07fc76 489 Gene3D G3DSA:1.50.10.20 29 83 8.7E-14 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS19430 d6f71a528d0a5e71aef92c81533e6d88 561 Gene3D G3DSA:3.30.300.30 448 546 5.7E-30 T 06-07-2017 SMD11_RS19430 d6f71a528d0a5e71aef92c81533e6d88 561 Pfam PF13193 AMP-binding enzyme C-terminal domain 462 538 1.5E-20 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS19430 d6f71a528d0a5e71aef92c81533e6d88 561 Gene3D G3DSA:2.30.38.10 371 444 1.2E-27 T 06-07-2017 SMD11_RS19430 d6f71a528d0a5e71aef92c81533e6d88 561 ProSitePatterns PS00455 Putative AMP-binding domain signature. 204 215 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS19430 d6f71a528d0a5e71aef92c81533e6d88 561 SUPERFAMILY SSF56801 6 547 6.02E-143 T 06-07-2017 SMD11_RS19430 d6f71a528d0a5e71aef92c81533e6d88 561 Gene3D G3DSA:3.40.50.980 9 211 5.7E-32 T 06-07-2017 SMD11_RS19430 d6f71a528d0a5e71aef92c81533e6d88 561 Gene3D G3DSA:3.40.50.980 212 363 6.3E-37 T 06-07-2017 SMD11_RS19430 d6f71a528d0a5e71aef92c81533e6d88 561 Pfam PF00501 AMP-binding enzyme 15 453 1.5E-97 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 Pfam PF14684 Tricorn protease C1 domain 706 772 1.5E-26 T 06-07-2017 IPR028204 Tricorn protease C1 domain SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 SMART SM00245 869 1061 3.0E-12 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 SUPERFAMILY SSF50156 788 868 7.42E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 Gene3D G3DSA:2.120.10.60 8 265 4.3E-57 T 06-07-2017 SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 Gene3D G3DSA:2.30.42.10 787 882 3.8E-28 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 Pfam PF07676 WD40-like Beta Propeller Repeat 66 83 0.011 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 Pfam PF07676 WD40-like Beta Propeller Repeat 495 527 0.0018 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 SUPERFAMILY SSF52096 878 1086 7.62E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 SUPERFAMILY SSF52096 703 782 7.62E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 SUPERFAMILY SSF69304 14 278 5.23E-23 T 06-07-2017 SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 Gene3D G3DSA:3.30.750.44 703 773 5.1E-31 T 06-07-2017 SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 Pfam PF03572 Peptidase family S41 905 1060 3.9E-23 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 SUPERFAMILY SSF69304 633 679 6.15E-18 T 06-07-2017 SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 SUPERFAMILY SSF69304 376 529 6.15E-18 T 06-07-2017 SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 Pfam PF14685 Tricorn protease PDZ domain 788 876 1.4E-23 T 06-07-2017 IPR029414 Tricorn protease, PDZ domain SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 Gene3D G3DSA:2.130.10.10 360 694 2.8E-86 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 Gene3D G3DSA:2.130.10.10 266 294 2.8E-86 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 PIRSF PIRSF036421 5 1094 0.0 T 06-07-2017 IPR012393 Tricorn protease GO:0008236 SMD11_RS19985 b221d76a7c0ebca90c1771436c6af8b3 1112 Gene3D G3DSA:3.90.226.10 885 1090 9.1E-39 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS01710 af8c0b8e6718e8fc950619916ad3c365 311 Gene3D G3DSA:1.10.10.10 2 84 1.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01710 af8c0b8e6718e8fc950619916ad3c365 311 Pfam PF03466 LysR substrate binding domain 151 294 3.0E-10 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS01710 af8c0b8e6718e8fc950619916ad3c365 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 5.9E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS01710 af8c0b8e6718e8fc950619916ad3c365 311 Gene3D G3DSA:3.40.190.10 271 298 1.2E-15 T 06-07-2017 SMD11_RS01710 af8c0b8e6718e8fc950619916ad3c365 311 Gene3D G3DSA:3.40.190.10 90 172 1.2E-15 T 06-07-2017 SMD11_RS01710 af8c0b8e6718e8fc950619916ad3c365 311 SUPERFAMILY SSF53850 90 293 7.6E-26 T 06-07-2017 SMD11_RS01710 af8c0b8e6718e8fc950619916ad3c365 311 Gene3D G3DSA:3.40.190.10 173 265 1.0E-16 T 06-07-2017 SMD11_RS01710 af8c0b8e6718e8fc950619916ad3c365 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 3.7E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS01710 af8c0b8e6718e8fc950619916ad3c365 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 3.7E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS01710 af8c0b8e6718e8fc950619916ad3c365 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 3.7E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS01710 af8c0b8e6718e8fc950619916ad3c365 311 SUPERFAMILY SSF46785 3 84 2.45E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS09770 0c26144c296baafc608571315deda2d2 333 SUPERFAMILY SSF48179 179 331 2.58E-55 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS09770 0c26144c296baafc608571315deda2d2 333 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 322 37.624 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 SMD11_RS09770 0c26144c296baafc608571315deda2d2 333 Gene3D G3DSA:3.40.50.720 3 183 1.1E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS09770 0c26144c296baafc608571315deda2d2 333 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 4 160 1.5E-52 T 06-07-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 SMD11_RS09770 0c26144c296baafc608571315deda2d2 333 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 180 317 7.4E-50 T 06-07-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 SMD11_RS09770 0c26144c296baafc608571315deda2d2 333 Gene3D G3DSA:1.10.1040.10 184 326 1.8E-55 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS09770 0c26144c296baafc608571315deda2d2 333 PIRSF PIRSF000114 1 332 1.1E-100 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 SMD11_RS09770 0c26144c296baafc608571315deda2d2 333 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 188 209 - T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 SMD11_RS09770 0c26144c296baafc608571315deda2d2 333 SUPERFAMILY SSF51735 3 180 1.4E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS09770 0c26144c296baafc608571315deda2d2 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 2.4E-45 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 SMD11_RS09770 0c26144c296baafc608571315deda2d2 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 198 222 2.4E-45 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 SMD11_RS09770 0c26144c296baafc608571315deda2d2 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 238 255 2.4E-45 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 SMD11_RS09770 0c26144c296baafc608571315deda2d2 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 2.4E-45 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 SMD11_RS09770 0c26144c296baafc608571315deda2d2 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 133 153 2.4E-45 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 SMD11_RS09770 0c26144c296baafc608571315deda2d2 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 173 197 2.4E-45 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 SMD11_RS19665 87d59fe123d75ee973495fc91714a808 214 SUPERFAMILY SSF46689 8 89 1.5E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS19665 87d59fe123d75ee973495fc91714a808 214 SUPERFAMILY SSF48498 85 193 5.56E-25 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS19665 87d59fe123d75ee973495fc91714a808 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 5.5E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS19665 87d59fe123d75ee973495fc91714a808 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 5.7E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS19665 87d59fe123d75ee973495fc91714a808 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 5.7E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS19665 87d59fe123d75ee973495fc91714a808 214 Gene3D G3DSA:1.10.357.10 8 199 1.0E-37 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS28690 273f60f89c84d2e92d014ac07097f27e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28690 273f60f89c84d2e92d014ac07097f27e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28690 273f60f89c84d2e92d014ac07097f27e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28690 273f60f89c84d2e92d014ac07097f27e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 3.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28690 273f60f89c84d2e92d014ac07097f27e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28690 273f60f89c84d2e92d014ac07097f27e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28690 273f60f89c84d2e92d014ac07097f27e 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 248 2.7E-55 T 06-07-2017 SMD11_RS28690 273f60f89c84d2e92d014ac07097f27e 248 Gene3D G3DSA:3.40.50.720 2 247 2.4E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS28690 273f60f89c84d2e92d014ac07097f27e 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28690 273f60f89c84d2e92d014ac07097f27e 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28690 273f60f89c84d2e92d014ac07097f27e 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28690 273f60f89c84d2e92d014ac07097f27e 248 SUPERFAMILY SSF51735 2 248 6.77E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32490 98b8d050b52cd9eda3e0732710222bb3 171 Gene3D G3DSA:3.40.630.30 13 169 1.7E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS32490 98b8d050b52cd9eda3e0732710222bb3 171 Pfam PF13302 Acetyltransferase (GNAT) domain 10 147 1.6E-17 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS32490 98b8d050b52cd9eda3e0732710222bb3 171 SUPERFAMILY SSF55729 7 160 3.06E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS19585 9b7e38cd97a433ad66e772e51ab8af63 206 Pfam PF00069 Protein kinase domain 8 203 1.0E-24 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS19585 9b7e38cd97a433ad66e772e51ab8af63 206 SMART SM00220 1 205 1.3E-8 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS19585 9b7e38cd97a433ad66e772e51ab8af63 206 Gene3D G3DSA:1.10.510.10 128 202 4.2E-22 T 06-07-2017 SMD11_RS19585 9b7e38cd97a433ad66e772e51ab8af63 206 SUPERFAMILY SSF56112 2 203 6.29E-37 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS19585 9b7e38cd97a433ad66e772e51ab8af63 206 Gene3D G3DSA:3.30.200.20 3 127 4.1E-12 T 06-07-2017 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 Gene3D G3DSA:3.40.1110.10 524 636 8.7E-26 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 Pfam PF00122 E1-E2 ATPase 280 501 1.2E-68 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 Gene3D G3DSA:2.60.40.420 38 122 6.4E-4 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 358 372 7.9E-27 T 06-07-2017 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 510 524 7.9E-27 T 06-07-2017 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 732 744 7.9E-27 T 06-07-2017 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 656 666 7.9E-27 T 06-07-2017 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 709 728 7.9E-27 T 06-07-2017 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 634 645 7.9E-27 T 06-07-2017 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 Gene3D G3DSA:3.40.50.1000 637 777 5.1E-55 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 Gene3D G3DSA:3.40.50.1000 481 523 5.1E-55 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 Pfam PF00702 haloacid dehalogenase-like hydrolase 507 723 4.3E-41 T 06-07-2017 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 SUPERFAMILY SSF49503 21 122 3.13E-8 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 Gene3D G3DSA:2.70.150.10 244 409 1.8E-33 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 512 518 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 241 818 6.5E-193 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 280 789 3.2E-89 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 SUPERFAMILY SSF56784 567 815 1.46E-55 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 SUPERFAMILY SSF56784 508 528 1.46E-55 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 Pfam PF13473 Cupredoxin-like domain 16 122 1.6E-12 T 06-07-2017 IPR028096 EfeO-type cupredoxin-like domain SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 SUPERFAMILY SSF81653 312 408 1.96E-29 T 06-07-2017 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 223 819 3.0E-183 T 06-07-2017 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 SUPERFAMILY SSF81665 278 312 1.11E-14 T 06-07-2017 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 SUPERFAMILY SSF81665 409 504 1.11E-14 T 06-07-2017 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 SUPERFAMILY SSF81665 758 798 1.11E-14 T 06-07-2017 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 681 697 7.0E-11 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 709 725 7.0E-11 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS05120 554e954a2ad61586c809a789d1c3ddd7 832 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 740 765 7.0E-11 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS34100 0f805da6afb7747a5f46cc808c3c9003 475 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 414 423 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS34100 0f805da6afb7747a5f46cc808c3c9003 475 Gene3D G3DSA:1.10.630.10 40 474 1.9E-103 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS34100 0f805da6afb7747a5f46cc808c3c9003 475 PRINTS PR00463 E-class P450 group I signature 274 291 1.2E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS34100 0f805da6afb7747a5f46cc808c3c9003 475 PRINTS PR00463 E-class P450 group I signature 294 320 1.2E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS34100 0f805da6afb7747a5f46cc808c3c9003 475 PRINTS PR00463 E-class P450 group I signature 421 444 1.2E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS34100 0f805da6afb7747a5f46cc808c3c9003 475 PRINTS PR00463 E-class P450 group I signature 411 421 1.2E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS34100 0f805da6afb7747a5f46cc808c3c9003 475 PRINTS PR00463 E-class P450 group I signature 63 82 1.2E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS34100 0f805da6afb7747a5f46cc808c3c9003 475 PRINTS PR00463 E-class P450 group I signature 376 400 1.2E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS34100 0f805da6afb7747a5f46cc808c3c9003 475 Pfam PF00067 Cytochrome P450 40 455 9.1E-74 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS34100 0f805da6afb7747a5f46cc808c3c9003 475 SUPERFAMILY SSF48264 40 473 5.76E-95 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS34100 0f805da6afb7747a5f46cc808c3c9003 475 PRINTS PR00385 P450 superfamily signature 285 302 6.4E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS34100 0f805da6afb7747a5f46cc808c3c9003 475 PRINTS PR00385 P450 superfamily signature 421 432 6.4E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS34100 0f805da6afb7747a5f46cc808c3c9003 475 PRINTS PR00385 P450 superfamily signature 337 348 6.4E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS34100 0f805da6afb7747a5f46cc808c3c9003 475 PRINTS PR00385 P450 superfamily signature 412 421 6.4E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 SUPERFAMILY SSF82171 351 624 7.85E-40 T 06-07-2017 SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 Gene3D G3DSA:3.20.20.140 699 975 4.5E-25 T 06-07-2017 SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 Pfam PF01979 Amidohydrolase family 938 1019 5.4E-11 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 Pfam PF07676 WD40-like Beta Propeller Repeat 207 226 1.5E-5 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 Pfam PF07676 WD40-like Beta Propeller Repeat 549 569 0.025 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 Pfam PF07676 WD40-like Beta Propeller Repeat 107 130 0.0017 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 Pfam PF07676 WD40-like Beta Propeller Repeat 412 430 0.11 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 Pfam PF07676 WD40-like Beta Propeller Repeat 138 170 6.1E-9 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 Pfam PF07676 WD40-like Beta Propeller Repeat 498 511 0.0015 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 Pfam PF07676 WD40-like Beta Propeller Repeat 597 612 0.073 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 Gene3D G3DSA:2.30.40.10 976 1002 6.1E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 SUPERFAMILY SSF82171 368 451 2.28E-34 T 06-07-2017 SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 SUPERFAMILY SSF82171 67 308 2.28E-34 T 06-07-2017 SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 Gene3D G3DSA:2.30.40.10 639 698 1.4E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 Gene3D G3DSA:2.30.40.10 1003 1032 1.4E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 SUPERFAMILY SSF51338 993 1016 5.28E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 SUPERFAMILY SSF51338 635 697 5.28E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 Gene3D G3DSA:2.120.10.60 54 278 4.8E-40 T 06-07-2017 SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 Gene3D G3DSA:2.120.10.60 365 631 1.9E-44 T 06-07-2017 SMD11_RS05245 f5d933bda88c2dedd7c957bf8935a9ea 1075 SUPERFAMILY SSF51556 696 994 7.85E-37 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS33180 4f39b4c244ab095d1d8a0a8a2e7983d6 579 PIRSF PIRSF001589 1 578 3.5E-99 T 06-07-2017 SMD11_RS33180 4f39b4c244ab095d1d8a0a8a2e7983d6 579 SUPERFAMILY SSF52402 430 575 5.29E-49 T 06-07-2017 SMD11_RS33180 4f39b4c244ab095d1d8a0a8a2e7983d6 579 SUPERFAMILY SSF52402 233 373 5.29E-49 T 06-07-2017 SMD11_RS33180 4f39b4c244ab095d1d8a0a8a2e7983d6 579 SUPERFAMILY SSF56235 2 216 1.8E-40 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS33180 4f39b4c244ab095d1d8a0a8a2e7983d6 579 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 16 513 3.0E-85 T 06-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SMD11_RS33180 4f39b4c244ab095d1d8a0a8a2e7983d6 579 Pfam PF13537 Glutamine amidotransferase domain 45 163 1.9E-30 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain SMD11_RS33180 4f39b4c244ab095d1d8a0a8a2e7983d6 579 Gene3D G3DSA:3.40.50.620 437 572 8.6E-53 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS33180 4f39b4c244ab095d1d8a0a8a2e7983d6 579 Gene3D G3DSA:3.40.50.620 226 379 8.6E-53 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS33180 4f39b4c244ab095d1d8a0a8a2e7983d6 579 Gene3D G3DSA:3.60.20.10 2 216 8.4E-45 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS33180 4f39b4c244ab095d1d8a0a8a2e7983d6 579 Pfam PF00733 Asparagine synthase 234 576 4.0E-56 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMD11_RS18645 e677a6e2f711abd611d43cff86ba2593 307 Pfam PF12679 ABC-2 family transporter protein 104 244 3.8E-11 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 SMD11_RS31135 8e015956c319cd25ed064ef06fb56736 332 Gene3D G3DSA:1.10.10.60 100 161 2.0E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS31135 8e015956c319cd25ed064ef06fb56736 332 SUPERFAMILY SSF46689 104 166 2.92E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS31135 8e015956c319cd25ed064ef06fb56736 332 SUPERFAMILY SSF48498 281 326 4.11E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS31135 8e015956c319cd25ed064ef06fb56736 332 SUPERFAMILY SSF48498 176 250 4.11E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS31135 8e015956c319cd25ed064ef06fb56736 332 SMART SM00345 12 71 2.2E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS31135 8e015956c319cd25ed064ef06fb56736 332 Gene3D G3DSA:1.10.357.10 162 324 1.8E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS31135 8e015956c319cd25ed064ef06fb56736 332 Gene3D G3DSA:1.10.10.10 4 73 1.0E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS31135 8e015956c319cd25ed064ef06fb56736 332 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 172 323 4.9E-16 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD11_RS31135 8e015956c319cd25ed064ef06fb56736 332 Pfam PF00440 Bacterial regulatory proteins, tetR family 116 156 4.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS31135 8e015956c319cd25ed064ef06fb56736 332 SUPERFAMILY SSF46785 4 92 4.08E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS31135 8e015956c319cd25ed064ef06fb56736 332 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 71 6.1E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 PIRSF PIRSF000530 1 390 1.1E-108 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 Pfam PF08544 GHMP kinases C terminal 291 364 5.1E-9 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 PRINTS PR00473 Galactokinase signature 272 286 7.5E-21 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 PRINTS PR00473 Galactokinase signature 97 108 7.5E-21 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 PRINTS PR00473 Galactokinase signature 32 50 7.5E-21 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 PRINTS PR00473 Galactokinase signature 117 135 7.5E-21 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 PRINTS PR00959 Mevalonate kinase family signature 335 352 3.9E-38 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 PRINTS PR00959 Mevalonate kinase family signature 30 54 3.9E-38 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 PRINTS PR00959 Mevalonate kinase family signature 124 146 3.9E-38 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 PRINTS PR00959 Mevalonate kinase family signature 167 186 3.9E-38 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 Pfam PF10509 Galactokinase galactose-binding signature 15 63 3.4E-17 T 06-07-2017 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 Gene3D G3DSA:3.30.230.10 13 215 4.7E-68 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 126 137 - T 06-07-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 SUPERFAMILY SSF54211 12 207 1.52E-56 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 SUPERFAMILY SSF55060 212 388 2.88E-44 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 TIGRFAM TIGR00131 gal_kin: galactokinase 14 370 4.2E-77 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 Gene3D G3DSA:3.30.70.890 216 387 9.9E-49 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain SMD11_RS20125 5ae73b78af73695da0a144a9054c7e02 390 Pfam PF00288 GHMP kinases N terminal domain 119 184 7.3E-14 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 SMD11_RS10650 8f2b87882ba12ecea40b1ee89d3aec00 647 Gene3D G3DSA:1.10.3810.10 89 265 1.7E-60 T 06-07-2017 SMD11_RS10650 8f2b87882ba12ecea40b1ee89d3aec00 647 SUPERFAMILY SSF56601 247 267 2.21E-52 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS10650 8f2b87882ba12ecea40b1ee89d3aec00 647 SUPERFAMILY SSF56601 297 645 2.21E-52 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS10650 8f2b87882ba12ecea40b1ee89d3aec00 647 Gene3D G3DSA:3.40.710.10 266 645 5.7E-64 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS10650 8f2b87882ba12ecea40b1ee89d3aec00 647 SUPERFAMILY SSF53955 78 285 1.1E-61 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS10650 8f2b87882ba12ecea40b1ee89d3aec00 647 Pfam PF00912 Transglycosylase 92 262 1.6E-54 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 SMD11_RS10650 8f2b87882ba12ecea40b1ee89d3aec00 647 Pfam PF00905 Penicillin binding protein transpeptidase domain 367 599 5.6E-18 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD11_RS03885 556c15d39d1d49917ecb1c57f2d0a672 232 Pfam PF00072 Response regulator receiver domain 4 112 6.2E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS03885 556c15d39d1d49917ecb1c57f2d0a672 232 SUPERFAMILY SSF52172 2 120 1.57E-41 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS03885 556c15d39d1d49917ecb1c57f2d0a672 232 Gene3D G3DSA:1.10.10.10 131 230 2.4E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03885 556c15d39d1d49917ecb1c57f2d0a672 232 Gene3D G3DSA:3.40.50.2300 1 119 1.1E-39 T 06-07-2017 SMD11_RS03885 556c15d39d1d49917ecb1c57f2d0a672 232 SUPERFAMILY SSF46894 130 229 7.65E-27 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS03885 556c15d39d1d49917ecb1c57f2d0a672 232 SMART SM00448 2 112 3.2E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS03885 556c15d39d1d49917ecb1c57f2d0a672 232 SMART SM00862 153 229 5.4E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS03885 556c15d39d1d49917ecb1c57f2d0a672 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 229 3.8E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS28705 c834fcab8f5d28e55d72a1541d1bdf5f 216 Pfam PF00072 Response regulator receiver domain 5 117 2.2E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS28705 c834fcab8f5d28e55d72a1541d1bdf5f 216 SMART SM00421 150 207 2.6E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28705 c834fcab8f5d28e55d72a1541d1bdf5f 216 SUPERFAMILY SSF46894 141 213 2.35E-19 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS28705 c834fcab8f5d28e55d72a1541d1bdf5f 216 Gene3D G3DSA:3.40.50.2300 2 119 1.4E-34 T 06-07-2017 SMD11_RS28705 c834fcab8f5d28e55d72a1541d1bdf5f 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 206 6.6E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28705 c834fcab8f5d28e55d72a1541d1bdf5f 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28705 c834fcab8f5d28e55d72a1541d1bdf5f 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 8.4E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28705 c834fcab8f5d28e55d72a1541d1bdf5f 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 8.4E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28705 c834fcab8f5d28e55d72a1541d1bdf5f 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 8.4E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28705 c834fcab8f5d28e55d72a1541d1bdf5f 216 SUPERFAMILY SSF52172 3 165 8.54E-32 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS28705 c834fcab8f5d28e55d72a1541d1bdf5f 216 SMART SM00448 3 117 6.8E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS28705 c834fcab8f5d28e55d72a1541d1bdf5f 216 Gene3D G3DSA:1.10.10.10 120 214 2.4E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS09625 22cc737d655c1a6a7b32e9f189ad35e5 515 SUPERFAMILY SSF52540 42 358 1.86E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09625 22cc737d655c1a6a7b32e9f189ad35e5 515 Gene3D G3DSA:1.20.120.140 2 89 7.0E-35 T 06-07-2017 SMD11_RS09625 22cc737d655c1a6a7b32e9f189ad35e5 515 Gene3D G3DSA:3.40.50.300 95 299 2.4E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09625 22cc737d655c1a6a7b32e9f189ad35e5 515 SUPERFAMILY SSF47446 331 432 2.78E-33 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 SMD11_RS09625 22cc737d655c1a6a7b32e9f189ad35e5 515 SMART SM00382 99 303 2.1E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS09625 22cc737d655c1a6a7b32e9f189ad35e5 515 SMART SM00962 100 298 2.0E-106 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD11_RS09625 22cc737d655c1a6a7b32e9f189ad35e5 515 SMART SM00963 1 86 5.0E-34 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD11_RS09625 22cc737d655c1a6a7b32e9f189ad35e5 515 Pfam PF00448 SRP54-type protein, GTPase domain 100 298 7.1E-69 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD11_RS09625 22cc737d655c1a6a7b32e9f189ad35e5 515 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 430 1.2E-172 T 06-07-2017 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 SMD11_RS09625 22cc737d655c1a6a7b32e9f189ad35e5 515 Gene3D G3DSA:1.10.260.30 331 433 3.3E-37 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 SMD11_RS09625 22cc737d655c1a6a7b32e9f189ad35e5 515 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 2.0E-21 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SMD11_RS09625 22cc737d655c1a6a7b32e9f189ad35e5 515 Pfam PF02978 Signal peptide binding domain 331 429 1.2E-30 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 SMD11_RS09625 22cc737d655c1a6a7b32e9f189ad35e5 515 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 448 33.286 T 06-07-2017 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 SMD11_RS30965 6d5f73efca83acf9daaef082f529cff2 492 Pfam PF02875 Mur ligase family, glutamate ligase domain 336 421 1.5E-22 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS30965 6d5f73efca83acf9daaef082f529cff2 492 Gene3D G3DSA:3.40.1390.10 13 103 4.9E-12 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMD11_RS30965 6d5f73efca83acf9daaef082f529cff2 492 Pfam PF08245 Mur ligase middle domain 114 316 7.6E-47 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS30965 6d5f73efca83acf9daaef082f529cff2 492 SUPERFAMILY SSF53623 105 335 5.23E-62 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS30965 6d5f73efca83acf9daaef082f529cff2 492 Gene3D G3DSA:3.40.1190.10 107 339 6.8E-73 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS30965 6d5f73efca83acf9daaef082f529cff2 492 Gene3D G3DSA:3.90.190.20 340 482 2.9E-50 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS30965 6d5f73efca83acf9daaef082f529cff2 492 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 112 136 - T 06-07-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 SMD11_RS30965 6d5f73efca83acf9daaef082f529cff2 492 SUPERFAMILY SSF53244 336 488 6.41E-48 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS30965 6d5f73efca83acf9daaef082f529cff2 492 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 25 488 3.9E-132 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 SMD11_RS30965 6d5f73efca83acf9daaef082f529cff2 492 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 489 31.364 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 SMD11_RS30965 6d5f73efca83acf9daaef082f529cff2 492 SUPERFAMILY SSF63418 20 105 9.94E-13 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMD11_RS14335 89d64d5177ee2671b32cce4b7b2f50d5 283 SMART SM00530 17 72 4.4E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS14335 89d64d5177ee2671b32cce4b7b2f50d5 283 Pfam PF13560 Helix-turn-helix domain 13 75 4.2E-12 T 06-07-2017 SMD11_RS14335 89d64d5177ee2671b32cce4b7b2f50d5 283 Gene3D G3DSA:1.10.260.40 8 73 1.6E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS14335 89d64d5177ee2671b32cce4b7b2f50d5 283 SUPERFAMILY SSF47413 10 74 2.95E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS22305 0e687eee8cc0c9e88e33f4b27935bdba 219 PRINTS PR00127 Clp protease catalytic subunit P signature 105 122 6.0E-49 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS22305 0e687eee8cc0c9e88e33f4b27935bdba 219 PRINTS PR00127 Clp protease catalytic subunit P signature 126 145 6.0E-49 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS22305 0e687eee8cc0c9e88e33f4b27935bdba 219 PRINTS PR00127 Clp protease catalytic subunit P signature 35 50 6.0E-49 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS22305 0e687eee8cc0c9e88e33f4b27935bdba 219 PRINTS PR00127 Clp protease catalytic subunit P signature 183 202 6.0E-49 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS22305 0e687eee8cc0c9e88e33f4b27935bdba 219 PRINTS PR00127 Clp protease catalytic subunit P signature 74 94 6.0E-49 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS22305 0e687eee8cc0c9e88e33f4b27935bdba 219 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 18 208 40.42 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS22305 0e687eee8cc0c9e88e33f4b27935bdba 219 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 127 140 - T 06-07-2017 IPR033135 ClpP, histidine active site SMD11_RS22305 0e687eee8cc0c9e88e33f4b27935bdba 219 Gene3D G3DSA:3.90.226.10 35 207 1.6E-77 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS22305 0e687eee8cc0c9e88e33f4b27935bdba 219 SUPERFAMILY SSF52096 35 206 7.05E-68 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS22305 0e687eee8cc0c9e88e33f4b27935bdba 219 Pfam PF00574 Clp protease 35 207 2.7E-79 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SMD11_RS20940 09c7748fdad996effa562e7aeb9055dc 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 215 2.3E-87 T 06-07-2017 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 SMD11_RS20940 09c7748fdad996effa562e7aeb9055dc 229 SUPERFAMILY SSF52540 1 221 5.32E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20940 09c7748fdad996effa562e7aeb9055dc 229 Pfam PF00005 ABC transporter 19 166 2.4E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS20940 09c7748fdad996effa562e7aeb9055dc 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS20940 09c7748fdad996effa562e7aeb9055dc 229 Gene3D G3DSA:3.40.50.300 1 221 3.3E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20940 09c7748fdad996effa562e7aeb9055dc 229 SMART SM00382 28 215 1.3E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS15905 dc65e6bc10a70172c247fdad51743780 220 Gene3D G3DSA:3.40.30.10 20 178 3.1E-14 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS15905 dc65e6bc10a70172c247fdad51743780 220 Pfam PF01323 DSBA-like thioredoxin domain 23 178 3.2E-10 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMD11_RS15905 dc65e6bc10a70172c247fdad51743780 220 SUPERFAMILY SSF52833 23 180 8.31E-20 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS12135 2f8177119b9798e5578088a418e5347c 425 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 13 400 8.6E-120 T 06-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 SMD11_RS12135 2f8177119b9798e5578088a418e5347c 425 Pfam PF02601 Exonuclease VII, large subunit 318 398 1.4E-10 T 06-07-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 SMD11_RS12135 2f8177119b9798e5578088a418e5347c 425 Pfam PF02601 Exonuclease VII, large subunit 129 350 1.4E-60 T 06-07-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 SMD11_RS12135 2f8177119b9798e5578088a418e5347c 425 Pfam PF13742 OB-fold nucleic acid binding domain 13 105 1.5E-16 T 06-07-2017 IPR025824 OB-fold nucleic acid binding domain GO:0003676 SMD11_RS12135 2f8177119b9798e5578088a418e5347c 425 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 5 401 25.076 T 06-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 SMD11_RS12015 3bdfdd97b10715716ed6a416d70fbd0a 352 Pfam PF00005 ABC transporter 44 202 3.4E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS12015 3bdfdd97b10715716ed6a416d70fbd0a 352 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 254 318 2.4E-22 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS12015 3bdfdd97b10715716ed6a416d70fbd0a 352 ProSitePatterns PS00211 ABC transporters family signature. 175 189 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS12015 3bdfdd97b10715716ed6a416d70fbd0a 352 SUPERFAMILY SSF52540 53 324 2.61E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12015 3bdfdd97b10715716ed6a416d70fbd0a 352 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 252 331 1.1E-28 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS12015 3bdfdd97b10715716ed6a416d70fbd0a 352 SMART SM00382 52 252 1.6E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS12015 3bdfdd97b10715716ed6a416d70fbd0a 352 Gene3D G3DSA:3.40.50.300 22 276 7.1E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08670 6ccae86d08b736d02abbec3a1a1412fc 356 SUPERFAMILY SSF53850 49 297 3.15E-37 T 06-07-2017 SMD11_RS08670 6ccae86d08b736d02abbec3a1a1412fc 356 Pfam PF09084 NMT1/THI5 like 65 279 2.0E-24 T 06-07-2017 IPR015168 SsuA/THI5-like SMD11_RS08670 6ccae86d08b736d02abbec3a1a1412fc 356 Gene3D G3DSA:3.40.190.10 135 265 5.8E-17 T 06-07-2017 SMD11_RS13855 2cb37b168c69acd9774c2cc5ab41d3bc 549 SMART SM00487 177 352 2.5E-21 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS13855 2cb37b168c69acd9774c2cc5ab41d3bc 549 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 474 499 1.1E-34 T 06-07-2017 SMD11_RS13855 2cb37b168c69acd9774c2cc5ab41d3bc 549 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 290 310 1.1E-34 T 06-07-2017 SMD11_RS13855 2cb37b168c69acd9774c2cc5ab41d3bc 549 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 455 473 1.1E-34 T 06-07-2017 SMD11_RS13855 2cb37b168c69acd9774c2cc5ab41d3bc 549 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 355 377 1.1E-34 T 06-07-2017 SMD11_RS13855 2cb37b168c69acd9774c2cc5ab41d3bc 549 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 190 212 1.1E-34 T 06-07-2017 SMD11_RS13855 2cb37b168c69acd9774c2cc5ab41d3bc 549 Pfam PF04851 Type III restriction enzyme, res subunit 180 325 6.2E-12 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SMD11_RS13855 2cb37b168c69acd9774c2cc5ab41d3bc 549 SUPERFAMILY SSF52540 144 342 1.21E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13855 2cb37b168c69acd9774c2cc5ab41d3bc 549 Pfam PF13625 Helicase conserved C-terminal domain 5 133 2.4E-47 T 06-07-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 SMD11_RS13855 2cb37b168c69acd9774c2cc5ab41d3bc 549 Gene3D G3DSA:3.40.50.300 381 532 3.4E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13855 2cb37b168c69acd9774c2cc5ab41d3bc 549 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 352 540 8.3E-49 T 06-07-2017 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 SMD11_RS13855 2cb37b168c69acd9774c2cc5ab41d3bc 549 SUPERFAMILY SSF52540 289 359 5.8E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13855 2cb37b168c69acd9774c2cc5ab41d3bc 549 SUPERFAMILY SSF52540 392 510 5.8E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13855 2cb37b168c69acd9774c2cc5ab41d3bc 549 SMART SM00490 422 499 3.6E-12 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS13855 2cb37b168c69acd9774c2cc5ab41d3bc 549 Gene3D G3DSA:3.40.50.300 179 342 4.6E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 Gene3D G3DSA:3.30.390.30 355 474 1.4E-32 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 PIRSF PIRSF000350 1 479 9.1E-78 T 06-07-2017 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 SUPERFAMILY SSF51905 4 101 1.22E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 SUPERFAMILY SSF51905 141 350 1.22E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 193 218 4.2E-54 T 06-07-2017 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 292 4.2E-54 T 06-07-2017 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 357 378 4.2E-54 T 06-07-2017 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 166 4.2E-54 T 06-07-2017 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 4.2E-54 T 06-07-2017 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 321 328 4.2E-54 T 06-07-2017 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.2E-54 T 06-07-2017 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 437 4.2E-54 T 06-07-2017 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 444 464 4.2E-54 T 06-07-2017 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 363 468 1.1E-24 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 306 328 1.5E-33 T 06-07-2017 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 193 211 1.5E-33 T 06-07-2017 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 1.5E-33 T 06-07-2017 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.5E-33 T 06-07-2017 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 277 293 1.5E-33 T 06-07-2017 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 341 1.1E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 Gene3D G3DSA:3.50.50.60 158 349 2.9E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 Gene3D G3DSA:3.50.50.60 6 157 2.9E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12650 61d6bb2d667aacc6beda3c45ac11e781 485 SUPERFAMILY SSF55424 357 476 1.41E-29 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD11_RS21335 53ae87c8480c6710584e1d09541825c3 323 SMART SM00382 44 238 9.2E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS21335 53ae87c8480c6710584e1d09541825c3 323 Gene3D G3DSA:3.40.50.300 3 250 7.7E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21335 53ae87c8480c6710584e1d09541825c3 323 Pfam PF00005 ABC transporter 36 179 1.1E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS21335 53ae87c8480c6710584e1d09541825c3 323 SUPERFAMILY SSF52540 29 243 7.14E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15080 1ff5d906fb0e15710cd6a4acb8d3f15f 151 Gene3D G3DSA:1.10.3680.10 22 150 1.9E-22 T 06-07-2017 IPR029024 TerB-like SMD11_RS15080 1ff5d906fb0e15710cd6a4acb8d3f15f 151 SUPERFAMILY SSF158682 21 150 4.05E-23 T 06-07-2017 IPR029024 TerB-like SMD11_RS15080 1ff5d906fb0e15710cd6a4acb8d3f15f 151 Pfam PF05099 Tellurite resistance protein TerB 12 150 6.1E-32 T 06-07-2017 IPR007791 Co-chaperone DjlA, N-terminal SMD11_RS33805 1ef6f90416a752f203341a5693c24692 633 Pfam PF00733 Asparagine synthase 216 591 1.3E-35 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMD11_RS33805 1ef6f90416a752f203341a5693c24692 633 Gene3D G3DSA:3.40.50.620 198 365 1.1E-23 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS33805 1ef6f90416a752f203341a5693c24692 633 Gene3D G3DSA:3.40.50.620 467 591 1.1E-23 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS33805 1ef6f90416a752f203341a5693c24692 633 SUPERFAMILY SSF52402 197 380 9.63E-24 T 06-07-2017 SMD11_RS33805 1ef6f90416a752f203341a5693c24692 633 SUPERFAMILY SSF52402 478 591 9.63E-24 T 06-07-2017 SMD11_RS19715 39fdf28e51a8697e83d2f27a272c4b97 324 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 298 1.1E-95 T 06-07-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SMD11_RS19715 39fdf28e51a8697e83d2f27a272c4b97 324 SUPERFAMILY SSF53613 1 292 3.12E-60 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS19715 39fdf28e51a8697e83d2f27a272c4b97 324 Pfam PF00294 pfkB family carbohydrate kinase 22 290 5.0E-36 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB SMD11_RS19715 39fdf28e51a8697e83d2f27a272c4b97 324 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 299 7.5E-96 T 06-07-2017 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 SMD11_RS19715 39fdf28e51a8697e83d2f27a272c4b97 324 Gene3D G3DSA:3.40.1190.20 32 294 2.0E-67 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS19715 39fdf28e51a8697e83d2f27a272c4b97 324 PIRSF PIRSF000535 1 302 5.4E-71 T 06-07-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SMD11_RS15890 79ab75578d2f2391e3d64ba4b09f7b52 351 Gene3D G3DSA:3.40.50.1110 74 154 1.2E-9 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS15890 79ab75578d2f2391e3d64ba4b09f7b52 351 Gene3D G3DSA:3.40.50.1110 219 348 1.2E-9 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS15890 79ab75578d2f2391e3d64ba4b09f7b52 351 SUPERFAMILY SSF52266 282 348 2.8E-14 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS15890 79ab75578d2f2391e3d64ba4b09f7b52 351 SUPERFAMILY SSF52266 218 252 2.8E-14 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS15890 79ab75578d2f2391e3d64ba4b09f7b52 351 SUPERFAMILY SSF52266 74 148 2.8E-14 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS12815 a783b834094466b78513121bc4a67584 131 SUPERFAMILY SSF53927 6 129 9.03E-41 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 SMD11_RS12815 a783b834094466b78513121bc4a67584 131 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 10 101 2.8E-11 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 SMD11_RS12815 a783b834094466b78513121bc4a67584 131 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 9 128 2.3E-34 T 06-07-2017 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-73614 SMD11_RS12815 a783b834094466b78513121bc4a67584 131 Gene3D G3DSA:3.40.140.10 6 130 9.4E-44 T 06-07-2017 SMD11_RS09700 15e182190b83f8f7dc64a8f113558b2a 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 55 18.881 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09700 15e182190b83f8f7dc64a8f113558b2a 57 SUPERFAMILY SSF57829 2 57 2.26E-21 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 SMD11_RS09700 15e182190b83f8f7dc64a8f113558b2a 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 1.8E-26 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09700 15e182190b83f8f7dc64a8f113558b2a 57 Pfam PF01783 Ribosomal L32p protein family 2 56 1.6E-26 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16805 a1f485b3e25691b13b07c06f4725c04e 222 SUPERFAMILY SSF46785 8 183 7.83E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16805 a1f485b3e25691b13b07c06f4725c04e 222 Pfam PF03551 Transcriptional regulator PadR-like family 12 94 5.3E-14 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal SMD11_RS16805 a1f485b3e25691b13b07c06f4725c04e 222 Gene3D G3DSA:1.10.10.10 4 99 3.0E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS22100 042647f427d054a42d5e87f5eccab1c6 427 Gene3D G3DSA:3.40.50.720 1 157 1.9E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS22100 042647f427d054a42d5e87f5eccab1c6 427 SUPERFAMILY SSF56327 165 424 1.3E-60 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMD11_RS22100 042647f427d054a42d5e87f5eccab1c6 427 Pfam PF02056 Family 4 glycosyl hydrolase 2 179 4.6E-45 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD11_RS22100 042647f427d054a42d5e87f5eccab1c6 427 Gene3D G3DSA:3.90.110.10 162 424 4.5E-85 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMD11_RS22100 042647f427d054a42d5e87f5eccab1c6 427 PRINTS PR00732 Glycosyl hydrolase family 4 signature 135 152 3.4E-34 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD11_RS22100 042647f427d054a42d5e87f5eccab1c6 427 PRINTS PR00732 Glycosyl hydrolase family 4 signature 185 197 3.4E-34 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD11_RS22100 042647f427d054a42d5e87f5eccab1c6 427 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 3.4E-34 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD11_RS22100 042647f427d054a42d5e87f5eccab1c6 427 PRINTS PR00732 Glycosyl hydrolase family 4 signature 106 126 3.4E-34 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD11_RS22100 042647f427d054a42d5e87f5eccab1c6 427 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 3.4E-34 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD11_RS22100 042647f427d054a42d5e87f5eccab1c6 427 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 3.4E-34 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD11_RS22100 042647f427d054a42d5e87f5eccab1c6 427 SUPERFAMILY SSF51735 1 156 1.36E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS22100 042647f427d054a42d5e87f5eccab1c6 427 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 190 403 1.1E-39 T 06-07-2017 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 SMD11_RS15340 ebf8e4cf770406b317b75474698a9053 361 SUPERFAMILY SSF52540 123 352 1.2E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15340 ebf8e4cf770406b317b75474698a9053 361 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 3 351 2.8E-96 T 06-07-2017 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like SMD11_RS15340 ebf8e4cf770406b317b75474698a9053 361 Gene3D G3DSA:3.40.50.300 122 352 1.9E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15340 ebf8e4cf770406b317b75474698a9053 361 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 128 285 1.7E-9 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain SMD11_RS01270 e56210e521b1408ebd30097571e63389 335 Pfam PF01497 Periplasmic binding protein 72 306 7.2E-34 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD11_RS01270 e56210e521b1408ebd30097571e63389 335 Gene3D G3DSA:3.40.50.1980 51 169 1.2E-37 T 06-07-2017 SMD11_RS01270 e56210e521b1408ebd30097571e63389 335 Gene3D G3DSA:3.40.50.1980 170 328 7.3E-36 T 06-07-2017 SMD11_RS01270 e56210e521b1408ebd30097571e63389 335 SUPERFAMILY SSF53807 53 325 2.08E-66 T 06-07-2017 SMD11_RS30690 d3d00baa9ae2f2c96de6fdd797c94a39 199 Gene3D G3DSA:3.40.50.720 1 198 2.0E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30690 d3d00baa9ae2f2c96de6fdd797c94a39 199 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 145 1.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30690 d3d00baa9ae2f2c96de6fdd797c94a39 199 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30690 d3d00baa9ae2f2c96de6fdd797c94a39 199 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 55 66 1.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30690 d3d00baa9ae2f2c96de6fdd797c94a39 199 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 162 1.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30690 d3d00baa9ae2f2c96de6fdd797c94a39 199 SUPERFAMILY SSF51735 1 198 1.44E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30690 d3d00baa9ae2f2c96de6fdd797c94a39 199 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 158 4.4E-13 T 06-07-2017 SMD11_RS26405 157957df5c56373d50f5dd5e044cfb7e 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 58 1.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS26405 157957df5c56373d50f5dd5e044cfb7e 201 Gene3D G3DSA:1.10.357.10 1 197 3.4E-44 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS26405 157957df5c56373d50f5dd5e044cfb7e 201 Pfam PF13977 Bacterial transcriptional repressor 88 197 1.6E-16 T 06-07-2017 SMD11_RS26405 157957df5c56373d50f5dd5e044cfb7e 201 SUPERFAMILY SSF46689 1 69 2.21E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS26405 157957df5c56373d50f5dd5e044cfb7e 201 SUPERFAMILY SSF48498 83 196 3.34E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS22385 c45f2151b506e5e0c32e5bd08fb7457f 521 Pfam PF08245 Mur ligase middle domain 124 351 1.4E-14 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS22385 c45f2151b506e5e0c32e5bd08fb7457f 521 SUPERFAMILY SSF53244 381 519 4.03E-26 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS22385 c45f2151b506e5e0c32e5bd08fb7457f 521 Pfam PF02875 Mur ligase family, glutamate ligase domain 380 457 3.0E-11 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS22385 c45f2151b506e5e0c32e5bd08fb7457f 521 Gene3D G3DSA:3.40.1190.10 98 378 2.2E-94 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS22385 c45f2151b506e5e0c32e5bd08fb7457f 521 TIGRFAM TIGR01499 folC: bifunctional protein FolC 103 515 7.7E-99 T 06-07-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 SMD11_RS22385 c45f2151b506e5e0c32e5bd08fb7457f 521 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 220 235 - T 06-07-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 SMD11_RS22385 c45f2151b506e5e0c32e5bd08fb7457f 521 Gene3D G3DSA:3.90.190.20 381 520 1.9E-37 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS22385 c45f2151b506e5e0c32e5bd08fb7457f 521 SUPERFAMILY SSF53623 82 376 1.12E-88 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS30030 0208723c223a1bbef54c32ded8036a25 192 Gene3D G3DSA:3.40.630.30 3 181 1.2E-35 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS30030 0208723c223a1bbef54c32ded8036a25 192 SUPERFAMILY SSF55729 2 177 3.73E-33 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS30030 0208723c223a1bbef54c32ded8036a25 192 Pfam PF13302 Acetyltransferase (GNAT) domain 10 136 2.3E-17 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS21445 85a2a881bd643f35ec01beb8b4f135cc 331 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 4.1E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS21445 85a2a881bd643f35ec01beb8b4f135cc 331 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 4.1E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS21445 85a2a881bd643f35ec01beb8b4f135cc 331 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 4.1E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS21445 85a2a881bd643f35ec01beb8b4f135cc 331 SUPERFAMILY SSF46955 1 111 9.89E-22 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS21445 85a2a881bd643f35ec01beb8b4f135cc 331 Gene3D G3DSA:3.40.30.10 169 312 1.8E-16 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS21445 85a2a881bd643f35ec01beb8b4f135cc 331 SUPERFAMILY SSF52833 168 328 1.36E-22 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS21445 85a2a881bd643f35ec01beb8b4f135cc 331 Gene3D G3DSA:1.10.1660.10 1 111 4.6E-26 T 06-07-2017 SMD11_RS21445 85a2a881bd643f35ec01beb8b4f135cc 331 SMART SM00422 1 69 1.5E-20 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS21445 85a2a881bd643f35ec01beb8b4f135cc 331 Pfam PF08534 Redoxin 171 318 4.5E-17 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 SMD11_RS21445 85a2a881bd643f35ec01beb8b4f135cc 331 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS21445 85a2a881bd643f35ec01beb8b4f135cc 331 Pfam PF00376 MerR family regulatory protein 2 38 7.0E-14 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS23355 4411ff66efd84a31aeb168160a8220da 222 Pfam PF07510 Protein of unknown function (DUF1524) 106 217 4.7E-9 T 06-07-2017 IPR011089 Domain of unknown function DUF1524 SMD11_RS24700 98b96833aaefdf56b41b78e0550452c5 135 Pfam PF01042 Endoribonuclease L-PSP 21 128 1.1E-17 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family SMD11_RS24700 98b96833aaefdf56b41b78e0550452c5 135 Gene3D G3DSA:3.30.1330.40 8 131 2.0E-34 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD11_RS24700 98b96833aaefdf56b41b78e0550452c5 135 SUPERFAMILY SSF55298 8 130 5.81E-27 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD11_RS03175 fefc222380956b85ba39fbe102f5e69c 229 Pfam PF00072 Response regulator receiver domain 12 125 3.9E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS03175 fefc222380956b85ba39fbe102f5e69c 229 SMART SM00421 160 217 1.1E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS03175 fefc222380956b85ba39fbe102f5e69c 229 Gene3D G3DSA:1.10.10.10 134 224 2.6E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03175 fefc222380956b85ba39fbe102f5e69c 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 217 3.0E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS03175 fefc222380956b85ba39fbe102f5e69c 229 SUPERFAMILY SSF46894 155 223 5.1E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS03175 fefc222380956b85ba39fbe102f5e69c 229 SUPERFAMILY SSF52172 7 135 2.56E-34 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS03175 fefc222380956b85ba39fbe102f5e69c 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 1.2E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS03175 fefc222380956b85ba39fbe102f5e69c 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 1.2E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS03175 fefc222380956b85ba39fbe102f5e69c 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 1.2E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS03175 fefc222380956b85ba39fbe102f5e69c 229 SMART SM00448 10 125 3.0E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS03175 fefc222380956b85ba39fbe102f5e69c 229 Gene3D G3DSA:3.40.50.2300 7 133 8.0E-39 T 06-07-2017 SMD11_RS19735 52524c93ea90876d0c2de1da14ed3a4a 365 SUPERFAMILY SSF53335 68 190 1.93E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS19735 52524c93ea90876d0c2de1da14ed3a4a 365 Gene3D G3DSA:3.40.50.150 1 219 1.0E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS19735 52524c93ea90876d0c2de1da14ed3a4a 365 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 62 182 2.4E-24 T 06-07-2017 SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 Pfam PF03527 RHS protein 1357 1387 8.2E-7 T 06-07-2017 IPR001826 RHS protein SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 Pfam PF05593 RHS Repeat 940 974 1.8E-9 T 06-07-2017 IPR031325 RHS repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 Pfam PF05593 RHS Repeat 748 785 4.5E-7 T 06-07-2017 IPR031325 RHS repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 Pfam PF05593 RHS Repeat 728 764 1.3E-8 T 06-07-2017 IPR031325 RHS repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 Pfam PF05593 RHS Repeat 833 869 3.1E-9 T 06-07-2017 IPR031325 RHS repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 Pfam PF05593 RHS Repeat 1255 1284 1.5E-7 T 06-07-2017 IPR031325 RHS repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 Pfam PF05593 RHS Repeat 1000 1033 6.8E-7 T 06-07-2017 IPR031325 RHS repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 Pfam PF05593 RHS Repeat 790 826 1.3E-7 T 06-07-2017 IPR031325 RHS repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1255 1287 2.0E-7 T 06-07-2017 IPR006530 YD repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 769 808 2.5E-6 T 06-07-2017 IPR006530 YD repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 811 851 8.8E-7 T 06-07-2017 IPR006530 YD repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 979 1018 6.2E-5 T 06-07-2017 IPR006530 YD repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 731 764 2.2E-7 T 06-07-2017 IPR006530 YD repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 937 977 3.4E-10 T 06-07-2017 IPR006530 YD repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 877 913 5.5E-7 T 06-07-2017 IPR006530 YD repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1250 1269 0.002 T 06-07-2017 IPR006530 YD repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1170 1205 3.5E-4 T 06-07-2017 IPR006530 YD repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 854 893 8.6E-4 T 06-07-2017 IPR006530 YD repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1060 1092 4.4E-4 T 06-07-2017 IPR006530 YD repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 895 930 3.2E-4 T 06-07-2017 IPR006530 YD repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 618 652 6.3E-6 T 06-07-2017 IPR006530 YD repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 832 873 2.1E-7 T 06-07-2017 IPR006530 YD repeat SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 SUPERFAMILY SSF69304 748 985 9.29E-7 T 06-07-2017 SMD11_RS12930 7a8af3f2b2c4faf968395606da66b00c 1610 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1382 1456 6.4E-22 T 06-07-2017 IPR022385 Rhs repeat-associated core GO:0097264 SMD11_RS17775 410f3a8e3c2c9a412f3eeb47bb65a72c 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 2.9E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17775 410f3a8e3c2c9a412f3eeb47bb65a72c 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 2.9E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17775 410f3a8e3c2c9a412f3eeb47bb65a72c 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 2.9E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17775 410f3a8e3c2c9a412f3eeb47bb65a72c 219 SUPERFAMILY SSF46894 146 215 1.6E-22 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS17775 410f3a8e3c2c9a412f3eeb47bb65a72c 219 SUPERFAMILY SSF52172 2 132 1.85E-34 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS17775 410f3a8e3c2c9a412f3eeb47bb65a72c 219 Gene3D G3DSA:3.40.50.2300 1 125 7.6E-40 T 06-07-2017 SMD11_RS17775 410f3a8e3c2c9a412f3eeb47bb65a72c 219 SMART SM00421 152 209 3.5E-25 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17775 410f3a8e3c2c9a412f3eeb47bb65a72c 219 Gene3D G3DSA:1.10.10.10 126 216 4.1E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17775 410f3a8e3c2c9a412f3eeb47bb65a72c 219 Pfam PF00072 Response regulator receiver domain 5 114 1.6E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS17775 410f3a8e3c2c9a412f3eeb47bb65a72c 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 2.7E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17775 410f3a8e3c2c9a412f3eeb47bb65a72c 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17775 410f3a8e3c2c9a412f3eeb47bb65a72c 219 SMART SM00448 3 116 1.3E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS30715 c03f0095f93812faa06d3f8e65bbacf2 471 SUPERFAMILY SSF51126 30 396 2.16E-64 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor SMD11_RS30715 c03f0095f93812faa06d3f8e65bbacf2 471 Pfam PF14592 Chondroitinase B 31 298 4.4E-39 T 06-07-2017 SMD11_RS30715 c03f0095f93812faa06d3f8e65bbacf2 471 SMART SM00710 123 145 3900.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS30715 c03f0095f93812faa06d3f8e65bbacf2 471 SMART SM00710 47 69 4000.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS30715 c03f0095f93812faa06d3f8e65bbacf2 471 SMART SM00710 324 363 4200.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS30715 c03f0095f93812faa06d3f8e65bbacf2 471 SMART SM00710 260 281 100.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS30715 c03f0095f93812faa06d3f8e65bbacf2 471 SMART SM00710 179 207 6200.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS30715 c03f0095f93812faa06d3f8e65bbacf2 471 SMART SM00710 214 237 7700.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS30715 c03f0095f93812faa06d3f8e65bbacf2 471 SMART SM00710 148 170 620.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS30715 c03f0095f93812faa06d3f8e65bbacf2 471 SMART SM00710 238 259 9.5 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS30715 c03f0095f93812faa06d3f8e65bbacf2 471 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 238 271 4.0E-5 T 06-07-2017 IPR022441 Parallel beta-helix repeat-2 SMD11_RS30715 c03f0095f93812faa06d3f8e65bbacf2 471 Gene3D G3DSA:2.160.20.10 30 470 5.9E-79 T 06-07-2017 IPR012334 Pectin lyase fold SMD11_RS17550 ac41c79d93612291d1ec02006fa7cf26 469 SMART SM00530 9 65 8.1E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS17550 ac41c79d93612291d1ec02006fa7cf26 469 Pfam PF13560 Helix-turn-helix domain 6 64 3.4E-13 T 06-07-2017 SMD11_RS17550 ac41c79d93612291d1ec02006fa7cf26 469 SUPERFAMILY SSF47413 9 75 5.32E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS17550 ac41c79d93612291d1ec02006fa7cf26 469 Gene3D G3DSA:1.10.260.40 6 66 5.4E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS22450 f0156bac8365f41055166ad8679f13bb 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 72 1.0E-18 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS22450 f0156bac8365f41055166ad8679f13bb 85 Pfam PF01016 Ribosomal L27 protein 2 80 1.1E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS22450 f0156bac8365f41055166ad8679f13bb 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 06-07-2017 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS22450 f0156bac8365f41055166ad8679f13bb 85 Gene3D G3DSA:2.40.50.100 20 81 2.2E-28 T 06-07-2017 SMD11_RS22450 f0156bac8365f41055166ad8679f13bb 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 7.8E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS22450 f0156bac8365f41055166ad8679f13bb 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 26.813 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS22450 f0156bac8365f41055166ad8679f13bb 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 5.9E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS22450 f0156bac8365f41055166ad8679f13bb 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 5.9E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS22450 f0156bac8365f41055166ad8679f13bb 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 5.9E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS22450 f0156bac8365f41055166ad8679f13bb 85 SUPERFAMILY SSF110324 2 81 9.07E-31 T 06-07-2017 SMD11_RS31395 a562afc3b6db08de959a4a7a970790b7 301 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 12 293 1.1E-122 T 06-07-2017 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 SMD11_RS31395 a562afc3b6db08de959a4a7a970790b7 301 Gene3D G3DSA:3.20.20.60 10 290 4.6E-100 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS31395 a562afc3b6db08de959a4a7a970790b7 301 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 9 295 48.073 T 06-07-2017 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 SMD11_RS31395 a562afc3b6db08de959a4a7a970790b7 301 SUPERFAMILY SSF51621 6 294 1.35E-100 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS31395 a562afc3b6db08de959a4a7a970790b7 301 Pfam PF13714 Phosphoenolpyruvate phosphomutase 19 255 3.2E-52 T 06-07-2017 SMD11_RS31395 a562afc3b6db08de959a4a7a970790b7 301 ProSitePatterns PS00161 Isocitrate lyase signature. 124 129 - T 06-07-2017 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 SMD11_RS08000 dc6c44e92c1b0732864f6dfb92580471 309 SUPERFAMILY SSF53335 35 281 1.18E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS08000 dc6c44e92c1b0732864f6dfb92580471 309 Gene3D G3DSA:3.40.50.150 28 212 1.7E-23 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS08000 dc6c44e92c1b0732864f6dfb92580471 309 Pfam PF00398 Ribosomal RNA adenine dimethylase 27 278 4.8E-18 T 06-07-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm SMD11_RS08000 dc6c44e92c1b0732864f6dfb92580471 309 SMART SM00650 43 213 2.3E-38 T 06-07-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 SMD11_RS14840 ec65ec137b2a6a72d167636bbb977e19 265 Gene3D G3DSA:3.30.420.40 99 263 3.2E-51 T 06-07-2017 SMD11_RS14840 ec65ec137b2a6a72d167636bbb977e19 265 SUPERFAMILY SSF53067 128 261 2.33E-36 T 06-07-2017 SMD11_RS14840 ec65ec137b2a6a72d167636bbb977e19 265 SUPERFAMILY SSF53067 1 127 3.02E-34 T 06-07-2017 SMD11_RS14840 ec65ec137b2a6a72d167636bbb977e19 265 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 258 1.8E-77 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMD11_RS14840 ec65ec137b2a6a72d167636bbb977e19 265 Pfam PF03309 Type III pantothenate kinase 2 211 8.2E-71 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMD11_RS14840 ec65ec137b2a6a72d167636bbb977e19 265 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 262 35.936 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMD11_RS14840 ec65ec137b2a6a72d167636bbb977e19 265 Gene3D G3DSA:3.30.420.40 1 68 1.5E-4 T 06-07-2017 SMD11_RS01505 b0d882c598ecd4fac0b9a4c985b52a82 356 Pfam PF03704 Bacterial transcriptional activator domain 198 342 2.1E-39 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS01505 b0d882c598ecd4fac0b9a4c985b52a82 356 SUPERFAMILY SSF46894 9 75 1.5E-10 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS01505 b0d882c598ecd4fac0b9a4c985b52a82 356 Gene3D G3DSA:1.25.40.10 196 317 1.5E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS01505 b0d882c598ecd4fac0b9a4c985b52a82 356 Pfam PF00486 Transcriptional regulatory protein, C terminal 125 190 9.5E-12 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS01505 b0d882c598ecd4fac0b9a4c985b52a82 356 Gene3D G3DSA:1.10.10.10 111 191 1.3E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01505 b0d882c598ecd4fac0b9a4c985b52a82 356 SMART SM00862 116 191 5.7E-12 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS01505 b0d882c598ecd4fac0b9a4c985b52a82 356 Gene3D G3DSA:1.10.10.10 8 74 6.7E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01505 b0d882c598ecd4fac0b9a4c985b52a82 356 SUPERFAMILY SSF46894 103 191 2.27E-13 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS01505 b0d882c598ecd4fac0b9a4c985b52a82 356 SUPERFAMILY SSF48452 194 349 1.14E-32 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS01505 b0d882c598ecd4fac0b9a4c985b52a82 356 SMART SM00421 12 69 4.1E-4 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS01505 b0d882c598ecd4fac0b9a4c985b52a82 356 SMART SM01043 198 342 1.5E-43 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS05050 32b0a6830aa0a536ff194fe6c90de73f 762 Gene3D G3DSA:3.30.70.100 3 80 2.2E-21 T 06-07-2017 SMD11_RS05050 32b0a6830aa0a536ff194fe6c90de73f 762 SUPERFAMILY SSF54975 3 90 2.4E-22 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SMD11_RS05050 32b0a6830aa0a536ff194fe6c90de73f 762 ProSitePatterns PS00150 Acylphosphatase signature 1. 7 17 - T 06-07-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SMD11_RS05050 32b0a6830aa0a536ff194fe6c90de73f 762 Pfam PF00708 Acylphosphatase 4 88 1.5E-19 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SMD11_RS05050 32b0a6830aa0a536ff194fe6c90de73f 762 Gene3D G3DSA:3.90.870.10 198 374 1.7E-44 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain SMD11_RS05050 32b0a6830aa0a536ff194fe6c90de73f 762 Pfam PF01300 Telomere recombination 209 382 2.2E-49 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 SMD11_RS05050 32b0a6830aa0a536ff194fe6c90de73f 762 PIRSF PIRSF006256 1 762 5.6E-258 T 06-07-2017 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 SMD11_RS05050 32b0a6830aa0a536ff194fe6c90de73f 762 Pfam PF07503 HypF finger 161 193 4.0E-16 T 06-07-2017 IPR011125 Zinc finger, HypF-type GO:0008270 SMD11_RS05050 32b0a6830aa0a536ff194fe6c90de73f 762 Pfam PF07503 HypF finger 111 144 1.9E-15 T 06-07-2017 IPR011125 Zinc finger, HypF-type GO:0008270 SMD11_RS05050 32b0a6830aa0a536ff194fe6c90de73f 762 SUPERFAMILY SSF55821 178 387 8.55E-45 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain SMD11_RS05050 32b0a6830aa0a536ff194fe6c90de73f 762 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 5 755 6.0E-223 T 06-07-2017 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 SMD11_RS00935 f67b9f4d9ed459da812b83533ceb8780 296 Gene3D G3DSA:3.40.710.10 11 292 9.3E-60 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS00935 f67b9f4d9ed459da812b83533ceb8780 296 SUPERFAMILY SSF56601 178 288 2.51E-45 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS00935 f67b9f4d9ed459da812b83533ceb8780 296 SUPERFAMILY SSF56601 11 153 2.51E-45 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS00935 f67b9f4d9ed459da812b83533ceb8780 296 Pfam PF13354 Beta-lactamase enzyme family 31 262 1.4E-54 T 06-07-2017 SMD11_RS12810 832b456eadf94346d68e604c4e49f582 427 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 112 127 - T 06-07-2017 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS12810 832b456eadf94346d68e604c4e49f582 427 Pfam PF02885 Glycosyl transferase family, helical bundle domain 8 68 1.0E-17 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS12810 832b456eadf94346d68e604c4e49f582 427 SUPERFAMILY SSF54680 323 426 7.59E-26 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS12810 832b456eadf94346d68e604c4e49f582 427 SUPERFAMILY SSF52418 71 318 1.27E-80 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS12810 832b456eadf94346d68e604c4e49f582 427 Gene3D G3DSA:3.40.1030.10 72 319 7.1E-109 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS12810 832b456eadf94346d68e604c4e49f582 427 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 6 409 2.8E-167 T 06-07-2017 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS12810 832b456eadf94346d68e604c4e49f582 427 PIRSF PIRSF000478 2 425 1.7E-152 T 06-07-2017 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS12810 832b456eadf94346d68e604c4e49f582 427 Gene3D G3DSA:1.20.970.10 3 69 2.0E-27 T 06-07-2017 SMD11_RS12810 832b456eadf94346d68e604c4e49f582 427 Gene3D G3DSA:3.90.1170.30 320 412 8.2E-31 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS12810 832b456eadf94346d68e604c4e49f582 427 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 337 409 1.7E-23 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS12810 832b456eadf94346d68e604c4e49f582 427 Pfam PF00591 Glycosyl transferase family, a/b domain 81 289 1.1E-32 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS12810 832b456eadf94346d68e604c4e49f582 427 SMART SM00941 336 410 8.6E-33 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS12810 832b456eadf94346d68e604c4e49f582 427 SUPERFAMILY SSF47648 3 71 4.45E-20 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SMD11_RS21070 84730861aed64f573f71b3696b1f9d20 548 Gene3D G3DSA:1.10.287.1060 40 118 3.4E-5 T 06-07-2017 SMD11_RS21070 84730861aed64f573f71b3696b1f9d20 548 SUPERFAMILY SSF140453 41 118 5.62E-5 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like SMD11_RS11015 15b91ed8d32c859b03460d93f87ff863 328 SUPERFAMILY SSF46689 275 324 3.05E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS11015 15b91ed8d32c859b03460d93f87ff863 328 SUPERFAMILY SSF52317 17 204 2.8E-39 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS11015 15b91ed8d32c859b03460d93f87ff863 328 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 275 317 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD11_RS11015 15b91ed8d32c859b03460d93f87ff863 328 SUPERFAMILY SSF46689 223 272 1.61E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS11015 15b91ed8d32c859b03460d93f87ff863 328 SMART SM00342 238 321 5.8E-28 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS11015 15b91ed8d32c859b03460d93f87ff863 328 Pfam PF01965 DJ-1/PfpI family 95 183 3.0E-15 T 06-07-2017 IPR002818 DJ-1/PfpI SMD11_RS11015 15b91ed8d32c859b03460d93f87ff863 328 Pfam PF12833 Helix-turn-helix domain 244 322 3.1E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS11015 15b91ed8d32c859b03460d93f87ff863 328 Gene3D G3DSA:1.10.10.60 218 275 8.6E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS11015 15b91ed8d32c859b03460d93f87ff863 328 Gene3D G3DSA:1.10.10.60 276 323 6.3E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS11015 15b91ed8d32c859b03460d93f87ff863 328 Gene3D G3DSA:3.40.50.880 17 203 1.4E-43 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS19220 f42e82caafa31c4ebbf72ac0fc017b79 102 PRINTS PR00297 10kDa chaperonin signature 10 25 2.3E-30 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD11_RS19220 f42e82caafa31c4ebbf72ac0fc017b79 102 PRINTS PR00297 10kDa chaperonin signature 87 100 2.3E-30 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD11_RS19220 f42e82caafa31c4ebbf72ac0fc017b79 102 PRINTS PR00297 10kDa chaperonin signature 32 53 2.3E-30 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD11_RS19220 f42e82caafa31c4ebbf72ac0fc017b79 102 PRINTS PR00297 10kDa chaperonin signature 66 78 2.3E-30 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD11_RS19220 f42e82caafa31c4ebbf72ac0fc017b79 102 SUPERFAMILY SSF50129 9 101 9.42E-33 T 06-07-2017 IPR011032 GroES-like SMD11_RS19220 f42e82caafa31c4ebbf72ac0fc017b79 102 Gene3D G3DSA:2.30.33.40 10 101 2.7E-36 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD11_RS19220 f42e82caafa31c4ebbf72ac0fc017b79 102 SMART SM00883 9 100 2.8E-51 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD11_RS19220 f42e82caafa31c4ebbf72ac0fc017b79 102 ProSitePatterns PS00681 Chaperonins cpn10 signature. 10 34 - T 06-07-2017 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 SMD11_RS19220 f42e82caafa31c4ebbf72ac0fc017b79 102 Hamap MF_00580 10 kDa chaperonin [groS]. 9 101 25.358 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD11_RS19220 f42e82caafa31c4ebbf72ac0fc017b79 102 Pfam PF00166 Chaperonin 10 Kd subunit 10 100 9.6E-33 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD11_RS27775 f7108012a9b76f0e1e2adaa6b1cbe02e 411 Pfam PF00067 Cytochrome P450 220 370 3.0E-23 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27775 f7108012a9b76f0e1e2adaa6b1cbe02e 411 SUPERFAMILY SSF48264 5 401 1.96E-91 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27775 f7108012a9b76f0e1e2adaa6b1cbe02e 411 PRINTS PR00359 B-class P450 signature 350 361 5.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27775 f7108012a9b76f0e1e2adaa6b1cbe02e 411 PRINTS PR00359 B-class P450 signature 194 216 5.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27775 f7108012a9b76f0e1e2adaa6b1cbe02e 411 PRINTS PR00359 B-class P450 signature 292 319 5.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27775 f7108012a9b76f0e1e2adaa6b1cbe02e 411 PRINTS PR00359 B-class P450 signature 93 104 5.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27775 f7108012a9b76f0e1e2adaa6b1cbe02e 411 PRINTS PR00359 B-class P450 signature 274 285 5.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27775 f7108012a9b76f0e1e2adaa6b1cbe02e 411 PRINTS PR00359 B-class P450 signature 320 335 5.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27775 f7108012a9b76f0e1e2adaa6b1cbe02e 411 PRINTS PR00359 B-class P450 signature 341 350 5.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27775 f7108012a9b76f0e1e2adaa6b1cbe02e 411 PRINTS PR00359 B-class P450 signature 140 156 5.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27775 f7108012a9b76f0e1e2adaa6b1cbe02e 411 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS27775 f7108012a9b76f0e1e2adaa6b1cbe02e 411 Gene3D G3DSA:1.10.630.10 3 402 4.5E-119 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS13135 e9c6235b5c3f9b57044e66b2974b9504 483 Gene3D G3DSA:3.40.640.10 157 369 8.0E-45 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS13135 e9c6235b5c3f9b57044e66b2974b9504 483 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 70 86 1.3E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS13135 e9c6235b5c3f9b57044e66b2974b9504 483 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 70 1.3E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS13135 e9c6235b5c3f9b57044e66b2974b9504 483 Pfam PF00155 Aminotransferase class I and II 136 423 2.6E-17 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS13135 e9c6235b5c3f9b57044e66b2974b9504 483 Gene3D G3DSA:1.10.10.10 37 104 1.2E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13135 e9c6235b5c3f9b57044e66b2974b9504 483 SUPERFAMILY SSF46785 28 100 8.53E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13135 e9c6235b5c3f9b57044e66b2974b9504 483 SMART SM00345 37 96 2.8E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS13135 e9c6235b5c3f9b57044e66b2974b9504 483 SUPERFAMILY SSF53383 114 477 2.64E-73 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS13135 e9c6235b5c3f9b57044e66b2974b9504 483 Pfam PF00392 Bacterial regulatory proteins, gntR family 37 96 9.8E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 Gene3D G3DSA:1.25.40.10 872 1049 2.0E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 SMART SM01043 95 237 9.6E-43 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 76 1.7E-6 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 SUPERFAMILY SSF46894 10 88 3.68E-10 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 Gene3D G3DSA:1.25.40.10 105 220 1.4E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 Gene3D G3DSA:1.10.10.10 15 88 1.4E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 PRINTS PR00364 Disease resistance protein signature 359 374 2.9E-5 T 06-07-2017 SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 PRINTS PR00364 Disease resistance protein signature 448 462 2.9E-5 T 06-07-2017 SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 PRINTS PR00364 Disease resistance protein signature 541 555 2.9E-5 T 06-07-2017 SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 Gene3D G3DSA:3.40.50.300 338 380 3.5E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 SUPERFAMILY SSF52540 333 608 5.19E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 SUPERFAMILY SSF48452 91 257 6.07E-30 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 SUPERFAMILY SSF48452 914 1041 7.36E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 SMART SM00028 100 133 200.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 SMART SM00028 940 973 0.0031 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 Pfam PF03704 Bacterial transcriptional activator domain 95 237 1.7E-36 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS23780 5fd436e3ff52fba3525e9dd66d030fc1 1197 SMART SM00862 16 88 1.2E-9 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS07465 baeba691c5a4307d7f0ef4ab7ab7a8a2 425 SUPERFAMILY SSF53098 24 242 1.63E-49 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS07465 baeba691c5a4307d7f0ef4ab7ab7a8a2 425 SUPERFAMILY SSF47819 225 336 9.16E-26 T 06-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 SMD11_RS07465 baeba691c5a4307d7f0ef4ab7ab7a8a2 425 Gene3D G3DSA:3.30.420.10 42 212 2.8E-7 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS07465 baeba691c5a4307d7f0ef4ab7ab7a8a2 425 Pfam PF01612 3'-5' exonuclease 42 205 2.9E-34 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SMD11_RS07465 baeba691c5a4307d7f0ef4ab7ab7a8a2 425 Pfam PF00570 HRDC domain 247 313 1.6E-14 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 SMD11_RS07465 baeba691c5a4307d7f0ef4ab7ab7a8a2 425 SMART SM00341 244 324 8.9E-19 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 SMD11_RS07465 baeba691c5a4307d7f0ef4ab7ab7a8a2 425 SMART SM00474 39 205 1.2E-37 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SMD11_RS12400 5b1209162660fe9e83c7e756eb8045f3 403 Pfam PF00155 Aminotransferase class I and II 34 393 5.2E-52 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS12400 5b1209162660fe9e83c7e756eb8045f3 403 Gene3D G3DSA:3.40.640.10 51 277 6.3E-69 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS12400 5b1209162660fe9e83c7e756eb8045f3 403 SUPERFAMILY SSF53383 7 398 4.3E-97 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS12400 5b1209162660fe9e83c7e756eb8045f3 403 Gene3D G3DSA:3.90.1150.10 278 401 1.9E-41 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS13760 878913739a8648e5f1dd05f067716b04 145 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site SMD11_RS13760 878913739a8648e5f1dd05f067716b04 145 SMART SM00347 29 129 2.3E-20 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS13760 878913739a8648e5f1dd05f067716b04 145 SUPERFAMILY SSF46785 11 136 7.16E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13760 878913739a8648e5f1dd05f067716b04 145 Pfam PF12802 MarR family 36 93 5.4E-15 T 06-07-2017 SMD11_RS13760 878913739a8648e5f1dd05f067716b04 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.6E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS13760 878913739a8648e5f1dd05f067716b04 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 1.6E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS13760 878913739a8648e5f1dd05f067716b04 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 1.6E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS13760 878913739a8648e5f1dd05f067716b04 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.6E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS13760 878913739a8648e5f1dd05f067716b04 145 Gene3D G3DSA:1.10.10.10 7 136 2.7E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS18470 e65862f68c0f952177641d2cb77af628 348 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 318 334 1.4E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD11_RS18470 e65862f68c0f952177641d2cb77af628 348 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 303 318 1.4E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD11_RS18470 e65862f68c0f952177641d2cb77af628 348 Gene3D G3DSA:1.10.10.60 287 334 1.1E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS18470 e65862f68c0f952177641d2cb77af628 348 Pfam PF12833 Helix-turn-helix domain 258 334 6.3E-18 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS18470 e65862f68c0f952177641d2cb77af628 348 SUPERFAMILY SSF46689 287 334 1.52E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS18470 e65862f68c0f952177641d2cb77af628 348 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 22 204 2.2E-47 T 06-07-2017 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal SMD11_RS18470 e65862f68c0f952177641d2cb77af628 348 SMART SM00342 251 334 5.8E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS27455 927eaf159f238ad6184f3126a38f526e 267 SUPERFAMILY SSF56317 1 265 1.28E-69 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS27455 927eaf159f238ad6184f3126a38f526e 267 Gene3D G3DSA:3.60.110.10 2 266 1.5E-73 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS27455 927eaf159f238ad6184f3126a38f526e 267 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 145 165 - T 06-07-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site SMD11_RS27455 927eaf159f238ad6184f3126a38f526e 267 Pfam PF00795 Carbon-nitrogen hydrolase 5 248 9.5E-44 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS06740 ea6504b728d201d5ea060b5f2424bfb8 248 SMART SM00345 11 70 1.6E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS06740 ea6504b728d201d5ea060b5f2424bfb8 248 SUPERFAMILY SSF46785 3 73 3.4E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06740 ea6504b728d201d5ea060b5f2424bfb8 248 Pfam PF07702 UTRA domain 107 237 5.4E-19 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS06740 ea6504b728d201d5ea060b5f2424bfb8 248 Gene3D G3DSA:1.10.10.10 4 70 1.7E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06740 ea6504b728d201d5ea060b5f2424bfb8 248 SUPERFAMILY SSF64288 58 244 2.2E-28 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS06740 ea6504b728d201d5ea060b5f2424bfb8 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 2.9E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS06740 ea6504b728d201d5ea060b5f2424bfb8 248 SMART SM00866 96 239 1.8E-15 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS06740 ea6504b728d201d5ea060b5f2424bfb8 248 Gene3D G3DSA:3.40.1410.10 71 242 6.5E-48 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS13960 abb2828cb47faedfed15de40ae41d87d 317 Gene3D G3DSA:3.30.420.40 2 143 6.3E-34 T 06-07-2017 SMD11_RS13960 abb2828cb47faedfed15de40ae41d87d 317 SUPERFAMILY SSF53067 4 303 1.3E-54 T 06-07-2017 SMD11_RS13960 abb2828cb47faedfed15de40ae41d87d 317 Pfam PF00480 ROK family 5 300 1.2E-60 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS13960 abb2828cb47faedfed15de40ae41d87d 317 Gene3D G3DSA:3.30.420.40 144 285 2.8E-48 T 06-07-2017 SMD11_RS07775 5ab4f7630c7c1229a3a41563230b8817 136 Pfam PF00550 Phosphopantetheine attachment site 11 64 1.9E-7 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS07775 5ab4f7630c7c1229a3a41563230b8817 136 SUPERFAMILY SSF47336 6 66 6.02E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS07775 5ab4f7630c7c1229a3a41563230b8817 136 ProSitePatterns PS00012 Phosphopantetheine attachment site. 36 51 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS07775 5ab4f7630c7c1229a3a41563230b8817 136 Gene3D G3DSA:1.10.1200.10 7 65 1.1E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS27425 a39a6c9ca6c5fdf2360ddbf41398c393 228 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 212 2.3E-82 T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS27425 a39a6c9ca6c5fdf2360ddbf41398c393 228 SUPERFAMILY SSF51366 4 214 1.71E-63 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMD11_RS27425 a39a6c9ca6c5fdf2360ddbf41398c393 228 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 132 154 - T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS27425 a39a6c9ca6c5fdf2360ddbf41398c393 228 Gene3D G3DSA:3.20.20.70 3 218 1.7E-91 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS27425 a39a6c9ca6c5fdf2360ddbf41398c393 228 Pfam PF00834 Ribulose-phosphate 3 epimerase family 5 199 1.7E-78 T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS27425 a39a6c9ca6c5fdf2360ddbf41398c393 228 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 30 44 - T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS27425 a39a6c9ca6c5fdf2360ddbf41398c393 228 PIRSF PIRSF001461 1 224 3.2E-96 T 06-07-2017 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS14980 73bdbfcf5bccbd47b695abcbcc62b4d3 165 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 SMD11_RS14980 73bdbfcf5bccbd47b695abcbcc62b4d3 165 Pfam PF00719 Inorganic pyrophosphatase 5 157 2.4E-52 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 SMD11_RS14980 73bdbfcf5bccbd47b695abcbcc62b4d3 165 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 32.699 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 SMD11_RS14980 73bdbfcf5bccbd47b695abcbcc62b4d3 165 SUPERFAMILY SSF50324 3 156 4.71E-58 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 SMD11_RS14980 73bdbfcf5bccbd47b695abcbcc62b4d3 165 Gene3D G3DSA:3.90.80.10 2 158 1.6E-54 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 SMD11_RS29720 5fc055b119984d92366057b5bc4b9c5a 177 Pfam PF06114 Domain of unknown function (DUF955) 60 114 1.5E-4 T 06-07-2017 IPR010359 HTH domain, IrrE-type SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 Gene3D G3DSA:2.60.120.200 1063 1123 1.5E-4 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1615 1714 6.7E-8 T 06-07-2017 SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1147 1301 1.5E-21 T 06-07-2017 SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 308 453 2.9E-21 T 06-07-2017 SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 SUPERFAMILY SSF49899 1141 1323 5.6E-27 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 SUPERFAMILY SSF49899 296 482 6.86E-26 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 SUPERFAMILY SSF49899 1542 1601 3.87E-17 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 SUPERFAMILY SSF49899 1407 1503 3.87E-17 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 Gene3D G3DSA:2.80.10.50 680 790 6.1E-6 T 06-07-2017 SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 Gene3D G3DSA:2.60.120.200 1393 1505 3.7E-29 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 Gene3D G3DSA:2.60.120.200 1143 1307 2.4E-24 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 Gene3D G3DSA:2.60.120.200 1542 1602 3.7E-29 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 Gene3D G3DSA:2.60.120.200 1614 1716 2.6E-11 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 Gene3D G3DSA:2.60.120.200 292 455 1.5E-23 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 SMART SM00560 1422 1599 0.023 T 06-07-2017 IPR006558 LamG-like jellyroll fold SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 SMART SM00560 322 451 7.3E-4 T 06-07-2017 IPR006558 LamG-like jellyroll fold SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 SMART SM00560 1164 1298 0.0021 T 06-07-2017 IPR006558 LamG-like jellyroll fold SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 SUPERFAMILY SSF49899 1651 1736 1.29E-9 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain SMD11_RS02535 ac92615e10f494b88889d24938184de3 2422 SUPERFAMILY SSF50370 682 800 1.96E-11 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS16690 4c2d765c5210002e0933fa22efccac82 269 Pfam PF00440 Bacterial regulatory proteins, tetR family 44 87 3.6E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS16690 4c2d765c5210002e0933fa22efccac82 269 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 63 86 1.1E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS16690 4c2d765c5210002e0933fa22efccac82 269 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 56 1.1E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS16690 4c2d765c5210002e0933fa22efccac82 269 SUPERFAMILY SSF48498 115 205 1.04E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS16690 4c2d765c5210002e0933fa22efccac82 269 SUPERFAMILY SSF46689 33 109 2.49E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS16690 4c2d765c5210002e0933fa22efccac82 269 Gene3D G3DSA:1.10.357.10 32 213 5.0E-38 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS22755 03761b099a23dfb33005d6077e4c4390 445 Pfam PF02056 Family 4 glycosyl hydrolase 4 182 3.8E-39 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD11_RS22755 03761b099a23dfb33005d6077e4c4390 445 Gene3D G3DSA:3.90.110.10 167 436 1.2E-87 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMD11_RS22755 03761b099a23dfb33005d6077e4c4390 445 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 193 425 1.2E-42 T 06-07-2017 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 SMD11_RS22755 03761b099a23dfb33005d6077e4c4390 445 SUPERFAMILY SSF51735 1 166 1.4E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS22755 03761b099a23dfb33005d6077e4c4390 445 SUPERFAMILY SSF56327 167 435 1.55E-55 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMD11_RS22755 03761b099a23dfb33005d6077e4c4390 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 163 174 1.8E-37 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD11_RS22755 03761b099a23dfb33005d6077e4c4390 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 1.8E-37 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD11_RS22755 03761b099a23dfb33005d6077e4c4390 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 1.8E-37 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD11_RS22755 03761b099a23dfb33005d6077e4c4390 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 189 201 1.8E-37 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD11_RS22755 03761b099a23dfb33005d6077e4c4390 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 1.8E-37 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD11_RS22755 03761b099a23dfb33005d6077e4c4390 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 109 129 1.8E-37 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD11_RS22755 03761b099a23dfb33005d6077e4c4390 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 138 155 1.8E-37 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SMD11_RS22755 03761b099a23dfb33005d6077e4c4390 445 Gene3D G3DSA:3.40.50.720 1 166 1.3E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS22755 03761b099a23dfb33005d6077e4c4390 445 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 138 168 - T 06-07-2017 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 SMD11_RS26645 dfbc6fac4f7543db529ab237fdb88ea6 485 PIRSF PIRSF006060 16 482 3.7E-68 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS26645 dfbc6fac4f7543db529ab237fdb88ea6 485 Pfam PF13520 Amino acid permease 45 441 5.1E-41 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS26645 dfbc6fac4f7543db529ab237fdb88ea6 485 TIGRFAM TIGR00908 2A0305: ethanolamine permease 24 471 7.6E-143 T 06-07-2017 IPR004757 Ethanolamine permease SMD11_RS29555 ffe76d0fbfc327f258e912dfc27b0b2b 129 Pfam PF13411 MerR HTH family regulatory protein 2 67 3.1E-19 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS29555 ffe76d0fbfc327f258e912dfc27b0b2b 129 SMART SM00422 1 69 6.5E-20 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS29555 ffe76d0fbfc327f258e912dfc27b0b2b 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 7.1E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS29555 ffe76d0fbfc327f258e912dfc27b0b2b 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 7.1E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS29555 ffe76d0fbfc327f258e912dfc27b0b2b 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 7.1E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS29555 ffe76d0fbfc327f258e912dfc27b0b2b 129 SUPERFAMILY SSF46955 1 113 5.13E-25 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS29555 ffe76d0fbfc327f258e912dfc27b0b2b 129 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS29555 ffe76d0fbfc327f258e912dfc27b0b2b 129 Gene3D G3DSA:1.10.1660.10 1 115 1.8E-27 T 06-07-2017 SMD11_RS18945 f951162046f2d85e8ed139066305cd3f 186 Gene3D G3DSA:3.30.1440.10 8 184 5.5E-75 T 06-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18945 f951162046f2d85e8ed139066305cd3f 186 PIRSF PIRSF002161 3 186 2.1E-63 T 06-07-2017 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18945 f951162046f2d85e8ed139066305cd3f 186 SUPERFAMILY SSF55282 9 184 3.77E-75 T 06-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18945 f951162046f2d85e8ed139066305cd3f 186 Pfam PF00673 ribosomal L5P family C-terminus 90 183 5.6E-39 T 06-07-2017 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18945 f951162046f2d85e8ed139066305cd3f 186 ProSitePatterns PS00358 Ribosomal protein L5 signature. 63 79 - T 06-07-2017 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18945 f951162046f2d85e8ed139066305cd3f 186 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 7 185 43.547 T 06-07-2017 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18945 f951162046f2d85e8ed139066305cd3f 186 Pfam PF00281 Ribosomal protein L5 30 86 2.0E-28 T 06-07-2017 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS26445 51d57fcb0b7d1b30f1d20aaafbd65680 252 Gene3D G3DSA:3.40.190.10 6 84 2.4E-13 T 06-07-2017 SMD11_RS26445 51d57fcb0b7d1b30f1d20aaafbd65680 252 SUPERFAMILY SSF53850 6 178 4.19E-20 T 06-07-2017 SMD11_RS26445 51d57fcb0b7d1b30f1d20aaafbd65680 252 Gene3D G3DSA:3.40.190.10 114 149 2.4E-5 T 06-07-2017 SMD11_RS26445 51d57fcb0b7d1b30f1d20aaafbd65680 252 Pfam PF03466 LysR substrate binding domain 6 176 3.4E-22 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS31655 77dd50472990e344cf026a176335dcb8 298 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 126 140 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS31655 77dd50472990e344cf026a176335dcb8 298 Gene3D G3DSA:3.30.1490.20 96 154 4.3E-11 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS31655 77dd50472990e344cf026a176335dcb8 298 Pfam PF08443 RimK-like ATP-grasp domain 90 250 5.3E-8 T 06-07-2017 IPR013651 ATP-grasp fold, RimK-type SMD11_RS31655 77dd50472990e344cf026a176335dcb8 298 SUPERFAMILY SSF56059 91 249 4.18E-24 T 06-07-2017 SMD11_RS31655 77dd50472990e344cf026a176335dcb8 298 Gene3D G3DSA:3.40.50.20 18 95 6.1E-9 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS33375 d281103509d3cc2a12f17aa36c0cf020 532 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 284 334 3.2E-5 T 06-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SMD11_RS33375 d281103509d3cc2a12f17aa36c0cf020 532 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 16 266 8.1E-30 T 06-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SMD11_RS33375 d281103509d3cc2a12f17aa36c0cf020 532 Pfam PF00391 PEP-utilising enzyme, mobile domain 400 481 2.0E-23 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD11_RS33375 d281103509d3cc2a12f17aa36c0cf020 532 SUPERFAMILY SSF52009 367 488 1.57E-31 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD11_RS33375 d281103509d3cc2a12f17aa36c0cf020 532 Gene3D G3DSA:3.30.470.20 225 320 2.4E-24 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS33375 d281103509d3cc2a12f17aa36c0cf020 532 Gene3D G3DSA:1.10.189.10 325 380 3.8E-17 T 06-07-2017 SMD11_RS33375 d281103509d3cc2a12f17aa36c0cf020 532 Gene3D G3DSA:1.20.80.30 109 146 1.5E-5 T 06-07-2017 SMD11_RS33375 d281103509d3cc2a12f17aa36c0cf020 532 Gene3D G3DSA:3.50.30.10 381 484 1.2E-33 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SMD11_RS33375 d281103509d3cc2a12f17aa36c0cf020 532 SUPERFAMILY SSF56059 1 356 1.7E-99 T 06-07-2017 SMD11_RS33375 d281103509d3cc2a12f17aa36c0cf020 532 Gene3D G3DSA:3.30.1490.20 181 224 7.8E-43 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS33375 d281103509d3cc2a12f17aa36c0cf020 532 Gene3D G3DSA:3.30.1490.20 2 108 7.8E-43 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS24085 8e95fe7120110f7208d43d19e2734ea4 510 Gene3D G3DSA:3.40.630.10 186 504 4.8E-132 T 06-07-2017 SMD11_RS24085 8e95fe7120110f7208d43d19e2734ea4 510 PRINTS PR00481 Cytosol aminopeptidase signature 348 368 2.6E-50 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SMD11_RS24085 8e95fe7120110f7208d43d19e2734ea4 510 PRINTS PR00481 Cytosol aminopeptidase signature 376 391 2.6E-50 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SMD11_RS24085 8e95fe7120110f7208d43d19e2734ea4 510 PRINTS PR00481 Cytosol aminopeptidase signature 267 284 2.6E-50 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SMD11_RS24085 8e95fe7120110f7208d43d19e2734ea4 510 PRINTS PR00481 Cytosol aminopeptidase signature 289 310 2.6E-50 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SMD11_RS24085 8e95fe7120110f7208d43d19e2734ea4 510 PRINTS PR00481 Cytosol aminopeptidase signature 326 347 2.6E-50 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 SMD11_RS24085 8e95fe7120110f7208d43d19e2734ea4 510 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 20 140 9.5E-26 T 06-07-2017 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 SMD11_RS24085 8e95fe7120110f7208d43d19e2734ea4 510 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 352 359 - T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 SMD11_RS24085 8e95fe7120110f7208d43d19e2734ea4 510 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 506 34.21 T 06-07-2017 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 SMD11_RS24085 8e95fe7120110f7208d43d19e2734ea4 510 SUPERFAMILY SSF53187 186 503 1.13E-114 T 06-07-2017 SMD11_RS24085 8e95fe7120110f7208d43d19e2734ea4 510 SUPERFAMILY SSF52949 17 141 2.83E-24 T 06-07-2017 SMD11_RS24085 8e95fe7120110f7208d43d19e2734ea4 510 Gene3D G3DSA:3.40.220.10 16 185 3.2E-38 T 06-07-2017 SMD11_RS24085 8e95fe7120110f7208d43d19e2734ea4 510 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 192 497 3.9E-116 T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 SMD11_RS22135 6d0b28158ef95d3747ac315a4152a613 178 SMART SM00507 70 119 4.3E-14 T 06-07-2017 IPR003615 HNH nuclease SMD11_RS22135 6d0b28158ef95d3747ac315a4152a613 178 Pfam PF14279 HNH endonuclease 83 129 6.5E-13 T 06-07-2017 IPR029471 HNH endonuclease 5 SMD11_RS14910 1d465a1f9a05abcf395f311f4477297b 397 SUPERFAMILY SSF52540 1 239 3.36E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14910 1d465a1f9a05abcf395f311f4477297b 397 Pfam PF00005 ABC transporter 19 164 8.2E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS14910 1d465a1f9a05abcf395f311f4477297b 397 Gene3D G3DSA:3.40.50.300 1 237 2.6E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14910 1d465a1f9a05abcf395f311f4477297b 397 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 14 375 5.2E-102 T 06-07-2017 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 SMD11_RS14910 1d465a1f9a05abcf395f311f4477297b 397 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS14910 1d465a1f9a05abcf395f311f4477297b 397 SMART SM00382 27 214 2.6E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS14910 1d465a1f9a05abcf395f311f4477297b 397 Gene3D G3DSA:3.10.580.10 257 375 1.1E-12 T 06-07-2017 SMD11_RS14910 1d465a1f9a05abcf395f311f4477297b 397 SUPERFAMILY SSF54631 258 374 5.37E-13 T 06-07-2017 SMD11_RS10350 f4225378fdbf3afc20450e39d7fdc0e9 809 Gene3D G3DSA:2.60.40.10 56 243 1.5E-48 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS10350 f4225378fdbf3afc20450e39d7fdc0e9 809 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 124 791 3.7E-291 T 06-07-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 SMD11_RS10350 f4225378fdbf3afc20450e39d7fdc0e9 809 Pfam PF00128 Alpha amylase, catalytic domain 281 369 6.0E-6 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS10350 f4225378fdbf3afc20450e39d7fdc0e9 809 Gene3D G3DSA:2.60.40.1180 680 792 9.4E-24 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta SMD11_RS10350 f4225378fdbf3afc20450e39d7fdc0e9 809 SUPERFAMILY SSF51011 681 793 2.88E-18 T 06-07-2017 SMD11_RS10350 f4225378fdbf3afc20450e39d7fdc0e9 809 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 126 181 1.2E-7 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 SMD11_RS10350 f4225378fdbf3afc20450e39d7fdc0e9 809 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 61 97 1.5E-4 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 SMD11_RS10350 f4225378fdbf3afc20450e39d7fdc0e9 809 SUPERFAMILY SSF51445 590 667 9.27E-133 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS10350 f4225378fdbf3afc20450e39d7fdc0e9 809 SUPERFAMILY SSF51445 224 561 9.27E-133 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS10350 f4225378fdbf3afc20450e39d7fdc0e9 809 Gene3D G3DSA:3.20.20.80 244 668 9.2E-122 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS10350 f4225378fdbf3afc20450e39d7fdc0e9 809 SMART SM00642 249 660 1.7E-8 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS10350 f4225378fdbf3afc20450e39d7fdc0e9 809 SUPERFAMILY SSF81296 56 238 1.65E-37 T 06-07-2017 IPR014756 Immunoglobulin E-set SMD11_RS06340 aae249f24ce176b2a0e92967a7e0ea5c 560 Pfam PF01565 FAD binding domain 73 207 6.9E-19 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD11_RS06340 aae249f24ce176b2a0e92967a7e0ea5c 560 Gene3D G3DSA:3.30.465.10 131 244 3.8E-8 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS06340 aae249f24ce176b2a0e92967a7e0ea5c 560 SUPERFAMILY SSF56176 46 245 9.81E-36 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS06340 aae249f24ce176b2a0e92967a7e0ea5c 560 Gene3D G3DSA:3.30.43.10 69 129 3.8E-5 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS06340 aae249f24ce176b2a0e92967a7e0ea5c 560 Pfam PF08031 Berberine and berberine like 503 555 1.3E-17 T 06-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 SMD11_RS05250 f4323045ed6070384a286ae541a4a4a7 277 SUPERFAMILY SSF53955 41 276 1.77E-96 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS05250 f4323045ed6070384a286ae541a4a4a7 277 Gene3D G3DSA:1.20.141.10 151 276 3.7E-68 T 06-07-2017 SMD11_RS05250 f4323045ed6070384a286ae541a4a4a7 277 Pfam PF01374 Glycosyl hydrolase family 46 55 264 1.3E-102 T 06-07-2017 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 SMD11_RS05250 f4323045ed6070384a286ae541a4a4a7 277 Gene3D G3DSA:3.30.386.10 37 150 1.9E-58 T 06-07-2017 IPR023099 Glycoside hydrolase, family 46, N-terminal GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 SMD11_RS05250 f4323045ed6070384a286ae541a4a4a7 277 PIRSF PIRSF036551 1 277 9.7E-117 T 06-07-2017 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 SMD11_RS28440 aef4666ade0d760f1f4247d2f64fc151 388 SUPERFAMILY SSF52540 7 206 1.93E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28440 aef4666ade0d760f1f4247d2f64fc151 388 Gene3D G3DSA:2.40.30.10 203 284 5.1E-25 T 06-07-2017 SMD11_RS28440 aef4666ade0d760f1f4247d2f64fc151 388 Pfam PF00009 Elongation factor Tu GTP binding domain 10 189 2.9E-26 T 06-07-2017 SMD11_RS28440 aef4666ade0d760f1f4247d2f64fc151 388 Pfam PF03144 Elongation factor Tu domain 2 213 283 4.7E-14 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMD11_RS28440 aef4666ade0d760f1f4247d2f64fc151 388 SUPERFAMILY SSF50465 292 382 2.56E-20 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SMD11_RS28440 aef4666ade0d760f1f4247d2f64fc151 388 SUPERFAMILY SSF50447 191 287 1.89E-21 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS28440 aef4666ade0d760f1f4247d2f64fc151 388 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.6E-9 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS28440 aef4666ade0d760f1f4247d2f64fc151 388 PRINTS PR00315 GTP-binding elongation factor signature 83 94 1.6E-9 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS28440 aef4666ade0d760f1f4247d2f64fc151 388 PRINTS PR00315 GTP-binding elongation factor signature 67 77 1.6E-9 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS28440 aef4666ade0d760f1f4247d2f64fc151 388 PRINTS PR00315 GTP-binding elongation factor signature 120 129 1.6E-9 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS28440 aef4666ade0d760f1f4247d2f64fc151 388 Gene3D G3DSA:3.40.50.300 7 202 3.5E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28440 aef4666ade0d760f1f4247d2f64fc151 388 Gene3D G3DSA:2.40.30.10 290 379 1.2E-21 T 06-07-2017 SMD11_RS28440 aef4666ade0d760f1f4247d2f64fc151 388 Pfam PF03143 Elongation factor Tu C-terminal domain 292 379 1.7E-11 T 06-07-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal SMD11_RS23270 b2975398ee700df421a07bdf0745cefe 140 Pfam PF11253 Protein of unknown function (DUF3052) 15 139 5.3E-58 T 06-07-2017 IPR021412 Protein of unknown function DUF3052 SMD11_RS17800 49ae5ae5236a83d535a98bd859394b6d 451 Gene3D G3DSA:3.40.640.10 68 320 3.0E-80 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS17800 49ae5ae5236a83d535a98bd859394b6d 451 Gene3D G3DSA:3.90.1150.10 321 445 1.3E-34 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS17800 49ae5ae5236a83d535a98bd859394b6d 451 Pfam PF00202 Aminotransferase class-III 34 443 8.5E-100 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS17800 49ae5ae5236a83d535a98bd859394b6d 451 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 285 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS17800 49ae5ae5236a83d535a98bd859394b6d 451 SUPERFAMILY SSF53383 14 444 2.96E-120 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS09490 4e19cfd4e4593cc24e1ec5f1ed5f7d59 362 SUPERFAMILY SSF53850 38 361 1.18E-51 T 06-07-2017 SMD11_RS09490 4e19cfd4e4593cc24e1ec5f1ed5f7d59 362 Pfam PF13343 Bacterial extracellular solute-binding protein 89 325 3.2E-23 T 06-07-2017 SMD11_RS09490 4e19cfd4e4593cc24e1ec5f1ed5f7d59 362 Gene3D G3DSA:3.40.190.10 292 352 3.8E-25 T 06-07-2017 SMD11_RS09490 4e19cfd4e4593cc24e1ec5f1ed5f7d59 362 Gene3D G3DSA:3.40.190.10 7 135 3.8E-25 T 06-07-2017 SMD11_RS09490 4e19cfd4e4593cc24e1ec5f1ed5f7d59 362 Gene3D G3DSA:3.40.190.10 142 291 1.9E-20 T 06-07-2017 SMD11_RS09490 4e19cfd4e4593cc24e1ec5f1ed5f7d59 362 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 38 356 8.9E-69 T 06-07-2017 IPR005948 Thiamine ABC transporter periplasmic binding protein GO:0005215|GO:0006810|GO:0015888|GO:0030288|GO:0030975 SMD11_RS31530 f3225017a1590129d6bd13c53efbace8 476 Gene3D G3DSA:1.20.1250.20 32 200 1.5E-26 T 06-07-2017 SMD11_RS31530 f3225017a1590129d6bd13c53efbace8 476 Gene3D G3DSA:1.20.1250.20 286 473 5.0E-11 T 06-07-2017 SMD11_RS31530 f3225017a1590129d6bd13c53efbace8 476 Pfam PF07690 Major Facilitator Superfamily 34 427 1.9E-36 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS31530 f3225017a1590129d6bd13c53efbace8 476 SUPERFAMILY SSF103473 264 473 7.06E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS31530 f3225017a1590129d6bd13c53efbace8 476 SUPERFAMILY SSF103473 31 216 7.06E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS24250 2a051429d5b71ec01926146106eec7da 256 SUPERFAMILY SSF144091 10 227 1.44E-39 T 06-07-2017 SMD11_RS24250 2a051429d5b71ec01926146106eec7da 256 Gene3D G3DSA:1.20.1540.10 12 224 5.8E-40 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMD11_RS24250 2a051429d5b71ec01926146106eec7da 256 Pfam PF01694 Rhomboid family 74 227 5.3E-38 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMD11_RS28590 23e6fe794932da870e5aa9d217322a99 470 SUPERFAMILY SSF53720 26 466 9.82E-110 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS28590 23e6fe794932da870e5aa9d217322a99 470 Pfam PF00171 Aldehyde dehydrogenase family 27 464 4.6E-107 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS28590 23e6fe794932da870e5aa9d217322a99 470 Gene3D G3DSA:3.40.309.10 256 429 5.9E-35 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS28590 23e6fe794932da870e5aa9d217322a99 470 Gene3D G3DSA:3.40.605.10 26 255 2.0E-67 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS20910 83ed765a65d1c3e03c86536b8a347103 1138 SMART SM00382 812 1037 1.4E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS20910 83ed765a65d1c3e03c86536b8a347103 1138 SMART SM00240 129 180 1.4E-10 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS20910 83ed765a65d1c3e03c86536b8a347103 1138 SUPERFAMILY SSF52540 801 1018 9.43E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20910 83ed765a65d1c3e03c86536b8a347103 1138 Pfam PF01580 FtsK/SpoIIIE family 804 1012 2.0E-17 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMD11_RS20910 83ed765a65d1c3e03c86536b8a347103 1138 SUPERFAMILY SSF49879 102 212 1.11E-23 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 SMD11_RS20910 83ed765a65d1c3e03c86536b8a347103 1138 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 113 202 1.4E-13 T 06-07-2017 IPR032030 YscD, cytoplasmic domain SMD11_RS20910 83ed765a65d1c3e03c86536b8a347103 1138 Gene3D G3DSA:3.40.50.300 960 1018 4.7E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20910 83ed765a65d1c3e03c86536b8a347103 1138 Gene3D G3DSA:3.40.50.300 797 927 4.7E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20910 83ed765a65d1c3e03c86536b8a347103 1138 Gene3D G3DSA:2.60.200.20 105 208 6.2E-22 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS18045 44c488098d6bf64558d081cf344019e8 314 SUPERFAMILY SSF51430 11 312 6.81E-84 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS18045 44c488098d6bf64558d081cf344019e8 314 Gene3D G3DSA:3.20.20.100 11 312 1.3E-84 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS18045 44c488098d6bf64558d081cf344019e8 314 Pfam PF00248 Aldo/keto reductase family 15 312 1.4E-63 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS18045 44c488098d6bf64558d081cf344019e8 314 PRINTS PR00069 Aldo-keto reductase signature 109 127 2.2E-5 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD11_RS18045 44c488098d6bf64558d081cf344019e8 314 PRINTS PR00069 Aldo-keto reductase signature 140 157 2.2E-5 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD11_RS07840 27e93bc5eedf4db13af63c2fbc1d0c98 147 ProDom PD012709 ANTIBIOTIC DNA-BINDING DIRECT ANTIMICROBIAL SEQUENCING 3D-STRUCTURE PRECURSOR SIGNAL APOPROTEIN NEOCARZINOSTATIN 42 137 6.0E-7 T 06-07-2017 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 SMD11_RS07840 27e93bc5eedf4db13af63c2fbc1d0c98 147 SUPERFAMILY SSF49319 35 147 4.84E-21 T 06-07-2017 IPR027273 Neocarzinostatin-like SMD11_RS07840 27e93bc5eedf4db13af63c2fbc1d0c98 147 Gene3D G3DSA:2.60.40.230 32 146 2.2E-27 T 06-07-2017 IPR027273 Neocarzinostatin-like SMD11_RS07840 27e93bc5eedf4db13af63c2fbc1d0c98 147 Pfam PF00960 Neocarzinostatin family 36 146 8.2E-24 T 06-07-2017 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 SMD11_RS07840 27e93bc5eedf4db13af63c2fbc1d0c98 147 PRINTS PR01885 Macromomycin family signature 87 104 1.4E-13 T 06-07-2017 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 SMD11_RS07840 27e93bc5eedf4db13af63c2fbc1d0c98 147 PRINTS PR01885 Macromomycin family signature 56 71 1.4E-13 T 06-07-2017 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 SMD11_RS07840 27e93bc5eedf4db13af63c2fbc1d0c98 147 PRINTS PR01885 Macromomycin family signature 112 128 1.4E-13 T 06-07-2017 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 SMD11_RS07840 27e93bc5eedf4db13af63c2fbc1d0c98 147 PRINTS PR01885 Macromomycin family signature 33 52 1.4E-13 T 06-07-2017 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 SMD11_RS05455 e6e3c65fba93c3e0c4d2e1158e630da2 652 Gene3D G3DSA:2.60.120.260 373 479 2.5E-34 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS05455 e6e3c65fba93c3e0c4d2e1158e630da2 652 Gene3D G3DSA:2.60.120.260 526 607 2.5E-34 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS05455 e6e3c65fba93c3e0c4d2e1158e630da2 652 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 357 600 1.2E-39 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMD11_RS05455 e6e3c65fba93c3e0c4d2e1158e630da2 652 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 57 330 1.4E-58 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SMD11_RS05455 e6e3c65fba93c3e0c4d2e1158e630da2 652 SMART SM00939 345 615 1.8E-41 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMD11_RS05455 e6e3c65fba93c3e0c4d2e1158e630da2 652 SUPERFAMILY SSF49785 415 608 5.1E-32 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS05455 e6e3c65fba93c3e0c4d2e1158e630da2 652 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 62 231 5.1E-20 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 SMD11_RS05455 e6e3c65fba93c3e0c4d2e1158e630da2 652 Gene3D G3DSA:3.40.50.1820 38 225 3.4E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS05455 e6e3c65fba93c3e0c4d2e1158e630da2 652 Gene3D G3DSA:3.40.50.1820 285 372 3.4E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS05455 e6e3c65fba93c3e0c4d2e1158e630da2 652 SUPERFAMILY SSF53474 29 368 4.39E-69 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS26800 1cd88211e5645ecb79f1d843e8a4842e 342 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 06-07-2017 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS26800 1cd88211e5645ecb79f1d843e8a4842e 342 SMART SM00859 4 136 1.5E-41 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD11_RS26800 1cd88211e5645ecb79f1d843e8a4842e 342 Gene3D G3DSA:3.30.360.10 155 310 3.2E-58 T 06-07-2017 SMD11_RS26800 1cd88211e5645ecb79f1d843e8a4842e 342 SUPERFAMILY SSF51735 4 170 9.48E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS26800 1cd88211e5645ecb79f1d843e8a4842e 342 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 4 342 4.2E-117 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS26800 1cd88211e5645ecb79f1d843e8a4842e 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 313 1.4E-21 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS26800 1cd88211e5645ecb79f1d843e8a4842e 342 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 336 38.117 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS26800 1cd88211e5645ecb79f1d843e8a4842e 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 128 2.8E-24 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD11_RS26800 1cd88211e5645ecb79f1d843e8a4842e 342 SUPERFAMILY SSF55347 146 310 1.96E-48 T 06-07-2017 SMD11_RS26800 1cd88211e5645ecb79f1d843e8a4842e 342 Gene3D G3DSA:3.40.50.720 2 154 9.6E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS34240 ee0daefd56ded382ce53c8f46fbd30e9 681 SUPERFAMILY SSF56349 465 650 4.41E-14 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD11_RS34240 ee0daefd56ded382ce53c8f46fbd30e9 681 Gene3D G3DSA:1.10.443.10 466 652 1.8E-14 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS34240 ee0daefd56ded382ce53c8f46fbd30e9 681 Pfam PF00589 Phage integrase family 466 650 1.8E-7 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS12570 b430e9534948b2365832206e80bdb152 264 Gene3D G3DSA:1.10.12.10 205 264 2.8E-17 T 06-07-2017 IPR014748 Crontonase, C-terminal SMD11_RS12570 b430e9534948b2365832206e80bdb152 264 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 105 125 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMD11_RS12570 b430e9534948b2365832206e80bdb152 264 SUPERFAMILY SSF52096 8 263 6.54E-80 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS12570 b430e9534948b2365832206e80bdb152 264 Gene3D G3DSA:3.90.226.10 10 204 1.3E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS12570 b430e9534948b2365832206e80bdb152 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 262 3.8E-59 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS26605 6c6bb06ce0c71bcad66b829dd96ae3e4 285 Gene3D G3DSA:2.40.30.10 7 130 2.5E-35 T 06-07-2017 SMD11_RS26605 6c6bb06ce0c71bcad66b829dd96ae3e4 285 Gene3D G3DSA:3.40.50.80 133 276 8.1E-57 T 06-07-2017 SMD11_RS26605 6c6bb06ce0c71bcad66b829dd96ae3e4 285 SUPERFAMILY SSF63380 14 136 5.55E-12 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD11_RS26605 6c6bb06ce0c71bcad66b829dd96ae3e4 285 Pfam PF04954 Siderophore-interacting protein 138 255 6.7E-41 T 06-07-2017 IPR007037 Siderophore-interacting protein SMD11_RS26605 6c6bb06ce0c71bcad66b829dd96ae3e4 285 Pfam PF08021 Siderophore-interacting FAD-binding domain 16 130 2.7E-37 T 06-07-2017 IPR013113 FAD-binding 9, siderophore-interacting SMD11_RS25265 edadd9015db0e20b35e9816eaf2a3eb8 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 80 98 1.0E-26 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS25265 edadd9015db0e20b35e9816eaf2a3eb8 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 44 65 1.0E-26 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS25265 edadd9015db0e20b35e9816eaf2a3eb8 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 1.0E-26 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS25265 edadd9015db0e20b35e9816eaf2a3eb8 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 112 128 1.0E-26 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS25265 edadd9015db0e20b35e9816eaf2a3eb8 309 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 9 296 49.75 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS25265 edadd9015db0e20b35e9816eaf2a3eb8 309 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 14 292 1.4E-69 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS25265 edadd9015db0e20b35e9816eaf2a3eb8 309 PIRSF PIRSF001365 8 308 7.7E-78 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS25265 edadd9015db0e20b35e9816eaf2a3eb8 309 SUPERFAMILY SSF51569 10 295 2.72E-84 T 06-07-2017 SMD11_RS25265 edadd9015db0e20b35e9816eaf2a3eb8 309 SMART SM01130 9 295 1.0E-101 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS25265 edadd9015db0e20b35e9816eaf2a3eb8 309 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 142 172 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS25265 edadd9015db0e20b35e9816eaf2a3eb8 309 Pfam PF00701 Dihydrodipicolinate synthetase family 10 291 1.2E-71 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS25265 edadd9015db0e20b35e9816eaf2a3eb8 309 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 47 64 - T 06-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS25265 edadd9015db0e20b35e9816eaf2a3eb8 309 Gene3D G3DSA:3.20.20.70 10 294 1.9E-93 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS19840 61d401844f35edc7804697fb0378556d 899 Gene3D G3DSA:1.10.439.10 2 168 2.6E-58 T 06-07-2017 IPR023343 Penicillin amidase type, domain1 GO:0016811 SMD11_RS19840 61d401844f35edc7804697fb0378556d 899 Gene3D G3DSA:2.30.120.10 372 454 1.3E-23 T 06-07-2017 SMD11_RS19840 61d401844f35edc7804697fb0378556d 899 SUPERFAMILY SSF56235 278 690 3.09E-211 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS19840 61d401844f35edc7804697fb0378556d 899 SUPERFAMILY SSF56235 717 899 3.09E-211 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS19840 61d401844f35edc7804697fb0378556d 899 SUPERFAMILY SSF56235 3 197 3.09E-211 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS19840 61d401844f35edc7804697fb0378556d 899 PIRSF PIRSF001227 1 899 1.2E-259 T 06-07-2017 IPR014395 Penicillin acylase GO:0016811 SMD11_RS19840 61d401844f35edc7804697fb0378556d 899 Gene3D G3DSA:3.60.20.10 290 371 2.8E-115 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS19840 61d401844f35edc7804697fb0378556d 899 Gene3D G3DSA:3.60.20.10 463 673 2.8E-115 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS19840 61d401844f35edc7804697fb0378556d 899 Gene3D G3DSA:3.60.20.10 721 738 2.8E-115 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS19840 61d401844f35edc7804697fb0378556d 899 Pfam PF01804 Penicillin amidase 7 888 2.6E-244 T 06-07-2017 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 Pfam PF00365 Phosphofructokinase 2 297 2.3E-101 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 SUPERFAMILY SSF53784 1 332 9.68E-121 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 06-07-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 323 3.7E-147 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 Gene3D G3DSA:3.40.50.450 1 212 3.6E-72 T 06-07-2017 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 340 43.329 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 PIRSF PIRSF000532 1 339 1.2E-116 T 06-07-2017 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.2E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.2E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.2E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.2E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.2E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 1.2E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 1.2E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 1.2E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS28865 9f2155b7e1770a13430fc3f41b5575c6 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.2E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS09430 73543edc318f773f2a64ba867847d532 387 Gene3D G3DSA:3.40.190.10 51 174 2.9E-11 T 06-07-2017 SMD11_RS09430 73543edc318f773f2a64ba867847d532 387 Pfam PF13343 Bacterial extracellular solute-binding protein 108 343 1.5E-23 T 06-07-2017 SMD11_RS09430 73543edc318f773f2a64ba867847d532 387 SUPERFAMILY SSF53850 43 385 4.29E-60 T 06-07-2017 SMD11_RS09430 73543edc318f773f2a64ba867847d532 387 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 122 135 2.4E-14 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD11_RS09430 73543edc318f773f2a64ba867847d532 387 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 280 299 2.4E-14 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD11_RS09430 73543edc318f773f2a64ba867847d532 387 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 179 193 2.4E-14 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD11_RS09430 73543edc318f773f2a64ba867847d532 387 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 106 120 2.4E-14 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD11_RS09430 73543edc318f773f2a64ba867847d532 387 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 154 170 2.4E-14 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD11_RS09430 73543edc318f773f2a64ba867847d532 387 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 236 255 2.4E-14 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SMD11_RS09430 73543edc318f773f2a64ba867847d532 387 Gene3D G3DSA:3.40.190.10 175 329 1.5E-40 T 06-07-2017 SMD11_RS33555 0432762cef72104b06698f16ed4eddc5 495 SUPERFAMILY SSF89796 230 435 2.35E-42 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS33555 0432762cef72104b06698f16ed4eddc5 495 SUPERFAMILY SSF89796 42 212 8.24E-15 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS33555 0432762cef72104b06698f16ed4eddc5 495 Gene3D G3DSA:3.40.50.10540 229 432 1.0E-47 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS33555 0432762cef72104b06698f16ed4eddc5 495 Pfam PF02515 CoA-transferase family III 232 468 1.4E-36 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 SMD11_RS24475 2e6b0039d16b6c10d8f7b367ca29a87b 319 Pfam PF01795 MraW methylase family 5 313 5.2E-111 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD11_RS24475 2e6b0039d16b6c10d8f7b367ca29a87b 319 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 314 35.979 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD11_RS24475 2e6b0039d16b6c10d8f7b367ca29a87b 319 Gene3D G3DSA:1.10.150.170 117 221 1.6E-34 T 06-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD11_RS24475 2e6b0039d16b6c10d8f7b367ca29a87b 319 Gene3D G3DSA:3.40.50.150 222 316 4.8E-49 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS24475 2e6b0039d16b6c10d8f7b367ca29a87b 319 Gene3D G3DSA:3.40.50.150 7 114 4.8E-49 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS24475 2e6b0039d16b6c10d8f7b367ca29a87b 319 SUPERFAMILY SSF81799 118 219 7.06E-32 T 06-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD11_RS24475 2e6b0039d16b6c10d8f7b367ca29a87b 319 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 313 3.7E-91 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD11_RS24475 2e6b0039d16b6c10d8f7b367ca29a87b 319 SUPERFAMILY SSF53335 7 117 9.92E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS24475 2e6b0039d16b6c10d8f7b367ca29a87b 319 SUPERFAMILY SSF53335 219 314 9.92E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS24475 2e6b0039d16b6c10d8f7b367ca29a87b 319 PIRSF PIRSF004486 1 315 2.6E-97 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 13 139 1.0E-51 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 13 376 1.6E-135 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 PRINTS PR00097 Anthranilate synthase component II signature 259 270 1.8E-5 T 06-07-2017 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 PRINTS PR00097 Anthranilate synthase component II signature 350 363 1.8E-5 T 06-07-2017 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 PRINTS PR00097 Anthranilate synthase component II signature 231 240 1.8E-5 T 06-07-2017 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 SUPERFAMILY SSF52317 160 378 2.22E-50 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 SMART SM01097 11 141 8.5E-86 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 Gene3D G3DSA:3.40.50.880 162 378 9.2E-63 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 259 275 5.6E-30 T 06-07-2017 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 276 293 5.6E-30 T 06-07-2017 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 189 203 5.6E-30 T 06-07-2017 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 228 242 5.6E-30 T 06-07-2017 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 301 312 5.6E-30 T 06-07-2017 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 350 363 8.0E-11 T 06-07-2017 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 231 240 8.0E-11 T 06-07-2017 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 259 270 8.0E-11 T 06-07-2017 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 Gene3D G3DSA:3.50.30.20 12 146 2.3E-58 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 Pfam PF00117 Glutamine amidotransferase class-I 192 373 1.1E-37 T 06-07-2017 IPR017926 Glutamine amidotransferase SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 11 379 46.209 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27360 f15c361590b16b143843a9451ee940f7 380 SUPERFAMILY SSF52021 12 146 9.68E-56 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS22710 bb38e2f15a661ae42eb1378f4dca93ad 499 Pfam PF04138 GtrA-like protein 335 449 3.1E-12 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 SMD11_RS22710 bb38e2f15a661ae42eb1378f4dca93ad 499 SUPERFAMILY SSF53448 81 271 3.5E-28 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS22710 bb38e2f15a661ae42eb1378f4dca93ad 499 Gene3D G3DSA:3.90.550.10 87 265 6.6E-14 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS22710 bb38e2f15a661ae42eb1378f4dca93ad 499 Pfam PF00535 Glycosyl transferase family 2 88 263 3.7E-23 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD11_RS14940 462dc54a72e76a39df08492f59c86d0c 616 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 256 564 1.3E-99 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal SMD11_RS14940 462dc54a72e76a39df08492f59c86d0c 616 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 33 234 1.5E-12 T 06-07-2017 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 SMD11_RS23615 07a54179c739ed9bff4544d368611957 284 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 247 5.9E-73 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SMD11_RS23615 07a54179c739ed9bff4544d368611957 284 Gene3D G3DSA:3.40.1390.30 115 221 1.3E-35 T 06-07-2017 SMD11_RS23615 07a54179c739ed9bff4544d368611957 284 SUPERFAMILY SSF102705 4 269 1.83E-83 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SMD11_RS23615 07a54179c739ed9bff4544d368611957 284 Gene3D G3DSA:3.40.1390.30 4 114 1.6E-41 T 06-07-2017 SMD11_RS23615 07a54179c739ed9bff4544d368611957 284 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 239 1.7E-50 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SMD11_RS05345 a6baffcd2c231c9632bad174bd14ba3d 299 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 14 294 1.4E-94 T 06-07-2017 IPR017827 Squalene synthase HpnC SMD11_RS05345 a6baffcd2c231c9632bad174bd14ba3d 299 SUPERFAMILY SSF48576 15 297 3.31E-55 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS05345 a6baffcd2c231c9632bad174bd14ba3d 299 Pfam PF00494 Squalene/phytoene synthase 15 284 4.4E-65 T 06-07-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 SMD11_RS05345 a6baffcd2c231c9632bad174bd14ba3d 299 Gene3D G3DSA:1.10.600.10 18 288 5.0E-46 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS11790 afc411d85d98ef80ef13b77d1b8cda12 431 SMART SM00924 178 281 7.7E-35 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain SMD11_RS11790 afc411d85d98ef80ef13b77d1b8cda12 431 SUPERFAMILY SSF50346 11 72 2.04E-5 T 06-07-2017 IPR011033 PRC-barrel-like SMD11_RS11790 afc411d85d98ef80ef13b77d1b8cda12 431 SUPERFAMILY SSF54631 280 417 5.37E-23 T 06-07-2017 SMD11_RS11790 afc411d85d98ef80ef13b77d1b8cda12 431 Gene3D G3DSA:3.10.580.10 280 405 1.6E-18 T 06-07-2017 SMD11_RS11790 afc411d85d98ef80ef13b77d1b8cda12 431 Pfam PF00571 CBS domain 351 405 1.1E-4 T 06-07-2017 IPR000644 CBS domain SMD11_RS11790 afc411d85d98ef80ef13b77d1b8cda12 431 Pfam PF00571 CBS domain 282 343 0.0022 T 06-07-2017 IPR000644 CBS domain SMD11_RS11790 afc411d85d98ef80ef13b77d1b8cda12 431 Gene3D G3DSA:1.25.60.10 159 276 4.5E-41 T 06-07-2017 SMD11_RS11790 afc411d85d98ef80ef13b77d1b8cda12 431 Pfam PF03448 MgtE intracellular N domain 178 278 5.9E-27 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain SMD11_RS11790 afc411d85d98ef80ef13b77d1b8cda12 431 SUPERFAMILY SSF158791 166 278 1.7E-31 T 06-07-2017 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3326 3341 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1382 1619 2.8E-75 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 633 886 1.1E-81 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Gene3D G3DSA:1.10.1200.10 3854 3928 5.0E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF14765 Polyketide synthase dehydratase 1984 2266 5.0E-55 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SUPERFAMILY SSF53901 631 1004 5.77E-95 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SUPERFAMILY SSF53901 1039 1060 5.77E-95 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SUPERFAMILY SSF47336 3295 3384 1.44E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF08242 Methyltransferase domain 2916 3020 4.7E-14 T 06-07-2017 IPR013217 Methyltransferase type 12 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SUPERFAMILY SSF47336 526 647 5.37E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SMART SM00823 Phosphopantetheine attachment site 532 603 9.1E-16 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SMART SM00823 Phosphopantetheine attachment site 3861 3930 6.6E-8 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SMART SM00823 Phosphopantetheine attachment site 1277 1349 1.7E-13 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SMART SM00823 Phosphopantetheine attachment site 3300 3370 6.4E-15 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SUPERFAMILY SSF52777 3408 3591 4.89E-34 T 06-07-2017 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF13745 HxxPF-repeated domain 3732 3828 3.4E-13 T 06-07-2017 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SMART SM01294 533 599 0.0014 T 06-07-2017 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SMART SM01294 1279 1345 5.3E-8 T 06-07-2017 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SUPERFAMILY SSF53335 2842 3075 7.56E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1627 1745 2.3E-40 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 894 1011 2.0E-42 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SUPERFAMILY SSF51735 86 252 6.3E-8 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SUPERFAMILY SSF51735 2478 2711 1.89E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Gene3D G3DSA:1.10.1200.10 532 639 2.0E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF08659 KR domain 2482 2659 2.0E-40 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF08659 KR domain 267 452 3.1E-52 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SUPERFAMILY SSF51735 2269 2468 9.73E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SUPERFAMILY SSF47336 1277 1396 1.7E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SUPERFAMILY SSF47336 3859 3924 1.18E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Gene3D G3DSA:3.40.50.150 2880 3080 2.0E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SUPERFAMILY SSF52777 3598 3846 2.11E-51 T 06-07-2017 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SMART SM00826 1984 2147 1.2E-25 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Gene3D G3DSA:3.40.50.720 265 485 1.7E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Gene3D G3DSA:3.40.50.720 2480 2677 4.6E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Gene3D G3DSA:3.40.47.10 1384 1631 6.1E-82 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3885 3900 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SMART SM00825 Beta-ketoacyl synthase 635 1064 9.0E-197 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SMART SM00825 Beta-ketoacyl synthase 1384 1798 1.3E-183 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF00668 Condensation domain 3408 3710 1.0E-58 T 06-07-2017 IPR001242 Condensation domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF00550 Phosphopantetheine attachment site 3864 3925 2.4E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF00550 Phosphopantetheine attachment site 534 599 1.5E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF00550 Phosphopantetheine attachment site 1280 1345 1.4E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF00550 Phosphopantetheine attachment site 3302 3365 1.0E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Gene3D G3DSA:3.40.47.10 1632 1799 6.3E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Gene3D G3DSA:3.40.47.10 899 1062 3.3E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1014 1122 7.1E-14 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1748 1857 6.1E-10 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Gene3D G3DSA:3.40.47.10 640 898 2.2E-88 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1304 1319 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2482 2661 5.7E-29 T 06-07-2017 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 267 453 5.7E-45 T 06-07-2017 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SUPERFAMILY SSF51735 262 506 7.38E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Gene3D G3DSA:1.10.1200.10 3299 3366 3.0E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 Gene3D G3DSA:1.10.1200.10 1280 1350 4.7E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SUPERFAMILY SSF53901 1773 1793 8.57E-84 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29975 5a13a0078150ff833a1c6cfebbc6d34d 3950 SUPERFAMILY SSF53901 1380 1740 8.57E-84 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS30205 542b30f8ec13fcdd1b71aee34dc1841f 205 Pfam PF00857 Isochorismatase family 26 196 4.8E-31 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS30205 542b30f8ec13fcdd1b71aee34dc1841f 205 Gene3D G3DSA:3.40.50.850 23 203 4.4E-41 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS30205 542b30f8ec13fcdd1b71aee34dc1841f 205 SUPERFAMILY SSF52499 14 203 8.5E-41 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS10850 694200f0e339717542fbe164759e932c 359 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 359 37.926 T 06-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 SMD11_RS10850 694200f0e339717542fbe164759e932c 359 Gene3D G3DSA:1.20.58.410 6 88 7.5E-16 T 06-07-2017 SMD11_RS10850 694200f0e339717542fbe164759e932c 359 SMART SM00937 63 181 9.0E-55 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 SMD11_RS10850 694200f0e339717542fbe164759e932c 359 Gene3D G3DSA:3.30.160.20 213 291 1.4E-33 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain SMD11_RS10850 694200f0e339717542fbe164759e932c 359 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 230 246 - T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SMD11_RS10850 694200f0e339717542fbe164759e932c 359 Pfam PF00472 RF-1 domain 214 323 1.0E-40 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SMD11_RS10850 694200f0e339717542fbe164759e932c 359 Pfam PF03462 PCRF domain 11 206 3.1E-67 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 SMD11_RS10850 694200f0e339717542fbe164759e932c 359 SUPERFAMILY SSF75620 8 355 2.75E-126 T 06-07-2017 SMD11_RS10850 694200f0e339717542fbe164759e932c 359 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 356 5.3E-150 T 06-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 SMD11_RS06270 a4c08217448f9eec4823ff680578fcf8 309 Gene3D G3DSA:1.10.601.10 81 153 4.1E-15 T 06-07-2017 SMD11_RS06270 a4c08217448f9eec4823ff680578fcf8 309 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 80 303 1.9E-82 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS06270 a4c08217448f9eec4823ff680578fcf8 309 SUPERFAMILY SSF88659 159 234 8.72E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS06270 a4c08217448f9eec4823ff680578fcf8 309 SUPERFAMILY SSF88659 227 304 4.3E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS06270 a4c08217448f9eec4823ff680578fcf8 309 Gene3D G3DSA:1.10.10.10 155 209 1.5E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06270 a4c08217448f9eec4823ff680578fcf8 309 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 83 302 1.4E-27 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS06270 a4c08217448f9eec4823ff680578fcf8 309 SUPERFAMILY SSF88946 79 155 2.22E-23 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS06270 a4c08217448f9eec4823ff680578fcf8 309 Gene3D G3DSA:1.10.10.10 247 303 1.0E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06270 a4c08217448f9eec4823ff680578fcf8 309 PRINTS PR00046 Major sigma-70 factor signature 257 269 2.2E-6 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS06270 a4c08217448f9eec4823ff680578fcf8 309 PRINTS PR00046 Major sigma-70 factor signature 110 123 2.2E-6 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS06270 a4c08217448f9eec4823ff680578fcf8 309 PRINTS PR00046 Major sigma-70 factor signature 274 289 2.2E-6 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS06270 a4c08217448f9eec4823ff680578fcf8 309 Pfam PF04545 Sigma-70, region 4 254 300 2.2E-17 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS06270 a4c08217448f9eec4823ff680578fcf8 309 Pfam PF04542 Sigma-70 region 2 87 155 1.9E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS06270 a4c08217448f9eec4823ff680578fcf8 309 Pfam PF04539 Sigma-70 region 3 165 218 3.4E-7 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS09305 b171d2dbb41f33f99d822806d1d1688f 644 Gene3D G3DSA:1.20.140.10 267 440 1.0E-45 T 06-07-2017 SMD11_RS09305 b171d2dbb41f33f99d822806d1d1688f 644 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 60 165 3.8E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS09305 b171d2dbb41f33f99d822806d1d1688f 644 SUPERFAMILY SSF47203 278 437 4.99E-33 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS09305 b171d2dbb41f33f99d822806d1d1688f 644 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 278 436 1.8E-27 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS09305 b171d2dbb41f33f99d822806d1d1688f 644 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 170 266 2.0E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS09305 b171d2dbb41f33f99d822806d1d1688f 644 Gene3D G3DSA:1.10.540.10 30 168 4.4E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS09305 b171d2dbb41f33f99d822806d1d1688f 644 SUPERFAMILY SSF56645 60 288 4.45E-58 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS09305 b171d2dbb41f33f99d822806d1d1688f 644 Gene3D G3DSA:2.40.110.10 170 266 1.7E-32 T 06-07-2017 SMD11_RS02835 f5f545e4afc8b57d1021c9dd73a2bc27 253 Pfam PF13411 MerR HTH family regulatory protein 6 71 2.1E-16 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS02835 f5f545e4afc8b57d1021c9dd73a2bc27 253 Gene3D G3DSA:1.10.1660.10 6 113 2.1E-26 T 06-07-2017 SMD11_RS02835 f5f545e4afc8b57d1021c9dd73a2bc27 253 SMART SM00422 3 72 1.2E-20 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS02835 f5f545e4afc8b57d1021c9dd73a2bc27 253 SUPERFAMILY SSF46955 5 108 1.87E-25 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS02835 f5f545e4afc8b57d1021c9dd73a2bc27 253 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS02835 f5f545e4afc8b57d1021c9dd73a2bc27 253 Gene3D G3DSA:1.10.490.50 166 251 1.2E-15 T 06-07-2017 IPR012925 TipAS antibiotic-recognition domain SMD11_RS02835 f5f545e4afc8b57d1021c9dd73a2bc27 253 Pfam PF07739 TipAS antibiotic-recognition domain 147 247 2.2E-12 T 06-07-2017 IPR012925 TipAS antibiotic-recognition domain SMD11_RS02835 f5f545e4afc8b57d1021c9dd73a2bc27 253 SUPERFAMILY SSF89082 167 248 4.05E-11 T 06-07-2017 IPR012925 TipAS antibiotic-recognition domain SMD11_RS25810 11313f3e0997b0ab4f71d769aa6fb6e4 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 1.8E-81 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain SMD11_RS25810 11313f3e0997b0ab4f71d769aa6fb6e4 371 Gene3D G3DSA:3.40.50.1770 2 177 1.4E-56 T 06-07-2017 SMD11_RS25810 11313f3e0997b0ab4f71d769aa6fb6e4 371 SMART SM01003 4 137 1.3E-79 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal SMD11_RS25810 11313f3e0997b0ab4f71d769aa6fb6e4 371 PIRSF PIRSF000183 1 371 2.3E-168 T 06-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 SMD11_RS25810 11313f3e0997b0ab4f71d769aa6fb6e4 371 SUPERFAMILY SSF51735 137 303 4.27E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS25810 11313f3e0997b0ab4f71d769aa6fb6e4 371 Gene3D G3DSA:3.40.50.1770 195 357 5.2E-31 T 06-07-2017 SMD11_RS25810 11313f3e0997b0ab4f71d769aa6fb6e4 371 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 06-07-2017 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 SMD11_RS25810 11313f3e0997b0ab4f71d769aa6fb6e4 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 3.9E-48 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal SMD11_RS25810 11313f3e0997b0ab4f71d769aa6fb6e4 371 Gene3D G3DSA:3.50.50.60 178 194 1.6E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS25810 11313f3e0997b0ab4f71d769aa6fb6e4 371 SMART SM01002 149 297 5.6E-82 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain SMD11_RS25810 11313f3e0997b0ab4f71d769aa6fb6e4 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 2 367 4.2E-177 T 06-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 SMD11_RS25810 11313f3e0997b0ab4f71d769aa6fb6e4 371 SUPERFAMILY SSF52283 305 360 3.23E-66 T 06-07-2017 SMD11_RS25810 11313f3e0997b0ab4f71d769aa6fb6e4 371 SUPERFAMILY SSF52283 2 137 3.23E-66 T 06-07-2017 SMD11_RS18905 500968bb56344e0e691f6da68db4bef6 93 PIRSF PIRSF002144 1 93 1.8E-31 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18905 500968bb56344e0e691f6da68db4bef6 93 SUPERFAMILY SSF54570 3 84 5.62E-35 T 06-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18905 500968bb56344e0e691f6da68db4bef6 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 1.8E-46 T 06-07-2017 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMD11_RS18905 500968bb56344e0e691f6da68db4bef6 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 4.6E-24 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18905 500968bb56344e0e691f6da68db4bef6 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 4.6E-24 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18905 500968bb56344e0e691f6da68db4bef6 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 4.6E-24 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18905 500968bb56344e0e691f6da68db4bef6 93 Gene3D G3DSA:3.30.860.10 1 92 4.9E-41 T 06-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18905 500968bb56344e0e691f6da68db4bef6 93 Pfam PF00203 Ribosomal protein S19 3 83 4.5E-37 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18905 500968bb56344e0e691f6da68db4bef6 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.046 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18905 500968bb56344e0e691f6da68db4bef6 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 06-07-2017 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS09630 3cbc8620f2fad5201ddef29d1d24bcfa 808 Pfam PF08335 GlnD PII-uridylyltransferase 205 278 9.5E-9 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 SMD11_RS09630 3cbc8620f2fad5201ddef29d1d24bcfa 808 SUPERFAMILY SSF81301 34 153 3.27E-15 T 06-07-2017 SMD11_RS09630 3cbc8620f2fad5201ddef29d1d24bcfa 808 Gene3D G3DSA:1.10.3210.10 413 577 3.3E-18 T 06-07-2017 IPR006674 HD domain SMD11_RS09630 3cbc8620f2fad5201ddef29d1d24bcfa 808 Gene3D G3DSA:3.30.70.260 735 790 2.7E-7 T 06-07-2017 SMD11_RS09630 3cbc8620f2fad5201ddef29d1d24bcfa 808 Pfam PF01966 HD domain 435 551 3.6E-13 T 06-07-2017 IPR006674 HD domain SMD11_RS09630 3cbc8620f2fad5201ddef29d1d24bcfa 808 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 34 603 1.4E-184 T 06-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 SMD11_RS09630 3cbc8620f2fad5201ddef29d1d24bcfa 808 SUPERFAMILY SSF81593 176 277 2.12E-7 T 06-07-2017 SMD11_RS09630 3cbc8620f2fad5201ddef29d1d24bcfa 808 Gene3D G3DSA:3.30.460.10 57 118 5.7E-5 T 06-07-2017 SMD11_RS09630 3cbc8620f2fad5201ddef29d1d24bcfa 808 SUPERFAMILY SSF55021 734 787 4.08E-8 T 06-07-2017 SMD11_RS09630 3cbc8620f2fad5201ddef29d1d24bcfa 808 SMART SM00471 430 562 4.3E-9 T 06-07-2017 IPR003607 HD/PDEase domain SMD11_RS09630 3cbc8620f2fad5201ddef29d1d24bcfa 808 SUPERFAMILY SSF109604 400 531 3.45E-15 T 06-07-2017 SMD11_RS09630 3cbc8620f2fad5201ddef29d1d24bcfa 808 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 808 86.76 T 06-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 SMD11_RS25630 3c755c8c421b185af4671b4cdf75a915 79 Pfam PF03777 Small secreted domain (DUF320) 23 78 2.5E-28 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD11_RS27795 33482aaa446f537779726f89087456fd 353 SUPERFAMILY SSF53807 58 350 5.1E-40 T 06-07-2017 SMD11_RS27795 33482aaa446f537779726f89087456fd 353 Gene3D G3DSA:3.40.50.1980 58 201 2.9E-9 T 06-07-2017 SMD11_RS27795 33482aaa446f537779726f89087456fd 353 Gene3D G3DSA:3.40.50.1980 209 351 9.7E-25 T 06-07-2017 SMD11_RS27795 33482aaa446f537779726f89087456fd 353 Pfam PF01497 Periplasmic binding protein 62 326 3.0E-21 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD11_RS23190 c1e345d7df9eaef390d969c77fe6af69 81 Gene3D G3DSA:1.10.1200.10 2 80 1.9E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS23190 c1e345d7df9eaef390d969c77fe6af69 81 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 37 79 5.0E-16 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS23190 c1e345d7df9eaef390d969c77fe6af69 81 SUPERFAMILY SSF47336 2 80 1.02E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS23190 c1e345d7df9eaef390d969c77fe6af69 81 Hamap MF_01217 Acyl carrier protein [acpP]. 6 80 16.984 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS23190 c1e345d7df9eaef390d969c77fe6af69 81 Pfam PF00550 Phosphopantetheine attachment site 12 76 5.8E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29760 ce53e0149bf8e67b46c1ccd45e253dcd 259 SMART SM00448 41 149 2.4E-36 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS29760 ce53e0149bf8e67b46c1ccd45e253dcd 259 Gene3D G3DSA:3.40.50.2300 29 158 4.5E-35 T 06-07-2017 SMD11_RS29760 ce53e0149bf8e67b46c1ccd45e253dcd 259 SUPERFAMILY SSF46894 160 256 1.53E-26 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS29760 ce53e0149bf8e67b46c1ccd45e253dcd 259 SUPERFAMILY SSF52172 33 164 4.84E-35 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS29760 ce53e0149bf8e67b46c1ccd45e253dcd 259 SMART SM00862 184 256 5.1E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS29760 ce53e0149bf8e67b46c1ccd45e253dcd 259 Pfam PF00486 Transcriptional regulatory protein, C terminal 184 256 1.1E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS29760 ce53e0149bf8e67b46c1ccd45e253dcd 259 Pfam PF00072 Response regulator receiver domain 43 150 1.4E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS29760 ce53e0149bf8e67b46c1ccd45e253dcd 259 Gene3D G3DSA:1.10.10.10 161 256 8.9E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS29505 e15b9f98b80d814d17adbbefcbf97a46 338 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 219 3.6E-52 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMD11_RS29505 e15b9f98b80d814d17adbbefcbf97a46 338 SMART SM01092 225 323 2.9E-26 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMD11_RS29505 e15b9f98b80d814d17adbbefcbf97a46 338 Gene3D G3DSA:3.30.390.50 223 321 1.0E-32 T 06-07-2017 SMD11_RS29505 e15b9f98b80d814d17adbbefcbf97a46 338 SUPERFAMILY SSF55447 225 323 6.41E-26 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMD11_RS29505 e15b9f98b80d814d17adbbefcbf97a46 338 SUPERFAMILY SSF56176 2 219 1.21E-60 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS29505 e15b9f98b80d814d17adbbefcbf97a46 338 Gene3D G3DSA:3.30.43.10 2 51 2.0E-17 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS29505 e15b9f98b80d814d17adbbefcbf97a46 338 Gene3D G3DSA:3.30.465.10 157 219 2.4E-36 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS29505 e15b9f98b80d814d17adbbefcbf97a46 338 Gene3D G3DSA:3.30.465.10 56 113 2.4E-36 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS29505 e15b9f98b80d814d17adbbefcbf97a46 338 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 225 320 3.6E-17 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMD11_RS07750 805398e8e350afddd8aee940ecb41db1 432 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 267 2.3E-32 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS07750 805398e8e350afddd8aee940ecb41db1 432 Gene3D G3DSA:3.40.47.10 4 280 1.4E-44 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07750 805398e8e350afddd8aee940ecb41db1 432 SUPERFAMILY SSF53901 6 272 4.94E-47 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07750 805398e8e350afddd8aee940ecb41db1 432 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 275 388 4.5E-25 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS07750 805398e8e350afddd8aee940ecb41db1 432 SMART SM00825 Beta-ketoacyl synthase 8 410 5.5E-10 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS07750 805398e8e350afddd8aee940ecb41db1 432 Gene3D G3DSA:3.40.47.10 285 431 2.0E-38 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07750 805398e8e350afddd8aee940ecb41db1 432 SUPERFAMILY SSF53901 237 431 2.63E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS01440 dcb0dce669c3c65e95d7235c08292995 274 SUPERFAMILY SSF48008 141 260 2.48E-12 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS01440 dcb0dce669c3c65e95d7235c08292995 274 Pfam PF00392 Bacterial regulatory proteins, gntR family 58 114 2.2E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS01440 dcb0dce669c3c65e95d7235c08292995 274 SMART SM00895 142 265 0.0028 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS01440 dcb0dce669c3c65e95d7235c08292995 274 Gene3D G3DSA:1.10.10.10 48 114 2.7E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01440 dcb0dce669c3c65e95d7235c08292995 274 SUPERFAMILY SSF46785 52 123 8.09E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01440 dcb0dce669c3c65e95d7235c08292995 274 SMART SM00345 60 117 6.0E-4 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS01440 dcb0dce669c3c65e95d7235c08292995 274 Gene3D G3DSA:1.20.120.530 136 260 9.7E-13 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS01440 dcb0dce669c3c65e95d7235c08292995 274 Pfam PF07729 FCD domain 143 260 3.5E-11 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS11445 3bf100794dbdbb7bab117770946d6844 566 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 112 475 9.4E-57 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain SMD11_RS11445 3bf100794dbdbb7bab117770946d6844 566 SUPERFAMILY SSF53850 57 556 7.6E-88 T 06-07-2017 SMD11_RS11445 3bf100794dbdbb7bab117770946d6844 566 Gene3D G3DSA:3.40.190.10 192 321 7.1E-24 T 06-07-2017 SMD11_RS11445 3bf100794dbdbb7bab117770946d6844 566 PIRSF PIRSF002741 4 566 5.9E-59 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD11_RS11445 3bf100794dbdbb7bab117770946d6844 566 Gene3D G3DSA:3.10.105.10 322 537 5.1E-50 T 06-07-2017 SMD11_RS11445 3bf100794dbdbb7bab117770946d6844 566 Gene3D G3DSA:3.90.76.10 77 191 9.3E-16 T 06-07-2017 SMD11_RS02670 742744b88bf3b31ab2142452cd24f02d 557 SUPERFAMILY SSF51905 185 420 4.81E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02670 742744b88bf3b31ab2142452cd24f02d 557 SUPERFAMILY SSF51905 9 104 4.81E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02670 742744b88bf3b31ab2142452cd24f02d 557 Gene3D G3DSA:3.50.50.60 7 105 3.6E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02670 742744b88bf3b31ab2142452cd24f02d 557 Gene3D G3DSA:3.50.50.60 185 199 3.6E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02670 742744b88bf3b31ab2142452cd24f02d 557 Gene3D G3DSA:3.50.50.60 200 415 2.2E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02670 742744b88bf3b31ab2142452cd24f02d 557 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 343 359 8.4E-15 T 06-07-2017 SMD11_RS02670 742744b88bf3b31ab2142452cd24f02d 557 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 8.4E-15 T 06-07-2017 SMD11_RS02670 742744b88bf3b31ab2142452cd24f02d 557 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 255 8.4E-15 T 06-07-2017 SMD11_RS02670 742744b88bf3b31ab2142452cd24f02d 557 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 374 396 8.4E-15 T 06-07-2017 SMD11_RS02670 742744b88bf3b31ab2142452cd24f02d 557 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 252 271 5.6E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS02670 742744b88bf3b31ab2142452cd24f02d 557 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 5.6E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS02670 742744b88bf3b31ab2142452cd24f02d 557 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 191 404 9.9E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02670 742744b88bf3b31ab2142452cd24f02d 557 Pfam PF04324 BFD-like [2Fe-2S] binding domain 468 515 2.2E-10 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain SMD11_RS02670 742744b88bf3b31ab2142452cd24f02d 557 Pfam PF13450 NAD(P)-binding Rossmann-like domain 13 55 3.4E-7 T 06-07-2017 SMD11_RS17725 d6b327b6b705fccac794ab44a3a75e62 268 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 9 142 1.3E-7 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G SMD11_RS17725 d6b327b6b705fccac794ab44a3a75e62 268 Gene3D G3DSA:3.30.530.20 1 143 3.2E-24 T 06-07-2017 IPR023393 START-like domain SMD11_RS17725 d6b327b6b705fccac794ab44a3a75e62 268 SUPERFAMILY SSF55961 1 142 8.25E-21 T 06-07-2017 SMD11_RS17975 370bec3aff1d9d4b6fb33782b815be5e 1326 Gene3D G3DSA:3.40.50.300 277 425 5.2E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17975 370bec3aff1d9d4b6fb33782b815be5e 1326 Pfam PF11898 Domain of unknown function (DUF3418) 721 1323 2.3E-232 T 06-07-2017 IPR024590 RNA helicase HrpA, C-terminal SMD11_RS17975 370bec3aff1d9d4b6fb33782b815be5e 1326 Gene3D G3DSA:3.40.50.300 77 234 1.3E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17975 370bec3aff1d9d4b6fb33782b815be5e 1326 SMART SM00490 306 413 5.1E-13 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS17975 370bec3aff1d9d4b6fb33782b815be5e 1326 SMART SM00382 93 393 2.4E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS17975 370bec3aff1d9d4b6fb33782b815be5e 1326 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 626 707 2.1E-15 T 06-07-2017 IPR011709 Domain of unknown function DUF1605 SMD11_RS17975 370bec3aff1d9d4b6fb33782b815be5e 1326 Pfam PF04408 Helicase associated domain (HA2) 475 566 7.9E-18 T 06-07-2017 IPR007502 Helicase-associated domain GO:0004386 SMD11_RS17975 370bec3aff1d9d4b6fb33782b815be5e 1326 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 16 1323 0.0 T 06-07-2017 IPR010222 RNA helicase HrpA GO:0004004 SMD11_RS17975 370bec3aff1d9d4b6fb33782b815be5e 1326 SMART SM00847 473 568 9.6E-38 T 06-07-2017 IPR007502 Helicase-associated domain GO:0004386 SMD11_RS17975 370bec3aff1d9d4b6fb33782b815be5e 1326 Pfam PF00271 Helicase conserved C-terminal domain 286 412 6.9E-10 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS17975 370bec3aff1d9d4b6fb33782b815be5e 1326 Pfam PF00270 DEAD/DEAH box helicase 86 234 5.2E-6 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD11_RS17975 370bec3aff1d9d4b6fb33782b815be5e 1326 SUPERFAMILY SSF52540 75 610 9.14E-113 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17975 370bec3aff1d9d4b6fb33782b815be5e 1326 SMART SM00487 69 260 8.1E-27 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS25680 4675bac74b1e5828a349b508b11267a9 143 Gene3D G3DSA:3.30.370.10 47 135 4.0E-23 T 06-07-2017 IPR000468 Barstar (barnase inhibitor) SMD11_RS25680 4675bac74b1e5828a349b508b11267a9 143 Pfam PF01337 Barstar (barnase inhibitor) 49 133 1.6E-26 T 06-07-2017 IPR000468 Barstar (barnase inhibitor) SMD11_RS25680 4675bac74b1e5828a349b508b11267a9 143 SUPERFAMILY SSF52038 47 134 1.44E-21 T 06-07-2017 IPR000468 Barstar (barnase inhibitor) SMD11_RS08405 1fc6028102330e5b18e71b55a80f57ce 429 SUPERFAMILY SSF55205 11 417 1.1E-103 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SMD11_RS08405 1fc6028102330e5b18e71b55a80f57ce 429 Gene3D G3DSA:3.65.10.10 19 231 1.3E-53 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD11_RS08405 1fc6028102330e5b18e71b55a80f57ce 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 13 414 3.1E-101 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD11_RS08405 1fc6028102330e5b18e71b55a80f57ce 429 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 13 418 2.5E-115 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD11_RS08405 1fc6028102330e5b18e71b55a80f57ce 429 ProSitePatterns PS00885 EPSP synthase signature 2. 332 350 - T 06-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD11_RS08405 1fc6028102330e5b18e71b55a80f57ce 429 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 7 420 28.542 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD11_RS08405 1fc6028102330e5b18e71b55a80f57ce 429 PIRSF PIRSF000505 1 422 5.3E-130 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SMD11_RS08405 1fc6028102330e5b18e71b55a80f57ce 429 Gene3D G3DSA:3.65.10.10 232 416 9.8E-59 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD11_RS09765 b328bb2ef57ef6baa6d4d25a614b9e8e 382 Gene3D G3DSA:3.40.50.20 13 146 3.8E-37 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS09765 b328bb2ef57ef6baa6d4d25a614b9e8e 382 SUPERFAMILY SSF52440 13 155 1.53E-34 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS09765 b328bb2ef57ef6baa6d4d25a614b9e8e 382 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 124 135 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS09765 b328bb2ef57ef6baa6d4d25a614b9e8e 382 Pfam PF01820 D-ala D-ala ligase N-terminus 15 147 4.8E-34 T 06-07-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS09765 b328bb2ef57ef6baa6d4d25a614b9e8e 382 SUPERFAMILY SSF56059 157 376 1.04E-54 T 06-07-2017 SMD11_RS09765 b328bb2ef57ef6baa6d4d25a614b9e8e 382 Gene3D G3DSA:3.30.470.20 247 378 3.0E-48 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS09765 b328bb2ef57ef6baa6d4d25a614b9e8e 382 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 14 375 41.122 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS09765 b328bb2ef57ef6baa6d4d25a614b9e8e 382 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 15 374 8.9E-105 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS09765 b328bb2ef57ef6baa6d4d25a614b9e8e 382 Gene3D G3DSA:3.30.1490.20 168 245 1.2E-20 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS09765 b328bb2ef57ef6baa6d4d25a614b9e8e 382 PIRSF PIRSF039102 11 381 8.2E-110 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS09765 b328bb2ef57ef6baa6d4d25a614b9e8e 382 Pfam PF07478 D-ala D-ala ligase C-terminus 166 372 5.1E-67 T 06-07-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS09765 b328bb2ef57ef6baa6d4d25a614b9e8e 382 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 317 345 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS04360 160268a5a43f0795c210b68aa51faaa6 351 SUPERFAMILY SSF53067 2 312 6.48E-38 T 06-07-2017 SMD11_RS04360 160268a5a43f0795c210b68aa51faaa6 351 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 2 315 5.3E-122 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS04360 160268a5a43f0795c210b68aa51faaa6 351 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 3 310 2.3E-93 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS04360 160268a5a43f0795c210b68aa51faaa6 351 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 336 59.272 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS04360 160268a5a43f0795c210b68aa51faaa6 351 ProSitePatterns PS01016 Glycoprotease family signature. 94 114 - T 06-07-2017 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 SMD11_RS04360 160268a5a43f0795c210b68aa51faaa6 351 Gene3D G3DSA:3.30.420.40 2 142 2.0E-43 T 06-07-2017 SMD11_RS04360 160268a5a43f0795c210b68aa51faaa6 351 Pfam PF00814 Glycoprotease family 22 310 3.4E-95 T 06-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS04360 160268a5a43f0795c210b68aa51faaa6 351 Gene3D G3DSA:3.40.50.450 252 288 5.4E-5 T 06-07-2017 SMD11_RS04360 160268a5a43f0795c210b68aa51faaa6 351 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 74 94 7.8E-49 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS04360 160268a5a43f0795c210b68aa51faaa6 351 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 3 16 7.8E-49 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS04360 160268a5a43f0795c210b68aa51faaa6 351 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 7.8E-49 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS04360 160268a5a43f0795c210b68aa51faaa6 351 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 7.8E-49 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS04360 160268a5a43f0795c210b68aa51faaa6 351 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 95 114 7.8E-49 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS04360 160268a5a43f0795c210b68aa51faaa6 351 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 129 141 7.8E-49 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS06415 8cef169ba001d49264062e682a4a35cb 377 Gene3D G3DSA:1.10.540.10 38 97 1.3E-9 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS06415 8cef169ba001d49264062e682a4a35cb 377 SUPERFAMILY SSF47203 241 371 4.38E-5 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS06415 8cef169ba001d49264062e682a4a35cb 377 Gene3D G3DSA:2.40.110.10 132 223 1.3E-13 T 06-07-2017 SMD11_RS06415 8cef169ba001d49264062e682a4a35cb 377 SUPERFAMILY SSF56645 37 223 3.93E-28 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS13700 ba1767b5ef9747dfd8f5151160c39bd6 407 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 363 1.2E-28 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS13700 ba1767b5ef9747dfd8f5151160c39bd6 407 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 8 243 3.5E-54 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS13700 ba1767b5ef9747dfd8f5151160c39bd6 407 SUPERFAMILY SSF53901 6 251 4.51E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS13700 ba1767b5ef9747dfd8f5151160c39bd6 407 SUPERFAMILY SSF53901 213 405 6.29E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS13700 ba1767b5ef9747dfd8f5151160c39bd6 407 SMART SM00825 Beta-ketoacyl synthase 8 407 1.8E-13 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS13700 ba1767b5ef9747dfd8f5151160c39bd6 407 Gene3D G3DSA:3.40.47.10 263 405 1.4E-48 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS13700 ba1767b5ef9747dfd8f5151160c39bd6 407 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS13700 ba1767b5ef9747dfd8f5151160c39bd6 407 Gene3D G3DSA:3.40.47.10 10 259 1.9E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20025 bec57ad8051306637c8849ef22e16820 268 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 26 207 1.2E-63 T 06-07-2017 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 SMD11_RS20025 bec57ad8051306637c8849ef22e16820 268 Gene3D G3DSA:3.40.50.300 9 239 5.5E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20025 bec57ad8051306637c8849ef22e16820 268 SMART SM00382 42 231 1.2E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS20025 bec57ad8051306637c8849ef22e16820 268 Pfam PF00005 ABC transporter 35 178 5.5E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS20025 bec57ad8051306637c8849ef22e16820 268 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS20025 bec57ad8051306637c8849ef22e16820 268 SUPERFAMILY SSF52540 17 237 1.85E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31230 0fde2f313688dea0ce708712f4d12b7e 614 SUPERFAMILY SSF90123 46 358 2.62E-60 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS31230 0fde2f313688dea0ce708712f4d12b7e 614 SMART SM00382 394 580 2.3E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS31230 0fde2f313688dea0ce708712f4d12b7e 614 Gene3D G3DSA:3.40.50.300 369 599 5.6E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31230 0fde2f313688dea0ce708712f4d12b7e 614 SUPERFAMILY SSF52540 362 603 7.24E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31230 0fde2f313688dea0ce708712f4d12b7e 614 Pfam PF00005 ABC transporter 385 534 3.4E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS31230 0fde2f313688dea0ce708712f4d12b7e 614 Pfam PF00664 ABC transporter transmembrane region 60 326 8.3E-35 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS31230 0fde2f313688dea0ce708712f4d12b7e 614 Gene3D G3DSA:1.20.1560.10 46 357 2.3E-63 T 06-07-2017 SMD11_RS32655 a33628e326c6d97d6419f1d94fbbedcd 78 Gene3D G3DSA:1.10.1200.10 2 77 2.0E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32655 a33628e326c6d97d6419f1d94fbbedcd 78 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 35 76 8.0E-6 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS32655 a33628e326c6d97d6419f1d94fbbedcd 78 Pfam PF00550 Phosphopantetheine attachment site 8 74 5.7E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32655 a33628e326c6d97d6419f1d94fbbedcd 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 3 75 4.8E-21 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS32655 a33628e326c6d97d6419f1d94fbbedcd 78 Hamap MF_01217 Acyl carrier protein [acpP]. 4 78 16.134 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS32655 a33628e326c6d97d6419f1d94fbbedcd 78 SMART SM00823 Phosphopantetheine attachment site 6 78 0.0033 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32655 a33628e326c6d97d6419f1d94fbbedcd 78 SUPERFAMILY SSF47336 3 77 1.57E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS24365 ece508d0bbc451e744e4346b80d68f17 79 Pfam PF04324 BFD-like [2Fe-2S] binding domain 5 53 1.2E-11 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain SMD11_RS11670 d1fb329105e09c30386561c656bea84b 546 SMART SM00382 318 510 5.3E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS11670 d1fb329105e09c30386561c656bea84b 546 SMART SM00382 37 237 1.7E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS11670 d1fb329105e09c30386561c656bea84b 546 ProSitePatterns PS00211 ABC transporters family signature. 433 447 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS11670 d1fb329105e09c30386561c656bea84b 546 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 512 542 2.9E-6 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS11670 d1fb329105e09c30386561c656bea84b 546 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 275 4.5E-4 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS11670 d1fb329105e09c30386561c656bea84b 546 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS11670 d1fb329105e09c30386561c656bea84b 546 Gene3D G3DSA:3.40.50.300 288 534 1.3E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11670 d1fb329105e09c30386561c656bea84b 546 Gene3D G3DSA:3.40.50.300 8 261 1.9E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11670 d1fb329105e09c30386561c656bea84b 546 SUPERFAMILY SSF52540 8 259 4.72E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11670 d1fb329105e09c30386561c656bea84b 546 Pfam PF00005 ABC transporter 29 187 1.4E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS11670 d1fb329105e09c30386561c656bea84b 546 Pfam PF00005 ABC transporter 310 460 5.0E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS11670 d1fb329105e09c30386561c656bea84b 546 SUPERFAMILY SSF52540 289 531 8.5E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22060 60a5fce6416741644762e76c242e38e6 420 SMART SM00332 145 408 2.7E-12 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS22060 60a5fce6416741644762e76c242e38e6 420 Gene3D G3DSA:3.60.40.10 150 409 3.3E-48 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS22060 60a5fce6416741644762e76c242e38e6 420 SMART SM00331 154 410 3.8E-6 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS22060 60a5fce6416741644762e76c242e38e6 420 SUPERFAMILY SSF81606 149 410 3.14E-40 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS22060 60a5fce6416741644762e76c242e38e6 420 Pfam PF13672 Protein phosphatase 2C 162 375 1.2E-17 T 06-07-2017 SMD11_RS33175 b98f46bab1aa8111576c111e4128347f 209 Gene3D G3DSA:3.40.50.1240 3 208 1.5E-38 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS33175 b98f46bab1aa8111576c111e4128347f 209 SUPERFAMILY SSF53254 3 208 2.09E-38 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS33175 b98f46bab1aa8111576c111e4128347f 209 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 202 1.1E-35 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS33175 b98f46bab1aa8111576c111e4128347f 209 PIRSF PIRSF000709 1 203 2.1E-6 T 06-07-2017 SMD11_RS33175 b98f46bab1aa8111576c111e4128347f 209 SMART SM00855 3 160 6.4E-12 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS04630 4747a2a3f1890d84a05d7687a39bd337 333 Pfam PF00487 Fatty acid desaturase 84 300 3.1E-18 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 SMD11_RS04630 4747a2a3f1890d84a05d7687a39bd337 333 PRINTS PR00075 Fatty acid desaturase family 1 signature 282 296 7.4E-9 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD11_RS04630 4747a2a3f1890d84a05d7687a39bd337 333 PRINTS PR00075 Fatty acid desaturase family 1 signature 239 260 7.4E-9 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD11_RS04630 4747a2a3f1890d84a05d7687a39bd337 333 PRINTS PR00075 Fatty acid desaturase family 1 signature 100 120 7.4E-9 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD11_RS04630 4747a2a3f1890d84a05d7687a39bd337 333 PRINTS PR00075 Fatty acid desaturase family 1 signature 77 99 7.4E-9 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD11_RS22515 e977c50139c030987aa914ba8c118efb 213 Gene3D G3DSA:3.40.50.1240 6 201 1.8E-57 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS22515 e977c50139c030987aa914ba8c118efb 213 SUPERFAMILY SSF53254 6 204 1.22E-55 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS22515 e977c50139c030987aa914ba8c118efb 213 SMART SM00855 7 161 2.4E-24 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS22515 e977c50139c030987aa914ba8c118efb 213 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 10 19 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 SMD11_RS22515 e977c50139c030987aa914ba8c118efb 213 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 200 1.4E-55 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS08815 1de5b520697d0e6f75ae6d43a3ab079f 261 Pfam PF01726 LexA DNA binding domain 54 117 1.1E-29 T 06-07-2017 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 SMD11_RS08815 1de5b520697d0e6f75ae6d43a3ab079f 261 Gene3D G3DSA:1.10.10.10 55 121 1.8E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08815 1de5b520697d0e6f75ae6d43a3ab079f 261 Gene3D G3DSA:2.10.109.10 142 260 7.2E-45 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain SMD11_RS08815 1de5b520697d0e6f75ae6d43a3ab079f 261 Hamap MF_00015 LexA repressor [lexA]. 55 261 34.241 T 06-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 SMD11_RS08815 1de5b520697d0e6f75ae6d43a3ab079f 261 SUPERFAMILY SSF51306 141 259 2.09E-36 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C SMD11_RS08815 1de5b520697d0e6f75ae6d43a3ab079f 261 Pfam PF00717 Peptidase S24-like 180 244 1.4E-16 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B SMD11_RS08815 1de5b520697d0e6f75ae6d43a3ab079f 261 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 216 228 2.5E-11 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 SMD11_RS08815 1de5b520697d0e6f75ae6d43a3ab079f 261 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 177 187 2.5E-11 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 SMD11_RS08815 1de5b520697d0e6f75ae6d43a3ab079f 261 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 188 199 2.5E-11 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 SMD11_RS08815 1de5b520697d0e6f75ae6d43a3ab079f 261 TIGRFAM TIGR00498 lexA: repressor LexA 54 261 2.3E-75 T 06-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 SMD11_RS08815 1de5b520697d0e6f75ae6d43a3ab079f 261 SUPERFAMILY SSF46785 55 121 3.05E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03730 88009ecc07900281dfeb01e80d858aa7 357 Gene3D G3DSA:3.40.50.2300 199 354 1.9E-38 T 06-07-2017 SMD11_RS03730 88009ecc07900281dfeb01e80d858aa7 357 Gene3D G3DSA:1.10.260.40 7 57 9.5E-24 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS03730 88009ecc07900281dfeb01e80d858aa7 357 Gene3D G3DSA:3.40.50.2300 58 198 5.7E-14 T 06-07-2017 SMD11_RS03730 88009ecc07900281dfeb01e80d858aa7 357 SMART SM00354 8 78 2.8E-21 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS03730 88009ecc07900281dfeb01e80d858aa7 357 SUPERFAMILY SSF53822 82 337 3.93E-43 T 06-07-2017 IPR028082 Periplasmic binding protein-like I SMD11_RS03730 88009ecc07900281dfeb01e80d858aa7 357 ProSitePatterns PS00356 LacI-type HTH domain signature. 11 29 - T 06-07-2017 SMD11_RS03730 88009ecc07900281dfeb01e80d858aa7 357 SUPERFAMILY SSF47413 7 63 1.72E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS03730 88009ecc07900281dfeb01e80d858aa7 357 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 55 1.5E-16 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS03730 88009ecc07900281dfeb01e80d858aa7 357 Pfam PF13377 Periplasmic binding protein-like domain 194 352 5.4E-31 T 06-07-2017 SMD11_RS31375 b12ebee2b008a8ab8f1586aa1085c715 310 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 9 295 5.7E-111 T 06-07-2017 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 SMD11_RS31375 b12ebee2b008a8ab8f1586aa1085c715 310 PIRSF PIRSF000103 2 303 7.7E-74 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD11_RS31375 b12ebee2b008a8ab8f1586aa1085c715 310 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 164 1.1E-46 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD11_RS31375 b12ebee2b008a8ab8f1586aa1085c715 310 SUPERFAMILY SSF48179 166 296 2.27E-35 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS31375 b12ebee2b008a8ab8f1586aa1085c715 310 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 9 22 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD11_RS31375 b12ebee2b008a8ab8f1586aa1085c715 310 SUPERFAMILY SSF51735 6 164 4.27E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS31375 b12ebee2b008a8ab8f1586aa1085c715 310 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 167 293 2.3E-35 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 SMD11_RS31375 b12ebee2b008a8ab8f1586aa1085c715 310 Gene3D G3DSA:1.10.1040.10 166 297 6.1E-40 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS31375 b12ebee2b008a8ab8f1586aa1085c715 310 Gene3D G3DSA:3.40.50.720 6 164 2.7E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS13990 335c9172530bb7e193bb994196e56766 166 Pfam PF01613 Flavin reductase like domain 11 165 2.6E-39 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS13990 335c9172530bb7e193bb994196e56766 166 SUPERFAMILY SSF50475 2 165 1.08E-42 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS13990 335c9172530bb7e193bb994196e56766 166 SMART SM00903 10 164 2.2E-49 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS13990 335c9172530bb7e193bb994196e56766 166 Gene3D G3DSA:2.30.110.10 5 166 1.9E-51 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS01510 ce38bfef5414d1dd68354812c04fb047 826 Pfam PF13560 Helix-turn-helix domain 1 50 7.5E-9 T 06-07-2017 SMD11_RS01510 ce38bfef5414d1dd68354812c04fb047 826 Pfam PF05729 NACHT domain 228 348 3.3E-6 T 06-07-2017 SMD11_RS01510 ce38bfef5414d1dd68354812c04fb047 826 Gene3D G3DSA:1.10.260.40 1 46 2.6E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS01510 ce38bfef5414d1dd68354812c04fb047 826 SUPERFAMILY SSF52540 213 388 4.56E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01510 ce38bfef5414d1dd68354812c04fb047 826 SUPERFAMILY SSF47413 1 46 3.85E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS01510 ce38bfef5414d1dd68354812c04fb047 826 SMART SM00530 1 47 0.0072 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS22510 02195fca79db8f9974c028ddfd5811b8 144 SUPERFAMILY SSF81301 7 118 2.62E-35 T 06-07-2017 SMD11_RS22510 02195fca79db8f9974c028ddfd5811b8 144 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 11 109 4.3E-29 T 06-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS SMD11_RS22510 02195fca79db8f9974c028ddfd5811b8 144 Pfam PF02410 Ribosomal silencing factor during starvation 14 109 7.1E-22 T 06-07-2017 SMD11_RS22510 02195fca79db8f9974c028ddfd5811b8 144 Gene3D G3DSA:3.30.460.10 7 113 2.0E-32 T 06-07-2017 SMD11_RS22510 02195fca79db8f9974c028ddfd5811b8 144 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 7 110 22.69 T 06-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS SMD11_RS11625 528914eaced8dd80dc5ca2f4f0d6392e 261 Gene3D G3DSA:3.40.190.10 41 167 6.1E-34 T 06-07-2017 SMD11_RS11625 528914eaced8dd80dc5ca2f4f0d6392e 261 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 49 255 2.1E-39 T 06-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 SMD11_RS11625 528914eaced8dd80dc5ca2f4f0d6392e 261 SUPERFAMILY SSF53850 43 260 1.92E-51 T 06-07-2017 SMD11_RS11625 528914eaced8dd80dc5ca2f4f0d6392e 261 PIRSF PIRSF004846 3 261 9.7E-64 T 06-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 SMD11_RS11625 528914eaced8dd80dc5ca2f4f0d6392e 261 Pfam PF13531 Bacterial extracellular solute-binding protein 44 259 4.8E-43 T 06-07-2017 SMD11_RS11625 528914eaced8dd80dc5ca2f4f0d6392e 261 Gene3D G3DSA:3.40.190.10 179 250 1.8E-7 T 06-07-2017 SMD11_RS06855 801083fcb2c07410a4066bbe5913fe36 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 72 1.2E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS06855 801083fcb2c07410a4066bbe5913fe36 239 SMART SM00866 92 230 2.2E-36 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS06855 801083fcb2c07410a4066bbe5913fe36 239 Gene3D G3DSA:1.10.10.10 2 73 5.5E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06855 801083fcb2c07410a4066bbe5913fe36 239 Pfam PF07702 UTRA domain 93 229 3.0E-39 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS06855 801083fcb2c07410a4066bbe5913fe36 239 Gene3D G3DSA:3.40.1410.10 74 232 2.2E-49 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS06855 801083fcb2c07410a4066bbe5913fe36 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 1.2E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS06855 801083fcb2c07410a4066bbe5913fe36 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 1.2E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS06855 801083fcb2c07410a4066bbe5913fe36 239 SMART SM00345 13 72 8.5E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS06855 801083fcb2c07410a4066bbe5913fe36 239 SUPERFAMILY SSF64288 60 234 4.4E-47 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS06855 801083fcb2c07410a4066bbe5913fe36 239 SUPERFAMILY SSF46785 2 76 4.61E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17855 f9d327c20fe167aa3d8312e7851b5d17 233 Pfam PF00072 Response regulator receiver domain 9 118 8.3E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS17855 f9d327c20fe167aa3d8312e7851b5d17 233 SMART SM00862 155 230 8.9E-29 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS17855 f9d327c20fe167aa3d8312e7851b5d17 233 SMART SM00448 7 118 5.6E-39 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS17855 f9d327c20fe167aa3d8312e7851b5d17 233 SUPERFAMILY SSF46894 132 231 1.84E-30 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS17855 f9d327c20fe167aa3d8312e7851b5d17 233 Gene3D G3DSA:1.10.10.10 133 232 1.6E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17855 f9d327c20fe167aa3d8312e7851b5d17 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 230 3.6E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS17855 f9d327c20fe167aa3d8312e7851b5d17 233 Gene3D G3DSA:3.40.50.2300 4 132 3.5E-40 T 06-07-2017 SMD11_RS17855 f9d327c20fe167aa3d8312e7851b5d17 233 SUPERFAMILY SSF52172 4 133 2.56E-41 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS07305 6551adc44804c1ad8f34ade32ed57d84 580 SMART SM00642 98 445 1.2E-7 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS07305 6551adc44804c1ad8f34ade32ed57d84 580 Gene3D G3DSA:3.20.20.80 469 503 4.3E-79 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS07305 6551adc44804c1ad8f34ade32ed57d84 580 Gene3D G3DSA:3.20.20.80 92 431 4.3E-79 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS07305 6551adc44804c1ad8f34ade32ed57d84 580 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 3 532 6.2E-220 T 06-07-2017 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902 SMD11_RS07305 6551adc44804c1ad8f34ade32ed57d84 580 Pfam PF00128 Alpha amylase, catalytic domain 114 189 1.9E-8 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS07305 6551adc44804c1ad8f34ade32ed57d84 580 SUPERFAMILY SSF51445 74 506 1.52E-107 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS07305 6551adc44804c1ad8f34ade32ed57d84 580 SUPERFAMILY SSF81296 2 77 2.0E-15 T 06-07-2017 IPR014756 Immunoglobulin E-set SMD11_RS07305 6551adc44804c1ad8f34ade32ed57d84 580 Pfam PF11941 Domain of unknown function (DUF3459) 489 577 3.4E-9 T 06-07-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) SMD11_RS07305 6551adc44804c1ad8f34ade32ed57d84 580 Gene3D G3DSA:2.60.40.10 2 77 3.4E-23 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS07305 6551adc44804c1ad8f34ade32ed57d84 580 PIRSF PIRSF006337 1 576 1.2E-219 T 06-07-2017 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902 SMD11_RS21060 8bc32eadf5e409e5bfe96665de26d536 766 Gene3D G3DSA:3.30.365.10 634 759 1.1E-42 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS21060 8bc32eadf5e409e5bfe96665de26d536 766 Gene3D G3DSA:3.30.365.10 363 466 1.1E-42 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS21060 8bc32eadf5e409e5bfe96665de26d536 766 Gene3D G3DSA:3.30.365.10 193 283 1.2E-20 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS21060 8bc32eadf5e409e5bfe96665de26d536 766 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 37 141 3.2E-28 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS21060 8bc32eadf5e409e5bfe96665de26d536 766 Gene3D G3DSA:3.90.1170.50 20 130 1.5E-38 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS21060 8bc32eadf5e409e5bfe96665de26d536 766 SUPERFAMILY SSF54665 20 143 1.06E-37 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS21060 8bc32eadf5e409e5bfe96665de26d536 766 Gene3D G3DSA:3.30.365.10 286 360 4.6E-30 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS21060 8bc32eadf5e409e5bfe96665de26d536 766 Gene3D G3DSA:3.30.365.10 131 190 4.6E-30 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS21060 8bc32eadf5e409e5bfe96665de26d536 766 Gene3D G3DSA:3.30.365.10 476 633 1.4E-22 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS21060 8bc32eadf5e409e5bfe96665de26d536 766 SMART SM01008 36 142 7.6E-42 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS21060 8bc32eadf5e409e5bfe96665de26d536 766 SUPERFAMILY SSF56003 143 759 2.22E-123 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS21060 8bc32eadf5e409e5bfe96665de26d536 766 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 177 705 2.2E-111 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS00125 0045395467e17edcff100eb3d8f4230a 301 Pfam PF03572 Peptidase family S41 135 281 1.1E-20 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMD11_RS00125 0045395467e17edcff100eb3d8f4230a 301 Gene3D G3DSA:3.30.750.44 12 78 7.4E-8 T 06-07-2017 SMD11_RS00125 0045395467e17edcff100eb3d8f4230a 301 Gene3D G3DSA:3.90.226.10 108 294 1.5E-32 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS00125 0045395467e17edcff100eb3d8f4230a 301 SMART SM00245 80 283 1.3E-14 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMD11_RS00125 0045395467e17edcff100eb3d8f4230a 301 SUPERFAMILY SSF52096 18 298 2.98E-42 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS00125 0045395467e17edcff100eb3d8f4230a 301 Pfam PF11918 N-terminal domain of Peptidase_S41 in eukaryotic IRBP 12 79 3.8E-11 T 06-07-2017 SMD11_RS19255 464fd602490cbc55686f90237a032c3e 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 195 4.8E-22 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19255 464fd602490cbc55686f90237a032c3e 200 Gene3D G3DSA:1.10.10.10 141 198 8.6E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19255 464fd602490cbc55686f90237a032c3e 200 Pfam PF04545 Sigma-70, region 4 147 196 1.8E-11 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19255 464fd602490cbc55686f90237a032c3e 200 SUPERFAMILY SSF88659 125 198 2.24E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19255 464fd602490cbc55686f90237a032c3e 200 Gene3D G3DSA:1.10.1740.10 19 134 8.2E-15 T 06-07-2017 SMD11_RS19255 464fd602490cbc55686f90237a032c3e 200 Pfam PF04542 Sigma-70 region 2 39 107 3.2E-9 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19255 464fd602490cbc55686f90237a032c3e 200 SUPERFAMILY SSF88946 17 124 5.49E-15 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS25565 eefb6dc5b43e57fe05e05e510ac034d3 234 SUPERFAMILY SSF51735 3 230 5.83E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS25565 eefb6dc5b43e57fe05e05e510ac034d3 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 6.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS25565 eefb6dc5b43e57fe05e05e510ac034d3 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 6.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS25565 eefb6dc5b43e57fe05e05e510ac034d3 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 6.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS25565 eefb6dc5b43e57fe05e05e510ac034d3 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS25565 eefb6dc5b43e57fe05e05e510ac034d3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.7E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS25565 eefb6dc5b43e57fe05e05e510ac034d3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 4.7E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS25565 eefb6dc5b43e57fe05e05e510ac034d3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 4.7E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS25565 eefb6dc5b43e57fe05e05e510ac034d3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 4.7E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS25565 eefb6dc5b43e57fe05e05e510ac034d3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 4.7E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS25565 eefb6dc5b43e57fe05e05e510ac034d3 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 4.7E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS25565 eefb6dc5b43e57fe05e05e510ac034d3 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 230 2.6E-63 T 06-07-2017 SMD11_RS25565 eefb6dc5b43e57fe05e05e510ac034d3 234 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 5 230 1.0E-94 T 06-07-2017 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 SMD11_RS25565 eefb6dc5b43e57fe05e05e510ac034d3 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 176 4.9E-9 T 06-07-2017 SMD11_RS25565 eefb6dc5b43e57fe05e05e510ac034d3 234 Gene3D G3DSA:3.40.50.720 3 230 3.2E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Gene3D G3DSA:3.90.1150.10 101 175 1.2E-29 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Gene3D G3DSA:3.90.1150.10 437 525 1.2E-29 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2094 2109 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 SUPERFAMILY SSF52777 2151 2348 9.64E-38 T 06-07-2017 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 SMART SM00823 Phosphopantetheine attachment site 2068 2139 1.1E-13 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 SUPERFAMILY SSF52777 1073 1245 3.89E-48 T 06-07-2017 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Pfam PF00501 AMP-binding enzyme 1538 1932 1.7E-82 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1681 1692 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Gene3D G3DSA:3.40.50.980 1704 1844 1.4E-28 T 06-07-2017 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Gene3D G3DSA:3.40.50.980 1531 1703 4.1E-38 T 06-07-2017 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 SMART SM01294 2069 2135 3.1E-4 T 06-07-2017 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Gene3D G3DSA:3.40.640.10 177 433 3.5E-63 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Pfam PF00550 Phosphopantetheine attachment site 2069 2135 5.5E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Gene3D G3DSA:1.10.1200.10 2068 2139 2.6E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 SUPERFAMILY SSF52777 1259 1499 3.89E-56 T 06-07-2017 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 SUPERFAMILY SSF51679 715 1047 1.31E-69 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Gene3D G3DSA:2.30.38.10 1845 1921 4.2E-27 T 06-07-2017 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 SUPERFAMILY SSF53383 108 526 1.11E-85 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Pfam PF13745 HxxPF-repeated domain 2496 2558 6.5E-9 T 06-07-2017 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Pfam PF13745 HxxPF-repeated domain 1390 1480 4.6E-25 T 06-07-2017 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Pfam PF00668 Condensation domain 2153 2445 6.1E-42 T 06-07-2017 IPR001242 Condensation domain SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Pfam PF00668 Condensation domain 1069 1368 3.3E-66 T 06-07-2017 IPR001242 Condensation domain SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Pfam PF13193 AMP-binding enzyme C-terminal domain 1940 2022 6.3E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Gene3D G3DSA:3.30.300.30 1926 2031 5.5E-28 T 06-07-2017 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1558 1956 2.1E-119 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Gene3D G3DSA:3.20.20.30 711 1048 3.1E-75 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 TIGRFAM TIGR04020 seco_metab_LLM: natural product biosynthesis luciferase-like monooxygenase domain 715 1056 6.3E-133 T 06-07-2017 IPR024011 Natural product biosynthesis luciferase-like monooxygenase domain SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 SUPERFAMILY SSF52777 2335 2568 8.12E-34 T 06-07-2017 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 SUPERFAMILY SSF47336 2068 2142 7.46E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Pfam PF00202 Aminotransferase class-III 140 497 6.7E-51 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 Pfam PF00296 Luciferase-like monooxygenase 728 1032 6.5E-51 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS28525 23d0172b15a29996a915dddbb0f846e3 2576 SUPERFAMILY SSF56801 1527 2031 1.31E-129 T 06-07-2017 SMD11_RS31110 ac58381a1b482acb9b7a65e5de09712c 355 Gene3D G3DSA:3.20.20.80 49 345 1.1E-38 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS31110 ac58381a1b482acb9b7a65e5de09712c 355 SUPERFAMILY SSF51445 48 346 4.82E-41 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS31110 ac58381a1b482acb9b7a65e5de09712c 355 ProSitePatterns PS01095 Chitinases family 18 active site. 163 171 - T 06-07-2017 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 SMD11_RS31110 ac58381a1b482acb9b7a65e5de09712c 355 Pfam PF00704 Glycosyl hydrolases family 18 51 338 2.7E-19 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 SMD11_RS31110 ac58381a1b482acb9b7a65e5de09712c 355 SMART SM00636 49 338 0.0026 T 06-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 SMD11_RS31865 5a87ca3d0853222b0217daafc66581e1 202 Gene3D G3DSA:3.30.450.40 64 131 2.2E-6 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS31865 5a87ca3d0853222b0217daafc66581e1 202 SUPERFAMILY SSF55781 65 193 2.55E-6 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS31865 5a87ca3d0853222b0217daafc66581e1 202 Gene3D G3DSA:1.10.10.10 6 44 8.5E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20775 b52d21faaa38084b74b12c33025615df 383 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 16 371 35.132 T 06-07-2017 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 SMD11_RS20775 b52d21faaa38084b74b12c33025615df 383 Gene3D G3DSA:1.20.120.420 20 172 1.2E-38 T 06-07-2017 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 SMD11_RS20775 b52d21faaa38084b74b12c33025615df 383 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 48 361 5.5E-81 T 06-07-2017 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 SMD11_RS20775 b52d21faaa38084b74b12c33025615df 383 Pfam PF01008 Initiation factor 2 subunit family 63 361 5.0E-57 T 06-07-2017 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 SMD11_RS20775 b52d21faaa38084b74b12c33025615df 383 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 29 360 4.2E-104 T 06-07-2017 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 SMD11_RS20775 b52d21faaa38084b74b12c33025615df 383 Gene3D G3DSA:3.40.50.10470 173 362 7.7E-55 T 06-07-2017 SMD11_RS20775 b52d21faaa38084b74b12c33025615df 383 SUPERFAMILY SSF100950 27 361 3.1E-92 T 06-07-2017 SMD11_RS05045 8e4e0f6a95917f8ca086a35b6c7f3e96 175 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 10 157 1.9E-30 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 SMD11_RS05045 8e4e0f6a95917f8ca086a35b6c7f3e96 175 Pfam PF01750 Hydrogenase maturation protease 55 155 3.1E-8 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 SMD11_RS05045 8e4e0f6a95917f8ca086a35b6c7f3e96 175 SUPERFAMILY SSF53163 7 158 4.71E-31 T 06-07-2017 IPR023430 Peptidase HybD-like domain SMD11_RS05045 8e4e0f6a95917f8ca086a35b6c7f3e96 175 Gene3D G3DSA:3.40.50.1450 7 160 7.6E-32 T 06-07-2017 IPR023430 Peptidase HybD-like domain SMD11_RS04445 972b8677003e682da00294570e68a19d 633 Pfam PF00005 ABC transporter 368 522 7.7E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS04445 972b8677003e682da00294570e68a19d 633 SMART SM00382 377 569 3.7E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS04445 972b8677003e682da00294570e68a19d 633 SUPERFAMILY SSF52540 346 594 3.32E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04445 972b8677003e682da00294570e68a19d 633 Gene3D G3DSA:1.20.1560.10 23 317 3.0E-16 T 06-07-2017 SMD11_RS04445 972b8677003e682da00294570e68a19d 633 Gene3D G3DSA:3.40.50.300 351 585 9.4E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04445 972b8677003e682da00294570e68a19d 633 SUPERFAMILY SSF90123 25 315 1.57E-18 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS29265 b9f8a98291dcecccab53d73221708b1e 152 Gene3D G3DSA:3.40.50.620 5 151 8.6E-34 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS29265 b9f8a98291dcecccab53d73221708b1e 152 PRINTS PR01438 Universal stress protein signature 107 119 4.9E-15 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS29265 b9f8a98291dcecccab53d73221708b1e 152 PRINTS PR01438 Universal stress protein signature 125 147 4.9E-15 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS29265 b9f8a98291dcecccab53d73221708b1e 152 PRINTS PR01438 Universal stress protein signature 5 23 4.9E-15 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS29265 b9f8a98291dcecccab53d73221708b1e 152 Pfam PF00582 Universal stress protein family 6 147 1.7E-25 T 06-07-2017 IPR006016 UspA GO:0006950 SMD11_RS29265 b9f8a98291dcecccab53d73221708b1e 152 SUPERFAMILY SSF52402 6 150 3.52E-29 T 06-07-2017 SMD11_RS32300 2dcce7f53384e660783be0c4783f5d2d 250 SUPERFAMILY SSF55961 101 245 2.24E-41 T 06-07-2017 SMD11_RS32300 2dcce7f53384e660783be0c4783f5d2d 250 Pfam PF12840 Helix-turn-helix domain 2 62 2.7E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32300 2dcce7f53384e660783be0c4783f5d2d 250 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 117 239 1.4E-25 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMD11_RS32300 2dcce7f53384e660783be0c4783f5d2d 250 Gene3D G3DSA:3.30.530.20 101 244 2.1E-37 T 06-07-2017 IPR023393 START-like domain SMD11_RS32300 2dcce7f53384e660783be0c4783f5d2d 250 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 3.1E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS32300 2dcce7f53384e660783be0c4783f5d2d 250 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 3.1E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS32300 2dcce7f53384e660783be0c4783f5d2d 250 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 3.1E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS32300 2dcce7f53384e660783be0c4783f5d2d 250 SUPERFAMILY SSF46785 1 116 1.07E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32300 2dcce7f53384e660783be0c4783f5d2d 250 Gene3D G3DSA:1.10.10.10 1 100 1.5E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32300 2dcce7f53384e660783be0c4783f5d2d 250 SMART SM00418 3 85 1.9E-15 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS24760 2d7cb2fd413a4acb1ef9a2fccb186466 414 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 93 107 - T 06-07-2017 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD11_RS24760 2d7cb2fd413a4acb1ef9a2fccb186466 414 Gene3D G3DSA:3.40.50.1100 190 404 6.4E-97 T 06-07-2017 SMD11_RS24760 2d7cb2fd413a4acb1ef9a2fccb186466 414 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 19 401 5.4E-184 T 06-07-2017 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD11_RS24760 2d7cb2fd413a4acb1ef9a2fccb186466 414 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 14 403 51.764 T 06-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD11_RS24760 2d7cb2fd413a4acb1ef9a2fccb186466 414 PIRSF PIRSF001413 8 407 5.8E-159 T 06-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD11_RS24760 2d7cb2fd413a4acb1ef9a2fccb186466 414 Gene3D G3DSA:3.40.50.1100 111 189 8.9E-23 T 06-07-2017 SMD11_RS24760 2d7cb2fd413a4acb1ef9a2fccb186466 414 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 64 390 3.4E-51 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS24760 2d7cb2fd413a4acb1ef9a2fccb186466 414 SUPERFAMILY SSF53686 15 402 1.22E-145 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS25050 43bb88e0b7f1850727c99821ff1a62e5 431 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS25050 43bb88e0b7f1850727c99821ff1a62e5 431 Pfam PF07690 Major Facilitator Superfamily 38 355 3.5E-31 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS25050 43bb88e0b7f1850727c99821ff1a62e5 431 Gene3D G3DSA:1.20.1250.20 22 210 1.7E-23 T 06-07-2017 SMD11_RS25050 43bb88e0b7f1850727c99821ff1a62e5 431 Gene3D G3DSA:1.20.1250.20 228 415 1.6E-22 T 06-07-2017 SMD11_RS25050 43bb88e0b7f1850727c99821ff1a62e5 431 SUPERFAMILY SSF103473 3 415 1.11E-60 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS06425 db035a542c1e5073d833027d0cf228e7 435 SUPERFAMILY SSF53383 54 429 2.42E-107 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS06425 db035a542c1e5073d833027d0cf228e7 435 Gene3D G3DSA:3.90.1150.10 318 432 1.6E-32 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS06425 db035a542c1e5073d833027d0cf228e7 435 Gene3D G3DSA:3.40.640.10 86 317 4.8E-79 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS06425 db035a542c1e5073d833027d0cf228e7 435 Pfam PF00202 Aminotransferase class-III 55 425 4.6E-93 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS06425 db035a542c1e5073d833027d0cf228e7 435 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 246 283 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS23665 369460a6ead6dee684cd79ffe47b064f 467 Pfam PF04213 Htaa 237 386 1.0E-43 T 06-07-2017 IPR007331 Htaa SMD11_RS23665 369460a6ead6dee684cd79ffe47b064f 467 Pfam PF04213 Htaa 38 203 5.4E-54 T 06-07-2017 IPR007331 Htaa SMD11_RS21255 10f22a391139dbe3c62e3bbaafcce959 243 Pfam PF03725 3' exoribonuclease family, domain 2 162 225 9.9E-11 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD11_RS21255 10f22a391139dbe3c62e3bbaafcce959 243 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 06-07-2017 IPR018336 Ribonuclease PH, conserved site SMD11_RS21255 10f22a391139dbe3c62e3bbaafcce959 243 Pfam PF01138 3' exoribonuclease family, domain 1 11 141 4.6E-25 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD11_RS21255 10f22a391139dbe3c62e3bbaafcce959 243 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 239 1.2E-115 T 06-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 SMD11_RS21255 10f22a391139dbe3c62e3bbaafcce959 243 SUPERFAMILY SSF54211 3 183 2.83E-47 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS21255 10f22a391139dbe3c62e3bbaafcce959 243 Gene3D G3DSA:3.30.230.70 3 240 9.3E-32 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD11_RS21255 10f22a391139dbe3c62e3bbaafcce959 243 Hamap MF_00564 Ribonuclease PH [rph]. 2 240 47.632 T 06-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 SMD11_RS21255 10f22a391139dbe3c62e3bbaafcce959 243 SUPERFAMILY SSF55666 156 240 3.93E-24 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SMD11_RS24300 523c387c48cd4e89f2223870436ae751 150 Gene3D G3DSA:3.30.530.20 4 145 7.3E-19 T 06-07-2017 IPR023393 START-like domain SMD11_RS24300 523c387c48cd4e89f2223870436ae751 150 SUPERFAMILY SSF55961 1 147 7.25E-31 T 06-07-2017 SMD11_RS24300 523c387c48cd4e89f2223870436ae751 150 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 144 6.9E-18 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase SMD11_RS12995 d28daa73e2f111bab74ebc7dd5626180 266 SUPERFAMILY SSF54637 122 263 1.49E-7 T 06-07-2017 IPR029069 HotDog domain SMD11_RS12995 d28daa73e2f111bab74ebc7dd5626180 266 SUPERFAMILY SSF54637 48 129 4.23E-6 T 06-07-2017 IPR029069 HotDog domain SMD11_RS12995 d28daa73e2f111bab74ebc7dd5626180 266 Pfam PF13622 Thioesterase-like superfamily 28 263 5.4E-33 T 06-07-2017 SMD11_RS10530 cd4ca49ae108554d617c05f1cd476333 208 SUPERFAMILY SSF51735 6 207 1.56E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10530 cd4ca49ae108554d617c05f1cd476333 208 Pfam PF13460 NAD(P)H-binding 11 193 1.9E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10530 cd4ca49ae108554d617c05f1cd476333 208 Gene3D G3DSA:3.40.50.720 6 208 8.8E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS14435 abbbd242c0c02e44850c557bf921b6e5 257 SMART SM00382 27 211 7.1E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS14435 abbbd242c0c02e44850c557bf921b6e5 257 Gene3D G3DSA:3.40.50.300 4 227 2.6E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14435 abbbd242c0c02e44850c557bf921b6e5 257 Pfam PF00005 ABC transporter 19 167 3.1E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS14435 abbbd242c0c02e44850c557bf921b6e5 257 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS14435 abbbd242c0c02e44850c557bf921b6e5 257 SUPERFAMILY SSF52540 3 225 5.74E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00800 b0aadafb6450309c420c328f87451ced 457 SUPERFAMILY SSF53383 27 450 5.82E-116 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS00800 b0aadafb6450309c420c328f87451ced 457 Pfam PF00202 Aminotransferase class-III 35 449 7.9E-93 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS00800 b0aadafb6450309c420c328f87451ced 457 Gene3D G3DSA:3.40.640.10 75 323 1.3E-67 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS00800 b0aadafb6450309c420c328f87451ced 457 Gene3D G3DSA:3.90.1150.10 324 451 3.1E-49 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS00800 b0aadafb6450309c420c328f87451ced 457 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 18 454 2.9E-151 T 06-07-2017 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 SMD11_RS00800 b0aadafb6450309c420c328f87451ced 457 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 259 296 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS05620 7df9515b60a2293f7a2f883511a62d43 345 SUPERFAMILY SSF51679 9 332 1.7E-64 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS05620 7df9515b60a2293f7a2f883511a62d43 345 Pfam PF00296 Luciferase-like monooxygenase 12 311 1.6E-72 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS05620 7df9515b60a2293f7a2f883511a62d43 345 Gene3D G3DSA:3.20.20.30 13 336 1.5E-68 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS28735 497bb90447d2959def584f2f70839531 480 Pfam PF00206 Lyase 56 303 1.2E-18 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal SMD11_RS28735 497bb90447d2959def584f2f70839531 480 Pfam PF10397 Adenylosuccinate lyase C-terminus 373 457 3.0E-11 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS28735 497bb90447d2959def584f2f70839531 480 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 14 458 1.3E-125 T 06-07-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS28735 497bb90447d2959def584f2f70839531 480 SUPERFAMILY SSF48557 13 459 3.61E-79 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 SMD11_RS28735 497bb90447d2959def584f2f70839531 480 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 6.4E-11 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS28735 497bb90447d2959def584f2f70839531 480 PRINTS PR00149 Fumarate lyase superfamily signature 101 119 6.4E-11 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS28735 497bb90447d2959def584f2f70839531 480 PRINTS PR00149 Fumarate lyase superfamily signature 146 164 6.4E-11 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS28735 497bb90447d2959def584f2f70839531 480 PRINTS PR00149 Fumarate lyase superfamily signature 283 299 6.4E-11 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS28735 497bb90447d2959def584f2f70839531 480 Gene3D G3DSA:1.10.275.10 16 104 3.0E-23 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal SMD11_RS28735 497bb90447d2959def584f2f70839531 480 Gene3D G3DSA:1.20.200.10 105 455 5.1E-79 T 06-07-2017 SMD11_RS28735 497bb90447d2959def584f2f70839531 480 SMART SM00998 372 458 6.6E-19 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS28735 497bb90447d2959def584f2f70839531 480 ProSitePatterns PS00163 Fumarate lyases signature. 283 292 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 SMART SM00091 6 73 0.46 T 06-07-2017 IPR000014 PAS domain SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 SMART SM00091 127 193 1.2E-5 T 06-07-2017 IPR000014 PAS domain SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 Gene3D G3DSA:3.30.450.40 255 432 3.5E-33 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 SUPERFAMILY SSF55874 717 790 3.8E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 Pfam PF08448 PAS fold 133 246 4.0E-21 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 SMART SM00065 266 434 0.0059 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 Pfam PF01590 GAF domain 317 424 4.2E-9 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 SUPERFAMILY SSF55785 126 242 1.0E-15 T 06-07-2017 IPR000014 PAS domain SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 482 677 3.0E-48 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 SUPERFAMILY SSF55785 15 108 5.31E-9 T 06-07-2017 IPR000014 PAS domain SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 Pfam PF13581 Histidine kinase-like ATPase domain 691 799 2.2E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 Gene3D G3DSA:3.30.450.20 16 108 7.7E-8 T 06-07-2017 SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 Pfam PF00989 PAS fold 17 79 1.0E-5 T 06-07-2017 IPR013767 PAS fold GO:0006355 SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 SMART SM00331 457 677 5.4E-35 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 Gene3D G3DSA:3.30.450.20 123 244 3.9E-20 T 06-07-2017 SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 SUPERFAMILY SSF55781 334 434 2.03E-14 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 SUPERFAMILY SSF81606 463 676 1.28E-6 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS00430 70dcef4ff8b07ea0167881f6d0e3b90c 805 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 128 250 9.7E-13 T 06-07-2017 IPR000014 PAS domain SMD11_RS29895 3a4d99676a2c59510e77242eb3d891ca 364 SUPERFAMILY SSF48576 56 360 1.73E-72 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS29895 3a4d99676a2c59510e77242eb3d891ca 364 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 113 127 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 SMD11_RS29895 3a4d99676a2c59510e77242eb3d891ca 364 Pfam PF00348 Polyprenyl synthetase 63 306 1.5E-52 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 SMD11_RS29895 3a4d99676a2c59510e77242eb3d891ca 364 Gene3D G3DSA:1.10.600.10 51 361 1.8E-81 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 126 3.9E-53 T 06-07-2017 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 SUPERFAMILY SSF51338 2 183 2.47E-56 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 ProSitePatterns PS01120 Urease nickel ligands signature. 134 147 - T 06-07-2017 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 Gene3D G3DSA:3.20.20.140 151 435 2.1E-193 T 06-07-2017 SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 Gene3D G3DSA:3.20.20.140 494 571 2.1E-193 T 06-07-2017 SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 Gene3D G3DSA:2.30.40.10 72 150 1.5E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 SUPERFAMILY SSF51338 415 485 1.39E-9 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 Pfam PF01979 Amidohydrolase family 132 456 9.3E-70 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 407 422 1.5E-32 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 433 446 1.5E-32 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 341 357 1.5E-32 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 302 319 1.5E-32 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 Hamap MF_01953 Urease subunit alpha [ureC]. 2 573 55.629 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 SUPERFAMILY SSF51556 136 438 8.82E-187 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 SUPERFAMILY SSF51556 487 573 8.82E-187 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 ProSitePatterns PS00145 Urease active site. 324 340 - T 06-07-2017 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28815 1fc838ad4b8f47271746032201230cb5 573 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 573 1.2E-267 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS12110 701a6b082194ebf74adbe3f51d18f2de 362 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 362 5.7E-133 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 SMD11_RS12110 701a6b082194ebf74adbe3f51d18f2de 362 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 362 42.078 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 SMD11_RS12110 701a6b082194ebf74adbe3f51d18f2de 362 PIRSF PIRSF006641 1 362 3.7E-141 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 SMD11_RS12110 701a6b082194ebf74adbe3f51d18f2de 362 SUPERFAMILY SSF81271 278 362 1.02E-34 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SMD11_RS12110 701a6b082194ebf74adbe3f51d18f2de 362 Gene3D G3DSA:3.10.20.30 261 362 2.2E-44 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS12110 701a6b082194ebf74adbe3f51d18f2de 362 Pfam PF01926 50S ribosome-binding GTPase 5 122 1.2E-22 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS12110 701a6b082194ebf74adbe3f51d18f2de 362 Pfam PF06071 Protein of unknown function (DUF933) 278 361 1.7E-38 T 06-07-2017 IPR013029 Domain of unknown function DUF933 SMD11_RS12110 701a6b082194ebf74adbe3f51d18f2de 362 Gene3D G3DSA:1.10.150.300 132 201 2.6E-19 T 06-07-2017 IPR023192 TGS-like domain SMD11_RS12110 701a6b082194ebf74adbe3f51d18f2de 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.2E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS12110 701a6b082194ebf74adbe3f51d18f2de 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 3.2E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS12110 701a6b082194ebf74adbe3f51d18f2de 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 3.2E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS12110 701a6b082194ebf74adbe3f51d18f2de 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 3.2E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS12110 701a6b082194ebf74adbe3f51d18f2de 362 Gene3D G3DSA:3.40.50.300 202 260 5.5E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12110 701a6b082194ebf74adbe3f51d18f2de 362 Gene3D G3DSA:3.40.50.300 3 131 5.5E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12110 701a6b082194ebf74adbe3f51d18f2de 362 SUPERFAMILY SSF52540 3 300 6.16E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS32765 eb67144432c3606c57c8b738d944062b 185 SUPERFAMILY SSF46785 3 180 8.09E-39 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32765 eb67144432c3606c57c8b738d944062b 185 Pfam PF10400 Virulence activator alpha C-term 92 178 2.6E-22 T 06-07-2017 IPR018309 Transcription regulator PadR, C-terminal SMD11_RS32765 eb67144432c3606c57c8b738d944062b 185 Pfam PF03551 Transcriptional regulator PadR-like family 7 79 2.5E-12 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal SMD11_RS32765 eb67144432c3606c57c8b738d944062b 185 Gene3D G3DSA:1.10.10.10 1 87 5.0E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS24965 d120230a6a8c2229629bcf11bdc354a7 962 SUPERFAMILY SSF52540 21 174 4.57E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24965 d120230a6a8c2229629bcf11bdc354a7 962 SUPERFAMILY SSF52540 201 359 4.57E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24965 d120230a6a8c2229629bcf11bdc354a7 962 Pfam PF00271 Helicase conserved C-terminal domain 229 347 3.0E-10 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS24965 d120230a6a8c2229629bcf11bdc354a7 962 Gene3D G3DSA:3.40.50.300 9 173 1.0E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24965 d120230a6a8c2229629bcf11bdc354a7 962 SMART SM00847 409 502 2.5E-13 T 06-07-2017 IPR007502 Helicase-associated domain GO:0004386 SMD11_RS24965 d120230a6a8c2229629bcf11bdc354a7 962 Gene3D G3DSA:3.40.50.300 224 363 1.3E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24965 d120230a6a8c2229629bcf11bdc354a7 962 Pfam PF04408 Helicase associated domain (HA2) 410 481 6.6E-9 T 06-07-2017 IPR007502 Helicase-associated domain GO:0004386 SMD11_RS24965 d120230a6a8c2229629bcf11bdc354a7 962 Pfam PF08482 ATP-dependent helicase C-terminal 816 949 4.2E-50 T 06-07-2017 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal SMD11_RS24965 d120230a6a8c2229629bcf11bdc354a7 962 SMART SM00487 8 198 7.7E-18 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS24965 d120230a6a8c2229629bcf11bdc354a7 962 SMART SM00490 248 349 2.2E-10 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS22530 d04c3167a29f089d8fe8f1d88f3d5025 602 ProSitePatterns PS00079 Multicopper oxidases signature 1. 556 576 - T 06-07-2017 IPR033138 Multicopper oxidases, conserved site SMD11_RS22530 d04c3167a29f089d8fe8f1d88f3d5025 602 SUPERFAMILY SSF49503 206 319 1.85E-30 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS22530 d04c3167a29f089d8fe8f1d88f3d5025 602 SUPERFAMILY SSF49503 531 582 1.85E-30 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS22530 d04c3167a29f089d8fe8f1d88f3d5025 602 Gene3D G3DSA:2.60.40.420 136 204 6.2E-26 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS22530 d04c3167a29f089d8fe8f1d88f3d5025 602 Gene3D G3DSA:2.60.40.420 38 97 6.2E-26 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS22530 d04c3167a29f089d8fe8f1d88f3d5025 602 SUPERFAMILY SSF49503 416 499 2.44E-14 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS22530 d04c3167a29f089d8fe8f1d88f3d5025 602 SUPERFAMILY SSF49503 528 578 2.44E-14 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS22530 d04c3167a29f089d8fe8f1d88f3d5025 602 ProSitePatterns PS00080 Multicopper oxidases signature 2. 561 572 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 SMD11_RS22530 d04c3167a29f089d8fe8f1d88f3d5025 602 Pfam PF07731 Multicopper oxidase 454 581 1.5E-25 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 SMD11_RS22530 d04c3167a29f089d8fe8f1d88f3d5025 602 SUPERFAMILY SSF49503 22 202 2.7E-22 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS22530 d04c3167a29f089d8fe8f1d88f3d5025 602 Pfam PF07732 Multicopper oxidase 135 201 3.0E-6 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 SMD11_RS22530 d04c3167a29f089d8fe8f1d88f3d5025 602 Pfam PF07732 Multicopper oxidase 60 93 6.5E-5 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 SMD11_RS22530 d04c3167a29f089d8fe8f1d88f3d5025 602 Gene3D G3DSA:2.60.40.420 205 343 2.1E-25 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS22530 d04c3167a29f089d8fe8f1d88f3d5025 602 Gene3D G3DSA:2.60.40.420 457 580 4.0E-30 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS04030 658b2dc8a4b1d914a34cd998de97d97f 517 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 429 3.9E-72 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain SMD11_RS04030 658b2dc8a4b1d914a34cd998de97d97f 517 Gene3D G3DSA:3.40.190.10 155 291 4.6E-35 T 06-07-2017 SMD11_RS04030 658b2dc8a4b1d914a34cd998de97d97f 517 Gene3D G3DSA:3.10.105.10 292 479 1.8E-35 T 06-07-2017 SMD11_RS04030 658b2dc8a4b1d914a34cd998de97d97f 517 PIRSF PIRSF002741 6 508 2.0E-75 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD11_RS04030 658b2dc8a4b1d914a34cd998de97d97f 517 SUPERFAMILY SSF53850 40 516 3.44E-107 T 06-07-2017 SMD11_RS29065 6d3f8aed635ffdbc4a8afa262b691926 294 SUPERFAMILY SSF47413 49 104 2.1E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS29065 6d3f8aed635ffdbc4a8afa262b691926 294 SMART SM00530 32 105 9.5E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS29065 6d3f8aed635ffdbc4a8afa262b691926 294 Pfam PF13560 Helix-turn-helix domain 30 107 1.6E-12 T 06-07-2017 SMD11_RS29065 6d3f8aed635ffdbc4a8afa262b691926 294 Gene3D G3DSA:1.10.260.40 29 104 3.9E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS16770 3ee506a9819e6fbf9a4845709e55c42f 196 Pfam PF00436 Single-strand binding protein family 7 107 3.3E-30 T 06-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 SMD11_RS16770 3ee506a9819e6fbf9a4845709e55c42f 196 SUPERFAMILY SSF50249 6 196 1.03E-43 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS16770 3ee506a9819e6fbf9a4845709e55c42f 196 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 30.129 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SMD11_RS16770 3ee506a9819e6fbf9a4845709e55c42f 196 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 6 126 1.3E-29 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SMD11_RS16770 3ee506a9819e6fbf9a4845709e55c42f 196 Gene3D G3DSA:2.40.50.140 4 116 4.9E-41 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 Pfam PF07517 SecA DEAD-like domain 6 393 5.0E-128 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 Pfam PF01043 SecA preprotein cross-linking domain 232 350 1.4E-34 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 PRINTS PR00906 SecA protein signature 368 385 7.4E-72 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 PRINTS PR00906 SecA protein signature 168 188 7.4E-72 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 PRINTS PR00906 SecA protein signature 331 353 7.4E-72 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 PRINTS PR00906 SecA protein signature 115 125 7.4E-72 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 PRINTS PR00906 SecA protein signature 99 113 7.4E-72 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 PRINTS PR00906 SecA protein signature 405 418 7.4E-72 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 PRINTS PR00906 SecA protein signature 61 85 7.4E-72 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 SUPERFAMILY SSF52540 408 625 2.25E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 SUPERFAMILY SSF52540 360 407 3.03E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 SUPERFAMILY SSF52540 3 226 3.03E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 Gene3D G3DSA:3.90.1440.10 228 360 5.9E-45 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 SMART SM00958 226 350 4.3E-66 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 ProSitePatterns PS01312 SecA family signature. 492 507 - T 06-07-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 827 0.0 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 Gene3D G3DSA:3.40.50.300 361 408 6.0E-122 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 Gene3D G3DSA:3.40.50.300 3 226 6.0E-122 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 SMART SM00957 4 394 1.8E-281 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 Gene3D G3DSA:3.40.50.300 409 626 1.5E-93 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 Pfam PF07516 SecA Wing and Scaffold domain 624 838 1.3E-65 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 Gene3D G3DSA:1.10.3060.10 655 839 1.8E-57 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 SUPERFAMILY SSF81886 627 852 3.14E-73 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 841 19.898 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SMD11_RS20820 8227eb262dc172cb28c449548d238708 939 SUPERFAMILY SSF81767 225 360 4.97E-41 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SMD11_RS17610 e047d05160237a124905b3c143ec5c5f 154 SMART SM00422 23 92 8.3E-26 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS17610 e047d05160237a124905b3c143ec5c5f 154 SUPERFAMILY SSF46955 23 120 1.19E-19 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS17610 e047d05160237a124905b3c143ec5c5f 154 ProSitePatterns PS00552 MerR-type HTH domain signature. 26 48 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS17610 e047d05160237a124905b3c143ec5c5f 154 Gene3D G3DSA:1.10.1660.10 24 122 1.3E-22 T 06-07-2017 SMD11_RS17610 e047d05160237a124905b3c143ec5c5f 154 Pfam PF13411 MerR HTH family regulatory protein 23 90 1.1E-16 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS05300 ed6354943f1a121941faf01956e70177 468 Gene3D G3DSA:3.40.640.10 83 329 3.3E-72 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS05300 ed6354943f1a121941faf01956e70177 468 Gene3D G3DSA:3.90.1150.10 330 444 5.5E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS05300 ed6354943f1a121941faf01956e70177 468 Gene3D G3DSA:3.90.1150.10 31 82 5.5E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS05300 ed6354943f1a121941faf01956e70177 468 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 278 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS05300 ed6354943f1a121941faf01956e70177 468 Pfam PF00202 Aminotransferase class-III 48 442 7.1E-89 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS05300 ed6354943f1a121941faf01956e70177 468 SUPERFAMILY SSF53383 45 444 1.99E-108 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS04790 9a51e12c906bd45242db5a0263a0eed2 338 Gene3D G3DSA:3.60.130.10 38 316 4.4E-49 T 06-07-2017 SMD11_RS04790 9a51e12c906bd45242db5a0263a0eed2 338 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 146 304 2.5E-8 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMD11_RS04790 9a51e12c906bd45242db5a0263a0eed2 338 SUPERFAMILY SSF51197 49 318 6.41E-46 T 06-07-2017 SMD11_RS04790 9a51e12c906bd45242db5a0263a0eed2 338 PIRSF PIRSF019543 2 327 8.7E-112 T 06-07-2017 IPR014503 Clavaminate synthase GO:0005506|GO:0017000|GO:0033758|GO:0055114 SMD11_RS10495 2ab1dcd38f38be7fdc27eddf27a5a371 357 Gene3D G3DSA:3.20.20.210 8 355 4.9E-66 T 06-07-2017 SMD11_RS10495 2ab1dcd38f38be7fdc27eddf27a5a371 357 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 9 325 7.4E-13 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD11_RS10495 2ab1dcd38f38be7fdc27eddf27a5a371 357 SUPERFAMILY SSF51726 8 352 3.01E-48 T 06-07-2017 SMD11_RS18980 f7d5812947f94e66e74760e50d738602 60 SUPERFAMILY SSF55129 1 60 1.83E-22 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SMD11_RS18980 f7d5812947f94e66e74760e50d738602 60 Gene3D G3DSA:3.30.1390.20 1 59 1.1E-29 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SMD11_RS18980 f7d5812947f94e66e74760e50d738602 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 2.3E-18 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SMD11_RS18980 f7d5812947f94e66e74760e50d738602 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 20.41 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 SMD11_RS18980 f7d5812947f94e66e74760e50d738602 60 PIRSF PIRSF002211 1 60 9.0E-30 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 SMD11_RS18980 f7d5812947f94e66e74760e50d738602 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 4.6E-28 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 SMD11_RS25140 c919f94079321dddb3d0982abefee1c7 111 Pfam PF13397 RNA polymerase-binding protein 5 108 1.1E-42 T 06-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 SMD11_RS25140 c919f94079321dddb3d0982abefee1c7 111 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 17 110 23.747 T 06-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 SMD11_RS25140 c919f94079321dddb3d0982abefee1c7 111 ProSitePatterns PS00202 Rubredoxin signature. 51 61 - T 06-07-2017 IPR018527 Rubredoxin, iron-binding site GO:0046872 SMD11_RS34220 cca8014bed8fc291de5f04093930a976 157 Gene3D G3DSA:1.10.10.10 15 151 4.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS34220 cca8014bed8fc291de5f04093930a976 157 SMART SM00347 35 135 1.7E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS34220 cca8014bed8fc291de5f04093930a976 157 ProSitePatterns PS01117 MarR-type HTH domain signature. 74 108 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site SMD11_RS34220 cca8014bed8fc291de5f04093930a976 157 SUPERFAMILY SSF46785 14 150 6.23E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS34220 cca8014bed8fc291de5f04093930a976 157 Pfam PF12802 MarR family 44 98 5.4E-10 T 06-07-2017 SMD11_RS25380 5213204a81177ba2715d2a4153bc7c7f 701 Gene3D G3DSA:1.10.8.80 249 336 2.5E-34 T 06-07-2017 SMD11_RS25380 5213204a81177ba2715d2a4153bc7c7f 701 SUPERFAMILY SSF53300 516 653 6.82E-22 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS25380 5213204a81177ba2715d2a4153bc7c7f 701 Gene3D G3DSA:3.40.50.300 5 202 4.0E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25380 5213204a81177ba2715d2a4153bc7c7f 701 TIGRFAM TIGR02442 Cob-chelat-sub: cobaltochelatase subunit 6 678 3.1E-250 T 06-07-2017 IPR012804 Cobaltochelatase subunit, putative SMD11_RS25380 5213204a81177ba2715d2a4153bc7c7f 701 Pfam PF01078 Magnesium chelatase, subunit ChlI 117 183 1.5E-7 T 06-07-2017 IPR000523 Magnesium chelatase ChlI domain SMD11_RS25380 5213204a81177ba2715d2a4153bc7c7f 701 SMART SM00327 513 690 1.2E-18 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS25380 5213204a81177ba2715d2a4153bc7c7f 701 SMART SM00382 29 206 7.6E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS25380 5213204a81177ba2715d2a4153bc7c7f 701 Pfam PF13519 von Willebrand factor type A domain 516 622 1.5E-15 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS25380 5213204a81177ba2715d2a4153bc7c7f 701 SUPERFAMILY SSF52540 6 330 3.84E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25380 5213204a81177ba2715d2a4153bc7c7f 701 Gene3D G3DSA:3.40.50.410 516 647 4.1E-13 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Gene3D G3DSA:3.40.50.1820 2082 2140 1.8E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Gene3D G3DSA:3.40.50.1820 1875 1995 1.8E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Pfam PF00501 AMP-binding enzyme 224 620 9.6E-94 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Pfam PF00501 AMP-binding enzyme 1286 1685 2.4E-101 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Gene3D G3DSA:3.30.300.30 1680 1796 1.1E-37 T 06-07-2017 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Gene3D G3DSA:3.30.300.30 616 730 1.3E-34 T 06-07-2017 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Pfam PF13745 HxxPF-repeated domain 75 168 7.2E-27 T 06-07-2017 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Pfam PF13745 HxxPF-repeated domain 1140 1233 2.7E-23 T 06-07-2017 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 SMART SM00823 Phosphopantetheine attachment site 1793 1862 0.012 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 SMART SM00823 Phosphopantetheine attachment site 728 799 1.6E-5 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Pfam PF00975 Thioesterase domain 1888 2138 5.8E-27 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 SUPERFAMILY SSF47336 1786 1858 6.94E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 SUPERFAMILY SSF56801 182 741 4.97E-156 T 06-07-2017 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 ProSitePatterns PS00455 Putative AMP-binding domain signature. 368 379 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Gene3D G3DSA:3.40.50.980 1434 1596 2.9E-52 T 06-07-2017 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Gene3D G3DSA:3.40.50.980 374 515 9.9E-38 T 06-07-2017 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1817 1832 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 ProSitePatterns PS00012 Phosphopantetheine attachment site. 754 769 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 SMART SM00824 Thioesterase 1893 2140 7.2E-6 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Gene3D G3DSA:3.40.50.980 1279 1433 1.8E-47 T 06-07-2017 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1424 1435 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Pfam PF00668 Condensation domain 831 1117 1.4E-68 T 06-07-2017 IPR001242 Condensation domain SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Pfam PF00668 Condensation domain 3 52 6.5E-10 T 06-07-2017 IPR001242 Condensation domain SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Gene3D G3DSA:3.40.50.980 219 373 5.4E-42 T 06-07-2017 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1307 1708 2.0E-132 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 244 643 8.6E-129 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Pfam PF13193 AMP-binding enzyme C-terminal domain 628 703 2.0E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Pfam PF13193 AMP-binding enzyme C-terminal domain 1693 1768 7.6E-13 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 SUPERFAMILY SSF56801 1245 1805 3.27E-165 T 06-07-2017 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 SUPERFAMILY SSF52777 1008 1250 4.11E-58 T 06-07-2017 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Gene3D G3DSA:2.30.38.10 1597 1675 3.3E-26 T 06-07-2017 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Gene3D G3DSA:2.30.38.10 529 610 2.7E-28 T 06-07-2017 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 SUPERFAMILY SSF52777 3 207 3.67E-44 T 06-07-2017 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 SUPERFAMILY SSF47336 722 796 4.32E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 SUPERFAMILY SSF53474 1874 2140 5.88E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Gene3D G3DSA:1.10.1200.10 731 800 2.5E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Gene3D G3DSA:1.10.1200.10 1797 1863 2.2E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 SUPERFAMILY SSF52777 829 1000 2.0E-51 T 06-07-2017 SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Pfam PF00550 Phosphopantetheine attachment site 1795 1858 1.4E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32940 2c172636dfb887a38f59376afa7b70e3 2144 Pfam PF00550 Phosphopantetheine attachment site 730 795 6.2E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS22065 20f8c8bdbcfe462067f4c99c6f9e4c53 892 SMART SM00220 241 496 7.1E-13 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS22065 20f8c8bdbcfe462067f4c99c6f9e4c53 892 Pfam PF00069 Protein kinase domain 245 441 1.0E-23 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS22065 20f8c8bdbcfe462067f4c99c6f9e4c53 892 Gene3D G3DSA:3.30.200.20 235 329 7.7E-13 T 06-07-2017 SMD11_RS22065 20f8c8bdbcfe462067f4c99c6f9e4c53 892 SUPERFAMILY SSF56112 232 509 7.02E-39 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS22065 20f8c8bdbcfe462067f4c99c6f9e4c53 892 SUPERFAMILY SSF48452 650 758 7.59E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS22065 20f8c8bdbcfe462067f4c99c6f9e4c53 892 Pfam PF16918 Protein kinase G tetratricopeptide repeat 583 890 4.0E-89 T 06-07-2017 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 SMD11_RS22065 20f8c8bdbcfe462067f4c99c6f9e4c53 892 Gene3D G3DSA:1.10.510.10 330 441 2.0E-19 T 06-07-2017 SMD11_RS22065 20f8c8bdbcfe462067f4c99c6f9e4c53 892 Gene3D G3DSA:1.25.40.10 633 759 3.7E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS22065 20f8c8bdbcfe462067f4c99c6f9e4c53 892 Pfam PF16919 Protein kinase G rubredoxin domain 105 240 4.6E-40 T 06-07-2017 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 SMD11_RS06525 994459cbb72d14a55d73b9650ca7fa5b 379 PIRSF PIRSF006078 8 378 4.2E-115 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMD11_RS06525 994459cbb72d14a55d73b9650ca7fa5b 379 SUPERFAMILY SSF110738 9 371 7.85E-111 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMD11_RS06525 994459cbb72d14a55d73b9650ca7fa5b 379 Gene3D G3DSA:3.90.1510.10 50 276 5.3E-81 T 06-07-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 SMD11_RS06525 994459cbb72d14a55d73b9650ca7fa5b 379 Pfam PF02595 Glycerate kinase family 10 371 1.6E-125 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMD11_RS06525 994459cbb72d14a55d73b9650ca7fa5b 379 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 9 371 2.4E-110 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 Gene3D G3DSA:3.90.700.10 247 354 3.5E-35 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 19 38 2.3E-9 T 06-07-2017 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 361 383 2.3E-9 T 06-07-2017 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 SUPERFAMILY SSF56425 241 358 7.03E-38 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 641 903 4.0E-87 T 06-07-2017 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 Pfam PF02910 Fumarate reductase flavoprotein C-term 449 544 2.5E-17 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 Gene3D G3DSA:1.20.58.100 441 545 1.6E-25 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 SUPERFAMILY SSF51905 5 270 4.91E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 SUPERFAMILY SSF51905 362 417 4.91E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 16 527 5.8E-164 T 06-07-2017 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 Pfam PF00890 FAD binding domain 18 398 1.3E-94 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 18 40 1.0E-5 T 06-07-2017 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 376 383 1.0E-5 T 06-07-2017 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 739 903 1.4E-52 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 SUPERFAMILY SSF46977 445 561 1.7E-31 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 SUPERFAMILY SSF51690 739 904 1.37E-53 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 Gene3D G3DSA:3.90.1170.20 629 758 1.3E-42 T 06-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 SUPERFAMILY SSF54675 628 738 1.26E-25 T 06-07-2017 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 Gene3D G3DSA:3.50.50.60 355 414 1.1E-96 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 Gene3D G3DSA:3.50.50.60 12 246 1.1E-96 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 Gene3D G3DSA:3.20.20.70 759 894 5.9E-53 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS14845 e0da0b4baf05d2f8a0e8f46c99b2eb31 909 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 649 737 1.4E-22 T 06-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 SMD11_RS20605 68b01b2a39cc754f89059793075d1518 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 384 1.5E-51 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS20605 68b01b2a39cc754f89059793075d1518 386 SUPERFAMILY SSF47203 233 384 5.68E-60 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS20605 68b01b2a39cc754f89059793075d1518 386 Gene3D G3DSA:2.40.110.10 128 223 5.3E-42 T 06-07-2017 SMD11_RS20605 68b01b2a39cc754f89059793075d1518 386 SUPERFAMILY SSF56645 13 247 9.29E-80 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS20605 68b01b2a39cc754f89059793075d1518 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD11_RS20605 68b01b2a39cc754f89059793075d1518 386 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD11_RS20605 68b01b2a39cc754f89059793075d1518 386 Gene3D G3DSA:1.20.140.10 224 384 5.5E-71 T 06-07-2017 SMD11_RS20605 68b01b2a39cc754f89059793075d1518 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 124 1.6E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS20605 68b01b2a39cc754f89059793075d1518 386 Gene3D G3DSA:1.10.540.10 13 124 3.9E-32 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS20605 68b01b2a39cc754f89059793075d1518 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 223 5.4E-28 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS19000 3a0052e56a3bd38aa75bfb38ace6255b 278 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 257 1.0E-81 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 SMD11_RS19000 3a0052e56a3bd38aa75bfb38ace6255b 278 Pfam PF00557 Metallopeptidase family M24 11 249 8.4E-43 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS19000 3a0052e56a3bd38aa75bfb38ace6255b 278 Gene3D G3DSA:3.90.230.10 3 259 2.6E-75 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS19000 3a0052e56a3bd38aa75bfb38ace6255b 278 SUPERFAMILY SSF55920 1 259 6.54E-72 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS19000 3a0052e56a3bd38aa75bfb38ace6255b 278 Hamap MF_01974 Methionine aminopeptidase [map]. 2 258 37.514 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 SMD11_RS19000 3a0052e56a3bd38aa75bfb38ace6255b 278 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 173 191 - T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 SMD11_RS19000 3a0052e56a3bd38aa75bfb38ace6255b 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 167 179 2.3E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase SMD11_RS19000 3a0052e56a3bd38aa75bfb38ace6255b 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 2.3E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase SMD11_RS19000 3a0052e56a3bd38aa75bfb38ace6255b 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 2.3E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase SMD11_RS19000 3a0052e56a3bd38aa75bfb38ace6255b 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 200 212 2.3E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase SMD11_RS16585 582a8693074ab7b4ae1dd2afeddc234b 465 Gene3D G3DSA:2.60.60.30 12 164 8.9E-30 T 06-07-2017 SMD11_RS16585 582a8693074ab7b4ae1dd2afeddc234b 465 SMART SM00327 247 438 5.0E-13 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS16585 582a8693074ab7b4ae1dd2afeddc234b 465 Pfam PF02342 TerD domain 1 166 6.0E-41 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS16585 582a8693074ab7b4ae1dd2afeddc234b 465 Pfam PF10138 vWA found in TerF C terminus 247 465 1.3E-84 T 06-07-2017 IPR019303 vWA found in TerF C terminus SMD11_RS16585 582a8693074ab7b4ae1dd2afeddc234b 465 SUPERFAMILY SSF53300 248 439 5.4E-9 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS17845 3194288e2c1993ff64b0872bf67cadf6 346 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS17845 3194288e2c1993ff64b0872bf67cadf6 346 SUPERFAMILY SSF51735 19 337 2.27E-94 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17845 3194288e2c1993ff64b0872bf67cadf6 346 Pfam PF16363 GDP-mannose 4,6 dehydratase 26 327 1.3E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17845 3194288e2c1993ff64b0872bf67cadf6 346 Gene3D G3DSA:3.40.50.720 24 207 9.6E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17845 3194288e2c1993ff64b0872bf67cadf6 346 Gene3D G3DSA:3.90.25.10 208 335 1.1E-30 T 06-07-2017 SMD11_RS11430 5c21acda7ff4eecb47ba531988d81726 700 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS11430 5c21acda7ff4eecb47ba531988d81726 700 ProSitePatterns PS00211 ABC transporters family signature. 513 527 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS11430 5c21acda7ff4eecb47ba531988d81726 700 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 592 654 1.5E-14 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS11430 5c21acda7ff4eecb47ba531988d81726 700 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 313 4.1E-18 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS11430 5c21acda7ff4eecb47ba531988d81726 700 SUPERFAMILY SSF52540 363 612 6.48E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11430 5c21acda7ff4eecb47ba531988d81726 700 Gene3D G3DSA:3.40.50.300 19 271 8.7E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11430 5c21acda7ff4eecb47ba531988d81726 700 Gene3D G3DSA:3.40.50.300 362 614 2.6E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11430 5c21acda7ff4eecb47ba531988d81726 700 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 247 331 1.8E-22 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS11430 5c21acda7ff4eecb47ba531988d81726 700 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 591 686 3.2E-19 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS11430 5c21acda7ff4eecb47ba531988d81726 700 SUPERFAMILY SSF52540 20 267 1.21E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11430 5c21acda7ff4eecb47ba531988d81726 700 SMART SM00382 399 590 8.2E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS11430 5c21acda7ff4eecb47ba531988d81726 700 SMART SM00382 49 247 9.7E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS11430 5c21acda7ff4eecb47ba531988d81726 700 Pfam PF00005 ABC transporter 391 540 1.0E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS11430 5c21acda7ff4eecb47ba531988d81726 700 Pfam PF00005 ABC transporter 41 197 6.7E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS18815 37749e27edf104b680b37301a94cc246 293 Gene3D G3DSA:3.30.70.940 105 213 1.7E-41 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SMD11_RS18815 37749e27edf104b680b37301a94cc246 293 Gene3D G3DSA:2.30.30.30 238 292 2.0E-25 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 SMD11_RS18815 37749e27edf104b680b37301a94cc246 293 SMART SM00738 103 211 1.6E-45 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SMD11_RS18815 37749e27edf104b680b37301a94cc246 293 ProSitePatterns PS01014 Transcription termination factor nusG signature. 276 285 - T 06-07-2017 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site SMD11_RS18815 37749e27edf104b680b37301a94cc246 293 SMART SM00739 239 266 3.5E-4 T 06-07-2017 IPR005824 KOW SMD11_RS18815 37749e27edf104b680b37301a94cc246 293 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 106 292 2.1E-54 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 SMD11_RS18815 37749e27edf104b680b37301a94cc246 293 SUPERFAMILY SSF82679 105 211 3.66E-35 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SMD11_RS18815 37749e27edf104b680b37301a94cc246 293 SUPERFAMILY SSF50104 238 292 5.01E-15 T 06-07-2017 IPR008991 Translation protein SH3-like domain SMD11_RS18815 37749e27edf104b680b37301a94cc246 293 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 103 293 22.597 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 SMD11_RS18815 37749e27edf104b680b37301a94cc246 293 PRINTS PR00338 Transcription termination factor NUSG signature 269 285 4.4E-18 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 SMD11_RS18815 37749e27edf104b680b37301a94cc246 293 PRINTS PR00338 Transcription termination factor NUSG signature 158 170 4.4E-18 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 SMD11_RS18815 37749e27edf104b680b37301a94cc246 293 PRINTS PR00338 Transcription termination factor NUSG signature 251 266 4.4E-18 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 SMD11_RS18815 37749e27edf104b680b37301a94cc246 293 Pfam PF02357 Transcription termination factor nusG 105 207 1.6E-22 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SMD11_RS27870 361af13fa4983a406d1bb5461cc983a4 191 Pfam PF04186 FxsA cytoplasmic membrane protein 33 142 2.9E-28 T 06-07-2017 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 SMART SM00220 11 277 4.1E-68 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 Gene3D G3DSA:3.30.200.20 4 94 1.2E-29 T 06-07-2017 SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 Pfam PF03793 PASTA domain 446 507 6.2E-13 T 06-07-2017 IPR005543 PASTA domain SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 Pfam PF03793 PASTA domain 379 440 3.4E-12 T 06-07-2017 IPR005543 PASTA domain SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 Pfam PF03793 PASTA domain 514 574 1.1E-14 T 06-07-2017 IPR005543 PASTA domain SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 Pfam PF03793 PASTA domain 579 636 8.6E-7 T 06-07-2017 IPR005543 PASTA domain SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 SMART SM00740 575 639 0.0022 T 06-07-2017 IPR005543 PASTA domain SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 SMART SM00740 375 441 2.3E-10 T 06-07-2017 IPR005543 PASTA domain SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 SMART SM00740 442 508 1.3E-14 T 06-07-2017 IPR005543 PASTA domain SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 SMART SM00740 509 574 3.4E-18 T 06-07-2017 IPR005543 PASTA domain SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 SUPERFAMILY SSF54184 378 440 1.57E-6 T 06-07-2017 SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 Gene3D G3DSA:1.10.510.10 98 274 1.9E-49 T 06-07-2017 SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 Pfam PF00069 Protein kinase domain 11 265 2.8E-51 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS17030 d81e723d9871b4d86064f00769a51365 679 SUPERFAMILY SSF56112 7 274 2.83E-78 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS21665 c0baebca2e72c5ca1e0aa5c109dd0888 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 297 2.0E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21665 c0baebca2e72c5ca1e0aa5c109dd0888 310 Gene3D G3DSA:1.10.3720.10 42 295 2.9E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21665 c0baebca2e72c5ca1e0aa5c109dd0888 310 SUPERFAMILY SSF161098 41 310 3.16E-55 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS30935 7f525c8e8189ca9c991b6f42a7963196 976 SMART SM00065 402 584 1.0E-6 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS30935 7f525c8e8189ca9c991b6f42a7963196 976 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 630 825 5.5E-56 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS30935 7f525c8e8189ca9c991b6f42a7963196 976 SMART SM00331 602 825 6.2E-39 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS30935 7f525c8e8189ca9c991b6f42a7963196 976 Gene3D G3DSA:3.30.450.40 407 582 8.6E-38 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS30935 7f525c8e8189ca9c991b6f42a7963196 976 SUPERFAMILY SSF55874 869 947 1.73E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS30935 7f525c8e8189ca9c991b6f42a7963196 976 SUPERFAMILY SSF55781 460 578 1.07E-15 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS30935 7f525c8e8189ca9c991b6f42a7963196 976 Pfam PF13581 Histidine kinase-like ATPase domain 838 946 1.8E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS30935 7f525c8e8189ca9c991b6f42a7963196 976 Pfam PF01590 GAF domain 420 574 1.8E-10 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS30935 7f525c8e8189ca9c991b6f42a7963196 976 SUPERFAMILY SSF81606 616 824 5.36E-12 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS21130 0976ce1720e046a46a792b7d319351e5 327 Gene3D G3DSA:3.40.190.120 157 262 7.4E-31 T 06-07-2017 SMD11_RS21130 0976ce1720e046a46a792b7d319351e5 327 SUPERFAMILY SSF53850 51 323 2.28E-52 T 06-07-2017 SMD11_RS21130 0976ce1720e046a46a792b7d319351e5 327 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 51 318 1.2E-52 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SMD11_RS21130 0976ce1720e046a46a792b7d319351e5 327 Gene3D G3DSA:3.40.190.10 49 156 2.3E-48 T 06-07-2017 SMD11_RS21130 0976ce1720e046a46a792b7d319351e5 327 Gene3D G3DSA:3.40.190.10 274 324 2.3E-48 T 06-07-2017 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 SUPERFAMILY SSF53067 164 400 2.05E-84 T 06-07-2017 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 TIGRFAM TIGR00016 ackA: acetate kinase 6 400 3.0E-146 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 Pfam PF00871 Acetokinase family 8 394 3.8E-152 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 Hamap MF_00020 Acetate kinase [ackA]. 1 403 179.281 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 209 226 - T 06-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 Gene3D G3DSA:3.30.420.40 211 400 2.2E-78 T 06-07-2017 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 PIRSF PIRSF000722 4 403 5.1E-145 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 Gene3D G3DSA:3.30.420.40 6 210 5.0E-13 T 06-07-2017 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 PRINTS PR00471 Acetate kinase family signature 327 343 6.7E-45 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 PRINTS PR00471 Acetate kinase family signature 8 19 6.7E-45 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 PRINTS PR00471 Acetate kinase family signature 305 318 6.7E-45 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 PRINTS PR00471 Acetate kinase family signature 179 192 6.7E-45 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 PRINTS PR00471 Acetate kinase family signature 209 230 6.7E-45 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 PRINTS PR00471 Acetate kinase family signature 382 394 6.7E-45 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 SUPERFAMILY SSF53067 7 202 4.66E-63 T 06-07-2017 SMD11_RS10565 3e9b2472ce744f0391ba5b77333c3dcb 403 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 8 19 - T 06-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SMD11_RS25910 ee8685a40258c508fd0639016bd5e940 268 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 17 256 7.3E-51 T 06-07-2017 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 SMD11_RS18880 d35654293dc2e94d70aeab4558b9f5eb 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.897 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18880 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.6E-21 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18880 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.6E-21 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18880 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.6E-21 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18880 d35654293dc2e94d70aeab4558b9f5eb 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 7.9E-37 T 06-07-2017 IPR027486 Ribosomal protein S10 domain SMD11_RS18880 d35654293dc2e94d70aeab4558b9f5eb 102 SUPERFAMILY SSF54999 5 102 1.02E-38 T 06-07-2017 IPR027486 Ribosomal protein S10 domain SMD11_RS18880 d35654293dc2e94d70aeab4558b9f5eb 102 SMART SM01403 7 101 3.5E-59 T 06-07-2017 IPR027486 Ribosomal protein S10 domain SMD11_RS18880 d35654293dc2e94d70aeab4558b9f5eb 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 06-07-2017 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18880 d35654293dc2e94d70aeab4558b9f5eb 102 Gene3D G3DSA:3.30.70.600 4 102 5.6E-45 T 06-07-2017 IPR027486 Ribosomal protein S10 domain SMD11_RS18880 d35654293dc2e94d70aeab4558b9f5eb 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.1E-47 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS33940 d183394ac6aa8602366da478ac633079 325 Pfam PF01040 UbiA prenyltransferase family 52 306 1.9E-64 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 SMD11_RS33940 d183394ac6aa8602366da478ac633079 325 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 40 321 1.9E-92 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 SMD11_RS33940 d183394ac6aa8602366da478ac633079 325 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 36 323 18.567 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 SMD11_RS33940 d183394ac6aa8602366da478ac633079 325 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 91 113 - T 06-07-2017 IPR030470 UbiA prenyltransferase conserved site SMD11_RS24090 3f7693977a3ac1642615aa01bee6905c 265 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 265 42.216 T 06-07-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD11_RS24090 3f7693977a3ac1642615aa01bee6905c 265 Pfam PF02654 Cobalamin-5-phosphate synthase 18 260 2.4E-44 T 06-07-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD11_RS08720 d4244740b693dbb5f9c7589986d3fd5e 637 SMART SM00382 28 205 8.7E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS08720 d4244740b693dbb5f9c7589986d3fd5e 637 Gene3D G3DSA:3.40.50.300 17 223 7.8E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08720 d4244740b693dbb5f9c7589986d3fd5e 637 Pfam PF00005 ABC transporter 20 156 4.6E-17 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS08720 d4244740b693dbb5f9c7589986d3fd5e 637 SUPERFAMILY SSF52540 14 217 1.88E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24705 0603028c1a600cac5c9b79c9f2e6c326 251 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 251 48.001 T 06-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 SMD11_RS24705 0603028c1a600cac5c9b79c9f2e6c326 251 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 251 1.4E-110 T 06-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 SMD11_RS24705 0603028c1a600cac5c9b79c9f2e6c326 251 Pfam PF00977 Histidine biosynthesis protein 6 234 2.3E-87 T 06-07-2017 IPR006062 Histidine biosynthesis GO:0000105 SMD11_RS24705 0603028c1a600cac5c9b79c9f2e6c326 251 SUPERFAMILY SSF51366 3 251 2.43E-83 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMD11_RS24705 0603028c1a600cac5c9b79c9f2e6c326 251 Gene3D G3DSA:3.20.20.70 6 251 7.1E-103 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS10260 0c3fd6e331272b5737d8ec56b01a0da5 591 Gene3D G3DSA:3.10.105.10 350 558 3.7E-34 T 06-07-2017 SMD11_RS10260 0c3fd6e331272b5737d8ec56b01a0da5 591 Gene3D G3DSA:3.90.76.10 72 241 4.4E-31 T 06-07-2017 SMD11_RS10260 0c3fd6e331272b5737d8ec56b01a0da5 591 PIRSF PIRSF002741 12 583 1.6E-54 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD11_RS10260 0c3fd6e331272b5737d8ec56b01a0da5 591 Gene3D G3DSA:3.40.190.10 242 349 8.7E-18 T 06-07-2017 SMD11_RS10260 0c3fd6e331272b5737d8ec56b01a0da5 591 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 109 501 3.0E-67 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain SMD11_RS10260 0c3fd6e331272b5737d8ec56b01a0da5 591 SUPERFAMILY SSF53850 59 586 1.5E-88 T 06-07-2017 SMD11_RS14500 e30ec2a8a875e3175a45e2d5a5f272ae 136 Gene3D G3DSA:3.10.180.10 5 121 1.6E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS14500 e30ec2a8a875e3175a45e2d5a5f272ae 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 118 5.9E-6 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS14500 e30ec2a8a875e3175a45e2d5a5f272ae 136 SUPERFAMILY SSF54593 5 120 3.95E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS07940 bbf0d86c801b2ce13824cbfa62378183 426 PIRSF PIRSF006356 1 407 2.1E-147 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD11_RS07940 bbf0d86c801b2ce13824cbfa62378183 426 Pfam PF02274 Amidinotransferase 17 404 2.3E-86 T 06-07-2017 SMD11_RS07940 bbf0d86c801b2ce13824cbfa62378183 426 Gene3D G3DSA:3.75.10.10 151 407 3.8E-128 T 06-07-2017 SMD11_RS07940 bbf0d86c801b2ce13824cbfa62378183 426 Gene3D G3DSA:3.75.10.10 2 66 3.8E-128 T 06-07-2017 SMD11_RS07940 bbf0d86c801b2ce13824cbfa62378183 426 PRINTS PR01466 Bacterial arginine deiminase signature 386 404 8.7E-49 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD11_RS07940 bbf0d86c801b2ce13824cbfa62378183 426 PRINTS PR01466 Bacterial arginine deiminase signature 151 169 8.7E-49 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD11_RS07940 bbf0d86c801b2ce13824cbfa62378183 426 PRINTS PR01466 Bacterial arginine deiminase signature 179 194 8.7E-49 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD11_RS07940 bbf0d86c801b2ce13824cbfa62378183 426 PRINTS PR01466 Bacterial arginine deiminase signature 363 377 8.7E-49 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD11_RS07940 bbf0d86c801b2ce13824cbfa62378183 426 PRINTS PR01466 Bacterial arginine deiminase signature 1 21 8.7E-49 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD11_RS07940 bbf0d86c801b2ce13824cbfa62378183 426 PRINTS PR01466 Bacterial arginine deiminase signature 343 360 8.7E-49 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD11_RS07940 bbf0d86c801b2ce13824cbfa62378183 426 SUPERFAMILY SSF55909 2 407 2.36E-124 T 06-07-2017 SMD11_RS07940 bbf0d86c801b2ce13824cbfa62378183 426 Hamap MF_00242 Arginine deiminase [arcA]. 1 407 41.886 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SMD11_RS06950 fc315908ec7c00b923889a535e69eddd 125 Pfam PF00576 HIUase/Transthyretin family 10 124 1.9E-30 T 06-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 SMD11_RS06950 fc315908ec7c00b923889a535e69eddd 125 ProSitePatterns PS00768 Transthyretin signature 1. 13 28 - T 06-07-2017 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 SMD11_RS06950 fc315908ec7c00b923889a535e69eddd 125 SUPERFAMILY SSF49472 7 125 6.54E-29 T 06-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 SMD11_RS06950 fc315908ec7c00b923889a535e69eddd 125 Gene3D G3DSA:2.60.40.180 8 125 5.8E-32 T 06-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 SMD11_RS06950 fc315908ec7c00b923889a535e69eddd 125 PRINTS PR00189 Transthyretin signature 9 29 3.1E-6 T 06-07-2017 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 SMD11_RS06950 fc315908ec7c00b923889a535e69eddd 125 PRINTS PR00189 Transthyretin signature 103 125 3.1E-6 T 06-07-2017 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 SMD11_RS06950 fc315908ec7c00b923889a535e69eddd 125 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 9 125 1.2E-28 T 06-07-2017 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394 SMD11_RS04100 0155051064148c747be01d283e4ef530 259 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 70 75 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD11_RS04100 0155051064148c747be01d283e4ef530 259 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 60 75 2.5E-11 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD11_RS04100 0155051064148c747be01d283e4ef530 259 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 117 131 2.5E-11 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD11_RS04100 0155051064148c747be01d283e4ef530 259 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 207 219 2.5E-11 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD11_RS04100 0155051064148c747be01d283e4ef530 259 Gene3D G3DSA:2.40.10.10 34 68 3.1E-13 T 06-07-2017 SMD11_RS04100 0155051064148c747be01d283e4ef530 259 Pfam PF00089 Trypsin 35 248 1.1E-40 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD11_RS04100 0155051064148c747be01d283e4ef530 259 SMART SM00020 32 250 3.3E-27 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD11_RS04100 0155051064148c747be01d283e4ef530 259 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 208 219 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site SMD11_RS04100 0155051064148c747be01d283e4ef530 259 SUPERFAMILY SSF50494 31 247 3.7E-46 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS04100 0155051064148c747be01d283e4ef530 259 Gene3D G3DSA:2.40.10.10 69 246 5.7E-36 T 06-07-2017 SMD11_RS07760 9ae9cb890b51c7cae1cfee7b788ed324 422 SMART SM00825 Beta-ketoacyl synthase 4 420 1.0E-11 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS07760 9ae9cb890b51c7cae1cfee7b788ed324 422 Gene3D G3DSA:3.40.47.10 2 264 4.3E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07760 9ae9cb890b51c7cae1cfee7b788ed324 422 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 375 2.9E-27 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS07760 9ae9cb890b51c7cae1cfee7b788ed324 422 SUPERFAMILY SSF53901 2 258 1.33E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07760 9ae9cb890b51c7cae1cfee7b788ed324 422 SUPERFAMILY SSF53901 221 418 1.98E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07760 9ae9cb890b51c7cae1cfee7b788ed324 422 Gene3D G3DSA:3.40.47.10 272 420 1.4E-47 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07760 9ae9cb890b51c7cae1cfee7b788ed324 422 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 253 1.2E-38 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS25590 3de889f23ef1285a3e1d1af512b1ec6f 172 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 136 3.8E-12 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS25590 3de889f23ef1285a3e1d1af512b1ec6f 172 SUPERFAMILY SSF53254 6 155 4.5E-27 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS25590 3de889f23ef1285a3e1d1af512b1ec6f 172 SMART SM00855 8 119 4.8E-6 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS25590 3de889f23ef1285a3e1d1af512b1ec6f 172 Gene3D G3DSA:3.40.50.1240 3 171 9.7E-57 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS20835 21b4c76411fbdb040d884eadbad10fc6 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 185 1.6E-9 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS20835 21b4c76411fbdb040d884eadbad10fc6 226 SUPERFAMILY SSF56784 6 211 3.42E-31 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS20835 21b4c76411fbdb040d884eadbad10fc6 226 Gene3D G3DSA:3.40.50.1000 68 212 9.2E-16 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS24955 4cedd4f91f82e632569c92d97568f6df 346 Pfam PF11271 Protein of unknown function (DUF3068) 5 304 2.4E-75 T 06-07-2017 IPR021424 Protein of unknown function DUF3068 SMD11_RS29875 fc22605cd6eeb5f22dd472f3c8df820a 201 Gene3D G3DSA:3.40.1050.10 18 194 3.0E-54 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS29875 fc22605cd6eeb5f22dd472f3c8df820a 201 SMART SM00947 29 192 2.6E-57 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS29875 fc22605cd6eeb5f22dd472f3c8df820a 201 SUPERFAMILY SSF53056 19 200 3.92E-52 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS29875 fc22605cd6eeb5f22dd472f3c8df820a 201 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 84 104 - T 06-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS29875 fc22605cd6eeb5f22dd472f3c8df820a 201 Pfam PF00484 Carbonic anhydrase 36 188 1.0E-41 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS29875 fc22605cd6eeb5f22dd472f3c8df820a 201 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 41 48 - T 06-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS00350 8e7590cb0777012ceb2213928c71a4ab 461 Pfam PF00067 Cytochrome P450 14 441 1.3E-70 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00350 8e7590cb0777012ceb2213928c71a4ab 461 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 398 407 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS00350 8e7590cb0777012ceb2213928c71a4ab 461 PRINTS PR00385 P450 superfamily signature 269 286 2.9E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00350 8e7590cb0777012ceb2213928c71a4ab 461 PRINTS PR00385 P450 superfamily signature 396 405 2.9E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00350 8e7590cb0777012ceb2213928c71a4ab 461 PRINTS PR00385 P450 superfamily signature 405 416 2.9E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00350 8e7590cb0777012ceb2213928c71a4ab 461 PRINTS PR00385 P450 superfamily signature 321 332 2.9E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00350 8e7590cb0777012ceb2213928c71a4ab 461 PRINTS PR00463 E-class P450 group I signature 405 428 1.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00350 8e7590cb0777012ceb2213928c71a4ab 461 PRINTS PR00463 E-class P450 group I signature 395 405 1.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00350 8e7590cb0777012ceb2213928c71a4ab 461 PRINTS PR00463 E-class P450 group I signature 34 53 1.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00350 8e7590cb0777012ceb2213928c71a4ab 461 PRINTS PR00463 E-class P450 group I signature 144 162 1.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00350 8e7590cb0777012ceb2213928c71a4ab 461 PRINTS PR00463 E-class P450 group I signature 360 384 1.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00350 8e7590cb0777012ceb2213928c71a4ab 461 PRINTS PR00463 E-class P450 group I signature 258 275 1.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00350 8e7590cb0777012ceb2213928c71a4ab 461 PRINTS PR00463 E-class P450 group I signature 278 304 1.0E-19 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00350 8e7590cb0777012ceb2213928c71a4ab 461 Gene3D G3DSA:1.10.630.10 11 458 5.2E-103 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00350 8e7590cb0777012ceb2213928c71a4ab 461 SUPERFAMILY SSF48264 11 457 2.1E-97 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02420 42740c4d00c936e54ee4ab3ee461a983 184 Gene3D G3DSA:3.90.79.10 10 180 4.1E-36 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS02420 42740c4d00c936e54ee4ab3ee461a983 184 SUPERFAMILY SSF55811 10 179 1.18E-34 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS02420 42740c4d00c936e54ee4ab3ee461a983 184 Pfam PF00293 NUDIX domain 49 157 3.7E-15 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS25495 c4c0db15b09a1ae8e90af31dc53ff207 337 SUPERFAMILY SSF53098 18 182 4.11E-43 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS25495 c4c0db15b09a1ae8e90af31dc53ff207 337 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 247 319 3.7E-5 T 06-07-2017 IPR001357 BRCT domain SMD11_RS25495 c4c0db15b09a1ae8e90af31dc53ff207 337 Gene3D G3DSA:3.40.50.10190 244 321 8.3E-13 T 06-07-2017 IPR001357 BRCT domain SMD11_RS25495 c4c0db15b09a1ae8e90af31dc53ff207 337 SUPERFAMILY SSF52113 244 321 8.63E-12 T 06-07-2017 IPR001357 BRCT domain SMD11_RS25495 c4c0db15b09a1ae8e90af31dc53ff207 337 Pfam PF00929 Exonuclease 24 176 2.6E-22 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD11_RS25495 c4c0db15b09a1ae8e90af31dc53ff207 337 SMART SM00479 21 185 8.1E-35 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD11_RS25495 c4c0db15b09a1ae8e90af31dc53ff207 337 Gene3D G3DSA:3.30.420.10 19 180 1.2E-44 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS25495 c4c0db15b09a1ae8e90af31dc53ff207 337 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 21 177 2.1E-24 T 06-07-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 SMART SM00382 355 500 1.2E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 PIRSF PIRSF001174 2 790 5.9E-241 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 Hamap MF_01973 Lon protease [lon]. 10 788 59.195 T 06-07-2017 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 578 787 4.6E-75 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 Gene3D G3DSA:3.30.230.10 603 787 2.3E-69 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 Gene3D G3DSA:1.10.8.60 500 591 6.3E-26 T 06-07-2017 SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 360 495 1.0E-20 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 SUPERFAMILY SSF54211 608 786 2.16E-52 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 719 738 1.2E-50 T 06-07-2017 SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 689 708 1.2E-50 T 06-07-2017 SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 608 624 1.2E-50 T 06-07-2017 SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 742 760 1.2E-50 T 06-07-2017 SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 363 382 1.2E-50 T 06-07-2017 SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 9 195 5.6E-16 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 Gene3D G3DSA:3.40.50.300 314 495 1.2E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 SUPERFAMILY SSF52540 309 564 1.68E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 SMART SM00464 9 199 1.0E-19 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 692 700 - T 06-07-2017 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 SUPERFAMILY SSF88697 9 197 1.19E-22 T 06-07-2017 IPR015947 PUA-like domain SMD11_RS11010 cb5bce28e70d545b6b7217e2004d1bf2 800 TIGRFAM TIGR00763 lon: endopeptidase La 11 786 3.8E-235 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 SMD11_RS22640 8495fbb1e985083fc05e3a513dbcb2e7 274 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 227 243 3.4E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS22640 8495fbb1e985083fc05e3a513dbcb2e7 274 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 213 227 3.4E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS22640 8495fbb1e985083fc05e3a513dbcb2e7 274 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 243 255 3.4E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS22640 8495fbb1e985083fc05e3a513dbcb2e7 274 Pfam PF00196 Bacterial regulatory proteins, luxR family 213 265 3.0E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS22640 8495fbb1e985083fc05e3a513dbcb2e7 274 Gene3D G3DSA:1.10.10.10 209 272 1.9E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS22640 8495fbb1e985083fc05e3a513dbcb2e7 274 SUPERFAMILY SSF46894 207 273 1.9E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS22640 8495fbb1e985083fc05e3a513dbcb2e7 274 SMART SM00421 210 267 3.0E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS01860 3ab8cb9cbdc48f91c50d4ef9c9e63ec3 79 Gene3D G3DSA:1.10.1200.10 19 71 3.9E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01860 3ab8cb9cbdc48f91c50d4ef9c9e63ec3 79 Pfam PF00550 Phosphopantetheine attachment site 20 72 4.1E-6 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01860 3ab8cb9cbdc48f91c50d4ef9c9e63ec3 79 SUPERFAMILY SSF47336 19 72 4.19E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS16020 dfaa71fe831e7738b0c733da356ee6d3 487 SUPERFAMILY SSF46785 34 103 5.2E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16020 dfaa71fe831e7738b0c733da356ee6d3 487 Pfam PF00392 Bacterial regulatory proteins, gntR family 37 94 4.9E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS16020 dfaa71fe831e7738b0c733da356ee6d3 487 SMART SM00345 35 94 5.5E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS16020 dfaa71fe831e7738b0c733da356ee6d3 487 Pfam PF00155 Aminotransferase class I and II 139 418 1.1E-10 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS16020 dfaa71fe831e7738b0c733da356ee6d3 487 Gene3D G3DSA:1.10.10.10 35 98 1.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16020 dfaa71fe831e7738b0c733da356ee6d3 487 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 68 2.5E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS16020 dfaa71fe831e7738b0c733da356ee6d3 487 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 68 84 2.5E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS16020 dfaa71fe831e7738b0c733da356ee6d3 487 Gene3D G3DSA:3.40.640.10 155 363 5.0E-40 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS16020 dfaa71fe831e7738b0c733da356ee6d3 487 SUPERFAMILY SSF53383 113 471 1.9E-70 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS20805 aecd8bc4dac02bd41128cd92039fe3ef 246 SMART SM00448 30 143 2.4E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS20805 aecd8bc4dac02bd41128cd92039fe3ef 246 Pfam PF00196 Bacterial regulatory proteins, luxR family 182 237 4.5E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20805 aecd8bc4dac02bd41128cd92039fe3ef 246 SUPERFAMILY SSF52172 29 161 3.13E-36 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS20805 aecd8bc4dac02bd41128cd92039fe3ef 246 Gene3D G3DSA:1.10.10.10 150 244 8.5E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20805 aecd8bc4dac02bd41128cd92039fe3ef 246 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 213 7.7E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20805 aecd8bc4dac02bd41128cd92039fe3ef 246 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 213 225 7.7E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20805 aecd8bc4dac02bd41128cd92039fe3ef 246 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 197 7.7E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20805 aecd8bc4dac02bd41128cd92039fe3ef 246 SMART SM00421 180 237 3.2E-28 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20805 aecd8bc4dac02bd41128cd92039fe3ef 246 Gene3D G3DSA:3.40.50.2300 27 149 4.0E-38 T 06-07-2017 SMD11_RS20805 aecd8bc4dac02bd41128cd92039fe3ef 246 Pfam PF00072 Response regulator receiver domain 32 143 1.8E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS20805 aecd8bc4dac02bd41128cd92039fe3ef 246 ProSitePatterns PS00622 LuxR-type HTH domain signature. 197 224 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20805 aecd8bc4dac02bd41128cd92039fe3ef 246 SUPERFAMILY SSF46894 166 243 3.74E-24 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS23985 6034e223b3609d30eedbc4b0b9db9ca9 388 SUPERFAMILY SSF56112 95 308 4.93E-11 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS23985 6034e223b3609d30eedbc4b0b9db9ca9 388 SUPERFAMILY SSF56112 19 67 4.93E-11 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS07460 5ebe87a69b8a386a5cda4bea5d7b5786 220 Pfam PF00072 Response regulator receiver domain 25 115 2.2E-5 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS07460 5ebe87a69b8a386a5cda4bea5d7b5786 220 Gene3D G3DSA:3.40.50.2300 19 116 2.5E-9 T 06-07-2017 SMD11_RS07460 5ebe87a69b8a386a5cda4bea5d7b5786 220 SUPERFAMILY SSF52172 16 120 1.99E-11 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS07460 5ebe87a69b8a386a5cda4bea5d7b5786 220 SMART SM00421 156 213 1.0E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07460 5ebe87a69b8a386a5cda4bea5d7b5786 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07460 5ebe87a69b8a386a5cda4bea5d7b5786 220 Gene3D G3DSA:1.10.10.10 143 218 1.9E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07460 5ebe87a69b8a386a5cda4bea5d7b5786 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 2.8E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07460 5ebe87a69b8a386a5cda4bea5d7b5786 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 2.8E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07460 5ebe87a69b8a386a5cda4bea5d7b5786 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 2.8E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07460 5ebe87a69b8a386a5cda4bea5d7b5786 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 213 2.5E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07460 5ebe87a69b8a386a5cda4bea5d7b5786 220 SUPERFAMILY SSF46894 146 219 1.73E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 SUPERFAMILY SSF51905 5 305 3.53E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 1.3E-36 T 06-07-2017 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 1.3E-36 T 06-07-2017 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.3E-36 T 06-07-2017 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 1.3E-36 T 06-07-2017 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.3E-36 T 06-07-2017 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 Gene3D G3DSA:3.50.50.60 111 300 1.9E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 295 2.3E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 306 9.2E-122 T 06-07-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 Gene3D G3DSA:3.50.50.60 5 110 5.5E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 3.9E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 3.9E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 3.9E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 3.9E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 3.9E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 3.9E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 40 55 3.9E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 3.9E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 3.9E-80 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS16850 bbaabdf13ac3d47a368e069448ac02be 322 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 06-07-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 SMD11_RS04540 c446b065edf26932d90dba4f482803d2 377 SUPERFAMILY SSF55031 172 274 1.57E-20 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS04540 c446b065edf26932d90dba4f482803d2 377 Pfam PF01546 Peptidase family M20/M25/M40 90 341 1.7E-8 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD11_RS04540 c446b065edf26932d90dba4f482803d2 377 SUPERFAMILY SSF53187 283 371 1.19E-59 T 06-07-2017 SMD11_RS04540 c446b065edf26932d90dba4f482803d2 377 SUPERFAMILY SSF53187 12 183 1.19E-59 T 06-07-2017 SMD11_RS04540 c446b065edf26932d90dba4f482803d2 377 Gene3D G3DSA:3.40.630.10 6 171 3.3E-65 T 06-07-2017 SMD11_RS04540 c446b065edf26932d90dba4f482803d2 377 Gene3D G3DSA:3.40.630.10 280 373 3.3E-65 T 06-07-2017 SMD11_RS04540 c446b065edf26932d90dba4f482803d2 377 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 24 342 3.9E-63 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 SMD11_RS04540 c446b065edf26932d90dba4f482803d2 377 PIRSF PIRSF037226 1 377 6.4E-127 T 06-07-2017 IPR017144 Peptidase M20A, amidohydrolase, predicted SMD11_RS04540 c446b065edf26932d90dba4f482803d2 377 Pfam PF07687 Peptidase dimerisation domain 174 263 1.3E-10 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS04540 c446b065edf26932d90dba4f482803d2 377 Gene3D G3DSA:3.30.70.360 172 274 1.6E-24 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS23830 9df4836ac974b1fb8b6ee468656c507c 531 SUPERFAMILY SSF50494 29 253 1.87E-27 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS23830 9df4836ac974b1fb8b6ee468656c507c 531 Pfam PF00089 Trypsin 32 249 6.5E-22 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD11_RS23830 9df4836ac974b1fb8b6ee468656c507c 531 Gene3D G3DSA:2.40.10.10 32 65 1.3E-5 T 06-07-2017 SMD11_RS23830 9df4836ac974b1fb8b6ee468656c507c 531 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 58 73 6.0E-8 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD11_RS23830 9df4836ac974b1fb8b6ee468656c507c 531 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 192 204 6.0E-8 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD11_RS23830 9df4836ac974b1fb8b6ee468656c507c 531 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 118 132 6.0E-8 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD11_RS23830 9df4836ac974b1fb8b6ee468656c507c 531 Gene3D G3DSA:2.40.10.10 66 253 5.1E-18 T 06-07-2017 SMD11_RS23830 9df4836ac974b1fb8b6ee468656c507c 531 SMART SM00020 30 249 5.5E-8 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD11_RS13945 3c603271c4fe169a1cc7d00969058d47 81 Pfam PF11662 Protein of unknown function (DUF3263) 10 81 3.1E-33 T 06-07-2017 IPR021678 Protein of unknown function DUF3263 SMD11_RS30610 04c77bdc7a96305a4232e7655ecb2a00 352 SUPERFAMILY SSF53300 12 128 3.34E-8 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS30610 04c77bdc7a96305a4232e7655ecb2a00 352 Gene3D G3DSA:3.40.50.410 12 127 3.7E-5 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 SUPERFAMILY SSF50465 305 397 4.6E-36 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 Gene3D G3DSA:3.40.50.300 4 210 5.7E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 Pfam PF03144 Elongation factor Tu domain 2 227 295 1.2E-16 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 1.7E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.7E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 1.7E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 1.7E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 1.7E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 58.764 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 1.8E-33 T 06-07-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 SUPERFAMILY SSF50447 207 304 1.26E-30 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 Gene3D G3DSA:2.40.30.10 303 395 3.8E-46 T 06-07-2017 SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 2.8E-14 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 Gene3D G3DSA:2.40.30.10 211 301 2.1E-36 T 06-07-2017 SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 9.0E-57 T 06-07-2017 SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 395 1.6E-218 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SMD11_RS18870 60781bc5bd00376e99b2bc43f7f8cdc7 397 SUPERFAMILY SSF52540 9 228 1.77E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28660 e3dc9435a0014c1efc0970d8476ceea8 463 Pfam PF00583 Acetyltransferase (GNAT) family 351 418 2.5E-6 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS28660 e3dc9435a0014c1efc0970d8476ceea8 463 Gene3D G3DSA:3.40.630.30 285 418 6.4E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS28660 e3dc9435a0014c1efc0970d8476ceea8 463 Gene3D G3DSA:3.30.70.260 101 157 7.0E-4 T 06-07-2017 SMD11_RS28660 e3dc9435a0014c1efc0970d8476ceea8 463 SUPERFAMILY SSF55729 270 418 2.84E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 SUPERFAMILY SSF52777 22 196 6.78E-30 T 06-07-2017 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1687 1698 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 ProSitePatterns PS00455 Putative AMP-binding domain signature. 618 629 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 SUPERFAMILY SSF52777 202 434 1.67E-43 T 06-07-2017 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 SUPERFAMILY SSF52777 1263 1504 2.67E-62 T 06-07-2017 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 SUPERFAMILY SSF47336 983 1093 1.44E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Pfam PF00501 AMP-binding enzyme 475 883 4.1E-86 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Pfam PF00501 AMP-binding enzyme 1543 1954 2.9E-101 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Gene3D G3DSA:3.40.50.1820 2330 2399 3.3E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Gene3D G3DSA:3.40.50.1820 2131 2257 3.3E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 SUPERFAMILY SSF53474 2129 2396 4.92E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Gene3D G3DSA:3.40.50.980 468 628 1.0E-42 T 06-07-2017 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Gene3D G3DSA:3.40.50.980 1534 1695 7.6E-51 T 06-07-2017 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2085 2100 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Pfam PF13745 HxxPF-repeated domain 1395 1486 4.0E-31 T 06-07-2017 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 496 907 1.6E-114 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1563 1978 2.3E-138 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Gene3D G3DSA:3.40.50.980 629 783 1.9E-27 T 06-07-2017 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Gene3D G3DSA:3.40.50.980 1696 1851 2.5E-49 T 06-07-2017 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Gene3D G3DSA:1.10.1200.10 993 1060 1.2E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Gene3D G3DSA:1.10.1200.10 2066 2130 2.5E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 SMART SM00823 Phosphopantetheine attachment site 990 1060 8.6E-5 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 SMART SM00823 Phosphopantetheine attachment site 2061 2130 0.0012 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 SUPERFAMILY SSF56801 1500 2074 3.27E-164 T 06-07-2017 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 SUPERFAMILY SSF52777 1082 1249 2.67E-44 T 06-07-2017 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Pfam PF13193 AMP-binding enzyme C-terminal domain 1962 2035 1.3E-15 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Pfam PF13193 AMP-binding enzyme C-terminal domain 891 965 7.1E-15 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 SUPERFAMILY SSF56801 463 1003 3.4E-138 T 06-07-2017 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 SUPERFAMILY SSF47336 2054 2126 1.02E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Pfam PF00550 Phosphopantetheine attachment site 992 1056 5.7E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Pfam PF00550 Phosphopantetheine attachment site 2062 2122 2.9E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Pfam PF00975 Thioesterase domain 2151 2312 4.0E-28 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Pfam PF00668 Condensation domain 1078 1373 8.6E-59 T 06-07-2017 IPR001242 Condensation domain SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Pfam PF00668 Condensation domain 17 312 1.8E-42 T 06-07-2017 IPR001242 Condensation domain SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Gene3D G3DSA:3.30.300.30 1949 2065 3.9E-41 T 06-07-2017 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Gene3D G3DSA:3.30.300.30 878 992 2.4E-38 T 06-07-2017 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Gene3D G3DSA:2.30.38.10 1860 1943 2.4E-24 T 06-07-2017 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 Gene3D G3DSA:2.30.38.10 790 873 4.4E-25 T 06-07-2017 SMD11_RS04535 32af0dc87994c435c4fb3b1df9c1b68c 2401 SMART SM00824 Thioesterase 2153 2396 3.9E-6 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD11_RS03950 19f6b0e75877afd202b55ae3728cc538 324 PIRSF PIRSF018005 5 320 8.9E-133 T 06-07-2017 IPR017804 Methyltransferase EgtD-like SMD11_RS03950 19f6b0e75877afd202b55ae3728cc538 324 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 190 314 2.0E-40 T 06-07-2017 IPR019257 Histidine-specific methyltransferase, SAM-dependent SMD11_RS03950 19f6b0e75877afd202b55ae3728cc538 324 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 6 319 55.907 T 06-07-2017 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 SMD11_RS03950 19f6b0e75877afd202b55ae3728cc538 324 SUPERFAMILY SSF53335 282 311 1.32E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS03950 19f6b0e75877afd202b55ae3728cc538 324 SUPERFAMILY SSF53335 26 192 1.32E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS03950 19f6b0e75877afd202b55ae3728cc538 324 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 19 316 1.6E-111 T 06-07-2017 IPR017804 Methyltransferase EgtD-like SMD11_RS03950 19f6b0e75877afd202b55ae3728cc538 324 Gene3D G3DSA:3.40.50.150 45 212 1.2E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS03950 19f6b0e75877afd202b55ae3728cc538 324 Gene3D G3DSA:3.40.50.150 279 306 1.2E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 Pfam PF13368 Topoisomerase C-terminal repeat 703 766 7.1E-13 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 Pfam PF13368 Topoisomerase C-terminal repeat 773 823 3.1E-15 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 Pfam PF13368 Topoisomerase C-terminal repeat 644 695 6.9E-8 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 Pfam PF13368 Topoisomerase C-terminal repeat 836 888 6.0E-20 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 SMART SM00437 289 556 8.9E-121 T 06-07-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 326 340 - T 06-07-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 Gene3D G3DSA:2.70.20.10 206 355 2.0E-27 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 Gene3D G3DSA:2.70.20.10 356 502 1.1E-34 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 SMART SM00436 126 214 2.1E-45 T 06-07-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 Gene3D G3DSA:1.10.460.10 503 597 1.7E-50 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 Gene3D G3DSA:1.10.460.10 157 204 1.7E-50 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 14 664 1.5E-242 T 06-07-2017 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 Hamap MF_00952 DNA topoisomerase 1 [topA]. 12 782 55.708 T 06-07-2017 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 331 340 1.1E-33 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 184 202 1.1E-33 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 519 533 1.1E-33 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 1.1E-33 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 408 424 1.1E-33 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 Pfam PF01131 DNA topoisomerase 150 593 3.3E-129 T 06-07-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 SUPERFAMILY SSF56712 12 597 4.45E-180 T 06-07-2017 IPR023405 DNA topoisomerase, type IA, core domain SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 SMART SM00493 12 126 2.5E-38 T 06-07-2017 IPR006171 Toprim domain SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 Pfam PF01751 Toprim domain 14 135 1.9E-28 T 06-07-2017 IPR006171 Toprim domain SMD11_RS15275 d3d05c75da5ad6c0a02dfcfe51815b27 959 Gene3D G3DSA:3.40.50.140 12 156 4.9E-49 T 06-07-2017 IPR006171 Toprim domain SMD11_RS14015 b37c90a32e261444f493d40937576a7e 234 Gene3D G3DSA:1.10.357.10 28 215 1.7E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS14015 b37c90a32e261444f493d40937576a7e 234 SUPERFAMILY SSF48498 103 207 1.89E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS14015 b37c90a32e261444f493d40937576a7e 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 82 1.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS14015 b37c90a32e261444f493d40937576a7e 234 SUPERFAMILY SSF46689 27 106 5.99E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS32310 08d99a6761c936420ce8a395d8b44f4e 345 Gene3D G3DSA:3.40.50.720 5 206 4.4E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32310 08d99a6761c936420ce8a395d8b44f4e 345 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 332 49.769 T 06-07-2017 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 SMD11_RS32310 08d99a6761c936420ce8a395d8b44f4e 345 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 322 7.9E-118 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32310 08d99a6761c936420ce8a395d8b44f4e 345 SUPERFAMILY SSF51735 3 328 2.32E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32310 08d99a6761c936420ce8a395d8b44f4e 345 Gene3D G3DSA:3.90.25.10 207 333 5.6E-46 T 06-07-2017 SMD11_RS17950 cee735f90b7f0c764617ce9600f15470 368 SUPERFAMILY SSF53223 24 157 7.68E-44 T 06-07-2017 SMD11_RS17950 cee735f90b7f0c764617ce9600f15470 368 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 79 93 2.0E-20 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 SMD11_RS17950 cee735f90b7f0c764617ce9600f15470 368 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 301 312 2.0E-20 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 SMD11_RS17950 cee735f90b7f0c764617ce9600f15470 368 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 189 209 2.0E-20 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 SMD11_RS17950 cee735f90b7f0c764617ce9600f15470 368 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 145 167 2.0E-20 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 SMD11_RS17950 cee735f90b7f0c764617ce9600f15470 368 SMART SM00839 157 364 5.9E-46 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 SMD11_RS17950 cee735f90b7f0c764617ce9600f15470 368 Gene3D G3DSA:3.40.50.720 161 351 7.5E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17950 cee735f90b7f0c764617ce9600f15470 368 Gene3D G3DSA:3.40.192.10 20 160 8.1E-63 T 06-07-2017 SMD11_RS17950 cee735f90b7f0c764617ce9600f15470 368 PIRSF PIRSF000188 14 366 4.0E-142 T 06-07-2017 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 SMD11_RS17950 cee735f90b7f0c764617ce9600f15470 368 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 31 142 2.3E-24 T 06-07-2017 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 SMD11_RS17950 cee735f90b7f0c764617ce9600f15470 368 SUPERFAMILY SSF51735 154 362 2.26E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17950 cee735f90b7f0c764617ce9600f15470 368 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 223 310 1.2E-8 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 SMD11_RS17950 cee735f90b7f0c764617ce9600f15470 368 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 87 100 - T 06-07-2017 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-70614 SMD11_RS18760 9851d6304aab68d071af38c0907aea86 423 SUPERFAMILY SSF51556 78 363 1.05E-40 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS18760 9851d6304aab68d071af38c0907aea86 423 Gene3D G3DSA:2.30.40.10 19 110 1.6E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS18760 9851d6304aab68d071af38c0907aea86 423 SUPERFAMILY SSF51338 356 384 2.8E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS18760 9851d6304aab68d071af38c0907aea86 423 SUPERFAMILY SSF51338 28 75 2.8E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS18760 9851d6304aab68d071af38c0907aea86 423 Gene3D G3DSA:3.20.20.140 111 354 7.9E-52 T 06-07-2017 SMD11_RS18760 9851d6304aab68d071af38c0907aea86 423 Pfam PF07969 Amidohydrolase family 185 392 2.0E-10 T 06-07-2017 IPR013108 Amidohydrolase 3 SMD11_RS08635 43d696006c866d077cac6e9c4839c5fd 455 Pfam PF00675 Insulinase (Peptidase family M16) 34 158 8.8E-10 T 06-07-2017 IPR011765 Peptidase M16, N-terminal SMD11_RS08635 43d696006c866d077cac6e9c4839c5fd 455 SUPERFAMILY SSF63411 247 445 9.43E-21 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMD11_RS08635 43d696006c866d077cac6e9c4839c5fd 455 Gene3D G3DSA:3.30.830.10 241 434 2.5E-10 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 SMD11_RS08635 43d696006c866d077cac6e9c4839c5fd 455 Pfam PF05193 Peptidase M16 inactive domain 185 368 7.5E-20 T 06-07-2017 IPR007863 Peptidase M16, C-terminal SMD11_RS08635 43d696006c866d077cac6e9c4839c5fd 455 Gene3D G3DSA:3.30.830.10 21 231 1.1E-34 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 SMD11_RS08635 43d696006c866d077cac6e9c4839c5fd 455 SUPERFAMILY SSF63411 7 239 8.62E-40 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMD11_RS21915 ecc3ee62a75f81336cd3b100265e7492 561 Gene3D G3DSA:1.10.1740.10 12 112 1.3E-23 T 06-07-2017 SMD11_RS21915 ecc3ee62a75f81336cd3b100265e7492 561 Gene3D G3DSA:3.40.33.10 439 553 1.6E-12 T 06-07-2017 IPR014044 CAP domain SMD11_RS21915 ecc3ee62a75f81336cd3b100265e7492 561 SUPERFAMILY SSF88946 11 101 1.51E-21 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS21915 ecc3ee62a75f81336cd3b100265e7492 561 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 50 81 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS21915 ecc3ee62a75f81336cd3b100265e7492 561 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 185 2.7E-22 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS21915 ecc3ee62a75f81336cd3b100265e7492 561 Pfam PF00188 Cysteine-rich secretory protein family 444 558 6.1E-21 T 06-07-2017 IPR014044 CAP domain SMD11_RS21915 ecc3ee62a75f81336cd3b100265e7492 561 SUPERFAMILY SSF55797 438 558 2.2E-23 T 06-07-2017 IPR014044 CAP domain SMD11_RS21915 ecc3ee62a75f81336cd3b100265e7492 561 Pfam PF04542 Sigma-70 region 2 28 93 6.1E-15 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS10800 55ac8e6e4af4ff6a058f73c3c0587845 271 Gene3D G3DSA:1.10.520.20 110 184 1.3E-4 T 06-07-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 SMD11_RS10800 55ac8e6e4af4ff6a058f73c3c0587845 271 PRINTS PR00125 ATP synthase delta subunit signature 244 262 2.8E-8 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 SMD11_RS10800 55ac8e6e4af4ff6a058f73c3c0587845 271 PRINTS PR00125 ATP synthase delta subunit signature 229 244 2.8E-8 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 SMD11_RS10800 55ac8e6e4af4ff6a058f73c3c0587845 271 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 111 267 6.1E-20 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 SMD11_RS10800 55ac8e6e4af4ff6a058f73c3c0587845 271 Pfam PF00213 ATP synthase delta (OSCP) subunit 110 267 3.6E-33 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 SMD11_RS10800 55ac8e6e4af4ff6a058f73c3c0587845 271 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 231 250 - T 06-07-2017 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210 SMD11_RS10800 55ac8e6e4af4ff6a058f73c3c0587845 271 Hamap MF_01416 ATP synthase subunit delta [atpD]. 94 271 14.885 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 SMD11_RS16330 8dbbc16ad22e2a1aa24dcd216a72b254 294 SUPERFAMILY SSF46785 2 86 9.09E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16330 8dbbc16ad22e2a1aa24dcd216a72b254 294 Gene3D G3DSA:3.40.190.10 174 265 4.3E-20 T 06-07-2017 SMD11_RS16330 8dbbc16ad22e2a1aa24dcd216a72b254 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.9E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS16330 8dbbc16ad22e2a1aa24dcd216a72b254 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.9E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS16330 8dbbc16ad22e2a1aa24dcd216a72b254 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.9E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS16330 8dbbc16ad22e2a1aa24dcd216a72b254 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.9E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS16330 8dbbc16ad22e2a1aa24dcd216a72b254 294 Pfam PF03466 LysR substrate binding domain 87 292 6.4E-27 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS16330 8dbbc16ad22e2a1aa24dcd216a72b254 294 Gene3D G3DSA:1.10.10.10 2 84 4.0E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16330 8dbbc16ad22e2a1aa24dcd216a72b254 294 SUPERFAMILY SSF53850 86 292 1.75E-24 T 06-07-2017 SMD11_RS16330 8dbbc16ad22e2a1aa24dcd216a72b254 294 Gene3D G3DSA:3.40.190.10 89 173 7.3E-19 T 06-07-2017 SMD11_RS31315 1935d430697702217e123aa3ce7274c7 483 PIRSF PIRSF006060 1 481 1.0E-52 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS31315 1935d430697702217e123aa3ce7274c7 483 ProSitePatterns PS00218 Amino acid permeases signature. 41 72 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD11_RS31315 1935d430697702217e123aa3ce7274c7 483 Pfam PF13520 Amino acid permease 14 448 4.2E-58 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS14305 a4232bd655d061d990a72a02cf228985 409 SMART SM01209 114 289 2.2E-4 T 06-07-2017 SMD11_RS14305 a4232bd655d061d990a72a02cf228985 409 Pfam PF13535 ATP-grasp domain 150 292 5.8E-18 T 06-07-2017 SMD11_RS14305 a4232bd655d061d990a72a02cf228985 409 Gene3D G3DSA:3.30.470.20 108 398 9.8E-35 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS14305 a4232bd655d061d990a72a02cf228985 409 SUPERFAMILY SSF56059 96 326 2.47E-38 T 06-07-2017 SMD11_RS00505 d8fcd4ec1aa7882ddc5f548a94f55fd1 565 SUPERFAMILY SSF90123 3 294 8.63E-11 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS00505 d8fcd4ec1aa7882ddc5f548a94f55fd1 565 Gene3D G3DSA:3.40.50.300 322 552 9.2E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00505 d8fcd4ec1aa7882ddc5f548a94f55fd1 565 SUPERFAMILY SSF52540 322 562 4.7E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00505 d8fcd4ec1aa7882ddc5f548a94f55fd1 565 SMART SM00382 349 539 8.6E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS00505 d8fcd4ec1aa7882ddc5f548a94f55fd1 565 Gene3D G3DSA:1.20.1560.10 2 293 1.4E-7 T 06-07-2017 SMD11_RS00505 d8fcd4ec1aa7882ddc5f548a94f55fd1 565 Pfam PF00005 ABC transporter 340 493 2.5E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS00505 d8fcd4ec1aa7882ddc5f548a94f55fd1 565 ProSitePatterns PS00211 ABC transporters family signature. 465 479 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS28805 1a4777c7c9a4f59da63b13d532b084fd 100 Pfam PF00547 Urease, gamma subunit 1 99 3.3E-46 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28805 1a4777c7c9a4f59da63b13d532b084fd 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 33.348 T 06-07-2017 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28805 1a4777c7c9a4f59da63b13d532b084fd 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 2.0E-33 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28805 1a4777c7c9a4f59da63b13d532b084fd 100 SUPERFAMILY SSF54111 1 99 1.7E-44 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28805 1a4777c7c9a4f59da63b13d532b084fd 100 PIRSF PIRSF001223 1 100 4.7E-50 T 06-07-2017 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28805 1a4777c7c9a4f59da63b13d532b084fd 100 Gene3D G3DSA:3.30.280.10 1 99 8.1E-48 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS28805 1a4777c7c9a4f59da63b13d532b084fd 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 6.6E-48 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 SMD11_RS08680 d3f2528b6ca6658da2e262bb22f66440 285 Pfam PF00005 ABC transporter 39 177 3.2E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS08680 d3f2528b6ca6658da2e262bb22f66440 285 SMART SM00382 47 232 4.9E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS08680 d3f2528b6ca6658da2e262bb22f66440 285 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS08680 d3f2528b6ca6658da2e262bb22f66440 285 SUPERFAMILY SSF52540 18 252 1.11E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08680 d3f2528b6ca6658da2e262bb22f66440 285 Gene3D G3DSA:3.40.50.300 14 231 7.1E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25170 e7d5fda2d68326538befe4e3c1d588d0 695 SUPERFAMILY SSF52518 358 553 7.5E-63 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS25170 e7d5fda2d68326538befe4e3c1d588d0 695 TIGRFAM TIGR00232 tktlase_bact: transketolase 19 685 3.2E-236 T 06-07-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 SMD11_RS25170 e7d5fda2d68326538befe4e3c1d588d0 695 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 16 355 1.9E-135 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS25170 e7d5fda2d68326538befe4e3c1d588d0 695 Pfam PF02780 Transketolase, C-terminal domain 573 679 1.3E-12 T 06-07-2017 IPR033248 Transketolase, C-terminal domain SMD11_RS25170 e7d5fda2d68326538befe4e3c1d588d0 695 Gene3D G3DSA:3.40.50.970 13 341 1.3E-111 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS25170 e7d5fda2d68326538befe4e3c1d588d0 695 ProSitePatterns PS00802 Transketolase signature 2. 491 507 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS25170 e7d5fda2d68326538befe4e3c1d588d0 695 Gene3D G3DSA:3.40.50.970 351 561 4.0E-72 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS25170 e7d5fda2d68326538befe4e3c1d588d0 695 SMART SM00861 371 552 9.3E-64 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS25170 e7d5fda2d68326538befe4e3c1d588d0 695 SUPERFAMILY SSF52922 557 688 1.7E-40 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS25170 e7d5fda2d68326538befe4e3c1d588d0 695 Gene3D G3DSA:3.40.50.920 562 688 2.4E-48 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS25170 e7d5fda2d68326538befe4e3c1d588d0 695 Pfam PF02779 Transketolase, pyrimidine binding domain 370 551 3.5E-44 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS25170 e7d5fda2d68326538befe4e3c1d588d0 695 ProSitePatterns PS00801 Transketolase signature 1. 24 44 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS25170 e7d5fda2d68326538befe4e3c1d588d0 695 SUPERFAMILY SSF52518 6 341 4.55E-103 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS30930 11ed124693dbbb01db82d8809add98cf 504 Gene3D G3DSA:3.40.50.300 272 480 1.9E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30930 11ed124693dbbb01db82d8809add98cf 504 SUPERFAMILY SSF52540 9 229 2.61E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30930 11ed124693dbbb01db82d8809add98cf 504 SUPERFAMILY SSF52540 271 479 1.03E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30930 11ed124693dbbb01db82d8809add98cf 504 Gene3D G3DSA:3.40.50.300 8 228 4.5E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30930 11ed124693dbbb01db82d8809add98cf 504 Pfam PF00005 ABC transporter 272 425 2.7E-13 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS30930 11ed124693dbbb01db82d8809add98cf 504 Pfam PF00005 ABC transporter 26 172 1.7E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS30930 11ed124693dbbb01db82d8809add98cf 504 ProSitePatterns PS00211 ABC transporters family signature. 397 411 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS30930 11ed124693dbbb01db82d8809add98cf 504 SMART SM00382 35 220 9.9E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS30930 11ed124693dbbb01db82d8809add98cf 504 SMART SM00382 278 483 17.0 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS24020 caa16fabef121afe4f04f3ee85d9092b 226 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 1 211 5.0E-81 T 06-07-2017 SMD11_RS24020 caa16fabef121afe4f04f3ee85d9092b 226 Pfam PF13829 Domain of unknown function (DUF4191) 8 224 3.2E-82 T 06-07-2017 IPR025445 Protein of unknown function DUF4191 SMD11_RS27860 f5eaa6a0b8f0fcf1c87e0caac9190875 584 Pfam PF00795 Carbon-nitrogen hydrolase 311 540 2.2E-19 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS27860 f5eaa6a0b8f0fcf1c87e0caac9190875 584 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 94 518 1.2E-70 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 SMD11_RS27860 f5eaa6a0b8f0fcf1c87e0caac9190875 584 Gene3D G3DSA:3.60.110.10 275 548 6.3E-34 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS27860 f5eaa6a0b8f0fcf1c87e0caac9190875 584 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 42 556 16.485 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 SMD11_RS27860 f5eaa6a0b8f0fcf1c87e0caac9190875 584 SUPERFAMILY SSF56317 278 547 7.72E-41 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS04920 331d007aad94b194d0af862e8edd9b66 462 SUPERFAMILY SSF53383 41 462 4.35E-106 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS04920 331d007aad94b194d0af862e8edd9b66 462 Gene3D G3DSA:3.90.1150.10 42 99 8.6E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS04920 331d007aad94b194d0af862e8edd9b66 462 Gene3D G3DSA:3.90.1150.10 370 461 8.6E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS04920 331d007aad94b194d0af862e8edd9b66 462 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 279 316 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS04920 331d007aad94b194d0af862e8edd9b66 462 Pfam PF00202 Aminotransferase class-III 67 459 8.2E-87 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS04920 331d007aad94b194d0af862e8edd9b66 462 Gene3D G3DSA:3.40.640.10 100 367 1.0E-70 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS15635 3afb155a6cc24007783ff624db8dcd40 783 Gene3D G3DSA:1.10.8.60 168 245 1.3E-20 T 06-07-2017 SMD11_RS15635 3afb155a6cc24007783ff624db8dcd40 783 Gene3D G3DSA:3.40.50.300 15 167 1.4E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15635 3afb155a6cc24007783ff624db8dcd40 783 SUPERFAMILY SSF48019 247 365 1.11E-21 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 SMD11_RS15635 3afb155a6cc24007783ff624db8dcd40 783 SUPERFAMILY SSF52540 32 223 9.3E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15635 3afb155a6cc24007783ff624db8dcd40 783 Gene3D G3DSA:1.20.272.10 246 364 3.2E-14 T 06-07-2017 SMD11_RS15635 3afb155a6cc24007783ff624db8dcd40 783 Pfam PF13177 DNA polymerase III, delta subunit 20 178 1.5E-37 T 06-07-2017 SMD11_RS15635 3afb155a6cc24007783ff624db8dcd40 783 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 236 365 2.6E-12 T 06-07-2017 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 SMD11_RS15635 3afb155a6cc24007783ff624db8dcd40 783 SMART SM00382 37 181 5.5E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS15635 3afb155a6cc24007783ff624db8dcd40 783 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 5 363 6.3E-117 T 06-07-2017 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 SMD11_RS06260 1603481e130d51a5d9b3f063e4e5b66a 272 Gene3D G3DSA:1.10.10.10 206 262 4.6E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06260 1603481e130d51a5d9b3f063e4e5b66a 272 SMART SM01012 203 258 1.8E-16 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 SMD11_RS06260 1603481e130d51a5d9b3f063e4e5b66a 272 Pfam PF03861 ANTAR domain 205 258 1.7E-15 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 SMD11_RS06260 1603481e130d51a5d9b3f063e4e5b66a 272 SUPERFAMILY SSF52172 195 258 4.42E-8 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS06260 1603481e130d51a5d9b3f063e4e5b66a 272 SUPERFAMILY SSF55781 63 199 1.18E-6 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS07540 eae8dc35d2f83be15e92d314548b19a3 353 Pfam PF13407 Periplasmic binding protein domain 30 290 3.2E-64 T 06-07-2017 IPR025997 Periplasmic binding protein SMD11_RS07540 eae8dc35d2f83be15e92d314548b19a3 353 SUPERFAMILY SSF53822 28 326 4.54E-61 T 06-07-2017 IPR028082 Periplasmic binding protein-like I SMD11_RS07540 eae8dc35d2f83be15e92d314548b19a3 353 Gene3D G3DSA:3.40.50.2300 144 326 7.7E-37 T 06-07-2017 SMD11_RS07540 eae8dc35d2f83be15e92d314548b19a3 353 Gene3D G3DSA:3.40.50.2300 29 143 2.1E-25 T 06-07-2017 SMD11_RS29725 ef2bd53abcdd46d829229950fbc84a78 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 4.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29725 ef2bd53abcdd46d829229950fbc84a78 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 4.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29725 ef2bd53abcdd46d829229950fbc84a78 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 4.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29725 ef2bd53abcdd46d829229950fbc84a78 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 4.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29725 ef2bd53abcdd46d829229950fbc84a78 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 4.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29725 ef2bd53abcdd46d829229950fbc84a78 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 4.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29725 ef2bd53abcdd46d829229950fbc84a78 264 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 19 212 3.0E-4 T 06-07-2017 SMD11_RS29725 ef2bd53abcdd46d829229950fbc84a78 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS29725 ef2bd53abcdd46d829229950fbc84a78 264 SUPERFAMILY SSF51735 18 263 1.77E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29725 ef2bd53abcdd46d829229950fbc84a78 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 3.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29725 ef2bd53abcdd46d829229950fbc84a78 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 3.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29725 ef2bd53abcdd46d829229950fbc84a78 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 3.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29725 ef2bd53abcdd46d829229950fbc84a78 264 Gene3D G3DSA:3.40.50.720 14 263 1.1E-87 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29725 ef2bd53abcdd46d829229950fbc84a78 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 262 5.2E-69 T 06-07-2017 SMD11_RS27390 4ac92fef5449499bed6c3def1ea7026a 90 SMART SM01409 18 82 2.2E-14 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SMD11_RS27390 4ac92fef5449499bed6c3def1ea7026a 90 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 11 83 14.945 T 06-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS27390 4ac92fef5449499bed6c3def1ea7026a 90 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 12 80 8.5E-22 T 06-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS27390 4ac92fef5449499bed6c3def1ea7026a 90 Gene3D G3DSA:3.90.940.10 11 86 3.9E-34 T 06-07-2017 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SMD11_RS27390 4ac92fef5449499bed6c3def1ea7026a 90 Pfam PF01192 RNA polymerase Rpb6 18 80 9.7E-15 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SMD11_RS27390 4ac92fef5449499bed6c3def1ea7026a 90 SUPERFAMILY SSF63562 11 87 6.1E-25 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SMD11_RS05640 8efd06b9c08dae4d1f4bfb2a057cacf1 271 Pfam PF03704 Bacterial transcriptional activator domain 108 253 1.3E-42 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS05640 8efd06b9c08dae4d1f4bfb2a057cacf1 271 SUPERFAMILY SSF46894 2 75 1.11E-11 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS05640 8efd06b9c08dae4d1f4bfb2a057cacf1 271 Gene3D G3DSA:1.10.10.10 24 102 1.7E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05640 8efd06b9c08dae4d1f4bfb2a057cacf1 271 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 75 6.9E-7 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS05640 8efd06b9c08dae4d1f4bfb2a057cacf1 271 SUPERFAMILY SSF48452 103 262 4.93E-38 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS05640 8efd06b9c08dae4d1f4bfb2a057cacf1 271 Gene3D G3DSA:1.25.40.10 114 231 9.4E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS05640 8efd06b9c08dae4d1f4bfb2a057cacf1 271 SMART SM00862 15 101 2.5E-4 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS05640 8efd06b9c08dae4d1f4bfb2a057cacf1 271 SMART SM01043 108 253 3.1E-48 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS29060 22c1cbead36a82cb84029a95c02d7f37 601 SUPERFAMILY SSF48452 94 264 1.09E-30 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS29060 22c1cbead36a82cb84029a95c02d7f37 601 Pfam PF03704 Bacterial transcriptional activator domain 99 241 1.4E-37 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS29060 22c1cbead36a82cb84029a95c02d7f37 601 Gene3D G3DSA:1.10.10.10 17 95 9.7E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS29060 22c1cbead36a82cb84029a95c02d7f37 601 Gene3D G3DSA:3.40.50.300 310 402 3.3E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29060 22c1cbead36a82cb84029a95c02d7f37 601 SMART SM00862 14 92 7.6E-10 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS29060 22c1cbead36a82cb84029a95c02d7f37 601 SMART SM00382 310 447 0.0036 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS29060 22c1cbead36a82cb84029a95c02d7f37 601 SUPERFAMILY SSF52540 283 477 4.89E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29060 22c1cbead36a82cb84029a95c02d7f37 601 Gene3D G3DSA:3.40.50.300 187 219 6.1E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29060 22c1cbead36a82cb84029a95c02d7f37 601 SMART SM01043 99 241 1.7E-38 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS29060 22c1cbead36a82cb84029a95c02d7f37 601 PRINTS PR00364 Disease resistance protein signature 460 474 4.7E-7 T 06-07-2017 SMD11_RS29060 22c1cbead36a82cb84029a95c02d7f37 601 PRINTS PR00364 Disease resistance protein signature 313 328 4.7E-7 T 06-07-2017 SMD11_RS29060 22c1cbead36a82cb84029a95c02d7f37 601 PRINTS PR00364 Disease resistance protein signature 372 386 4.7E-7 T 06-07-2017 SMD11_RS29060 22c1cbead36a82cb84029a95c02d7f37 601 SUPERFAMILY SSF46894 2 92 2.55E-14 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS29060 22c1cbead36a82cb84029a95c02d7f37 601 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 91 2.2E-7 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS00460 6dd3905bf951edcbdf45a590f7e473c9 328 SUPERFAMILY SSF53850 91 314 4.26E-40 T 06-07-2017 SMD11_RS00460 6dd3905bf951edcbdf45a590f7e473c9 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS00460 6dd3905bf951edcbdf45a590f7e473c9 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS00460 6dd3905bf951edcbdf45a590f7e473c9 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS00460 6dd3905bf951edcbdf45a590f7e473c9 328 Gene3D G3DSA:3.40.190.10 90 212 2.5E-23 T 06-07-2017 SMD11_RS00460 6dd3905bf951edcbdf45a590f7e473c9 328 Gene3D G3DSA:1.10.10.10 1 83 6.3E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00460 6dd3905bf951edcbdf45a590f7e473c9 328 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.8E-24 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS00460 6dd3905bf951edcbdf45a590f7e473c9 328 Gene3D G3DSA:3.40.190.10 213 284 2.3E-10 T 06-07-2017 SMD11_RS00460 6dd3905bf951edcbdf45a590f7e473c9 328 SUPERFAMILY SSF46785 1 111 1.28E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00460 6dd3905bf951edcbdf45a590f7e473c9 328 Pfam PF03466 LysR substrate binding domain 200 310 3.6E-17 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS00460 6dd3905bf951edcbdf45a590f7e473c9 328 Pfam PF03466 LysR substrate binding domain 90 190 1.0E-22 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS27920 62df4f37d361b1b9c61ce905b0709bdd 522 SUPERFAMILY SSF56091 180 385 2.28E-47 T 06-07-2017 SMD11_RS27920 62df4f37d361b1b9c61ce905b0709bdd 522 Pfam PF04679 ATP dependent DNA ligase C terminal region 404 495 3.8E-14 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 SMD11_RS27920 62df4f37d361b1b9c61ce905b0709bdd 522 Pfam PF01068 ATP dependent DNA ligase domain 186 385 5.9E-43 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 SMD11_RS27920 62df4f37d361b1b9c61ce905b0709bdd 522 SUPERFAMILY SSF50249 387 506 1.29E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS27920 62df4f37d361b1b9c61ce905b0709bdd 522 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 208 216 - T 06-07-2017 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 SMD11_RS27920 62df4f37d361b1b9c61ce905b0709bdd 522 Gene3D G3DSA:2.40.50.140 401 508 1.1E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS27920 62df4f37d361b1b9c61ce905b0709bdd 522 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 68 507 9.2E-78 T 06-07-2017 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 SMD11_RS27920 62df4f37d361b1b9c61ce905b0709bdd 522 Pfam PF04675 DNA ligase N terminus 70 136 1.5E-7 T 06-07-2017 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 SMD11_RS27920 62df4f37d361b1b9c61ce905b0709bdd 522 Gene3D G3DSA:1.10.3260.10 69 183 4.3E-18 T 06-07-2017 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 SMD11_RS27920 62df4f37d361b1b9c61ce905b0709bdd 522 SUPERFAMILY SSF117018 4 202 8.37E-29 T 06-07-2017 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 SMD11_RS27920 62df4f37d361b1b9c61ce905b0709bdd 522 Gene3D G3DSA:3.30.470.30 213 327 1.6E-30 T 06-07-2017 SMD11_RS27920 62df4f37d361b1b9c61ce905b0709bdd 522 Gene3D G3DSA:3.30.1490.70 337 368 1.9E-17 T 06-07-2017 SMD11_RS27920 62df4f37d361b1b9c61ce905b0709bdd 522 Gene3D G3DSA:3.30.1490.70 184 212 1.9E-17 T 06-07-2017 SMD11_RS27920 62df4f37d361b1b9c61ce905b0709bdd 522 Gene3D G3DSA:2.40.50.140 369 400 2.7E-5 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS27920 62df4f37d361b1b9c61ce905b0709bdd 522 Hamap MF_00407 DNA ligase [lig]. 1 511 26.097 T 06-07-2017 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 SUPERFAMILY SSF88697 276 366 1.55E-21 T 06-07-2017 IPR015947 PUA-like domain SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 SMART SM00359 276 355 2.1E-16 T 06-07-2017 IPR002478 PUA domain GO:0003723 SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 PIRSF PIRSF000729 1 368 5.7E-121 T 06-07-2017 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 PRINTS PR00474 Glutamate 5-kinase family signature 44 58 1.3E-52 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 PRINTS PR00474 Glutamate 5-kinase family signature 211 231 1.3E-52 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 PRINTS PR00474 Glutamate 5-kinase family signature 118 139 1.3E-52 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 PRINTS PR00474 Glutamate 5-kinase family signature 150 177 1.3E-52 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 PRINTS PR00474 Glutamate 5-kinase family signature 78 106 1.3E-52 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 Pfam PF00696 Amino acid kinase family 6 237 2.8E-40 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 TIGRFAM TIGR01027 proB: glutamate 5-kinase 5 365 8.6E-125 T 06-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 Gene3D G3DSA:2.30.130.10 273 365 5.9E-25 T 06-07-2017 IPR015947 PUA-like domain SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 Pfam PF01472 PUA domain 276 347 8.6E-18 T 06-07-2017 IPR002478 PUA domain GO:0003723 SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 SUPERFAMILY SSF53633 5 255 1.01E-61 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 Gene3D G3DSA:3.40.1160.10 5 255 4.6E-55 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 Hamap MF_00456 Glutamate 5-kinase [proB]. 5 257 35.598 T 06-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMD11_RS22465 278c3d7f080fdb5a2d3ff81a6086ee63 369 ProSitePatterns PS00902 Glutamate 5-kinase signature. 209 226 - T 06-07-2017 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMD11_RS34065 f8b6db68f7d99f1d3b76ba87f89af480 437 SUPERFAMILY SSF51735 25 180 2.63E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS34065 f8b6db68f7d99f1d3b76ba87f89af480 437 SUPERFAMILY SSF69055 330 423 4.71E-27 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMD11_RS34065 f8b6db68f7d99f1d3b76ba87f89af480 437 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 176 263 2.6E-34 T 06-07-2017 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMD11_RS34065 f8b6db68f7d99f1d3b76ba87f89af480 437 PIRSF PIRSF006205 25 427 4.8E-122 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMD11_RS34065 f8b6db68f7d99f1d3b76ba87f89af480 437 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 28 421 40.274 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMD11_RS34065 f8b6db68f7d99f1d3b76ba87f89af480 437 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 28 164 7.1E-29 T 06-07-2017 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMD11_RS34065 f8b6db68f7d99f1d3b76ba87f89af480 437 Gene3D G3DSA:1.10.1740.10 340 422 9.2E-30 T 06-07-2017 SMD11_RS34065 f8b6db68f7d99f1d3b76ba87f89af480 437 Gene3D G3DSA:3.40.50.720 24 180 4.6E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS34065 f8b6db68f7d99f1d3b76ba87f89af480 437 Pfam PF13288 DXP reductoisomerase C-terminal domain 299 416 5.4E-36 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMD11_RS34065 f8b6db68f7d99f1d3b76ba87f89af480 437 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 26 423 5.2E-106 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMD11_RS34065 f8b6db68f7d99f1d3b76ba87f89af480 437 SUPERFAMILY SSF55347 158 300 3.04E-48 T 06-07-2017 SMD11_RS11850 449cee964a445b89a00fb907020c4387 194 Pfam PF03352 Methyladenine glycosylase 22 192 1.4E-67 T 06-07-2017 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 SMD11_RS11850 449cee964a445b89a00fb907020c4387 194 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 14 192 1.7E-71 T 06-07-2017 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 SMD11_RS11850 449cee964a445b89a00fb907020c4387 194 Gene3D G3DSA:1.10.340.30 13 193 6.0E-72 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD11_RS11850 449cee964a445b89a00fb907020c4387 194 SUPERFAMILY SSF48150 13 193 5.49E-68 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 Pfam PF00550 Phosphopantetheine attachment site 1667 1733 5.2E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 Gene3D G3DSA:3.40.50.720 1377 1581 5.7E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 Gene3D G3DSA:3.30.70.250 681 743 2.6E-10 T 06-07-2017 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 Pfam PF08990 Erythronolide synthase docking 4 27 4.1E-10 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 SUPERFAMILY SSF51735 1195 1371 1.38E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 SUPERFAMILY SSF47336 1660 1746 1.18E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 Gene3D G3DSA:3.40.366.10 556 676 6.1E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 Gene3D G3DSA:3.40.366.10 744 859 6.1E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 Pfam PF08659 KR domain 1381 1556 4.5E-56 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 Gene3D G3DSA:1.10.1200.10 1663 1737 9.6E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 2.5E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1381 1558 3.0E-56 T 06-07-2017 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 2.8E-92 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 Gene3D G3DSA:3.40.47.10 30 296 4.6E-91 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 SUPERFAMILY SSF52151 737 839 4.45E-73 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 SUPERFAMILY SSF52151 562 676 4.45E-73 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 SMART SM00825 Beta-ketoacyl synthase 36 463 1.1E-227 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 Pfam PF14765 Polyketide synthase dehydratase 923 1190 1.8E-53 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 Pfam PF00698 Acyl transferase domain 565 873 5.6E-53 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 SUPERFAMILY SSF51735 1378 1635 8.82E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 SMART SM01294 1666 1733 2.1E-5 T 06-07-2017 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 SUPERFAMILY SSF53901 31 406 1.8E-104 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 SMART SM00826 923 1085 2.7E-76 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 Gene3D G3DSA:3.40.47.10 297 464 2.2E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 565 855 2.5E-120 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 SUPERFAMILY SSF55048 681 744 1.57E-12 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 516 1.8E-13 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08270 7d6a5b0b778049c994c68cb282648142 1836 SMART SM00823 Phosphopantetheine attachment site 1665 1737 7.3E-31 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS12345 ebde002007dab259f7c1a1fe430dcb04 232 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 102 210 1.2E-18 T 06-07-2017 IPR031571 Flp pilus assembly protein RcpC/CpaB domain SMD11_RS12345 ebde002007dab259f7c1a1fe430dcb04 232 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 1 217 4.1E-26 T 06-07-2017 IPR017592 Pilus assembly, Flp-type CpaB SMD11_RS06505 3fc41234c70ff10c4e80d19a845cb9a3 170 SUPERFAMILY SSF54637 2 148 8.4E-43 T 06-07-2017 IPR029069 HotDog domain SMD11_RS06505 3fc41234c70ff10c4e80d19a845cb9a3 170 Gene3D G3DSA:3.10.129.10 2 148 5.0E-40 T 06-07-2017 IPR029069 HotDog domain SMD11_RS06505 3fc41234c70ff10c4e80d19a845cb9a3 170 Pfam PF01575 MaoC like domain 12 125 3.6E-15 T 06-07-2017 IPR002539 MaoC-like domain SMD11_RS31385 c4ea70047f6a40ab6a6eb8342b046efa 486 Pfam PF06114 Domain of unknown function (DUF955) 190 312 5.7E-19 T 06-07-2017 IPR010359 HTH domain, IrrE-type SMD11_RS31385 c4ea70047f6a40ab6a6eb8342b046efa 486 SMART SM00530 14 69 1.2E-16 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS31385 c4ea70047f6a40ab6a6eb8342b046efa 486 SUPERFAMILY SSF47413 12 74 7.78E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS31385 c4ea70047f6a40ab6a6eb8342b046efa 486 Gene3D G3DSA:1.10.260.40 9 78 3.0E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS31385 c4ea70047f6a40ab6a6eb8342b046efa 486 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 313 469 7.2E-70 T 06-07-2017 IPR018653 Domain of unknown function DUF2083,transcriptional regulator SMD11_RS31385 c4ea70047f6a40ab6a6eb8342b046efa 486 PIRSF PIRSF019251 1 474 3.5E-186 T 06-07-2017 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 SMD11_RS31385 c4ea70047f6a40ab6a6eb8342b046efa 486 Pfam PF01381 Helix-turn-helix 15 68 2.7E-14 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS15395 c44e8f102cee9337cf9bbd45eb063537 399 Pfam PF13365 Trypsin-like peptidase domain 220 358 7.0E-22 T 06-07-2017 SMD11_RS15395 c44e8f102cee9337cf9bbd45eb063537 399 SUPERFAMILY SSF50494 197 380 3.56E-34 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS15395 c44e8f102cee9337cf9bbd45eb063537 399 Gene3D G3DSA:2.40.10.10 288 380 1.5E-11 T 06-07-2017 SMD11_RS15395 c44e8f102cee9337cf9bbd45eb063537 399 Pfam PF02674 Colicin V production protein 4 145 2.6E-19 T 06-07-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 SMD11_RS15395 c44e8f102cee9337cf9bbd45eb063537 399 PRINTS PR00834 HtrA/DegQ protease family signature 329 346 3.7E-7 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS15395 c44e8f102cee9337cf9bbd45eb063537 399 PRINTS PR00834 HtrA/DegQ protease family signature 228 240 3.7E-7 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS15395 c44e8f102cee9337cf9bbd45eb063537 399 PRINTS PR00834 HtrA/DegQ protease family signature 250 270 3.7E-7 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS15395 c44e8f102cee9337cf9bbd45eb063537 399 Gene3D G3DSA:2.40.10.10 219 287 1.2E-14 T 06-07-2017 SMD11_RS24340 c765c6816e26b0c4cd8d079496a0790b 404 SMART SM00387 301 400 2.3E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS24340 c765c6816e26b0c4cd8d079496a0790b 404 SUPERFAMILY SSF55874 283 398 6.68E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS24340 c765c6816e26b0c4cd8d079496a0790b 404 Gene3D G3DSA:3.30.565.10 299 399 3.9E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS24340 c765c6816e26b0c4cd8d079496a0790b 404 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 309 398 1.3E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS24340 c765c6816e26b0c4cd8d079496a0790b 404 Pfam PF07730 Histidine kinase 181 221 3.2E-6 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS19950 81e6f397c935dbfaf60578c6ce630599 110 Gene3D G3DSA:1.10.10.10 18 106 7.9E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19950 81e6f397c935dbfaf60578c6ce630599 110 SMART SM00347 16 108 0.0096 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS19950 81e6f397c935dbfaf60578c6ce630599 110 SUPERFAMILY SSF46785 24 106 1.19E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19950 81e6f397c935dbfaf60578c6ce630599 110 Pfam PF13601 Winged helix DNA-binding domain 26 104 1.5E-23 T 06-07-2017 IPR027395 Winged helix DNA-binding domain SMD11_RS28930 a7dc5f06511c1ac9c42943e66906cd73 312 Pfam PF03466 LysR substrate binding domain 94 293 1.7E-23 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS28930 a7dc5f06511c1ac9c42943e66906cd73 312 SUPERFAMILY SSF46785 5 89 9.62E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28930 a7dc5f06511c1ac9c42943e66906cd73 312 Gene3D G3DSA:3.40.190.10 92 177 2.9E-17 T 06-07-2017 SMD11_RS28930 a7dc5f06511c1ac9c42943e66906cd73 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.5E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS28930 a7dc5f06511c1ac9c42943e66906cd73 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.5E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS28930 a7dc5f06511c1ac9c42943e66906cd73 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.5E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS28930 a7dc5f06511c1ac9c42943e66906cd73 312 Gene3D G3DSA:1.10.10.10 5 89 3.9E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28930 a7dc5f06511c1ac9c42943e66906cd73 312 SUPERFAMILY SSF53850 94 299 3.44E-21 T 06-07-2017 SMD11_RS28930 a7dc5f06511c1ac9c42943e66906cd73 312 Gene3D G3DSA:3.40.190.10 178 267 6.7E-10 T 06-07-2017 SMD11_RS28930 a7dc5f06511c1ac9c42943e66906cd73 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 5.3E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS32120 9bd0be13c72b09d684dcfbd26a9e1fa7 282 Gene3D G3DSA:1.10.10.10 217 275 6.3E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32120 9bd0be13c72b09d684dcfbd26a9e1fa7 282 SMART SM00421 213 270 1.6E-25 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS32120 9bd0be13c72b09d684dcfbd26a9e1fa7 282 SMART SM00448 66 179 2.8E-34 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS32120 9bd0be13c72b09d684dcfbd26a9e1fa7 282 Gene3D G3DSA:3.40.50.2300 67 216 1.6E-39 T 06-07-2017 SMD11_RS32120 9bd0be13c72b09d684dcfbd26a9e1fa7 282 Pfam PF00072 Response regulator receiver domain 68 179 3.1E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS32120 9bd0be13c72b09d684dcfbd26a9e1fa7 282 Pfam PF00196 Bacterial regulatory proteins, luxR family 215 270 1.3E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS32120 9bd0be13c72b09d684dcfbd26a9e1fa7 282 SUPERFAMILY SSF46894 206 275 4.42E-22 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS32120 9bd0be13c72b09d684dcfbd26a9e1fa7 282 ProSitePatterns PS00622 LuxR-type HTH domain signature. 230 257 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS32120 9bd0be13c72b09d684dcfbd26a9e1fa7 282 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 246 258 2.6E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS32120 9bd0be13c72b09d684dcfbd26a9e1fa7 282 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 230 246 2.6E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS32120 9bd0be13c72b09d684dcfbd26a9e1fa7 282 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 216 230 2.6E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS32120 9bd0be13c72b09d684dcfbd26a9e1fa7 282 SUPERFAMILY SSF52172 67 193 3.84E-34 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS03850 3863fe25fe9af8502f32d3066f92f84d 392 Gene3D G3DSA:1.20.140.10 223 388 1.2E-29 T 06-07-2017 SMD11_RS03850 3863fe25fe9af8502f32d3066f92f84d 392 Gene3D G3DSA:1.10.540.10 1 120 2.8E-26 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS03850 3863fe25fe9af8502f32d3066f92f84d 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 383 1.9E-21 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS03850 3863fe25fe9af8502f32d3066f92f84d 392 SUPERFAMILY SSF47203 232 385 2.09E-19 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS03850 3863fe25fe9af8502f32d3066f92f84d 392 Gene3D G3DSA:2.40.110.10 123 222 1.3E-24 T 06-07-2017 SMD11_RS03850 3863fe25fe9af8502f32d3066f92f84d 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 220 3.6E-16 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS03850 3863fe25fe9af8502f32d3066f92f84d 392 SUPERFAMILY SSF56645 2 242 2.75E-60 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS03850 3863fe25fe9af8502f32d3066f92f84d 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 7.2E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS18190 8363d54c641e15acaaec1453f5727144 269 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SMD11_RS18190 8363d54c641e15acaaec1453f5727144 269 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 264 27.647 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SMD11_RS18190 8363d54c641e15acaaec1453f5727144 269 ProSitePatterns PS00616 Histidine acid phosphatases phosphohistidine signature. 235 249 - T 06-07-2017 IPR033379 Histidine acid phosphatase active site SMD11_RS18190 8363d54c641e15acaaec1453f5727144 269 SUPERFAMILY SSF48179 159 265 3.4E-35 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS18190 8363d54c641e15acaaec1453f5727144 269 Gene3D G3DSA:1.10.3730.10 159 264 9.1E-41 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 SMD11_RS18190 8363d54c641e15acaaec1453f5727144 269 Gene3D G3DSA:3.40.50.720 3 157 8.2E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18190 8363d54c641e15acaaec1453f5727144 269 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 264 3.4E-81 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SMD11_RS18190 8363d54c641e15acaaec1453f5727144 269 PIRSF PIRSF000193 2 267 3.2E-80 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SMD11_RS18190 8363d54c641e15acaaec1453f5727144 269 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 97 4.4E-24 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMD11_RS18190 8363d54c641e15acaaec1453f5727144 269 SUPERFAMILY SSF51735 4 158 4.48E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18190 8363d54c641e15acaaec1453f5727144 269 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 160 264 6.2E-38 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 SMD11_RS19385 10a1a18d6fa5220b2de018f2330e333d 139 SUPERFAMILY SSF50249 8 129 5.65E-36 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS19385 10a1a18d6fa5220b2de018f2330e333d 139 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 59 124 4.9E-24 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal SMD11_RS19385 10a1a18d6fa5220b2de018f2330e333d 139 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 20 57 8.3E-11 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal SMD11_RS26615 50107c085d1fbaa34877105ca2458934 386 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 60 304 4.3E-108 T 06-07-2017 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 SMD11_RS26615 50107c085d1fbaa34877105ca2458934 386 Gene3D G3DSA:3.40.50.300 61 288 7.5E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26615 50107c085d1fbaa34877105ca2458934 386 ProSitePatterns PS00211 ABC transporters family signature. 187 201 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS26615 50107c085d1fbaa34877105ca2458934 386 Gene3D G3DSA:3.10.580.10 298 366 4.3E-7 T 06-07-2017 SMD11_RS26615 50107c085d1fbaa34877105ca2458934 386 Pfam PF00005 ABC transporter 68 214 3.2E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS26615 50107c085d1fbaa34877105ca2458934 386 SMART SM00382 75 272 2.1E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS26615 50107c085d1fbaa34877105ca2458934 386 SUPERFAMILY SSF52540 65 292 5.19E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26615 50107c085d1fbaa34877105ca2458934 386 SUPERFAMILY SSF54631 306 368 3.01E-7 T 06-07-2017 SMD11_RS32915 8564bdfaf32cbb4af750d9d09af86b3e 467 Gene3D G3DSA:3.90.1150.10 275 402 4.2E-13 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS32915 8564bdfaf32cbb4af750d9d09af86b3e 467 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 35 368 5.7E-97 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMD11_RS32915 8564bdfaf32cbb4af750d9d09af86b3e 467 Gene3D G3DSA:3.40.640.10 29 273 9.1E-78 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS32915 8564bdfaf32cbb4af750d9d09af86b3e 467 SUPERFAMILY SSF53383 31 396 4.26E-90 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS19780 f6fcfb11ff1d2df12ec1dce6aaafc97e 303 SMART SM00382 34 210 1.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS19780 f6fcfb11ff1d2df12ec1dce6aaafc97e 303 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS19780 f6fcfb11ff1d2df12ec1dce6aaafc97e 303 Gene3D G3DSA:3.40.50.300 7 225 5.3E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19780 f6fcfb11ff1d2df12ec1dce6aaafc97e 303 SUPERFAMILY SSF52540 9 224 8.58E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19780 f6fcfb11ff1d2df12ec1dce6aaafc97e 303 Pfam PF00005 ABC transporter 25 161 2.9E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS01900 50cdce21fa40540dc44c09d710fc0cde 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 377 3.6E-17 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS01900 50cdce21fa40540dc44c09d710fc0cde 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 132 223 9.6E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS01900 50cdce21fa40540dc44c09d710fc0cde 386 SUPERFAMILY SSF47203 241 379 5.96E-17 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS01900 50cdce21fa40540dc44c09d710fc0cde 386 Gene3D G3DSA:1.20.140.10 225 379 3.0E-20 T 06-07-2017 SMD11_RS01900 50cdce21fa40540dc44c09d710fc0cde 386 SUPERFAMILY SSF56645 1 232 9.29E-36 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS01900 50cdce21fa40540dc44c09d710fc0cde 386 Gene3D G3DSA:1.10.540.10 1 123 1.6E-5 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS01900 50cdce21fa40540dc44c09d710fc0cde 386 Gene3D G3DSA:2.40.110.10 132 224 5.2E-25 T 06-07-2017 SMD11_RS20130 88b70fceb2af6496d1b68fb05e390e47 258 SUPERFAMILY SSF46894 172 241 5.1E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS20130 88b70fceb2af6496d1b68fb05e390e47 258 SMART SM00448 4 143 2.5E-15 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS20130 88b70fceb2af6496d1b68fb05e390e47 258 SMART SM00421 179 236 6.4E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20130 88b70fceb2af6496d1b68fb05e390e47 258 Gene3D G3DSA:3.40.50.2300 3 180 6.3E-37 T 06-07-2017 SMD11_RS20130 88b70fceb2af6496d1b68fb05e390e47 258 Pfam PF00196 Bacterial regulatory proteins, luxR family 181 236 6.8E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20130 88b70fceb2af6496d1b68fb05e390e47 258 SUPERFAMILY SSF52172 3 150 1.66E-14 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS20130 88b70fceb2af6496d1b68fb05e390e47 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 212 8.8E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20130 88b70fceb2af6496d1b68fb05e390e47 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 196 8.8E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20130 88b70fceb2af6496d1b68fb05e390e47 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 212 224 8.8E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20130 88b70fceb2af6496d1b68fb05e390e47 258 Pfam PF00072 Response regulator receiver domain 6 65 4.0E-5 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS20130 88b70fceb2af6496d1b68fb05e390e47 258 Gene3D G3DSA:1.10.10.10 181 241 3.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19530 65c3b1e578a05a0eb0c9ddcc98e6ac43 864 Hamap MF_01611 FO synthase subunit 1 [cofG]. 71 402 50.12 T 06-07-2017 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD11_RS19530 65c3b1e578a05a0eb0c9ddcc98e6ac43 864 SMART SM00729 75 312 5.1E-6 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD11_RS19530 65c3b1e578a05a0eb0c9ddcc98e6ac43 864 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 530 838 1.3E-107 T 06-07-2017 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD11_RS19530 65c3b1e578a05a0eb0c9ddcc98e6ac43 864 SUPERFAMILY SSF102114 493 805 7.59E-48 T 06-07-2017 SMD11_RS19530 65c3b1e578a05a0eb0c9ddcc98e6ac43 864 Hamap MF_01612 FO synthase subunit 2 [cofH]. 481 841 48.28 T 06-07-2017 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD11_RS19530 65c3b1e578a05a0eb0c9ddcc98e6ac43 864 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 496 840 3.1E-161 T 06-07-2017 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD11_RS19530 65c3b1e578a05a0eb0c9ddcc98e6ac43 864 SUPERFAMILY SSF102114 31 377 4.45E-37 T 06-07-2017 SMD11_RS19530 65c3b1e578a05a0eb0c9ddcc98e6ac43 864 Pfam PF04055 Radical SAM superfamily 538 699 2.3E-14 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS19530 65c3b1e578a05a0eb0c9ddcc98e6ac43 864 Pfam PF04055 Radical SAM superfamily 79 261 1.3E-14 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS19530 65c3b1e578a05a0eb0c9ddcc98e6ac43 864 Gene3D G3DSA:3.20.20.70 494 830 1.2E-74 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS19530 65c3b1e578a05a0eb0c9ddcc98e6ac43 864 Gene3D G3DSA:3.20.20.70 31 363 2.4E-67 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS19530 65c3b1e578a05a0eb0c9ddcc98e6ac43 864 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 72 400 1.1E-142 T 06-07-2017 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD11_RS03395 cd833dd77497e1479505bbd5ff1eff1e 311 Gene3D G3DSA:3.30.2010.10 111 196 9.7E-10 T 06-07-2017 SMD11_RS03395 cd833dd77497e1479505bbd5ff1eff1e 311 Pfam PF01435 Peptidase family M48 118 216 1.2E-9 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMD11_RS33900 c25c31f5e27c5255452b684ae573c9e7 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 6.7E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33900 c25c31f5e27c5255452b684ae573c9e7 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 6.7E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33900 c25c31f5e27c5255452b684ae573c9e7 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 6.7E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33900 c25c31f5e27c5255452b684ae573c9e7 316 Pfam PF00106 short chain dehydrogenase 22 162 5.8E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33900 c25c31f5e27c5255452b684ae573c9e7 316 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 21 243 0.0079 T 06-07-2017 SMD11_RS33900 c25c31f5e27c5255452b684ae573c9e7 316 SUPERFAMILY SSF51735 19 241 5.56E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33900 c25c31f5e27c5255452b684ae573c9e7 316 Gene3D G3DSA:3.40.50.720 19 228 3.6E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10450 c1f36d323f2287bcb8fa29b1f60bf164 309 Gene3D G3DSA:1.10.3720.10 80 308 5.6E-53 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS10450 c1f36d323f2287bcb8fa29b1f60bf164 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 301 2.2E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS10450 c1f36d323f2287bcb8fa29b1f60bf164 309 SUPERFAMILY SSF161098 74 299 2.62E-53 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS10450 c1f36d323f2287bcb8fa29b1f60bf164 309 SUPERFAMILY SSF160964 27 62 3.01E-6 T 06-07-2017 SMD11_RS10450 c1f36d323f2287bcb8fa29b1f60bf164 309 Gene3D G3DSA:1.20.58.370 26 60 1.3E-5 T 06-07-2017 SMD11_RS27865 7e18d20f9766728ad22a3e2779b14546 253 SUPERFAMILY SSF53448 15 227 1.78E-43 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS27865 7e18d20f9766728ad22a3e2779b14546 253 Pfam PF00535 Glycosyl transferase family 2 17 179 3.3E-29 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD11_RS27865 7e18d20f9766728ad22a3e2779b14546 253 Gene3D G3DSA:3.90.550.10 17 224 6.6E-26 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS24315 09e000332576cacf164b8e4efc45b5f4 313 ProSitePatterns PS01125 ROK family signature. 130 157 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS24315 09e000332576cacf164b8e4efc45b5f4 313 SUPERFAMILY SSF53067 2 312 8.3E-71 T 06-07-2017 SMD11_RS24315 09e000332576cacf164b8e4efc45b5f4 313 Pfam PF00480 ROK family 4 312 5.6E-102 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS24315 09e000332576cacf164b8e4efc45b5f4 313 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 5 311 2.4E-133 T 06-07-2017 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 SMD11_RS24315 09e000332576cacf164b8e4efc45b5f4 313 Gene3D G3DSA:3.30.420.40 135 286 1.1E-51 T 06-07-2017 SMD11_RS24315 09e000332576cacf164b8e4efc45b5f4 313 Gene3D G3DSA:3.30.420.40 1 134 2.6E-48 T 06-07-2017 SMD11_RS22190 c275e7e1cc19bc17df40f521a9222d78 887 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 584 594 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site SMD11_RS22190 c275e7e1cc19bc17df40f521a9222d78 887 Gene3D G3DSA:3.40.50.200 197 245 1.6E-70 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS22190 c275e7e1cc19bc17df40f521a9222d78 887 Gene3D G3DSA:3.40.50.200 390 645 1.6E-70 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS22190 c275e7e1cc19bc17df40f521a9222d78 887 PRINTS PR00723 Subtilisin serine protease family (S8) signature 386 399 3.1E-16 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS22190 c275e7e1cc19bc17df40f521a9222d78 887 PRINTS PR00723 Subtilisin serine protease family (S8) signature 583 599 3.1E-16 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS22190 c275e7e1cc19bc17df40f521a9222d78 887 PRINTS PR00723 Subtilisin serine protease family (S8) signature 201 220 3.1E-16 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS22190 c275e7e1cc19bc17df40f521a9222d78 887 Pfam PF00082 Subtilase family 201 637 4.1E-57 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS22190 c275e7e1cc19bc17df40f521a9222d78 887 SUPERFAMILY SSF52743 193 221 4.58E-55 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS22190 c275e7e1cc19bc17df40f521a9222d78 887 SUPERFAMILY SSF52743 389 646 4.58E-55 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS22190 c275e7e1cc19bc17df40f521a9222d78 887 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 206 217 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site SMD11_RS09570 28b9d5635b7e711bf6e38ab8d7b689ef 356 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 94 292 7.0E-39 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09570 28b9d5635b7e711bf6e38ab8d7b689ef 356 Pfam PF10502 Signal peptidase, peptidase S26 191 286 8.3E-9 T 06-07-2017 IPR019533 Peptidase S26 SMD11_RS09570 28b9d5635b7e711bf6e38ab8d7b689ef 356 ProSitePatterns PS00761 Signal peptidases I signature 3. 251 264 - T 06-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 SMD11_RS09570 28b9d5635b7e711bf6e38ab8d7b689ef 356 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 246 265 1.3E-18 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09570 28b9d5635b7e711bf6e38ab8d7b689ef 356 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 195 207 1.3E-18 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09570 28b9d5635b7e711bf6e38ab8d7b689ef 356 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 107 123 1.3E-18 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09570 28b9d5635b7e711bf6e38ab8d7b689ef 356 Pfam PF00717 Peptidase S24-like 114 156 2.6E-11 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B SMD11_RS09570 28b9d5635b7e711bf6e38ab8d7b689ef 356 SUPERFAMILY SSF51306 106 154 1.62E-46 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C SMD11_RS09570 28b9d5635b7e711bf6e38ab8d7b689ef 356 SUPERFAMILY SSF51306 190 297 1.62E-46 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C SMD11_RS09570 28b9d5635b7e711bf6e38ab8d7b689ef 356 Gene3D G3DSA:2.10.109.10 189 205 2.5E-39 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain SMD11_RS09570 28b9d5635b7e711bf6e38ab8d7b689ef 356 Gene3D G3DSA:2.10.109.10 246 297 2.5E-39 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain SMD11_RS09570 28b9d5635b7e711bf6e38ab8d7b689ef 356 Gene3D G3DSA:2.10.109.10 103 153 2.5E-39 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain SMD11_RS11185 57ac41c1dde1fc2a93ab0c67a9b21cd3 459 SMART SM00098 55 459 2.2E-160 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SMD11_RS11185 57ac41c1dde1fc2a93ab0c67a9b21cd3 459 PRINTS PR00113 Alkaline phosphatase signature 307 336 7.6E-35 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SMD11_RS11185 57ac41c1dde1fc2a93ab0c67a9b21cd3 459 PRINTS PR00113 Alkaline phosphatase signature 147 167 7.6E-35 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SMD11_RS11185 57ac41c1dde1fc2a93ab0c67a9b21cd3 459 PRINTS PR00113 Alkaline phosphatase signature 54 74 7.6E-35 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SMD11_RS11185 57ac41c1dde1fc2a93ab0c67a9b21cd3 459 PRINTS PR00113 Alkaline phosphatase signature 209 219 7.6E-35 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SMD11_RS11185 57ac41c1dde1fc2a93ab0c67a9b21cd3 459 PRINTS PR00113 Alkaline phosphatase signature 109 124 7.6E-35 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SMD11_RS11185 57ac41c1dde1fc2a93ab0c67a9b21cd3 459 Pfam PF00245 Alkaline phosphatase 54 412 7.3E-106 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SMD11_RS11185 57ac41c1dde1fc2a93ab0c67a9b21cd3 459 ProSitePatterns PS00123 Alkaline phosphatase active site. 109 117 - T 06-07-2017 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SMD11_RS11185 57ac41c1dde1fc2a93ab0c67a9b21cd3 459 Gene3D G3DSA:3.40.720.10 43 458 6.9E-120 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMD11_RS11185 57ac41c1dde1fc2a93ab0c67a9b21cd3 459 SUPERFAMILY SSF53649 45 457 4.25E-118 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMD11_RS22030 ae980ec5abb3f37c3432d98e5589e814 154 SUPERFAMILY SSF54637 4 132 7.85E-34 T 06-07-2017 IPR029069 HotDog domain SMD11_RS22030 ae980ec5abb3f37c3432d98e5589e814 154 Pfam PF03061 Thioesterase superfamily 18 100 4.0E-18 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 SMD11_RS22030 ae980ec5abb3f37c3432d98e5589e814 154 Gene3D G3DSA:3.10.129.10 3 134 4.0E-48 T 06-07-2017 IPR029069 HotDog domain SMD11_RS12195 6117b6d79af3586f897bb84e71ad00f2 632 Gene3D G3DSA:3.30.450.40 67 103 4.3E-23 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS12195 6117b6d79af3586f897bb84e71ad00f2 632 Gene3D G3DSA:3.30.450.40 142 261 4.3E-23 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS12195 6117b6d79af3586f897bb84e71ad00f2 632 SUPERFAMILY SSF55781 207 271 4.71E-7 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS12195 6117b6d79af3586f897bb84e71ad00f2 632 SUPERFAMILY SSF55874 533 623 2.26E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS12195 6117b6d79af3586f897bb84e71ad00f2 632 Pfam PF13581 Histidine kinase-like ATPase domain 516 609 2.8E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS12195 6117b6d79af3586f897bb84e71ad00f2 632 SUPERFAMILY SSF81606 299 502 8.37E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS12195 6117b6d79af3586f897bb84e71ad00f2 632 SMART SM00331 285 501 7.2E-37 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS12195 6117b6d79af3586f897bb84e71ad00f2 632 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 311 501 4.3E-52 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS31745 8819ecd179eb970c166b132cd85067a3 594 SUPERFAMILY SSF56235 3 224 2.23E-40 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS31745 8819ecd179eb970c166b132cd85067a3 594 Pfam PF13537 Glutamine amidotransferase domain 54 169 2.6E-22 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain SMD11_RS31745 8819ecd179eb970c166b132cd85067a3 594 SUPERFAMILY SSF52402 440 548 1.81E-41 T 06-07-2017 SMD11_RS31745 8819ecd179eb970c166b132cd85067a3 594 SUPERFAMILY SSF52402 221 376 1.81E-41 T 06-07-2017 SMD11_RS31745 8819ecd179eb970c166b132cd85067a3 594 Gene3D G3DSA:3.40.50.620 447 552 1.3E-40 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS31745 8819ecd179eb970c166b132cd85067a3 594 Gene3D G3DSA:3.40.50.620 225 382 1.3E-40 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS31745 8819ecd179eb970c166b132cd85067a3 594 PIRSF PIRSF001589 4 588 1.6E-85 T 06-07-2017 SMD11_RS31745 8819ecd179eb970c166b132cd85067a3 594 Pfam PF00733 Asparagine synthase 259 581 1.5E-43 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMD11_RS31745 8819ecd179eb970c166b132cd85067a3 594 Gene3D G3DSA:3.60.20.10 4 224 3.9E-42 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS22250 0fb44b61fa16a15c01b8a71ea99cfcb8 483 Pfam PF00324 Amino acid permease 37 445 4.0E-115 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMD11_RS22250 0fb44b61fa16a15c01b8a71ea99cfcb8 483 ProSitePatterns PS00218 Amino acid permeases signature. 62 92 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD11_RS22250 0fb44b61fa16a15c01b8a71ea99cfcb8 483 PIRSF PIRSF006060 13 478 2.6E-73 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS13705 1c989ea345a49564848c5facb79419c0 326 Gene3D G3DSA:2.130.10.10 31 256 5.1E-12 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS13705 1c989ea345a49564848c5facb79419c0 326 SUPERFAMILY SSF50969 29 249 8.63E-15 T 06-07-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like SMD11_RS09445 3f3c107161fe2e394b67a206d8ee6c40 483 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 283 294 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS09445 3f3c107161fe2e394b67a206d8ee6c40 483 Gene3D G3DSA:3.40.309.10 270 458 8.5E-64 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS09445 3f3c107161fe2e394b67a206d8ee6c40 483 SUPERFAMILY SSF53720 5 481 2.49E-158 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS09445 3f3c107161fe2e394b67a206d8ee6c40 483 Pfam PF00171 Aldehyde dehydrogenase family 19 478 5.7E-160 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS09445 3f3c107161fe2e394b67a206d8ee6c40 483 Gene3D G3DSA:3.40.605.10 7 269 2.9E-88 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS09445 3f3c107161fe2e394b67a206d8ee6c40 483 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS32485 864a76e64794ca1b03d12d7ca8de92ee 361 SUPERFAMILY SSF144284 128 212 5.23E-6 T 06-07-2017 SMD11_RS32485 864a76e64794ca1b03d12d7ca8de92ee 361 Pfam PF00072 Response regulator receiver domain 234 347 4.1E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS32485 864a76e64794ca1b03d12d7ca8de92ee 361 SUPERFAMILY SSF52172 230 352 1.71E-36 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS32485 864a76e64794ca1b03d12d7ca8de92ee 361 Gene3D G3DSA:3.40.50.2300 228 350 5.0E-37 T 06-07-2017 SMD11_RS32485 864a76e64794ca1b03d12d7ca8de92ee 361 SMART SM00448 232 347 1.7E-33 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS28230 fe85dc01bd72b5bc3e054dd683e67b95 198 SUPERFAMILY SSF46785 49 142 8.13E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28230 fe85dc01bd72b5bc3e054dd683e67b95 198 Pfam PF03551 Transcriptional regulator PadR-like family 63 130 1.1E-20 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal SMD11_RS28230 fe85dc01bd72b5bc3e054dd683e67b95 198 Gene3D G3DSA:1.10.10.10 53 136 7.0E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23110 c4d242b8952f54286452454ed01d0ebf 339 SUPERFAMILY SSF51735 126 302 7.67E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS23110 c4d242b8952f54286452454ed01d0ebf 339 SMART SM00829 22 335 5.7E-9 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS23110 c4d242b8952f54286452454ed01d0ebf 339 Pfam PF16884 N-terminal domain of oxidoreductase 9 115 2.8E-42 T 06-07-2017 SMD11_RS23110 c4d242b8952f54286452454ed01d0ebf 339 Gene3D G3DSA:3.90.180.10 4 143 1.3E-54 T 06-07-2017 IPR011032 GroES-like SMD11_RS23110 c4d242b8952f54286452454ed01d0ebf 339 SUPERFAMILY SSF50129 6 144 9.43E-44 T 06-07-2017 IPR011032 GroES-like SMD11_RS23110 c4d242b8952f54286452454ed01d0ebf 339 Pfam PF00107 Zinc-binding dehydrogenase 161 289 1.8E-24 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS23110 c4d242b8952f54286452454ed01d0ebf 339 Gene3D G3DSA:3.40.50.720 144 305 7.3E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19300 b2b6010af993e7840d7ad304b8992b44 955 Gene3D G3DSA:3.30.200.20 103 157 2.8E-7 T 06-07-2017 SMD11_RS19300 b2b6010af993e7840d7ad304b8992b44 955 SUPERFAMILY SSF56112 527 630 5.03E-20 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS19300 b2b6010af993e7840d7ad304b8992b44 955 SUPERFAMILY SSF56112 99 192 5.03E-20 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS19300 b2b6010af993e7840d7ad304b8992b44 955 SMART SM00220 23 630 5.0E-9 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS19300 b2b6010af993e7840d7ad304b8992b44 955 Pfam PF00069 Protein kinase domain 106 184 7.0E-7 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS19300 b2b6010af993e7840d7ad304b8992b44 955 Gene3D G3DSA:1.10.510.10 525 630 2.4E-16 T 06-07-2017 SMD11_RS19300 b2b6010af993e7840d7ad304b8992b44 955 Gene3D G3DSA:1.10.510.10 158 197 2.4E-16 T 06-07-2017 SMD11_RS23360 863cef2f25a4c496a85132ff116ae639 687 Gene3D G3DSA:3.60.21.10 184 267 1.8E-4 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS23360 863cef2f25a4c496a85132ff116ae639 687 Gene3D G3DSA:3.60.21.10 344 413 1.8E-4 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS23360 863cef2f25a4c496a85132ff116ae639 687 SUPERFAMILY SSF56300 170 263 3.79E-9 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS23360 863cef2f25a4c496a85132ff116ae639 687 SUPERFAMILY SSF56300 345 436 3.79E-9 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS23360 863cef2f25a4c496a85132ff116ae639 687 SUPERFAMILY SSF56300 469 516 3.79E-9 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS23360 863cef2f25a4c496a85132ff116ae639 687 Pfam PF09423 PhoD-like phosphatase 185 279 1.6E-9 T 06-07-2017 IPR018946 Alkaline phosphatase D-related SMD11_RS09695 e87af24293f4b70960f0f117fca687ef 267 SUPERFAMILY SSF69065 23 183 4.19E-49 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SMD11_RS09695 e87af24293f4b70960f0f117fca687ef 267 Gene3D G3DSA:1.10.1520.10 30 171 9.6E-46 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SMD11_RS09695 e87af24293f4b70960f0f117fca687ef 267 ProSitePatterns PS00517 Ribonuclease III family signature. 63 71 - T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SMD11_RS09695 e87af24293f4b70960f0f117fca687ef 267 Gene3D G3DSA:3.30.160.20 179 247 9.6E-26 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain SMD11_RS09695 e87af24293f4b70960f0f117fca687ef 267 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 33 245 5.7E-73 T 06-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 SMD11_RS09695 e87af24293f4b70960f0f117fca687ef 267 Pfam PF14622 Ribonuclease-III-like 41 165 1.0E-37 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SMD11_RS09695 e87af24293f4b70960f0f117fca687ef 267 SMART SM00535 41 174 6.5E-61 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SMD11_RS09695 e87af24293f4b70960f0f117fca687ef 267 Pfam PF00035 Double-stranded RNA binding motif 181 244 5.8E-18 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain SMD11_RS09695 e87af24293f4b70960f0f117fca687ef 267 Hamap MF_00104 Ribonuclease 3 [rnc]. 30 243 30.546 T 06-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 SMD11_RS09695 e87af24293f4b70960f0f117fca687ef 267 SUPERFAMILY SSF54768 135 246 2.99E-26 T 06-07-2017 SMD11_RS09695 e87af24293f4b70960f0f117fca687ef 267 SMART SM00358 181 247 2.5E-23 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain SMD11_RS18895 35ce56c15f5beedbe9d514d5a7c11eab 107 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 15 104 23.007 T 06-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 SMD11_RS18895 35ce56c15f5beedbe9d514d5a7c11eab 107 ProSitePatterns PS00050 Ribosomal protein L23 signature. 87 102 - T 06-07-2017 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18895 35ce56c15f5beedbe9d514d5a7c11eab 107 SUPERFAMILY SSF54189 13 104 1.37E-33 T 06-07-2017 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18895 35ce56c15f5beedbe9d514d5a7c11eab 107 Gene3D G3DSA:3.30.70.330 13 103 2.8E-37 T 06-07-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 SMD11_RS18895 35ce56c15f5beedbe9d514d5a7c11eab 107 Pfam PF00276 Ribosomal protein L23 16 101 7.0E-33 T 06-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 917 1033 1.6E-16 T 06-07-2017 IPR010033 HAD-superfamily phosphatase, subfamily IIIC SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 97 5.8E-7 T 06-07-2017 SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 SMART SM00823 Phosphopantetheine attachment site 203 274 3.5E-9 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 SUPERFAMILY SSF52777 481 704 5.78E-28 T 06-07-2017 SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 Gene3D G3DSA:3.40.50.1000 915 1044 3.3E-11 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 Gene3D G3DSA:1.10.1200.10 197 296 9.2E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 SUPERFAMILY SSF47336 197 275 7.33E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 Pfam PF08659 KR domain 1 95 4.7E-35 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 Pfam PF00668 Condensation domain 325 573 2.1E-15 T 06-07-2017 IPR001242 Condensation domain SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 SUPERFAMILY SSF55729 1140 1231 2.27E-5 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 SUPERFAMILY SSF56784 916 1034 4.52E-9 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 SUPERFAMILY SSF52777 320 459 1.56E-18 T 06-07-2017 SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 Gene3D G3DSA:3.40.630.30 1100 1232 7.7E-6 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 SUPERFAMILY SSF51735 1 172 1.58E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 TIGRFAM TIGR01686 FkbH: FkbH domain 914 1234 1.2E-105 T 06-07-2017 IPR010037 FkbH domain SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 Gene3D G3DSA:3.40.50.720 1 129 4.8E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS34325 7fb9671da70c5e146c86905f47a0cf4e 1265 Pfam PF00550 Phosphopantetheine attachment site 204 270 2.3E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS04370 91f9cfba452adac1c62805f012d83dc8 521 Pfam PF11066 Protein of unknown function (DUF2867) 364 509 9.3E-42 T 06-07-2017 IPR021295 Protein of unknown function DUF2867 SMD11_RS04370 91f9cfba452adac1c62805f012d83dc8 521 SUPERFAMILY SSF55961 373 518 3.13E-7 T 06-07-2017 SMD11_RS04370 91f9cfba452adac1c62805f012d83dc8 521 Gene3D G3DSA:3.40.50.720 33 264 1.5E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04370 91f9cfba452adac1c62805f012d83dc8 521 SUPERFAMILY SSF51735 33 267 3.1E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04370 91f9cfba452adac1c62805f012d83dc8 521 Pfam PF13460 NAD(P)H-binding 39 147 6.7E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS22265 f881e6170ed7d7645b50eaff99c61366 409 Pfam PF13530 Sterol carrier protein domain 180 405 4.0E-53 T 06-07-2017 IPR025559 Enhanced intracellular survival protein domain SMD11_RS22265 f881e6170ed7d7645b50eaff99c61366 409 Gene3D G3DSA:3.40.630.30 1 127 1.9E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS22265 f881e6170ed7d7645b50eaff99c61366 409 SUPERFAMILY SSF55718 304 409 5.89E-26 T 06-07-2017 IPR003033 SCP2 sterol-binding domain SMD11_RS22265 f881e6170ed7d7645b50eaff99c61366 409 SUPERFAMILY SSF55729 4 303 2.69E-63 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS22265 f881e6170ed7d7645b50eaff99c61366 409 Pfam PF13527 Acetyltransferase (GNAT) domain 4 130 5.3E-35 T 06-07-2017 SMD11_RS22265 f881e6170ed7d7645b50eaff99c61366 409 Gene3D G3DSA:3.30.1050.10 290 397 6.1E-27 T 06-07-2017 IPR003033 SCP2 sterol-binding domain SMD11_RS22265 f881e6170ed7d7645b50eaff99c61366 409 Gene3D G3DSA:3.40.630.30 128 289 1.9E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 PRINTS PR00385 P450 superfamily signature 362 373 6.3E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 PRINTS PR00385 P450 superfamily signature 250 267 6.3E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 PRINTS PR00385 P450 superfamily signature 285 296 6.3E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 PRINTS PR00385 P450 superfamily signature 353 362 6.3E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 PRINTS PR00359 B-class P450 signature 99 110 1.8E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 PRINTS PR00359 B-class P450 signature 303 330 1.8E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 PRINTS PR00359 B-class P450 signature 285 296 1.8E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 PRINTS PR00359 B-class P450 signature 353 362 1.8E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 PRINTS PR00359 B-class P450 signature 148 164 1.8E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 PRINTS PR00359 B-class P450 signature 362 373 1.8E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 PRINTS PR00359 B-class P450 signature 203 225 1.8E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 Pfam PF00067 Cytochrome P450 284 383 8.5E-16 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 Pfam PF00067 Cytochrome P450 219 277 5.4E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 SUPERFAMILY SSF48264 21 413 4.71E-93 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 355 364 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS08335 f3e33de278cad82eee1a6a516f810fe5 414 Gene3D G3DSA:1.10.630.10 18 412 3.3E-121 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS13865 7fe548cfb741727ee480a281e57b8cc5 701 Pfam PF13245 Part of AAA domain 214 272 5.0E-12 T 06-07-2017 SMD11_RS13865 7fe548cfb741727ee480a281e57b8cc5 701 Gene3D G3DSA:3.40.50.300 541 694 7.5E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13865 7fe548cfb741727ee480a281e57b8cc5 701 SUPERFAMILY SSF52540 449 694 1.73E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13865 7fe548cfb741727ee480a281e57b8cc5 701 SUPERFAMILY SSF52540 193 272 1.73E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13865 7fe548cfb741727ee480a281e57b8cc5 701 Gene3D G3DSA:3.40.50.300 397 540 2.9E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13865 7fe548cfb741727ee480a281e57b8cc5 701 Gene3D G3DSA:3.40.50.300 200 262 2.9E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13865 7fe548cfb741727ee480a281e57b8cc5 701 Pfam PF13538 UvrD-like helicase C-terminal domain 647 691 4.3E-7 T 06-07-2017 IPR027785 UvrD-like helicase C-terminal domain SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 SUPERFAMILY SSF88659 185 275 5.05E-25 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 SUPERFAMILY SSF88659 121 200 1.09E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 44 273 3.7E-36 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 Gene3D G3DSA:1.10.10.10 120 165 1.4E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 48 273 8.8E-88 T 06-07-2017 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 PIRSF PIRSF000770 24 277 6.7E-74 T 06-07-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 Pfam PF04539 Sigma-70 region 3 128 208 3.3E-7 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 243 269 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 SUPERFAMILY SSF88946 21 120 1.41E-26 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 75 88 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 Pfam PF04545 Sigma-70, region 4 222 271 1.4E-18 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 Pfam PF04542 Sigma-70 region 2 48 120 1.5E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 Gene3D G3DSA:1.10.601.10 30 111 1.4E-17 T 06-07-2017 SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 Gene3D G3DSA:1.10.10.10 211 275 3.0E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 PRINTS PR00046 Major sigma-70 factor signature 258 269 5.7E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 PRINTS PR00046 Major sigma-70 factor signature 243 258 5.7E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 PRINTS PR00046 Major sigma-70 factor signature 75 88 5.7E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS09535 52c39f67217d8a6a8f69f14a59057853 278 PRINTS PR00046 Major sigma-70 factor signature 226 238 5.7E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS02650 207ca2700e39aacc0136fee638ec8c6a 226 SMART SM00895 88 212 1.2E-16 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS02650 207ca2700e39aacc0136fee638ec8c6a 226 SUPERFAMILY SSF48008 85 217 1.49E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS02650 207ca2700e39aacc0136fee638ec8c6a 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 78 6.3E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS02650 207ca2700e39aacc0136fee638ec8c6a 226 Gene3D G3DSA:1.10.10.10 11 79 5.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02650 207ca2700e39aacc0136fee638ec8c6a 226 Pfam PF07729 FCD domain 90 210 8.7E-25 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS02650 207ca2700e39aacc0136fee638ec8c6a 226 SMART SM00345 20 78 7.6E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS02650 207ca2700e39aacc0136fee638ec8c6a 226 Gene3D G3DSA:1.20.120.530 83 215 1.2E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS02650 207ca2700e39aacc0136fee638ec8c6a 226 SUPERFAMILY SSF46785 14 82 8.47E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12270 1cdad496d712608d5fdbfb95043cfd7e 193 Gene3D G3DSA:1.10.357.10 70 193 5.0E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS12270 1cdad496d712608d5fdbfb95043cfd7e 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 5.7E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS12270 1cdad496d712608d5fdbfb95043cfd7e 193 SUPERFAMILY SSF46689 2 82 9.98E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS12270 1cdad496d712608d5fdbfb95043cfd7e 193 Gene3D G3DSA:1.10.10.60 1 64 8.4E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS12270 1cdad496d712608d5fdbfb95043cfd7e 193 SUPERFAMILY SSF48498 79 193 1.72E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS01320 b58faaad8e29d7206ed92bad6dc2dec5 333 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 237 325 1.1E-26 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS01320 b58faaad8e29d7206ed92bad6dc2dec5 333 Gene3D G3DSA:3.40.47.10 1 157 8.7E-42 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS01320 b58faaad8e29d7206ed92bad6dc2dec5 333 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 104 184 2.6E-23 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS01320 b58faaad8e29d7206ed92bad6dc2dec5 333 Gene3D G3DSA:3.40.47.10 158 326 3.8E-40 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS01320 b58faaad8e29d7206ed92bad6dc2dec5 333 SUPERFAMILY SSF53901 6 326 8.72E-47 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS01165 7ecfc5d9437707f98281e86adfccff20 389 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 211 7.5E-59 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain SMD11_RS01165 7ecfc5d9437707f98281e86adfccff20 389 Gene3D G3DSA:3.30.1220.10 246 353 1.1E-16 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD11_RS01165 7ecfc5d9437707f98281e86adfccff20 389 SMART SM00833 257 353 5.7E-32 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD11_RS01165 7ecfc5d9437707f98281e86adfccff20 389 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 257 353 1.7E-24 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD11_RS01165 7ecfc5d9437707f98281e86adfccff20 389 SUPERFAMILY SSF52540 3 310 3.1E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01165 7ecfc5d9437707f98281e86adfccff20 389 Gene3D G3DSA:3.40.50.300 4 230 1.5E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14780 f4ee5f80c224f760481dd4ac9742204a 433 SUPERFAMILY SSF158472 159 211 9.29E-5 T 06-07-2017 SMD11_RS14780 f4ee5f80c224f760481dd4ac9742204a 433 Gene3D G3DSA:3.30.565.10 276 418 9.4E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14780 f4ee5f80c224f760481dd4ac9742204a 433 SMART SM00388 214 272 4.4E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS14780 f4ee5f80c224f760481dd4ac9742204a 433 SMART SM00387 310 419 2.2E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14780 f4ee5f80c224f760481dd4ac9742204a 433 Pfam PF00512 His Kinase A (phospho-acceptor) domain 215 271 1.7E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS14780 f4ee5f80c224f760481dd4ac9742204a 433 SUPERFAMILY SSF47384 197 270 2.55E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS14780 f4ee5f80c224f760481dd4ac9742204a 433 Gene3D G3DSA:1.10.287.130 204 268 9.3E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS14780 f4ee5f80c224f760481dd4ac9742204a 433 Pfam PF00672 HAMP domain 138 210 2.1E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS14780 f4ee5f80c224f760481dd4ac9742204a 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 355 4.1E-5 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS14780 f4ee5f80c224f760481dd4ac9742204a 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 392 4.1E-5 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS14780 f4ee5f80c224f760481dd4ac9742204a 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 4.1E-5 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS14780 f4ee5f80c224f760481dd4ac9742204a 433 SUPERFAMILY SSF55874 261 417 1.83E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14780 f4ee5f80c224f760481dd4ac9742204a 433 SMART SM00304 157 213 1.0E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS14780 f4ee5f80c224f760481dd4ac9742204a 433 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 310 417 2.4E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS02025 8a90bb20722ae940a0c7dfbb994b5e00 334 SUPERFAMILY SSF53335 79 216 2.0E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS02025 8a90bb20722ae940a0c7dfbb994b5e00 334 SUPERFAMILY SSF53335 270 321 2.0E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS02025 8a90bb20722ae940a0c7dfbb994b5e00 334 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 204 329 2.6E-16 T 06-07-2017 IPR019257 Histidine-specific methyltransferase, SAM-dependent SMD11_RS02025 8a90bb20722ae940a0c7dfbb994b5e00 334 PIRSF PIRSF018005 13 334 2.2E-66 T 06-07-2017 IPR017804 Methyltransferase EgtD-like SMD11_RS02025 8a90bb20722ae940a0c7dfbb994b5e00 334 Gene3D G3DSA:3.40.50.150 81 156 3.4E-6 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS15070 e4e46314ca671cfdb820c9167c721f9e 561 SMART SM00482 315 519 2.1E-11 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS15070 e4e46314ca671cfdb820c9167c721f9e 561 Gene3D G3DSA:3.30.70.370 482 542 6.8E-12 T 06-07-2017 SMD11_RS15070 e4e46314ca671cfdb820c9167c721f9e 561 Gene3D G3DSA:3.30.70.370 297 337 6.8E-12 T 06-07-2017 SMD11_RS15070 e4e46314ca671cfdb820c9167c721f9e 561 SUPERFAMILY SSF56672 158 544 5.11E-64 T 06-07-2017 SMD11_RS15070 e4e46314ca671cfdb820c9167c721f9e 561 Pfam PF00476 DNA polymerase family A 245 535 6.1E-29 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS15070 e4e46314ca671cfdb820c9167c721f9e 561 Gene3D G3DSA:1.10.150.20 338 481 1.1E-17 T 06-07-2017 SMD11_RS19155 3ee08fe845e54809c528661192d4d6d4 482 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 216 478 20.012 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 SMD11_RS19155 3ee08fe845e54809c528661192d4d6d4 482 Gene3D G3DSA:3.40.50.10260 3 222 1.1E-57 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SMD11_RS19155 3ee08fe845e54809c528661192d4d6d4 482 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 220 453 8.2E-46 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 SMD11_RS19155 3ee08fe845e54809c528661192d4d6d4 482 Pfam PF03853 YjeF-related protein N-terminus 25 182 2.3E-38 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SMD11_RS19155 3ee08fe845e54809c528661192d4d6d4 482 SUPERFAMILY SSF53613 217 474 1.0E-54 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS19155 3ee08fe845e54809c528661192d4d6d4 482 PIRSF PIRSF017184 1 478 6.0E-101 T 06-07-2017 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 SMD11_RS19155 3ee08fe845e54809c528661192d4d6d4 482 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 203 20.54 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SMD11_RS19155 3ee08fe845e54809c528661192d4d6d4 482 Gene3D G3DSA:3.40.1190.20 223 475 3.6E-80 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS19155 3ee08fe845e54809c528661192d4d6d4 482 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 20 202 9.1E-28 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SMD11_RS19155 3ee08fe845e54809c528661192d4d6d4 482 Pfam PF01256 Carbohydrate kinase 239 455 2.4E-50 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 SMD11_RS19155 3ee08fe845e54809c528661192d4d6d4 482 SUPERFAMILY SSF64153 4 237 1.83E-48 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 SMD11_RS16675 4dfaa5062494436a9591a579d8a1b8d5 170 SUPERFAMILY SSF143744 37 167 7.06E-35 T 06-07-2017 SMD11_RS16675 4dfaa5062494436a9591a579d8a1b8d5 170 Pfam PF03928 Haem-degrading 38 164 8.1E-30 T 06-07-2017 IPR005624 Haem-degrading SMD11_RS28315 37a0d445d9441592cb3fd9d5352f848e 366 SUPERFAMILY SSF48576 2 286 3.74E-41 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS28315 37a0d445d9441592cb3fd9d5352f848e 366 Gene3D G3DSA:1.10.600.10 2 283 1.3E-55 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS31590 98b3ec7b70fbe394ff769ce6f3add28a 187 Pfam PF11706 CGNR zinc finger 143 183 1.4E-9 T 06-07-2017 IPR021005 Zinc finger, CGNR SMD11_RS31590 98b3ec7b70fbe394ff769ce6f3add28a 187 Pfam PF07336 Putative stress-induced transcription regulator 15 138 4.4E-19 T 06-07-2017 IPR010852 Putative stress-induced transcription regulator SMD11_RS31590 98b3ec7b70fbe394ff769ce6f3add28a 187 SUPERFAMILY SSF160904 8 182 2.62E-33 T 06-07-2017 SMD11_RS31590 98b3ec7b70fbe394ff769ce6f3add28a 187 Gene3D G3DSA:1.10.3300.10 7 184 8.2E-36 T 06-07-2017 IPR023286 ABATE domain SMD11_RS17165 b4762b805276cdaa4f7c64dedbbe852d 185 Pfam PF13412 Winged helix-turn-helix DNA-binding 18 65 1.8E-14 T 06-07-2017 SMD11_RS17165 b4762b805276cdaa4f7c64dedbbe852d 185 SUPERFAMILY SSF54909 81 155 9.39E-14 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS17165 b4762b805276cdaa4f7c64dedbbe852d 185 Gene3D G3DSA:3.30.70.920 70 156 3.5E-20 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS17165 b4762b805276cdaa4f7c64dedbbe852d 185 Gene3D G3DSA:1.10.10.10 17 68 3.6E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17165 b4762b805276cdaa4f7c64dedbbe852d 185 Pfam PF01037 Lrp/AsnC ligand binding domain 91 155 3.0E-12 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS17165 b4762b805276cdaa4f7c64dedbbe852d 185 SMART SM00344 18 124 1.1E-23 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD11_RS17165 b4762b805276cdaa4f7c64dedbbe852d 185 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 45 64 8.5E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS17165 b4762b805276cdaa4f7c64dedbbe852d 185 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 34 8.5E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS17165 b4762b805276cdaa4f7c64dedbbe852d 185 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 45 8.5E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS17165 b4762b805276cdaa4f7c64dedbbe852d 185 SUPERFAMILY SSF46785 18 77 1.63E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21485 ab0d65c6f2de862459aa88ffa46542cf 379 SUPERFAMILY SSF50331 236 347 7.23E-12 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal SMD11_RS21485 ab0d65c6f2de862459aa88ffa46542cf 379 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS21485 ab0d65c6f2de862459aa88ffa46542cf 379 Pfam PF00005 ABC transporter 16 158 1.8E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS21485 ab0d65c6f2de862459aa88ffa46542cf 379 Pfam PF08402 TOBE domain 274 344 9.8E-9 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SMD11_RS21485 ab0d65c6f2de862459aa88ffa46542cf 379 SMART SM00382 25 209 3.7E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS21485 ab0d65c6f2de862459aa88ffa46542cf 379 SUPERFAMILY SSF52540 1 241 8.47E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21485 ab0d65c6f2de862459aa88ffa46542cf 379 Gene3D G3DSA:3.40.50.300 1 233 6.5E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03300 750ab2b4cba27bd6abf1291a2018c594 421 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 252 8.2E-55 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS03300 750ab2b4cba27bd6abf1291a2018c594 421 Gene3D G3DSA:3.40.47.10 2 263 2.4E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS03300 750ab2b4cba27bd6abf1291a2018c594 421 SMART SM00825 Beta-ketoacyl synthase 5 408 1.2E-11 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS03300 750ab2b4cba27bd6abf1291a2018c594 421 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 160 176 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS03300 750ab2b4cba27bd6abf1291a2018c594 421 SUPERFAMILY SSF53901 3 256 4.91E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS03300 750ab2b4cba27bd6abf1291a2018c594 421 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 260 374 3.2E-33 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS03300 750ab2b4cba27bd6abf1291a2018c594 421 Gene3D G3DSA:3.40.47.10 270 417 5.3E-50 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS03300 750ab2b4cba27bd6abf1291a2018c594 421 SUPERFAMILY SSF53901 219 417 7.82E-64 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS13385 e0f057640c5c6ab5bff16d41892a6d9f 418 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 3 384 2.5E-132 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD11_RS13385 e0f057640c5c6ab5bff16d41892a6d9f 418 Gene3D G3DSA:3.40.50.800 301 405 4.9E-18 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS13385 e0f057640c5c6ab5bff16d41892a6d9f 418 SUPERFAMILY SSF55681 9 296 9.12E-85 T 06-07-2017 SMD11_RS13385 e0f057640c5c6ab5bff16d41892a6d9f 418 SUPERFAMILY SSF52954 299 409 3.93E-19 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS13385 e0f057640c5c6ab5bff16d41892a6d9f 418 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 93 298 9.1E-28 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS13385 e0f057640c5c6ab5bff16d41892a6d9f 418 Pfam PF03129 Anticodon binding domain 311 385 4.4E-8 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS13385 e0f057640c5c6ab5bff16d41892a6d9f 418 Gene3D G3DSA:3.30.930.10 9 299 1.7E-94 T 06-07-2017 SMD11_RS13385 e0f057640c5c6ab5bff16d41892a6d9f 418 PRINTS PR01047 Threonyl-tRNA synthetase signature 130 153 2.7E-45 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD11_RS13385 e0f057640c5c6ab5bff16d41892a6d9f 418 PRINTS PR01047 Threonyl-tRNA synthetase signature 277 290 2.7E-45 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD11_RS13385 e0f057640c5c6ab5bff16d41892a6d9f 418 PRINTS PR01047 Threonyl-tRNA synthetase signature 234 262 2.7E-45 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD11_RS13385 e0f057640c5c6ab5bff16d41892a6d9f 418 PRINTS PR01047 Threonyl-tRNA synthetase signature 304 316 2.7E-45 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD11_RS13385 e0f057640c5c6ab5bff16d41892a6d9f 418 PRINTS PR01047 Threonyl-tRNA synthetase signature 97 125 2.7E-45 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SMD11_RS27220 99bdc2be674483c6da357e22ca65f251 409 Pfam PF03993 Domain of Unknown Function (DUF349) 168 241 5.0E-22 T 06-07-2017 IPR007139 Protein of unknown function DUF349 SMD11_RS27220 99bdc2be674483c6da357e22ca65f251 409 Pfam PF03993 Domain of Unknown Function (DUF349) 91 164 1.4E-13 T 06-07-2017 IPR007139 Protein of unknown function DUF349 SMD11_RS27220 99bdc2be674483c6da357e22ca65f251 409 Pfam PF03993 Domain of Unknown Function (DUF349) 245 318 9.1E-22 T 06-07-2017 IPR007139 Protein of unknown function DUF349 SMD11_RS27220 99bdc2be674483c6da357e22ca65f251 409 Gene3D G3DSA:1.20.120.20 314 406 1.8E-4 T 06-07-2017 SMD11_RS33190 348903b1418c823ff799a473a7aad67d 165 Gene3D G3DSA:3.90.79.10 4 133 1.6E-20 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS33190 348903b1418c823ff799a473a7aad67d 165 SUPERFAMILY SSF55811 4 132 1.35E-19 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS33190 348903b1418c823ff799a473a7aad67d 165 Pfam PF00293 NUDIX domain 7 131 1.1E-14 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS33190 348903b1418c823ff799a473a7aad67d 165 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD11_RS33190 348903b1418c823ff799a473a7aad67d 165 PRINTS PR00502 NUDIX hydrolase family signature 52 67 1.7E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS33190 348903b1418c823ff799a473a7aad67d 165 PRINTS PR00502 NUDIX hydrolase family signature 38 52 1.7E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 SUPERFAMILY SSF55874 23 242 9.3E-60 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 Gene3D G3DSA:3.40.50.670 465 685 4.1E-74 T 06-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 SMART SM00433 52 697 8.9E-281 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 Pfam PF00204 DNA gyrase B 259 451 1.7E-55 T 06-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 48 158 1.2E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 SUPERFAMILY SSF56719 455 697 4.97E-75 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 Gene3D G3DSA:3.30.565.10 23 244 9.0E-81 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 Pfam PF01751 Toprim domain 480 580 1.2E-14 T 06-07-2017 IPR006171 Toprim domain SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR00418 DNA topoisomerase II family signature 636 652 7.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR00418 DNA topoisomerase II family signature 87 100 7.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR00418 DNA topoisomerase II family signature 325 338 7.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR00418 DNA topoisomerase II family signature 547 563 7.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR00418 DNA topoisomerase II family signature 52 67 7.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR00418 DNA topoisomerase II family signature 565 582 7.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR00418 DNA topoisomerase II family signature 130 144 7.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR00418 DNA topoisomerase II family signature 481 495 7.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR00418 DNA topoisomerase II family signature 585 597 7.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 SUPERFAMILY SSF54211 259 451 1.86E-39 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 636 692 1.6E-24 T 06-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 ProSitePatterns PS00177 DNA topoisomerase II signature. 483 491 - T 06-07-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 SMART SM00387 48 208 4.6E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR01159 DNA gyrase subunit B signature 369 385 1.7E-36 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR01159 DNA gyrase subunit B signature 531 540 1.7E-36 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR01159 DNA gyrase subunit B signature 258 280 1.7E-36 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR01159 DNA gyrase subunit B signature 657 669 1.7E-36 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR01159 DNA gyrase subunit B signature 23 33 1.7E-36 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR01159 DNA gyrase subunit B signature 214 229 1.7E-36 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR01159 DNA gyrase subunit B signature 435 455 1.7E-36 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR01159 DNA gyrase subunit B signature 229 242 1.7E-36 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 PRINTS PR01159 DNA gyrase subunit B signature 673 689 1.7E-36 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SMD11_RS08695 48500aeb56690c26e83627cbc23ba6a0 706 Gene3D G3DSA:3.30.230.10 258 451 1.1E-49 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS22680 dcb7f0b5cc81e8d861d749cfe86fa05c 283 SMART SM00530 17 72 3.5E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS22680 dcb7f0b5cc81e8d861d749cfe86fa05c 283 Gene3D G3DSA:1.10.260.40 6 74 1.3E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS22680 dcb7f0b5cc81e8d861d749cfe86fa05c 283 SUPERFAMILY SSF47413 10 74 1.21E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS22680 dcb7f0b5cc81e8d861d749cfe86fa05c 283 Pfam PF13560 Helix-turn-helix domain 13 74 2.5E-12 T 06-07-2017 SMD11_RS07370 280b83d17c51e2d6ae83c6357196f991 325 SUPERFAMILY SSF52540 2 205 3.92E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07370 280b83d17c51e2d6ae83c6357196f991 325 SMART SM00382 27 200 1.8E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS07370 280b83d17c51e2d6ae83c6357196f991 325 Pfam PF00005 ABC transporter 18 148 6.3E-19 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS07370 280b83d17c51e2d6ae83c6357196f991 325 Gene3D G3DSA:3.40.50.300 3 204 1.7E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15425 644e606eb23ee2d07de431788e7f75e8 290 SMART SM00644 27 178 1.2E-10 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS15425 644e606eb23ee2d07de431788e7f75e8 290 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 39 177 1.6E-10 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS15425 644e606eb23ee2d07de431788e7f75e8 290 SUPERFAMILY SSF55846 18 189 1.18E-19 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS15425 644e606eb23ee2d07de431788e7f75e8 290 Gene3D G3DSA:3.40.80.10 87 190 2.7E-14 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS26170 d938c0bf937120419f56ec3a18365dc8 326 SUPERFAMILY SSF52540 9 229 2.92E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26170 d938c0bf937120419f56ec3a18365dc8 326 SMART SM00382 30 213 9.3E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS26170 d938c0bf937120419f56ec3a18365dc8 326 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS26170 d938c0bf937120419f56ec3a18365dc8 326 Gene3D G3DSA:3.40.50.300 5 235 1.2E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26170 d938c0bf937120419f56ec3a18365dc8 326 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 13 308 1.8E-100 T 06-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMD11_RS26170 d938c0bf937120419f56ec3a18365dc8 326 Pfam PF00005 ABC transporter 21 164 9.3E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS03690 c89821ee90162af75532baf45acaf3fe 469 SMART SM00100 96 219 4.2E-15 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain SMD11_RS03690 c89821ee90162af75532baf45acaf3fe 469 Pfam PF00027 Cyclic nucleotide-binding domain 116 203 2.1E-17 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain SMD11_RS03690 c89821ee90162af75532baf45acaf3fe 469 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 124 140 - T 06-07-2017 IPR018488 Cyclic nucleotide-binding, conserved site SMD11_RS03690 c89821ee90162af75532baf45acaf3fe 469 SUPERFAMILY SSF51206 88 219 3.4E-25 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like SMD11_RS03690 c89821ee90162af75532baf45acaf3fe 469 Gene3D G3DSA:2.60.120.10 92 216 1.2E-23 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS15050 3452d79a5b9071097f9511a3430f6b75 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 3.4E-22 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS15050 3452d79a5b9071097f9511a3430f6b75 54 Pfam PF00471 Ribosomal protein L33 9 54 1.5E-16 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS15050 3452d79a5b9071097f9511a3430f6b75 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 14.658 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS15050 3452d79a5b9071097f9511a3430f6b75 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 06-07-2017 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS15050 3452d79a5b9071097f9511a3430f6b75 54 SUPERFAMILY SSF57829 4 54 1.95E-17 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 SMD11_RS26760 2a131ad177305e2ee39687d626e6b869 285 Gene3D G3DSA:3.40.50.720 3 190 2.9E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS26760 2a131ad177305e2ee39687d626e6b869 285 Gene3D G3DSA:1.10.1040.10 191 285 6.0E-34 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS26760 2a131ad177305e2ee39687d626e6b869 285 SUPERFAMILY SSF51735 5 186 4.51E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS26760 2a131ad177305e2ee39687d626e6b869 285 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 186 2.2E-60 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS26760 2a131ad177305e2ee39687d626e6b869 285 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 189 285 4.4E-33 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS26760 2a131ad177305e2ee39687d626e6b869 285 PIRSF PIRSF000105 2 285 8.7E-79 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 SMD11_RS26760 2a131ad177305e2ee39687d626e6b869 285 SUPERFAMILY SSF48179 189 285 4.42E-30 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS03895 5aa18141d1c7c55422e06cb75d269f7d 135 Pfam PF07883 Cupin domain 41 108 3.4E-12 T 06-07-2017 IPR013096 Cupin 2, conserved barrel SMD11_RS03895 5aa18141d1c7c55422e06cb75d269f7d 135 Gene3D G3DSA:2.60.120.10 4 130 1.9E-27 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS03895 5aa18141d1c7c55422e06cb75d269f7d 135 SUPERFAMILY SSF51182 12 131 8.6E-25 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS08965 090633397fe70fd3e0aca174965130c9 306 SUPERFAMILY SSF48239 45 185 9.99E-12 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS08965 090633397fe70fd3e0aca174965130c9 306 SUPERFAMILY SSF48239 253 304 9.99E-12 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS08965 090633397fe70fd3e0aca174965130c9 306 Gene3D G3DSA:1.50.10.20 252 305 2.2E-5 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 SMART SM00825 Beta-ketoacyl synthase 9 432 1.5E-143 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 Gene3D G3DSA:3.40.50.720 1401 1613 5.3E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 SUPERFAMILY SSF55048 665 730 4.05E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 Gene3D G3DSA:3.40.366.10 730 844 1.1E-59 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 Gene3D G3DSA:3.40.366.10 540 661 1.1E-59 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 256 1.4E-67 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 Gene3D G3DSA:3.40.47.10 4 268 1.8E-74 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 SMART SM00826 905 1067 1.3E-29 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 SUPERFAMILY SSF53901 4 377 4.08E-82 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 SUPERFAMILY SSF52151 731 824 1.26E-54 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 SUPERFAMILY SSF52151 543 667 1.26E-54 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 Pfam PF14765 Polyketide synthase dehydratase 905 1185 3.3E-52 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 Pfam PF00550 Phosphopantetheine attachment site 1678 1742 1.1E-6 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 Pfam PF08659 KR domain 1403 1581 8.0E-57 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 Pfam PF00698 Acyl transferase domain 543 858 1.0E-76 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 SUPERFAMILY SSF51735 1398 1640 6.54E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 Gene3D G3DSA:1.10.1200.10 1669 1744 8.9E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 Gene3D G3DSA:3.40.47.10 269 433 2.4E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 SMART SM00823 Phosphopantetheine attachment site 1675 1746 7.1E-7 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1403 1583 1.1E-41 T 06-07-2017 SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 264 378 1.7E-37 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 SUPERFAMILY SSF47336 1670 1746 5.76E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 383 495 1.7E-12 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 Gene3D G3DSA:3.30.70.250 665 729 7.1E-6 T 06-07-2017 SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 545 840 4.7E-87 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS34155 6d4c3afd23cd1f03c3c79f036e495341 1757 SUPERFAMILY SSF51735 1192 1387 1.73E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30885 1f7420d31fb6bb5635a529c391694724 471 SUPERFAMILY SSF49384 39 142 2.37E-28 T 06-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 SMD11_RS30885 1f7420d31fb6bb5635a529c391694724 471 Gene3D G3DSA:2.60.40.290 42 143 2.2E-30 T 06-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 SMD11_RS30885 1f7420d31fb6bb5635a529c391694724 471 Pfam PF00553 Cellulose binding domain 44 142 9.5E-22 T 06-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMD11_RS30885 1f7420d31fb6bb5635a529c391694724 471 Pfam PF00704 Glycosyl hydrolases family 18 236 437 2.1E-8 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 SMD11_RS30885 1f7420d31fb6bb5635a529c391694724 471 Gene3D G3DSA:3.20.20.80 217 441 2.2E-9 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS30885 1f7420d31fb6bb5635a529c391694724 471 SMART SM00637 42 142 7.9E-28 T 06-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 SMD11_RS30885 1f7420d31fb6bb5635a529c391694724 471 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 107 120 - T 06-07-2017 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 SMD11_RS30885 1f7420d31fb6bb5635a529c391694724 471 SUPERFAMILY SSF51445 180 441 1.52E-21 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS26815 3288ba6585dbc564c15e7c52913c29fd 381 Pfam PF00202 Aminotransferase class-III 9 368 1.3E-102 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS26815 3288ba6585dbc564c15e7c52913c29fd 381 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 1 373 41.467 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 SMD11_RS26815 3288ba6585dbc564c15e7c52913c29fd 381 Gene3D G3DSA:3.90.1150.10 268 374 8.0E-36 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS26815 3288ba6585dbc564c15e7c52913c29fd 381 Gene3D G3DSA:3.40.640.10 43 267 3.1E-84 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS26815 3288ba6585dbc564c15e7c52913c29fd 381 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 1 372 4.2E-136 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 SMD11_RS26815 3288ba6585dbc564c15e7c52913c29fd 381 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 200 237 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS26815 3288ba6585dbc564c15e7c52913c29fd 381 SUPERFAMILY SSF53383 3 373 8.53E-119 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS33325 e2e310af63708df33157b1e7d5ce8550 377 Gene3D G3DSA:3.60.130.10 121 368 2.8E-25 T 06-07-2017 SMD11_RS33325 e2e310af63708df33157b1e7d5ce8550 377 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 110 351 1.6E-28 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMD11_RS33325 e2e310af63708df33157b1e7d5ce8550 377 SUPERFAMILY SSF51197 74 361 8.7E-34 T 06-07-2017 SMD11_RS33325 e2e310af63708df33157b1e7d5ce8550 377 Pfam PF06155 Protein of unknown function (DUF971) 19 86 1.1E-6 T 06-07-2017 IPR010376 Domain of unknown function DUF971 Reactome: R-HSA-71262 SMD11_RS11895 ba3b102c5033e490571c3d39cdcc5517 335 Pfam PF00583 Acetyltransferase (GNAT) family 266 322 2.3E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS11895 ba3b102c5033e490571c3d39cdcc5517 335 Gene3D G3DSA:3.40.630.30 190 332 1.8E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS11895 ba3b102c5033e490571c3d39cdcc5517 335 SUPERFAMILY SSF55729 231 328 1.65E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS34005 ed67b5771b99af838565af1c6a74b79c 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 8.0E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS34005 ed67b5771b99af838565af1c6a74b79c 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 8.0E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS34005 ed67b5771b99af838565af1c6a74b79c 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 50 1.9E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS34005 ed67b5771b99af838565af1c6a74b79c 194 Gene3D G3DSA:1.10.10.60 1 43 1.4E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS34005 ed67b5771b99af838565af1c6a74b79c 194 SUPERFAMILY SSF48498 63 177 1.56E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS34005 ed67b5771b99af838565af1c6a74b79c 194 Gene3D G3DSA:1.10.357.10 50 179 1.6E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS34005 ed67b5771b99af838565af1c6a74b79c 194 Pfam PF16859 Bacterial transcriptional repressor C-terminal 64 172 1.6E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS34005 ed67b5771b99af838565af1c6a74b79c 194 SUPERFAMILY SSF46689 3 55 4.73E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS32430 eebf484d0ee7f264d8287c776ed94993 526 Gene3D G3DSA:1.10.3140.10 23 161 2.6E-55 T 06-07-2017 SMD11_RS32430 eebf484d0ee7f264d8287c776ed94993 526 Gene3D G3DSA:1.20.140.10 282 482 4.2E-28 T 06-07-2017 SMD11_RS32430 eebf484d0ee7f264d8287c776ed94993 526 Gene3D G3DSA:2.40.110.10 162 281 3.0E-44 T 06-07-2017 SMD11_RS32430 eebf484d0ee7f264d8287c776ed94993 526 SUPERFAMILY SSF47203 281 487 1.3E-37 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS32430 eebf484d0ee7f264d8287c776ed94993 526 PIRSF PIRSF000331 22 509 3.0E-170 T 06-07-2017 IPR004925 HpaB/PvcC/4-BUDH SMD11_RS32430 eebf484d0ee7f264d8287c776ed94993 526 PIRSF PIRSF500125 10 522 2.0E-216 T 06-07-2017 IPR024677 4-HPA 3-monooxygenase large component/Pyoverdin chromophore biosynthetic protein SMD11_RS32430 eebf484d0ee7f264d8287c776ed94993 526 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 26 288 6.0E-92 T 06-07-2017 IPR024674 HpaB/PvcC/4-BUDH N-terminal SMD11_RS32430 eebf484d0ee7f264d8287c776ed94993 526 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 296 495 1.8E-53 T 06-07-2017 IPR024719 HpaB/PvcC/4-BUDH C-terminal SMD11_RS32430 eebf484d0ee7f264d8287c776ed94993 526 SUPERFAMILY SSF56645 24 289 1.07E-82 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS16100 957450cec4c3d81bb9658b32af5ffed0 548 SUPERFAMILY SSF103473 23 222 7.06E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS16100 957450cec4c3d81bb9658b32af5ffed0 548 SUPERFAMILY SSF103473 491 517 7.06E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS16100 957450cec4c3d81bb9658b32af5ffed0 548 SUPERFAMILY SSF103473 271 443 7.06E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS16100 957450cec4c3d81bb9658b32af5ffed0 548 Pfam PF07690 Major Facilitator Superfamily 38 433 2.1E-48 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS16100 957450cec4c3d81bb9658b32af5ffed0 548 Gene3D G3DSA:1.20.1250.20 498 520 4.3E-21 T 06-07-2017 SMD11_RS16100 957450cec4c3d81bb9658b32af5ffed0 548 Gene3D G3DSA:1.20.1250.20 277 460 4.3E-21 T 06-07-2017 SMD11_RS16100 957450cec4c3d81bb9658b32af5ffed0 548 Gene3D G3DSA:1.20.1250.20 38 208 2.2E-31 T 06-07-2017 SMD11_RS16100 957450cec4c3d81bb9658b32af5ffed0 548 PRINTS PR01036 Tetracycline resistance protein TetB signature 37 61 1.3E-9 T 06-07-2017 SMD11_RS16100 957450cec4c3d81bb9658b32af5ffed0 548 PRINTS PR01036 Tetracycline resistance protein TetB signature 158 182 1.3E-9 T 06-07-2017 SMD11_RS16100 957450cec4c3d81bb9658b32af5ffed0 548 PRINTS PR01036 Tetracycline resistance protein TetB signature 424 443 1.3E-9 T 06-07-2017 SMD11_RS16100 957450cec4c3d81bb9658b32af5ffed0 548 PRINTS PR01036 Tetracycline resistance protein TetB signature 128 148 1.3E-9 T 06-07-2017 SMD11_RS30875 375b2727b578bc90e9e3beab6bf1fafd 397 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 13 141 3.8E-14 T 06-07-2017 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 SMD11_RS30875 375b2727b578bc90e9e3beab6bf1fafd 397 Gene3D G3DSA:3.40.50.720 13 172 1.7E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30875 375b2727b578bc90e9e3beab6bf1fafd 397 SUPERFAMILY SSF51735 11 182 7.75E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03995 0c7444150d2b26112ee3714627cd2412 761 SUPERFAMILY SSF48208 263 729 1.87E-28 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD11_RS03995 0c7444150d2b26112ee3714627cd2412 761 Gene3D G3DSA:1.20.1610.10 436 604 1.1E-48 T 06-07-2017 SMD11_RS03995 0c7444150d2b26112ee3714627cd2412 761 Pfam PF07971 Glycosyl hydrolase family 92 233 743 4.4E-140 T 06-07-2017 IPR012939 Glycosyl hydrolase family 92 SMD11_RS03995 0c7444150d2b26112ee3714627cd2412 761 Gene3D G3DSA:1.20.1050.60 339 428 3.1E-24 T 06-07-2017 SMD11_RS03995 0c7444150d2b26112ee3714627cd2412 761 Gene3D G3DSA:2.70.98.10 20 315 2.0E-95 T 06-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 SMD11_RS03995 0c7444150d2b26112ee3714627cd2412 761 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 17 746 1.6E-164 T 06-07-2017 IPR005887 Alpha-1,2-mannosidase, putative SMD11_RS03995 0c7444150d2b26112ee3714627cd2412 761 Gene3D G3DSA:3.30.2080.10 605 755 4.5E-49 T 06-07-2017 SMD11_RS15535 18e8f94fa4692b7557038e04bc74d935 511 Pfam PF02374 Anion-transporting ATPase 27 298 3.7E-25 T 06-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 SMD11_RS15535 18e8f94fa4692b7557038e04bc74d935 511 Gene3D G3DSA:3.40.50.300 226 303 5.7E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15535 18e8f94fa4692b7557038e04bc74d935 511 Gene3D G3DSA:3.40.50.300 23 185 5.7E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15535 18e8f94fa4692b7557038e04bc74d935 511 SUPERFAMILY SSF52540 24 197 1.2E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15535 18e8f94fa4692b7557038e04bc74d935 511 SUPERFAMILY SSF52540 239 300 1.2E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25645 3a3f3fe903517df9c24c3ce7d53f3713 263 SMART SM00382 29 253 9.3E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS25645 3a3f3fe903517df9c24c3ce7d53f3713 263 Gene3D G3DSA:3.40.50.300 6 230 5.0E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25645 3a3f3fe903517df9c24c3ce7d53f3713 263 SUPERFAMILY SSF52540 4 230 3.86E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25645 3a3f3fe903517df9c24c3ce7d53f3713 263 Pfam PF00005 ABC transporter 21 171 1.5E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS26665 22c8e11d23ae4b4c21214e5189199ada 261 SUPERFAMILY SSF51735 13 253 4.93E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS26665 22c8e11d23ae4b4c21214e5189199ada 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS26665 22c8e11d23ae4b4c21214e5189199ada 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS26665 22c8e11d23ae4b4c21214e5189199ada 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS26665 22c8e11d23ae4b4c21214e5189199ada 261 Gene3D G3DSA:3.40.50.720 9 253 1.1E-86 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS26665 22c8e11d23ae4b4c21214e5189199ada 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 253 9.0E-71 T 06-07-2017 SMD11_RS26665 22c8e11d23ae4b4c21214e5189199ada 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 2.3E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS26665 22c8e11d23ae4b4c21214e5189199ada 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.3E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS26665 22c8e11d23ae4b4c21214e5189199ada 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.3E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS26665 22c8e11d23ae4b4c21214e5189199ada 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.3E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS26665 22c8e11d23ae4b4c21214e5189199ada 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.3E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS26665 22c8e11d23ae4b4c21214e5189199ada 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.3E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 PRINTS PR00992 Alanine racemase signature 127 139 1.2E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 PRINTS PR00992 Alanine racemase signature 30 46 1.2E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 PRINTS PR00992 Alanine racemase signature 66 84 1.2E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 PRINTS PR00992 Alanine racemase signature 265 280 1.2E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 PRINTS PR00992 Alanine racemase signature 303 320 1.2E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 PRINTS PR00992 Alanine racemase signature 358 371 1.2E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 PRINTS PR00992 Alanine racemase signature 164 175 1.2E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 PRINTS PR00992 Alanine racemase signature 282 297 1.2E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 PRINTS PR00992 Alanine racemase signature 207 234 1.2E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 SUPERFAMILY SSF51419 12 250 3.4E-66 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 35 45 - T 06-07-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 SUPERFAMILY SSF50621 242 379 2.02E-48 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 Gene3D G3DSA:3.20.20.10 14 227 1.7E-74 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 TIGRFAM TIGR00492 alr: alanine racemase 9 376 2.0E-92 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 SMART SM01005 249 376 3.4E-65 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 Gene3D G3DSA:2.40.37.10 228 379 2.6E-58 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 Pfam PF01168 Alanine racemase, N-terminal domain 12 234 5.8E-68 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 Hamap MF_01201 Alanine racemase. 5 376 32.589 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS19160 bb20497b89d307d1977abd259da735b8 401 Pfam PF00842 Alanine racemase, C-terminal domain 249 375 3.1E-39 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS20840 4179d803553e49198e9a2f7c87949d1a 1670 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 89 1663 0.0 T 06-07-2017 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 SMD11_RS20840 4179d803553e49198e9a2f7c87949d1a 1670 Gene3D G3DSA:3.40.50.720 996 1107 1.0E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20840 4179d803553e49198e9a2f7c87949d1a 1670 Gene3D G3DSA:3.40.50.720 1164 1242 1.0E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20840 4179d803553e49198e9a2f7c87949d1a 1670 SUPERFAMILY SSF53223 808 994 1.73E-22 T 06-07-2017 SMD11_RS20840 4179d803553e49198e9a2f7c87949d1a 1670 PIRSF PIRSF036761 3 1670 0.0 T 06-07-2017 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 SMD11_RS20840 4179d803553e49198e9a2f7c87949d1a 1670 SUPERFAMILY SSF51735 999 1101 8.66E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20840 4179d803553e49198e9a2f7c87949d1a 1670 SUPERFAMILY SSF51735 1139 1348 8.66E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS22815 1295ed7c3ba5c849d0be0c5756867ab0 593 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 32 592 54.104 T 06-07-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD11_RS22815 1295ed7c3ba5c849d0be0c5756867ab0 593 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 64 80 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD11_RS22815 1295ed7c3ba5c849d0be0c5756867ab0 593 SMART SM00917 458 591 1.6E-36 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD11_RS22815 1295ed7c3ba5c849d0be0c5756867ab0 593 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 269 282 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD11_RS22815 1295ed7c3ba5c849d0be0c5756867ab0 593 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 31 592 5.4E-254 T 06-07-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD11_RS22815 1295ed7c3ba5c849d0be0c5756867ab0 593 SUPERFAMILY SSF110921 487 590 1.57E-34 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD11_RS22815 1295ed7c3ba5c849d0be0c5756867ab0 593 Pfam PF00682 HMGL-like 57 337 5.7E-74 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMD11_RS22815 1295ed7c3ba5c849d0be0c5756867ab0 593 Gene3D G3DSA:3.20.20.70 35 429 7.0E-143 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS22815 1295ed7c3ba5c849d0be0c5756867ab0 593 SUPERFAMILY SSF51569 46 356 3.11E-94 T 06-07-2017 SMD11_RS22815 1295ed7c3ba5c849d0be0c5756867ab0 593 Pfam PF08502 LeuA allosteric (dimerisation) domain 458 590 3.1E-34 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD11_RS22815 1295ed7c3ba5c849d0be0c5756867ab0 593 SUPERFAMILY SSF89000 424 473 5.89E-16 T 06-07-2017 SMD11_RS13595 bc0453a208a2bc78d52972b6b657b583 207 PIRSF PIRSF000190 1 207 1.4E-79 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD11_RS13595 bc0453a208a2bc78d52972b6b657b583 207 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 177 190 - T 06-07-2017 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD11_RS13595 bc0453a208a2bc78d52972b6b657b583 207 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 2 207 2.4E-79 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD11_RS13595 bc0453a208a2bc78d52972b6b657b583 207 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 29 112 1.5E-22 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD11_RS13595 bc0453a208a2bc78d52972b6b657b583 207 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 4 207 38.953 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD11_RS13595 bc0453a208a2bc78d52972b6b657b583 207 Gene3D G3DSA:2.30.110.10 11 207 3.7E-83 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS13595 bc0453a208a2bc78d52972b6b657b583 207 SUPERFAMILY SSF50475 7 207 6.25E-67 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS13595 bc0453a208a2bc78d52972b6b657b583 207 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 167 207 1.3E-19 T 06-07-2017 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD11_RS15745 beda32a83ef8f1a1594335fa3da0217d 332 Pfam PF16884 N-terminal domain of oxidoreductase 10 103 1.2E-26 T 06-07-2017 SMD11_RS15745 beda32a83ef8f1a1594335fa3da0217d 332 SMART SM00829 38 328 4.2E-7 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS15745 beda32a83ef8f1a1594335fa3da0217d 332 SUPERFAMILY SSF50129 4 135 4.27E-31 T 06-07-2017 IPR011032 GroES-like SMD11_RS15745 beda32a83ef8f1a1594335fa3da0217d 332 Gene3D G3DSA:3.40.50.720 137 297 1.5E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS15745 beda32a83ef8f1a1594335fa3da0217d 332 Gene3D G3DSA:3.90.180.10 3 136 1.7E-43 T 06-07-2017 IPR011032 GroES-like SMD11_RS15745 beda32a83ef8f1a1594335fa3da0217d 332 Pfam PF00107 Zinc-binding dehydrogenase 154 286 4.0E-20 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS15745 beda32a83ef8f1a1594335fa3da0217d 332 SUPERFAMILY SSF51735 120 296 5.96E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS07610 d6533ae0016cb9f7c08a6f3496690b0b 120 SUPERFAMILY SSF46785 6 88 5.16E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07610 d6533ae0016cb9f7c08a6f3496690b0b 120 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 5.0E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS07610 d6533ae0016cb9f7c08a6f3496690b0b 120 Gene3D G3DSA:1.10.10.10 4 77 1.3E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07610 d6533ae0016cb9f7c08a6f3496690b0b 120 SMART SM00345 17 76 2.5E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS23485 6057b34eb54301fecec13e355defb2d6 422 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 127 168 5.7E-8 T 06-07-2017 IPR001330 PFTB repeat GO:0003824 SMD11_RS23485 6057b34eb54301fecec13e355defb2d6 422 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 72 121 0.23 T 06-07-2017 IPR001330 PFTB repeat GO:0003824 SMD11_RS23485 6057b34eb54301fecec13e355defb2d6 422 Gene3D G3DSA:1.50.10.20 71 179 5.4E-20 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS23485 6057b34eb54301fecec13e355defb2d6 422 SUPERFAMILY SSF48239 260 324 4.08E-22 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS23485 6057b34eb54301fecec13e355defb2d6 422 SUPERFAMILY SSF48239 66 172 4.08E-22 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS08420 3e28d6a3c0d1f300eac8feb7f6542e5f 627 SUPERFAMILY SSF56322 98 388 1.7E-62 T 06-07-2017 IPR005801 ADC synthase GO:0009058 SMD11_RS08420 3e28d6a3c0d1f300eac8feb7f6542e5f 627 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 474 488 5.7E-5 T 06-07-2017 SMD11_RS08420 3e28d6a3c0d1f300eac8feb7f6542e5f 627 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 510 526 5.7E-5 T 06-07-2017 SMD11_RS08420 3e28d6a3c0d1f300eac8feb7f6542e5f 627 Gene3D G3DSA:3.40.50.880 435 619 4.4E-28 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS08420 3e28d6a3c0d1f300eac8feb7f6542e5f 627 PRINTS PR00096 Glutamine amidotransferase superfamily signature 477 486 3.2E-8 T 06-07-2017 SMD11_RS08420 3e28d6a3c0d1f300eac8feb7f6542e5f 627 PRINTS PR00096 Glutamine amidotransferase superfamily signature 596 609 3.2E-8 T 06-07-2017 SMD11_RS08420 3e28d6a3c0d1f300eac8feb7f6542e5f 627 PRINTS PR00096 Glutamine amidotransferase superfamily signature 510 521 3.2E-8 T 06-07-2017 SMD11_RS08420 3e28d6a3c0d1f300eac8feb7f6542e5f 627 Gene3D G3DSA:3.60.120.10 115 389 3.5E-57 T 06-07-2017 IPR005801 ADC synthase GO:0009058 SMD11_RS08420 3e28d6a3c0d1f300eac8feb7f6542e5f 627 Pfam PF00425 chorismate binding enzyme 122 380 3.8E-45 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal SMD11_RS08420 3e28d6a3c0d1f300eac8feb7f6542e5f 627 SUPERFAMILY SSF52317 431 618 1.47E-24 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS08420 3e28d6a3c0d1f300eac8feb7f6542e5f 627 Pfam PF00117 Glutamine amidotransferase class-I 438 615 7.6E-21 T 06-07-2017 IPR017926 Glutamine amidotransferase SMD11_RS08420 3e28d6a3c0d1f300eac8feb7f6542e5f 627 PRINTS PR00097 Anthranilate synthase component II signature 436 450 1.2E-6 T 06-07-2017 SMD11_RS08420 3e28d6a3c0d1f300eac8feb7f6542e5f 627 PRINTS PR00097 Anthranilate synthase component II signature 510 521 1.2E-6 T 06-07-2017 SMD11_RS08420 3e28d6a3c0d1f300eac8feb7f6542e5f 627 PRINTS PR00097 Anthranilate synthase component II signature 596 609 1.2E-6 T 06-07-2017 SMD11_RS14755 1fade81ad82f76b3724371a5e0596bb4 576 SUPERFAMILY SSF55874 255 374 1.45E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14755 1fade81ad82f76b3724371a5e0596bb4 576 Gene3D G3DSA:3.30.565.10 244 376 7.6E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14755 1fade81ad82f76b3724371a5e0596bb4 576 Pfam PF07730 Histidine kinase 172 236 3.1E-12 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS23230 5ff5ec3c535aa8bc2ef078e61cf3f631 225 Gene3D G3DSA:1.10.10.10 129 221 3.9E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23230 5ff5ec3c535aa8bc2ef078e61cf3f631 225 SUPERFAMILY SSF52172 3 191 1.51E-33 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS23230 5ff5ec3c535aa8bc2ef078e61cf3f631 225 Gene3D G3DSA:3.40.50.2300 1 128 1.5E-37 T 06-07-2017 SMD11_RS23230 5ff5ec3c535aa8bc2ef078e61cf3f631 225 Pfam PF00072 Response regulator receiver domain 5 121 3.4E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS23230 5ff5ec3c535aa8bc2ef078e61cf3f631 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 214 2.8E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23230 5ff5ec3c535aa8bc2ef078e61cf3f631 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 1.6E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23230 5ff5ec3c535aa8bc2ef078e61cf3f631 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 1.6E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23230 5ff5ec3c535aa8bc2ef078e61cf3f631 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 1.6E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23230 5ff5ec3c535aa8bc2ef078e61cf3f631 225 SMART SM00421 157 214 2.2E-25 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23230 5ff5ec3c535aa8bc2ef078e61cf3f631 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS23230 5ff5ec3c535aa8bc2ef078e61cf3f631 225 SMART SM00448 3 120 2.1E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS23545 687b7bedf66fa1a35e8c46d6fc916737 359 SUPERFAMILY SSF48208 29 342 8.96E-38 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD11_RS23545 687b7bedf66fa1a35e8c46d6fc916737 359 Gene3D G3DSA:1.50.10.20 269 336 9.2E-15 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS23545 687b7bedf66fa1a35e8c46d6fc916737 359 Gene3D G3DSA:1.50.10.20 28 229 9.2E-15 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS20420 ff5a4ef7586ca6e4018970c352c82ded 85 Pfam PF00196 Bacterial regulatory proteins, luxR family 13 64 2.5E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20420 ff5a4ef7586ca6e4018970c352c82ded 85 SUPERFAMILY SSF46894 6 66 4.08E-16 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS20420 ff5a4ef7586ca6e4018970c352c82ded 85 Gene3D G3DSA:1.10.10.10 9 66 1.2E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20420 ff5a4ef7586ca6e4018970c352c82ded 85 SMART SM00421 11 68 3.4E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20420 ff5a4ef7586ca6e4018970c352c82ded 85 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 44 56 1.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20420 ff5a4ef7586ca6e4018970c352c82ded 85 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 14 28 1.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20420 ff5a4ef7586ca6e4018970c352c82ded 85 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 28 44 1.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS20420 ff5a4ef7586ca6e4018970c352c82ded 85 ProSitePatterns PS00622 LuxR-type HTH domain signature. 28 55 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS06250 068f0f489acaf988f6df6624962c0454 341 Pfam PF12706 Beta-lactamase superfamily domain 101 295 1.2E-45 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS06250 068f0f489acaf988f6df6624962c0454 341 Gene3D G3DSA:3.60.15.10 66 317 3.4E-77 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS06250 068f0f489acaf988f6df6624962c0454 341 SUPERFAMILY SSF56281 83 312 2.23E-39 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS26825 bde9c2c269d76d8216dc3fc671ce23d4 389 SUPERFAMILY SSF51556 56 348 1.76E-75 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS26825 bde9c2c269d76d8216dc3fc671ce23d4 389 SUPERFAMILY SSF51338 23 56 4.8E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS26825 bde9c2c269d76d8216dc3fc671ce23d4 389 SUPERFAMILY SSF51338 351 386 4.8E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS26825 bde9c2c269d76d8216dc3fc671ce23d4 389 Pfam PF01979 Amidohydrolase family 52 385 7.9E-33 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 SMD11_RS26825 bde9c2c269d76d8216dc3fc671ce23d4 389 Gene3D G3DSA:2.30.40.10 336 360 1.2E-5 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS26825 bde9c2c269d76d8216dc3fc671ce23d4 389 Gene3D G3DSA:2.30.40.10 361 388 3.4E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS26825 bde9c2c269d76d8216dc3fc671ce23d4 389 Gene3D G3DSA:2.30.40.10 3 57 3.4E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS26825 bde9c2c269d76d8216dc3fc671ce23d4 389 Gene3D G3DSA:3.20.20.140 58 335 2.0E-77 T 06-07-2017 SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 ProSitePatterns PS00622 LuxR-type HTH domain signature. 892 919 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 Pfam PF00196 Bacterial regulatory proteins, luxR family 877 930 2.4E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 SUPERFAMILY SSF48452 698 850 8.22E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 SUPERFAMILY SSF52540 3 170 2.27E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 Pfam PF13191 AAA ATPase domain 3 158 3.3E-16 T 06-07-2017 SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 SMART SM00421 875 932 1.2E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 Gene3D G3DSA:1.10.10.10 866 929 1.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 Gene3D G3DSA:1.25.40.10 403 476 6.3E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 Gene3D G3DSA:1.25.40.10 575 762 6.3E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 Gene3D G3DSA:1.25.40.10 763 858 4.4E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 SUPERFAMILY SSF48452 628 726 3.98E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 908 920 1.3E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 892 908 1.3E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 878 892 1.3E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 SUPERFAMILY SSF46894 870 931 1.46E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 Gene3D G3DSA:3.40.50.300 11 67 1.0E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16165 bd9868218b902bf1f1bdb185b202317b 941 Gene3D G3DSA:3.40.50.300 112 167 1.0E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29355 53c1fee4452e401d64ac6b295b216205 384 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 68 83 2.6E-14 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMD11_RS29355 53c1fee4452e401d64ac6b295b216205 384 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 114 134 2.6E-14 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMD11_RS29355 53c1fee4452e401d64ac6b295b216205 384 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 158 184 2.6E-14 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMD11_RS29355 53c1fee4452e401d64ac6b295b216205 384 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 196 218 2.6E-14 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMD11_RS29355 53c1fee4452e401d64ac6b295b216205 384 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 38 63 2.6E-14 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 SMD11_RS29355 53c1fee4452e401d64ac6b295b216205 384 SUPERFAMILY SSF50022 21 174 4.32E-41 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS29355 53c1fee4452e401d64ac6b295b216205 384 Gene3D G3DSA:3.90.380.10 167 243 1.2E-10 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 SMD11_RS29355 53c1fee4452e401d64ac6b295b216205 384 Gene3D G3DSA:2.102.10.10 51 166 2.1E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS29355 53c1fee4452e401d64ac6b295b216205 384 SUPERFAMILY SSF55961 183 383 4.16E-28 T 06-07-2017 SMD11_RS29355 53c1fee4452e401d64ac6b295b216205 384 Pfam PF00355 Rieske [2Fe-2S] domain 53 135 8.1E-17 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS29355 53c1fee4452e401d64ac6b295b216205 384 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 196 383 1.6E-26 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 SMD11_RS30035 6f28d984e143796589d38ef2596f88fb 261 Pfam PF08241 Methyltransferase domain 52 142 2.2E-18 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS30035 6f28d984e143796589d38ef2596f88fb 261 Gene3D G3DSA:3.40.50.150 35 246 7.0E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS30035 6f28d984e143796589d38ef2596f88fb 261 SUPERFAMILY SSF53335 20 240 1.05E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS30685 ba1db61be713094a884b986bffeeffcc 287 Gene3D G3DSA:3.40.190.10 171 256 4.0E-10 T 06-07-2017 SMD11_RS30685 ba1db61be713094a884b986bffeeffcc 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 3.1E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS30685 ba1db61be713094a884b986bffeeffcc 287 SUPERFAMILY SSF46785 4 88 1.33E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30685 ba1db61be713094a884b986bffeeffcc 287 Pfam PF03466 LysR substrate binding domain 88 284 1.2E-24 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS30685 ba1db61be713094a884b986bffeeffcc 287 Gene3D G3DSA:1.10.10.10 4 87 1.8E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30685 ba1db61be713094a884b986bffeeffcc 287 Gene3D G3DSA:3.40.190.10 91 170 4.5E-15 T 06-07-2017 SMD11_RS30685 ba1db61be713094a884b986bffeeffcc 287 SUPERFAMILY SSF53850 88 286 4.16E-23 T 06-07-2017 SMD11_RS30685 ba1db61be713094a884b986bffeeffcc 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 6.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS30685 ba1db61be713094a884b986bffeeffcc 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 6.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS30685 ba1db61be713094a884b986bffeeffcc 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 6.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS07845 bd347cad4519b74eb5bfea51f3611f74 251 Gene3D G3DSA:3.40.30.10 178 201 4.9E-5 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS07845 bd347cad4519b74eb5bfea51f3611f74 251 Gene3D G3DSA:3.40.30.10 20 103 4.9E-5 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS07845 bd347cad4519b74eb5bfea51f3611f74 251 Gene3D G3DSA:1.10.472.60 104 177 5.9E-9 T 06-07-2017 IPR023169 UPF0413, central domain SMD11_RS07845 bd347cad4519b74eb5bfea51f3611f74 251 Pfam PF01323 DSBA-like thioredoxin domain 24 201 2.9E-8 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMD11_RS07845 bd347cad4519b74eb5bfea51f3611f74 251 SUPERFAMILY SSF52833 24 201 3.84E-15 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS27460 667b4621aae24b6ca0db68bbaeb284c3 566 Gene3D G3DSA:3.90.660.10 83 156 2.2E-26 T 06-07-2017 SMD11_RS27460 667b4621aae24b6ca0db68bbaeb284c3 566 Gene3D G3DSA:3.90.660.10 368 470 2.2E-26 T 06-07-2017 SMD11_RS27460 667b4621aae24b6ca0db68bbaeb284c3 566 Gene3D G3DSA:3.40.50.720 50 82 2.3E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS27460 667b4621aae24b6ca0db68bbaeb284c3 566 Pfam PF01593 Flavin containing amine oxidoreductase 61 535 6.0E-45 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD11_RS27460 667b4621aae24b6ca0db68bbaeb284c3 566 SUPERFAMILY SSF54373 364 479 1.05E-27 T 06-07-2017 SMD11_RS27460 667b4621aae24b6ca0db68bbaeb284c3 566 SUPERFAMILY SSF51905 51 379 8.7E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS27460 667b4621aae24b6ca0db68bbaeb284c3 566 SUPERFAMILY SSF51905 501 541 8.7E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS27460 667b4621aae24b6ca0db68bbaeb284c3 566 Gene3D G3DSA:3.50.50.60 504 545 7.0E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS27460 667b4621aae24b6ca0db68bbaeb284c3 566 Gene3D G3DSA:3.50.50.60 306 364 7.0E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03305 2cbfa6a63064b4328def524034c35dd0 437 SUPERFAMILY SSF53901 22 270 3.27E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS03305 2cbfa6a63064b4328def524034c35dd0 437 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 24 260 1.7E-38 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS03305 2cbfa6a63064b4328def524034c35dd0 437 Gene3D G3DSA:3.40.47.10 23 279 1.6E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS03305 2cbfa6a63064b4328def524034c35dd0 437 SUPERFAMILY SSF53901 233 434 1.93E-41 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS03305 2cbfa6a63064b4328def524034c35dd0 437 SMART SM00825 Beta-ketoacyl synthase 26 437 0.0023 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS03305 2cbfa6a63064b4328def524034c35dd0 437 Gene3D G3DSA:3.40.47.10 297 435 1.2E-31 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS03305 2cbfa6a63064b4328def524034c35dd0 437 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 274 389 1.4E-19 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS12485 0c92bbea64672ad844c77ed9aa7f07a7 381 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 193 207 - T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMD11_RS12485 0c92bbea64672ad844c77ed9aa7f07a7 381 Gene3D G3DSA:3.40.640.10 6 249 1.3E-100 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS12485 0c92bbea64672ad844c77ed9aa7f07a7 381 Gene3D G3DSA:3.90.1150.10 250 380 5.1E-49 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS12485 0c92bbea64672ad844c77ed9aa7f07a7 381 SUPERFAMILY SSF53383 8 380 2.11E-121 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS12485 0c92bbea64672ad844c77ed9aa7f07a7 381 PIRSF PIRSF001434 1 381 6.8E-144 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMD11_RS12485 0c92bbea64672ad844c77ed9aa7f07a7 381 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 380 1.7E-148 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 SMD11_RS15075 6ccd9f08a90e9e31dfcca1dcb81e0a8c 341 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 188 208 6.4E-35 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS15075 6ccd9f08a90e9e31dfcca1dcb81e0a8c 341 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 48 66 6.4E-35 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS15075 6ccd9f08a90e9e31dfcca1dcb81e0a8c 341 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 133 152 6.4E-35 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS15075 6ccd9f08a90e9e31dfcca1dcb81e0a8c 341 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 68 91 6.4E-35 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS15075 6ccd9f08a90e9e31dfcca1dcb81e0a8c 341 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 298 324 6.4E-35 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS15075 6ccd9f08a90e9e31dfcca1dcb81e0a8c 341 Gene3D G3DSA:3.30.420.40 261 315 1.0E-20 T 06-07-2017 SMD11_RS15075 6ccd9f08a90e9e31dfcca1dcb81e0a8c 341 Gene3D G3DSA:3.30.420.40 161 187 1.0E-20 T 06-07-2017 SMD11_RS15075 6ccd9f08a90e9e31dfcca1dcb81e0a8c 341 Gene3D G3DSA:3.90.640.10 188 257 1.3E-10 T 06-07-2017 SMD11_RS15075 6ccd9f08a90e9e31dfcca1dcb81e0a8c 341 Pfam PF06723 MreB/Mbl protein 11 328 3.2E-99 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 SMD11_RS15075 6ccd9f08a90e9e31dfcca1dcb81e0a8c 341 Gene3D G3DSA:3.30.420.40 12 160 2.9E-20 T 06-07-2017 SMD11_RS15075 6ccd9f08a90e9e31dfcca1dcb81e0a8c 341 SUPERFAMILY SSF53067 11 149 5.67E-21 T 06-07-2017 SMD11_RS15075 6ccd9f08a90e9e31dfcca1dcb81e0a8c 341 SUPERFAMILY SSF53067 150 326 1.95E-30 T 06-07-2017 SMD11_RS24865 fb5062b0f156210ed2cf36dfa7966dde 986 Pfam PF11838 ERAP1-like C-terminal domain 664 976 6.4E-41 T 06-07-2017 IPR024571 ERAP1-like C-terminal domain SMD11_RS24865 fb5062b0f156210ed2cf36dfa7966dde 986 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 129 144 5.6E-20 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS24865 fb5062b0f156210ed2cf36dfa7966dde 986 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 309 321 5.6E-20 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS24865 fb5062b0f156210ed2cf36dfa7966dde 986 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 256 266 5.6E-20 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS24865 fb5062b0f156210ed2cf36dfa7966dde 986 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 175 190 5.6E-20 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS24865 fb5062b0f156210ed2cf36dfa7966dde 986 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 290 305 5.6E-20 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS24865 fb5062b0f156210ed2cf36dfa7966dde 986 SUPERFAMILY SSF55486 201 451 1.76E-70 T 06-07-2017 SMD11_RS24865 fb5062b0f156210ed2cf36dfa7966dde 986 SUPERFAMILY SSF63737 8 192 9.29E-33 T 06-07-2017 SMD11_RS24865 fb5062b0f156210ed2cf36dfa7966dde 986 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 4 460 1.0E-208 T 06-07-2017 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 SMD11_RS24865 fb5062b0f156210ed2cf36dfa7966dde 986 Gene3D G3DSA:1.10.390.10 303 453 1.3E-38 T 06-07-2017 SMD11_RS24865 fb5062b0f156210ed2cf36dfa7966dde 986 Pfam PF01433 Peptidase family M1 89 385 3.1E-59 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS17410 ae848a6297e4aab4c22be85f22d8836f 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 5.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17410 ae848a6297e4aab4c22be85f22d8836f 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 5.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17410 ae848a6297e4aab4c22be85f22d8836f 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 5.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17410 ae848a6297e4aab4c22be85f22d8836f 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17410 ae848a6297e4aab4c22be85f22d8836f 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 5.3E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17410 ae848a6297e4aab4c22be85f22d8836f 230 Pfam PF00106 short chain dehydrogenase 8 192 3.0E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17410 ae848a6297e4aab4c22be85f22d8836f 230 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS17410 ae848a6297e4aab4c22be85f22d8836f 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 2.1E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17410 ae848a6297e4aab4c22be85f22d8836f 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.1E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17410 ae848a6297e4aab4c22be85f22d8836f 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.1E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17410 ae848a6297e4aab4c22be85f22d8836f 230 Gene3D G3DSA:3.40.50.720 1 227 2.5E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17410 ae848a6297e4aab4c22be85f22d8836f 230 SUPERFAMILY SSF51735 1 225 7.01E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04885 7bfe61c9d337e7d947127990538bc8e8 378 SUPERFAMILY SSF55909 8 370 1.96E-95 T 06-07-2017 SMD11_RS04885 7bfe61c9d337e7d947127990538bc8e8 378 Pfam PF02274 Amidinotransferase 214 359 3.2E-7 T 06-07-2017 SMD11_RS04885 7bfe61c9d337e7d947127990538bc8e8 378 Gene3D G3DSA:3.75.10.10 7 369 1.1E-130 T 06-07-2017 SMD11_RS20925 3182b9188f16edd269d9b6575ca6df74 368 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 244 260 - T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SMD11_RS20925 3182b9188f16edd269d9b6575ca6df74 368 Gene3D G3DSA:3.30.160.20 227 305 1.2E-35 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain SMD11_RS20925 3182b9188f16edd269d9b6575ca6df74 368 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 364 38.21 T 06-07-2017 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 SMD11_RS20925 3182b9188f16edd269d9b6575ca6df74 368 SUPERFAMILY SSF75620 30 366 1.7E-121 T 06-07-2017 SMD11_RS20925 3182b9188f16edd269d9b6575ca6df74 368 Pfam PF00472 RF-1 domain 228 336 2.7E-38 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SMD11_RS20925 3182b9188f16edd269d9b6575ca6df74 368 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 363 1.2E-155 T 06-07-2017 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 SMD11_RS20925 3182b9188f16edd269d9b6575ca6df74 368 Gene3D G3DSA:1.20.58.410 4 115 1.6E-32 T 06-07-2017 SMD11_RS20925 3182b9188f16edd269d9b6575ca6df74 368 SMART SM00937 84 194 2.4E-42 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 SMD11_RS20925 3182b9188f16edd269d9b6575ca6df74 368 Pfam PF03462 PCRF domain 30 219 5.9E-55 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 SMD11_RS18290 a5a9bef3f9b31e2d2a4048d7eb977ffc 553 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 13 227 9.1E-34 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS18290 a5a9bef3f9b31e2d2a4048d7eb977ffc 553 Gene3D G3DSA:3.40.50.10090 277 399 5.3E-40 T 06-07-2017 SMD11_RS18290 a5a9bef3f9b31e2d2a4048d7eb977ffc 553 Gene3D G3DSA:3.40.50.10090 407 525 5.1E-34 T 06-07-2017 SMD11_RS18290 a5a9bef3f9b31e2d2a4048d7eb977ffc 553 SUPERFAMILY SSF53790 8 275 4.97E-42 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS18290 a5a9bef3f9b31e2d2a4048d7eb977ffc 553 SUPERFAMILY SSF69618 272 522 3.01E-65 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18290 a5a9bef3f9b31e2d2a4048d7eb977ffc 553 Gene3D G3DSA:3.40.1010.10 11 133 2.2E-29 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS18290 a5a9bef3f9b31e2d2a4048d7eb977ffc 553 Pfam PF02602 Uroporphyrinogen-III synthase HemD 286 516 1.6E-63 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18290 a5a9bef3f9b31e2d2a4048d7eb977ffc 553 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 17 31 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMD11_RS18290 a5a9bef3f9b31e2d2a4048d7eb977ffc 553 Gene3D G3DSA:3.30.950.10 136 276 5.6E-27 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS33365 7ba3b2af7f1bf064e7e492ee137e5271 301 SUPERFAMILY SSF53474 7 285 5.91E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS33365 7ba3b2af7f1bf064e7e492ee137e5271 301 Pfam PF00561 alpha/beta hydrolase fold 31 268 5.1E-23 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS33365 7ba3b2af7f1bf064e7e492ee137e5271 301 Gene3D G3DSA:3.40.50.1820 9 285 4.1E-63 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS33365 7ba3b2af7f1bf064e7e492ee137e5271 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 1.2E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS33365 7ba3b2af7f1bf064e7e492ee137e5271 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 1.2E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS33365 7ba3b2af7f1bf064e7e492ee137e5271 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 1.2E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS33365 7ba3b2af7f1bf064e7e492ee137e5271 301 PRINTS PR00412 Epoxide hydrolase signature 37 55 1.7E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 SMD11_RS33365 7ba3b2af7f1bf064e7e492ee137e5271 301 PRINTS PR00412 Epoxide hydrolase signature 260 282 1.7E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 SMD11_RS33365 7ba3b2af7f1bf064e7e492ee137e5271 301 PRINTS PR00412 Epoxide hydrolase signature 57 72 1.7E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 SMD11_RS22440 9ffb883eea4e64c715a7fca9ef5bf9ff 1328 Gene3D G3DSA:2.40.50.140 638 728 2.6E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS22440 9ffb883eea4e64c715a7fca9ef5bf9ff 1328 SUPERFAMILY SSF50249 645 728 7.5E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS22440 9ffb883eea4e64c715a7fca9ef5bf9ff 1328 Pfam PF10150 Ribonuclease E/G family 724 993 5.1E-108 T 06-07-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 SMD11_RS22440 9ffb883eea4e64c715a7fca9ef5bf9ff 1328 SMART SM00316 643 722 2.3E-5 T 06-07-2017 IPR022967 RNA-binding domain, S1 SMD11_RS22440 9ffb883eea4e64c715a7fca9ef5bf9ff 1328 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 620 1018 2.0E-153 T 06-07-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 SMD11_RS03515 2fc6233a073cfcdbe7dbd48779a5d3a1 140 PIRSF PIRSF004681 3 140 1.5E-27 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 SMD11_RS03515 2fc6233a073cfcdbe7dbd48779a5d3a1 140 Gene3D G3DSA:2.60.120.460 5 140 1.9E-32 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 SMD11_RS03515 2fc6233a073cfcdbe7dbd48779a5d3a1 140 SUPERFAMILY SSF111038 6 140 4.19E-32 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 SMD11_RS03515 2fc6233a073cfcdbe7dbd48779a5d3a1 140 Pfam PF01894 Uncharacterised protein family UPF0047 22 136 1.7E-23 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 SMD11_RS15610 710261a9157a4a0316eac4c8e72ea0bb 367 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 17 361 32.611 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD11_RS15610 710261a9157a4a0316eac4c8e72ea0bb 367 SMART SM00859 19 134 4.1E-33 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD11_RS15610 710261a9157a4a0316eac4c8e72ea0bb 367 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 347 1.1E-44 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS15610 710261a9157a4a0316eac4c8e72ea0bb 367 SUPERFAMILY SSF51735 19 170 1.56E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS15610 710261a9157a4a0316eac4c8e72ea0bb 367 Gene3D G3DSA:3.40.50.720 17 156 3.4E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS15610 710261a9157a4a0316eac4c8e72ea0bb 367 SUPERFAMILY SSF55347 143 348 1.79E-65 T 06-07-2017 SMD11_RS15610 710261a9157a4a0316eac4c8e72ea0bb 367 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 20 361 6.5E-110 T 06-07-2017 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD11_RS15610 710261a9157a4a0316eac4c8e72ea0bb 367 PIRSF PIRSF000148 17 365 2.0E-113 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD11_RS15610 710261a9157a4a0316eac4c8e72ea0bb 367 Gene3D G3DSA:3.30.360.10 157 343 3.0E-71 T 06-07-2017 SMD11_RS15610 710261a9157a4a0316eac4c8e72ea0bb 367 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 20 130 9.7E-28 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD11_RS19150 e9d54b0725c12bd08783ed9457aa5794 1107 SUPERFAMILY SSF52540 300 444 2.18E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19150 e9d54b0725c12bd08783ed9457aa5794 1107 Pfam PF05729 NACHT domain 309 472 9.0E-24 T 06-07-2017 SMD11_RS19150 e9d54b0725c12bd08783ed9457aa5794 1107 Pfam PF13365 Trypsin-like peptidase domain 17 166 1.7E-6 T 06-07-2017 SMD11_RS19150 e9d54b0725c12bd08783ed9457aa5794 1107 SUPERFAMILY SSF50494 13 177 8.07E-14 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS19150 e9d54b0725c12bd08783ed9457aa5794 1107 Gene3D G3DSA:3.40.50.300 300 334 1.0E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00230 dfed9c73dbf34397cbebb6213c2524b2 179 Gene3D G3DSA:3.90.1140.10 23 178 2.1E-12 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase SMD11_RS00230 dfed9c73dbf34397cbebb6213c2524b2 179 SUPERFAMILY SSF55144 26 178 1.41E-13 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase SMD11_RS00230 dfed9c73dbf34397cbebb6213c2524b2 179 Pfam PF13563 2'-5' RNA ligase superfamily 24 166 2.2E-22 T 06-07-2017 SMD11_RS27240 6052ac4372058643ccbc09727ed0528c 220 Pfam PF07884 Vitamin K epoxide reductase family 33 168 4.3E-27 T 06-07-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 SMD11_RS27240 6052ac4372058643ccbc09727ed0528c 220 SMART SM00756 27 172 7.1E-50 T 06-07-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 SMD11_RS01770 346fec38c6c80ef59d657f1e57715f46 288 Pfam PF06445 GyrI-like small molecule binding domain 126 283 1.7E-24 T 06-07-2017 IPR029442 GyrI-like small molecule binding domain SMD11_RS01770 346fec38c6c80ef59d657f1e57715f46 288 Gene3D G3DSA:1.10.10.60 56 113 5.2E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS01770 346fec38c6c80ef59d657f1e57715f46 288 SUPERFAMILY SSF55136 126 285 3.4E-22 T 06-07-2017 IPR011256 Regulatory factor, effector binding domain SMD11_RS01770 346fec38c6c80ef59d657f1e57715f46 288 SUPERFAMILY SSF46689 55 105 1.16E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS01770 346fec38c6c80ef59d657f1e57715f46 288 Pfam PF12833 Helix-turn-helix domain 25 103 1.9E-15 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS01770 346fec38c6c80ef59d657f1e57715f46 288 Gene3D G3DSA:3.20.80.10 114 284 1.4E-24 T 06-07-2017 IPR011256 Regulatory factor, effector binding domain SMD11_RS01770 346fec38c6c80ef59d657f1e57715f46 288 SUPERFAMILY SSF46689 3 53 9.86E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS01770 346fec38c6c80ef59d657f1e57715f46 288 SMART SM00871 126 284 1.7E-25 T 06-07-2017 IPR010499 Bacterial transcription activator, effector binding SMD11_RS01770 346fec38c6c80ef59d657f1e57715f46 288 Gene3D G3DSA:1.10.10.60 3 55 2.8E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS01770 346fec38c6c80ef59d657f1e57715f46 288 SMART SM00342 19 102 4.2E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS06510 dd6e3d6eedd48cea78f7b2e2f38b35d9 401 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 230 1.1E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS06510 dd6e3d6eedd48cea78f7b2e2f38b35d9 401 SUPERFAMILY SSF47203 245 397 9.5E-54 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS06510 dd6e3d6eedd48cea78f7b2e2f38b35d9 401 SUPERFAMILY SSF56645 9 253 4.58E-71 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS06510 dd6e3d6eedd48cea78f7b2e2f38b35d9 401 Gene3D G3DSA:1.10.540.10 9 123 2.3E-38 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS06510 dd6e3d6eedd48cea78f7b2e2f38b35d9 401 Gene3D G3DSA:2.40.110.10 125 231 3.9E-33 T 06-07-2017 SMD11_RS06510 dd6e3d6eedd48cea78f7b2e2f38b35d9 401 PIRSF PIRSF016578 6 396 9.4E-17 T 06-07-2017 SMD11_RS06510 dd6e3d6eedd48cea78f7b2e2f38b35d9 401 Gene3D G3DSA:1.20.140.10 232 398 1.1E-60 T 06-07-2017 SMD11_RS06510 dd6e3d6eedd48cea78f7b2e2f38b35d9 401 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 394 4.6E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS06510 dd6e3d6eedd48cea78f7b2e2f38b35d9 401 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 122 4.2E-32 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS05310 be355bc4a74502f271eb045fe9922580 388 SUPERFAMILY SSF51717 33 223 1.88E-10 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS05310 be355bc4a74502f271eb045fe9922580 388 Pfam PF04551 GcpE protein 26 365 8.5E-134 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD11_RS05310 be355bc4a74502f271eb045fe9922580 388 PIRSF PIRSF004640 15 376 2.6E-146 T 06-07-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD11_RS05310 be355bc4a74502f271eb045fe9922580 388 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 22 364 8.4E-130 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD11_RS05310 be355bc4a74502f271eb045fe9922580 388 SUPERFAMILY SSF56014 279 364 4.64E-11 T 06-07-2017 SMD11_RS05310 be355bc4a74502f271eb045fe9922580 388 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 20 371 33.96 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD11_RS28365 16f9e1db748f4fad075322d7678e5fce 340 SUPERFAMILY SSF89550 100 335 3.01E-47 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMD11_RS28365 16f9e1db748f4fad075322d7678e5fce 340 Pfam PF02811 PHP domain 102 187 7.9E-7 T 06-07-2017 IPR004013 PHP domain GO:0003824 SMD11_RS28365 16f9e1db748f4fad075322d7678e5fce 340 Gene3D G3DSA:3.20.20.140 100 337 1.8E-44 T 06-07-2017 SMD11_RS28365 16f9e1db748f4fad075322d7678e5fce 340 Pfam PF14716 Helix-hairpin-helix domain 5 69 4.7E-14 T 06-07-2017 IPR010996 DNA polymerase beta-like, N-terminal domain SMD11_RS28365 16f9e1db748f4fad075322d7678e5fce 340 SUPERFAMILY SSF47802 3 82 3.01E-10 T 06-07-2017 IPR010996 DNA polymerase beta-like, N-terminal domain SMD11_RS28365 16f9e1db748f4fad075322d7678e5fce 340 SMART SM00481 101 184 1.7E-15 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 SMD11_RS28365 16f9e1db748f4fad075322d7678e5fce 340 PIRSF PIRSF036978 1 340 2.0E-176 T 06-07-2017 IPR017078 Uncharacterised conserved protein UCP036978, histidinol phosphatase-related hydrolase, SCO0789 SMD11_RS28365 16f9e1db748f4fad075322d7678e5fce 340 Gene3D G3DSA:1.10.8.310 5 71 1.2E-7 T 06-07-2017 IPR027420 DNA polymerase beta, N-terminal domain SMD11_RS06910 32043a2905eeba87e6ebb4d66afa7773 260 SUPERFAMILY SSF46785 16 86 2.03E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06910 32043a2905eeba87e6ebb4d66afa7773 260 SMART SM00346 16 103 2.5E-22 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS06910 32043a2905eeba87e6ebb4d66afa7773 260 Pfam PF01614 Bacterial transcriptional regulator 131 253 2.0E-31 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal SMD11_RS06910 32043a2905eeba87e6ebb4d66afa7773 260 Gene3D G3DSA:3.30.450.40 90 255 1.3E-60 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS06910 32043a2905eeba87e6ebb4d66afa7773 260 SUPERFAMILY SSF55781 73 255 4.45E-51 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS06910 32043a2905eeba87e6ebb4d66afa7773 260 Gene3D G3DSA:1.10.10.10 14 88 5.3E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06910 32043a2905eeba87e6ebb4d66afa7773 260 Pfam PF09339 IclR helix-turn-helix domain 18 69 1.2E-17 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS04995 3a14e99dc81fa4c3e0580c8fb96d2d18 473 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 401 464 4.8E-13 T 06-07-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain SMD11_RS04995 3a14e99dc81fa4c3e0580c8fb96d2d18 473 Gene3D G3DSA:3.60.15.10 148 270 1.6E-43 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS04995 3a14e99dc81fa4c3e0580c8fb96d2d18 473 Gene3D G3DSA:3.60.15.10 8 113 1.6E-43 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS04995 3a14e99dc81fa4c3e0580c8fb96d2d18 473 SMART SM00849 26 256 2.0E-8 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS04995 3a14e99dc81fa4c3e0580c8fb96d2d18 473 SMART SM01027 261 388 5.0E-38 T 06-07-2017 IPR022712 Beta-Casp domain SMD11_RS04995 3a14e99dc81fa4c3e0580c8fb96d2d18 473 Pfam PF12706 Beta-lactamase superfamily domain 38 227 3.1E-9 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS04995 3a14e99dc81fa4c3e0580c8fb96d2d18 473 SUPERFAMILY SSF56281 16 470 4.59E-112 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS04995 3a14e99dc81fa4c3e0580c8fb96d2d18 473 Pfam PF10996 Beta-Casp domain 264 388 9.4E-22 T 06-07-2017 IPR022712 Beta-Casp domain SMD11_RS09740 94041918b6d8e1dd5b95ca37c2789f35 61 Pfam PF00830 Ribosomal L28 family 4 58 4.8E-23 T 06-07-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09740 94041918b6d8e1dd5b95ca37c2789f35 61 Gene3D G3DSA:4.10.1160.10 19 61 1.2E-22 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS09740 94041918b6d8e1dd5b95ca37c2789f35 61 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 61 15.982 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS09740 94041918b6d8e1dd5b95ca37c2789f35 61 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 56 3.4E-22 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS09740 94041918b6d8e1dd5b95ca37c2789f35 61 SUPERFAMILY SSF143800 2 59 3.92E-22 T 06-07-2017 SMD11_RS07905 8740ef60c33403564ccb23c8cd517a78 132 SUPERFAMILY SSF55298 8 132 1.41E-24 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD11_RS07905 8740ef60c33403564ccb23c8cd517a78 132 Gene3D G3DSA:3.30.1330.40 1 132 8.7E-27 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD11_RS07905 8740ef60c33403564ccb23c8cd517a78 132 Pfam PF01042 Endoribonuclease L-PSP 13 130 1.3E-15 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family SMD11_RS19195 fc40efb37081905b9eace8c7e8052063 375 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 10 324 5.9E-126 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS19195 fc40efb37081905b9eace8c7e8052063 375 ProSitePatterns PS01016 Glycoprotease family signature. 102 122 - T 06-07-2017 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 SMD11_RS19195 fc40efb37081905b9eace8c7e8052063 375 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 11 317 1.2E-97 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS19195 fc40efb37081905b9eace8c7e8052063 375 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 274 283 1.8E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS19195 fc40efb37081905b9eace8c7e8052063 375 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 137 149 1.8E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS19195 fc40efb37081905b9eace8c7e8052063 375 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 82 102 1.8E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS19195 fc40efb37081905b9eace8c7e8052063 375 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 103 122 1.8E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS19195 fc40efb37081905b9eace8c7e8052063 375 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 11 24 1.8E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS19195 fc40efb37081905b9eace8c7e8052063 375 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 161 182 1.8E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS19195 fc40efb37081905b9eace8c7e8052063 375 Gene3D G3DSA:3.30.420.40 9 166 4.9E-46 T 06-07-2017 SMD11_RS19195 fc40efb37081905b9eace8c7e8052063 375 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 8 343 61.115 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS19195 fc40efb37081905b9eace8c7e8052063 375 SUPERFAMILY SSF53067 9 319 3.7E-37 T 06-07-2017 SMD11_RS19195 fc40efb37081905b9eace8c7e8052063 375 Pfam PF00814 Glycoprotease family 30 317 6.3E-97 T 06-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SMD11_RS16305 a9f75938cffe5699862328eedcf8513f 496 Gene3D G3DSA:3.90.230.10 233 489 7.5E-69 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS16305 a9f75938cffe5699862328eedcf8513f 496 SMART SM01011 62 202 3.0E-35 T 06-07-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 SMD11_RS16305 a9f75938cffe5699862328eedcf8513f 496 Pfam PF00557 Metallopeptidase family M24 236 470 5.7E-50 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS16305 a9f75938cffe5699862328eedcf8513f 496 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 404 416 - T 06-07-2017 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site SMD11_RS16305 a9f75938cffe5699862328eedcf8513f 496 SUPERFAMILY SSF53092 63 228 1.62E-26 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal SMD11_RS16305 a9f75938cffe5699862328eedcf8513f 496 SUPERFAMILY SSF55920 229 491 1.96E-68 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS16305 a9f75938cffe5699862328eedcf8513f 496 Gene3D G3DSA:3.40.350.10 62 232 3.5E-38 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SMD11_RS16305 a9f75938cffe5699862328eedcf8513f 496 Pfam PF05195 Aminopeptidase P, N-terminal domain 68 187 2.5E-20 T 06-07-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 SMD11_RS16545 e63a92a02c1cdf4f5d8d37f9e0bea60a 562 SUPERFAMILY SSF55781 26 196 2.4E-32 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS16545 e63a92a02c1cdf4f5d8d37f9e0bea60a 562 SMART SM00387 465 562 5.8E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16545 e63a92a02c1cdf4f5d8d37f9e0bea60a 562 Pfam PF13185 GAF domain 40 179 1.4E-19 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS16545 e63a92a02c1cdf4f5d8d37f9e0bea60a 562 Pfam PF13185 GAF domain 209 343 1.4E-16 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS16545 e63a92a02c1cdf4f5d8d37f9e0bea60a 562 SUPERFAMILY SSF55781 210 356 8.29E-21 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS16545 e63a92a02c1cdf4f5d8d37f9e0bea60a 562 Pfam PF07730 Histidine kinase 361 422 1.7E-11 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS16545 e63a92a02c1cdf4f5d8d37f9e0bea60a 562 Gene3D G3DSA:3.30.565.10 468 524 3.2E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16545 e63a92a02c1cdf4f5d8d37f9e0bea60a 562 SUPERFAMILY SSF55874 470 561 4.45E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16545 e63a92a02c1cdf4f5d8d37f9e0bea60a 562 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 470 524 6.2E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16545 e63a92a02c1cdf4f5d8d37f9e0bea60a 562 SMART SM00065 210 353 7.2E-14 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS16545 e63a92a02c1cdf4f5d8d37f9e0bea60a 562 SMART SM00065 40 189 2.7E-14 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS16545 e63a92a02c1cdf4f5d8d37f9e0bea60a 562 Gene3D G3DSA:3.30.450.40 201 343 1.0E-19 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS16545 e63a92a02c1cdf4f5d8d37f9e0bea60a 562 Gene3D G3DSA:3.30.450.40 29 187 1.8E-30 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS25105 9e7a32ae1e6c80125fc0270de8f0ae4c 349 Gene3D G3DSA:3.40.50.10680 108 340 2.8E-45 T 06-07-2017 SMD11_RS25105 9e7a32ae1e6c80125fc0270de8f0ae4c 349 SUPERFAMILY SSF142338 31 335 2.22E-85 T 06-07-2017 SMD11_RS25105 9e7a32ae1e6c80125fc0270de8f0ae4c 349 Pfam PF01933 Uncharacterised protein family UPF0052 34 301 2.6E-73 T 06-07-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 SMD11_RS25105 9e7a32ae1e6c80125fc0270de8f0ae4c 349 Hamap MF_00973 Gluconeogenesis factor. 30 341 33.028 T 06-07-2017 IPR010119 Gluconeogenesis factor SMD11_RS25105 9e7a32ae1e6c80125fc0270de8f0ae4c 349 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 34 300 1.3E-85 T 06-07-2017 IPR010119 Gluconeogenesis factor SMD11_RS23995 72797b3a4ceddb4c46c4bcdaff744b57 451 Gene3D G3DSA:1.25.40.10 213 410 7.3E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS23995 72797b3a4ceddb4c46c4bcdaff744b57 451 SUPERFAMILY SSF48452 210 323 3.07E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS23995 72797b3a4ceddb4c46c4bcdaff744b57 451 SUPERFAMILY SSF48452 379 410 3.07E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS30025 e2762d63e1ba5b595c5fd1224d3b7a01 306 Pfam PF00753 Metallo-beta-lactamase superfamily 110 237 8.0E-8 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS30025 e2762d63e1ba5b595c5fd1224d3b7a01 306 Gene3D G3DSA:3.60.15.10 89 286 7.8E-52 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS30025 e2762d63e1ba5b595c5fd1224d3b7a01 306 SUPERFAMILY SSF56281 90 281 9.17E-37 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS30025 e2762d63e1ba5b595c5fd1224d3b7a01 306 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 23 76 4.1E-6 T 06-07-2017 SMD11_RS30025 e2762d63e1ba5b595c5fd1224d3b7a01 306 SMART SM00849 109 269 6.5E-16 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS25315 0390f4cf420ec346de604e1921abd72e 422 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 275 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS25315 0390f4cf420ec346de604e1921abd72e 422 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 8 421 6.3E-140 T 06-07-2017 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 SMD11_RS25315 0390f4cf420ec346de604e1921abd72e 422 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 10 419 1.4E-200 T 06-07-2017 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 SMD11_RS25315 0390f4cf420ec346de604e1921abd72e 422 SUPERFAMILY SSF53383 15 419 1.69E-108 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS25315 0390f4cf420ec346de604e1921abd72e 422 Pfam PF00202 Aminotransferase class-III 27 417 1.1E-73 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS25315 0390f4cf420ec346de604e1921abd72e 422 Gene3D G3DSA:3.40.640.10 62 318 1.5E-61 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS25315 0390f4cf420ec346de604e1921abd72e 422 Gene3D G3DSA:3.90.1150.10 19 61 3.0E-31 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS25315 0390f4cf420ec346de604e1921abd72e 422 Gene3D G3DSA:3.90.1150.10 324 420 3.0E-31 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS14775 522be7b9c4bbd2ed4b5d42db6b72910f 235 Pfam PF00072 Response regulator receiver domain 6 115 7.4E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS14775 522be7b9c4bbd2ed4b5d42db6b72910f 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 233 2.2E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS14775 522be7b9c4bbd2ed4b5d42db6b72910f 235 Gene3D G3DSA:1.10.10.10 142 234 8.9E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14775 522be7b9c4bbd2ed4b5d42db6b72910f 235 SUPERFAMILY SSF46894 139 233 7.09E-28 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS14775 522be7b9c4bbd2ed4b5d42db6b72910f 235 Gene3D G3DSA:3.40.50.2300 4 120 6.3E-39 T 06-07-2017 SMD11_RS14775 522be7b9c4bbd2ed4b5d42db6b72910f 235 SMART SM00448 4 114 1.3E-40 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS14775 522be7b9c4bbd2ed4b5d42db6b72910f 235 SUPERFAMILY SSF52172 3 123 8.11E-40 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS14775 522be7b9c4bbd2ed4b5d42db6b72910f 235 SMART SM00862 162 233 1.0E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS10050 20454c20c0c4c7dca963189b20e8da1b 275 SUPERFAMILY SSF89392 30 245 6.67E-9 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX SMD11_RS34425 b6636aedf32322793c3fa3fb79620536 198 Gene3D G3DSA:3.40.50.620 2 134 1.8E-37 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS34425 b6636aedf32322793c3fa3fb79620536 198 Pfam PF02698 DUF218 domain 21 126 1.4E-18 T 06-07-2017 IPR003848 Domain of unknown function DUF218 SMD11_RS17265 2bcc5cbb60d3d58201fdb997ccec8dbf 434 SUPERFAMILY SSF103473 12 420 3.92E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS17265 2bcc5cbb60d3d58201fdb997ccec8dbf 434 Gene3D G3DSA:1.20.1250.20 222 420 9.6E-15 T 06-07-2017 SMD11_RS17265 2bcc5cbb60d3d58201fdb997ccec8dbf 434 Gene3D G3DSA:1.20.1250.20 25 204 1.9E-26 T 06-07-2017 SMD11_RS17265 2bcc5cbb60d3d58201fdb997ccec8dbf 434 Pfam PF07690 Major Facilitator Superfamily 29 373 4.1E-32 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS25935 95e46f04454390ae9946931deb6376c4 103 Pfam PF05800 Gas vesicle synthesis protein GvpO 12 101 1.8E-30 T 06-07-2017 IPR008634 Gas vesicle protein GvpO GO:0031412 SMD11_RS25935 95e46f04454390ae9946931deb6376c4 103 PIRSF PIRSF028743 1 103 6.1E-33 T 06-07-2017 IPR008634 Gas vesicle protein GvpO GO:0031412 SMD11_RS12605 840803674293800b6ce549b65bbd0618 201 Pfam PF00484 Carbonic anhydrase 34 186 4.5E-42 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS12605 840803674293800b6ce549b65bbd0618 201 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 39 46 - T 06-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS12605 840803674293800b6ce549b65bbd0618 201 SUPERFAMILY SSF53056 1 190 3.14E-52 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS12605 840803674293800b6ce549b65bbd0618 201 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 83 103 - T 06-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS12605 840803674293800b6ce549b65bbd0618 201 Gene3D G3DSA:3.40.1050.10 1 186 9.3E-58 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS12605 840803674293800b6ce549b65bbd0618 201 SMART SM00947 27 190 9.2E-58 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1405 1632 2.3E-6 T 06-07-2017 SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 SUPERFAMILY SSF51735 1403 1446 6.67E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 SUPERFAMILY SSF51735 1491 1669 6.67E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 SUPERFAMILY SSF53901 809 925 4.9E-28 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 SUPERFAMILY SSF53901 956 1061 4.9E-28 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 SUPERFAMILY SSF51735 5 251 4.69E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 Gene3D G3DSA:3.40.47.10 633 790 3.5E-41 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 741 820 1.6E-10 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 1.0E-58 T 06-07-2017 SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 Pfam PF08659 KR domain 1406 1630 6.6E-18 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 857 1017 3.7E-19 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 341 618 1.3E-30 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 SMART SM00825 Beta-ketoacyl synthase 342 792 4.9E-37 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 Pfam PF14765 Polyketide synthase dehydratase 1716 2003 1.7E-15 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 626 737 8.8E-26 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 SUPERFAMILY SSF53901 585 790 8.83E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 Gene3D G3DSA:3.40.50.720 3 251 3.7E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 SUPERFAMILY SSF53901 340 457 1.24E-34 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 SUPERFAMILY SSF53901 486 625 1.24E-34 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 Gene3D G3DSA:3.40.50.720 1486 1635 4.6E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 Gene3D G3DSA:3.40.50.720 1404 1438 4.6E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.7E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.7E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.7E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.7E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.7E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.7E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 Gene3D G3DSA:3.40.47.10 813 1068 1.2E-27 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20345 7be20c3416b1fdf4ae6d223312e5b50d 2030 Gene3D G3DSA:3.40.47.10 342 630 5.9E-40 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29680 212d251b0b6c951810210a4cad8f8957 430 Pfam PF00120 Glutamine synthetase, catalytic domain 97 412 7.9E-75 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS29680 212d251b0b6c951810210a4cad8f8957 430 SMART SM01230 95 347 9.3E-74 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS29680 212d251b0b6c951810210a4cad8f8957 430 Gene3D G3DSA:3.30.590.10 98 412 6.3E-89 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SMD11_RS29680 212d251b0b6c951810210a4cad8f8957 430 SUPERFAMILY SSF54368 4 94 7.98E-5 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS29680 212d251b0b6c951810210a4cad8f8957 430 SUPERFAMILY SSF55931 97 413 1.57E-83 T 06-07-2017 SMD11_RS16740 c70b1367360d7a477bd5529d872fedac 241 Gene3D G3DSA:3.40.50.1820 3 233 2.5E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS16740 c70b1367360d7a477bd5529d872fedac 241 Pfam PF01738 Dienelactone hydrolase family 20 235 1.4E-32 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 SMD11_RS16740 c70b1367360d7a477bd5529d872fedac 241 SUPERFAMILY SSF53474 5 234 2.88E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30110 099920cddf6c8861f521928a1d466dac 236 SUPERFAMILY SSF52172 6 140 3.56E-32 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS30110 099920cddf6c8861f521928a1d466dac 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 201 7.8E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS30110 099920cddf6c8861f521928a1d466dac 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 185 7.8E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS30110 099920cddf6c8861f521928a1d466dac 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 201 213 7.8E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS30110 099920cddf6c8861f521928a1d466dac 236 Gene3D G3DSA:3.40.50.2300 2 129 3.5E-36 T 06-07-2017 SMD11_RS30110 099920cddf6c8861f521928a1d466dac 236 SMART SM00421 168 225 7.0E-27 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS30110 099920cddf6c8861f521928a1d466dac 236 SUPERFAMILY SSF46894 163 231 1.5E-22 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS30110 099920cddf6c8861f521928a1d466dac 236 Pfam PF00072 Response regulator receiver domain 8 122 4.9E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS30110 099920cddf6c8861f521928a1d466dac 236 SMART SM00448 6 121 1.2E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS30110 099920cddf6c8861f521928a1d466dac 236 ProSitePatterns PS00622 LuxR-type HTH domain signature. 185 212 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS30110 099920cddf6c8861f521928a1d466dac 236 Gene3D G3DSA:1.10.10.10 130 232 3.2E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30110 099920cddf6c8861f521928a1d466dac 236 Pfam PF00196 Bacterial regulatory proteins, luxR family 169 225 9.9E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS09440 dd514d78da8306beb1357898b8af421f 209 SUPERFAMILY SSF46689 3 73 6.48E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS09440 dd514d78da8306beb1357898b8af421f 209 Gene3D G3DSA:1.10.10.60 2 48 1.0E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS09440 dd514d78da8306beb1357898b8af421f 209 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 50 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD11_RS09440 dd514d78da8306beb1357898b8af421f 209 Gene3D G3DSA:1.10.357.10 49 204 4.9E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS09440 dd514d78da8306beb1357898b8af421f 209 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 146 199 6.5E-7 T 06-07-2017 SMD11_RS09440 dd514d78da8306beb1357898b8af421f 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 53 9.9E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS09440 dd514d78da8306beb1357898b8af421f 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 1.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS09440 dd514d78da8306beb1357898b8af421f 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 1.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS10515 fc88ad226e7573803bfc5c7fdbe36383 260 Gene3D G3DSA:3.40.50.300 21 238 8.8E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10515 fc88ad226e7573803bfc5c7fdbe36383 260 SMART SM00382 47 233 4.8E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS10515 fc88ad226e7573803bfc5c7fdbe36383 260 SUPERFAMILY SSF52540 21 237 9.29E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10515 fc88ad226e7573803bfc5c7fdbe36383 260 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS10515 fc88ad226e7573803bfc5c7fdbe36383 260 Pfam PF00005 ABC transporter 38 184 2.1E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS32195 3abf23d86306d46bc091226a210301e1 125 Pfam PF03995 Peptidase inhibitor family I36 32 106 1.3E-20 T 06-07-2017 SMD11_RS07575 116b612f86ddb570a5873055ad4f0a8d 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 292 3.0E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS07575 116b612f86ddb570a5873055ad4f0a8d 305 SUPERFAMILY SSF161098 51 290 2.22E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS07575 116b612f86ddb570a5873055ad4f0a8d 305 Gene3D G3DSA:1.10.3720.10 57 301 4.3E-62 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 Gene3D G3DSA:3.30.450.40 536 694 1.7E-22 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SUPERFAMILY SSF55781 524 694 1.18E-29 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 Gene3D G3DSA:3.40.50.2300 1210 1337 6.3E-42 T 06-07-2017 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SUPERFAMILY SSF58104 413 537 2.09E-11 T 06-07-2017 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SMART SM00065 561 710 2.5E-12 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 Pfam PF00072 Response regulator receiver domain 1220 1333 1.1E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 Pfam PF00512 His Kinase A (phospho-acceptor) domain 782 849 3.3E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SMART SM00304 485 537 1.6E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SMART SM00304 209 261 2.1E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SMART SM00304 301 353 2.4E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SMART SM00304 117 169 2.2E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SMART SM00304 393 445 1.8E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SMART SM00304 25 77 0.57 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 897 1017 2.3E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SUPERFAMILY SSF55874 838 1021 1.44E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 Pfam PF00672 HAMP domain 114 165 3.2E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 Pfam PF00672 HAMP domain 206 257 3.4E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 Pfam PF00672 HAMP domain 298 349 7.1E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 Pfam PF00672 HAMP domain 483 534 2.0E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SUPERFAMILY SSF58104 45 318 2.41E-15 T 06-07-2017 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SUPERFAMILY SSF52172 1094 1166 8.64E-7 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SMART SM00388 781 849 2.3E-21 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SUPERFAMILY SSF47384 766 851 1.88E-20 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SMART SM00387 896 1019 5.8E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 Gene3D G3DSA:3.30.565.10 850 1023 6.9E-45 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 Pfam PF13185 GAF domain 560 694 3.2E-19 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1003 1016 1.4E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 979 997 1.4E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 944 958 1.4E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SUPERFAMILY SSF52172 1217 1337 2.13E-39 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SMART SM00448 1218 1332 3.5E-40 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 SUPERFAMILY SSF58104 321 410 6.8E-5 T 06-07-2017 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 Gene3D G3DSA:3.40.50.2300 1091 1164 5.6E-7 T 06-07-2017 SMD11_RS32280 ff6c6f326934f29d096aafd12e663799 1338 Gene3D G3DSA:1.10.287.130 774 845 5.5E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS06485 4372b5fae2024f1116a2092beafdf7e3 318 Gene3D G3DSA:1.10.357.10 126 266 5.4E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS06485 4372b5fae2024f1116a2092beafdf7e3 318 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 86 99 2.0E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS06485 4372b5fae2024f1116a2092beafdf7e3 318 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 107 130 2.0E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS06485 4372b5fae2024f1116a2092beafdf7e3 318 SUPERFAMILY SSF46689 75 130 3.97E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS06485 4372b5fae2024f1116a2092beafdf7e3 318 Gene3D G3DSA:1.10.10.60 82 125 1.4E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS06485 4372b5fae2024f1116a2092beafdf7e3 318 Pfam PF00440 Bacterial regulatory proteins, tetR family 88 127 3.6E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS06485 4372b5fae2024f1116a2092beafdf7e3 318 ProSitePatterns PS01081 TetR-type HTH domain signature. 98 129 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD11_RS20570 66a2c7ccb9367590c8ca484b4ba51d96 418 Pfam PF00672 HAMP domain 130 197 5.9E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS20570 66a2c7ccb9367590c8ca484b4ba51d96 418 Gene3D G3DSA:3.30.565.10 271 395 3.7E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS20570 66a2c7ccb9367590c8ca484b4ba51d96 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 390 3.1E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS20570 66a2c7ccb9367590c8ca484b4ba51d96 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 3.1E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS20570 66a2c7ccb9367590c8ca484b4ba51d96 418 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 263 3.7E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS20570 66a2c7ccb9367590c8ca484b4ba51d96 418 Gene3D G3DSA:1.10.287.130 193 263 1.4E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS20570 66a2c7ccb9367590c8ca484b4ba51d96 418 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 394 5.2E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS20570 66a2c7ccb9367590c8ca484b4ba51d96 418 SUPERFAMILY SSF55874 270 396 1.27E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS20570 66a2c7ccb9367590c8ca484b4ba51d96 418 SMART SM00387 309 410 1.4E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS20570 66a2c7ccb9367590c8ca484b4ba51d96 418 SUPERFAMILY SSF47384 186 263 1.51E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS20570 66a2c7ccb9367590c8ca484b4ba51d96 418 SMART SM00388 202 267 1.4E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS19035 908276c60323581a6097cad13e810c2c 284 Gene3D G3DSA:3.30.70.660 121 257 5.4E-37 T 06-07-2017 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS19035 908276c60323581a6097cad13e810c2c 284 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 12 253 1.2E-47 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS19035 908276c60323581a6097cad13e810c2c 284 PIRSF PIRSF001430 10 276 7.0E-73 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS19035 908276c60323581a6097cad13e810c2c 284 Pfam PF01416 tRNA pseudouridine synthase 158 260 2.9E-23 T 06-07-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS19035 908276c60323581a6097cad13e810c2c 284 Pfam PF01416 tRNA pseudouridine synthase 18 117 4.6E-5 T 06-07-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS19035 908276c60323581a6097cad13e810c2c 284 Gene3D G3DSA:3.30.70.580 10 119 1.5E-32 T 06-07-2017 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS19035 908276c60323581a6097cad13e810c2c 284 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 10 259 30.182 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS19035 908276c60323581a6097cad13e810c2c 284 SUPERFAMILY SSF55120 9 265 1.24E-70 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS31105 1bf88303ddaeff7b48ffe8ace0db1931 368 SMART SM00331 143 366 3.7E-41 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS31105 1bf88303ddaeff7b48ffe8ace0db1931 368 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 171 366 2.5E-40 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS31105 1bf88303ddaeff7b48ffe8ace0db1931 368 SUPERFAMILY SSF81606 158 363 6.54E-8 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS19990 5fa1eb414aeee4ce922a646142934e11 190 SUPERFAMILY SSF48498 75 186 2.41E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS19990 5fa1eb414aeee4ce922a646142934e11 190 Gene3D G3DSA:1.10.10.60 2 55 1.2E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS19990 5fa1eb414aeee4ce922a646142934e11 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 58 1.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS19990 5fa1eb414aeee4ce922a646142934e11 190 SUPERFAMILY SSF46689 2 64 4.17E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS19990 5fa1eb414aeee4ce922a646142934e11 190 Gene3D G3DSA:1.10.357.10 56 187 1.4E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS19990 5fa1eb414aeee4ce922a646142934e11 190 Pfam PF16859 Bacterial transcriptional repressor C-terminal 72 183 1.5E-28 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS14075 1eafa7e400ed0b5881465db926211b98 335 Pfam PF00107 Zinc-binding dehydrogenase 155 250 4.0E-18 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS14075 1eafa7e400ed0b5881465db926211b98 335 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 93 1.1E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS14075 1eafa7e400ed0b5881465db926211b98 335 Gene3D G3DSA:3.90.180.10 1 150 1.6E-27 T 06-07-2017 IPR011032 GroES-like SMD11_RS14075 1eafa7e400ed0b5881465db926211b98 335 SMART SM00829 10 333 2.9E-10 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS14075 1eafa7e400ed0b5881465db926211b98 335 SUPERFAMILY SSF50129 1 121 6.39E-27 T 06-07-2017 IPR011032 GroES-like SMD11_RS14075 1eafa7e400ed0b5881465db926211b98 335 SUPERFAMILY SSF50129 305 333 6.39E-27 T 06-07-2017 IPR011032 GroES-like SMD11_RS14075 1eafa7e400ed0b5881465db926211b98 335 SUPERFAMILY SSF51735 138 257 4.94E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS14075 1eafa7e400ed0b5881465db926211b98 335 Gene3D G3DSA:3.40.50.720 151 302 5.5E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS02750 d89044a2681f383c137b08525e4bfbda 444 SUPERFAMILY SSF103473 8 393 1.31E-33 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS02750 d89044a2681f383c137b08525e4bfbda 444 Gene3D G3DSA:1.20.1250.20 3 200 4.9E-14 T 06-07-2017 SMD11_RS02750 d89044a2681f383c137b08525e4bfbda 444 Pfam PF07690 Major Facilitator Superfamily 13 345 1.5E-23 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS02750 d89044a2681f383c137b08525e4bfbda 444 Gene3D G3DSA:1.20.1250.20 219 393 9.7E-5 T 06-07-2017 SMD11_RS15730 6bc2fb2c1d62058b8d3da223daf87b1c 404 SUPERFAMILY SSF46458 37 160 5.49E-21 T 06-07-2017 IPR009050 Globin-like SMD11_RS15730 6bc2fb2c1d62058b8d3da223daf87b1c 404 Pfam PF00970 Oxidoreductase FAD-binding domain 175 266 5.3E-10 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SMD11_RS15730 6bc2fb2c1d62058b8d3da223daf87b1c 404 PRINTS PR00410 Phenol hydroxylase reductase family signature 368 376 1.1E-5 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD11_RS15730 6bc2fb2c1d62058b8d3da223daf87b1c 404 PRINTS PR00410 Phenol hydroxylase reductase family signature 199 211 1.1E-5 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD11_RS15730 6bc2fb2c1d62058b8d3da223daf87b1c 404 PRINTS PR00410 Phenol hydroxylase reductase family signature 280 299 1.1E-5 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD11_RS15730 6bc2fb2c1d62058b8d3da223daf87b1c 404 Gene3D G3DSA:2.40.30.10 172 267 8.7E-22 T 06-07-2017 SMD11_RS15730 6bc2fb2c1d62058b8d3da223daf87b1c 404 Gene3D G3DSA:1.10.490.10 50 164 3.8E-24 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 SMD11_RS15730 6bc2fb2c1d62058b8d3da223daf87b1c 404 SUPERFAMILY SSF52343 275 398 1.44E-18 T 06-07-2017 SMD11_RS15730 6bc2fb2c1d62058b8d3da223daf87b1c 404 SUPERFAMILY SSF63380 172 267 6.27E-19 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD11_RS15730 6bc2fb2c1d62058b8d3da223daf87b1c 404 Pfam PF00042 Globin 53 127 3.7E-5 T 06-07-2017 IPR000971 Globin GO:0019825|GO:0020037 SMD11_RS15730 6bc2fb2c1d62058b8d3da223daf87b1c 404 Gene3D G3DSA:3.40.50.80 275 398 2.6E-18 T 06-07-2017 SMD11_RS28890 f80bb825225aaeaf7cb0434784e7c566 412 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 115 1.3E-13 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS28890 f80bb825225aaeaf7cb0434784e7c566 412 Gene3D G3DSA:2.40.110.10 125 222 6.8E-35 T 06-07-2017 SMD11_RS28890 f80bb825225aaeaf7cb0434784e7c566 412 SUPERFAMILY SSF47203 261 408 4.35E-53 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS28890 f80bb825225aaeaf7cb0434784e7c566 412 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 223 1.2E-23 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS28890 f80bb825225aaeaf7cb0434784e7c566 412 Gene3D G3DSA:1.20.140.10 223 408 8.6E-64 T 06-07-2017 SMD11_RS28890 f80bb825225aaeaf7cb0434784e7c566 412 Gene3D G3DSA:1.10.540.10 4 115 1.2E-22 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS28890 f80bb825225aaeaf7cb0434784e7c566 412 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 262 406 1.8E-51 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS28890 f80bb825225aaeaf7cb0434784e7c566 412 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 365 384 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD11_RS28890 f80bb825225aaeaf7cb0434784e7c566 412 SUPERFAMILY SSF56645 5 235 2.62E-56 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS11650 b482fa4aee60ee76b7195348c0a9ce53 257 Pfam PF12138 Spherulation-specific family 4 57 250 5.3E-16 T 06-07-2017 IPR021986 Spherulation-specific family 4 SMD11_RS14100 5d2f150405c299759eaf0ed6297ee1c9 378 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS14100 5d2f150405c299759eaf0ed6297ee1c9 378 Pfam PF03459 TOBE domain 307 367 8.4E-8 T 06-07-2017 IPR005116 Transport-associated OB, type 1 SMD11_RS14100 5d2f150405c299759eaf0ed6297ee1c9 378 Gene3D G3DSA:2.40.50.140 285 359 6.7E-10 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS14100 5d2f150405c299759eaf0ed6297ee1c9 378 SMART SM00382 30 213 1.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS14100 5d2f150405c299759eaf0ed6297ee1c9 378 SUPERFAMILY SSF50331 238 376 2.83E-20 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal SMD11_RS14100 5d2f150405c299759eaf0ed6297ee1c9 378 Gene3D G3DSA:2.40.50.100 362 376 9.4E-7 T 06-07-2017 SMD11_RS14100 5d2f150405c299759eaf0ed6297ee1c9 378 Gene3D G3DSA:2.40.50.100 241 284 9.4E-7 T 06-07-2017 SMD11_RS14100 5d2f150405c299759eaf0ed6297ee1c9 378 Pfam PF00005 ABC transporter 22 163 1.2E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS14100 5d2f150405c299759eaf0ed6297ee1c9 378 SUPERFAMILY SSF52540 7 245 1.06E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14100 5d2f150405c299759eaf0ed6297ee1c9 378 Gene3D G3DSA:3.40.50.300 12 236 2.8E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13890 7d310d7f2ddf2f63f8e99b2d86799c8d 309 SUPERFAMILY SSF53697 122 297 5.38E-39 T 06-07-2017 SMD11_RS13890 7d310d7f2ddf2f63f8e99b2d86799c8d 309 Gene3D G3DSA:3.40.50.10490 122 291 1.7E-39 T 06-07-2017 SMD11_RS13890 7d310d7f2ddf2f63f8e99b2d86799c8d 309 Gene3D G3DSA:1.10.10.10 27 100 9.2E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13890 7d310d7f2ddf2f63f8e99b2d86799c8d 309 Pfam PF01380 SIS domain 153 282 1.2E-22 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 SMD11_RS13890 7d310d7f2ddf2f63f8e99b2d86799c8d 309 Pfam PF01418 Helix-turn-helix domain, rpiR family 27 96 2.5E-12 T 06-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SMD11_RS13890 7d310d7f2ddf2f63f8e99b2d86799c8d 309 SUPERFAMILY SSF46689 28 99 9.68E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS33300 16b22d84071075c4f2e0c206ac2f6c07 328 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 217 3.7E-46 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 SMD11_RS33300 16b22d84071075c4f2e0c206ac2f6c07 328 SUPERFAMILY SSF56176 2 217 1.8E-52 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS33300 16b22d84071075c4f2e0c206ac2f6c07 328 Gene3D G3DSA:3.30.43.10 2 49 1.3E-16 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS33300 16b22d84071075c4f2e0c206ac2f6c07 328 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 225 319 3.9E-17 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMD11_RS33300 16b22d84071075c4f2e0c206ac2f6c07 328 SMART SM01092 224 322 1.2E-26 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMD11_RS33300 16b22d84071075c4f2e0c206ac2f6c07 328 Gene3D G3DSA:3.30.390.50 222 326 2.4E-30 T 06-07-2017 SMD11_RS33300 16b22d84071075c4f2e0c206ac2f6c07 328 Gene3D G3DSA:3.30.465.10 55 111 1.2E-30 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS33300 16b22d84071075c4f2e0c206ac2f6c07 328 Gene3D G3DSA:3.30.465.10 155 217 1.2E-30 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS33300 16b22d84071075c4f2e0c206ac2f6c07 328 SUPERFAMILY SSF55447 223 322 2.49E-24 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMD11_RS14320 b7b78025f40dd3d2e2f6c1bea1f683f8 285 Pfam PF13460 NAD(P)H-binding 6 179 4.5E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS14320 b7b78025f40dd3d2e2f6c1bea1f683f8 285 SUPERFAMILY SSF51735 2 277 1.49E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS14320 b7b78025f40dd3d2e2f6c1bea1f683f8 285 Gene3D G3DSA:3.40.50.720 2 215 1.2E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS21755 0c3426df7c04d3b89410e5683e3c4f8f 295 Gene3D G3DSA:3.10.129.10 125 289 3.1E-51 T 06-07-2017 IPR029069 HotDog domain SMD11_RS21755 0c3426df7c04d3b89410e5683e3c4f8f 295 SUPERFAMILY SSF54637 116 290 1.82E-46 T 06-07-2017 IPR029069 HotDog domain SMD11_RS21755 0c3426df7c04d3b89410e5683e3c4f8f 295 Gene3D G3DSA:3.10.129.10 5 115 1.4E-49 T 06-07-2017 IPR029069 HotDog domain SMD11_RS21755 0c3426df7c04d3b89410e5683e3c4f8f 295 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 12 287 5.8E-88 T 06-07-2017 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-75105 SMD11_RS21755 0c3426df7c04d3b89410e5683e3c4f8f 295 SUPERFAMILY SSF54637 5 114 8.38E-44 T 06-07-2017 IPR029069 HotDog domain SMD11_RS21755 0c3426df7c04d3b89410e5683e3c4f8f 295 Pfam PF13622 Thioesterase-like superfamily 32 286 1.8E-60 T 06-07-2017 SMD11_RS23840 11ffbf8cda3fb113edd26aa5d2238426 586 Pfam PF02540 NAD synthase 311 558 4.6E-67 T 06-07-2017 IPR022310 NAD/GMP synthase SMD11_RS23840 11ffbf8cda3fb113edd26aa5d2238426 586 Pfam PF00795 Carbon-nitrogen hydrolase 8 262 1.4E-19 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS23840 11ffbf8cda3fb113edd26aa5d2238426 586 TIGRFAM TIGR00552 nadE: NAD+ synthetase 309 561 7.5E-55 T 06-07-2017 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 SMD11_RS23840 11ffbf8cda3fb113edd26aa5d2238426 586 SUPERFAMILY SSF56317 6 262 2.75E-52 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS23840 11ffbf8cda3fb113edd26aa5d2238426 586 Gene3D G3DSA:3.60.110.10 6 261 2.0E-51 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS23840 11ffbf8cda3fb113edd26aa5d2238426 586 SUPERFAMILY SSF52402 299 566 1.09E-74 T 06-07-2017 SMD11_RS23840 11ffbf8cda3fb113edd26aa5d2238426 586 PIRSF PIRSF006630 4 586 1.4E-207 T 06-07-2017 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 SMD11_RS23840 11ffbf8cda3fb113edd26aa5d2238426 586 Gene3D G3DSA:3.40.50.620 299 566 1.2E-72 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS21325 de4ee8b0baacdf2f74dd19d8e3a06c99 266 Pfam PF06182 ABC-2 family transporter protein 40 252 5.2E-17 T 06-07-2017 IPR010390 Protein of unknown function DUF990 SMD11_RS10795 a477dc14d6ebf7274d43a8542ca52cb1 530 SUPERFAMILY SSF50615 27 98 9.16E-22 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD11_RS10795 a477dc14d6ebf7274d43a8542ca52cb1 530 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 153 376 4.4E-67 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD11_RS10795 a477dc14d6ebf7274d43a8542ca52cb1 530 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 513 48.47 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 SMD11_RS10795 a477dc14d6ebf7274d43a8542ca52cb1 530 Gene3D G3DSA:2.40.30.20 5 97 5.3E-28 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 SMD11_RS10795 a477dc14d6ebf7274d43a8542ca52cb1 530 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 367 376 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD11_RS10795 a477dc14d6ebf7274d43a8542ca52cb1 530 Gene3D G3DSA:1.20.150.20 384 512 1.8E-51 T 06-07-2017 SMD11_RS10795 a477dc14d6ebf7274d43a8542ca52cb1 530 SUPERFAMILY SSF47917 384 512 2.49E-46 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD11_RS10795 a477dc14d6ebf7274d43a8542ca52cb1 530 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 383 508 1.8E-46 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD11_RS10795 a477dc14d6ebf7274d43a8542ca52cb1 530 SUPERFAMILY SSF52540 100 382 8.86E-93 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10795 a477dc14d6ebf7274d43a8542ca52cb1 530 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 1.6E-239 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 SMD11_RS10795 a477dc14d6ebf7274d43a8542ca52cb1 530 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 30 96 1.4E-14 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD11_RS10795 a477dc14d6ebf7274d43a8542ca52cb1 530 Gene3D G3DSA:3.40.50.300 99 383 5.6E-108 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18915 5b541f3c4bf7ce7baaf08f1c87827f5d 276 SUPERFAMILY SSF54821 106 205 5.23E-38 T 06-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18915 5b541f3c4bf7ce7baaf08f1c87827f5d 276 Gene3D G3DSA:3.30.1140.32 107 206 1.1E-42 T 06-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18915 5b541f3c4bf7ce7baaf08f1c87827f5d 276 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.89 T 06-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 SMD11_RS18915 5b541f3c4bf7ce7baaf08f1c87827f5d 276 SUPERFAMILY SSF54814 2 105 1.15E-34 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 SMD11_RS18915 5b541f3c4bf7ce7baaf08f1c87827f5d 276 Pfam PF07650 KH domain 38 109 4.7E-19 T 06-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18915 5b541f3c4bf7ce7baaf08f1c87827f5d 276 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 3.9E-37 T 06-07-2017 SMD11_RS18915 5b541f3c4bf7ce7baaf08f1c87827f5d 276 SMART SM00322 59 124 4.4E-7 T 06-07-2017 IPR004087 K Homology domain GO:0003676 SMD11_RS18915 5b541f3c4bf7ce7baaf08f1c87827f5d 276 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 06-07-2017 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18915 5b541f3c4bf7ce7baaf08f1c87827f5d 276 Gene3D G3DSA:3.30.300.20 17 106 1.7E-31 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta SMD11_RS18915 5b541f3c4bf7ce7baaf08f1c87827f5d 276 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 207 4.0E-93 T 06-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 SMD11_RS27395 11376fa57259a3605ca121d1fc7efa43 409 Pfam PF02441 Flavoprotein 12 137 2.6E-31 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD11_RS27395 11376fa57259a3605ca121d1fc7efa43 409 SUPERFAMILY SSF52507 7 183 2.35E-57 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD11_RS27395 11376fa57259a3605ca121d1fc7efa43 409 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 194 378 1.2E-69 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 SMD11_RS27395 11376fa57259a3605ca121d1fc7efa43 409 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 11 404 4.9E-118 T 06-07-2017 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 SMD11_RS27395 11376fa57259a3605ca121d1fc7efa43 409 Gene3D G3DSA:3.40.50.10300 193 408 3.0E-79 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 SMD11_RS27395 11376fa57259a3605ca121d1fc7efa43 409 SUPERFAMILY SSF102645 193 408 9.81E-67 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 SMD11_RS27395 11376fa57259a3605ca121d1fc7efa43 409 Gene3D G3DSA:3.40.50.1950 6 184 5.4E-60 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD11_RS17195 4e9f645082c204e6d1214935cfc02e7f 362 Pfam PF02254 TrkA-N domain 152 268 8.9E-26 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SMD11_RS17195 4e9f645082c204e6d1214935cfc02e7f 362 Gene3D G3DSA:3.40.50.720 143 282 1.2E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17195 4e9f645082c204e6d1214935cfc02e7f 362 SUPERFAMILY SSF81324 36 173 6.93E-22 T 06-07-2017 SMD11_RS17195 4e9f645082c204e6d1214935cfc02e7f 362 SUPERFAMILY SSF51735 147 290 5.26E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17195 4e9f645082c204e6d1214935cfc02e7f 362 Pfam PF07885 Ion channel 48 131 1.1E-13 T 06-07-2017 IPR013099 Potassium channel domain SMD11_RS17195 4e9f645082c204e6d1214935cfc02e7f 362 Gene3D G3DSA:1.10.287.70 47 139 1.8E-14 T 06-07-2017 SMD11_RS03210 40042bb28a8881147912a47fbe9a6a7e 424 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 125 296 1.8E-7 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 SMD11_RS03210 40042bb28a8881147912a47fbe9a6a7e 424 Gene3D G3DSA:3.20.20.60 101 336 1.6E-12 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS03210 40042bb28a8881147912a47fbe9a6a7e 424 SUPERFAMILY SSF51621 97 344 4.19E-14 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS17180 b54e9836948a88a99279bb6e75981ba9 472 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 244 469 5.1E-72 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD11_RS17180 b54e9836948a88a99279bb6e75981ba9 472 Gene3D G3DSA:2.40.50.100 5 84 4.1E-24 T 06-07-2017 SMD11_RS17180 b54e9836948a88a99279bb6e75981ba9 472 Pfam PF00364 Biotin-requiring enzyme 6 77 6.7E-17 T 06-07-2017 IPR000089 Biotin/lipoyl attachment SMD11_RS17180 b54e9836948a88a99279bb6e75981ba9 472 Gene3D G3DSA:3.30.559.10 241 469 6.9E-75 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 SMD11_RS17180 b54e9836948a88a99279bb6e75981ba9 472 Pfam PF02817 e3 binding domain 184 217 1.2E-14 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD11_RS17180 b54e9836948a88a99279bb6e75981ba9 472 SUPERFAMILY SSF51230 4 91 2.36E-24 T 06-07-2017 IPR011053 Single hybrid motif SMD11_RS17180 b54e9836948a88a99279bb6e75981ba9 472 SUPERFAMILY SSF52777 241 469 1.47E-71 T 06-07-2017 SMD11_RS17180 b54e9836948a88a99279bb6e75981ba9 472 Gene3D G3DSA:4.10.320.10 179 223 8.8E-18 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD11_RS17180 b54e9836948a88a99279bb6e75981ba9 472 SUPERFAMILY SSF47005 177 220 7.98E-12 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD11_RS03180 1bdfa3541f41b8ffbca4347180c251d9 412 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 315 405 6.4E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS03180 1bdfa3541f41b8ffbca4347180c251d9 412 Pfam PF07730 Histidine kinase 204 269 2.6E-19 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS03180 1bdfa3541f41b8ffbca4347180c251d9 412 SUPERFAMILY SSF55874 286 404 1.67E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS03180 1bdfa3541f41b8ffbca4347180c251d9 412 SMART SM00387 311 406 1.2E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS03180 1bdfa3541f41b8ffbca4347180c251d9 412 Gene3D G3DSA:3.30.565.10 318 406 1.3E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS25370 defa8a37a56a3f441ebf382b98dc1662 461 SUPERFAMILY SSF52540 3 195 3.48E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25370 defa8a37a56a3f441ebf382b98dc1662 461 SUPERFAMILY SSF52317 261 456 7.8E-33 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS25370 defa8a37a56a3f441ebf382b98dc1662 461 Gene3D G3DSA:3.40.50.300 2 192 1.9E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25370 defa8a37a56a3f441ebf382b98dc1662 461 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 1 448 42.474 T 06-07-2017 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 SMD11_RS25370 defa8a37a56a3f441ebf382b98dc1662 461 Gene3D G3DSA:3.40.50.880 264 459 5.4E-31 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS25370 defa8a37a56a3f441ebf382b98dc1662 461 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 265 445 1.1E-23 T 06-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 SMD11_RS25370 defa8a37a56a3f441ebf382b98dc1662 461 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 3 456 2.8E-121 T 06-07-2017 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 SMD11_RS25370 defa8a37a56a3f441ebf382b98dc1662 461 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 183 2.5E-25 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 Gene3D G3DSA:2.10.230.10 138 210 1.0E-19 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 SUPERFAMILY SSF49493 214 258 3.27E-20 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 SUPERFAMILY SSF49493 116 149 3.27E-20 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 4 350 1.7E-120 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 SUPERFAMILY SSF57938 131 211 2.62E-18 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 06-07-2017 IPR018253 DnaJ domain, conserved site SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 Pfam PF00684 DnaJ central domain 144 208 1.6E-12 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 Gene3D G3DSA:1.10.287.110 3 101 9.2E-33 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 Gene3D G3DSA:2.60.260.20 211 254 2.9E-22 T 06-07-2017 SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 Gene3D G3DSA:2.60.260.20 105 137 2.9E-22 T 06-07-2017 SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 Pfam PF00226 DnaJ domain 4 65 5.2E-26 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 375 37.978 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 SMART SM00271 3 60 5.6E-31 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 Pfam PF01556 DnaJ C terminal domain 119 334 3.4E-40 T 06-07-2017 IPR002939 Chaperone DnaJ, C-terminal SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 PRINTS PR00625 DnaJ domain signature 24 39 2.6E-24 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 PRINTS PR00625 DnaJ domain signature 60 79 2.6E-24 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 PRINTS PR00625 DnaJ domain signature 6 24 2.6E-24 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 PRINTS PR00625 DnaJ domain signature 40 60 2.6E-24 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 Gene3D G3DSA:2.60.260.20 257 334 9.7E-21 T 06-07-2017 SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 SUPERFAMILY SSF46565 3 100 2.09E-33 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS22625 e4f8478f6c6064a9b0ab0339f622b699 379 SUPERFAMILY SSF49493 260 345 2.75E-21 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMD11_RS17200 badac750b5bfd203141cf0ae5a2627ae 325 SUPERFAMILY SSF51735 111 287 6.54E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17200 badac750b5bfd203141cf0ae5a2627ae 325 Gene3D G3DSA:3.40.50.720 147 259 3.2E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17200 badac750b5bfd203141cf0ae5a2627ae 325 SUPERFAMILY SSF50129 1 140 1.25E-39 T 06-07-2017 IPR011032 GroES-like SMD11_RS17200 badac750b5bfd203141cf0ae5a2627ae 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 1.4E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS17200 badac750b5bfd203141cf0ae5a2627ae 325 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 324 4.8E-143 T 06-07-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 SMD11_RS17200 badac750b5bfd203141cf0ae5a2627ae 325 SMART SM00829 10 323 2.3E-49 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS17200 badac750b5bfd203141cf0ae5a2627ae 325 Pfam PF00107 Zinc-binding dehydrogenase 151 266 4.4E-29 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS17200 badac750b5bfd203141cf0ae5a2627ae 325 Gene3D G3DSA:3.90.180.10 1 146 1.2E-47 T 06-07-2017 IPR011032 GroES-like SMD11_RS30540 54fb4e87bccfc853e6dc2f445737bea6 282 Pfam PF12697 Alpha/beta hydrolase family 11 279 6.4E-23 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS30540 54fb4e87bccfc853e6dc2f445737bea6 282 Gene3D G3DSA:3.40.50.1820 10 281 1.9E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30540 54fb4e87bccfc853e6dc2f445737bea6 282 SUPERFAMILY SSF53474 6 281 1.34E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS00660 11899f9e6b1e228b980860399c329f10 481 SUPERFAMILY SSF89796 42 215 1.44E-17 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS00660 11899f9e6b1e228b980860399c329f10 481 Pfam PF02515 CoA-transferase family III 228 419 1.2E-38 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 SMD11_RS00660 11899f9e6b1e228b980860399c329f10 481 Gene3D G3DSA:3.40.50.10540 21 151 3.7E-4 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS00660 11899f9e6b1e228b980860399c329f10 481 Gene3D G3DSA:3.40.50.10540 225 424 1.5E-52 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS00660 11899f9e6b1e228b980860399c329f10 481 SUPERFAMILY SSF89796 227 420 1.83E-46 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS00345 b18b3487117f2defce4a4be250758657 359 Pfam PF00355 Rieske [2Fe-2S] domain 33 112 7.3E-14 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS00345 b18b3487117f2defce4a4be250758657 359 SUPERFAMILY SSF50022 29 138 7.46E-27 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS00345 b18b3487117f2defce4a4be250758657 359 Gene3D G3DSA:2.102.10.10 31 140 3.8E-24 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS03020 46e5513b53e306fe96ff441cd023e10a 405 SUPERFAMILY SSF53383 29 403 5.56E-120 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS03020 46e5513b53e306fe96ff441cd023e10a 405 Gene3D G3DSA:3.90.1150.10 21 73 3.1E-37 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS03020 46e5513b53e306fe96ff441cd023e10a 405 Gene3D G3DSA:3.90.1150.10 315 400 3.1E-37 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS03020 46e5513b53e306fe96ff441cd023e10a 405 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 230 268 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS03020 46e5513b53e306fe96ff441cd023e10a 405 Pfam PF00202 Aminotransferase class-III 36 399 1.4E-105 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS03020 46e5513b53e306fe96ff441cd023e10a 405 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 30 403 2.3E-138 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 SMD11_RS03020 46e5513b53e306fe96ff441cd023e10a 405 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 27 404 43.662 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 SMD11_RS03020 46e5513b53e306fe96ff441cd023e10a 405 Gene3D G3DSA:3.40.640.10 74 311 9.5E-86 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 Gene3D G3DSA:1.10.1200.10 1021 1089 2.1E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 SUPERFAMILY SSF52777 233 498 1.05E-64 T 06-07-2017 SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 Pfam PF00550 Phosphopantetheine attachment site 1019 1084 4.3E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 Pfam PF13193 AMP-binding enzyme C-terminal domain 917 992 3.4E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 SMART SM00823 Phosphopantetheine attachment site 1017 1088 1.1E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 Gene3D G3DSA:2.30.38.10 818 899 1.3E-28 T 06-07-2017 SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 534 933 1.1E-134 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 SUPERFAMILY SSF56801 470 1030 1.09E-160 T 06-07-2017 SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 Pfam PF00501 AMP-binding enzyme 514 909 6.1E-97 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 SUPERFAMILY SSF47336 1010 1084 3.01E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 SUPERFAMILY SSF52777 53 226 2.11E-48 T 06-07-2017 SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 Pfam PF00668 Condensation domain 50 343 1.4E-68 T 06-07-2017 IPR001242 Condensation domain SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1043 1058 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 Gene3D G3DSA:3.30.300.30 905 1020 5.4E-36 T 06-07-2017 SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 Gene3D G3DSA:3.40.50.980 663 804 1.3E-38 T 06-07-2017 SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 Gene3D G3DSA:3.40.50.980 509 662 4.5E-47 T 06-07-2017 SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 ProSitePatterns PS00455 Putative AMP-binding domain signature. 657 668 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS32930 c620141811af271a966da435f4fc13d2 1118 Pfam PF13745 HxxPF-repeated domain 366 458 2.1E-27 T 06-07-2017 SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 Gene3D G3DSA:2.60.120.10 6 139 5.1E-59 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 Gene3D G3DSA:2.60.120.10 245 280 5.1E-59 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 3 391 4.4E-73 T 06-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 Gene3D G3DSA:1.10.441.10 140 238 4.5E-21 T 06-07-2017 SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 Gene3D G3DSA:1.10.441.10 281 294 4.5E-21 T 06-07-2017 SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 PIRSF PIRSF001480 1 401 1.2E-94 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 Pfam PF01238 Phosphomannose isomerase type I 3 364 3.0E-68 T 06-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 Gene3D G3DSA:2.60.120.10 295 399 2.4E-15 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 PRINTS PR00714 Phosphomannose isomerase type I signature 31 46 6.0E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 PRINTS PR00714 Phosphomannose isomerase type I signature 243 262 6.0E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 PRINTS PR00714 Phosphomannose isomerase type I signature 227 242 6.0E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 PRINTS PR00714 Phosphomannose isomerase type I signature 262 281 6.0E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 PRINTS PR00714 Phosphomannose isomerase type I signature 80 101 6.0E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 PRINTS PR00714 Phosphomannose isomerase type I signature 125 148 6.0E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 6.0E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 PRINTS PR00714 Phosphomannose isomerase type I signature 281 300 6.0E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 125 133 - T 06-07-2017 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 SMD11_RS20730 6c13692f81abbdbf28c3a14cf2a3a422 401 SUPERFAMILY SSF51182 2 398 4.46E-94 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS03290 fa4d1028e3566650ce48943012dce894 149 SUPERFAMILY SSF54427 11 147 4.29E-25 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS03290 fa4d1028e3566650ce48943012dce894 149 Gene3D G3DSA:3.10.450.50 15 142 3.2E-17 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS03290 fa4d1028e3566650ce48943012dce894 149 Pfam PF13577 SnoaL-like domain 16 137 3.2E-11 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain SMD11_RS06645 46da1b93a479930c34936403ada39ea6 448 SUPERFAMILY SSF103473 240 432 1.83E-49 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS06645 46da1b93a479930c34936403ada39ea6 448 SUPERFAMILY SSF103473 3 193 1.83E-49 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS06645 46da1b93a479930c34936403ada39ea6 448 Pfam PF07690 Major Facilitator Superfamily 4 398 2.0E-42 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS06645 46da1b93a479930c34936403ada39ea6 448 Gene3D G3DSA:1.20.1250.20 4 183 2.0E-23 T 06-07-2017 SMD11_RS06645 46da1b93a479930c34936403ada39ea6 448 Gene3D G3DSA:1.20.1250.20 253 437 5.2E-11 T 06-07-2017 SMD11_RS25160 0a7711bf6d33586bfa032a97a240dd33 508 Gene3D G3DSA:3.40.50.720 22 208 2.8E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS25160 0a7711bf6d33586bfa032a97a240dd33 508 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 24 507 1.7E-202 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD11_RS25160 0a7711bf6d33586bfa032a97a240dd33 508 PIRSF PIRSF000110 6 508 2.2E-182 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD11_RS25160 0a7711bf6d33586bfa032a97a240dd33 508 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 26 209 3.1E-63 T 06-07-2017 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD11_RS25160 0a7711bf6d33586bfa032a97a240dd33 508 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 241 258 7.8E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD11_RS25160 0a7711bf6d33586bfa032a97a240dd33 508 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 348 374 7.8E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD11_RS25160 0a7711bf6d33586bfa032a97a240dd33 508 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 189 217 7.8E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD11_RS25160 0a7711bf6d33586bfa032a97a240dd33 508 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 259 275 7.8E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD11_RS25160 0a7711bf6d33586bfa032a97a240dd33 508 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 165 178 7.8E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD11_RS25160 0a7711bf6d33586bfa032a97a240dd33 508 SUPERFAMILY SSF51735 12 212 4.72E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS25160 0a7711bf6d33586bfa032a97a240dd33 508 Gene3D G3DSA:3.30.360.10 209 506 2.0E-122 T 06-07-2017 SMD11_RS25160 0a7711bf6d33586bfa032a97a240dd33 508 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 211 506 1.2E-115 T 06-07-2017 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD11_RS25160 0a7711bf6d33586bfa032a97a240dd33 508 SUPERFAMILY SSF55347 199 506 4.25E-115 T 06-07-2017 SMD11_RS25160 0a7711bf6d33586bfa032a97a240dd33 508 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 22 507 88.174 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD11_RS25160 0a7711bf6d33586bfa032a97a240dd33 508 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 199 205 - T 06-07-2017 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 SMD11_RS13615 6977e9f010cafa4be60f98b1f95adfdd 246 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 245 9.7E-44 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS13615 6977e9f010cafa4be60f98b1f95adfdd 246 Gene3D G3DSA:3.90.226.10 7 185 2.2E-46 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS13615 6977e9f010cafa4be60f98b1f95adfdd 246 Gene3D G3DSA:1.10.12.10 190 245 6.8E-13 T 06-07-2017 IPR014748 Crontonase, C-terminal SMD11_RS13615 6977e9f010cafa4be60f98b1f95adfdd 246 SUPERFAMILY SSF52096 6 245 5.18E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS13970 25631d068bef9c963d72484d8fe438a6 320 Pfam PF00294 pfkB family carbohydrate kinase 103 301 5.5E-28 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB SMD11_RS13970 25631d068bef9c963d72484d8fe438a6 320 Pfam PF00294 pfkB family carbohydrate kinase 12 73 6.8E-10 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB SMD11_RS13970 25631d068bef9c963d72484d8fe438a6 320 Gene3D G3DSA:3.40.1190.20 34 318 5.1E-78 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS13970 25631d068bef9c963d72484d8fe438a6 320 PIRSF PIRSF000535 1 320 1.5E-72 T 06-07-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SMD11_RS13970 25631d068bef9c963d72484d8fe438a6 320 SUPERFAMILY SSF53613 1 300 4.68E-60 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS13970 25631d068bef9c963d72484d8fe438a6 320 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMD11_RS13970 25631d068bef9c963d72484d8fe438a6 320 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 317 3.2E-84 T 06-07-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SMD11_RS23725 b1dd5afe957cb0c6d8155c22c7a9abfa 335 Gene3D G3DSA:3.40.50.150 81 222 2.0E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS23725 b1dd5afe957cb0c6d8155c22c7a9abfa 335 SUPERFAMILY SSF53335 61 225 8.56E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS23725 b1dd5afe957cb0c6d8155c22c7a9abfa 335 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 55 332 1.2E-101 T 06-07-2017 IPR015324 Ribosomal protein Rsm22, bacterial-type GO:0006412|GO:0008168 SMD11_RS23860 be5d5773319d25dc0ee4c8ecff0d0b3d 290 Gene3D G3DSA:3.40.50.1820 9 284 6.6E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS23860 be5d5773319d25dc0ee4c8ecff0d0b3d 290 Pfam PF12697 Alpha/beta hydrolase family 31 281 5.0E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS23860 be5d5773319d25dc0ee4c8ecff0d0b3d 290 SUPERFAMILY SSF53474 6 284 8.19E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS16285 38c3bde175d96e9979cd4fcbff63b878 322 Pfam PF02810 SEC-C motif 28 44 5.4E-8 T 06-07-2017 IPR004027 SEC-C motif SMD11_RS16285 38c3bde175d96e9979cd4fcbff63b878 322 Gene3D G3DSA:3.10.450.50 17 44 9.8E-8 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS16285 38c3bde175d96e9979cd4fcbff63b878 322 SUPERFAMILY SSF103642 25 44 1.1E-6 T 06-07-2017 SMD11_RS07795 71a2253f21bba7ccdb316392462347f3 196 Gene3D G3DSA:1.10.10.60 4 65 5.3E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS07795 71a2253f21bba7ccdb316392462347f3 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.0E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS07795 71a2253f21bba7ccdb316392462347f3 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.0E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS07795 71a2253f21bba7ccdb316392462347f3 196 Gene3D G3DSA:1.10.357.10 66 192 8.5E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS07795 71a2253f21bba7ccdb316392462347f3 196 SUPERFAMILY SSF48498 88 190 1.4E-14 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS07795 71a2253f21bba7ccdb316392462347f3 196 SUPERFAMILY SSF46689 7 79 1.08E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS07795 71a2253f21bba7ccdb316392462347f3 196 Pfam PF13305 WHG domain 91 171 3.9E-12 T 06-07-2017 IPR025996 WHG domain SMD11_RS07795 71a2253f21bba7ccdb316392462347f3 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 3.3E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 944 22.821 T 06-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 SUPERFAMILY SSF52540 618 913 9.15E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 Pfam PF00005 ABC transporter 628 864 5.9E-10 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 929 0.0 T 06-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 Gene3D G3DSA:3.30.1490.20 131 154 1.5E-24 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 Gene3D G3DSA:3.30.1490.20 201 240 1.5E-24 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 Gene3D G3DSA:1.10.8.280 290 411 3.2E-37 T 06-07-2017 SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 SUPERFAMILY SSF52540 435 574 1.81E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 SUPERFAMILY SSF52540 10 205 1.81E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 Gene3D G3DSA:1.20.1580.10 698 824 9.5E-55 T 06-07-2017 SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 Gene3D G3DSA:1.20.1580.10 255 288 2.0E-57 T 06-07-2017 SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 Gene3D G3DSA:1.20.1580.10 412 482 2.0E-57 T 06-07-2017 SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 Gene3D G3DSA:1.20.1580.10 92 130 2.0E-57 T 06-07-2017 SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 ProSitePatterns PS00211 ABC transporters family signature. 834 848 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 Gene3D G3DSA:3.40.50.300 6 90 1.7E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 Gene3D G3DSA:3.40.50.300 483 600 1.7E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 Gene3D G3DSA:3.40.50.300 825 942 4.8E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25065 f8ef7685632d2c2bb141e3c5bfbd9305 1037 Gene3D G3DSA:3.40.50.300 616 684 4.8E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00805 35fd6e00c178ed158952a0d1472453f1 491 Gene3D G3DSA:3.40.640.10 90 368 7.6E-87 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS00805 35fd6e00c178ed158952a0d1472453f1 491 SUPERFAMILY SSF53383 31 487 3.09E-111 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS00805 35fd6e00c178ed158952a0d1472453f1 491 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 53 415 8.7E-51 T 06-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 SMD11_RS00805 35fd6e00c178ed158952a0d1472453f1 491 Gene3D G3DSA:3.90.1150.10 369 487 8.5E-38 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS01000 ded285d5c45b559ab0ed80f870c545a6 216 SUPERFAMILY SSF53335 170 202 4.49E-15 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS01000 ded285d5c45b559ab0ed80f870c545a6 216 SUPERFAMILY SSF53335 22 140 4.49E-15 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS01000 ded285d5c45b559ab0ed80f870c545a6 216 Gene3D G3DSA:3.40.50.150 30 195 7.5E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS07895 319c74334a2fde329f35573f82914712 183 Gene3D G3DSA:1.10.10.10 40 174 4.8E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07895 319c74334a2fde329f35573f82914712 183 PRINTS PR00598 Bacterial regulatory protein MarR family signature 102 117 8.9E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS07895 319c74334a2fde329f35573f82914712 183 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 137 8.9E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS07895 319c74334a2fde329f35573f82914712 183 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 8.9E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS07895 319c74334a2fde329f35573f82914712 183 PRINTS PR00598 Bacterial regulatory protein MarR family signature 152 172 8.9E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS07895 319c74334a2fde329f35573f82914712 183 Pfam PF12802 MarR family 66 124 1.3E-12 T 06-07-2017 SMD11_RS07895 319c74334a2fde329f35573f82914712 183 SMART SM00347 61 161 2.5E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS07895 319c74334a2fde329f35573f82914712 183 SUPERFAMILY SSF46785 41 174 6.47E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 PRINTS PR00145 Argininosuccinate lyase family signature 285 301 9.5E-55 T 06-07-2017 SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 PRINTS PR00145 Argininosuccinate lyase family signature 110 132 9.5E-55 T 06-07-2017 SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 PRINTS PR00145 Argininosuccinate lyase family signature 320 339 9.5E-55 T 06-07-2017 SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 PRINTS PR00145 Argininosuccinate lyase family signature 151 171 9.5E-55 T 06-07-2017 SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 PRINTS PR00145 Argininosuccinate lyase family signature 202 218 9.5E-55 T 06-07-2017 SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 PRINTS PR00145 Argininosuccinate lyase family signature 241 265 9.5E-55 T 06-07-2017 SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 Gene3D G3DSA:1.10.275.10 10 115 5.0E-34 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 Hamap MF_00006 Argininosuccinate lyase [argH]. 10 463 40.601 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 ProSitePatterns PS00163 Fumarate lyases signature. 285 294 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 SUPERFAMILY SSF48557 14 463 2.83E-137 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 PRINTS PR00149 Fumarate lyase superfamily signature 241 268 3.9E-26 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 PRINTS PR00149 Fumarate lyase superfamily signature 111 129 3.9E-26 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 PRINTS PR00149 Fumarate lyase superfamily signature 156 174 3.9E-26 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 PRINTS PR00149 Fumarate lyase superfamily signature 285 301 3.9E-26 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 Pfam PF14698 Argininosuccinate lyase C-terminal 373 439 5.0E-22 T 06-07-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 Gene3D G3DSA:1.10.40.30 384 440 4.4E-28 T 06-07-2017 SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 Gene3D G3DSA:1.20.200.10 116 383 7.9E-99 T 06-07-2017 SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 Pfam PF00206 Lyase 22 310 4.5E-64 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal SMD11_RS26915 1ea69d0ddc16e3432e0a46a2cc9c7a72 477 TIGRFAM TIGR00838 argH: argininosuccinate lyase 11 465 2.4E-180 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS12560 cc52a977cbbfa2ac9b5ed916b20e033f 512 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 3 506 42.911 T 06-07-2017 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD11_RS12560 cc52a977cbbfa2ac9b5ed916b20e033f 512 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 06-07-2017 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 SMD11_RS12560 cc52a977cbbfa2ac9b5ed916b20e033f 512 Gene3D G3DSA:1.10.275.10 2 198 1.6E-70 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal SMD11_RS12560 cc52a977cbbfa2ac9b5ed916b20e033f 512 SUPERFAMILY SSF48557 3 504 1.41E-173 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 SMD11_RS12560 cc52a977cbbfa2ac9b5ed916b20e033f 512 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 4 505 3.3E-209 T 06-07-2017 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD11_RS12560 cc52a977cbbfa2ac9b5ed916b20e033f 512 Gene3D G3DSA:1.20.200.10 199 507 5.3E-112 T 06-07-2017 SMD11_RS12560 cc52a977cbbfa2ac9b5ed916b20e033f 512 Pfam PF00221 Aromatic amino acid lyase 12 472 2.9E-177 T 06-07-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 SMD11_RS07605 3e3b34b92ea7e830333f06edb20f8942 184 Pfam PF05685 Putative restriction endonuclease 25 180 8.6E-18 T 06-07-2017 IPR008538 Domain of unknown function DUF820 SMD11_RS07605 3e3b34b92ea7e830333f06edb20f8942 184 Gene3D G3DSA:3.90.1570.10 25 152 3.6E-12 T 06-07-2017 IPR012296 Nuclease, putative, TT1808 SMD11_RS07605 3e3b34b92ea7e830333f06edb20f8942 184 SUPERFAMILY SSF52980 26 156 1.02E-12 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD11_RS04840 066e79483cebd82a9912e381fe4e8643 954 Gene3D G3DSA:2.120.10.30 642 743 6.3E-8 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS04840 066e79483cebd82a9912e381fe4e8643 954 Gene3D G3DSA:2.120.10.30 794 858 6.3E-8 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS04840 066e79483cebd82a9912e381fe4e8643 954 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 458 612 1.4E-28 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 SMD11_RS04840 066e79483cebd82a9912e381fe4e8643 954 Gene3D G3DSA:1.10.390.10 460 614 2.0E-24 T 06-07-2017 SMD11_RS04840 066e79483cebd82a9912e381fe4e8643 954 SUPERFAMILY SSF55486 292 612 4.4E-64 T 06-07-2017 SMD11_RS04840 066e79483cebd82a9912e381fe4e8643 954 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 446 462 2.9E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS04840 066e79483cebd82a9912e381fe4e8643 954 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 467 478 2.9E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS04840 066e79483cebd82a9912e381fe4e8643 954 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 411 431 2.9E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS04840 066e79483cebd82a9912e381fe4e8643 954 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 538 554 2.9E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS04840 066e79483cebd82a9912e381fe4e8643 954 SUPERFAMILY SSF63825 664 865 8.89E-5 T 06-07-2017 SMD11_RS04840 066e79483cebd82a9912e381fe4e8643 954 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 294 455 1.1E-38 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS04840 066e79483cebd82a9912e381fe4e8643 954 Gene3D G3DSA:3.10.170.10 293 459 1.1E-36 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS05365 36f5967a1cdf49497205377e08d5dc01 261 Pfam PF01066 CDP-alcohol phosphatidyltransferase 50 114 5.3E-7 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD11_RS05555 7a95129ae6c7ea64bfd4684992c311a6 270 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 48 105 1.7E-6 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS05555 7a95129ae6c7ea64bfd4684992c311a6 270 Gene3D G3DSA:3.40.47.10 48 119 2.1E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS05555 7a95129ae6c7ea64bfd4684992c311a6 270 SUPERFAMILY SSF53901 75 267 2.05E-45 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS05555 7a95129ae6c7ea64bfd4684992c311a6 270 Gene3D G3DSA:3.40.47.10 137 266 4.6E-32 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS05555 7a95129ae6c7ea64bfd4684992c311a6 270 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 116 225 1.1E-18 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS19235 fd25ec6d8f780b457a0c95e4886e6236 237 Pfam PF03473 MOSC domain 76 187 2.8E-21 T 06-07-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 SMD11_RS19235 fd25ec6d8f780b457a0c95e4886e6236 237 Gene3D G3DSA:2.40.33.20 15 232 2.5E-68 T 06-07-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like SMD11_RS19235 fd25ec6d8f780b457a0c95e4886e6236 237 SUPERFAMILY SSF50800 19 229 1.94E-51 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain SMD11_RS12090 fe499056f06b0bf4c2291ef2ec1090d2 139 SUPERFAMILY SSF55874 50 137 5.52E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS12090 fe499056f06b0bf4c2291ef2ec1090d2 139 Pfam PF13581 Histidine kinase-like ATPase domain 22 132 1.6E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS13030 cffddd2ce2b75f2eab74c52ce708ef8d 548 Pfam PF01642 Methylmalonyl-CoA mutase 25 540 7.0E-217 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS13030 cffddd2ce2b75f2eab74c52ce708ef8d 548 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 25 546 1.2E-229 T 06-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS13030 cffddd2ce2b75f2eab74c52ce708ef8d 548 Gene3D G3DSA:3.20.20.240 25 542 7.1E-221 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS13030 cffddd2ce2b75f2eab74c52ce708ef8d 548 SUPERFAMILY SSF51703 23 542 2.94E-203 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS07110 99d470eb091f7c175365f2f9ff012dfc 580 SUPERFAMILY SSF50494 73 261 8.07E-15 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS07110 99d470eb091f7c175365f2f9ff012dfc 580 SUPERFAMILY SSF69318 221 425 5.49E-10 T 06-07-2017 SMD11_RS07110 99d470eb091f7c175365f2f9ff012dfc 580 Gene3D G3DSA:2.40.10.10 86 189 1.6E-10 T 06-07-2017 SMD11_RS07110 99d470eb091f7c175365f2f9ff012dfc 580 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 333 396 1.4E-7 T 06-07-2017 SMD11_RS07110 99d470eb091f7c175365f2f9ff012dfc 580 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 108 113 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD11_RS07110 99d470eb091f7c175365f2f9ff012dfc 580 Pfam PF00089 Trypsin 84 247 1.5E-6 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 SMART SM00996 9 484 0.0 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 SUPERFAMILY SSF51735 243 405 1.79E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 PIRSF PIRSF001109 1 485 2.8E-192 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 SUPERFAMILY SSF52283 406 485 4.53E-114 T 06-07-2017 SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 SUPERFAMILY SSF52283 8 157 4.53E-114 T 06-07-2017 SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 SUPERFAMILY SSF52283 195 242 4.53E-114 T 06-07-2017 SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 5 477 49.4 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 9 484 4.1E-148 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 10 477 3.8E-192 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 Gene3D G3DSA:3.40.50.1480 406 485 4.1E-148 T 06-07-2017 SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 Gene3D G3DSA:3.40.50.1480 8 244 4.1E-148 T 06-07-2017 SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 265 281 - T 06-07-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 Gene3D G3DSA:3.40.50.720 245 404 9.7E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 243 405 1.1E-82 T 06-07-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 SMART SM00997 243 405 5.0E-109 T 06-07-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD11_RS20745 cb66f7c6c8169ffaf97d5aba824d0854 485 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 81 95 - T 06-07-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 SMD11_RS01585 83f0450936c10cdbdcc9fdafa32b98e2 314 SUPERFAMILY SSF55729 194 306 1.5E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS01585 83f0450936c10cdbdcc9fdafa32b98e2 314 SUPERFAMILY SSF55729 1 106 6.82E-6 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS01585 83f0450936c10cdbdcc9fdafa32b98e2 314 Pfam PF00583 Acetyltransferase (GNAT) family 228 301 1.4E-6 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS01585 83f0450936c10cdbdcc9fdafa32b98e2 314 Gene3D G3DSA:3.40.630.30 191 306 7.2E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS01585 83f0450936c10cdbdcc9fdafa32b98e2 314 Gene3D G3DSA:3.40.630.30 2 101 6.8E-5 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS26210 181dc0bc800543b6bbdddd774ef0150c 205 Gene3D G3DSA:1.10.10.60 17 63 1.1E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS26210 181dc0bc800543b6bbdddd774ef0150c 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS26210 181dc0bc800543b6bbdddd774ef0150c 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS26210 181dc0bc800543b6bbdddd774ef0150c 205 Gene3D G3DSA:1.10.357.10 64 203 4.9E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS26210 181dc0bc800543b6bbdddd774ef0150c 205 SUPERFAMILY SSF46689 17 91 6.67E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS26210 181dc0bc800543b6bbdddd774ef0150c 205 SUPERFAMILY SSF48498 90 201 1.72E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS26210 181dc0bc800543b6bbdddd774ef0150c 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 65 5.6E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS06370 28eeb11c48786e3bf03c24fa80916d87 555 Gene3D G3DSA:3.40.50.980 206 357 1.7E-36 T 06-07-2017 SMD11_RS06370 28eeb11c48786e3bf03c24fa80916d87 555 Gene3D G3DSA:3.40.50.980 32 205 3.4E-30 T 06-07-2017 SMD11_RS06370 28eeb11c48786e3bf03c24fa80916d87 555 Gene3D G3DSA:3.30.300.30 445 548 1.7E-30 T 06-07-2017 SMD11_RS06370 28eeb11c48786e3bf03c24fa80916d87 555 Pfam PF00501 AMP-binding enzyme 38 450 1.4E-83 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS06370 28eeb11c48786e3bf03c24fa80916d87 555 Pfam PF13193 AMP-binding enzyme C-terminal domain 459 536 7.4E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS06370 28eeb11c48786e3bf03c24fa80916d87 555 ProSitePatterns PS00455 Putative AMP-binding domain signature. 202 213 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS06370 28eeb11c48786e3bf03c24fa80916d87 555 TIGRFAM TIGR02275 DHB_AMP_lig: (2,3-dihydroxybenzoyl)adenylate synthase 14 543 1.2E-229 T 06-07-2017 IPR011963 2,3-dihydroxybenzoate-AMP ligase GO:0008668|GO:0019290 SMD11_RS06370 28eeb11c48786e3bf03c24fa80916d87 555 SUPERFAMILY SSF56801 18 546 8.9E-140 T 06-07-2017 SMD11_RS06370 28eeb11c48786e3bf03c24fa80916d87 555 Gene3D G3DSA:2.30.38.10 369 444 3.3E-23 T 06-07-2017 SMD11_RS28765 6a8dcf5099fe995e22e01ee4de501ff4 246 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 4 209 24.864 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 SMD11_RS28765 6a8dcf5099fe995e22e01ee4de501ff4 246 PIRSF PIRSF006755 4 210 5.1E-39 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 SMD11_RS28765 6a8dcf5099fe995e22e01ee4de501ff4 246 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 9 172 1.6E-34 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 SMD11_RS28765 6a8dcf5099fe995e22e01ee4de501ff4 246 SUPERFAMILY SSF52540 6 204 2.76E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28765 6a8dcf5099fe995e22e01ee4de501ff4 246 Gene3D G3DSA:3.40.50.300 6 207 2.5E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28765 6a8dcf5099fe995e22e01ee4de501ff4 246 Pfam PF13500 AAA domain 7 204 1.4E-34 T 06-07-2017 SMD11_RS31995 c54a0a8737549507aa33521bf893012a 513 Gene3D G3DSA:3.30.300.30 407 506 7.7E-24 T 06-07-2017 SMD11_RS31995 c54a0a8737549507aa33521bf893012a 513 Gene3D G3DSA:2.30.38.10 331 403 1.2E-27 T 06-07-2017 SMD11_RS31995 c54a0a8737549507aa33521bf893012a 513 Gene3D G3DSA:3.40.50.980 21 182 1.2E-23 T 06-07-2017 SMD11_RS31995 c54a0a8737549507aa33521bf893012a 513 SUPERFAMILY SSF56801 10 509 1.11E-118 T 06-07-2017 SMD11_RS31995 c54a0a8737549507aa33521bf893012a 513 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 496 2.2E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS31995 c54a0a8737549507aa33521bf893012a 513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS31995 c54a0a8737549507aa33521bf893012a 513 Gene3D G3DSA:3.40.50.980 203 315 7.3E-23 T 06-07-2017 SMD11_RS31995 c54a0a8737549507aa33521bf893012a 513 Pfam PF00501 AMP-binding enzyme 21 412 1.4E-76 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS03585 4162b0daf9277627472114deb9a086d1 593 Gene3D G3DSA:1.20.1560.10 34 343 4.5E-50 T 06-07-2017 SMD11_RS03585 4162b0daf9277627472114deb9a086d1 593 SUPERFAMILY SSF90123 34 346 1.57E-51 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS03585 4162b0daf9277627472114deb9a086d1 593 Gene3D G3DSA:3.40.50.300 356 586 1.4E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03585 4162b0daf9277627472114deb9a086d1 593 Pfam PF00664 ABC transporter transmembrane region 44 313 9.1E-27 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS03585 4162b0daf9277627472114deb9a086d1 593 SUPERFAMILY SSF52540 352 591 1.03E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03585 4162b0daf9277627472114deb9a086d1 593 SMART SM00382 381 567 9.9E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS03585 4162b0daf9277627472114deb9a086d1 593 Pfam PF00005 ABC transporter 372 521 2.4E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS01005 ec9bb3b01b488c1e2364da21834d4323 649 SUPERFAMILY SSF54373 217 320 9.42E-15 T 06-07-2017 SMD11_RS01005 ec9bb3b01b488c1e2364da21834d4323 649 Gene3D G3DSA:3.30.9.10 61 148 5.3E-33 T 06-07-2017 SMD11_RS01005 ec9bb3b01b488c1e2364da21834d4323 649 Gene3D G3DSA:3.30.9.10 214 320 5.3E-33 T 06-07-2017 SMD11_RS01005 ec9bb3b01b488c1e2364da21834d4323 649 SUPERFAMILY SSF51905 320 380 2.2E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01005 ec9bb3b01b488c1e2364da21834d4323 649 SUPERFAMILY SSF51905 3 218 2.2E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01005 ec9bb3b01b488c1e2364da21834d4323 649 Gene3D G3DSA:3.50.50.60 323 379 6.1E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01005 ec9bb3b01b488c1e2364da21834d4323 649 Gene3D G3DSA:3.50.50.60 149 210 6.1E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01005 ec9bb3b01b488c1e2364da21834d4323 649 Gene3D G3DSA:3.50.50.60 2 58 6.1E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01005 ec9bb3b01b488c1e2364da21834d4323 649 Pfam PF01266 FAD dependent oxidoreductase 5 356 1.3E-41 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD11_RS01005 ec9bb3b01b488c1e2364da21834d4323 649 SUPERFAMILY SSF55469 462 645 9.99E-8 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS01005 ec9bb3b01b488c1e2364da21834d4323 649 Pfam PF00881 Nitroreductase family 550 643 1.4E-5 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMD11_RS01005 ec9bb3b01b488c1e2364da21834d4323 649 Gene3D G3DSA:3.40.109.10 458 645 6.7E-7 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS28240 e12b2d751624fe4afc93d572757f7bf3 337 Pfam PF00892 EamA-like transporter family 13 142 8.3E-13 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS28240 e12b2d751624fe4afc93d572757f7bf3 337 Pfam PF00892 EamA-like transporter family 155 298 1.0E-13 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS28240 e12b2d751624fe4afc93d572757f7bf3 337 SUPERFAMILY SSF103481 229 301 1.15E-9 T 06-07-2017 SMD11_RS28240 e12b2d751624fe4afc93d572757f7bf3 337 SUPERFAMILY SSF103481 47 143 1.44E-10 T 06-07-2017 SMD11_RS20185 a13801f6836bc701b0c59a3cf7579f62 429 Pfam PF07730 Histidine kinase 184 249 1.5E-17 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS20185 a13801f6836bc701b0c59a3cf7579f62 429 SUPERFAMILY SSF55874 305 422 1.67E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 SMART SM00825 Beta-ketoacyl synthase 37 464 1.1E-190 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 Pfam PF00550 Phosphopantetheine attachment site 1702 1767 1.2E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 Pfam PF14765 Polyketide synthase dehydratase 926 1208 4.8E-48 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1407 1586 9.8E-50 T 06-07-2017 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 Gene3D G3DSA:3.30.70.250 687 751 2.0E-6 T 06-07-2017 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 286 1.2E-84 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 294 411 8.2E-42 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 SUPERFAMILY SSF51735 1405 1620 6.1E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 Gene3D G3DSA:3.40.47.10 299 462 6.3E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 414 525 4.8E-15 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 SUPERFAMILY SSF53901 32 407 8.46E-98 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 Pfam PF08990 Erythronolide synthase docking 8 28 8.3E-6 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 Pfam PF00698 Acyl transferase domain 565 878 1.9E-55 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 SMART SM00826 926 1092 7.1E-61 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 Gene3D G3DSA:3.40.366.10 558 683 7.0E-76 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 Gene3D G3DSA:3.40.366.10 752 872 7.0E-76 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1726 1741 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 SUPERFAMILY SSF51735 1222 1387 3.94E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 Gene3D G3DSA:1.10.1200.10 1697 1771 1.1E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 Gene3D G3DSA:3.40.50.720 1406 1610 2.1E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 SUPERFAMILY SSF52151 752 844 4.71E-71 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 SUPERFAMILY SSF52151 563 688 4.71E-71 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 SUPERFAMILY SSF55048 687 751 1.83E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 Pfam PF08659 KR domain 1407 1584 7.2E-62 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 565 858 1.7E-113 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 SMART SM01294 1700 1767 2.5E-4 T 06-07-2017 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 Gene3D G3DSA:3.40.47.10 37 298 8.4E-90 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 SUPERFAMILY SSF47336 1691 1779 4.58E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS00845 a65a2ad003312e5f588ba216f98bae18 1855 SMART SM00823 Phosphopantetheine attachment site 1699 1771 2.1E-31 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS27510 37779843ec1dc009ed990580da3b4fd6 426 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 226 411 5.8E-72 T 06-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMD11_RS27510 37779843ec1dc009ed990580da3b4fd6 426 SUPERFAMILY SSF142695 219 391 2.75E-67 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMD11_RS27510 37779843ec1dc009ed990580da3b4fd6 426 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 16 213 1.6E-73 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD11_RS27510 37779843ec1dc009ed990580da3b4fd6 426 Gene3D G3DSA:3.90.870.10 10 223 2.4E-95 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain SMD11_RS27510 37779843ec1dc009ed990580da3b4fd6 426 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 19 212 4.0E-84 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD11_RS27510 37779843ec1dc009ed990580da3b4fd6 426 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 218 414 40.276 T 06-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMD11_RS27510 37779843ec1dc009ed990580da3b4fd6 426 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 14 410 54.137 T 06-07-2017 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMD11_RS27510 37779843ec1dc009ed990580da3b4fd6 426 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 13 217 38.704 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD11_RS27510 37779843ec1dc009ed990580da3b4fd6 426 Pfam PF00925 GTP cyclohydrolase II 222 387 6.9E-70 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 SMD11_RS27510 37779843ec1dc009ed990580da3b4fd6 426 PIRSF PIRSF001259 13 420 1.4E-171 T 06-07-2017 SMD11_RS27510 37779843ec1dc009ed990580da3b4fd6 426 SUPERFAMILY SSF55821 11 215 8.01E-82 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain SMD11_RS07820 5b8627c8a6302647f5faccffc896db23 240 Pfam PF08241 Methyltransferase domain 53 148 3.5E-28 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS07820 5b8627c8a6302647f5faccffc896db23 240 Gene3D G3DSA:3.40.50.150 13 200 1.8E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS07820 5b8627c8a6302647f5faccffc896db23 240 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 11 198 3.5E-51 T 06-07-2017 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 SMD11_RS07820 5b8627c8a6302647f5faccffc896db23 240 SUPERFAMILY SSF53335 7 202 2.32E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS07515 7f081f1c9d9376cc2023c771de988a44 502 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 88 233 5.1E-15 T 06-07-2017 SMD11_RS04140 d42639d34e76e79c41c48ba84360c621 708 SUPERFAMILY SSF55781 222 339 1.4E-12 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS04140 d42639d34e76e79c41c48ba84360c621 708 Pfam PF13581 Histidine kinase-like ATPase domain 594 701 5.5E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS04140 d42639d34e76e79c41c48ba84360c621 708 SUPERFAMILY SSF81606 374 579 1.62E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS04140 d42639d34e76e79c41c48ba84360c621 708 SMART SM00091 27 93 0.0089 T 06-07-2017 IPR000014 PAS domain SMD11_RS04140 d42639d34e76e79c41c48ba84360c621 708 Pfam PF01590 GAF domain 226 328 1.9E-7 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS04140 d42639d34e76e79c41c48ba84360c621 708 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 386 580 5.9E-54 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS04140 d42639d34e76e79c41c48ba84360c621 708 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 32 149 3.2E-6 T 06-07-2017 IPR000014 PAS domain SMD11_RS04140 d42639d34e76e79c41c48ba84360c621 708 SUPERFAMILY SSF55874 624 702 2.69E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS04140 d42639d34e76e79c41c48ba84360c621 708 SMART SM00331 359 580 2.2E-35 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS04140 d42639d34e76e79c41c48ba84360c621 708 Gene3D G3DSA:3.30.450.20 29 140 2.2E-16 T 06-07-2017 SMD11_RS04140 d42639d34e76e79c41c48ba84360c621 708 Gene3D G3DSA:3.30.450.40 153 336 1.1E-31 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS04140 d42639d34e76e79c41c48ba84360c621 708 Pfam PF08448 PAS fold 34 142 6.2E-13 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS04140 d42639d34e76e79c41c48ba84360c621 708 SMART SM00065 160 338 8.4E-6 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS04140 d42639d34e76e79c41c48ba84360c621 708 SUPERFAMILY SSF55785 29 140 5.93E-12 T 06-07-2017 IPR000014 PAS domain SMD11_RS01805 586cd9e85663de2610b22845e62be85c 193 SUPERFAMILY SSF55729 48 173 7.62E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS01805 586cd9e85663de2610b22845e62be85c 193 Pfam PF13302 Acetyltransferase (GNAT) domain 53 162 3.4E-14 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS01805 586cd9e85663de2610b22845e62be85c 193 Gene3D G3DSA:3.40.630.30 67 170 2.0E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS09600 61ee01ba4e430da5cc2930d0a10efe5b 79 Gene3D G3DSA:3.30.300.120 5 63 1.1E-5 T 06-07-2017 SMD11_RS09600 61ee01ba4e430da5cc2930d0a10efe5b 79 Pfam PF13083 KH domain 3 64 2.5E-19 T 06-07-2017 SMD11_RS09600 61ee01ba4e430da5cc2930d0a10efe5b 79 Hamap MF_00088 UPF0109 protein . 2 73 21.623 T 06-07-2017 IPR020627 Uncharacterised protein family UPF0109 SMD11_RS09600 61ee01ba4e430da5cc2930d0a10efe5b 79 SUPERFAMILY SSF54814 16 62 2.16E-8 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 SUPERFAMILY SSF53671 4 331 1.19E-94 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 332 80.524 T 06-07-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 310 321 2.3E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 2.3E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 2.3E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 2.3E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 2.3E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 331 3.5E-120 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 329 7.6E-50 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 Gene3D G3DSA:3.40.50.1370 3 144 5.1E-54 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 5.9E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 296 319 5.9E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 5.9E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 5.9E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 Gene3D G3DSA:3.40.50.1370 145 318 2.8E-67 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS07935 315ddd2e6a38816181397caaef366550 334 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 8.2E-45 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 SMD11_RS07830 8124a3bf7f3b4b76e579dc5ca5f01112 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 9.0E-5 T 06-07-2017 SMD11_RS07830 8124a3bf7f3b4b76e579dc5ca5f01112 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 347 362 9.0E-5 T 06-07-2017 SMD11_RS07830 8124a3bf7f3b4b76e579dc5ca5f01112 387 SUPERFAMILY SSF51971 3 232 2.24E-25 T 06-07-2017 SMD11_RS07830 8124a3bf7f3b4b76e579dc5ca5f01112 387 SUPERFAMILY SSF51971 323 383 2.24E-25 T 06-07-2017 SMD11_RS07830 8124a3bf7f3b4b76e579dc5ca5f01112 387 Pfam PF01266 FAD dependent oxidoreductase 4 213 3.9E-9 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD11_RS07830 8124a3bf7f3b4b76e579dc5ca5f01112 387 Gene3D G3DSA:3.40.50.720 169 234 2.8E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS07830 8124a3bf7f3b4b76e579dc5ca5f01112 387 Gene3D G3DSA:3.40.50.720 333 383 2.8E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS07830 8124a3bf7f3b4b76e579dc5ca5f01112 387 Gene3D G3DSA:3.40.50.720 3 75 2.8E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19140 f97fb2a43a7369b0b7162306e93c68d7 149 Pfam PF13581 Histidine kinase-like ATPase domain 23 118 2.0E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS19140 f97fb2a43a7369b0b7162306e93c68d7 149 SUPERFAMILY SSF55874 50 139 8.09E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 SUPERFAMILY SSF47336 551 661 2.36E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Gene3D G3DSA:3.40.50.980 205 357 2.1E-17 T 06-07-2017 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Gene3D G3DSA:3.30.70.250 1309 1371 2.0E-6 T 06-07-2017 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 SMART SM00825 Beta-ketoacyl synthase 648 1075 3.1E-200 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1182 1485 4.5E-106 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Gene3D G3DSA:3.40.50.980 25 137 3.7E-24 T 06-07-2017 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Gene3D G3DSA:3.40.50.980 179 204 3.7E-24 T 06-07-2017 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Pfam PF00501 AMP-binding enzyme 30 438 2.2E-69 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 SUPERFAMILY SSF55048 1309 1372 1.83E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 ProSitePatterns PS00012 Phosphopantetheine attachment site. 585 600 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 904 1021 6.9E-45 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Gene3D G3DSA:3.30.300.30 434 532 6.0E-14 T 06-07-2017 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Pfam PF00550 Phosphopantetheine attachment site 1580 1644 6.4E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Pfam PF00550 Phosphopantetheine attachment site 559 625 8.2E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Gene3D G3DSA:3.40.366.10 1174 1305 4.1E-69 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Gene3D G3DSA:3.40.366.10 1373 1499 4.1E-69 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 646 896 5.5E-81 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Gene3D G3DSA:3.40.47.10 644 908 8.5E-81 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 SUPERFAMILY SSF53901 643 1020 3.09E-93 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 SUPERFAMILY SSF56801 24 535 4.45E-106 T 06-07-2017 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Gene3D G3DSA:1.10.1200.10 1577 1649 4.3E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Gene3D G3DSA:1.10.1200.10 554 628 9.9E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 SMART SM00823 Phosphopantetheine attachment site 557 630 8.1E-21 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 SMART SM00823 Phosphopantetheine attachment site 1577 1648 7.2E-22 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Gene3D G3DSA:2.30.38.10 358 427 2.6E-26 T 06-07-2017 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1024 1143 5.2E-17 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 SUPERFAMILY SSF52151 1374 1470 1.05E-64 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 SUPERFAMILY SSF52151 1180 1310 1.05E-64 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 SUPERFAMILY SSF47336 1571 1656 1.31E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Gene3D G3DSA:3.40.47.10 909 1076 3.4E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32350 8ec25c43a1e49c9fd4140b04b982457d 1720 Pfam PF00698 Acyl transferase domain 1182 1503 4.3E-51 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS24645 efba275c8edabfefce5db637895b08a7 324 SMART SM00382 38 222 1.3E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS24645 efba275c8edabfefce5db637895b08a7 324 Gene3D G3DSA:3.40.50.300 3 239 1.1E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24645 efba275c8edabfefce5db637895b08a7 324 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS24645 efba275c8edabfefce5db637895b08a7 324 SUPERFAMILY SSF52540 22 237 2.61E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24645 efba275c8edabfefce5db637895b08a7 324 Pfam PF00005 ABC transporter 30 173 5.1E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS24345 366c49ebb67264abf72a950ebcb60421 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 215 2.0E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24345 366c49ebb67264abf72a950ebcb60421 223 Gene3D G3DSA:1.10.10.10 161 220 3.1E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS24345 366c49ebb67264abf72a950ebcb60421 223 SUPERFAMILY SSF46894 148 220 9.18E-24 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS24345 366c49ebb67264abf72a950ebcb60421 223 SMART SM00421 158 215 1.0E-26 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24345 366c49ebb67264abf72a950ebcb60421 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 1.1E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24345 366c49ebb67264abf72a950ebcb60421 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 1.1E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24345 366c49ebb67264abf72a950ebcb60421 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 1.1E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24345 366c49ebb67264abf72a950ebcb60421 223 SUPERFAMILY SSF52172 6 122 2.7E-31 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS24345 366c49ebb67264abf72a950ebcb60421 223 Pfam PF00072 Response regulator receiver domain 9 120 2.3E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS24345 366c49ebb67264abf72a950ebcb60421 223 SMART SM00448 7 119 4.6E-33 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS24345 366c49ebb67264abf72a950ebcb60421 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24345 366c49ebb67264abf72a950ebcb60421 223 Gene3D G3DSA:3.40.50.2300 5 160 3.1E-35 T 06-07-2017 SMD11_RS18450 563987551e0c62a67257adff9bece4aa 437 Pfam PF00375 Sodium:dicarboxylate symporter family 21 408 8.4E-109 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS18450 563987551e0c62a67257adff9bece4aa 437 SUPERFAMILY SSF118215 21 409 1.06E-99 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS18450 563987551e0c62a67257adff9bece4aa 437 Gene3D G3DSA:1.10.3860.10 16 413 1.2E-105 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS18450 563987551e0c62a67257adff9bece4aa 437 PRINTS PR00173 Glutamate-aspartate symporter signature 338 357 5.9E-25 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS18450 563987551e0c62a67257adff9bece4aa 437 PRINTS PR00173 Glutamate-aspartate symporter signature 303 329 5.9E-25 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS18450 563987551e0c62a67257adff9bece4aa 437 PRINTS PR00173 Glutamate-aspartate symporter signature 61 81 5.9E-25 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS18450 563987551e0c62a67257adff9bece4aa 437 PRINTS PR00173 Glutamate-aspartate symporter signature 91 116 5.9E-25 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS18450 563987551e0c62a67257adff9bece4aa 437 PRINTS PR00173 Glutamate-aspartate symporter signature 364 384 5.9E-25 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS18450 563987551e0c62a67257adff9bece4aa 437 PRINTS PR00173 Glutamate-aspartate symporter signature 201 220 5.9E-25 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS18450 563987551e0c62a67257adff9bece4aa 437 PRINTS PR00173 Glutamate-aspartate symporter signature 19 39 5.9E-25 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS18450 563987551e0c62a67257adff9bece4aa 437 PRINTS PR00173 Glutamate-aspartate symporter signature 236 255 5.9E-25 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS32080 b2c98ec7f7607f1383ff5e258c753f9a 408 Gene3D G3DSA:1.20.144.10 51 145 2.4E-15 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS32080 b2c98ec7f7607f1383ff5e258c753f9a 408 SUPERFAMILY SSF48317 27 400 1.09E-60 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS32080 b2c98ec7f7607f1383ff5e258c753f9a 408 Pfam PF01569 PAP2 superfamily 268 403 2.1E-7 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS32080 b2c98ec7f7607f1383ff5e258c753f9a 408 Gene3D G3DSA:1.10.606.10 146 406 4.3E-63 T 06-07-2017 IPR016119 Bromoperoxidase/chloroperoxidase, C-terminal GO:0004601|GO:0055114 SMD11_RS30150 10db17bb76192df9bf1a7d16f5ee29e2 488 Gene3D G3DSA:1.10.10.10 416 478 3.4E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30150 10db17bb76192df9bf1a7d16f5ee29e2 488 SUPERFAMILY SSF46894 412 478 4.42E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS30150 10db17bb76192df9bf1a7d16f5ee29e2 488 SMART SM00421 422 479 2.6E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS30150 10db17bb76192df9bf1a7d16f5ee29e2 488 Gene3D G3DSA:1.25.40.10 87 184 7.4E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS30150 10db17bb76192df9bf1a7d16f5ee29e2 488 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 455 467 7.5E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS30150 10db17bb76192df9bf1a7d16f5ee29e2 488 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 425 439 7.5E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS30150 10db17bb76192df9bf1a7d16f5ee29e2 488 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 439 455 7.5E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS30150 10db17bb76192df9bf1a7d16f5ee29e2 488 Pfam PF00196 Bacterial regulatory proteins, luxR family 424 477 4.8E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS25765 44970a162c81f8480169119dabc0e655 306 SUPERFAMILY SSF111331 11 302 1.96E-77 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMD11_RS25765 44970a162c81f8480169119dabc0e655 306 Pfam PF01513 ATP-NAD kinase 71 280 1.3E-55 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 SMD11_RS25765 44970a162c81f8480169119dabc0e655 306 Hamap MF_00361 NAD kinase [nadK]. 10 296 29.53 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 SMD11_RS25765 44970a162c81f8480169119dabc0e655 306 Gene3D G3DSA:2.60.200.30 160 270 2.3E-36 T 06-07-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 SMD11_RS25765 44970a162c81f8480169119dabc0e655 306 Gene3D G3DSA:3.40.50.10330 10 159 3.4E-31 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 SMD11_RS22005 0c6aa8016509a1b079d80d298a289647 552 Gene3D G3DSA:3.40.50.300 61 104 4.7E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22005 0c6aa8016509a1b079d80d298a289647 552 Gene3D G3DSA:3.40.50.300 173 256 4.7E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22005 0c6aa8016509a1b079d80d298a289647 552 SUPERFAMILY SSF52540 37 266 4.79E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22005 0c6aa8016509a1b079d80d298a289647 552 Pfam PF00350 Dynamin family 62 212 3.9E-9 T 06-07-2017 IPR022812 Dynamin superfamily SMD11_RS02060 ab4cf112f0f6c48f44476a65dc49cb64 244 Pfam PF13349 Putative adhesin 120 241 5.2E-8 T 06-07-2017 IPR025164 Putative adhesin SMD11_RS25580 3b3dc02356ff46735e5c58e860b0c504 432 Gene3D G3DSA:1.20.1250.20 245 423 5.3E-11 T 06-07-2017 SMD11_RS25580 3b3dc02356ff46735e5c58e860b0c504 432 Gene3D G3DSA:1.20.1250.20 45 230 1.0E-18 T 06-07-2017 SMD11_RS25580 3b3dc02356ff46735e5c58e860b0c504 432 Pfam PF07690 Major Facilitator Superfamily 61 359 6.4E-18 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS25580 3b3dc02356ff46735e5c58e860b0c504 432 SUPERFAMILY SSF103473 31 425 2.62E-43 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS31525 b32a24da27586df7151ad9a2986fa6af 218 Gene3D G3DSA:1.10.10.60 22 70 5.4E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS31525 b32a24da27586df7151ad9a2986fa6af 218 SUPERFAMILY SSF48498 89 206 4.45E-25 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS31525 b32a24da27586df7151ad9a2986fa6af 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 76 2.7E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS31525 b32a24da27586df7151ad9a2986fa6af 218 Pfam PF16859 Bacterial transcriptional repressor C-terminal 89 198 4.6E-30 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS31525 b32a24da27586df7151ad9a2986fa6af 218 SUPERFAMILY SSF46689 22 82 6.48E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS31525 b32a24da27586df7151ad9a2986fa6af 218 Gene3D G3DSA:1.10.357.10 72 205 1.3E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS00655 f76f1229a2b849b52e63521f9796b4de 245 SUPERFAMILY SSF46785 12 76 3.51E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00655 f76f1229a2b849b52e63521f9796b4de 245 Gene3D G3DSA:1.10.10.10 11 71 1.5E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00655 f76f1229a2b849b52e63521f9796b4de 245 SMART SM00346 10 96 0.0014 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS00655 f76f1229a2b849b52e63521f9796b4de 245 Pfam PF09339 IclR helix-turn-helix domain 12 59 4.9E-9 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS00655 f76f1229a2b849b52e63521f9796b4de 245 Gene3D G3DSA:3.30.450.40 83 237 1.1E-17 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS00655 f76f1229a2b849b52e63521f9796b4de 245 Pfam PF01614 Bacterial transcriptional regulator 136 221 1.1E-6 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal SMD11_RS00655 f76f1229a2b849b52e63521f9796b4de 245 SUPERFAMILY SSF55781 85 240 7.19E-17 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS23450 2d4ee13033f851caf570e0a5c623ac69 410 PRINTS PR00359 B-class P450 signature 148 164 3.2E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS23450 2d4ee13033f851caf570e0a5c623ac69 410 PRINTS PR00359 B-class P450 signature 207 229 3.2E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS23450 2d4ee13033f851caf570e0a5c623ac69 410 PRINTS PR00359 B-class P450 signature 165 180 3.2E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS23450 2d4ee13033f851caf570e0a5c623ac69 410 PRINTS PR00359 B-class P450 signature 302 329 3.2E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS23450 2d4ee13033f851caf570e0a5c623ac69 410 PRINTS PR00359 B-class P450 signature 352 361 3.2E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS23450 2d4ee13033f851caf570e0a5c623ac69 410 PRINTS PR00359 B-class P450 signature 285 296 3.2E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS23450 2d4ee13033f851caf570e0a5c623ac69 410 PRINTS PR00359 B-class P450 signature 330 345 3.2E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS23450 2d4ee13033f851caf570e0a5c623ac69 410 PRINTS PR00359 B-class P450 signature 361 372 3.2E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS23450 2d4ee13033f851caf570e0a5c623ac69 410 PRINTS PR00359 B-class P450 signature 102 113 3.2E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS23450 2d4ee13033f851caf570e0a5c623ac69 410 Gene3D G3DSA:1.10.630.10 7 409 1.6E-114 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS23450 2d4ee13033f851caf570e0a5c623ac69 410 Pfam PF00067 Cytochrome P450 288 378 4.8E-15 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS23450 2d4ee13033f851caf570e0a5c623ac69 410 SUPERFAMILY SSF48264 21 409 1.57E-83 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06330 afc7e4f805a73e3a6e14b9513009a5a9 216 Gene3D G3DSA:1.10.357.10 70 198 5.0E-39 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS06330 afc7e4f805a73e3a6e14b9513009a5a9 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 4.0E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS06330 afc7e4f805a73e3a6e14b9513009a5a9 216 Gene3D G3DSA:1.10.10.60 4 67 6.9E-24 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS06330 afc7e4f805a73e3a6e14b9513009a5a9 216 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 59 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD11_RS06330 afc7e4f805a73e3a6e14b9513009a5a9 216 SUPERFAMILY SSF48498 83 198 8.43E-28 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS06330 afc7e4f805a73e3a6e14b9513009a5a9 216 SUPERFAMILY SSF46689 3 87 5.64E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS18940 2e76fb9fc405bffe15dc3257230938bd 107 SMART SM00739 2 29 2.9E-4 T 06-07-2017 IPR005824 KOW SMD11_RS18940 2e76fb9fc405bffe15dc3257230938bd 107 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 06-07-2017 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18940 2e76fb9fc405bffe15dc3257230938bd 107 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 107 3.1E-35 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18940 2e76fb9fc405bffe15dc3257230938bd 107 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 107 2.9E-23 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18940 2e76fb9fc405bffe15dc3257230938bd 107 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 101 21.098 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18940 2e76fb9fc405bffe15dc3257230938bd 107 SUPERFAMILY SSF50104 1 105 4.14E-29 T 06-07-2017 IPR008991 Translation protein SH3-like domain SMD11_RS18940 2e76fb9fc405bffe15dc3257230938bd 107 Pfam PF00467 KOW motif 5 36 2.5E-6 T 06-07-2017 IPR005824 KOW SMD11_RS18940 2e76fb9fc405bffe15dc3257230938bd 107 Gene3D G3DSA:2.30.30.30 1 95 2.1E-25 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 SMD11_RS31325 c449f22d08184ce7f055c8293d636e96 773 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 10 768 34.865 T 06-07-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD11_RS31325 c449f22d08184ce7f055c8293d636e96 773 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 441 763 4.7E-141 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD11_RS31325 c449f22d08184ce7f055c8293d636e96 773 SUPERFAMILY SSF51726 12 404 1.07E-99 T 06-07-2017 SMD11_RS31325 c449f22d08184ce7f055c8293d636e96 773 SUPERFAMILY SSF51726 406 766 2.49E-113 T 06-07-2017 SMD11_RS31325 c449f22d08184ce7f055c8293d636e96 773 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 16 767 0.0 T 06-07-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD11_RS31325 c449f22d08184ce7f055c8293d636e96 773 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 13 323 2.9E-114 T 06-07-2017 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD11_RS31325 c449f22d08184ce7f055c8293d636e96 773 PIRSF PIRSF000382 9 773 0.0 T 06-07-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD11_RS31325 c449f22d08184ce7f055c8293d636e96 773 Gene3D G3DSA:3.20.20.210 12 399 5.3E-139 T 06-07-2017 SMD11_RS31325 c449f22d08184ce7f055c8293d636e96 773 Gene3D G3DSA:3.20.20.210 403 768 5.4E-127 T 06-07-2017 SMD11_RS09345 15bf77f48a0cc1f0e94166f1c12bb210 465 SUPERFAMILY SSF51905 11 129 2.59E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS09345 15bf77f48a0cc1f0e94166f1c12bb210 465 SUPERFAMILY SSF51905 185 315 2.59E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS09345 15bf77f48a0cc1f0e94166f1c12bb210 465 Gene3D G3DSA:3.30.9.10 130 182 1.6E-5 T 06-07-2017 SMD11_RS09345 15bf77f48a0cc1f0e94166f1c12bb210 465 Gene3D G3DSA:3.30.9.10 260 360 1.6E-5 T 06-07-2017 SMD11_RS09345 15bf77f48a0cc1f0e94166f1c12bb210 465 Gene3D G3DSA:3.50.50.60 27 126 1.9E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS09345 15bf77f48a0cc1f0e94166f1c12bb210 465 Gene3D G3DSA:3.50.50.60 363 415 1.9E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS09345 15bf77f48a0cc1f0e94166f1c12bb210 465 Gene3D G3DSA:3.50.50.60 183 259 1.9E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS09345 15bf77f48a0cc1f0e94166f1c12bb210 465 Pfam PF01266 FAD dependent oxidoreductase 37 398 9.3E-46 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 SUPERFAMILY SSF47323 655 892 1.44E-49 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 23 628 1.8E-167 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 519 532 5.3E-26 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 392 407 5.3E-26 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 229 252 5.3E-26 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 46 57 5.3E-26 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 559 568 5.3E-26 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 8 1046 13.781 T 06-07-2017 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 Gene3D G3DSA:1.10.730.10 646 823 3.5E-47 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 Gene3D G3DSA:3.40.50.620 10 199 2.5E-135 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 Gene3D G3DSA:3.40.50.620 397 635 2.5E-135 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 10 838 1.2E-270 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 SUPERFAMILY SSF50677 206 394 2.62E-45 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 SUPERFAMILY SSF52374 394 648 2.73E-122 T 06-07-2017 SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 SUPERFAMILY SSF52374 10 203 2.73E-122 T 06-07-2017 SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 Pfam PF08264 Anticodon-binding domain of tRNA 687 832 1.5E-30 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SMD11_RS24560 5de8da91d64711f0d3b0201f04a674f4 1048 Gene3D G3DSA:3.90.740.10 208 380 1.8E-50 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SMD11_RS33095 130f793b6505e840e3e2b037838c2015 1063 Gene3D G3DSA:2.130.10.10 575 676 7.0E-5 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS33095 130f793b6505e840e3e2b037838c2015 1063 Pfam PF07676 WD40-like Beta Propeller Repeat 160 196 8.8E-8 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS33095 130f793b6505e840e3e2b037838c2015 1063 Pfam PF07676 WD40-like Beta Propeller Repeat 502 527 1.3E-5 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS33095 130f793b6505e840e3e2b037838c2015 1063 Pfam PF07676 WD40-like Beta Propeller Repeat 446 468 1.5E-5 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS33095 130f793b6505e840e3e2b037838c2015 1063 SUPERFAMILY SSF82171 113 230 5.89E-31 T 06-07-2017 SMD11_RS33095 130f793b6505e840e3e2b037838c2015 1063 SUPERFAMILY SSF82171 263 308 5.89E-31 T 06-07-2017 SMD11_RS33095 130f793b6505e840e3e2b037838c2015 1063 SUPERFAMILY SSF82171 621 670 5.89E-31 T 06-07-2017 SMD11_RS33095 130f793b6505e840e3e2b037838c2015 1063 SUPERFAMILY SSF82171 400 586 5.89E-31 T 06-07-2017 SMD11_RS33095 130f793b6505e840e3e2b037838c2015 1063 Gene3D G3DSA:2.130.10.10 105 274 2.1E-56 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS33095 130f793b6505e840e3e2b037838c2015 1063 Gene3D G3DSA:2.130.10.10 401 574 2.1E-56 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS27125 cb38f8034a506ba14a6a3c590c54acf0 286 SUPERFAMILY SSF88713 84 284 1.58E-38 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS27125 cb38f8034a506ba14a6a3c590c54acf0 286 Gene3D G3DSA:3.20.20.370 88 285 5.8E-37 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS27125 cb38f8034a506ba14a6a3c590c54acf0 286 Pfam PF01522 Polysaccharide deacetylase 95 216 5.6E-16 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS13395 29f645ba93e4d6c511d0fcd7d46ad903 257 SUPERFAMILY SSF46785 9 87 5.9E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13395 29f645ba93e4d6c511d0fcd7d46ad903 257 SMART SM00345 18 77 4.2E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS13395 29f645ba93e4d6c511d0fcd7d46ad903 257 SMART SM00866 108 249 4.6E-18 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS13395 29f645ba93e4d6c511d0fcd7d46ad903 257 Gene3D G3DSA:3.40.1410.10 80 252 1.1E-35 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS13395 29f645ba93e4d6c511d0fcd7d46ad903 257 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 5.6E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS13395 29f645ba93e4d6c511d0fcd7d46ad903 257 Pfam PF07702 UTRA domain 110 245 1.0E-21 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS13395 29f645ba93e4d6c511d0fcd7d46ad903 257 Gene3D G3DSA:1.10.10.10 9 79 6.6E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13395 29f645ba93e4d6c511d0fcd7d46ad903 257 SUPERFAMILY SSF64288 100 254 5.42E-30 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS26555 e746b4409630485d07b11624d787b680 125 Gene3D G3DSA:3.10.50.40 14 123 8.6E-40 T 06-07-2017 SMD11_RS26555 e746b4409630485d07b11624d787b680 125 SUPERFAMILY SSF54534 16 123 8.64E-38 T 06-07-2017 SMD11_RS26555 e746b4409630485d07b11624d787b680 125 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 30 120 2.4E-29 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 SMD11_RS07210 eb3fb3d79a0280f3fa5dfa5fe52090aa 302 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 32 256 4.0E-45 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 SMD11_RS07210 eb3fb3d79a0280f3fa5dfa5fe52090aa 302 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 11 302 2.6E-136 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMD11_RS07210 eb3fb3d79a0280f3fa5dfa5fe52090aa 302 SUPERFAMILY SSF52402 8 209 4.19E-61 T 06-07-2017 SMD11_RS07210 eb3fb3d79a0280f3fa5dfa5fe52090aa 302 PIRSF PIRSF002936 2 302 1.2E-135 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMD11_RS07210 eb3fb3d79a0280f3fa5dfa5fe52090aa 302 Gene3D G3DSA:3.40.50.620 9 210 5.3E-50 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS07210 eb3fb3d79a0280f3fa5dfa5fe52090aa 302 Gene3D G3DSA:3.40.50.620 243 251 5.3E-50 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 SMART SM00766 495 621 5.1E-11 T 06-07-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 Pfam PF13662 Toprim domain 263 336 2.8E-16 T 06-07-2017 IPR006171 Toprim domain SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 Pfam PF01807 CHC2 zinc finger 7 101 1.6E-31 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 254 3.8E-39 T 06-07-2017 IPR013264 DNA primase, catalytic core, N-terminal SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 Gene3D G3DSA:3.40.1360.10 244 371 5.8E-41 T 06-07-2017 SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 SUPERFAMILY SSF57783 4 102 4.59E-31 T 06-07-2017 SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 Hamap MF_00974 DNA primase [dnaG]. 4 626 26.532 T 06-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 Pfam PF10410 DnaB-helicase binding domain of primase 374 427 1.9E-14 T 06-07-2017 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 Pfam PF08278 DNA primase DnaG DnaB-binding 496 610 1.4E-12 T 06-07-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 PIRSF PIRSF002811 2 632 1.2E-168 T 06-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 Gene3D G3DSA:1.20.50.20 373 430 1.5E-10 T 06-07-2017 SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 SMART SM00493 262 338 7.2E-15 T 06-07-2017 IPR006171 Toprim domain SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 Gene3D G3DSA:3.90.980.10 117 242 1.4E-41 T 06-07-2017 IPR013264 DNA primase, catalytic core, N-terminal SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 SUPERFAMILY SSF56731 117 429 3.14E-97 T 06-07-2017 SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 Gene3D G3DSA:3.90.580.10 3 102 4.2E-35 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 TIGRFAM TIGR01391 dnaG: DNA primase 5 421 9.5E-121 T 06-07-2017 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 SMD11_RS23030 f4d665061201256ab1b5b3da51029ac9 642 SMART SM00400 37 91 8.3E-32 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SMD11_RS13145 98f0e82e03263cf25ab80b06c9cb6b8c 247 Gene3D G3DSA:3.20.20.60 3 221 1.9E-56 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS13145 98f0e82e03263cf25ab80b06c9cb6b8c 247 SUPERFAMILY SSF51621 4 240 1.7E-48 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS13145 98f0e82e03263cf25ab80b06c9cb6b8c 247 Pfam PF13714 Phosphoenolpyruvate phosphomutase 8 237 3.6E-62 T 06-07-2017 SMD11_RS09640 6777d8f2da61892484cb2dae2b8e442c 439 SUPERFAMILY SSF111352 2 375 5.1E-123 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 SMD11_RS09640 6777d8f2da61892484cb2dae2b8e442c 439 Pfam PF00909 Ammonium Transporter Family 7 395 6.8E-119 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 SMD11_RS09640 6777d8f2da61892484cb2dae2b8e442c 439 ProSitePatterns PS01219 Ammonium transporters signature. 161 186 - T 06-07-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 SMD11_RS09640 6777d8f2da61892484cb2dae2b8e442c 439 Gene3D G3DSA:1.10.3430.10 2 375 3.2E-133 T 06-07-2017 IPR029020 Ammonium/urea transporter SMD11_RS09640 6777d8f2da61892484cb2dae2b8e442c 439 TIGRFAM TIGR00836 amt: ammonium transporter 5 395 5.6E-131 T 06-07-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 SMD11_RS12170 08206e864690f049be675fb143dc65ba 559 Gene3D G3DSA:3.20.130.10 364 542 5.9E-72 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 SMD11_RS12170 08206e864690f049be675fb143dc65ba 559 Pfam PF05683 Fumarase C-terminus 333 542 6.7E-91 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 SMD11_RS12170 08206e864690f049be675fb143dc65ba 559 PIRSF PIRSF001394 31 558 5.9E-224 T 06-07-2017 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 SMD11_RS12170 08206e864690f049be675fb143dc65ba 559 SUPERFAMILY SSF117457 368 542 1.57E-60 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 SMD11_RS12170 08206e864690f049be675fb143dc65ba 559 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 54 328 1.0E-33 T 06-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 SMD11_RS12170 08206e864690f049be675fb143dc65ba 559 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 380 542 2.8E-57 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 SMD11_RS12170 08206e864690f049be675fb143dc65ba 559 ProSitePatterns PS00163 Fumarate lyases signature. 463 472 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 SMD11_RS12170 08206e864690f049be675fb143dc65ba 559 Pfam PF05681 Fumarate hydratase (Fumerase) 50 327 4.1E-89 T 06-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 SMD11_RS09290 31229c1ea4796900cb8d4853defacf20 385 SUPERFAMILY SSF56014 275 359 8.5E-11 T 06-07-2017 SMD11_RS09290 31229c1ea4796900cb8d4853defacf20 385 PIRSF PIRSF004640 11 373 1.6E-145 T 06-07-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD11_RS09290 31229c1ea4796900cb8d4853defacf20 385 SUPERFAMILY SSF51717 45 219 2.28E-9 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS09290 31229c1ea4796900cb8d4853defacf20 385 Pfam PF04551 GcpE protein 22 361 5.4E-134 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD11_RS09290 31229c1ea4796900cb8d4853defacf20 385 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 3.9E-129 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD11_RS09290 31229c1ea4796900cb8d4853defacf20 385 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.739 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD11_RS04930 b6698aba5b296c48724a6b03f7b9728b 412 Gene3D G3DSA:1.10.540.10 12 108 6.9E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS04930 b6698aba5b296c48724a6b03f7b9728b 412 SUPERFAMILY SSF56645 26 238 9.29E-38 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS04930 b6698aba5b296c48724a6b03f7b9728b 412 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 144 230 1.1E-11 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS04930 b6698aba5b296c48724a6b03f7b9728b 412 Gene3D G3DSA:1.20.140.10 232 397 3.2E-24 T 06-07-2017 SMD11_RS04930 b6698aba5b296c48724a6b03f7b9728b 412 SUPERFAMILY SSF47203 264 394 1.77E-14 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS04930 b6698aba5b296c48724a6b03f7b9728b 412 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 263 390 1.1E-11 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain SMD11_RS04930 b6698aba5b296c48724a6b03f7b9728b 412 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 31 115 4.5E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS04930 b6698aba5b296c48724a6b03f7b9728b 412 Gene3D G3DSA:2.40.110.10 145 231 1.8E-21 T 06-07-2017 SMD11_RS00110 93d6d06727df90e14b481432d3788f8e 80 SUPERFAMILY SSF53474 3 51 8.62E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS00110 93d6d06727df90e14b481432d3788f8e 80 Gene3D G3DSA:3.40.50.1820 5 62 1.2E-4 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS26620 80c05e476d8d4cf024da84541d916482 603 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 341 589 9.8E-64 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SMD11_RS26620 80c05e476d8d4cf024da84541d916482 603 SUPERFAMILY SSF161098 82 265 7.06E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS26620 80c05e476d8d4cf024da84541d916482 603 Gene3D G3DSA:1.10.3720.10 79 266 2.5E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS26620 80c05e476d8d4cf024da84541d916482 603 SUPERFAMILY SSF53850 338 597 1.51E-69 T 06-07-2017 SMD11_RS26620 80c05e476d8d4cf024da84541d916482 603 Gene3D G3DSA:3.40.190.100 426 541 1.3E-37 T 06-07-2017 SMD11_RS26620 80c05e476d8d4cf024da84541d916482 603 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 262 2.2E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS26620 80c05e476d8d4cf024da84541d916482 603 Gene3D G3DSA:3.40.190.10 338 422 2.3E-55 T 06-07-2017 SMD11_RS26620 80c05e476d8d4cf024da84541d916482 603 Gene3D G3DSA:3.40.190.10 542 598 2.3E-55 T 06-07-2017 SMD11_RS04190 654c9ed694adae26081cac082dbdcd07 379 Gene3D G3DSA:3.40.50.20 83 173 3.8E-17 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS04190 654c9ed694adae26081cac082dbdcd07 379 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 84 340 5.3E-54 T 06-07-2017 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 SMD11_RS04190 654c9ed694adae26081cac082dbdcd07 379 Gene3D G3DSA:3.30.470.20 244 334 3.8E-19 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS04190 654c9ed694adae26081cac082dbdcd07 379 Pfam PF08443 RimK-like ATP-grasp domain 169 339 1.4E-26 T 06-07-2017 IPR013651 ATP-grasp fold, RimK-type SMD11_RS04190 654c9ed694adae26081cac082dbdcd07 379 SUPERFAMILY SSF56059 170 343 2.12E-28 T 06-07-2017 SMD11_RS04190 654c9ed694adae26081cac082dbdcd07 379 Gene3D G3DSA:3.30.1490.20 174 243 3.4E-5 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS06975 9e00b2dc6f0a5035eefecdf0a4209d38 278 Pfam PF01261 Xylose isomerase-like TIM barrel 26 226 2.0E-27 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS06975 9e00b2dc6f0a5035eefecdf0a4209d38 278 PIRSF PIRSF006241 4 277 5.7E-77 T 06-07-2017 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 SMD11_RS06975 9e00b2dc6f0a5035eefecdf0a4209d38 278 SUPERFAMILY SSF51658 7 272 1.8E-60 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS06975 9e00b2dc6f0a5035eefecdf0a4209d38 278 Gene3D G3DSA:3.20.20.150 6 272 3.2E-71 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS02400 9de6308a71374dc62461b7fc7d253b9c 398 SUPERFAMILY SSF103473 3 366 2.75E-34 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS02400 9de6308a71374dc62461b7fc7d253b9c 398 Gene3D G3DSA:1.20.1250.20 2 167 9.1E-12 T 06-07-2017 SMD11_RS02400 9de6308a71374dc62461b7fc7d253b9c 398 Gene3D G3DSA:1.20.1250.20 190 358 2.4E-12 T 06-07-2017 SMD11_RS02400 9de6308a71374dc62461b7fc7d253b9c 398 Pfam PF07690 Major Facilitator Superfamily 3 325 1.8E-16 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS22095 0a5b03254e1eeb1ce0667627fb59300f 310 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 10 309 3.9E-15 T 06-07-2017 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 SMD11_RS22095 0a5b03254e1eeb1ce0667627fb59300f 310 SUPERFAMILY SSF53067 124 310 9.5E-32 T 06-07-2017 SMD11_RS22095 0a5b03254e1eeb1ce0667627fb59300f 310 SUPERFAMILY SSF53067 8 115 5.96E-13 T 06-07-2017 SMD11_RS21215 ddf80b5db808ecb316d33248b3493c6e 501 ProSitePatterns PS00218 Amino acid permeases signature. 62 92 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD11_RS21215 ddf80b5db808ecb316d33248b3493c6e 501 PIRSF PIRSF006060 8 496 3.7E-70 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS21215 ddf80b5db808ecb316d33248b3493c6e 501 Pfam PF00324 Amino acid permease 38 474 1.5E-114 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMD11_RS03980 2816554542ad3b59b070d811e85768b1 393 SUPERFAMILY SSF51905 2 170 6.02E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03980 2816554542ad3b59b070d811e85768b1 393 SUPERFAMILY SSF51905 271 352 6.02E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03980 2816554542ad3b59b070d811e85768b1 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 8.4E-17 T 06-07-2017 SMD11_RS03980 2816554542ad3b59b070d811e85768b1 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 8.4E-17 T 06-07-2017 SMD11_RS03980 2816554542ad3b59b070d811e85768b1 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 8.4E-17 T 06-07-2017 SMD11_RS03980 2816554542ad3b59b070d811e85768b1 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 8.4E-17 T 06-07-2017 SMD11_RS03980 2816554542ad3b59b070d811e85768b1 393 Gene3D G3DSA:3.50.50.60 272 349 4.4E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03980 2816554542ad3b59b070d811e85768b1 393 Gene3D G3DSA:3.50.50.60 2 175 4.4E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03980 2816554542ad3b59b070d811e85768b1 393 Pfam PF01494 FAD binding domain 2 345 2.6E-16 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS02050 313ff6a352dc3a6c35459a284a92c4c3 419 Pfam PF06889 Protein of unknown function (DUF1266) 212 415 3.9E-44 T 06-07-2017 IPR009677 Protein of unknown function DUF1266 SMD11_RS03940 806f9994dc4fbe81f44ae5a071c73b38 441 Pfam PF12867 DinB superfamily 18 149 1.3E-27 T 06-07-2017 IPR024775 DinB-like domain SMD11_RS03940 806f9994dc4fbe81f44ae5a071c73b38 441 Pfam PF03781 Sulfatase-modifying factor enzyme 1 178 436 7.9E-62 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 SMD11_RS03940 806f9994dc4fbe81f44ae5a071c73b38 441 Gene3D G3DSA:3.90.1580.10 174 439 7.6E-75 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 SMD11_RS03940 806f9994dc4fbe81f44ae5a071c73b38 441 SUPERFAMILY SSF56436 181 439 7.91E-75 T 06-07-2017 IPR016187 C-type lectin fold SMD11_RS03940 806f9994dc4fbe81f44ae5a071c73b38 441 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 16 435 1.6E-134 T 06-07-2017 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 SMD11_RS03940 806f9994dc4fbe81f44ae5a071c73b38 441 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 438 52.214 T 06-07-2017 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 SMD11_RS03940 806f9994dc4fbe81f44ae5a071c73b38 441 SUPERFAMILY SSF109854 8 145 1.13E-20 T 06-07-2017 SMD11_RS03940 806f9994dc4fbe81f44ae5a071c73b38 441 Gene3D G3DSA:1.20.120.450 12 123 1.4E-7 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase SMD11_RS18180 c42b0d390bc2c26a506cfa05b06dfb31 361 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 266 5.5E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18180 c42b0d390bc2c26a506cfa05b06dfb31 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.4E-14 T 06-07-2017 SMD11_RS18180 c42b0d390bc2c26a506cfa05b06dfb31 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 1.4E-14 T 06-07-2017 SMD11_RS18180 c42b0d390bc2c26a506cfa05b06dfb31 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 208 224 1.4E-14 T 06-07-2017 SMD11_RS18180 c42b0d390bc2c26a506cfa05b06dfb31 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 258 1.4E-14 T 06-07-2017 SMD11_RS18180 c42b0d390bc2c26a506cfa05b06dfb31 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 133 157 4.8E-10 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS18180 c42b0d390bc2c26a506cfa05b06dfb31 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 4.8E-10 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS18180 c42b0d390bc2c26a506cfa05b06dfb31 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 99 107 4.8E-10 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS18180 c42b0d390bc2c26a506cfa05b06dfb31 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 246 264 4.8E-10 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS18180 c42b0d390bc2c26a506cfa05b06dfb31 361 SUPERFAMILY SSF51905 5 283 1.23E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18180 c42b0d390bc2c26a506cfa05b06dfb31 361 Gene3D G3DSA:3.50.50.60 101 281 9.8E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18180 c42b0d390bc2c26a506cfa05b06dfb31 361 Gene3D G3DSA:3.50.50.60 9 100 3.0E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS00435 961b86795c17505df3f0cf7793da9abe 634 Gene3D G3DSA:3.50.50.60 3 190 5.7E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS00435 961b86795c17505df3f0cf7793da9abe 634 SUPERFAMILY SSF51905 3 74 1.62E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS00435 961b86795c17505df3f0cf7793da9abe 634 SUPERFAMILY SSF51905 121 242 1.62E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS00435 961b86795c17505df3f0cf7793da9abe 634 Pfam PF13454 FAD-NAD(P)-binding 6 183 5.6E-43 T 06-07-2017 SMD11_RS24415 a69ff7613dffd1cfcb8959480ec6b5b7 219 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 13 207 2.2E-56 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SMD11_RS24415 a69ff7613dffd1cfcb8959480ec6b5b7 219 Gene3D G3DSA:3.20.20.70 6 213 5.5E-68 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS24415 a69ff7613dffd1cfcb8959480ec6b5b7 219 SUPERFAMILY SSF51391 8 210 7.85E-57 T 06-07-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SMD11_RS24415 a69ff7613dffd1cfcb8959480ec6b5b7 219 Pfam PF02581 Thiamine monophosphate synthase/TENI 14 195 6.4E-49 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SMD11_RS24415 a69ff7613dffd1cfcb8959480ec6b5b7 219 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 11 213 23.362 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SMD11_RS16610 048d16e7da7296049d66b5c7c2155124 169 Pfam PF00293 NUDIX domain 14 127 3.1E-20 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS16610 048d16e7da7296049d66b5c7c2155124 169 PRINTS PR00502 NUDIX hydrolase family signature 39 53 2.7E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS16610 048d16e7da7296049d66b5c7c2155124 169 PRINTS PR00502 NUDIX hydrolase family signature 53 68 2.7E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS16610 048d16e7da7296049d66b5c7c2155124 169 ProSitePatterns PS00893 Nudix box signature. 44 65 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD11_RS16610 048d16e7da7296049d66b5c7c2155124 169 SUPERFAMILY SSF55811 7 139 1.11E-27 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS16610 048d16e7da7296049d66b5c7c2155124 169 Gene3D G3DSA:3.90.79.10 11 143 2.0E-27 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS13430 eb38e462c46f4cfb4c6c68582882df69 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 123 3.7E-16 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS13430 eb38e462c46f4cfb4c6c68582882df69 133 Gene3D G3DSA:3.10.180.10 2 128 1.3E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS13430 eb38e462c46f4cfb4c6c68582882df69 133 SUPERFAMILY SSF54593 3 129 6.18E-28 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS03705 929f3d7af9a1ba87e9d1b313cf4eab5e 1124 Gene3D G3DSA:3.30.930.10 776 1119 1.0E-98 T 06-07-2017 SMD11_RS03705 929f3d7af9a1ba87e9d1b313cf4eab5e 1124 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 635 1122 1.3E-139 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD11_RS03705 929f3d7af9a1ba87e9d1b313cf4eab5e 1124 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 40 246 2.8E-58 T 06-07-2017 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 SMD11_RS03705 929f3d7af9a1ba87e9d1b313cf4eab5e 1124 SUPERFAMILY SSF55681 779 1122 1.82E-98 T 06-07-2017 SMD11_RS03705 929f3d7af9a1ba87e9d1b313cf4eab5e 1124 PRINTS PR00982 Lysyl-tRNA synthetase signature 816 826 4.1E-29 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD11_RS03705 929f3d7af9a1ba87e9d1b313cf4eab5e 1124 PRINTS PR00982 Lysyl-tRNA synthetase signature 832 848 4.1E-29 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD11_RS03705 929f3d7af9a1ba87e9d1b313cf4eab5e 1124 PRINTS PR00982 Lysyl-tRNA synthetase signature 879 896 4.1E-29 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD11_RS03705 929f3d7af9a1ba87e9d1b313cf4eab5e 1124 PRINTS PR00982 Lysyl-tRNA synthetase signature 861 874 4.1E-29 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD11_RS03705 929f3d7af9a1ba87e9d1b313cf4eab5e 1124 PRINTS PR00982 Lysyl-tRNA synthetase signature 1007 1023 4.1E-29 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD11_RS03705 929f3d7af9a1ba87e9d1b313cf4eab5e 1124 SUPERFAMILY SSF50249 633 772 4.16E-35 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS03705 929f3d7af9a1ba87e9d1b313cf4eab5e 1124 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 264 563 1.4E-105 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal SMD11_RS03705 929f3d7af9a1ba87e9d1b313cf4eab5e 1124 Pfam PF01336 OB-fold nucleic acid binding domain 685 759 2.6E-14 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SMD11_RS03705 929f3d7af9a1ba87e9d1b313cf4eab5e 1124 Pfam PF00152 tRNA synthetases class II (D, K and N) 781 1121 2.6E-68 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS03705 929f3d7af9a1ba87e9d1b313cf4eab5e 1124 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 639 1124 35.607 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SMD11_RS03705 929f3d7af9a1ba87e9d1b313cf4eab5e 1124 Gene3D G3DSA:2.40.50.140 634 772 9.2E-40 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS23130 3a278c3e5c80b718dd964f0ca75fe437 428 Gene3D G3DSA:3.40.630.20 168 386 3.0E-10 T 06-07-2017 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like SMD11_RS23130 3a278c3e5c80b718dd964f0ca75fe437 428 SUPERFAMILY SSF53182 344 390 4.19E-24 T 06-07-2017 SMD11_RS23130 3a278c3e5c80b718dd964f0ca75fe437 428 SUPERFAMILY SSF53182 168 316 4.19E-24 T 06-07-2017 SMD11_RS33065 21c962d5b0ff0b4fe4997b76dabc92e0 514 Gene3D G3DSA:2.30.38.10 336 409 6.6E-29 T 06-07-2017 SMD11_RS33065 21c962d5b0ff0b4fe4997b76dabc92e0 514 Gene3D G3DSA:3.40.50.980 24 187 3.5E-18 T 06-07-2017 SMD11_RS33065 21c962d5b0ff0b4fe4997b76dabc92e0 514 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS33065 21c962d5b0ff0b4fe4997b76dabc92e0 514 SUPERFAMILY SSF56801 17 513 1.7E-118 T 06-07-2017 SMD11_RS33065 21c962d5b0ff0b4fe4997b76dabc92e0 514 Gene3D G3DSA:3.30.300.30 413 511 3.5E-24 T 06-07-2017 SMD11_RS33065 21c962d5b0ff0b4fe4997b76dabc92e0 514 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 502 1.0E-14 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS33065 21c962d5b0ff0b4fe4997b76dabc92e0 514 Gene3D G3DSA:3.40.50.980 188 320 1.7E-27 T 06-07-2017 SMD11_RS33065 21c962d5b0ff0b4fe4997b76dabc92e0 514 Pfam PF00501 AMP-binding enzyme 25 418 3.7E-77 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS10395 26c04783d6ee97c36d2a0f6fd43a3b58 502 SUPERFAMILY SSF56112 200 486 2.24E-22 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS10060 8a066be7305f807aea12429c22c7b4c5 333 SUPERFAMILY SSF51735 4 184 7.76E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10060 8a066be7305f807aea12429c22c7b4c5 333 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 328 1.8E-133 T 06-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMD11_RS10060 8a066be7305f807aea12429c22c7b4c5 333 Gene3D G3DSA:1.10.1040.10 31 327 2.5E-112 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS10060 8a066be7305f807aea12429c22c7b4c5 333 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 3 330 44.725 T 06-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMD11_RS10060 8a066be7305f807aea12429c22c7b4c5 333 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 328 1.5E-64 T 06-07-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMD11_RS10060 8a066be7305f807aea12429c22c7b4c5 333 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 179 5.1E-76 T 06-07-2017 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 SMD11_RS10060 8a066be7305f807aea12429c22c7b4c5 333 SUPERFAMILY SSF48179 185 330 3.06E-68 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 Gene3D G3DSA:3.40.50.620 181 387 1.5E-79 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 Gene3D G3DSA:3.40.50.620 4 141 1.5E-79 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 Gene3D G3DSA:2.20.28.20 142 173 4.2E-18 T 06-07-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 SUPERFAMILY SSF57770 139 172 1.96E-11 T 06-07-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 Pfam PF09334 tRNA synthetases class I (M) 4 405 1.0E-151 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 SUPERFAMILY SSF52374 4 138 3.75E-82 T 06-07-2017 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 SUPERFAMILY SSF52374 174 392 3.75E-82 T 06-07-2017 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 Gene3D G3DSA:1.10.730.10 388 553 4.9E-41 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 Pfam PF08264 Anticodon-binding domain of tRNA 431 510 3.8E-8 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 8.6E-28 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 257 268 8.6E-28 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 8.6E-28 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 298 313 8.6E-28 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 8.6E-28 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 392 403 8.6E-28 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 564 37.304 T 06-07-2017 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 534 1.1E-146 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD11_RS17340 ff449c7792aa6460e167f4b176952823 572 SUPERFAMILY SSF47323 393 553 5.23E-35 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS15515 8760f8b5a40c0060b007998e0b18562d 297 Gene3D G3DSA:3.90.79.10 25 217 9.6E-18 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS15515 8760f8b5a40c0060b007998e0b18562d 297 SUPERFAMILY SSF55811 28 76 5.54E-15 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS15515 8760f8b5a40c0060b007998e0b18562d 297 SUPERFAMILY SSF55811 162 231 5.54E-15 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS15515 8760f8b5a40c0060b007998e0b18562d 297 SUPERFAMILY SSF55811 103 117 5.54E-15 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS10075 6c5caefe302c3e05d7a296a5cfdcd36b 992 Gene3D G3DSA:3.30.450.20 343 462 6.5E-18 T 06-07-2017 SMD11_RS10075 6c5caefe302c3e05d7a296a5cfdcd36b 992 SMART SM00267 462 640 3.4E-55 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS10075 6c5caefe302c3e05d7a296a5cfdcd36b 992 SUPERFAMILY SSF141868 657 905 2.88E-48 T 06-07-2017 IPR001633 EAL domain SMD11_RS10075 6c5caefe302c3e05d7a296a5cfdcd36b 992 Pfam PF00563 EAL domain 657 896 2.2E-45 T 06-07-2017 IPR001633 EAL domain SMD11_RS10075 6c5caefe302c3e05d7a296a5cfdcd36b 992 SMART SM00052 650 901 1.3E-35 T 06-07-2017 IPR001633 EAL domain SMD11_RS10075 6c5caefe302c3e05d7a296a5cfdcd36b 992 SMART SM00091 350 416 1.5E-9 T 06-07-2017 IPR000014 PAS domain SMD11_RS10075 6c5caefe302c3e05d7a296a5cfdcd36b 992 Gene3D G3DSA:3.30.70.270 474 648 6.3E-54 T 06-07-2017 SMD11_RS10075 6c5caefe302c3e05d7a296a5cfdcd36b 992 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 469 639 3.0E-41 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS10075 6c5caefe302c3e05d7a296a5cfdcd36b 992 SUPERFAMILY SSF55785 342 460 3.63E-17 T 06-07-2017 IPR000014 PAS domain SMD11_RS10075 6c5caefe302c3e05d7a296a5cfdcd36b 992 Gene3D G3DSA:3.20.20.450 653 908 4.8E-68 T 06-07-2017 IPR001633 EAL domain SMD11_RS10075 6c5caefe302c3e05d7a296a5cfdcd36b 992 Pfam PF00990 Diguanylate cyclase, GGDEF domain 473 635 2.9E-40 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS10075 6c5caefe302c3e05d7a296a5cfdcd36b 992 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 347 469 1.9E-13 T 06-07-2017 IPR000014 PAS domain SMD11_RS10075 6c5caefe302c3e05d7a296a5cfdcd36b 992 Pfam PF08448 PAS fold 359 464 1.5E-8 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS10075 6c5caefe302c3e05d7a296a5cfdcd36b 992 SUPERFAMILY SSF55073 478 641 1.26E-42 T 06-07-2017 IPR029787 Nucleotide cyclase SMD11_RS15720 ec2456729cb5ebb2b1ce19e1b48dfe83 546 Pfam PF07730 Histidine kinase 347 409 4.8E-12 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS15720 ec2456729cb5ebb2b1ce19e1b48dfe83 546 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 460 545 1.6E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS15720 ec2456729cb5ebb2b1ce19e1b48dfe83 546 Gene3D G3DSA:3.30.450.40 3 161 1.5E-30 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS15720 ec2456729cb5ebb2b1ce19e1b48dfe83 546 SUPERFAMILY SSF55781 166 354 3.05E-24 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS15720 ec2456729cb5ebb2b1ce19e1b48dfe83 546 Gene3D G3DSA:3.30.565.10 454 544 6.6E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS15720 ec2456729cb5ebb2b1ce19e1b48dfe83 546 Pfam PF13185 GAF domain 16 154 1.3E-18 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS15720 ec2456729cb5ebb2b1ce19e1b48dfe83 546 Pfam PF13185 GAF domain 185 330 1.7E-12 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS15720 ec2456729cb5ebb2b1ce19e1b48dfe83 546 SUPERFAMILY SSF55874 450 544 9.31E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS15720 ec2456729cb5ebb2b1ce19e1b48dfe83 546 SMART SM00065 16 163 5.9E-16 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS15720 ec2456729cb5ebb2b1ce19e1b48dfe83 546 SMART SM00065 184 339 1.2E-4 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS15720 ec2456729cb5ebb2b1ce19e1b48dfe83 546 Gene3D G3DSA:3.30.450.40 162 341 2.3E-25 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS15720 ec2456729cb5ebb2b1ce19e1b48dfe83 546 SMART SM00387 452 546 6.1E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS15720 ec2456729cb5ebb2b1ce19e1b48dfe83 546 SUPERFAMILY SSF55781 3 181 1.72E-38 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 Gene3D G3DSA:3.40.50.1440 11 211 9.9E-91 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 06-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 SUPERFAMILY SSF55307 201 315 6.18E-44 T 06-07-2017 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 PRINTS PR00423 Cell division protein FtsZ signature 95 115 1.6E-51 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 PRINTS PR00423 Cell division protein FtsZ signature 209 230 1.6E-51 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 PRINTS PR00423 Cell division protein FtsZ signature 123 144 1.6E-51 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 PRINTS PR00423 Cell division protein FtsZ signature 186 208 1.6E-51 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 Pfam PF12327 FtsZ family, C-terminal domain 219 313 4.7E-35 T 06-07-2017 IPR024757 Cell division protein FtsZ, C-terminal SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 SUPERFAMILY SSF52490 9 205 1.3E-66 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 06-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 170 5.6E-37 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 Gene3D G3DSA:3.30.1330.20 212 314 3.6E-49 T 06-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 339 38.7 T 06-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 SMART SM00864 10 202 7.1E-108 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 SMART SM00865 204 321 8.9E-57 T 06-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 SMD11_RS24530 3047d1f889197c7afc3a3da68837617a 412 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 314 8.7E-127 T 06-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 SMD11_RS09960 a26f6f355e0808cb85a77c4ef7255a21 346 SMART SM01329 6 340 3.5E-167 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMD11_RS09960 a26f6f355e0808cb85a77c4ef7255a21 346 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 5 344 60.121 T 06-07-2017 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 SMD11_RS09960 a26f6f355e0808cb85a77c4ef7255a21 346 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 239 258 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 SMD11_RS09960 a26f6f355e0808cb85a77c4ef7255a21 346 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 335 2.0E-90 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMD11_RS09960 a26f6f355e0808cb85a77c4ef7255a21 346 Gene3D G3DSA:3.40.718.10 5 339 1.6E-115 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMD11_RS09960 a26f6f355e0808cb85a77c4ef7255a21 346 SUPERFAMILY SSF53659 4 342 1.92E-110 T 06-07-2017 SMD11_RS33480 8167594df4928cf11523c01fa1e23ed4 454 Gene3D G3DSA:3.40.50.980 7 144 4.8E-15 T 06-07-2017 SMD11_RS33480 8167594df4928cf11523c01fa1e23ed4 454 Pfam PF13193 AMP-binding enzyme C-terminal domain 371 443 4.7E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS33480 8167594df4928cf11523c01fa1e23ed4 454 SUPERFAMILY SSF56801 3 451 1.03E-82 T 06-07-2017 SMD11_RS33480 8167594df4928cf11523c01fa1e23ed4 454 Gene3D G3DSA:3.40.50.980 145 289 1.8E-24 T 06-07-2017 SMD11_RS33480 8167594df4928cf11523c01fa1e23ed4 454 Pfam PF00501 AMP-binding enzyme 8 362 7.9E-48 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS33480 8167594df4928cf11523c01fa1e23ed4 454 ProSitePatterns PS00455 Putative AMP-binding domain signature. 134 145 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS33480 8167594df4928cf11523c01fa1e23ed4 454 Gene3D G3DSA:3.30.300.30 357 451 2.4E-13 T 06-07-2017 SMD11_RS33480 8167594df4928cf11523c01fa1e23ed4 454 Gene3D G3DSA:2.30.38.10 307 356 2.2E-12 T 06-07-2017 SMD11_RS14005 a449d6f54936da8278c9607d7c205ba2 1350 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 413 676 7.2E-11 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS14005 a449d6f54936da8278c9607d7c205ba2 1350 SUPERFAMILY SSF52266 389 686 7.0E-36 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS14005 a449d6f54936da8278c9607d7c205ba2 1350 SUPERFAMILY SSF52266 341 355 7.0E-36 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS14005 a449d6f54936da8278c9607d7c205ba2 1350 SUPERFAMILY SSF51126 764 877 3.66E-12 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor SMD11_RS14005 a449d6f54936da8278c9607d7c205ba2 1350 SUPERFAMILY SSF51126 1084 1214 3.66E-12 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor SMD11_RS14005 a449d6f54936da8278c9607d7c205ba2 1350 Gene3D G3DSA:3.40.50.1110 390 686 6.1E-43 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS14005 a449d6f54936da8278c9607d7c205ba2 1350 Gene3D G3DSA:3.40.50.1110 340 356 6.1E-43 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS14005 a449d6f54936da8278c9607d7c205ba2 1350 Gene3D G3DSA:3.60.10.10 179 303 5.1E-13 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS14005 a449d6f54936da8278c9607d7c205ba2 1350 SUPERFAMILY SSF56219 32 67 7.05E-11 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS14005 a449d6f54936da8278c9607d7c205ba2 1350 SUPERFAMILY SSF56219 118 301 7.05E-11 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS14005 a449d6f54936da8278c9607d7c205ba2 1350 Gene3D G3DSA:2.160.20.10 764 881 2.6E-15 T 06-07-2017 IPR012334 Pectin lyase fold SMD11_RS14005 a449d6f54936da8278c9607d7c205ba2 1350 Gene3D G3DSA:2.160.20.10 1094 1268 2.6E-15 T 06-07-2017 IPR012334 Pectin lyase fold SMD11_RS10845 1ee3de23715e913f18729cbc339127e6 281 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 4 278 41.968 T 06-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 SMD11_RS10845 1ee3de23715e913f18729cbc339127e6 281 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 181 187 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMD11_RS10845 1ee3de23715e913f18729cbc339127e6 281 SUPERFAMILY SSF53335 17 249 3.17E-48 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS10845 1ee3de23715e913f18729cbc339127e6 281 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 26 274 1.1E-71 T 06-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 SMD11_RS10845 1ee3de23715e913f18729cbc339127e6 281 Pfam PF05175 Methyltransferase small domain 114 187 2.1E-12 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 SMD11_RS10845 1ee3de23715e913f18729cbc339127e6 281 Gene3D G3DSA:1.10.8.10 8 83 3.7E-17 T 06-07-2017 SMD11_RS10845 1ee3de23715e913f18729cbc339127e6 281 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 22 278 7.2E-51 T 06-07-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 SMD11_RS10845 1ee3de23715e913f18729cbc339127e6 281 Gene3D G3DSA:3.40.50.150 85 278 9.7E-57 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS01455 d542bfa282adc6114cd28593533c94a9 1066 Pfam PF00501 AMP-binding enzyme 42 446 3.6E-85 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS01455 d542bfa282adc6114cd28593533c94a9 1066 Gene3D G3DSA:3.40.50.980 212 357 2.9E-34 T 06-07-2017 SMD11_RS01455 d542bfa282adc6114cd28593533c94a9 1066 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS01455 d542bfa282adc6114cd28593533c94a9 1066 Gene3D G3DSA:1.10.1200.10 553 634 2.4E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01455 d542bfa282adc6114cd28593533c94a9 1066 Gene3D G3DSA:3.40.50.720 674 960 2.4E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS01455 d542bfa282adc6114cd28593533c94a9 1066 SUPERFAMILY SSF56801 36 532 1.09E-125 T 06-07-2017 SMD11_RS01455 d542bfa282adc6114cd28593533c94a9 1066 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 675 1043 6.9E-97 T 06-07-2017 IPR010080 Thioester reductase-like domain SMD11_RS01455 d542bfa282adc6114cd28593533c94a9 1066 Gene3D G3DSA:2.30.38.10 358 435 3.1E-19 T 06-07-2017 SMD11_RS01455 d542bfa282adc6114cd28593533c94a9 1066 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 63 470 6.6E-119 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS01455 d542bfa282adc6114cd28593533c94a9 1066 Gene3D G3DSA:3.30.300.30 440 533 7.1E-21 T 06-07-2017 SMD11_RS01455 d542bfa282adc6114cd28593533c94a9 1066 Pfam PF07993 Male sterility protein 677 913 2.5E-60 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 SMD11_RS01455 d542bfa282adc6114cd28593533c94a9 1066 Pfam PF00550 Phosphopantetheine attachment site 563 598 1.3E-4 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01455 d542bfa282adc6114cd28593533c94a9 1066 SUPERFAMILY SSF47336 558 627 5.44E-6 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01455 d542bfa282adc6114cd28593533c94a9 1066 Gene3D G3DSA:3.40.50.980 35 211 1.1E-41 T 06-07-2017 SMD11_RS01455 d542bfa282adc6114cd28593533c94a9 1066 SUPERFAMILY SSF51735 675 969 6.33E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS25480 c6e359ab1865e7ded439950a11fa70ab 251 Gene3D G3DSA:3.40.50.720 1 246 6.1E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS25480 c6e359ab1865e7ded439950a11fa70ab 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS25480 c6e359ab1865e7ded439950a11fa70ab 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS25480 c6e359ab1865e7ded439950a11fa70ab 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS25480 c6e359ab1865e7ded439950a11fa70ab 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS25480 c6e359ab1865e7ded439950a11fa70ab 251 SUPERFAMILY SSF51735 1 247 1.97E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS25480 c6e359ab1865e7ded439950a11fa70ab 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 7.4E-46 T 06-07-2017 SMD11_RS19855 3103e68de19da0a9750fb49e9f90ed87 423 SUPERFAMILY SSF63882 1 191 4.58E-48 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS19855 3103e68de19da0a9750fb49e9f90ed87 423 Gene3D G3DSA:2.170.190.11 41 146 4.6E-32 T 06-07-2017 SMD11_RS19855 3103e68de19da0a9750fb49e9f90ed87 423 Pfam PF03454 MoeA C-terminal region (domain IV) 360 419 1.7E-14 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS19855 3103e68de19da0a9750fb49e9f90ed87 423 Pfam PF03453 MoeA N-terminal region (domain I and II) 1 182 6.5E-34 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS19855 3103e68de19da0a9750fb49e9f90ed87 423 Gene3D G3DSA:3.90.105.10 147 177 1.2E-19 T 06-07-2017 SMD11_RS19855 3103e68de19da0a9750fb49e9f90ed87 423 SUPERFAMILY SSF63867 347 420 1.26E-14 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS19855 3103e68de19da0a9750fb49e9f90ed87 423 Gene3D G3DSA:3.40.980.10 178 350 2.5E-59 T 06-07-2017 IPR001453 MoaB/Mog domain SMD11_RS19855 3103e68de19da0a9750fb49e9f90ed87 423 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 192 334 1.6E-30 T 06-07-2017 IPR001453 MoaB/Mog domain SMD11_RS19855 3103e68de19da0a9750fb49e9f90ed87 423 SMART SM00852 195 338 8.9E-41 T 06-07-2017 IPR001453 MoaB/Mog domain SMD11_RS19855 3103e68de19da0a9750fb49e9f90ed87 423 Pfam PF00994 Probable molybdopterin binding domain 196 337 6.4E-28 T 06-07-2017 IPR001453 MoaB/Mog domain SMD11_RS19855 3103e68de19da0a9750fb49e9f90ed87 423 Gene3D G3DSA:2.40.340.10 351 420 8.2E-19 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS19855 3103e68de19da0a9750fb49e9f90ed87 423 SUPERFAMILY SSF53218 191 342 4.58E-39 T 06-07-2017 IPR001453 MoaB/Mog domain SMD11_RS16760 f077ef7c3cfa576402267378dffb80c1 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 147 3.1E-27 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal SMD11_RS16760 f077ef7c3cfa576402267378dffb80c1 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.234 T 06-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS16760 f077ef7c3cfa576402267378dffb80c1 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16760 f077ef7c3cfa576402267378dffb80c1 148 SUPERFAMILY SSF55658 1 56 1.26E-16 T 06-07-2017 IPR009027 Ribosomal protein L9/RNase H1, N-terminal SMD11_RS16760 f077ef7c3cfa576402267378dffb80c1 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.5E-38 T 06-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS16760 f077ef7c3cfa576402267378dffb80c1 148 SUPERFAMILY SSF55653 58 147 6.02E-24 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal SMD11_RS16760 f077ef7c3cfa576402267378dffb80c1 148 Gene3D G3DSA:3.10.430.100 62 147 1.9E-28 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal SMD11_RS16760 f077ef7c3cfa576402267378dffb80c1 148 Gene3D G3DSA:3.40.5.10 1 51 2.8E-21 T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16760 f077ef7c3cfa576402267378dffb80c1 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 42 8.7E-21 T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS24185 3e088a0c6df84db489187c71c0bd0fd5 467 Pfam PF01206 Sulfurtransferase TusA 397 465 5.6E-13 T 06-07-2017 IPR001455 TusA-like domain SMD11_RS24185 3e088a0c6df84db489187c71c0bd0fd5 467 SUPERFAMILY SSF53383 3 366 1.79E-76 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS24185 3e088a0c6df84db489187c71c0bd0fd5 467 Gene3D G3DSA:3.90.1150.10 243 363 1.1E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS24185 3e088a0c6df84db489187c71c0bd0fd5 467 Pfam PF00266 Aminotransferase class-V 3 358 6.2E-43 T 06-07-2017 IPR000192 Aminotransferase class V domain SMD11_RS24185 3e088a0c6df84db489187c71c0bd0fd5 467 Gene3D G3DSA:3.30.110.40 396 465 1.6E-17 T 06-07-2017 IPR001455 TusA-like domain SMD11_RS24185 3e088a0c6df84db489187c71c0bd0fd5 467 Gene3D G3DSA:3.40.640.10 14 242 2.0E-55 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS24185 3e088a0c6df84db489187c71c0bd0fd5 467 SUPERFAMILY SSF64307 397 465 7.85E-16 T 06-07-2017 IPR001455 TusA-like domain SMD11_RS24185 3e088a0c6df84db489187c71c0bd0fd5 467 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 398 422 - T 06-07-2017 IPR001455 TusA-like domain SMD11_RS02980 af1e65befec05d794ffd1379ad8cca5d 232 Gene3D G3DSA:3.40.30.10 13 189 1.7E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS02980 af1e65befec05d794ffd1379ad8cca5d 232 SUPERFAMILY SSF52833 13 192 4.47E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS02980 af1e65befec05d794ffd1379ad8cca5d 232 Pfam PF01323 DSBA-like thioredoxin domain 16 193 4.8E-10 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMD11_RS05475 a3af1f185df1a7f76338c190a5ec3489 728 Gene3D G3DSA:1.10.1040.10 509 607 9.3E-11 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS05475 a3af1f185df1a7f76338c190a5ec3489 728 Gene3D G3DSA:3.90.226.10 244 303 4.7E-56 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS05475 a3af1f185df1a7f76338c190a5ec3489 728 Gene3D G3DSA:3.90.226.10 4 210 4.7E-56 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS05475 a3af1f185df1a7f76338c190a5ec3489 728 SUPERFAMILY SSF48179 638 725 4.34E-14 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS05475 a3af1f185df1a7f76338c190a5ec3489 728 SUPERFAMILY SSF52096 7 315 2.72E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS05475 a3af1f185df1a7f76338c190a5ec3489 728 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 326 504 4.4E-64 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS05475 a3af1f185df1a7f76338c190a5ec3489 728 Gene3D G3DSA:1.10.1040.10 650 728 9.1E-8 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS05475 a3af1f185df1a7f76338c190a5ec3489 728 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 507 607 2.2E-16 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS05475 a3af1f185df1a7f76338c190a5ec3489 728 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 328 356 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS05475 a3af1f185df1a7f76338c190a5ec3489 728 SUPERFAMILY SSF48179 506 649 2.81E-16 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS05475 a3af1f185df1a7f76338c190a5ec3489 728 Gene3D G3DSA:3.40.50.720 321 508 5.8E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05475 a3af1f185df1a7f76338c190a5ec3489 728 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 211 1.9E-32 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS05475 a3af1f185df1a7f76338c190a5ec3489 728 SUPERFAMILY SSF51735 324 505 5.59E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20095 c2c45278e739f59672e40c8946d40aa3 849 Pfam PF12704 MacB-like periplasmic core domain 19 234 3.3E-12 T 06-07-2017 IPR025857 MacB-like periplasmic core domain SMD11_RS20095 c2c45278e739f59672e40c8946d40aa3 849 Pfam PF12704 MacB-like periplasmic core domain 498 695 7.8E-7 T 06-07-2017 IPR025857 MacB-like periplasmic core domain SMD11_RS20095 c2c45278e739f59672e40c8946d40aa3 849 Pfam PF02687 FtsX-like permease family 736 843 1.3E-13 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 SMD11_RS20095 c2c45278e739f59672e40c8946d40aa3 849 Pfam PF02687 FtsX-like permease family 275 391 1.1E-12 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 SMD11_RS01610 573be8b7ac7d5b0e97638ef2060e07bb 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 185 0.0051 T 06-07-2017 SMD11_RS01610 573be8b7ac7d5b0e97638ef2060e07bb 245 SUPERFAMILY SSF51735 5 243 9.59E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS01610 573be8b7ac7d5b0e97638ef2060e07bb 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 240 4.7E-42 T 06-07-2017 SMD11_RS01610 573be8b7ac7d5b0e97638ef2060e07bb 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 1.3E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01610 573be8b7ac7d5b0e97638ef2060e07bb 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.3E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01610 573be8b7ac7d5b0e97638ef2060e07bb 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.3E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01610 573be8b7ac7d5b0e97638ef2060e07bb 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.3E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01610 573be8b7ac7d5b0e97638ef2060e07bb 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01610 573be8b7ac7d5b0e97638ef2060e07bb 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 1.3E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01610 573be8b7ac7d5b0e97638ef2060e07bb 245 Gene3D G3DSA:3.40.50.720 4 243 1.0E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS01610 573be8b7ac7d5b0e97638ef2060e07bb 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01610 573be8b7ac7d5b0e97638ef2060e07bb 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01610 573be8b7ac7d5b0e97638ef2060e07bb 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS22205 e9824ac8952d2e60654ab7c0ad4be73a 865 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 859 0.0 T 06-07-2017 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 SMD11_RS22205 e9824ac8952d2e60654ab7c0ad4be73a 865 Gene3D G3DSA:1.10.390.10 322 467 2.1E-41 T 06-07-2017 SMD11_RS22205 e9824ac8952d2e60654ab7c0ad4be73a 865 SUPERFAMILY SSF63737 5 204 2.09E-40 T 06-07-2017 SMD11_RS22205 e9824ac8952d2e60654ab7c0ad4be73a 865 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 187 202 8.7E-18 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS22205 e9824ac8952d2e60654ab7c0ad4be73a 865 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 138 153 8.7E-18 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS22205 e9824ac8952d2e60654ab7c0ad4be73a 865 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 328 340 8.7E-18 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS22205 e9824ac8952d2e60654ab7c0ad4be73a 865 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 309 324 8.7E-18 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS22205 e9824ac8952d2e60654ab7c0ad4be73a 865 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 275 285 8.7E-18 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS22205 e9824ac8952d2e60654ab7c0ad4be73a 865 Pfam PF11838 ERAP1-like C-terminal domain 541 852 1.5E-64 T 06-07-2017 IPR024571 ERAP1-like C-terminal domain SMD11_RS22205 e9824ac8952d2e60654ab7c0ad4be73a 865 SUPERFAMILY SSF55486 222 467 1.9E-74 T 06-07-2017 SMD11_RS22205 e9824ac8952d2e60654ab7c0ad4be73a 865 Pfam PF01433 Peptidase family M1 100 401 1.4E-64 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS28280 579a40b8c1a933691179bd2fa797c423 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 244 8.6E-57 T 06-07-2017 SMD11_RS28280 579a40b8c1a933691179bd2fa797c423 250 SUPERFAMILY SSF51735 7 245 6.71E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS28280 579a40b8c1a933691179bd2fa797c423 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.6E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28280 579a40b8c1a933691179bd2fa797c423 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.6E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28280 579a40b8c1a933691179bd2fa797c423 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.6E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28280 579a40b8c1a933691179bd2fa797c423 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 7.8E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28280 579a40b8c1a933691179bd2fa797c423 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.8E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28280 579a40b8c1a933691179bd2fa797c423 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.8E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28280 579a40b8c1a933691179bd2fa797c423 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 7.8E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28280 579a40b8c1a933691179bd2fa797c423 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 7.8E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28280 579a40b8c1a933691179bd2fa797c423 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 7.8E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28280 579a40b8c1a933691179bd2fa797c423 250 Gene3D G3DSA:3.40.50.720 6 246 8.7E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS28280 579a40b8c1a933691179bd2fa797c423 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS10155 b593b75e0d5e5692ba4c7d735bc034e0 229 SUPERFAMILY SSF51735 3 213 9.01E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10155 b593b75e0d5e5692ba4c7d735bc034e0 229 Gene3D G3DSA:3.40.50.720 4 215 1.4E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10155 b593b75e0d5e5692ba4c7d735bc034e0 229 Pfam PF00106 short chain dehydrogenase 5 189 7.5E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS10155 b593b75e0d5e5692ba4c7d735bc034e0 229 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS10155 b593b75e0d5e5692ba4c7d735bc034e0 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.5E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS10155 b593b75e0d5e5692ba4c7d735bc034e0 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.5E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS10155 b593b75e0d5e5692ba4c7d735bc034e0 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.5E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS10155 b593b75e0d5e5692ba4c7d735bc034e0 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.5E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS10155 b593b75e0d5e5692ba4c7d735bc034e0 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.5E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17120 3fd5a1945d45004974c7ab4ae3c30f02 249 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 23 249 7.0E-73 T 06-07-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 SMD11_RS17120 3fd5a1945d45004974c7ab4ae3c30f02 249 Gene3D G3DSA:1.20.1260.10 19 249 2.7E-78 T 06-07-2017 IPR012347 Ferritin-related SMD11_RS17120 3fd5a1945d45004974c7ab4ae3c30f02 249 SUPERFAMILY SSF47240 20 243 1.24E-61 T 06-07-2017 IPR009078 Ferritin-like superfamily SMD11_RS17120 3fd5a1945d45004974c7ab4ae3c30f02 249 PIRSF PIRSF037834 9 249 1.9E-87 T 06-07-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 SMD11_RS17120 3fd5a1945d45004974c7ab4ae3c30f02 249 Pfam PF05138 Phenylacetic acid catabolic protein 19 249 5.9E-72 T 06-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 SMD11_RS10485 e639587ecbbacd1750341b6a3d349c57 184 ProSitePatterns PS00018 EF-hand calcium-binding domain. 107 119 - T 06-07-2017 IPR018247 EF-Hand 1, calcium-binding site SMD11_RS10485 e639587ecbbacd1750341b6a3d349c57 184 ProSitePatterns PS00018 EF-hand calcium-binding domain. 23 35 - T 06-07-2017 IPR018247 EF-Hand 1, calcium-binding site SMD11_RS10485 e639587ecbbacd1750341b6a3d349c57 184 ProSitePatterns PS00018 EF-hand calcium-binding domain. 141 153 - T 06-07-2017 IPR018247 EF-Hand 1, calcium-binding site SMD11_RS10485 e639587ecbbacd1750341b6a3d349c57 184 Gene3D G3DSA:1.10.238.10 73 114 9.8E-9 T 06-07-2017 IPR011992 EF-hand domain pair SMD11_RS10485 e639587ecbbacd1750341b6a3d349c57 184 Pfam PF13202 EF hand 18 35 5.0E-4 T 06-07-2017 IPR002048 EF-hand domain GO:0005509 SMD11_RS10485 e639587ecbbacd1750341b6a3d349c57 184 Pfam PF13202 EF hand 67 81 0.025 T 06-07-2017 IPR002048 EF-hand domain GO:0005509 SMD11_RS10485 e639587ecbbacd1750341b6a3d349c57 184 Gene3D G3DSA:1.10.238.10 115 166 9.2E-10 T 06-07-2017 IPR011992 EF-hand domain pair SMD11_RS10485 e639587ecbbacd1750341b6a3d349c57 184 Gene3D G3DSA:1.10.238.10 18 32 2.4E-6 T 06-07-2017 IPR011992 EF-hand domain pair SMD11_RS10485 e639587ecbbacd1750341b6a3d349c57 184 SUPERFAMILY SSF47473 16 161 6.16E-23 T 06-07-2017 IPR011992 EF-hand domain pair SMD11_RS10485 e639587ecbbacd1750341b6a3d349c57 184 SMART SM00054 132 160 3.0 T 06-07-2017 IPR002048 EF-hand domain GO:0005509 SMD11_RS10485 e639587ecbbacd1750341b6a3d349c57 184 SMART SM00054 61 89 6.0 T 06-07-2017 IPR002048 EF-hand domain GO:0005509 SMD11_RS10485 e639587ecbbacd1750341b6a3d349c57 184 SMART SM00054 14 42 6.2 T 06-07-2017 IPR002048 EF-hand domain GO:0005509 SMD11_RS10485 e639587ecbbacd1750341b6a3d349c57 184 SMART SM00054 98 126 0.76 T 06-07-2017 IPR002048 EF-hand domain GO:0005509 SMD11_RS10485 e639587ecbbacd1750341b6a3d349c57 184 Gene3D G3DSA:1.10.238.10 33 72 5.0E-5 T 06-07-2017 IPR011992 EF-hand domain pair SMD11_RS10485 e639587ecbbacd1750341b6a3d349c57 184 Pfam PF13499 EF-hand domain pair 98 155 2.9E-8 T 06-07-2017 IPR002048 EF-hand domain GO:0005509 SMD11_RS29880 e2258c316cf81c6ef83d09b076e698b1 160 Gene3D G3DSA:3.10.450.50 17 158 8.1E-29 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS29880 e2258c316cf81c6ef83d09b076e698b1 160 SUPERFAMILY SSF54427 8 158 2.93E-28 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS29880 e2258c316cf81c6ef83d09b076e698b1 160 Pfam PF13577 SnoaL-like domain 17 145 1.2E-22 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain SMD11_RS09950 f0624e3389ec9477d08d33e830202b7e 470 ProSitePatterns PS00216 Sugar transport proteins signature 1. 299 316 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS09950 f0624e3389ec9477d08d33e830202b7e 470 ProSitePatterns PS00217 Sugar transport proteins signature 2. 130 155 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS09950 f0624e3389ec9477d08d33e830202b7e 470 SUPERFAMILY SSF103473 16 436 3.01E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS09950 f0624e3389ec9477d08d33e830202b7e 470 Gene3D G3DSA:1.20.1250.20 231 428 2.3E-23 T 06-07-2017 SMD11_RS09950 f0624e3389ec9477d08d33e830202b7e 470 Gene3D G3DSA:1.20.1250.20 14 226 3.1E-24 T 06-07-2017 SMD11_RS09950 f0624e3389ec9477d08d33e830202b7e 470 Pfam PF07690 Major Facilitator Superfamily 33 372 1.7E-25 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS13995 93c6548d6a45de6a1c5af0cca0c871c1 142 SUPERFAMILY SSF75620 11 102 1.57E-12 T 06-07-2017 SMD11_RS13995 93c6548d6a45de6a1c5af0cca0c871c1 142 Pfam PF00472 RF-1 domain 10 134 2.9E-22 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SMD11_RS13995 93c6548d6a45de6a1c5af0cca0c871c1 142 Gene3D G3DSA:3.30.160.200 10 107 2.1E-28 T 06-07-2017 SMD11_RS14445 b0850aadeb7abf50cfc49749689dc337 145 SUPERFAMILY SSF46785 6 135 4.89E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14445 b0850aadeb7abf50cfc49749689dc337 145 Gene3D G3DSA:1.10.10.10 5 82 1.4E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14445 b0850aadeb7abf50cfc49749689dc337 145 Pfam PF01475 Ferric uptake regulator family 12 104 2.7E-22 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 SMD11_RS31825 cc431743674df8d36584b90bc388c4f6 360 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 33 56 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS31825 cc431743674df8d36584b90bc388c4f6 360 SMART SM00220 27 287 6.8E-59 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS31825 cc431743674df8d36584b90bc388c4f6 360 Pfam PF00069 Protein kinase domain 27 242 1.5E-46 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS31825 cc431743674df8d36584b90bc388c4f6 360 SUPERFAMILY SSF56112 26 292 3.1E-72 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS31825 cc431743674df8d36584b90bc388c4f6 360 Gene3D G3DSA:3.30.200.20 23 92 2.8E-22 T 06-07-2017 SMD11_RS31825 cc431743674df8d36584b90bc388c4f6 360 Gene3D G3DSA:1.10.510.10 93 281 2.8E-47 T 06-07-2017 SMD11_RS31825 cc431743674df8d36584b90bc388c4f6 360 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 146 158 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS03735 cfea82f690746723d6ae0caa8496b216 432 Gene3D G3DSA:3.40.190.10 48 176 3.9E-23 T 06-07-2017 SMD11_RS03735 cfea82f690746723d6ae0caa8496b216 432 Pfam PF13416 Bacterial extracellular solute-binding protein 62 365 3.3E-38 T 06-07-2017 SMD11_RS03735 cfea82f690746723d6ae0caa8496b216 432 SUPERFAMILY SSF53850 22 430 1.43E-70 T 06-07-2017 SMD11_RS03735 cfea82f690746723d6ae0caa8496b216 432 Gene3D G3DSA:3.40.190.10 177 352 2.8E-27 T 06-07-2017 SMD11_RS15370 75ad78d19c6a0f9c4faa400a6dd4ad30 655 Gene3D G3DSA:2.30.38.10 444 519 4.5E-6 T 06-07-2017 SMD11_RS15370 75ad78d19c6a0f9c4faa400a6dd4ad30 655 Pfam PF00501 AMP-binding enzyme 92 526 1.5E-88 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS15370 75ad78d19c6a0f9c4faa400a6dd4ad30 655 Pfam PF13193 AMP-binding enzyme C-terminal domain 535 614 5.2E-27 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS15370 75ad78d19c6a0f9c4faa400a6dd4ad30 655 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 31 83 2.6E-20 T 06-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 SMD11_RS15370 75ad78d19c6a0f9c4faa400a6dd4ad30 655 Gene3D G3DSA:3.40.50.980 81 269 1.1E-40 T 06-07-2017 SMD11_RS15370 75ad78d19c6a0f9c4faa400a6dd4ad30 655 Gene3D G3DSA:3.40.50.980 270 428 9.4E-27 T 06-07-2017 SMD11_RS15370 75ad78d19c6a0f9c4faa400a6dd4ad30 655 Gene3D G3DSA:3.30.300.30 523 647 2.1E-29 T 06-07-2017 SMD11_RS15370 75ad78d19c6a0f9c4faa400a6dd4ad30 655 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 11 648 50.726 T 06-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 SMD11_RS15370 75ad78d19c6a0f9c4faa400a6dd4ad30 655 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 27 646 1.1E-292 T 06-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 SMD11_RS15370 75ad78d19c6a0f9c4faa400a6dd4ad30 655 SUPERFAMILY SSF56801 32 642 2.09E-172 T 06-07-2017 SMD11_RS15370 75ad78d19c6a0f9c4faa400a6dd4ad30 655 ProSitePatterns PS00455 Putative AMP-binding domain signature. 264 275 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS21920 87d2ad4029ff1c3935842177745b3bb8 252 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMD11_RS21920 87d2ad4029ff1c3935842177745b3bb8 252 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 119 1.5E-24 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS21920 87d2ad4029ff1c3935842177745b3bb8 252 SUPERFAMILY SSF54292 3 115 1.05E-20 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS21920 87d2ad4029ff1c3935842177745b3bb8 252 Gene3D G3DSA:3.10.20.30 2 110 5.4E-29 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS21920 87d2ad4029ff1c3935842177745b3bb8 252 Gene3D G3DSA:1.10.1060.10 111 241 4.1E-19 T 06-07-2017 SMD11_RS21920 87d2ad4029ff1c3935842177745b3bb8 252 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 158 169 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD11_RS21920 87d2ad4029ff1c3935842177745b3bb8 252 SUPERFAMILY SSF46548 118 241 3.49E-23 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 SMD11_RS21920 87d2ad4029ff1c3935842177745b3bb8 252 Pfam PF13183 4Fe-4S dicluster domain 157 227 3.8E-10 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD11_RS04395 690f8ffd844335e3e18178fba4f90300 803 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 411 587 1.3E-85 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 SMD11_RS04395 690f8ffd844335e3e18178fba4f90300 803 Gene3D G3DSA:3.40.50.970 66 267 2.9E-19 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS04395 690f8ffd844335e3e18178fba4f90300 803 PIRSF PIRSF017245 3 802 0.0 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 SMD11_RS04395 690f8ffd844335e3e18178fba4f90300 803 Hamap MF_01403 Probable phosphoketolase. 17 802 40.737 T 06-07-2017 IPR023962 Probable phosphoketolase SMD11_RS04395 690f8ffd844335e3e18178fba4f90300 803 SUPERFAMILY SSF52518 19 381 7.71E-74 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS04395 690f8ffd844335e3e18178fba4f90300 803 ProSitePatterns PS60003 Phosphoketolase signature 2. 169 187 - T 06-07-2017 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 SMD11_RS04395 690f8ffd844335e3e18178fba4f90300 803 Pfam PF09364 XFP N-terminal domain 20 396 5.2E-180 T 06-07-2017 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal SMD11_RS04395 690f8ffd844335e3e18178fba4f90300 803 ProSitePatterns PS60002 Phosphoketolase signature 1. 156 162 - T 06-07-2017 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 SMD11_RS04395 690f8ffd844335e3e18178fba4f90300 803 SUPERFAMILY SSF52518 389 600 1.0E-23 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS04395 690f8ffd844335e3e18178fba4f90300 803 Pfam PF09363 XFP C-terminal domain 598 800 3.9E-83 T 06-07-2017 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 SMD11_RS32695 305760ca76ba3c8e352a644b8747e656 459 Pfam PF00120 Glutamine synthetase, catalytic domain 129 454 5.1E-83 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS32695 305760ca76ba3c8e352a644b8747e656 459 SUPERFAMILY SSF54368 17 127 3.92E-15 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS32695 305760ca76ba3c8e352a644b8747e656 459 Gene3D G3DSA:3.30.590.10 132 444 4.5E-81 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SMD11_RS32695 305760ca76ba3c8e352a644b8747e656 459 SMART SM01230 128 376 1.4E-78 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS32695 305760ca76ba3c8e352a644b8747e656 459 SUPERFAMILY SSF55931 128 456 1.47E-85 T 06-07-2017 SMD11_RS32695 305760ca76ba3c8e352a644b8747e656 459 Gene3D G3DSA:3.10.20.70 19 131 4.7E-8 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS03845 91ab93a32d4eee5946bc72358db31f6c 286 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 75 5.0E-9 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS03845 91ab93a32d4eee5946bc72358db31f6c 286 Pfam PF00378 Enoyl-CoA hydratase/isomerase 114 256 3.7E-24 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS03845 91ab93a32d4eee5946bc72358db31f6c 286 Gene3D G3DSA:3.90.226.10 5 253 3.7E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS03845 91ab93a32d4eee5946bc72358db31f6c 286 SUPERFAMILY SSF52096 9 263 1.57E-63 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS01680 88a5cb6521687ffc6335ce1981e13fe4 144 SUPERFAMILY SSF54593 6 35 2.74E-13 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS01680 88a5cb6521687ffc6335ce1981e13fe4 144 SUPERFAMILY SSF54593 89 143 2.74E-13 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS01680 88a5cb6521687ffc6335ce1981e13fe4 144 Gene3D G3DSA:3.10.180.10 7 143 4.0E-13 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 SUPERFAMILY SSF52935 321 471 6.93E-38 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 SUPERFAMILY SSF50800 70 165 2.09E-26 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 Pfam PF02887 Pyruvate kinase, alpha/beta domain 357 469 2.6E-28 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 PRINTS PR01050 Pyruvate kinase family signature 59 75 3.3E-65 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 PRINTS PR01050 Pyruvate kinase family signature 267 291 3.3E-65 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 PRINTS PR01050 Pyruvate kinase family signature 185 199 3.3E-65 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 PRINTS PR01050 Pyruvate kinase family signature 242 266 3.3E-65 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 PRINTS PR01050 Pyruvate kinase family signature 292 310 3.3E-65 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 PRINTS PR01050 Pyruvate kinase family signature 215 241 3.3E-65 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 PRINTS PR01050 Pyruvate kinase family signature 311 327 3.3E-65 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 Gene3D G3DSA:3.20.20.60 168 324 5.0E-103 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 Gene3D G3DSA:3.20.20.60 2 72 5.0E-103 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 Gene3D G3DSA:3.40.1380.20 325 471 4.4E-43 T 06-07-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 471 1.2E-165 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 Pfam PF00224 Pyruvate kinase, barrel domain 1 337 8.0E-125 T 06-07-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 SUPERFAMILY SSF51621 166 338 1.26E-98 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 SUPERFAMILY SSF51621 1 75 1.26E-98 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 06-07-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS24895 ea369e4a943deba5af15dddef65a1016 474 Gene3D G3DSA:2.40.33.10 73 167 1.3E-29 T 06-07-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS20475 a43d7da4ea1363206690d573038b1de6 497 SUPERFAMILY SSF56801 64 495 1.02E-110 T 06-07-2017 SMD11_RS20475 a43d7da4ea1363206690d573038b1de6 497 Gene3D G3DSA:3.30.300.30 404 495 9.0E-29 T 06-07-2017 SMD11_RS20475 a43d7da4ea1363206690d573038b1de6 497 Pfam PF00501 AMP-binding enzyme 81 401 2.7E-62 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS20475 a43d7da4ea1363206690d573038b1de6 497 ProSitePatterns PS00455 Putative AMP-binding domain signature. 172 183 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS20475 a43d7da4ea1363206690d573038b1de6 497 Pfam PF13193 AMP-binding enzyme C-terminal domain 416 488 3.2E-20 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS20475 a43d7da4ea1363206690d573038b1de6 497 Gene3D G3DSA:2.30.38.10 331 397 1.1E-19 T 06-07-2017 SMD11_RS20475 a43d7da4ea1363206690d573038b1de6 497 Gene3D G3DSA:3.40.50.980 92 179 9.4E-18 T 06-07-2017 SMD11_RS20475 a43d7da4ea1363206690d573038b1de6 497 Gene3D G3DSA:3.40.50.980 180 330 1.2E-29 T 06-07-2017 SMD11_RS18035 80b16e2704344d9a0e1762747c2b75b9 475 Pfam PF01551 Peptidase family M23 370 464 1.2E-24 T 06-07-2017 IPR016047 Peptidase M23 SMD11_RS18035 80b16e2704344d9a0e1762747c2b75b9 475 Gene3D G3DSA:2.70.70.10 336 469 4.1E-39 T 06-07-2017 SMD11_RS18035 80b16e2704344d9a0e1762747c2b75b9 475 SUPERFAMILY SSF51261 334 468 7.32E-41 T 06-07-2017 IPR011055 Duplicated hybrid motif SMD11_RS02415 81574736d6d96e252e45a6bba0a27831 241 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 79 5.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS02415 81574736d6d96e252e45a6bba0a27831 241 Gene3D G3DSA:1.10.357.10 22 239 5.2E-58 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS02415 81574736d6d96e252e45a6bba0a27831 241 SUPERFAMILY SSF48498 97 239 7.38E-28 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS02415 81574736d6d96e252e45a6bba0a27831 241 SUPERFAMILY SSF46689 23 88 1.65E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS02415 81574736d6d96e252e45a6bba0a27831 241 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 94 235 1.4E-21 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD11_RS25095 da00e5eadca17f4031ab9208b37ebe4b 672 SUPERFAMILY SSF46600 194 246 1.7E-12 T 06-07-2017 IPR001943 UVR domain GO:0005515 SMD11_RS25095 da00e5eadca17f4031ab9208b37ebe4b 672 Gene3D G3DSA:4.10.860.10 187 246 8.4E-17 T 06-07-2017 IPR001943 UVR domain GO:0005515 SMD11_RS25095 da00e5eadca17f4031ab9208b37ebe4b 672 Pfam PF14520 Helix-hairpin-helix domain 599 649 4.0E-9 T 06-07-2017 SMD11_RS25095 da00e5eadca17f4031ab9208b37ebe4b 672 Pfam PF01541 GIY-YIG catalytic domain 19 92 1.3E-11 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily SMD11_RS25095 da00e5eadca17f4031ab9208b37ebe4b 672 Pfam PF02151 UvrB/uvrC motif 210 242 5.3E-9 T 06-07-2017 IPR001943 UVR domain GO:0005515 SMD11_RS25095 da00e5eadca17f4031ab9208b37ebe4b 672 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 393 583 4.0E-52 T 06-07-2017 IPR001162 UvrC family homology region SMD11_RS25095 da00e5eadca17f4031ab9208b37ebe4b 672 Gene3D G3DSA:1.10.150.20 599 649 7.2E-20 T 06-07-2017 SMD11_RS25095 da00e5eadca17f4031ab9208b37ebe4b 672 SMART SM00278 629 648 1.2 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SMD11_RS25095 da00e5eadca17f4031ab9208b37ebe4b 672 SMART SM00278 597 616 100.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SMD11_RS25095 da00e5eadca17f4031ab9208b37ebe4b 672 Gene3D G3DSA:3.40.1440.10 18 95 3.1E-10 T 06-07-2017 IPR027299 GIY-YIG domain SMD11_RS25095 da00e5eadca17f4031ab9208b37ebe4b 672 SMART SM00465 17 99 6.7E-21 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily SMD11_RS25095 da00e5eadca17f4031ab9208b37ebe4b 672 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 11 466 1.3E-129 T 06-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 SMD11_RS25095 da00e5eadca17f4031ab9208b37ebe4b 672 SUPERFAMILY SSF82771 17 101 1.57E-23 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily SMD11_RS25095 da00e5eadca17f4031ab9208b37ebe4b 672 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 648 29.851 T 06-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 SMD11_RS25095 da00e5eadca17f4031ab9208b37ebe4b 672 SUPERFAMILY SSF47781 538 650 2.7E-20 T 06-07-2017 IPR010994 RuvA domain 2-like SMD11_RS06460 9756d77b039e3aa2588f375c06978814 605 SUPERFAMILY SSF55785 14 64 2.86E-7 T 06-07-2017 IPR000014 PAS domain SMD11_RS06460 9756d77b039e3aa2588f375c06978814 605 Gene3D G3DSA:3.30.450.20 9 61 1.2E-7 T 06-07-2017 SMD11_RS06460 9756d77b039e3aa2588f375c06978814 605 SUPERFAMILY SSF81606 284 463 3.14E-10 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS06460 9756d77b039e3aa2588f375c06978814 605 SMART SM00331 255 467 4.8E-28 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS06460 9756d77b039e3aa2588f375c06978814 605 Gene3D G3DSA:3.60.40.10 390 463 4.5E-4 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS06460 9756d77b039e3aa2588f375c06978814 605 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 282 466 1.8E-43 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS11145 fcfc7e84dc5d841f36d380842b0de9d5 312 SUPERFAMILY SSF88659 226 308 1.87E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11145 fcfc7e84dc5d841f36d380842b0de9d5 312 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 113 126 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11145 fcfc7e84dc5d841f36d380842b0de9d5 312 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 83 306 1.4E-87 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11145 fcfc7e84dc5d841f36d380842b0de9d5 312 Gene3D G3DSA:1.10.10.10 157 212 2.2E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11145 fcfc7e84dc5d841f36d380842b0de9d5 312 PRINTS PR00046 Major sigma-70 factor signature 261 273 5.5E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11145 fcfc7e84dc5d841f36d380842b0de9d5 312 PRINTS PR00046 Major sigma-70 factor signature 278 293 5.5E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11145 fcfc7e84dc5d841f36d380842b0de9d5 312 PRINTS PR00046 Major sigma-70 factor signature 113 126 5.5E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11145 fcfc7e84dc5d841f36d380842b0de9d5 312 Pfam PF04539 Sigma-70 region 3 168 225 2.4E-12 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11145 fcfc7e84dc5d841f36d380842b0de9d5 312 SUPERFAMILY SSF88946 50 158 1.22E-32 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11145 fcfc7e84dc5d841f36d380842b0de9d5 312 SUPERFAMILY SSF88659 162 239 1.26E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11145 fcfc7e84dc5d841f36d380842b0de9d5 312 Gene3D G3DSA:1.10.601.10 72 156 1.8E-26 T 06-07-2017 SMD11_RS11145 fcfc7e84dc5d841f36d380842b0de9d5 312 Pfam PF04542 Sigma-70 region 2 89 158 1.7E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11145 fcfc7e84dc5d841f36d380842b0de9d5 312 Pfam PF04545 Sigma-70, region 4 259 305 3.8E-17 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11145 fcfc7e84dc5d841f36d380842b0de9d5 312 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 85 306 1.2E-32 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11145 fcfc7e84dc5d841f36d380842b0de9d5 312 Gene3D G3DSA:1.10.10.10 254 305 8.0E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27090 2dc97bb7bdb1ca1d77f97e1d42df7f13 164 Gene3D G3DSA:3.30.530.20 14 158 4.1E-15 T 06-07-2017 IPR023393 START-like domain SMD11_RS27090 2dc97bb7bdb1ca1d77f97e1d42df7f13 164 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 18 141 2.6E-10 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase SMD11_RS27090 2dc97bb7bdb1ca1d77f97e1d42df7f13 164 SUPERFAMILY SSF55961 16 157 1.1E-15 T 06-07-2017 SMD11_RS22560 39fe88b3ea0dd260ca6bf370883dc3c2 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 5 278 5.4E-86 T 06-07-2017 IPR003797 DegV SMD11_RS22560 39fe88b3ea0dd260ca6bf370883dc3c2 281 Gene3D G3DSA:3.30.1180.10 156 280 9.3E-43 T 06-07-2017 SMD11_RS22560 39fe88b3ea0dd260ca6bf370883dc3c2 281 Gene3D G3DSA:3.40.50.10170 5 150 4.8E-44 T 06-07-2017 SMD11_RS22560 39fe88b3ea0dd260ca6bf370883dc3c2 281 SUPERFAMILY SSF82549 5 280 2.04E-76 T 06-07-2017 SMD11_RS22560 39fe88b3ea0dd260ca6bf370883dc3c2 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 280 9.0E-85 T 06-07-2017 IPR003797 DegV SMD11_RS09485 a75514a1c3e7884d4c4da9e1167f7e5c 569 SUPERFAMILY SSF161098 303 563 1.18E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS09485 a75514a1c3e7884d4c4da9e1167f7e5c 569 SUPERFAMILY SSF161098 27 285 4.45E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS09485 a75514a1c3e7884d4c4da9e1167f7e5c 569 Gene3D G3DSA:1.10.3720.10 32 286 1.7E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS09485 a75514a1c3e7884d4c4da9e1167f7e5c 569 Gene3D G3DSA:1.10.3720.10 309 564 6.3E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS09485 a75514a1c3e7884d4c4da9e1167f7e5c 569 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 382 553 3.2E-7 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS09485 a75514a1c3e7884d4c4da9e1167f7e5c 569 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 284 7.1E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS18875 a9b5c413a9ca4841ca41a094cd3f2070 700 SUPERFAMILY SSF89372 370 650 2.09E-18 T 06-07-2017 SMD11_RS18875 a9b5c413a9ca4841ca41a094cd3f2070 700 SUPERFAMILY SSF102588 59 131 6.15E-17 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD11_RS18875 a9b5c413a9ca4841ca41a094cd3f2070 700 SUPERFAMILY SSF102588 161 321 6.15E-17 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD11_RS18875 a9b5c413a9ca4841ca41a094cd3f2070 700 Gene3D G3DSA:3.40.50.10320 59 159 1.2E-20 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD11_RS18875 a9b5c413a9ca4841ca41a094cd3f2070 700 Gene3D G3DSA:3.40.50.10320 204 292 1.2E-20 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD11_RS18875 a9b5c413a9ca4841ca41a094cd3f2070 700 Pfam PF02585 GlcNAc-PI de-N-acetylase 60 272 1.1E-22 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SMD11_RS03065 cefeabad47fa7c2a442eab764ffb45ed 293 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 169 285 6.7E-15 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 SMD11_RS03065 cefeabad47fa7c2a442eab764ffb45ed 293 SUPERFAMILY SSF48179 169 287 1.59E-23 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS03065 cefeabad47fa7c2a442eab764ffb45ed 293 PIRSF PIRSF000103 1 292 9.3E-76 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD11_RS03065 cefeabad47fa7c2a442eab764ffb45ed 293 Gene3D G3DSA:3.40.50.720 7 162 1.1E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03065 cefeabad47fa7c2a442eab764ffb45ed 293 Gene3D G3DSA:1.10.1040.10 169 287 8.7E-27 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS03065 cefeabad47fa7c2a442eab764ffb45ed 293 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 8 160 8.6E-35 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD11_RS03065 cefeabad47fa7c2a442eab764ffb45ed 293 SUPERFAMILY SSF51735 7 163 8.68E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS16835 6957c3072fa570f8b8202bc545101f0a 576 SUPERFAMILY SSF56112 112 248 1.16E-13 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS16835 6957c3072fa570f8b8202bc545101f0a 576 Gene3D G3DSA:2.60.120.260 430 546 6.8E-4 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS16835 6957c3072fa570f8b8202bc545101f0a 576 Gene3D G3DSA:1.10.510.10 122 210 7.9E-9 T 06-07-2017 SMD11_RS24075 842ed4e25951e52800892518175b3306 593 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SMD11_RS24075 842ed4e25951e52800892518175b3306 593 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 156 185 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SMD11_RS24075 842ed4e25951e52800892518175b3306 593 SUPERFAMILY SSF52777 343 584 6.23E-78 T 06-07-2017 SMD11_RS24075 842ed4e25951e52800892518175b3306 593 SUPERFAMILY SSF51230 1 96 8.77E-27 T 06-07-2017 IPR011053 Single hybrid motif SMD11_RS24075 842ed4e25951e52800892518175b3306 593 Pfam PF00364 Biotin-requiring enzyme 5 76 7.5E-21 T 06-07-2017 IPR000089 Biotin/lipoyl attachment SMD11_RS24075 842ed4e25951e52800892518175b3306 593 Pfam PF00364 Biotin-requiring enzyme 133 205 3.7E-20 T 06-07-2017 IPR000089 Biotin/lipoyl attachment SMD11_RS24075 842ed4e25951e52800892518175b3306 593 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 593 1.1E-226 T 06-07-2017 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 SMD11_RS24075 842ed4e25951e52800892518175b3306 593 Gene3D G3DSA:2.40.50.100 132 225 1.5E-29 T 06-07-2017 SMD11_RS24075 842ed4e25951e52800892518175b3306 593 Gene3D G3DSA:2.40.50.100 1 96 5.7E-30 T 06-07-2017 SMD11_RS24075 842ed4e25951e52800892518175b3306 593 Gene3D G3DSA:3.30.559.10 350 585 6.8E-77 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 SMD11_RS24075 842ed4e25951e52800892518175b3306 593 SUPERFAMILY SSF51230 132 225 2.09E-26 T 06-07-2017 IPR011053 Single hybrid motif SMD11_RS24075 842ed4e25951e52800892518175b3306 593 SUPERFAMILY SSF47005 281 325 3.4E-11 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD11_RS24075 842ed4e25951e52800892518175b3306 593 Gene3D G3DSA:4.10.320.10 285 332 6.4E-17 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD11_RS24075 842ed4e25951e52800892518175b3306 593 Pfam PF02817 e3 binding domain 289 321 8.0E-13 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD11_RS24075 842ed4e25951e52800892518175b3306 593 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 357 585 2.9E-72 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD11_RS34230 fe4861a2d535172a5109a39589f60f73 151 SUPERFAMILY SSF64288 25 142 8.17E-15 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS34230 fe4861a2d535172a5109a39589f60f73 151 Pfam PF07702 UTRA domain 30 141 6.2E-12 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS34230 fe4861a2d535172a5109a39589f60f73 151 Gene3D G3DSA:3.40.1410.10 26 142 7.2E-17 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS15690 fac1ed73853349e7294c7b3f2bac37ab 219 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 39 202 1.5E-16 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD11_RS15690 fac1ed73853349e7294c7b3f2bac37ab 219 SUPERFAMILY SSF48498 46 205 1.06E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS15690 fac1ed73853349e7294c7b3f2bac37ab 219 Gene3D G3DSA:1.10.357.10 1 206 6.1E-41 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS00375 c88bee7d0156c41d1374653b5706145a 211 Gene3D G3DSA:1.10.357.10 61 190 4.5E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS00375 c88bee7d0156c41d1374653b5706145a 211 SUPERFAMILY SSF46689 8 78 3.44E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS00375 c88bee7d0156c41d1374653b5706145a 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 63 1.6E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00375 c88bee7d0156c41d1374653b5706145a 211 Gene3D G3DSA:1.10.10.60 9 60 5.2E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS25710 acebcf080b4cd1fa73d48299fc13fb4f 761 SUPERFAMILY SSF48452 497 661 1.59E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS25710 acebcf080b4cd1fa73d48299fc13fb4f 761 Gene3D G3DSA:1.25.40.10 488 551 5.2E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS25710 acebcf080b4cd1fa73d48299fc13fb4f 761 Gene3D G3DSA:1.25.40.10 620 659 5.2E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 Gene3D G3DSA:3.40.50.150 844 926 1.1E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 Gene3D G3DSA:3.40.50.150 964 1128 1.1E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 SUPERFAMILY SSF52980 31 117 1.5E-7 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 Gene3D G3DSA:3.40.50.300 140 345 8.1E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 SUPERFAMILY SSF52540 255 346 1.13E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 SUPERFAMILY SSF52540 157 215 1.13E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 SUPERFAMILY SSF52540 452 573 1.13E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 Pfam PF02384 N-6 DNA Methylase 822 1007 6.6E-5 T 06-07-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 SMART SM00487 136 374 9.5E-15 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 Pfam PF00271 Helicase conserved C-terminal domain 452 563 1.1E-5 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 Pfam PF04851 Type III restriction enzyme, res subunit 138 344 9.5E-27 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 SMART SM00490 467 564 4.5E-4 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 842 858 1.2E-5 T 06-07-2017 SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 877 891 1.2E-5 T 06-07-2017 SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 981 993 1.2E-5 T 06-07-2017 SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 Pfam PF13156 Restriction endonuclease 7 122 1.8E-46 T 06-07-2017 SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 SUPERFAMILY SSF53335 755 929 1.77E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 SUPERFAMILY SSF53335 958 1145 1.77E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 984 990 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMD11_RS15670 ac61d99da3a0b52cbd47cb007177734b 1590 Gene3D G3DSA:3.40.50.300 450 573 6.1E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS06945 120063aca24d9537f711f42683250602 298 SUPERFAMILY SSF55620 3 129 2.54E-40 T 06-07-2017 SMD11_RS06945 120063aca24d9537f711f42683250602 298 Gene3D G3DSA:3.10.270.10 4 288 5.4E-106 T 06-07-2017 SMD11_RS06945 120063aca24d9537f711f42683250602 298 PRINTS PR00093 Uricase signature 85 98 4.5E-18 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD11_RS06945 120063aca24d9537f711f42683250602 298 PRINTS PR00093 Uricase signature 10 21 4.5E-18 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD11_RS06945 120063aca24d9537f711f42683250602 298 PRINTS PR00093 Uricase signature 146 162 4.5E-18 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD11_RS06945 120063aca24d9537f711f42683250602 298 PRINTS PR00093 Uricase signature 49 63 4.5E-18 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD11_RS06945 120063aca24d9537f711f42683250602 298 PRINTS PR00093 Uricase signature 162 174 4.5E-18 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD11_RS06945 120063aca24d9537f711f42683250602 298 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 176 283 2.0E-42 T 06-07-2017 SMD11_RS06945 120063aca24d9537f711f42683250602 298 TIGRFAM TIGR03383 urate_oxi: urate oxidase 4 283 8.9E-105 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD11_RS06945 120063aca24d9537f711f42683250602 298 SUPERFAMILY SSF55620 137 287 3.22E-56 T 06-07-2017 SMD11_RS06945 120063aca24d9537f711f42683250602 298 PIRSF PIRSF000241 2 290 3.7E-100 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD11_RS06945 120063aca24d9537f711f42683250602 298 Pfam PF01014 Uricase 140 278 3.4E-31 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD11_RS06945 120063aca24d9537f711f42683250602 298 Pfam PF01014 Uricase 8 131 7.0E-18 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 SMD11_RS02695 b7b9a57c334c4b7ba890178dc94a49f4 311 SUPERFAMILY SSF161098 102 295 1.07E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS02695 b7b9a57c334c4b7ba890178dc94a49f4 311 Gene3D G3DSA:1.10.3720.10 100 306 6.8E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS02695 b7b9a57c334c4b7ba890178dc94a49f4 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 307 2.0E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS14870 641b203e504e3660d0127483f61f8b79 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14870 641b203e504e3660d0127483f61f8b79 225 Gene3D G3DSA:1.10.10.10 125 218 8.0E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14870 641b203e504e3660d0127483f61f8b79 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 211 2.1E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14870 641b203e504e3660d0127483f61f8b79 225 Pfam PF00072 Response regulator receiver domain 5 116 2.4E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS14870 641b203e504e3660d0127483f61f8b79 225 Gene3D G3DSA:3.40.50.2300 1 124 1.4E-37 T 06-07-2017 SMD11_RS14870 641b203e504e3660d0127483f61f8b79 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 4.8E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14870 641b203e504e3660d0127483f61f8b79 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 4.8E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14870 641b203e504e3660d0127483f61f8b79 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 4.8E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14870 641b203e504e3660d0127483f61f8b79 225 SMART SM00421 154 211 1.1E-25 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14870 641b203e504e3660d0127483f61f8b79 225 SUPERFAMILY SSF52172 1 135 3.27E-33 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS14870 641b203e504e3660d0127483f61f8b79 225 SUPERFAMILY SSF46894 148 217 5.1E-23 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS14870 641b203e504e3660d0127483f61f8b79 225 SMART SM00448 3 116 5.4E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS23610 55a954515a514b2e54c5338ef649838d 346 Pfam PF01497 Periplasmic binding protein 93 319 4.3E-29 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD11_RS23610 55a954515a514b2e54c5338ef649838d 346 Gene3D G3DSA:3.40.50.1980 72 189 8.1E-36 T 06-07-2017 SMD11_RS23610 55a954515a514b2e54c5338ef649838d 346 Gene3D G3DSA:3.40.50.1980 190 345 3.4E-33 T 06-07-2017 SMD11_RS23610 55a954515a514b2e54c5338ef649838d 346 SUPERFAMILY SSF53807 74 340 1.84E-61 T 06-07-2017 SMD11_RS13520 6d033ae288b3521c95ac99e771e45bce 221 Gene3D G3DSA:1.10.10.10 152 211 2.7E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13520 6d033ae288b3521c95ac99e771e45bce 221 SMART SM00448 2 114 4.2E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS13520 6d033ae288b3521c95ac99e771e45bce 221 Pfam PF00072 Response regulator receiver domain 4 115 5.6E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS13520 6d033ae288b3521c95ac99e771e45bce 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13520 6d033ae288b3521c95ac99e771e45bce 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 1.5E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13520 6d033ae288b3521c95ac99e771e45bce 221 SUPERFAMILY SSF46894 143 212 3.74E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS13520 6d033ae288b3521c95ac99e771e45bce 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 4.2E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13520 6d033ae288b3521c95ac99e771e45bce 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 4.2E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13520 6d033ae288b3521c95ac99e771e45bce 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 4.2E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13520 6d033ae288b3521c95ac99e771e45bce 221 SUPERFAMILY SSF52172 2 129 2.56E-30 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS13520 6d033ae288b3521c95ac99e771e45bce 221 Gene3D G3DSA:3.40.50.2300 2 151 2.8E-36 T 06-07-2017 SMD11_RS13520 6d033ae288b3521c95ac99e771e45bce 221 SMART SM00421 149 206 3.9E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS29995 7a2bc1d5953eb8a08f33e0cef07d4b26 338 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 27 45 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 SMD11_RS29995 7a2bc1d5953eb8a08f33e0cef07d4b26 338 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 3 293 1.6E-56 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS29995 7a2bc1d5953eb8a08f33e0cef07d4b26 338 Gene3D G3DSA:3.40.50.1100 1 36 2.6E-45 T 06-07-2017 SMD11_RS29995 7a2bc1d5953eb8a08f33e0cef07d4b26 338 Gene3D G3DSA:3.40.50.1100 150 310 2.6E-45 T 06-07-2017 SMD11_RS29995 7a2bc1d5953eb8a08f33e0cef07d4b26 338 Gene3D G3DSA:3.40.50.1100 37 144 8.3E-27 T 06-07-2017 SMD11_RS29995 7a2bc1d5953eb8a08f33e0cef07d4b26 338 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 1 308 4.6E-123 T 06-07-2017 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA SMD11_RS29995 7a2bc1d5953eb8a08f33e0cef07d4b26 338 SUPERFAMILY SSF53686 2 312 3.4E-72 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS11050 212e1f5020a7a7e72f244a945a101414 1273 SUPERFAMILY SSF52518 455 862 2.06E-88 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS11050 212e1f5020a7a7e72f244a945a101414 1273 Gene3D G3DSA:3.30.559.10 143 387 8.9E-51 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 SMD11_RS11050 212e1f5020a7a7e72f244a945a101414 1273 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1123 1271 1.2E-45 T 06-07-2017 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 SMD11_RS11050 212e1f5020a7a7e72f244a945a101414 1273 Pfam PF00676 Dehydrogenase E1 component 540 862 5.2E-56 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 SMD11_RS11050 212e1f5020a7a7e72f244a945a101414 1273 Gene3D G3DSA:3.40.50.970 928 1129 2.5E-23 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS11050 212e1f5020a7a7e72f244a945a101414 1273 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 417 1271 0.0 T 06-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 SMD11_RS11050 212e1f5020a7a7e72f244a945a101414 1273 SMART SM00861 925 1118 1.7E-55 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS11050 212e1f5020a7a7e72f244a945a101414 1273 SUPERFAMILY SSF52777 141 387 1.02E-54 T 06-07-2017 SMD11_RS11050 212e1f5020a7a7e72f244a945a101414 1273 Pfam PF02779 Transketolase, pyrimidine binding domain 924 1117 1.7E-59 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS11050 212e1f5020a7a7e72f244a945a101414 1273 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 157 387 1.5E-49 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD11_RS11050 212e1f5020a7a7e72f244a945a101414 1273 Gene3D G3DSA:3.40.50.970 497 862 4.6E-80 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS11050 212e1f5020a7a7e72f244a945a101414 1273 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 26 61 2.3E-11 T 06-07-2017 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 SMD11_RS11050 212e1f5020a7a7e72f244a945a101414 1273 PIRSF PIRSF000157 12 1273 0.0 T 06-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 SMD11_RS11050 212e1f5020a7a7e72f244a945a101414 1273 SUPERFAMILY SSF52518 915 1123 1.35E-47 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS08900 ddf56bf7f4586c70ae57cd94d0c45e0a 479 SUPERFAMILY SSF55874 301 464 8.77E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08900 ddf56bf7f4586c70ae57cd94d0c45e0a 479 Gene3D G3DSA:1.10.287.130 239 307 5.1E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS08900 ddf56bf7f4586c70ae57cd94d0c45e0a 479 Gene3D G3DSA:3.30.565.10 316 465 1.9E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08900 ddf56bf7f4586c70ae57cd94d0c45e0a 479 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 462 7.7E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08900 ddf56bf7f4586c70ae57cd94d0c45e0a 479 SMART SM00388 249 312 8.5E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS08900 ddf56bf7f4586c70ae57cd94d0c45e0a 479 Pfam PF00672 HAMP domain 180 244 8.6E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS08900 ddf56bf7f4586c70ae57cd94d0c45e0a 479 SUPERFAMILY SSF47384 232 310 7.46E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS08900 ddf56bf7f4586c70ae57cd94d0c45e0a 479 SMART SM00304 195 248 4.2E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS08900 ddf56bf7f4586c70ae57cd94d0c45e0a 479 SMART SM00387 355 465 6.8E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08900 ddf56bf7f4586c70ae57cd94d0c45e0a 479 SUPERFAMILY SSF158472 196 246 4.32E-7 T 06-07-2017 SMD11_RS08900 ddf56bf7f4586c70ae57cd94d0c45e0a 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 406 2.2E-5 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS08900 ddf56bf7f4586c70ae57cd94d0c45e0a 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 443 2.2E-5 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS08900 ddf56bf7f4586c70ae57cd94d0c45e0a 479 Pfam PF00512 His Kinase A (phospho-acceptor) domain 250 311 5.9E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS19870 ae0efb544f83ad9d6e2f44272e2bf42d 211 Pfam PF13302 Acetyltransferase (GNAT) domain 14 161 5.3E-16 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS19870 ae0efb544f83ad9d6e2f44272e2bf42d 211 SUPERFAMILY SSF55729 8 185 1.14E-41 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS19870 ae0efb544f83ad9d6e2f44272e2bf42d 211 Gene3D G3DSA:3.40.630.30 4 189 4.5E-58 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS17025 9536fde2dc5c0a11c841e2453e37d32e 236 Gene3D G3DSA:2.40.260.10 76 223 1.1E-24 T 06-07-2017 IPR023365 Sortase domain SMD11_RS17025 9536fde2dc5c0a11c841e2453e37d32e 236 SUPERFAMILY SSF63817 74 223 4.05E-29 T 06-07-2017 IPR023365 Sortase domain SMD11_RS17025 9536fde2dc5c0a11c841e2453e37d32e 236 TIGRFAM TIGR01076 sortase_fam: sortase 82 218 9.9E-12 T 06-07-2017 IPR005754 Sortase family SMD11_RS17025 9536fde2dc5c0a11c841e2453e37d32e 236 Pfam PF04203 Sortase family 85 219 9.2E-26 T 06-07-2017 IPR005754 Sortase family SMD11_RS04175 a04c302d4be727043aadc5b336f73ea2 410 Gene3D G3DSA:1.20.1250.20 28 200 5.7E-16 T 06-07-2017 SMD11_RS04175 a04c302d4be727043aadc5b336f73ea2 410 SUPERFAMILY SSF103473 243 408 8.76E-38 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS04175 a04c302d4be727043aadc5b336f73ea2 410 SUPERFAMILY SSF103473 25 208 8.76E-38 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS04175 a04c302d4be727043aadc5b336f73ea2 410 Gene3D G3DSA:1.20.1250.20 257 408 4.3E-14 T 06-07-2017 SMD11_RS04175 a04c302d4be727043aadc5b336f73ea2 410 Pfam PF07690 Major Facilitator Superfamily 29 401 1.1E-25 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS21150 e9cca3bc953f55699bcfa7869eb10aa3 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 7.4E-10 T 06-07-2017 SMD11_RS21150 e9cca3bc953f55699bcfa7869eb10aa3 155 Pfam PF01037 Lrp/AsnC ligand binding domain 72 138 1.1E-13 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS21150 e9cca3bc953f55699bcfa7869eb10aa3 155 SUPERFAMILY SSF46785 2 63 1.65E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21150 e9cca3bc953f55699bcfa7869eb10aa3 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.6E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS21150 e9cca3bc953f55699bcfa7869eb10aa3 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.6E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS21150 e9cca3bc953f55699bcfa7869eb10aa3 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.6E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS21150 e9cca3bc953f55699bcfa7869eb10aa3 155 SUPERFAMILY SSF54909 63 148 7.37E-17 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS21150 e9cca3bc953f55699bcfa7869eb10aa3 155 SMART SM00344 3 109 2.0E-28 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD11_RS21150 e9cca3bc953f55699bcfa7869eb10aa3 155 Gene3D G3DSA:3.30.70.920 56 142 6.1E-19 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS21150 e9cca3bc953f55699bcfa7869eb10aa3 155 Gene3D G3DSA:1.10.10.10 2 53 2.8E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08145 aa31888fcf78aa827f939d536b4ab53e 364 SUPERFAMILY SSF56645 5 209 7.59E-53 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS08145 aa31888fcf78aa827f939d536b4ab53e 364 Gene3D G3DSA:2.40.110.10 107 198 1.6E-31 T 06-07-2017 SMD11_RS08145 aa31888fcf78aa827f939d536b4ab53e 364 SUPERFAMILY SSF47203 217 360 5.8E-32 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS08145 aa31888fcf78aa827f939d536b4ab53e 364 Gene3D G3DSA:1.20.140.10 199 361 3.8E-36 T 06-07-2017 SMD11_RS08145 aa31888fcf78aa827f939d536b4ab53e 364 Gene3D G3DSA:1.10.540.10 7 104 1.0E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS08145 aa31888fcf78aa827f939d536b4ab53e 364 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 216 358 2.4E-28 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS08145 aa31888fcf78aa827f939d536b4ab53e 364 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 104 3.9E-9 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS08145 aa31888fcf78aa827f939d536b4ab53e 364 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 107 197 2.9E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS00305 23881fdef42004d5431fe69f9e394fb8 219 Gene3D G3DSA:1.10.340.30 39 148 1.1E-6 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD11_RS00305 23881fdef42004d5431fe69f9e394fb8 219 SUPERFAMILY SSF48150 39 198 1.4E-11 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 241 289 2.9E-5 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 SMART SM00926 237 291 3.9E-7 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 SUPERFAMILY SSF53706 228 712 2.3E-78 T 06-07-2017 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 SUPERFAMILY SSF50692 724 799 9.27E-6 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 Pfam PF01568 Molydopterin dinucleotide binding domain 744 816 1.4E-5 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 Gene3D G3DSA:3.40.50.740 559 698 1.6E-41 T 06-07-2017 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 Gene3D G3DSA:3.40.50.740 403 440 1.6E-41 T 06-07-2017 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 Gene3D G3DSA:3.40.50.740 294 362 1.6E-41 T 06-07-2017 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 Gene3D G3DSA:2.20.25.90 241 291 3.4E-11 T 06-07-2017 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 23 673 1.5E-186 T 06-07-2017 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 20 94 2.5E-18 T 06-07-2017 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 SUPERFAMILY SSF54292 21 93 1.26E-18 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 50 67 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 167 177 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 Gene3D G3DSA:3.10.20.30 21 75 7.1E-5 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 SUPERFAMILY SSF54862 97 232 1.93E-30 T 06-07-2017 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 SMART SM00929 104 144 1.3E-18 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 104 140 7.1E-16 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 Pfam PF00384 Molybdopterin oxidoreductase 294 439 4.7E-9 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 Pfam PF00384 Molybdopterin oxidoreductase 525 658 4.3E-8 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18565 ca7eb2cc5e72404e111ff34e81b45a86 834 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 119 131 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS10295 59f7233be0fefe7adfb8317061cb7430 420 Gene3D G3DSA:3.90.1150.10 284 417 3.6E-47 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS10295 59f7233be0fefe7adfb8317061cb7430 420 PIRSF PIRSF000412 1 415 4.1E-159 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMD11_RS10295 59f7233be0fefe7adfb8317061cb7430 420 Pfam PF00464 Serine hydroxymethyltransferase 9 389 5.5E-165 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMD11_RS10295 59f7233be0fefe7adfb8317061cb7430 420 Gene3D G3DSA:3.40.640.10 37 283 3.3E-106 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS10295 59f7233be0fefe7adfb8317061cb7430 420 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 50.788 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMD11_RS10295 59f7233be0fefe7adfb8317061cb7430 420 SUPERFAMILY SSF53383 4 417 4.73E-173 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS10295 59f7233be0fefe7adfb8317061cb7430 420 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 06-07-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMD11_RS02330 17b042be16e7faee6f97bb24922318d1 345 Gene3D G3DSA:3.40.50.150 105 343 5.0E-65 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS02330 17b042be16e7faee6f97bb24922318d1 345 SUPERFAMILY SSF53335 103 342 2.05E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS02330 17b042be16e7faee6f97bb24922318d1 345 Gene3D G3DSA:1.10.10.10 17 104 1.5E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02330 17b042be16e7faee6f97bb24922318d1 345 Pfam PF00891 O-methyltransferase 111 329 4.7E-38 T 06-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 SMD11_RS02330 17b042be16e7faee6f97bb24922318d1 345 SUPERFAMILY SSF46785 19 99 3.56E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02330 17b042be16e7faee6f97bb24922318d1 345 PIRSF PIRSF005739 2 344 8.8E-49 T 06-07-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 SMD11_RS26920 b4c3432e86cd02b0e9d475098adac47d 182 SUPERFAMILY SSF48498 85 174 1.4E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS26920 b4c3432e86cd02b0e9d475098adac47d 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 52 8.9E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS26920 b4c3432e86cd02b0e9d475098adac47d 182 Gene3D G3DSA:1.10.357.10 5 176 1.2E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS26920 b4c3432e86cd02b0e9d475098adac47d 182 SUPERFAMILY SSF46689 4 65 5.49E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS20515 5b371d9ae24169ef2811391bb76372b9 389 Gene3D G3DSA:3.20.20.140 70 365 2.7E-44 T 06-07-2017 SMD11_RS20515 5b371d9ae24169ef2811391bb76372b9 389 Gene3D G3DSA:2.30.40.10 27 69 8.6E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS20515 5b371d9ae24169ef2811391bb76372b9 389 SUPERFAMILY SSF51338 348 386 2.95E-14 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS20515 5b371d9ae24169ef2811391bb76372b9 389 SUPERFAMILY SSF51338 22 65 2.95E-14 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS20515 5b371d9ae24169ef2811391bb76372b9 389 Hamap MF_00372 Imidazolonepropionase [hutI]. 3 388 43.286 T 06-07-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD11_RS20515 5b371d9ae24169ef2811391bb76372b9 389 TIGRFAM TIGR01224 hutI: imidazolonepropionase 28 385 2.2E-110 T 06-07-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD11_RS20515 5b371d9ae24169ef2811391bb76372b9 389 Pfam PF01979 Amidohydrolase family 248 363 6.4E-17 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 SMD11_RS20515 5b371d9ae24169ef2811391bb76372b9 389 SUPERFAMILY SSF51556 64 347 3.16E-69 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS02295 3cbcb3f96090f50aa76def6c27f27020 236 Hamap MF_00042 Ribonuclease H [rnhA]. 2 154 32.757 T 06-07-2017 IPR022892 Ribonuclease H GO:0004523 SMD11_RS02295 3cbcb3f96090f50aa76def6c27f27020 236 Gene3D G3DSA:3.30.420.10 2 148 1.6E-44 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS02295 3cbcb3f96090f50aa76def6c27f27020 236 SUPERFAMILY SSF53098 4 147 4.05E-40 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS02295 3cbcb3f96090f50aa76def6c27f27020 236 Pfam PF00075 RNase H 6 145 1.9E-28 T 06-07-2017 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 SUPERFAMILY SSF55048 673 734 3.4E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 285 7.3E-86 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 413 504 7.7E-15 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 552 841 8.2E-120 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 SMART SM00825 Beta-ketoacyl synthase 37 463 6.5E-216 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 Gene3D G3DSA:3.40.47.10 298 463 8.9E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 410 1.9E-45 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 SUPERFAMILY SSF51735 1168 1327 1.46E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1654 1669 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 Gene3D G3DSA:3.30.70.250 673 734 3.1E-6 T 06-07-2017 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 SUPERFAMILY SSF47336 1620 1702 8.24E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 Gene3D G3DSA:3.40.366.10 735 855 5.0E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 Gene3D G3DSA:3.40.366.10 540 669 5.0E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 Gene3D G3DSA:1.10.1200.10 1626 1699 3.0E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 SUPERFAMILY SSF52151 549 674 1.73E-73 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 SUPERFAMILY SSF52151 735 834 1.73E-73 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 SMART SM00826 908 1063 4.5E-49 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 SUPERFAMILY SSF51735 1341 1573 1.14E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 Pfam PF08659 KR domain 1345 1521 5.2E-57 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1345 1523 1.1E-54 T 06-07-2017 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 SMART SM01294 1628 1695 4.9E-6 T 06-07-2017 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 SUPERFAMILY SSF53901 32 409 6.51E-103 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 SMART SM00823 Phosphopantetheine attachment site 1627 1699 1.2E-32 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 Gene3D G3DSA:3.40.50.720 1344 1525 1.5E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 Pfam PF00550 Phosphopantetheine attachment site 1629 1695 3.2E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 Pfam PF14765 Polyketide synthase dehydratase 908 1157 8.3E-25 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 Pfam PF00698 Acyl transferase domain 552 860 4.9E-58 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS32320 ff26d81d7e88026308a6375aa7dc5d81 1784 Gene3D G3DSA:3.40.47.10 37 297 2.6E-89 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS25185 5d0118cbeeb4e183ec418376eec78808 346 SUPERFAMILY SSF51556 192 313 8.16E-6 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS25185 5d0118cbeeb4e183ec418376eec78808 346 SUPERFAMILY SSF51556 90 146 8.16E-6 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS25185 5d0118cbeeb4e183ec418376eec78808 346 Gene3D G3DSA:3.20.20.140 5 344 8.2E-62 T 06-07-2017 SMD11_RS10975 9548b1186b360cb43e766e67250efed0 143 Pfam PF13463 Winged helix DNA-binding domain 47 100 1.4E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS10975 9548b1186b360cb43e766e67250efed0 143 Gene3D G3DSA:1.10.10.10 8 139 8.2E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS10975 9548b1186b360cb43e766e67250efed0 143 SUPERFAMILY SSF46785 7 140 6.72E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS10975 9548b1186b360cb43e766e67250efed0 143 SMART SM00347 27 127 5.7E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS23895 f9c44604489a3d2087d8af93faf94fd1 324 Gene3D G3DSA:1.10.3720.10 93 320 6.0E-63 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS23895 f9c44604489a3d2087d8af93faf94fd1 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 315 1.1E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS23895 f9c44604489a3d2087d8af93faf94fd1 324 SUPERFAMILY SSF161098 82 311 9.81E-60 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS23895 f9c44604489a3d2087d8af93faf94fd1 324 Gene3D G3DSA:1.20.58.370 25 58 9.9E-4 T 06-07-2017 SMD11_RS29805 0e51836c8d0d92cbfe6027459f703463 405 Gene3D G3DSA:3.40.47.10 3 258 7.1E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29805 0e51836c8d0d92cbfe6027459f703463 405 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 362 1.8E-24 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS29805 0e51836c8d0d92cbfe6027459f703463 405 SUPERFAMILY SSF53901 212 402 5.5E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29805 0e51836c8d0d92cbfe6027459f703463 405 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 243 3.7E-46 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS29805 0e51836c8d0d92cbfe6027459f703463 405 SMART SM00825 Beta-ketoacyl synthase 5 405 4.9E-7 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS29805 0e51836c8d0d92cbfe6027459f703463 405 Gene3D G3DSA:3.40.47.10 271 404 5.0E-40 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29805 0e51836c8d0d92cbfe6027459f703463 405 SUPERFAMILY SSF53901 4 249 1.39E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS23255 91f495b5bd3c3130a78275d5f3d1d8a6 530 Gene3D G3DSA:1.20.1250.20 25 208 2.1E-32 T 06-07-2017 SMD11_RS23255 91f495b5bd3c3130a78275d5f3d1d8a6 530 Pfam PF07690 Major Facilitator Superfamily 31 423 8.2E-56 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS23255 91f495b5bd3c3130a78275d5f3d1d8a6 530 SUPERFAMILY SSF103473 12 210 1.7E-74 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS23255 91f495b5bd3c3130a78275d5f3d1d8a6 530 SUPERFAMILY SSF103473 492 517 1.7E-74 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS23255 91f495b5bd3c3130a78275d5f3d1d8a6 530 SUPERFAMILY SSF103473 262 433 1.7E-74 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS23255 91f495b5bd3c3130a78275d5f3d1d8a6 530 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 27 514 1.2E-91 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS23255 91f495b5bd3c3130a78275d5f3d1d8a6 530 Gene3D G3DSA:1.20.1250.20 282 434 1.0E-23 T 06-07-2017 SMD11_RS23255 91f495b5bd3c3130a78275d5f3d1d8a6 530 Gene3D G3DSA:1.20.1250.20 493 518 1.0E-23 T 06-07-2017 SMD11_RS21895 874a6f951184a6221988e272d0241ad9 705 Pfam PF12805 FUSC-like inner membrane protein yccS 79 190 7.6E-8 T 06-07-2017 IPR032692 Integral membrane protein YccS, N-terminal SMD11_RS21895 874a6f951184a6221988e272d0241ad9 705 Pfam PF13515 Fusaric acid resistance protein-like 392 513 4.3E-18 T 06-07-2017 SMD11_RS27940 bd65b76acae24cf4f8830fa0a3ebdd7d 434 Gene3D G3DSA:3.30.565.10 288 430 1.9E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS27940 bd65b76acae24cf4f8830fa0a3ebdd7d 434 Gene3D G3DSA:1.10.287.130 209 277 3.9E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS27940 bd65b76acae24cf4f8830fa0a3ebdd7d 434 SMART SM00388 217 281 1.0E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS27940 bd65b76acae24cf4f8830fa0a3ebdd7d 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 218 280 1.8E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS27940 bd65b76acae24cf4f8830fa0a3ebdd7d 434 SUPERFAMILY SSF55874 271 430 2.49E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS27940 bd65b76acae24cf4f8830fa0a3ebdd7d 434 SMART SM00304 163 216 8.2E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS27940 bd65b76acae24cf4f8830fa0a3ebdd7d 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 1.9E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS27940 bd65b76acae24cf4f8830fa0a3ebdd7d 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 429 1.9E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS27940 bd65b76acae24cf4f8830fa0a3ebdd7d 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 385 1.9E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS27940 bd65b76acae24cf4f8830fa0a3ebdd7d 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 410 1.9E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS27940 bd65b76acae24cf4f8830fa0a3ebdd7d 434 SUPERFAMILY SSF47384 200 280 1.02E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS27940 bd65b76acae24cf4f8830fa0a3ebdd7d 434 SMART SM00387 322 432 2.4E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS27940 bd65b76acae24cf4f8830fa0a3ebdd7d 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 429 3.3E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS27940 bd65b76acae24cf4f8830fa0a3ebdd7d 434 Pfam PF00672 HAMP domain 150 213 2.6E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS08085 1e718725b9401449fb3f216a6b08f196 292 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 5.3E-124 T 06-07-2017 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 SMD11_RS08085 1e718725b9401449fb3f216a6b08f196 292 SUPERFAMILY SSF53448 1 286 1.15E-84 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS08085 1e718725b9401449fb3f216a6b08f196 292 Gene3D G3DSA:3.90.550.10 1 266 3.3E-66 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS08085 1e718725b9401449fb3f216a6b08f196 292 Pfam PF00483 Nucleotidyl transferase 2 236 3.8E-59 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMD11_RS23950 f55a2c0014cd8eadf1238eb016f60672 185 Pfam PF00486 Transcriptional regulatory protein, C terminal 108 178 4.1E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS23950 f55a2c0014cd8eadf1238eb016f60672 185 SUPERFAMILY SSF46894 93 179 2.78E-26 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS23950 f55a2c0014cd8eadf1238eb016f60672 185 SMART SM00862 105 179 3.7E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS23950 f55a2c0014cd8eadf1238eb016f60672 185 Gene3D G3DSA:1.10.10.10 92 181 5.7E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS31130 437f99d4246d109281ff4b4deaea3996 237 SUPERFAMILY SSF49482 78 234 5.1E-47 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMD11_RS31130 437f99d4246d109281ff4b4deaea3996 237 Pfam PF00775 Dioxygenase 87 214 1.2E-17 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 SMD11_RS31130 437f99d4246d109281ff4b4deaea3996 237 Gene3D G3DSA:2.60.130.10 79 233 2.2E-44 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMD11_RS17525 1b69e27634cc113537b2f5f1744461da 596 Pfam PF15575 Immunity protein 49 385 592 2.0E-32 T 06-07-2017 IPR029074 Immunity protein 49 SMD11_RS17525 1b69e27634cc113537b2f5f1744461da 596 Pfam PF15575 Immunity protein 49 73 292 2.2E-21 T 06-07-2017 IPR029074 Immunity protein 49 SMD11_RS20650 03502e3906226419374f3a71c72fe669 250 Gene3D G3DSA:3.40.50.980 7 90 1.9E-8 T 06-07-2017 SMD11_RS20650 03502e3906226419374f3a71c72fe669 250 SUPERFAMILY SSF56801 3 248 2.09E-23 T 06-07-2017 SMD11_RS20650 03502e3906226419374f3a71c72fe669 250 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 11 246 4.0E-84 T 06-07-2017 IPR017523 Conserved hypothetical protein CHP03089 SMD11_RS20650 03502e3906226419374f3a71c72fe669 250 Pfam PF00501 AMP-binding enzyme 19 90 1.4E-6 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS12475 7e234d0f51a48d2a4a563db7491d38bf 186 Gene3D G3DSA:1.10.10.10 111 159 1.2E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12475 7e234d0f51a48d2a4a563db7491d38bf 186 Pfam PF04545 Sigma-70, region 4 111 158 7.4E-9 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS12475 7e234d0f51a48d2a4a563db7491d38bf 186 SUPERFAMILY SSF88659 110 159 5.79E-10 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS33565 476237fda8c6412103f9a35f4955ec09 204 SUPERFAMILY SSF52540 8 161 7.91E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS33565 476237fda8c6412103f9a35f4955ec09 204 Gene3D G3DSA:3.40.50.300 9 150 7.1E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05285 d6bc750facfd7ca4aac8a95904744f66 161 SUPERFAMILY SSF55874 59 155 5.63E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS05285 d6bc750facfd7ca4aac8a95904744f66 161 Gene3D G3DSA:3.30.565.10 38 155 1.3E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS05285 d6bc750facfd7ca4aac8a95904744f66 161 Pfam PF13581 Histidine kinase-like ATPase domain 36 151 6.6E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS20255 49a2803547a68f533bc9a211d84cbb8c 520 Gene3D G3DSA:3.30.200.20 3 79 4.2E-23 T 06-07-2017 SMD11_RS20255 49a2803547a68f533bc9a211d84cbb8c 520 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS20255 49a2803547a68f533bc9a211d84cbb8c 520 Pfam PF00069 Protein kinase domain 10 268 8.5E-42 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS20255 49a2803547a68f533bc9a211d84cbb8c 520 Gene3D G3DSA:1.10.510.10 80 270 5.7E-45 T 06-07-2017 SMD11_RS20255 49a2803547a68f533bc9a211d84cbb8c 520 SUPERFAMILY SSF48452 383 487 8.73E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS20255 49a2803547a68f533bc9a211d84cbb8c 520 SUPERFAMILY SSF56112 4 283 5.4E-74 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS20255 49a2803547a68f533bc9a211d84cbb8c 520 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS20255 49a2803547a68f533bc9a211d84cbb8c 520 SMART SM00220 10 276 3.4E-55 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS20255 49a2803547a68f533bc9a211d84cbb8c 520 Gene3D G3DSA:1.25.40.10 369 496 6.9E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS02355 195bd35a920eeec8ab0e2020a1105e32 381 Pfam PF08281 Sigma-70, region 4 98 148 7.5E-8 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS02355 195bd35a920eeec8ab0e2020a1105e32 381 SUPERFAMILY SSF88659 91 149 2.62E-8 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS02355 195bd35a920eeec8ab0e2020a1105e32 381 Gene3D G3DSA:1.10.1740.10 4 89 1.2E-11 T 06-07-2017 SMD11_RS02355 195bd35a920eeec8ab0e2020a1105e32 381 Gene3D G3DSA:1.10.10.10 92 148 2.3E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02355 195bd35a920eeec8ab0e2020a1105e32 381 SUPERFAMILY SSF88946 3 85 5.89E-12 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS02355 195bd35a920eeec8ab0e2020a1105e32 381 Pfam PF04542 Sigma-70 region 2 5 69 8.5E-9 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS02430 37b6c7aee21fc44632f33480edb5a979 316 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 294 310 5.1E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD11_RS02430 37b6c7aee21fc44632f33480edb5a979 316 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 279 294 5.1E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD11_RS02430 37b6c7aee21fc44632f33480edb5a979 316 SMART SM00342 227 310 7.5E-33 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS02430 37b6c7aee21fc44632f33480edb5a979 316 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 264 306 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD11_RS02430 37b6c7aee21fc44632f33480edb5a979 316 SUPERFAMILY SSF46689 210 261 1.88E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS02430 37b6c7aee21fc44632f33480edb5a979 316 SUPERFAMILY SSF46689 263 312 1.88E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS02430 37b6c7aee21fc44632f33480edb5a979 316 Gene3D G3DSA:1.10.10.60 209 263 3.4E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS02430 37b6c7aee21fc44632f33480edb5a979 316 Gene3D G3DSA:1.10.10.60 264 313 2.6E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS02430 37b6c7aee21fc44632f33480edb5a979 316 Pfam PF12852 Cupin 2 194 3.4E-47 T 06-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain SMD11_RS02430 37b6c7aee21fc44632f33480edb5a979 316 Pfam PF12833 Helix-turn-helix domain 233 311 4.8E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS06985 2b6f69a909fc14d46426850aa24aab8e 570 Gene3D G3DSA:3.40.50.970 355 553 2.3E-51 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS06985 2b6f69a909fc14d46426850aa24aab8e 570 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 387 544 6.8E-33 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMD11_RS06985 2b6f69a909fc14d46426850aa24aab8e 570 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 2 165 8.9E-55 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMD11_RS06985 2b6f69a909fc14d46426850aa24aab8e 570 SUPERFAMILY SSF52518 2 170 3.66E-53 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS06985 2b6f69a909fc14d46426850aa24aab8e 570 SUPERFAMILY SSF52467 150 353 5.78E-46 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS06985 2b6f69a909fc14d46426850aa24aab8e 570 Gene3D G3DSA:3.40.50.970 2 173 2.3E-64 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS06985 2b6f69a909fc14d46426850aa24aab8e 570 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 186 323 2.3E-36 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMD11_RS06985 2b6f69a909fc14d46426850aa24aab8e 570 SUPERFAMILY SSF52518 364 555 5.38E-47 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS06985 2b6f69a909fc14d46426850aa24aab8e 570 Gene3D G3DSA:3.40.50.1220 177 333 2.6E-47 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS26470 7c10f0343fe2d338608f5c826db60b82 223 Gene3D G3DSA:3.40.50.2300 3 125 3.4E-39 T 06-07-2017 SMD11_RS26470 7c10f0343fe2d338608f5c826db60b82 223 SMART SM00421 155 212 1.7E-28 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS26470 7c10f0343fe2d338608f5c826db60b82 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS26470 7c10f0343fe2d338608f5c826db60b82 223 Gene3D G3DSA:1.10.10.10 126 220 1.8E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26470 7c10f0343fe2d338608f5c826db60b82 223 Pfam PF00072 Response regulator receiver domain 5 119 1.9E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS26470 7c10f0343fe2d338608f5c826db60b82 223 SMART SM00448 3 118 1.4E-36 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS26470 7c10f0343fe2d338608f5c826db60b82 223 SUPERFAMILY SSF52172 3 129 1.41E-35 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS26470 7c10f0343fe2d338608f5c826db60b82 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 2.6E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS26470 7c10f0343fe2d338608f5c826db60b82 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 4.7E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS26470 7c10f0343fe2d338608f5c826db60b82 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 4.7E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS26470 7c10f0343fe2d338608f5c826db60b82 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 4.7E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS26470 7c10f0343fe2d338608f5c826db60b82 223 SUPERFAMILY SSF46894 148 218 2.93E-23 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS11835 00a849204a7f33e2ba5a46a87ad7ad0c 227 SUPERFAMILY SSF53335 26 226 5.47E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS11835 00a849204a7f33e2ba5a46a87ad7ad0c 227 Gene3D G3DSA:3.40.50.150 29 226 2.0E-49 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS11835 00a849204a7f33e2ba5a46a87ad7ad0c 227 Pfam PF01596 O-methyltransferase 51 224 2.1E-22 T 06-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 SMD11_RS26275 c4eac492e444a619f3c7a4c62ec5344e 502 Gene3D G3DSA:1.20.1250.20 23 203 3.6E-26 T 06-07-2017 SMD11_RS26275 c4eac492e444a619f3c7a4c62ec5344e 502 Gene3D G3DSA:1.20.1250.20 274 477 2.3E-16 T 06-07-2017 SMD11_RS26275 c4eac492e444a619f3c7a4c62ec5344e 502 SUPERFAMILY SSF103473 22 212 2.35E-52 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS26275 c4eac492e444a619f3c7a4c62ec5344e 502 SUPERFAMILY SSF103473 258 483 2.35E-52 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS26275 c4eac492e444a619f3c7a4c62ec5344e 502 Pfam PF07690 Major Facilitator Superfamily 26 424 5.3E-41 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS32790 f722ee05c0e531273b5c3778e4246ac3 172 SUPERFAMILY SSF52540 2 139 2.03E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS32790 f722ee05c0e531273b5c3778e4246ac3 172 Pfam PF07931 Chloramphenicol phosphotransferase-like protein 1 131 4.2E-46 T 06-07-2017 IPR012853 Chloramphenicol phosphotransferase-like GO:0005524|GO:0016740 SMD11_RS32790 f722ee05c0e531273b5c3778e4246ac3 172 Gene3D G3DSA:3.40.50.300 1 143 1.5E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21475 afc811acd9b11788f26c876728eb120b 373 Gene3D G3DSA:3.50.50.60 331 369 8.1E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS21475 afc811acd9b11788f26c876728eb120b 373 Gene3D G3DSA:3.50.50.60 1 78 8.1E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS21475 afc811acd9b11788f26c876728eb120b 373 Gene3D G3DSA:3.50.50.60 135 211 8.1E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS21475 afc811acd9b11788f26c876728eb120b 373 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 2 366 5.5E-100 T 06-07-2017 IPR017741 FAD-dependent oxidoreductase, HpnW SMD11_RS21475 afc811acd9b11788f26c876728eb120b 373 Pfam PF01266 FAD dependent oxidoreductase 3 369 4.0E-47 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD11_RS21475 afc811acd9b11788f26c876728eb120b 373 Gene3D G3DSA:3.30.9.10 82 134 6.5E-6 T 06-07-2017 SMD11_RS21475 afc811acd9b11788f26c876728eb120b 373 Gene3D G3DSA:3.30.9.10 212 256 6.5E-6 T 06-07-2017 SMD11_RS21475 afc811acd9b11788f26c876728eb120b 373 SUPERFAMILY SSF51905 331 371 5.18E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS21475 afc811acd9b11788f26c876728eb120b 373 SUPERFAMILY SSF51905 1 212 5.18E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05845 b95ec1986b0810370b3d4a4dcfe37720 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 189 0.0042 T 06-07-2017 SMD11_RS05845 b95ec1986b0810370b3d4a4dcfe37720 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 252 1.2E-65 T 06-07-2017 SMD11_RS05845 b95ec1986b0810370b3d4a4dcfe37720 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS05845 b95ec1986b0810370b3d4a4dcfe37720 253 SUPERFAMILY SSF51735 1 253 1.78E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05845 b95ec1986b0810370b3d4a4dcfe37720 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 9.9E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05845 b95ec1986b0810370b3d4a4dcfe37720 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 9.9E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05845 b95ec1986b0810370b3d4a4dcfe37720 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 9.9E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05845 b95ec1986b0810370b3d4a4dcfe37720 253 Gene3D G3DSA:3.40.50.720 1 252 8.8E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05845 b95ec1986b0810370b3d4a4dcfe37720 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05845 b95ec1986b0810370b3d4a4dcfe37720 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05845 b95ec1986b0810370b3d4a4dcfe37720 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05845 b95ec1986b0810370b3d4a4dcfe37720 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05845 b95ec1986b0810370b3d4a4dcfe37720 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05845 b95ec1986b0810370b3d4a4dcfe37720 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS12205 428f4e44a444bf92143678f15c9994fa 756 SUPERFAMILY SSF56601 288 655 9.39E-84 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS12205 428f4e44a444bf92143678f15c9994fa 756 SUPERFAMILY SSF56601 241 259 9.39E-84 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS12205 428f4e44a444bf92143678f15c9994fa 756 Pfam PF00912 Transglycosylase 78 255 4.1E-59 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 SMD11_RS12205 428f4e44a444bf92143678f15c9994fa 756 SUPERFAMILY SSF53955 70 271 1.63E-63 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS12205 428f4e44a444bf92143678f15c9994fa 756 Gene3D G3DSA:3.40.710.10 257 681 2.3E-100 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS12205 428f4e44a444bf92143678f15c9994fa 756 Gene3D G3DSA:1.10.3810.10 78 256 4.2E-65 T 06-07-2017 SMD11_RS12205 428f4e44a444bf92143678f15c9994fa 756 Pfam PF00905 Penicillin binding protein transpeptidase domain 360 603 2.3E-35 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD11_RS06380 8dc52b45340440f26ad0a90854f9dbbd 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06380 8dc52b45340440f26ad0a90854f9dbbd 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06380 8dc52b45340440f26ad0a90854f9dbbd 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 1.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06380 8dc52b45340440f26ad0a90854f9dbbd 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS06380 8dc52b45340440f26ad0a90854f9dbbd 267 SUPERFAMILY SSF51735 16 265 3.95E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06380 8dc52b45340440f26ad0a90854f9dbbd 267 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 23 40 8.6E-55 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS06380 8dc52b45340440f26ad0a90854f9dbbd 267 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 93 110 8.6E-55 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS06380 8dc52b45340440f26ad0a90854f9dbbd 267 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 243 262 8.6E-55 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS06380 8dc52b45340440f26ad0a90854f9dbbd 267 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 217 236 8.6E-55 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS06380 8dc52b45340440f26ad0a90854f9dbbd 267 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 178 201 8.6E-55 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS06380 8dc52b45340440f26ad0a90854f9dbbd 267 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 113 133 8.6E-55 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS06380 8dc52b45340440f26ad0a90854f9dbbd 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 264 2.8E-57 T 06-07-2017 SMD11_RS06380 8dc52b45340440f26ad0a90854f9dbbd 267 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 19 265 2.6E-107 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS06380 8dc52b45340440f26ad0a90854f9dbbd 267 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 17 196 0.0047 T 06-07-2017 SMD11_RS06380 8dc52b45340440f26ad0a90854f9dbbd 267 Gene3D G3DSA:3.40.50.720 11 265 1.1E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS28945 662ccc63b948ce523fd23a80bc79b0ea 378 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 104 170 3.8E-7 T 06-07-2017 IPR005065 Platelet-activating factor acetylhydrolase GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 SMD11_RS28945 662ccc63b948ce523fd23a80bc79b0ea 378 Gene3D G3DSA:3.40.50.1820 124 376 7.8E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28945 662ccc63b948ce523fd23a80bc79b0ea 378 Gene3D G3DSA:3.40.50.1820 41 87 7.8E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28945 662ccc63b948ce523fd23a80bc79b0ea 378 SUPERFAMILY SSF53474 113 309 4.85E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28945 662ccc63b948ce523fd23a80bc79b0ea 378 SUPERFAMILY SSF53474 344 366 4.85E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS07245 37c2d5ec3c594ea130e5f52f41f5c4ca 410 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 204 214 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site SMD11_RS07245 37c2d5ec3c594ea130e5f52f41f5c4ca 410 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 354 364 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site SMD11_RS07245 37c2d5ec3c594ea130e5f52f41f5c4ca 410 Gene3D G3DSA:3.30.70.80 46 133 8.3E-15 T 06-07-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 SMD11_RS07245 37c2d5ec3c594ea130e5f52f41f5c4ca 410 Gene3D G3DSA:3.40.50.200 138 407 3.8E-83 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS07245 37c2d5ec3c594ea130e5f52f41f5c4ca 410 Pfam PF00082 Subtilase family 162 392 2.5E-41 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS07245 37c2d5ec3c594ea130e5f52f41f5c4ca 410 Pfam PF05922 Peptidase inhibitor I9 54 127 8.8E-9 T 06-07-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 SMD11_RS07245 37c2d5ec3c594ea130e5f52f41f5c4ca 410 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 167 178 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site SMD11_RS07245 37c2d5ec3c594ea130e5f52f41f5c4ca 410 SUPERFAMILY SSF52743 138 398 8.64E-76 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS07245 37c2d5ec3c594ea130e5f52f41f5c4ca 410 SUPERFAMILY SSF54897 53 129 3.17E-7 T 06-07-2017 IPR009020 Proteinase propeptide inhibitor SMD11_RS07245 37c2d5ec3c594ea130e5f52f41f5c4ca 410 PRINTS PR00723 Subtilisin serine protease family (S8) signature 200 213 3.8E-20 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS07245 37c2d5ec3c594ea130e5f52f41f5c4ca 410 PRINTS PR00723 Subtilisin serine protease family (S8) signature 162 181 3.8E-20 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS07245 37c2d5ec3c594ea130e5f52f41f5c4ca 410 PRINTS PR00723 Subtilisin serine protease family (S8) signature 353 369 3.8E-20 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS30830 4621f46d8cf4b75bbea23a4a45ee9641 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 4.1E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS30830 4621f46d8cf4b75bbea23a4a45ee9641 288 SUPERFAMILY SSF53850 88 285 4.03E-24 T 06-07-2017 SMD11_RS30830 4621f46d8cf4b75bbea23a4a45ee9641 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.2E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS30830 4621f46d8cf4b75bbea23a4a45ee9641 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.2E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS30830 4621f46d8cf4b75bbea23a4a45ee9641 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.2E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS30830 4621f46d8cf4b75bbea23a4a45ee9641 288 Gene3D G3DSA:3.40.190.10 88 177 8.1E-12 T 06-07-2017 SMD11_RS30830 4621f46d8cf4b75bbea23a4a45ee9641 288 SUPERFAMILY SSF46785 2 81 3.18E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30830 4621f46d8cf4b75bbea23a4a45ee9641 288 Gene3D G3DSA:1.10.10.10 2 81 6.8E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30830 4621f46d8cf4b75bbea23a4a45ee9641 288 Pfam PF03466 LysR substrate binding domain 88 283 1.8E-23 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS30830 4621f46d8cf4b75bbea23a4a45ee9641 288 Gene3D G3DSA:3.40.190.10 178 256 6.7E-11 T 06-07-2017 SMD11_RS11955 a2139949624a4db9522b9268768724ce 706 Gene3D G3DSA:3.40.50.1820 456 703 9.1E-76 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS11955 a2139949624a4db9522b9268768724ce 706 Gene3D G3DSA:2.140.10.30 17 425 3.8E-67 T 06-07-2017 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 SMD11_RS11955 a2139949624a4db9522b9268768724ce 706 SUPERFAMILY SSF82171 20 338 7.19E-31 T 06-07-2017 SMD11_RS11955 a2139949624a4db9522b9268768724ce 706 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 543 573 - T 06-07-2017 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 SMD11_RS11955 a2139949624a4db9522b9268768724ce 706 Pfam PF07676 WD40-like Beta Propeller Repeat 24 51 0.092 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS11955 a2139949624a4db9522b9268768724ce 706 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 112 337 6.5E-31 T 06-07-2017 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 SMD11_RS11955 a2139949624a4db9522b9268768724ce 706 SUPERFAMILY SSF53474 459 704 3.75E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS11955 a2139949624a4db9522b9268768724ce 706 Pfam PF00326 Prolyl oligopeptidase family 502 705 8.7E-47 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMD11_RS23370 79988c8cb4e8e1cba1e157df12d2d320 212 Pfam PF09335 SNARE associated Golgi protein 64 170 3.6E-9 T 06-07-2017 IPR032816 SNARE associated Golgi protein SMD11_RS21410 a7f1c94fd67f752433b50487d9180bdf 75 Pfam PF04149 Domain of unknown function (DUF397) 10 63 2.0E-17 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS29295 5245e2e8207b61128e1e46c1939896f4 360 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 3 291 5.2E-84 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMD11_RS29295 5245e2e8207b61128e1e46c1939896f4 360 SUPERFAMILY SSF55931 1 349 6.18E-87 T 06-07-2017 SMD11_RS29295 5245e2e8207b61128e1e46c1939896f4 360 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 4 286 1.5E-52 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMD11_RS29295 5245e2e8207b61128e1e46c1939896f4 360 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 360 73.845 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMD11_RS10415 0d830b6f758d7529486da04d39643a2d 527 Gene3D G3DSA:3.40.50.200 99 414 1.6E-29 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS10415 0d830b6f758d7529486da04d39643a2d 527 Gene3D G3DSA:3.40.50.200 19 41 1.6E-29 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS10415 0d830b6f758d7529486da04d39643a2d 527 PRINTS PR00723 Subtilisin serine protease family (S8) signature 369 385 2.1E-6 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS10415 0d830b6f758d7529486da04d39643a2d 527 PRINTS PR00723 Subtilisin serine protease family (S8) signature 166 179 2.1E-6 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS10415 0d830b6f758d7529486da04d39643a2d 527 PRINTS PR00723 Subtilisin serine protease family (S8) signature 130 149 2.1E-6 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS10415 0d830b6f758d7529486da04d39643a2d 527 SUPERFAMILY SSF52743 98 426 3.53E-30 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS10415 0d830b6f758d7529486da04d39643a2d 527 Pfam PF00082 Subtilase family 166 410 1.5E-9 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS10415 0d830b6f758d7529486da04d39643a2d 527 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 370 380 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site SMD11_RS13380 e01991e2097ac30028dfc23d48c2b8a4 518 Pfam PF00069 Protein kinase domain 17 267 2.2E-40 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS13380 e01991e2097ac30028dfc23d48c2b8a4 518 SMART SM00220 15 275 1.2E-58 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS13380 e01991e2097ac30028dfc23d48c2b8a4 518 Gene3D G3DSA:1.10.510.10 87 269 5.1E-44 T 06-07-2017 SMD11_RS13380 e01991e2097ac30028dfc23d48c2b8a4 518 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 139 151 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS13380 e01991e2097ac30028dfc23d48c2b8a4 518 SUPERFAMILY SSF56112 10 293 4.39E-64 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS13380 e01991e2097ac30028dfc23d48c2b8a4 518 Gene3D G3DSA:3.30.200.20 8 86 2.3E-20 T 06-07-2017 SMD11_RS12460 2f7a80a7259a5f87dc280191abf523bf 348 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS12460 2f7a80a7259a5f87dc280191abf523bf 348 SMART SM00382 29 211 2.0E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS12460 2f7a80a7259a5f87dc280191abf523bf 348 Pfam PF13732 Domain of unknown function (DUF4162) 217 307 5.9E-9 T 06-07-2017 IPR025302 Domain of unknown function DUF4162 SMD11_RS12460 2f7a80a7259a5f87dc280191abf523bf 348 Gene3D G3DSA:3.40.50.300 3 236 1.1E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12460 2f7a80a7259a5f87dc280191abf523bf 348 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 309 2.8E-109 T 06-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMD11_RS12460 2f7a80a7259a5f87dc280191abf523bf 348 Pfam PF00005 ABC transporter 20 163 1.4E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS12460 2f7a80a7259a5f87dc280191abf523bf 348 SUPERFAMILY SSF52540 7 227 3.13E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13815 cf6ec6735035a359237fcfe081d6543b 127 SMART SM00357 3 65 2.5E-21 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 SMD11_RS13815 cf6ec6735035a359237fcfe081d6543b 127 PRINTS PR00050 Cold shock protein signature 38 56 7.8E-14 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS13815 cf6ec6735035a359237fcfe081d6543b 127 PRINTS PR00050 Cold shock protein signature 24 33 7.8E-14 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS13815 cf6ec6735035a359237fcfe081d6543b 127 PRINTS PR00050 Cold shock protein signature 4 19 7.8E-14 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS13815 cf6ec6735035a359237fcfe081d6543b 127 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 7.1E-21 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS13815 cf6ec6735035a359237fcfe081d6543b 127 Gene3D G3DSA:2.40.50.140 3 64 2.4E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS13815 cf6ec6735035a359237fcfe081d6543b 127 SUPERFAMILY SSF50249 2 65 9.64E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS13815 cf6ec6735035a359237fcfe081d6543b 127 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 06-07-2017 IPR019844 Cold-shock conserved site SMD11_RS13020 e8a1a4579c8160492bfe464d18cf360e 430 Pfam PF07730 Histidine kinase 234 299 2.7E-14 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS13020 e8a1a4579c8160492bfe464d18cf360e 430 Gene3D G3DSA:3.30.565.10 336 420 4.2E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS13020 e8a1a4579c8160492bfe464d18cf360e 430 Pfam PF13796 Putative sensor 31 203 4.7E-19 T 06-07-2017 IPR025828 Putative sensor domain SMD11_RS13020 e8a1a4579c8160492bfe464d18cf360e 430 SUPERFAMILY SSF55874 317 420 2.1E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS18500 841d4455f8111bbe3b9b6931c0981283 398 Gene3D G3DSA:3.20.20.70 18 351 4.0E-63 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS18500 841d4455f8111bbe3b9b6931c0981283 398 Pfam PF04055 Radical SAM superfamily 65 237 1.8E-16 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS18500 841d4455f8111bbe3b9b6931c0981283 398 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 19 359 8.7E-140 T 06-07-2017 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMD11_RS18500 841d4455f8111bbe3b9b6931c0981283 398 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 17 362 50.61 T 06-07-2017 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMD11_RS18500 841d4455f8111bbe3b9b6931c0981283 398 PIRSF PIRSF004762 1 371 4.6E-107 T 06-07-2017 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD11_RS18500 841d4455f8111bbe3b9b6931c0981283 398 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 57 359 9.1E-103 T 06-07-2017 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 SMD11_RS18500 841d4455f8111bbe3b9b6931c0981283 398 SMART SM00729 54 280 0.0067 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD11_RS18500 841d4455f8111bbe3b9b6931c0981283 398 SUPERFAMILY SSF102114 17 351 3.53E-51 T 06-07-2017 SMD11_RS32745 b6954ea8f4dfc674dfa99e038d6f87e7 144 Gene3D G3DSA:3.10.180.10 14 126 2.1E-36 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS32745 b6954ea8f4dfc674dfa99e038d6f87e7 144 SUPERFAMILY SSF54593 11 136 2.4E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS11735 0e1b0c945d44483e993c974213477ae4 266 Gene3D G3DSA:3.10.180.10 14 124 3.7E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS11735 0e1b0c945d44483e993c974213477ae4 266 Gene3D G3DSA:3.10.180.10 139 262 3.2E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS11735 0e1b0c945d44483e993c974213477ae4 266 SUPERFAMILY SSF54593 140 262 2.82E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS11735 0e1b0c945d44483e993c974213477ae4 266 SUPERFAMILY SSF54593 14 128 7.25E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS24835 e9114ffa1317d9eec1fb9ec90037b4f5 224 Gene3D G3DSA:1.10.10.10 128 220 2.1E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS24835 e9114ffa1317d9eec1fb9ec90037b4f5 224 SMART SM00421 157 214 3.5E-25 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24835 e9114ffa1317d9eec1fb9ec90037b4f5 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 6.4E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24835 e9114ffa1317d9eec1fb9ec90037b4f5 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 6.4E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24835 e9114ffa1317d9eec1fb9ec90037b4f5 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 6.4E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24835 e9114ffa1317d9eec1fb9ec90037b4f5 224 Pfam PF00072 Response regulator receiver domain 5 123 2.9E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS24835 e9114ffa1317d9eec1fb9ec90037b4f5 224 Gene3D G3DSA:3.40.50.2300 2 127 1.4E-33 T 06-07-2017 SMD11_RS24835 e9114ffa1317d9eec1fb9ec90037b4f5 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 214 2.5E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24835 e9114ffa1317d9eec1fb9ec90037b4f5 224 SUPERFAMILY SSF46894 153 219 5.78E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS24835 e9114ffa1317d9eec1fb9ec90037b4f5 224 SMART SM00448 3 123 7.7E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS24835 e9114ffa1317d9eec1fb9ec90037b4f5 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24835 e9114ffa1317d9eec1fb9ec90037b4f5 224 SUPERFAMILY SSF52172 3 135 2.42E-29 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS17295 551fabc8fbbd777f12b2db1383f8dcba 428 SUPERFAMILY SSF53187 10 91 1.37E-92 T 06-07-2017 SMD11_RS17295 551fabc8fbbd777f12b2db1383f8dcba 428 SUPERFAMILY SSF53187 210 427 1.37E-92 T 06-07-2017 SMD11_RS17295 551fabc8fbbd777f12b2db1383f8dcba 428 Hamap MF_00467 Probable M18 family aminopeptidase 2 [apeB]. 1 428 55.776 T 06-07-2017 IPR022984 M18 family aminopeptidase 2, putative GO:0004177 SMD11_RS17295 551fabc8fbbd777f12b2db1383f8dcba 428 Gene3D G3DSA:2.30.250.10 91 216 6.1E-40 T 06-07-2017 IPR023358 Peptidase M18, domain 2 GO:0004177 SMD11_RS17295 551fabc8fbbd777f12b2db1383f8dcba 428 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 18 425 9.0E-127 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMD11_RS17295 551fabc8fbbd777f12b2db1383f8dcba 428 Gene3D G3DSA:3.40.630.10 219 427 8.2E-103 T 06-07-2017 SMD11_RS17295 551fabc8fbbd777f12b2db1383f8dcba 428 Gene3D G3DSA:3.40.630.10 11 90 8.2E-103 T 06-07-2017 SMD11_RS17295 551fabc8fbbd777f12b2db1383f8dcba 428 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 304 320 5.5E-37 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMD11_RS17295 551fabc8fbbd777f12b2db1383f8dcba 428 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 113 133 5.5E-37 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMD11_RS17295 551fabc8fbbd777f12b2db1383f8dcba 428 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 80 96 5.5E-37 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMD11_RS17295 551fabc8fbbd777f12b2db1383f8dcba 428 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 393 408 5.5E-37 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMD11_RS17295 551fabc8fbbd777f12b2db1383f8dcba 428 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 261 279 5.5E-37 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 SMD11_RS17295 551fabc8fbbd777f12b2db1383f8dcba 428 SUPERFAMILY SSF101821 92 210 8.06E-34 T 06-07-2017 SMD11_RS12365 22c155a72f136ebeb6e0d4ca78c2a816 436 SMART SM00631 114 406 2.8E-95 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS12365 22c155a72f136ebeb6e0d4ca78c2a816 436 SUPERFAMILY SSF53187 112 417 9.08E-82 T 06-07-2017 SMD11_RS12365 22c155a72f136ebeb6e0d4ca78c2a816 436 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 165 187 - T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS12365 22c155a72f136ebeb6e0d4ca78c2a816 436 Gene3D G3DSA:3.40.630.10 110 419 1.2E-95 T 06-07-2017 SMD11_RS12365 22c155a72f136ebeb6e0d4ca78c2a816 436 Pfam PF00246 Zinc carboxypeptidase 128 409 6.2E-70 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS12365 22c155a72f136ebeb6e0d4ca78c2a816 436 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 306 319 7.7E-13 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS12365 22c155a72f136ebeb6e0d4ca78c2a816 436 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 140 152 7.7E-13 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS12365 22c155a72f136ebeb6e0d4ca78c2a816 436 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 165 179 7.7E-13 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS12365 22c155a72f136ebeb6e0d4ca78c2a816 436 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 247 255 7.7E-13 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS12365 22c155a72f136ebeb6e0d4ca78c2a816 436 ProSitePatterns PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 309 319 - T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS18960 e512b21f203d097ac1d3f6df811e2b82 132 SUPERFAMILY SSF56047 3 132 3.92E-44 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18960 e512b21f203d097ac1d3f6df811e2b82 132 Pfam PF00410 Ribosomal protein S8 5 132 9.3E-50 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18960 e512b21f203d097ac1d3f6df811e2b82 132 Gene3D G3DSA:3.30.1370.30 2 72 5.1E-28 T 06-07-2017 SMD11_RS18960 e512b21f203d097ac1d3f6df811e2b82 132 Gene3D G3DSA:3.30.1490.10 76 132 6.2E-28 T 06-07-2017 SMD11_RS18960 e512b21f203d097ac1d3f6df811e2b82 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.623 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS14965 e41b6baefd946db52b392b2c53537cd5 340 Gene3D G3DSA:3.40.50.620 41 203 4.4E-13 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS14965 e41b6baefd946db52b392b2c53537cd5 340 Pfam PF01171 PP-loop family 41 219 4.8E-38 T 06-07-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 SMD11_RS14965 e41b6baefd946db52b392b2c53537cd5 340 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 18 329 20.395 T 06-07-2017 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SMD11_RS14965 e41b6baefd946db52b392b2c53537cd5 340 Pfam PF09179 TilS substrate binding domain 269 335 2.1E-10 T 06-07-2017 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SMD11_RS14965 e41b6baefd946db52b392b2c53537cd5 340 SUPERFAMILY SSF82829 231 335 8.89E-16 T 06-07-2017 SMD11_RS14965 e41b6baefd946db52b392b2c53537cd5 340 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 41 222 5.7E-44 T 06-07-2017 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SMD11_RS14965 e41b6baefd946db52b392b2c53537cd5 340 SUPERFAMILY SSF52402 41 251 2.71E-47 T 06-07-2017 SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 SUPERFAMILY SSF46689 137 186 4.26E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 137 179 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 Gene3D G3DSA:1.10.10.60 139 185 9.3E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 SUPERFAMILY SSF48150 304 480 6.44E-35 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 SMART SM00478 324 482 2.2E-20 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 Gene3D G3DSA:1.10.340.30 317 432 1.0E-27 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 SMART SM01009 199 314 2.2E-44 T 06-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 SMART SM00342 100 183 2.2E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 Pfam PF12833 Helix-turn-helix domain 106 185 1.7E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 Gene3D G3DSA:3.40.10.10 1 82 5.2E-34 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 Pfam PF06029 AlkA N-terminal domain 199 314 9.8E-29 T 06-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 SUPERFAMILY SSF55945 199 294 1.33E-23 T 06-07-2017 SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 Pfam PF02805 Metal binding domain of Ada 8 71 1.7E-27 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 SUPERFAMILY SSF57884 1 83 1.96E-31 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 Gene3D G3DSA:3.30.310.20 199 314 4.9E-33 T 06-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 Gene3D G3DSA:1.10.1670.10 433 486 6.5E-18 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SMD11_RS06565 b7ec84bdb0ef185b311c91cb42bff269 491 Gene3D G3DSA:1.10.10.60 83 138 2.5E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS17785 4fa9894bb7fa656bb7975f8752638a22 428 Gene3D G3DSA:3.90.170.10 266 422 7.6E-68 T 06-07-2017 SMD11_RS17785 4fa9894bb7fa656bb7975f8752638a22 428 Gene3D G3DSA:3.40.440.10 195 264 2.3E-71 T 06-07-2017 SMD11_RS17785 4fa9894bb7fa656bb7975f8752638a22 428 Gene3D G3DSA:3.40.440.10 4 93 2.3E-71 T 06-07-2017 SMD11_RS17785 4fa9894bb7fa656bb7975f8752638a22 428 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 06-07-2017 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMD11_RS17785 4fa9894bb7fa656bb7975f8752638a22 428 SUPERFAMILY SSF52540 3 425 4.36E-174 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17785 4fa9894bb7fa656bb7975f8752638a22 428 Pfam PF00709 Adenylosuccinate synthetase 5 421 1.9E-178 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMD11_RS17785 4fa9894bb7fa656bb7975f8752638a22 428 Gene3D G3DSA:1.10.300.10 101 194 4.5E-35 T 06-07-2017 SMD11_RS17785 4fa9894bb7fa656bb7975f8752638a22 428 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 428 200.785 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMD11_RS17785 4fa9894bb7fa656bb7975f8752638a22 428 SMART SM00788 3 422 6.2E-287 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMD11_RS17785 4fa9894bb7fa656bb7975f8752638a22 428 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 423 9.9E-169 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMD11_RS17785 4fa9894bb7fa656bb7975f8752638a22 428 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 06-07-2017 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SMD11_RS24070 978ebe4a8b4a33be104fc81d358cc315 207 Gene3D G3DSA:1.10.10.10 8 73 5.2E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS24070 978ebe4a8b4a33be104fc81d358cc315 207 SMART SM00345 13 71 1.5E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS24070 978ebe4a8b4a33be104fc81d358cc315 207 SMART SM00895 81 202 1.7E-8 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS24070 978ebe4a8b4a33be104fc81d358cc315 207 SUPERFAMILY SSF48008 78 191 4.45E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS24070 978ebe4a8b4a33be104fc81d358cc315 207 Pfam PF07729 FCD domain 82 191 1.1E-15 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS24070 978ebe4a8b4a33be104fc81d358cc315 207 Gene3D G3DSA:1.20.120.530 75 191 1.5E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS24070 978ebe4a8b4a33be104fc81d358cc315 207 SUPERFAMILY SSF46785 8 97 4.17E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS24070 978ebe4a8b4a33be104fc81d358cc315 207 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 2.0E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS24685 c58f0aed2c3dfb3a2bfa489223719a96 197 Gene3D G3DSA:3.30.230.40 3 89 9.9E-37 T 06-07-2017 SMD11_RS24685 c58f0aed2c3dfb3a2bfa489223719a96 197 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 06-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SMD11_RS24685 c58f0aed2c3dfb3a2bfa489223719a96 197 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 176 5.3E-62 T 06-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SMD11_RS24685 c58f0aed2c3dfb3a2bfa489223719a96 197 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 06-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SMD11_RS24685 c58f0aed2c3dfb3a2bfa489223719a96 197 Gene3D G3DSA:3.30.230.40 91 197 2.9E-29 T 06-07-2017 SMD11_RS24685 c58f0aed2c3dfb3a2bfa489223719a96 197 SUPERFAMILY SSF54211 88 181 1.64E-30 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS24685 c58f0aed2c3dfb3a2bfa489223719a96 197 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 197 40.9 T 06-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SMD11_RS24685 c58f0aed2c3dfb3a2bfa489223719a96 197 SUPERFAMILY SSF54211 3 86 5.18E-33 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS17740 e8395c37334b0644470306219fac3adf 340 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 337 1.1E-129 T 06-07-2017 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 SMD11_RS17740 e8395c37334b0644470306219fac3adf 340 PIRSF PIRSF001359 5 338 6.4E-63 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMD11_RS17740 e8395c37334b0644470306219fac3adf 340 SUPERFAMILY SSF51569 4 336 5.57E-94 T 06-07-2017 SMD11_RS17740 e8395c37334b0644470306219fac3adf 340 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMD11_RS17740 e8395c37334b0644470306219fac3adf 340 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 336 1.5E-77 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMD11_RS17740 e8395c37334b0644470306219fac3adf 340 Gene3D G3DSA:3.20.20.70 2 337 3.9E-114 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS17740 e8395c37334b0644470306219fac3adf 340 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 9 336 1.1E-70 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMD11_RS00880 8e9ee72ea8069290cba6d01b501c8e52 263 Pfam PF00293 NUDIX domain 120 229 1.9E-14 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS00880 8e9ee72ea8069290cba6d01b501c8e52 263 SUPERFAMILY SSF55811 113 234 7.58E-21 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS00880 8e9ee72ea8069290cba6d01b501c8e52 263 Gene3D G3DSA:3.90.79.10 117 238 7.3E-21 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS00880 8e9ee72ea8069290cba6d01b501c8e52 263 ProSitePatterns PS00893 Nudix box signature. 144 165 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD11_RS19705 1d0d7bb931f89ceed0c77c871c8dac8f 511 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 27 441 7.4E-71 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS19705 1d0d7bb931f89ceed0c77c871c8dac8f 511 Gene3D G3DSA:1.20.1250.20 21 211 2.7E-29 T 06-07-2017 SMD11_RS19705 1d0d7bb931f89ceed0c77c871c8dac8f 511 Gene3D G3DSA:1.20.1250.20 290 487 9.0E-13 T 06-07-2017 SMD11_RS19705 1d0d7bb931f89ceed0c77c871c8dac8f 511 Pfam PF07690 Major Facilitator Superfamily 32 433 4.1E-50 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS19705 1d0d7bb931f89ceed0c77c871c8dac8f 511 SUPERFAMILY SSF103473 268 490 3.27E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS19705 1d0d7bb931f89ceed0c77c871c8dac8f 511 SUPERFAMILY SSF103473 7 217 3.27E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS19705 1d0d7bb931f89ceed0c77c871c8dac8f 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 151 175 4.9E-6 T 06-07-2017 SMD11_RS19705 1d0d7bb931f89ceed0c77c871c8dac8f 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 121 141 4.9E-6 T 06-07-2017 SMD11_RS19705 1d0d7bb931f89ceed0c77c871c8dac8f 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 30 54 4.9E-6 T 06-07-2017 SMD11_RS02770 29bc0d617c874f53f0a9bac9b007154d 194 Gene3D G3DSA:1.10.10.10 1 53 2.2E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02770 29bc0d617c874f53f0a9bac9b007154d 194 SUPERFAMILY SSF46785 2 52 2.72E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02770 29bc0d617c874f53f0a9bac9b007154d 194 Pfam PF08279 HTH domain 1 49 2.4E-15 T 06-07-2017 IPR013196 Helix-turn-helix, type 11 SMD11_RS14120 a2bddb9e58a89745dcd6f9cf6ed47d52 316 Gene3D G3DSA:3.40.1280.10 163 315 2.2E-48 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMD11_RS14120 a2bddb9e58a89745dcd6f9cf6ed47d52 316 SUPERFAMILY SSF75217 139 315 2.16E-42 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases SMD11_RS14120 a2bddb9e58a89745dcd6f9cf6ed47d52 316 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 74 315 1.0E-59 T 06-07-2017 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 SMD11_RS14120 a2bddb9e58a89745dcd6f9cf6ed47d52 316 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 75 151 2.1E-18 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 SMD11_RS14120 a2bddb9e58a89745dcd6f9cf6ed47d52 316 SUPERFAMILY SSF55315 71 148 2.94E-16 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like SMD11_RS14120 a2bddb9e58a89745dcd6f9cf6ed47d52 316 Gene3D G3DSA:3.30.1330.30 72 147 7.8E-20 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like SMD11_RS14120 a2bddb9e58a89745dcd6f9cf6ed47d52 316 Pfam PF00588 SpoU rRNA Methylase family 168 309 1.1E-32 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SMD11_RS14120 a2bddb9e58a89745dcd6f9cf6ed47d52 316 SMART SM00967 75 151 5.3E-17 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 SMD11_RS10400 0fa5170ce0488bce62c6345a3fa1dcaa 730 Gene3D G3DSA:2.60.40.1180 626 729 3.5E-34 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta SMD11_RS10400 0fa5170ce0488bce62c6345a3fa1dcaa 730 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 106 728 5.8E-296 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 SMD11_RS10400 0fa5170ce0488bce62c6345a3fa1dcaa 730 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 98 730 43.163 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 SMD11_RS10400 0fa5170ce0488bce62c6345a3fa1dcaa 730 Gene3D G3DSA:2.60.40.10 112 218 2.6E-36 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS10400 0fa5170ce0488bce62c6345a3fa1dcaa 730 Gene3D G3DSA:2.60.40.10 15 103 1.6E-15 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS10400 0fa5170ce0488bce62c6345a3fa1dcaa 730 SUPERFAMILY SSF51445 168 620 1.3E-111 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS10400 0fa5170ce0488bce62c6345a3fa1dcaa 730 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 631 729 3.7E-20 T 06-07-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 SMD11_RS10400 0fa5170ce0488bce62c6345a3fa1dcaa 730 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 122 204 2.1E-21 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 SMD11_RS10400 0fa5170ce0488bce62c6345a3fa1dcaa 730 SUPERFAMILY SSF51011 626 729 8.43E-31 T 06-07-2017 SMD11_RS10400 0fa5170ce0488bce62c6345a3fa1dcaa 730 SMART SM00642 247 607 9.8E-8 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS10400 0fa5170ce0488bce62c6345a3fa1dcaa 730 PIRSF PIRSF000463 9 730 1.4E-292 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 SMD11_RS10400 0fa5170ce0488bce62c6345a3fa1dcaa 730 SUPERFAMILY SSF81296 17 110 9.33E-19 T 06-07-2017 IPR014756 Immunoglobulin E-set SMD11_RS10400 0fa5170ce0488bce62c6345a3fa1dcaa 730 Pfam PF00128 Alpha amylase, catalytic domain 263 335 3.3E-10 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS10400 0fa5170ce0488bce62c6345a3fa1dcaa 730 Gene3D G3DSA:3.20.20.80 242 614 2.2E-88 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS06755 296f668231523dc5316a2f7c55fbc5e5 259 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 258 1.1E-79 T 06-07-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 SMD11_RS06755 296f668231523dc5316a2f7c55fbc5e5 259 Gene3D G3DSA:3.60.10.10 1 258 2.1E-75 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS06755 296f668231523dc5316a2f7c55fbc5e5 259 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 256 5.5E-59 T 06-07-2017 SMD11_RS06755 296f668231523dc5316a2f7c55fbc5e5 259 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 250 2.7E-20 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS06755 296f668231523dc5316a2f7c55fbc5e5 259 SUPERFAMILY SSF56219 1 258 3.53E-67 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS10135 70c77a2b3939aadd0b3538989a89c2f8 98 SUPERFAMILY SSF141000 4 94 1.31E-27 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SMD11_RS10135 70c77a2b3939aadd0b3538989a89c2f8 98 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 9.1E-17 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SMD11_RS10135 70c77a2b3939aadd0b3538989a89c2f8 98 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 1.8E-24 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SMD11_RS10135 70c77a2b3939aadd0b3538989a89c2f8 98 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 24.015 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SMD11_RS11020 d7f7e382d27d55521e21cbd47ca64f32 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 153 1.3E-20 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD11_RS11020 d7f7e382d27d55521e21cbd47ca64f32 288 SUPERFAMILY SSF51735 1 154 3.01E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS11020 d7f7e382d27d55521e21cbd47ca64f32 288 Gene3D G3DSA:3.40.50.720 1 158 1.4E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS11020 d7f7e382d27d55521e21cbd47ca64f32 288 Gene3D G3DSA:1.10.1040.10 202 284 3.3E-5 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS11020 d7f7e382d27d55521e21cbd47ca64f32 288 PIRSF PIRSF000103 1 288 2.4E-39 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD11_RS12410 1fde5327e3c98183fa6303a930a4fa05 609 Gene3D G3DSA:3.90.228.20 249 318 2.5E-33 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SMD11_RS12410 1fde5327e3c98183fa6303a930a4fa05 609 Gene3D G3DSA:3.90.228.20 330 608 1.3E-103 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SMD11_RS12410 1fde5327e3c98183fa6303a930a4fa05 609 SUPERFAMILY SSF68923 10 248 5.75E-96 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SMD11_RS12410 1fde5327e3c98183fa6303a930a4fa05 609 SUPERFAMILY SSF53795 249 608 6.64E-161 T 06-07-2017 SMD11_RS12410 1fde5327e3c98183fa6303a930a4fa05 609 Gene3D G3DSA:3.40.449.10 11 248 2.2E-98 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SMD11_RS12410 1fde5327e3c98183fa6303a930a4fa05 609 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 273 281 - T 06-07-2017 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMD11_RS12410 1fde5327e3c98183fa6303a930a4fa05 609 PIRSF PIRSF001348 2 609 3.2E-280 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMD11_RS12410 1fde5327e3c98183fa6303a930a4fa05 609 Pfam PF00821 Phosphoenolpyruvate carboxykinase 19 608 2.1E-283 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMD11_RS12410 1fde5327e3c98183fa6303a930a4fa05 609 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 8 609 52.56 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 SMD11_RS27835 bfbfcf26f8956f0c3a7b761ed79bfd09 400 Pfam PF00704 Glycosyl hydrolases family 18 36 389 1.6E-73 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 SMD11_RS27835 bfbfcf26f8956f0c3a7b761ed79bfd09 400 Gene3D G3DSA:3.10.50.10 303 361 1.7E-20 T 06-07-2017 IPR029070 Chitinase insertion domain SMD11_RS27835 bfbfcf26f8956f0c3a7b761ed79bfd09 400 SUPERFAMILY SSF51445 359 395 2.66E-84 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS27835 bfbfcf26f8956f0c3a7b761ed79bfd09 400 SUPERFAMILY SSF51445 31 299 2.66E-84 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS27835 bfbfcf26f8956f0c3a7b761ed79bfd09 400 SMART SM00636 35 389 6.3E-111 T 06-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 SMD11_RS27835 bfbfcf26f8956f0c3a7b761ed79bfd09 400 Gene3D G3DSA:3.20.20.80 26 302 1.5E-86 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS27835 bfbfcf26f8956f0c3a7b761ed79bfd09 400 Gene3D G3DSA:3.20.20.80 366 399 1.5E-86 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS27835 bfbfcf26f8956f0c3a7b761ed79bfd09 400 SUPERFAMILY SSF54556 301 360 2.9E-12 T 06-07-2017 IPR029070 Chitinase insertion domain SMD11_RS27835 bfbfcf26f8956f0c3a7b761ed79bfd09 400 ProSitePatterns PS01095 Chitinases family 18 active site. 170 178 - T 06-07-2017 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 SMD11_RS33440 77a305bd51b74c76e2e156a8f6c361fc 263 SUPERFAMILY SSF46894 195 258 2.04E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS33440 77a305bd51b74c76e2e156a8f6c361fc 263 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 213 229 2.3E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS33440 77a305bd51b74c76e2e156a8f6c361fc 263 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 199 213 2.3E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS33440 77a305bd51b74c76e2e156a8f6c361fc 263 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 229 241 2.3E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS33440 77a305bd51b74c76e2e156a8f6c361fc 263 SUPERFAMILY SSF55781 32 170 1.77E-7 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS33440 77a305bd51b74c76e2e156a8f6c361fc 263 Pfam PF03472 Autoinducer binding domain 35 165 1.5E-5 T 06-07-2017 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain SMD11_RS33440 77a305bd51b74c76e2e156a8f6c361fc 263 Gene3D G3DSA:1.10.10.10 198 257 5.6E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33440 77a305bd51b74c76e2e156a8f6c361fc 263 ProSitePatterns PS00622 LuxR-type HTH domain signature. 213 240 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS33440 77a305bd51b74c76e2e156a8f6c361fc 263 Gene3D G3DSA:3.30.450.80 27 197 8.1E-8 T 06-07-2017 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain SMD11_RS33440 77a305bd51b74c76e2e156a8f6c361fc 263 Pfam PF00196 Bacterial regulatory proteins, luxR family 199 250 4.4E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS33440 77a305bd51b74c76e2e156a8f6c361fc 263 SMART SM00421 196 253 1.0E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS26715 bc52f91920c516011973e5641cc2020a 128 Pfam PF00453 Ribosomal protein L20 3 109 2.9E-44 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS26715 bc52f91920c516011973e5641cc2020a 128 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS26715 bc52f91920c516011973e5641cc2020a 128 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 113 1.7E-44 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS26715 bc52f91920c516011973e5641cc2020a 128 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 3.0E-24 T 06-07-2017 SMD11_RS26715 bc52f91920c516011973e5641cc2020a 128 Gene3D G3DSA:1.10.1900.20 56 117 7.6E-32 T 06-07-2017 SMD11_RS26715 bc52f91920c516011973e5641cc2020a 128 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.0E-37 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS26715 bc52f91920c516011973e5641cc2020a 128 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.0E-37 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS26715 bc52f91920c516011973e5641cc2020a 128 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.0E-37 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS26715 bc52f91920c516011973e5641cc2020a 128 SUPERFAMILY SSF74731 3 117 1.96E-45 T 06-07-2017 SMD11_RS26715 bc52f91920c516011973e5641cc2020a 128 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.635 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09995 5d9a8771b6b7c08f4626a4e8bd3b0d8d 543 Gene3D G3DSA:3.40.309.10 304 501 5.2E-41 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS09995 5d9a8771b6b7c08f4626a4e8bd3b0d8d 543 Gene3D G3DSA:3.40.605.10 41 303 5.5E-64 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS09995 5d9a8771b6b7c08f4626a4e8bd3b0d8d 543 SUPERFAMILY SSF53720 8 528 2.62E-122 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS09995 5d9a8771b6b7c08f4626a4e8bd3b0d8d 543 Pfam PF00171 Aldehyde dehydrogenase family 56 526 4.7E-101 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS09995 5d9a8771b6b7c08f4626a4e8bd3b0d8d 543 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 12 542 7.8E-241 T 06-07-2017 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0006537|GO:0006561 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-70688 SMD11_RS09995 5d9a8771b6b7c08f4626a4e8bd3b0d8d 543 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 321 332 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS06420 6eea9945388af5cd83037b2ad3018ec9 340 SUPERFAMILY SSF51735 6 261 9.33E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06420 6eea9945388af5cd83037b2ad3018ec9 340 Gene3D G3DSA:3.40.50.720 3 226 1.2E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06420 6eea9945388af5cd83037b2ad3018ec9 340 Pfam PF07993 Male sterility protein 41 208 8.4E-31 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 SMD11_RS10010 5d2c14d428d6bbe84d870cdb64ea5c5f 599 Gene3D G3DSA:1.20.140.10 456 584 3.9E-16 T 06-07-2017 SMD11_RS10010 5d2c14d428d6bbe84d870cdb64ea5c5f 599 Gene3D G3DSA:1.20.140.10 287 434 1.2E-31 T 06-07-2017 SMD11_RS10010 5d2c14d428d6bbe84d870cdb64ea5c5f 599 PIRSF PIRSF000168 9 597 3.3E-101 T 06-07-2017 IPR012258 Acyl-CoA oxidase GO:0003997|GO:0005777|GO:0006631|GO:0050660|GO:0055114 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS10010 5d2c14d428d6bbe84d870cdb64ea5c5f 599 SUPERFAMILY SSF47203 452 592 1.38E-19 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS10010 5d2c14d428d6bbe84d870cdb64ea5c5f 599 SUPERFAMILY SSF56645 50 257 1.07E-24 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS10010 5d2c14d428d6bbe84d870cdb64ea5c5f 599 Gene3D G3DSA:2.40.110.10 136 263 6.2E-25 T 06-07-2017 SMD11_RS10010 5d2c14d428d6bbe84d870cdb64ea5c5f 599 SUPERFAMILY SSF47203 276 434 7.26E-29 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS10010 5d2c14d428d6bbe84d870cdb64ea5c5f 599 Pfam PF01756 Acyl-CoA oxidase 480 592 9.7E-12 T 06-07-2017 IPR002655 Acyl-CoA oxidase, C-terminal GO:0003997|GO:0005777|GO:0006635|GO:0055114 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS08470 38dc97fbd7178a722acdae84cceb342f 266 PIRSF PIRSF010219 8 233 2.1E-77 T 06-07-2017 IPR016566 Uncharacterised conserved protein UCP010219 SMD11_RS08470 38dc97fbd7178a722acdae84cceb342f 266 Pfam PF11361 Protein of unknown function (DUF3159) 33 219 1.3E-55 T 06-07-2017 IPR016566 Uncharacterised conserved protein UCP010219 SMD11_RS03855 ba54df31d2c0b07a584599189baed92b 374 Gene3D G3DSA:1.20.140.10 229 360 3.5E-29 T 06-07-2017 SMD11_RS03855 ba54df31d2c0b07a584599189baed92b 374 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 359 6.5E-24 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS03855 ba54df31d2c0b07a584599189baed92b 374 SUPERFAMILY SSF47203 230 364 1.01E-30 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS03855 ba54df31d2c0b07a584599189baed92b 374 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 120 1.2E-14 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS03855 ba54df31d2c0b07a584599189baed92b 374 Gene3D G3DSA:1.10.540.10 1 121 9.7E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS03855 ba54df31d2c0b07a584599189baed92b 374 SUPERFAMILY SSF56645 3 131 5.24E-17 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS03495 515ef5d2fd61cca8b1ca7510279cae03 354 Pfam PF10282 Lactonase, 7-bladed beta-propeller 15 353 3.0E-90 T 06-07-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 SMD11_RS03495 515ef5d2fd61cca8b1ca7510279cae03 354 Gene3D G3DSA:2.130.10.10 14 354 1.4E-93 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS03495 515ef5d2fd61cca8b1ca7510279cae03 354 SUPERFAMILY SSF51004 29 338 1.44E-43 T 06-07-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain SMD11_RS22015 74a1798a00610d86adc5094fc5e5e6c1 183 SUPERFAMILY SSF50249 5 120 9.6E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS22015 74a1798a00610d86adc5094fc5e5e6c1 183 Gene3D G3DSA:2.40.50.140 2 116 6.9E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS22015 74a1798a00610d86adc5094fc5e5e6c1 183 Pfam PF00436 Single-strand binding protein family 6 91 7.6E-18 T 06-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 SMD11_RS12980 74fa5d71657b3031722ac99f03048261 353 Pfam PF01266 FAD dependent oxidoreductase 1 345 9.5E-35 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD11_RS12980 74fa5d71657b3031722ac99f03048261 353 SUPERFAMILY SSF51905 1 206 4.86E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12980 74fa5d71657b3031722ac99f03048261 353 SUPERFAMILY SSF51905 308 349 4.86E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12980 74fa5d71657b3031722ac99f03048261 353 Gene3D G3DSA:3.30.9.10 73 131 7.7E-12 T 06-07-2017 SMD11_RS12980 74fa5d71657b3031722ac99f03048261 353 Gene3D G3DSA:3.30.9.10 205 296 7.7E-12 T 06-07-2017 SMD11_RS12980 74fa5d71657b3031722ac99f03048261 353 Gene3D G3DSA:3.50.50.60 308 348 2.0E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12980 74fa5d71657b3031722ac99f03048261 353 Gene3D G3DSA:3.50.50.60 1 72 2.0E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12980 74fa5d71657b3031722ac99f03048261 353 Gene3D G3DSA:3.50.50.60 132 204 2.0E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS10765 50d2e1f15f4c7832d41214732d505541 239 Pfam PF00196 Bacterial regulatory proteins, luxR family 174 230 1.7E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS10765 50d2e1f15f4c7832d41214732d505541 239 Gene3D G3DSA:1.10.10.10 143 237 9.7E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS10765 50d2e1f15f4c7832d41214732d505541 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 206 218 5.9E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS10765 50d2e1f15f4c7832d41214732d505541 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 190 5.9E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS10765 50d2e1f15f4c7832d41214732d505541 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 206 5.9E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS10765 50d2e1f15f4c7832d41214732d505541 239 SMART SM00421 173 230 3.6E-24 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS10765 50d2e1f15f4c7832d41214732d505541 239 SUPERFAMILY SSF46894 163 236 1.7E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS10765 50d2e1f15f4c7832d41214732d505541 239 Pfam PF00072 Response regulator receiver domain 24 135 3.6E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS10765 50d2e1f15f4c7832d41214732d505541 239 Gene3D G3DSA:3.40.50.2300 20 142 3.4E-34 T 06-07-2017 SMD11_RS10765 50d2e1f15f4c7832d41214732d505541 239 SMART SM00448 22 134 4.6E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS10765 50d2e1f15f4c7832d41214732d505541 239 ProSitePatterns PS00622 LuxR-type HTH domain signature. 190 217 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS10765 50d2e1f15f4c7832d41214732d505541 239 SUPERFAMILY SSF52172 21 152 7.4E-31 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS12905 bc7af873d07e54b3bb165dba73dbb4be 233 Gene3D G3DSA:1.10.10.10 3 70 2.1E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12905 bc7af873d07e54b3bb165dba73dbb4be 233 Pfam PF07729 FCD domain 100 219 1.7E-19 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS12905 bc7af873d07e54b3bb165dba73dbb4be 233 SMART SM00345 12 70 2.2E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS12905 bc7af873d07e54b3bb165dba73dbb4be 233 SUPERFAMILY SSF46785 5 74 1.25E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12905 bc7af873d07e54b3bb165dba73dbb4be 233 Gene3D G3DSA:1.20.120.530 86 221 1.1E-18 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS12905 bc7af873d07e54b3bb165dba73dbb4be 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 70 5.4E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS12905 bc7af873d07e54b3bb165dba73dbb4be 233 SUPERFAMILY SSF48008 96 226 2.04E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS12905 bc7af873d07e54b3bb165dba73dbb4be 233 SMART SM00895 99 223 5.1E-17 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS11520 87e65e135d1379ca39e99228b35d0860 483 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 80 434 1.8E-125 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 SMD11_RS11520 87e65e135d1379ca39e99228b35d0860 483 SUPERFAMILY SSF55486 79 434 1.25E-119 T 06-07-2017 SMD11_RS11520 87e65e135d1379ca39e99228b35d0860 483 Pfam PF10103 Zinicin-like metallopeptidase 80 432 3.3E-129 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 SMD11_RS20265 bda281e96bb4d5348fb3b999279d0c57 325 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 142 216 7.4E-25 T 06-07-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core SMD11_RS20265 bda281e96bb4d5348fb3b999279d0c57 325 Gene3D G3DSA:1.10.287.1080 123 193 1.8E-10 T 06-07-2017 SMD11_RS20265 bda281e96bb4d5348fb3b999279d0c57 325 SUPERFAMILY SSF101386 123 218 4.36E-20 T 06-07-2017 SMD11_RS03090 0f079dd18b5d78388443dfc5ef177a9f 107 SUPERFAMILY SSF54909 1 101 2.06E-24 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS03090 0f079dd18b5d78388443dfc5ef177a9f 107 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 69 6.9E-15 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain SMD11_RS03090 0f079dd18b5d78388443dfc5ef177a9f 107 Gene3D G3DSA:3.30.70.900 1 103 7.1E-33 T 06-07-2017 SMD11_RS05685 18684b8c8b73344e86e306d3cae60ed3 83 SUPERFAMILY SSF46785 8 80 9.43E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05685 18684b8c8b73344e86e306d3cae60ed3 83 Gene3D G3DSA:1.10.10.10 7 81 1.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05685 18684b8c8b73344e86e306d3cae60ed3 83 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 8.6E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS05685 18684b8c8b73344e86e306d3cae60ed3 83 SMART SM00345 18 77 4.7E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS05685 18684b8c8b73344e86e306d3cae60ed3 83 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 5.3E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS05685 18684b8c8b73344e86e306d3cae60ed3 83 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 5.3E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 141 746 1.6E-168 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 Pfam PF00403 Heavy-metal-associated domain 1 53 5.5E-9 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 ProSitePatterns PS01229 Hypothetical cof family signature 2. 644 666 - T 06-07-2017 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 Gene3D G3DSA:2.70.150.10 220 326 4.3E-22 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 Gene3D G3DSA:3.30.70.100 1 60 2.3E-18 T 06-07-2017 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 Gene3D G3DSA:3.40.50.1000 398 441 1.8E-46 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 Gene3D G3DSA:3.40.50.1000 572 712 1.8E-46 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 SUPERFAMILY SSF56784 423 443 8.97E-53 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 SUPERFAMILY SSF56784 541 744 8.97E-53 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 PRINTS PR00943 Copper-transporting ATPase signature 195 214 5.1E-6 T 06-07-2017 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 PRINTS PR00943 Copper-transporting ATPase signature 621 638 5.1E-6 T 06-07-2017 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 PRINTS PR00943 Copper-transporting ATPase signature 8 22 5.1E-6 T 06-07-2017 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 PRINTS PR00943 Copper-transporting ATPase signature 348 362 5.1E-6 T 06-07-2017 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 427 433 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 SUPERFAMILY SSF81660 446 579 1.21E-19 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 Gene3D G3DSA:3.40.1110.10 448 571 1.2E-14 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 667 679 4.1E-22 T 06-07-2017 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 425 439 4.1E-22 T 06-07-2017 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 275 289 4.1E-22 T 06-07-2017 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 663 4.1E-22 T 06-07-2017 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 591 601 4.1E-22 T 06-07-2017 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 SUPERFAMILY SSF55008 1 60 6.54E-14 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 Pfam PF00122 E1-E2 ATPase 199 416 5.3E-59 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 Pfam PF00702 haloacid dehalogenase-like hydrolase 421 658 9.6E-41 T 06-07-2017 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 201 445 9.7E-39 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 543 730 2.1E-38 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 SUPERFAMILY SSF81665 326 418 7.19E-9 T 06-07-2017 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 SUPERFAMILY SSF81665 198 229 7.19E-9 T 06-07-2017 SMD11_RS27765 4fa55aede353717826ad8dbe24876a3c 750 SUPERFAMILY SSF81653 231 325 2.09E-22 T 06-07-2017 SMD11_RS23065 72284c7ec7f4130ca7718bfed2cfd89f 129 SUPERFAMILY SSF52833 3 105 2.62E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS23065 72284c7ec7f4130ca7718bfed2cfd89f 129 Pfam PF00085 Thioredoxin 5 104 3.9E-27 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 SMD11_RS23065 72284c7ec7f4130ca7718bfed2cfd89f 129 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 104 1.2E-29 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMD11_RS23065 72284c7ec7f4130ca7718bfed2cfd89f 129 Gene3D G3DSA:3.40.30.10 2 104 1.3E-32 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS23065 72284c7ec7f4130ca7718bfed2cfd89f 129 ProSitePatterns PS00194 Thioredoxin family active site. 24 42 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 SMD11_RS23065 72284c7ec7f4130ca7718bfed2cfd89f 129 PRINTS PR00421 Thioredoxin family signature 31 40 2.2E-7 T 06-07-2017 SMD11_RS23065 72284c7ec7f4130ca7718bfed2cfd89f 129 PRINTS PR00421 Thioredoxin family signature 70 81 2.2E-7 T 06-07-2017 SMD11_RS23065 72284c7ec7f4130ca7718bfed2cfd89f 129 PRINTS PR00421 Thioredoxin family signature 23 31 2.2E-7 T 06-07-2017 SMD11_RS14270 e8ceaf18e7a6bcb2b5b3588ff9f0e773 605 PRINTS PR01607 Apyrase family signature 50 68 3.0E-16 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS14270 e8ceaf18e7a6bcb2b5b3588ff9f0e773 605 PRINTS PR01607 Apyrase family signature 296 319 3.0E-16 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS14270 e8ceaf18e7a6bcb2b5b3588ff9f0e773 605 PRINTS PR01607 Apyrase family signature 462 485 3.0E-16 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS14270 e8ceaf18e7a6bcb2b5b3588ff9f0e773 605 PRINTS PR01607 Apyrase family signature 538 557 3.0E-16 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS14270 e8ceaf18e7a6bcb2b5b3588ff9f0e773 605 SUPERFAMILY SSF55816 394 604 7.46E-45 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS14270 e8ceaf18e7a6bcb2b5b3588ff9f0e773 605 Gene3D G3DSA:3.90.780.10 396 604 2.1E-47 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS14270 e8ceaf18e7a6bcb2b5b3588ff9f0e773 605 SUPERFAMILY SSF56300 47 394 1.23E-63 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS14270 e8ceaf18e7a6bcb2b5b3588ff9f0e773 605 Gene3D G3DSA:3.60.21.10 45 393 8.0E-75 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS14270 e8ceaf18e7a6bcb2b5b3588ff9f0e773 605 Pfam PF00149 Calcineurin-like phosphoesterase 57 313 1.9E-4 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 SMD11_RS14270 e8ceaf18e7a6bcb2b5b3588ff9f0e773 605 Pfam PF02872 5'-nucleotidase, C-terminal domain 397 564 9.7E-37 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS03600 89212ee6d4b631691aed5e343f37fc6d 288 Pfam PF13622 Thioesterase-like superfamily 33 283 3.7E-59 T 06-07-2017 SMD11_RS03600 89212ee6d4b631691aed5e343f37fc6d 288 Gene3D G3DSA:3.10.129.10 4 116 5.3E-48 T 06-07-2017 IPR029069 HotDog domain SMD11_RS03600 89212ee6d4b631691aed5e343f37fc6d 288 SUPERFAMILY SSF54637 116 286 4.48E-46 T 06-07-2017 IPR029069 HotDog domain SMD11_RS03600 89212ee6d4b631691aed5e343f37fc6d 288 Gene3D G3DSA:3.10.129.10 124 286 6.6E-50 T 06-07-2017 IPR029069 HotDog domain SMD11_RS03600 89212ee6d4b631691aed5e343f37fc6d 288 SUPERFAMILY SSF54637 5 114 5.42E-42 T 06-07-2017 IPR029069 HotDog domain SMD11_RS13140 93c6fa819ad9d2889aae6714868e7b75 163 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 105 3.5E-19 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS13140 93c6fa819ad9d2889aae6714868e7b75 163 SUPERFAMILY SSF69118 16 157 1.2E-38 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS13140 93c6fa819ad9d2889aae6714868e7b75 163 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 40 88 6.7E-20 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS13140 93c6fa819ad9d2889aae6714868e7b75 163 Gene3D G3DSA:1.20.1290.10 15 158 2.2E-46 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS30895 a5520470886fa9508e5cab17d8c4c204 237 SMART SM00448 2 112 9.4E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS30895 a5520470886fa9508e5cab17d8c4c204 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 226 2.5E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS30895 a5520470886fa9508e5cab17d8c4c204 237 SUPERFAMILY SSF52172 1 119 4.55E-34 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS30895 a5520470886fa9508e5cab17d8c4c204 237 SMART SM00862 153 228 1.6E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS30895 a5520470886fa9508e5cab17d8c4c204 237 Pfam PF00072 Response regulator receiver domain 5 112 1.7E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS30895 a5520470886fa9508e5cab17d8c4c204 237 Gene3D G3DSA:3.40.50.2300 1 120 1.5E-32 T 06-07-2017 SMD11_RS30895 a5520470886fa9508e5cab17d8c4c204 237 SUPERFAMILY SSF46894 130 229 9.78E-26 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS30895 a5520470886fa9508e5cab17d8c4c204 237 Gene3D G3DSA:1.10.10.10 133 231 3.0E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02665 bd5686c14fa21c12ed0bce40f8f97065 302 Gene3D G3DSA:3.20.20.70 8 296 9.0E-84 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS02665 bd5686c14fa21c12ed0bce40f8f97065 302 SMART SM01130 11 297 3.4E-84 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS02665 bd5686c14fa21c12ed0bce40f8f97065 302 PIRSF PIRSF001365 9 299 2.1E-70 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS02665 bd5686c14fa21c12ed0bce40f8f97065 302 SUPERFAMILY SSF51569 10 295 1.36E-77 T 06-07-2017 SMD11_RS02665 bd5686c14fa21c12ed0bce40f8f97065 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 45 66 6.5E-8 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS02665 bd5686c14fa21c12ed0bce40f8f97065 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 6.5E-8 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS02665 bd5686c14fa21c12ed0bce40f8f97065 302 Pfam PF00701 Dihydrodipicolinate synthetase family 13 294 1.6E-48 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS27120 32eeef74d1dcd788db6218e6ab0abe66 186 SUPERFAMILY SSF54197 22 175 4.82E-42 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 SMD11_RS27120 32eeef74d1dcd788db6218e6ab0abe66 186 Gene3D G3DSA:3.30.428.10 45 183 2.0E-38 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 SMD11_RS27120 32eeef74d1dcd788db6218e6ab0abe66 186 Pfam PF01230 HIT domain 60 151 1.2E-11 T 06-07-2017 IPR001310 Histidine triad (HIT) protein SMD11_RS27080 9e7659cb88356957ec8d465cee6aea26 161 TIGRFAM TIGR02611 TIGR02611: TIGR02611 family protein 40 156 5.9E-39 T 06-07-2017 IPR013434 Conserved hypothetical protein CHP02611 SMD11_RS27080 9e7659cb88356957ec8d465cee6aea26 161 Pfam PF09656 Putative transmembrane protein (PGPGW) 60 112 7.2E-23 T 06-07-2017 IPR019099 Uncharacterised protein family PGPGW, transmembrane SMD11_RS03035 50b95c5cdb62bec7f095e27b946f74b2 284 Pfam PF13560 Helix-turn-helix domain 5 84 8.9E-15 T 06-07-2017 SMD11_RS03035 50b95c5cdb62bec7f095e27b946f74b2 284 Gene3D G3DSA:1.10.260.40 3 80 3.5E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS03035 50b95c5cdb62bec7f095e27b946f74b2 284 SUPERFAMILY SSF47413 29 79 2.49E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS03035 50b95c5cdb62bec7f095e27b946f74b2 284 SMART SM00530 9 81 3.2E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS13665 0c2ca514bbebbcc65d092861f9219b28 403 ProSitePatterns PS00216 Sugar transport proteins signature 1. 75 91 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS13665 0c2ca514bbebbcc65d092861f9219b28 403 SUPERFAMILY SSF103473 20 401 3.4E-39 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS13665 0c2ca514bbebbcc65d092861f9219b28 403 Gene3D G3DSA:1.20.1250.20 20 198 2.0E-20 T 06-07-2017 SMD11_RS13665 0c2ca514bbebbcc65d092861f9219b28 403 Gene3D G3DSA:1.20.1250.20 219 399 4.0E-9 T 06-07-2017 SMD11_RS13665 0c2ca514bbebbcc65d092861f9219b28 403 Pfam PF07690 Major Facilitator Superfamily 32 298 4.9E-18 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS33145 d8b65e1cd528cde00fc6cc62954274ba 592 Pfam PF05954 Phage late control gene D protein (GPD) 65 347 1.3E-11 T 06-07-2017 SMD11_RS33145 d8b65e1cd528cde00fc6cc62954274ba 592 SUPERFAMILY SSF69279 33 191 8.08E-18 T 06-07-2017 SMD11_RS33145 d8b65e1cd528cde00fc6cc62954274ba 592 Gene3D G3DSA:2.40.50.230 399 459 5.7E-13 T 06-07-2017 IPR006531 Gp5 N-terminal SMD11_RS33145 d8b65e1cd528cde00fc6cc62954274ba 592 SUPERFAMILY SSF69255 381 460 3.66E-14 T 06-07-2017 SMD11_RS09020 ecd540a489de375aea9659f21ccf0a54 227 Pfam PF00072 Response regulator receiver domain 7 119 1.5E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS09020 ecd540a489de375aea9659f21ccf0a54 227 Gene3D G3DSA:3.40.50.2300 3 128 6.6E-36 T 06-07-2017 SMD11_RS09020 ecd540a489de375aea9659f21ccf0a54 227 SMART SM00448 5 119 7.4E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS09020 ecd540a489de375aea9659f21ccf0a54 227 SUPERFAMILY SSF52172 3 146 9.82E-38 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS18475 e9e559b5f5b9c7a60d57384140113f89 639 Gene3D G3DSA:2.30.38.10 433 494 5.5E-20 T 06-07-2017 SMD11_RS18475 e9e559b5f5b9c7a60d57384140113f89 639 SUPERFAMILY SSF56801 185 322 4.06E-121 T 06-07-2017 SMD11_RS18475 e9e559b5f5b9c7a60d57384140113f89 639 SUPERFAMILY SSF56801 6 151 4.06E-121 T 06-07-2017 SMD11_RS18475 e9e559b5f5b9c7a60d57384140113f89 639 SUPERFAMILY SSF56801 373 631 4.06E-121 T 06-07-2017 SMD11_RS18475 e9e559b5f5b9c7a60d57384140113f89 639 Gene3D G3DSA:3.30.300.30 501 622 2.3E-4 T 06-07-2017 SMD11_RS18475 e9e559b5f5b9c7a60d57384140113f89 639 Gene3D G3DSA:3.40.50.980 204 224 2.3E-35 T 06-07-2017 SMD11_RS18475 e9e559b5f5b9c7a60d57384140113f89 639 Gene3D G3DSA:3.40.50.980 7 147 2.3E-35 T 06-07-2017 SMD11_RS18475 e9e559b5f5b9c7a60d57384140113f89 639 ProSitePatterns PS00455 Putative AMP-binding domain signature. 219 230 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS18475 e9e559b5f5b9c7a60d57384140113f89 639 Gene3D G3DSA:3.40.50.980 370 432 6.0E-28 T 06-07-2017 SMD11_RS18475 e9e559b5f5b9c7a60d57384140113f89 639 Gene3D G3DSA:3.40.50.980 225 317 6.0E-28 T 06-07-2017 SMD11_RS18475 e9e559b5f5b9c7a60d57384140113f89 639 Pfam PF00501 AMP-binding enzyme 14 503 1.2E-95 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS27160 d89dd0f6c65c74d8d24204467e5219f2 177 Pfam PF04011 LemA family 4 136 3.2E-5 T 06-07-2017 IPR007156 LemA SMD11_RS27160 d89dd0f6c65c74d8d24204467e5219f2 177 SUPERFAMILY SSF140478 22 136 1.31E-5 T 06-07-2017 IPR023353 LemA-like domain SMD11_RS27160 d89dd0f6c65c74d8d24204467e5219f2 177 Gene3D G3DSA:1.20.1440.20 13 135 1.0E-7 T 06-07-2017 IPR023353 LemA-like domain SMD11_RS21190 7d4a3aa343d54c98641df8a98f67e4d2 113 SUPERFAMILY SSF54593 6 97 9.65E-5 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS15260 7bb51b93b100fc76059e0cb942317163 539 SUPERFAMILY SSF53474 225 279 3.67E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15260 7bb51b93b100fc76059e0cb942317163 539 SUPERFAMILY SSF53474 382 526 3.67E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15260 7bb51b93b100fc76059e0cb942317163 539 SUPERFAMILY SSF53474 121 180 3.67E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15260 7bb51b93b100fc76059e0cb942317163 539 Gene3D G3DSA:3.40.50.1820 223 347 1.1E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15260 7bb51b93b100fc76059e0cb942317163 539 Gene3D G3DSA:3.40.50.1820 92 179 1.1E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15260 7bb51b93b100fc76059e0cb942317163 539 Gene3D G3DSA:3.40.50.1820 406 526 1.1E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15260 7bb51b93b100fc76059e0cb942317163 539 Pfam PF00561 alpha/beta hydrolase fold 128 511 2.3E-38 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS33560 8e6a337e2607d3125ff8c8feaeab2b0a 233 Gene3D G3DSA:3.40.50.1860 114 213 2.0E-34 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS33560 8e6a337e2607d3125ff8c8feaeab2b0a 233 SUPERFAMILY SSF53681 118 228 4.74E-33 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS33560 8e6a337e2607d3125ff8c8feaeab2b0a 233 Gene3D G3DSA:3.40.50.1860 1 113 1.2E-43 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS33560 8e6a337e2607d3125ff8c8feaeab2b0a 233 SUPERFAMILY SSF53681 1 116 2.62E-36 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS33560 8e6a337e2607d3125ff8c8feaeab2b0a 233 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 231 1.4E-72 T 06-07-2017 IPR004380 Aspartate racemase GO:0006520|GO:0016855 SMD11_RS33560 8e6a337e2607d3125ff8c8feaeab2b0a 233 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 223 2.9E-56 T 06-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 Gene3D G3DSA:1.20.58.100 426 542 1.7E-44 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 SUPERFAMILY SSF46977 446 584 8.37E-53 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 584 1.5E-247 T 06-07-2017 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 Gene3D G3DSA:3.50.50.60 350 420 6.1E-112 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 Gene3D G3DSA:3.50.50.60 2 242 6.1E-112 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 Pfam PF00890 FAD binding domain 7 400 8.3E-112 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 Pfam PF02910 Fumarate reductase flavoprotein C-term 454 584 1.1E-46 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 PIRSF PIRSF000171 1 578 4.7E-50 T 06-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 SUPERFAMILY SSF56425 236 354 1.03E-42 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 Gene3D G3DSA:3.90.700.10 243 349 2.5E-41 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 584 3.1E-278 T 06-07-2017 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 SUPERFAMILY SSF51905 2 259 1.68E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 SUPERFAMILY SSF51905 358 426 1.68E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 Gene3D G3DSA:4.10.80.40 543 580 3.1E-18 T 06-07-2017 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 06-07-2017 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 363 385 4.1E-5 T 06-07-2017 SMD11_RS13070 d925c259781725248af0e64b4643cdfb 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 4.1E-5 T 06-07-2017 SMD11_RS13605 6f9c0bf032b2105f6582f80c1ac93640 604 Pfam PF05506 Domain of unknown function (DUF756) 471 556 9.0E-18 T 06-07-2017 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 SMD11_RS13605 6f9c0bf032b2105f6582f80c1ac93640 604 Pfam PF04185 Phosphoesterase family 40 399 4.1E-110 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 SMD11_RS13605 6f9c0bf032b2105f6582f80c1ac93640 604 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 560 4.1E-194 T 06-07-2017 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 SMD11_RS02915 cb86fe9b691a934009bb0f775d8cb2c1 426 Pfam PF02342 TerD domain 2 168 7.9E-48 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS02915 cb86fe9b691a934009bb0f775d8cb2c1 426 PIRSF PIRSF037118 1 426 7.4E-170 T 06-07-2017 IPR017115 Tellurite resistance, TerA SMD11_RS02915 cb86fe9b691a934009bb0f775d8cb2c1 426 Gene3D G3DSA:2.60.60.30 15 166 1.6E-36 T 06-07-2017 SMD11_RS02915 cb86fe9b691a934009bb0f775d8cb2c1 426 Gene3D G3DSA:2.60.60.30 240 350 4.9E-5 T 06-07-2017 SMD11_RS17840 05e91a6d80411d7c8f969caf7bab58ad 299 Gene3D G3DSA:3.30.200.20 11 116 9.6E-43 T 06-07-2017 SMD11_RS17840 05e91a6d80411d7c8f969caf7bab58ad 299 ProSitePatterns PS01058 SAICAR synthetase signature 2. 204 212 - T 06-07-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS17840 05e91a6d80411d7c8f969caf7bab58ad 299 Gene3D G3DSA:3.30.470.20 117 247 1.3E-55 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS17840 05e91a6d80411d7c8f969caf7bab58ad 299 SUPERFAMILY SSF56104 12 298 2.16E-101 T 06-07-2017 SMD11_RS17840 05e91a6d80411d7c8f969caf7bab58ad 299 Pfam PF01259 SAICAR synthetase 18 267 2.4E-101 T 06-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS17840 05e91a6d80411d7c8f969caf7bab58ad 299 ProSitePatterns PS01057 SAICAR synthetase signature 1. 105 119 - T 06-07-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS17840 05e91a6d80411d7c8f969caf7bab58ad 299 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 16 295 26.048 T 06-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS17840 05e91a6d80411d7c8f969caf7bab58ad 299 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 18 298 1.5E-73 T 06-07-2017 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 SMD11_RS03355 e9030baad93053f20382f02608146005 309 Pfam PF13602 Zinc-binding dehydrogenase 186 307 1.3E-14 T 06-07-2017 SMD11_RS03355 e9030baad93053f20382f02608146005 309 SUPERFAMILY SSF50129 1 151 8.37E-32 T 06-07-2017 IPR011032 GroES-like SMD11_RS03355 e9030baad93053f20382f02608146005 309 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 5.6E-10 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS03355 e9030baad93053f20382f02608146005 309 SUPERFAMILY SSF51735 117 247 8.49E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03355 e9030baad93053f20382f02608146005 309 Gene3D G3DSA:3.90.180.10 1 149 1.3E-37 T 06-07-2017 IPR011032 GroES-like SMD11_RS03355 e9030baad93053f20382f02608146005 309 Gene3D G3DSA:3.40.50.720 150 239 4.1E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03355 e9030baad93053f20382f02608146005 309 SMART SM00829 10 307 1.9E-13 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS02405 54fd17abc1400788f5bdfcd4a7a96978 377 SUPERFAMILY SSF52266 176 370 1.83E-30 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS02405 54fd17abc1400788f5bdfcd4a7a96978 377 Gene3D G3DSA:3.40.50.1110 177 370 5.7E-20 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS02405 54fd17abc1400788f5bdfcd4a7a96978 377 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 178 363 2.3E-14 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS02290 25d7b2f4729dbb42dc198a150728a942 525 Pfam PF05199 GMC oxidoreductase 381 511 3.0E-36 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS02290 25d7b2f4729dbb42dc198a150728a942 525 PIRSF PIRSF000137 1 525 1.1E-150 T 06-07-2017 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 SMD11_RS02290 25d7b2f4729dbb42dc198a150728a942 525 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 82 105 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS02290 25d7b2f4729dbb42dc198a150728a942 525 SUPERFAMILY SSF54373 289 465 3.63E-36 T 06-07-2017 SMD11_RS02290 25d7b2f4729dbb42dc198a150728a942 525 Gene3D G3DSA:3.50.50.60 187 312 1.6E-120 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02290 25d7b2f4729dbb42dc198a150728a942 525 Gene3D G3DSA:3.50.50.60 458 517 1.6E-120 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02290 25d7b2f4729dbb42dc198a150728a942 525 Gene3D G3DSA:3.50.50.60 6 126 1.6E-120 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02290 25d7b2f4729dbb42dc198a150728a942 525 SUPERFAMILY SSF51905 5 287 5.67E-90 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02290 25d7b2f4729dbb42dc198a150728a942 525 SUPERFAMILY SSF51905 464 519 5.67E-90 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02290 25d7b2f4729dbb42dc198a150728a942 525 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 254 268 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS02290 25d7b2f4729dbb42dc198a150728a942 525 Pfam PF00732 GMC oxidoreductase 7 293 2.7E-93 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS32980 e2ddc66f0165140eb30685fdcfe05036 295 TIGRFAM TIGR02144 LysX_arch: lysine biosynthesis enzyme LysX 14 287 1.8E-83 T 06-07-2017 IPR011870 Lysine biosynthesis enzyme LysX GO:0003824|GO:0005524|GO:0009085 SMD11_RS32980 e2ddc66f0165140eb30685fdcfe05036 295 Pfam PF08443 RimK-like ATP-grasp domain 96 284 4.3E-28 T 06-07-2017 IPR013651 ATP-grasp fold, RimK-type SMD11_RS32980 e2ddc66f0165140eb30685fdcfe05036 295 Gene3D G3DSA:3.30.1490.20 100 165 1.8E-15 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS32980 e2ddc66f0165140eb30685fdcfe05036 295 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 14 285 2.6E-74 T 06-07-2017 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 SMD11_RS32980 e2ddc66f0165140eb30685fdcfe05036 295 Gene3D G3DSA:3.30.470.20 171 267 7.4E-17 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS32980 e2ddc66f0165140eb30685fdcfe05036 295 Gene3D G3DSA:3.40.50.20 14 99 4.0E-22 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS32980 e2ddc66f0165140eb30685fdcfe05036 295 SUPERFAMILY SSF56059 97 286 3.36E-41 T 06-07-2017 SMD11_RS32980 e2ddc66f0165140eb30685fdcfe05036 295 SUPERFAMILY SSF52440 14 96 5.47E-14 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS30440 a2e57dbebaaf6b510a51377e657624f4 500 Gene3D G3DSA:3.30.9.10 316 329 1.2E-7 T 06-07-2017 SMD11_RS30440 a2e57dbebaaf6b510a51377e657624f4 500 Gene3D G3DSA:3.30.9.10 160 261 1.2E-7 T 06-07-2017 SMD11_RS30440 a2e57dbebaaf6b510a51377e657624f4 500 Pfam PF01494 FAD binding domain 3 332 8.1E-85 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS30440 a2e57dbebaaf6b510a51377e657624f4 500 Gene3D G3DSA:3.50.50.60 2 159 4.0E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS30440 a2e57dbebaaf6b510a51377e657624f4 500 Gene3D G3DSA:3.50.50.60 266 305 4.0E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS30440 a2e57dbebaaf6b510a51377e657624f4 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 319 1.0E-42 T 06-07-2017 SMD11_RS30440 a2e57dbebaaf6b510a51377e657624f4 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 268 283 1.0E-42 T 06-07-2017 SMD11_RS30440 a2e57dbebaaf6b510a51377e657624f4 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.0E-42 T 06-07-2017 SMD11_RS30440 a2e57dbebaaf6b510a51377e657624f4 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 299 1.0E-42 T 06-07-2017 SMD11_RS30440 a2e57dbebaaf6b510a51377e657624f4 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 319 335 1.0E-42 T 06-07-2017 SMD11_RS30440 a2e57dbebaaf6b510a51377e657624f4 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 1.0E-42 T 06-07-2017 SMD11_RS30440 a2e57dbebaaf6b510a51377e657624f4 500 SUPERFAMILY SSF51905 1 169 1.02E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS30440 a2e57dbebaaf6b510a51377e657624f4 500 SUPERFAMILY SSF51905 264 344 1.02E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29920 af5a735ba90a8cc97ab8c9934ff42ffe 393 SUPERFAMILY SSF55486 67 392 3.3E-44 T 06-07-2017 SMD11_RS29920 af5a735ba90a8cc97ab8c9934ff42ffe 393 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 222 392 1.3E-31 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 SMD11_RS29920 af5a735ba90a8cc97ab8c9934ff42ffe 393 Gene3D G3DSA:3.10.170.10 69 194 7.0E-24 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS29920 af5a735ba90a8cc97ab8c9934ff42ffe 393 Gene3D G3DSA:1.10.390.10 222 392 1.1E-32 T 06-07-2017 SMD11_RS29920 af5a735ba90a8cc97ab8c9934ff42ffe 393 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 69 205 7.6E-27 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS03430 ee15f789d7a7cb220783c839845b26e2 210 Pfam PF08281 Sigma-70, region 4 134 183 4.2E-16 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS03430 ee15f789d7a7cb220783c839845b26e2 210 Gene3D G3DSA:1.10.10.10 125 189 1.9E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03430 ee15f789d7a7cb220783c839845b26e2 210 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 185 1.8E-23 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS03430 ee15f789d7a7cb220783c839845b26e2 210 Gene3D G3DSA:1.10.1740.10 16 115 1.5E-23 T 06-07-2017 SMD11_RS03430 ee15f789d7a7cb220783c839845b26e2 210 Pfam PF04542 Sigma-70 region 2 31 99 1.9E-11 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS03430 ee15f789d7a7cb220783c839845b26e2 210 SUPERFAMILY SSF88659 125 186 1.64E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS03430 ee15f789d7a7cb220783c839845b26e2 210 SUPERFAMILY SSF88946 8 113 4.45E-20 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS04475 0953283293e8ce2be0e0c8f43bd101ce 453 Pfam PF00107 Zinc-binding dehydrogenase 236 380 2.4E-39 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS04475 0953283293e8ce2be0e0c8f43bd101ce 453 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 33 428 4.7E-184 T 06-07-2017 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 SMD11_RS04475 0953283293e8ce2be0e0c8f43bd101ce 453 SUPERFAMILY SSF51735 198 394 8.0E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04475 0953283293e8ce2be0e0c8f43bd101ce 453 SUPERFAMILY SSF50129 47 230 5.9E-29 T 06-07-2017 IPR011032 GroES-like SMD11_RS04475 0953283293e8ce2be0e0c8f43bd101ce 453 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 115 189 6.4E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS04475 0953283293e8ce2be0e0c8f43bd101ce 453 SMART SM00829 49 415 2.0E-10 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS04475 0953283293e8ce2be0e0c8f43bd101ce 453 Gene3D G3DSA:3.40.50.720 232 364 3.3E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04475 0953283293e8ce2be0e0c8f43bd101ce 453 Gene3D G3DSA:3.90.180.10 46 231 5.4E-31 T 06-07-2017 IPR011032 GroES-like SMD11_RS30485 78045ed63b7b313af6a686858543117f 156 SUPERFAMILY SSF55811 11 129 3.11E-18 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS30485 78045ed63b7b313af6a686858543117f 156 Gene3D G3DSA:3.90.79.10 9 125 2.5E-16 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS30485 78045ed63b7b313af6a686858543117f 156 Pfam PF00293 NUDIX domain 10 120 8.3E-9 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS11435 1a9c1b5e7e934ab79873329fc2b2604a 323 SUPERFAMILY SSF161098 100 288 2.88E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11435 1a9c1b5e7e934ab79873329fc2b2604a 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 303 8.2E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11435 1a9c1b5e7e934ab79873329fc2b2604a 323 Gene3D G3DSA:1.10.3720.10 95 303 3.3E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11435 1a9c1b5e7e934ab79873329fc2b2604a 323 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 32 74 3.4E-8 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD11_RS05100 30f43b742ebe2bcd30b96f9b43ea056d 377 SUPERFAMILY SSF56601 26 375 9.29E-71 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS05100 30f43b742ebe2bcd30b96f9b43ea056d 377 Gene3D G3DSA:3.40.710.10 42 360 1.1E-72 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS05100 30f43b742ebe2bcd30b96f9b43ea056d 377 Pfam PF00144 Beta-lactamase 36 354 6.0E-56 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS00205 30f43b742ebe2bcd30b96f9b43ea056d 377 SUPERFAMILY SSF56601 26 375 9.29E-71 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS00205 30f43b742ebe2bcd30b96f9b43ea056d 377 Gene3D G3DSA:3.40.710.10 42 360 1.1E-72 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS00205 30f43b742ebe2bcd30b96f9b43ea056d 377 Pfam PF00144 Beta-lactamase 36 354 6.0E-56 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS12950 6a9f198353f790e3edf61d713a8aa98d 323 Pfam PF12833 Helix-turn-helix domain 230 308 3.2E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS12950 6a9f198353f790e3edf61d713a8aa98d 323 Gene3D G3DSA:3.40.50.880 2 190 1.3E-48 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS12950 6a9f198353f790e3edf61d713a8aa98d 323 SUPERFAMILY SSF46689 210 257 5.91E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS12950 6a9f198353f790e3edf61d713a8aa98d 323 Gene3D G3DSA:1.10.10.60 207 263 3.4E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS12950 6a9f198353f790e3edf61d713a8aa98d 323 Gene3D G3DSA:1.10.10.60 264 314 8.4E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS12950 6a9f198353f790e3edf61d713a8aa98d 323 SUPERFAMILY SSF52317 1 190 3.44E-44 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS12950 6a9f198353f790e3edf61d713a8aa98d 323 SMART SM00342 224 307 2.3E-29 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS12950 6a9f198353f790e3edf61d713a8aa98d 323 Pfam PF01965 DJ-1/PfpI family 63 169 2.2E-15 T 06-07-2017 IPR002818 DJ-1/PfpI SMD11_RS12950 6a9f198353f790e3edf61d713a8aa98d 323 SUPERFAMILY SSF46689 261 311 3.0E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS16650 011c5b967dd5bf00c92a93e957416213 298 Pfam PF03466 LysR substrate binding domain 88 294 2.1E-22 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS16650 011c5b967dd5bf00c92a93e957416213 298 Gene3D G3DSA:3.40.190.10 83 161 2.2E-6 T 06-07-2017 SMD11_RS16650 011c5b967dd5bf00c92a93e957416213 298 Gene3D G3DSA:3.40.190.10 286 291 2.2E-6 T 06-07-2017 SMD11_RS16650 011c5b967dd5bf00c92a93e957416213 298 Gene3D G3DSA:1.10.10.10 1 79 1.0E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16650 011c5b967dd5bf00c92a93e957416213 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.3E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS16650 011c5b967dd5bf00c92a93e957416213 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.3E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS16650 011c5b967dd5bf00c92a93e957416213 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.3E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS16650 011c5b967dd5bf00c92a93e957416213 298 SUPERFAMILY SSF53850 90 295 1.99E-22 T 06-07-2017 SMD11_RS16650 011c5b967dd5bf00c92a93e957416213 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 7.1E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS16650 011c5b967dd5bf00c92a93e957416213 298 Gene3D G3DSA:3.40.190.10 162 261 1.9E-15 T 06-07-2017 SMD11_RS16650 011c5b967dd5bf00c92a93e957416213 298 SUPERFAMILY SSF46785 1 77 2.63E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 TIGRFAM TIGR00593 pola: DNA polymerase I 24 910 1.6E-291 T 06-07-2017 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 SMART SM00474 330 501 5.0E-4 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 SMART SM00279 194 229 1.6E-14 T 06-07-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 737 762 2.1E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 713 726 2.1E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 796 807 2.1E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 828 844 2.1E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 858 871 2.1E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 637 659 2.1E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 774 785 2.1E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 683 706 2.1E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 660 675 2.1E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 SMART SM00482 668 875 5.7E-113 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 Pfam PF00476 DNA polymerase family A 535 908 3.7E-140 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 SUPERFAMILY SSF53098 333 502 1.67E-29 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 Gene3D G3DSA:1.20.1060.10 527 645 1.3E-32 T 06-07-2017 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 SMART SM00475 20 282 2.2E-143 T 06-07-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 SUPERFAMILY SSF56672 508 909 2.33E-136 T 06-07-2017 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 Gene3D G3DSA:3.40.50.1010 23 206 6.9E-68 T 06-07-2017 IPR029060 PIN domain-like SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 SUPERFAMILY SSF88723 21 191 1.65E-53 T 06-07-2017 IPR029060 PIN domain-like SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 23 191 1.7E-54 T 06-07-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 SUPERFAMILY SSF47807 192 300 3.89E-28 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 193 281 4.8E-26 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 Gene3D G3DSA:3.30.420.10 333 525 9.5E-48 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 Gene3D G3DSA:1.10.150.20 695 801 3.5E-31 T 06-07-2017 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 Gene3D G3DSA:3.30.70.370 802 910 8.2E-64 T 06-07-2017 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 Gene3D G3DSA:3.30.70.370 646 694 8.2E-64 T 06-07-2017 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 Gene3D G3DSA:1.10.150.20 207 266 2.0E-24 T 06-07-2017 SMD11_RS24950 c3788adf81e391441d80257274c87c2a 912 Pfam PF01612 3'-5' exonuclease 363 460 7.5E-5 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SMD11_RS20480 97bd8ee792838b83d317d6040a9cba8a 283 Gene3D G3DSA:3.40.50.10490 73 241 8.5E-7 T 06-07-2017 SMD11_RS20480 97bd8ee792838b83d317d6040a9cba8a 283 Gene3D G3DSA:1.10.10.10 21 72 3.4E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20480 97bd8ee792838b83d317d6040a9cba8a 283 SUPERFAMILY SSF53697 94 243 6.9E-9 T 06-07-2017 SMD11_RS20480 97bd8ee792838b83d317d6040a9cba8a 283 SUPERFAMILY SSF46689 21 83 3.23E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS20480 97bd8ee792838b83d317d6040a9cba8a 283 Pfam PF01418 Helix-turn-helix domain, rpiR family 20 80 1.6E-11 T 06-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SMD11_RS04845 a5d6190ff6dc622c39e922e308597170 130 Gene3D G3DSA:3.40.47.10 80 126 3.8E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS04845 a5d6190ff6dc622c39e922e308597170 130 Gene3D G3DSA:3.40.47.10 2 42 8.1E-4 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29430 28260f4dda2b6f8b271a090de7740470 299 Gene3D G3DSA:1.10.10.10 1 85 2.6E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS29430 28260f4dda2b6f8b271a090de7740470 299 Gene3D G3DSA:3.40.190.10 171 263 6.3E-20 T 06-07-2017 SMD11_RS29430 28260f4dda2b6f8b271a090de7740470 299 SUPERFAMILY SSF46785 1 85 1.04E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS29430 28260f4dda2b6f8b271a090de7740470 299 Gene3D G3DSA:3.40.190.10 91 170 9.5E-17 T 06-07-2017 SMD11_RS29430 28260f4dda2b6f8b271a090de7740470 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS29430 28260f4dda2b6f8b271a090de7740470 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS29430 28260f4dda2b6f8b271a090de7740470 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS29430 28260f4dda2b6f8b271a090de7740470 299 Pfam PF03466 LysR substrate binding domain 89 291 6.9E-43 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS29430 28260f4dda2b6f8b271a090de7740470 299 SUPERFAMILY SSF53850 90 291 1.25E-40 T 06-07-2017 SMD11_RS29430 28260f4dda2b6f8b271a090de7740470 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.7E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS27155 f8a237a98c07e4e074232dc3fa3995bd 390 Pfam PF13692 Glycosyl transferases group 1 192 331 3.5E-30 T 06-07-2017 SMD11_RS27155 f8a237a98c07e4e074232dc3fa3995bd 390 Gene3D G3DSA:3.40.50.2000 165 343 1.6E-26 T 06-07-2017 SMD11_RS27155 f8a237a98c07e4e074232dc3fa3995bd 390 SUPERFAMILY SSF53756 2 367 2.49E-86 T 06-07-2017 SMD11_RS27155 f8a237a98c07e4e074232dc3fa3995bd 390 Pfam PF13439 Glycosyltransferase Family 4 14 173 3.0E-34 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 SMD11_RS29245 b935f8b3291ae03161a223f506cf5403 259 Pfam PF01522 Polysaccharide deacetylase 66 176 2.9E-19 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS29245 b935f8b3291ae03161a223f506cf5403 259 SUPERFAMILY SSF88713 60 244 8.06E-39 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS29245 b935f8b3291ae03161a223f506cf5403 259 Gene3D G3DSA:3.20.20.370 31 243 6.7E-35 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS18630 584f3edc4d2b904e687919630bc6f346 336 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 212 224 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 SMD11_RS18630 584f3edc4d2b904e687919630bc6f346 336 Gene3D G3DSA:1.10.600.10 16 334 1.8E-88 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS18630 584f3edc4d2b904e687919630bc6f346 336 SUPERFAMILY SSF48576 20 334 1.37E-81 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS18630 584f3edc4d2b904e687919630bc6f346 336 Pfam PF00348 Polyprenyl synthetase 42 256 1.4E-57 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 SMD11_RS07725 9e37dbacb9523d053ed18ad8c7be8490 148 Gene3D G3DSA:1.10.10.10 77 141 1.4E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07725 9e37dbacb9523d053ed18ad8c7be8490 148 Gene3D G3DSA:1.10.10.10 5 73 5.3E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07725 9e37dbacb9523d053ed18ad8c7be8490 148 SMART SM00345 79 138 3.3E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS07725 9e37dbacb9523d053ed18ad8c7be8490 148 SMART SM00345 13 70 2.8E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS07725 9e37dbacb9523d053ed18ad8c7be8490 148 SUPERFAMILY SSF46785 4 73 3.31E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07725 9e37dbacb9523d053ed18ad8c7be8490 148 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 70 2.2E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS07725 9e37dbacb9523d053ed18ad8c7be8490 148 Pfam PF00392 Bacterial regulatory proteins, gntR family 82 134 2.8E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS07725 9e37dbacb9523d053ed18ad8c7be8490 148 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 98 112 9.1E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS07725 9e37dbacb9523d053ed18ad8c7be8490 148 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 112 128 9.1E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS07725 9e37dbacb9523d053ed18ad8c7be8490 148 SUPERFAMILY SSF46785 76 142 1.86E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28245 78fd92326cfd15e71f6dbc6eac63a970 331 Pfam PF00892 EamA-like transporter family 46 172 1.6E-17 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS28245 78fd92326cfd15e71f6dbc6eac63a970 331 Pfam PF00892 EamA-like transporter family 185 319 1.9E-18 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS28245 78fd92326cfd15e71f6dbc6eac63a970 331 SUPERFAMILY SSF103481 222 322 9.02E-13 T 06-07-2017 SMD11_RS28245 78fd92326cfd15e71f6dbc6eac63a970 331 SUPERFAMILY SSF103481 76 173 2.48E-10 T 06-07-2017 SMD11_RS22590 2b05dc6b149c60fa34c86edce3d5db26 88 Gene3D G3DSA:1.20.58.110 3 87 5.7E-27 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS22590 2b05dc6b149c60fa34c86edce3d5db26 88 SUPERFAMILY SSF46992 3 86 1.03E-25 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS22590 2b05dc6b149c60fa34c86edce3d5db26 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 83 5.8E-21 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS22590 2b05dc6b149c60fa34c86edce3d5db26 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.284 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS22590 2b05dc6b149c60fa34c86edce3d5db26 88 Pfam PF01649 Ribosomal protein S20 2 82 3.0E-25 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS22590 2b05dc6b149c60fa34c86edce3d5db26 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 68 5.0E-8 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS03010 348e5e1ff70a0ef766205698c8b18880 342 Gene3D G3DSA:3.30.360.10 155 310 5.4E-58 T 06-07-2017 SMD11_RS03010 348e5e1ff70a0ef766205698c8b18880 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 313 1.6E-22 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS03010 348e5e1ff70a0ef766205698c8b18880 342 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 06-07-2017 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS03010 348e5e1ff70a0ef766205698c8b18880 342 SUPERFAMILY SSF51735 3 171 1.06E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03010 348e5e1ff70a0ef766205698c8b18880 342 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 336 39.283 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS03010 348e5e1ff70a0ef766205698c8b18880 342 SMART SM00859 4 136 5.6E-41 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD11_RS03010 348e5e1ff70a0ef766205698c8b18880 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 136 2.2E-26 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD11_RS03010 348e5e1ff70a0ef766205698c8b18880 342 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 4 342 3.4E-117 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS03010 348e5e1ff70a0ef766205698c8b18880 342 SUPERFAMILY SSF55347 146 310 2.83E-47 T 06-07-2017 SMD11_RS03010 348e5e1ff70a0ef766205698c8b18880 342 Gene3D G3DSA:3.40.50.720 1 154 1.3E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18570 4a128d44d6876329e60b9d715ea3b9a8 455 Pfam PF00146 NADH dehydrogenase 25 348 8.8E-124 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18570 4a128d44d6876329e60b9d715ea3b9a8 455 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 64 79 - T 06-07-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18570 4a128d44d6876329e60b9d715ea3b9a8 455 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 231 244 - T 06-07-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18570 4a128d44d6876329e60b9d715ea3b9a8 455 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 18 355 24.456 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS07715 12969ac21141c5e14d4d93d0e6cfed39 157 SUPERFAMILY SSF55811 6 148 2.71E-33 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS07715 12969ac21141c5e14d4d93d0e6cfed39 157 Pfam PF00293 NUDIX domain 20 137 5.2E-18 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS07715 12969ac21141c5e14d4d93d0e6cfed39 157 Gene3D G3DSA:3.90.79.10 5 145 4.2E-35 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS07715 12969ac21141c5e14d4d93d0e6cfed39 157 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD11_RS07715 12969ac21141c5e14d4d93d0e6cfed39 157 PRINTS PR00502 NUDIX hydrolase family signature 58 73 4.4E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS07715 12969ac21141c5e14d4d93d0e6cfed39 157 PRINTS PR00502 NUDIX hydrolase family signature 44 58 4.4E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS05265 cb07b8e6c05d1a26a61a9b3d52ed3f96 188 Gene3D G3DSA:1.20.1290.10 32 178 3.0E-34 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS05265 cb07b8e6c05d1a26a61a9b3d52ed3f96 188 Pfam PF02627 Carboxymuconolactone decarboxylase family 54 123 3.7E-10 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS05265 cb07b8e6c05d1a26a61a9b3d52ed3f96 188 SUPERFAMILY SSF69118 5 175 4.71E-36 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS11130 1930d8e7064ae89f392decdec041aedf 296 Gene3D G3DSA:1.10.10.10 4 85 6.9E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11130 1930d8e7064ae89f392decdec041aedf 296 Gene3D G3DSA:3.40.190.10 86 184 6.2E-17 T 06-07-2017 SMD11_RS11130 1930d8e7064ae89f392decdec041aedf 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 8.2E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS11130 1930d8e7064ae89f392decdec041aedf 296 Pfam PF03466 LysR substrate binding domain 90 294 4.1E-23 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS11130 1930d8e7064ae89f392decdec041aedf 296 SUPERFAMILY SSF46785 4 87 5.54E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11130 1930d8e7064ae89f392decdec041aedf 296 SUPERFAMILY SSF53850 91 295 8.15E-22 T 06-07-2017 SMD11_RS11130 1930d8e7064ae89f392decdec041aedf 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.9E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS11130 1930d8e7064ae89f392decdec041aedf 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.9E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS11130 1930d8e7064ae89f392decdec041aedf 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.9E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS11130 1930d8e7064ae89f392decdec041aedf 296 Gene3D G3DSA:3.40.190.10 185 265 3.2E-5 T 06-07-2017 SMD11_RS04595 a39eef6ec9249f160ebd98070fccea1f 468 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 423 3.1E-70 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS04595 a39eef6ec9249f160ebd98070fccea1f 468 Gene3D G3DSA:1.20.1250.20 272 461 6.7E-16 T 06-07-2017 SMD11_RS04595 a39eef6ec9249f160ebd98070fccea1f 468 Pfam PF07690 Major Facilitator Superfamily 26 418 2.6E-36 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS04595 a39eef6ec9249f160ebd98070fccea1f 468 Gene3D G3DSA:1.20.1250.20 19 200 6.4E-29 T 06-07-2017 SMD11_RS04595 a39eef6ec9249f160ebd98070fccea1f 468 SUPERFAMILY SSF103473 14 203 4.19E-56 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS04595 a39eef6ec9249f160ebd98070fccea1f 468 SUPERFAMILY SSF103473 255 464 4.19E-56 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS04690 b466bf737a87244d19db6ba2f15d0793 371 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 3 291 1.8E-86 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMD11_RS04690 b466bf737a87244d19db6ba2f15d0793 371 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 371 75.812 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMD11_RS04690 b466bf737a87244d19db6ba2f15d0793 371 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 5 286 1.8E-56 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMD11_RS04690 b466bf737a87244d19db6ba2f15d0793 371 SUPERFAMILY SSF55931 2 356 1.55E-87 T 06-07-2017 SMD11_RS12535 da1f98edae81ea0ada054a9225ea237f 188 SUPERFAMILY SSF53335 26 182 8.52E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS12535 da1f98edae81ea0ada054a9225ea237f 188 Gene3D G3DSA:3.40.50.150 20 175 8.7E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS12535 da1f98edae81ea0ada054a9225ea237f 188 Pfam PF08241 Methyltransferase domain 39 132 1.5E-16 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 SUPERFAMILY SSF53335 224 375 3.57E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 SUPERFAMILY SSF47336 657 729 1.44E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Pfam PF08242 Methyltransferase domain 261 360 4.0E-9 T 06-07-2017 IPR013217 Methyltransferase type 12 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 SUPERFAMILY SSF56801 1178 1746 6.41E-161 T 06-07-2017 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Gene3D G3DSA:2.30.38.10 74 133 4.4E-19 T 06-07-2017 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Gene3D G3DSA:2.30.38.10 1537 1614 2.0E-28 T 06-07-2017 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 SUPERFAMILY SSF51735 1850 2128 3.79E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 SMART SM00823 Phosphopantetheine attachment site 1733 1802 2.4E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 SMART SM00823 Phosphopantetheine attachment site 664 733 1.3E-10 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Gene3D G3DSA:3.30.300.30 1620 1737 3.2E-42 T 06-07-2017 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Gene3D G3DSA:3.30.300.30 606 667 2.6E-39 T 06-07-2017 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Gene3D G3DSA:3.30.300.30 138 195 2.6E-39 T 06-07-2017 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 SUPERFAMILY SSF52777 936 1182 3.89E-61 T 06-07-2017 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Gene3D G3DSA:3.40.50.720 1850 2149 1.9E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Gene3D G3DSA:3.40.50.980 1213 1397 2.2E-45 T 06-07-2017 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 ProSitePatterns PS00012 Phosphopantetheine attachment site. 688 703 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 SUPERFAMILY SSF47336 1726 1798 3.8E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Gene3D G3DSA:3.40.50.980 1399 1536 1.3E-38 T 06-07-2017 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 SUPERFAMILY SSF52777 751 923 1.33E-51 T 06-07-2017 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Pfam PF00501 AMP-binding enzyme 1218 1624 2.8E-94 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Pfam PF00501 AMP-binding enzyme 69 143 1.2E-19 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Pfam PF13745 HxxPF-repeated domain 1069 1165 4.8E-31 T 06-07-2017 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1757 1772 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Pfam PF00668 Condensation domain 748 1047 1.7E-66 T 06-07-2017 IPR001242 Condensation domain SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Pfam PF00550 Phosphopantetheine attachment site 1736 1798 1.9E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Pfam PF00550 Phosphopantetheine attachment site 666 729 3.3E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 SUPERFAMILY SSF56801 601 677 1.09E-63 T 06-07-2017 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 SUPERFAMILY SSF56801 74 197 1.09E-63 T 06-07-2017 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1244 1648 1.4E-130 T 06-07-2017 IPR010071 Amino acid adenylation domain SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Gene3D G3DSA:1.10.1200.10 1738 1804 3.9E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Gene3D G3DSA:1.10.1200.10 668 734 5.2E-28 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 1850 2221 2.1E-91 T 06-07-2017 IPR010080 Thioester reductase-like domain SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Pfam PF07993 Male sterility protein 1853 2094 7.7E-63 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Pfam PF13193 AMP-binding enzyme C-terminal domain 151 190 2.5E-6 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Pfam PF13193 AMP-binding enzyme C-terminal domain 1632 1708 2.6E-15 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS06700 72881dea6aee68d0e0b31ce3b2c4424c 2228 Gene3D G3DSA:3.40.50.150 224 366 1.1E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS22105 0d8f139d84136de8145ec984bed87bb4 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 280 5.8E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS22105 0d8f139d84136de8145ec984bed87bb4 287 SUPERFAMILY SSF161098 15 287 1.16E-73 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS22105 0d8f139d84136de8145ec984bed87bb4 287 Gene3D G3DSA:1.10.3720.10 13 274 3.3E-71 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS33760 e858e08ab5d67f1f5eb50a69f253808f 675 SUPERFAMILY SSF52540 344 634 7.16E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS33760 e858e08ab5d67f1f5eb50a69f253808f 675 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 465 483 3.2E-27 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 SMD11_RS33760 e858e08ab5d67f1f5eb50a69f253808f 675 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 498 512 3.2E-27 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 SMD11_RS33760 e858e08ab5d67f1f5eb50a69f253808f 675 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 436 454 3.2E-27 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 SMD11_RS33760 e858e08ab5d67f1f5eb50a69f253808f 675 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 391 409 3.2E-27 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 SMD11_RS33760 e858e08ab5d67f1f5eb50a69f253808f 675 SMART SM00382 387 530 1.1E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS33760 e858e08ab5d67f1f5eb50a69f253808f 675 SMART SM01086 570 666 4.6E-6 T 06-07-2017 IPR019489 Clp ATPase, C-terminal SMD11_RS33760 e858e08ab5d67f1f5eb50a69f253808f 675 Gene3D G3DSA:3.40.50.300 350 581 6.9E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS33760 e858e08ab5d67f1f5eb50a69f253808f 675 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 571 651 5.8E-8 T 06-07-2017 IPR019489 Clp ATPase, C-terminal SMD11_RS33760 e858e08ab5d67f1f5eb50a69f253808f 675 Gene3D G3DSA:1.10.8.60 582 656 3.1E-6 T 06-07-2017 SMD11_RS33760 e858e08ab5d67f1f5eb50a69f253808f 675 Pfam PF07724 AAA domain (Cdc48 subfamily) 387 560 7.0E-35 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS18575 1698c24223a0e44215518761d749d1ca 196 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 3 145 28.478 T 06-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18575 1698c24223a0e44215518761d749d1ca 196 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 12 139 1.2E-44 T 06-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18575 1698c24223a0e44215518761d749d1ca 196 SUPERFAMILY SSF54862 29 151 1.09E-28 T 06-07-2017 SMD11_RS18575 1698c24223a0e44215518761d749d1ca 196 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 56 67 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD11_RS18575 1698c24223a0e44215518761d749d1ca 196 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD11_RS18575 1698c24223a0e44215518761d749d1ca 196 Pfam PF12838 4Fe-4S dicluster domain 55 115 1.3E-11 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD11_RS18575 1698c24223a0e44215518761d749d1ca 196 Gene3D G3DSA:1.10.1060.10 12 128 3.2E-20 T 06-07-2017 SMD11_RS20425 0643fa100a2fa91d587c66a5ff637166 529 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 511 1.6E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS20425 0643fa100a2fa91d587c66a5ff637166 529 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS20425 0643fa100a2fa91d587c66a5ff637166 529 Gene3D G3DSA:3.40.50.980 182 341 7.4E-47 T 06-07-2017 SMD11_RS20425 0643fa100a2fa91d587c66a5ff637166 529 Gene3D G3DSA:3.30.300.30 420 523 2.5E-30 T 06-07-2017 SMD11_RS20425 0643fa100a2fa91d587c66a5ff637166 529 SUPERFAMILY SSF56801 15 523 1.02E-150 T 06-07-2017 SMD11_RS20425 0643fa100a2fa91d587c66a5ff637166 529 Pfam PF00501 AMP-binding enzyme 25 423 6.0E-104 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS20425 0643fa100a2fa91d587c66a5ff637166 529 Gene3D G3DSA:2.30.38.10 342 413 1.2E-33 T 06-07-2017 SMD11_RS20425 0643fa100a2fa91d587c66a5ff637166 529 Gene3D G3DSA:3.40.50.980 20 181 2.4E-32 T 06-07-2017 SMD11_RS01815 5ad05a7a72d4b7933e4a7e179ef013da 194 SUPERFAMILY SSF53597 2 190 2.09E-23 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD11_RS01815 5ad05a7a72d4b7933e4a7e179ef013da 194 Pfam PF01872 RibD C-terminal domain 3 187 2.5E-6 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD11_RS01815 5ad05a7a72d4b7933e4a7e179ef013da 194 Gene3D G3DSA:3.40.430.10 3 192 9.8E-25 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD11_RS25430 e11b73767e60864b45ea55cfbe228362 532 SUPERFAMILY SSF52540 330 522 3.31E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25430 e11b73767e60864b45ea55cfbe228362 532 SMART SM00382 26 232 1.3E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS25430 e11b73767e60864b45ea55cfbe228362 532 SMART SM00382 350 516 9.1E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS25430 e11b73767e60864b45ea55cfbe228362 532 Pfam PF00005 ABC transporter 342 471 2.1E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS25430 e11b73767e60864b45ea55cfbe228362 532 Pfam PF00005 ABC transporter 19 187 1.7E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS25430 e11b73767e60864b45ea55cfbe228362 532 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS25430 e11b73767e60864b45ea55cfbe228362 532 SUPERFAMILY SSF52540 2 79 1.26E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25430 e11b73767e60864b45ea55cfbe228362 532 SUPERFAMILY SSF52540 128 233 1.26E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25430 e11b73767e60864b45ea55cfbe228362 532 Gene3D G3DSA:3.40.50.300 327 516 1.2E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25430 e11b73767e60864b45ea55cfbe228362 532 Gene3D G3DSA:3.40.50.300 5 102 1.7E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25430 e11b73767e60864b45ea55cfbe228362 532 Gene3D G3DSA:3.40.50.300 135 281 1.7E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25430 e11b73767e60864b45ea55cfbe228362 532 Pfam PF12848 ABC transporter 230 303 2.8E-7 T 06-07-2017 IPR032781 ABC-transporter extension domain SMD11_RS25430 e11b73767e60864b45ea55cfbe228362 532 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS02950 676eb7e8ac4ff313676c29082d03b28a 93 SUPERFAMILY SSF50022 28 87 3.27E-12 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS02950 676eb7e8ac4ff313676c29082d03b28a 93 Gene3D G3DSA:2.102.10.10 29 86 5.2E-12 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS02950 676eb7e8ac4ff313676c29082d03b28a 93 Pfam PF00355 Rieske [2Fe-2S] domain 35 82 3.6E-8 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS21720 1e3d6776ba4d13c7080eba365acac4b2 541 Gene3D G3DSA:3.30.379.10 17 182 3.6E-35 T 06-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21720 1e3d6776ba4d13c7080eba365acac4b2 541 Gene3D G3DSA:3.20.20.80 183 533 5.9E-100 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS21720 1e3d6776ba4d13c7080eba365acac4b2 541 SUPERFAMILY SSF51445 185 534 1.09E-104 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS21720 1e3d6776ba4d13c7080eba365acac4b2 541 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 185 504 6.4E-78 T 06-07-2017 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 SMD11_RS21720 1e3d6776ba4d13c7080eba365acac4b2 541 SUPERFAMILY SSF55545 39 184 8.64E-32 T 06-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21720 1e3d6776ba4d13c7080eba365acac4b2 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 267 284 1.6E-44 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21720 1e3d6776ba4d13c7080eba365acac4b2 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 337 350 1.6E-44 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21720 1e3d6776ba4d13c7080eba365acac4b2 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 315 333 1.6E-44 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21720 1e3d6776ba4d13c7080eba365acac4b2 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 208 229 1.6E-44 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21720 1e3d6776ba4d13c7080eba365acac4b2 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 468 484 1.6E-44 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21720 1e3d6776ba4d13c7080eba365acac4b2 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 137 157 1.6E-44 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21720 1e3d6776ba4d13c7080eba365acac4b2 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 179 196 1.6E-44 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21720 1e3d6776ba4d13c7080eba365acac4b2 541 PRINTS PR00738 Glycosyl hydrolase family 20 signature 486 503 1.6E-44 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21720 1e3d6776ba4d13c7080eba365acac4b2 541 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 47 181 2.2E-22 T 06-07-2017 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 SMD11_RS21115 0c33d3780a2fca617199d1a93aae8182 596 Gene3D G3DSA:3.40.50.300 24 179 9.3E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21115 0c33d3780a2fca617199d1a93aae8182 596 SMART SM00487 22 198 1.4E-15 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS21115 0c33d3780a2fca617199d1a93aae8182 596 SUPERFAMILY SSF52540 20 180 1.15E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21115 0c33d3780a2fca617199d1a93aae8182 596 SUPERFAMILY SSF52540 269 388 5.01E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21115 0c33d3780a2fca617199d1a93aae8182 596 SUPERFAMILY SSF52540 138 210 5.01E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21115 0c33d3780a2fca617199d1a93aae8182 596 Gene3D G3DSA:3.40.50.300 287 391 1.4E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21115 0c33d3780a2fca617199d1a93aae8182 596 Pfam PF04851 Type III restriction enzyme, res subunit 134 176 3.7E-5 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SMD11_RS21115 0c33d3780a2fca617199d1a93aae8182 596 Pfam PF04851 Type III restriction enzyme, res subunit 25 95 3.8E-6 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SMD11_RS16470 8346cf4af37d7393e08d01a13dbac4e0 422 Gene3D G3DSA:1.20.1250.20 28 228 4.5E-15 T 06-07-2017 SMD11_RS16470 8346cf4af37d7393e08d01a13dbac4e0 422 Pfam PF07690 Major Facilitator Superfamily 40 382 1.0E-22 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS16470 8346cf4af37d7393e08d01a13dbac4e0 422 PRINTS PR00783 Major intrinsic protein family signature 334 354 4.5E-5 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS16470 8346cf4af37d7393e08d01a13dbac4e0 422 PRINTS PR00783 Major intrinsic protein family signature 69 88 4.5E-5 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS16470 8346cf4af37d7393e08d01a13dbac4e0 422 PRINTS PR00783 Major intrinsic protein family signature 159 178 4.5E-5 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS16470 8346cf4af37d7393e08d01a13dbac4e0 422 PRINTS PR00783 Major intrinsic protein family signature 307 329 4.5E-5 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS16470 8346cf4af37d7393e08d01a13dbac4e0 422 Gene3D G3DSA:1.20.1250.20 236 411 6.2E-17 T 06-07-2017 SMD11_RS16470 8346cf4af37d7393e08d01a13dbac4e0 422 SUPERFAMILY SSF103473 23 418 5.23E-45 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 298 1.5E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 Gene3D G3DSA:3.50.50.60 8 109 2.8E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 SUPERFAMILY SSF55424 318 405 6.87E-28 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 229 245 9.7E-25 T 06-07-2017 SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 9.7E-25 T 06-07-2017 SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 9.7E-25 T 06-07-2017 SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 9.7E-25 T 06-07-2017 SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 9.7E-25 T 06-07-2017 SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 284 7.0E-11 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 12 34 7.0E-11 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 7.0E-11 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 231 252 7.0E-11 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 7.0E-11 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 Gene3D G3DSA:3.50.50.60 110 309 9.1E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 SUPERFAMILY SSF51905 6 282 2.2E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 Pfam PF14759 Reductase C-terminal 323 405 1.1E-25 T 06-07-2017 IPR028202 Reductase, C-terminal SMD11_RS24405 1482f3f3f212a1953d4125f4b878a170 408 Gene3D G3DSA:3.30.390.30 323 405 1.8E-29 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD11_RS22775 6db3075f4f573bd6f4c0f8aae1ca9b21 428 Pfam PF01595 Domain of unknown function DUF21 8 185 4.1E-32 T 06-07-2017 IPR002550 Domain of unknown function DUF21 SMD11_RS22775 6db3075f4f573bd6f4c0f8aae1ca9b21 428 Gene3D G3DSA:3.30.465.10 330 427 3.8E-21 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS22775 6db3075f4f573bd6f4c0f8aae1ca9b21 428 Pfam PF03471 Transporter associated domain 338 427 7.3E-14 T 06-07-2017 IPR005170 Transporter-associated domain SMD11_RS22775 6db3075f4f573bd6f4c0f8aae1ca9b21 428 SUPERFAMILY SSF56176 334 424 1.25E-11 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS22775 6db3075f4f573bd6f4c0f8aae1ca9b21 428 SUPERFAMILY SSF54631 195 340 2.91E-36 T 06-07-2017 SMD11_RS22775 6db3075f4f573bd6f4c0f8aae1ca9b21 428 Pfam PF00571 CBS domain 273 322 3.7E-7 T 06-07-2017 IPR000644 CBS domain SMD11_RS22775 6db3075f4f573bd6f4c0f8aae1ca9b21 428 Pfam PF00571 CBS domain 200 256 1.3E-7 T 06-07-2017 IPR000644 CBS domain SMD11_RS22775 6db3075f4f573bd6f4c0f8aae1ca9b21 428 SMART SM00116 274 322 0.27 T 06-07-2017 IPR000644 CBS domain SMD11_RS22775 6db3075f4f573bd6f4c0f8aae1ca9b21 428 SMART SM00116 209 258 3.2E-5 T 06-07-2017 IPR000644 CBS domain SMD11_RS22775 6db3075f4f573bd6f4c0f8aae1ca9b21 428 SMART SM01091 337 428 1.2E-13 T 06-07-2017 IPR005170 Transporter-associated domain SMD11_RS22775 6db3075f4f573bd6f4c0f8aae1ca9b21 428 Gene3D G3DSA:3.10.580.10 186 329 3.9E-23 T 06-07-2017 SMD11_RS14365 89d8fcd8a45b595d3c642f4b1d44d197 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 51 7.6E-15 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS14365 89d8fcd8a45b595d3c642f4b1d44d197 341 Gene3D G3DSA:3.40.50.2300 173 339 6.6E-47 T 06-07-2017 SMD11_RS14365 89d8fcd8a45b595d3c642f4b1d44d197 341 SMART SM00354 3 74 6.7E-27 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS14365 89d8fcd8a45b595d3c642f4b1d44d197 341 Gene3D G3DSA:1.10.260.40 4 63 1.6E-23 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS14365 89d8fcd8a45b595d3c642f4b1d44d197 341 SUPERFAMILY SSF53822 64 338 5.5E-60 T 06-07-2017 IPR028082 Periplasmic binding protein-like I SMD11_RS14365 89d8fcd8a45b595d3c642f4b1d44d197 341 Pfam PF13377 Periplasmic binding protein-like domain 171 337 1.4E-28 T 06-07-2017 SMD11_RS14365 89d8fcd8a45b595d3c642f4b1d44d197 341 SUPERFAMILY SSF47413 3 62 1.13E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS14365 89d8fcd8a45b595d3c642f4b1d44d197 341 Gene3D G3DSA:3.40.50.2300 64 172 8.1E-34 T 06-07-2017 SMD11_RS25620 46abd8b2c43a23cb326d65c184141a09 418 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 293 416 1.5E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS25620 46abd8b2c43a23cb326d65c184141a09 418 SUPERFAMILY SSF55874 257 325 5.21E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS25620 46abd8b2c43a23cb326d65c184141a09 418 SUPERFAMILY SSF55874 359 416 5.21E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS25620 46abd8b2c43a23cb326d65c184141a09 418 Gene3D G3DSA:3.30.450.40 11 178 3.0E-29 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS25620 46abd8b2c43a23cb326d65c184141a09 418 Pfam PF13185 GAF domain 24 170 9.8E-19 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS25620 46abd8b2c43a23cb326d65c184141a09 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 8.0E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS25620 46abd8b2c43a23cb326d65c184141a09 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 397 8.0E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS25620 46abd8b2c43a23cb326d65c184141a09 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 374 8.0E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS25620 46abd8b2c43a23cb326d65c184141a09 418 SMART SM00065 24 180 1.5E-20 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS25620 46abd8b2c43a23cb326d65c184141a09 418 Gene3D G3DSA:3.30.565.10 270 416 7.1E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS25620 46abd8b2c43a23cb326d65c184141a09 418 SMART SM00387 291 418 8.8E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS25620 46abd8b2c43a23cb326d65c184141a09 418 Pfam PF07730 Histidine kinase 187 254 1.2E-17 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS25620 46abd8b2c43a23cb326d65c184141a09 418 SUPERFAMILY SSF55781 10 183 1.64E-29 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS12520 2df1a588cd83f8a416a5eace9c7b9487 202 SUPERFAMILY SSF52096 13 198 6.63E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS12520 2df1a588cd83f8a416a5eace9c7b9487 202 Gene3D G3DSA:3.90.226.10 6 196 7.7E-68 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS12520 2df1a588cd83f8a416a5eace9c7b9487 202 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 5 196 36.19 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS12520 2df1a588cd83f8a416a5eace9c7b9487 202 Pfam PF00574 Clp protease 15 195 5.9E-68 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SMD11_RS12520 2df1a588cd83f8a416a5eace9c7b9487 202 PRINTS PR00127 Clp protease catalytic subunit P signature 21 36 2.2E-39 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS12520 2df1a588cd83f8a416a5eace9c7b9487 202 PRINTS PR00127 Clp protease catalytic subunit P signature 171 190 2.2E-39 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS12520 2df1a588cd83f8a416a5eace9c7b9487 202 PRINTS PR00127 Clp protease catalytic subunit P signature 92 109 2.2E-39 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS12520 2df1a588cd83f8a416a5eace9c7b9487 202 PRINTS PR00127 Clp protease catalytic subunit P signature 61 81 2.2E-39 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS12520 2df1a588cd83f8a416a5eace9c7b9487 202 PRINTS PR00127 Clp protease catalytic subunit P signature 113 132 2.2E-39 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS25270 49e49d29d787d6520769a512206d4dfb 619 SUPERFAMILY SSF56219 317 615 2.16E-31 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS25270 49e49d29d787d6520769a512206d4dfb 619 Gene3D G3DSA:3.60.10.10 316 615 3.8E-31 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS25270 49e49d29d787d6520769a512206d4dfb 619 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 319 610 4.4E-14 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS08225 68ed7bccad0d9779f4847e7a5e511822 413 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 284 392 1.8E-12 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMD11_RS08225 68ed7bccad0d9779f4847e7a5e511822 413 Gene3D G3DSA:3.20.20.10 22 258 6.2E-54 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS08225 68ed7bccad0d9779f4847e7a5e511822 413 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 21 276 4.4E-33 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMD11_RS08225 68ed7bccad0d9779f4847e7a5e511822 413 SUPERFAMILY SSF51419 20 279 3.6E-58 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS08225 68ed7bccad0d9779f4847e7a5e511822 413 Gene3D G3DSA:2.40.37.10 259 406 5.9E-34 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS08225 68ed7bccad0d9779f4847e7a5e511822 413 SUPERFAMILY SSF50621 249 397 9.84E-36 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS28670 77dd06d8f879e3c817ce16f2f4f6564d 526 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 51 141 3.4E-16 T 06-07-2017 IPR032093 Phospholipase D, N-terminal SMD11_RS28670 77dd06d8f879e3c817ce16f2f4f6564d 526 Pfam PF09423 PhoD-like phosphatase 158 477 1.4E-77 T 06-07-2017 IPR018946 Alkaline phosphatase D-related SMD11_RS28670 77dd06d8f879e3c817ce16f2f4f6564d 526 SUPERFAMILY SSF56300 146 519 2.03E-39 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS28670 77dd06d8f879e3c817ce16f2f4f6564d 526 Gene3D G3DSA:3.60.21.10 145 195 2.4E-35 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS28670 77dd06d8f879e3c817ce16f2f4f6564d 526 Gene3D G3DSA:3.60.21.10 230 523 2.4E-35 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS34560 2b32da82aadb143cc3d4bed3f156a1ed 106 SUPERFAMILY SSF50118 5 104 2.18E-8 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SMD11_RS34560 2b32da82aadb143cc3d4bed3f156a1ed 106 Gene3D G3DSA:2.30.30.110 6 103 9.0E-7 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SMD11_RS34560 2b32da82aadb143cc3d4bed3f156a1ed 106 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 6 102 8.5E-7 T 06-07-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 SMD11_RS32370 00c7115620cbaec672eb9682f136c1f4 459 Gene3D G3DSA:3.40.50.2000 283 436 7.7E-19 T 06-07-2017 SMD11_RS32370 00c7115620cbaec672eb9682f136c1f4 459 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 89 439 1.8E-30 T 06-07-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 SMD11_RS32370 00c7115620cbaec672eb9682f136c1f4 459 Gene3D G3DSA:3.40.50.2000 8 163 2.8E-17 T 06-07-2017 SMD11_RS32370 00c7115620cbaec672eb9682f136c1f4 459 Gene3D G3DSA:3.40.50.2000 195 282 2.8E-17 T 06-07-2017 SMD11_RS32370 00c7115620cbaec672eb9682f136c1f4 459 SUPERFAMILY SSF53756 8 452 5.83E-69 T 06-07-2017 SMD11_RS21320 a87cc4588903aae5bd435d265e02ab17 767 Gene3D G3DSA:1.10.3810.10 98 273 1.5E-64 T 06-07-2017 SMD11_RS21320 a87cc4588903aae5bd435d265e02ab17 767 SUPERFAMILY SSF53955 88 286 3.37E-62 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS21320 a87cc4588903aae5bd435d265e02ab17 767 Pfam PF00912 Transglycosylase 103 272 3.4E-58 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 SMD11_RS21320 a87cc4588903aae5bd435d265e02ab17 767 Pfam PF00905 Penicillin binding protein transpeptidase domain 374 629 8.3E-30 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD11_RS21320 a87cc4588903aae5bd435d265e02ab17 767 SUPERFAMILY SSF56601 305 697 1.06E-84 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS21320 a87cc4588903aae5bd435d265e02ab17 767 SUPERFAMILY SSF56601 257 276 1.06E-84 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS21320 a87cc4588903aae5bd435d265e02ab17 767 Gene3D G3DSA:3.40.710.10 274 708 2.5E-100 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS10830 f658bdda7d366149297b6a9e68e0c182 462 Gene3D G3DSA:3.90.1150.10 311 443 5.3E-29 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS10830 f658bdda7d366149297b6a9e68e0c182 462 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 34 444 43.994 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMD11_RS10830 f658bdda7d366149297b6a9e68e0c182 462 Pfam PF00464 Serine hydroxymethyltransferase 37 405 2.3E-128 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMD11_RS10830 f658bdda7d366149297b6a9e68e0c182 462 PIRSF PIRSF000412 13 443 2.3E-140 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SMD11_RS10830 f658bdda7d366149297b6a9e68e0c182 462 SUPERFAMILY SSF53383 33 444 3.74E-140 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS10830 f658bdda7d366149297b6a9e68e0c182 462 Gene3D G3DSA:3.40.640.10 64 310 4.4E-90 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS13305 89e73c37a2e0fd2ec5d30d5e82eac819 371 Gene3D G3DSA:3.40.50.1820 104 369 2.6E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS13305 89e73c37a2e0fd2ec5d30d5e82eac819 371 Pfam PF00756 Putative esterase 133 279 3.1E-11 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 SMD11_RS13305 89e73c37a2e0fd2ec5d30d5e82eac819 371 SUPERFAMILY SSF53474 107 368 1.21E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12675 0167f2174b9a70dc92328af80f6970b9 327 SMART SM01133 67 308 2.3E-73 T 06-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 SMD11_RS12675 0167f2174b9a70dc92328af80f6970b9 327 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 70 289 3.1E-56 T 06-07-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 SMD11_RS12675 0167f2174b9a70dc92328af80f6970b9 327 SUPERFAMILY SSF51569 68 307 1.15E-73 T 06-07-2017 SMD11_RS12675 0167f2174b9a70dc92328af80f6970b9 327 Pfam PF01791 DeoC/LacD family aldolase 63 305 3.0E-27 T 06-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 SMD11_RS12675 0167f2174b9a70dc92328af80f6970b9 327 Gene3D G3DSA:3.20.20.70 61 319 2.0E-93 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS22185 8f6c498ceee420816ee77d8504f59555 342 Gene3D G3DSA:3.40.50.720 1 138 2.2E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS22185 8f6c498ceee420816ee77d8504f59555 342 PIRSF PIRSF000148 1 341 1.5E-108 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD11_RS22185 8f6c498ceee420816ee77d8504f59555 342 SUPERFAMILY SSF51735 2 153 1.36E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS22185 8f6c498ceee420816ee77d8504f59555 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 115 4.3E-30 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD11_RS22185 8f6c498ceee420816ee77d8504f59555 342 SMART SM00859 2 117 3.8E-40 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SMD11_RS22185 8f6c498ceee420816ee77d8504f59555 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 136 323 1.7E-51 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS22185 8f6c498ceee420816ee77d8504f59555 342 Gene3D G3DSA:3.30.360.10 139 319 6.2E-67 T 06-07-2017 SMD11_RS22185 8f6c498ceee420816ee77d8504f59555 342 SUPERFAMILY SSF55347 126 324 8.98E-59 T 06-07-2017 SMD11_RS22185 8f6c498ceee420816ee77d8504f59555 342 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 2 337 3.5E-126 T 06-07-2017 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD11_RS22185 8f6c498ceee420816ee77d8504f59555 342 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 337 33.101 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD11_RS22185 8f6c498ceee420816ee77d8504f59555 342 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 240 254 - T 06-07-2017 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SMD11_RS15790 7e661d9cb4917c478f4fd0e451264895 205 SUPERFAMILY SSF47413 25 90 2.06E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS15790 7e661d9cb4917c478f4fd0e451264895 205 Pfam PF01381 Helix-turn-helix 34 87 2.0E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS15790 7e661d9cb4917c478f4fd0e451264895 205 Gene3D G3DSA:1.10.260.40 30 129 1.4E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS15790 7e661d9cb4917c478f4fd0e451264895 205 SUPERFAMILY SSF51182 72 201 1.22E-21 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS15790 7e661d9cb4917c478f4fd0e451264895 205 Pfam PF07883 Cupin domain 132 199 1.4E-10 T 06-07-2017 IPR013096 Cupin 2, conserved barrel SMD11_RS15790 7e661d9cb4917c478f4fd0e451264895 205 Gene3D G3DSA:2.60.120.10 130 204 1.1E-23 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS15790 7e661d9cb4917c478f4fd0e451264895 205 SMART SM00530 32 87 4.0E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS19825 bf89ddb41bb5a8012a12db99a5a8e3aa 106 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 6.8E-19 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMD11_RS19825 bf89ddb41bb5a8012a12db99a5a8e3aa 106 Pfam PF09723 Zinc ribbon domain 2 40 6.2E-13 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMD11_RS19825 bf89ddb41bb5a8012a12db99a5a8e3aa 106 SMART SM00834 2 41 3.7E-13 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMD11_RS15355 d36407ea28e3ade634ba8cf4aeaeee34 330 SUPERFAMILY SSF52540 86 245 3.42E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15355 d36407ea28e3ade634ba8cf4aeaeee34 330 SUPERFAMILY SSF52540 1 51 3.42E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15355 d36407ea28e3ade634ba8cf4aeaeee34 330 Gene3D G3DSA:3.40.50.300 1 251 6.8E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15355 d36407ea28e3ade634ba8cf4aeaeee34 330 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 222 3.0E-11 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain SMD11_RS10560 a2fb7976ed756ad5e757e42b3f1d9e2a 692 Pfam PF01515 Phosphate acetyl/butaryl transferase 366 683 8.9E-128 T 06-07-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SMD11_RS10560 a2fb7976ed756ad5e757e42b3f1d9e2a 692 Gene3D G3DSA:3.40.50.300 3 204 4.5E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10560 a2fb7976ed756ad5e757e42b3f1d9e2a 692 Pfam PF07085 DRTGG domain 209 319 3.3E-22 T 06-07-2017 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SMD11_RS10560 a2fb7976ed756ad5e757e42b3f1d9e2a 692 SUPERFAMILY SSF52540 4 215 2.18E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10560 a2fb7976ed756ad5e757e42b3f1d9e2a 692 Gene3D G3DSA:3.40.50.10750 501 659 4.8E-67 T 06-07-2017 SMD11_RS10560 a2fb7976ed756ad5e757e42b3f1d9e2a 692 SUPERFAMILY SSF75138 204 321 3.26E-19 T 06-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SMD11_RS10560 a2fb7976ed756ad5e757e42b3f1d9e2a 692 Pfam PF13500 AAA domain 3 206 1.1E-19 T 06-07-2017 SMD11_RS10560 a2fb7976ed756ad5e757e42b3f1d9e2a 692 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 382 683 8.8E-124 T 06-07-2017 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SMD11_RS10560 a2fb7976ed756ad5e757e42b3f1d9e2a 692 Gene3D G3DSA:3.40.1390.20 205 342 2.2E-26 T 06-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SMD11_RS10560 a2fb7976ed756ad5e757e42b3f1d9e2a 692 SUPERFAMILY SSF53659 365 686 1.19E-96 T 06-07-2017 SMD11_RS26610 7bffca44333e6f4ace7e204631eb58d7 307 Gene3D G3DSA:3.40.50.1010 1 181 2.0E-47 T 06-07-2017 IPR029060 PIN domain-like SMD11_RS26610 7bffca44333e6f4ace7e204631eb58d7 307 SMART SM00279 186 221 1.3E-10 T 06-07-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 SMD11_RS26610 7bffca44333e6f4ace7e204631eb58d7 307 SUPERFAMILY SSF88723 1 166 1.06E-37 T 06-07-2017 IPR029060 PIN domain-like SMD11_RS26610 7bffca44333e6f4ace7e204631eb58d7 307 SUPERFAMILY SSF47807 189 297 8.22E-19 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SMD11_RS26610 7bffca44333e6f4ace7e204631eb58d7 307 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 188 269 3.7E-17 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SMD11_RS26610 7bffca44333e6f4ace7e204631eb58d7 307 Gene3D G3DSA:1.10.150.20 182 234 1.4E-18 T 06-07-2017 SMD11_RS26610 7bffca44333e6f4ace7e204631eb58d7 307 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 1 183 2.9E-47 T 06-07-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 SMD11_RS26610 7bffca44333e6f4ace7e204631eb58d7 307 SMART SM00475 1 277 3.0E-77 T 06-07-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 SMD11_RS13420 178f6b4726c7d529616878f4caf8de52 336 Gene3D G3DSA:3.40.50.880 22 234 1.2E-40 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS13420 178f6b4726c7d529616878f4caf8de52 336 Pfam PF01965 DJ-1/PfpI family 84 189 2.1E-10 T 06-07-2017 IPR002818 DJ-1/PfpI SMD11_RS13420 178f6b4726c7d529616878f4caf8de52 336 SMART SM00342 245 328 3.0E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS13420 178f6b4726c7d529616878f4caf8de52 336 SUPERFAMILY SSF52317 21 211 1.7E-40 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS13420 178f6b4726c7d529616878f4caf8de52 336 SUPERFAMILY SSF46689 230 278 3.76E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS13420 178f6b4726c7d529616878f4caf8de52 336 Pfam PF12833 Helix-turn-helix domain 251 330 3.6E-16 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS13420 178f6b4726c7d529616878f4caf8de52 336 Gene3D G3DSA:1.10.10.60 235 282 1.3E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS13420 178f6b4726c7d529616878f4caf8de52 336 Gene3D G3DSA:1.10.10.60 283 330 1.8E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS10285 3a6fa5965fa4c5a759313a78c4d8233e 374 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 6 372 2.7E-107 T 06-07-2017 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 SMD11_RS10285 3a6fa5965fa4c5a759313a78c4d8233e 374 Gene3D G3DSA:2.40.30.110 291 366 1.5E-27 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMD11_RS10285 3a6fa5965fa4c5a759313a78c4d8233e 374 SUPERFAMILY SSF101790 292 373 6.54E-24 T 06-07-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain SMD11_RS10285 3a6fa5965fa4c5a759313a78c4d8233e 374 Pfam PF01571 Aminomethyltransferase folate-binding domain 11 260 4.7E-90 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal SMD11_RS10285 3a6fa5965fa4c5a759313a78c4d8233e 374 Hamap MF_00259 Aminomethyltransferase [gcvT]. 4 372 44.015 T 06-07-2017 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMD11_RS10285 3a6fa5965fa4c5a759313a78c4d8233e 374 Gene3D G3DSA:3.30.1360.120 6 55 1.1E-52 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 SMD11_RS10285 3a6fa5965fa4c5a759313a78c4d8233e 374 Gene3D G3DSA:3.30.1360.120 144 238 1.1E-52 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 SMD11_RS10285 3a6fa5965fa4c5a759313a78c4d8233e 374 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 271 366 1.0E-22 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMD11_RS10285 3a6fa5965fa4c5a759313a78c4d8233e 374 SUPERFAMILY SSF103025 6 283 8.16E-94 T 06-07-2017 SMD11_RS10285 3a6fa5965fa4c5a759313a78c4d8233e 374 PIRSF PIRSF006487 1 374 1.6E-95 T 06-07-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 SMD11_RS10285 3a6fa5965fa4c5a759313a78c4d8233e 374 Gene3D G3DSA:3.30.70.1400 56 140 3.1E-26 T 06-07-2017 SMD11_RS04095 2215461342306c477d1795561353085d 217 SUPERFAMILY SSF53335 2 176 1.18E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS04095 2215461342306c477d1795561353085d 217 Pfam PF05175 Methyltransferase small domain 3 105 8.4E-15 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 SMD11_RS04095 2215461342306c477d1795561353085d 217 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 9 186 1.1E-36 T 06-07-2017 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 SMD11_RS04095 2215461342306c477d1795561353085d 217 Gene3D G3DSA:3.40.50.150 2 177 1.1E-41 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS04095 2215461342306c477d1795561353085d 217 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 98 104 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMD11_RS24155 577324d0e03fc88c50a4914b28d7254d 237 Gene3D G3DSA:1.10.10.10 172 231 9.8E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS24155 577324d0e03fc88c50a4914b28d7254d 237 SUPERFAMILY SSF46894 166 232 2.24E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS24155 577324d0e03fc88c50a4914b28d7254d 237 SUPERFAMILY SSF52172 8 136 4.7E-34 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS24155 577324d0e03fc88c50a4914b28d7254d 237 Pfam PF00196 Bacterial regulatory proteins, luxR family 171 226 1.9E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24155 577324d0e03fc88c50a4914b28d7254d 237 Pfam PF00072 Response regulator receiver domain 14 128 6.6E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS24155 577324d0e03fc88c50a4914b28d7254d 237 SMART SM00448 12 127 8.5E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS24155 577324d0e03fc88c50a4914b28d7254d 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 202 6.1E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24155 577324d0e03fc88c50a4914b28d7254d 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 202 214 6.1E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24155 577324d0e03fc88c50a4914b28d7254d 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 186 6.1E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24155 577324d0e03fc88c50a4914b28d7254d 237 ProSitePatterns PS00622 LuxR-type HTH domain signature. 186 213 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24155 577324d0e03fc88c50a4914b28d7254d 237 Gene3D G3DSA:3.40.50.2300 10 171 4.0E-39 T 06-07-2017 SMD11_RS24155 577324d0e03fc88c50a4914b28d7254d 237 SMART SM00421 169 226 3.6E-25 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS29635 8bb8451a1519d0a6af0231f436d182ca 110 SUPERFAMILY SSF54909 1 95 7.58E-28 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS29635 8bb8451a1519d0a6af0231f436d182ca 110 Gene3D G3DSA:3.30.70.900 1 91 7.8E-25 T 06-07-2017 SMD11_RS29635 8bb8451a1519d0a6af0231f436d182ca 110 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 9.8E-19 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain SMD11_RS11190 8eda1ea9a2bce06991924b16995e6771 312 Gene3D G3DSA:3.40.47.10 2 160 2.3E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS11190 8eda1ea9a2bce06991924b16995e6771 312 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 311 60.518 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS11190 8eda1ea9a2bce06991924b16995e6771 312 Gene3D G3DSA:3.40.47.10 161 311 8.4E-41 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS11190 8eda1ea9a2bce06991924b16995e6771 312 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 310 3.8E-91 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS11190 8eda1ea9a2bce06991924b16995e6771 312 SUPERFAMILY SSF53901 4 311 7.41E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS11190 8eda1ea9a2bce06991924b16995e6771 312 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 222 310 1.7E-26 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS11190 8eda1ea9a2bce06991924b16995e6771 312 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 181 5.3E-27 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS17435 c2b33134bb11ae3a9eaec4193405d834 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS17435 c2b33134bb11ae3a9eaec4193405d834 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 102 122 7.6E-52 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS17435 c2b33134bb11ae3a9eaec4193405d834 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 82 99 7.6E-52 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS17435 c2b33134bb11ae3a9eaec4193405d834 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 207 226 7.6E-52 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS17435 c2b33134bb11ae3a9eaec4193405d834 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 167 190 7.6E-52 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS17435 c2b33134bb11ae3a9eaec4193405d834 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 10 27 7.6E-52 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS17435 c2b33134bb11ae3a9eaec4193405d834 257 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 233 252 7.6E-52 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS17435 c2b33134bb11ae3a9eaec4193405d834 257 Pfam PF00106 short chain dehydrogenase 4 195 3.0E-56 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17435 c2b33134bb11ae3a9eaec4193405d834 257 SUPERFAMILY SSF51735 2 253 4.87E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17435 c2b33134bb11ae3a9eaec4193405d834 257 Gene3D G3DSA:3.40.50.720 1 253 6.1E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17435 c2b33134bb11ae3a9eaec4193405d834 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17435 c2b33134bb11ae3a9eaec4193405d834 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17435 c2b33134bb11ae3a9eaec4193405d834 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17435 c2b33134bb11ae3a9eaec4193405d834 257 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 6 256 2.0E-102 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 Gene3D G3DSA:3.30.1360.70 6 107 7.7E-27 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 Gene3D G3DSA:1.10.730.10 463 584 1.8E-33 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 SUPERFAMILY SSF52374 112 461 3.6E-84 T 06-07-2017 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 Gene3D G3DSA:3.40.50.620 113 461 1.5E-101 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 13 584 2.4E-134 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 89 3.9E-17 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 SUPERFAMILY SSF47323 463 584 3.66E-32 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 584 25.841 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 SMART SM01016 9 89 1.0E-25 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 Pfam PF05746 DALR anticodon binding domain 469 584 4.5E-32 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 SUPERFAMILY SSF55190 7 98 1.57E-17 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 SMART SM00836 469 584 4.8E-38 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 125 136 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 PRINTS PR01038 Arginyl-tRNA synthetase signature 312 333 4.2E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 PRINTS PR01038 Arginyl-tRNA synthetase signature 156 169 4.2E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 PRINTS PR01038 Arginyl-tRNA synthetase signature 132 148 4.2E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 PRINTS PR01038 Arginyl-tRNA synthetase signature 117 132 4.2E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMD11_RS18305 2210da4f93795ce622187abaf14123b8 584 Pfam PF00750 tRNA synthetases class I (R) 111 454 6.4E-103 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SMD11_RS32680 5096f99465568601a586c2aa25279296 323 Gene3D G3DSA:3.40.50.880 5 195 8.0E-35 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS32680 5096f99465568601a586c2aa25279296 323 Gene3D G3DSA:1.10.10.60 271 318 1.2E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS32680 5096f99465568601a586c2aa25279296 323 SMART SM00342 232 315 3.6E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS32680 5096f99465568601a586c2aa25279296 323 Pfam PF01965 DJ-1/PfpI family 37 177 4.1E-13 T 06-07-2017 IPR002818 DJ-1/PfpI SMD11_RS32680 5096f99465568601a586c2aa25279296 323 Pfam PF12833 Helix-turn-helix domain 239 316 1.9E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS32680 5096f99465568601a586c2aa25279296 323 SUPERFAMILY SSF52317 5 195 4.06E-35 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS32680 5096f99465568601a586c2aa25279296 323 Gene3D G3DSA:1.10.10.60 212 270 2.8E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS32680 5096f99465568601a586c2aa25279296 323 SUPERFAMILY SSF46689 269 319 3.63E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS32680 5096f99465568601a586c2aa25279296 323 SUPERFAMILY SSF46689 217 266 3.94E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS27435 8c200682f4eab9311adee5b52b38481b 495 SMART SM00116 113 161 0.0035 T 06-07-2017 IPR000644 CBS domain SMD11_RS27435 8c200682f4eab9311adee5b52b38481b 495 SMART SM00116 172 220 9.8 T 06-07-2017 IPR000644 CBS domain SMD11_RS27435 8c200682f4eab9311adee5b52b38481b 495 Gene3D G3DSA:3.20.20.70 24 490 1.5E-134 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS27435 8c200682f4eab9311adee5b52b38481b 495 PIRSF PIRSF000130 16 495 1.6E-146 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SMD11_RS27435 8c200682f4eab9311adee5b52b38481b 495 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 17 492 3.0E-279 T 06-07-2017 IPR005991 IMP dehydrogenase-related 1 SMD11_RS27435 8c200682f4eab9311adee5b52b38481b 495 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 28 489 5.5E-101 T 06-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 SMD11_RS27435 8c200682f4eab9311adee5b52b38481b 495 SMART SM01240 26 490 8.0E-193 T 06-07-2017 SMD11_RS27435 8c200682f4eab9311adee5b52b38481b 495 SUPERFAMILY SSF51412 28 108 7.98E-91 T 06-07-2017 SMD11_RS27435 8c200682f4eab9311adee5b52b38481b 495 SUPERFAMILY SSF51412 230 489 7.98E-91 T 06-07-2017 SMD11_RS27435 8c200682f4eab9311adee5b52b38481b 495 SUPERFAMILY SSF54631 112 219 4.42E-20 T 06-07-2017 SMD11_RS27435 8c200682f4eab9311adee5b52b38481b 495 Pfam PF00571 CBS domain 166 218 4.8E-5 T 06-07-2017 IPR000644 CBS domain SMD11_RS27435 8c200682f4eab9311adee5b52b38481b 495 Pfam PF00571 CBS domain 114 157 6.4E-7 T 06-07-2017 IPR000644 CBS domain SMD11_RS15115 bf554e5a5fb18b60861a771ab738bc03 300 Gene3D G3DSA:3.40.190.10 181 266 5.0E-13 T 06-07-2017 SMD11_RS15115 bf554e5a5fb18b60861a771ab738bc03 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS15115 bf554e5a5fb18b60861a771ab738bc03 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS15115 bf554e5a5fb18b60861a771ab738bc03 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS15115 bf554e5a5fb18b60861a771ab738bc03 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.1E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS15115 bf554e5a5fb18b60861a771ab738bc03 300 Pfam PF03466 LysR substrate binding domain 88 297 7.5E-30 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS15115 bf554e5a5fb18b60861a771ab738bc03 300 SUPERFAMILY SSF46785 2 86 3.4E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15115 bf554e5a5fb18b60861a771ab738bc03 300 SUPERFAMILY SSF53850 90 299 6.37E-32 T 06-07-2017 SMD11_RS15115 bf554e5a5fb18b60861a771ab738bc03 300 Gene3D G3DSA:1.10.10.10 2 77 1.6E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15115 bf554e5a5fb18b60861a771ab738bc03 300 Gene3D G3DSA:3.40.190.10 89 180 2.0E-14 T 06-07-2017 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 Gene3D G3DSA:3.50.50.60 144 336 5.1E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 Gene3D G3DSA:3.30.390.30 347 466 8.1E-27 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 327 1.8E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 2.9E-34 T 06-07-2017 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 2.9E-34 T 06-07-2017 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 2.9E-34 T 06-07-2017 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 2.9E-34 T 06-07-2017 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 2.9E-34 T 06-07-2017 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 15 465 1.9E-136 T 06-07-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 SUPERFAMILY SSF51905 12 372 1.99E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 49 59 - T 06-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 SUPERFAMILY SSF55424 344 465 1.89E-28 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 455 1.6E-22 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 Gene3D G3DSA:3.50.50.60 15 143 1.2E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 PIRSF PIRSF000350 2 452 7.3E-70 T 06-07-2017 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 1.3E-63 T 06-07-2017 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 1.3E-63 T 06-07-2017 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 1.3E-63 T 06-07-2017 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 16 38 1.3E-63 T 06-07-2017 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 1.3E-63 T 06-07-2017 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 1.3E-63 T 06-07-2017 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 1.3E-63 T 06-07-2017 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 48 63 1.3E-63 T 06-07-2017 SMD11_RS24080 47d93ecba507564ca329b9c6c9489a1d 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 1.3E-63 T 06-07-2017 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 SUPERFAMILY SSF48452 821 960 1.3E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 PRINTS PR00364 Disease resistance protein signature 386 400 1.9E-8 T 06-07-2017 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 PRINTS PR00364 Disease resistance protein signature 309 324 1.9E-8 T 06-07-2017 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 PRINTS PR00364 Disease resistance protein signature 471 485 1.9E-8 T 06-07-2017 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 Gene3D G3DSA:3.40.50.300 308 403 4.2E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 SUPERFAMILY SSF48452 101 263 4.23E-35 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 SMART SM00862 24 99 3.9E-7 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 SUPERFAMILY SSF46894 12 88 9.07E-12 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 SUPERFAMILY SSF52540 276 537 3.63E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 Pfam PF13424 Tetratricopeptide repeat 778 838 1.1E-7 T 06-07-2017 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 Pfam PF13424 Tetratricopeptide repeat 845 916 3.7E-9 T 06-07-2017 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 Pfam PF00931 NB-ARC domain 292 490 1.8E-14 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 SUPERFAMILY SSF48452 702 841 3.59E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 SMART SM00028 806 839 57.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 SMART SM00028 925 958 7.5 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 SMART SM00028 886 919 79.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 SMART SM00028 726 759 71.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 SMART SM00028 846 879 0.02 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 Gene3D G3DSA:1.10.10.10 32 100 6.6E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 SMART SM01043 106 250 1.1E-51 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 Gene3D G3DSA:1.25.40.10 720 762 7.9E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 Gene3D G3DSA:1.25.40.10 767 957 2.9E-23 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 Gene3D G3DSA:1.25.40.10 109 243 7.9E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 Gene3D G3DSA:1.25.40.10 588 619 7.9E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 Pfam PF00486 Transcriptional regulatory protein, C terminal 32 87 1.3E-7 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS19445 1ebc5491f3e5d8432aa35e12842257e1 977 Pfam PF03704 Bacterial transcriptional activator domain 106 250 4.6E-44 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS09280 ce36e38ef0880b76b630e78324cd2957 179 Pfam PF00583 Acetyltransferase (GNAT) family 58 151 3.9E-9 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS09280 ce36e38ef0880b76b630e78324cd2957 179 Gene3D G3DSA:3.40.630.30 13 155 7.0E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS09280 ce36e38ef0880b76b630e78324cd2957 179 SUPERFAMILY SSF55729 13 170 3.38E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS03235 7a6a05bf186cabbd11c04f07db82094b 242 Pfam PF01553 Acyltransferase 24 149 2.1E-28 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD11_RS03235 7a6a05bf186cabbd11c04f07db82094b 242 SUPERFAMILY SSF69593 20 205 1.7E-37 T 06-07-2017 SMD11_RS03235 7a6a05bf186cabbd11c04f07db82094b 242 SMART SM00563 38 152 1.7E-35 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD11_RS03235 7a6a05bf186cabbd11c04f07db82094b 242 Gene3D G3DSA:3.40.1130.10 29 207 2.1E-24 T 06-07-2017 SMD11_RS14550 b897f0733f5a0f26d7e44b1967940465 376 SUPERFAMILY SSF53850 58 375 8.03E-86 T 06-07-2017 SMD11_RS14550 b897f0733f5a0f26d7e44b1967940465 376 PIRSF PIRSF002756 10 376 7.3E-115 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 SMD11_RS14550 b897f0733f5a0f26d7e44b1967940465 376 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 60 374 3.7E-78 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 SMD11_RS14550 b897f0733f5a0f26d7e44b1967940465 376 Gene3D G3DSA:3.40.190.10 56 211 1.9E-43 T 06-07-2017 SMD11_RS14550 b897f0733f5a0f26d7e44b1967940465 376 Gene3D G3DSA:3.40.190.10 238 372 9.3E-17 T 06-07-2017 SMD11_RS14550 b897f0733f5a0f26d7e44b1967940465 376 Pfam PF12849 PBP superfamily domain 55 346 3.2E-57 T 06-07-2017 IPR024370 PBP domain SMD11_RS11995 76014c769c581703590dacbcf8431035 333 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 56 96 6.0E-11 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD11_RS11995 76014c769c581703590dacbcf8431035 333 Gene3D G3DSA:1.10.3720.10 125 330 3.4E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11995 76014c769c581703590dacbcf8431035 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 149 333 4.7E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11995 76014c769c581703590dacbcf8431035 333 SUPERFAMILY SSF161098 128 318 9.03E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS04660 ca16448451c2a6cde205eb6921086bf9 340 Gene3D G3DSA:3.30.70.260 241 332 9.7E-14 T 06-07-2017 SMD11_RS04660 ca16448451c2a6cde205eb6921086bf9 340 SUPERFAMILY SSF55021 261 332 2.75E-10 T 06-07-2017 SMD11_RS04660 ca16448451c2a6cde205eb6921086bf9 340 SUPERFAMILY SSF52540 1 244 1.01E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04660 ca16448451c2a6cde205eb6921086bf9 340 SMART SM00930 266 340 1.7E-7 T 06-07-2017 IPR018449 NIL domain SMD11_RS04660 ca16448451c2a6cde205eb6921086bf9 340 SMART SM00382 34 222 2.6E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS04660 ca16448451c2a6cde205eb6921086bf9 340 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS04660 ca16448451c2a6cde205eb6921086bf9 340 Pfam PF09383 NIL domain 269 330 4.4E-9 T 06-07-2017 IPR018449 NIL domain SMD11_RS04660 ca16448451c2a6cde205eb6921086bf9 340 Pfam PF00005 ABC transporter 26 173 7.6E-37 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS04660 ca16448451c2a6cde205eb6921086bf9 340 Gene3D G3DSA:3.40.50.300 1 240 2.3E-90 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04070 f6b4cd4937b8e9251dbb52cfd4fcd947 369 Gene3D G3DSA:3.40.50.1820 96 362 1.0E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04070 f6b4cd4937b8e9251dbb52cfd4fcd947 369 Pfam PF00756 Putative esterase 121 347 2.2E-15 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 SMD11_RS04070 f6b4cd4937b8e9251dbb52cfd4fcd947 369 SUPERFAMILY SSF53474 110 347 3.7E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS13585 97dd209ed8861efbf6d868a54284f20b 251 SUPERFAMILY SSF53697 8 207 2.18E-23 T 06-07-2017 SMD11_RS13585 97dd209ed8861efbf6d868a54284f20b 251 Hamap MF_01240 UPF0309 protein . 6 250 38.748 T 06-07-2017 IPR022951 Uncharacterised protein family UPF0309 SMD11_RS13585 97dd209ed8861efbf6d868a54284f20b 251 Pfam PF13580 SIS domain 9 146 7.0E-40 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 SMD11_RS13585 97dd209ed8861efbf6d868a54284f20b 251 Gene3D G3DSA:3.40.50.10490 6 246 2.7E-70 T 06-07-2017 SMD11_RS08005 8765408c70fc83d0fa9765064797c93b 552 SUPERFAMILY SSF52540 9 248 2.99E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08005 8765408c70fc83d0fa9765064797c93b 552 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS08005 8765408c70fc83d0fa9765064797c93b 552 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS08005 8765408c70fc83d0fa9765064797c93b 552 SUPERFAMILY SSF52540 376 549 5.33E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08005 8765408c70fc83d0fa9765064797c93b 552 Pfam PF12848 ABC transporter 237 285 6.8E-5 T 06-07-2017 IPR032781 ABC-transporter extension domain SMD11_RS08005 8765408c70fc83d0fa9765064797c93b 552 SMART SM00382 30 243 4.7E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS08005 8765408c70fc83d0fa9765064797c93b 552 SMART SM00382 381 544 2.6E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS08005 8765408c70fc83d0fa9765064797c93b 552 Gene3D G3DSA:3.40.50.300 8 104 2.6E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08005 8765408c70fc83d0fa9765064797c93b 552 Gene3D G3DSA:3.40.50.300 376 549 4.3E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08005 8765408c70fc83d0fa9765064797c93b 552 Gene3D G3DSA:3.40.50.300 146 279 2.6E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08005 8765408c70fc83d0fa9765064797c93b 552 Pfam PF00005 ABC transporter 376 500 4.6E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS08005 8765408c70fc83d0fa9765064797c93b 552 Pfam PF00005 ABC transporter 21 198 6.4E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS24985 1f162d16639b9160c0f0ec037fee7213 199 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 187 7.6E-47 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 SMD11_RS24985 1f162d16639b9160c0f0ec037fee7213 199 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 26.935 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 SMD11_RS24985 1f162d16639b9160c0f0ec037fee7213 199 SUPERFAMILY SSF52540 3 194 2.06E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24985 1f162d16639b9160c0f0ec037fee7213 199 Pfam PF01121 Dephospho-CoA kinase 3 180 3.8E-55 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 SMD11_RS24985 1f162d16639b9160c0f0ec037fee7213 199 Gene3D G3DSA:3.40.50.300 1 196 1.8E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23675 1c30e8e856c81fbcc7d2d3d2c1fee659 371 Pfam PF01032 FecCD transport family 45 362 1.1E-93 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD11_RS23675 1c30e8e856c81fbcc7d2d3d2c1fee659 371 Gene3D G3DSA:1.10.3470.10 30 366 9.2E-110 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS23675 1c30e8e856c81fbcc7d2d3d2c1fee659 371 SUPERFAMILY SSF81345 28 362 2.35E-84 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS10745 5a71e35bf80e0a30fe72493ee5c408ac 282 Gene3D G3DSA:1.10.1040.10 188 281 1.1E-29 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS10745 5a71e35bf80e0a30fe72493ee5c408ac 282 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 183 8.4E-69 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS10745 5a71e35bf80e0a30fe72493ee5c408ac 282 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 06-07-2017 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS10745 5a71e35bf80e0a30fe72493ee5c408ac 282 PIRSF PIRSF000105 1 282 7.1E-91 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 SMD11_RS10745 5a71e35bf80e0a30fe72493ee5c408ac 282 SUPERFAMILY SSF48179 186 281 4.25E-27 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS10745 5a71e35bf80e0a30fe72493ee5c408ac 282 Gene3D G3DSA:3.40.50.720 3 187 8.8E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10745 5a71e35bf80e0a30fe72493ee5c408ac 282 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 281 9.6E-30 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS10745 5a71e35bf80e0a30fe72493ee5c408ac 282 SUPERFAMILY SSF51735 3 182 1.13E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS21750 bd2fcfb5861231c93d6baf521017e366 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 223 5.9E-25 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS21750 bd2fcfb5861231c93d6baf521017e366 385 SUPERFAMILY SSF56645 4 247 1.7E-81 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS21750 bd2fcfb5861231c93d6baf521017e366 385 Gene3D G3DSA:2.40.110.10 123 223 1.5E-37 T 06-07-2017 SMD11_RS21750 bd2fcfb5861231c93d6baf521017e366 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 383 1.6E-39 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS21750 bd2fcfb5861231c93d6baf521017e366 385 Gene3D G3DSA:1.10.540.10 6 120 8.3E-39 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS21750 bd2fcfb5861231c93d6baf521017e366 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 342 361 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD11_RS21750 bd2fcfb5861231c93d6baf521017e366 385 Gene3D G3DSA:1.20.140.10 224 383 1.9E-55 T 06-07-2017 SMD11_RS21750 bd2fcfb5861231c93d6baf521017e366 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 1.1E-36 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS21750 bd2fcfb5861231c93d6baf521017e366 385 SUPERFAMILY SSF47203 233 383 2.9E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS20455 715a61a974f4b1465690759f8768ca07 406 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMD11_RS20455 715a61a974f4b1465690759f8768ca07 406 SUPERFAMILY SSF53901 3 282 9.77E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20455 715a61a974f4b1465690759f8768ca07 406 Pfam PF00108 Thiolase, N-terminal domain 5 274 2.9E-60 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD11_RS20455 715a61a974f4b1465690759f8768ca07 406 PIRSF PIRSF000429 1 406 8.0E-128 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS20455 715a61a974f4b1465690759f8768ca07 406 Gene3D G3DSA:3.40.47.10 4 125 1.5E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20455 715a61a974f4b1465690759f8768ca07 406 Gene3D G3DSA:3.40.47.10 210 288 1.5E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20455 715a61a974f4b1465690759f8768ca07 406 SUPERFAMILY SSF53901 283 404 8.24E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20455 715a61a974f4b1465690759f8768ca07 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 403 3.0E-137 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS20455 715a61a974f4b1465690759f8768ca07 406 Gene3D G3DSA:3.40.47.10 289 404 7.2E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20455 715a61a974f4b1465690759f8768ca07 406 Gene3D G3DSA:3.40.47.10 170 209 7.2E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20455 715a61a974f4b1465690759f8768ca07 406 Pfam PF02803 Thiolase, C-terminal domain 282 404 1.6E-46 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD11_RS20505 5422f6cf3e60770b57c82b037321121e 396 SUPERFAMILY SSF55031 206 315 1.15E-18 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS20505 5422f6cf3e60770b57c82b037321121e 396 Gene3D G3DSA:3.40.630.10 2 216 2.1E-93 T 06-07-2017 SMD11_RS20505 5422f6cf3e60770b57c82b037321121e 396 Gene3D G3DSA:3.40.630.10 336 394 2.1E-93 T 06-07-2017 SMD11_RS20505 5422f6cf3e60770b57c82b037321121e 396 Pfam PF01546 Peptidase family M20/M25/M40 67 391 5.2E-25 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD11_RS20505 5422f6cf3e60770b57c82b037321121e 396 Gene3D G3DSA:3.30.70.360 217 317 2.8E-28 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS20505 5422f6cf3e60770b57c82b037321121e 396 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 11 389 8.2E-85 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 SMD11_RS20505 5422f6cf3e60770b57c82b037321121e 396 SUPERFAMILY SSF53187 321 394 1.37E-72 T 06-07-2017 SMD11_RS20505 5422f6cf3e60770b57c82b037321121e 396 SUPERFAMILY SSF53187 11 213 1.37E-72 T 06-07-2017 SMD11_RS20505 5422f6cf3e60770b57c82b037321121e 396 PIRSF PIRSF001235 1 396 1.7E-123 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 SMD11_RS30210 0f4b138873d57354da69bd9c04a32dd4 330 Pfam PF01965 DJ-1/PfpI family 5 183 1.8E-24 T 06-07-2017 IPR002818 DJ-1/PfpI SMD11_RS30210 0f4b138873d57354da69bd9c04a32dd4 330 SUPERFAMILY SSF46689 276 326 2.96E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS30210 0f4b138873d57354da69bd9c04a32dd4 330 SMART SM00342 239 322 1.2E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS30210 0f4b138873d57354da69bd9c04a32dd4 330 Gene3D G3DSA:1.10.10.60 278 326 1.8E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS30210 0f4b138873d57354da69bd9c04a32dd4 330 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 276 318 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD11_RS30210 0f4b138873d57354da69bd9c04a32dd4 330 Gene3D G3DSA:3.40.50.880 6 229 5.4E-55 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS30210 0f4b138873d57354da69bd9c04a32dd4 330 Pfam PF12833 Helix-turn-helix domain 245 324 2.4E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS30210 0f4b138873d57354da69bd9c04a32dd4 330 SUPERFAMILY SSF46689 225 272 1.94E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS30210 0f4b138873d57354da69bd9c04a32dd4 330 Gene3D G3DSA:1.10.10.60 230 277 8.3E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS30210 0f4b138873d57354da69bd9c04a32dd4 330 SUPERFAMILY SSF52317 5 203 4.98E-48 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS27195 c25eace948eb695fb7d97203b25ab93e 161 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 4 82 2.3E-15 T 06-07-2017 IPR003849 Preprotein translocase YajC SMD11_RS27195 c25eace948eb695fb7d97203b25ab93e 161 Pfam PF02699 Preprotein translocase subunit 4 79 8.8E-17 T 06-07-2017 IPR003849 Preprotein translocase YajC SMD11_RS27195 c25eace948eb695fb7d97203b25ab93e 161 SMART SM01323 1 82 5.6E-22 T 06-07-2017 IPR003849 Preprotein translocase YajC SMD11_RS03550 247d5f0daaf31cd9c5e84a07af9e6a94 389 Gene3D G3DSA:3.30.1540.10 226 308 6.1E-24 T 06-07-2017 SMD11_RS03550 247d5f0daaf31cd9c5e84a07af9e6a94 389 SUPERFAMILY SSF89796 8 385 5.62E-118 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS03550 247d5f0daaf31cd9c5e84a07af9e6a94 389 Gene3D G3DSA:3.40.50.10540 309 383 2.3E-96 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS03550 247d5f0daaf31cd9c5e84a07af9e6a94 389 Gene3D G3DSA:3.40.50.10540 8 219 2.3E-96 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS03550 247d5f0daaf31cd9c5e84a07af9e6a94 389 Pfam PF02515 CoA-transferase family III 10 375 9.1E-113 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 SMD11_RS05395 b011deab679964918894d294bb345921 203 PIRSF PIRSF018427 13 199 1.0E-49 T 06-07-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 SMD11_RS05395 b011deab679964918894d294bb345921 203 Pfam PF00293 NUDIX domain 52 173 1.1E-23 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS05395 b011deab679964918894d294bb345921 203 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 26 197 30.142 T 06-07-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 SMD11_RS05395 b011deab679964918894d294bb345921 203 SUPERFAMILY SSF55811 28 188 7.72E-43 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS05395 b011deab679964918894d294bb345921 203 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 30 184 4.4E-35 T 06-07-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 SMD11_RS05395 b011deab679964918894d294bb345921 203 Gene3D G3DSA:3.90.79.10 28 190 3.0E-48 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS26005 dcccfdcf2c9c034ca7f1f94f0aca404a 338 PIRSF PIRSF001134 37 337 1.9E-93 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS26005 dcccfdcf2c9c034ca7f1f94f0aca404a 338 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 176 181 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD11_RS26005 dcccfdcf2c9c034ca7f1f94f0aca404a 338 Gene3D G3DSA:2.40.10.10 148 233 2.3E-21 T 06-07-2017 SMD11_RS26005 dcccfdcf2c9c034ca7f1f94f0aca404a 338 SUPERFAMILY SSF50494 152 331 3.91E-31 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS26005 dcccfdcf2c9c034ca7f1f94f0aca404a 338 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 174 188 1.4E-40 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS26005 dcccfdcf2c9c034ca7f1f94f0aca404a 338 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 237 257 1.4E-40 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS26005 dcccfdcf2c9c034ca7f1f94f0aca404a 338 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 277 300 1.4E-40 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS26005 dcccfdcf2c9c034ca7f1f94f0aca404a 338 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 258 275 1.4E-40 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS26005 dcccfdcf2c9c034ca7f1f94f0aca404a 338 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 301 315 1.4E-40 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS26005 dcccfdcf2c9c034ca7f1f94f0aca404a 338 Pfam PF00089 Trypsin 174 327 2.1E-9 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD11_RS26005 dcccfdcf2c9c034ca7f1f94f0aca404a 338 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 286 297 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site SMD11_RS26005 dcccfdcf2c9c034ca7f1f94f0aca404a 338 Gene3D G3DSA:3.30.300.50 76 140 1.3E-9 T 06-07-2017 SMD11_RS26005 dcccfdcf2c9c034ca7f1f94f0aca404a 338 Gene3D G3DSA:2.40.10.10 234 323 1.7E-27 T 06-07-2017 SMD11_RS26005 dcccfdcf2c9c034ca7f1f94f0aca404a 338 Pfam PF02983 Alpha-lytic protease prodomain 76 129 5.6E-14 T 06-07-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMD11_RS15625 759f73dcf9a0a8d449f871edc2eccf6f 199 SUPERFAMILY SSF111304 3 197 2.75E-74 T 06-07-2017 IPR023627 Recombination protein RecR SMD11_RS15625 759f73dcf9a0a8d449f871edc2eccf6f 199 Gene3D G3DSA:3.90.79.10 51 113 5.3E-4 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS15625 759f73dcf9a0a8d449f871edc2eccf6f 199 Pfam PF02132 RecR protein 38 77 3.1E-15 T 06-07-2017 IPR023628 Recombination protein RecR, C4-type zinc finger SMD11_RS15625 759f73dcf9a0a8d449f871edc2eccf6f 199 Pfam PF13662 Toprim domain 80 170 5.6E-26 T 06-07-2017 IPR006171 Toprim domain SMD11_RS15625 759f73dcf9a0a8d449f871edc2eccf6f 199 Pfam PF00633 Helix-hairpin-helix motif 2 27 4.7E-6 T 06-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 SMD11_RS15625 759f73dcf9a0a8d449f871edc2eccf6f 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 107.459 T 06-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 SMD11_RS15625 759f73dcf9a0a8d449f871edc2eccf6f 199 Gene3D G3DSA:3.40.50.140 114 169 4.3E-6 T 06-07-2017 IPR006171 Toprim domain SMD11_RS15625 759f73dcf9a0a8d449f871edc2eccf6f 199 SMART SM00493 79 164 2.8E-14 T 06-07-2017 IPR006171 Toprim domain SMD11_RS15625 759f73dcf9a0a8d449f871edc2eccf6f 199 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 5.6E-84 T 06-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 SMD11_RS15625 759f73dcf9a0a8d449f871edc2eccf6f 199 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 06-07-2017 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 SMD11_RS29375 72defbdb4b5a9735d2a7bb6c0d2355f1 377 SUPERFAMILY SSF53901 187 374 1.33E-47 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29375 72defbdb4b5a9735d2a7bb6c0d2355f1 377 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 213 1.9E-17 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS29375 72defbdb4b5a9735d2a7bb6c0d2355f1 377 Gene3D G3DSA:3.40.47.10 5 225 2.8E-24 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29375 72defbdb4b5a9735d2a7bb6c0d2355f1 377 SMART SM00825 Beta-ketoacyl synthase 11 376 6.3E-13 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS29375 72defbdb4b5a9735d2a7bb6c0d2355f1 377 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 222 332 3.8E-27 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS29375 72defbdb4b5a9735d2a7bb6c0d2355f1 377 SUPERFAMILY SSF53901 5 213 1.18E-29 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29375 72defbdb4b5a9735d2a7bb6c0d2355f1 377 Gene3D G3DSA:3.40.47.10 229 375 4.1E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS06725 1c34d4defea9415924b5ca9d0a369811 214 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 105 1.7E-17 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMD11_RS06725 1c34d4defea9415924b5ca9d0a369811 214 SUPERFAMILY SSF161098 11 196 5.36E-35 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS06725 1c34d4defea9415924b5ca9d0a369811 214 Gene3D G3DSA:1.10.3720.10 7 210 2.4E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS06725 1c34d4defea9415924b5ca9d0a369811 214 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 207 7.7E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS01495 4d99bfea97e89b0968140a4df438872b 251 SMART SM01110 16 241 3.9E-4 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 SMD11_RS01495 4d99bfea97e89b0968140a4df438872b 251 SUPERFAMILY SSF53474 28 213 6.45E-13 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01495 4d99bfea97e89b0968140a4df438872b 251 Pfam PF08237 PE-PPE domain 74 211 2.4E-15 T 06-07-2017 IPR013228 PE-PPE, C-terminal SMD11_RS01495 4d99bfea97e89b0968140a4df438872b 251 Gene3D G3DSA:3.40.50.1820 45 230 2.9E-17 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS24540 c99fc7d345bfa028147d1c4250fc687b 239 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 80 94 - T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 SMD11_RS24540 c99fc7d345bfa028147d1c4250fc687b 239 Pfam PF01168 Alanine racemase, N-terminal domain 12 236 4.0E-20 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS24540 c99fc7d345bfa028147d1c4250fc687b 239 Gene3D G3DSA:3.20.20.10 3 236 5.1E-76 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS24540 c99fc7d345bfa028147d1c4250fc687b 239 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 9 235 6.7E-38 T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 SMD11_RS24540 c99fc7d345bfa028147d1c4250fc687b 239 SUPERFAMILY SSF51419 4 233 7.63E-58 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS24540 c99fc7d345bfa028147d1c4250fc687b 239 PIRSF PIRSF004848 1 239 5.4E-62 T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 SMD11_RS26705 90ddda2dd12be50c3a087d9722951437 226 SUPERFAMILY SSF54364 20 93 3.53E-28 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SMD11_RS26705 90ddda2dd12be50c3a087d9722951437 226 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 22 185 3.2E-61 T 06-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SMD11_RS26705 90ddda2dd12be50c3a087d9722951437 226 Gene3D G3DSA:3.30.110.10 94 186 2.1E-38 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 SMD11_RS26705 90ddda2dd12be50c3a087d9722951437 226 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 22 91 7.9E-29 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SMD11_RS26705 90ddda2dd12be50c3a087d9722951437 226 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 16 185 29.674 T 06-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SMD11_RS26705 90ddda2dd12be50c3a087d9722951437 226 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 99 182 6.8E-34 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 SMD11_RS26705 90ddda2dd12be50c3a087d9722951437 226 Gene3D G3DSA:3.10.20.80 18 93 6.4E-35 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SMD11_RS26705 90ddda2dd12be50c3a087d9722951437 226 SUPERFAMILY SSF55200 100 184 4.58E-32 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 SMD11_RS08415 aa51173327727cf73a22e478e5c7accb 161 Pfam PF02780 Transketolase, C-terminal domain 38 144 3.8E-10 T 06-07-2017 IPR033248 Transketolase, C-terminal domain SMD11_RS08415 aa51173327727cf73a22e478e5c7accb 161 SUPERFAMILY SSF52922 18 154 9.29E-30 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS08415 aa51173327727cf73a22e478e5c7accb 161 Gene3D G3DSA:3.40.50.920 22 152 6.6E-37 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS16195 5b434768a08c610e495c980fb88b7058 388 PIRSF PIRSF000429 10 376 9.8E-23 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS16195 5b434768a08c610e495c980fb88b7058 388 SUPERFAMILY SSF53901 242 374 4.17E-14 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS16195 5b434768a08c610e495c980fb88b7058 388 Gene3D G3DSA:3.40.47.10 207 234 2.9E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS16195 5b434768a08c610e495c980fb88b7058 388 Gene3D G3DSA:3.40.47.10 16 119 2.9E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS16195 5b434768a08c610e495c980fb88b7058 388 Pfam PF00108 Thiolase, N-terminal domain 29 229 3.1E-6 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD11_RS16195 5b434768a08c610e495c980fb88b7058 388 SUPERFAMILY SSF53901 12 237 1.68E-22 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS20665 f03d1c221bb829c140b00986a72adbda 300 Gene3D G3DSA:1.10.340.30 116 223 3.7E-21 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD11_RS20665 f03d1c221bb829c140b00986a72adbda 300 SUPERFAMILY SSF48150 103 280 3.14E-29 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 2 312 41.265 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 163 309 2.6E-23 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 1.3E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 PRINTS PR00101 Aspartate carbamoyltransferase signature 226 235 1.3E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 1.3E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 1.3E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 PRINTS PR00101 Aspartate carbamoyltransferase signature 267 272 1.3E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 PRINTS PR00101 Aspartate carbamoyltransferase signature 291 305 1.3E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 Gene3D G3DSA:3.40.50.1370 143 288 4.6E-49 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 310 1.2E-90 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 Gene3D G3DSA:3.40.50.1370 2 142 3.2E-49 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 147 1.3E-39 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 9.9E-20 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 9.9E-20 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 9.9E-20 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 9.9E-20 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS27345 0bdc629e1cbb2bd57f5985845f80056d 328 SUPERFAMILY SSF53671 2 312 2.62E-93 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SMD11_RS07950 4118c1d35924aa2e6733b44d343eb95b 496 Gene3D G3DSA:3.40.50.150 283 449 6.0E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS07950 4118c1d35924aa2e6733b44d343eb95b 496 TIGRFAM TIGR04074 bacter_Hen1: 3' terminal RNA ribose 2'-O-methyltransferase Hen1 3 471 2.4E-207 T 06-07-2017 IPR024026 3'-RNA ribose 2'-O-methyltransferase, Hen1, bacterial SMD11_RS07950 4118c1d35924aa2e6733b44d343eb95b 496 Pfam PF12623 RNA repair, ligase-Pnkp-associating, region of Hen1 1 249 7.1E-113 T 06-07-2017 IPR024740 Hen1, N-terminal SMD11_RS07950 4118c1d35924aa2e6733b44d343eb95b 496 Pfam PF13649 Methyltransferase domain 296 385 4.8E-10 T 06-07-2017 SMD11_RS07950 4118c1d35924aa2e6733b44d343eb95b 496 SUPERFAMILY SSF53335 274 440 5.22E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS24485 ec6fde039e9167c04abfd728799182f4 652 Pfam PF03717 Penicillin-binding Protein dimerisation domain 100 267 2.2E-17 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SMD11_RS24485 ec6fde039e9167c04abfd728799182f4 652 Gene3D G3DSA:3.90.1310.10 203 293 5.0E-23 T 06-07-2017 SMD11_RS24485 ec6fde039e9167c04abfd728799182f4 652 SUPERFAMILY SSF56601 287 635 5.81E-86 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS24485 ec6fde039e9167c04abfd728799182f4 652 Pfam PF00905 Penicillin binding protein transpeptidase domain 312 627 3.9E-73 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD11_RS24485 ec6fde039e9167c04abfd728799182f4 652 SUPERFAMILY SSF56519 97 286 1.57E-31 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SMD11_RS24485 ec6fde039e9167c04abfd728799182f4 652 Gene3D G3DSA:3.40.710.10 294 631 1.1E-88 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 Pfam PF02867 Ribonucleotide reductase, barrel domain 224 747 3.3E-174 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 591 613 - T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 470 493 2.7E-49 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 602 629 2.7E-49 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 508 530 2.7E-49 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 300 319 2.7E-49 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 536 559 2.7E-49 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 432 443 2.7E-49 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 144 220 3.6E-18 T 06-07-2017 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 147 751 1.3E-223 T 06-07-2017 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 Gene3D G3DSA:3.20.70.20 396 556 2.7E-76 T 06-07-2017 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 Gene3D G3DSA:3.20.70.20 602 647 2.7E-76 T 06-07-2017 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 Gene3D G3DSA:3.20.70.20 148 346 2.7E-76 T 06-07-2017 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 Gene3D G3DSA:3.20.70.20 708 744 2.7E-76 T 06-07-2017 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 SUPERFAMILY SSF51998 223 651 4.88E-174 T 06-07-2017 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 SUPERFAMILY SSF51998 682 752 4.88E-174 T 06-07-2017 SMD11_RS11350 65a95cbcaebab3d94a2250ecf9640230 792 SUPERFAMILY SSF48168 23 222 2.75E-42 T 06-07-2017 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS13260 70cbbac70d23474a0a94df4664e153fd 384 SUPERFAMILY SSF52540 80 360 1.61E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13260 70cbbac70d23474a0a94df4664e153fd 384 Gene3D G3DSA:3.40.50.300 84 251 1.7E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13260 70cbbac70d23474a0a94df4664e153fd 384 Pfam PF07728 AAA domain (dynein-related subfamily) 102 240 3.3E-35 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 SMD11_RS20795 fe0925601c60cee9f80e3233aa493300 236 SUPERFAMILY SSF53271 126 236 5.45E-8 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS20795 fe0925601c60cee9f80e3233aa493300 236 Gene3D G3DSA:3.40.50.2020 125 236 2.4E-8 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS10240 ab4a1d5406148b3a3a25786d7f634d62 219 Pfam PF03458 UPF0126 domain 99 173 7.6E-19 T 06-07-2017 IPR005115 Uncharacterised domain UPF0126 SMD11_RS10240 ab4a1d5406148b3a3a25786d7f634d62 219 Pfam PF03458 UPF0126 domain 14 87 1.2E-19 T 06-07-2017 IPR005115 Uncharacterised domain UPF0126 SMD11_RS13480 02bc82ddc8cc113969b75eeb8755ac69 180 Pfam PF13508 Acetyltransferase (GNAT) domain 73 156 1.4E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS13480 02bc82ddc8cc113969b75eeb8755ac69 180 SUPERFAMILY SSF55729 26 177 7.72E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS13480 02bc82ddc8cc113969b75eeb8755ac69 180 Gene3D G3DSA:3.40.630.30 23 162 3.2E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS11510 d398389e00f88c1a7b1993ac555c6f15 155 Gene3D G3DSA:3.90.1170.40 21 154 8.9E-47 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS11510 d398389e00f88c1a7b1993ac555c6f15 155 SUPERFAMILY SSF54690 23 154 8.5E-41 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS11510 d398389e00f88c1a7b1993ac555c6f15 155 Pfam PF02391 MoaE protein 25 135 5.7E-36 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS04185 5098455547445cf6b1365969e5bbb295 178 ProSitePatterns PS01117 MarR-type HTH domain signature. 97 131 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site SMD11_RS04185 5098455547445cf6b1365969e5bbb295 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 114 7.0E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS04185 5098455547445cf6b1365969e5bbb295 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 134 7.0E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS04185 5098455547445cf6b1365969e5bbb295 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 148 168 7.0E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS04185 5098455547445cf6b1365969e5bbb295 178 Gene3D G3DSA:1.10.10.10 36 172 3.9E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04185 5098455547445cf6b1365969e5bbb295 178 Pfam PF12802 MarR family 61 122 1.1E-12 T 06-07-2017 SMD11_RS04185 5098455547445cf6b1365969e5bbb295 178 SMART SM00347 55 161 4.5E-19 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS04185 5098455547445cf6b1365969e5bbb295 178 SUPERFAMILY SSF46785 25 169 2.93E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33665 daff216d35c5d7a5d95c7b45cf726108 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 123 7.3E-5 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS33665 daff216d35c5d7a5d95c7b45cf726108 133 Gene3D G3DSA:3.10.180.10 7 130 6.7E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS33665 daff216d35c5d7a5d95c7b45cf726108 133 SUPERFAMILY SSF54593 8 129 3.66E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS10750 f707bf02ceb3f180eabfd61af9fb1a74 190 Pfam PF01923 Cobalamin adenosyltransferase 7 174 5.1E-52 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 SMD11_RS10750 f707bf02ceb3f180eabfd61af9fb1a74 190 Gene3D G3DSA:1.20.1200.10 16 188 1.4E-53 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 SMD11_RS10750 f707bf02ceb3f180eabfd61af9fb1a74 190 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 8 182 2.5E-46 T 06-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 SMD11_RS10750 f707bf02ceb3f180eabfd61af9fb1a74 190 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 13 184 4.0E-71 T 06-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 SMD11_RS10750 f707bf02ceb3f180eabfd61af9fb1a74 190 SUPERFAMILY SSF89028 6 185 4.32E-53 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 SMD11_RS04605 3691367e27ac225efb5f9e2485a47d11 50 Pfam PF00301 Rubredoxin 1 45 1.9E-20 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 SMD11_RS04605 3691367e27ac225efb5f9e2485a47d11 50 ProSitePatterns PS00202 Rubredoxin signature. 29 39 - T 06-07-2017 IPR018527 Rubredoxin, iron-binding site GO:0046872 SMD11_RS04605 3691367e27ac225efb5f9e2485a47d11 50 Gene3D G3DSA:2.20.28.10 1 47 1.2E-21 T 06-07-2017 IPR004039 Rubredoxin-type fold SMD11_RS04605 3691367e27ac225efb5f9e2485a47d11 50 SUPERFAMILY SSF57802 1 48 2.52E-19 T 06-07-2017 SMD11_RS25310 523ac898f8ee376fa481f9c34f11ef73 188 Pfam PF00583 Acetyltransferase (GNAT) family 70 145 1.2E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS25310 523ac898f8ee376fa481f9c34f11ef73 188 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 24 180 2.8E-60 T 06-07-2017 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 SMD11_RS25310 523ac898f8ee376fa481f9c34f11ef73 188 Gene3D G3DSA:3.40.630.30 22 181 8.2E-65 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS25310 523ac898f8ee376fa481f9c34f11ef73 188 SUPERFAMILY SSF55729 17 145 5.05E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS32435 0739b25d559bc6e83d1ecd258da5538f 256 SUPERFAMILY SSF51735 2 254 1.59E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32435 0739b25d559bc6e83d1ecd258da5538f 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.1E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32435 0739b25d559bc6e83d1ecd258da5538f 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.1E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32435 0739b25d559bc6e83d1ecd258da5538f 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.1E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32435 0739b25d559bc6e83d1ecd258da5538f 256 Gene3D G3DSA:3.40.50.720 3 253 2.9E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32435 0739b25d559bc6e83d1ecd258da5538f 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.6E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32435 0739b25d559bc6e83d1ecd258da5538f 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.6E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32435 0739b25d559bc6e83d1ecd258da5538f 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.6E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32435 0739b25d559bc6e83d1ecd258da5538f 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.6E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32435 0739b25d559bc6e83d1ecd258da5538f 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.6E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32435 0739b25d559bc6e83d1ecd258da5538f 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 2.6E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32435 0739b25d559bc6e83d1ecd258da5538f 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 252 2.8E-54 T 06-07-2017 SMD11_RS32900 15ee187275cc92a681a861b08cceda1f 303 SUPERFAMILY SSF55729 32 173 4.25E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS32900 15ee187275cc92a681a861b08cceda1f 303 Pfam PF00583 Acetyltransferase (GNAT) family 79 153 2.5E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS32900 15ee187275cc92a681a861b08cceda1f 303 Gene3D G3DSA:3.40.630.30 32 173 3.1E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS19070 ca6d0d148c3dcfeb0aec16a437699d6f 171 ProSitePatterns PS00360 Ribosomal protein S9 signature. 109 127 - T 06-07-2017 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 SMD11_RS19070 ca6d0d148c3dcfeb0aec16a437699d6f 171 SUPERFAMILY SSF54211 47 171 7.59E-42 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS19070 ca6d0d148c3dcfeb0aec16a437699d6f 171 Gene3D G3DSA:3.30.230.10 47 171 1.8E-46 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS19070 ca6d0d148c3dcfeb0aec16a437699d6f 171 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 41 171 32.714 T 06-07-2017 IPR023035 Ribosomal protein S9, bacterial/plastid SMD11_RS19070 ca6d0d148c3dcfeb0aec16a437699d6f 171 Pfam PF00380 Ribosomal protein S9/S16 50 171 7.5E-43 T 06-07-2017 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 SMD11_RS23845 b1760bb78baaeb58af7aecf8244f9f18 532 Gene3D G3DSA:2.60.40.420 407 530 4.2E-43 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS23845 b1760bb78baaeb58af7aecf8244f9f18 532 Pfam PF07731 Multicopper oxidase 422 528 4.5E-26 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 SMD11_RS23845 b1760bb78baaeb58af7aecf8244f9f18 532 Gene3D G3DSA:2.60.40.420 60 187 4.7E-33 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS23845 b1760bb78baaeb58af7aecf8244f9f18 532 SUPERFAMILY SSF49503 187 227 1.79E-28 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS23845 b1760bb78baaeb58af7aecf8244f9f18 532 SUPERFAMILY SSF49503 262 385 1.79E-28 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS23845 b1760bb78baaeb58af7aecf8244f9f18 532 Pfam PF00394 Multicopper oxidase 281 380 6.3E-20 T 06-07-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 SMD11_RS23845 b1760bb78baaeb58af7aecf8244f9f18 532 Gene3D G3DSA:2.60.40.420 189 225 1.1E-44 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS23845 b1760bb78baaeb58af7aecf8244f9f18 532 Gene3D G3DSA:2.60.40.420 259 394 1.1E-44 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS23845 b1760bb78baaeb58af7aecf8244f9f18 532 SUPERFAMILY SSF49503 413 527 1.89E-33 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS23845 b1760bb78baaeb58af7aecf8244f9f18 532 ProSitePatterns PS00079 Multicopper oxidases signature 1. 508 528 - T 06-07-2017 IPR033138 Multicopper oxidases, conserved site SMD11_RS23845 b1760bb78baaeb58af7aecf8244f9f18 532 Pfam PF07732 Multicopper oxidase 73 185 2.0E-32 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 SMD11_RS23845 b1760bb78baaeb58af7aecf8244f9f18 532 SUPERFAMILY SSF49503 65 202 5.69E-36 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS23845 b1760bb78baaeb58af7aecf8244f9f18 532 ProSitePatterns PS00080 Multicopper oxidases signature 2. 513 524 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 SMD11_RS34285 1711b6912ebfad670ef974efaa742e62 453 Gene3D G3DSA:3.30.470.20 237 327 6.6E-5 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS34285 1711b6912ebfad670ef974efaa742e62 453 Gene3D G3DSA:3.30.470.20 140 158 6.6E-5 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS34285 1711b6912ebfad670ef974efaa742e62 453 SUPERFAMILY SSF56059 142 336 8.94E-11 T 06-07-2017 SMD11_RS12585 5342341c4f362b4ccc7894ca5dbc8960 529 SUPERFAMILY SSF52096 251 529 1.83E-89 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS12585 5342341c4f362b4ccc7894ca5dbc8960 529 Pfam PF01039 Carboxyl transferase domain 36 527 2.2E-196 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS12585 5342341c4f362b4ccc7894ca5dbc8960 529 Gene3D G3DSA:3.90.226.10 278 529 3.1E-101 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS12585 5342341c4f362b4ccc7894ca5dbc8960 529 Gene3D G3DSA:3.90.226.10 7 264 3.6E-83 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS12585 5342341c4f362b4ccc7894ca5dbc8960 529 SUPERFAMILY SSF52096 13 264 1.99E-80 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS12585 5342341c4f362b4ccc7894ca5dbc8960 529 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 103 117 3.0E-5 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 SMD11_RS12585 5342341c4f362b4ccc7894ca5dbc8960 529 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 137 155 3.0E-5 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 SMD11_RS33290 f70725d92d7c79815354f83fee6c4c60 229 Gene3D G3DSA:1.10.10.10 2 58 2.1E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33290 f70725d92d7c79815354f83fee6c4c60 229 SMART SM00346 2 87 2.3E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS33290 f70725d92d7c79815354f83fee6c4c60 229 Pfam PF09339 IclR helix-turn-helix domain 2 50 4.7E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS33290 f70725d92d7c79815354f83fee6c4c60 229 SUPERFAMILY SSF55781 62 220 7.19E-9 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS33290 f70725d92d7c79815354f83fee6c4c60 229 Gene3D G3DSA:3.30.450.40 64 220 2.1E-8 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS33290 f70725d92d7c79815354f83fee6c4c60 229 SUPERFAMILY SSF46785 2 70 1.3E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS18925 849f2a52a59ea129cee87ac512064862 74 SUPERFAMILY SSF46561 5 67 2.88E-24 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18925 849f2a52a59ea129cee87ac512064862 74 Pfam PF00831 Ribosomal L29 protein 9 64 2.3E-26 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18925 849f2a52a59ea129cee87ac512064862 74 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 06-07-2017 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18925 849f2a52a59ea129cee87ac512064862 74 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 4.7E-23 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18925 849f2a52a59ea129cee87ac512064862 74 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 17.882 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18925 849f2a52a59ea129cee87ac512064862 74 Gene3D G3DSA:1.10.287.310 6 69 8.5E-32 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS03890 9dd48978994beb50d1b379b94696b3d8 434 Gene3D G3DSA:3.20.20.80 112 407 3.9E-25 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS03890 9dd48978994beb50d1b379b94696b3d8 434 SMART SM00636 98 405 5.6E-4 T 06-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 SMD11_RS03890 9dd48978994beb50d1b379b94696b3d8 434 SUPERFAMILY SSF51445 112 320 1.41E-28 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS03890 9dd48978994beb50d1b379b94696b3d8 434 SUPERFAMILY SSF51445 376 412 1.41E-28 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS03890 9dd48978994beb50d1b379b94696b3d8 434 Pfam PF00704 Glycosyl hydrolases family 18 156 403 8.1E-18 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 SMD11_RS15230 81e2ef38b5c2cd0b078879984ee27e6c 329 SMART SM00942 254 321 0.0015 T 06-07-2017 IPR014820 Primase, C-terminal 1 SMD11_RS15230 81e2ef38b5c2cd0b078879984ee27e6c 329 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 39 216 1.3E-44 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD11_RS15230 81e2ef38b5c2cd0b078879984ee27e6c 329 SMART SM00943 39 217 1.1E-42 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD11_RS15230 81e2ef38b5c2cd0b078879984ee27e6c 329 SUPERFAMILY SSF56747 34 225 7.85E-31 T 06-07-2017 SMD11_RS08555 ac989a06009a3e786b776a3b77359031 217 SUPERFAMILY SSF52172 2 172 3.37E-34 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS08555 ac989a06009a3e786b776a3b77359031 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 8.0E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS08555 ac989a06009a3e786b776a3b77359031 217 SMART SM00448 1 112 4.9E-33 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS08555 ac989a06009a3e786b776a3b77359031 217 Gene3D G3DSA:1.10.10.10 125 217 7.9E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08555 ac989a06009a3e786b776a3b77359031 217 SMART SM00862 145 217 7.2E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS08555 ac989a06009a3e786b776a3b77359031 217 Pfam PF00072 Response regulator receiver domain 3 113 4.3E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS08555 ac989a06009a3e786b776a3b77359031 217 Gene3D G3DSA:3.40.50.2300 2 119 1.7E-32 T 06-07-2017 SMD11_RS12220 4f8906bdc74791fd25241fe1e928ef76 791 Pfam PF02687 FtsX-like permease family 221 333 3.9E-7 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 SMD11_RS12220 4f8906bdc74791fd25241fe1e928ef76 791 Pfam PF02687 FtsX-like permease family 674 783 2.8E-6 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 SMD11_RS16055 7142ae622218f8865381e4c10ae43937 256 SUPERFAMILY SSF53474 20 210 7.19E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS16055 7142ae622218f8865381e4c10ae43937 256 Pfam PF07859 alpha/beta hydrolase fold 54 144 9.3E-5 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SMD11_RS16055 7142ae622218f8865381e4c10ae43937 256 Gene3D G3DSA:3.40.50.1820 19 214 1.2E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS10665 0ef39bdcadbb9dfd64d3b24b848b724c 321 Gene3D G3DSA:3.40.50.300 46 251 2.3E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10665 0ef39bdcadbb9dfd64d3b24b848b724c 321 Pfam PF03308 ArgK protein 20 280 1.9E-97 T 06-07-2017 SMD11_RS10665 0ef39bdcadbb9dfd64d3b24b848b724c 321 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 15 312 4.9E-104 T 06-07-2017 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS10665 0ef39bdcadbb9dfd64d3b24b848b724c 321 SUPERFAMILY SSF52540 3 307 2.07E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21615 e65db4ab474cf7b704ed6fa2b3b9cc8d 455 Gene3D G3DSA:3.40.50.300 22 239 3.5E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21615 e65db4ab474cf7b704ed6fa2b3b9cc8d 455 SUPERFAMILY SSF52540 35 264 5.03E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21615 e65db4ab474cf7b704ed6fa2b3b9cc8d 455 SUPERFAMILY SSF52540 295 406 5.03E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21615 e65db4ab474cf7b704ed6fa2b3b9cc8d 455 Pfam PF13245 Part of AAA domain 28 96 1.0E-10 T 06-07-2017 SMD11_RS32460 6bb16acd9b126bfbc7a7027f8169c8a7 543 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 136 151 - T 06-07-2017 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 SMD11_RS32460 6bb16acd9b126bfbc7a7027f8169c8a7 543 SUPERFAMILY SSF48557 2 531 2.98E-170 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 SMD11_RS32460 6bb16acd9b126bfbc7a7027f8169c8a7 543 Pfam PF00221 Aromatic amino acid lyase 6 490 4.7E-163 T 06-07-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 SMD11_RS32460 6bb16acd9b126bfbc7a7027f8169c8a7 543 Gene3D G3DSA:1.10.275.10 2 194 1.6E-66 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal SMD11_RS32460 6bb16acd9b126bfbc7a7027f8169c8a7 543 Gene3D G3DSA:1.20.200.10 195 523 1.2E-102 T 06-07-2017 SMD11_RS24370 bda67a2de0c9b112bb9599e45b95eff5 162 PIRSF PIRSF002560 1 157 2.1E-64 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD11_RS24370 bda67a2de0c9b112bb9599e45b95eff5 162 Pfam PF00210 Ferritin-like domain 8 143 9.8E-31 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 SMD11_RS24370 bda67a2de0c9b112bb9599e45b95eff5 162 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD11_RS24370 bda67a2de0c9b112bb9599e45b95eff5 162 SUPERFAMILY SSF47240 1 156 6.15E-46 T 06-07-2017 IPR009078 Ferritin-like superfamily SMD11_RS24370 bda67a2de0c9b112bb9599e45b95eff5 162 Gene3D G3DSA:1.20.1260.10 1 156 9.0E-53 T 06-07-2017 IPR012347 Ferritin-related SMD11_RS24370 bda67a2de0c9b112bb9599e45b95eff5 162 PRINTS PR00601 Bacterioferritin signature 23 43 1.4E-54 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD11_RS24370 bda67a2de0c9b112bb9599e45b95eff5 162 PRINTS PR00601 Bacterioferritin signature 3 22 1.4E-54 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD11_RS24370 bda67a2de0c9b112bb9599e45b95eff5 162 PRINTS PR00601 Bacterioferritin signature 107 127 1.4E-54 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD11_RS24370 bda67a2de0c9b112bb9599e45b95eff5 162 PRINTS PR00601 Bacterioferritin signature 128 149 1.4E-54 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD11_RS24370 bda67a2de0c9b112bb9599e45b95eff5 162 PRINTS PR00601 Bacterioferritin signature 86 106 1.4E-54 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD11_RS24370 bda67a2de0c9b112bb9599e45b95eff5 162 PRINTS PR00601 Bacterioferritin signature 44 64 1.4E-54 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD11_RS24370 bda67a2de0c9b112bb9599e45b95eff5 162 PRINTS PR00601 Bacterioferritin signature 65 85 1.4E-54 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD11_RS24370 bda67a2de0c9b112bb9599e45b95eff5 162 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 5.2E-62 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 SMD11_RS30365 bc7c09b729f44f188c768ae8da856796 353 Gene3D G3DSA:3.60.130.10 76 352 2.5E-28 T 06-07-2017 SMD11_RS30365 bc7c09b729f44f188c768ae8da856796 353 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 73 328 1.3E-25 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMD11_RS30365 bc7c09b729f44f188c768ae8da856796 353 SUPERFAMILY SSF51197 74 337 5.04E-37 T 06-07-2017 SMD11_RS27340 f8df3043ee9529e774ab318a02769d0d 196 SUPERFAMILY SSF53271 18 182 9.05E-41 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS27340 f8df3043ee9529e774ab318a02769d0d 196 Pfam PF00156 Phosphoribosyl transferase domain 18 158 2.8E-20 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMD11_RS27340 f8df3043ee9529e774ab318a02769d0d 196 Gene3D G3DSA:3.40.50.2020 19 183 5.8E-50 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS27340 f8df3043ee9529e774ab318a02769d0d 196 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 15 188 37.068 T 06-07-2017 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 SMD11_RS03525 0f85fc64459a60fd5285ee1e4b54e80b 367 Gene3D G3DSA:3.50.50.60 259 291 1.3E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03525 0f85fc64459a60fd5285ee1e4b54e80b 367 Gene3D G3DSA:3.50.50.60 153 213 1.3E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03525 0f85fc64459a60fd5285ee1e4b54e80b 367 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 6.8E-8 T 06-07-2017 SMD11_RS03525 0f85fc64459a60fd5285ee1e4b54e80b 367 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 6.8E-8 T 06-07-2017 SMD11_RS03525 0f85fc64459a60fd5285ee1e4b54e80b 367 SUPERFAMILY SSF51905 9 352 5.53E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03525 0f85fc64459a60fd5285ee1e4b54e80b 367 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 12 34 5.5E-14 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS03525 0f85fc64459a60fd5285ee1e4b54e80b 367 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 172 196 5.5E-14 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS03525 0f85fc64459a60fd5285ee1e4b54e80b 367 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 133 141 5.5E-14 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SMD11_RS03525 0f85fc64459a60fd5285ee1e4b54e80b 367 Gene3D G3DSA:3.50.50.60 9 152 2.0E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03525 0f85fc64459a60fd5285ee1e4b54e80b 367 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 14 211 1.8E-24 T 06-07-2017 SMD11_RS16715 5b7c2bc3503f9fe08d0763d5523dafb0 320 Gene3D G3DSA:1.10.260.40 40 117 8.9E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS16715 5b7c2bc3503f9fe08d0763d5523dafb0 320 SUPERFAMILY SSF47413 66 116 2.93E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS16715 5b7c2bc3503f9fe08d0763d5523dafb0 320 Pfam PF13560 Helix-turn-helix domain 42 121 8.5E-19 T 06-07-2017 SMD11_RS16715 5b7c2bc3503f9fe08d0763d5523dafb0 320 SMART SM00530 46 118 3.1E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS08480 01fcd70242baaef976cb6bec7f609296 229 Gene3D G3DSA:3.40.50.2300 1 121 3.3E-39 T 06-07-2017 SMD11_RS08480 01fcd70242baaef976cb6bec7f609296 229 Gene3D G3DSA:1.10.10.10 130 228 3.3E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08480 01fcd70242baaef976cb6bec7f609296 229 SMART SM00448 2 112 2.1E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS08480 01fcd70242baaef976cb6bec7f609296 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 5.4E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS08480 01fcd70242baaef976cb6bec7f609296 229 SMART SM00862 151 227 7.8E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS08480 01fcd70242baaef976cb6bec7f609296 229 Pfam PF00072 Response regulator receiver domain 4 112 2.4E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS08480 01fcd70242baaef976cb6bec7f609296 229 SUPERFAMILY SSF52172 2 184 7.83E-40 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS19370 ab7788da7aea44dabbac76ffd1d0cfc6 218 Pfam PF01613 Flavin reductase like domain 51 204 2.4E-35 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS19370 ab7788da7aea44dabbac76ffd1d0cfc6 218 Gene3D G3DSA:2.30.110.10 38 203 2.6E-53 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS19370 ab7788da7aea44dabbac76ffd1d0cfc6 218 SUPERFAMILY SSF50475 43 204 4.56E-44 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS19370 ab7788da7aea44dabbac76ffd1d0cfc6 218 SMART SM00903 50 204 4.9E-56 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS08550 f3988e3e0c5044a3a12f700a913052ff 420 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 267 7.7E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS08550 f3988e3e0c5044a3a12f700a913052ff 420 SUPERFAMILY SSF47384 186 267 1.96E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS08550 f3988e3e0c5044a3a12f700a913052ff 420 SUPERFAMILY SSF158472 149 198 2.22E-8 T 06-07-2017 SMD11_RS08550 f3988e3e0c5044a3a12f700a913052ff 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 225 239 1.9E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS08550 f3988e3e0c5044a3a12f700a913052ff 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 375 1.9E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS08550 f3988e3e0c5044a3a12f700a913052ff 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 400 1.9E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS08550 f3988e3e0c5044a3a12f700a913052ff 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 419 1.9E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS08550 f3988e3e0c5044a3a12f700a913052ff 420 SMART SM00304 148 201 1.2E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS08550 f3988e3e0c5044a3a12f700a913052ff 420 Pfam PF00672 HAMP domain 129 198 3.9E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS08550 f3988e3e0c5044a3a12f700a913052ff 420 Gene3D G3DSA:1.10.287.130 192 264 1.7E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS08550 f3988e3e0c5044a3a12f700a913052ff 420 SMART SM00387 310 420 6.0E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08550 f3988e3e0c5044a3a12f700a913052ff 420 SMART SM00388 202 268 8.4E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS08550 f3988e3e0c5044a3a12f700a913052ff 420 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 314 419 2.6E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08550 f3988e3e0c5044a3a12f700a913052ff 420 Gene3D G3DSA:3.30.565.10 271 419 7.8E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08550 f3988e3e0c5044a3a12f700a913052ff 420 SUPERFAMILY SSF55874 259 419 3.14E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS20115 7155c27780740c94c51d88aa42195707 349 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 197 314 1.8E-10 T 06-07-2017 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 SMD11_RS20115 7155c27780740c94c51d88aa42195707 349 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 155 172 - T 06-07-2017 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 SMD11_RS20115 7155c27780740c94c51d88aa42195707 349 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 105 179 8.8E-26 T 06-07-2017 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 SMD11_RS20115 7155c27780740c94c51d88aa42195707 349 SUPERFAMILY SSF54197 39 180 2.26E-47 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 SMD11_RS20115 7155c27780740c94c51d88aa42195707 349 PIRSF PIRSF000808 34 349 4.1E-99 T 06-07-2017 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 SMD11_RS20115 7155c27780740c94c51d88aa42195707 349 SUPERFAMILY SSF54197 188 347 6.99E-31 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 SMD11_RS20115 7155c27780740c94c51d88aa42195707 349 Gene3D G3DSA:3.30.428.10 65 179 9.4E-33 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 SMD11_RS20115 7155c27780740c94c51d88aa42195707 349 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 105 347 7.3E-36 T 06-07-2017 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 SMD11_RS20115 7155c27780740c94c51d88aa42195707 349 Gene3D G3DSA:3.30.428.10 188 347 8.4E-45 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 SMD11_RS03215 ab432d98dbc923c9ebc7aadb56bbdb34 320 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 196 278 4.9E-36 T 06-07-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 SMD11_RS03215 ab432d98dbc923c9ebc7aadb56bbdb34 320 SUPERFAMILY SSF52402 3 188 1.47E-36 T 06-07-2017 SMD11_RS03215 ab432d98dbc923c9ebc7aadb56bbdb34 320 Gene3D G3DSA:3.40.50.620 3 185 6.0E-39 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS03215 ab432d98dbc923c9ebc7aadb56bbdb34 320 Pfam PF01012 Electron transfer flavoprotein domain 4 171 2.0E-29 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SMD11_RS03215 ab432d98dbc923c9ebc7aadb56bbdb34 320 PIRSF PIRSF000089 1 320 9.9E-100 T 06-07-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 SMD11_RS03215 ab432d98dbc923c9ebc7aadb56bbdb34 320 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 259 285 - T 06-07-2017 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 SMD11_RS03215 ab432d98dbc923c9ebc7aadb56bbdb34 320 Gene3D G3DSA:3.40.50.1220 190 316 6.4E-59 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS03215 ab432d98dbc923c9ebc7aadb56bbdb34 320 SUPERFAMILY SSF52467 194 314 1.26E-47 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS03215 ab432d98dbc923c9ebc7aadb56bbdb34 320 SMART SM00893 4 187 5.5E-23 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 SMD11_RS01300 4a7bb68c760531492f7c03e9913270a9 403 Pfam PF00067 Cytochrome P450 186 375 3.7E-19 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS01300 4a7bb68c760531492f7c03e9913270a9 403 SUPERFAMILY SSF48264 10 402 2.1E-94 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS01300 4a7bb68c760531492f7c03e9913270a9 403 PRINTS PR00359 B-class P450 signature 93 104 2.4E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01300 4a7bb68c760531492f7c03e9913270a9 403 PRINTS PR00359 B-class P450 signature 156 171 2.4E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01300 4a7bb68c760531492f7c03e9913270a9 403 PRINTS PR00359 B-class P450 signature 346 355 2.4E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01300 4a7bb68c760531492f7c03e9913270a9 403 PRINTS PR00359 B-class P450 signature 297 324 2.4E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01300 4a7bb68c760531492f7c03e9913270a9 403 PRINTS PR00359 B-class P450 signature 355 366 2.4E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01300 4a7bb68c760531492f7c03e9913270a9 403 PRINTS PR00359 B-class P450 signature 325 340 2.4E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01300 4a7bb68c760531492f7c03e9913270a9 403 PRINTS PR00359 B-class P450 signature 139 155 2.4E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01300 4a7bb68c760531492f7c03e9913270a9 403 PRINTS PR00359 B-class P450 signature 280 291 2.4E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01300 4a7bb68c760531492f7c03e9913270a9 403 PRINTS PR00359 B-class P450 signature 199 221 2.4E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01300 4a7bb68c760531492f7c03e9913270a9 403 Gene3D G3DSA:1.10.630.10 7 402 8.3E-127 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS26365 fb45195a5d6742f2e6cfe653ab6ccfa2 234 Gene3D G3DSA:3.40.50.1240 1 215 1.0E-47 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS26365 fb45195a5d6742f2e6cfe653ab6ccfa2 234 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 202 7.3E-48 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS26365 fb45195a5d6742f2e6cfe653ab6ccfa2 234 SUPERFAMILY SSF53254 1 209 2.36E-46 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS26365 fb45195a5d6742f2e6cfe653ab6ccfa2 234 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 3 203 6.7E-96 T 06-07-2017 IPR022492 Phosphomutase MSMEG4193, putative SMD11_RS26365 fb45195a5d6742f2e6cfe653ab6ccfa2 234 SMART SM00855 3 162 3.5E-21 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS22280 afa8930ca01b00003bf7c4348f3d7bd0 361 Pfam PF01757 Acyltransferase family 34 330 2.5E-19 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 SMD11_RS22880 9cac1795d84fcfc65244c99b9eb0e234 272 SMART SM00382 47 241 2.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS22880 9cac1795d84fcfc65244c99b9eb0e234 272 SUPERFAMILY SSF52540 13 249 2.61E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22880 9cac1795d84fcfc65244c99b9eb0e234 272 Gene3D G3DSA:3.40.50.300 14 246 7.2E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22880 9cac1795d84fcfc65244c99b9eb0e234 272 Pfam PF00005 ABC transporter 38 185 3.3E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS27840 0db9a40071b545aad9c71fa06426f143 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 384 7.9E-49 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS27840 0db9a40071b545aad9c71fa06426f143 390 PIRSF PIRSF016578 5 390 2.0E-16 T 06-07-2017 SMD11_RS27840 0db9a40071b545aad9c71fa06426f143 390 Gene3D G3DSA:1.20.140.10 224 386 3.0E-68 T 06-07-2017 SMD11_RS27840 0db9a40071b545aad9c71fa06426f143 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 125 7.2E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS27840 0db9a40071b545aad9c71fa06426f143 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 224 3.3E-29 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS27840 0db9a40071b545aad9c71fa06426f143 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 132 144 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD11_RS27840 0db9a40071b545aad9c71fa06426f143 390 Gene3D G3DSA:2.40.110.10 129 223 2.7E-40 T 06-07-2017 SMD11_RS27840 0db9a40071b545aad9c71fa06426f143 390 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD11_RS27840 0db9a40071b545aad9c71fa06426f143 390 SUPERFAMILY SSF47203 234 386 3.87E-57 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS27840 0db9a40071b545aad9c71fa06426f143 390 SUPERFAMILY SSF56645 13 249 1.31E-74 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS27840 0db9a40071b545aad9c71fa06426f143 390 Gene3D G3DSA:1.10.540.10 15 125 3.6E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS17430 e07af4a5100b01b92bbf68c5b320ac83 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17430 e07af4a5100b01b92bbf68c5b320ac83 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17430 e07af4a5100b01b92bbf68c5b320ac83 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17430 e07af4a5100b01b92bbf68c5b320ac83 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 252 6.4E-58 T 06-07-2017 SMD11_RS17430 e07af4a5100b01b92bbf68c5b320ac83 253 SUPERFAMILY SSF51735 1 252 3.17E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17430 e07af4a5100b01b92bbf68c5b320ac83 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.0E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17430 e07af4a5100b01b92bbf68c5b320ac83 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.0E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17430 e07af4a5100b01b92bbf68c5b320ac83 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 3.0E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17430 e07af4a5100b01b92bbf68c5b320ac83 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.0E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17430 e07af4a5100b01b92bbf68c5b320ac83 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 3.0E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17430 e07af4a5100b01b92bbf68c5b320ac83 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.0E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS17430 e07af4a5100b01b92bbf68c5b320ac83 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS17430 e07af4a5100b01b92bbf68c5b320ac83 253 Gene3D G3DSA:3.40.50.720 2 252 3.8E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17430 e07af4a5100b01b92bbf68c5b320ac83 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 189 0.0038 T 06-07-2017 SMD11_RS32510 cd757fec3edd6010d1e515447eca897b 155 Pfam PF04892 VanZ like family 21 126 2.1E-21 T 06-07-2017 IPR006976 VanZ-like SMD11_RS32530 c34617f8af43b259bc5cef7b35dad73b 470 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 114 205 1.0E-8 T 06-07-2017 SMD11_RS32530 c34617f8af43b259bc5cef7b35dad73b 470 SUPERFAMILY SSF53335 110 282 2.18E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS32530 c34617f8af43b259bc5cef7b35dad73b 470 Gene3D G3DSA:3.40.50.150 120 249 1.9E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS30000 2065df65db613fe99b61619d5ba44c54 328 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 19 314 1.3E-35 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMD11_RS30000 2065df65db613fe99b61619d5ba44c54 328 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 1 324 1.4E-121 T 06-07-2017 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB SMD11_RS30000 2065df65db613fe99b61619d5ba44c54 328 PIRSF PIRSF001439 1 324 7.2E-63 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMD11_RS30000 2065df65db613fe99b61619d5ba44c54 328 SUPERFAMILY SSF51735 1 323 1.36E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30000 2065df65db613fe99b61619d5ba44c54 328 Gene3D G3DSA:3.30.1780.10 1 144 3.5E-36 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 SMD11_RS30000 2065df65db613fe99b61619d5ba44c54 328 Gene3D G3DSA:3.40.50.720 145 296 3.7E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS02530 9da2d82165209f7bf0f8a97cccabdb2f 152 SUPERFAMILY SSF46785 15 145 5.61E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02530 9da2d82165209f7bf0f8a97cccabdb2f 152 Gene3D G3DSA:1.10.10.10 15 145 1.0E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33545 0122730233e891f3caccb0c70981f556 245 Pfam PF06314 Acetoacetate decarboxylase (ADC) 12 243 1.2E-71 T 06-07-2017 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 SMD11_RS33545 0122730233e891f3caccb0c70981f556 245 SUPERFAMILY SSF160104 2 243 5.49E-80 T 06-07-2017 SMD11_RS33545 0122730233e891f3caccb0c70981f556 245 Gene3D G3DSA:2.40.400.10 13 244 8.6E-83 T 06-07-2017 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 SMD11_RS12565 527e16efbc8573cdcd486da4c2e83997 380 Gene3D G3DSA:3.30.450.40 2 177 1.4E-12 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS12565 527e16efbc8573cdcd486da4c2e83997 380 Gene3D G3DSA:3.30.70.270 185 338 2.3E-32 T 06-07-2017 SMD11_RS12565 527e16efbc8573cdcd486da4c2e83997 380 Pfam PF00990 Diguanylate cyclase, GGDEF domain 183 335 5.1E-25 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS12565 527e16efbc8573cdcd486da4c2e83997 380 Pfam PF01590 GAF domain 110 168 4.0E-5 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS12565 527e16efbc8573cdcd486da4c2e83997 380 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 181 336 2.6E-24 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS12565 527e16efbc8573cdcd486da4c2e83997 380 SMART SM00267 172 342 1.7E-44 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS12565 527e16efbc8573cdcd486da4c2e83997 380 SUPERFAMILY SSF55073 188 335 2.12E-28 T 06-07-2017 IPR029787 Nucleotide cyclase SMD11_RS12565 527e16efbc8573cdcd486da4c2e83997 380 SUPERFAMILY SSF55781 12 173 4.14E-12 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 SMART SM00434 35 492 7.3E-280 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 Gene3D G3DSA:3.90.199.10 361 425 8.9E-114 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 Gene3D G3DSA:3.90.199.10 54 263 8.9E-114 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 32 839 0.0 T 06-07-2017 SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 SUPERFAMILY SSF56719 54 514 3.79E-170 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 Gene3D G3DSA:2.120.10.90 524 838 1.6E-118 T 06-07-2017 SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 Gene3D G3DSA:3.30.1360.40 264 360 7.1E-34 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 26 841 23.133 T 06-07-2017 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 SUPERFAMILY SSF101904 526 847 1.83E-98 T 06-07-2017 SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 56 496 1.1E-150 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 531 576 8.9E-14 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 582 628 3.4E-9 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 793 837 3.3E-11 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 690 738 1.2E-11 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 638 674 3.2E-7 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD11_RS16940 ac832972b2aac9019eb3faaba0c9ed44 876 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 744 789 5.4E-13 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD11_RS28540 4e98af8e595b38784fe18f8967a5ef32 208 SUPERFAMILY SSF51182 69 176 1.31E-21 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS28540 4e98af8e595b38784fe18f8967a5ef32 208 SUPERFAMILY SSF47413 5 79 1.39E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS28540 4e98af8e595b38784fe18f8967a5ef32 208 Gene3D G3DSA:1.10.260.40 11 83 8.1E-23 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS28540 4e98af8e595b38784fe18f8967a5ef32 208 Pfam PF07883 Cupin domain 111 176 1.9E-15 T 06-07-2017 IPR013096 Cupin 2, conserved barrel SMD11_RS28540 4e98af8e595b38784fe18f8967a5ef32 208 SMART SM00530 17 72 5.9E-18 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS28540 4e98af8e595b38784fe18f8967a5ef32 208 Gene3D G3DSA:2.60.120.10 90 177 5.0E-14 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS28540 4e98af8e595b38784fe18f8967a5ef32 208 Pfam PF13560 Helix-turn-helix domain 14 72 1.5E-16 T 06-07-2017 SMD11_RS16855 453c0875ce561e184f4593e4ab29d4bc 109 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 5.5E-37 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMD11_RS16855 453c0875ce561e184f4593e4ab29d4bc 109 Pfam PF00085 Thioredoxin 4 102 3.0E-32 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 SMD11_RS16855 453c0875ce561e184f4593e4ab29d4bc 109 ProSitePatterns PS00194 Thioredoxin family active site. 23 41 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 SMD11_RS16855 453c0875ce561e184f4593e4ab29d4bc 109 PIRSF PIRSF000077 1 106 7.8E-43 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMD11_RS16855 453c0875ce561e184f4593e4ab29d4bc 109 SUPERFAMILY SSF52833 4 106 3.06E-37 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS16855 453c0875ce561e184f4593e4ab29d4bc 109 Gene3D G3DSA:3.40.30.10 3 102 2.7E-37 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS16855 453c0875ce561e184f4593e4ab29d4bc 109 PRINTS PR00421 Thioredoxin family signature 22 30 9.3E-8 T 06-07-2017 SMD11_RS16855 453c0875ce561e184f4593e4ab29d4bc 109 PRINTS PR00421 Thioredoxin family signature 30 39 9.3E-8 T 06-07-2017 SMD11_RS16855 453c0875ce561e184f4593e4ab29d4bc 109 PRINTS PR00421 Thioredoxin family signature 70 81 9.3E-8 T 06-07-2017 SMD11_RS09690 c2702d41ee13c42af574a0055df6494b 300 Gene3D G3DSA:3.20.190.10 2 141 7.3E-37 T 06-07-2017 SMD11_RS09690 c2702d41ee13c42af574a0055df6494b 300 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 295 41.389 T 06-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 SMD11_RS09690 c2702d41ee13c42af574a0055df6494b 300 SUPERFAMILY SSF81624 2 139 5.76E-34 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD11_RS09690 c2702d41ee13c42af574a0055df6494b 300 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 154 241 1.5E-22 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD11_RS09690 c2702d41ee13c42af574a0055df6494b 300 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 133 2.2E-33 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD11_RS09690 c2702d41ee13c42af574a0055df6494b 300 SUPERFAMILY SSF46946 154 243 2.65E-27 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMD11_RS09690 c2702d41ee13c42af574a0055df6494b 300 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 294 2.4E-85 T 06-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 SMD11_RS09690 c2702d41ee13c42af574a0055df6494b 300 SUPERFAMILY SSF57716 246 295 8.27E-16 T 06-07-2017 SMD11_RS09690 c2702d41ee13c42af574a0055df6494b 300 Pfam PF06827 Zinc finger found in FPG and IleRS 268 294 1.1E-4 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 SMD11_RS09690 c2702d41ee13c42af574a0055df6494b 300 SMART SM01232 154 246 4.0E-44 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD11_RS09690 c2702d41ee13c42af574a0055df6494b 300 Gene3D G3DSA:1.10.8.50 156 295 4.9E-47 T 06-07-2017 SMD11_RS09690 c2702d41ee13c42af574a0055df6494b 300 ProSitePatterns PS01242 Zinc finger FPG-type signature. 270 294 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 SMD11_RS09690 c2702d41ee13c42af574a0055df6494b 300 SMART SM00898 2 135 1.8E-49 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD11_RS21075 a1abb55d0f5ddfaa9ca7dffb847e08e8 407 Pfam PF00082 Subtilase family 58 309 2.3E-43 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS21075 a1abb55d0f5ddfaa9ca7dffb847e08e8 407 SUPERFAMILY SSF52743 40 320 3.53E-73 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS21075 a1abb55d0f5ddfaa9ca7dffb847e08e8 407 PRINTS PR00723 Subtilisin serine protease family (S8) signature 97 110 4.4E-13 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS21075 a1abb55d0f5ddfaa9ca7dffb847e08e8 407 PRINTS PR00723 Subtilisin serine protease family (S8) signature 257 273 4.4E-13 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS21075 a1abb55d0f5ddfaa9ca7dffb847e08e8 407 PRINTS PR00723 Subtilisin serine protease family (S8) signature 58 77 4.4E-13 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS21075 a1abb55d0f5ddfaa9ca7dffb847e08e8 407 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 47 402 2.6E-90 T 06-07-2017 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 SMD11_RS21075 a1abb55d0f5ddfaa9ca7dffb847e08e8 407 Gene3D G3DSA:3.40.50.200 30 318 2.1E-73 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS09210 8364a2dcadd34e6dbeb1caa012aeea42 821 SUPERFAMILY SSF52540 500 734 4.35E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09210 8364a2dcadd34e6dbeb1caa012aeea42 821 Gene3D G3DSA:3.40.50.300 501 732 4.3E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09210 8364a2dcadd34e6dbeb1caa012aeea42 821 Pfam PF13614 AAA domain 502 652 1.3E-11 T 06-07-2017 IPR025669 AAA domain SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 Pfam PF00067 Cytochrome P450 202 370 2.0E-22 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 Gene3D G3DSA:1.10.630.10 11 400 2.6E-135 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 PRINTS PR00385 P450 superfamily signature 237 254 1.2E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 PRINTS PR00385 P450 superfamily signature 349 360 1.2E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 PRINTS PR00385 P450 superfamily signature 340 349 1.2E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 PRINTS PR00385 P450 superfamily signature 272 283 1.2E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 SUPERFAMILY SSF48264 15 400 6.29E-102 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 PRINTS PR00359 B-class P450 signature 89 100 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 PRINTS PR00359 B-class P450 signature 190 212 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 PRINTS PR00359 B-class P450 signature 137 153 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 PRINTS PR00359 B-class P450 signature 154 169 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 PRINTS PR00359 B-class P450 signature 340 349 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 PRINTS PR00359 B-class P450 signature 319 334 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 PRINTS PR00359 B-class P450 signature 349 360 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06870 9d93ba3afe4139929174445e9fef2672 400 PRINTS PR00359 B-class P450 signature 272 283 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31175 7d5b1f20ec7bd25bb1dd8d509e43d685 383 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 20 381 3.0E-170 T 06-07-2017 SMD11_RS31175 7d5b1f20ec7bd25bb1dd8d509e43d685 383 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 382 8.1E-103 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD11_RS31175 7d5b1f20ec7bd25bb1dd8d509e43d685 383 Pfam PF01960 ArgJ family 11 383 9.7E-126 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD11_RS31175 7d5b1f20ec7bd25bb1dd8d509e43d685 383 Gene3D G3DSA:3.60.70.12 2 259 7.0E-94 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD11_RS31175 7d5b1f20ec7bd25bb1dd8d509e43d685 383 SUPERFAMILY SSF56266 7 379 2.09E-126 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD11_RS31175 7d5b1f20ec7bd25bb1dd8d509e43d685 383 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 383 131.818 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD11_RS16050 6efee4dec4b7d8d37465333d94f23889 490 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 55 88 - T 06-07-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 SMD11_RS16050 6efee4dec4b7d8d37465333d94f23889 490 Pfam PF01565 FAD binding domain 55 187 3.5E-30 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD11_RS16050 6efee4dec4b7d8d37465333d94f23889 490 Gene3D G3DSA:3.30.465.10 114 220 5.2E-12 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS16050 6efee4dec4b7d8d37465333d94f23889 490 Pfam PF08031 Berberine and berberine like 446 489 2.3E-16 T 06-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 SMD11_RS16050 6efee4dec4b7d8d37465333d94f23889 490 SUPERFAMILY SSF56176 20 220 3.55E-49 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS16050 6efee4dec4b7d8d37465333d94f23889 490 Gene3D G3DSA:3.30.43.10 52 110 3.7E-12 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS24395 d7226fa46702ec7da41c939589e1b712 79 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 16 79 5.0E-21 T 06-07-2017 IPR010035 ThiS, thiamine-biosynthesis SMD11_RS24395 d7226fa46702ec7da41c939589e1b712 79 Pfam PF02597 ThiS family 17 79 1.2E-13 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 SMD11_RS24395 d7226fa46702ec7da41c939589e1b712 79 SUPERFAMILY SSF54285 16 78 3.05E-15 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp SMD11_RS24395 d7226fa46702ec7da41c939589e1b712 79 Gene3D G3DSA:3.10.20.30 16 79 4.5E-24 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 967 1167 9.3E-41 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 Gene3D G3DSA:3.20.20.330 12 356 1.1E-102 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 SMART SM01018 647 729 2.7E-40 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 SUPERFAMILY SSF47644 647 728 9.29E-24 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 PIRSF PIRSF000381 10 1169 0.0 T 06-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 Pfam PF02310 B12 binding domain 735 851 2.1E-20 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 SUPERFAMILY SSF52242 729 864 1.23E-38 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 SUPERFAMILY SSF51717 349 620 2.22E-73 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 SUPERFAMILY SSF56507 896 1168 2.22E-93 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 Pfam PF00809 Pterin binding enzyme 352 588 2.7E-45 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 Gene3D G3DSA:3.40.50.280 731 862 1.2E-46 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 Pfam PF02607 B12 binding domain 650 722 5.5E-25 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 TIGRFAM TIGR02082 metH: methionine synthase 22 1167 0.0 T 06-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 Gene3D G3DSA:1.10.1240.10 642 726 6.4E-31 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 SUPERFAMILY SSF82282 16 391 1.31E-102 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 Gene3D G3DSA:3.10.196.10 943 1167 2.8E-72 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 Pfam PF02574 Homocysteine S-methyltransferase 26 317 3.5E-65 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMD11_RS26410 226233e30080d4d18ee7a1f5fcc028d7 1169 Gene3D G3DSA:3.20.20.20 357 619 2.1E-84 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS08290 42df82c4f0f2c83bf9b2bf432ae84163 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 1.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS08290 42df82c4f0f2c83bf9b2bf432ae84163 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 1.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS08290 42df82c4f0f2c83bf9b2bf432ae84163 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 1.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS08290 42df82c4f0f2c83bf9b2bf432ae84163 210 Gene3D G3DSA:3.40.50.2300 1 120 3.1E-41 T 06-07-2017 SMD11_RS08290 42df82c4f0f2c83bf9b2bf432ae84163 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 161 188 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS08290 42df82c4f0f2c83bf9b2bf432ae84163 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 200 8.9E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS08290 42df82c4f0f2c83bf9b2bf432ae84163 210 SUPERFAMILY SSF52172 1 131 9.82E-37 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS08290 42df82c4f0f2c83bf9b2bf432ae84163 210 SUPERFAMILY SSF46894 141 208 5.44E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS08290 42df82c4f0f2c83bf9b2bf432ae84163 210 SMART SM00421 144 201 5.0E-24 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS08290 42df82c4f0f2c83bf9b2bf432ae84163 210 Pfam PF00072 Response regulator receiver domain 4 115 2.6E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS08290 42df82c4f0f2c83bf9b2bf432ae84163 210 SMART SM00448 2 115 1.3E-33 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS08290 42df82c4f0f2c83bf9b2bf432ae84163 210 Gene3D G3DSA:1.10.10.10 121 208 1.9E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS18850 8b2a9cc4c21eda12046180da642d17e3 1299 SUPERFAMILY SSF64484 5 1251 0.0 T 06-07-2017 SMD11_RS18850 8b2a9cc4c21eda12046180da642d17e3 1299 Pfam PF04998 RNA polymerase Rpb1, domain 5 838 1199 3.1E-67 T 06-07-2017 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18850 8b2a9cc4c21eda12046180da642d17e3 1299 Gene3D G3DSA:2.40.40.20 492 564 3.7E-38 T 06-07-2017 SMD11_RS18850 8b2a9cc4c21eda12046180da642d17e3 1299 Gene3D G3DSA:2.40.40.20 424 451 3.7E-38 T 06-07-2017 SMD11_RS18850 8b2a9cc4c21eda12046180da642d17e3 1299 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 1.4E-81 T 06-07-2017 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18850 8b2a9cc4c21eda12046180da642d17e3 1299 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 731 2.0E-21 T 06-07-2017 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18850 8b2a9cc4c21eda12046180da642d17e3 1299 Gene3D G3DSA:2.40.50.100 1041 1095 1.8E-9 T 06-07-2017 SMD11_RS18850 8b2a9cc4c21eda12046180da642d17e3 1299 Pfam PF00623 RNA polymerase Rpb1, domain 2 468 560 9.6E-28 T 06-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18850 8b2a9cc4c21eda12046180da642d17e3 1299 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 480 1.3E-8 T 06-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18850 8b2a9cc4c21eda12046180da642d17e3 1299 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1251 0.0 T 06-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18850 8b2a9cc4c21eda12046180da642d17e3 1299 Pfam PF05000 RNA polymerase Rpb1, domain 4 760 824 7.1E-14 T 06-07-2017 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18850 8b2a9cc4c21eda12046180da642d17e3 1299 SMART SM00663 310 589 2.3E-174 T 06-07-2017 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS18850 8b2a9cc4c21eda12046180da642d17e3 1299 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 5 1260 10.0 T 06-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SMD11_RS05200 6fc7c3a51b8d2051b77fcdd111f22377 139 Gene3D G3DSA:3.90.79.10 10 135 5.1E-20 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS05200 6fc7c3a51b8d2051b77fcdd111f22377 139 SUPERFAMILY SSF55811 4 135 7.18E-23 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS05200 6fc7c3a51b8d2051b77fcdd111f22377 139 PRINTS PR00502 NUDIX hydrolase family signature 33 47 5.9E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS05200 6fc7c3a51b8d2051b77fcdd111f22377 139 PRINTS PR00502 NUDIX hydrolase family signature 48 63 5.9E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS05200 6fc7c3a51b8d2051b77fcdd111f22377 139 Pfam PF00293 NUDIX domain 9 124 2.8E-13 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS12660 0598290e798702e09156c5edef7ad3bc 271 Pfam PF01048 Phosphorylase superfamily 33 268 8.3E-41 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD11_RS12660 0598290e798702e09156c5edef7ad3bc 271 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 86 127 - T 06-07-2017 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 SMD11_RS12660 0598290e798702e09156c5edef7ad3bc 271 Gene3D G3DSA:3.40.50.1580 10 270 8.4E-90 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD11_RS12660 0598290e798702e09156c5edef7ad3bc 271 SUPERFAMILY SSF53167 14 271 8.25E-79 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD11_RS12660 0598290e798702e09156c5edef7ad3bc 271 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 32 268 1.3E-101 T 06-07-2017 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 SMD11_RS12660 0598290e798702e09156c5edef7ad3bc 271 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 32 268 1.9E-74 T 06-07-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 SMD11_RS12660 0598290e798702e09156c5edef7ad3bc 271 PIRSF PIRSF000477 4 271 1.5E-88 T 06-07-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 SMD11_RS01180 47c7bcb69a7442d6c715042ca6fb80fa 635 Gene3D G3DSA:3.40.50.980 22 113 5.1E-16 T 06-07-2017 SMD11_RS01180 47c7bcb69a7442d6c715042ca6fb80fa 635 Gene3D G3DSA:2.30.38.10 276 338 1.3E-16 T 06-07-2017 SMD11_RS01180 47c7bcb69a7442d6c715042ca6fb80fa 635 SUPERFAMILY SSF56801 21 427 1.44E-73 T 06-07-2017 SMD11_RS01180 47c7bcb69a7442d6c715042ca6fb80fa 635 Pfam PF00501 AMP-binding enzyme 21 344 5.6E-51 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS01180 47c7bcb69a7442d6c715042ca6fb80fa 635 Gene3D G3DSA:3.40.50.980 114 258 1.0E-28 T 06-07-2017 SMD11_RS05375 356bddcd1d50a03190d154116ec03d99 245 Pfam PF00483 Nucleotidyl transferase 3 149 6.7E-12 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMD11_RS05375 356bddcd1d50a03190d154116ec03d99 245 Gene3D G3DSA:3.90.550.10 2 238 1.6E-35 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS05375 356bddcd1d50a03190d154116ec03d99 245 SUPERFAMILY SSF53448 1 237 9.24E-34 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS31485 da1701fddd6c2d038bae3353a2927cd8 681 Pfam PF00005 ABC transporter 440 593 1.2E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS31485 da1701fddd6c2d038bae3353a2927cd8 681 Gene3D G3DSA:3.40.50.300 423 656 1.8E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31485 da1701fddd6c2d038bae3353a2927cd8 681 Gene3D G3DSA:1.20.1560.10 90 388 1.1E-10 T 06-07-2017 SMD11_RS31485 da1701fddd6c2d038bae3353a2927cd8 681 SUPERFAMILY SSF90123 88 388 1.44E-15 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS31485 da1701fddd6c2d038bae3353a2927cd8 681 SUPERFAMILY SSF90123 569 576 1.44E-15 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS31485 da1701fddd6c2d038bae3353a2927cd8 681 SMART SM00382 449 639 5.0E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS31485 da1701fddd6c2d038bae3353a2927cd8 681 ProSitePatterns PS00211 ABC transporters family signature. 565 579 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS31485 da1701fddd6c2d038bae3353a2927cd8 681 SUPERFAMILY SSF52540 421 663 2.11E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09730 1b6faac1b06f28f18e2985f98963e05e 733 Gene3D G3DSA:3.40.50.300 469 669 9.1E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09730 1b6faac1b06f28f18e2985f98963e05e 733 SUPERFAMILY SSF50249 15 182 9.85E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS09730 1b6faac1b06f28f18e2985f98963e05e 733 SMART SM00490 536 621 4.9E-22 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS09730 1b6faac1b06f28f18e2985f98963e05e 733 Gene3D G3DSA:3.40.50.300 262 468 2.8E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09730 1b6faac1b06f28f18e2985f98963e05e 733 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 28 698 1.3E-198 T 06-07-2017 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 SMD11_RS09730 1b6faac1b06f28f18e2985f98963e05e 733 SMART SM00487 272 486 2.2E-31 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS09730 1b6faac1b06f28f18e2985f98963e05e 733 SUPERFAMILY SSF52540 406 631 4.31E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09730 1b6faac1b06f28f18e2985f98963e05e 733 SUPERFAMILY SSF52540 193 467 4.3E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09730 1b6faac1b06f28f18e2985f98963e05e 733 Pfam PF00271 Helicase conserved C-terminal domain 544 620 4.5E-19 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS09730 1b6faac1b06f28f18e2985f98963e05e 733 Pfam PF00270 DEAD/DEAH box helicase 297 450 1.8E-15 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD11_RS09730 1b6faac1b06f28f18e2985f98963e05e 733 Gene3D G3DSA:2.40.50.140 48 142 4.8E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS09730 1b6faac1b06f28f18e2985f98963e05e 733 Pfam PF17191 RecG wedge domain 16 137 3.8E-9 T 06-07-2017 IPR033454 RecG, wedge domain SMD11_RS01600 6640eb9f97aa3eba0a5cfb3d6379886b 366 Pfam PF01758 Sodium Bile acid symporter family 66 261 2.5E-60 T 06-07-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 SMD11_RS01600 6640eb9f97aa3eba0a5cfb3d6379886b 366 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 19 348 1.4E-129 T 06-07-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 SMD11_RS01600 6640eb9f97aa3eba0a5cfb3d6379886b 366 PIRSF PIRSF005508 6 365 2.1E-135 T 06-07-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 Gene3D G3DSA:4.10.860.10 657 705 2.6E-12 T 06-07-2017 IPR001943 UVR domain GO:0005515 SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 Gene3D G3DSA:3.40.50.300 396 416 1.1E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 Gene3D G3DSA:3.40.50.300 15 98 1.1E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 Gene3D G3DSA:3.40.50.300 286 346 1.1E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 Pfam PF00271 Helicase conserved C-terminal domain 439 552 1.3E-19 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 Pfam PF12344 Ultra-violet resistance protein B 559 600 7.1E-21 T 06-07-2017 IPR024759 UvrB, YAD/RRR-motif-containing domain SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 SUPERFAMILY SSF46600 661 704 3.01E-9 T 06-07-2017 IPR001943 UVR domain GO:0005515 SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 Gene3D G3DSA:3.40.50.300 426 589 3.9E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 Gene3D G3DSA:3.30.2060.10 169 237 2.1E-11 T 06-07-2017 SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 Pfam PF02151 UvrB/uvrC motif 667 701 3.7E-6 T 06-07-2017 IPR001943 UVR domain GO:0005515 SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 Pfam PF04851 Type III restriction enzyme, res subunit 24 134 5.6E-9 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 SUPERFAMILY SSF52540 13 422 7.71E-134 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 14 699 0.0 T 06-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 Hamap MF_00204 UvrABC system protein B [uvrB]. 12 701 42.447 T 06-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 SMART SM00487 18 433 1.9E-26 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 SUPERFAMILY SSF52540 42 91 1.11E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 SUPERFAMILY SSF52540 466 587 1.11E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25030 563519b32bfe761cd91e5b64139af95e 711 SMART SM00490 467 553 2.5E-18 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS12250 b5822d91fcc19b32c18d2c342aae7b0e 440 SUPERFAMILY SSF52540 229 393 8.21E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12250 b5822d91fcc19b32c18d2c342aae7b0e 440 Pfam PF02562 PhoH-like protein 230 435 1.9E-54 T 06-07-2017 IPR003714 PhoH-like protein GO:0005524 SMD11_RS12250 b5822d91fcc19b32c18d2c342aae7b0e 440 Pfam PF13638 PIN domain 15 153 2.5E-25 T 06-07-2017 IPR002716 PIN domain SMD11_RS12250 b5822d91fcc19b32c18d2c342aae7b0e 440 Gene3D G3DSA:3.40.50.300 229 435 4.7E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12250 b5822d91fcc19b32c18d2c342aae7b0e 440 SUPERFAMILY SSF88723 105 151 8.41E-8 T 06-07-2017 IPR029060 PIN domain-like SMD11_RS12250 b5822d91fcc19b32c18d2c342aae7b0e 440 SUPERFAMILY SSF88723 14 72 8.41E-8 T 06-07-2017 IPR029060 PIN domain-like SMD11_RS12250 b5822d91fcc19b32c18d2c342aae7b0e 440 Gene3D G3DSA:3.40.50.1010 105 153 1.2E-9 T 06-07-2017 IPR029060 PIN domain-like SMD11_RS12250 b5822d91fcc19b32c18d2c342aae7b0e 440 Gene3D G3DSA:3.40.50.1010 14 72 1.2E-9 T 06-07-2017 IPR029060 PIN domain-like SMD11_RS12250 b5822d91fcc19b32c18d2c342aae7b0e 440 SMART SM00670 13 140 1.2E-13 T 06-07-2017 IPR002716 PIN domain SMD11_RS13910 b880210af9ec2f9cb61c70ce6b1c9bf5 68 PRINTS PR00050 Cold shock protein signature 24 33 1.2E-19 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS13910 b880210af9ec2f9cb61c70ce6b1c9bf5 68 PRINTS PR00050 Cold shock protein signature 39 57 1.2E-19 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS13910 b880210af9ec2f9cb61c70ce6b1c9bf5 68 PRINTS PR00050 Cold shock protein signature 4 19 1.2E-19 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS13910 b880210af9ec2f9cb61c70ce6b1c9bf5 68 PIRSF PIRSF002599 1 67 8.7E-26 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 SMD11_RS13910 b880210af9ec2f9cb61c70ce6b1c9bf5 68 SUPERFAMILY SSF50249 1 64 1.11E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS13910 b880210af9ec2f9cb61c70ce6b1c9bf5 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 6.5E-31 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS13910 b880210af9ec2f9cb61c70ce6b1c9bf5 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 06-07-2017 IPR019844 Cold-shock conserved site SMD11_RS13910 b880210af9ec2f9cb61c70ce6b1c9bf5 68 SMART SM00357 3 66 1.4E-30 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 SMD11_RS13910 b880210af9ec2f9cb61c70ce6b1c9bf5 68 Gene3D G3DSA:2.40.50.140 1 65 1.4E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS33110 f2117e06dc05a56fdd9b54e1508c40f1 473 Pfam PF13699 Domain of unknown function (DUF4157) 139 203 7.8E-13 T 06-07-2017 IPR025295 Domain of unknown function DUF4157 SMD11_RS12685 71083a3da86d12635596f48db082356b 294 Pfam PF00171 Aldehyde dehydrogenase family 24 254 2.4E-40 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS12685 71083a3da86d12635596f48db082356b 294 SUPERFAMILY SSF53720 6 255 1.27E-44 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS12685 71083a3da86d12635596f48db082356b 294 Gene3D G3DSA:3.40.605.10 4 254 1.2E-54 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS01935 13387174661064c476f6c5d6d4c6fe07 479 SUPERFAMILY SSF52777 61 214 3.78E-18 T 06-07-2017 SMD11_RS01935 13387174661064c476f6c5d6d4c6fe07 479 SUPERFAMILY SSF52777 238 462 6.6E-16 T 06-07-2017 SMD11_RS01935 13387174661064c476f6c5d6d4c6fe07 479 Pfam PF00668 Condensation domain 67 336 2.4E-9 T 06-07-2017 IPR001242 Condensation domain SMD11_RS19965 9ae2b7ff4bb8c053f1b7b857b704d649 260 SMART SM00422 7 75 2.2E-13 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS19965 9ae2b7ff4bb8c053f1b7b857b704d649 260 Pfam PF13411 MerR HTH family regulatory protein 7 73 1.3E-18 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS19965 9ae2b7ff4bb8c053f1b7b857b704d649 260 SUPERFAMILY SSF46955 7 74 6.87E-17 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS19965 9ae2b7ff4bb8c053f1b7b857b704d649 260 Gene3D G3DSA:1.10.1660.10 7 78 2.6E-18 T 06-07-2017 SMD11_RS19965 9ae2b7ff4bb8c053f1b7b857b704d649 260 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 3.9E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS19965 9ae2b7ff4bb8c053f1b7b857b704d649 260 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 3.9E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS19965 9ae2b7ff4bb8c053f1b7b857b704d649 260 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 3.9E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS32425 942554aadbfb19778a14c6596ee2b24c 451 SUPERFAMILY SSF47384 203 283 1.53E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS32425 942554aadbfb19778a14c6596ee2b24c 451 Gene3D G3DSA:3.30.565.10 290 438 3.1E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS32425 942554aadbfb19778a14c6596ee2b24c 451 Gene3D G3DSA:1.10.287.130 210 283 6.2E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS32425 942554aadbfb19778a14c6596ee2b24c 451 SMART SM00388 220 288 2.2E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS32425 942554aadbfb19778a14c6596ee2b24c 451 Pfam PF00672 HAMP domain 147 216 1.8E-16 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS32425 942554aadbfb19778a14c6596ee2b24c 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 415 3.6E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS32425 942554aadbfb19778a14c6596ee2b24c 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 392 3.6E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS32425 942554aadbfb19778a14c6596ee2b24c 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 434 3.6E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS32425 942554aadbfb19778a14c6596ee2b24c 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 378 3.6E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS32425 942554aadbfb19778a14c6596ee2b24c 451 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 333 435 1.5E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS32425 942554aadbfb19778a14c6596ee2b24c 451 Pfam PF00512 His Kinase A (phospho-acceptor) domain 221 285 1.8E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS32425 942554aadbfb19778a14c6596ee2b24c 451 SMART SM00387 331 437 2.3E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS32425 942554aadbfb19778a14c6596ee2b24c 451 SMART SM00304 166 219 3.9E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS32425 942554aadbfb19778a14c6596ee2b24c 451 SUPERFAMILY SSF55874 287 438 4.45E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS32425 942554aadbfb19778a14c6596ee2b24c 451 SUPERFAMILY SSF158472 167 216 2.75E-6 T 06-07-2017 SMD11_RS00900 a2368951be60d2d913639c3c135f9a1f 163 Pfam PF11188 Protein of unknown function (DUF2975) 47 163 1.8E-26 T 06-07-2017 IPR021354 Protein of unknown function DUF2975 SMD11_RS18280 0d861bc444ae89101e05b0fa18232d39 473 PIRSF PIRSF000445 1 462 2.4E-130 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMD11_RS18280 0d861bc444ae89101e05b0fa18232d39 473 SUPERFAMILY SSF69742 1 158 5.36E-44 T 06-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMD11_RS18280 0d861bc444ae89101e05b0fa18232d39 473 SUPERFAMILY SSF51735 185 288 5.04E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18280 0d861bc444ae89101e05b0fa18232d39 473 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 446 25.476 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMD11_RS18280 0d861bc444ae89101e05b0fa18232d39 473 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 349 448 1.2E-20 T 06-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMD11_RS18280 0d861bc444ae89101e05b0fa18232d39 473 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 06-07-2017 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMD11_RS18280 0d861bc444ae89101e05b0fa18232d39 473 Gene3D G3DSA:3.40.50.720 185 336 1.1E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18280 0d861bc444ae89101e05b0fa18232d39 473 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 449 5.8E-107 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMD11_RS18280 0d861bc444ae89101e05b0fa18232d39 473 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 185 336 1.1E-19 T 06-07-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase SMD11_RS18280 0d861bc444ae89101e05b0fa18232d39 473 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 4.9E-44 T 06-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMD11_RS18280 0d861bc444ae89101e05b0fa18232d39 473 SUPERFAMILY SSF69075 347 449 1.44E-16 T 06-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 SMD11_RS11725 fb6730ee55221beb02c8080974f9f441 864 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 132 140 - T 06-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site SMD11_RS11725 fb6730ee55221beb02c8080974f9f441 864 SMART SM00487 1 204 2.2E-44 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS11725 fb6730ee55221beb02c8080974f9f441 864 Pfam PF00271 Helicase conserved C-terminal domain 212 321 3.0E-28 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS11725 fb6730ee55221beb02c8080974f9f441 864 Gene3D G3DSA:3.40.50.300 2 200 5.8E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11725 fb6730ee55221beb02c8080974f9f441 864 SMART SM00490 240 321 5.6E-32 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS11725 fb6730ee55221beb02c8080974f9f441 864 Gene3D G3DSA:3.40.50.300 201 353 1.8E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11725 fb6730ee55221beb02c8080974f9f441 864 SUPERFAMILY SSF52540 53 341 1.14E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11725 fb6730ee55221beb02c8080974f9f441 864 Pfam PF00270 DEAD/DEAH box helicase 2 172 1.2E-46 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD11_RS23225 a1dc2aae6ac60bdfc911ec581e3fe81f 338 Pfam PF00248 Aldo/keto reductase family 22 318 2.7E-70 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS23225 a1dc2aae6ac60bdfc911ec581e3fe81f 338 Gene3D G3DSA:3.20.20.100 6 328 6.5E-105 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS23225 a1dc2aae6ac60bdfc911ec581e3fe81f 338 SUPERFAMILY SSF51430 8 319 3.27E-93 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS04040 79086771cefadde8fb3c7c531baf6f92 416 SUPERFAMILY SSF103473 12 407 1.83E-43 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS04040 79086771cefadde8fb3c7c531baf6f92 416 Gene3D G3DSA:1.20.1250.20 204 392 3.5E-10 T 06-07-2017 SMD11_RS04040 79086771cefadde8fb3c7c531baf6f92 416 Pfam PF07690 Major Facilitator Superfamily 24 363 4.9E-29 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS04040 79086771cefadde8fb3c7c531baf6f92 416 Gene3D G3DSA:1.20.1250.20 12 188 2.7E-24 T 06-07-2017 SMD11_RS00675 22403ff4291fd55327f93e64b59c913e 362 Gene3D G3DSA:1.20.140.10 217 347 3.4E-19 T 06-07-2017 SMD11_RS00675 22403ff4291fd55327f93e64b59c913e 362 SUPERFAMILY SSF47203 216 350 8.38E-25 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS00675 22403ff4291fd55327f93e64b59c913e 362 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 218 322 5.8E-16 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS19675 7b8f83c81572225515977ffc379778b5 186 Pfam PF12802 MarR family 63 123 2.5E-11 T 06-07-2017 SMD11_RS19675 7b8f83c81572225515977ffc379778b5 186 Gene3D G3DSA:1.10.10.10 27 175 7.2E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19675 7b8f83c81572225515977ffc379778b5 186 SMART SM00347 57 160 3.8E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS19675 7b8f83c81572225515977ffc379778b5 186 SUPERFAMILY SSF46785 27 174 2.27E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19675 7b8f83c81572225515977ffc379778b5 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 135 3.3E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS19675 7b8f83c81572225515977ffc379778b5 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 3.3E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS19675 7b8f83c81572225515977ffc379778b5 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 150 170 3.3E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS19675 7b8f83c81572225515977ffc379778b5 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 115 3.3E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS32820 16b25ea049726a8206a37a65ed39166b 481 SUPERFAMILY SSF48557 9 465 2.21E-146 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 SMD11_RS32820 16b25ea049726a8206a37a65ed39166b 481 PRINTS PR00145 Argininosuccinate lyase family signature 140 162 1.1E-6 T 06-07-2017 SMD11_RS32820 16b25ea049726a8206a37a65ed39166b 481 PRINTS PR00145 Argininosuccinate lyase family signature 181 201 1.1E-6 T 06-07-2017 SMD11_RS32820 16b25ea049726a8206a37a65ed39166b 481 PRINTS PR00145 Argininosuccinate lyase family signature 323 339 1.1E-6 T 06-07-2017 SMD11_RS32820 16b25ea049726a8206a37a65ed39166b 481 Gene3D G3DSA:1.10.275.10 8 145 5.9E-54 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal SMD11_RS32820 16b25ea049726a8206a37a65ed39166b 481 Pfam PF00206 Lyase 18 348 2.0E-102 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal SMD11_RS32820 16b25ea049726a8206a37a65ed39166b 481 Gene3D G3DSA:1.20.200.10 146 408 1.3E-88 T 06-07-2017 SMD11_RS32820 16b25ea049726a8206a37a65ed39166b 481 Gene3D G3DSA:1.10.40.30 414 470 6.1E-21 T 06-07-2017 SMD11_RS32820 16b25ea049726a8206a37a65ed39166b 481 Pfam PF10415 Fumarase C C-terminus 414 466 5.3E-20 T 06-07-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD11_RS32820 16b25ea049726a8206a37a65ed39166b 481 ProSitePatterns PS00163 Fumarate lyases signature. 323 332 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 SMD11_RS32820 16b25ea049726a8206a37a65ed39166b 481 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 10 471 2.9E-209 T 06-07-2017 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 SMD11_RS32820 16b25ea049726a8206a37a65ed39166b 481 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 1.3E-30 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS32820 16b25ea049726a8206a37a65ed39166b 481 PRINTS PR00149 Fumarate lyase superfamily signature 323 339 1.3E-30 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS32820 16b25ea049726a8206a37a65ed39166b 481 PRINTS PR00149 Fumarate lyase superfamily signature 277 304 1.3E-30 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS32820 16b25ea049726a8206a37a65ed39166b 481 PRINTS PR00149 Fumarate lyase superfamily signature 186 204 1.3E-30 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 Pfam PF00400 WD domain, G-beta repeat 624 647 0.26 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 Pfam PF13360 PQQ-like domain 420 610 4.9E-5 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 Gene3D G3DSA:3.30.200.20 11 84 1.9E-13 T 06-07-2017 SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 Gene3D G3DSA:2.130.10.10 411 559 2.1E-23 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 Gene3D G3DSA:2.130.10.10 569 678 4.1E-23 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 SUPERFAMILY SSF50998 413 680 2.9E-41 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 SUPERFAMILY SSF56112 12 260 2.7E-63 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 Pfam PF00069 Protein kinase domain 15 256 2.7E-35 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 SMART SM00320 484 529 3.2 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 SMART SM00320 609 647 0.27 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 SMART SM00320 650 695 240.0 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 SMART SM00320 568 606 0.15 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 SMART SM00320 403 440 8.8 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 Gene3D G3DSA:1.10.510.10 85 256 5.8E-39 T 06-07-2017 SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 SMART SM00220 15 265 6.6E-42 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS19520 4cd6ffe5b893b0e5f633d9f0a7958fad 697 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS10460 17d0d628049034d2b4415bb67be8c743 157 Gene3D G3DSA:2.80.10.50 3 143 2.3E-30 T 06-07-2017 SMD11_RS10460 17d0d628049034d2b4415bb67be8c743 157 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 3 81 8.9E-21 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS10460 17d0d628049034d2b4415bb67be8c743 157 SUPERFAMILY SSF50370 2 143 2.65E-38 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS26435 679e06782f1ada981343cf2282d116d1 354 Gene3D G3DSA:3.20.20.80 153 295 4.7E-8 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS26435 679e06782f1ada981343cf2282d116d1 354 SUPERFAMILY SSF51445 121 293 3.16E-7 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS08935 517d6a0268610f26c82c6281b8b329c6 170 Gene3D G3DSA:2.60.120.10 34 152 5.8E-18 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS08935 517d6a0268610f26c82c6281b8b329c6 170 Pfam PF05995 Cysteine dioxygenase type I 32 154 1.2E-43 T 06-07-2017 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 SMD11_RS08935 517d6a0268610f26c82c6281b8b329c6 170 SUPERFAMILY SSF51182 12 156 3.68E-29 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS20655 773c1869f9d9b5b6534002301c2382b2 496 SMART SM00701 301 449 2.6E-57 T 06-07-2017 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 SMD11_RS20655 773c1869f9d9b5b6534002301c2382b2 496 Gene3D G3DSA:3.40.80.10 298 493 4.1E-52 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS20655 773c1869f9d9b5b6534002301c2382b2 496 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 324 476 1.5E-11 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS20655 773c1869f9d9b5b6534002301c2382b2 496 SUPERFAMILY SSF55846 301 488 1.44E-49 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS30460 d0e71ed53fa8b718bd672e769149dbe0 288 SUPERFAMILY SSF53955 86 288 5.91E-67 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS30460 d0e71ed53fa8b718bd672e769149dbe0 288 Gene3D G3DSA:1.10.530.10 87 144 9.8E-54 T 06-07-2017 SMD11_RS30460 d0e71ed53fa8b718bd672e769149dbe0 288 Gene3D G3DSA:1.10.530.10 208 288 9.8E-54 T 06-07-2017 SMD11_RS30460 d0e71ed53fa8b718bd672e769149dbe0 288 PIRSF PIRSF001060 1 288 1.5E-82 T 06-07-2017 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 SMD11_RS30460 d0e71ed53fa8b718bd672e769149dbe0 288 Pfam PF00182 Chitinase class I 88 288 3.0E-44 T 06-07-2017 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 SMD11_RS30460 d0e71ed53fa8b718bd672e769149dbe0 288 Gene3D G3DSA:3.30.20.10 153 207 2.7E-24 T 06-07-2017 SMD11_RS32865 0a681675bce8f8522b86f916337f44c6 410 Pfam PF13181 Tetratricopeptide repeat 148 180 0.17 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS32865 0a681675bce8f8522b86f916337f44c6 410 Gene3D G3DSA:1.25.40.10 100 376 3.4E-16 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS32865 0a681675bce8f8522b86f916337f44c6 410 SMART SM00530 10 64 2.2E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS32865 0a681675bce8f8522b86f916337f44c6 410 Gene3D G3DSA:1.10.260.40 5 69 7.6E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS32865 0a681675bce8f8522b86f916337f44c6 410 Pfam PF13560 Helix-turn-helix domain 7 62 5.2E-10 T 06-07-2017 SMD11_RS32865 0a681675bce8f8522b86f916337f44c6 410 SUPERFAMILY SSF48452 107 225 1.62E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS32865 0a681675bce8f8522b86f916337f44c6 410 SUPERFAMILY SSF47413 6 68 1.15E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS34300 403f862dca8f17f1d36592c5ff7ff143 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 74 9.5E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS34300 403f862dca8f17f1d36592c5ff7ff143 212 SUPERFAMILY SSF46689 15 94 5.49E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS34300 403f862dca8f17f1d36592c5ff7ff143 212 Gene3D G3DSA:1.10.357.10 17 203 4.8E-41 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS34300 403f862dca8f17f1d36592c5ff7ff143 212 SUPERFAMILY SSF48498 93 199 2.63E-14 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS34300 403f862dca8f17f1d36592c5ff7ff143 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 2.8E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS34300 403f862dca8f17f1d36592c5ff7ff143 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 2.8E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS03720 64f4c5ed5c5a0d4c23ec4271265cd4e3 411 Gene3D G3DSA:2.40.110.10 122 218 2.6E-33 T 06-07-2017 SMD11_RS03720 64f4c5ed5c5a0d4c23ec4271265cd4e3 411 SUPERFAMILY SSF47203 229 394 4.19E-11 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS03720 64f4c5ed5c5a0d4c23ec4271265cd4e3 411 SUPERFAMILY SSF56645 27 241 4.58E-63 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS03720 64f4c5ed5c5a0d4c23ec4271265cd4e3 411 Gene3D G3DSA:1.20.140.10 219 401 2.0E-22 T 06-07-2017 SMD11_RS03720 64f4c5ed5c5a0d4c23ec4271265cd4e3 411 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 392 1.1E-14 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS03720 64f4c5ed5c5a0d4c23ec4271265cd4e3 411 Gene3D G3DSA:1.10.540.10 24 120 1.7E-18 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS03720 64f4c5ed5c5a0d4c23ec4271265cd4e3 411 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 206 4.3E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS03720 64f4c5ed5c5a0d4c23ec4271265cd4e3 411 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 119 5.7E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS00630 f7d76deea277d658bcf0a2b9701421bd 111 Gene3D G3DSA:1.10.530.10 23 108 1.8E-9 T 06-07-2017 SMD11_RS00630 f7d76deea277d658bcf0a2b9701421bd 111 Pfam PF01464 Transglycosylase SLT domain 36 108 2.2E-8 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 SMD11_RS00630 f7d76deea277d658bcf0a2b9701421bd 111 SUPERFAMILY SSF53955 9 105 8.44E-15 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS14410 a088b473a4a2de94569ff6695f26e3e9 95 Pfam PF07210 Protein of unknown function (DUF1416) 2 95 2.3E-35 T 06-07-2017 IPR010814 Protein of unknown function DUF1416 SMD11_RS14410 a088b473a4a2de94569ff6695f26e3e9 95 Gene3D G3DSA:2.60.40.10 19 83 5.8E-5 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS14855 2a3ab2b4c8aeb054759668bfb51fbb7f 306 Gene3D G3DSA:3.40.50.720 19 181 1.9E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS14855 2a3ab2b4c8aeb054759668bfb51fbb7f 306 Gene3D G3DSA:1.10.1040.20 185 282 9.7E-31 T 06-07-2017 IPR018931 Domain of unknown function DUF2520 SMD11_RS14855 2a3ab2b4c8aeb054759668bfb51fbb7f 306 SUPERFAMILY SSF51735 21 183 4.16E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS14855 2a3ab2b4c8aeb054759668bfb51fbb7f 306 SUPERFAMILY SSF48179 185 284 3.74E-23 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS14855 2a3ab2b4c8aeb054759668bfb51fbb7f 306 Pfam PF10728 Domain of unknown function (DUF2520) 152 277 3.5E-37 T 06-07-2017 IPR018931 Domain of unknown function DUF2520 SMD11_RS14855 2a3ab2b4c8aeb054759668bfb51fbb7f 306 Pfam PF10727 Rossmann-like domain 11 135 8.1E-42 T 06-07-2017 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain SMD11_RS31050 2fdc225629d056dcfa40af5b03a9938c 262 Gene3D G3DSA:3.40.50.150 21 234 5.4E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS31050 2fdc225629d056dcfa40af5b03a9938c 262 Pfam PF13649 Methyltransferase domain 55 147 2.6E-14 T 06-07-2017 SMD11_RS31050 2fdc225629d056dcfa40af5b03a9938c 262 SUPERFAMILY SSF53335 23 244 3.53E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS31510 01b5ccfb595db255b5e7b4681a6b4bf7 239 Gene3D G3DSA:3.60.15.10 3 224 6.3E-26 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS31510 01b5ccfb595db255b5e7b4681a6b4bf7 239 SUPERFAMILY SSF56281 3 218 7.37E-22 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS00690 774492e42f9a579cbaedb6fac94fa9ef 211 SUPERFAMILY SSF46689 22 78 3.8E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS00690 774492e42f9a579cbaedb6fac94fa9ef 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 9.2E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00690 774492e42f9a579cbaedb6fac94fa9ef 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 9.2E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00690 774492e42f9a579cbaedb6fac94fa9ef 211 Gene3D G3DSA:1.10.357.10 76 209 7.7E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS00690 774492e42f9a579cbaedb6fac94fa9ef 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 78 1.6E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00690 774492e42f9a579cbaedb6fac94fa9ef 211 Gene3D G3DSA:1.10.10.60 23 75 4.5E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS12665 84d34241870828837a49dbb523eb05dc 555 Gene3D G3DSA:3.40.120.10 18 208 4.1E-60 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS12665 84d34241870828837a49dbb523eb05dc 555 SUPERFAMILY SSF53738 202 306 4.32E-24 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS12665 84d34241870828837a49dbb523eb05dc 555 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 140 154 8.5E-5 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS12665 84d34241870828837a49dbb523eb05dc 555 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 287 302 8.5E-5 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS12665 84d34241870828837a49dbb523eb05dc 555 SUPERFAMILY SSF53738 295 431 5.89E-24 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS12665 84d34241870828837a49dbb523eb05dc 555 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 501 527 7.7E-7 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS12665 84d34241870828837a49dbb523eb05dc 555 SUPERFAMILY SSF55957 433 533 4.06E-14 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS12665 84d34241870828837a49dbb523eb05dc 555 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 205 303 1.7E-26 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS12665 84d34241870828837a49dbb523eb05dc 555 Gene3D G3DSA:3.30.310.50 456 543 8.3E-19 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS12665 84d34241870828837a49dbb523eb05dc 555 Gene3D G3DSA:3.40.120.10 222 299 2.3E-23 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS12665 84d34241870828837a49dbb523eb05dc 555 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 45 183 6.6E-41 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS12665 84d34241870828837a49dbb523eb05dc 555 Gene3D G3DSA:3.40.120.10 300 434 9.5E-31 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS12665 84d34241870828837a49dbb523eb05dc 555 SUPERFAMILY SSF53738 35 208 2.79E-43 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS12665 84d34241870828837a49dbb523eb05dc 555 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 318 426 1.0E-14 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS12665 84d34241870828837a49dbb523eb05dc 555 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 141 150 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SMD11_RS07800 d3dec6f38b3b7858ff13adab0fb48e97 141 Pfam PF07366 SnoaL-like polyketide cyclase 12 129 1.2E-33 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain SMD11_RS07800 d3dec6f38b3b7858ff13adab0fb48e97 141 Gene3D G3DSA:3.10.450.50 7 137 8.4E-42 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS07800 d3dec6f38b3b7858ff13adab0fb48e97 141 SUPERFAMILY SSF54427 4 134 1.91E-41 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS17215 46a19a357335340d0bbfd2dd6f2be656 571 Pfam PF03793 PASTA domain 511 554 6.8E-7 T 06-07-2017 IPR005543 PASTA domain SMD11_RS17215 46a19a357335340d0bbfd2dd6f2be656 571 Pfam PF00069 Protein kinase domain 20 281 2.5E-49 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS17215 46a19a357335340d0bbfd2dd6f2be656 571 Gene3D G3DSA:1.10.510.10 90 283 3.2E-47 T 06-07-2017 SMD11_RS17215 46a19a357335340d0bbfd2dd6f2be656 571 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 26 49 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS17215 46a19a357335340d0bbfd2dd6f2be656 571 SMART SM00740 498 566 2.9E-4 T 06-07-2017 IPR005543 PASTA domain SMD11_RS17215 46a19a357335340d0bbfd2dd6f2be656 571 SUPERFAMILY SSF56112 18 355 1.48E-74 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS17215 46a19a357335340d0bbfd2dd6f2be656 571 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 147 159 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS17215 46a19a357335340d0bbfd2dd6f2be656 571 SMART SM00220 20 287 1.4E-64 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS17215 46a19a357335340d0bbfd2dd6f2be656 571 Gene3D G3DSA:3.30.200.20 16 89 7.6E-26 T 06-07-2017 SMD11_RS17405 47a6bcea78b8bf69f3b2536ec22d02de 392 SUPERFAMILY SSF54373 177 276 8.83E-11 T 06-07-2017 SMD11_RS17405 47a6bcea78b8bf69f3b2536ec22d02de 392 SUPERFAMILY SSF51905 3 172 2.33E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS17405 47a6bcea78b8bf69f3b2536ec22d02de 392 SUPERFAMILY SSF51905 270 375 2.33E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS17405 47a6bcea78b8bf69f3b2536ec22d02de 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 3.2E-15 T 06-07-2017 SMD11_RS17405 47a6bcea78b8bf69f3b2536ec22d02de 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 3.2E-15 T 06-07-2017 SMD11_RS17405 47a6bcea78b8bf69f3b2536ec22d02de 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 3.2E-15 T 06-07-2017 SMD11_RS17405 47a6bcea78b8bf69f3b2536ec22d02de 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 3.2E-15 T 06-07-2017 SMD11_RS17405 47a6bcea78b8bf69f3b2536ec22d02de 392 Gene3D G3DSA:3.50.50.60 4 178 1.1E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS17405 47a6bcea78b8bf69f3b2536ec22d02de 392 Gene3D G3DSA:3.50.50.60 270 354 1.1E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS17405 47a6bcea78b8bf69f3b2536ec22d02de 392 Pfam PF01494 FAD binding domain 280 342 5.7E-8 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS17405 47a6bcea78b8bf69f3b2536ec22d02de 392 Pfam PF01494 FAD binding domain 3 169 1.1E-10 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS10785 e87ca2f1940d60b5bcb4260e30ca1355 480 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 350 359 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD11_RS10785 e87ca2f1940d60b5bcb4260e30ca1355 480 Gene3D G3DSA:1.10.1140.10 362 477 7.1E-45 T 06-07-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD11_RS10785 e87ca2f1940d60b5bcb4260e30ca1355 480 Gene3D G3DSA:2.40.10.170 5 89 9.3E-31 T 06-07-2017 SMD11_RS10785 e87ca2f1940d60b5bcb4260e30ca1355 480 SUPERFAMILY SSF52540 92 364 1.1E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10785 e87ca2f1940d60b5bcb4260e30ca1355 480 Hamap MF_01347 ATP synthase subunit beta [atpB]. 9 477 54.32 T 06-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 SMD11_RS10785 e87ca2f1940d60b5bcb4260e30ca1355 480 Gene3D G3DSA:3.40.50.300 92 361 4.1E-103 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10785 e87ca2f1940d60b5bcb4260e30ca1355 480 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 11 477 1.5E-237 T 06-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 SMD11_RS10785 e87ca2f1940d60b5bcb4260e30ca1355 480 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 14 88 4.5E-22 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD11_RS10785 e87ca2f1940d60b5bcb4260e30ca1355 480 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 146 359 1.1E-64 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD11_RS10785 e87ca2f1940d60b5bcb4260e30ca1355 480 SUPERFAMILY SSF50615 10 89 2.41E-25 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD11_RS10785 e87ca2f1940d60b5bcb4260e30ca1355 480 SUPERFAMILY SSF47917 362 477 8.63E-46 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SMD11_RS10785 e87ca2f1940d60b5bcb4260e30ca1355 480 SMART SM00382 158 344 6.9E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS05305 1dd905ccbdd8e33c525062cc4dde9e7d 649 Pfam PF02780 Transketolase, C-terminal domain 505 616 1.4E-28 T 06-07-2017 IPR033248 Transketolase, C-terminal domain SMD11_RS05305 1dd905ccbdd8e33c525062cc4dde9e7d 649 Pfam PF02779 Transketolase, pyrimidine binding domain 318 480 5.2E-36 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS05305 1dd905ccbdd8e33c525062cc4dde9e7d 649 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS05305 1dd905ccbdd8e33c525062cc4dde9e7d 649 SMART SM00861 317 481 6.1E-51 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS05305 1dd905ccbdd8e33c525062cc4dde9e7d 649 SUPERFAMILY SSF52518 313 478 1.62E-50 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS05305 1dd905ccbdd8e33c525062cc4dde9e7d 649 Gene3D G3DSA:3.40.50.970 299 483 6.6E-53 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS05305 1dd905ccbdd8e33c525062cc4dde9e7d 649 ProSitePatterns PS00802 Transketolase signature 2. 423 439 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS05305 1dd905ccbdd8e33c525062cc4dde9e7d 649 Gene3D G3DSA:3.40.50.920 504 624 4.1E-31 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS05305 1dd905ccbdd8e33c525062cc4dde9e7d 649 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 280 3.3E-106 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS05305 1dd905ccbdd8e33c525062cc4dde9e7d 649 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 624 7.7E-183 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS05305 1dd905ccbdd8e33c525062cc4dde9e7d 649 Gene3D G3DSA:3.40.50.970 237 298 2.7E-52 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS05305 1dd905ccbdd8e33c525062cc4dde9e7d 649 Gene3D G3DSA:3.40.50.970 3 189 2.7E-52 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS05305 1dd905ccbdd8e33c525062cc4dde9e7d 649 SUPERFAMILY SSF52518 3 347 8.25E-71 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS05305 1dd905ccbdd8e33c525062cc4dde9e7d 649 SUPERFAMILY SSF52922 502 622 1.83E-27 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS05305 1dd905ccbdd8e33c525062cc4dde9e7d 649 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 625 40.703 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 SUPERFAMILY SSF48264 13 408 8.77E-96 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 PRINTS PR00385 P450 superfamily signature 357 368 2.3E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 PRINTS PR00385 P450 superfamily signature 348 357 2.3E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 PRINTS PR00385 P450 superfamily signature 282 293 2.3E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 PRINTS PR00385 P450 superfamily signature 247 264 2.3E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 PRINTS PR00359 B-class P450 signature 165 180 6.9E-54 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 PRINTS PR00359 B-class P450 signature 148 164 6.9E-54 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 PRINTS PR00359 B-class P450 signature 357 368 6.9E-54 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 PRINTS PR00359 B-class P450 signature 299 326 6.9E-54 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 PRINTS PR00359 B-class P450 signature 201 223 6.9E-54 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 PRINTS PR00359 B-class P450 signature 327 342 6.9E-54 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 PRINTS PR00359 B-class P450 signature 101 112 6.9E-54 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 PRINTS PR00359 B-class P450 signature 282 293 6.9E-54 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 PRINTS PR00359 B-class P450 signature 348 357 6.9E-54 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 350 359 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 Pfam PF00067 Cytochrome P450 191 377 6.4E-25 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS10020 245a82163812eb50daaef43ea26cf6fa 408 Gene3D G3DSA:1.10.630.10 17 408 2.7E-121 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS14295 8a4424db4e11f7b136b2e96263442736 461 SUPERFAMILY SSF47384 217 303 9.02E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS14295 8a4424db4e11f7b136b2e96263442736 461 SUPERFAMILY SSF158472 183 230 9.02E-8 T 06-07-2017 SMD11_RS14295 8a4424db4e11f7b136b2e96263442736 461 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 452 1.5E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14295 8a4424db4e11f7b136b2e96263442736 461 Gene3D G3DSA:3.30.565.10 314 456 3.5E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14295 8a4424db4e11f7b136b2e96263442736 461 Gene3D G3DSA:1.10.287.130 225 301 1.4E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS14295 8a4424db4e11f7b136b2e96263442736 461 Pfam PF00672 HAMP domain 161 228 2.4E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS14295 8a4424db4e11f7b136b2e96263442736 461 SMART SM00388 234 305 3.0E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS14295 8a4424db4e11f7b136b2e96263442736 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 394 1.0E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS14295 8a4424db4e11f7b136b2e96263442736 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 1.0E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS14295 8a4424db4e11f7b136b2e96263442736 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 1.0E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS14295 8a4424db4e11f7b136b2e96263442736 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 408 1.0E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS14295 8a4424db4e11f7b136b2e96263442736 461 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 304 1.0E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS14295 8a4424db4e11f7b136b2e96263442736 461 SMART SM00304 180 233 6.6E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS14295 8a4424db4e11f7b136b2e96263442736 461 SMART SM00387 347 455 5.0E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14295 8a4424db4e11f7b136b2e96263442736 461 SUPERFAMILY SSF55874 295 453 1.09E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS31640 a5cacc0d4a8fbe870351a65f6ecac41b 540 Gene3D G3DSA:3.40.50.1820 217 346 1.6E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS31640 a5cacc0d4a8fbe870351a65f6ecac41b 540 Gene3D G3DSA:3.40.50.1820 91 176 1.6E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS31640 a5cacc0d4a8fbe870351a65f6ecac41b 540 Gene3D G3DSA:3.40.50.1820 406 527 1.6E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS31640 a5cacc0d4a8fbe870351a65f6ecac41b 540 SUPERFAMILY SSF53474 114 177 2.47E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS31640 a5cacc0d4a8fbe870351a65f6ecac41b 540 SUPERFAMILY SSF53474 219 273 2.47E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS31640 a5cacc0d4a8fbe870351a65f6ecac41b 540 SUPERFAMILY SSF53474 380 527 2.47E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS31640 a5cacc0d4a8fbe870351a65f6ecac41b 540 Pfam PF00561 alpha/beta hydrolase fold 127 511 3.8E-27 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS07095 7765144a957077a903a528067ac6ad33 803 SMART SM01008 44 150 1.2E-47 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS07095 7765144a957077a903a528067ac6ad33 803 SUPERFAMILY SSF56003 142 800 2.09E-150 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS07095 7765144a957077a903a528067ac6ad33 803 Gene3D G3DSA:3.30.365.10 386 488 3.7E-54 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS07095 7765144a957077a903a528067ac6ad33 803 Gene3D G3DSA:3.30.365.10 661 800 3.7E-54 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS07095 7765144a957077a903a528067ac6ad33 803 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 181 745 5.5E-146 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS07095 7765144a957077a903a528067ac6ad33 803 Gene3D G3DSA:3.90.1170.50 29 138 1.1E-41 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS07095 7765144a957077a903a528067ac6ad33 803 SUPERFAMILY SSF54665 29 170 6.54E-44 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS07095 7765144a957077a903a528067ac6ad33 803 Gene3D G3DSA:3.30.365.10 489 633 1.7E-27 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS07095 7765144a957077a903a528067ac6ad33 803 TIGRFAM TIGR03196 pucD: xanthine dehydrogenase D subunit 31 800 7.1E-243 T 06-07-2017 IPR017609 Xanthine dehydrogenase D subunit KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 SMD11_RS07095 7765144a957077a903a528067ac6ad33 803 Gene3D G3DSA:3.30.365.10 203 307 3.4E-30 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS07095 7765144a957077a903a528067ac6ad33 803 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 44 150 2.5E-31 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS07095 7765144a957077a903a528067ac6ad33 803 Gene3D G3DSA:3.30.365.10 310 384 2.4E-42 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS07095 7765144a957077a903a528067ac6ad33 803 Gene3D G3DSA:3.30.365.10 139 202 2.4E-42 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS20880 9e5830f190b87927e1a84e1da22dcd79 388 SUPERFAMILY SSF53756 1 386 6.28E-55 T 06-07-2017 SMD11_RS20880 9e5830f190b87927e1a84e1da22dcd79 388 Pfam PF13439 Glycosyltransferase Family 4 1 175 8.6E-7 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 SMD11_RS20880 9e5830f190b87927e1a84e1da22dcd79 388 Pfam PF00534 Glycosyl transferases group 1 185 365 2.0E-28 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 SMD11_RS20880 9e5830f190b87927e1a84e1da22dcd79 388 Gene3D G3DSA:3.40.50.2000 186 365 1.1E-20 T 06-07-2017 SMD11_RS15940 e603f5803924831691d2918222261263 749 SMART SM00926 63 116 3.8E-8 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS15940 e603f5803924831691d2918222261263 749 Pfam PF01568 Molydopterin dinucleotide binding domain 633 740 7.7E-28 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMD11_RS15940 e603f5803924831691d2918222261263 749 Gene3D G3DSA:2.40.40.20 601 746 1.8E-53 T 06-07-2017 SMD11_RS15940 e603f5803924831691d2918222261263 749 Pfam PF00384 Molybdopterin oxidoreductase 119 540 5.0E-71 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS15940 e603f5803924831691d2918222261263 749 Gene3D G3DSA:2.20.25.90 65 115 1.0E-12 T 06-07-2017 SMD11_RS15940 e603f5803924831691d2918222261263 749 SUPERFAMILY SSF50692 595 745 5.2E-44 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain SMD11_RS15940 e603f5803924831691d2918222261263 749 Gene3D G3DSA:3.40.50.740 375 600 2.7E-77 T 06-07-2017 SMD11_RS15940 e603f5803924831691d2918222261263 749 Gene3D G3DSA:3.40.50.740 119 195 2.7E-77 T 06-07-2017 SMD11_RS15940 e603f5803924831691d2918222261263 749 Gene3D G3DSA:3.40.228.10 196 374 1.5E-47 T 06-07-2017 SMD11_RS15940 e603f5803924831691d2918222261263 749 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 65 110 9.7E-8 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS15940 e603f5803924831691d2918222261263 749 SUPERFAMILY SSF53706 64 619 1.57E-162 T 06-07-2017 SMD11_RS14055 28e3735f2ee06f410d7ece31f8fd7137 230 SUPERFAMILY SSF46894 162 229 1.67E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS14055 28e3735f2ee06f410d7ece31f8fd7137 230 Gene3D G3DSA:1.10.10.10 145 229 1.8E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14055 28e3735f2ee06f410d7ece31f8fd7137 230 ProSitePatterns PS00622 LuxR-type HTH domain signature. 183 210 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14055 28e3735f2ee06f410d7ece31f8fd7137 230 Gene3D G3DSA:3.40.50.2300 14 144 1.8E-34 T 06-07-2017 SMD11_RS14055 28e3735f2ee06f410d7ece31f8fd7137 230 Pfam PF00196 Bacterial regulatory proteins, luxR family 168 223 1.6E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14055 28e3735f2ee06f410d7ece31f8fd7137 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 199 1.7E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14055 28e3735f2ee06f410d7ece31f8fd7137 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 183 1.7E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14055 28e3735f2ee06f410d7ece31f8fd7137 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 199 211 1.7E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14055 28e3735f2ee06f410d7ece31f8fd7137 230 SMART SM00448 19 139 4.3E-33 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS14055 28e3735f2ee06f410d7ece31f8fd7137 230 SMART SM00421 166 223 2.9E-24 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14055 28e3735f2ee06f410d7ece31f8fd7137 230 SUPERFAMILY SSF52172 18 153 4.41E-31 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS14055 28e3735f2ee06f410d7ece31f8fd7137 230 Pfam PF00072 Response regulator receiver domain 21 140 1.3E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS13290 dd1fd476c9963095cbdaa1b6e2f42b89 821 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 65 819 0.0 T 06-07-2017 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 SMD11_RS13290 dd1fd476c9963095cbdaa1b6e2f42b89 821 Pfam PF00580 UvrD/REP helicase N-terminal domain 69 339 5.0E-78 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 SMD11_RS13290 dd1fd476c9963095cbdaa1b6e2f42b89 821 Gene3D G3DSA:3.40.50.300 65 169 4.9E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13290 dd1fd476c9963095cbdaa1b6e2f42b89 821 Gene3D G3DSA:3.40.50.300 248 353 4.9E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13290 dd1fd476c9963095cbdaa1b6e2f42b89 821 Gene3D G3DSA:3.40.50.300 626 717 9.4E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13290 dd1fd476c9963095cbdaa1b6e2f42b89 821 Gene3D G3DSA:3.40.50.300 354 456 9.4E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13290 dd1fd476c9963095cbdaa1b6e2f42b89 821 Gene3D G3DSA:1.10.10.160 173 247 5.0E-25 T 06-07-2017 IPR013986 DExx box DNA helicase domain SMD11_RS13290 dd1fd476c9963095cbdaa1b6e2f42b89 821 SUPERFAMILY SSF52540 65 716 1.97E-177 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13290 dd1fd476c9963095cbdaa1b6e2f42b89 821 Pfam PF13361 UvrD-like helicase C-terminal domain 345 688 6.1E-68 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMD11_RS13290 dd1fd476c9963095cbdaa1b6e2f42b89 821 Gene3D G3DSA:1.10.486.10 457 611 1.2E-47 T 06-07-2017 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 Pfam PF00403 Heavy-metal-associated domain 18 76 1.0E-11 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 Gene3D G3DSA:2.70.150.10 215 349 7.9E-28 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 SUPERFAMILY SSF56784 446 466 6.09E-52 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 SUPERFAMILY SSF56784 505 748 6.09E-52 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 450 456 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 671 683 1.2E-23 T 06-07-2017 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 573 584 1.2E-23 T 06-07-2017 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 648 667 1.2E-23 T 06-07-2017 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 595 605 1.2E-23 T 06-07-2017 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 448 462 1.2E-23 T 06-07-2017 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 298 312 1.2E-23 T 06-07-2017 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 Pfam PF00702 haloacid dehalogenase-like hydrolase 444 662 3.9E-44 T 06-07-2017 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 Gene3D G3DSA:3.40.50.1000 576 716 7.7E-51 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 Gene3D G3DSA:3.40.50.1000 419 463 7.7E-51 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 Gene3D G3DSA:3.40.1110.10 464 575 3.2E-22 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 SUPERFAMILY SSF81665 697 718 1.44E-11 T 06-07-2017 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 SUPERFAMILY SSF81665 218 252 1.44E-11 T 06-07-2017 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 SUPERFAMILY SSF81665 349 442 1.44E-11 T 06-07-2017 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 SUPERFAMILY SSF81653 254 348 7.32E-25 T 06-07-2017 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 ProSitePatterns PS01229 Hypothetical cof family signature 2. 648 670 - T 06-07-2017 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 167 750 1.1E-176 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 Gene3D G3DSA:3.30.70.100 12 79 4.3E-22 T 06-07-2017 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 SUPERFAMILY SSF55008 11 83 1.06E-18 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 Pfam PF00122 E1-E2 ATPase 221 439 1.1E-64 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 ProSitePatterns PS01047 Heavy-metal-associated domain. 20 48 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 223 729 1.8E-83 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 212 751 6.7E-151 T 06-07-2017 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 648 664 3.3E-7 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 679 704 3.3E-7 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS21835 52ff1e46e0419b75ea5fc68955b75cde 754 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 620 636 3.3E-7 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS26415 0eff80b803c226794720f375e374d81d 254 SMART SM00346 5 95 7.6E-34 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS26415 0eff80b803c226794720f375e374d81d 254 Gene3D G3DSA:1.10.10.10 3 74 2.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26415 0eff80b803c226794720f375e374d81d 254 Pfam PF01614 Bacterial transcriptional regulator 123 247 4.8E-31 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal SMD11_RS26415 0eff80b803c226794720f375e374d81d 254 Gene3D G3DSA:3.30.450.40 75 250 1.1E-42 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS26415 0eff80b803c226794720f375e374d81d 254 Pfam PF09339 IclR helix-turn-helix domain 7 58 2.9E-17 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS26415 0eff80b803c226794720f375e374d81d 254 SUPERFAMILY SSF55781 71 250 4.12E-36 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS26415 0eff80b803c226794720f375e374d81d 254 SUPERFAMILY SSF46785 5 77 4.63E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00160 54d25c4783ceb5f6b01792f9aba5c319 1078 SUPERFAMILY SSF52540 246 508 1.47E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00160 54d25c4783ceb5f6b01792f9aba5c319 1078 SUPERFAMILY SSF48452 766 872 9.3E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS00160 54d25c4783ceb5f6b01792f9aba5c319 1078 Pfam PF03704 Bacterial transcriptional activator domain 92 239 9.0E-23 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS00160 54d25c4783ceb5f6b01792f9aba5c319 1078 Gene3D G3DSA:3.40.50.300 265 386 4.8E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00160 54d25c4783ceb5f6b01792f9aba5c319 1078 Gene3D G3DSA:1.25.40.10 108 215 1.8E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS00160 54d25c4783ceb5f6b01792f9aba5c319 1078 Gene3D G3DSA:1.25.40.10 747 905 1.8E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS00160 54d25c4783ceb5f6b01792f9aba5c319 1078 SMART SM01043 92 239 6.1E-19 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS00160 54d25c4783ceb5f6b01792f9aba5c319 1078 SUPERFAMILY SSF48452 88 253 1.59E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS12440 109807378e519256109da99a113ded94 289 SUPERFAMILY SSF102588 4 287 7.06E-79 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD11_RS12440 109807378e519256109da99a113ded94 289 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 5 286 5.9E-151 T 06-07-2017 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 SMD11_RS12440 109807378e519256109da99a113ded94 289 Gene3D G3DSA:3.40.50.10320 3 287 3.3E-87 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD11_RS12440 109807378e519256109da99a113ded94 289 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 8 287 53.411 T 06-07-2017 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 SMD11_RS12440 109807378e519256109da99a113ded94 289 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 154 2.7E-26 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SMD11_RS26720 fc2628bc71678948a3795dbf8c039882 277 SMART SM00967 33 104 1.2E-14 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 SMD11_RS26720 fc2628bc71678948a3795dbf8c039882 277 SUPERFAMILY SSF55315 5 101 8.83E-21 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like SMD11_RS26720 fc2628bc71678948a3795dbf8c039882 277 Gene3D G3DSA:3.30.1330.30 5 100 4.2E-30 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like SMD11_RS26720 fc2628bc71678948a3795dbf8c039882 277 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 33 101 4.5E-11 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 SMD11_RS26720 fc2628bc71678948a3795dbf8c039882 277 SUPERFAMILY SSF75217 92 269 2.68E-40 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases SMD11_RS26720 fc2628bc71678948a3795dbf8c039882 277 Gene3D G3DSA:3.40.1280.10 111 266 4.0E-47 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMD11_RS26720 fc2628bc71678948a3795dbf8c039882 277 Pfam PF00588 SpoU rRNA Methylase family 115 259 7.6E-36 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SMD11_RS10600 58f6cd0011294411986624e9b9e5cc46 566 Pfam PF01642 Methylmalonyl-CoA mutase 29 558 2.0E-212 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS10600 58f6cd0011294411986624e9b9e5cc46 566 SUPERFAMILY SSF51703 9 560 9.68E-192 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS10600 58f6cd0011294411986624e9b9e5cc46 566 Gene3D G3DSA:3.20.20.240 28 560 5.6E-214 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS10600 58f6cd0011294411986624e9b9e5cc46 566 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 27 563 6.9E-200 T 06-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS28060 01ba246f422808149e128d0164e54542 828 Pfam PF00672 HAMP domain 316 400 7.1E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS28060 01ba246f422808149e128d0164e54542 828 Gene3D G3DSA:3.30.565.10 518 627 1.2E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS28060 01ba246f422808149e128d0164e54542 828 SMART SM00387 516 626 9.6E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS28060 01ba246f422808149e128d0164e54542 828 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 520 624 4.3E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS28060 01ba246f422808149e128d0164e54542 828 SUPERFAMILY SSF55874 502 624 1.57E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS28060 01ba246f422808149e128d0164e54542 828 Pfam PF08376 Nitrate and nitrite sensing 57 295 9.4E-33 T 06-07-2017 IPR013587 Nitrate/nitrite sensing protein SMD11_RS23975 7eced060c9654e18db2cb6f4c61d4d0d 377 Gene3D G3DSA:3.40.50.300 151 213 5.2E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23975 7eced060c9654e18db2cb6f4c61d4d0d 377 SUPERFAMILY SSF53795 150 228 2.17E-12 T 06-07-2017 SMD11_RS29550 154379ad2d1ed28e39be499237b6edc9 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 123 192 2.6E-6 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS29550 154379ad2d1ed28e39be499237b6edc9 218 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 140 156 1.3E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD11_RS29550 154379ad2d1ed28e39be499237b6edc9 218 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 158 178 1.3E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD11_RS29550 154379ad2d1ed28e39be499237b6edc9 218 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 13 24 1.3E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD11_RS29550 154379ad2d1ed28e39be499237b6edc9 218 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 131 196 3.3E-15 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD11_RS29550 154379ad2d1ed28e39be499237b6edc9 218 SUPERFAMILY SSF56784 14 204 2.02E-27 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS29550 154379ad2d1ed28e39be499237b6edc9 218 Gene3D G3DSA:3.40.50.1000 12 207 2.8E-32 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS17355 396910acf7fb0bb23a0dbb595c9ea634 404 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 6 87 8.7E-12 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS17355 396910acf7fb0bb23a0dbb595c9ea634 404 Gene3D G3DSA:2.80.10.50 7 156 2.0E-15 T 06-07-2017 SMD11_RS17355 396910acf7fb0bb23a0dbb595c9ea634 404 SUPERFAMILY SSF50370 6 154 3.01E-24 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS17355 396910acf7fb0bb23a0dbb595c9ea634 404 Gene3D G3DSA:2.110.10.10 333 381 2.0E-6 T 06-07-2017 IPR000585 Hemopexin-like domain SMD11_RS17355 396910acf7fb0bb23a0dbb595c9ea634 404 Gene3D G3DSA:2.110.10.10 219 281 2.0E-6 T 06-07-2017 IPR000585 Hemopexin-like domain SMD11_RS04020 ed27f2ed55f6fa89a3e58eea76a95e24 273 SUPERFAMILY SSF161098 89 268 6.38E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS04020 ed27f2ed55f6fa89a3e58eea76a95e24 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 269 8.0E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS16600 a87c1f2d036daa0299115f86f85790d0 166 Pfam PF13581 Histidine kinase-like ATPase domain 15 144 9.6E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16600 a87c1f2d036daa0299115f86f85790d0 166 SUPERFAMILY SSF55874 37 148 1.19E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16600 a87c1f2d036daa0299115f86f85790d0 166 Gene3D G3DSA:3.30.565.10 42 150 2.8E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS25885 901d2441651d50b18f1ccaf98fc5d2c1 416 SUPERFAMILY SSF53756 4 377 3.26E-66 T 06-07-2017 SMD11_RS25885 901d2441651d50b18f1ccaf98fc5d2c1 416 Pfam PF13439 Glycosyltransferase Family 4 13 191 5.6E-10 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 SMD11_RS25885 901d2441651d50b18f1ccaf98fc5d2c1 416 Gene3D G3DSA:3.40.50.2000 199 357 5.7E-22 T 06-07-2017 SMD11_RS25885 901d2441651d50b18f1ccaf98fc5d2c1 416 Pfam PF00534 Glycosyl transferases group 1 200 355 1.4E-36 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 SMD11_RS04135 a01c8046054ecfa760182d22c023706e 155 Gene3D G3DSA:2.40.260.10 9 131 5.3E-6 T 06-07-2017 IPR023365 Sortase domain SMD11_RS04135 a01c8046054ecfa760182d22c023706e 155 Pfam PF04203 Sortase family 9 149 6.5E-16 T 06-07-2017 IPR005754 Sortase family SMD11_RS04135 a01c8046054ecfa760182d22c023706e 155 SUPERFAMILY SSF63817 6 151 6.87E-15 T 06-07-2017 IPR023365 Sortase domain SMD11_RS34250 9f3d20bf579f30793d48f266142753fb 117 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 10 77 1.5E-20 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS34250 9f3d20bf579f30793d48f266142753fb 117 Gene3D G3DSA:1.10.260.40 36 75 8.8E-4 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS29235 77ec2447bac918e61d7c495dc8e08b26 140 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 16 139 26.685 T 06-07-2017 IPR023006 Uncharacterised protein family UPF0225 SMD11_RS29235 77ec2447bac918e61d7c495dc8e08b26 140 SUPERFAMILY SSF54427 41 138 4.82E-31 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS29235 77ec2447bac918e61d7c495dc8e08b26 140 Gene3D G3DSA:3.10.450.50 19 138 4.4E-39 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS28390 b717dda70adbc8247f6d0619ad3f2224 638 Pfam PF01642 Methylmalonyl-CoA mutase 53 542 1.6E-134 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS28390 b717dda70adbc8247f6d0619ad3f2224 638 Gene3D G3DSA:3.40.50.280 501 637 1.2E-51 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD11_RS28390 b717dda70adbc8247f6d0619ad3f2224 638 SUPERFAMILY SSF51703 10 538 2.88E-153 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS28390 b717dda70adbc8247f6d0619ad3f2224 638 Gene3D G3DSA:3.20.20.240 52 492 6.2E-136 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS28390 b717dda70adbc8247f6d0619ad3f2224 638 Gene3D G3DSA:1.10.196.20 8 33 6.5E-10 T 06-07-2017 IPR024067 Methylmalonyl-CoA mutase small subunit, N-terminal KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384 SMD11_RS28390 b717dda70adbc8247f6d0619ad3f2224 638 SUPERFAMILY SSF52242 477 637 8.48E-41 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD11_RS28390 b717dda70adbc8247f6d0619ad3f2224 638 TIGRFAM TIGR00642 mmCoA_mut_beta: methylmalonyl-CoA mutase, small subunit 10 638 2.1E-187 T 06-07-2017 IPR004608 Methylmalonyl-CoA mutase, beta chain GO:0004494|GO:0019652|GO:0031419 KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384 SMD11_RS10870 a09e03b94a96d180f884777ee85315da 304 Pfam PF00288 GHMP kinases N terminal domain 88 151 7.0E-12 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 SMD11_RS10870 a09e03b94a96d180f884777ee85315da 304 SUPERFAMILY SSF55060 173 289 2.16E-27 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain SMD11_RS10870 a09e03b94a96d180f884777ee85315da 304 PIRSF PIRSF000676 7 300 1.1E-83 T 06-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 SMD11_RS10870 a09e03b94a96d180f884777ee85315da 304 PRINTS PR00958 Homoserine kinase signature 18 33 6.0E-33 T 06-07-2017 SMD11_RS10870 a09e03b94a96d180f884777ee85315da 304 PRINTS PR00958 Homoserine kinase signature 254 269 6.0E-33 T 06-07-2017 SMD11_RS10870 a09e03b94a96d180f884777ee85315da 304 PRINTS PR00958 Homoserine kinase signature 138 151 6.0E-33 T 06-07-2017 SMD11_RS10870 a09e03b94a96d180f884777ee85315da 304 PRINTS PR00958 Homoserine kinase signature 177 194 6.0E-33 T 06-07-2017 SMD11_RS10870 a09e03b94a96d180f884777ee85315da 304 PRINTS PR00958 Homoserine kinase signature 101 116 6.0E-33 T 06-07-2017 SMD11_RS10870 a09e03b94a96d180f884777ee85315da 304 Gene3D G3DSA:3.30.230.10 10 159 1.8E-56 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS10870 a09e03b94a96d180f884777ee85315da 304 Gene3D G3DSA:3.30.70.890 171 291 7.2E-35 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain SMD11_RS10870 a09e03b94a96d180f884777ee85315da 304 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 94 105 - T 06-07-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 SMD11_RS10870 a09e03b94a96d180f884777ee85315da 304 SUPERFAMILY SSF54211 11 157 7.44E-29 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS10870 a09e03b94a96d180f884777ee85315da 304 TIGRFAM TIGR00191 thrB: homoserine kinase 11 281 2.5E-64 T 06-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 SMD11_RS10870 a09e03b94a96d180f884777ee85315da 304 Hamap MF_00384 Homoserine kinase [thrB]. 11 300 28.988 T 06-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 SMD11_RS10870 a09e03b94a96d180f884777ee85315da 304 Pfam PF08544 GHMP kinases C terminal 210 279 1.9E-5 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain SMD11_RS23005 98854f3f155b0b62f868a20ba3fcee57 249 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 31 82 2.8E-13 T 06-07-2017 IPR027805 Transposase, Helix-turn-helix domain SMD11_RS23005 98854f3f155b0b62f868a20ba3fcee57 249 Pfam PF13359 DDE superfamily endonuclease 98 245 1.1E-29 T 06-07-2017 IPR027806 Harbinger transposase-derived nuclease domain SMD11_RS31350 98854f3f155b0b62f868a20ba3fcee57 249 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 31 82 2.8E-13 T 06-07-2017 IPR027805 Transposase, Helix-turn-helix domain SMD11_RS31350 98854f3f155b0b62f868a20ba3fcee57 249 Pfam PF13359 DDE superfamily endonuclease 98 245 1.1E-29 T 06-07-2017 IPR027806 Harbinger transposase-derived nuclease domain SMD11_RS28985 3c25a116d08e81e3d335150a9bfa2d4a 395 SUPERFAMILY SSF47203 231 391 4.19E-25 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS28985 3c25a116d08e81e3d335150a9bfa2d4a 395 Gene3D G3DSA:1.20.140.10 221 392 6.3E-36 T 06-07-2017 SMD11_RS28985 3c25a116d08e81e3d335150a9bfa2d4a 395 SUPERFAMILY SSF56645 2 244 1.44E-66 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS28985 3c25a116d08e81e3d335150a9bfa2d4a 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 5.5E-25 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS28985 3c25a116d08e81e3d335150a9bfa2d4a 395 Gene3D G3DSA:1.10.540.10 4 119 8.6E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS28985 3c25a116d08e81e3d335150a9bfa2d4a 395 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 383 2.1E-29 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS28985 3c25a116d08e81e3d335150a9bfa2d4a 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 212 7.5E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS28985 3c25a116d08e81e3d335150a9bfa2d4a 395 Gene3D G3DSA:2.40.110.10 122 220 6.2E-34 T 06-07-2017 SMD11_RS24125 4e378691ba999746823dfbd3907a01b7 369 SUPERFAMILY SSF50156 278 366 3.29E-17 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS24125 4e378691ba999746823dfbd3907a01b7 369 Gene3D G3DSA:2.40.10.10 85 164 1.2E-24 T 06-07-2017 SMD11_RS24125 4e378691ba999746823dfbd3907a01b7 369 Gene3D G3DSA:2.30.42.10 280 368 8.8E-19 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS24125 4e378691ba999746823dfbd3907a01b7 369 SUPERFAMILY SSF50494 68 275 2.23E-50 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS24125 4e378691ba999746823dfbd3907a01b7 369 Pfam PF13365 Trypsin-like peptidase domain 91 235 1.6E-28 T 06-07-2017 SMD11_RS24125 4e378691ba999746823dfbd3907a01b7 369 Gene3D G3DSA:2.40.10.10 165 276 3.4E-36 T 06-07-2017 SMD11_RS24125 4e378691ba999746823dfbd3907a01b7 369 SMART SM00228 281 357 4.1E-7 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS24125 4e378691ba999746823dfbd3907a01b7 369 PRINTS PR00834 HtrA/DegQ protease family signature 315 327 2.1E-37 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS24125 4e378691ba999746823dfbd3907a01b7 369 PRINTS PR00834 HtrA/DegQ protease family signature 122 142 2.1E-37 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS24125 4e378691ba999746823dfbd3907a01b7 369 PRINTS PR00834 HtrA/DegQ protease family signature 228 245 2.1E-37 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS24125 4e378691ba999746823dfbd3907a01b7 369 PRINTS PR00834 HtrA/DegQ protease family signature 100 112 2.1E-37 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS24125 4e378691ba999746823dfbd3907a01b7 369 PRINTS PR00834 HtrA/DegQ protease family signature 164 188 2.1E-37 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS24125 4e378691ba999746823dfbd3907a01b7 369 PRINTS PR00834 HtrA/DegQ protease family signature 206 223 2.1E-37 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS24125 4e378691ba999746823dfbd3907a01b7 369 Pfam PF13180 PDZ domain 298 366 7.8E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS09520 48434149a3ca36ce9d8df35a8ed7e796 283 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 225 1.4E-106 T 06-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 SMD11_RS09520 48434149a3ca36ce9d8df35a8ed7e796 283 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 06-07-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 SMD11_RS09520 48434149a3ca36ce9d8df35a8ed7e796 283 Gene3D G3DSA:3.40.50.10490 159 245 4.4E-67 T 06-07-2017 SMD11_RS09520 48434149a3ca36ce9d8df35a8ed7e796 283 Gene3D G3DSA:3.40.50.10490 23 99 4.4E-67 T 06-07-2017 SMD11_RS09520 48434149a3ca36ce9d8df35a8ed7e796 283 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 226 41.881 T 06-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 SMD11_RS09520 48434149a3ca36ce9d8df35a8ed7e796 283 Gene3D G3DSA:1.10.287.610 100 153 1.7E-20 T 06-07-2017 SMD11_RS09520 48434149a3ca36ce9d8df35a8ed7e796 283 SUPERFAMILY SSF52313 6 232 7.72E-90 T 06-07-2017 IPR023591 Ribosomal protein S2, flavodoxin-like domain SMD11_RS09520 48434149a3ca36ce9d8df35a8ed7e796 283 PRINTS PR00395 Ribosomal protein S2 signature 197 211 3.2E-38 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS09520 48434149a3ca36ce9d8df35a8ed7e796 283 PRINTS PR00395 Ribosomal protein S2 signature 176 187 3.2E-38 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS09520 48434149a3ca36ce9d8df35a8ed7e796 283 PRINTS PR00395 Ribosomal protein S2 signature 37 46 3.2E-38 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS09520 48434149a3ca36ce9d8df35a8ed7e796 283 PRINTS PR00395 Ribosomal protein S2 signature 6 24 3.2E-38 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS09520 48434149a3ca36ce9d8df35a8ed7e796 283 PRINTS PR00395 Ribosomal protein S2 signature 159 176 3.2E-38 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS09520 48434149a3ca36ce9d8df35a8ed7e796 283 PRINTS PR00395 Ribosomal protein S2 signature 87 104 3.2E-38 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS09520 48434149a3ca36ce9d8df35a8ed7e796 283 Pfam PF00318 Ribosomal protein S2 9 225 1.3E-94 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS12420 0a0794c1483e908bfd8df287e1d55f37 491 SUPERFAMILY SSF103473 446 476 5.1E-29 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS12420 0a0794c1483e908bfd8df287e1d55f37 491 SUPERFAMILY SSF103473 189 398 5.1E-29 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS12420 0a0794c1483e908bfd8df287e1d55f37 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 56 78 2.1E-5 T 06-07-2017 SMD11_RS12420 0a0794c1483e908bfd8df287e1d55f37 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 117 141 2.1E-5 T 06-07-2017 SMD11_RS12420 0a0794c1483e908bfd8df287e1d55f37 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 379 398 2.1E-5 T 06-07-2017 SMD11_RS12420 0a0794c1483e908bfd8df287e1d55f37 491 Gene3D G3DSA:1.20.1250.20 2 172 7.6E-35 T 06-07-2017 SMD11_RS12420 0a0794c1483e908bfd8df287e1d55f37 491 Gene3D G3DSA:1.20.1250.20 237 399 1.4E-20 T 06-07-2017 SMD11_RS12420 0a0794c1483e908bfd8df287e1d55f37 491 Gene3D G3DSA:1.20.1250.20 447 476 1.4E-20 T 06-07-2017 SMD11_RS12420 0a0794c1483e908bfd8df287e1d55f37 491 SUPERFAMILY SSF103473 2 173 6.02E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS12420 0a0794c1483e908bfd8df287e1d55f37 491 Pfam PF07690 Major Facilitator Superfamily 3 388 2.7E-58 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS12420 0a0794c1483e908bfd8df287e1d55f37 491 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 6 401 6.7E-79 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS15110 77df6883bb55dcb3808a8e558a2f4666 366 Gene3D G3DSA:3.40.710.10 5 319 8.3E-55 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS15110 77df6883bb55dcb3808a8e558a2f4666 366 SUPERFAMILY SSF56601 14 326 2.73E-57 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS15110 77df6883bb55dcb3808a8e558a2f4666 366 Pfam PF00144 Beta-lactamase 18 316 8.9E-53 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 PRINTS PR00046 Major sigma-70 factor signature 259 270 1.6E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 PRINTS PR00046 Major sigma-70 factor signature 80 93 1.6E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 PRINTS PR00046 Major sigma-70 factor signature 227 239 1.6E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 PRINTS PR00046 Major sigma-70 factor signature 244 259 1.6E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 51 273 4.3E-94 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 Pfam PF04539 Sigma-70 region 3 137 202 9.3E-10 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 Gene3D G3DSA:1.10.10.10 124 179 9.0E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 SUPERFAMILY SSF88659 192 274 2.8E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 80 93 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 Pfam PF04542 Sigma-70 region 2 56 125 1.2E-17 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 SUPERFAMILY SSF88659 129 204 2.96E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 Gene3D G3DSA:1.10.601.10 48 123 3.4E-24 T 06-07-2017 SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 SUPERFAMILY SSF88946 28 125 2.49E-31 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 Gene3D G3DSA:1.10.10.10 215 274 3.0E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 Pfam PF04545 Sigma-70, region 4 223 272 1.4E-18 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16080 2fa4d6333f6aeceb0db54e0310401212 277 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 53 273 3.7E-36 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS21830 b0d419f141db698606e92a3b19f6e590 428 Gene3D G3DSA:1.10.230.10 282 374 2.4E-35 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 SMD11_RS21830 b0d419f141db698606e92a3b19f6e590 428 PRINTS PR00143 Citrate synthase signature 241 269 8.4E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS21830 b0d419f141db698606e92a3b19f6e590 428 PRINTS PR00143 Citrate synthase signature 360 376 8.4E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS21830 b0d419f141db698606e92a3b19f6e590 428 PRINTS PR00143 Citrate synthase signature 219 234 8.4E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS21830 b0d419f141db698606e92a3b19f6e590 428 PRINTS PR00143 Citrate synthase signature 297 317 8.4E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS21830 b0d419f141db698606e92a3b19f6e590 428 PRINTS PR00143 Citrate synthase signature 165 178 8.4E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS21830 b0d419f141db698606e92a3b19f6e590 428 PRINTS PR00143 Citrate synthase signature 380 394 8.4E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS21830 b0d419f141db698606e92a3b19f6e590 428 Pfam PF00285 Citrate synthase, C-terminal domain 46 412 1.5E-134 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS21830 b0d419f141db698606e92a3b19f6e590 428 ProSitePatterns PS00480 Citrate synthase signature. 304 316 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SMD11_RS21830 b0d419f141db698606e92a3b19f6e590 428 Gene3D G3DSA:1.10.580.10 52 281 1.6E-94 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SMD11_RS21830 b0d419f141db698606e92a3b19f6e590 428 PIRSF PIRSF001369 37 427 1.6E-152 T 06-07-2017 IPR024176 Citrate synthase, bacterial-type SMD11_RS21830 b0d419f141db698606e92a3b19f6e590 428 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 14 422 2.1E-180 T 06-07-2017 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 SMD11_RS21830 b0d419f141db698606e92a3b19f6e590 428 SUPERFAMILY SSF48256 3 422 6.02E-156 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 Pfam PF00330 Aconitase family (aconitate hydratase) 64 572 4.8E-181 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 SUPERFAMILY SSF52016 641 901 2.75E-85 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 Gene3D G3DSA:3.30.499.10 28 240 9.7E-79 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 Gene3D G3DSA:3.20.19.10 647 901 2.4E-76 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 Pfam PF00694 Aconitase C-terminal domain 702 831 7.3E-44 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 26 901 0.0 T 06-07-2017 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 ProSitePatterns PS01244 Aconitase family signature 2. 503 516 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 Gene3D G3DSA:3.40.1060.10 241 358 1.1E-35 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 PRINTS PR00415 Aconitase family signature 270 283 5.3E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 PRINTS PR00415 Aconitase family signature 141 154 5.3E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 PRINTS PR00415 Aconitase family signature 284 297 5.3E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 PRINTS PR00415 Aconitase family signature 165 173 5.3E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 PRINTS PR00415 Aconitase family signature 194 207 5.3E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 PRINTS PR00415 Aconitase family signature 503 516 5.3E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 PRINTS PR00415 Aconitase family signature 441 452 5.3E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 PRINTS PR00415 Aconitase family signature 208 223 5.3E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 PRINTS PR00415 Aconitase family signature 363 377 5.3E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 SUPERFAMILY SSF53732 4 637 6.15E-220 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 Gene3D G3DSA:3.30.499.10 359 384 5.1E-64 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 Gene3D G3DSA:3.30.499.10 429 585 5.1E-64 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS07595 115ddf9029ef5cb59623bacb08fe184a 904 ProSitePatterns PS00450 Aconitase family signature 1. 437 453 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 SMD11_RS10245 b47af8c2fba33136eb1ce9e4cb48fe52 346 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 243 331 6.6E-27 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS10245 b47af8c2fba33136eb1ce9e4cb48fe52 346 SMART SM00382 51 243 5.7E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS10245 b47af8c2fba33136eb1ce9e4cb48fe52 346 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 312 2.7E-17 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS10245 b47af8c2fba33136eb1ce9e4cb48fe52 346 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS10245 b47af8c2fba33136eb1ce9e4cb48fe52 346 Gene3D G3DSA:3.40.50.300 14 267 3.1E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10245 b47af8c2fba33136eb1ce9e4cb48fe52 346 SUPERFAMILY SSF52540 15 265 5.98E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10245 b47af8c2fba33136eb1ce9e4cb48fe52 346 Pfam PF00005 ABC transporter 43 193 1.6E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS03160 540b19d841e84df26d1e3ff5f8c80f65 407 SUPERFAMILY SSF53067 83 219 1.68E-13 T 06-07-2017 SMD11_RS03160 540b19d841e84df26d1e3ff5f8c80f65 407 Gene3D G3DSA:1.10.10.10 20 80 2.7E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03160 540b19d841e84df26d1e3ff5f8c80f65 407 Pfam PF00480 ROK family 96 392 8.7E-31 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS03160 540b19d841e84df26d1e3ff5f8c80f65 407 Gene3D G3DSA:3.30.420.40 82 233 2.2E-23 T 06-07-2017 SMD11_RS03160 540b19d841e84df26d1e3ff5f8c80f65 407 Gene3D G3DSA:3.30.420.40 234 381 2.1E-33 T 06-07-2017 SMD11_RS03160 540b19d841e84df26d1e3ff5f8c80f65 407 SUPERFAMILY SSF53067 227 402 8.84E-32 T 06-07-2017 SMD11_RS32830 9979bb65205041f9557f64bb0e126302 151 SMART SM00344 1 109 1.3E-41 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD11_RS32830 9979bb65205041f9557f64bb0e126302 151 Gene3D G3DSA:3.30.70.920 54 149 1.7E-24 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS32830 9979bb65205041f9557f64bb0e126302 151 Gene3D G3DSA:1.10.10.10 2 53 3.1E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32830 9979bb65205041f9557f64bb0e126302 151 SUPERFAMILY SSF46785 1 60 3.42E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32830 9979bb65205041f9557f64bb0e126302 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.2E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS32830 9979bb65205041f9557f64bb0e126302 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.2E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS32830 9979bb65205041f9557f64bb0e126302 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.2E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS32830 9979bb65205041f9557f64bb0e126302 151 SUPERFAMILY SSF54909 63 148 2.28E-17 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS32830 9979bb65205041f9557f64bb0e126302 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMD11_RS32830 9979bb65205041f9557f64bb0e126302 151 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 48 2.4E-19 T 06-07-2017 SMD11_RS32830 9979bb65205041f9557f64bb0e126302 151 Pfam PF01037 Lrp/AsnC ligand binding domain 67 140 1.7E-18 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS19505 7542ba93568f4f5124adb9214d477819 355 SUPERFAMILY SSF52540 13 170 1.83E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19505 7542ba93568f4f5124adb9214d477819 355 Gene3D G3DSA:2.40.30.10 250 345 6.2E-19 T 06-07-2017 SMD11_RS19505 7542ba93568f4f5124adb9214d477819 355 SUPERFAMILY SSF50447 154 247 4.57E-14 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS19505 7542ba93568f4f5124adb9214d477819 355 SUPERFAMILY SSF50465 252 351 1.15E-17 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SMD11_RS19505 7542ba93568f4f5124adb9214d477819 355 Gene3D G3DSA:3.40.50.300 60 162 1.7E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19505 7542ba93568f4f5124adb9214d477819 355 Pfam PF03143 Elongation factor Tu C-terminal domain 249 345 2.1E-11 T 06-07-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal SMD11_RS19505 7542ba93568f4f5124adb9214d477819 355 Pfam PF00009 Elongation factor Tu GTP binding domain 60 152 2.4E-9 T 06-07-2017 SMD11_RS19505 7542ba93568f4f5124adb9214d477819 355 Gene3D G3DSA:2.40.30.10 163 248 2.7E-15 T 06-07-2017 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 PRINTS PR00148 Enolase signature 46 60 5.5E-44 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 PRINTS PR00148 Enolase signature 320 331 5.5E-44 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 PRINTS PR00148 Enolase signature 343 357 5.5E-44 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 PRINTS PR00148 Enolase signature 372 389 5.5E-44 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 PRINTS PR00148 Enolase signature 170 183 5.5E-44 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 PRINTS PR00148 Enolase signature 116 132 5.5E-44 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 Gene3D G3DSA:3.30.390.10 12 134 5.1E-50 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 SMART SM01193 13 143 3.2E-83 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 ProSitePatterns PS00164 Enolase signature. 343 356 - T 06-07-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 Hamap MF_00318 Enolase [eno]. 11 420 43.169 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 SUPERFAMILY SSF54826 12 146 8.42E-51 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 Pfam PF03952 Enolase, N-terminal domain 13 143 1.5E-54 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 SMART SM01192 148 434 5.4E-205 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 SUPERFAMILY SSF51604 148 431 3.4E-120 T 06-07-2017 IPR029065 Enolase C-terminal domain-like SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 Gene3D G3DSA:3.20.20.120 137 433 2.2E-126 T 06-07-2017 IPR029065 Enolase C-terminal domain-like SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 Pfam PF00113 Enolase, C-terminal TIM barrel domain 149 433 1.6E-119 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 PIRSF PIRSF001400 9 433 4.5E-177 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS01155 212a8b1a05e03016364dfb472f8d2d73 435 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 13 432 1.2E-192 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS18730 73a3638b2ab3c4eb2ef1840c74f8d754 510 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 8 502 15.161 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 SMD11_RS18730 73a3638b2ab3c4eb2ef1840c74f8d754 510 Pfam PF00361 Proton-conducting membrane transporter 134 439 7.5E-53 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS17870 d196f3628f75389bd96912bdee62be5c 219 Gene3D G3DSA:3.40.50.2300 19 162 8.7E-35 T 06-07-2017 SMD11_RS17870 d196f3628f75389bd96912bdee62be5c 219 SUPERFAMILY SSF52172 19 147 2.7E-30 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS17870 d196f3628f75389bd96912bdee62be5c 219 Pfam PF00072 Response regulator receiver domain 22 133 2.6E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS17870 d196f3628f75389bd96912bdee62be5c 219 SMART SM00448 20 133 3.5E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS17870 d196f3628f75389bd96912bdee62be5c 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 213 3.7E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17870 d196f3628f75389bd96912bdee62be5c 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 3.9E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17870 d196f3628f75389bd96912bdee62be5c 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 3.9E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17870 d196f3628f75389bd96912bdee62be5c 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 3.9E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17870 d196f3628f75389bd96912bdee62be5c 219 SUPERFAMILY SSF46894 146 219 2.38E-15 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS17870 d196f3628f75389bd96912bdee62be5c 219 SMART SM00421 156 213 8.2E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS17870 d196f3628f75389bd96912bdee62be5c 219 Gene3D G3DSA:1.10.10.10 163 219 5.9E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27185 fefea4983c465a56bb43a85dd6b1b4d5 205 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 202 26.908 T 06-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 SMD11_RS27185 fefea4983c465a56bb43a85dd6b1b4d5 205 SUPERFAMILY SSF50249 1 62 1.03E-13 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS27185 fefea4983c465a56bb43a85dd6b1b4d5 205 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 178 2.1E-36 T 06-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 SMD11_RS27185 fefea4983c465a56bb43a85dd6b1b4d5 205 Pfam PF14520 Helix-hairpin-helix domain 71 129 4.9E-15 T 06-07-2017 SMD11_RS27185 fefea4983c465a56bb43a85dd6b1b4d5 205 Gene3D G3DSA:1.10.8.10 140 205 4.1E-12 T 06-07-2017 SMD11_RS27185 fefea4983c465a56bb43a85dd6b1b4d5 205 Pfam PF01330 RuvA N terminal domain 1 61 5.9E-18 T 06-07-2017 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 SMD11_RS27185 fefea4983c465a56bb43a85dd6b1b4d5 205 SUPERFAMILY SSF46929 148 203 4.45E-8 T 06-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 SMD11_RS27185 fefea4983c465a56bb43a85dd6b1b4d5 205 Gene3D G3DSA:2.40.50.140 1 64 1.2E-21 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS27185 fefea4983c465a56bb43a85dd6b1b4d5 205 SUPERFAMILY SSF47781 65 131 6.12E-19 T 06-07-2017 IPR010994 RuvA domain 2-like SMD11_RS27185 fefea4983c465a56bb43a85dd6b1b4d5 205 SMART SM00278 72 91 50.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SMD11_RS27185 fefea4983c465a56bb43a85dd6b1b4d5 205 SMART SM00278 107 126 0.05 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SMD11_RS27185 fefea4983c465a56bb43a85dd6b1b4d5 205 Pfam PF07499 RuvA, C-terminal domain 149 201 1.6E-10 T 06-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 SMD11_RS27185 fefea4983c465a56bb43a85dd6b1b4d5 205 Gene3D G3DSA:1.10.150.20 66 133 3.3E-26 T 06-07-2017 SMD11_RS05075 468f9656d39abdb457a09a7e28841080 267 PIRSF PIRSF006816 2 262 2.0E-60 T 06-07-2017 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 SMD11_RS05075 468f9656d39abdb457a09a7e28841080 267 Gene3D G3DSA:3.40.50.80 87 222 2.1E-30 T 06-07-2017 SMD11_RS05075 468f9656d39abdb457a09a7e28841080 267 PRINTS PR00410 Phenol hydroxylase reductase family signature 35 47 5.4E-7 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD11_RS05075 468f9656d39abdb457a09a7e28841080 267 PRINTS PR00410 Phenol hydroxylase reductase family signature 107 126 5.4E-7 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD11_RS05075 468f9656d39abdb457a09a7e28841080 267 PRINTS PR00410 Phenol hydroxylase reductase family signature 194 202 5.4E-7 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD11_RS05075 468f9656d39abdb457a09a7e28841080 267 Gene3D G3DSA:2.10.240.10 226 256 7.0E-7 T 06-07-2017 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain SMD11_RS05075 468f9656d39abdb457a09a7e28841080 267 Gene3D G3DSA:2.40.30.10 8 86 4.9E-14 T 06-07-2017 SMD11_RS05075 468f9656d39abdb457a09a7e28841080 267 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 133 142 3.6E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMD11_RS05075 468f9656d39abdb457a09a7e28841080 267 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 145 156 3.6E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMD11_RS05075 468f9656d39abdb457a09a7e28841080 267 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 107 126 3.6E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 SMD11_RS05075 468f9656d39abdb457a09a7e28841080 267 Pfam PF00175 Oxidoreductase NAD-binding domain 109 207 1.5E-14 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMD11_RS05075 468f9656d39abdb457a09a7e28841080 267 SUPERFAMILY SSF52343 98 241 1.1E-29 T 06-07-2017 SMD11_RS05075 468f9656d39abdb457a09a7e28841080 267 SUPERFAMILY SSF63380 5 96 5.2E-19 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD11_RS11990 26aed38fedf510bd703d96e483141456 334 SMART SM00382 40 240 2.0E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS11990 26aed38fedf510bd703d96e483141456 334 SUPERFAMILY SSF52540 40 319 1.46E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11990 26aed38fedf510bd703d96e483141456 334 Pfam PF00005 ABC transporter 32 190 3.1E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS11990 26aed38fedf510bd703d96e483141456 334 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 240 326 4.4E-28 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS11990 26aed38fedf510bd703d96e483141456 334 Gene3D G3DSA:3.40.50.300 11 264 1.4E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11990 26aed38fedf510bd703d96e483141456 334 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 306 5.8E-22 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS11990 26aed38fedf510bd703d96e483141456 334 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS28220 54c252c0c6ba7aa8c6804827cc03af3a 267 Pfam PF02517 CAAX protease self-immunity 159 248 5.7E-13 T 06-07-2017 IPR003675 CAAX amino terminal protease GO:0016020 SMD11_RS03785 5ef215bebd09438d28475a6430544297 349 Pfam PF03060 Nitronate monooxygenase 79 335 1.1E-62 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SMD11_RS03785 5ef215bebd09438d28475a6430544297 349 Gene3D G3DSA:3.20.20.70 2 331 9.8E-70 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS03785 5ef215bebd09438d28475a6430544297 349 SUPERFAMILY SSF51412 2 244 4.58E-59 T 06-07-2017 SMD11_RS03785 5ef215bebd09438d28475a6430544297 349 SUPERFAMILY SSF51412 304 343 4.58E-59 T 06-07-2017 SMD11_RS07475 9cb1370413ce09c662c4602408140dca 709 Pfam PF00378 Enoyl-CoA hydratase/isomerase 58 237 4.4E-18 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS07475 9cb1370413ce09c662c4602408140dca 709 Gene3D G3DSA:3.90.226.10 35 239 2.3E-34 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS07475 9cb1370413ce09c662c4602408140dca 709 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 340 520 6.3E-58 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS07475 9cb1370413ce09c662c4602408140dca 709 SUPERFAMILY SSF48179 634 699 1.36E-10 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS07475 9cb1370413ce09c662c4602408140dca 709 SUPERFAMILY SSF48179 522 615 2.38E-17 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS07475 9cb1370413ce09c662c4602408140dca 709 SUPERFAMILY SSF51735 338 522 2.2E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS07475 9cb1370413ce09c662c4602408140dca 709 Gene3D G3DSA:1.10.1040.10 526 611 6.8E-11 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS07475 9cb1370413ce09c662c4602408140dca 709 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 524 605 5.4E-11 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS07475 9cb1370413ce09c662c4602408140dca 709 SUPERFAMILY SSF52096 253 327 6.79E-34 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS07475 9cb1370413ce09c662c4602408140dca 709 SUPERFAMILY SSF52096 34 220 6.79E-34 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS07475 9cb1370413ce09c662c4602408140dca 709 Gene3D G3DSA:3.40.50.720 335 525 1.5E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32805 4384509974f8d47ec919e4925aa798ec 192 Gene3D G3DSA:3.40.630.30 9 175 3.9E-43 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS32805 4384509974f8d47ec919e4925aa798ec 192 Pfam PF13302 Acetyltransferase (GNAT) domain 11 150 3.2E-20 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS32805 4384509974f8d47ec919e4925aa798ec 192 SUPERFAMILY SSF55729 8 174 1.47E-38 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS00210 ac4c704ea9901d27caf4017e1a3bcde2 97 Pfam PF13586 Transposase DDE domain 3 96 9.1E-13 T 06-07-2017 IPR025668 Transposase DDE domain SMD11_RS19895 e3763d9d41a2699b3729678a5d49a8e3 753 Pfam PF12971 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain 62 141 4.2E-20 T 06-07-2017 IPR024240 Alpha-N-acetylglucosaminidase, N-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096|Reactome: R-HSA-2206282 SMD11_RS19895 e3763d9d41a2699b3729678a5d49a8e3 753 Pfam PF12972 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain 484 751 3.1E-70 T 06-07-2017 IPR024732 Alpha-N-acetylglucosaminidase, C-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096|Reactome: R-HSA-2206282 SMD11_RS19895 e3763d9d41a2699b3729678a5d49a8e3 753 Pfam PF05089 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain 156 476 1.3E-100 T 06-07-2017 IPR024733 Alpha-N-acetylglucosaminidase, tim-barrel domain KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096|Reactome: R-HSA-2206282 SMD11_RS01335 e3be005a4fdc3440a74ffc6ff9f54a2c 413 Gene3D G3DSA:3.40.50.2000 230 390 7.0E-46 T 06-07-2017 SMD11_RS01335 e3be005a4fdc3440a74ffc6ff9f54a2c 413 Pfam PF13579 Glycosyl transferase 4-like domain 30 178 1.5E-6 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 SMD11_RS01335 e3be005a4fdc3440a74ffc6ff9f54a2c 413 SUPERFAMILY SSF53756 14 408 2.37E-66 T 06-07-2017 SMD11_RS02110 bc8b874902219974abe1ffdf64971732 354 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 88 318 8.7E-44 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 SMD11_RS02110 bc8b874902219974abe1ffdf64971732 354 Pfam PF03193 Protein of unknown function, DUF258 92 262 5.7E-39 T 06-07-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 SMD11_RS02110 bc8b874902219974abe1ffdf64971732 354 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 36 326 30.687 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 SMD11_RS02110 bc8b874902219974abe1ffdf64971732 354 SUPERFAMILY SSF52540 112 323 1.39E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02110 bc8b874902219974abe1ffdf64971732 354 Gene3D G3DSA:1.10.40.50 266 331 2.5E-22 T 06-07-2017 SMD11_RS02110 bc8b874902219974abe1ffdf64971732 354 Gene3D G3DSA:3.40.50.300 113 261 1.6E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05990 193071a6afd1fe04f7a3b17f73babb42 134 Gene3D G3DSA:3.10.129.10 4 133 8.0E-32 T 06-07-2017 IPR029069 HotDog domain SMD11_RS05990 193071a6afd1fe04f7a3b17f73babb42 134 SUPERFAMILY SSF54637 4 132 1.12E-22 T 06-07-2017 IPR029069 HotDog domain SMD11_RS05990 193071a6afd1fe04f7a3b17f73babb42 134 Pfam PF03061 Thioesterase superfamily 18 101 1.2E-11 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 SMD11_RS07860 657d4018a48c1dd005a5fd652fab4bd5 96 Pfam PF00355 Rieske [2Fe-2S] domain 21 78 8.4E-9 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS07860 657d4018a48c1dd005a5fd652fab4bd5 96 Gene3D G3DSA:2.102.10.10 7 78 1.4E-16 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS07860 657d4018a48c1dd005a5fd652fab4bd5 96 SUPERFAMILY SSF50022 5 78 2.75E-15 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS14290 76e386444b835cc48d04ecd75ade1ead 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 235 5.1E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS14290 76e386444b835cc48d04ecd75ade1ead 243 SMART SM00862 160 235 1.9E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS14290 76e386444b835cc48d04ecd75ade1ead 243 Gene3D G3DSA:1.10.10.10 136 237 5.8E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14290 76e386444b835cc48d04ecd75ade1ead 243 SMART SM00448 11 122 3.7E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS14290 76e386444b835cc48d04ecd75ade1ead 243 Pfam PF00072 Response regulator receiver domain 13 123 1.3E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS14290 76e386444b835cc48d04ecd75ade1ead 243 SUPERFAMILY SSF52172 9 135 2.56E-43 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS14290 76e386444b835cc48d04ecd75ade1ead 243 SUPERFAMILY SSF46894 137 236 4.25E-31 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS14290 76e386444b835cc48d04ecd75ade1ead 243 Gene3D G3DSA:3.40.50.2300 9 133 8.2E-41 T 06-07-2017 SMD11_RS02985 0e8b9debc4cf897f8590c41a4713bfd8 884 SUPERFAMILY SSF52518 58 470 5.46E-114 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS02985 0e8b9debc4cf897f8590c41a4713bfd8 884 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 140 292 8.5E-10 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS02985 0e8b9debc4cf897f8590c41a4713bfd8 884 SUPERFAMILY SSF52922 706 882 2.79E-50 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS02985 0e8b9debc4cf897f8590c41a4713bfd8 884 Gene3D G3DSA:3.40.50.920 711 882 7.4E-65 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS02985 0e8b9debc4cf897f8590c41a4713bfd8 884 PIRSF PIRSF000156 1 884 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMD11_RS02985 0e8b9debc4cf897f8590c41a4713bfd8 884 Gene3D G3DSA:3.40.50.970 477 709 2.7E-109 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS02985 0e8b9debc4cf897f8590c41a4713bfd8 884 Gene3D G3DSA:3.40.50.970 58 471 7.8E-133 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS02985 0e8b9debc4cf897f8590c41a4713bfd8 884 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 7 883 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMD11_RS02985 0e8b9debc4cf897f8590c41a4713bfd8 884 SUPERFAMILY SSF52518 477 705 5.06E-87 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS28335 507ab5f628e4c938dd3ad565370177c7 137 Gene3D G3DSA:3.30.450.30 8 129 1.1E-23 T 06-07-2017 SMD11_RS28335 507ab5f628e4c938dd3ad565370177c7 137 SMART SM00960 9 102 1.5E-23 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS28335 507ab5f628e4c938dd3ad565370177c7 137 SUPERFAMILY SSF103196 7 131 2.56E-25 T 06-07-2017 SMD11_RS28335 507ab5f628e4c938dd3ad565370177c7 137 Pfam PF03259 Roadblock/LC7 domain 8 102 1.1E-22 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS20560 4e9635d5bd5ac3e8d8a359ed02f9af66 512 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 21 508 7.0E-165 T 06-07-2017 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 SMD11_RS20560 4e9635d5bd5ac3e8d8a359ed02f9af66 512 Pfam PF00854 POT family 109 467 9.1E-64 T 06-07-2017 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 SMD11_RS20560 4e9635d5bd5ac3e8d8a359ed02f9af66 512 SUPERFAMILY SSF103473 25 282 3.01E-20 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS20560 4e9635d5bd5ac3e8d8a359ed02f9af66 512 SUPERFAMILY SSF103473 233 502 5.23E-8 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS20560 4e9635d5bd5ac3e8d8a359ed02f9af66 512 Gene3D G3DSA:1.20.1250.20 81 218 4.1E-8 T 06-07-2017 SMD11_RS06625 9f20600f895b6dc225b8acd7af7dbdf5 466 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 6 459 2.0E-167 T 06-07-2017 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 SMD11_RS06625 9f20600f895b6dc225b8acd7af7dbdf5 466 SUPERFAMILY SSF51338 363 461 7.56E-34 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS06625 9f20600f895b6dc225b8acd7af7dbdf5 466 Gene3D G3DSA:2.30.40.10 381 459 1.4E-14 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS06625 9f20600f895b6dc225b8acd7af7dbdf5 466 Pfam PF01979 Amidohydrolase family 55 441 5.1E-26 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 SMD11_RS06625 9f20600f895b6dc225b8acd7af7dbdf5 466 Gene3D G3DSA:2.30.40.10 4 73 1.0E-24 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS06625 9f20600f895b6dc225b8acd7af7dbdf5 466 SUPERFAMILY SSF51338 2 71 3.02E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS06625 9f20600f895b6dc225b8acd7af7dbdf5 466 Gene3D G3DSA:3.20.20.140 74 380 4.9E-116 T 06-07-2017 SMD11_RS06625 9f20600f895b6dc225b8acd7af7dbdf5 466 SUPERFAMILY SSF51556 59 387 5.61E-105 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS21790 00ebc81835ac3136b570118c388153d8 477 Pfam PF05576 PS-10 peptidase S37 35 477 1.3E-202 T 06-07-2017 IPR008761 Peptidase S37, tripeptidyl aminopeptidase SMD11_RS21790 00ebc81835ac3136b570118c388153d8 477 SUPERFAMILY SSF53474 88 213 1.13E-11 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS21790 00ebc81835ac3136b570118c388153d8 477 SUPERFAMILY SSF53474 362 425 1.13E-11 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS21790 00ebc81835ac3136b570118c388153d8 477 Gene3D G3DSA:3.40.50.1820 307 390 1.5E-9 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS21790 00ebc81835ac3136b570118c388153d8 477 Gene3D G3DSA:3.40.50.1820 64 266 1.5E-9 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32870 54ac716f3112cf2e82103998cd61e5dd 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 9.4E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS32870 54ac716f3112cf2e82103998cd61e5dd 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 9.4E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS32870 54ac716f3112cf2e82103998cd61e5dd 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 9.4E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS32870 54ac716f3112cf2e82103998cd61e5dd 223 Pfam PF00072 Response regulator receiver domain 5 118 2.0E-5 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS32870 54ac716f3112cf2e82103998cd61e5dd 223 Gene3D G3DSA:1.10.10.10 162 219 1.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32870 54ac716f3112cf2e82103998cd61e5dd 223 SUPERFAMILY SSF46894 149 219 4.76E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS32870 54ac716f3112cf2e82103998cd61e5dd 223 SMART SM00421 156 213 2.7E-22 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS32870 54ac716f3112cf2e82103998cd61e5dd 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 213 1.2E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS32870 54ac716f3112cf2e82103998cd61e5dd 223 Gene3D G3DSA:3.40.50.2300 2 161 7.3E-15 T 06-07-2017 SMD11_RS32870 54ac716f3112cf2e82103998cd61e5dd 223 SUPERFAMILY SSF52172 2 139 3.92E-10 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS23710 1b2f5bdc72dcfcacc57ca7f67dd6a8ea 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 2.0E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS23710 1b2f5bdc72dcfcacc57ca7f67dd6a8ea 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 3.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS23710 1b2f5bdc72dcfcacc57ca7f67dd6a8ea 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 3.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS23710 1b2f5bdc72dcfcacc57ca7f67dd6a8ea 202 Pfam PF16859 Bacterial transcriptional repressor C-terminal 83 194 2.3E-27 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS23710 1b2f5bdc72dcfcacc57ca7f67dd6a8ea 202 SUPERFAMILY SSF46689 14 71 3.99E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS23710 1b2f5bdc72dcfcacc57ca7f67dd6a8ea 202 SUPERFAMILY SSF48498 84 201 1.34E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS23710 1b2f5bdc72dcfcacc57ca7f67dd6a8ea 202 Gene3D G3DSA:1.10.10.60 15 62 9.8E-24 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS23710 1b2f5bdc72dcfcacc57ca7f67dd6a8ea 202 Gene3D G3DSA:1.10.357.10 63 202 2.6E-43 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS31035 2a3a9afa9bcdc616799b5bd2de3b51f9 261 SUPERFAMILY SSF109854 13 143 2.56E-11 T 06-07-2017 SMD11_RS31035 2a3a9afa9bcdc616799b5bd2de3b51f9 261 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 14 137 1.2E-23 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD11_RS31035 2a3a9afa9bcdc616799b5bd2de3b51f9 261 Pfam PF07398 MDMPI C-terminal domain 150 254 1.3E-13 T 06-07-2017 IPR010872 MDMPI C-terminal SMD11_RS31035 2a3a9afa9bcdc616799b5bd2de3b51f9 261 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 16 235 7.4E-30 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD11_RS08890 6bae0b2f4b0b0cebb55f96d30562fef4 497 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 4 447 68.189 T 06-07-2017 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 SMD11_RS08890 6bae0b2f4b0b0cebb55f96d30562fef4 497 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 5 442 7.2E-153 T 06-07-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 SMD11_RS08890 6bae0b2f4b0b0cebb55f96d30562fef4 497 Gene3D G3DSA:3.80.30.20 150 381 2.5E-84 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe SMD11_RS08890 6bae0b2f4b0b0cebb55f96d30562fef4 497 SUPERFAMILY SSF102114 136 375 3.14E-58 T 06-07-2017 SMD11_RS08890 6bae0b2f4b0b0cebb55f96d30562fef4 497 SMART SM00729 150 369 1.3E-57 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD11_RS08890 6bae0b2f4b0b0cebb55f96d30562fef4 497 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 6 443 4.2E-147 T 06-07-2017 SMD11_RS08890 6bae0b2f4b0b0cebb55f96d30562fef4 497 Pfam PF04055 Radical SAM superfamily 154 324 1.0E-29 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS08890 6bae0b2f4b0b0cebb55f96d30562fef4 497 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 154 174 - T 06-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 SMD11_RS08890 6bae0b2f4b0b0cebb55f96d30562fef4 497 Pfam PF00919 Uncharacterized protein family UPF0004 7 107 1.1E-26 T 06-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 SMD11_RS02685 5c10a16d87ab4e9a35b67212b9a7cd2d 431 SUPERFAMILY SSF53092 23 165 2.41E-23 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal SMD11_RS02685 5c10a16d87ab4e9a35b67212b9a7cd2d 431 Gene3D G3DSA:3.40.350.10 19 139 6.2E-27 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SMD11_RS02685 5c10a16d87ab4e9a35b67212b9a7cd2d 431 SMART SM01011 17 178 4.4E-31 T 06-07-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 SMD11_RS02685 5c10a16d87ab4e9a35b67212b9a7cd2d 431 Pfam PF00557 Metallopeptidase family M24 179 404 2.4E-46 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS02685 5c10a16d87ab4e9a35b67212b9a7cd2d 431 SUPERFAMILY SSF55920 166 425 1.44E-56 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS02685 5c10a16d87ab4e9a35b67212b9a7cd2d 431 Gene3D G3DSA:3.90.230.10 164 425 7.0E-59 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS02685 5c10a16d87ab4e9a35b67212b9a7cd2d 431 Pfam PF05195 Aminopeptidase P, N-terminal domain 23 135 1.6E-18 T 06-07-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 SMD11_RS33255 ec8ecb350315b6e8833a12dd52854f8c 217 SUPERFAMILY SSF56784 4 204 8.08E-19 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS33255 ec8ecb350315b6e8833a12dd52854f8c 217 Gene3D G3DSA:3.40.50.1000 1 208 9.8E-16 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS01985 36c09c93881491f7c99eef83fdaaf23b 129 SMART SM00422 1 69 5.2E-17 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS01985 36c09c93881491f7c99eef83fdaaf23b 129 SUPERFAMILY SSF46955 1 117 3.26E-24 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS01985 36c09c93881491f7c99eef83fdaaf23b 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.9E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS01985 36c09c93881491f7c99eef83fdaaf23b 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 5.9E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS01985 36c09c93881491f7c99eef83fdaaf23b 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.9E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS01985 36c09c93881491f7c99eef83fdaaf23b 129 Pfam PF13411 MerR HTH family regulatory protein 1 67 1.1E-16 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS01985 36c09c93881491f7c99eef83fdaaf23b 129 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS01985 36c09c93881491f7c99eef83fdaaf23b 129 Gene3D G3DSA:1.10.1660.10 1 119 1.6E-26 T 06-07-2017 SMD11_RS06305 90bdb922755b3c82b336653fe95def8c 116 Gene3D G3DSA:3.10.180.10 2 109 5.5E-15 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS06305 90bdb922755b3c82b336653fe95def8c 116 SUPERFAMILY SSF54593 9 109 2.48E-12 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS31765 b0a2cd0d486665e2f9798d0d126a6889 680 Pfam PF08532 Beta-galactosidase trimerisation domain 464 539 5.2E-6 T 06-07-2017 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD11_RS31765 b0a2cd0d486665e2f9798d0d126a6889 680 Gene3D G3DSA:3.40.50.880 464 528 1.7E-5 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS31765 b0a2cd0d486665e2f9798d0d126a6889 680 SUPERFAMILY SSF51445 218 347 3.94E-11 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS31765 b0a2cd0d486665e2f9798d0d126a6889 680 SUPERFAMILY SSF51445 73 182 3.94E-11 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS31765 b0a2cd0d486665e2f9798d0d126a6889 680 SUPERFAMILY SSF52317 460 530 2.44E-6 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 469 2.3E-166 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 PRINTS PR01050 Pyruvate kinase family signature 214 240 6.2E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 PRINTS PR01050 Pyruvate kinase family signature 241 265 6.2E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 PRINTS PR01050 Pyruvate kinase family signature 184 198 6.2E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 PRINTS PR01050 Pyruvate kinase family signature 59 75 6.2E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 PRINTS PR01050 Pyruvate kinase family signature 291 309 6.2E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 PRINTS PR01050 Pyruvate kinase family signature 266 290 6.2E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 PRINTS PR01050 Pyruvate kinase family signature 310 326 6.2E-63 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 Gene3D G3DSA:3.20.20.60 167 323 1.2E-104 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 Gene3D G3DSA:3.20.20.60 2 72 1.2E-104 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 Pfam PF00224 Pyruvate kinase, barrel domain 1 337 9.9E-127 T 06-07-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 Gene3D G3DSA:2.40.33.10 73 166 5.5E-31 T 06-07-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 SUPERFAMILY SSF50800 71 164 2.79E-27 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 468 1.7E-28 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 SUPERFAMILY SSF51621 1 74 7.33E-97 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 SUPERFAMILY SSF51621 154 337 7.33E-97 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 06-07-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 Gene3D G3DSA:3.40.1380.20 324 468 5.0E-43 T 06-07-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS10570 5071b9e3534bb8016d3e767ab2ef7c66 474 SUPERFAMILY SSF52935 320 470 7.85E-39 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SMD11_RS14620 89c0d272314450dd7a0a02461d5248dd 501 Pfam PF00069 Protein kinase domain 9 262 5.9E-54 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS14620 89c0d272314450dd7a0a02461d5248dd 501 Gene3D G3DSA:3.30.200.20 5 87 1.9E-24 T 06-07-2017 SMD11_RS14620 89c0d272314450dd7a0a02461d5248dd 501 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 15 38 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS14620 89c0d272314450dd7a0a02461d5248dd 501 SMART SM00220 9 265 2.0E-70 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS14620 89c0d272314450dd7a0a02461d5248dd 501 SUPERFAMILY SSF56112 4 326 5.06E-87 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS14620 89c0d272314450dd7a0a02461d5248dd 501 Gene3D G3DSA:1.10.510.10 92 283 2.8E-55 T 06-07-2017 SMD11_RS14620 89c0d272314450dd7a0a02461d5248dd 501 Gene3D G3DSA:1.10.510.10 437 463 2.8E-55 T 06-07-2017 SMD11_RS14620 89c0d272314450dd7a0a02461d5248dd 501 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 127 139 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 32 700 41.092 T 06-07-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 SUPERFAMILY SSF56784 367 420 1.32E-38 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 SUPERFAMILY SSF56784 455 579 1.32E-38 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 SUPERFAMILY SSF56784 308 332 1.32E-38 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 32 696 0.0 T 06-07-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 Pfam PF00702 haloacid dehalogenase-like hydrolase 317 550 1.8E-32 T 06-07-2017 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 483 493 4.5E-25 T 06-07-2017 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 559 571 4.5E-25 T 06-07-2017 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 320 334 4.5E-25 T 06-07-2017 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 169 183 4.5E-25 T 06-07-2017 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 536 555 4.5E-25 T 06-07-2017 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 Gene3D G3DSA:3.40.50.1000 464 583 3.8E-37 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 Gene3D G3DSA:3.40.1110.10 331 463 1.5E-49 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 322 328 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 SUPERFAMILY SSF81653 127 222 2.75E-21 T 06-07-2017 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 Gene3D G3DSA:2.70.150.10 59 223 7.0E-25 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 SUPERFAMILY SSF81665 56 121 7.32E-12 T 06-07-2017 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 SUPERFAMILY SSF81665 223 314 7.32E-12 T 06-07-2017 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 90 358 2.0E-32 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 391 619 6.0E-42 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS08505 a668fd5a562cda1cfa8f27dd8bd91c68 703 Pfam PF00122 E1-E2 ATPase 90 311 1.1E-42 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS20360 f4c0d8e5f7478f0c5e96fc42cb31f2b8 506 Pfam PF03055 Retinal pigment epithelial membrane protein 40 500 1.5E-100 T 06-07-2017 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 SMD11_RS04075 ba38199a1c8a54dd2736fea7e1ef6ba1 249 SUPERFAMILY SSF81301 8 58 2.04E-7 T 06-07-2017 SMD11_RS04075 ba38199a1c8a54dd2736fea7e1ef6ba1 249 Pfam PF01909 Nucleotidyltransferase domain 13 50 7.6E-5 T 06-07-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 SMD11_RS04075 ba38199a1c8a54dd2736fea7e1ef6ba1 249 Gene3D G3DSA:3.30.460.10 7 94 1.2E-8 T 06-07-2017 SMD11_RS12550 c68d3d1bbdc9be202cb3ae3b843d738a 424 Gene3D G3DSA:2.40.440.10 261 392 7.0E-20 T 06-07-2017 SMD11_RS12550 c68d3d1bbdc9be202cb3ae3b843d738a 424 Pfam PF03734 L,D-transpeptidase catalytic domain 259 367 1.6E-13 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMD11_RS12550 c68d3d1bbdc9be202cb3ae3b843d738a 424 Pfam PF13205 Bacterial Ig-like domain 159 252 5.7E-7 T 06-07-2017 IPR032812 SbsA, Ig-like domain SMD11_RS12550 c68d3d1bbdc9be202cb3ae3b843d738a 424 SUPERFAMILY SSF141523 261 392 3.92E-23 T 06-07-2017 SMD11_RS00265 d7a5868bf44d23d8b98c85ec5d0e576b 293 Pfam PF02353 Mycolic acid cyclopropane synthetase 77 156 8.0E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS00265 d7a5868bf44d23d8b98c85ec5d0e576b 293 Gene3D G3DSA:3.40.50.150 22 260 9.3E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS00265 d7a5868bf44d23d8b98c85ec5d0e576b 293 SUPERFAMILY SSF53335 22 264 1.48E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS30050 18ea271fb820240fd36efb2b9f1afa2a 234 SUPERFAMILY SSF51182 99 234 4.07E-32 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS30050 18ea271fb820240fd36efb2b9f1afa2a 234 Pfam PF01381 Helix-turn-helix 60 113 8.3E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS30050 18ea271fb820240fd36efb2b9f1afa2a 234 SUPERFAMILY SSF47413 56 119 2.48E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS30050 18ea271fb820240fd36efb2b9f1afa2a 234 Pfam PF07883 Cupin domain 159 227 3.8E-20 T 06-07-2017 IPR013096 Cupin 2, conserved barrel SMD11_RS30050 18ea271fb820240fd36efb2b9f1afa2a 234 Gene3D G3DSA:1.10.260.40 56 109 1.5E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS30050 18ea271fb820240fd36efb2b9f1afa2a 234 Gene3D G3DSA:2.60.120.10 110 232 2.0E-28 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS30050 18ea271fb820240fd36efb2b9f1afa2a 234 SMART SM00530 59 114 2.6E-14 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS32615 42b93fe6bca641d721838980ddba9fb3 350 Gene3D G3DSA:3.40.50.720 168 314 1.3E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32615 42b93fe6bca641d721838980ddba9fb3 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 93 6.1E-11 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS32615 42b93fe6bca641d721838980ddba9fb3 350 SMART SM00829 15 347 3.8E-8 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS32615 42b93fe6bca641d721838980ddba9fb3 350 Gene3D G3DSA:3.90.180.10 10 167 1.7E-32 T 06-07-2017 IPR011032 GroES-like SMD11_RS32615 42b93fe6bca641d721838980ddba9fb3 350 SUPERFAMILY SSF51735 119 294 1.55E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32615 42b93fe6bca641d721838980ddba9fb3 350 Pfam PF13602 Zinc-binding dehydrogenase 221 347 6.0E-11 T 06-07-2017 SMD11_RS32615 42b93fe6bca641d721838980ddba9fb3 350 SUPERFAMILY SSF50129 19 146 8.98E-29 T 06-07-2017 IPR011032 GroES-like SMD11_RS28995 87cb1240681a3a0fba2477ab2f8a2839 440 Pfam PF12051 Protein of unknown function (DUF3533) 21 394 1.7E-51 T 06-07-2017 IPR022703 Domain of unknown function DUF3533 SMD11_RS28995 87cb1240681a3a0fba2477ab2f8a2839 440 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 21 170 2.4E-31 T 06-07-2017 IPR017500 Phage infection protein, YhgE, N-terminal SMD11_RS24690 74e5d07a5f7987c6cd62c90293068b6e 213 PIRSF PIRSF000495 5 213 1.7E-64 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 SMD11_RS24690 74e5d07a5f7987c6cd62c90293068b6e 213 Pfam PF00117 Glutamine amidotransferase class-I 9 206 6.5E-18 T 06-07-2017 IPR017926 Glutamine amidotransferase SMD11_RS24690 74e5d07a5f7987c6cd62c90293068b6e 213 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 7 211 1.8E-61 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 SMD11_RS24690 74e5d07a5f7987c6cd62c90293068b6e 213 SUPERFAMILY SSF52317 5 211 4.88E-54 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS24690 74e5d07a5f7987c6cd62c90293068b6e 213 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 6 212 31.011 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 SMD11_RS24690 74e5d07a5f7987c6cd62c90293068b6e 213 Gene3D G3DSA:3.40.50.880 4 211 1.3E-74 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS31320 bd3a25556335c7ab8fa7ba74622e91a5 285 Pfam PF00583 Acetyltransferase (GNAT) family 52 120 1.9E-4 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS31320 bd3a25556335c7ab8fa7ba74622e91a5 285 SUPERFAMILY SSF55729 7 264 1.3E-42 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS31320 bd3a25556335c7ab8fa7ba74622e91a5 285 Gene3D G3DSA:3.40.630.30 143 201 9.2E-7 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS31320 bd3a25556335c7ab8fa7ba74622e91a5 285 Gene3D G3DSA:3.40.630.30 6 127 1.7E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS27960 5da520628a3b649dfd4535bb09fd2de6 591 Pfam PF03098 Animal haem peroxidase 56 549 2.9E-101 T 06-07-2017 IPR019791 Haem peroxidase, animal SMD11_RS27960 5da520628a3b649dfd4535bb09fd2de6 591 PRINTS PR00457 Animal haem peroxidase signature 277 303 1.1E-5 T 06-07-2017 IPR019791 Haem peroxidase, animal SMD11_RS27960 5da520628a3b649dfd4535bb09fd2de6 591 PRINTS PR00457 Animal haem peroxidase signature 252 272 1.1E-5 T 06-07-2017 IPR019791 Haem peroxidase, animal SMD11_RS27960 5da520628a3b649dfd4535bb09fd2de6 591 SUPERFAMILY SSF48113 331 550 1.88E-103 T 06-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 SMD11_RS27960 5da520628a3b649dfd4535bb09fd2de6 591 SUPERFAMILY SSF48113 54 302 1.88E-103 T 06-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 SMD11_RS27960 5da520628a3b649dfd4535bb09fd2de6 591 Gene3D G3DSA:1.10.640.10 177 548 8.6E-88 T 06-07-2017 IPR019791 Haem peroxidase, animal SMD11_RS27960 5da520628a3b649dfd4535bb09fd2de6 591 Gene3D G3DSA:1.10.640.10 11 139 8.6E-88 T 06-07-2017 IPR019791 Haem peroxidase, animal SMD11_RS17640 ff8f5a46d83a8494b8a9a68126d9ece3 59 Pfam PF04149 Domain of unknown function (DUF397) 4 55 1.2E-12 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS06255 1396dc8d3da185c550cabb6ff5595441 402 Gene3D G3DSA:3.40.640.10 46 265 5.5E-19 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS06255 1396dc8d3da185c550cabb6ff5595441 402 Pfam PF00155 Aminotransferase class I and II 58 313 1.1E-8 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS06255 1396dc8d3da185c550cabb6ff5595441 402 SUPERFAMILY SSF53383 17 360 7.25E-34 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS23025 6955a7b9f9db57d4ec05153ca058090c 161 SUPERFAMILY SSF55729 11 145 5.49E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS23025 6955a7b9f9db57d4ec05153ca058090c 161 Pfam PF00583 Acetyltransferase (GNAT) family 54 130 1.3E-7 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS23025 6955a7b9f9db57d4ec05153ca058090c 161 Gene3D G3DSA:3.40.630.30 12 141 6.9E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS17325 e363656b05a38568805ec2c455a65fac 719 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 348 554 3.4E-44 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS17325 e363656b05a38568805ec2c455a65fac 719 Pfam PF13185 GAF domain 152 290 1.4E-10 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS17325 e363656b05a38568805ec2c455a65fac 719 SMART SM00331 318 554 9.5E-33 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS17325 e363656b05a38568805ec2c455a65fac 719 SMART SM00065 137 300 0.008 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS17325 e363656b05a38568805ec2c455a65fac 719 SUPERFAMILY SSF55781 154 293 1.42E-16 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS17325 e363656b05a38568805ec2c455a65fac 719 SUPERFAMILY SSF81606 334 552 6.28E-8 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS17325 e363656b05a38568805ec2c455a65fac 719 Gene3D G3DSA:3.30.450.40 135 293 5.2E-17 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS17325 e363656b05a38568805ec2c455a65fac 719 Gene3D G3DSA:3.30.450.20 2 112 5.0E-8 T 06-07-2017 SMD11_RS08525 9ff5ad56610b1356d3d32717c7342dcb 170 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 10 152 30.536 T 06-07-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 SMD11_RS08525 9ff5ad56610b1356d3d32717c7342dcb 170 TIGRFAM TIGR00576 dut: dUTP diphosphatase 13 151 2.4E-49 T 06-07-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 SMD11_RS08525 9ff5ad56610b1356d3d32717c7342dcb 170 Pfam PF00692 dUTPase 21 151 7.8E-31 T 06-07-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 SMD11_RS08525 9ff5ad56610b1356d3d32717c7342dcb 170 Gene3D G3DSA:2.70.40.10 11 151 1.8E-51 T 06-07-2017 IPR029054 dUTPase-like SMD11_RS08525 9ff5ad56610b1356d3d32717c7342dcb 170 SUPERFAMILY SSF51283 10 151 7.2E-43 T 06-07-2017 IPR029054 dUTPase-like SMD11_RS04085 c1cfa5138fd18396239df43e3653b621 327 Pfam PF14518 Iron-containing redox enzyme 129 304 9.2E-41 T 06-07-2017 IPR028201 PqqC-like protein SMD11_RS04085 c1cfa5138fd18396239df43e3653b621 327 SUPERFAMILY SSF48613 125 283 2.67E-7 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS04085 c1cfa5138fd18396239df43e3653b621 327 Gene3D G3DSA:1.20.910.10 99 320 1.5E-52 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS04085 c1cfa5138fd18396239df43e3653b621 327 SMART SM01236 161 266 8.0E-30 T 06-07-2017 SMD11_RS21875 73d83a8ccd456f43e8abcf1f1dfae960 340 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 128 1.2E-21 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD11_RS21875 73d83a8ccd456f43e8abcf1f1dfae960 340 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 140 241 2.9E-5 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD11_RS21875 73d83a8ccd456f43e8abcf1f1dfae960 340 SUPERFAMILY SSF55347 136 297 4.97E-16 T 06-07-2017 SMD11_RS21875 73d83a8ccd456f43e8abcf1f1dfae960 340 SUPERFAMILY SSF51735 4 157 4.81E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS21875 73d83a8ccd456f43e8abcf1f1dfae960 340 Gene3D G3DSA:3.30.360.10 145 330 3.6E-34 T 06-07-2017 SMD11_RS21875 73d83a8ccd456f43e8abcf1f1dfae960 340 Hamap MF_01671 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase [iolG]. 5 339 49.785 T 06-07-2017 IPR023794 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase GO:0019310|GO:0050112|GO:0055114 KEGG: 00521+1.1.1.18|KEGG: 00562+1.1.1.18|MetaCyc: PWY-5940|MetaCyc: PWY-7237|MetaCyc: PWY-7241 SMD11_RS21875 73d83a8ccd456f43e8abcf1f1dfae960 340 Gene3D G3DSA:3.40.50.720 3 144 8.5E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32810 da744a6b66ca30d30574f21eb3714048 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 59 1.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS32810 da744a6b66ca30d30574f21eb3714048 207 SUPERFAMILY SSF46689 3 75 3.24E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS32810 da744a6b66ca30d30574f21eb3714048 207 SUPERFAMILY SSF48498 80 192 1.37E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS32810 da744a6b66ca30d30574f21eb3714048 207 Pfam PF13977 Bacterial transcriptional repressor 82 193 3.9E-21 T 06-07-2017 SMD11_RS32810 da744a6b66ca30d30574f21eb3714048 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 58 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD11_RS32810 da744a6b66ca30d30574f21eb3714048 207 Gene3D G3DSA:1.10.357.10 4 201 3.9E-39 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS28745 3e564be8a869ff9d93bfe45cacb2ef3d 337 SMART SM00116 285 333 0.0096 T 06-07-2017 IPR000644 CBS domain SMD11_RS28745 3e564be8a869ff9d93bfe45cacb2ef3d 337 SMART SM00116 225 273 1.9 T 06-07-2017 IPR000644 CBS domain SMD11_RS28745 3e564be8a869ff9d93bfe45cacb2ef3d 337 Gene3D G3DSA:3.10.580.10 222 332 3.8E-17 T 06-07-2017 SMD11_RS28745 3e564be8a869ff9d93bfe45cacb2ef3d 337 Pfam PF00571 CBS domain 238 271 6.3E-4 T 06-07-2017 IPR000644 CBS domain SMD11_RS28745 3e564be8a869ff9d93bfe45cacb2ef3d 337 Pfam PF00571 CBS domain 284 333 2.2E-8 T 06-07-2017 IPR000644 CBS domain SMD11_RS28745 3e564be8a869ff9d93bfe45cacb2ef3d 337 Pfam PF01595 Domain of unknown function DUF21 8 199 2.9E-41 T 06-07-2017 IPR002550 Domain of unknown function DUF21 SMD11_RS28745 3e564be8a869ff9d93bfe45cacb2ef3d 337 SUPERFAMILY SSF54631 205 334 9.67E-24 T 06-07-2017 SMD11_RS27055 dc88e505981aa1c08186ab89f031c7e8 281 Gene3D G3DSA:3.40.630.30 21 110 2.5E-10 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS27055 dc88e505981aa1c08186ab89f031c7e8 281 SUPERFAMILY SSF55729 128 273 3.26E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS27055 dc88e505981aa1c08186ab89f031c7e8 281 Pfam PF00583 Acetyltransferase (GNAT) family 189 270 1.2E-14 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS27055 dc88e505981aa1c08186ab89f031c7e8 281 Pfam PF00583 Acetyltransferase (GNAT) family 28 104 3.9E-5 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS27055 dc88e505981aa1c08186ab89f031c7e8 281 Gene3D G3DSA:3.40.630.30 128 273 5.9E-26 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS27055 dc88e505981aa1c08186ab89f031c7e8 281 SUPERFAMILY SSF55729 17 109 2.3E-10 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS07865 03be2650175684ce52d2bf96acc0de8e 281 SUPERFAMILY SSF48613 84 273 1.61E-11 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS07865 03be2650175684ce52d2bf96acc0de8e 281 Pfam PF14518 Iron-containing redox enzyme 93 261 1.4E-28 T 06-07-2017 IPR028201 PqqC-like protein SMD11_RS07865 03be2650175684ce52d2bf96acc0de8e 281 SMART SM01236 125 230 6.4E-23 T 06-07-2017 SMD11_RS07865 03be2650175684ce52d2bf96acc0de8e 281 Gene3D G3DSA:1.20.910.10 63 272 1.1E-28 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS08315 2b75030a297606d62449786be33ada25 362 Gene3D G3DSA:1.10.260.40 157 211 7.0E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS08315 2b75030a297606d62449786be33ada25 362 SMART SM00530 163 218 2.6E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS08315 2b75030a297606d62449786be33ada25 362 SUPERFAMILY SSF47413 156 213 1.1E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS08315 2b75030a297606d62449786be33ada25 362 Pfam PF13560 Helix-turn-helix domain 161 215 3.1E-10 T 06-07-2017 SMD11_RS23555 5f6b2f15e434c3f081e269b7e55ed063 491 Pfam PF01433 Peptidase family M1 339 382 2.9E-18 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS23555 5f6b2f15e434c3f081e269b7e55ed063 491 Pfam PF01433 Peptidase family M1 74 308 3.4E-17 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS23555 5f6b2f15e434c3f081e269b7e55ed063 491 SUPERFAMILY SSF55486 268 488 2.49E-52 T 06-07-2017 SMD11_RS23555 5f6b2f15e434c3f081e269b7e55ed063 491 Gene3D G3DSA:1.10.390.10 354 489 1.6E-23 T 06-07-2017 SMD11_RS23555 5f6b2f15e434c3f081e269b7e55ed063 491 SUPERFAMILY SSF63737 59 259 4.71E-35 T 06-07-2017 SMD11_RS23555 5f6b2f15e434c3f081e269b7e55ed063 491 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 359 371 2.9E-12 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS23555 5f6b2f15e434c3f081e269b7e55ed063 491 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 195 210 2.9E-12 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS23555 5f6b2f15e434c3f081e269b7e55ed063 491 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 242 257 2.9E-12 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS23555 5f6b2f15e434c3f081e269b7e55ed063 491 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 340 355 2.9E-12 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS24130 abe8433e407d3e1eee8f8c426c3e735b 247 Pfam PF08241 Methyltransferase domain 34 134 8.2E-18 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS24130 abe8433e407d3e1eee8f8c426c3e735b 247 Gene3D G3DSA:3.40.50.150 19 153 7.4E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS24130 abe8433e407d3e1eee8f8c426c3e735b 247 SUPERFAMILY SSF53335 15 200 9.95E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS24580 5078ee6d9b01312ea5e55d71463a4bc9 313 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 139 153 - T 06-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS24580 5078ee6d9b01312ea5e55d71463a4bc9 313 Pfam PF00849 RNA pseudouridylate synthase 93 247 3.4E-31 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS24580 5078ee6d9b01312ea5e55d71463a4bc9 313 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 308 2.4E-86 T 06-07-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS24580 5078ee6d9b01312ea5e55d71463a4bc9 313 SUPERFAMILY SSF55120 82 309 5.12E-70 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS24580 5078ee6d9b01312ea5e55d71463a4bc9 313 SUPERFAMILY SSF55174 19 69 9.62E-6 T 06-07-2017 SMD11_RS24580 5078ee6d9b01312ea5e55d71463a4bc9 313 Gene3D G3DSA:3.10.290.10 19 58 7.5E-7 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 SMD11_RS08970 be9bad5d7aeb80f733256f79c11d1009 1588 SUPERFAMILY SSF52540 261 316 9.49E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08970 be9bad5d7aeb80f733256f79c11d1009 1588 SUPERFAMILY SSF52540 347 425 9.49E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08970 be9bad5d7aeb80f733256f79c11d1009 1588 SUPERFAMILY SSF52540 49 225 9.49E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08970 be9bad5d7aeb80f733256f79c11d1009 1588 SMART SM00382 52 403 0.0055 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS08970 be9bad5d7aeb80f733256f79c11d1009 1588 Gene3D G3DSA:3.40.50.300 283 445 1.8E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08970 be9bad5d7aeb80f733256f79c11d1009 1588 Pfam PF00270 DEAD/DEAH box helicase 40 223 8.1E-26 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD11_RS08970 be9bad5d7aeb80f733256f79c11d1009 1588 Pfam PF08494 DEAD/H associated 683 892 7.7E-78 T 06-07-2017 IPR013701 DEAD/H associated GO:0005524|GO:0016818 SMD11_RS08970 be9bad5d7aeb80f733256f79c11d1009 1588 Pfam PF00271 Helicase conserved C-terminal domain 292 416 2.5E-11 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS08970 be9bad5d7aeb80f733256f79c11d1009 1588 SMART SM00490 304 416 3.9E-13 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS08970 be9bad5d7aeb80f733256f79c11d1009 1588 SMART SM00487 35 254 1.1E-35 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS08970 be9bad5d7aeb80f733256f79c11d1009 1588 Gene3D G3DSA:3.40.50.300 25 229 1.9E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 SUPERFAMILY SSF51905 156 322 2.82E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 337 438 5.9E-20 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 Gene3D G3DSA:3.50.50.60 121 321 1.6E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.7E-16 T 06-07-2017 SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 284 291 2.7E-16 T 06-07-2017 SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 242 256 2.7E-16 T 06-07-2017 SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 2.7E-16 T 06-07-2017 SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 SUPERFAMILY SSF51905 4 201 5.25E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 SUPERFAMILY SSF55424 330 450 2.06E-32 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 Gene3D G3DSA:3.50.50.60 2 120 5.7E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 3.4E-18 T 06-07-2017 SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 3.4E-18 T 06-07-2017 SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 257 3.4E-18 T 06-07-2017 SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.4E-18 T 06-07-2017 SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 Gene3D G3DSA:3.30.390.30 342 451 1.7E-37 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD11_RS07400 704874b17a988c054bc6f2d1efb0104d 460 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 314 5.8E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02710 114829e5ddce8cffd535f36057dbe25c 326 Gene3D G3DSA:3.40.50.300 7 255 9.4E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02710 114829e5ddce8cffd535f36057dbe25c 326 Pfam PF00005 ABC transporter 32 181 1.1E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS02710 114829e5ddce8cffd535f36057dbe25c 326 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS02710 114829e5ddce8cffd535f36057dbe25c 326 SMART SM00382 40 239 6.0E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS02710 114829e5ddce8cffd535f36057dbe25c 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 322 2.3E-24 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS02710 114829e5ddce8cffd535f36057dbe25c 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 300 4.8E-16 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS02710 114829e5ddce8cffd535f36057dbe25c 326 SUPERFAMILY SSF52540 8 253 1.65E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01070 06796ae683ed72fe7f1386027f0e8f26 310 Gene3D G3DSA:3.10.450.50 185 298 2.1E-11 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS01070 06796ae683ed72fe7f1386027f0e8f26 310 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 176 7.5E-14 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS01070 06796ae683ed72fe7f1386027f0e8f26 310 Gene3D G3DSA:1.10.10.10 118 177 1.8E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01070 06796ae683ed72fe7f1386027f0e8f26 310 SUPERFAMILY SSF88659 118 176 1.18E-8 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS01070 06796ae683ed72fe7f1386027f0e8f26 310 Pfam PF08281 Sigma-70, region 4 125 175 1.2E-8 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS01070 06796ae683ed72fe7f1386027f0e8f26 310 Pfam PF04542 Sigma-70 region 2 15 76 9.8E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS01070 06796ae683ed72fe7f1386027f0e8f26 310 Gene3D G3DSA:1.10.1740.10 15 78 7.7E-10 T 06-07-2017 SMD11_RS01070 06796ae683ed72fe7f1386027f0e8f26 310 SUPERFAMILY SSF88946 15 94 1.49E-11 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS01070 06796ae683ed72fe7f1386027f0e8f26 310 SUPERFAMILY SSF54427 186 301 1.46E-14 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS03185 2fbc82c16d6bee33988a199e60b14a12 424 SUPERFAMILY SSF51905 38 206 3.0E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03185 2fbc82c16d6bee33988a199e60b14a12 424 SUPERFAMILY SSF51905 295 377 3.0E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03185 2fbc82c16d6bee33988a199e60b14a12 424 Pfam PF00890 FAD binding domain 39 84 7.0E-8 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS03185 2fbc82c16d6bee33988a199e60b14a12 424 Gene3D G3DSA:3.50.50.60 38 192 8.0E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03185 2fbc82c16d6bee33988a199e60b14a12 424 Gene3D G3DSA:3.30.9.10 202 341 7.2E-25 T 06-07-2017 SMD11_RS03185 2fbc82c16d6bee33988a199e60b14a12 424 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 38 333 4.0E-78 T 06-07-2017 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 SMD11_RS03185 2fbc82c16d6bee33988a199e60b14a12 424 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 313 2.3E-12 T 06-07-2017 SMD11_RS03185 2fbc82c16d6bee33988a199e60b14a12 424 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 39 61 2.3E-12 T 06-07-2017 SMD11_RS03185 2fbc82c16d6bee33988a199e60b14a12 424 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 179 194 2.3E-12 T 06-07-2017 SMD11_RS16880 3d0545302f2b432d5034fc8d0a8468c9 172 SUPERFAMILY SSF82708 126 171 1.24E-11 T 06-07-2017 IPR001374 R3H domain GO:0003676 SMD11_RS16880 3d0545302f2b432d5034fc8d0a8468c9 172 Gene3D G3DSA:3.30.300.120 22 104 8.7E-22 T 06-07-2017 SMD11_RS16880 3d0545302f2b432d5034fc8d0a8468c9 172 Pfam PF01424 R3H domain 113 169 3.5E-17 T 06-07-2017 IPR001374 R3H domain GO:0003676 SMD11_RS16880 3d0545302f2b432d5034fc8d0a8468c9 172 Pfam PF13083 KH domain 29 99 2.2E-7 T 06-07-2017 SMD11_RS16880 3d0545302f2b432d5034fc8d0a8468c9 172 Gene3D G3DSA:3.30.1370.50 105 171 2.4E-24 T 06-07-2017 IPR001374 R3H domain GO:0003676 SMD11_RS16880 3d0545302f2b432d5034fc8d0a8468c9 172 SMART SM00393 94 172 4.8E-27 T 06-07-2017 IPR001374 R3H domain GO:0003676 SMD11_RS24575 dda43f43dfa61612c6b90d338fd97595 187 ProSitePatterns PS00855 Signal peptidases II signature. 121 133 - T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMD11_RS24575 dda43f43dfa61612c6b90d338fd97595 187 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 29 181 14.114 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMD11_RS24575 dda43f43dfa61612c6b90d338fd97595 187 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 76 84 5.5E-15 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMD11_RS24575 dda43f43dfa61612c6b90d338fd97595 187 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 118 133 5.5E-15 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMD11_RS24575 dda43f43dfa61612c6b90d338fd97595 187 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 156 172 5.5E-15 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMD11_RS24575 dda43f43dfa61612c6b90d338fd97595 187 TIGRFAM TIGR00077 lspA: signal peptidase II 32 175 3.7E-23 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMD11_RS24575 dda43f43dfa61612c6b90d338fd97595 187 Pfam PF01252 Signal peptidase (SPase) II 38 175 1.1E-27 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SMD11_RS23405 a656bfc1c3de0f4719196707df61178c 121 Gene3D G3DSA:2.60.120.10 5 105 6.8E-8 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS23405 a656bfc1c3de0f4719196707df61178c 121 SUPERFAMILY SSF51182 53 111 2.93E-7 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS01420 ff8d029af9e5e5e15e61659bc0529942 350 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 40 339 7.6E-23 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS01420 ff8d029af9e5e5e15e61659bc0529942 350 SUPERFAMILY SSF56219 35 344 3.66E-41 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS01420 ff8d029af9e5e5e15e61659bc0529942 350 Gene3D G3DSA:3.60.10.10 31 344 2.6E-15 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS30970 40e39ed783a94712ba51939401a2453f 219 SUPERFAMILY SSF51735 1 194 1.64E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30970 40e39ed783a94712ba51939401a2453f 219 Gene3D G3DSA:3.40.50.720 1 203 8.6E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30970 40e39ed783a94712ba51939401a2453f 219 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 93 1.1E-22 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMD11_RS26785 65527accd5f56c75853e20c7abb7ad17 297 SUPERFAMILY SSF103481 169 273 2.09E-13 T 06-07-2017 SMD11_RS26785 65527accd5f56c75853e20c7abb7ad17 297 Pfam PF00892 EamA-like transporter family 135 268 8.9E-20 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS26785 65527accd5f56c75853e20c7abb7ad17 297 Pfam PF00892 EamA-like transporter family 3 125 3.5E-13 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS26785 65527accd5f56c75853e20c7abb7ad17 297 SUPERFAMILY SSF103481 38 127 1.1E-14 T 06-07-2017 SMD11_RS12100 4e4e7fd7146ddf7dd3869047cb07d244 313 Pfam PF00561 alpha/beta hydrolase fold 58 161 6.1E-20 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS12100 4e4e7fd7146ddf7dd3869047cb07d244 313 Gene3D G3DSA:3.40.50.1820 35 312 4.7E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12100 4e4e7fd7146ddf7dd3869047cb07d244 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 82 97 1.5E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS12100 4e4e7fd7146ddf7dd3869047cb07d244 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 140 153 1.5E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS12100 4e4e7fd7146ddf7dd3869047cb07d244 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 126 139 1.5E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS12100 4e4e7fd7146ddf7dd3869047cb07d244 313 SUPERFAMILY SSF53474 24 312 3.13E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS17250 8359c8c9012f85c44d550c1148fc2071 490 SUPERFAMILY SSF52777 251 487 1.02E-76 T 06-07-2017 SMD11_RS17250 8359c8c9012f85c44d550c1148fc2071 490 Pfam PF00364 Biotin-requiring enzyme 13 83 5.0E-22 T 06-07-2017 IPR000089 Biotin/lipoyl attachment SMD11_RS17250 8359c8c9012f85c44d550c1148fc2071 490 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 259 487 1.3E-78 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD11_RS17250 8359c8c9012f85c44d550c1148fc2071 490 Gene3D G3DSA:3.30.559.10 254 487 1.4E-83 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 SMD11_RS17250 8359c8c9012f85c44d550c1148fc2071 490 Pfam PF02817 e3 binding domain 186 220 2.4E-12 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD11_RS17250 8359c8c9012f85c44d550c1148fc2071 490 Gene3D G3DSA:2.40.50.100 12 105 1.1E-26 T 06-07-2017 SMD11_RS17250 8359c8c9012f85c44d550c1148fc2071 490 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 36 65 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SMD11_RS17250 8359c8c9012f85c44d550c1148fc2071 490 SUPERFAMILY SSF47005 184 224 6.67E-10 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD11_RS17250 8359c8c9012f85c44d550c1148fc2071 490 SUPERFAMILY SSF51230 11 104 3.8E-26 T 06-07-2017 IPR011053 Single hybrid motif SMD11_RS17250 8359c8c9012f85c44d550c1148fc2071 490 Gene3D G3DSA:4.10.320.10 184 230 1.2E-15 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SMD11_RS04050 db74c15d6a9e868011e4dabeb3def62e 382 Gene3D G3DSA:3.40.50.1100 174 340 1.7E-37 T 06-07-2017 SMD11_RS04050 db74c15d6a9e868011e4dabeb3def62e 382 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 45 326 3.6E-49 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS04050 db74c15d6a9e868011e4dabeb3def62e 382 Gene3D G3DSA:3.40.50.1100 75 173 2.2E-20 T 06-07-2017 SMD11_RS04050 db74c15d6a9e868011e4dabeb3def62e 382 SUPERFAMILY SSF53686 38 347 4.19E-63 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS06640 25a7421685c0f0191e12fb2454a20114 153 SUPERFAMILY SSF46785 16 151 6.12E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06640 25a7421685c0f0191e12fb2454a20114 153 Pfam PF12802 MarR family 43 100 1.8E-7 T 06-07-2017 SMD11_RS06640 25a7421685c0f0191e12fb2454a20114 153 Gene3D G3DSA:1.10.10.10 5 149 2.4E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06640 25a7421685c0f0191e12fb2454a20114 153 SMART SM00347 35 137 8.0E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS06890 9b16fd65aafe5ef4eba929ad9e4f0ab8 217 Pfam PF03070 TENA/THI-4/PQQC family 24 185 1.8E-5 T 06-07-2017 IPR004305 Thiaminase-2/PQQC SMD11_RS06890 9b16fd65aafe5ef4eba929ad9e4f0ab8 217 Gene3D G3DSA:1.20.910.10 23 214 2.1E-11 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS06890 9b16fd65aafe5ef4eba929ad9e4f0ab8 217 SUPERFAMILY SSF48613 25 215 1.58E-26 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS14085 a405f38f4bbe779f7e036b721c1f0ed6 381 Gene3D G3DSA:3.40.350.10 16 122 9.3E-14 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SMD11_RS14085 a405f38f4bbe779f7e036b721c1f0ed6 381 Gene3D G3DSA:3.90.230.10 155 379 4.9E-69 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS14085 a405f38f4bbe779f7e036b721c1f0ed6 381 SUPERFAMILY SSF53092 15 152 4.01E-15 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal SMD11_RS14085 a405f38f4bbe779f7e036b721c1f0ed6 381 SUPERFAMILY SSF55920 154 380 3.66E-72 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS14085 a405f38f4bbe779f7e036b721c1f0ed6 381 Pfam PF01321 Creatinase/Prolidase N-terminal domain 24 155 8.0E-15 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 SMD11_RS14085 a405f38f4bbe779f7e036b721c1f0ed6 381 Pfam PF00557 Metallopeptidase family M24 164 364 9.5E-58 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS24515 2730d5fef5fe8406fd90cd215e0d22fe 364 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 351 1.1E-87 T 06-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD11_RS24515 2730d5fef5fe8406fd90cd215e0d22fe 364 Gene3D G3DSA:3.40.50.2000 2 185 3.3E-61 T 06-07-2017 SMD11_RS24515 2730d5fef5fe8406fd90cd215e0d22fe 364 SUPERFAMILY SSF53756 2 357 5.07E-100 T 06-07-2017 SMD11_RS24515 2730d5fef5fe8406fd90cd215e0d22fe 364 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 358 31.798 T 06-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD11_RS24515 2730d5fef5fe8406fd90cd215e0d22fe 364 Gene3D G3DSA:3.40.50.2000 186 343 1.9E-18 T 06-07-2017 SMD11_RS24515 2730d5fef5fe8406fd90cd215e0d22fe 364 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 348 2.6E-40 T 06-07-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 SMD11_RS24515 2730d5fef5fe8406fd90cd215e0d22fe 364 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 142 2.7E-43 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD11_RS16155 4c73e88fe0c13fa243dec9fca152cf7d 421 Pfam PF07690 Major Facilitator Superfamily 45 265 3.9E-24 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS16155 4c73e88fe0c13fa243dec9fca152cf7d 421 Gene3D G3DSA:1.20.1250.20 245 411 8.8E-13 T 06-07-2017 SMD11_RS16155 4c73e88fe0c13fa243dec9fca152cf7d 421 SUPERFAMILY SSF103473 34 411 1.44E-47 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS16155 4c73e88fe0c13fa243dec9fca152cf7d 421 Gene3D G3DSA:1.20.1250.20 41 223 5.7E-20 T 06-07-2017 SMD11_RS26725 2e6447b582af86516f5c271e30eb699e 387 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 338 1.1E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS26725 2e6447b582af86516f5c271e30eb699e 387 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 358 1.1E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS26725 2e6447b582af86516f5c271e30eb699e 387 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 324 1.1E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS26725 2e6447b582af86516f5c271e30eb699e 387 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 377 1.1E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS26725 2e6447b582af86516f5c271e30eb699e 387 SMART SM00387 270 380 8.6E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS26725 2e6447b582af86516f5c271e30eb699e 387 SUPERFAMILY SSF55785 42 138 9.25E-11 T 06-07-2017 IPR000014 PAS domain SMD11_RS26725 2e6447b582af86516f5c271e30eb699e 387 Gene3D G3DSA:1.10.287.130 150 210 1.8E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS26725 2e6447b582af86516f5c271e30eb699e 387 Gene3D G3DSA:3.30.450.20 42 95 1.8E-11 T 06-07-2017 SMD11_RS26725 2e6447b582af86516f5c271e30eb699e 387 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 271 378 9.8E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS26725 2e6447b582af86516f5c271e30eb699e 387 SMART SM00388 157 225 4.1E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS26725 2e6447b582af86516f5c271e30eb699e 387 Pfam PF00512 His Kinase A (phospho-acceptor) domain 159 225 2.1E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS26725 2e6447b582af86516f5c271e30eb699e 387 SUPERFAMILY SSF55874 215 378 1.11E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS26725 2e6447b582af86516f5c271e30eb699e 387 Gene3D G3DSA:3.30.565.10 211 378 4.0E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS26725 2e6447b582af86516f5c271e30eb699e 387 SUPERFAMILY SSF47384 148 226 8.83E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS26725 2e6447b582af86516f5c271e30eb699e 387 Pfam PF00989 PAS fold 43 88 1.6E-6 T 06-07-2017 IPR013767 PAS fold GO:0006355 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 Pfam PF00425 chorismate binding enzyme 424 678 9.9E-89 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 77 93 1.9E-6 T 06-07-2017 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 1.9E-6 T 06-07-2017 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 Gene3D G3DSA:3.60.120.10 224 686 4.3E-146 T 06-07-2017 IPR005801 ADC synthase GO:0009058 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 Gene3D G3DSA:3.40.50.880 2 190 8.5E-66 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 SUPERFAMILY SSF52317 2 190 5.73E-54 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 SUPERFAMILY SSF56322 225 686 1.44E-129 T 06-07-2017 IPR005801 ADC synthase GO:0009058 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 Pfam PF04715 Anthranilate synthase component I, N terminal region 240 375 2.3E-16 T 06-07-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 PRINTS PR00097 Anthranilate synthase component II signature 122 134 1.4E-29 T 06-07-2017 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 PRINTS PR00097 Anthranilate synthase component II signature 77 88 1.4E-29 T 06-07-2017 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 PRINTS PR00097 Anthranilate synthase component II signature 165 178 1.4E-29 T 06-07-2017 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 PRINTS PR00097 Anthranilate synthase component II signature 49 58 1.4E-29 T 06-07-2017 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 PRINTS PR00097 Anthranilate synthase component II signature 3 17 1.4E-29 T 06-07-2017 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 PRINTS PR00097 Anthranilate synthase component II signature 102 110 1.4E-29 T 06-07-2017 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 330 681 1.1E-115 T 06-07-2017 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 Pfam PF00117 Glutamine amidotransferase class-I 5 185 3.3E-46 T 06-07-2017 IPR017926 Glutamine amidotransferase SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 185 1.3E-49 T 06-07-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 7.4E-12 T 06-07-2017 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 7.4E-12 T 06-07-2017 SMD11_RS08440 546a99fc1f601531f0048dd84cd3d9a5 700 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 7.4E-12 T 06-07-2017 SMD11_RS11345 947eb9ad2f994f61cb698e839238fe76 541 Pfam PF00474 Sodium:solute symporter family 44 415 1.0E-20 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD11_RS11960 902a6fa733b001093bc68dc9878920d9 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 324 9.8E-32 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11960 902a6fa733b001093bc68dc9878920d9 325 Gene3D G3DSA:1.10.3720.10 101 321 2.8E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11960 902a6fa733b001093bc68dc9878920d9 325 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 18 54 6.7E-10 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD11_RS11960 902a6fa733b001093bc68dc9878920d9 325 SUPERFAMILY SSF161098 105 309 3.01E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS01085 822f068281c6a8c10d58abdce5c46333 309 Pfam PF13560 Helix-turn-helix domain 6 85 8.4E-18 T 06-07-2017 SMD11_RS01085 822f068281c6a8c10d58abdce5c46333 309 Gene3D G3DSA:1.10.260.40 4 81 1.7E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS01085 822f068281c6a8c10d58abdce5c46333 309 SUPERFAMILY SSF47413 29 81 3.26E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS01085 822f068281c6a8c10d58abdce5c46333 309 SMART SM00530 9 82 5.4E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS12200 efc638d54be79888eb5fe43f08509e4b 487 SUPERFAMILY SSF56634 6 485 3.14E-202 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS12200 efc638d54be79888eb5fe43f08509e4b 487 Pfam PF00199 Catalase 12 390 4.7E-186 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS12200 efc638d54be79888eb5fe43f08509e4b 487 PRINTS PR00067 Catalase signature 324 350 4.1E-66 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS12200 efc638d54be79888eb5fe43f08509e4b 487 PRINTS PR00067 Catalase signature 87 105 4.1E-66 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS12200 efc638d54be79888eb5fe43f08509e4b 487 PRINTS PR00067 Catalase signature 108 125 4.1E-66 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS12200 efc638d54be79888eb5fe43f08509e4b 487 PRINTS PR00067 Catalase signature 25 48 4.1E-66 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS12200 efc638d54be79888eb5fe43f08509e4b 487 PRINTS PR00067 Catalase signature 127 145 4.1E-66 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS12200 efc638d54be79888eb5fe43f08509e4b 487 PRINTS PR00067 Catalase signature 292 319 4.1E-66 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS12200 efc638d54be79888eb5fe43f08509e4b 487 Gene3D G3DSA:2.40.180.10 4 361 3.9E-176 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS12200 efc638d54be79888eb5fe43f08509e4b 487 PIRSF PIRSF038928 2 487 1.3E-230 T 06-07-2017 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS12200 efc638d54be79888eb5fe43f08509e4b 487 Pfam PF06628 Catalase-related immune-responsive 422 483 1.8E-16 T 06-07-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS12200 efc638d54be79888eb5fe43f08509e4b 487 ProSitePatterns PS00438 Catalase proximal active site signature. 48 64 - T 06-07-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS12200 efc638d54be79888eb5fe43f08509e4b 487 SMART SM01060 12 394 9.4E-277 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS12200 efc638d54be79888eb5fe43f08509e4b 487 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 337 345 - T 06-07-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS14505 0aa5335f97c31d31a7420d783c7e114e 254 SUPERFAMILY SSF46955 3 109 3.0E-27 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS14505 0aa5335f97c31d31a7420d783c7e114e 254 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS14505 0aa5335f97c31d31a7420d783c7e114e 254 SUPERFAMILY SSF89082 162 250 1.96E-22 T 06-07-2017 IPR012925 TipAS antibiotic-recognition domain SMD11_RS14505 0aa5335f97c31d31a7420d783c7e114e 254 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 2.9E-5 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS14505 0aa5335f97c31d31a7420d783c7e114e 254 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 2.9E-5 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS14505 0aa5335f97c31d31a7420d783c7e114e 254 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 2.9E-5 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS14505 0aa5335f97c31d31a7420d783c7e114e 254 SMART SM00422 3 72 9.7E-22 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS14505 0aa5335f97c31d31a7420d783c7e114e 254 Gene3D G3DSA:1.10.490.50 163 250 3.3E-25 T 06-07-2017 IPR012925 TipAS antibiotic-recognition domain SMD11_RS14505 0aa5335f97c31d31a7420d783c7e114e 254 Gene3D G3DSA:1.10.1660.10 4 114 3.4E-29 T 06-07-2017 SMD11_RS14505 0aa5335f97c31d31a7420d783c7e114e 254 Pfam PF13411 MerR HTH family regulatory protein 4 71 2.0E-17 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS14505 0aa5335f97c31d31a7420d783c7e114e 254 Pfam PF07739 TipAS antibiotic-recognition domain 137 248 9.6E-28 T 06-07-2017 IPR012925 TipAS antibiotic-recognition domain SMD11_RS14515 8567c5cea71300da7f2d61d4bd165fdb 298 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 154 4.0E-20 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS14515 8567c5cea71300da7f2d61d4bd165fdb 298 Gene3D G3DSA:3.10.450.50 163 281 1.2E-14 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS14515 8567c5cea71300da7f2d61d4bd165fdb 298 SUPERFAMILY SSF88946 5 83 1.26E-12 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS14515 8567c5cea71300da7f2d61d4bd165fdb 298 Pfam PF08281 Sigma-70, region 4 102 153 1.8E-12 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS14515 8567c5cea71300da7f2d61d4bd165fdb 298 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 5 281 6.1E-102 T 06-07-2017 IPR014303 RNA polymerase sigma-70, ECF type SMD11_RS14515 8567c5cea71300da7f2d61d4bd165fdb 298 SUPERFAMILY SSF54427 167 284 2.45E-16 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS14515 8567c5cea71300da7f2d61d4bd165fdb 298 Gene3D G3DSA:1.10.10.10 98 156 7.3E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14515 8567c5cea71300da7f2d61d4bd165fdb 298 Gene3D G3DSA:1.10.1740.10 4 71 4.7E-12 T 06-07-2017 SMD11_RS14515 8567c5cea71300da7f2d61d4bd165fdb 298 SUPERFAMILY SSF88659 94 155 1.85E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS14515 8567c5cea71300da7f2d61d4bd165fdb 298 Pfam PF04542 Sigma-70 region 2 6 67 1.2E-14 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19005 d9f5061010a88e214ddc08cdadbc6246 73 SMART SM00316 5 73 6.0E-5 T 06-07-2017 IPR022967 RNA-binding domain, S1 SMD11_RS19005 d9f5061010a88e214ddc08cdadbc6246 73 SUPERFAMILY SSF50249 4 72 9.06E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS19005 d9f5061010a88e214ddc08cdadbc6246 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 3.4E-29 T 06-07-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 SMD11_RS19005 d9f5061010a88e214ddc08cdadbc6246 73 Gene3D G3DSA:2.40.50.140 2 73 1.5E-39 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS19005 d9f5061010a88e214ddc08cdadbc6246 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 6.4E-38 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 SMD11_RS19005 d9f5061010a88e214ddc08cdadbc6246 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.761 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 SMD11_RS29215 bab66fd9422dc9730405829d7a13bfd1 237 Gene3D G3DSA:3.90.550.10 1 229 6.6E-55 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS29215 bab66fd9422dc9730405829d7a13bfd1 237 SUPERFAMILY SSF53448 1 226 9.53E-58 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS29215 bab66fd9422dc9730405829d7a13bfd1 237 Pfam PF00483 Nucleotidyl transferase 4 225 1.8E-32 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMD11_RS29400 c96c7b32dbfb97b9744ad3edbb7287ca 617 Gene3D G3DSA:3.40.50.620 470 567 1.9E-74 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS29400 c96c7b32dbfb97b9744ad3edbb7287ca 617 Gene3D G3DSA:3.40.50.620 225 402 1.9E-74 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS29400 c96c7b32dbfb97b9744ad3edbb7287ca 617 Pfam PF00733 Asparagine synthase 241 590 6.6E-84 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMD11_RS29400 c96c7b32dbfb97b9744ad3edbb7287ca 617 Pfam PF13537 Glutamine amidotransferase domain 48 170 2.5E-44 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain SMD11_RS29400 c96c7b32dbfb97b9744ad3edbb7287ca 617 Gene3D G3DSA:3.60.20.10 1 224 3.7E-73 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS29400 c96c7b32dbfb97b9744ad3edbb7287ca 617 PIRSF PIRSF001589 1 616 7.3E-139 T 06-07-2017 SMD11_RS29400 c96c7b32dbfb97b9744ad3edbb7287ca 617 SUPERFAMILY SSF52402 466 600 1.05E-66 T 06-07-2017 SMD11_RS29400 c96c7b32dbfb97b9744ad3edbb7287ca 617 SUPERFAMILY SSF52402 230 398 1.05E-66 T 06-07-2017 SMD11_RS29400 c96c7b32dbfb97b9744ad3edbb7287ca 617 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 546 3.1E-148 T 06-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SMD11_RS29400 c96c7b32dbfb97b9744ad3edbb7287ca 617 SUPERFAMILY SSF56235 1 225 2.57E-63 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS11395 1190b17194fc24d038d636aeaf5a8e42 281 SUPERFAMILY SSF88659 188 250 5.61E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11395 1190b17194fc24d038d636aeaf5a8e42 281 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 108 139 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11395 1190b17194fc24d038d636aeaf5a8e42 281 Gene3D G3DSA:1.10.1740.10 76 155 1.9E-28 T 06-07-2017 SMD11_RS11395 1190b17194fc24d038d636aeaf5a8e42 281 Pfam PF08281 Sigma-70, region 4 195 245 8.8E-14 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11395 1190b17194fc24d038d636aeaf5a8e42 281 SUPERFAMILY SSF88946 80 168 4.45E-24 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11395 1190b17194fc24d038d636aeaf5a8e42 281 Gene3D G3DSA:1.10.10.10 188 252 5.0E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11395 1190b17194fc24d038d636aeaf5a8e42 281 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 74 260 4.2E-108 T 06-07-2017 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11395 1190b17194fc24d038d636aeaf5a8e42 281 Pfam PF04542 Sigma-70 region 2 90 153 5.4E-18 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11395 1190b17194fc24d038d636aeaf5a8e42 281 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 89 248 6.0E-26 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS32605 757f83bea2720d1a639ed8397908d7f6 225 Gene3D G3DSA:3.40.50.300 2 215 7.1E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS32605 757f83bea2720d1a639ed8397908d7f6 225 Pfam PF00005 ABC transporter 18 161 1.1E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS32605 757f83bea2720d1a639ed8397908d7f6 225 SMART SM00382 26 206 1.5E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS32605 757f83bea2720d1a639ed8397908d7f6 225 SUPERFAMILY SSF52540 3 213 2.66E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS32605 757f83bea2720d1a639ed8397908d7f6 225 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS15175 2bdfc7d73a626ef526c67e27575f1375 215 Pfam PF00990 Diguanylate cyclase, GGDEF domain 32 181 6.5E-28 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS15175 2bdfc7d73a626ef526c67e27575f1375 215 SMART SM00267 21 188 4.7E-36 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS15175 2bdfc7d73a626ef526c67e27575f1375 215 SUPERFAMILY SSF55073 37 188 5.89E-32 T 06-07-2017 IPR029787 Nucleotide cyclase SMD11_RS15175 2bdfc7d73a626ef526c67e27575f1375 215 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 30 181 1.7E-22 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS15175 2bdfc7d73a626ef526c67e27575f1375 215 Gene3D G3DSA:3.30.70.270 34 183 2.6E-35 T 06-07-2017 SMD11_RS30430 be58d94cf7288730fafbff0f870d96c7 392 SUPERFAMILY SSF56059 93 301 1.85E-29 T 06-07-2017 SMD11_RS30430 be58d94cf7288730fafbff0f870d96c7 392 Pfam PF02655 ATP-grasp domain 95 266 8.5E-6 T 06-07-2017 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 SMD11_RS30430 be58d94cf7288730fafbff0f870d96c7 392 Gene3D G3DSA:3.30.470.20 93 298 6.7E-24 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS01460 21ab40963945ed742afb5ad54b236465 162 SUPERFAMILY SSF50475 4 144 1.16E-21 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS01460 21ab40963945ed742afb5ad54b236465 162 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 11 136 1.4E-7 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related SMD11_RS01460 21ab40963945ed742afb5ad54b236465 162 Gene3D G3DSA:2.30.110.10 6 143 9.7E-21 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS32585 57ac4fe268190e72601710795f2beddf 407 Pfam PF02803 Thiolase, C-terminal domain 281 403 1.3E-25 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD11_RS32585 57ac4fe268190e72601710795f2beddf 407 SUPERFAMILY SSF53901 17 272 4.21E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32585 57ac4fe268190e72601710795f2beddf 407 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMD11_RS32585 57ac4fe268190e72601710795f2beddf 407 PIRSF PIRSF000429 14 405 5.5E-115 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS32585 57ac4fe268190e72601710795f2beddf 407 Pfam PF00108 Thiolase, N-terminal domain 20 265 4.4E-67 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD11_RS32585 57ac4fe268190e72601710795f2beddf 407 Gene3D G3DSA:3.40.47.10 158 202 1.2E-45 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32585 57ac4fe268190e72601710795f2beddf 407 Gene3D G3DSA:3.40.47.10 281 403 1.2E-45 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32585 57ac4fe268190e72601710795f2beddf 407 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 21 403 1.2E-108 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS32585 57ac4fe268190e72601710795f2beddf 407 Gene3D G3DSA:3.40.47.10 20 136 5.6E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32585 57ac4fe268190e72601710795f2beddf 407 Gene3D G3DSA:3.40.47.10 203 274 5.6E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32585 57ac4fe268190e72601710795f2beddf 407 SUPERFAMILY SSF53901 280 403 1.77E-26 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS23250 1f61b81e8c9fc7c76017489f2e6acd3f 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 1.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS23250 1f61b81e8c9fc7c76017489f2e6acd3f 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 1.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS23250 1f61b81e8c9fc7c76017489f2e6acd3f 219 Gene3D G3DSA:1.10.10.60 16 71 9.6E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS23250 1f61b81e8c9fc7c76017489f2e6acd3f 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 73 6.2E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS23250 1f61b81e8c9fc7c76017489f2e6acd3f 219 SUPERFAMILY SSF46689 16 95 7.18E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS23250 1f61b81e8c9fc7c76017489f2e6acd3f 219 ProSitePatterns PS01081 TetR-type HTH domain signature. 40 70 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD11_RS23250 1f61b81e8c9fc7c76017489f2e6acd3f 219 Gene3D G3DSA:1.10.357.10 72 213 3.3E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS07375 8c5886770e71a7b907f93cc7afe6a3d8 217 SUPERFAMILY SSF102462 122 209 3.31E-20 T 06-07-2017 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 SMD11_RS07375 8c5886770e71a7b907f93cc7afe6a3d8 217 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 123 209 2.4E-8 T 06-07-2017 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 SMD11_RS07375 8c5886770e71a7b907f93cc7afe6a3d8 217 Gene3D G3DSA:3.40.1490.10 122 209 5.8E-17 T 06-07-2017 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 SMD11_RS07215 df8370afe5684198c708e52f8f8caa59 436 Gene3D G3DSA:2.40.30.10 220 346 7.0E-19 T 06-07-2017 SMD11_RS07215 df8370afe5684198c708e52f8f8caa59 436 Pfam PF00009 Elongation factor Tu GTP binding domain 7 190 6.1E-39 T 06-07-2017 SMD11_RS07215 df8370afe5684198c708e52f8f8caa59 436 SUPERFAMILY SSF50447 220 307 1.51E-17 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS07215 df8370afe5684198c708e52f8f8caa59 436 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site SMD11_RS07215 df8370afe5684198c708e52f8f8caa59 436 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 7 414 1.2E-162 T 06-07-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMD11_RS07215 df8370afe5684198c708e52f8f8caa59 436 SUPERFAMILY SSF50465 314 414 3.93E-24 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SMD11_RS07215 df8370afe5684198c708e52f8f8caa59 436 Gene3D G3DSA:3.40.50.300 5 211 2.8E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07215 df8370afe5684198c708e52f8f8caa59 436 PRINTS PR00315 GTP-binding elongation factor signature 103 114 4.3E-12 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS07215 df8370afe5684198c708e52f8f8caa59 436 PRINTS PR00315 GTP-binding elongation factor signature 8 21 4.3E-12 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS07215 df8370afe5684198c708e52f8f8caa59 436 PRINTS PR00315 GTP-binding elongation factor signature 140 149 4.3E-12 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS07215 df8370afe5684198c708e52f8f8caa59 436 PRINTS PR00315 GTP-binding elongation factor signature 67 75 4.3E-12 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS07215 df8370afe5684198c708e52f8f8caa59 436 PRINTS PR00315 GTP-binding elongation factor signature 87 97 4.3E-12 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS07215 df8370afe5684198c708e52f8f8caa59 436 SUPERFAMILY SSF52540 5 226 1.18E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 Pfam PF02540 NAD synthase 222 296 1.6E-7 T 06-07-2017 IPR022310 NAD/GMP synthase SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 Gene3D G3DSA:3.40.50.620 207 405 6.9E-57 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 16 198 7.9E-72 T 06-07-2017 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 SUPERFAMILY SSF52317 16 207 4.9E-52 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 Pfam PF00117 Glutamine amidotransferase class-I 18 198 6.2E-40 T 06-07-2017 IPR017926 Glutamine amidotransferase SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 Pfam PF00958 GMP synthase C terminal domain 438 530 9.0E-39 T 06-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 211 531 1.1E-146 T 06-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 16 30 4.0E-6 T 06-07-2017 SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 57 71 4.0E-6 T 06-07-2017 SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 87 103 4.0E-6 T 06-07-2017 SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 13 531 53.756 T 06-07-2017 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 Gene3D G3DSA:3.40.50.880 8 198 5.2E-57 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 SUPERFAMILY SSF54810 410 531 1.83E-47 T 06-07-2017 SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 PRINTS PR00096 Glutamine amidotransferase superfamily signature 87 98 9.5E-8 T 06-07-2017 SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 PRINTS PR00096 Glutamine amidotransferase superfamily signature 176 189 9.5E-8 T 06-07-2017 SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 PRINTS PR00096 Glutamine amidotransferase superfamily signature 60 69 9.5E-8 T 06-07-2017 SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 PRINTS PR00097 Anthranilate synthase component II signature 176 189 1.1E-5 T 06-07-2017 SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 PRINTS PR00097 Anthranilate synthase component II signature 87 98 1.1E-5 T 06-07-2017 SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 PRINTS PR00097 Anthranilate synthase component II signature 60 69 1.1E-5 T 06-07-2017 SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 SUPERFAMILY SSF52402 192 451 2.21E-57 T 06-07-2017 SMD11_RS13350 d9fa51526c18c754c9adc3b901e51c0a 531 Gene3D G3DSA:3.30.300.10 406 531 5.4E-49 T 06-07-2017 SMD11_RS05840 23634df68535dc0a1752f75c4c0cc7d2 192 SUPERFAMILY SSF48498 76 191 8.35E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS05840 23634df68535dc0a1752f75c4c0cc7d2 192 SUPERFAMILY SSF46689 3 65 3.44E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS05840 23634df68535dc0a1752f75c4c0cc7d2 192 Gene3D G3DSA:1.10.357.10 66 192 6.5E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS05840 23634df68535dc0a1752f75c4c0cc7d2 192 Gene3D G3DSA:1.10.10.60 3 65 5.6E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS05840 23634df68535dc0a1752f75c4c0cc7d2 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 4.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS05840 23634df68535dc0a1752f75c4c0cc7d2 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 4.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS05840 23634df68535dc0a1752f75c4c0cc7d2 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 3.0E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS21955 e37a08f0e18ce54ae706bedee170f338 368 SUPERFAMILY SSF51905 6 109 3.89E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS21955 e37a08f0e18ce54ae706bedee170f338 368 SUPERFAMILY SSF51905 234 309 3.89E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS21955 e37a08f0e18ce54ae706bedee170f338 368 Gene3D G3DSA:3.50.50.60 60 140 3.0E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS21955 e37a08f0e18ce54ae706bedee170f338 368 Gene3D G3DSA:3.50.50.60 228 290 3.0E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS16280 3241aa61dc37b59af4d0affb2d0b7c1d 171 SUPERFAMILY SSF55874 44 141 2.26E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16280 3241aa61dc37b59af4d0affb2d0b7c1d 171 Gene3D G3DSA:3.30.565.10 24 142 2.8E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16280 3241aa61dc37b59af4d0affb2d0b7c1d 171 Pfam PF13581 Histidine kinase-like ATPase domain 20 140 1.0E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS18125 549bd407b02a267cfcb9848ebe0ba7fc 714 Pfam PF04542 Sigma-70 region 2 138 197 5.0E-11 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS18125 549bd407b02a267cfcb9848ebe0ba7fc 714 SUPERFAMILY SSF88946 118 215 3.69E-18 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS18125 549bd407b02a267cfcb9848ebe0ba7fc 714 PRINTS PR01217 Proline rich extensin signature 470 486 3.0E-10 T 06-07-2017 SMD11_RS18125 549bd407b02a267cfcb9848ebe0ba7fc 714 PRINTS PR01217 Proline rich extensin signature 532 548 3.0E-10 T 06-07-2017 SMD11_RS18125 549bd407b02a267cfcb9848ebe0ba7fc 714 PRINTS PR01217 Proline rich extensin signature 506 527 3.0E-10 T 06-07-2017 SMD11_RS18125 549bd407b02a267cfcb9848ebe0ba7fc 714 PRINTS PR01217 Proline rich extensin signature 490 502 3.0E-10 T 06-07-2017 SMD11_RS18125 549bd407b02a267cfcb9848ebe0ba7fc 714 SUPERFAMILY SSF88659 242 301 4.49E-7 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS18125 549bd407b02a267cfcb9848ebe0ba7fc 714 SMART SM00776 569 713 3.8E-31 T 06-07-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module SMD11_RS18125 549bd407b02a267cfcb9848ebe0ba7fc 714 Gene3D G3DSA:1.10.1740.10 119 229 1.5E-19 T 06-07-2017 SMD11_RS18125 549bd407b02a267cfcb9848ebe0ba7fc 714 Pfam PF08305 NPCBM/NEW2 domain 603 711 3.6E-28 T 06-07-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module SMD11_RS18125 549bd407b02a267cfcb9848ebe0ba7fc 714 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 134 302 1.1E-16 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS18125 549bd407b02a267cfcb9848ebe0ba7fc 714 SUPERFAMILY SSF49785 575 711 1.91E-28 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS18125 549bd407b02a267cfcb9848ebe0ba7fc 714 Gene3D G3DSA:1.10.10.10 244 302 9.0E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00720 78bd8edea0efcbb34ffcf10e32892994 143 SUPERFAMILY SSF49764 18 134 1.43E-30 T 06-07-2017 IPR008978 HSP20-like chaperone SMD11_RS00720 78bd8edea0efcbb34ffcf10e32892994 143 Gene3D G3DSA:2.60.40.790 6 134 4.8E-31 T 06-07-2017 IPR008978 HSP20-like chaperone SMD11_RS00720 78bd8edea0efcbb34ffcf10e32892994 143 Pfam PF00011 Hsp20/alpha crystallin family 35 132 2.3E-20 T 06-07-2017 IPR002068 Alpha crystallin/Hsp20 domain SMD11_RS16355 746aa864d03d4befa5502d92d724dd7d 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 305 404 3.0E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16355 746aa864d03d4befa5502d92d724dd7d 427 Pfam PF07730 Histidine kinase 198 263 1.2E-10 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS16355 746aa864d03d4befa5502d92d724dd7d 427 SUPERFAMILY SSF55874 276 403 1.19E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16355 746aa864d03d4befa5502d92d724dd7d 427 Gene3D G3DSA:3.30.565.10 300 405 5.2E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS07410 2391d2c419f31cc58a5b84ea7620f047 193 Gene3D G3DSA:2.60.130.10 5 175 3.1E-44 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMD11_RS07410 2391d2c419f31cc58a5b84ea7620f047 193 Pfam PF00775 Dioxygenase 34 105 5.2E-8 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 SMD11_RS07410 2391d2c419f31cc58a5b84ea7620f047 193 SUPERFAMILY SSF49482 4 175 1.83E-35 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 SMD11_RS07410 2391d2c419f31cc58a5b84ea7620f047 193 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 6 174 1.4E-40 T 06-07-2017 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 SMD11_RS04780 348cb59c669b2d31ad37cfffef9a4672 465 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 89 101 2.2E-8 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS04780 348cb59c669b2d31ad37cfffef9a4672 465 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 314 333 2.2E-8 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS04780 348cb59c669b2d31ad37cfffef9a4672 465 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 69 87 2.2E-8 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS04780 348cb59c669b2d31ad37cfffef9a4672 465 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 194 207 2.2E-8 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS04780 348cb59c669b2d31ad37cfffef9a4672 465 Gene3D G3DSA:3.20.20.10 46 267 4.9E-39 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS04780 348cb59c669b2d31ad37cfffef9a4672 465 SUPERFAMILY SSF50621 307 442 3.92E-17 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS04780 348cb59c669b2d31ad37cfffef9a4672 465 Gene3D G3DSA:2.40.37.10 292 444 7.9E-26 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS04780 348cb59c669b2d31ad37cfffef9a4672 465 SUPERFAMILY SSF51419 276 327 1.96E-39 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS04780 348cb59c669b2d31ad37cfffef9a4672 465 SUPERFAMILY SSF51419 45 249 1.96E-39 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS04780 348cb59c669b2d31ad37cfffef9a4672 465 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 60 278 1.3E-20 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMD11_RS27170 185700824322ecfe3f9640c4dc215d3b 199 ProSitePatterns PS01236 PdxT/SNO family family signature. 47 57 - T 06-07-2017 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD11_RS27170 185700824322ecfe3f9640c4dc215d3b 199 Pfam PF01174 SNO glutamine amidotransferase family 12 196 9.6E-58 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD11_RS27170 185700824322ecfe3f9640c4dc215d3b 199 PIRSF PIRSF005639 5 199 5.1E-73 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD11_RS27170 185700824322ecfe3f9640c4dc215d3b 199 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 10 194 2.4E-79 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD11_RS27170 185700824322ecfe3f9640c4dc215d3b 199 Gene3D G3DSA:3.40.50.880 7 198 3.8E-78 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS27170 185700824322ecfe3f9640c4dc215d3b 199 SUPERFAMILY SSF52317 9 196 3.84E-52 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS27170 185700824322ecfe3f9640c4dc215d3b 199 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 10 195 37.25 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD11_RS31400 a34422417a8b38ee8081db5495f16556 378 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 10 373 2.9E-137 T 06-07-2017 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 SMD11_RS31400 a34422417a8b38ee8081db5495f16556 378 PRINTS PR00143 Citrate synthase signature 178 193 5.3E-40 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS31400 a34422417a8b38ee8081db5495f16556 378 PRINTS PR00143 Citrate synthase signature 200 228 5.3E-40 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS31400 a34422417a8b38ee8081db5495f16556 378 PRINTS PR00143 Citrate synthase signature 253 273 5.3E-40 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS31400 a34422417a8b38ee8081db5495f16556 378 PRINTS PR00143 Citrate synthase signature 333 347 5.3E-40 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS31400 a34422417a8b38ee8081db5495f16556 378 PRINTS PR00143 Citrate synthase signature 313 329 5.3E-40 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS31400 a34422417a8b38ee8081db5495f16556 378 PRINTS PR00143 Citrate synthase signature 129 142 5.3E-40 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS31400 a34422417a8b38ee8081db5495f16556 378 Gene3D G3DSA:1.10.580.10 19 239 2.5E-83 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SMD11_RS31400 a34422417a8b38ee8081db5495f16556 378 SUPERFAMILY SSF48256 9 373 7.07E-122 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS31400 a34422417a8b38ee8081db5495f16556 378 PIRSF PIRSF001369 4 377 2.2E-118 T 06-07-2017 IPR024176 Citrate synthase, bacterial-type SMD11_RS31400 a34422417a8b38ee8081db5495f16556 378 ProSitePatterns PS00480 Citrate synthase signature. 260 272 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SMD11_RS31400 a34422417a8b38ee8081db5495f16556 378 Gene3D G3DSA:1.10.230.10 240 327 1.6E-28 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 SMD11_RS31400 a34422417a8b38ee8081db5495f16556 378 Pfam PF00285 Citrate synthase, C-terminal domain 11 362 7.3E-118 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS21015 9650d1d4c8c45eb2ff22b9d6afe27b42 446 Gene3D G3DSA:3.65.10.10 25 228 1.2E-52 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD11_RS21015 9650d1d4c8c45eb2ff22b9d6afe27b42 446 Gene3D G3DSA:3.65.10.10 229 439 3.7E-48 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD11_RS21015 9650d1d4c8c45eb2ff22b9d6afe27b42 446 SUPERFAMILY SSF55205 7 440 1.36E-112 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SMD11_RS21015 9650d1d4c8c45eb2ff22b9d6afe27b42 446 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 11 431 8.0E-59 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD11_RS21015 9650d1d4c8c45eb2ff22b9d6afe27b42 446 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 7 439 1.4E-131 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS17245 8e5c70ac47f0d3f653dada4cffe444d0 326 SUPERFAMILY SSF52922 192 324 3.66E-38 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS17245 8e5c70ac47f0d3f653dada4cffe444d0 326 Pfam PF02780 Transketolase, C-terminal domain 197 315 1.2E-38 T 06-07-2017 IPR033248 Transketolase, C-terminal domain SMD11_RS17245 8e5c70ac47f0d3f653dada4cffe444d0 326 SUPERFAMILY SSF52518 5 184 3.98E-67 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS17245 8e5c70ac47f0d3f653dada4cffe444d0 326 Gene3D G3DSA:3.40.50.970 4 188 9.5E-75 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS17245 8e5c70ac47f0d3f653dada4cffe444d0 326 SMART SM00861 6 181 8.9E-69 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS17245 8e5c70ac47f0d3f653dada4cffe444d0 326 Pfam PF02779 Transketolase, pyrimidine binding domain 5 180 2.2E-46 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS17245 8e5c70ac47f0d3f653dada4cffe444d0 326 Gene3D G3DSA:3.40.50.920 199 320 1.9E-43 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS27180 53442c2a8b460d5282a1d16eabe6d899 187 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 45.983 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMD11_RS27180 53442c2a8b460d5282a1d16eabe6d899 187 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 155 4.0E-34 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMD11_RS27180 53442c2a8b460d5282a1d16eabe6d899 187 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 06-07-2017 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 SMD11_RS27180 53442c2a8b460d5282a1d16eabe6d899 187 SUPERFAMILY SSF53098 1 156 2.05E-44 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS27180 53442c2a8b460d5282a1d16eabe6d899 187 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 1.6E-36 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMD11_RS27180 53442c2a8b460d5282a1d16eabe6d899 187 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 1.6E-36 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMD11_RS27180 53442c2a8b460d5282a1d16eabe6d899 187 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 1.6E-36 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMD11_RS27180 53442c2a8b460d5282a1d16eabe6d899 187 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 1.6E-36 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMD11_RS27180 53442c2a8b460d5282a1d16eabe6d899 187 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 1.6E-36 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMD11_RS27180 53442c2a8b460d5282a1d16eabe6d899 187 Gene3D G3DSA:3.30.420.10 1 156 8.5E-56 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS27180 53442c2a8b460d5282a1d16eabe6d899 187 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 2.4E-53 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 SMD11_RS03505 265dadcfea81036f36f971f99285b54c 160 SMART SM00344 3 109 1.6E-28 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD11_RS03505 265dadcfea81036f36f971f99285b54c 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 3.0E-13 T 06-07-2017 SMD11_RS03505 265dadcfea81036f36f971f99285b54c 160 Gene3D G3DSA:3.30.70.920 55 146 9.5E-22 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS03505 265dadcfea81036f36f971f99285b54c 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 5.3E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS03505 265dadcfea81036f36f971f99285b54c 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 5.3E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS03505 265dadcfea81036f36f971f99285b54c 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 5.3E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS03505 265dadcfea81036f36f971f99285b54c 160 Gene3D G3DSA:1.10.10.10 2 52 5.1E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03505 265dadcfea81036f36f971f99285b54c 160 SUPERFAMILY SSF46785 3 63 2.51E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03505 265dadcfea81036f36f971f99285b54c 160 SUPERFAMILY SSF54909 64 148 1.1E-19 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS03505 265dadcfea81036f36f971f99285b54c 160 Pfam PF01037 Lrp/AsnC ligand binding domain 69 139 9.9E-19 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS22635 a526c4d22751c834df7b09dcaa83ebe6 250 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 22 242 9.9E-33 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD11_RS22635 a526c4d22751c834df7b09dcaa83ebe6 250 SUPERFAMILY SSF75217 78 249 6.28E-46 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases SMD11_RS22635 a526c4d22751c834df7b09dcaa83ebe6 250 Gene3D G3DSA:3.40.1280.10 16 249 2.8E-68 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMD11_RS22635 a526c4d22751c834df7b09dcaa83ebe6 250 Pfam PF04452 RNA methyltransferase 24 242 1.3E-60 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD11_RS22635 a526c4d22751c834df7b09dcaa83ebe6 250 SUPERFAMILY SSF88697 16 72 4.47E-9 T 06-07-2017 IPR015947 PUA-like domain SMD11_RS22635 a526c4d22751c834df7b09dcaa83ebe6 250 PIRSF PIRSF015601 16 249 1.2E-46 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 SUPERFAMILY SSF52540 19 231 2.7E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 Gene3D G3DSA:3.40.50.300 18 228 2.9E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 SUPERFAMILY SSF52540 459 631 1.2E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 25 433 2.0E-190 T 06-07-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 Gene3D G3DSA:3.40.50.300 443 635 3.1E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 Pfam PF01583 Adenylylsulphate kinase 462 615 7.5E-69 T 06-07-2017 SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 SUPERFAMILY SSF50465 332 433 5.76E-33 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 446 627 2.2E-74 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 Gene3D G3DSA:2.40.30.10 242 363 4.4E-24 T 06-07-2017 SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 461 633 37.284 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 Pfam PF00009 Elongation factor Tu GTP binding domain 24 210 8.2E-40 T 06-07-2017 SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 16 462 51.602 T 06-07-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 SUPERFAMILY SSF50447 241 328 1.31E-23 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 PRINTS PR00315 GTP-binding elongation factor signature 123 134 9.1E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 PRINTS PR00315 GTP-binding elongation factor signature 160 169 9.1E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 PRINTS PR00315 GTP-binding elongation factor signature 87 95 9.1E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 PRINTS PR00315 GTP-binding elongation factor signature 107 117 9.1E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 PRINTS PR00315 GTP-binding elongation factor signature 26 39 9.1E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SMD11_RS08195 4c01f4169909ad777e7d1f14172c990a 635 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 80 95 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site SMD11_RS09300 c6df718bdd1ea9cf522bad9b4259a9f5 423 SUPERFAMILY SSF51735 21 171 2.09E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS09300 c6df718bdd1ea9cf522bad9b4259a9f5 423 SUPERFAMILY SSF69055 313 407 2.62E-24 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMD11_RS09300 c6df718bdd1ea9cf522bad9b4259a9f5 423 Gene3D G3DSA:3.40.50.720 20 171 2.4E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS09300 c6df718bdd1ea9cf522bad9b4259a9f5 423 Pfam PF13288 DXP reductoisomerase C-terminal domain 284 401 3.1E-30 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMD11_RS09300 c6df718bdd1ea9cf522bad9b4259a9f5 423 PIRSF PIRSF006205 21 413 1.2E-140 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMD11_RS09300 c6df718bdd1ea9cf522bad9b4259a9f5 423 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 24 406 43.731 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMD11_RS09300 c6df718bdd1ea9cf522bad9b4259a9f5 423 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 24 155 2.2E-39 T 06-07-2017 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMD11_RS09300 c6df718bdd1ea9cf522bad9b4259a9f5 423 SUPERFAMILY SSF55347 149 285 4.58E-53 T 06-07-2017 SMD11_RS09300 c6df718bdd1ea9cf522bad9b4259a9f5 423 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 167 250 7.2E-36 T 06-07-2017 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMD11_RS09300 c6df718bdd1ea9cf522bad9b4259a9f5 423 Gene3D G3DSA:1.10.1740.10 324 407 2.7E-28 T 06-07-2017 SMD11_RS09300 c6df718bdd1ea9cf522bad9b4259a9f5 423 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 23 409 8.5E-113 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 SMD11_RS06735 638a8264a5b4e04ee065a2391adad05d 247 SUPERFAMILY SSF52540 6 240 1.42E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS06735 638a8264a5b4e04ee065a2391adad05d 247 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS06735 638a8264a5b4e04ee065a2391adad05d 247 PIRSF PIRSF039085 3 246 1.1E-110 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMD11_RS06735 638a8264a5b4e04ee065a2391adad05d 247 SMART SM00382 31 225 2.8E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS06735 638a8264a5b4e04ee065a2391adad05d 247 Gene3D G3DSA:3.40.50.300 5 242 4.9E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS06735 638a8264a5b4e04ee065a2391adad05d 247 Pfam PF00005 ABC transporter 22 170 2.8E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS17150 0f00998c81252d816840848c7ed1a7ac 595 Gene3D G3DSA:3.40.309.10 349 556 1.4E-29 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS17150 0f00998c81252d816840848c7ed1a7ac 595 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 36 595 5.2E-288 T 06-07-2017 IPR011975 Phenylacetic acid degradation protein PaaN2 SMD11_RS17150 0f00998c81252d816840848c7ed1a7ac 595 Pfam PF00171 Aldehyde dehydrogenase family 130 509 1.4E-32 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS17150 0f00998c81252d816840848c7ed1a7ac 595 SUPERFAMILY SSF53720 102 572 3.67E-59 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS17150 0f00998c81252d816840848c7ed1a7ac 595 Gene3D G3DSA:3.40.605.10 121 340 3.6E-28 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS12540 2a8f061ed577ff82722e6f1c509020e4 367 SUPERFAMILY SSF46689 311 357 1.18E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS12540 2a8f061ed577ff82722e6f1c509020e4 367 Gene3D G3DSA:2.60.120.10 116 192 2.6E-8 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS12540 2a8f061ed577ff82722e6f1c509020e4 367 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 312 353 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD11_RS12540 2a8f061ed577ff82722e6f1c509020e4 367 Pfam PF12833 Helix-turn-helix domain 283 359 4.9E-18 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS12540 2a8f061ed577ff82722e6f1c509020e4 367 Pfam PF02311 AraC-like ligand binding domain 134 233 6.0E-5 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD11_RS12540 2a8f061ed577ff82722e6f1c509020e4 367 Gene3D G3DSA:1.10.10.60 313 356 8.6E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS12540 2a8f061ed577ff82722e6f1c509020e4 367 SMART SM00342 275 357 4.0E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS12540 2a8f061ed577ff82722e6f1c509020e4 367 SUPERFAMILY SSF51182 97 192 9.64E-10 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS12540 2a8f061ed577ff82722e6f1c509020e4 367 SUPERFAMILY SSF46689 258 309 5.82E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS12540 2a8f061ed577ff82722e6f1c509020e4 367 Gene3D G3DSA:1.10.10.60 254 312 4.2E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS28615 25cf6eb60d1c9cab67d0f17b7e06cc31 388 Pfam PF00149 Calcineurin-like phosphoesterase 1 95 2.4E-12 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 SMD11_RS28615 25cf6eb60d1c9cab67d0f17b7e06cc31 388 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 267 355 1.2E-8 T 06-07-2017 IPR026843 Nuclease SbcCD subunit D, C-terminal domain SMD11_RS28615 25cf6eb60d1c9cab67d0f17b7e06cc31 388 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 244 2.4E-56 T 06-07-2017 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 SMD11_RS28615 25cf6eb60d1c9cab67d0f17b7e06cc31 388 SUPERFAMILY SSF56300 1 318 5.43E-58 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS28615 25cf6eb60d1c9cab67d0f17b7e06cc31 388 Gene3D G3DSA:3.60.21.10 1 263 3.9E-74 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS25355 d551059c699614140d50fd62b080a6ef 350 Pfam PF00155 Aminotransferase class I and II 24 343 1.9E-30 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS25355 d551059c699614140d50fd62b080a6ef 350 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 202 215 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SMD11_RS25355 d551059c699614140d50fd62b080a6ef 350 Gene3D G3DSA:3.40.640.10 36 244 6.3E-53 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS25355 d551059c699614140d50fd62b080a6ef 350 SUPERFAMILY SSF53383 17 347 8.25E-63 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS25355 d551059c699614140d50fd62b080a6ef 350 Gene3D G3DSA:3.90.1150.10 245 347 1.0E-17 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS21460 6f09fa3e0eb262afc204e335c2d603c5 481 SUPERFAMILY SSF46785 24 90 2.72E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21460 6f09fa3e0eb262afc204e335c2d603c5 481 SUPERFAMILY SSF53067 94 164 4.53E-5 T 06-07-2017 SMD11_RS21460 6f09fa3e0eb262afc204e335c2d603c5 481 Pfam PF00480 ROK family 254 374 2.8E-25 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS21460 6f09fa3e0eb262afc204e335c2d603c5 481 ProSitePatterns PS01125 ROK family signature. 325 352 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS21460 6f09fa3e0eb262afc204e335c2d603c5 481 Gene3D G3DSA:3.30.420.40 330 376 9.1E-19 T 06-07-2017 SMD11_RS21460 6f09fa3e0eb262afc204e335c2d603c5 481 Gene3D G3DSA:3.30.420.40 384 430 1.3E-4 T 06-07-2017 SMD11_RS21460 6f09fa3e0eb262afc204e335c2d603c5 481 SUPERFAMILY SSF53067 255 454 1.35E-27 T 06-07-2017 SMD11_RS21460 6f09fa3e0eb262afc204e335c2d603c5 481 Gene3D G3DSA:1.10.10.10 24 93 4.6E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21460 6f09fa3e0eb262afc204e335c2d603c5 481 Gene3D G3DSA:3.30.420.40 94 156 2.3E-45 T 06-07-2017 SMD11_RS21460 6f09fa3e0eb262afc204e335c2d603c5 481 Gene3D G3DSA:3.30.420.40 253 329 2.3E-45 T 06-07-2017 SMD11_RS12385 dd17912b77d6bea0b2db935403e51780 524 Pfam PF00294 pfkB family carbohydrate kinase 11 87 3.4E-15 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB SMD11_RS12385 dd17912b77d6bea0b2db935403e51780 524 Pfam PF00294 pfkB family carbohydrate kinase 418 474 1.5E-10 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB SMD11_RS12385 dd17912b77d6bea0b2db935403e51780 524 Pfam PF00294 pfkB family carbohydrate kinase 241 376 5.5E-7 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB SMD11_RS12385 dd17912b77d6bea0b2db935403e51780 524 Gene3D G3DSA:3.40.1190.20 416 490 1.7E-88 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS12385 dd17912b77d6bea0b2db935403e51780 524 Gene3D G3DSA:3.40.1190.20 240 371 1.7E-88 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS12385 dd17912b77d6bea0b2db935403e51780 524 Gene3D G3DSA:3.40.1190.20 1 92 1.7E-88 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS12385 dd17912b77d6bea0b2db935403e51780 524 SUPERFAMILY SSF53613 2 85 1.05E-19 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS12385 dd17912b77d6bea0b2db935403e51780 524 SUPERFAMILY SSF53613 240 373 1.15E-33 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS12385 dd17912b77d6bea0b2db935403e51780 524 SUPERFAMILY SSF53613 419 482 1.15E-33 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS16635 584b7a02b6f367f4cb68aca579ba2d8d 73 ProDom PD267558 MEMBRANE TRANSMEMBRANE SPANNING SCO3924 4 36 7.0E-6 T 06-07-2017 IPR020246 Uncharacterised protein family SCO3924 SMD11_RS33825 994b548f8188b91d1e0853fc3fe40978 57 SUPERFAMILY SSF69047 7 56 2.62E-6 T 06-07-2017 IPR008462 CsbD-like SMD11_RS33825 994b548f8188b91d1e0853fc3fe40978 57 Pfam PF05532 CsbD-like 6 57 2.3E-14 T 06-07-2017 IPR008462 CsbD-like SMD11_RS33825 994b548f8188b91d1e0853fc3fe40978 57 Gene3D G3DSA:1.10.1470.10 6 56 8.1E-10 T 06-07-2017 IPR008462 CsbD-like SMD11_RS23680 43710bb1151e0af7feb2e75a787395f8 274 SUPERFAMILY SSF52540 12 246 4.8E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23680 43710bb1151e0af7feb2e75a787395f8 274 Gene3D G3DSA:3.40.50.300 24 248 1.6E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23680 43710bb1151e0af7feb2e75a787395f8 274 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS23680 43710bb1151e0af7feb2e75a787395f8 274 SMART SM00382 47 233 1.4E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS23680 43710bb1151e0af7feb2e75a787395f8 274 Pfam PF00005 ABC transporter 38 185 4.4E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS30450 acc3b816262e309fe5bb70aced5dcaae 339 Gene3D G3DSA:2.80.10.50 221 338 1.1E-28 T 06-07-2017 SMD11_RS30450 acc3b816262e309fe5bb70aced5dcaae 339 SMART SM00458 213 339 9.6E-20 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS30450 acc3b816262e309fe5bb70aced5dcaae 339 Pfam PF00652 Ricin-type beta-trefoil lectin domain 221 336 1.0E-19 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS30450 acc3b816262e309fe5bb70aced5dcaae 339 SUPERFAMILY SSF50370 221 338 4.05E-31 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS16920 c4e4bc952315915ab23bc1cfe8e3ab1f 292 PIRSF PIRSF000103 1 288 1.8E-27 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD11_RS16920 c4e4bc952315915ab23bc1cfe8e3ab1f 292 SUPERFAMILY SSF51735 1 143 7.16E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS16920 c4e4bc952315915ab23bc1cfe8e3ab1f 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 143 4.6E-37 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD11_RS16920 c4e4bc952315915ab23bc1cfe8e3ab1f 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 2.6E-37 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS16920 c4e4bc952315915ab23bc1cfe8e3ab1f 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 149 177 2.6E-37 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS16920 c4e4bc952315915ab23bc1cfe8e3ab1f 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 224 251 2.6E-37 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS16920 c4e4bc952315915ab23bc1cfe8e3ab1f 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 2.6E-37 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS16920 c4e4bc952315915ab23bc1cfe8e3ab1f 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 2.6E-37 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS16920 c4e4bc952315915ab23bc1cfe8e3ab1f 292 Gene3D G3DSA:1.10.1040.10 162 270 1.4E-36 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS16920 c4e4bc952315915ab23bc1cfe8e3ab1f 292 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 160 270 6.5E-27 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS16920 c4e4bc952315915ab23bc1cfe8e3ab1f 292 SUPERFAMILY SSF48179 158 290 3.74E-42 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS16920 c4e4bc952315915ab23bc1cfe8e3ab1f 292 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 291 2.1E-103 T 06-07-2017 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 SMD11_RS16920 c4e4bc952315915ab23bc1cfe8e3ab1f 292 Gene3D G3DSA:3.40.50.720 1 161 1.5E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS16920 c4e4bc952315915ab23bc1cfe8e3ab1f 292 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 228 240 - T 06-07-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS16920 c4e4bc952315915ab23bc1cfe8e3ab1f 292 SMART SM01350 160 287 2.6E-6 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 SMD11_RS11460 681e71baa3d8081fe942eaf3e3426e55 133 SUPERFAMILY SSF54631 1 123 3.79E-29 T 06-07-2017 SMD11_RS11460 681e71baa3d8081fe942eaf3e3426e55 133 SMART SM00116 75 122 2.4E-5 T 06-07-2017 IPR000644 CBS domain SMD11_RS11460 681e71baa3d8081fe942eaf3e3426e55 133 SMART SM00116 10 58 0.022 T 06-07-2017 IPR000644 CBS domain SMD11_RS11460 681e71baa3d8081fe942eaf3e3426e55 133 Pfam PF00571 CBS domain 73 120 1.0E-11 T 06-07-2017 IPR000644 CBS domain SMD11_RS11460 681e71baa3d8081fe942eaf3e3426e55 133 Pfam PF00571 CBS domain 3 55 2.5E-7 T 06-07-2017 IPR000644 CBS domain SMD11_RS11460 681e71baa3d8081fe942eaf3e3426e55 133 Gene3D G3DSA:3.10.580.10 1 122 3.1E-30 T 06-07-2017 SMD11_RS22540 773105d48bd82033e70847ef011757d7 512 SUPERFAMILY SSF54862 442 499 4.71E-5 T 06-07-2017 SMD11_RS22540 773105d48bd82033e70847ef011757d7 512 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 56 217 5.0E-27 T 06-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS22540 773105d48bd82033e70847ef011757d7 512 Gene3D G3DSA:3.30.70.20 443 502 1.3E-5 T 06-07-2017 SMD11_RS22540 773105d48bd82033e70847ef011757d7 512 SUPERFAMILY SSF142984 241 316 6.15E-9 T 06-07-2017 SMD11_RS22540 773105d48bd82033e70847ef011757d7 512 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 329 409 4.6E-17 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS22540 773105d48bd82033e70847ef011757d7 512 SUPERFAMILY SSF140490 322 418 8.76E-18 T 06-07-2017 SMD11_RS22540 773105d48bd82033e70847ef011757d7 512 SUPERFAMILY SSF142019 33 239 1.96E-33 T 06-07-2017 SMD11_RS22540 773105d48bd82033e70847ef011757d7 512 Pfam PF13459 4Fe-4S single cluster domain 444 499 2.1E-9 T 06-07-2017 SMD11_RS22540 773105d48bd82033e70847ef011757d7 512 SMART SM00928 325 369 1.7E-5 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS10095 01c56e98cf3869d6119a36d889305243 541 Gene3D G3DSA:1.25.40.10 115 333 3.1E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS10095 01c56e98cf3869d6119a36d889305243 541 Gene3D G3DSA:1.25.40.10 385 437 3.1E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS10095 01c56e98cf3869d6119a36d889305243 541 Gene3D G3DSA:1.25.40.10 3 35 3.1E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS10095 01c56e98cf3869d6119a36d889305243 541 Gene3D G3DSA:1.10.10.10 464 534 2.8E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS10095 01c56e98cf3869d6119a36d889305243 541 SMART SM00421 472 529 2.4E-25 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS10095 01c56e98cf3869d6119a36d889305243 541 SUPERFAMILY SSF46894 464 535 3.4E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS10095 01c56e98cf3869d6119a36d889305243 541 SUPERFAMILY SSF48452 117 269 4.69E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS10095 01c56e98cf3869d6119a36d889305243 541 Pfam PF00196 Bacterial regulatory proteins, luxR family 475 528 6.2E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS10095 01c56e98cf3869d6119a36d889305243 541 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 475 489 1.1E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS10095 01c56e98cf3869d6119a36d889305243 541 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 489 505 1.1E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS10095 01c56e98cf3869d6119a36d889305243 541 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 505 517 1.1E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS22975 97a2e7eb8ba6cfb0ff902c3ec057a269 305 SUPERFAMILY SSF51735 13 255 9.07E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS22975 97a2e7eb8ba6cfb0ff902c3ec057a269 305 Gene3D G3DSA:3.40.50.720 13 253 3.8E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS22975 97a2e7eb8ba6cfb0ff902c3ec057a269 305 Pfam PF00106 short chain dehydrogenase 16 216 2.0E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS22975 97a2e7eb8ba6cfb0ff902c3ec057a269 305 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 6.9E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS22975 97a2e7eb8ba6cfb0ff902c3ec057a269 305 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 6.9E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS22975 97a2e7eb8ba6cfb0ff902c3ec057a269 305 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 6.9E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS22975 97a2e7eb8ba6cfb0ff902c3ec057a269 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 214 8.3E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS22975 97a2e7eb8ba6cfb0ff902c3ec057a269 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 8.3E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS22975 97a2e7eb8ba6cfb0ff902c3ec057a269 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 8.3E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS22975 97a2e7eb8ba6cfb0ff902c3ec057a269 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 8.3E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28625 fb290b620b47d3e69be567d4c2a3d996 148 SUPERFAMILY SSF46785 7 65 1.58E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28625 fb290b620b47d3e69be567d4c2a3d996 148 Gene3D G3DSA:3.30.70.920 59 133 1.5E-19 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS28625 fb290b620b47d3e69be567d4c2a3d996 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 9.5E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS28625 fb290b620b47d3e69be567d4c2a3d996 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 9.5E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS28625 fb290b620b47d3e69be567d4c2a3d996 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 9.5E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS28625 fb290b620b47d3e69be567d4c2a3d996 148 Pfam PF01037 Lrp/AsnC ligand binding domain 79 138 1.6E-14 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS28625 fb290b620b47d3e69be567d4c2a3d996 148 SMART SM00344 7 112 3.3E-35 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD11_RS28625 fb290b620b47d3e69be567d4c2a3d996 148 Gene3D G3DSA:1.10.10.10 7 58 2.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28625 fb290b620b47d3e69be567d4c2a3d996 148 SUPERFAMILY SSF54909 67 141 5.36E-17 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS28625 fb290b620b47d3e69be567d4c2a3d996 148 ProSitePatterns PS00519 AsnC-type HTH domain signature. 24 50 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMD11_RS28625 fb290b620b47d3e69be567d4c2a3d996 148 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 1.1E-16 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS27945 3c23505cd957b553048257837e3b10ad 225 SMART SM00862 145 220 1.4E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS27945 3c23505cd957b553048257837e3b10ad 225 SUPERFAMILY SSF52172 2 174 1.07E-37 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS27945 3c23505cd957b553048257837e3b10ad 225 Pfam PF00072 Response regulator receiver domain 3 112 2.0E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS27945 3c23505cd957b553048257837e3b10ad 225 SMART SM00448 1 112 5.9E-40 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS27945 3c23505cd957b553048257837e3b10ad 225 Gene3D G3DSA:3.40.50.2300 2 119 6.4E-37 T 06-07-2017 SMD11_RS27945 3c23505cd957b553048257837e3b10ad 225 Gene3D G3DSA:1.10.10.10 126 221 2.0E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27945 3c23505cd957b553048257837e3b10ad 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 219 7.6E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS18285 c309dd08c810540183d104f70ed45ff5 322 Gene3D G3DSA:3.40.190.10 112 204 4.7E-33 T 06-07-2017 SMD11_RS18285 c309dd08c810540183d104f70ed45ff5 322 Gene3D G3DSA:3.30.160.40 226 318 1.8E-22 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18285 c309dd08c810540183d104f70ed45ff5 322 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 9 311 9.5E-88 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18285 c309dd08c810540183d104f70ed45ff5 322 Gene3D G3DSA:3.40.190.10 6 111 6.9E-38 T 06-07-2017 SMD11_RS18285 c309dd08c810540183d104f70ed45ff5 322 SUPERFAMILY SSF53850 7 222 9.51E-65 T 06-07-2017 SMD11_RS18285 c309dd08c810540183d104f70ed45ff5 322 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 9 216 6.2E-66 T 06-07-2017 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18285 c309dd08c810540183d104f70ed45ff5 322 SUPERFAMILY SSF54782 225 319 2.22E-18 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18285 c309dd08c810540183d104f70ed45ff5 322 PIRSF PIRSF001438 1 322 2.3E-109 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18285 c309dd08c810540183d104f70ed45ff5 322 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 232 309 1.4E-16 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18285 c309dd08c810540183d104f70ed45ff5 322 PRINTS PR00151 Porphobilinogen deaminase signature 148 165 1.1E-19 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18285 c309dd08c810540183d104f70ed45ff5 322 PRINTS PR00151 Porphobilinogen deaminase signature 235 252 1.1E-19 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18285 c309dd08c810540183d104f70ed45ff5 322 PRINTS PR00151 Porphobilinogen deaminase signature 46 66 1.1E-19 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18285 c309dd08c810540183d104f70ed45ff5 322 PRINTS PR00151 Porphobilinogen deaminase signature 77 96 1.1E-19 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18285 c309dd08c810540183d104f70ed45ff5 322 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 236 252 - T 06-07-2017 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS18285 c309dd08c810540183d104f70ed45ff5 322 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 8 311 35.116 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS28700 b0a72611e44b8f4c615e02153582744b 388 SUPERFAMILY SSF53067 89 375 4.06E-44 T 06-07-2017 SMD11_RS28700 b0a72611e44b8f4c615e02153582744b 388 Gene3D G3DSA:1.10.10.10 11 84 3.0E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28700 b0a72611e44b8f4c615e02153582744b 388 Pfam PF00480 ROK family 92 370 5.2E-33 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS28700 b0a72611e44b8f4c615e02153582744b 388 Gene3D G3DSA:3.30.420.40 230 349 1.1E-21 T 06-07-2017 SMD11_RS28700 b0a72611e44b8f4c615e02153582744b 388 Gene3D G3DSA:3.30.420.40 87 229 9.0E-39 T 06-07-2017 SMD11_RS28700 b0a72611e44b8f4c615e02153582744b 388 SUPERFAMILY SSF46785 11 75 3.8E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06375 b2a501034aa3f94be64abc65ac426fbd 427 Gene3D G3DSA:3.60.120.10 140 423 3.8E-94 T 06-07-2017 IPR005801 ADC synthase GO:0009058 SMD11_RS06375 b2a501034aa3f94be64abc65ac426fbd 427 SUPERFAMILY SSF56322 81 419 4.97E-94 T 06-07-2017 IPR005801 ADC synthase GO:0009058 SMD11_RS06375 b2a501034aa3f94be64abc65ac426fbd 427 Pfam PF00425 chorismate binding enzyme 157 410 1.4E-76 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal SMD11_RS06375 b2a501034aa3f94be64abc65ac426fbd 427 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 155 417 9.9E-85 T 06-07-2017 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 SMD11_RS28425 9ca1b3cd2775780b1974aa872359ca76 291 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 277 17.614 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SMD11_RS28425 9ca1b3cd2775780b1974aa872359ca76 291 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 270 8.2E-76 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SMD11_RS28425 9ca1b3cd2775780b1974aa872359ca76 291 Pfam PF02673 Bacitracin resistance protein BacA 7 271 9.6E-76 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SMD11_RS11800 98ab6eebadd305a0bfcb4084494d3879 386 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 120 366 6.1E-92 T 06-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein SMD11_RS11800 98ab6eebadd305a0bfcb4084494d3879 386 SUPERFAMILY SSF52540 120 369 4.38E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11800 98ab6eebadd305a0bfcb4084494d3879 386 Hamap MF_02040 Iron-sulfur cluster carrier protein. 111 367 35.054 T 06-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein SMD11_RS11800 98ab6eebadd305a0bfcb4084494d3879 386 Gene3D G3DSA:3.40.50.300 110 365 1.5E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11800 98ab6eebadd305a0bfcb4084494d3879 386 ProSitePatterns PS01215 Mrp family signature. 224 240 - T 06-07-2017 IPR000808 Mrp, conserved site GO:0005524 SMD11_RS11800 98ab6eebadd305a0bfcb4084494d3879 386 SUPERFAMILY SSF117916 11 98 3.27E-23 T 06-07-2017 SMD11_RS11800 98ab6eebadd305a0bfcb4084494d3879 386 Pfam PF01883 Domain of unknown function DUF59 13 86 5.3E-18 T 06-07-2017 IPR002744 Domain of unknown function DUF59 SMD11_RS06840 e82beff523f61af78259d78e85d032b1 277 SUPERFAMILY SSF52540 8 235 2.36E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS06840 e82beff523f61af78259d78e85d032b1 277 Gene3D G3DSA:3.40.50.300 6 241 2.2E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS06840 e82beff523f61af78259d78e85d032b1 277 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS06840 e82beff523f61af78259d78e85d032b1 277 Pfam PF00005 ABC transporter 24 178 1.6E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS06840 e82beff523f61af78259d78e85d032b1 277 SMART SM00382 33 226 2.9E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS12955 eb8d13b1e69462089da0554c35713888 460 Gene3D G3DSA:1.20.1250.20 243 404 1.0E-9 T 06-07-2017 SMD11_RS12955 eb8d13b1e69462089da0554c35713888 460 Gene3D G3DSA:1.20.1250.20 26 208 1.3E-17 T 06-07-2017 SMD11_RS12955 eb8d13b1e69462089da0554c35713888 460 SUPERFAMILY SSF103473 12 410 6.8E-40 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS12955 eb8d13b1e69462089da0554c35713888 460 Pfam PF07690 Major Facilitator Superfamily 35 372 2.5E-27 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS12955 eb8d13b1e69462089da0554c35713888 460 ProSitePatterns PS00216 Sugar transport proteins signature 1. 80 96 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS29795 6f8c836814cb7d14af9e70f10470926f 109 ProDom PD012644 CYCLASE POLYKETIDE II SYNTHESIS ORF SYNTHASE JADI BIOSYNTHESIS ANTIBIOTIC CYCLASE-LIKE 2 107 2.0E-52 T 06-07-2017 IPR006765 Polyketide synthesis cyclase GO:0030639 SMD11_RS29795 6f8c836814cb7d14af9e70f10470926f 109 Gene3D G3DSA:3.30.70.1090 1 107 5.4E-47 T 06-07-2017 IPR006765 Polyketide synthesis cyclase GO:0030639 SMD11_RS29795 6f8c836814cb7d14af9e70f10470926f 109 SUPERFAMILY SSF54909 1 107 7.51E-45 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS29795 6f8c836814cb7d14af9e70f10470926f 109 Pfam PF04673 Polyketide synthesis cyclase 2 106 2.4E-43 T 06-07-2017 IPR006765 Polyketide synthesis cyclase GO:0030639 SMD11_RS08820 2b134aa42c425c5ecbdddf556ada6b7e 659 SMART SM00487 20 310 7.3E-5 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS08820 2b134aa42c425c5ecbdddf556ada6b7e 659 Gene3D G3DSA:3.40.50.300 192 264 2.5E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08820 2b134aa42c425c5ecbdddf556ada6b7e 659 Gene3D G3DSA:3.40.50.300 397 406 2.5E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08820 2b134aa42c425c5ecbdddf556ada6b7e 659 Gene3D G3DSA:3.40.50.300 25 118 2.5E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08820 2b134aa42c425c5ecbdddf556ada6b7e 659 Pfam PF13307 Helicase C-terminal domain 474 632 2.0E-26 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 SMD11_RS08820 2b134aa42c425c5ecbdddf556ada6b7e 659 SUPERFAMILY SSF52540 38 88 1.74E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08820 2b134aa42c425c5ecbdddf556ada6b7e 659 SUPERFAMILY SSF52540 192 263 1.74E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08820 2b134aa42c425c5ecbdddf556ada6b7e 659 SUPERFAMILY SSF52540 395 409 1.74E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08820 2b134aa42c425c5ecbdddf556ada6b7e 659 SUPERFAMILY SSF52540 448 603 1.74E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08820 2b134aa42c425c5ecbdddf556ada6b7e 659 SMART SM00491 491 620 7.1E-41 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 SMD11_RS08820 2b134aa42c425c5ecbdddf556ada6b7e 659 Gene3D G3DSA:3.40.50.300 466 613 3.1E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21275 56f16bc1921fab59ceace0b128f94900 274 SUPERFAMILY SSF54060 241 270 5.18E-5 T 06-07-2017 SMD11_RS21275 56f16bc1921fab59ceace0b128f94900 274 Pfam PF13392 HNH endonuclease 241 264 3.0E-6 T 06-07-2017 IPR003615 HNH nuclease SMD11_RS09865 ae2c19c7bc1b23b9ef08fd73d53a5fc3 260 SUPERFAMILY SSF56529 53 257 1.7E-79 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD11_RS09865 ae2c19c7bc1b23b9ef08fd73d53a5fc3 260 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 62 256 1.0E-67 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD11_RS09865 ae2c19c7bc1b23b9ef08fd73d53a5fc3 260 Gene3D G3DSA:3.90.850.10 53 258 1.1E-90 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD11_RS09865 ae2c19c7bc1b23b9ef08fd73d53a5fc3 260 Pfam PF10370 Domain of unknown function (DUF2437) 2 57 5.1E-13 T 06-07-2017 IPR018833 Domain of unknown function DUF2437 SMD11_RS22220 e261a4bcc62252edb258d0ce9dbeb08a 212 SUPERFAMILY SSF46609 3 89 3.27E-30 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD11_RS22220 e261a4bcc62252edb258d0ce9dbeb08a 212 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 4 83 7.4E-30 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD11_RS22220 e261a4bcc62252edb258d0ce9dbeb08a 212 PIRSF PIRSF000349 1 208 7.2E-71 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD11_RS22220 e261a4bcc62252edb258d0ce9dbeb08a 212 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 06-07-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD11_RS22220 e261a4bcc62252edb258d0ce9dbeb08a 212 Gene3D G3DSA:1.10.287.990 21 84 5.4E-22 T 06-07-2017 SMD11_RS22220 e261a4bcc62252edb258d0ce9dbeb08a 212 SUPERFAMILY SSF54719 98 204 2.62E-37 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD11_RS22220 e261a4bcc62252edb258d0ce9dbeb08a 212 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 3.1E-19 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD11_RS22220 e261a4bcc62252edb258d0ce9dbeb08a 212 PRINTS PR01703 Manganese superoxide dismutase signature 125 133 3.1E-19 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD11_RS22220 e261a4bcc62252edb258d0ce9dbeb08a 212 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 3.1E-19 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD11_RS22220 e261a4bcc62252edb258d0ce9dbeb08a 212 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 3.1E-19 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD11_RS22220 e261a4bcc62252edb258d0ce9dbeb08a 212 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 3.1E-19 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD11_RS22220 e261a4bcc62252edb258d0ce9dbeb08a 212 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 98 198 3.7E-32 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD11_RS15040 484b9f8e582d63a080ea05f1b2893a89 404 Gene3D G3DSA:3.30.1220.10 247 376 1.3E-8 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD11_RS15040 484b9f8e582d63a080ea05f1b2893a89 404 SUPERFAMILY SSF90002 260 323 6.41E-10 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD11_RS15040 484b9f8e582d63a080ea05f1b2893a89 404 SUPERFAMILY SSF90002 350 376 6.41E-10 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD11_RS15040 484b9f8e582d63a080ea05f1b2893a89 404 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 261 376 5.1E-19 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD11_RS15040 484b9f8e582d63a080ea05f1b2893a89 404 Gene3D G3DSA:3.40.50.300 66 175 1.8E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15040 484b9f8e582d63a080ea05f1b2893a89 404 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 66 174 4.3E-6 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain SMD11_RS15040 484b9f8e582d63a080ea05f1b2893a89 404 SMART SM00833 260 376 7.5E-38 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD11_RS17145 ba77ee5a238325b393558fe72618dcc6 252 SUPERFAMILY SSF75217 98 246 1.26E-28 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases SMD11_RS17145 ba77ee5a238325b393558fe72618dcc6 252 Pfam PF00588 SpoU rRNA Methylase family 114 243 8.8E-24 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SMD11_RS17145 ba77ee5a238325b393558fe72618dcc6 252 Gene3D G3DSA:3.30.1330.30 21 96 5.1E-4 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like SMD11_RS17145 ba77ee5a238325b393558fe72618dcc6 252 Gene3D G3DSA:3.40.1280.10 112 246 2.6E-26 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMD11_RS12775 d13cc2a529e88d64dc441caaf5fd071d 292 Gene3D G3DSA:1.10.260.40 4 74 1.2E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS12775 d13cc2a529e88d64dc441caaf5fd071d 292 Pfam PF13560 Helix-turn-helix domain 13 69 1.4E-8 T 06-07-2017 SMD11_RS12775 d13cc2a529e88d64dc441caaf5fd071d 292 SUPERFAMILY SSF47413 12 75 3.94E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS12775 d13cc2a529e88d64dc441caaf5fd071d 292 SMART SM00530 17 72 1.9E-4 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS29890 49a5c93274242da128b2924887bb5276 224 SMART SM00382 32 197 2.4E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS29890 49a5c93274242da128b2924887bb5276 224 Gene3D G3DSA:3.40.50.300 4 196 1.9E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29890 49a5c93274242da128b2924887bb5276 224 SUPERFAMILY SSF52540 6 198 3.42E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29890 49a5c93274242da128b2924887bb5276 224 Pfam PF00005 ABC transporter 23 151 2.2E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS02310 e084670796ffe5bba76b258799d8f633 301 Gene3D G3DSA:1.10.1660.10 11 115 5.4E-27 T 06-07-2017 SMD11_RS02310 e084670796ffe5bba76b258799d8f633 301 Pfam PF13411 MerR HTH family regulatory protein 11 77 1.9E-15 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS02310 e084670796ffe5bba76b258799d8f633 301 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 22 35 1.3E-5 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS02310 e084670796ffe5bba76b258799d8f633 301 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 1.3E-5 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS02310 e084670796ffe5bba76b258799d8f633 301 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 11 22 1.3E-5 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS02310 e084670796ffe5bba76b258799d8f633 301 SUPERFAMILY SSF46955 11 115 5.13E-24 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS02310 e084670796ffe5bba76b258799d8f633 301 SMART SM00422 10 79 9.9E-21 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS20100 a3cae49ae99d848dbe19c273063c09aa 602 SUPERFAMILY SSF52540 5 208 3.69E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20100 a3cae49ae99d848dbe19c273063c09aa 602 Gene3D G3DSA:3.40.50.300 288 492 1.8E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20100 a3cae49ae99d848dbe19c273063c09aa 602 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS20100 a3cae49ae99d848dbe19c273063c09aa 602 Pfam PF12848 ABC transporter 198 265 1.4E-7 T 06-07-2017 IPR032781 ABC-transporter extension domain SMD11_RS20100 a3cae49ae99d848dbe19c273063c09aa 602 SUPERFAMILY SSF52540 279 492 6.13E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20100 a3cae49ae99d848dbe19c273063c09aa 602 Gene3D G3DSA:3.40.50.300 7 251 1.1E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20100 a3cae49ae99d848dbe19c273063c09aa 602 SMART SM00382 315 491 5.9E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS20100 a3cae49ae99d848dbe19c273063c09aa 602 SMART SM00382 30 213 7.4E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS20100 a3cae49ae99d848dbe19c273063c09aa 602 Pfam PF16326 ABC transporter C-terminal domain 539 600 4.2E-8 T 06-07-2017 IPR032524 ABC transporter Uup, C-terminal GO:0003677 SMD11_RS20100 a3cae49ae99d848dbe19c273063c09aa 602 Pfam PF00005 ABC transporter 307 447 7.6E-20 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS20100 a3cae49ae99d848dbe19c273063c09aa 602 Pfam PF00005 ABC transporter 21 159 6.1E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS20100 a3cae49ae99d848dbe19c273063c09aa 602 ProSitePatterns PS00211 ABC transporters family signature. 419 433 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS26010 73ad9c590e62b071d10ceb704161cde2 153 ProSitePatterns PS00999 Streptomyces subtilisin-type inhibitors signature. 74 92 - T 06-07-2017 IPR020054 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor, conserved site GO:0004867 SMD11_RS26010 73ad9c590e62b071d10ceb704161cde2 153 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 128 144 3.4E-28 T 06-07-2017 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD11_RS26010 73ad9c590e62b071d10ceb704161cde2 153 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 48 74 3.4E-28 T 06-07-2017 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD11_RS26010 73ad9c590e62b071d10ceb704161cde2 153 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 111 127 3.4E-28 T 06-07-2017 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD11_RS26010 73ad9c590e62b071d10ceb704161cde2 153 Gene3D G3DSA:3.30.350.10 47 153 8.7E-36 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 SMD11_RS26010 73ad9c590e62b071d10ceb704161cde2 153 Pfam PF00720 Subtilisin inhibitor-like 47 139 5.8E-35 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 SMD11_RS26010 73ad9c590e62b071d10ceb704161cde2 153 Hamap MF_00778 Probable subtilase-type protease inhibitor [sti]. 46 153 32.566 T 06-07-2017 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 SMD11_RS26010 73ad9c590e62b071d10ceb704161cde2 153 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 51 141 3.0E-47 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 SMD11_RS26010 73ad9c590e62b071d10ceb704161cde2 153 SUPERFAMILY SSF55399 46 153 4.45E-41 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 SMD11_RS03335 30797aefc30a3a08058a1a2ac86ffa16 667 Gene3D G3DSA:3.50.50.60 541 649 1.7E-72 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03335 30797aefc30a3a08058a1a2ac86ffa16 667 Gene3D G3DSA:3.50.50.60 143 325 1.7E-72 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03335 30797aefc30a3a08058a1a2ac86ffa16 667 SUPERFAMILY SSF51905 154 377 5.74E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03335 30797aefc30a3a08058a1a2ac86ffa16 667 SUPERFAMILY SSF51905 457 551 5.74E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03335 30797aefc30a3a08058a1a2ac86ffa16 667 Pfam PF00743 Flavin-binding monooxygenase-like 153 355 2.8E-20 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 SMD11_RS03335 30797aefc30a3a08058a1a2ac86ffa16 667 Gene3D G3DSA:3.50.50.60 326 372 1.0E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03335 30797aefc30a3a08058a1a2ac86ffa16 667 Gene3D G3DSA:3.50.50.60 446 508 1.0E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03335 30797aefc30a3a08058a1a2ac86ffa16 667 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 321 346 1.6E-5 T 06-07-2017 SMD11_RS03335 30797aefc30a3a08058a1a2ac86ffa16 667 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 175 1.6E-5 T 06-07-2017 SMD11_RS28800 ec5291b76d098500713994fb58115a6a 156 Gene3D G3DSA:3.90.1720.10 37 146 1.4E-38 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS28800 ec5291b76d098500713994fb58115a6a 156 SUPERFAMILY SSF54001 41 146 9.32E-36 T 06-07-2017 SMD11_RS28800 ec5291b76d098500713994fb58115a6a 156 Pfam PF00877 NlpC/P60 family 55 139 6.2E-25 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS01855 7d6e6eaf0e65bc608c694474d51f418f 133 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 99 1.9E-9 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS01855 7d6e6eaf0e65bc608c694474d51f418f 133 Gene3D G3DSA:3.90.470.20 5 122 2.8E-23 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS01855 7d6e6eaf0e65bc608c694474d51f418f 133 SUPERFAMILY SSF56214 5 123 7.33E-16 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS01855 7d6e6eaf0e65bc608c694474d51f418f 133 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 121 3.0E-6 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SMD11_RS01855 7d6e6eaf0e65bc608c694474d51f418f 133 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 126 17.112 T 06-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SMD11_RS01855 7d6e6eaf0e65bc608c694474d51f418f 133 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 5 120 8.5E-15 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SMD11_RS23165 77d4c09a35d8837ae15e43db38c3edb8 302 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 69 284 8.8E-21 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS23165 77d4c09a35d8837ae15e43db38c3edb8 302 Gene3D G3DSA:3.40.50.1110 233 295 4.9E-23 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS23165 77d4c09a35d8837ae15e43db38c3edb8 302 Gene3D G3DSA:3.40.50.1110 63 197 4.9E-23 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS23165 77d4c09a35d8837ae15e43db38c3edb8 302 SUPERFAMILY SSF52266 237 295 2.83E-26 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS23165 77d4c09a35d8837ae15e43db38c3edb8 302 SUPERFAMILY SSF52266 62 198 2.83E-26 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS17300 68640d92f3c9458ec04d72426e4e1c9c 609 Gene3D G3DSA:2.40.110.10 161 272 2.7E-24 T 06-07-2017 SMD11_RS17300 68640d92f3c9458ec04d72426e4e1c9c 609 Gene3D G3DSA:1.20.140.10 273 466 7.6E-42 T 06-07-2017 SMD11_RS17300 68640d92f3c9458ec04d72426e4e1c9c 609 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 471 605 1.3E-30 T 06-07-2017 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain SMD11_RS17300 68640d92f3c9458ec04d72426e4e1c9c 609 SUPERFAMILY SSF56645 37 283 2.23E-41 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS17300 68640d92f3c9458ec04d72426e4e1c9c 609 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 286 452 1.7E-15 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS17300 68640d92f3c9458ec04d72426e4e1c9c 609 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 6.0E-11 T 06-07-2017 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria SMD11_RS17300 68640d92f3c9458ec04d72426e4e1c9c 609 Gene3D G3DSA:1.10.540.10 36 147 6.6E-6 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS17300 68640d92f3c9458ec04d72426e4e1c9c 609 SUPERFAMILY SSF47203 290 475 7.89E-32 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS17300 68640d92f3c9458ec04d72426e4e1c9c 609 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 272 1.1E-17 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS18675 c5fdcb6809f6f90f346bb9aceec1bd1b 441 Pfam PF07730 Histidine kinase 253 317 1.3E-13 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS18675 c5fdcb6809f6f90f346bb9aceec1bd1b 441 Gene3D G3DSA:3.30.565.10 358 439 2.7E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS18675 c5fdcb6809f6f90f346bb9aceec1bd1b 441 SUPERFAMILY SSF55874 332 439 4.24E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS18675 c5fdcb6809f6f90f346bb9aceec1bd1b 441 Pfam PF13796 Putative sensor 34 225 5.8E-44 T 06-07-2017 IPR025828 Putative sensor domain SMD11_RS14610 016d1f480e55e69b447b4f98e13806d9 336 Gene3D G3DSA:1.10.530.10 50 193 1.4E-30 T 06-07-2017 SMD11_RS14610 016d1f480e55e69b447b4f98e13806d9 336 Pfam PF01464 Transglycosylase SLT domain 67 165 8.4E-14 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 SMD11_RS14610 016d1f480e55e69b447b4f98e13806d9 336 SUPERFAMILY SSF54001 196 322 7.36E-34 T 06-07-2017 SMD11_RS14610 016d1f480e55e69b447b4f98e13806d9 336 Pfam PF00877 NlpC/P60 family 214 307 1.7E-22 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS14610 016d1f480e55e69b447b4f98e13806d9 336 Gene3D G3DSA:3.90.1720.10 195 323 3.9E-36 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS14610 016d1f480e55e69b447b4f98e13806d9 336 SUPERFAMILY SSF53955 50 188 2.64E-30 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS18510 c95535275aa5e6272f84e4c039832bd8 232 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 229 6.1E-72 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 SMD11_RS18510 c95535275aa5e6272f84e4c039832bd8 232 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 229 5.2E-60 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 SMD11_RS18510 c95535275aa5e6272f84e4c039832bd8 232 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 137 151 - T 06-07-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 SMD11_RS18510 c95535275aa5e6272f84e4c039832bd8 232 Gene3D G3DSA:3.40.50.150 12 225 2.8E-45 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS18510 c95535275aa5e6272f84e4c039832bd8 232 SUPERFAMILY SSF53335 4 229 7.35E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS18510 c95535275aa5e6272f84e4c039832bd8 232 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 229 34.463 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 SMD11_RS28835 d877484ab24a8bf9470a4ed2b86a0af3 559 Gene3D G3DSA:3.40.50.1820 99 187 7.4E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28835 d877484ab24a8bf9470a4ed2b86a0af3 559 Gene3D G3DSA:3.40.50.1820 231 357 7.4E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28835 d877484ab24a8bf9470a4ed2b86a0af3 559 Gene3D G3DSA:3.40.50.1820 413 533 7.4E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28835 d877484ab24a8bf9470a4ed2b86a0af3 559 Pfam PF00561 alpha/beta hydrolase fold 135 513 3.9E-28 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS28835 d877484ab24a8bf9470a4ed2b86a0af3 559 SUPERFAMILY SSF53474 133 188 4.18E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28835 d877484ab24a8bf9470a4ed2b86a0af3 559 SUPERFAMILY SSF53474 233 287 4.18E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28835 d877484ab24a8bf9470a4ed2b86a0af3 559 SUPERFAMILY SSF53474 410 517 4.18E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS02945 38a7003496b5089328b12789c1b42773 89 SUPERFAMILY SSF143212 3 84 4.18E-23 T 06-07-2017 SMD11_RS02945 38a7003496b5089328b12789c1b42773 89 Pfam PF08962 Domain of unknown function (DUF1876) 6 86 9.4E-28 T 06-07-2017 IPR015057 Protein of unknown function DUF1876 SMD11_RS02945 38a7003496b5089328b12789c1b42773 89 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 3 56 5.0E-9 T 06-07-2017 IPR015057 Protein of unknown function DUF1876 SMD11_RS16105 c1453d7d3ca42253df54e78731d78f6b 265 SUPERFAMILY SSF46689 35 95 3.23E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS16105 c1453d7d3ca42253df54e78731d78f6b 265 SUPERFAMILY SSF48498 102 256 2.11E-25 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS16105 c1453d7d3ca42253df54e78731d78f6b 265 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 102 253 3.8E-15 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD11_RS16105 c1453d7d3ca42253df54e78731d78f6b 265 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 85 1.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS16105 c1453d7d3ca42253df54e78731d78f6b 265 Gene3D G3DSA:1.10.357.10 31 258 4.3E-58 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS02825 6e68e88649ab3983b404d4b5bbfbd037 246 Pfam PF12802 MarR family 106 165 3.5E-10 T 06-07-2017 SMD11_RS02825 6e68e88649ab3983b404d4b5bbfbd037 246 Pfam PF13936 Helix-turn-helix domain 3 45 5.1E-15 T 06-07-2017 IPR025246 Transposase IS30-like HTH domain SMD11_RS02825 6e68e88649ab3983b404d4b5bbfbd037 246 Gene3D G3DSA:1.10.10.10 88 169 4.4E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02825 6e68e88649ab3983b404d4b5bbfbd037 246 SUPERFAMILY SSF46785 90 169 2.97E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS29830 ad94513a9a639b0771323e8836a60d2d 481 Gene3D G3DSA:1.20.1250.20 280 473 7.5E-14 T 06-07-2017 SMD11_RS29830 ad94513a9a639b0771323e8836a60d2d 481 Pfam PF07690 Major Facilitator Superfamily 34 424 1.6E-49 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS29830 ad94513a9a639b0771323e8836a60d2d 481 SUPERFAMILY SSF103473 263 475 1.29E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS29830 ad94513a9a639b0771323e8836a60d2d 481 SUPERFAMILY SSF103473 12 209 1.29E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS29830 ad94513a9a639b0771323e8836a60d2d 481 Gene3D G3DSA:1.20.1250.20 23 205 3.7E-28 T 06-07-2017 SMD11_RS05030 aba07e4c97fd4307f0f6361fb910fd60 289 SUPERFAMILY SSF52402 3 143 5.78E-28 T 06-07-2017 SMD11_RS05030 aba07e4c97fd4307f0f6361fb910fd60 289 Pfam PF00582 Universal stress protein family 3 139 5.4E-24 T 06-07-2017 IPR006016 UspA GO:0006950 SMD11_RS05030 aba07e4c97fd4307f0f6361fb910fd60 289 Pfam PF00582 Universal stress protein family 148 287 1.2E-19 T 06-07-2017 IPR006016 UspA GO:0006950 SMD11_RS05030 aba07e4c97fd4307f0f6361fb910fd60 289 Gene3D G3DSA:3.40.50.620 145 287 4.2E-26 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS05030 aba07e4c97fd4307f0f6361fb910fd60 289 Gene3D G3DSA:3.40.50.620 1 139 7.1E-29 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS05030 aba07e4c97fd4307f0f6361fb910fd60 289 PRINTS PR01438 Universal stress protein signature 2 20 2.0E-14 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS05030 aba07e4c97fd4307f0f6361fb910fd60 289 PRINTS PR01438 Universal stress protein signature 99 111 2.0E-14 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS05030 aba07e4c97fd4307f0f6361fb910fd60 289 PRINTS PR01438 Universal stress protein signature 117 139 2.0E-14 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS05030 aba07e4c97fd4307f0f6361fb910fd60 289 SUPERFAMILY SSF52402 150 288 3.93E-22 T 06-07-2017 SMD11_RS27850 66e346115a122f7543ad05a72846e2f2 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 6.8E-16 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS27850 66e346115a122f7543ad05a72846e2f2 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 6.8E-16 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS27850 66e346115a122f7543ad05a72846e2f2 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 6.8E-16 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS27850 66e346115a122f7543ad05a72846e2f2 147 Gene3D G3DSA:3.30.70.920 54 133 7.5E-25 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS27850 66e346115a122f7543ad05a72846e2f2 147 Pfam PF01037 Lrp/AsnC ligand binding domain 67 137 2.1E-16 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS27850 66e346115a122f7543ad05a72846e2f2 147 SUPERFAMILY SSF54909 61 143 6.44E-16 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS27850 66e346115a122f7543ad05a72846e2f2 147 SMART SM00344 3 108 5.0E-45 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD11_RS27850 66e346115a122f7543ad05a72846e2f2 147 SUPERFAMILY SSF46785 2 60 2.85E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27850 66e346115a122f7543ad05a72846e2f2 147 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMD11_RS27850 66e346115a122f7543ad05a72846e2f2 147 Gene3D G3DSA:1.10.10.10 3 53 1.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27850 66e346115a122f7543ad05a72846e2f2 147 Pfam PF13404 AsnC-type helix-turn-helix domain 3 42 1.0E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS10835 88944df1d9cc537ebfb17d095f7243c8 219 Gene3D G3DSA:3.40.50.270 21 134 1.8E-31 T 06-07-2017 SMD11_RS10835 88944df1d9cc537ebfb17d095f7243c8 219 Gene3D G3DSA:3.40.50.270 175 212 1.8E-31 T 06-07-2017 SMD11_RS10835 88944df1d9cc537ebfb17d095f7243c8 219 SUPERFAMILY SSF52788 182 211 9.68E-23 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD11_RS10835 88944df1d9cc537ebfb17d095f7243c8 219 SUPERFAMILY SSF52788 19 143 9.68E-23 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD11_RS10835 88944df1d9cc537ebfb17d095f7243c8 219 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 23 153 9.9E-16 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD11_RS10835 88944df1d9cc537ebfb17d095f7243c8 219 SMART SM00226 21 211 1.0E-6 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD11_RS25725 a075f60a218bd0ede6802377d5d2643e 290 Gene3D G3DSA:2.40.30.10 17 147 4.0E-33 T 06-07-2017 SMD11_RS25725 a075f60a218bd0ede6802377d5d2643e 290 Pfam PF08021 Siderophore-interacting FAD-binding domain 25 149 1.3E-35 T 06-07-2017 IPR013113 FAD-binding 9, siderophore-interacting SMD11_RS25725 a075f60a218bd0ede6802377d5d2643e 290 SUPERFAMILY SSF63380 13 147 1.79E-11 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD11_RS25725 a075f60a218bd0ede6802377d5d2643e 290 Gene3D G3DSA:3.40.50.80 158 284 1.4E-48 T 06-07-2017 SMD11_RS25725 a075f60a218bd0ede6802377d5d2643e 290 Pfam PF04954 Siderophore-interacting protein 164 279 3.4E-39 T 06-07-2017 IPR007037 Siderophore-interacting protein SMD11_RS15860 9a3ac02a0a10c81b36b0c0c216dc3b9f 420 SUPERFAMILY SSF56059 90 313 1.33E-22 T 06-07-2017 SMD11_RS15860 9a3ac02a0a10c81b36b0c0c216dc3b9f 420 Gene3D G3DSA:3.30.1490.20 106 173 2.6E-14 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS16755 82aa61ea62ad19a1fb8404749d5a8496 446 Pfam PF01554 MatE 243 394 3.6E-19 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SMD11_RS16755 82aa61ea62ad19a1fb8404749d5a8496 446 Pfam PF01554 MatE 25 184 7.8E-28 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SMD11_RS16755 82aa61ea62ad19a1fb8404749d5a8496 446 PIRSF PIRSF006603 12 445 1.6E-62 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SMD11_RS16755 82aa61ea62ad19a1fb8404749d5a8496 446 TIGRFAM TIGR00797 matE: MATE efflux family protein 25 415 1.7E-102 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SMD11_RS34395 3b5778d55a166b4ad8142826965c0f06 249 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 1 231 1.8E-8 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS34395 3b5778d55a166b4ad8142826965c0f06 249 Gene3D G3DSA:3.60.10.10 81 238 7.8E-12 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS34395 3b5778d55a166b4ad8142826965c0f06 249 SUPERFAMILY SSF56219 1 134 1.26E-22 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS34395 3b5778d55a166b4ad8142826965c0f06 249 SUPERFAMILY SSF56219 166 235 1.26E-22 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS31195 f22e553cf21376ae57cda2adad12fbe9 315 SUPERFAMILY SSF50486 204 308 3.92E-19 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 SMD11_RS31195 f22e553cf21376ae57cda2adad12fbe9 315 Pfam PF00551 Formyl transferase 1 169 1.9E-32 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS31195 f22e553cf21376ae57cda2adad12fbe9 315 Gene3D G3DSA:3.10.25.10 206 306 1.4E-19 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS31195 f22e553cf21376ae57cda2adad12fbe9 315 Pfam PF02911 Formyl transferase, C-terminal domain 204 305 1.5E-16 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS31195 f22e553cf21376ae57cda2adad12fbe9 315 SUPERFAMILY SSF53328 1 204 3.14E-57 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS31195 f22e553cf21376ae57cda2adad12fbe9 315 Gene3D G3DSA:3.40.50.170 1 203 1.7E-54 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS16060 d23f62bb2f82f6647a923bea6d5e7e49 116 Gene3D G3DSA:3.30.750.24 12 114 1.7E-18 T 06-07-2017 IPR002645 STAS domain SMD11_RS16060 d23f62bb2f82f6647a923bea6d5e7e49 116 Pfam PF01740 STAS domain 16 113 1.2E-9 T 06-07-2017 IPR002645 STAS domain SMD11_RS16060 d23f62bb2f82f6647a923bea6d5e7e49 116 SUPERFAMILY SSF52091 10 114 7.85E-15 T 06-07-2017 IPR002645 STAS domain SMD11_RS01870 d3aa320aa5c5a273f1653fcb51bf83d4 316 SUPERFAMILY SSF53901 11 313 4.19E-27 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS01870 d3aa320aa5c5a273f1653fcb51bf83d4 316 Gene3D G3DSA:3.40.47.10 8 168 9.5E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS01870 d3aa320aa5c5a273f1653fcb51bf83d4 316 Gene3D G3DSA:3.40.47.10 169 311 9.9E-21 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS01870 d3aa320aa5c5a273f1653fcb51bf83d4 316 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 224 312 5.7E-15 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS23890 bc258c82f46a5ce3228c91136cf3de80 290 Gene3D G3DSA:1.10.3720.10 17 277 2.2E-68 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS23890 bc258c82f46a5ce3228c91136cf3de80 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 283 3.3E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS23890 bc258c82f46a5ce3228c91136cf3de80 290 SUPERFAMILY SSF161098 20 290 1.19E-69 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS16865 dee7b5fc9d706eb5de1d94d6ac899ef3 366 Gene3D G3DSA:3.90.1530.10 84 184 3.6E-37 T 06-07-2017 SMD11_RS16865 dee7b5fc9d706eb5de1d94d6ac899ef3 366 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 87 263 4.6E-60 T 06-07-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 SMD11_RS16865 dee7b5fc9d706eb5de1d94d6ac899ef3 366 Pfam PF02195 ParB-like nuclease domain 89 177 1.1E-24 T 06-07-2017 IPR003115 ParB/Sulfiredoxin SMD11_RS16865 dee7b5fc9d706eb5de1d94d6ac899ef3 366 SUPERFAMILY SSF109709 170 280 1.11E-33 T 06-07-2017 SMD11_RS16865 dee7b5fc9d706eb5de1d94d6ac899ef3 366 SUPERFAMILY SSF110849 89 180 1.46E-26 T 06-07-2017 IPR003115 ParB/Sulfiredoxin SMD11_RS16865 dee7b5fc9d706eb5de1d94d6ac899ef3 366 SMART SM00470 88 178 8.7E-34 T 06-07-2017 IPR003115 ParB/Sulfiredoxin SMD11_RS09110 4e90930189507858f4dfa9ae0d664f1a 95 SUPERFAMILY SSF47060 3 89 2.15E-35 T 06-07-2017 IPR009068 S15/NS1, RNA-binding SMD11_RS09110 4e90930189507858f4dfa9ae0d664f1a 95 SMART SM01387 8 88 1.1E-52 T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS09110 4e90930189507858f4dfa9ae0d664f1a 95 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 4.0E-38 T 06-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09110 4e90930189507858f4dfa9ae0d664f1a 95 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.292 T 06-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09110 4e90930189507858f4dfa9ae0d664f1a 95 Gene3D G3DSA:1.10.287.10 3 89 9.9E-40 T 06-07-2017 IPR009068 S15/NS1, RNA-binding SMD11_RS09110 4e90930189507858f4dfa9ae0d664f1a 95 Pfam PF00312 Ribosomal protein S15 8 88 9.4E-38 T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS09110 4e90930189507858f4dfa9ae0d664f1a 95 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 5.0E-23 T 06-07-2017 SMD11_RS09110 4e90930189507858f4dfa9ae0d664f1a 95 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18265 458e99f10b76b3448b7aef8c7c5d16cf 318 Gene3D G3DSA:3.40.50.1000 140 284 1.8E-47 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS18265 458e99f10b76b3448b7aef8c7c5d16cf 318 SUPERFAMILY SSF56784 67 276 3.34E-28 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS18265 458e99f10b76b3448b7aef8c7c5d16cf 318 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 67 257 1.4E-15 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 SMD11_RS18265 458e99f10b76b3448b7aef8c7c5d16cf 318 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 67 268 6.5E-52 T 06-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial SMD11_RS18265 458e99f10b76b3448b7aef8c7c5d16cf 318 Pfam PF12710 haloacid dehalogenase-like hydrolase 68 254 1.8E-26 T 06-07-2017 SMD11_RS18020 f9a0baa1db7b8c488e03fc004c58bcc4 67 SUPERFAMILY SSF50249 1 66 5.14E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS18020 f9a0baa1db7b8c488e03fc004c58bcc4 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site SMD11_RS18020 f9a0baa1db7b8c488e03fc004c58bcc4 67 SMART SM00357 3 67 6.2E-30 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 SMD11_RS18020 f9a0baa1db7b8c488e03fc004c58bcc4 67 Gene3D G3DSA:2.40.50.140 1 65 2.5E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS18020 f9a0baa1db7b8c488e03fc004c58bcc4 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.3E-29 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS18020 f9a0baa1db7b8c488e03fc004c58bcc4 67 PIRSF PIRSF002599 1 67 3.6E-25 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 SMD11_RS18020 f9a0baa1db7b8c488e03fc004c58bcc4 67 PRINTS PR00050 Cold shock protein signature 25 34 3.0E-17 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS18020 f9a0baa1db7b8c488e03fc004c58bcc4 67 PRINTS PR00050 Cold shock protein signature 40 58 3.0E-17 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS18020 f9a0baa1db7b8c488e03fc004c58bcc4 67 PRINTS PR00050 Cold shock protein signature 4 19 3.0E-17 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS29020 980b372c8651348d44d5a7097749f34e 251 PIRSF PIRSF006648 2 249 9.4E-35 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS29020 980b372c8651348d44d5a7097749f34e 251 Pfam PF01061 ABC-2 type transporter 4 212 1.2E-28 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD11_RS28120 6234189bae2b57216f3c4932ee883376 149 Gene3D G3DSA:2.70.70.10 3 148 1.2E-44 T 06-07-2017 SMD11_RS28120 6234189bae2b57216f3c4932ee883376 149 SUPERFAMILY SSF51261 3 146 9.59E-36 T 06-07-2017 IPR011055 Duplicated hybrid motif SMD11_RS28120 6234189bae2b57216f3c4932ee883376 149 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 3 124 8.2E-38 T 06-07-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SMD11_RS03380 ac4cd6fa2fea94a4cf598b6d1f8101f5 390 PIRSF PIRSF016578 5 390 3.2E-132 T 06-07-2017 SMD11_RS03380 ac4cd6fa2fea94a4cf598b6d1f8101f5 390 SUPERFAMILY SSF47203 244 370 4.76E-11 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS03380 ac4cd6fa2fea94a4cf598b6d1f8101f5 390 Gene3D G3DSA:1.10.540.10 8 123 4.2E-26 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS03380 ac4cd6fa2fea94a4cf598b6d1f8101f5 390 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 244 375 1.8E-29 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain SMD11_RS03380 ac4cd6fa2fea94a4cf598b6d1f8101f5 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 32 97 3.0E-4 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS03380 ac4cd6fa2fea94a4cf598b6d1f8101f5 390 Gene3D G3DSA:1.20.140.10 210 388 3.0E-31 T 06-07-2017 SMD11_RS03380 ac4cd6fa2fea94a4cf598b6d1f8101f5 390 Gene3D G3DSA:2.40.110.10 126 209 1.1E-26 T 06-07-2017 SMD11_RS03380 ac4cd6fa2fea94a4cf598b6d1f8101f5 390 SUPERFAMILY SSF56645 24 215 1.7E-30 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS26030 d7c6275b3db8cffc675f497785986654 578 SMART SM00382 357 551 3.9E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS26030 d7c6275b3db8cffc675f497785986654 578 SMART SM00382 27 233 2.8E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS26030 d7c6275b3db8cffc675f497785986654 578 SUPERFAMILY SSF52540 1 247 1.55E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26030 d7c6275b3db8cffc675f497785986654 578 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS26030 d7c6275b3db8cffc675f497785986654 578 Gene3D G3DSA:3.40.50.300 323 575 5.9E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26030 d7c6275b3db8cffc675f497785986654 578 Gene3D G3DSA:3.40.50.300 1 249 7.1E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26030 d7c6275b3db8cffc675f497785986654 578 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS26030 d7c6275b3db8cffc675f497785986654 578 SUPERFAMILY SSF52540 327 573 2.66E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26030 d7c6275b3db8cffc675f497785986654 578 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 553 576 0.038 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS26030 d7c6275b3db8cffc675f497785986654 578 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 227 259 1.3E-5 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS26030 d7c6275b3db8cffc675f497785986654 578 Pfam PF00005 ABC transporter 349 501 3.7E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS26030 d7c6275b3db8cffc675f497785986654 578 Pfam PF00005 ABC transporter 19 175 1.9E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS33580 99ceeeed20d9e5eafaefed97c056772c 253 Gene3D G3DSA:3.40.50.720 3 252 1.4E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33580 99ceeeed20d9e5eafaefed97c056772c 253 SUPERFAMILY SSF51735 9 252 1.55E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33580 99ceeeed20d9e5eafaefed97c056772c 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 251 3.6E-59 T 06-07-2017 SMD11_RS33580 99ceeeed20d9e5eafaefed97c056772c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33580 99ceeeed20d9e5eafaefed97c056772c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33580 99ceeeed20d9e5eafaefed97c056772c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33580 99ceeeed20d9e5eafaefed97c056772c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33580 99ceeeed20d9e5eafaefed97c056772c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33580 99ceeeed20d9e5eafaefed97c056772c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33580 99ceeeed20d9e5eafaefed97c056772c 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 197 0.0055 T 06-07-2017 SMD11_RS33580 99ceeeed20d9e5eafaefed97c056772c 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 8.2E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33580 99ceeeed20d9e5eafaefed97c056772c 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 8.2E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33580 99ceeeed20d9e5eafaefed97c056772c 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 8.2E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33580 99ceeeed20d9e5eafaefed97c056772c 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS14235 84dd148d1504b2f15af832c2b739fb54 755 SUPERFAMILY SSF143724 176 372 2.94E-66 T 06-07-2017 SMD11_RS14235 84dd148d1504b2f15af832c2b739fb54 755 Pfam PF02503 Polyphosphate kinase middle domain 188 378 5.5E-67 T 06-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 SMD11_RS14235 84dd148d1504b2f15af832c2b739fb54 755 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 72 743 2.1E-251 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 SMD11_RS14235 84dd148d1504b2f15af832c2b739fb54 755 Pfam PF13090 Polyphosphate kinase C-terminal domain 394 742 4.7E-153 T 06-07-2017 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 SMD11_RS14235 84dd148d1504b2f15af832c2b739fb54 755 Pfam PF13089 Polyphosphate kinase N-terminal domain 73 179 6.3E-37 T 06-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 SMD11_RS14235 84dd148d1504b2f15af832c2b739fb54 755 Gene3D G3DSA:3.30.1840.10 175 360 1.6E-73 T 06-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 SMD11_RS14235 84dd148d1504b2f15af832c2b739fb54 755 SUPERFAMILY SSF140356 70 174 2.49E-35 T 06-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 SMD11_RS14235 84dd148d1504b2f15af832c2b739fb54 755 SUPERFAMILY SSF56024 565 747 1.68E-64 T 06-07-2017 SMD11_RS14235 84dd148d1504b2f15af832c2b739fb54 755 PIRSF PIRSF015589 58 754 1.6E-283 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 SMD11_RS14235 84dd148d1504b2f15af832c2b739fb54 755 Gene3D G3DSA:3.30.870.10 565 747 3.2E-70 T 06-07-2017 SMD11_RS14235 84dd148d1504b2f15af832c2b739fb54 755 SUPERFAMILY SSF56024 390 562 3.14E-56 T 06-07-2017 SMD11_RS14235 84dd148d1504b2f15af832c2b739fb54 755 Hamap MF_00347 Polyphosphate kinase [ppk]. 70 746 34.179 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 SMD11_RS14235 84dd148d1504b2f15af832c2b739fb54 755 Gene3D G3DSA:3.30.870.10 389 564 4.0E-79 T 06-07-2017 SMD11_RS28630 3f9e7dcb36f034547ba44b4be899568d 148 SMART SM00450 23 122 2.3E-14 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS28630 3f9e7dcb36f034547ba44b4be899568d 148 Gene3D G3DSA:3.40.250.10 20 126 4.3E-22 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS28630 3f9e7dcb36f034547ba44b4be899568d 148 SUPERFAMILY SSF52821 13 125 1.7E-25 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS28630 3f9e7dcb36f034547ba44b4be899568d 148 Pfam PF00581 Rhodanese-like domain 27 118 4.9E-13 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS12645 ae75878ad4729d7c3123dfad13ddf6b9 346 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 33 47 6.5E-8 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS12645 ae75878ad4729d7c3123dfad13ddf6b9 346 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 47 65 6.5E-8 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS12645 ae75878ad4729d7c3123dfad13ddf6b9 346 Gene3D G3DSA:3.40.50.1360 86 236 1.4E-13 T 06-07-2017 SMD11_RS12645 ae75878ad4729d7c3123dfad13ddf6b9 346 SUPERFAMILY SSF100950 85 244 3.24E-29 T 06-07-2017 SMD11_RS12645 ae75878ad4729d7c3123dfad13ddf6b9 346 Gene3D G3DSA:1.10.10.10 14 65 1.1E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12645 ae75878ad4729d7c3123dfad13ddf6b9 346 ProSitePatterns PS00894 DeoR-type HTH domain signature. 15 49 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMD11_RS12645 ae75878ad4729d7c3123dfad13ddf6b9 346 SUPERFAMILY SSF46785 14 68 2.34E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12645 ae75878ad4729d7c3123dfad13ddf6b9 346 Pfam PF08220 DeoR-like helix-turn-helix domain 15 67 2.5E-14 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS12645 ae75878ad4729d7c3123dfad13ddf6b9 346 SMART SM01134 82 243 6.4E-65 T 06-07-2017 SMD11_RS12645 ae75878ad4729d7c3123dfad13ddf6b9 346 SMART SM00420 15 67 2.8E-14 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS12645 ae75878ad4729d7c3123dfad13ddf6b9 346 Pfam PF00455 DeoR C terminal sensor domain 85 242 8.0E-50 T 06-07-2017 IPR014036 DeoR C-terminal sensor domain SMD11_RS28775 b52aad10ac62da4769103bb41f452725 411 TIGRFAM TIGR00433 bioB: biotin synthase 28 321 1.7E-112 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMD11_RS28775 b52aad10ac62da4769103bb41f452725 411 Pfam PF04055 Radical SAM superfamily 65 220 1.8E-11 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS28775 b52aad10ac62da4769103bb41f452725 411 SUPERFAMILY SSF102114 18 321 2.75E-74 T 06-07-2017 SMD11_RS28775 b52aad10ac62da4769103bb41f452725 411 Gene3D G3DSA:3.20.20.70 17 322 4.9E-87 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS28775 b52aad10ac62da4769103bb41f452725 411 Hamap MF_01694 Biotin synthase [bioB]. 15 323 39.312 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMD11_RS28775 b52aad10ac62da4769103bb41f452725 411 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 232 321 8.6E-15 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMD11_RS28775 b52aad10ac62da4769103bb41f452725 411 SMART SM00729 55 261 8.9E-35 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD11_RS28775 b52aad10ac62da4769103bb41f452725 411 SMART SM00876 232 322 3.5E-33 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 SMD11_RS06905 d2499ba4aa6420d35fd8ed26b8075395 449 SUPERFAMILY SSF51556 60 375 1.87E-95 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS06905 d2499ba4aa6420d35fd8ed26b8075395 449 Pfam PF01979 Amidohydrolase family 57 429 8.1E-24 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 SMD11_RS06905 d2499ba4aa6420d35fd8ed26b8075395 449 Gene3D G3DSA:3.20.20.140 74 396 1.1E-127 T 06-07-2017 SMD11_RS06905 d2499ba4aa6420d35fd8ed26b8075395 449 Gene3D G3DSA:2.30.40.10 8 73 1.1E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS06905 d2499ba4aa6420d35fd8ed26b8075395 449 TIGRFAM TIGR03178 allantoinase: allantoinase 7 444 8.2E-178 T 06-07-2017 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 SMD11_RS06905 d2499ba4aa6420d35fd8ed26b8075395 449 SUPERFAMILY SSF51338 7 59 1.36E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS06905 d2499ba4aa6420d35fd8ed26b8075395 449 SUPERFAMILY SSF51338 375 434 1.36E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS34070 f2f75e33c0088f05667341b7cd48f9e4 695 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 301 344 8.7E-9 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS34070 f2f75e33c0088f05667341b7cd48f9e4 695 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 44 237 8.0E-80 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS34070 f2f75e33c0088f05667341b7cd48f9e4 695 Gene3D G3DSA:3.40.50.970 301 362 3.2E-41 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS34070 f2f75e33c0088f05667341b7cd48f9e4 695 Gene3D G3DSA:3.40.50.970 43 230 3.2E-41 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS34070 f2f75e33c0088f05667341b7cd48f9e4 695 SUPERFAMILY SSF52922 563 682 4.32E-23 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS34070 f2f75e33c0088f05667341b7cd48f9e4 695 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 43 685 39.325 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS34070 f2f75e33c0088f05667341b7cd48f9e4 695 ProSitePatterns PS00802 Transketolase signature 2. 487 503 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS34070 f2f75e33c0088f05667341b7cd48f9e4 695 Gene3D G3DSA:3.40.50.920 564 681 7.4E-24 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS34070 f2f75e33c0088f05667341b7cd48f9e4 695 SMART SM00861 381 546 7.4E-55 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS34070 f2f75e33c0088f05667341b7cd48f9e4 695 Pfam PF02780 Transketolase, C-terminal domain 561 676 7.3E-21 T 06-07-2017 IPR033248 Transketolase, C-terminal domain SMD11_RS34070 f2f75e33c0088f05667341b7cd48f9e4 695 Pfam PF02779 Transketolase, pyrimidine binding domain 381 543 1.8E-38 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS34070 f2f75e33c0088f05667341b7cd48f9e4 695 SUPERFAMILY SSF52518 42 234 7.79E-61 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS34070 f2f75e33c0088f05667341b7cd48f9e4 695 SUPERFAMILY SSF52518 305 443 7.79E-61 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS34070 f2f75e33c0088f05667341b7cd48f9e4 695 Gene3D G3DSA:3.40.50.970 363 543 5.1E-59 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS24610 42f3dc2b26b15b73104da2163cfef0bf 273 SUPERFAMILY SSF52833 80 263 8.54E-20 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS24610 42f3dc2b26b15b73104da2163cfef0bf 273 Pfam PF13462 Thioredoxin 82 252 3.3E-32 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS24610 42f3dc2b26b15b73104da2163cfef0bf 273 Gene3D G3DSA:3.40.30.10 84 269 3.4E-25 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS32840 51256443a9812eb9c1eab5b8a0aaab7d 397 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 6 392 3.5E-190 T 06-07-2017 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 SMD11_RS32840 51256443a9812eb9c1eab5b8a0aaab7d 397 SUPERFAMILY SSF53383 9 393 2.39E-114 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS32840 51256443a9812eb9c1eab5b8a0aaab7d 397 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 396 53.883 T 06-07-2017 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 SMD11_RS32840 51256443a9812eb9c1eab5b8a0aaab7d 397 Gene3D G3DSA:3.90.1150.10 280 392 7.7E-29 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS32840 51256443a9812eb9c1eab5b8a0aaab7d 397 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 242 251 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMD11_RS32840 51256443a9812eb9c1eab5b8a0aaab7d 397 Gene3D G3DSA:3.40.640.10 64 279 1.4E-87 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS32840 51256443a9812eb9c1eab5b8a0aaab7d 397 Pfam PF00155 Aminotransferase class I and II 46 387 1.4E-68 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS04355 9d05d18e8b402b5253a0cc8a7ebf16e3 419 PIRSF PIRSF036428 2 406 1.4E-148 T 06-07-2017 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 SMD11_RS04355 9d05d18e8b402b5253a0cc8a7ebf16e3 419 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 192 1.5E-22 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS04355 9d05d18e8b402b5253a0cc8a7ebf16e3 419 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 8 197 4.2E-50 T 06-07-2017 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 SMD11_RS04355 9d05d18e8b402b5253a0cc8a7ebf16e3 419 Gene3D G3DSA:3.30.950.10 112 212 1.4E-28 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS04355 9d05d18e8b402b5253a0cc8a7ebf16e3 419 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 235 356 4.7E-31 T 06-07-2017 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 SMD11_RS04355 9d05d18e8b402b5253a0cc8a7ebf16e3 419 Gene3D G3DSA:3.40.50.150 236 405 1.8E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS04355 9d05d18e8b402b5253a0cc8a7ebf16e3 419 SUPERFAMILY SSF53790 6 209 1.44E-41 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS04355 9d05d18e8b402b5253a0cc8a7ebf16e3 419 SUPERFAMILY SSF53335 208 400 1.17E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS04355 9d05d18e8b402b5253a0cc8a7ebf16e3 419 Gene3D G3DSA:3.40.1010.10 6 111 1.2E-28 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS06480 a58050ad56d8809ffa623f0b0719a765 619 Gene3D G3DSA:3.40.50.720 335 521 5.3E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06480 a58050ad56d8809ffa623f0b0719a765 619 Gene3D G3DSA:3.40.50.720 25 211 3.3E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06480 a58050ad56d8809ffa623f0b0719a765 619 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 340 517 3.6E-56 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS06480 a58050ad56d8809ffa623f0b0719a765 619 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 29 207 6.8E-58 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS06480 a58050ad56d8809ffa623f0b0719a765 619 SUPERFAMILY SSF51735 336 517 1.76E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06480 a58050ad56d8809ffa623f0b0719a765 619 SUPERFAMILY SSF51735 26 209 1.39E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06480 a58050ad56d8809ffa623f0b0719a765 619 SUPERFAMILY SSF48179 520 617 3.74E-29 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS06480 a58050ad56d8809ffa623f0b0719a765 619 Gene3D G3DSA:1.10.1040.10 212 307 1.3E-28 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS06480 a58050ad56d8809ffa623f0b0719a765 619 Gene3D G3DSA:1.10.1040.10 522 616 4.4E-32 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS06480 a58050ad56d8809ffa623f0b0719a765 619 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 210 306 2.9E-28 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS06480 a58050ad56d8809ffa623f0b0719a765 619 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 520 616 3.4E-33 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS06480 a58050ad56d8809ffa623f0b0719a765 619 SUPERFAMILY SSF48179 209 313 3.57E-28 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS01265 109feda75c1a06790b85f7ea2b2aca65 345 Gene3D G3DSA:3.30.470.20 126 136 6.1E-40 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS01265 109feda75c1a06790b85f7ea2b2aca65 345 Gene3D G3DSA:3.30.470.20 217 343 6.1E-40 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS01265 109feda75c1a06790b85f7ea2b2aca65 345 Pfam PF07478 D-ala D-ala ligase C-terminus 162 340 1.6E-37 T 06-07-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS01265 109feda75c1a06790b85f7ea2b2aca65 345 SUPERFAMILY SSF52440 1 135 9.59E-24 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS01265 109feda75c1a06790b85f7ea2b2aca65 345 Gene3D G3DSA:3.30.1490.20 137 216 2.4E-7 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS01265 109feda75c1a06790b85f7ea2b2aca65 345 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 286 314 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS01265 109feda75c1a06790b85f7ea2b2aca65 345 Gene3D G3DSA:3.40.50.20 2 125 6.0E-24 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS01265 109feda75c1a06790b85f7ea2b2aca65 345 SUPERFAMILY SSF56059 137 340 3.53E-41 T 06-07-2017 SMD11_RS01265 109feda75c1a06790b85f7ea2b2aca65 345 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 1 344 27.633 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS01265 109feda75c1a06790b85f7ea2b2aca65 345 PIRSF PIRSF039102 1 345 3.9E-68 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS01265 109feda75c1a06790b85f7ea2b2aca65 345 Pfam PF01820 D-ala D-ala ligase N-terminus 3 126 6.1E-21 T 06-07-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS01265 109feda75c1a06790b85f7ea2b2aca65 345 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 103 114 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS26635 4ed361f5586912bb531993af429bca54 307 Gene3D G3DSA:3.40.190.10 189 274 1.6E-19 T 06-07-2017 SMD11_RS26635 4ed361f5586912bb531993af429bca54 307 Pfam PF03466 LysR substrate binding domain 103 301 1.7E-45 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS26635 4ed361f5586912bb531993af429bca54 307 SUPERFAMILY SSF53850 104 303 1.92E-40 T 06-07-2017 SMD11_RS26635 4ed361f5586912bb531993af429bca54 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 4.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS26635 4ed361f5586912bb531993af429bca54 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 4.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS26635 4ed361f5586912bb531993af429bca54 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 4.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS26635 4ed361f5586912bb531993af429bca54 307 Gene3D G3DSA:3.40.190.10 105 188 4.2E-15 T 06-07-2017 SMD11_RS26635 4ed361f5586912bb531993af429bca54 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 74 5.6E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS26635 4ed361f5586912bb531993af429bca54 307 SUPERFAMILY SSF46785 12 123 4.87E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26635 4ed361f5586912bb531993af429bca54 307 Gene3D G3DSA:1.10.10.10 15 99 2.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27605 ef5d196757195b1cd6328383f5116333 669 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 383 666 9.4E-34 T 06-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SMD11_RS27605 ef5d196757195b1cd6328383f5116333 669 Gene3D G3DSA:3.30.1490.20 320 348 6.9E-48 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS27605 ef5d196757195b1cd6328383f5116333 669 Gene3D G3DSA:3.30.1490.20 395 551 6.9E-48 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS27605 ef5d196757195b1cd6328383f5116333 669 SUPERFAMILY SSF56059 374 667 2.59E-40 T 06-07-2017 SMD11_RS27605 ef5d196757195b1cd6328383f5116333 669 Gene3D G3DSA:3.30.470.20 552 666 1.0E-8 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS06595 80275cef4cd1cd7a97e4f680e4d6a122 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 45 65 1.8E-22 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS06595 80275cef4cd1cd7a97e4f680e4d6a122 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 94 110 1.8E-22 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS06595 80275cef4cd1cd7a97e4f680e4d6a122 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 143 166 1.8E-22 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS06595 80275cef4cd1cd7a97e4f680e4d6a122 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 187 208 1.8E-22 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS06595 80275cef4cd1cd7a97e4f680e4d6a122 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 218 242 1.8E-22 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS06595 80275cef4cd1cd7a97e4f680e4d6a122 275 Pfam PF00459 Inositol monophosphatase family 15 247 1.0E-53 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS06595 80275cef4cd1cd7a97e4f680e4d6a122 275 Gene3D G3DSA:3.30.540.10 14 159 1.8E-35 T 06-07-2017 SMD11_RS06595 80275cef4cd1cd7a97e4f680e4d6a122 275 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 221 235 - T 06-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 SMD11_RS06595 80275cef4cd1cd7a97e4f680e4d6a122 275 SUPERFAMILY SSF56655 17 271 2.75E-58 T 06-07-2017 SMD11_RS06595 80275cef4cd1cd7a97e4f680e4d6a122 275 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 94 107 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site SMD11_RS06595 80275cef4cd1cd7a97e4f680e4d6a122 275 Gene3D G3DSA:3.40.190.80 174 271 1.5E-15 T 06-07-2017 SMD11_RS07630 5d5661e6499e65ee6c8c5ab849ae50bb 75 Pfam PF12728 Helix-turn-helix domain 18 68 3.2E-13 T 06-07-2017 SMD11_RS07630 5d5661e6499e65ee6c8c5ab849ae50bb 75 Gene3D G3DSA:1.10.10.10 17 71 1.7E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07630 5d5661e6499e65ee6c8c5ab849ae50bb 75 SUPERFAMILY SSF46955 17 69 7.32E-10 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS08715 ac815ec6051bcb1e9b55644da4bb838f 312 Gene3D G3DSA:1.10.10.10 77 147 1.5E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08715 ac815ec6051bcb1e9b55644da4bb838f 312 SUPERFAMILY SSF48008 171 297 9.94E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS08715 ac815ec6051bcb1e9b55644da4bb838f 312 SMART SM00895 174 298 1.0E-21 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS08715 ac815ec6051bcb1e9b55644da4bb838f 312 SUPERFAMILY SSF46785 79 149 4.5E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08715 ac815ec6051bcb1e9b55644da4bb838f 312 Pfam PF00392 Bacterial regulatory proteins, gntR family 86 145 2.5E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS08715 ac815ec6051bcb1e9b55644da4bb838f 312 SMART SM00345 87 145 1.1E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS08715 ac815ec6051bcb1e9b55644da4bb838f 312 Pfam PF07729 FCD domain 174 297 5.8E-22 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS08715 ac815ec6051bcb1e9b55644da4bb838f 312 Gene3D G3DSA:1.20.120.530 170 297 5.1E-24 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS07385 8b98cbec9a759c6ec10b7cd54095a560 647 Gene3D G3DSA:3.40.710.10 245 645 2.8E-83 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS07385 8b98cbec9a759c6ec10b7cd54095a560 647 SUPERFAMILY SSF53955 56 263 7.31E-63 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS07385 8b98cbec9a759c6ec10b7cd54095a560 647 Pfam PF00912 Transglycosylase 69 243 1.1E-55 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 SMD11_RS07385 8b98cbec9a759c6ec10b7cd54095a560 647 Pfam PF00905 Penicillin binding protein transpeptidase domain 349 597 4.4E-16 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD11_RS07385 8b98cbec9a759c6ec10b7cd54095a560 647 Gene3D G3DSA:1.10.3810.10 68 244 4.6E-60 T 06-07-2017 SMD11_RS07385 8b98cbec9a759c6ec10b7cd54095a560 647 SUPERFAMILY SSF56601 227 247 3.58E-66 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS07385 8b98cbec9a759c6ec10b7cd54095a560 647 SUPERFAMILY SSF56601 277 646 3.58E-66 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS24265 802ff8ee3ba9e18fe798f8bb00069d73 361 SUPERFAMILY SSF54001 243 351 2.84E-38 T 06-07-2017 SMD11_RS24265 802ff8ee3ba9e18fe798f8bb00069d73 361 Pfam PF00877 NlpC/P60 family 260 351 1.5E-25 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS24265 802ff8ee3ba9e18fe798f8bb00069d73 361 Gene3D G3DSA:3.90.1720.10 243 350 1.0E-40 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS15015 3ca4e57bb0f8d854df18935f3205025a 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS15015 3ca4e57bb0f8d854df18935f3205025a 485 Pfam PF00171 Aldehyde dehydrogenase family 24 474 5.0E-156 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS15015 3ca4e57bb0f8d854df18935f3205025a 485 SUPERFAMILY SSF53720 10 479 2.62E-151 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS15015 3ca4e57bb0f8d854df18935f3205025a 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS15015 3ca4e57bb0f8d854df18935f3205025a 485 Gene3D G3DSA:3.40.605.10 11 267 5.3E-79 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS15015 3ca4e57bb0f8d854df18935f3205025a 485 Gene3D G3DSA:3.40.309.10 268 450 1.3E-64 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS29935 8e985cf81eed774fe42816cdd22b8871 225 SUPERFAMILY SSF51219 32 217 3.66E-45 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMD11_RS29935 8e985cf81eed774fe42816cdd22b8871 225 Gene3D G3DSA:3.60.160.10 33 218 3.4E-40 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 SMD11_RS29935 8e985cf81eed774fe42816cdd22b8871 225 Pfam PF01987 Mitochondrial biogenesis AIM24 33 214 1.8E-32 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 SMD11_RS32415 0530d38192a7d45fe06cfccd53766f53 495 Gene3D G3DSA:3.40.50.1820 37 267 8.0E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32415 0530d38192a7d45fe06cfccd53766f53 495 Gene3D G3DSA:3.40.50.1820 345 472 8.0E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32415 0530d38192a7d45fe06cfccd53766f53 495 Pfam PF00561 alpha/beta hydrolase fold 74 214 1.8E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS32415 0530d38192a7d45fe06cfccd53766f53 495 SUPERFAMILY SSF53474 60 122 2.66E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32415 0530d38192a7d45fe06cfccd53766f53 495 SUPERFAMILY SSF53474 153 207 2.66E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32415 0530d38192a7d45fe06cfccd53766f53 495 SUPERFAMILY SSF53474 337 471 2.66E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32415 0530d38192a7d45fe06cfccd53766f53 495 Pfam PF08386 TAP-like protein 393 481 1.5E-13 T 06-07-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMD11_RS14170 643369f3ea0bec979d7eb0c479cd1a89 226 SUPERFAMILY SSF52172 3 123 6.83E-41 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS14170 643369f3ea0bec979d7eb0c479cd1a89 226 SUPERFAMILY SSF46894 125 225 1.87E-31 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS14170 643369f3ea0bec979d7eb0c479cd1a89 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 1.3E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS14170 643369f3ea0bec979d7eb0c479cd1a89 226 SMART SM00448 2 112 1.7E-44 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS14170 643369f3ea0bec979d7eb0c479cd1a89 226 SMART SM00862 148 224 7.5E-30 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS14170 643369f3ea0bec979d7eb0c479cd1a89 226 Gene3D G3DSA:3.40.50.2300 3 121 6.9E-40 T 06-07-2017 SMD11_RS14170 643369f3ea0bec979d7eb0c479cd1a89 226 Gene3D G3DSA:1.10.10.10 127 225 4.9E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14170 643369f3ea0bec979d7eb0c479cd1a89 226 Pfam PF00072 Response regulator receiver domain 4 113 7.1E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 Gene3D G3DSA:3.40.50.1260 1 175 9.1E-64 T 06-07-2017 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 403 40.144 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 PRINTS PR00477 Phosphoglycerate kinase family signature 11 27 8.5E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 PRINTS PR00477 Phosphoglycerate kinase family signature 322 347 8.5E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 PRINTS PR00477 Phosphoglycerate kinase family signature 355 366 8.5E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 PRINTS PR00477 Phosphoglycerate kinase family signature 172 194 8.5E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 PRINTS PR00477 Phosphoglycerate kinase family signature 142 164 8.5E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 PRINTS PR00477 Phosphoglycerate kinase family signature 32 54 8.5E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 PRINTS PR00477 Phosphoglycerate kinase family signature 379 396 8.5E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 8.5E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 PRINTS PR00477 Phosphoglycerate kinase family signature 195 214 8.5E-80 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 Gene3D G3DSA:3.40.50.1270 183 391 6.3E-77 T 06-07-2017 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 SUPERFAMILY SSF53748 5 403 9.07E-139 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 PIRSF PIRSF000724 1 403 6.4E-130 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 16 26 - T 06-07-2017 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25125 508405534e04a126c2ba1b4ef73c8381 403 Pfam PF00162 Phosphoglycerate kinase 12 393 2.5E-144 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS18555 19d8d2641a44abe6aa73876a64238f18 274 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 22 164 2.6E-43 T 06-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18555 19d8d2641a44abe6aa73876a64238f18 274 SUPERFAMILY SSF52833 21 173 1.08E-47 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS18555 19d8d2641a44abe6aa73876a64238f18 274 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 22 164 4.5E-49 T 06-07-2017 SMD11_RS18555 19d8d2641a44abe6aa73876a64238f18 274 Gene3D G3DSA:3.40.30.10 85 169 2.3E-8 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS04235 4eb7df411473b296781a19b1183c6a5e 404 SUPERFAMILY SSF48264 17 403 4.71E-102 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS04235 4eb7df411473b296781a19b1183c6a5e 404 Gene3D G3DSA:1.10.630.10 17 404 6.8E-133 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS04235 4eb7df411473b296781a19b1183c6a5e 404 Pfam PF00067 Cytochrome P450 207 269 5.8E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS04235 4eb7df411473b296781a19b1183c6a5e 404 Pfam PF00067 Cytochrome P450 277 373 5.9E-17 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS04235 4eb7df411473b296781a19b1183c6a5e 404 PRINTS PR00359 B-class P450 signature 155 170 1.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04235 4eb7df411473b296781a19b1183c6a5e 404 PRINTS PR00359 B-class P450 signature 193 215 1.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04235 4eb7df411473b296781a19b1183c6a5e 404 PRINTS PR00359 B-class P450 signature 322 337 1.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04235 4eb7df411473b296781a19b1183c6a5e 404 PRINTS PR00359 B-class P450 signature 92 103 1.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04235 4eb7df411473b296781a19b1183c6a5e 404 PRINTS PR00359 B-class P450 signature 276 287 1.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04235 4eb7df411473b296781a19b1183c6a5e 404 PRINTS PR00359 B-class P450 signature 352 363 1.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04235 4eb7df411473b296781a19b1183c6a5e 404 PRINTS PR00359 B-class P450 signature 343 352 1.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04235 4eb7df411473b296781a19b1183c6a5e 404 PRINTS PR00359 B-class P450 signature 294 321 1.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04235 4eb7df411473b296781a19b1183c6a5e 404 PRINTS PR00359 B-class P450 signature 138 154 1.1E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20405 efb16af3815a64b38cdbd92dd8f4138a 106 Gene3D G3DSA:1.10.10.10 2 87 3.4E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20405 efb16af3815a64b38cdbd92dd8f4138a 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 3.0E-11 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS20405 efb16af3815a64b38cdbd92dd8f4138a 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 1 16 3.0E-11 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS20405 efb16af3815a64b38cdbd92dd8f4138a 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 34 49 3.0E-11 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS20405 efb16af3815a64b38cdbd92dd8f4138a 106 SUPERFAMILY SSF46785 2 78 5.45E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20405 efb16af3815a64b38cdbd92dd8f4138a 106 SMART SM00418 1 78 2.0E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS20405 efb16af3815a64b38cdbd92dd8f4138a 106 Pfam PF12840 Helix-turn-helix domain 2 58 2.8E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02460 e83fa28dbbf1b8867c5320f4be8330d1 352 Gene3D G3DSA:1.10.10.10 20 105 7.7E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02460 e83fa28dbbf1b8867c5320f4be8330d1 352 Pfam PF00891 O-methyltransferase 111 331 1.4E-51 T 06-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 SMD11_RS02460 e83fa28dbbf1b8867c5320f4be8330d1 352 PIRSF PIRSF005739 8 347 1.1E-47 T 06-07-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 SMD11_RS02460 e83fa28dbbf1b8867c5320f4be8330d1 352 Gene3D G3DSA:3.40.50.150 106 350 6.1E-68 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS02460 e83fa28dbbf1b8867c5320f4be8330d1 352 Pfam PF16864 Dimerisation domain 21 100 1.4E-10 T 06-07-2017 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain SMD11_RS02460 e83fa28dbbf1b8867c5320f4be8330d1 352 SUPERFAMILY SSF46785 20 101 8.62E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02460 e83fa28dbbf1b8867c5320f4be8330d1 352 SUPERFAMILY SSF53335 102 348 7.09E-53 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS20915 7c782a63ea1a46c674f570fae7ff5d2f 595 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS20915 7c782a63ea1a46c674f570fae7ff5d2f 595 Pfam PF00069 Protein kinase domain 10 271 4.5E-51 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS20915 7c782a63ea1a46c674f570fae7ff5d2f 595 Gene3D G3DSA:3.30.200.20 5 116 2.9E-21 T 06-07-2017 SMD11_RS20915 7c782a63ea1a46c674f570fae7ff5d2f 595 Gene3D G3DSA:1.10.510.10 117 272 1.8E-54 T 06-07-2017 SMD11_RS20915 7c782a63ea1a46c674f570fae7ff5d2f 595 Gene3D G3DSA:1.10.510.10 396 472 1.8E-54 T 06-07-2017 SMD11_RS20915 7c782a63ea1a46c674f570fae7ff5d2f 595 SMART SM00220 8 277 5.3E-73 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS20915 7c782a63ea1a46c674f570fae7ff5d2f 595 SUPERFAMILY SSF56112 5 277 2.29E-78 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS20915 7c782a63ea1a46c674f570fae7ff5d2f 595 SUPERFAMILY SSF56112 429 478 2.29E-78 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS09530 21a3a775733436123aaf9a1d887bc972 185 SUPERFAMILY SSF46689 3 75 3.89E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS09530 21a3a775733436123aaf9a1d887bc972 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 4.4E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS09530 21a3a775733436123aaf9a1d887bc972 185 Gene3D G3DSA:1.10.357.10 3 185 1.6E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS09530 21a3a775733436123aaf9a1d887bc972 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.7E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS09530 21a3a775733436123aaf9a1d887bc972 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.7E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS10595 bfe5ac3668d479cf6223431afabb900e 215 Gene3D G3DSA:1.10.357.10 69 211 3.2E-37 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS10595 bfe5ac3668d479cf6223431afabb900e 215 Gene3D G3DSA:1.10.10.60 20 66 4.6E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS10595 bfe5ac3668d479cf6223431afabb900e 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 2.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS10595 bfe5ac3668d479cf6223431afabb900e 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 2.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS10595 bfe5ac3668d479cf6223431afabb900e 215 SUPERFAMILY SSF48498 91 211 1.78E-15 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS10595 bfe5ac3668d479cf6223431afabb900e 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 74 4.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS10595 bfe5ac3668d479cf6223431afabb900e 215 Pfam PF16859 Bacterial transcriptional repressor C-terminal 87 205 3.2E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS10595 bfe5ac3668d479cf6223431afabb900e 215 SUPERFAMILY SSF46689 20 86 1.05E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS23040 10db2ffb83b17a62cec67f50ccb9cbe8 474 PIRSF PIRSF000538 1 469 3.2E-66 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD11_RS23040 10db2ffb83b17a62cec67f50ccb9cbe8 474 Gene3D G3DSA:3.30.420.40 236 463 2.7E-23 T 06-07-2017 SMD11_RS23040 10db2ffb83b17a62cec67f50ccb9cbe8 474 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 229 4.2E-36 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMD11_RS23040 10db2ffb83b17a62cec67f50ccb9cbe8 474 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 122 134 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD11_RS23040 10db2ffb83b17a62cec67f50ccb9cbe8 474 SUPERFAMILY SSF53067 236 451 1.4E-33 T 06-07-2017 SMD11_RS23040 10db2ffb83b17a62cec67f50ccb9cbe8 474 Gene3D G3DSA:3.30.420.40 3 230 4.9E-39 T 06-07-2017 SMD11_RS23040 10db2ffb83b17a62cec67f50ccb9cbe8 474 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 333 354 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD11_RS23040 10db2ffb83b17a62cec67f50ccb9cbe8 474 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 238 421 1.7E-18 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMD11_RS23040 10db2ffb83b17a62cec67f50ccb9cbe8 474 SUPERFAMILY SSF53067 4 233 5.83E-40 T 06-07-2017 SMD11_RS22905 46944356ddc936ca8a174921e0b74aee 193 SUPERFAMILY SSF46689 6 77 6.48E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS22905 46944356ddc936ca8a174921e0b74aee 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 53 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD11_RS22905 46944356ddc936ca8a174921e0b74aee 193 Gene3D G3DSA:1.10.357.10 7 193 8.9E-36 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS22905 46944356ddc936ca8a174921e0b74aee 193 SUPERFAMILY SSF48498 84 192 7.53E-11 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS22905 46944356ddc936ca8a174921e0b74aee 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 6.7E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS22905 46944356ddc936ca8a174921e0b74aee 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.8E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS22905 46944356ddc936ca8a174921e0b74aee 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.8E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS15805 35f3322d3db8eddb11fd7c1ab65cacf2 218 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 99 189 9.0E-14 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMD11_RS04035 4cb67a042504c16647a0f3745cad8456 264 Pfam PF13649 Methyltransferase domain 42 134 1.5E-18 T 06-07-2017 SMD11_RS04035 4cb67a042504c16647a0f3745cad8456 264 SUPERFAMILY SSF53335 13 238 3.73E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS04035 4cb67a042504c16647a0f3745cad8456 264 Gene3D G3DSA:3.40.50.150 14 143 9.0E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS04035 4cb67a042504c16647a0f3745cad8456 264 Gene3D G3DSA:3.40.50.150 183 227 9.0E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS17360 7dcd0ab2eb9a5e74f5bf71c51be15984 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 217 6.7E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS17360 7dcd0ab2eb9a5e74f5bf71c51be15984 217 SUPERFAMILY SSF52172 1 169 2.7E-36 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS17360 7dcd0ab2eb9a5e74f5bf71c51be15984 217 Pfam PF00072 Response regulator receiver domain 3 112 5.6E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS17360 7dcd0ab2eb9a5e74f5bf71c51be15984 217 SMART SM00862 145 217 2.8E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS17360 7dcd0ab2eb9a5e74f5bf71c51be15984 217 Gene3D G3DSA:1.10.10.10 123 217 7.6E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17360 7dcd0ab2eb9a5e74f5bf71c51be15984 217 SMART SM00448 1 112 3.3E-36 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS17360 7dcd0ab2eb9a5e74f5bf71c51be15984 217 Gene3D G3DSA:3.40.50.2300 1 120 3.6E-33 T 06-07-2017 SMD11_RS00905 dfa8d8bd4d791a6abf2e1b7e6d5c00aa 165 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 64 3.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00905 dfa8d8bd4d791a6abf2e1b7e6d5c00aa 165 Gene3D G3DSA:1.10.357.10 22 150 5.1E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS00905 dfa8d8bd4d791a6abf2e1b7e6d5c00aa 165 SUPERFAMILY SSF46689 22 80 7.56E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 Pfam PF00400 WD domain, G-beta repeat 675 712 2.6E-8 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 Pfam PF00400 WD domain, G-beta repeat 767 796 1.5E-5 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 Pfam PF00400 WD domain, G-beta repeat 974 1011 7.6E-9 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 Pfam PF00400 WD domain, G-beta repeat 805 838 6.4E-8 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 Pfam PF00400 WD domain, G-beta repeat 718 754 4.9E-11 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 Pfam PF00400 WD domain, G-beta repeat 845 880 2.9E-6 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 Pfam PF00400 WD domain, G-beta repeat 638 670 5.2E-7 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 SUPERFAMILY SSF50998 896 1026 6.04E-29 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 Gene3D G3DSA:3.40.50.300 81 231 1.2E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 867 881 - T 06-07-2017 IPR019775 WD40 repeat, conserved site SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 699 713 - T 06-07-2017 IPR019775 WD40 repeat, conserved site SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 SMART SM00320 757 796 3.1E-7 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 SMART SM00320 631 670 9.8E-9 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 SMART SM00320 673 712 9.3E-13 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 SMART SM00320 799 838 1.0E-11 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 SMART SM00320 930 969 0.0021 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 SMART SM00320 883 927 0.78 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 SMART SM00320 715 754 1.0E-12 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 SMART SM00320 841 880 2.2E-9 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 SMART SM00320 972 1011 4.1E-12 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 825 839 - T 06-07-2017 IPR019775 WD40 repeat, conserved site SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 657 671 - T 06-07-2017 IPR019775 WD40 repeat, conserved site SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 Gene3D G3DSA:2.130.10.10 636 771 2.3E-50 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 SUPERFAMILY SSF52540 79 172 1.35E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 SUPERFAMILY SSF52540 219 315 1.35E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 SUPERFAMILY SSF50978 637 914 1.65E-92 T 06-07-2017 IPR017986 WD40-repeat-containing domain GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 Gene3D G3DSA:2.130.10.10 906 1021 2.5E-29 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 Gene3D G3DSA:2.130.10.10 772 905 2.0E-47 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 783 797 - T 06-07-2017 IPR019775 WD40 repeat, conserved site SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 PRINTS PR00320 G protein beta WD-40 repeat signature 825 839 8.4E-7 T 06-07-2017 IPR020472 G-protein beta WD-40 repeat SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 PRINTS PR00320 G protein beta WD-40 repeat signature 741 755 8.4E-7 T 06-07-2017 IPR020472 G-protein beta WD-40 repeat SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 PRINTS PR00320 G protein beta WD-40 repeat signature 699 713 8.4E-7 T 06-07-2017 IPR020472 G-protein beta WD-40 repeat SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 998 1012 - T 06-07-2017 IPR019775 WD40 repeat, conserved site SMD11_RS02000 d05c47489ab4217cfa5d778763de2ac4 1248 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 741 755 - T 06-07-2017 IPR019775 WD40 repeat, conserved site SMD11_RS21095 d9ff4fb2bfeecb4365bb3207da069ad6 301 SUPERFAMILY SSF46785 2 112 2.01E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21095 d9ff4fb2bfeecb4365bb3207da069ad6 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS21095 d9ff4fb2bfeecb4365bb3207da069ad6 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS21095 d9ff4fb2bfeecb4365bb3207da069ad6 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS21095 d9ff4fb2bfeecb4365bb3207da069ad6 301 Pfam PF03466 LysR substrate binding domain 90 295 2.9E-39 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS21095 d9ff4fb2bfeecb4365bb3207da069ad6 301 Gene3D G3DSA:1.10.10.10 3 86 4.6E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21095 d9ff4fb2bfeecb4365bb3207da069ad6 301 Gene3D G3DSA:3.40.190.10 89 185 4.8E-25 T 06-07-2017 SMD11_RS21095 d9ff4fb2bfeecb4365bb3207da069ad6 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 9.4E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS21095 d9ff4fb2bfeecb4365bb3207da069ad6 301 Gene3D G3DSA:3.40.190.10 186 264 9.6E-19 T 06-07-2017 SMD11_RS21095 d9ff4fb2bfeecb4365bb3207da069ad6 301 SUPERFAMILY SSF53850 91 298 9.96E-36 T 06-07-2017 SMD11_RS29045 d54fb0b5d6cb008d880a7a667a2a401d 530 Pfam PF00881 Nitroreductase family 341 517 2.1E-13 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMD11_RS29045 d54fb0b5d6cb008d880a7a667a2a401d 530 SUPERFAMILY SSF55469 430 518 8.27E-11 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS29045 d54fb0b5d6cb008d880a7a667a2a401d 530 SUPERFAMILY SSF55469 334 392 8.27E-11 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS29045 d54fb0b5d6cb008d880a7a667a2a401d 530 Gene3D G3DSA:3.40.109.10 333 518 2.8E-11 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS29045 d54fb0b5d6cb008d880a7a667a2a401d 530 Gene3D G3DSA:3.40.109.10 198 257 2.6E-4 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS29045 d54fb0b5d6cb008d880a7a667a2a401d 530 SUPERFAMILY SSF55469 117 130 1.38E-6 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS29045 d54fb0b5d6cb008d880a7a667a2a401d 530 SUPERFAMILY SSF55469 159 256 1.38E-6 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS05380 0b2be8179fab65d5d51436f8c9a2f358 624 Pfam PF01066 CDP-alcohol phosphatidyltransferase 215 281 1.4E-8 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD11_RS05380 0b2be8179fab65d5d51436f8c9a2f358 624 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 259 281 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD11_RS04580 ab29022b19d6d92cd4a7fcd8c31ec4c9 127 SUPERFAMILY SSF46785 6 81 3.56E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04580 ab29022b19d6d92cd4a7fcd8c31ec4c9 127 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 5.6E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS04580 ab29022b19d6d92cd4a7fcd8c31ec4c9 127 SMART SM00345 18 77 2.4E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS04580 ab29022b19d6d92cd4a7fcd8c31ec4c9 127 Gene3D G3DSA:1.10.10.10 5 78 3.3E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14080 4267a736bcf947540b9183e0d2655cb2 163 SUPERFAMILY SSF55729 1 163 1.36E-28 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS14080 4267a736bcf947540b9183e0d2655cb2 163 Gene3D G3DSA:3.40.630.30 1 163 3.5E-30 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS14080 4267a736bcf947540b9183e0d2655cb2 163 Pfam PF00583 Acetyltransferase (GNAT) family 58 136 9.1E-11 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS17675 a9994273c3ac60079c6a0054a4de5279 135 SUPERFAMILY SSF50475 10 132 2.46E-28 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS17675 a9994273c3ac60079c6a0054a4de5279 135 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 13 131 1.1E-26 T 06-07-2017 IPR019920 F420-binding domain, putative SMD11_RS17675 a9994273c3ac60079c6a0054a4de5279 135 Gene3D G3DSA:2.30.110.10 9 132 3.7E-34 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS17675 a9994273c3ac60079c6a0054a4de5279 135 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 96 7.1E-13 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD11_RS14565 47b6adc7fd49b5fb4508b053427638fd 259 Gene3D G3DSA:3.40.50.300 3 251 5.3E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14565 47b6adc7fd49b5fb4508b053427638fd 259 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 259 5.9E-112 T 06-07-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 SMD11_RS14565 47b6adc7fd49b5fb4508b053427638fd 259 Pfam PF00005 ABC transporter 21 177 1.9E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS14565 47b6adc7fd49b5fb4508b053427638fd 259 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS14565 47b6adc7fd49b5fb4508b053427638fd 259 SUPERFAMILY SSF52540 5 247 6.93E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14565 47b6adc7fd49b5fb4508b053427638fd 259 SMART SM00382 29 230 9.3E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS17705 72c5b460c4486c6e9de0a98f377daf7e 530 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 197 519 20.991 T 06-07-2017 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 SMD11_RS17705 72c5b460c4486c6e9de0a98f377daf7e 530 Pfam PF01564 Spermine/spermidine synthase 257 443 5.2E-31 T 06-07-2017 SMD11_RS17705 72c5b460c4486c6e9de0a98f377daf7e 530 Gene3D G3DSA:3.40.50.150 283 483 2.5E-56 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS17705 72c5b460c4486c6e9de0a98f377daf7e 530 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 303 316 - T 06-07-2017 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 SMD11_RS17705 72c5b460c4486c6e9de0a98f377daf7e 530 SUPERFAMILY SSF53335 238 450 2.46E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS17705 72c5b460c4486c6e9de0a98f377daf7e 530 SUPERFAMILY SSF103473 16 201 9.68E-7 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS33470 b37f249b728f977909d0b86c8b8dbf67 570 SUPERFAMILY SSF51905 4 183 7.07E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS33470 b37f249b728f977909d0b86c8b8dbf67 570 SUPERFAMILY SSF51905 284 390 7.07E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS33470 b37f249b728f977909d0b86c8b8dbf67 570 Gene3D G3DSA:3.50.50.60 5 180 1.9E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS33470 b37f249b728f977909d0b86c8b8dbf67 570 Gene3D G3DSA:3.50.50.60 285 324 1.9E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS33470 b37f249b728f977909d0b86c8b8dbf67 570 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 1.7E-11 T 06-07-2017 SMD11_RS33470 b37f249b728f977909d0b86c8b8dbf67 570 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 1.7E-11 T 06-07-2017 SMD11_RS33470 b37f249b728f977909d0b86c8b8dbf67 570 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.7E-11 T 06-07-2017 SMD11_RS33470 b37f249b728f977909d0b86c8b8dbf67 570 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 1.7E-11 T 06-07-2017 SMD11_RS33470 b37f249b728f977909d0b86c8b8dbf67 570 Pfam PF04820 Tryptophan halogenase 99 386 1.1E-28 T 06-07-2017 IPR006905 Tryptophan halogenase SMD11_RS33470 b37f249b728f977909d0b86c8b8dbf67 570 Pfam PF04820 Tryptophan halogenase 6 91 3.0E-12 T 06-07-2017 IPR006905 Tryptophan halogenase SMD11_RS30810 f33139508c65229666977ac8950c64ba 190 SUPERFAMILY SSF46689 11 71 2.09E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS30810 f33139508c65229666977ac8950c64ba 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 64 1.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS30810 f33139508c65229666977ac8950c64ba 190 SUPERFAMILY SSF48498 79 186 5.11E-16 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS30810 f33139508c65229666977ac8950c64ba 190 Pfam PF16859 Bacterial transcriptional repressor C-terminal 77 181 1.5E-16 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS30810 f33139508c65229666977ac8950c64ba 190 Gene3D G3DSA:1.10.357.10 60 188 1.1E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS30810 f33139508c65229666977ac8950c64ba 190 Gene3D G3DSA:1.10.10.60 10 58 8.7E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS09615 d1e1aef48fecc78a018c2855c0b60fee 471 Gene3D G3DSA:3.40.50.800 284 399 6.6E-31 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS09615 d1e1aef48fecc78a018c2855c0b60fee 471 SUPERFAMILY SSF52954 279 399 2.62E-26 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS09615 d1e1aef48fecc78a018c2855c0b60fee 471 Hamap MF_01571 Proline--tRNA ligase [proS]. 7 471 39.961 T 06-07-2017 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 SMD11_RS09615 d1e1aef48fecc78a018c2855c0b60fee 471 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 102 268 2.1E-13 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS09615 d1e1aef48fecc78a018c2855c0b60fee 471 SMART SM00946 409 471 1.4E-4 T 06-07-2017 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 SMD11_RS09615 d1e1aef48fecc78a018c2855c0b60fee 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 3.7E-6 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD11_RS09615 d1e1aef48fecc78a018c2855c0b60fee 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 65 83 3.7E-6 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD11_RS09615 d1e1aef48fecc78a018c2855c0b60fee 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 145 156 3.7E-6 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD11_RS09615 d1e1aef48fecc78a018c2855c0b60fee 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 3.7E-6 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SMD11_RS09615 d1e1aef48fecc78a018c2855c0b60fee 471 SUPERFAMILY SSF55681 12 277 4.97E-74 T 06-07-2017 SMD11_RS09615 d1e1aef48fecc78a018c2855c0b60fee 471 Gene3D G3DSA:3.30.930.10 5 283 4.4E-105 T 06-07-2017 SMD11_RS09615 d1e1aef48fecc78a018c2855c0b60fee 471 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 9 416 1.2E-145 T 06-07-2017 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 SMD11_RS09615 d1e1aef48fecc78a018c2855c0b60fee 471 Pfam PF03129 Anticodon binding domain 290 380 5.7E-14 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS13545 fb03385f5ef0b0f97ab30276fee4e64e 290 Pfam PF13740 ACT domain 13 69 2.4E-5 T 06-07-2017 SMD11_RS13545 fb03385f5ef0b0f97ab30276fee4e64e 290 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 13 289 2.4E-103 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD11_RS13545 fb03385f5ef0b0f97ab30276fee4e64e 290 Pfam PF00551 Formyl transferase 94 271 6.1E-37 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS13545 fb03385f5ef0b0f97ab30276fee4e64e 290 Gene3D G3DSA:3.30.70.260 8 90 4.4E-31 T 06-07-2017 SMD11_RS13545 fb03385f5ef0b0f97ab30276fee4e64e 290 SUPERFAMILY SSF55021 10 91 3.91E-20 T 06-07-2017 SMD11_RS13545 fb03385f5ef0b0f97ab30276fee4e64e 290 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 9 289 48.362 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD11_RS13545 fb03385f5ef0b0f97ab30276fee4e64e 290 SUPERFAMILY SSF53328 94 289 5.1E-63 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS13545 fb03385f5ef0b0f97ab30276fee4e64e 290 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 241 263 2.6E-52 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD11_RS13545 fb03385f5ef0b0f97ab30276fee4e64e 290 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 46 58 2.6E-52 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD11_RS13545 fb03385f5ef0b0f97ab30276fee4e64e 290 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 117 144 2.6E-52 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD11_RS13545 fb03385f5ef0b0f97ab30276fee4e64e 290 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 263 288 2.6E-52 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD11_RS13545 fb03385f5ef0b0f97ab30276fee4e64e 290 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 95 117 2.6E-52 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD11_RS13545 fb03385f5ef0b0f97ab30276fee4e64e 290 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 14 40 2.6E-52 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD11_RS13545 fb03385f5ef0b0f97ab30276fee4e64e 290 Gene3D G3DSA:3.40.50.170 94 289 1.0E-55 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SMD11_RS13545 fb03385f5ef0b0f97ab30276fee4e64e 290 PIRSF PIRSF036480 9 290 2.5E-115 T 06-07-2017 SMD11_RS03375 013ec25962340ed072e9f98fa69a7125 195 Gene3D G3DSA:1.10.357.10 10 187 3.7E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS03375 013ec25962340ed072e9f98fa69a7125 195 SUPERFAMILY SSF46689 11 77 8.03E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS03375 013ec25962340ed072e9f98fa69a7125 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS03375 013ec25962340ed072e9f98fa69a7125 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS03375 013ec25962340ed072e9f98fa69a7125 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 2.3E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS10380 94a70bb64751e8ad51aa217734c4f3b5 304 Gene3D G3DSA:1.10.260.40 2 82 1.7E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS10380 94a70bb64751e8ad51aa217734c4f3b5 304 SMART SM00530 10 83 9.2E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS10380 94a70bb64751e8ad51aa217734c4f3b5 304 SUPERFAMILY SSF47413 7 82 1.84E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS10380 94a70bb64751e8ad51aa217734c4f3b5 304 Pfam PF13560 Helix-turn-helix domain 6 86 3.0E-20 T 06-07-2017 SMD11_RS08230 53dedfd7ee6f740beb9d3c6b12e261c5 509 Gene3D G3DSA:3.40.50.980 156 313 7.2E-28 T 06-07-2017 SMD11_RS08230 53dedfd7ee6f740beb9d3c6b12e261c5 509 Gene3D G3DSA:3.40.50.980 1 155 4.9E-33 T 06-07-2017 SMD11_RS08230 53dedfd7ee6f740beb9d3c6b12e261c5 509 Gene3D G3DSA:2.30.38.10 314 390 2.6E-25 T 06-07-2017 SMD11_RS08230 53dedfd7ee6f740beb9d3c6b12e261c5 509 Pfam PF00501 AMP-binding enzyme 7 400 9.4E-88 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS08230 53dedfd7ee6f740beb9d3c6b12e261c5 509 Gene3D G3DSA:3.30.300.30 395 488 2.8E-14 T 06-07-2017 SMD11_RS08230 53dedfd7ee6f740beb9d3c6b12e261c5 509 SUPERFAMILY SSF56801 1 488 8.77E-125 T 06-07-2017 SMD11_RS08230 53dedfd7ee6f740beb9d3c6b12e261c5 509 Pfam PF13193 AMP-binding enzyme C-terminal domain 409 477 3.2E-6 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS15930 7238b345f96dff24333751be4517709b 479 SUPERFAMILY SSF48557 45 477 9.42E-89 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 SMD11_RS15930 7238b345f96dff24333751be4517709b 479 Gene3D G3DSA:1.10.40.30 406 477 1.4E-18 T 06-07-2017 SMD11_RS15930 7238b345f96dff24333751be4517709b 479 Pfam PF00206 Lyase 46 333 5.5E-34 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal SMD11_RS15930 7238b345f96dff24333751be4517709b 479 Pfam PF10397 Adenylosuccinate lyase C-terminus 401 476 1.2E-12 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS15930 7238b345f96dff24333751be4517709b 479 Gene3D G3DSA:1.10.275.10 38 127 7.1E-29 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal SMD11_RS15930 7238b345f96dff24333751be4517709b 479 SMART SM00998 398 477 6.9E-12 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS15930 7238b345f96dff24333751be4517709b 479 Gene3D G3DSA:1.20.200.10 128 405 1.1E-88 T 06-07-2017 SMD11_RS15930 7238b345f96dff24333751be4517709b 479 PRINTS PR00149 Fumarate lyase superfamily signature 125 143 2.4E-17 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS15930 7238b345f96dff24333751be4517709b 479 PRINTS PR00149 Fumarate lyase superfamily signature 310 326 2.4E-17 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS15930 7238b345f96dff24333751be4517709b 479 PRINTS PR00149 Fumarate lyase superfamily signature 265 292 2.4E-17 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS15930 7238b345f96dff24333751be4517709b 479 PRINTS PR00149 Fumarate lyase superfamily signature 170 188 2.4E-17 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS28100 e7a781a7b6425396a5b80d6561e7d263 439 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.0E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS28100 e7a781a7b6425396a5b80d6561e7d263 439 SMART SM00345 15 74 2.7E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS28100 e7a781a7b6425396a5b80d6561e7d263 439 Gene3D G3DSA:1.10.10.10 14 78 1.1E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28100 e7a781a7b6425396a5b80d6561e7d263 439 Gene3D G3DSA:3.90.1150.10 317 411 7.9E-5 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS28100 e7a781a7b6425396a5b80d6561e7d263 439 Gene3D G3DSA:3.40.640.10 127 316 9.0E-29 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS28100 e7a781a7b6425396a5b80d6561e7d263 439 SUPERFAMILY SSF46785 13 78 3.53E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28100 e7a781a7b6425396a5b80d6561e7d263 439 SUPERFAMILY SSF53383 69 413 1.57E-47 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS06960 9cd2d7dba2e66340f146fec707292115 130 Pfam PF13309 HTH domain 56 117 2.3E-21 T 06-07-2017 SMD11_RS32770 c7c0f52cbcfd3454cae5f5c3ba8510c5 573 SUPERFAMILY SSF56645 16 238 4.97E-25 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS32770 c7c0f52cbcfd3454cae5f5c3ba8510c5 573 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 393 1.9E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS32770 c7c0f52cbcfd3454cae5f5c3ba8510c5 573 Gene3D G3DSA:2.40.110.10 136 231 2.7E-11 T 06-07-2017 SMD11_RS32770 c7c0f52cbcfd3454cae5f5c3ba8510c5 573 SUPERFAMILY SSF47203 244 399 4.03E-26 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS32770 c7c0f52cbcfd3454cae5f5c3ba8510c5 573 Gene3D G3DSA:1.20.140.10 232 394 2.9E-22 T 06-07-2017 SMD11_RS01880 4909b2b613d7dc60d10563369faa62f4 425 PRINTS PR01182 Ornithine decarboxylase signature 92 116 1.6E-5 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 SMD11_RS01880 4909b2b613d7dc60d10563369faa62f4 425 PRINTS PR01182 Ornithine decarboxylase signature 48 75 1.6E-5 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 SMD11_RS01880 4909b2b613d7dc60d10563369faa62f4 425 PRINTS PR01182 Ornithine decarboxylase signature 341 351 1.6E-5 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 SMD11_RS01880 4909b2b613d7dc60d10563369faa62f4 425 Gene3D G3DSA:3.20.20.10 29 267 1.3E-60 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS01880 4909b2b613d7dc60d10563369faa62f4 425 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 70 82 1.5E-7 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS01880 4909b2b613d7dc60d10563369faa62f4 425 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 183 196 1.5E-7 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS01880 4909b2b613d7dc60d10563369faa62f4 425 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 270 289 1.5E-7 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS01880 4909b2b613d7dc60d10563369faa62f4 425 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 50 68 1.5E-7 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS01880 4909b2b613d7dc60d10563369faa62f4 425 Gene3D G3DSA:2.40.37.10 268 419 2.0E-37 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS01880 4909b2b613d7dc60d10563369faa62f4 425 SUPERFAMILY SSF50621 262 417 7.53E-38 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS01880 4909b2b613d7dc60d10563369faa62f4 425 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 35 280 4.4E-39 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMD11_RS01880 4909b2b613d7dc60d10563369faa62f4 425 SUPERFAMILY SSF51419 20 282 2.45E-58 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS01880 4909b2b613d7dc60d10563369faa62f4 425 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 297 395 1.2E-13 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMD11_RS17115 d8888e00c02287ce411daf83bd987ff8 169 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 23 168 2.9E-53 T 06-07-2017 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit SMD11_RS17115 d8888e00c02287ce411daf83bd987ff8 169 Pfam PF01883 Domain of unknown function DUF59 21 88 3.1E-14 T 06-07-2017 IPR002744 Domain of unknown function DUF59 SMD11_RS17115 d8888e00c02287ce411daf83bd987ff8 169 SUPERFAMILY SSF117916 11 106 2.78E-20 T 06-07-2017 SMD11_RS09470 d836a9a90527a18f525da0bdfbf054b9 370 SUPERFAMILY SSF102405 145 201 1.37E-27 T 06-07-2017 SMD11_RS09470 d836a9a90527a18f525da0bdfbf054b9 370 SUPERFAMILY SSF102405 242 361 1.37E-27 T 06-07-2017 SMD11_RS09470 d836a9a90527a18f525da0bdfbf054b9 370 Pfam PF03641 Possible lysine decarboxylase 240 329 5.3E-5 T 06-07-2017 IPR031100 LOG family SMD11_RS09470 d836a9a90527a18f525da0bdfbf054b9 370 Gene3D G3DSA:3.40.50.450 147 205 5.8E-40 T 06-07-2017 SMD11_RS09470 d836a9a90527a18f525da0bdfbf054b9 370 Gene3D G3DSA:3.40.50.450 239 329 5.8E-40 T 06-07-2017 SMD11_RS02975 041521ac136f4effdb15eb852ff80873 223 Gene3D G3DSA:1.20.120.530 87 212 4.2E-23 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS02975 041521ac136f4effdb15eb852ff80873 223 SMART SM00345 25 83 4.4E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS02975 041521ac136f4effdb15eb852ff80873 223 Pfam PF07729 FCD domain 93 204 5.1E-18 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS02975 041521ac136f4effdb15eb852ff80873 223 SUPERFAMILY SSF46785 17 110 5.98E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02975 041521ac136f4effdb15eb852ff80873 223 SMART SM00895 93 214 2.3E-14 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS02975 041521ac136f4effdb15eb852ff80873 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 83 4.2E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS02975 041521ac136f4effdb15eb852ff80873 223 Gene3D G3DSA:1.10.10.10 11 83 9.9E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02975 041521ac136f4effdb15eb852ff80873 223 SUPERFAMILY SSF48008 90 215 9.68E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS17720 b78d8c9fd83b7908c4336a665fba27a6 216 SUPERFAMILY SSF51735 1 214 1.01E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17720 b78d8c9fd83b7908c4336a665fba27a6 216 Pfam PF13460 NAD(P)H-binding 8 201 1.8E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17720 b78d8c9fd83b7908c4336a665fba27a6 216 Gene3D G3DSA:3.40.50.720 1 216 2.9E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS27265 da3f171107b70c53f46e20c16d0821d0 142 Pfam PF06103 Bacterial protein of unknown function (DUF948) 1 81 4.6E-11 T 06-07-2017 IPR009293 Uncharacterised protein family UPF0478 SMD11_RS13840 3643af04e8f53665d2c9f1c9988023bf 282 SMART SM00382 33 222 1.2E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS13840 3643af04e8f53665d2c9f1c9988023bf 282 Pfam PF00005 ABC transporter 25 172 4.7E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS13840 3643af04e8f53665d2c9f1c9988023bf 282 Gene3D G3DSA:3.40.50.300 5 243 3.5E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13840 3643af04e8f53665d2c9f1c9988023bf 282 SUPERFAMILY SSF52540 7 234 1.38E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13840 3643af04e8f53665d2c9f1c9988023bf 282 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS28275 edd023ed53ab50082b54cb9d91486af3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28275 edd023ed53ab50082b54cb9d91486af3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 3.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28275 edd023ed53ab50082b54cb9d91486af3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28275 edd023ed53ab50082b54cb9d91486af3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 3.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28275 edd023ed53ab50082b54cb9d91486af3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 3.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28275 edd023ed53ab50082b54cb9d91486af3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28275 edd023ed53ab50082b54cb9d91486af3 253 SUPERFAMILY SSF51735 6 250 3.38E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS28275 edd023ed53ab50082b54cb9d91486af3 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 3.4E-61 T 06-07-2017 SMD11_RS28275 edd023ed53ab50082b54cb9d91486af3 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS28275 edd023ed53ab50082b54cb9d91486af3 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28275 edd023ed53ab50082b54cb9d91486af3 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28275 edd023ed53ab50082b54cb9d91486af3 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS28275 edd023ed53ab50082b54cb9d91486af3 253 Gene3D G3DSA:3.40.50.720 4 250 2.7E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS28275 edd023ed53ab50082b54cb9d91486af3 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 4.8E-6 T 06-07-2017 SMD11_RS08960 b40a24aecfeb0e458040b16fba8dc397 64 Pfam PF11248 Protein of unknown function (DUF3046) 1 61 1.4E-30 T 06-07-2017 IPR021408 Protein of unknown function DUF3046 SMD11_RS14700 65b4effa3c8536877d104a1aaf750c4e 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 2.1E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS14700 65b4effa3c8536877d104a1aaf750c4e 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 2.1E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS14700 65b4effa3c8536877d104a1aaf750c4e 216 SUPERFAMILY SSF48498 97 206 1.93E-31 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS14700 65b4effa3c8536877d104a1aaf750c4e 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 76 3.4E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS14700 65b4effa3c8536877d104a1aaf750c4e 216 Gene3D G3DSA:1.10.357.10 91 206 5.7E-42 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS14700 65b4effa3c8536877d104a1aaf750c4e 216 Gene3D G3DSA:1.10.10.60 26 77 1.1E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS14700 65b4effa3c8536877d104a1aaf750c4e 216 SUPERFAMILY SSF46689 21 89 8.72E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS32420 7d18da1dd41e29f827ae93d692ecd769 232 Gene3D G3DSA:3.40.50.2300 9 128 3.9E-40 T 06-07-2017 SMD11_RS32420 7d18da1dd41e29f827ae93d692ecd769 232 Pfam PF00072 Response regulator receiver domain 11 121 5.1E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS32420 7d18da1dd41e29f827ae93d692ecd769 232 SMART SM00862 154 229 1.4E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS32420 7d18da1dd41e29f827ae93d692ecd769 232 Gene3D G3DSA:1.10.10.10 130 231 4.2E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32420 7d18da1dd41e29f827ae93d692ecd769 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 228 1.9E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS32420 7d18da1dd41e29f827ae93d692ecd769 232 SMART SM00448 9 120 2.3E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS32420 7d18da1dd41e29f827ae93d692ecd769 232 SUPERFAMILY SSF52172 7 185 5.57E-43 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS11610 765ca399524e8a94c6784770fa5b15be 131 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 24 84 4.0E-18 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS11610 765ca399524e8a94c6784770fa5b15be 131 Gene3D G3DSA:1.10.10.10 23 81 1.3E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11610 765ca399524e8a94c6784770fa5b15be 131 SUPERFAMILY SSF46767 23 83 2.09E-14 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 SMART SM00382 91 245 1.8E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 Gene3D G3DSA:3.40.50.300 68 276 5.9E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 Pfam PF13481 AAA domain 81 223 7.9E-14 T 06-07-2017 SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 Hamap MF_01498 DNA repair protein RadA [radA]. 28 455 42.337 T 06-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 PRINTS PR01874 DNA repair protein radA signature 249 275 9.9E-86 T 06-07-2017 SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 PRINTS PR01874 DNA repair protein radA signature 125 142 9.9E-86 T 06-07-2017 SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 PRINTS PR01874 DNA repair protein radA signature 17 41 9.9E-86 T 06-07-2017 SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 PRINTS PR01874 DNA repair protein radA signature 214 242 9.9E-86 T 06-07-2017 SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 PRINTS PR01874 DNA repair protein radA signature 175 199 9.9E-86 T 06-07-2017 SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 PRINTS PR01874 DNA repair protein radA signature 323 346 9.9E-86 T 06-07-2017 SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 PRINTS PR01874 DNA repair protein radA signature 83 111 9.9E-86 T 06-07-2017 SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 SUPERFAMILY SSF54211 294 454 6.07E-34 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 SUPERFAMILY SSF52540 72 294 2.39E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 TIGRFAM TIGR00416 sms: DNA repair protein RadA 9 451 1.4E-154 T 06-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 Gene3D G3DSA:3.30.230.10 285 454 4.0E-31 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS14725 7673e28392c5fa8c6b42b906c523f0b9 477 Pfam PF13541 Subunit ChlI of Mg-chelatase 371 429 4.5E-8 T 06-07-2017 SMD11_RS09395 20c0f2c8b3435fb50a26b5ffda79ace1 339 SUPERFAMILY SSF103481 199 305 3.66E-15 T 06-07-2017 SMD11_RS09395 20c0f2c8b3435fb50a26b5ffda79ace1 339 SUPERFAMILY SSF103481 58 154 4.45E-13 T 06-07-2017 SMD11_RS09395 20c0f2c8b3435fb50a26b5ffda79ace1 339 Pfam PF00892 EamA-like transporter family 27 153 7.9E-23 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS09395 20c0f2c8b3435fb50a26b5ffda79ace1 339 Pfam PF00892 EamA-like transporter family 166 304 1.6E-22 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS27210 2f1ae5f956d411fbf11169ef549b9771 188 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 18 175 4.1E-61 T 06-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 SMD11_RS27210 2f1ae5f956d411fbf11169ef549b9771 188 Pfam PF00156 Phosphoribosyl transferase domain 45 163 7.4E-14 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMD11_RS27210 2f1ae5f956d411fbf11169ef549b9771 188 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 17 188 35.897 T 06-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 SMD11_RS27210 2f1ae5f956d411fbf11169ef549b9771 188 SUPERFAMILY SSF53271 18 176 1.7E-47 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS27210 2f1ae5f956d411fbf11169ef549b9771 188 Gene3D G3DSA:3.40.50.2020 16 187 2.5E-62 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS08905 fc5e2095f31f8ae4218c861fe5e5a2fd 236 SMART SM00862 159 231 7.4E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS08905 fc5e2095f31f8ae4218c861fe5e5a2fd 236 Gene3D G3DSA:1.10.10.10 137 233 8.0E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08905 fc5e2095f31f8ae4218c861fe5e5a2fd 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 231 2.6E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS08905 fc5e2095f31f8ae4218c861fe5e5a2fd 236 Pfam PF00072 Response regulator receiver domain 4 114 8.0E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS08905 fc5e2095f31f8ae4218c861fe5e5a2fd 236 SUPERFAMILY SSF52172 1 193 1.57E-36 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS08905 fc5e2095f31f8ae4218c861fe5e5a2fd 236 Gene3D G3DSA:3.40.50.2300 1 121 1.1E-35 T 06-07-2017 SMD11_RS08905 fc5e2095f31f8ae4218c861fe5e5a2fd 236 SMART SM00448 1 114 2.6E-36 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS14140 7524471892a33839e10923766c7e4b2f 135 SUPERFAMILY SSF50475 6 133 1.7E-27 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS14140 7524471892a33839e10923766c7e4b2f 135 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 91 2.4E-13 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD11_RS14140 7524471892a33839e10923766c7e4b2f 135 Gene3D G3DSA:2.30.110.10 5 93 1.4E-28 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS14140 7524471892a33839e10923766c7e4b2f 135 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 133 1.6E-40 T 06-07-2017 IPR019920 F420-binding domain, putative SMD11_RS19935 0393eefd0b7f25bbce897d24243cde9b 278 SMART SM00530 18 73 1.3E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS19935 0393eefd0b7f25bbce897d24243cde9b 278 Pfam PF13560 Helix-turn-helix domain 14 75 5.4E-14 T 06-07-2017 SMD11_RS19935 0393eefd0b7f25bbce897d24243cde9b 278 Gene3D G3DSA:1.10.260.40 7 75 2.5E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS19935 0393eefd0b7f25bbce897d24243cde9b 278 SUPERFAMILY SSF47413 11 73 8.31E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS33855 75f035cbad3bcd152511e5295ca3dee7 515 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 356 376 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD11_RS33855 75f035cbad3bcd152511e5295ca3dee7 515 SUPERFAMILY SSF53067 3 250 5.51E-52 T 06-07-2017 SMD11_RS33855 75f035cbad3bcd152511e5295ca3dee7 515 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 245 5.8E-49 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMD11_RS33855 75f035cbad3bcd152511e5295ca3dee7 515 PIRSF PIRSF000538 1 492 9.0E-97 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD11_RS33855 75f035cbad3bcd152511e5295ca3dee7 515 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 326 438 1.4E-25 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMD11_RS33855 75f035cbad3bcd152511e5295ca3dee7 515 SUPERFAMILY SSF53067 251 480 4.66E-48 T 06-07-2017 SMD11_RS33855 75f035cbad3bcd152511e5295ca3dee7 515 Gene3D G3DSA:3.30.420.40 3 247 9.6E-46 T 06-07-2017 SMD11_RS33855 75f035cbad3bcd152511e5295ca3dee7 515 Gene3D G3DSA:3.30.420.40 249 485 4.1E-43 T 06-07-2017 SMD11_RS14695 67b3dcba1431d7f26edb9e41795a4ee1 617 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 611 8.5E-237 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMD11_RS14695 67b3dcba1431d7f26edb9e41795a4ee1 617 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMD11_RS14695 67b3dcba1431d7f26edb9e41795a4ee1 617 SUPERFAMILY SSF143975 4 425 5.89E-131 T 06-07-2017 SMD11_RS14695 67b3dcba1431d7f26edb9e41795a4ee1 617 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 514 525 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMD11_RS14695 67b3dcba1431d7f26edb9e41795a4ee1 617 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 611 44.656 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMD11_RS14695 67b3dcba1431d7f26edb9e41795a4ee1 617 Pfam PF00920 Dehydratase family 34 608 6.8E-215 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 SMD11_RS14695 67b3dcba1431d7f26edb9e41795a4ee1 617 SUPERFAMILY SSF52016 426 612 1.02E-61 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 SUPERFAMILY SSF88659 183 256 4.91E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 SUPERFAMILY SSF88659 241 335 6.94E-23 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 Pfam PF04539 Sigma-70 region 3 189 265 5.3E-24 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 106 332 8.6E-34 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 Pfam PF04542 Sigma-70 region 2 110 180 8.9E-21 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 Pfam PF04545 Sigma-70, region 4 279 331 1.8E-13 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 Gene3D G3DSA:1.10.10.10 273 334 6.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 Pfam PF00140 Sigma-70 factor, region 1.2 33 66 4.9E-11 T 06-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 PRINTS PR00046 Major sigma-70 factor signature 158 166 2.6E-24 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 PRINTS PR00046 Major sigma-70 factor signature 318 329 2.6E-24 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 PRINTS PR00046 Major sigma-70 factor signature 282 294 2.6E-24 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 PRINTS PR00046 Major sigma-70 factor signature 303 318 2.6E-24 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 PRINTS PR00046 Major sigma-70 factor signature 134 147 2.6E-24 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 Gene3D G3DSA:1.10.601.10 102 179 2.7E-55 T 06-07-2017 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 Gene3D G3DSA:1.10.601.10 19 65 2.7E-55 T 06-07-2017 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 SUPERFAMILY SSF88946 33 180 2.35E-46 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 Gene3D G3DSA:1.10.10.10 183 234 1.7E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 134 147 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS19695 54d8dd4fa565fd8435105da8ff8f9974 342 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 303 329 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS29275 380508ece7da5366a65c21d2e5394c31 519 Pfam PF13454 FAD-NAD(P)-binding 29 190 2.1E-25 T 06-07-2017 SMD11_RS29275 380508ece7da5366a65c21d2e5394c31 519 Gene3D G3DSA:3.50.50.60 183 258 1.7E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29275 380508ece7da5366a65c21d2e5394c31 519 SUPERFAMILY SSF51905 26 261 5.05E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29275 380508ece7da5366a65c21d2e5394c31 519 Gene3D G3DSA:3.50.50.60 17 78 1.0E-12 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29275 380508ece7da5366a65c21d2e5394c31 519 Gene3D G3DSA:3.50.50.60 123 182 1.0E-12 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29275 380508ece7da5366a65c21d2e5394c31 519 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 182 200 3.9E-5 T 06-07-2017 SMD11_RS29275 380508ece7da5366a65c21d2e5394c31 519 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 28 47 3.9E-5 T 06-07-2017 SMD11_RS29275 380508ece7da5366a65c21d2e5394c31 519 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 246 3.9E-5 T 06-07-2017 SMD11_RS09175 f5a8ea79e9c0670225d6bf94e1566c8a 419 Pfam PF00082 Subtilase family 56 291 3.1E-40 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS09175 f5a8ea79e9c0670225d6bf94e1566c8a 419 PRINTS PR00723 Subtilisin serine protease family (S8) signature 56 75 1.9E-12 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS09175 f5a8ea79e9c0670225d6bf94e1566c8a 419 PRINTS PR00723 Subtilisin serine protease family (S8) signature 252 268 1.9E-12 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS09175 f5a8ea79e9c0670225d6bf94e1566c8a 419 PRINTS PR00723 Subtilisin serine protease family (S8) signature 95 108 1.9E-12 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related SMD11_RS09175 f5a8ea79e9c0670225d6bf94e1566c8a 419 SUPERFAMILY SSF52743 39 312 1.44E-70 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS09175 f5a8ea79e9c0670225d6bf94e1566c8a 419 Gene3D G3DSA:3.40.50.200 31 312 2.1E-70 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SMD11_RS09175 f5a8ea79e9c0670225d6bf94e1566c8a 419 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 45 394 1.3E-83 T 06-07-2017 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 Gene3D G3DSA:2.60.260.20 116 165 1.9E-21 T 06-07-2017 SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 Gene3D G3DSA:2.60.260.20 234 277 1.9E-21 T 06-07-2017 SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 ProSitePatterns PS00636 Nt-dnaJ domain signature. 52 71 - T 06-07-2017 IPR018253 DnaJ domain, conserved site SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 391 37.609 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 SUPERFAMILY SSF57938 158 233 3.53E-14 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 Pfam PF00684 DnaJ central domain 171 231 4.6E-10 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 374 2.0E-121 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 SUPERFAMILY SSF49493 237 290 1.01E-19 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 SUPERFAMILY SSF49493 138 162 1.01E-19 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 Gene3D G3DSA:2.10.230.10 166 233 3.4E-16 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 Pfam PF00226 DnaJ domain 10 72 3.3E-27 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 SUPERFAMILY SSF46565 9 114 1.2E-31 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 PRINTS PR00625 DnaJ domain signature 30 45 8.0E-23 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 PRINTS PR00625 DnaJ domain signature 12 30 8.0E-23 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 PRINTS PR00625 DnaJ domain signature 67 86 8.0E-23 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 PRINTS PR00625 DnaJ domain signature 47 67 8.0E-23 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 SUPERFAMILY SSF49493 283 368 1.12E-20 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 Gene3D G3DSA:2.60.260.20 280 358 2.3E-20 T 06-07-2017 SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 SMART SM00271 9 67 5.4E-30 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 Gene3D G3DSA:1.10.287.110 4 92 1.2E-31 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS17605 edde8b0de9b7af73fc4595f7e6df74d2 391 Pfam PF01556 DnaJ C terminal domain 144 357 9.5E-35 T 06-07-2017 IPR002939 Chaperone DnaJ, C-terminal SMD11_RS10960 fc64e130b44f58b9021d2cbdf2006a25 171 Gene3D G3DSA:3.30.450.30 80 155 2.4E-8 T 06-07-2017 SMD11_RS10960 fc64e130b44f58b9021d2cbdf2006a25 171 Gene3D G3DSA:3.30.450.30 24 59 2.0E-4 T 06-07-2017 SMD11_RS10960 fc64e130b44f58b9021d2cbdf2006a25 171 SUPERFAMILY SSF103196 23 159 2.59E-20 T 06-07-2017 SMD11_RS10960 fc64e130b44f58b9021d2cbdf2006a25 171 SMART SM00960 29 131 2.8E-14 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS10960 fc64e130b44f58b9021d2cbdf2006a25 171 Pfam PF03259 Roadblock/LC7 domain 80 129 4.0E-6 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS14405 9fddd120cca8d723e153649ac21b4e67 281 SUPERFAMILY SSF52821 151 278 4.71E-34 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS14405 9fddd120cca8d723e153649ac21b4e67 281 ProSitePatterns PS00683 Rhodanese C-terminal signature. 257 267 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 SMD11_RS14405 9fddd120cca8d723e153649ac21b4e67 281 Gene3D G3DSA:3.40.250.10 4 142 4.2E-36 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS14405 9fddd120cca8d723e153649ac21b4e67 281 SMART SM00450 8 124 5.3E-18 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS14405 9fddd120cca8d723e153649ac21b4e67 281 SMART SM00450 146 273 6.3E-21 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS14405 9fddd120cca8d723e153649ac21b4e67 281 SUPERFAMILY SSF52821 4 142 2.88E-34 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS14405 9fddd120cca8d723e153649ac21b4e67 281 Pfam PF00581 Rhodanese-like domain 153 268 1.6E-14 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS14405 9fddd120cca8d723e153649ac21b4e67 281 Pfam PF00581 Rhodanese-like domain 10 120 8.8E-16 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS14405 9fddd120cca8d723e153649ac21b4e67 281 Gene3D G3DSA:3.40.250.10 151 276 3.7E-34 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS27280 661912fa4d06a230c1fc1c5d488c2bf1 154 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 8 137 1.6E-31 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SMD11_RS27280 661912fa4d06a230c1fc1c5d488c2bf1 154 Gene3D G3DSA:3.30.420.140 3 140 1.9E-47 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 SMD11_RS27280 661912fa4d06a230c1fc1c5d488c2bf1 154 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 140 22.578 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SMD11_RS27280 661912fa4d06a230c1fc1c5d488c2bf1 154 Pfam PF03652 Holliday junction resolvase 5 137 2.2E-43 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SMD11_RS27280 661912fa4d06a230c1fc1c5d488c2bf1 154 SUPERFAMILY SSF53098 4 137 6.22E-36 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS27280 661912fa4d06a230c1fc1c5d488c2bf1 154 SMART SM00732 4 105 4.3E-33 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 SMD11_RS13065 c83ea3b90a790075a67ff6eea87aa8d1 156 SUPERFAMILY SSF81343 31 153 4.36E-33 T 06-07-2017 SMD11_RS13065 c83ea3b90a790075a67ff6eea87aa8d1 156 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 40 141 3.2E-16 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS13065 c83ea3b90a790075a67ff6eea87aa8d1 156 Gene3D G3DSA:1.20.950.10 30 155 2.3E-39 T 06-07-2017 SMD11_RS28600 cdd77d5c39c59018207c4cce6436f567 413 Gene3D G3DSA:3.30.470.20 120 296 1.7E-19 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS28600 cdd77d5c39c59018207c4cce6436f567 413 SUPERFAMILY SSF56059 108 325 4.95E-31 T 06-07-2017 SMD11_RS28600 cdd77d5c39c59018207c4cce6436f567 413 Gene3D G3DSA:3.40.50.20 19 119 3.2E-4 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS28600 cdd77d5c39c59018207c4cce6436f567 413 Pfam PF13535 ATP-grasp domain 154 289 8.1E-12 T 06-07-2017 SMD11_RS23960 810a78f0dc0b3230d7a1d2204d33edc8 208 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 90 186 4.3E-14 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD11_RS23960 810a78f0dc0b3230d7a1d2204d33edc8 208 Pfam PF13419 Haloacid dehalogenase-like hydrolase 98 187 3.1E-10 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS23960 810a78f0dc0b3230d7a1d2204d33edc8 208 Gene3D G3DSA:3.40.50.1000 6 204 7.7E-36 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS23960 810a78f0dc0b3230d7a1d2204d33edc8 208 SUPERFAMILY SSF56784 6 193 4.86E-29 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS07440 a9027d9f566d2b707e8b870c8ec3eeb9 531 Pfam PF08386 TAP-like protein 413 512 7.1E-24 T 06-07-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMD11_RS07440 a9027d9f566d2b707e8b870c8ec3eeb9 531 SUPERFAMILY SSF53474 103 157 5.71E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS07440 a9027d9f566d2b707e8b870c8ec3eeb9 531 SUPERFAMILY SSF53474 202 256 5.71E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS07440 a9027d9f566d2b707e8b870c8ec3eeb9 531 SUPERFAMILY SSF53474 401 500 5.71E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS07440 a9027d9f566d2b707e8b870c8ec3eeb9 531 Gene3D G3DSA:3.40.50.1820 379 500 1.8E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS07440 a9027d9f566d2b707e8b870c8ec3eeb9 531 Gene3D G3DSA:3.40.50.1820 200 326 1.8E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS07440 a9027d9f566d2b707e8b870c8ec3eeb9 531 Gene3D G3DSA:3.40.50.1820 70 156 1.8E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS13690 abc44d3e9729da1069db2fb5c4a2e14f 89 Gene3D G3DSA:1.10.10.10 4 75 6.1E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13690 abc44d3e9729da1069db2fb5c4a2e14f 89 SUPERFAMILY SSF46785 2 76 5.04E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13690 abc44d3e9729da1069db2fb5c4a2e14f 89 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 72 4.4E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS13690 abc44d3e9729da1069db2fb5c4a2e14f 89 SMART SM00345 14 72 1.6E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS13690 abc44d3e9729da1069db2fb5c4a2e14f 89 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 2.0E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS13690 abc44d3e9729da1069db2fb5c4a2e14f 89 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 2.0E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS27980 8e4426a7a70e823dc907bc2c28c91fba 467 Gene3D G3DSA:1.10.45.10 426 465 5.6E-13 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 SMD11_RS27980 8e4426a7a70e823dc907bc2c28c91fba 467 Gene3D G3DSA:3.30.43.10 4 100 2.7E-27 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS27980 8e4426a7a70e823dc907bc2c28c91fba 467 Pfam PF01565 FAD binding domain 46 184 2.7E-43 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD11_RS27980 8e4426a7a70e823dc907bc2c28c91fba 467 SUPERFAMILY SSF56176 8 219 3.08E-73 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS27980 8e4426a7a70e823dc907bc2c28c91fba 467 SUPERFAMILY SSF55103 225 466 8.34E-59 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 SMD11_RS27980 8e4426a7a70e823dc907bc2c28c91fba 467 Gene3D G3DSA:3.30.465.10 101 219 2.1E-44 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS27980 8e4426a7a70e823dc907bc2c28c91fba 467 Pfam PF02913 FAD linked oxidases, C-terminal domain 225 465 9.2E-61 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 SMD11_RS08250 51611b71a2f0cbfa44d995af8e15f0ae 344 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 105 116 3.7E-11 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD11_RS08250 51611b71a2f0cbfa44d995af8e15f0ae 344 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 151 165 3.7E-11 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD11_RS08250 51611b71a2f0cbfa44d995af8e15f0ae 344 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 78 86 3.7E-11 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD11_RS08250 51611b71a2f0cbfa44d995af8e15f0ae 344 Pfam PF00561 alpha/beta hydrolase fold 76 329 5.7E-25 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS08250 51611b71a2f0cbfa44d995af8e15f0ae 344 TIGRFAM TIGR01250 pro_imino_pep_2: proline-specific peptidase 53 340 2.1E-81 T 06-07-2017 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD11_RS08250 51611b71a2f0cbfa44d995af8e15f0ae 344 Gene3D G3DSA:3.40.50.1820 54 341 3.1E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS08250 51611b71a2f0cbfa44d995af8e15f0ae 344 PIRSF PIRSF005539 48 344 1.9E-122 T 06-07-2017 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD11_RS08250 51611b71a2f0cbfa44d995af8e15f0ae 344 SUPERFAMILY SSF53474 56 340 1.11E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS13710 df8e52dfe580777f78d1298c8c8bdf86 380 Gene3D G3DSA:3.40.710.10 7 364 9.2E-74 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS13710 df8e52dfe580777f78d1298c8c8bdf86 380 SUPERFAMILY SSF56601 8 364 6.93E-64 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS13710 df8e52dfe580777f78d1298c8c8bdf86 380 Pfam PF00144 Beta-lactamase 22 365 5.3E-59 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS06500 f7f412d0d605ddeb37ca5b9714e91576 321 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 12 242 2.1E-47 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 SMD11_RS06500 f7f412d0d605ddeb37ca5b9714e91576 321 SUPERFAMILY SSF51621 8 253 1.62E-66 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS06500 f7f412d0d605ddeb37ca5b9714e91576 321 PIRSF PIRSF015582 1 320 1.4E-90 T 06-07-2017 IPR011206 Citrate lyase beta subunit-like SMD11_RS06500 f7f412d0d605ddeb37ca5b9714e91576 321 Gene3D G3DSA:3.20.20.60 7 253 5.3E-79 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS23925 81fc5d1acf5f042281a49ae4e83bb964 265 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 157 167 - T 06-07-2017 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 SMD11_RS23925 81fc5d1acf5f042281a49ae4e83bb964 265 Pfam PF13350 Tyrosine phosphatase family 7 264 1.4E-58 T 06-07-2017 IPR026893 Tyrosine/serine-protein phosphatase IphP-type SMD11_RS23925 81fc5d1acf5f042281a49ae4e83bb964 265 SUPERFAMILY SSF52799 6 263 1.33E-46 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like SMD11_RS23925 81fc5d1acf5f042281a49ae4e83bb964 265 Gene3D G3DSA:3.90.190.10 144 206 3.4E-18 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like SMD11_RS23925 81fc5d1acf5f042281a49ae4e83bb964 265 Gene3D G3DSA:3.90.190.10 31 102 3.4E-18 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like SMD11_RS29860 7dce6c8f84767967291c9d8e77947740 210 Pfam PF01323 DSBA-like thioredoxin domain 13 206 3.0E-20 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMD11_RS29860 7dce6c8f84767967291c9d8e77947740 210 SUPERFAMILY SSF52833 8 208 1.15E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS29860 7dce6c8f84767967291c9d8e77947740 210 Gene3D G3DSA:3.40.30.10 9 207 1.3E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS14970 37e1857744db20f78f6cb667f88fa2b3 385 SUPERFAMILY SSF55486 9 379 2.42E-105 T 06-07-2017 SMD11_RS14970 37e1857744db20f78f6cb667f88fa2b3 385 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 10 380 3.4E-141 T 06-07-2017 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated SMD11_RS14970 37e1857744db20f78f6cb667f88fa2b3 385 Pfam PF10103 Zinicin-like metallopeptidase 10 376 1.0E-122 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 SMD11_RS14970 37e1857744db20f78f6cb667f88fa2b3 385 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 10 380 1.5E-124 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 SMD11_RS18560 9ec1c18f0e1d31d8e7ef8873b1262856 464 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 189 204 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18560 9ec1c18f0e1d31d8e7ef8873b1262856 464 Pfam PF10531 SLBB domain 266 311 1.1E-8 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18560 9ec1c18f0e1d31d8e7ef8873b1262856 464 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 31 436 4.2E-188 T 06-07-2017 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18560 9ec1c18f0e1d31d8e7ef8873b1262856 464 SUPERFAMILY SSF142984 264 345 4.84E-21 T 06-07-2017 SMD11_RS18560 9ec1c18f0e1d31d8e7ef8873b1262856 464 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 70 241 2.3E-45 T 06-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18560 9ec1c18f0e1d31d8e7ef8873b1262856 464 SUPERFAMILY SSF142019 29 261 2.75E-85 T 06-07-2017 SMD11_RS18560 9ec1c18f0e1d31d8e7ef8873b1262856 464 SUPERFAMILY SSF140490 346 444 6.41E-38 T 06-07-2017 SMD11_RS18560 9ec1c18f0e1d31d8e7ef8873b1262856 464 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 352 435 7.3E-33 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18560 9ec1c18f0e1d31d8e7ef8873b1262856 464 SMART SM00928 350 395 3.5E-26 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18560 9ec1c18f0e1d31d8e7ef8873b1262856 464 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 363 374 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS16255 eb654ae2220846f92494b7ff2fe0bf26 238 Pfam PF13649 Methyltransferase domain 18 106 1.5E-9 T 06-07-2017 SMD11_RS16255 eb654ae2220846f92494b7ff2fe0bf26 238 SUPERFAMILY SSF53335 3 176 1.28E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS16255 eb654ae2220846f92494b7ff2fe0bf26 238 Gene3D G3DSA:3.40.50.150 2 170 1.7E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS16255 eb654ae2220846f92494b7ff2fe0bf26 238 SMART SM00650 1 147 0.007 T 06-07-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 SMD11_RS21045 d21393ed9e784c1ccb254b79f8eabf2f 554 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 3 147 4.8E-16 T 06-07-2017 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 SMD11_RS21045 d21393ed9e784c1ccb254b79f8eabf2f 554 PIRSF PIRSF001093 67 539 1.2E-77 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21045 d21393ed9e784c1ccb254b79f8eabf2f 554 SUPERFAMILY SSF55545 3 149 1.44E-18 T 06-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21045 d21393ed9e784c1ccb254b79f8eabf2f 554 PRINTS PR00738 Glycosyl hydrolase family 20 signature 244 261 2.6E-37 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21045 d21393ed9e784c1ccb254b79f8eabf2f 554 PRINTS PR00738 Glycosyl hydrolase family 20 signature 461 477 2.6E-37 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21045 d21393ed9e784c1ccb254b79f8eabf2f 554 PRINTS PR00738 Glycosyl hydrolase family 20 signature 173 194 2.6E-37 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21045 d21393ed9e784c1ccb254b79f8eabf2f 554 PRINTS PR00738 Glycosyl hydrolase family 20 signature 295 313 2.6E-37 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21045 d21393ed9e784c1ccb254b79f8eabf2f 554 PRINTS PR00738 Glycosyl hydrolase family 20 signature 100 120 2.6E-37 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21045 d21393ed9e784c1ccb254b79f8eabf2f 554 PRINTS PR00738 Glycosyl hydrolase family 20 signature 479 496 2.6E-37 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21045 d21393ed9e784c1ccb254b79f8eabf2f 554 PRINTS PR00738 Glycosyl hydrolase family 20 signature 317 330 2.6E-37 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS21045 d21393ed9e784c1ccb254b79f8eabf2f 554 Gene3D G3DSA:3.20.20.80 148 531 1.4E-137 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS21045 d21393ed9e784c1ccb254b79f8eabf2f 554 SUPERFAMILY SSF51445 150 513 1.23E-117 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS21045 d21393ed9e784c1ccb254b79f8eabf2f 554 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 150 497 1.3E-121 T 06-07-2017 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 SMD11_RS21045 d21393ed9e784c1ccb254b79f8eabf2f 554 Gene3D G3DSA:3.30.379.10 2 147 5.1E-25 T 06-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS18025 0c199deeb53dce4473ef2fef0247ad9f 561 Gene3D G3DSA:3.40.50.300 52 272 1.2E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18025 0c199deeb53dce4473ef2fef0247ad9f 561 SUPERFAMILY SSF52540 136 416 2.52E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18025 0c199deeb53dce4473ef2fef0247ad9f 561 Pfam PF00271 Helicase conserved C-terminal domain 298 398 2.1E-23 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS18025 0c199deeb53dce4473ef2fef0247ad9f 561 SMART SM00490 317 398 1.4E-27 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS18025 0c199deeb53dce4473ef2fef0247ad9f 561 SMART SM00487 83 283 2.0E-50 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS18025 0c199deeb53dce4473ef2fef0247ad9f 561 Pfam PF00270 DEAD/DEAH box helicase 88 257 1.9E-43 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD11_RS18025 0c199deeb53dce4473ef2fef0247ad9f 561 Gene3D G3DSA:3.40.50.300 273 422 2.2E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02320 76def62e90cd7d0b4a0e128894f2288f 287 SUPERFAMILY SSF53474 2 273 1.29E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS02320 76def62e90cd7d0b4a0e128894f2288f 287 Gene3D G3DSA:3.40.50.1820 4 275 1.1E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS02320 76def62e90cd7d0b4a0e128894f2288f 287 Pfam PF00561 alpha/beta hydrolase fold 21 122 7.1E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS11600 caa841976f839ec6236484d41383bc24 1171 Pfam PF12705 PD-(D/E)XK nuclease superfamily 972 1147 2.3E-10 T 06-07-2017 SMD11_RS11600 caa841976f839ec6236484d41383bc24 1171 Gene3D G3DSA:1.10.486.10 470 642 1.8E-23 T 06-07-2017 SMD11_RS11600 caa841976f839ec6236484d41383bc24 1171 Gene3D G3DSA:3.40.50.300 357 469 4.2E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11600 caa841976f839ec6236484d41383bc24 1171 Gene3D G3DSA:3.40.50.300 664 699 4.2E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11600 caa841976f839ec6236484d41383bc24 1171 Gene3D G3DSA:3.40.50.300 740 789 4.2E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11600 caa841976f839ec6236484d41383bc24 1171 SUPERFAMILY SSF52540 744 789 3.49E-114 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11600 caa841976f839ec6236484d41383bc24 1171 SUPERFAMILY SSF52540 546 703 3.49E-114 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11600 caa841976f839ec6236484d41383bc24 1171 SUPERFAMILY SSF52540 33 505 3.49E-114 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11600 caa841976f839ec6236484d41383bc24 1171 Pfam PF00580 UvrD/REP helicase N-terminal domain 36 338 3.1E-49 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 SMD11_RS11600 caa841976f839ec6236484d41383bc24 1171 Pfam PF13361 UvrD-like helicase C-terminal domain 569 762 9.5E-12 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMD11_RS11600 caa841976f839ec6236484d41383bc24 1171 Pfam PF13361 UvrD-like helicase C-terminal domain 354 506 9.3E-13 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMD11_RS11600 caa841976f839ec6236484d41383bc24 1171 SUPERFAMILY SSF52980 995 1138 5.9E-6 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD11_RS11600 caa841976f839ec6236484d41383bc24 1171 Gene3D G3DSA:3.40.50.300 224 343 5.1E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11600 caa841976f839ec6236484d41383bc24 1171 Gene3D G3DSA:3.40.50.300 35 171 5.1E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28470 5e8d6319164394e9e1aa5728719c75ba 350 Pfam PF00534 Glycosyl transferases group 1 214 305 5.2E-11 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 SMD11_RS28470 5e8d6319164394e9e1aa5728719c75ba 350 Pfam PF13439 Glycosyltransferase Family 4 17 152 1.7E-7 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 SMD11_RS28470 5e8d6319164394e9e1aa5728719c75ba 350 Gene3D G3DSA:3.40.50.2000 210 305 6.2E-15 T 06-07-2017 SMD11_RS28470 5e8d6319164394e9e1aa5728719c75ba 350 SUPERFAMILY SSF53756 1 307 1.61E-37 T 06-07-2017 SMD11_RS06930 23fadde9a663d1090d306494834a6fe0 516 Pfam PF03606 C4-dicarboxylate anaerobic carrier 31 511 2.4E-101 T 06-07-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 SMD11_RS02545 0840595fda7f3831a655e50a42293dc9 227 Gene3D G3DSA:1.10.10.10 144 223 7.2E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02545 0840595fda7f3831a655e50a42293dc9 227 Gene3D G3DSA:2.60.120.10 7 136 1.3E-25 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS02545 0840595fda7f3831a655e50a42293dc9 227 SMART SM00419 166 215 9.1E-6 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMD11_RS02545 0840595fda7f3831a655e50a42293dc9 227 Pfam PF00027 Cyclic nucleotide-binding domain 29 114 5.8E-16 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain SMD11_RS02545 0840595fda7f3831a655e50a42293dc9 227 SMART SM00100 9 127 3.5E-16 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain SMD11_RS02545 0840595fda7f3831a655e50a42293dc9 227 Pfam PF13545 Crp-like helix-turn-helix domain 147 220 1.1E-13 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMD11_RS02545 0840595fda7f3831a655e50a42293dc9 227 SUPERFAMILY SSF51206 7 136 4.84E-25 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like SMD11_RS02545 0840595fda7f3831a655e50a42293dc9 227 SUPERFAMILY SSF46785 144 223 8.94E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17960 188ed25c7a92e6d4ba082823037fd3ee 68 SUPERFAMILY SSF46955 11 59 2.61E-11 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS17960 188ed25c7a92e6d4ba082823037fd3ee 68 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 11 58 1.2E-8 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMD11_RS17960 188ed25c7a92e6d4ba082823037fd3ee 68 Pfam PF12728 Helix-turn-helix domain 11 59 1.3E-11 T 06-07-2017 SMD11_RS17960 188ed25c7a92e6d4ba082823037fd3ee 68 Gene3D G3DSA:1.10.1660.10 11 57 5.4E-7 T 06-07-2017 SMD11_RS14785 ee238386501b94cd87376a9a1a9ae99b 153 SUPERFAMILY SSF54593 1 139 5.1E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS14785 ee238386501b94cd87376a9a1a9ae99b 153 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 132 4.4E-13 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS14785 ee238386501b94cd87376a9a1a9ae99b 153 Gene3D G3DSA:3.10.180.10 2 138 3.3E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS15825 811c4f2f2853c31c8bf16d270cd4c67f 173 Pfam PF14437 MafB19-like deaminase 29 173 9.7E-31 T 06-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 SMD11_RS15825 811c4f2f2853c31c8bf16d270cd4c67f 173 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 78 115 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SMD11_RS15825 811c4f2f2853c31c8bf16d270cd4c67f 173 Gene3D G3DSA:3.40.140.10 30 171 4.3E-58 T 06-07-2017 SMD11_RS15825 811c4f2f2853c31c8bf16d270cd4c67f 173 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 32 171 45.376 T 06-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 SMD11_RS15825 811c4f2f2853c31c8bf16d270cd4c67f 173 SUPERFAMILY SSF53927 26 171 4.35E-52 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 SMD11_RS09285 80790cc643fdd9d3e56d29d7156d737b 281 Pfam PF13312 Domain of unknown function (DUF4081) 48 152 2.4E-44 T 06-07-2017 IPR025289 Domain of unknown function DUF4081 SMD11_RS09285 80790cc643fdd9d3e56d29d7156d737b 281 Gene3D G3DSA:3.40.630.30 132 277 5.1E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS09285 80790cc643fdd9d3e56d29d7156d737b 281 SUPERFAMILY SSF55729 9 276 4.96E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS09285 80790cc643fdd9d3e56d29d7156d737b 281 Pfam PF00583 Acetyltransferase (GNAT) family 208 271 1.2E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS09285 80790cc643fdd9d3e56d29d7156d737b 281 PIRSF PIRSF021603 1 281 5.5E-137 T 06-07-2017 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like SMD11_RS09915 ea659289e7fe22848fca10d174065821 65 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 5 63 1.1E-14 T 06-07-2017 IPR032716 Acyl-CoA carboxylase epsilon subunit SMD11_RS28755 485706e8656163579aabca01b97ca608 293 Gene3D G3DSA:3.20.20.30 4 289 1.9E-57 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS28755 485706e8656163579aabca01b97ca608 293 SUPERFAMILY SSF51679 4 290 4.32E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS28755 485706e8656163579aabca01b97ca608 293 TIGRFAM TIGR03621 F420_MSMEG_2516: probable F420-dependent oxidoreductase, MSMEG_2516 family 5 291 7.8E-109 T 06-07-2017 IPR019923 Luciferase-like, F420-dependent oxidoreductase, MSMEG2516, predicted SMD11_RS28755 485706e8656163579aabca01b97ca608 293 Pfam PF00296 Luciferase-like monooxygenase 14 236 1.4E-34 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS26425 b06d0245740ff032ed44ad25ec411ce2 508 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 9 503 8.7E-228 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMD11_RS26425 b06d0245740ff032ed44ad25ec411ce2 508 SUPERFAMILY SSF53067 10 261 3.48E-93 T 06-07-2017 SMD11_RS26425 b06d0245740ff032ed44ad25ec411ce2 508 Hamap MF_00186 Glycerol kinase [glpK]. 8 504 56.046 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMD11_RS26425 b06d0245740ff032ed44ad25ec411ce2 508 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 140 152 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD11_RS26425 b06d0245740ff032ed44ad25ec411ce2 508 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 11 258 5.1E-82 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMD11_RS26425 b06d0245740ff032ed44ad25ec411ce2 508 PIRSF PIRSF000538 8 508 1.1E-167 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD11_RS26425 b06d0245740ff032ed44ad25ec411ce2 508 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 369 389 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD11_RS26425 b06d0245740ff032ed44ad25ec411ce2 508 Gene3D G3DSA:3.30.420.40 261 505 9.6E-102 T 06-07-2017 SMD11_RS26425 b06d0245740ff032ed44ad25ec411ce2 508 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 267 457 5.6E-64 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMD11_RS26425 b06d0245740ff032ed44ad25ec411ce2 508 SUPERFAMILY SSF53067 261 504 1.15E-81 T 06-07-2017 SMD11_RS26425 b06d0245740ff032ed44ad25ec411ce2 508 Gene3D G3DSA:3.30.420.40 7 259 1.1E-108 T 06-07-2017 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 432 2.5E-150 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 316 338 4.7E-107 T 06-07-2017 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 157 182 4.7E-107 T 06-07-2017 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 113 136 4.7E-107 T 06-07-2017 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 183 206 4.7E-107 T 06-07-2017 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 72 92 4.7E-107 T 06-07-2017 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 371 389 4.7E-107 T 06-07-2017 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 405 423 4.7E-107 T 06-07-2017 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 4.7E-107 T 06-07-2017 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 274 293 4.7E-107 T 06-07-2017 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 PIRSF PIRSF004557 1 437 3.2E-125 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 06-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 436 29.784 T 06-07-2017 IPR026593 Protein translocase subunit SecY SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 SUPERFAMILY SSF103491 2 427 3.01E-128 T 06-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 Pfam PF00344 SecY translocase 73 420 5.3E-119 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 Gene3D G3DSA:1.10.3370.10 2 437 2.0E-159 T 06-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD11_RS18990 ddb363eb8ccf3318450b55364d250d70 437 ProSitePatterns PS00756 Protein secY signature 2. 176 193 - T 06-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD11_RS26340 f48f9abb6b3f12051a28d70c84fff12f 880 SUPERFAMILY SSF52540 607 668 1.29E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26340 f48f9abb6b3f12051a28d70c84fff12f 880 SUPERFAMILY SSF52540 709 852 1.29E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26340 f48f9abb6b3f12051a28d70c84fff12f 880 Pfam PF14490 Helix-hairpin-helix containing domain 164 249 1.6E-10 T 06-07-2017 IPR029493 RecD helicase-like helix-hairpin-helix domain SMD11_RS26340 f48f9abb6b3f12051a28d70c84fff12f 880 Gene3D G3DSA:3.40.50.300 611 739 2.5E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26340 f48f9abb6b3f12051a28d70c84fff12f 880 Gene3D G3DSA:3.40.50.300 786 847 2.5E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14560 6d7de9d6b0888100d837337524067361 355 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 154 353 1.7E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS14560 6d7de9d6b0888100d837337524067361 355 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 81 347 5.8E-87 T 06-07-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 SMD11_RS14560 6d7de9d6b0888100d837337524067361 355 SUPERFAMILY SSF161098 88 342 3.4E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS14560 6d7de9d6b0888100d837337524067361 355 Gene3D G3DSA:1.10.3720.10 79 349 6.0E-44 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS30585 f21b9641681c501bb1b160a3703045a6 266 Gene3D G3DSA:3.40.630.30 135 258 4.8E-13 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS30585 f21b9641681c501bb1b160a3703045a6 266 SUPERFAMILY SSF55729 135 265 2.66E-15 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS30585 f21b9641681c501bb1b160a3703045a6 266 Pfam PF13673 Acetyltransferase (GNAT) domain 174 258 7.7E-6 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS13320 e7b6f9b8d21c3cfad18b8d7bcc81ce29 609 Pfam PF00069 Protein kinase domain 67 318 9.7E-46 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS13320 e7b6f9b8d21c3cfad18b8d7bcc81ce29 609 SUPERFAMILY SSF56112 63 326 8.15E-69 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS13320 e7b6f9b8d21c3cfad18b8d7bcc81ce29 609 Gene3D G3DSA:1.10.510.10 137 325 1.6E-47 T 06-07-2017 SMD11_RS13320 e7b6f9b8d21c3cfad18b8d7bcc81ce29 609 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 73 96 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS13320 e7b6f9b8d21c3cfad18b8d7bcc81ce29 609 SMART SM00220 67 325 3.2E-60 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS13320 e7b6f9b8d21c3cfad18b8d7bcc81ce29 609 Gene3D G3DSA:3.30.200.20 59 136 1.0E-23 T 06-07-2017 SMD11_RS13320 e7b6f9b8d21c3cfad18b8d7bcc81ce29 609 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 189 201 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS00670 f46176f51f54fc138c3b3a7169910af0 395 Gene3D G3DSA:2.40.110.10 141 236 1.0E-29 T 06-07-2017 SMD11_RS00670 f46176f51f54fc138c3b3a7169910af0 395 Gene3D G3DSA:1.20.140.10 237 392 2.2E-9 T 06-07-2017 SMD11_RS00670 f46176f51f54fc138c3b3a7169910af0 395 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 143 155 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD11_RS00670 f46176f51f54fc138c3b3a7169910af0 395 SUPERFAMILY SSF56645 17 257 2.62E-64 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS00670 f46176f51f54fc138c3b3a7169910af0 395 SUPERFAMILY SSF47203 287 390 2.3E-5 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS00670 f46176f51f54fc138c3b3a7169910af0 395 Gene3D G3DSA:1.10.540.10 17 137 1.2E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS00670 f46176f51f54fc138c3b3a7169910af0 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 142 232 1.1E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS00670 f46176f51f54fc138c3b3a7169910af0 395 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 284 392 4.2E-5 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS00670 f46176f51f54fc138c3b3a7169910af0 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 136 2.6E-22 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS17450 2bab2857f0c4bd2fe8ec80029694a0a9 608 SUPERFAMILY SSF52540 154 581 4.93E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17450 2bab2857f0c4bd2fe8ec80029694a0a9 608 Gene3D G3DSA:3.40.50.300 163 246 5.0E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17450 2bab2857f0c4bd2fe8ec80029694a0a9 608 Gene3D G3DSA:3.40.50.300 385 583 5.0E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17450 2bab2857f0c4bd2fe8ec80029694a0a9 608 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 183 586 7.3E-35 T 06-07-2017 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 SMD11_RS25735 7413bb4353a2a211c53d54509a598dd1 348 SUPERFAMILY SSF81345 24 343 1.27E-79 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS25735 7413bb4353a2a211c53d54509a598dd1 348 Gene3D G3DSA:1.10.3470.10 24 344 7.2E-99 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS25735 7413bb4353a2a211c53d54509a598dd1 348 Pfam PF01032 FecCD transport family 35 342 3.0E-91 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD11_RS11885 4ab300f6c55c732ad829310ac17b2abf 365 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 8 363 2.9E-183 T 06-07-2017 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria SMD11_RS11885 4ab300f6c55c732ad829310ac17b2abf 365 Pfam PF00155 Aminotransferase class I and II 30 363 5.0E-43 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS11885 4ab300f6c55c732ad829310ac17b2abf 365 Gene3D G3DSA:3.90.1150.10 242 364 1.7E-21 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS11885 4ab300f6c55c732ad829310ac17b2abf 365 Gene3D G3DSA:3.40.640.10 44 241 1.6E-39 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS11885 4ab300f6c55c732ad829310ac17b2abf 365 SUPERFAMILY SSF53383 10 365 2.64E-77 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS15380 cd3a91ceeef7905a67424de3882f581b 147 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 8 122 1.5E-31 T 06-07-2017 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III SMD11_RS20615 a7b3b686150b991a1f083664373c8e66 430 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 185 338 2.3E-40 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS20615 a7b3b686150b991a1f083664373c8e66 430 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 185 338 1.9E-45 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS02865 f9979ed12e11c97b9cbb9c557043c9a8 54 SUPERFAMILY SSF69047 5 51 1.57E-9 T 06-07-2017 IPR008462 CsbD-like SMD11_RS02865 f9979ed12e11c97b9cbb9c557043c9a8 54 Pfam PF05532 CsbD-like 4 54 1.0E-15 T 06-07-2017 IPR008462 CsbD-like SMD11_RS02865 f9979ed12e11c97b9cbb9c557043c9a8 54 Gene3D G3DSA:1.10.1470.10 5 53 1.3E-13 T 06-07-2017 IPR008462 CsbD-like SMD11_RS29250 331a2abde91816be5c396e34f21d7dfe 171 Gene3D G3DSA:3.40.50.620 4 148 6.5E-32 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS29250 331a2abde91816be5c396e34f21d7dfe 171 Pfam PF00582 Universal stress protein family 6 147 1.3E-23 T 06-07-2017 IPR006016 UspA GO:0006950 SMD11_RS29250 331a2abde91816be5c396e34f21d7dfe 171 SUPERFAMILY SSF52402 6 148 5.19E-29 T 06-07-2017 SMD11_RS29250 331a2abde91816be5c396e34f21d7dfe 171 PRINTS PR01438 Universal stress protein signature 125 147 4.5E-14 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS29250 331a2abde91816be5c396e34f21d7dfe 171 PRINTS PR01438 Universal stress protein signature 5 23 4.5E-14 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS29250 331a2abde91816be5c396e34f21d7dfe 171 PRINTS PR01438 Universal stress protein signature 107 119 4.5E-14 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS27255 5ee87bcf0147f246bebf7a66dec3c405 204 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 6 204 6.7E-60 T 06-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMD11_RS27255 5ee87bcf0147f246bebf7a66dec3c405 204 Gene3D G3DSA:1.10.1050.10 5 97 4.2E-27 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 SMD11_RS27255 5ee87bcf0147f246bebf7a66dec3c405 204 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 204 28.962 T 06-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 SMD11_RS27255 5ee87bcf0147f246bebf7a66dec3c405 204 Gene3D G3DSA:3.10.290.10 98 188 3.7E-23 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 SMD11_RS27255 5ee87bcf0147f246bebf7a66dec3c405 204 SMART SM01390 3 91 1.2E-31 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 SMD11_RS27255 5ee87bcf0147f246bebf7a66dec3c405 204 Pfam PF01479 S4 domain 92 139 5.5E-17 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 SMD11_RS27255 5ee87bcf0147f246bebf7a66dec3c405 204 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 06-07-2017 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS27255 5ee87bcf0147f246bebf7a66dec3c405 204 SMART SM00363 92 152 2.4E-14 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 SMD11_RS27255 5ee87bcf0147f246bebf7a66dec3c405 204 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 6 91 1.2E-17 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 SMD11_RS27255 5ee87bcf0147f246bebf7a66dec3c405 204 SUPERFAMILY SSF55174 6 204 9.42E-54 T 06-07-2017 SMD11_RS01230 4c04793a8e0f58af126f66a10ae59052 538 SUPERFAMILY SSF56300 161 508 3.41E-27 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS01230 4c04793a8e0f58af126f66a10ae59052 538 Pfam PF09423 PhoD-like phosphatase 167 507 6.0E-105 T 06-07-2017 IPR018946 Alkaline phosphatase D-related SMD11_RS01230 4c04793a8e0f58af126f66a10ae59052 538 Gene3D G3DSA:3.60.21.10 179 509 1.5E-11 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS01230 4c04793a8e0f58af126f66a10ae59052 538 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 55 152 3.4E-31 T 06-07-2017 IPR032093 Phospholipase D, N-terminal SMD11_RS32555 2dd42c5340008ed74c1cbe07fefb5f6a 525 SUPERFAMILY SSF56112 177 406 4.96E-12 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS32555 2dd42c5340008ed74c1cbe07fefb5f6a 525 Gene3D G3DSA:3.90.1200.10 314 428 6.6E-5 T 06-07-2017 SMD11_RS32555 2dd42c5340008ed74c1cbe07fefb5f6a 525 Pfam PF01636 Phosphotransferase enzyme family 225 419 3.0E-8 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase SMD11_RS27500 9ae1679b0f9b74b8a05e63de97c8f102 206 SUPERFAMILY SSF63380 92 194 2.04E-32 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD11_RS27500 9ae1679b0f9b74b8a05e63de97c8f102 206 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 2 195 1.7E-59 T 06-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD11_RS27500 9ae1679b0f9b74b8a05e63de97c8f102 206 PIRSF PIRSF000498 1 202 4.7E-68 T 06-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD11_RS27500 9ae1679b0f9b74b8a05e63de97c8f102 206 Gene3D G3DSA:2.40.30.20 104 198 1.8E-29 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 SMD11_RS27500 9ae1679b0f9b74b8a05e63de97c8f102 206 Gene3D G3DSA:2.40.30.20 5 103 2.5E-32 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 SMD11_RS27500 9ae1679b0f9b74b8a05e63de97c8f102 206 Pfam PF00677 Lumazine binding domain 99 183 6.3E-23 T 06-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD11_RS27500 9ae1679b0f9b74b8a05e63de97c8f102 206 Pfam PF00677 Lumazine binding domain 3 85 6.1E-22 T 06-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD11_RS27500 9ae1679b0f9b74b8a05e63de97c8f102 206 SUPERFAMILY SSF63380 2 87 1.28E-23 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD11_RS01970 e99fbfb565df163322ff6b9655935aac 762 Pfam PF03176 MMPL family 67 407 2.2E-54 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 SMD11_RS01970 e99fbfb565df163322ff6b9655935aac 762 Pfam PF03176 MMPL family 486 743 1.1E-28 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 SMD11_RS01970 e99fbfb565df163322ff6b9655935aac 762 SUPERFAMILY SSF82866 519 741 1.16E-22 T 06-07-2017 SMD11_RS01970 e99fbfb565df163322ff6b9655935aac 762 Gene3D G3DSA:1.20.1640.10 544 747 7.0E-26 T 06-07-2017 SMD11_RS01970 e99fbfb565df163322ff6b9655935aac 762 Gene3D G3DSA:1.20.1640.10 184 368 1.4E-26 T 06-07-2017 SMD11_RS01970 e99fbfb565df163322ff6b9655935aac 762 SUPERFAMILY SSF82866 149 364 1.31E-28 T 06-07-2017 SMD11_RS07850 bffba27887a464a2c854cd53ddb8a012 1279 SUPERFAMILY SSF49503 578 703 3.9E-10 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS07850 bffba27887a464a2c854cd53ddb8a012 1279 ProSitePatterns PS00080 Multicopper oxidases signature 2. 405 416 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 SMD11_RS07850 bffba27887a464a2c854cd53ddb8a012 1279 Pfam PF07732 Multicopper oxidase 87 180 8.8E-8 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 SMD11_RS07850 bffba27887a464a2c854cd53ddb8a012 1279 Pfam PF07732 Multicopper oxidase 662 701 2.5E-4 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 SMD11_RS07850 bffba27887a464a2c854cd53ddb8a012 1279 Gene3D G3DSA:2.60.40.420 325 423 8.0E-11 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS07850 bffba27887a464a2c854cd53ddb8a012 1279 Gene3D G3DSA:2.60.40.420 1182 1276 3.2E-7 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS07850 bffba27887a464a2c854cd53ddb8a012 1279 Gene3D G3DSA:2.60.40.420 942 1100 1.2E-20 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS07850 bffba27887a464a2c854cd53ddb8a012 1279 Gene3D G3DSA:2.60.40.420 17 186 8.5E-21 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS07850 bffba27887a464a2c854cd53ddb8a012 1279 Gene3D G3DSA:2.60.40.420 567 706 4.2E-12 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS07850 bffba27887a464a2c854cd53ddb8a012 1279 SUPERFAMILY SSF49503 941 1102 4.89E-16 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS07850 bffba27887a464a2c854cd53ddb8a012 1279 Gene3D G3DSA:2.60.40.420 777 871 8.1E-5 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS07850 bffba27887a464a2c854cd53ddb8a012 1279 SUPERFAMILY SSF49503 324 424 3.63E-14 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS07850 bffba27887a464a2c854cd53ddb8a012 1279 SUPERFAMILY SSF49503 824 919 2.51E-6 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS07850 bffba27887a464a2c854cd53ddb8a012 1279 SUPERFAMILY SSF49503 18 182 1.26E-12 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS07850 bffba27887a464a2c854cd53ddb8a012 1279 SUPERFAMILY SSF49503 1159 1277 1.44E-9 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 SUPERFAMILY SSF158832 7 326 7.06E-111 T 06-07-2017 SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 SUPERFAMILY SSF50249 643 730 4.7E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 SMART SM00316 655 726 8.3E-25 T 06-07-2017 IPR022967 RNA-binding domain, S1 SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 SUPERFAMILY SSF53098 327 475 4.55E-50 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 SUPERFAMILY SSF47781 566 637 3.56E-19 T 06-07-2017 IPR010994 RuvA domain 2-like SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 Gene3D G3DSA:1.10.3500.10 113 327 3.3E-98 T 06-07-2017 IPR023323 Tex-like domain SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 Gene3D G3DSA:1.10.3500.10 457 504 3.3E-98 T 06-07-2017 IPR023323 Tex-like domain SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 Pfam PF12836 Helix-hairpin-helix motif 497 561 6.2E-28 T 06-07-2017 SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 Gene3D G3DSA:1.10.150.310 505 636 1.5E-44 T 06-07-2017 IPR023097 Tex RuvX-like domain SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 SUPERFAMILY SSF47781 476 564 1.56E-26 T 06-07-2017 IPR010994 RuvA domain 2-like SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 Pfam PF00575 S1 RNA binding domain 656 726 9.3E-18 T 06-07-2017 IPR003029 S1 domain GO:0003676 SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 SMART SM00732 331 430 8.2E-39 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 Pfam PF16921 Tex protein YqgF-like domain 332 457 6.6E-51 T 06-07-2017 IPR032639 Tex protein, YqgF-like domain SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 Gene3D G3DSA:3.30.420.140 331 456 8.7E-51 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 Gene3D G3DSA:1.10.10.650 7 112 2.9E-42 T 06-07-2017 IPR023319 Tex-like protein, HTH domain SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 Pfam PF09371 Tex-like protein N-terminal domain 12 195 2.8E-64 T 06-07-2017 IPR018974 Tex-like protein, N-terminal SMD11_RS05445 acb1b9a79e5343102016b1b38784cd42 790 Gene3D G3DSA:2.40.50.140 647 726 6.2E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS25055 30c5315a591e6990e67ea14294e4fd27 218 SUPERFAMILY SSF56281 22 214 8.12E-43 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS25055 30c5315a591e6990e67ea14294e4fd27 218 SMART SM00849 32 197 1.8E-28 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS25055 30c5315a591e6990e67ea14294e4fd27 218 Gene3D G3DSA:3.60.15.10 24 199 1.3E-45 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS25055 30c5315a591e6990e67ea14294e4fd27 218 Pfam PF00753 Metallo-beta-lactamase superfamily 29 197 3.1E-11 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 324 505 0.0015 T 06-07-2017 SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 SUPERFAMILY SSF51735 321 586 2.33E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 Gene3D G3DSA:3.40.50.720 323 563 1.2E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 Pfam PF00561 alpha/beta hydrolase fold 31 152 1.3E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 400 411 6.0E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 495 512 6.0E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 448 464 6.0E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 325 342 6.0E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 474 493 6.0E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 Pfam PF00106 short chain dehydrogenase 325 515 1.9E-54 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 Gene3D G3DSA:3.40.50.1820 6 297 2.0E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 400 411 1.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 474 493 1.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 454 462 1.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 SUPERFAMILY SSF53474 8 297 2.57E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS16505 3576bc1179e25e2ad8b57fd199681414 591 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 461 489 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS09150 c0c3436b93390139162ed22a3a24bdf2 284 Pfam PF13560 Helix-turn-helix domain 13 70 4.3E-11 T 06-07-2017 SMD11_RS09150 c0c3436b93390139162ed22a3a24bdf2 284 SUPERFAMILY SSF47413 11 74 8.7E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS09150 c0c3436b93390139162ed22a3a24bdf2 284 SMART SM00530 17 72 2.1E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS09150 c0c3436b93390139162ed22a3a24bdf2 284 Gene3D G3DSA:1.10.260.40 6 74 2.1E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS33810 6f2e74bec163b4d22ad3397b15b66260 217 SMART SM01110 31 201 0.0013 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 SMD11_RS33810 6f2e74bec163b4d22ad3397b15b66260 217 Pfam PF01083 Cutinase 59 182 5.6E-9 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 SMD11_RS33810 6f2e74bec163b4d22ad3397b15b66260 217 SUPERFAMILY SSF53474 32 184 1.1E-13 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS33810 6f2e74bec163b4d22ad3397b15b66260 217 Gene3D G3DSA:3.40.50.1820 22 195 6.8E-17 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 Gene3D G3DSA:3.30.1360.30 283 409 4.7E-42 T 06-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 SUPERFAMILY SSF55681 117 298 1.93E-93 T 06-07-2017 SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 SUPERFAMILY SSF55681 422 582 1.93E-93 T 06-07-2017 SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 Pfam PF01336 OB-fold nucleic acid binding domain 21 104 1.4E-15 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 Gene3D G3DSA:3.30.930.10 136 282 1.5E-98 T 06-07-2017 SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 Gene3D G3DSA:3.30.930.10 410 583 1.5E-98 T 06-07-2017 SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 4 561 33.155 T 06-07-2017 SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 Pfam PF02938 GAD domain 315 403 1.4E-19 T 06-07-2017 IPR029351 GAD domain Reactome: R-HSA-379726 SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 555 2.3E-95 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 1.3E-21 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 516 530 1.3E-21 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 1.3E-21 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 472 488 1.3E-21 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 SUPERFAMILY SSF50249 4 107 1.81E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 Gene3D G3DSA:2.40.50.140 4 108 4.4E-34 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 SUPERFAMILY SSF55261 297 414 6.7E-34 T 06-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 SMD11_RS17330 acf76ceb3c9b5fa542e02bb51374d9d7 591 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 582 1.1E-186 T 06-07-2017 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 SMD11_RS15960 3177f4a3b05c1842ffd9d62ebebb6d78 531 SUPERFAMILY SSF51905 270 380 6.02E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15960 3177f4a3b05c1842ffd9d62ebebb6d78 531 SUPERFAMILY SSF51905 8 184 6.02E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15960 3177f4a3b05c1842ffd9d62ebebb6d78 531 Gene3D G3DSA:3.50.50.60 281 321 4.8E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15960 3177f4a3b05c1842ffd9d62ebebb6d78 531 Gene3D G3DSA:3.50.50.60 5 174 4.8E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15960 3177f4a3b05c1842ffd9d62ebebb6d78 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 2.4E-41 T 06-07-2017 SMD11_RS15960 3177f4a3b05c1842ffd9d62ebebb6d78 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 2.4E-41 T 06-07-2017 SMD11_RS15960 3177f4a3b05c1842ffd9d62ebebb6d78 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 2.4E-41 T 06-07-2017 SMD11_RS15960 3177f4a3b05c1842ffd9d62ebebb6d78 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 334 2.4E-41 T 06-07-2017 SMD11_RS15960 3177f4a3b05c1842ffd9d62ebebb6d78 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 350 2.4E-41 T 06-07-2017 SMD11_RS15960 3177f4a3b05c1842ffd9d62ebebb6d78 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 2.4E-41 T 06-07-2017 SMD11_RS15960 3177f4a3b05c1842ffd9d62ebebb6d78 531 Gene3D G3DSA:3.30.9.10 331 347 3.6E-12 T 06-07-2017 SMD11_RS15960 3177f4a3b05c1842ffd9d62ebebb6d78 531 Gene3D G3DSA:3.30.9.10 175 276 3.6E-12 T 06-07-2017 SMD11_RS15960 3177f4a3b05c1842ffd9d62ebebb6d78 531 Pfam PF01494 FAD binding domain 8 347 2.1E-69 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS27995 57362df02c375edfd0f9086463b3fad5 287 SUPERFAMILY SSF50891 175 286 6.07E-11 T 06-07-2017 IPR029000 Cyclophilin-like domain SMD11_RS27995 57362df02c375edfd0f9086463b3fad5 287 Gene3D G3DSA:2.40.100.10 176 286 2.9E-7 T 06-07-2017 IPR029000 Cyclophilin-like domain SMD11_RS27995 57362df02c375edfd0f9086463b3fad5 287 Pfam PF02626 Allophanate hydrolase subunit 2 26 283 5.7E-79 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B SMD11_RS27995 57362df02c375edfd0f9086463b3fad5 287 SMART SM00797 25 287 5.3E-86 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B SMD11_RS27995 57362df02c375edfd0f9086463b3fad5 287 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 4 286 1.5E-77 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B SMD11_RS09455 33d46d382737577084b782cb56ceecbc 459 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 257 294 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS09455 33d46d382737577084b782cb56ceecbc 459 Gene3D G3DSA:3.40.640.10 71 344 2.4E-87 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS09455 33d46d382737577084b782cb56ceecbc 459 Pfam PF00202 Aminotransferase class-III 35 449 1.1E-103 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS09455 33d46d382737577084b782cb56ceecbc 459 Gene3D G3DSA:3.90.1150.10 9 69 9.0E-34 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS09455 33d46d382737577084b782cb56ceecbc 459 Gene3D G3DSA:3.90.1150.10 346 454 9.0E-34 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS09455 33d46d382737577084b782cb56ceecbc 459 SUPERFAMILY SSF53383 15 454 2.67E-128 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS19190 f859c95a349418faa20e0eb22e8d7a00 215 Pfam PF00583 Acetyltransferase (GNAT) family 107 178 1.5E-15 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS19190 f859c95a349418faa20e0eb22e8d7a00 215 Gene3D G3DSA:3.40.630.30 4 56 3.2E-33 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS19190 f859c95a349418faa20e0eb22e8d7a00 215 Gene3D G3DSA:3.40.630.30 104 199 3.2E-33 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS19190 f859c95a349418faa20e0eb22e8d7a00 215 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 105 197 5.9E-26 T 06-07-2017 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 SMD11_RS19190 f859c95a349418faa20e0eb22e8d7a00 215 SUPERFAMILY SSF55729 103 187 5.83E-29 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS19190 f859c95a349418faa20e0eb22e8d7a00 215 SUPERFAMILY SSF55729 2 61 5.83E-29 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS33040 6c869ee4963a242ebea4cc88ac0c8fe0 118 Gene3D G3DSA:2.30.30.40 48 118 1.6E-32 T 06-07-2017 SMD11_RS33040 6c869ee4963a242ebea4cc88ac0c8fe0 118 Pfam PF08274 PhnA Zinc-Ribbon 4 33 3.5E-14 T 06-07-2017 IPR013987 PhnA protein, N-terminal SMD11_RS33040 6c869ee4963a242ebea4cc88ac0c8fe0 118 Gene3D G3DSA:2.20.25.10 3 40 9.8E-20 T 06-07-2017 SMD11_RS33040 6c869ee4963a242ebea4cc88ac0c8fe0 118 Pfam PF03831 PhnA domain 49 118 3.3E-31 T 06-07-2017 IPR013988 PhnA protein, C-terminal SMD11_RS33040 6c869ee4963a242ebea4cc88ac0c8fe0 118 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 5 118 2.8E-37 T 06-07-2017 IPR004624 PhnA protein SMD11_RS33040 6c869ee4963a242ebea4cc88ac0c8fe0 118 SUPERFAMILY SSF82057 45 118 3.71E-24 T 06-07-2017 SMD11_RS33040 6c869ee4963a242ebea4cc88ac0c8fe0 118 SUPERFAMILY SSF57783 4 38 2.89E-13 T 06-07-2017 SMD11_RS25920 bb0a62ced1fb0a63c5a2fb30c71a54bc 66 Pfam PF05120 Gas vesicle protein G 4 62 6.1E-18 T 06-07-2017 IPR007804 Gas vesicle protein GvpG SMD11_RS25865 a0a10cc475984997b245877cccbf37ee 213 Gene3D G3DSA:3.40.1130.10 32 149 1.3E-14 T 06-07-2017 SMD11_RS25865 a0a10cc475984997b245877cccbf37ee 213 SUPERFAMILY SSF69593 16 184 9.42E-31 T 06-07-2017 SMD11_RS25865 a0a10cc475984997b245877cccbf37ee 213 Pfam PF01553 Acyltransferase 27 146 6.3E-18 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD11_RS25865 a0a10cc475984997b245877cccbf37ee 213 SMART SM00563 39 149 1.8E-22 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD11_RS17910 741a1c84e958228d31c28028627a15db 105 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 104 6.0E-42 T 06-07-2017 IPR024412 Lsr2 SMD11_RS17910 741a1c84e958228d31c28028627a15db 105 Pfam PF11774 Lsr2 2 104 6.8E-36 T 06-07-2017 IPR024412 Lsr2 SMD11_RS12075 6c6028f003c7b452cd62d4409d1f6d65 555 Pfam PF13520 Amino acid permease 15 426 3.8E-49 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS12075 6c6028f003c7b452cd62d4409d1f6d65 555 PIRSF PIRSF006060 2 464 4.8E-76 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS01210 a70dbd114385fccfbeb46ad508448f00 378 Pfam PF00487 Fatty acid desaturase 63 310 1.2E-37 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 SMD11_RS06995 f8411a44519b7ad668ee1c9d817e91b6 546 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS06995 f8411a44519b7ad668ee1c9d817e91b6 546 Pfam PF00501 AMP-binding enzyme 29 438 1.8E-111 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS06995 f8411a44519b7ad668ee1c9d817e91b6 546 SUPERFAMILY SSF56801 13 538 1.57E-160 T 06-07-2017 SMD11_RS06995 f8411a44519b7ad668ee1c9d817e91b6 546 Gene3D G3DSA:2.30.38.10 354 429 7.6E-31 T 06-07-2017 SMD11_RS06995 f8411a44519b7ad668ee1c9d817e91b6 546 Gene3D G3DSA:3.30.300.30 435 539 5.6E-33 T 06-07-2017 SMD11_RS06995 f8411a44519b7ad668ee1c9d817e91b6 546 Gene3D G3DSA:3.40.50.980 202 347 4.4E-51 T 06-07-2017 SMD11_RS06995 f8411a44519b7ad668ee1c9d817e91b6 546 Pfam PF13193 AMP-binding enzyme C-terminal domain 447 523 8.5E-19 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS06995 f8411a44519b7ad668ee1c9d817e91b6 546 Gene3D G3DSA:3.40.50.980 25 201 4.0E-37 T 06-07-2017 SMD11_RS04460 bcd51fd1d336fa89e95851c85f654699 328 SMART SM00825 Beta-ketoacyl synthase 81 325 2.0E-22 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS04460 bcd51fd1d336fa89e95851c85f654699 328 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 242 258 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS04460 bcd51fd1d336fa89e95851c85f654699 328 Gene3D G3DSA:3.40.47.10 78 327 3.2E-83 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS04460 bcd51fd1d336fa89e95851c85f654699 328 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 79 328 2.6E-80 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS04460 bcd51fd1d336fa89e95851c85f654699 328 SUPERFAMILY SSF53901 80 328 6.56E-74 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS04460 bcd51fd1d336fa89e95851c85f654699 328 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 247 265 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 SMD11_RS31535 379eb80c8eaa2c814e8ed49d9b830ae9 199 Pfam PF03358 NADPH-dependent FMN reductase 56 141 3.1E-9 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMD11_RS31535 379eb80c8eaa2c814e8ed49d9b830ae9 199 Gene3D G3DSA:3.40.50.360 55 167 3.5E-12 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS31535 379eb80c8eaa2c814e8ed49d9b830ae9 199 SUPERFAMILY SSF52218 57 160 6.1E-11 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS08895 92fe9b1decbebf0375314d9e093d999d 332 Gene3D G3DSA:3.40.190.10 264 327 2.0E-27 T 06-07-2017 SMD11_RS08895 92fe9b1decbebf0375314d9e093d999d 332 Gene3D G3DSA:3.40.190.10 43 122 2.0E-27 T 06-07-2017 SMD11_RS08895 92fe9b1decbebf0375314d9e093d999d 332 Pfam PF16868 NMT1-like family 46 327 7.4E-46 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family SMD11_RS08895 92fe9b1decbebf0375314d9e093d999d 332 SUPERFAMILY SSF53850 42 327 3.91E-52 T 06-07-2017 SMD11_RS08895 92fe9b1decbebf0375314d9e093d999d 332 Gene3D G3DSA:3.40.190.10 126 263 2.4E-30 T 06-07-2017 SMD11_RS08895 92fe9b1decbebf0375314d9e093d999d 332 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 19 329 8.7E-72 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family SMD11_RS21430 52ef7e75f0cebe5d137429f19aaf6a83 210 Pfam PF13460 NAD(P)H-binding 7 197 2.4E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS21430 52ef7e75f0cebe5d137429f19aaf6a83 210 SUPERFAMILY SSF51735 1 207 1.09E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS21430 52ef7e75f0cebe5d137429f19aaf6a83 210 Gene3D G3DSA:3.40.50.720 1 207 1.1E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS16175 b0ca00519ef56ae31c582f1a9c2a604b 168 Pfam PF02627 Carboxymuconolactone decarboxylase family 25 106 2.7E-10 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS16175 b0ca00519ef56ae31c582f1a9c2a604b 168 SUPERFAMILY SSF69118 22 160 4.46E-28 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS16175 b0ca00519ef56ae31c582f1a9c2a604b 168 Gene3D G3DSA:1.20.1290.10 22 158 1.7E-31 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS13285 63f3e7ce1dfa0f94dfdeeb4d408c3441 515 SUPERFAMILY SSF51261 371 507 2.2E-41 T 06-07-2017 IPR011055 Duplicated hybrid motif SMD11_RS13285 63f3e7ce1dfa0f94dfdeeb4d408c3441 515 Pfam PF01551 Peptidase family M23 411 503 1.4E-27 T 06-07-2017 IPR016047 Peptidase M23 SMD11_RS13285 63f3e7ce1dfa0f94dfdeeb4d408c3441 515 Gene3D G3DSA:2.70.70.10 365 508 1.5E-41 T 06-07-2017 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 Gene3D G3DSA:3.30.390.30 329 453 2.0E-30 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 SUPERFAMILY SSF51905 2 331 1.8E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 PIRSF PIRSF000350 1 454 5.9E-77 T 06-07-2017 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 321 1.4E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 Gene3D G3DSA:3.50.50.60 4 145 1.4E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 260 274 2.6E-53 T 06-07-2017 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.6E-53 T 06-07-2017 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 148 2.6E-53 T 06-07-2017 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 2.6E-53 T 06-07-2017 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 358 2.6E-53 T 06-07-2017 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 425 445 2.6E-53 T 06-07-2017 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 418 2.6E-53 T 06-07-2017 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 175 200 2.6E-53 T 06-07-2017 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.6E-53 T 06-07-2017 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 SUPERFAMILY SSF55424 337 452 2.58E-28 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 Gene3D G3DSA:3.50.50.60 146 328 1.2E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 342 448 3.6E-25 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 4.2E-20 T 06-07-2017 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 175 193 4.2E-20 T 06-07-2017 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 275 4.2E-20 T 06-07-2017 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.2E-20 T 06-07-2017 SMD11_RS28665 88fb74d6a98557cded2eb42ac62d2668 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 4.2E-20 T 06-07-2017 SMD11_RS24925 67bf8912c525e92810d77f0b636c9c67 609 Pfam PF02653 Branched-chain amino acid transport system / permease component 277 567 1.8E-45 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD11_RS15605 2c63f0f5aa52492571762f23e73afc4a 190 SUPERFAMILY SSF88946 32 103 8.63E-15 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS15605 2c63f0f5aa52492571762f23e73afc4a 190 SUPERFAMILY SSF88659 113 187 2.99E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS15605 2c63f0f5aa52492571762f23e73afc4a 190 Pfam PF04542 Sigma-70 region 2 38 102 5.2E-11 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS15605 2c63f0f5aa52492571762f23e73afc4a 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 185 1.3E-21 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS15605 2c63f0f5aa52492571762f23e73afc4a 190 Gene3D G3DSA:1.10.1740.10 32 102 6.1E-15 T 06-07-2017 SMD11_RS15605 2c63f0f5aa52492571762f23e73afc4a 190 Gene3D G3DSA:1.10.10.10 125 187 2.2E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15605 2c63f0f5aa52492571762f23e73afc4a 190 Pfam PF08281 Sigma-70, region 4 129 182 3.5E-12 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS15605 2c63f0f5aa52492571762f23e73afc4a 190 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 29 188 4.2E-56 T 06-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMD11_RS30710 dac67d4961a4ec46dba2f820aab8eb88 451 SUPERFAMILY SSF53187 67 269 7.94E-42 T 06-07-2017 SMD11_RS30710 dac67d4961a4ec46dba2f820aab8eb88 451 Pfam PF00246 Zinc carboxypeptidase 84 189 4.1E-21 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS30710 dac67d4961a4ec46dba2f820aab8eb88 451 Gene3D G3DSA:3.40.630.10 69 341 1.4E-37 T 06-07-2017 SMD11_RS30710 dac67d4961a4ec46dba2f820aab8eb88 451 SMART SM00631 69 287 1.2E-4 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS33120 92baa54e4ad439100097a04dc4ad560b 146 Pfam PF06841 T4-like virus tail tube protein gp19 11 143 2.4E-26 T 06-07-2017 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 SMD11_RS33120 92baa54e4ad439100097a04dc4ad560b 146 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 6 145 3.2E-27 T 06-07-2017 IPR011747 Conserved hypothetical protein CHP02241 SMD11_RS27000 eb538ae0f628f03a0364a492807a9b6f 272 Gene3D G3DSA:3.30.1330.30 7 105 1.0E-17 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like SMD11_RS27000 eb538ae0f628f03a0364a492807a9b6f 272 Gene3D G3DSA:3.40.1280.10 116 266 9.3E-52 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMD11_RS27000 eb538ae0f628f03a0364a492807a9b6f 272 Pfam PF00588 SpoU rRNA Methylase family 121 263 3.7E-33 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SMD11_RS27000 eb538ae0f628f03a0364a492807a9b6f 272 SUPERFAMILY SSF75217 101 267 9.81E-39 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases SMD11_RS27000 eb538ae0f628f03a0364a492807a9b6f 272 SUPERFAMILY SSF55315 6 106 3.3E-18 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like SMD11_RS15685 8ce72f5d0b3e6b13949615f15b394674 339 SMART SM00331 99 320 6.7E-29 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS15685 8ce72f5d0b3e6b13949615f15b394674 339 SUPERFAMILY SSF81606 115 320 1.44E-10 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS15685 8ce72f5d0b3e6b13949615f15b394674 339 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 127 320 1.1E-38 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS18930 bd986c401a4863703f26069d6db0da8d 93 PRINTS PR00973 Ribosomal protein S17 family signature 34 57 2.8E-11 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18930 bd986c401a4863703f26069d6db0da8d 93 PRINTS PR00973 Ribosomal protein S17 family signature 76 83 2.8E-11 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18930 bd986c401a4863703f26069d6db0da8d 93 PRINTS PR00973 Ribosomal protein S17 family signature 66 76 2.8E-11 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18930 bd986c401a4863703f26069d6db0da8d 93 Gene3D G3DSA:2.40.50.140 15 92 4.5E-34 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS18930 bd986c401a4863703f26069d6db0da8d 93 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 15 86 1.6E-34 T 06-07-2017 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18930 bd986c401a4863703f26069d6db0da8d 93 ProSitePatterns PS00056 Ribosomal protein S17 signature. 66 78 - T 06-07-2017 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18930 bd986c401a4863703f26069d6db0da8d 93 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 13 91 25.17 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18930 bd986c401a4863703f26069d6db0da8d 93 SUPERFAMILY SSF50249 15 92 1.07E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS18930 bd986c401a4863703f26069d6db0da8d 93 Pfam PF00366 Ribosomal protein S17 20 87 3.7E-30 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18930 bd986c401a4863703f26069d6db0da8d 93 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 20 86 3.0E-31 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS31935 60f3c2ea8286b9b935617a02bd0a8895 404 Pfam PF07690 Major Facilitator Superfamily 18 322 4.5E-12 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS31935 60f3c2ea8286b9b935617a02bd0a8895 404 Gene3D G3DSA:1.20.1250.20 221 384 2.4E-7 T 06-07-2017 SMD11_RS31935 60f3c2ea8286b9b935617a02bd0a8895 404 SUPERFAMILY SSF103473 15 388 5.75E-23 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS31935 60f3c2ea8286b9b935617a02bd0a8895 404 Gene3D G3DSA:1.20.1250.20 13 189 1.7E-7 T 06-07-2017 SMD11_RS34060 6af8bbf2bcd8f8e77632c8417ce1892b 377 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 359 1.6E-120 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD11_RS34060 6af8bbf2bcd8f8e77632c8417ce1892b 377 SUPERFAMILY SSF56014 276 358 4.51E-13 T 06-07-2017 SMD11_RS34060 6af8bbf2bcd8f8e77632c8417ce1892b 377 Gene3D G3DSA:3.20.20.70 48 172 1.4E-4 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS34060 6af8bbf2bcd8f8e77632c8417ce1892b 377 PIRSF PIRSF004640 11 367 5.2E-138 T 06-07-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD11_RS34060 6af8bbf2bcd8f8e77632c8417ce1892b 377 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.399 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD11_RS34060 6af8bbf2bcd8f8e77632c8417ce1892b 377 Pfam PF04551 GcpE protein 21 361 5.2E-129 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 SMD11_RS34060 6af8bbf2bcd8f8e77632c8417ce1892b 377 SUPERFAMILY SSF51717 47 218 9.42E-8 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS16735 0fc736011240604f5501a48d07f3fc0b 220 PRINTS PR01576 Peptide deformylase signature 130 141 1.9E-32 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS16735 0fc736011240604f5501a48d07f3fc0b 220 PRINTS PR01576 Peptide deformylase signature 161 190 1.9E-32 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS16735 0fc736011240604f5501a48d07f3fc0b 220 PRINTS PR01576 Peptide deformylase signature 68 97 1.9E-32 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS16735 0fc736011240604f5501a48d07f3fc0b 220 PRINTS PR01576 Peptide deformylase signature 142 160 1.9E-32 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS16735 0fc736011240604f5501a48d07f3fc0b 220 SUPERFAMILY SSF56420 31 200 5.23E-51 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS16735 0fc736011240604f5501a48d07f3fc0b 220 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 40 199 1.1E-32 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS16735 0fc736011240604f5501a48d07f3fc0b 220 Hamap MF_00163 Peptide deformylase [def]. 36 203 27.411 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS16735 0fc736011240604f5501a48d07f3fc0b 220 Pfam PF01327 Polypeptide deformylase 38 193 3.4E-44 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS16735 0fc736011240604f5501a48d07f3fc0b 220 Gene3D G3DSA:3.90.45.10 39 206 5.3E-54 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS21310 ff867fb69950e966728d0ccad093fff3 100 Pfam PF00166 Chaperonin 10 Kd subunit 1 84 9.9E-18 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD11_RS21310 ff867fb69950e966728d0ccad093fff3 100 SMART SM00883 1 85 9.7E-20 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD11_RS21310 ff867fb69950e966728d0ccad093fff3 100 Gene3D G3DSA:2.30.33.40 1 84 2.9E-18 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SMD11_RS21310 ff867fb69950e966728d0ccad093fff3 100 SUPERFAMILY SSF50129 2 85 1.95E-16 T 06-07-2017 IPR011032 GroES-like SMD11_RS26020 e2ff5e7e0f4e0bacc5e33555b045d2cd 594 Gene3D G3DSA:3.40.190.10 252 368 8.0E-16 T 06-07-2017 SMD11_RS26020 e2ff5e7e0f4e0bacc5e33555b045d2cd 594 SUPERFAMILY SSF53850 70 584 4.16E-80 T 06-07-2017 SMD11_RS26020 e2ff5e7e0f4e0bacc5e33555b045d2cd 594 Gene3D G3DSA:3.90.76.10 86 251 6.7E-25 T 06-07-2017 SMD11_RS26020 e2ff5e7e0f4e0bacc5e33555b045d2cd 594 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 119 506 1.7E-58 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain SMD11_RS26020 e2ff5e7e0f4e0bacc5e33555b045d2cd 594 Gene3D G3DSA:3.10.105.10 369 561 2.0E-29 T 06-07-2017 SMD11_RS26020 e2ff5e7e0f4e0bacc5e33555b045d2cd 594 PIRSF PIRSF002741 17 594 2.2E-50 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD11_RS25425 c8a69c4edb6147b63975a4db8d94709d 295 Pfam PF04228 Putative neutral zinc metallopeptidase 11 294 5.8E-83 T 06-07-2017 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative SMD11_RS25425 c8a69c4edb6147b63975a4db8d94709d 295 SUPERFAMILY SSF55486 90 220 9.33E-6 T 06-07-2017 SMD11_RS25425 c8a69c4edb6147b63975a4db8d94709d 295 SUPERFAMILY SSF55486 264 282 9.33E-6 T 06-07-2017 SMD11_RS15130 e27e24c34db8b0509d24a369b8ee3ea1 242 PRINTS PR01399 Enterobactin synthetase component D signature 69 87 1.3E-24 T 06-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 SMD11_RS15130 e27e24c34db8b0509d24a369b8ee3ea1 242 PRINTS PR01399 Enterobactin synthetase component D signature 146 162 1.3E-24 T 06-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 SMD11_RS15130 e27e24c34db8b0509d24a369b8ee3ea1 242 PRINTS PR01399 Enterobactin synthetase component D signature 39 59 1.3E-24 T 06-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 SMD11_RS15130 e27e24c34db8b0509d24a369b8ee3ea1 242 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 103 178 3.1E-9 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS15130 e27e24c34db8b0509d24a369b8ee3ea1 242 SUPERFAMILY SSF56214 103 219 2.35E-15 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS15130 e27e24c34db8b0509d24a369b8ee3ea1 242 Gene3D G3DSA:3.90.470.20 116 178 1.1E-5 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS18705 861687d3370892e2f292a48d01fc7a28 190 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 3 157 24.126 T 06-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18705 861687d3370892e2f292a48d01fc7a28 190 Gene3D G3DSA:3.30.70.20 47 133 4.5E-16 T 06-07-2017 SMD11_RS18705 861687d3370892e2f292a48d01fc7a28 190 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD11_RS18705 861687d3370892e2f292a48d01fc7a28 190 Pfam PF00037 4Fe-4S binding domain 95 115 7.7E-9 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD11_RS18705 861687d3370892e2f292a48d01fc7a28 190 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD11_RS18705 861687d3370892e2f292a48d01fc7a28 190 SUPERFAMILY SSF54862 36 143 3.56E-19 T 06-07-2017 SMD11_RS24240 db39ec9bb8a9e9b38c82200945dc4831 452 Gene3D G3DSA:3.90.1150.10 296 433 1.1E-15 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS24240 db39ec9bb8a9e9b38c82200945dc4831 452 Pfam PF00266 Aminotransferase class-V 38 426 3.1E-75 T 06-07-2017 IPR000192 Aminotransferase class V domain SMD11_RS24240 db39ec9bb8a9e9b38c82200945dc4831 452 SUPERFAMILY SSF53383 35 435 7.43E-83 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS24240 db39ec9bb8a9e9b38c82200945dc4831 452 Gene3D G3DSA:3.40.640.10 54 295 1.8E-66 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS24320 72b6da7b5bed412dcfe241af647faf77 253 SUPERFAMILY SSF56219 18 251 5.5E-25 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS24320 72b6da7b5bed412dcfe241af647faf77 253 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 25 241 2.7E-12 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS24320 72b6da7b5bed412dcfe241af647faf77 253 Gene3D G3DSA:3.60.10.10 22 172 5.3E-7 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS14125 d6d9f4fb06dbccb533619abb39250741 464 SUPERFAMILY SSF47323 318 462 3.01E-30 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS14125 d6d9f4fb06dbccb533619abb39250741 464 Pfam PF09190 DALR domain 340 393 7.3E-10 T 06-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 SMD11_RS14125 d6d9f4fb06dbccb533619abb39250741 464 SMART SM00840 340 401 3.9E-16 T 06-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 SMD11_RS14125 d6d9f4fb06dbccb533619abb39250741 464 Gene3D G3DSA:3.40.50.620 22 303 7.2E-94 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS14125 d6d9f4fb06dbccb533619abb39250741 464 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 462 2.6E-136 T 06-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 SMD11_RS14125 d6d9f4fb06dbccb533619abb39250741 464 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 18 311 8.1E-117 T 06-07-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 SMD11_RS14125 d6d9f4fb06dbccb533619abb39250741 464 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 464 35.229 T 06-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 SMD11_RS14125 d6d9f4fb06dbccb533619abb39250741 464 Gene3D G3DSA:1.20.120.640 304 392 2.1E-19 T 06-07-2017 SMD11_RS14125 d6d9f4fb06dbccb533619abb39250741 464 SUPERFAMILY SSF52374 4 310 5.9E-86 T 06-07-2017 SMD11_RS14125 d6d9f4fb06dbccb533619abb39250741 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.3E-27 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD11_RS14125 d6d9f4fb06dbccb533619abb39250741 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 2.3E-27 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD11_RS14125 d6d9f4fb06dbccb533619abb39250741 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 190 208 2.3E-27 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD11_RS14125 d6d9f4fb06dbccb533619abb39250741 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 221 242 2.3E-27 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SMD11_RS32875 87e7c35f57680dd4d17ea228f6b69d5b 256 SUPERFAMILY SSF54637 106 240 2.94E-14 T 06-07-2017 IPR029069 HotDog domain SMD11_RS32875 87e7c35f57680dd4d17ea228f6b69d5b 256 Gene3D G3DSA:3.10.129.10 106 245 7.0E-15 T 06-07-2017 IPR029069 HotDog domain SMD11_RS09715 d8a99910f0fb268977138b7db9434974 169 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 12 167 34.579 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 SMD11_RS09715 d8a99910f0fb268977138b7db9434974 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 30 51 4.8E-49 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 SMD11_RS09715 d8a99910f0fb268977138b7db9434974 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 121 143 4.8E-49 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 SMD11_RS09715 d8a99910f0fb268977138b7db9434974 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 59 83 4.8E-49 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 SMD11_RS09715 d8a99910f0fb268977138b7db9434974 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 95 111 4.8E-49 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 SMD11_RS09715 d8a99910f0fb268977138b7db9434974 169 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 12 30 4.8E-49 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 SMD11_RS09715 d8a99910f0fb268977138b7db9434974 169 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 13 165 2.1E-58 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 SMD11_RS09715 d8a99910f0fb268977138b7db9434974 169 Pfam PF01467 Cytidylyltransferase-like 16 142 4.4E-17 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SMD11_RS09715 d8a99910f0fb268977138b7db9434974 169 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 13 69 3.2E-15 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SMD11_RS09715 d8a99910f0fb268977138b7db9434974 169 Gene3D G3DSA:3.40.50.620 12 165 4.9E-51 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS09715 d8a99910f0fb268977138b7db9434974 169 SUPERFAMILY SSF52374 12 165 1.46E-44 T 06-07-2017 SMD11_RS09715 d8a99910f0fb268977138b7db9434974 169 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 21 131 0.003 T 06-07-2017 SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 Gene3D G3DSA:1.25.40.10 775 1006 3.8E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 Gene3D G3DSA:1.25.40.10 233 294 3.8E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 SMART SM01043 162 306 1.1E-51 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 Gene3D G3DSA:1.10.10.10 88 156 7.0E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 Pfam PF03704 Bacterial transcriptional activator domain 162 306 5.0E-44 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 PRINTS PR00364 Disease resistance protein signature 363 378 1.4E-8 T 06-07-2017 SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 PRINTS PR00364 Disease resistance protein signature 525 539 1.4E-8 T 06-07-2017 SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 PRINTS PR00364 Disease resistance protein signature 440 454 1.4E-8 T 06-07-2017 SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 SUPERFAMILY SSF52540 331 591 9.53E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 SUPERFAMILY SSF48452 157 326 1.68E-35 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 SUPERFAMILY SSF48452 834 1012 6.96E-17 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 SUPERFAMILY SSF46894 71 144 3.12E-11 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 SMART SM00862 80 155 3.9E-7 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 Pfam PF13424 Tetratricopeptide repeat 818 889 3.1E-10 T 06-07-2017 SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 Pfam PF00486 Transcriptional regulatory protein, C terminal 88 143 1.4E-7 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS02465 53ca0260d86bed44f4bd777196deb68e 1028 Pfam PF00931 NB-ARC domain 362 546 1.1E-8 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 SMD11_RS23970 b634b813b1415a934e834f48b9263e74 230 SMART SM00382 32 220 5.5E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS23970 b634b813b1415a934e834f48b9263e74 230 Gene3D G3DSA:3.40.50.300 7 221 2.3E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23970 b634b813b1415a934e834f48b9263e74 230 Pfam PF00005 ABC transporter 23 171 1.7E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS23970 b634b813b1415a934e834f48b9263e74 230 SUPERFAMILY SSF52540 8 225 1.06E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03790 2f9388dfefcb41163f62d998b2797989 250 SUPERFAMILY SSF100950 3 247 2.43E-51 T 06-07-2017 SMD11_RS03790 2f9388dfefcb41163f62d998b2797989 250 SMART SM00882 7 209 0.001 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 SMD11_RS03790 2f9388dfefcb41163f62d998b2797989 250 Gene3D G3DSA:3.40.810.20 3 247 1.3E-66 T 06-07-2017 SMD11_RS18485 392719351fca0b04c1cd4b455e1a55b5 283 Pfam PF02621 Menaquinone biosynthesis 10 266 3.5E-70 T 06-07-2017 IPR003773 Menaquinone biosynthesis enzyme SMD11_RS18485 392719351fca0b04c1cd4b455e1a55b5 283 Hamap MF_00995 Chorismate dehydratase [mqnA]. 10 272 31.376 T 06-07-2017 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 SMD11_RS18485 392719351fca0b04c1cd4b455e1a55b5 283 Gene3D G3DSA:3.40.190.10 6 82 1.8E-67 T 06-07-2017 SMD11_RS18485 392719351fca0b04c1cd4b455e1a55b5 283 Gene3D G3DSA:3.40.190.10 185 282 1.8E-67 T 06-07-2017 SMD11_RS18485 392719351fca0b04c1cd4b455e1a55b5 283 SUPERFAMILY SSF53850 9 265 1.49E-74 T 06-07-2017 SMD11_RS18485 392719351fca0b04c1cd4b455e1a55b5 283 Gene3D G3DSA:3.40.190.10 83 184 3.1E-36 T 06-07-2017 SMD11_RS29965 9f56aa1be45586aac6a842b70c42caa8 663 Pfam PF00733 Asparagine synthase 241 608 9.0E-74 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMD11_RS29965 9f56aa1be45586aac6a842b70c42caa8 663 SUPERFAMILY SSF52402 477 601 1.33E-58 T 06-07-2017 SMD11_RS29965 9f56aa1be45586aac6a842b70c42caa8 663 SUPERFAMILY SSF52402 228 382 1.33E-58 T 06-07-2017 SMD11_RS29965 9f56aa1be45586aac6a842b70c42caa8 663 Gene3D G3DSA:3.60.20.10 22 225 6.0E-71 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS29965 9f56aa1be45586aac6a842b70c42caa8 663 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 557 3.2E-135 T 06-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SMD11_RS29965 9f56aa1be45586aac6a842b70c42caa8 663 PIRSF PIRSF001589 1 646 7.6E-149 T 06-07-2017 SMD11_RS29965 9f56aa1be45586aac6a842b70c42caa8 663 Gene3D G3DSA:3.40.50.620 228 386 1.2E-66 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS29965 9f56aa1be45586aac6a842b70c42caa8 663 Gene3D G3DSA:3.40.50.620 477 601 1.2E-66 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS29965 9f56aa1be45586aac6a842b70c42caa8 663 SUPERFAMILY SSF56235 1 223 6.26E-61 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS29965 9f56aa1be45586aac6a842b70c42caa8 663 Pfam PF13537 Glutamine amidotransferase domain 49 167 1.6E-43 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain SMD11_RS08740 a3fbc1512bf73762f4da410f0e52bbc3 721 Gene3D G3DSA:1.10.10.10 444 501 1.7E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08740 a3fbc1512bf73762f4da410f0e52bbc3 721 Gene3D G3DSA:3.40.50.300 16 206 6.3E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08740 a3fbc1512bf73762f4da410f0e52bbc3 721 SUPERFAMILY SSF52540 35 355 2.63E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08740 a3fbc1512bf73762f4da410f0e52bbc3 721 SUPERFAMILY SSF53271 679 718 1.84E-10 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS08740 a3fbc1512bf73762f4da410f0e52bbc3 721 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 23 362 4.0E-68 T 06-07-2017 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 SMD11_RS08740 a3fbc1512bf73762f4da410f0e52bbc3 721 Pfam PF00271 Helicase conserved C-terminal domain 254 345 8.4E-13 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS08740 a3fbc1512bf73762f4da410f0e52bbc3 721 Pfam PF16124 RecQ zinc-binding 446 488 2.6E-6 T 06-07-2017 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain SMD11_RS08740 a3fbc1512bf73762f4da410f0e52bbc3 721 SMART SM00490 265 346 8.7E-22 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS08740 a3fbc1512bf73762f4da410f0e52bbc3 721 Pfam PF00270 DEAD/DEAH box helicase 30 196 8.4E-16 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD11_RS08740 a3fbc1512bf73762f4da410f0e52bbc3 721 Gene3D G3DSA:3.40.50.2020 649 718 2.8E-9 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS08740 a3fbc1512bf73762f4da410f0e52bbc3 721 Gene3D G3DSA:3.40.50.300 220 368 2.7E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08740 a3fbc1512bf73762f4da410f0e52bbc3 721 SMART SM00487 23 231 7.5E-22 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS23720 f3024b920b1d42afb4b102b951f6376c 257 Pfam PF02274 Amidinotransferase 21 256 6.3E-14 T 06-07-2017 SMD11_RS23720 f3024b920b1d42afb4b102b951f6376c 257 SUPERFAMILY SSF55909 1 257 2.5E-53 T 06-07-2017 SMD11_RS23720 f3024b920b1d42afb4b102b951f6376c 257 Gene3D G3DSA:3.75.10.10 1 256 7.3E-59 T 06-07-2017 SMD11_RS08460 9d98898040d8b60d562d4dd75b6c4e04 222 Gene3D G3DSA:3.40.50.720 1 140 2.2E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08460 9d98898040d8b60d562d4dd75b6c4e04 222 SUPERFAMILY SSF51735 1 140 1.97E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08460 9d98898040d8b60d562d4dd75b6c4e04 222 Pfam PF02254 TrkA-N domain 3 116 7.5E-26 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SMD11_RS08460 9d98898040d8b60d562d4dd75b6c4e04 222 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.1E-8 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS08460 9d98898040d8b60d562d4dd75b6c4e04 222 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.1E-8 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS08460 9d98898040d8b60d562d4dd75b6c4e04 222 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.1E-8 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS08460 9d98898040d8b60d562d4dd75b6c4e04 222 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.1E-8 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS08460 9d98898040d8b60d562d4dd75b6c4e04 222 Pfam PF02080 TrkA-C domain 149 213 8.0E-12 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD11_RS08460 9d98898040d8b60d562d4dd75b6c4e04 222 Gene3D G3DSA:3.30.70.1450 149 212 2.1E-5 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD11_RS08460 9d98898040d8b60d562d4dd75b6c4e04 222 SUPERFAMILY SSF116726 141 211 5.89E-8 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SMD11_RS26320 d24da9de03b9e358cfcad9cb143190d3 77 Pfam PF03777 Small secreted domain (DUF320) 21 76 1.3E-27 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD11_RS04760 4c3c11227f4112dc18b48168253c7dac 152 Gene3D G3DSA:3.10.180.10 20 150 1.5E-32 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS04760 4c3c11227f4112dc18b48168253c7dac 152 SUPERFAMILY SSF54593 18 150 6.18E-28 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS04760 4c3c11227f4112dc18b48168253c7dac 152 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 19 146 7.1E-15 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS15270 3593a7dcc022597ca81641375660093c 1218 SUPERFAMILY SSF103473 38 465 8.37E-11 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS15270 3593a7dcc022597ca81641375660093c 1218 Hamap MF_00165 Thymidylate kinase [tmk]. 509 708 30.658 T 06-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SMD11_RS15270 3593a7dcc022597ca81641375660093c 1218 SUPERFAMILY SSF52540 507 709 1.03E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15270 3593a7dcc022597ca81641375660093c 1218 Pfam PF02223 Thymidylate kinase 513 697 2.2E-46 T 06-07-2017 SMD11_RS15270 3593a7dcc022597ca81641375660093c 1218 Gene3D G3DSA:3.40.50.300 508 708 6.0E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15270 3593a7dcc022597ca81641375660093c 1218 ProSitePatterns PS01331 Thymidylate kinase signature. 598 610 - T 06-07-2017 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SMD11_RS15270 3593a7dcc022597ca81641375660093c 1218 Gene3D G3DSA:1.20.1250.20 293 469 1.3E-12 T 06-07-2017 SMD11_RS15270 3593a7dcc022597ca81641375660093c 1218 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 508 697 5.9E-51 T 06-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SMD11_RS06805 5469368ef5bada5973e14bdef8d506b6 294 Pfam PF00188 Cysteine-rich secretory protein family 178 291 1.3E-16 T 06-07-2017 IPR014044 CAP domain SMD11_RS06805 5469368ef5bada5973e14bdef8d506b6 294 SMART SM00458 5 146 0.0011 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS06805 5469368ef5bada5973e14bdef8d506b6 294 Gene3D G3DSA:2.80.10.50 81 146 8.4E-8 T 06-07-2017 SMD11_RS06805 5469368ef5bada5973e14bdef8d506b6 294 Gene3D G3DSA:2.80.10.50 4 57 8.6E-9 T 06-07-2017 SMD11_RS06805 5469368ef5bada5973e14bdef8d506b6 294 SUPERFAMILY SSF55797 175 288 1.92E-16 T 06-07-2017 IPR014044 CAP domain SMD11_RS06805 5469368ef5bada5973e14bdef8d506b6 294 Gene3D G3DSA:3.40.33.10 175 263 3.3E-8 T 06-07-2017 IPR014044 CAP domain SMD11_RS06805 5469368ef5bada5973e14bdef8d506b6 294 SUPERFAMILY SSF50370 4 146 2.23E-18 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS27330 34fd1d5d782adbdd90951258e12afae2 142 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 2 137 22.119 T 06-07-2017 IPR011605 NusB antitermination factor GO:0006353 SMD11_RS27330 34fd1d5d782adbdd90951258e12afae2 142 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 4 133 6.9E-39 T 06-07-2017 IPR011605 NusB antitermination factor GO:0006353 SMD11_RS27330 34fd1d5d782adbdd90951258e12afae2 142 Gene3D G3DSA:1.10.940.10 2 132 8.0E-43 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMD11_RS27330 34fd1d5d782adbdd90951258e12afae2 142 Pfam PF01029 NusB family 5 132 3.5E-33 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMD11_RS27330 34fd1d5d782adbdd90951258e12afae2 142 SUPERFAMILY SSF48013 4 132 4.97E-39 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMD11_RS29930 d1618b9a3389b93343e06455d0e6fec9 292 SUPERFAMILY SSF51621 5 256 1.57E-59 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS29930 d1618b9a3389b93343e06455d0e6fec9 292 Pfam PF13714 Phosphoenolpyruvate phosphomutase 17 246 1.1E-33 T 06-07-2017 SMD11_RS29930 d1618b9a3389b93343e06455d0e6fec9 292 Gene3D G3DSA:3.20.20.60 5 253 9.9E-57 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS01685 b5518857ca4af32013989abb31bca0c4 273 SUPERFAMILY SSF51735 4 253 6.33E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS01685 b5518857ca4af32013989abb31bca0c4 273 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 201 3.8E-5 T 06-07-2017 SMD11_RS01685 b5518857ca4af32013989abb31bca0c4 273 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 252 1.5E-62 T 06-07-2017 SMD11_RS01685 b5518857ca4af32013989abb31bca0c4 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS01685 b5518857ca4af32013989abb31bca0c4 273 Gene3D G3DSA:3.40.50.720 4 254 3.4E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS01685 b5518857ca4af32013989abb31bca0c4 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.8E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01685 b5518857ca4af32013989abb31bca0c4 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.8E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01685 b5518857ca4af32013989abb31bca0c4 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.8E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01685 b5518857ca4af32013989abb31bca0c4 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.8E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01685 b5518857ca4af32013989abb31bca0c4 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.8E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01685 b5518857ca4af32013989abb31bca0c4 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.8E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01685 b5518857ca4af32013989abb31bca0c4 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 8.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01685 b5518857ca4af32013989abb31bca0c4 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 8.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01685 b5518857ca4af32013989abb31bca0c4 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 8.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30720 28895fb66b76f8e91d7d71c7e47a0d7a 474 Gene3D G3DSA:3.50.50.60 2 154 1.5E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS30720 28895fb66b76f8e91d7d71c7e47a0d7a 474 Gene3D G3DSA:3.50.50.60 266 305 1.5E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS30720 28895fb66b76f8e91d7d71c7e47a0d7a 474 SUPERFAMILY SSF51905 255 344 2.11E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS30720 28895fb66b76f8e91d7d71c7e47a0d7a 474 SUPERFAMILY SSF51905 2 164 2.11E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS30720 28895fb66b76f8e91d7d71c7e47a0d7a 474 Gene3D G3DSA:3.30.9.10 155 261 1.6E-10 T 06-07-2017 SMD11_RS30720 28895fb66b76f8e91d7d71c7e47a0d7a 474 Gene3D G3DSA:3.30.9.10 316 336 1.6E-10 T 06-07-2017 SMD11_RS30720 28895fb66b76f8e91d7d71c7e47a0d7a 474 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 268 283 7.6E-48 T 06-07-2017 SMD11_RS30720 28895fb66b76f8e91d7d71c7e47a0d7a 474 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 319 335 7.6E-48 T 06-07-2017 SMD11_RS30720 28895fb66b76f8e91d7d71c7e47a0d7a 474 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 143 158 7.6E-48 T 06-07-2017 SMD11_RS30720 28895fb66b76f8e91d7d71c7e47a0d7a 474 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 299 7.6E-48 T 06-07-2017 SMD11_RS30720 28895fb66b76f8e91d7d71c7e47a0d7a 474 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 7.6E-48 T 06-07-2017 SMD11_RS30720 28895fb66b76f8e91d7d71c7e47a0d7a 474 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 319 7.6E-48 T 06-07-2017 SMD11_RS30720 28895fb66b76f8e91d7d71c7e47a0d7a 474 Pfam PF01494 FAD binding domain 2 333 3.1E-91 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 Gene3D G3DSA:3.30.70.380 743 834 7.0E-30 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 Gene3D G3DSA:3.50.40.10 208 408 6.3E-84 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 828 39.702 T 06-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 Gene3D G3DSA:2.40.50.140 46 162 7.4E-39 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 Pfam PF03483 B3/4 domain 221 399 4.2E-68 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 Pfam PF03147 Ferredoxin-fold anticodon binding domain 741 834 6.9E-24 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 SMART SM00896 741 834 6.6E-41 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 Pfam PF03484 tRNA synthetase B5 domain 417 482 2.6E-17 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 SUPERFAMILY SSF50249 45 205 1.51E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 SMART SM00874 415 482 2.7E-21 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 Pfam PF01588 Putative tRNA binding domain 48 155 6.8E-21 T 06-07-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 SUPERFAMILY SSF55681 478 594 4.92E-41 T 06-07-2017 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 SUPERFAMILY SSF55681 624 727 4.92E-41 T 06-07-2017 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 Gene3D G3DSA:3.30.930.10 497 727 3.4E-61 T 06-07-2017 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 SUPERFAMILY SSF54991 738 834 1.09E-25 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 Gene3D G3DSA:3.30.56.10 1 40 1.0E-17 T 06-07-2017 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 Gene3D G3DSA:3.30.56.10 164 193 1.0E-17 T 06-07-2017 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 SUPERFAMILY SSF46955 415 486 2.56E-15 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 Gene3D G3DSA:3.30.56.20 415 486 1.8E-22 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 SUPERFAMILY SSF56037 205 407 8.89E-67 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 SMART SM00873 221 399 3.0E-84 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SMD11_RS26735 26789c39e1be9cb28f8cc76b57576e3a 836 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 834 3.1E-185 T 06-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SMD11_RS26265 5e12aded4567cda4f3aa8c1092e09704 311 SUPERFAMILY SSF56281 18 262 4.06E-55 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS26265 5e12aded4567cda4f3aa8c1092e09704 311 Gene3D G3DSA:3.60.15.10 14 238 8.0E-51 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS26265 5e12aded4567cda4f3aa8c1092e09704 311 Pfam PF00753 Metallo-beta-lactamase superfamily 33 215 8.5E-24 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS26265 5e12aded4567cda4f3aa8c1092e09704 311 SMART SM00849 36 215 4.5E-28 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS08780 465281bf8e7c0fc53f95339076f92e41 201 SUPERFAMILY SSF54909 105 170 4.47E-5 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS08780 465281bf8e7c0fc53f95339076f92e41 201 Pfam PF16291 Domain of unknown function (DUF4937 2 86 7.2E-30 T 06-07-2017 IPR032555 Domain of unknown function DUF4937 SMD11_RS06275 d4defdc187376353401e273caabd641c 318 Pfam PF00296 Luciferase-like monooxygenase 5 291 1.0E-52 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS06275 d4defdc187376353401e273caabd641c 318 Gene3D G3DSA:3.20.20.30 2 316 5.2E-68 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS06275 d4defdc187376353401e273caabd641c 318 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 317 1.7E-146 T 06-07-2017 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related SMD11_RS06275 d4defdc187376353401e273caabd641c 318 SUPERFAMILY SSF51679 2 316 2.62E-64 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS11425 600d2643e6389464a027ca1eb79bef00 107 Pfam PF00893 Small Multidrug Resistance protein 1 93 9.9E-25 T 06-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 SMD11_RS11425 600d2643e6389464a027ca1eb79bef00 107 SUPERFAMILY SSF103481 6 105 2.35E-17 T 06-07-2017 SMD11_RS30455 a856ce09829ad010394862b4fa92b27f 140 Gene3D G3DSA:2.40.40.10 40 139 1.5E-11 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain SMD11_RS30455 a856ce09829ad010394862b4fa92b27f 140 SUPERFAMILY SSF50685 27 139 4.88E-20 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain SMD11_RS30455 a856ce09829ad010394862b4fa92b27f 140 Pfam PF03330 Lytic transglycolase 39 132 4.6E-11 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain SMD11_RS31760 9a94cdd1fa3d86a60f07a78e7ba1d801 353 SUPERFAMILY SSF69304 59 93 1.57E-33 T 06-07-2017 SMD11_RS31760 9a94cdd1fa3d86a60f07a78e7ba1d801 353 SUPERFAMILY SSF69304 130 349 1.57E-33 T 06-07-2017 SMD11_RS31760 9a94cdd1fa3d86a60f07a78e7ba1d801 353 Pfam PF07676 WD40-like Beta Propeller Repeat 162 176 2.5E-4 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS31760 9a94cdd1fa3d86a60f07a78e7ba1d801 353 Pfam PF07676 WD40-like Beta Propeller Repeat 258 296 9.4E-10 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS31760 9a94cdd1fa3d86a60f07a78e7ba1d801 353 Pfam PF07676 WD40-like Beta Propeller Repeat 305 330 1.3E-7 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS31760 9a94cdd1fa3d86a60f07a78e7ba1d801 353 Pfam PF07676 WD40-like Beta Propeller Repeat 60 79 2.0E-4 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS31760 9a94cdd1fa3d86a60f07a78e7ba1d801 353 Pfam PF07676 WD40-like Beta Propeller Repeat 211 241 0.032 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS31760 9a94cdd1fa3d86a60f07a78e7ba1d801 353 Gene3D G3DSA:2.130.10.10 59 174 3.7E-17 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS31760 9a94cdd1fa3d86a60f07a78e7ba1d801 353 Gene3D G3DSA:2.120.10.30 175 345 1.9E-38 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 Gene3D G3DSA:3.30.450.20 26 131 1.1E-20 T 06-07-2017 SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 SUPERFAMILY SSF81606 487 686 1.75E-13 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 SUPERFAMILY SSF55781 353 458 1.46E-18 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 505 686 2.7E-50 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 Pfam PF08448 PAS fold 149 262 1.5E-20 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 Gene3D G3DSA:3.30.450.20 139 260 4.8E-20 T 06-07-2017 SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 SUPERFAMILY SSF55785 136 258 3.14E-14 T 06-07-2017 IPR000014 PAS domain SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 SMART SM00065 269 457 3.1E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 31 132 2.8E-14 T 06-07-2017 IPR000014 PAS domain SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 147 265 7.9E-6 T 06-07-2017 IPR000014 PAS domain SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 Pfam PF00989 PAS fold 26 131 7.3E-13 T 06-07-2017 IPR013767 PAS fold GO:0006355 SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 Gene3D G3DSA:3.30.450.40 275 455 1.6E-37 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 SMART SM00331 475 686 4.5E-41 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 Pfam PF01590 GAF domain 288 447 3.0E-14 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 SMART SM00091 21 88 1.5E-8 T 06-07-2017 IPR000014 PAS domain SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 SMART SM00091 143 209 0.36 T 06-07-2017 IPR000014 PAS domain SMD11_RS04430 a2c65ee9b486c3d0e137023e8c1d8473 690 SUPERFAMILY SSF55785 26 131 9.95E-21 T 06-07-2017 IPR000014 PAS domain SMD11_RS25625 7db7edd7a745fc86d30549dbceddc5cd 214 Gene3D G3DSA:3.40.50.2300 6 155 6.0E-42 T 06-07-2017 SMD11_RS25625 7db7edd7a745fc86d30549dbceddc5cd 214 SUPERFAMILY SSF46894 150 212 2.93E-23 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS25625 7db7edd7a745fc86d30549dbceddc5cd 214 SUPERFAMILY SSF52172 6 135 6.12E-36 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS25625 7db7edd7a745fc86d30549dbceddc5cd 214 Gene3D G3DSA:1.10.10.10 156 212 1.1E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS25625 7db7edd7a745fc86d30549dbceddc5cd 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.9E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS25625 7db7edd7a745fc86d30549dbceddc5cd 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.9E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS25625 7db7edd7a745fc86d30549dbceddc5cd 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.9E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS25625 7db7edd7a745fc86d30549dbceddc5cd 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS25625 7db7edd7a745fc86d30549dbceddc5cd 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 1.1E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS25625 7db7edd7a745fc86d30549dbceddc5cd 214 SMART SM00448 6 119 1.6E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS25625 7db7edd7a745fc86d30549dbceddc5cd 214 SMART SM00421 150 207 5.2E-28 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS25625 7db7edd7a745fc86d30549dbceddc5cd 214 Pfam PF00072 Response regulator receiver domain 8 119 1.3E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS33570 7d14fdfd5e2c9a4bd6df9a82727c5d99 834 SUPERFAMILY SSF82866 557 797 1.83E-26 T 06-07-2017 SMD11_RS33570 7d14fdfd5e2c9a4bd6df9a82727c5d99 834 Pfam PF03176 MMPL family 120 454 4.9E-47 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 SMD11_RS33570 7d14fdfd5e2c9a4bd6df9a82727c5d99 834 Pfam PF03176 MMPL family 484 798 3.7E-30 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 SMD11_RS33570 7d14fdfd5e2c9a4bd6df9a82727c5d99 834 Gene3D G3DSA:1.20.1640.10 210 411 5.2E-30 T 06-07-2017 SMD11_RS33570 7d14fdfd5e2c9a4bd6df9a82727c5d99 834 Gene3D G3DSA:1.20.1640.10 583 802 1.2E-28 T 06-07-2017 SMD11_RS33570 7d14fdfd5e2c9a4bd6df9a82727c5d99 834 SUPERFAMILY SSF82866 195 411 1.27E-28 T 06-07-2017 SMD11_RS17925 a14b63d10cc9d131bcba4f0cfd20b30c 749 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 24 747 5.8E-264 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD11_RS17925 a14b63d10cc9d131bcba4f0cfd20b30c 749 Pfam PF02769 AIR synthase related protein, C-terminal domain 211 366 2.2E-32 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain SMD11_RS17925 a14b63d10cc9d131bcba4f0cfd20b30c 749 Pfam PF02769 AIR synthase related protein, C-terminal domain 586 722 7.8E-21 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain SMD11_RS17925 a14b63d10cc9d131bcba4f0cfd20b30c 749 PIRSF PIRSF001587 6 749 8.5E-292 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD11_RS17925 a14b63d10cc9d131bcba4f0cfd20b30c 749 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 749 310.448 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD11_RS17925 a14b63d10cc9d131bcba4f0cfd20b30c 749 SUPERFAMILY SSF55326 19 204 3.14E-49 T 06-07-2017 SMD11_RS17925 a14b63d10cc9d131bcba4f0cfd20b30c 749 SUPERFAMILY SSF55326 408 578 1.57E-55 T 06-07-2017 SMD11_RS17925 a14b63d10cc9d131bcba4f0cfd20b30c 749 Gene3D G3DSA:3.30.1330.10 56 203 4.7E-53 T 06-07-2017 IPR016188 PurM-like, N-terminal domain SMD11_RS17925 a14b63d10cc9d131bcba4f0cfd20b30c 749 Gene3D G3DSA:3.30.1330.10 427 576 2.4E-52 T 06-07-2017 IPR016188 PurM-like, N-terminal domain SMD11_RS17925 a14b63d10cc9d131bcba4f0cfd20b30c 749 Pfam PF00586 AIR synthase related protein, N-terminal domain 467 572 1.8E-22 T 06-07-2017 IPR016188 PurM-like, N-terminal domain SMD11_RS17925 a14b63d10cc9d131bcba4f0cfd20b30c 749 Pfam PF00586 AIR synthase related protein, N-terminal domain 96 198 5.3E-22 T 06-07-2017 IPR016188 PurM-like, N-terminal domain SMD11_RS17925 a14b63d10cc9d131bcba4f0cfd20b30c 749 SUPERFAMILY SSF56042 583 747 5.08E-39 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain SMD11_RS17925 a14b63d10cc9d131bcba4f0cfd20b30c 749 SUPERFAMILY SSF56042 209 439 1.94E-52 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain SMD11_RS02445 64d8ecbad3a725f25b6fe296f71cafcf 632 Pfam PF00005 ABC transporter 397 546 3.9E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS02445 64d8ecbad3a725f25b6fe296f71cafcf 632 Pfam PF00664 ABC transporter transmembrane region 47 314 8.5E-43 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS02445 64d8ecbad3a725f25b6fe296f71cafcf 632 Gene3D G3DSA:1.20.1560.10 30 350 4.0E-73 T 06-07-2017 SMD11_RS02445 64d8ecbad3a725f25b6fe296f71cafcf 632 Gene3D G3DSA:3.40.50.300 362 610 3.5E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02445 64d8ecbad3a725f25b6fe296f71cafcf 632 ProSitePatterns PS00211 ABC transporters family signature. 518 532 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS02445 64d8ecbad3a725f25b6fe296f71cafcf 632 SUPERFAMILY SSF52540 361 617 7.35E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02445 64d8ecbad3a725f25b6fe296f71cafcf 632 SMART SM00382 406 592 1.6E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS02445 64d8ecbad3a725f25b6fe296f71cafcf 632 SUPERFAMILY SSF90123 30 350 1.27E-72 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS12860 c27bce2375b39b1dc4ffba605dc10722 440 SUPERFAMILY SSF53756 89 302 1.48E-7 T 06-07-2017 SMD11_RS16350 403caf7d35af0354cf986260037c3fe7 549 Gene3D G3DSA:3.30.9.10 169 270 4.2E-12 T 06-07-2017 SMD11_RS16350 403caf7d35af0354cf986260037c3fe7 549 Gene3D G3DSA:3.30.9.10 325 341 4.2E-12 T 06-07-2017 SMD11_RS16350 403caf7d35af0354cf986260037c3fe7 549 Pfam PF01494 FAD binding domain 5 341 3.0E-71 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS16350 403caf7d35af0354cf986260037c3fe7 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 1.9E-39 T 06-07-2017 SMD11_RS16350 403caf7d35af0354cf986260037c3fe7 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 328 344 1.9E-39 T 06-07-2017 SMD11_RS16350 403caf7d35af0354cf986260037c3fe7 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 310 328 1.9E-39 T 06-07-2017 SMD11_RS16350 403caf7d35af0354cf986260037c3fe7 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.9E-39 T 06-07-2017 SMD11_RS16350 403caf7d35af0354cf986260037c3fe7 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 1.9E-39 T 06-07-2017 SMD11_RS16350 403caf7d35af0354cf986260037c3fe7 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 1.9E-39 T 06-07-2017 SMD11_RS16350 403caf7d35af0354cf986260037c3fe7 549 SUPERFAMILY SSF51905 264 375 5.64E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS16350 403caf7d35af0354cf986260037c3fe7 549 SUPERFAMILY SSF51905 7 176 5.64E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS16350 403caf7d35af0354cf986260037c3fe7 549 Gene3D G3DSA:3.50.50.60 275 313 7.4E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS16350 403caf7d35af0354cf986260037c3fe7 549 Gene3D G3DSA:3.50.50.60 4 168 7.4E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13160 874b8e5bae7ed966144b2a22ed97053f 356 ProSitePatterns PS00211 ABC transporters family signature. 175 189 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS13160 874b8e5bae7ed966144b2a22ed97053f 356 Pfam PF00005 ABC transporter 55 202 1.8E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS13160 874b8e5bae7ed966144b2a22ed97053f 356 SUPERFAMILY SSF52540 48 279 6.98E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13160 874b8e5bae7ed966144b2a22ed97053f 356 Gene3D G3DSA:3.40.50.300 38 275 5.5E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13160 874b8e5bae7ed966144b2a22ed97053f 356 SMART SM00382 63 252 9.2E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS13160 874b8e5bae7ed966144b2a22ed97053f 356 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 47 291 5.4E-108 T 06-07-2017 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 SMD11_RS24680 11a0b7ee8cf191cda7ac37bf37a129e5 360 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 1 355 53.32 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SMD11_RS24680 11a0b7ee8cf191cda7ac37bf37a129e5 360 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 2 353 1.3E-95 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SMD11_RS24680 11a0b7ee8cf191cda7ac37bf37a129e5 360 Gene3D G3DSA:3.40.640.10 38 261 1.7E-65 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS24680 11a0b7ee8cf191cda7ac37bf37a129e5 360 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 218 227 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMD11_RS24680 11a0b7ee8cf191cda7ac37bf37a129e5 360 SUPERFAMILY SSF53383 19 352 8.57E-76 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS24680 11a0b7ee8cf191cda7ac37bf37a129e5 360 Pfam PF00155 Aminotransferase class I and II 20 351 4.4E-64 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS24680 11a0b7ee8cf191cda7ac37bf37a129e5 360 Gene3D G3DSA:3.90.1150.10 262 357 3.0E-17 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS12945 f8785a0159a0d603040b394bfadc606c 146 SUPERFAMILY SSF55729 1 130 1.05E-30 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS12945 f8785a0159a0d603040b394bfadc606c 146 Pfam PF00583 Acetyltransferase (GNAT) family 54 131 2.2E-16 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS12945 f8785a0159a0d603040b394bfadc606c 146 Gene3D G3DSA:3.40.630.30 2 131 7.8E-33 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS24225 d2d7d33b2767f39b09f80f91c4c72bdf 352 Pfam PF00355 Rieske [2Fe-2S] domain 238 323 1.9E-10 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS24225 d2d7d33b2767f39b09f80f91c4c72bdf 352 PRINTS PR00162 Rieske 2Fe-2S subunit signature 273 284 1.3E-5 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD11_RS24225 d2d7d33b2767f39b09f80f91c4c72bdf 352 PRINTS PR00162 Rieske 2Fe-2S subunit signature 309 321 1.3E-5 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD11_RS24225 d2d7d33b2767f39b09f80f91c4c72bdf 352 PRINTS PR00162 Rieske 2Fe-2S subunit signature 295 307 1.3E-5 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD11_RS24225 d2d7d33b2767f39b09f80f91c4c72bdf 352 SUPERFAMILY SSF50022 169 351 3.14E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS24225 d2d7d33b2767f39b09f80f91c4c72bdf 352 Gene3D G3DSA:2.102.10.10 208 351 3.6E-36 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS09460 cba6154adae57a6765a3938eefdd4d94 245 Pfam PF00005 ABC transporter 26 174 3.6E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS09460 cba6154adae57a6765a3938eefdd4d94 245 SUPERFAMILY SSF52540 9 223 1.2E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09460 cba6154adae57a6765a3938eefdd4d94 245 Gene3D G3DSA:3.40.50.300 5 223 4.0E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09460 cba6154adae57a6765a3938eefdd4d94 245 SMART SM00382 34 222 9.2E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS22920 4ef9caec518d14db0425d7e5cd384360 300 Gene3D G3DSA:1.10.260.40 31 110 2.1E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS22920 4ef9caec518d14db0425d7e5cd384360 300 Pfam PF13560 Helix-turn-helix domain 36 115 1.8E-15 T 06-07-2017 SMD11_RS01370 54286a6ab98c1a7041542239386d4027 425 Pfam PF14378 PAP2 superfamily 155 337 2.9E-19 T 06-07-2017 IPR026841 Inositolphosphotransferase Aur1/Ipt1 SMD11_RS10090 423a6dce5f063992dcc20b5e9f4719cd 390 Gene3D G3DSA:2.120.10.30 14 21 9.2E-89 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS10090 423a6dce5f063992dcc20b5e9f4719cd 390 Gene3D G3DSA:2.120.10.30 56 388 9.2E-89 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS10090 423a6dce5f063992dcc20b5e9f4719cd 390 Pfam PF07995 Glucose / Sorbosone dehydrogenase 76 374 1.6E-74 T 06-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 SMD11_RS10090 423a6dce5f063992dcc20b5e9f4719cd 390 SUPERFAMILY SSF50952 65 375 8.63E-49 T 06-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 SMD11_RS13680 8f2b75f51c42bd5a3d3182c263158069 342 Gene3D G3DSA:3.30.1330.40 203 333 5.9E-10 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD11_RS13680 8f2b75f51c42bd5a3d3182c263158069 342 SUPERFAMILY SSF55298 229 334 4.08E-11 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD11_RS13680 8f2b75f51c42bd5a3d3182c263158069 342 TIGRFAM TIGR04444 chori_FkbO_Hyg5: chorismatase, FkbO/Hyg5 family 23 335 9.1E-124 T 06-07-2017 IPR031038 Chorismatase, FkbO/Hyg5 family GO:0055114 SMD11_RS29125 9cce39497db32424a01c470d23ff02e5 338 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 5 128 1.4E-33 T 06-07-2017 IPR026992 Non-haem dioxygenase N-terminal domain SMD11_RS29125 9cce39497db32424a01c470d23ff02e5 338 SUPERFAMILY SSF51197 2 295 1.1E-83 T 06-07-2017 SMD11_RS29125 9cce39497db32424a01c470d23ff02e5 338 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 180 275 2.7E-20 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 SMD11_RS29125 9cce39497db32424a01c470d23ff02e5 338 PRINTS PR00682 Isopenicillin N synthase signature 234 260 6.1E-13 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 SMD11_RS29125 9cce39497db32424a01c470d23ff02e5 338 PRINTS PR00682 Isopenicillin N synthase signature 198 219 6.1E-13 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 SMD11_RS29125 9cce39497db32424a01c470d23ff02e5 338 PRINTS PR00682 Isopenicillin N synthase signature 27 44 6.1E-13 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 SMD11_RS29125 9cce39497db32424a01c470d23ff02e5 338 Gene3D G3DSA:2.60.120.330 2 293 2.3E-92 T 06-07-2017 IPR027443 Isopenicillin N synthase-like SMD11_RS03280 cbedc3111397023d8ef8ab8f9e72740d 136 Pfam PF12680 SnoaL-like domain 18 115 2.0E-13 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain SMD11_RS03280 cbedc3111397023d8ef8ab8f9e72740d 136 Gene3D G3DSA:3.10.450.50 12 118 2.3E-16 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS03280 cbedc3111397023d8ef8ab8f9e72740d 136 SUPERFAMILY SSF54427 12 120 1.83E-23 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS31285 1f4e7ab344f58d01ccfaf018a2055be6 644 SUPERFAMILY SSF52540 366 625 1.27E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31285 1f4e7ab344f58d01ccfaf018a2055be6 644 Pfam PF00005 ABC transporter 391 555 6.7E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS31285 1f4e7ab344f58d01ccfaf018a2055be6 644 Gene3D G3DSA:1.20.1560.10 172 342 1.9E-12 T 06-07-2017 SMD11_RS31285 1f4e7ab344f58d01ccfaf018a2055be6 644 SUPERFAMILY SSF90123 51 357 7.55E-15 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS31285 1f4e7ab344f58d01ccfaf018a2055be6 644 ProSitePatterns PS00211 ABC transporters family signature. 526 540 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS31285 1f4e7ab344f58d01ccfaf018a2055be6 644 Gene3D G3DSA:3.40.50.300 374 619 5.8E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31285 1f4e7ab344f58d01ccfaf018a2055be6 644 SMART SM00382 400 608 1.9E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS27930 86e1b831608d352753954786e8730f89 396 Pfam PF00067 Cytochrome P450 272 368 3.0E-13 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 Pfam PF00067 Cytochrome P450 180 264 9.0E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 SUPERFAMILY SSF48264 22 396 1.02E-97 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 PRINTS PR00385 P450 superfamily signature 348 359 3.7E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 PRINTS PR00385 P450 superfamily signature 236 253 3.7E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 PRINTS PR00385 P450 superfamily signature 271 282 3.7E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 PRINTS PR00385 P450 superfamily signature 339 348 3.7E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 PRINTS PR00359 B-class P450 signature 271 282 1.8E-61 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 PRINTS PR00359 B-class P450 signature 135 151 1.8E-61 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 PRINTS PR00359 B-class P450 signature 348 359 1.8E-61 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 PRINTS PR00359 B-class P450 signature 318 333 1.8E-61 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 PRINTS PR00359 B-class P450 signature 88 99 1.8E-61 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 PRINTS PR00359 B-class P450 signature 290 317 1.8E-61 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 PRINTS PR00359 B-class P450 signature 190 212 1.8E-61 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 PRINTS PR00359 B-class P450 signature 339 348 1.8E-61 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 PRINTS PR00359 B-class P450 signature 152 167 1.8E-61 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS27930 86e1b831608d352753954786e8730f89 396 Gene3D G3DSA:1.10.630.10 11 396 4.1E-128 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS33815 931d95f0109096caf8a578a90158e74f 407 Pfam PF00534 Glycosyl transferases group 1 218 362 5.7E-26 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 SMD11_RS33815 931d95f0109096caf8a578a90158e74f 407 Gene3D G3DSA:3.40.50.2000 192 361 3.0E-27 T 06-07-2017 SMD11_RS33815 931d95f0109096caf8a578a90158e74f 407 SUPERFAMILY SSF53756 1 392 5.23E-54 T 06-07-2017 SMD11_RS33815 931d95f0109096caf8a578a90158e74f 407 Pfam PF13579 Glycosyl transferase 4-like domain 25 185 1.4E-7 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 SMD11_RS09590 e0d5ec159b74ac23bce5bb3f95915bf3 271 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 271 100.419 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SMD11_RS09590 e0d5ec159b74ac23bce5bb3f95915bf3 271 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 236 8.9E-67 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SMD11_RS09590 e0d5ec159b74ac23bce5bb3f95915bf3 271 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 230 6.0E-71 T 06-07-2017 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SMD11_RS09590 e0d5ec159b74ac23bce5bb3f95915bf3 271 Gene3D G3DSA:3.40.1280.10 1 165 4.6E-64 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SMD11_RS09590 e0d5ec159b74ac23bce5bb3f95915bf3 271 SUPERFAMILY SSF75217 1 243 5.32E-84 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases SMD11_RS09590 e0d5ec159b74ac23bce5bb3f95915bf3 271 PIRSF PIRSF000386 1 256 1.0E-94 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SMD11_RS09590 e0d5ec159b74ac23bce5bb3f95915bf3 271 Gene3D G3DSA:1.10.1270.20 166 251 8.4E-28 T 06-07-2017 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SMD11_RS02505 02a612d227cd685ee030f8b2399d09f7 560 Gene3D G3DSA:3.40.309.10 317 513 2.5E-37 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS02505 02a612d227cd685ee030f8b2399d09f7 560 SUPERFAMILY SSF53720 82 522 4.84E-77 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS02505 02a612d227cd685ee030f8b2399d09f7 560 Pfam PF00171 Aldehyde dehydrogenase family 84 522 1.2E-62 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS02505 02a612d227cd685ee030f8b2399d09f7 560 Gene3D G3DSA:3.40.605.10 84 316 2.0E-37 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS20675 9a653ed6ce6ea2cdf59e3f485900fdf6 322 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 4 313 1.0E-126 T 06-07-2017 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 SMD11_RS20675 9a653ed6ce6ea2cdf59e3f485900fdf6 322 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 322 137.839 T 06-07-2017 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 SMD11_RS20675 9a653ed6ce6ea2cdf59e3f485900fdf6 322 Gene3D G3DSA:3.40.50.10680 88 320 3.9E-83 T 06-07-2017 SMD11_RS20675 9a653ed6ce6ea2cdf59e3f485900fdf6 322 SUPERFAMILY SSF142338 4 319 3.92E-87 T 06-07-2017 SMD11_RS20675 9a653ed6ce6ea2cdf59e3f485900fdf6 322 Gene3D G3DSA:3.50.50.60 1 34 5.8E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS20675 9a653ed6ce6ea2cdf59e3f485900fdf6 322 Pfam PF01933 Uncharacterised protein family UPF0052 4 278 2.5E-63 T 06-07-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 SMD11_RS11515 50739d244f2ef12af178ee61d7e8ab65 374 Pfam PF01370 NAD dependent epimerase/dehydratase family 30 240 1.4E-17 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 SMD11_RS11515 50739d244f2ef12af178ee61d7e8ab65 374 Gene3D G3DSA:3.40.50.720 26 240 3.6E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS11515 50739d244f2ef12af178ee61d7e8ab65 374 SUPERFAMILY SSF51735 28 330 8.0E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 Gene3D G3DSA:1.10.10.10 864 918 1.5E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 SUPERFAMILY SSF46894 864 921 2.93E-15 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 Pfam PF00196 Bacterial regulatory proteins, luxR family 867 918 4.6E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 Pfam PF13191 AAA ATPase domain 3 168 1.4E-17 T 06-07-2017 SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 ProSitePatterns PS00622 LuxR-type HTH domain signature. 882 909 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 Gene3D G3DSA:3.40.50.300 113 176 2.3E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 Gene3D G3DSA:3.40.50.300 11 69 2.3E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 SUPERFAMILY SSF52540 8 77 1.62E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 SUPERFAMILY SSF52540 133 245 1.62E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 868 882 3.6E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 882 898 3.6E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 898 910 3.6E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 Gene3D G3DSA:1.25.40.10 584 751 1.0E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 Gene3D G3DSA:1.25.40.10 787 847 1.0E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 Gene3D G3DSA:1.25.40.10 381 470 1.0E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 SUPERFAMILY SSF48452 614 832 1.4E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS08285 b8a382c766e1f1eb45b587040712c1d4 944 SMART SM00421 865 922 3.6E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28750 761313dc5b513e4d50349475a06d0b96 451 Gene3D G3DSA:3.10.580.10 210 330 8.4E-18 T 06-07-2017 SMD11_RS28750 761313dc5b513e4d50349475a06d0b96 451 SUPERFAMILY SSF56176 363 439 6.0E-16 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS28750 761313dc5b513e4d50349475a06d0b96 451 SMART SM01091 357 434 6.2E-18 T 06-07-2017 IPR005170 Transporter-associated domain SMD11_RS28750 761313dc5b513e4d50349475a06d0b96 451 SUPERFAMILY SSF54631 214 346 2.53E-25 T 06-07-2017 SMD11_RS28750 761313dc5b513e4d50349475a06d0b96 451 Pfam PF01595 Domain of unknown function DUF21 9 201 5.8E-30 T 06-07-2017 IPR002550 Domain of unknown function DUF21 SMD11_RS28750 761313dc5b513e4d50349475a06d0b96 451 Pfam PF00571 CBS domain 219 272 0.0068 T 06-07-2017 IPR000644 CBS domain SMD11_RS28750 761313dc5b513e4d50349475a06d0b96 451 Pfam PF00571 CBS domain 286 335 7.8E-6 T 06-07-2017 IPR000644 CBS domain SMD11_RS28750 761313dc5b513e4d50349475a06d0b96 451 Gene3D G3DSA:3.30.465.10 331 431 1.5E-22 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS28750 761313dc5b513e4d50349475a06d0b96 451 Pfam PF03471 Transporter associated domain 364 432 3.3E-16 T 06-07-2017 IPR005170 Transporter-associated domain SMD11_RS07590 34a5e2e912248a9dbdcb89e4c64ba32e 342 Gene3D G3DSA:2.115.10.10 255 342 3.2E-16 T 06-07-2017 IPR023294 Tachylectin 2 SMD11_RS07590 34a5e2e912248a9dbdcb89e4c64ba32e 342 Gene3D G3DSA:2.115.10.10 134 254 3.0E-9 T 06-07-2017 IPR023294 Tachylectin 2 SMD11_RS07590 34a5e2e912248a9dbdcb89e4c64ba32e 342 SUPERFAMILY SSF69318 111 325 2.49E-20 T 06-07-2017 SMD11_RS07590 34a5e2e912248a9dbdcb89e4c64ba32e 342 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 241 303 3.5E-9 T 06-07-2017 SMD11_RS30315 7b2160373290645ff4f44557578bf677 359 SUPERFAMILY SSF48576 35 357 1.54E-75 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS30315 7b2160373290645ff4f44557578bf677 359 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 93 107 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 SMD11_RS30315 7b2160373290645ff4f44557578bf677 359 Pfam PF00348 Polyprenyl synthetase 41 294 3.7E-55 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 SMD11_RS30315 7b2160373290645ff4f44557578bf677 359 Gene3D G3DSA:1.10.600.10 35 357 4.4E-84 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS30315 7b2160373290645ff4f44557578bf677 359 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 237 249 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 SMD11_RS26910 973ed087a330a8fcc6eaebf711fc583c 397 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 396 51.291 T 06-07-2017 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS26910 973ed087a330a8fcc6eaebf711fc583c 397 Pfam PF00764 Arginosuccinate synthase 6 391 2.1E-183 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS26910 973ed087a330a8fcc6eaebf711fc583c 397 SUPERFAMILY SSF69864 171 394 1.44E-83 T 06-07-2017 SMD11_RS26910 973ed087a330a8fcc6eaebf711fc583c 397 Gene3D G3DSA:3.90.1260.10 174 394 3.8E-81 T 06-07-2017 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS26910 973ed087a330a8fcc6eaebf711fc583c 397 SUPERFAMILY SSF52402 3 166 3.75E-41 T 06-07-2017 SMD11_RS26910 973ed087a330a8fcc6eaebf711fc583c 397 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS26910 973ed087a330a8fcc6eaebf711fc583c 397 Gene3D G3DSA:3.40.50.620 3 173 2.5E-54 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS26910 973ed087a330a8fcc6eaebf711fc583c 397 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS26910 973ed087a330a8fcc6eaebf711fc583c 397 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 392 3.1E-145 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SMD11_RS00150 8322f3de578a4361953d36ec27a5a96c 407 Gene3D G3DSA:1.20.1250.20 211 384 3.5E-19 T 06-07-2017 SMD11_RS00150 8322f3de578a4361953d36ec27a5a96c 407 Gene3D G3DSA:1.20.1250.20 14 201 1.3E-28 T 06-07-2017 SMD11_RS00150 8322f3de578a4361953d36ec27a5a96c 407 SUPERFAMILY SSF103473 8 383 9.16E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS00150 8322f3de578a4361953d36ec27a5a96c 407 Pfam PF07690 Major Facilitator Superfamily 22 353 2.0E-42 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS14380 5c558b68f0b2d1a4851bd5791a5ae2b3 625 Gene3D G3DSA:3.40.50.300 388 617 3.0E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14380 5c558b68f0b2d1a4851bd5791a5ae2b3 625 Pfam PF00664 ABC transporter transmembrane region 31 342 2.5E-61 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS14380 5c558b68f0b2d1a4851bd5791a5ae2b3 625 SMART SM00382 413 599 1.3E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS14380 5c558b68f0b2d1a4851bd5791a5ae2b3 625 ProSitePatterns PS00211 ABC transporters family signature. 525 539 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS14380 5c558b68f0b2d1a4851bd5791a5ae2b3 625 Pfam PF00005 ABC transporter 405 553 9.3E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS14380 5c558b68f0b2d1a4851bd5791a5ae2b3 625 SUPERFAMILY SSF90123 102 370 1.44E-85 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS14380 5c558b68f0b2d1a4851bd5791a5ae2b3 625 SUPERFAMILY SSF90123 17 61 1.44E-85 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS14380 5c558b68f0b2d1a4851bd5791a5ae2b3 625 Gene3D G3DSA:1.20.1560.10 103 373 3.2E-88 T 06-07-2017 SMD11_RS14380 5c558b68f0b2d1a4851bd5791a5ae2b3 625 Gene3D G3DSA:1.20.1560.10 17 69 3.2E-88 T 06-07-2017 SMD11_RS14380 5c558b68f0b2d1a4851bd5791a5ae2b3 625 SUPERFAMILY SSF52540 379 624 1.2E-90 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08705 f3a6c5340aad56d8b4233a5d6e0b578b 351 SUPERFAMILY SSF50494 20 260 5.31E-59 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS08705 f3a6c5340aad56d8b4233a5d6e0b578b 351 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 71 76 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD11_RS08705 f3a6c5340aad56d8b4233a5d6e0b578b 351 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 218 230 3.0E-13 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD11_RS08705 f3a6c5340aad56d8b4233a5d6e0b578b 351 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 61 76 3.0E-13 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD11_RS08705 f3a6c5340aad56d8b4233a5d6e0b578b 351 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 124 138 3.0E-13 T 06-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 SMD11_RS08705 f3a6c5340aad56d8b4233a5d6e0b578b 351 Gene3D G3DSA:2.40.10.10 134 261 1.5E-37 T 06-07-2017 SMD11_RS08705 f3a6c5340aad56d8b4233a5d6e0b578b 351 Gene3D G3DSA:2.40.10.10 67 133 3.8E-14 T 06-07-2017 SMD11_RS08705 f3a6c5340aad56d8b4233a5d6e0b578b 351 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 219 230 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site SMD11_RS08705 f3a6c5340aad56d8b4233a5d6e0b578b 351 SMART SM00020 27 264 2.4E-60 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD11_RS08705 f3a6c5340aad56d8b4233a5d6e0b578b 351 Gene3D G3DSA:2.40.10.10 28 66 2.4E-13 T 06-07-2017 SMD11_RS08705 f3a6c5340aad56d8b4233a5d6e0b578b 351 Pfam PF00089 Trypsin 28 259 4.5E-51 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD11_RS26105 3d967ad27e9786e2a1141fd52f326687 126 SMART SM00345 19 78 2.5E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS26105 3d967ad27e9786e2a1141fd52f326687 126 SUPERFAMILY SSF46785 8 82 2.43E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26105 3d967ad27e9786e2a1141fd52f326687 126 Gene3D G3DSA:1.10.10.10 5 79 2.4E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26105 3d967ad27e9786e2a1141fd52f326687 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 78 7.9E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS28575 9b822ebd3fc8f2ec022eac7eb1468a45 87 Pfam PF00037 4Fe-4S binding domain 36 57 3.1E-9 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD11_RS28575 9b822ebd3fc8f2ec022eac7eb1468a45 87 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 42 53 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD11_RS28575 9b822ebd3fc8f2ec022eac7eb1468a45 87 PRINTS PR00354 7Fe ferredoxin signature 37 54 4.5E-10 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 SMD11_RS28575 9b822ebd3fc8f2ec022eac7eb1468a45 87 PRINTS PR00354 7Fe ferredoxin signature 19 29 4.5E-10 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 SMD11_RS28575 9b822ebd3fc8f2ec022eac7eb1468a45 87 PRINTS PR00354 7Fe ferredoxin signature 9 19 4.5E-10 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 SMD11_RS28575 9b822ebd3fc8f2ec022eac7eb1468a45 87 Gene3D G3DSA:3.30.70.20 3 78 2.1E-18 T 06-07-2017 SMD11_RS28575 9b822ebd3fc8f2ec022eac7eb1468a45 87 SUPERFAMILY SSF54862 3 64 2.46E-19 T 06-07-2017 SMD11_RS12070 4d23abf001ce6d78ea7a89295e8339e7 250 SMART SM00345 12 71 3.9E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS12070 4d23abf001ce6d78ea7a89295e8339e7 250 SUPERFAMILY SSF64288 59 248 2.51E-21 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS12070 4d23abf001ce6d78ea7a89295e8339e7 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 1.6E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS12070 4d23abf001ce6d78ea7a89295e8339e7 250 SMART SM00866 98 242 4.3E-8 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS12070 4d23abf001ce6d78ea7a89295e8339e7 250 Gene3D G3DSA:3.40.1410.10 74 245 4.8E-48 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS12070 4d23abf001ce6d78ea7a89295e8339e7 250 Gene3D G3DSA:1.10.10.10 8 73 5.7E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12070 4d23abf001ce6d78ea7a89295e8339e7 250 Pfam PF07702 UTRA domain 111 242 3.8E-10 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS12070 4d23abf001ce6d78ea7a89295e8339e7 250 SUPERFAMILY SSF46785 4 83 6.46E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS18245 ae2faefced6fe8d8cdf9b7a0442c9f55 344 SUPERFAMILY SSF51735 1 314 4.04E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18245 ae2faefced6fe8d8cdf9b7a0442c9f55 344 Gene3D G3DSA:3.40.50.720 1 184 6.2E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18245 ae2faefced6fe8d8cdf9b7a0442c9f55 344 Pfam PF01370 NAD dependent epimerase/dehydratase family 1 233 3.7E-21 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 SMD11_RS11655 35d7452d9f01532983b1ab653fa587a3 304 Gene3D G3DSA:3.40.50.720 1 187 1.0E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS11655 35d7452d9f01532983b1ab653fa587a3 304 SUPERFAMILY SSF51735 1 297 4.48E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS11655 35d7452d9f01532983b1ab653fa587a3 304 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 222 9.5E-32 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 SMD11_RS11655 35d7452d9f01532983b1ab653fa587a3 304 Gene3D G3DSA:3.90.25.10 188 297 1.0E-14 T 06-07-2017 SMD11_RS13210 911eb9506afca5321a3a27085ab929db 289 Gene3D G3DSA:3.40.50.720 139 264 1.5E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS13210 911eb9506afca5321a3a27085ab929db 289 SUPERFAMILY SSF53223 1 121 8.25E-36 T 06-07-2017 SMD11_RS13210 911eb9506afca5321a3a27085ab929db 289 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 2.2E-33 T 06-07-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD11_RS13210 911eb9506afca5321a3a27085ab929db 289 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 35.489 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD11_RS13210 911eb9506afca5321a3a27085ab929db 289 SUPERFAMILY SSF51735 122 281 4.13E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS13210 911eb9506afca5321a3a27085ab929db 289 Gene3D G3DSA:3.40.192.10 7 138 1.4E-42 T 06-07-2017 SMD11_RS13210 911eb9506afca5321a3a27085ab929db 289 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 282 7.8E-60 T 06-07-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD11_RS13210 911eb9506afca5321a3a27085ab929db 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 2.0E-58 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD11_RS13210 911eb9506afca5321a3a27085ab929db 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 2.0E-58 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD11_RS13210 911eb9506afca5321a3a27085ab929db 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 2.0E-58 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD11_RS13210 911eb9506afca5321a3a27085ab929db 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 2.0E-58 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD11_RS13210 911eb9506afca5321a3a27085ab929db 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 2.0E-58 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD11_RS13210 911eb9506afca5321a3a27085ab929db 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 2.0E-58 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SMD11_RS30195 8e92068dc8af2851199ff45a0453d4f1 482 SUPERFAMILY SSF54862 420 478 1.67E-5 T 06-07-2017 SMD11_RS30195 8e92068dc8af2851199ff45a0453d4f1 482 Gene3D G3DSA:3.30.70.20 421 480 1.4E-5 T 06-07-2017 SMD11_RS30195 8e92068dc8af2851199ff45a0453d4f1 482 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 27 187 1.3E-27 T 06-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS30195 8e92068dc8af2851199ff45a0453d4f1 482 SUPERFAMILY SSF140490 286 383 1.23E-15 T 06-07-2017 SMD11_RS30195 8e92068dc8af2851199ff45a0453d4f1 482 Pfam PF13459 4Fe-4S single cluster domain 422 478 2.1E-8 T 06-07-2017 SMD11_RS30195 8e92068dc8af2851199ff45a0453d4f1 482 SUPERFAMILY SSF142984 214 283 3.92E-7 T 06-07-2017 SMD11_RS30195 8e92068dc8af2851199ff45a0453d4f1 482 SUPERFAMILY SSF142019 14 209 5.49E-36 T 06-07-2017 SMD11_RS30195 8e92068dc8af2851199ff45a0453d4f1 482 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 295 374 1.2E-15 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS30195 8e92068dc8af2851199ff45a0453d4f1 482 SMART SM00928 290 334 0.0028 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS22820 db0a655c5974be3e87a2e8cf0a3cb43e 246 SUPERFAMILY SSF158682 177 242 7.98E-7 T 06-07-2017 IPR029024 TerB-like SMD11_RS22820 db0a655c5974be3e87a2e8cf0a3cb43e 246 Gene3D G3DSA:1.10.3680.10 191 239 7.1E-5 T 06-07-2017 IPR029024 TerB-like SMD11_RS22820 db0a655c5974be3e87a2e8cf0a3cb43e 246 Pfam PF05099 Tellurite resistance protein TerB 129 237 4.0E-7 T 06-07-2017 IPR007791 Co-chaperone DjlA, N-terminal SMD11_RS12470 99ec4c7b1f5a5c93db2e38450125d798 160 SMART SM00347 41 132 1.6E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS12470 99ec4c7b1f5a5c93db2e38450125d798 160 Gene3D G3DSA:1.10.10.10 38 148 1.0E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12470 99ec4c7b1f5a5c93db2e38450125d798 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 1.6E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS12470 99ec4c7b1f5a5c93db2e38450125d798 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 1.6E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS12470 99ec4c7b1f5a5c93db2e38450125d798 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 1.6E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS12470 99ec4c7b1f5a5c93db2e38450125d798 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 122 142 1.6E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS12470 99ec4c7b1f5a5c93db2e38450125d798 160 SUPERFAMILY SSF46785 33 147 2.7E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12470 99ec4c7b1f5a5c93db2e38450125d798 160 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 37 89 0.006 T 06-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 SMD11_RS12470 99ec4c7b1f5a5c93db2e38450125d798 160 Pfam PF01047 MarR family 42 97 1.5E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS12470 99ec4c7b1f5a5c93db2e38450125d798 160 ProSitePatterns PS01117 MarR-type HTH domain signature. 71 105 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site SMD11_RS16860 4fbf27edb211b0a5f08bdf4aef6dbbc2 205 Pfam PF00583 Acetyltransferase (GNAT) family 65 139 2.3E-9 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS16860 4fbf27edb211b0a5f08bdf4aef6dbbc2 205 Gene3D G3DSA:3.40.630.30 5 135 7.3E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS16860 4fbf27edb211b0a5f08bdf4aef6dbbc2 205 SUPERFAMILY SSF55729 1 140 5.23E-13 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS32775 ad5a26a1f8f15c0d6326b0ed65029b0f 459 Gene3D G3DSA:2.130.10.10 317 448 1.0E-6 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS32775 ad5a26a1f8f15c0d6326b0ed65029b0f 459 Gene3D G3DSA:2.130.10.10 58 248 3.1E-15 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS32775 ad5a26a1f8f15c0d6326b0ed65029b0f 459 SUPERFAMILY SSF69322 290 449 1.23E-16 T 06-07-2017 SMD11_RS32775 ad5a26a1f8f15c0d6326b0ed65029b0f 459 SUPERFAMILY SSF69322 57 248 1.23E-16 T 06-07-2017 SMD11_RS32775 ad5a26a1f8f15c0d6326b0ed65029b0f 459 Pfam PF07676 WD40-like Beta Propeller Repeat 171 196 0.021 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS03195 b408726f312dd52bf961b582ce158e55 369 PRINTS PR00502 NUDIX hydrolase family signature 249 263 3.3E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS03195 b408726f312dd52bf961b582ce158e55 369 PRINTS PR00502 NUDIX hydrolase family signature 263 278 3.3E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS03195 b408726f312dd52bf961b582ce158e55 369 Gene3D G3DSA:3.90.79.10 224 354 3.6E-23 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS03195 b408726f312dd52bf961b582ce158e55 369 SUPERFAMILY SSF55811 224 351 1.11E-22 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS03195 b408726f312dd52bf961b582ce158e55 369 Pfam PF00293 NUDIX domain 225 344 5.7E-17 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS03195 b408726f312dd52bf961b582ce158e55 369 SUPERFAMILY SSF52540 25 204 2.13E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03195 b408726f312dd52bf961b582ce158e55 369 Gene3D G3DSA:3.40.50.300 26 207 7.7E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03195 b408726f312dd52bf961b582ce158e55 369 Pfam PF13671 AAA domain 27 155 4.2E-8 T 06-07-2017 SMD11_RS08090 9733c5720d81976860e0adebf6ed0eaa 343 SUPERFAMILY SSF51735 20 337 2.91E-95 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08090 9733c5720d81976860e0adebf6ed0eaa 343 Pfam PF16363 GDP-mannose 4,6 dehydratase 22 325 1.3E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08090 9733c5720d81976860e0adebf6ed0eaa 343 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 20 339 8.4E-123 T 06-07-2017 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 SMD11_RS08090 9733c5720d81976860e0adebf6ed0eaa 343 Gene3D G3DSA:3.90.25.10 201 337 1.0E-47 T 06-07-2017 SMD11_RS08090 9733c5720d81976860e0adebf6ed0eaa 343 Gene3D G3DSA:3.40.50.720 19 200 1.4E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08135 3ecc431a6f4f1f3b0ffebaf4b7364be6 271 SUPERFAMILY SSF48179 169 268 2.55E-26 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS08135 3ecc431a6f4f1f3b0ffebaf4b7364be6 271 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 170 266 1.4E-28 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS08135 3ecc431a6f4f1f3b0ffebaf4b7364be6 271 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1 167 2.2E-37 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS08135 3ecc431a6f4f1f3b0ffebaf4b7364be6 271 PIRSF PIRSF000105 1 270 3.4E-69 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 SMD11_RS08135 3ecc431a6f4f1f3b0ffebaf4b7364be6 271 SUPERFAMILY SSF51735 1 169 1.82E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08135 3ecc431a6f4f1f3b0ffebaf4b7364be6 271 Gene3D G3DSA:1.10.1040.10 172 267 7.4E-28 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS08135 3ecc431a6f4f1f3b0ffebaf4b7364be6 271 Gene3D G3DSA:3.40.50.720 1 171 2.3E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18795 bcf7b1131b9ef5bc68d8a9a3f00847b2 347 SUPERFAMILY SSF51556 15 344 1.56E-67 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS18795 bcf7b1131b9ef5bc68d8a9a3f00847b2 347 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 18 339 1.5E-112 T 06-07-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 SMD11_RS18795 bcf7b1131b9ef5bc68d8a9a3f00847b2 347 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 285 291 - T 06-07-2017 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: R-HSA-74217 SMD11_RS18795 bcf7b1131b9ef5bc68d8a9a3f00847b2 347 Pfam PF00962 Adenosine/AMP deaminase 18 339 2.1E-91 T 06-07-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 SMD11_RS18795 bcf7b1131b9ef5bc68d8a9a3f00847b2 347 Gene3D G3DSA:3.20.20.140 15 344 7.4E-82 T 06-07-2017 SMD11_RS04960 05f1088af1d61b0c69ba556ea7dbbc9c 111 Gene3D G3DSA:1.10.10.10 40 99 5.6E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04960 05f1088af1d61b0c69ba556ea7dbbc9c 111 Pfam PF08281 Sigma-70, region 4 45 95 5.6E-13 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS04960 05f1088af1d61b0c69ba556ea7dbbc9c 111 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 97 1.5E-12 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS04960 05f1088af1d61b0c69ba556ea7dbbc9c 111 SUPERFAMILY SSF88659 37 98 6.76E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS28190 db4f585a5c69227e783d03ee84b2efbb 458 Gene3D G3DSA:1.10.150.20 170 239 7.3E-19 T 06-07-2017 SMD11_RS28190 db4f585a5c69227e783d03ee84b2efbb 458 Gene3D G3DSA:3.30.70.270 68 167 2.0E-23 T 06-07-2017 SMD11_RS28190 db4f585a5c69227e783d03ee84b2efbb 458 SUPERFAMILY SSF100879 243 342 2.51E-25 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMD11_RS28190 db4f585a5c69227e783d03ee84b2efbb 458 Hamap MF_01113 DNA polymerase IV [dinB]. 4 352 34.721 T 06-07-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 SMD11_RS28190 db4f585a5c69227e783d03ee84b2efbb 458 Pfam PF11799 impB/mucB/samB family C-terminal domain 241 346 1.2E-20 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMD11_RS28190 db4f585a5c69227e783d03ee84b2efbb 458 SUPERFAMILY SSF56672 6 239 2.4E-70 T 06-07-2017 SMD11_RS28190 db4f585a5c69227e783d03ee84b2efbb 458 Pfam PF00817 impB/mucB/samB family 10 158 9.8E-45 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMD11_RS28190 db4f585a5c69227e783d03ee84b2efbb 458 Gene3D G3DSA:3.30.1490.100 246 352 1.8E-29 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 Pfam PF00704 Glycosyl hydrolases family 18 86 538 3.9E-80 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 Gene3D G3DSA:3.10.50.10 402 445 6.0E-18 T 06-07-2017 IPR029070 Chitinase insertion domain SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 Gene3D G3DSA:3.10.50.10 485 504 6.0E-18 T 06-07-2017 IPR029070 Chitinase insertion domain SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 SMART SM00636 85 538 8.1E-119 T 06-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 SUPERFAMILY SSF51445 510 542 5.69E-77 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 SUPERFAMILY SSF51445 79 395 5.69E-77 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 Gene3D G3DSA:3.20.20.80 505 563 1.6E-93 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 Gene3D G3DSA:3.20.20.80 83 344 1.6E-93 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 Gene3D G3DSA:3.20.20.80 461 462 1.6E-93 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 Gene3D G3DSA:3.20.20.80 378 401 1.6E-93 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 Gene3D G3DSA:2.10.10.20 742 790 1.7E-17 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 SUPERFAMILY SSF51055 741 793 8.44E-13 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 Pfam PF06483 Chitinase C 547 719 5.1E-75 T 06-07-2017 IPR009470 Chitinase, C-terminal KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 SMART SM00495 745 790 1.6E-9 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 Pfam PF02839 Carbohydrate binding domain 745 787 2.1E-8 T 06-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 SUPERFAMILY SSF54556 395 508 2.15E-12 T 06-07-2017 IPR029070 Chitinase insertion domain SMD11_RS27490 bd5f5e755ee6f0e63cb95d2c01b9d761 793 ProSitePatterns PS01095 Chitinases family 18 active site. 237 245 - T 06-07-2017 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 SMD11_RS03835 4b94fbf970cbc6208f003e09a3c6e7ff 218 Gene3D G3DSA:1.10.10.60 25 79 2.9E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS03835 4b94fbf970cbc6208f003e09a3c6e7ff 218 SUPERFAMILY SSF48498 102 215 9.79E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS03835 4b94fbf970cbc6208f003e09a3c6e7ff 218 Gene3D G3DSA:1.10.357.10 80 217 2.8E-46 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS03835 4b94fbf970cbc6208f003e09a3c6e7ff 218 SUPERFAMILY SSF46689 26 105 1.8E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS03835 4b94fbf970cbc6208f003e09a3c6e7ff 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 80 3.7E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS03835 4b94fbf970cbc6208f003e09a3c6e7ff 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 2.0E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS03835 4b94fbf970cbc6208f003e09a3c6e7ff 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 2.0E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS10000 40bf76665a9f36cbb592ddd8b402ee2d 308 PIRSF PIRSF000196 1 308 1.6E-113 T 06-07-2017 IPR008219 Proline dehydrogenase GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 SMD11_RS10000 40bf76665a9f36cbb592ddd8b402ee2d 308 Gene3D G3DSA:3.20.20.220 34 302 1.6E-64 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like SMD11_RS10000 40bf76665a9f36cbb592ddd8b402ee2d 308 SUPERFAMILY SSF51730 35 304 2.63E-66 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like SMD11_RS10000 40bf76665a9f36cbb592ddd8b402ee2d 308 Pfam PF01619 Proline dehydrogenase 46 299 1.4E-27 T 06-07-2017 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 SMD11_RS22785 6cb9eae474cc81d3c12a76a02905e9d2 314 Gene3D G3DSA:1.10.260.40 32 109 2.3E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS22785 6cb9eae474cc81d3c12a76a02905e9d2 314 SMART SM00530 36 113 1.3E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS22785 6cb9eae474cc81d3c12a76a02905e9d2 314 Pfam PF13560 Helix-turn-helix domain 60 116 1.1E-15 T 06-07-2017 SMD11_RS22785 6cb9eae474cc81d3c12a76a02905e9d2 314 SUPERFAMILY SSF47413 61 109 1.31E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS10365 fc766ef5bc1b2a0454355faff1129d27 406 SUPERFAMILY SSF56601 54 381 9.55E-79 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS10365 fc766ef5bc1b2a0454355faff1129d27 406 Gene3D G3DSA:3.40.710.10 54 381 3.7E-78 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS10365 fc766ef5bc1b2a0454355faff1129d27 406 Pfam PF00144 Beta-lactamase 57 366 6.8E-60 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS07925 147bcc297052b84e2b67f13ead4067bb 770 SUPERFAMILY SSF51905 19 167 3.08E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07925 147bcc297052b84e2b67f13ead4067bb 770 SUPERFAMILY SSF51905 270 357 3.08E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07925 147bcc297052b84e2b67f13ead4067bb 770 Gene3D G3DSA:3.50.50.60 273 395 2.0E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07925 147bcc297052b84e2b67f13ead4067bb 770 Gene3D G3DSA:3.50.50.60 113 174 2.0E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07925 147bcc297052b84e2b67f13ead4067bb 770 Gene3D G3DSA:3.50.50.60 19 59 2.0E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07925 147bcc297052b84e2b67f13ead4067bb 770 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 7.1E-14 T 06-07-2017 SMD11_RS07925 147bcc297052b84e2b67f13ead4067bb 770 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 19 41 7.1E-14 T 06-07-2017 SMD11_RS07925 147bcc297052b84e2b67f13ead4067bb 770 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 331 347 7.1E-14 T 06-07-2017 SMD11_RS07925 147bcc297052b84e2b67f13ead4067bb 770 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 7.1E-14 T 06-07-2017 SMD11_RS07925 147bcc297052b84e2b67f13ead4067bb 770 SUPERFAMILY SSF51395 403 749 4.1E-112 T 06-07-2017 SMD11_RS07925 147bcc297052b84e2b67f13ead4067bb 770 Gene3D G3DSA:3.20.20.70 404 745 2.5E-117 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS07925 147bcc297052b84e2b67f13ead4067bb 770 Pfam PF13450 NAD(P)-binding Rossmann-like domain 22 51 1.3E-4 T 06-07-2017 SMD11_RS07925 147bcc297052b84e2b67f13ead4067bb 770 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 407 740 2.6E-55 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMD11_RS07925 147bcc297052b84e2b67f13ead4067bb 770 Pfam PF01494 FAD binding domain 148 343 2.3E-14 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS11550 e609a654a3698c940bccb547d40a6326 379 Pfam PF00899 ThiF family 130 356 2.0E-13 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SMD11_RS11550 e609a654a3698c940bccb547d40a6326 379 Gene3D G3DSA:3.40.50.720 129 197 1.7E-5 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS11550 e609a654a3698c940bccb547d40a6326 379 SUPERFAMILY SSF69572 128 355 1.44E-11 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SMD11_RS09375 425a6f0649b4d8c3c454785bf6cb36c9 198 SUPERFAMILY SSF143990 32 196 4.45E-50 T 06-07-2017 SMD11_RS09375 425a6f0649b4d8c3c454785bf6cb36c9 198 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 35 194 7.2E-50 T 06-07-2017 IPR012816 NADAR SMD11_RS09375 425a6f0649b4d8c3c454785bf6cb36c9 198 Pfam PF08719 Domain of unknown function (DUF1768) 37 194 2.6E-51 T 06-07-2017 IPR012816 NADAR SMD11_RS28905 16aa721c9aa56ba91e9703c9c1be6dec 941 Gene3D G3DSA:1.10.10.10 852 910 1.0E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28905 16aa721c9aa56ba91e9703c9c1be6dec 941 SUPERFAMILY SSF46894 846 910 1.67E-15 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS28905 16aa721c9aa56ba91e9703c9c1be6dec 941 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 869 885 2.4E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28905 16aa721c9aa56ba91e9703c9c1be6dec 941 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 885 897 2.4E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28905 16aa721c9aa56ba91e9703c9c1be6dec 941 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 855 869 2.4E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28905 16aa721c9aa56ba91e9703c9c1be6dec 941 SUPERFAMILY SSF52540 101 222 2.28E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28905 16aa721c9aa56ba91e9703c9c1be6dec 941 SUPERFAMILY SSF52540 11 73 2.28E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28905 16aa721c9aa56ba91e9703c9c1be6dec 941 Pfam PF00196 Bacterial regulatory proteins, luxR family 854 909 1.9E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28905 16aa721c9aa56ba91e9703c9c1be6dec 941 Gene3D G3DSA:3.40.50.300 108 142 3.2E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28905 16aa721c9aa56ba91e9703c9c1be6dec 941 Gene3D G3DSA:3.40.50.300 12 70 3.2E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28905 16aa721c9aa56ba91e9703c9c1be6dec 941 Pfam PF13191 AAA ATPase domain 5 143 4.4E-16 T 06-07-2017 SMD11_RS28905 16aa721c9aa56ba91e9703c9c1be6dec 941 Gene3D G3DSA:1.25.40.10 601 813 3.3E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS28905 16aa721c9aa56ba91e9703c9c1be6dec 941 Gene3D G3DSA:1.25.40.10 420 439 3.3E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS28905 16aa721c9aa56ba91e9703c9c1be6dec 941 SMART SM00421 852 909 1.2E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS14655 3a61ffd0e7ec576fbeecb3659daeb730 323 SUPERFAMILY SSF51735 104 283 4.97E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS14655 3a61ffd0e7ec576fbeecb3659daeb730 323 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 32 311 3.6E-8 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMD11_RS14655 3a61ffd0e7ec576fbeecb3659daeb730 323 SUPERFAMILY SSF52283 23 131 4.86E-12 T 06-07-2017 SMD11_RS14655 3a61ffd0e7ec576fbeecb3659daeb730 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 283 6.9E-43 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMD11_RS14655 3a61ffd0e7ec576fbeecb3659daeb730 323 Gene3D G3DSA:3.40.50.720 12 111 1.6E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS14655 3a61ffd0e7ec576fbeecb3659daeb730 323 Gene3D G3DSA:3.40.50.720 112 284 2.4E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS09820 eb82c00160de5eadf1c25eca989180d0 212 Pfam PF13411 MerR HTH family regulatory protein 1 69 8.1E-14 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS09820 eb82c00160de5eadf1c25eca989180d0 212 SMART SM00422 1 71 2.8E-4 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS09820 eb82c00160de5eadf1c25eca989180d0 212 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.4E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS09820 eb82c00160de5eadf1c25eca989180d0 212 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.4E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS09820 eb82c00160de5eadf1c25eca989180d0 212 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.4E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS09820 eb82c00160de5eadf1c25eca989180d0 212 Gene3D G3DSA:1.10.1660.10 1 85 2.3E-15 T 06-07-2017 SMD11_RS09820 eb82c00160de5eadf1c25eca989180d0 212 SUPERFAMILY SSF46955 1 85 2.75E-12 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS13370 e2adc21f2f93487d2c6d296f1a14ee64 542 Gene3D G3DSA:3.40.309.10 293 472 1.8E-64 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS13370 e2adc21f2f93487d2c6d296f1a14ee64 542 Pfam PF00171 Aldehyde dehydrogenase family 54 506 9.0E-141 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS13370 e2adc21f2f93487d2c6d296f1a14ee64 542 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 278 285 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS13370 e2adc21f2f93487d2c6d296f1a14ee64 542 Gene3D G3DSA:3.40.605.10 55 292 1.9E-68 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS13370 e2adc21f2f93487d2c6d296f1a14ee64 542 SUPERFAMILY SSF53720 47 509 2.75E-139 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS18620 eba4ba20c2c5081a6c522ada40eb4821 419 SUPERFAMILY SSF56059 140 348 1.48E-21 T 06-07-2017 SMD11_RS18620 eba4ba20c2c5081a6c522ada40eb4821 419 Gene3D G3DSA:3.30.1490.20 135 219 2.2E-5 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS18620 eba4ba20c2c5081a6c522ada40eb4821 419 Gene3D G3DSA:3.30.470.20 231 335 2.7E-10 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS27790 aacefa30b575089a12a1158b24507f14 354 Pfam PF01032 FecCD transport family 30 347 5.4E-96 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD11_RS27790 aacefa30b575089a12a1158b24507f14 354 SUPERFAMILY SSF81345 19 349 9.42E-83 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS27790 aacefa30b575089a12a1158b24507f14 354 Gene3D G3DSA:1.10.3470.10 20 351 1.7E-108 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS18690 1a6969d713135f706b47918cae7e289b 250 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 90 199 1.2E-23 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18690 1a6969d713135f706b47918cae7e289b 250 Gene3D G3DSA:3.40.50.700 73 205 2.6E-36 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18690 1a6969d713135f706b47918cae7e289b 250 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 29 204 40.236 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18690 1a6969d713135f706b47918cae7e289b 250 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 69 205 2.5E-66 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18690 1a6969d713135f706b47918cae7e289b 250 SUPERFAMILY SSF56770 69 209 2.22E-61 T 06-07-2017 SMD11_RS20200 89d674e4308277ed2a6204e298291dd8 325 SMART SM00860 160 297 7.2E-5 T 06-07-2017 IPR018958 SMI1/KNR4-like domain SMD11_RS20200 89d674e4308277ed2a6204e298291dd8 325 Pfam PF14414 A nuclease of the HNH/ENDO VII superfamily with conserved WHH 96 131 2.9E-12 T 06-07-2017 IPR032869 WHH domain-containing protein SMD11_RS20200 89d674e4308277ed2a6204e298291dd8 325 SUPERFAMILY SSF160631 160 297 1.23E-15 T 06-07-2017 SMD11_RS20200 89d674e4308277ed2a6204e298291dd8 325 Gene3D G3DSA:3.40.1580.10 160 192 3.0E-6 T 06-07-2017 IPR018958 SMI1/KNR4-like domain SMD11_RS20200 89d674e4308277ed2a6204e298291dd8 325 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 161 295 1.1E-8 T 06-07-2017 IPR018958 SMI1/KNR4-like domain SMD11_RS09540 2c4c67a5861a7b964710bbc17a832257 392 Gene3D G3DSA:3.40.50.450 119 263 7.6E-14 T 06-07-2017 SMD11_RS09540 2c4c67a5861a7b964710bbc17a832257 392 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 74 291 1.1E-63 T 06-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 SMD11_RS09540 2c4c67a5861a7b964710bbc17a832257 392 SUPERFAMILY SSF102405 85 292 4.27E-38 T 06-07-2017 SMD11_RS09540 2c4c67a5861a7b964710bbc17a832257 392 Gene3D G3DSA:1.10.10.10 319 368 8.4E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS09540 2c4c67a5861a7b964710bbc17a832257 392 Pfam PF02481 DNA recombination-mediator protein A 77 284 1.2E-68 T 06-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 SMD11_RS25610 eabdd04b728cc3a3e0dbfe7ae4ab42d0 231 Gene3D G3DSA:1.10.530.10 152 228 6.0E-9 T 06-07-2017 SMD11_RS25610 eabdd04b728cc3a3e0dbfe7ae4ab42d0 231 SUPERFAMILY SSF53955 123 225 1.2E-13 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS25610 eabdd04b728cc3a3e0dbfe7ae4ab42d0 231 Pfam PF01464 Transglycosylase SLT domain 156 228 1.2E-8 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 SMD11_RS14605 d3e12e34eca72eb7922a14e4a5863add 242 SUPERFAMILY SSF48317 14 190 1.09E-32 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS14605 d3e12e34eca72eb7922a14e4a5863add 242 SMART SM00014 78 186 1.2E-13 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS14605 d3e12e34eca72eb7922a14e4a5863add 242 Gene3D G3DSA:1.20.144.10 22 185 1.3E-28 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS14605 d3e12e34eca72eb7922a14e4a5863add 242 Pfam PF01569 PAP2 superfamily 82 186 3.4E-16 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS27515 3ab1b38708619151817d2785c23d0baf 161 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 156 28.001 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD11_RS27515 3ab1b38708619151817d2785c23d0baf 161 SUPERFAMILY SSF52121 11 156 1.96E-54 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD11_RS27515 3ab1b38708619151817d2785c23d0baf 161 Gene3D G3DSA:3.40.50.960 12 157 1.7E-58 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD11_RS27515 3ab1b38708619151817d2785c23d0baf 161 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 151 3.0E-42 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD11_RS27515 3ab1b38708619151817d2785c23d0baf 161 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 152 1.0E-50 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD11_RS28795 27254b227c668a52bf07c4455831d69c 145 Pfam PF13581 Histidine kinase-like ATPase domain 12 134 3.0E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS28795 27254b227c668a52bf07c4455831d69c 145 Gene3D G3DSA:3.30.565.10 18 138 1.4E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS28795 27254b227c668a52bf07c4455831d69c 145 SUPERFAMILY SSF55874 33 137 1.62E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS29745 41fc1627cbebe4411587948f476c42ff 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.0E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS29745 41fc1627cbebe4411587948f476c42ff 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.0E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS29745 41fc1627cbebe4411587948f476c42ff 229 SUPERFAMILY SSF48498 76 204 8.9E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS29745 41fc1627cbebe4411587948f476c42ff 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 5.3E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS29745 41fc1627cbebe4411587948f476c42ff 229 SUPERFAMILY SSF46689 4 65 1.54E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS29745 41fc1627cbebe4411587948f476c42ff 229 Gene3D G3DSA:1.10.357.10 3 186 4.3E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS29745 41fc1627cbebe4411587948f476c42ff 229 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD11_RS08885 94549072a72250aaf1a8b53a8728d4cc 236 SUPERFAMILY SSF53213 13 236 4.19E-7 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 PRINTS PR00819 CbxX/CfqX superfamily signature 352 366 4.4E-50 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 PRINTS PR00819 CbxX/CfqX superfamily signature 498 515 4.4E-50 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 PRINTS PR00819 CbxX/CfqX superfamily signature 444 463 4.4E-50 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 PRINTS PR00819 CbxX/CfqX superfamily signature 477 489 4.4E-50 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 PRINTS PR00819 CbxX/CfqX superfamily signature 430 444 4.4E-50 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 PRINTS PR00819 CbxX/CfqX superfamily signature 575 587 4.4E-50 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 PRINTS PR00819 CbxX/CfqX superfamily signature 392 407 4.4E-50 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 PRINTS PR00819 CbxX/CfqX superfamily signature 515 534 4.4E-50 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 394 527 2.7E-13 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 Gene3D G3DSA:1.25.40.10 8 52 8.4E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 Gene3D G3DSA:1.25.40.10 176 250 8.4E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 SMART SM00382 389 530 3.8E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 SUPERFAMILY SSF48452 175 243 3.23E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 SUPERFAMILY SSF48452 12 51 3.23E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 Gene3D G3DSA:3.40.50.300 352 527 2.6E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27545 f9e45de754c79ae19cb81b937e662813 641 SUPERFAMILY SSF52540 353 597 8.1E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30865 5078f56a957dcf5dca874127fa15738c 956 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 296 452 5.5E-26 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS30865 5078f56a957dcf5dca874127fa15738c 956 SUPERFAMILY SSF69304 649 916 2.88E-9 T 06-07-2017 SMD11_RS30865 5078f56a957dcf5dca874127fa15738c 956 Gene3D G3DSA:3.10.170.10 296 459 8.8E-23 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS30865 5078f56a957dcf5dca874127fa15738c 956 Gene3D G3DSA:1.10.390.10 463 615 3.8E-18 T 06-07-2017 SMD11_RS30865 5078f56a957dcf5dca874127fa15738c 956 Gene3D G3DSA:2.120.10.30 647 838 1.1E-8 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS30865 5078f56a957dcf5dca874127fa15738c 956 SUPERFAMILY SSF55486 294 613 2.75E-41 T 06-07-2017 SMD11_RS30865 5078f56a957dcf5dca874127fa15738c 956 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 459 613 2.2E-19 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 SMD11_RS20355 0c42c7523d3680a2574fe5cb7cf154e5 805 SUPERFAMILY SSF51735 229 271 2.42E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20355 0c42c7523d3680a2574fe5cb7cf154e5 805 SUPERFAMILY SSF51735 316 469 2.42E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20355 0c42c7523d3680a2574fe5cb7cf154e5 805 SUPERFAMILY SSF51735 11 211 7.65E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20355 0c42c7523d3680a2574fe5cb7cf154e5 805 Pfam PF08659 KR domain 233 451 6.6E-22 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS20355 0c42c7523d3680a2574fe5cb7cf154e5 805 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 231 453 1.7E-13 T 06-07-2017 SMD11_RS20355 0c42c7523d3680a2574fe5cb7cf154e5 805 Gene3D G3DSA:3.40.50.720 311 475 3.5E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20355 0c42c7523d3680a2574fe5cb7cf154e5 805 Gene3D G3DSA:3.40.50.720 231 264 3.5E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19250 5e671cd532bc3faaca485869e5a8630e 203 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS19250 5e671cd532bc3faaca485869e5a8630e 203 SMART SM00448 2 115 4.9E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS19250 5e671cd532bc3faaca485869e5a8630e 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 194 3.5E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS19250 5e671cd532bc3faaca485869e5a8630e 203 Gene3D G3DSA:1.10.10.10 144 201 7.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19250 5e671cd532bc3faaca485869e5a8630e 203 SUPERFAMILY SSF46894 128 202 2.79E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS19250 5e671cd532bc3faaca485869e5a8630e 203 ProSitePatterns PS00622 LuxR-type HTH domain signature. 156 183 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS19250 5e671cd532bc3faaca485869e5a8630e 203 SMART SM00421 139 196 1.2E-22 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS19250 5e671cd532bc3faaca485869e5a8630e 203 SUPERFAMILY SSF52172 1 127 1.37E-29 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS19250 5e671cd532bc3faaca485869e5a8630e 203 Gene3D G3DSA:3.40.50.2300 1 143 5.2E-34 T 06-07-2017 SMD11_RS19250 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 3.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS19250 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 3.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS19250 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 3.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS08055 bdf215bf0ce332d511b1b41d0ee052d9 614 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 506 4.8E-11 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS08055 bdf215bf0ce332d511b1b41d0ee052d9 614 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS08055 bdf215bf0ce332d511b1b41d0ee052d9 614 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 285 2.3E-93 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS08055 bdf215bf0ce332d511b1b41d0ee052d9 614 Gene3D G3DSA:3.40.47.10 37 297 1.7E-93 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08055 bdf215bf0ce332d511b1b41d0ee052d9 614 Gene3D G3DSA:3.40.47.10 298 464 3.2E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08055 bdf215bf0ce332d511b1b41d0ee052d9 614 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 409 8.7E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08055 bdf215bf0ce332d511b1b41d0ee052d9 614 Pfam PF08990 Erythronolide synthase docking 4 28 1.2E-8 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 SMD11_RS08055 bdf215bf0ce332d511b1b41d0ee052d9 614 SUPERFAMILY SSF53901 31 405 9.43E-105 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS08055 bdf215bf0ce332d511b1b41d0ee052d9 614 SMART SM00825 Beta-ketoacyl synthase 37 463 3.9E-223 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS09230 a4a96dc2778e3987ca5ffe6aefecdb0d 150 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 97 3.0E-41 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 SMD11_RS09230 a4a96dc2778e3987ca5ffe6aefecdb0d 150 SUPERFAMILY SSF89919 2 113 7.06E-31 T 06-07-2017 IPR023799 Ribosome-binding factor A domain SMD11_RS09230 a4a96dc2778e3987ca5ffe6aefecdb0d 150 Pfam PF02033 Ribosome-binding factor A 6 110 1.2E-25 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 SMD11_RS09230 a4a96dc2778e3987ca5ffe6aefecdb0d 150 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 117 20.339 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 SMD11_RS09230 a4a96dc2778e3987ca5ffe6aefecdb0d 150 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 112 3.1E-22 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 SMD11_RS09230 a4a96dc2778e3987ca5ffe6aefecdb0d 150 ProSitePatterns PS01319 Ribosome-binding factor A signature. 76 97 - T 06-07-2017 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 SMD11_RS09230 a4a96dc2778e3987ca5ffe6aefecdb0d 150 Gene3D G3DSA:3.30.300.20 3 118 7.3E-36 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta SMD11_RS24380 5485d40e0c7dd06a5a7a9f06a4c4de40 301 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 191 198 - T 06-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 SMD11_RS24380 5485d40e0c7dd06a5a7a9f06a4c4de40 301 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 19 293 2.9E-61 T 06-07-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 SMD11_RS24380 5485d40e0c7dd06a5a7a9f06a4c4de40 301 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 82 90 - T 06-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 SMD11_RS24380 5485d40e0c7dd06a5a7a9f06a4c4de40 301 Pfam PF01261 Xylose isomerase-like TIM barrel 36 255 9.6E-32 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS24380 5485d40e0c7dd06a5a7a9f06a4c4de40 301 SMART SM00518 18 296 9.5E-99 T 06-07-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 SMD11_RS24380 5485d40e0c7dd06a5a7a9f06a4c4de40 301 SUPERFAMILY SSF51658 19 296 3.4E-72 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS24380 5485d40e0c7dd06a5a7a9f06a4c4de40 301 Hamap MF_00152 Probable endonuclease 4 [nfo]. 17 296 37.693 T 06-07-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 SMD11_RS24380 5485d40e0c7dd06a5a7a9f06a4c4de40 301 Gene3D G3DSA:3.20.20.150 18 296 9.9E-83 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS24380 5485d40e0c7dd06a5a7a9f06a4c4de40 301 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 231 247 - T 06-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 SMD11_RS32440 712b8864246d8d877bf03d7e7da38c8b 432 Gene3D G3DSA:3.40.50.720 1 157 3.1E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32440 712b8864246d8d877bf03d7e7da38c8b 432 Gene3D G3DSA:3.40.50.720 274 322 3.1E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32440 712b8864246d8d877bf03d7e7da38c8b 432 SUPERFAMILY SSF51905 280 358 6.91E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS32440 712b8864246d8d877bf03d7e7da38c8b 432 SUPERFAMILY SSF51905 1 152 6.91E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS23955 6b73061866b6ebdef7415eb04c34c8be 333 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 49 325 2.2E-22 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS23955 6b73061866b6ebdef7415eb04c34c8be 333 TIGRFAM TIGR03395 sphingomy: sphingomyelin phosphodiesterase 45 330 1.2E-96 T 06-07-2017 IPR017766 Sphingomyelinase C/phospholipase C GO:0005576|GO:0008081 SMD11_RS23955 6b73061866b6ebdef7415eb04c34c8be 333 SUPERFAMILY SSF56219 44 330 8.49E-73 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS23955 6b73061866b6ebdef7415eb04c34c8be 333 Gene3D G3DSA:3.60.10.10 81 329 6.2E-9 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS10995 8a0bb7a08396b691ce5b071724babf75 756 Gene3D G3DSA:3.30.365.10 408 580 1.1E-25 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS10995 8a0bb7a08396b691ce5b071724babf75 756 SUPERFAMILY SSF56003 84 277 3.84E-28 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS10995 8a0bb7a08396b691ce5b071724babf75 756 Gene3D G3DSA:3.30.365.10 89 210 1.0E-31 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS10995 8a0bb7a08396b691ce5b071724babf75 756 Gene3D G3DSA:3.30.365.10 581 746 8.5E-26 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS10995 8a0bb7a08396b691ce5b071724babf75 756 SMART SM01008 244 323 1.1E-14 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS10995 8a0bb7a08396b691ce5b071724babf75 756 Gene3D G3DSA:3.90.1170.50 218 319 8.9E-16 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS10995 8a0bb7a08396b691ce5b071724babf75 756 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 353 587 2.6E-27 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS10995 8a0bb7a08396b691ce5b071724babf75 756 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 89 211 1.0E-14 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS10995 8a0bb7a08396b691ce5b071724babf75 756 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 634 699 6.7E-7 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS10995 8a0bb7a08396b691ce5b071724babf75 756 SUPERFAMILY SSF56003 353 745 1.04E-84 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS10995 8a0bb7a08396b691ce5b071724babf75 756 PIRSF PIRSF036389 22 751 4.2E-176 T 06-07-2017 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related SMD11_RS21230 dffcdadb81fb2512547cab0aa1848be7 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 286 1.2E-68 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS21230 dffcdadb81fb2512547cab0aa1848be7 316 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 298 5.3E-111 T 06-07-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 SMD11_RS21230 dffcdadb81fb2512547cab0aa1848be7 316 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 SMD11_RS21230 dffcdadb81fb2512547cab0aa1848be7 316 Gene3D G3DSA:3.40.50.1100 42 143 8.2E-39 T 06-07-2017 SMD11_RS21230 dffcdadb81fb2512547cab0aa1848be7 316 SUPERFAMILY SSF53686 6 295 6.94E-87 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS21230 dffcdadb81fb2512547cab0aa1848be7 316 Gene3D G3DSA:3.40.50.1100 3 41 1.4E-66 T 06-07-2017 SMD11_RS21230 dffcdadb81fb2512547cab0aa1848be7 316 Gene3D G3DSA:3.40.50.1100 149 302 1.4E-66 T 06-07-2017 SMD11_RS05280 7486d4b048a4ba3027bceec874dda0e6 288 Gene3D G3DSA:1.10.260.40 14 71 3.6E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS05280 7486d4b048a4ba3027bceec874dda0e6 288 SUPERFAMILY SSF47413 12 71 3.94E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS05280 7486d4b048a4ba3027bceec874dda0e6 288 SMART SM00530 20 75 5.6E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS05280 7486d4b048a4ba3027bceec874dda0e6 288 Pfam PF13560 Helix-turn-helix domain 17 77 2.8E-14 T 06-07-2017 SMD11_RS31600 c21019a85c6e76b35b9ce68f1cce90f4 368 Gene3D G3DSA:3.10.150.10 125 245 1.9E-15 T 06-07-2017 SMD11_RS31600 c21019a85c6e76b35b9ce68f1cce90f4 368 SMART SM00422 8 78 9.0E-13 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS31600 c21019a85c6e76b35b9ce68f1cce90f4 368 SUPERFAMILY SSF46955 8 105 6.59E-19 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS31600 c21019a85c6e76b35b9ce68f1cce90f4 368 Gene3D G3DSA:3.10.150.10 256 361 4.8E-7 T 06-07-2017 SMD11_RS31600 c21019a85c6e76b35b9ce68f1cce90f4 368 Pfam PF13411 MerR HTH family regulatory protein 10 76 2.6E-12 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS31600 c21019a85c6e76b35b9ce68f1cce90f4 368 SUPERFAMILY SSF55979 126 243 1.81E-9 T 06-07-2017 SMD11_RS31600 c21019a85c6e76b35b9ce68f1cce90f4 368 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 224 1.2E-9 T 06-07-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS31600 c21019a85c6e76b35b9ce68f1cce90f4 368 Gene3D G3DSA:1.10.1660.10 10 112 3.3E-20 T 06-07-2017 SMD11_RS31600 c21019a85c6e76b35b9ce68f1cce90f4 368 SMART SM00480 38 359 0.008 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS27310 aba413c5d9291fe4080de38366dbac2b 151 SUPERFAMILY SSF52304 9 149 7.59E-52 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS27310 aba413c5d9291fe4080de38366dbac2b 151 PIRSF PIRSF001399 6 150 7.8E-54 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS27310 aba413c5d9291fe4080de38366dbac2b 151 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 14 138 8.0E-39 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS27310 aba413c5d9291fe4080de38366dbac2b 151 Pfam PF01220 Dehydroquinase class II 9 145 9.4E-50 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS27310 aba413c5d9291fe4080de38366dbac2b 151 ProSitePatterns PS01029 Dehydroquinase class II signature. 13 30 - T 06-07-2017 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS27310 aba413c5d9291fe4080de38366dbac2b 151 Gene3D G3DSA:3.40.50.9100 9 149 1.3E-54 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS27310 aba413c5d9291fe4080de38366dbac2b 151 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 151 58.257 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS27310 aba413c5d9291fe4080de38366dbac2b 151 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 9 148 5.4E-52 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS03915 576c082eb968a468fc74f812f1c8a664 261 Gene3D G3DSA:3.90.226.10 5 244 1.3E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS03915 576c082eb968a468fc74f812f1c8a664 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 244 9.8E-38 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS03915 576c082eb968a468fc74f812f1c8a664 261 SUPERFAMILY SSF52096 8 229 1.89E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS03915 576c082eb968a468fc74f812f1c8a664 261 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMD11_RS09810 ad07fff4f6604efa55fb846768863b59 242 SUPERFAMILY SSF55781 66 238 5.1E-35 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS09810 ad07fff4f6604efa55fb846768863b59 242 SMART SM00346 11 97 2.9E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS09810 ad07fff4f6604efa55fb846768863b59 242 Pfam PF09339 IclR helix-turn-helix domain 14 61 3.1E-9 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS09810 ad07fff4f6604efa55fb846768863b59 242 SUPERFAMILY SSF46785 11 79 2.18E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS09810 ad07fff4f6604efa55fb846768863b59 242 Gene3D G3DSA:3.30.450.40 78 238 9.6E-41 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS09810 ad07fff4f6604efa55fb846768863b59 242 Pfam PF01614 Bacterial transcriptional regulator 129 236 3.1E-17 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal SMD11_RS09810 ad07fff4f6604efa55fb846768863b59 242 Gene3D G3DSA:1.10.10.10 7 77 6.6E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28080 d47563ad48634a3b3c1a87f1591ef68b 500 Gene3D G3DSA:3.30.420.40 255 499 2.0E-96 T 06-07-2017 SMD11_RS28080 d47563ad48634a3b3c1a87f1591ef68b 500 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 261 451 1.5E-62 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMD11_RS28080 d47563ad48634a3b3c1a87f1591ef68b 500 Gene3D G3DSA:3.30.420.40 2 253 7.4E-100 T 06-07-2017 SMD11_RS28080 d47563ad48634a3b3c1a87f1591ef68b 500 PIRSF PIRSF000538 3 500 1.5E-159 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD11_RS28080 d47563ad48634a3b3c1a87f1591ef68b 500 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD11_RS28080 d47563ad48634a3b3c1a87f1591ef68b 500 Hamap MF_00186 Glycerol kinase [glpK]. 3 498 54.445 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMD11_RS28080 d47563ad48634a3b3c1a87f1591ef68b 500 SUPERFAMILY SSF53067 5 255 2.85E-87 T 06-07-2017 SMD11_RS28080 d47563ad48634a3b3c1a87f1591ef68b 500 SUPERFAMILY SSF53067 255 498 3.89E-79 T 06-07-2017 SMD11_RS28080 d47563ad48634a3b3c1a87f1591ef68b 500 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 252 4.9E-73 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMD11_RS28080 d47563ad48634a3b3c1a87f1591ef68b 500 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 363 383 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD11_RS28080 d47563ad48634a3b3c1a87f1591ef68b 500 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 497 5.8E-213 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 PRINTS PR00385 P450 superfamily signature 241 258 2.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 PRINTS PR00385 P450 superfamily signature 362 373 2.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 PRINTS PR00385 P450 superfamily signature 353 362 2.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 PRINTS PR00385 P450 superfamily signature 277 288 2.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 PRINTS PR00359 B-class P450 signature 157 172 6.0E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 PRINTS PR00359 B-class P450 signature 277 288 6.0E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 PRINTS PR00359 B-class P450 signature 196 218 6.0E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 PRINTS PR00359 B-class P450 signature 353 362 6.0E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 PRINTS PR00359 B-class P450 signature 324 339 6.0E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 PRINTS PR00359 B-class P450 signature 140 156 6.0E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 PRINTS PR00359 B-class P450 signature 90 101 6.0E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 PRINTS PR00359 B-class P450 signature 362 373 6.0E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 PRINTS PR00359 B-class P450 signature 296 323 6.0E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 Gene3D G3DSA:1.10.630.10 5 413 2.4E-120 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 SUPERFAMILY SSF48264 6 413 3.14E-92 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 355 364 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS30005 17de70091aad8de9875022e28c5eb29c 414 Pfam PF00067 Cytochrome P450 277 381 7.9E-20 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS11540 816262fc77bb785eefb486d9e7cf26b2 590 SUPERFAMILY SSF51219 392 589 1.52E-33 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMD11_RS11540 816262fc77bb785eefb486d9e7cf26b2 590 Pfam PF02342 TerD domain 1 170 5.1E-35 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS11540 816262fc77bb785eefb486d9e7cf26b2 590 Gene3D G3DSA:2.60.60.30 30 168 8.3E-27 T 06-07-2017 SMD11_RS11540 816262fc77bb785eefb486d9e7cf26b2 590 PRINTS PR01217 Proline rich extensin signature 219 235 1.2E-10 T 06-07-2017 SMD11_RS11540 816262fc77bb785eefb486d9e7cf26b2 590 PRINTS PR01217 Proline rich extensin signature 287 312 1.2E-10 T 06-07-2017 SMD11_RS11540 816262fc77bb785eefb486d9e7cf26b2 590 PRINTS PR01217 Proline rich extensin signature 240 257 1.2E-10 T 06-07-2017 SMD11_RS11540 816262fc77bb785eefb486d9e7cf26b2 590 PRINTS PR01217 Proline rich extensin signature 195 216 1.2E-10 T 06-07-2017 SMD11_RS11540 816262fc77bb785eefb486d9e7cf26b2 590 Gene3D G3DSA:3.60.160.10 395 588 7.2E-28 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 SMD11_RS11540 816262fc77bb785eefb486d9e7cf26b2 590 Pfam PF01987 Mitochondrial biogenesis AIM24 395 587 4.7E-23 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 SMD11_RS20790 3dd11419a93ff85977508f98c45481dd 615 SUPERFAMILY SSF63829 371 597 9.48E-9 T 06-07-2017 SMD11_RS20790 3dd11419a93ff85977508f98c45481dd 615 Pfam PF10646 Sporulation and spore germination 216 316 4.1E-7 T 06-07-2017 IPR019606 GerMN domain SMD11_RS20790 3dd11419a93ff85977508f98c45481dd 615 Gene3D G3DSA:2.120.10.30 374 595 1.8E-7 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS20790 3dd11419a93ff85977508f98c45481dd 615 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 351 614 2.8E-43 T 06-07-2017 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal SMD11_RS20790 3dd11419a93ff85977508f98c45481dd 615 SMART SM00909 229 322 1.5E-8 T 06-07-2017 IPR019606 GerMN domain SMD11_RS26370 a433349b1fe51815872988227abc5de6 196 Pfam PF11290 Protein of unknown function (DUF3090) 7 186 2.2E-66 T 06-07-2017 IPR021441 Protein of unknown function DUF3090 SMD11_RS26370 a433349b1fe51815872988227abc5de6 196 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 190 8.3E-76 T 06-07-2017 IPR021441 Protein of unknown function DUF3090 SMD11_RS33105 6e074072bc2d5978d6a3e6d1f6d3d4d6 711 SUPERFAMILY SSF52540 439 681 1.21E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS33105 6e074072bc2d5978d6a3e6d1f6d3d4d6 711 SMART SM00382 483 611 1.9E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS33105 6e074072bc2d5978d6a3e6d1f6d3d4d6 711 Gene3D G3DSA:3.40.50.300 441 627 3.1E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS33105 6e074072bc2d5978d6a3e6d1f6d3d4d6 711 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 488 612 3.6E-24 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS25250 9ef3e8fe1a916515eb295f1c59aeaeed 107 SUPERFAMILY SSF103481 6 105 9.29E-20 T 06-07-2017 SMD11_RS25250 9ef3e8fe1a916515eb295f1c59aeaeed 107 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.8E-26 T 06-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 SMD11_RS28965 81f36b8708e3af5e9d50cd4f6db0c66e 540 Gene3D G3DSA:3.30.870.10 102 265 9.6E-24 T 06-07-2017 SMD11_RS28965 81f36b8708e3af5e9d50cd4f6db0c66e 540 SUPERFAMILY SSF56024 300 536 5.02E-38 T 06-07-2017 SMD11_RS28965 81f36b8708e3af5e9d50cd4f6db0c66e 540 SUPERFAMILY SSF56024 40 281 1.41E-34 T 06-07-2017 SMD11_RS28965 81f36b8708e3af5e9d50cd4f6db0c66e 540 Gene3D G3DSA:3.30.870.10 286 538 3.5E-107 T 06-07-2017 SMD11_RS28965 81f36b8708e3af5e9d50cd4f6db0c66e 540 SMART SM00155 196 223 0.02 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 SMD11_RS28965 81f36b8708e3af5e9d50cd4f6db0c66e 540 SMART SM00155 469 496 8.1E-4 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 SMD11_RS28965 81f36b8708e3af5e9d50cd4f6db0c66e 540 Pfam PF13091 PLD-like domain 107 222 3.7E-7 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 SMD11_RS28965 81f36b8708e3af5e9d50cd4f6db0c66e 540 Pfam PF13091 PLD-like domain 356 515 2.4E-8 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 SMD11_RS33650 6575979aa7c8c0cc45ad53229c3ed710 384 SUPERFAMILY SSF51905 7 173 4.49E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS33650 6575979aa7c8c0cc45ad53229c3ed710 384 SUPERFAMILY SSF51905 279 357 4.49E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS33650 6575979aa7c8c0cc45ad53229c3ed710 384 Pfam PF01494 FAD binding domain 7 171 1.6E-11 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS33650 6575979aa7c8c0cc45ad53229c3ed710 384 Pfam PF01494 FAD binding domain 298 352 3.2E-5 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS33650 6575979aa7c8c0cc45ad53229c3ed710 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 1.5E-13 T 06-07-2017 SMD11_RS33650 6575979aa7c8c0cc45ad53229c3ed710 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 309 1.5E-13 T 06-07-2017 SMD11_RS33650 6575979aa7c8c0cc45ad53229c3ed710 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.5E-13 T 06-07-2017 SMD11_RS33650 6575979aa7c8c0cc45ad53229c3ed710 384 Gene3D G3DSA:3.50.50.60 6 178 2.9E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS33650 6575979aa7c8c0cc45ad53229c3ed710 384 Gene3D G3DSA:3.50.50.60 280 356 2.9E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31150 77cc67ad5f0b407087bc61d2a4a209ce 315 SUPERFAMILY SSF53697 126 310 1.6E-12 T 06-07-2017 SMD11_RS31150 77cc67ad5f0b407087bc61d2a4a209ce 315 Pfam PF01418 Helix-turn-helix domain, rpiR family 45 104 1.7E-15 T 06-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SMD11_RS31150 77cc67ad5f0b407087bc61d2a4a209ce 315 Pfam PF01380 SIS domain 165 284 5.9E-8 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 SMD11_RS31150 77cc67ad5f0b407087bc61d2a4a209ce 315 Gene3D G3DSA:3.40.50.10490 140 286 5.0E-11 T 06-07-2017 SMD11_RS31150 77cc67ad5f0b407087bc61d2a4a209ce 315 Gene3D G3DSA:3.40.50.10490 96 107 5.0E-11 T 06-07-2017 SMD11_RS31150 77cc67ad5f0b407087bc61d2a4a209ce 315 Gene3D G3DSA:1.10.10.10 46 95 2.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS31150 77cc67ad5f0b407087bc61d2a4a209ce 315 SUPERFAMILY SSF46689 46 105 4.66E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS25240 60baeab36231d7e587b7e51dcf6af0aa 120 Pfam PF01883 Domain of unknown function DUF59 22 82 1.0E-18 T 06-07-2017 IPR002744 Domain of unknown function DUF59 SMD11_RS25240 60baeab36231d7e587b7e51dcf6af0aa 120 SUPERFAMILY SSF117916 20 114 1.96E-27 T 06-07-2017 SMD11_RS07720 e668bc85d54486290dfc9ef6a72659a4 192 TIGRFAM TIGR00277 HDIG: HDIG domain 27 96 2.6E-8 T 06-07-2017 IPR006675 HDIG domain SMD11_RS07720 e668bc85d54486290dfc9ef6a72659a4 192 SMART SM00471 21 166 1.1E-5 T 06-07-2017 IPR003607 HD/PDEase domain SMD11_RS07720 e668bc85d54486290dfc9ef6a72659a4 192 SUPERFAMILY SSF109604 134 155 9.87E-16 T 06-07-2017 SMD11_RS07720 e668bc85d54486290dfc9ef6a72659a4 192 SUPERFAMILY SSF109604 17 98 9.87E-16 T 06-07-2017 SMD11_RS07720 e668bc85d54486290dfc9ef6a72659a4 192 Pfam PF01966 HD domain 25 154 4.4E-13 T 06-07-2017 IPR006674 HD domain SMD11_RS07720 e668bc85d54486290dfc9ef6a72659a4 192 Gene3D G3DSA:1.10.3210.10 14 112 6.8E-14 T 06-07-2017 IPR006674 HD domain SMD11_RS25330 d9e445671a21f83f14da126239d41e93 343 Gene3D G3DSA:3.40.50.150 97 343 4.8E-55 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS25330 d9e445671a21f83f14da126239d41e93 343 Pfam PF16864 Dimerisation domain 17 96 5.1E-17 T 06-07-2017 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain SMD11_RS25330 d9e445671a21f83f14da126239d41e93 343 SUPERFAMILY SSF53335 98 341 1.52E-48 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS25330 d9e445671a21f83f14da126239d41e93 343 SUPERFAMILY SSF46785 15 90 8.53E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS25330 d9e445671a21f83f14da126239d41e93 343 Gene3D G3DSA:1.10.10.10 14 90 2.0E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS25330 d9e445671a21f83f14da126239d41e93 343 Pfam PF00891 O-methyltransferase 106 328 3.4E-38 T 06-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 SMD11_RS25330 d9e445671a21f83f14da126239d41e93 343 PIRSF PIRSF005739 1 343 3.4E-31 T 06-07-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 SMD11_RS16915 f5ec9335fbfaa0965f90a4079fa08425 376 SUPERFAMILY SSF55979 126 247 1.13E-17 T 06-07-2017 SMD11_RS16915 f5ec9335fbfaa0965f90a4079fa08425 376 SUPERFAMILY SSF55979 2 119 1.75E-24 T 06-07-2017 SMD11_RS16915 f5ec9335fbfaa0965f90a4079fa08425 376 Gene3D G3DSA:3.10.150.10 252 374 1.3E-37 T 06-07-2017 SMD11_RS16915 f5ec9335fbfaa0965f90a4079fa08425 376 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 374 2.5E-89 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS16915 f5ec9335fbfaa0965f90a4079fa08425 376 Pfam PF02767 DNA polymerase III beta subunit, central domain 127 246 2.3E-31 T 06-07-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS16915 f5ec9335fbfaa0965f90a4079fa08425 376 SMART SM00480 17 370 8.6E-140 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS16915 f5ec9335fbfaa0965f90a4079fa08425 376 SUPERFAMILY SSF55979 249 374 2.88E-29 T 06-07-2017 SMD11_RS16915 f5ec9335fbfaa0965f90a4079fa08425 376 PIRSF PIRSF000804 1 375 3.3E-94 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS16915 f5ec9335fbfaa0965f90a4079fa08425 376 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 248 373 2.8E-35 T 06-07-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS16915 f5ec9335fbfaa0965f90a4079fa08425 376 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 118 1.5E-38 T 06-07-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS16915 f5ec9335fbfaa0965f90a4079fa08425 376 Gene3D G3DSA:3.10.150.10 2 120 1.1E-31 T 06-07-2017 SMD11_RS16915 f5ec9335fbfaa0965f90a4079fa08425 376 Gene3D G3DSA:3.10.150.10 126 250 1.7E-28 T 06-07-2017 SMD11_RS03830 c41e229f2cb58afdd733982d0afbd695 385 PIRSF PIRSF000429 1 385 1.9E-119 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS03830 c41e229f2cb58afdd733982d0afbd695 385 Pfam PF02803 Thiolase, C-terminal domain 263 384 8.4E-44 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD11_RS03830 c41e229f2cb58afdd733982d0afbd695 385 Gene3D G3DSA:3.40.47.10 160 195 6.9E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS03830 c41e229f2cb58afdd733982d0afbd695 385 Gene3D G3DSA:3.40.47.10 269 384 6.9E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS03830 c41e229f2cb58afdd733982d0afbd695 385 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 383 1.8E-120 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS03830 c41e229f2cb58afdd733982d0afbd695 385 SUPERFAMILY SSF53901 3 262 3.26E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS03830 c41e229f2cb58afdd733982d0afbd695 385 Pfam PF00108 Thiolase, N-terminal domain 5 253 4.9E-55 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD11_RS03830 c41e229f2cb58afdd733982d0afbd695 385 ProSitePatterns PS00737 Thiolases signature 2. 331 347 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMD11_RS03830 c41e229f2cb58afdd733982d0afbd695 385 Gene3D G3DSA:3.40.47.10 4 124 1.0E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS03830 c41e229f2cb58afdd733982d0afbd695 385 Gene3D G3DSA:3.40.47.10 196 268 1.0E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS03830 c41e229f2cb58afdd733982d0afbd695 385 SUPERFAMILY SSF53901 263 384 1.87E-42 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29810 a78a15ac2a5d06cf7203e47377342ae1 88 ProSitePatterns PS00012 Phosphopantetheine attachment site. 37 52 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS29810 a78a15ac2a5d06cf7203e47377342ae1 88 SUPERFAMILY SSF47336 4 85 4.97E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29810 a78a15ac2a5d06cf7203e47377342ae1 88 Pfam PF00550 Phosphopantetheine attachment site 23 77 5.1E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29810 a78a15ac2a5d06cf7203e47377342ae1 88 Gene3D G3DSA:1.10.1200.10 3 84 2.9E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29390 0a1378745ca0e05bac65b1f9e0132387 118 Pfam PF03061 Thioesterase superfamily 28 102 1.8E-13 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 SMD11_RS29390 0a1378745ca0e05bac65b1f9e0132387 118 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 2 111 1.1E-26 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 SMD11_RS29390 0a1378745ca0e05bac65b1f9e0132387 118 SUPERFAMILY SSF54637 1 117 1.54E-24 T 06-07-2017 IPR029069 HotDog domain SMD11_RS29390 0a1378745ca0e05bac65b1f9e0132387 118 Gene3D G3DSA:3.10.129.10 1 113 1.6E-37 T 06-07-2017 IPR029069 HotDog domain SMD11_RS13530 4f19bd76453ee59029b93932020daabb 127 Pfam PF13466 STAS domain 16 80 3.0E-12 T 06-07-2017 IPR002645 STAS domain SMD11_RS13530 4f19bd76453ee59029b93932020daabb 127 SUPERFAMILY SSF52091 8 115 3.34E-21 T 06-07-2017 IPR002645 STAS domain SMD11_RS13530 4f19bd76453ee59029b93932020daabb 127 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 112 4.2E-18 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMD11_RS13530 4f19bd76453ee59029b93932020daabb 127 Gene3D G3DSA:3.30.750.24 5 117 3.2E-36 T 06-07-2017 IPR002645 STAS domain SMD11_RS13240 01bd1f401b1a1fe3ccb7dccefc075f37 294 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 SMD11_RS13240 01bd1f401b1a1fe3ccb7dccefc075f37 294 SMART SM00881 4 104 1.3E-30 T 06-07-2017 IPR003781 CoA-binding GO:0048037 SMD11_RS13240 01bd1f401b1a1fe3ccb7dccefc075f37 294 PIRSF PIRSF001553 1 294 4.2E-114 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 SMD11_RS13240 01bd1f401b1a1fe3ccb7dccefc075f37 294 Pfam PF00549 CoA-ligase 158 275 1.2E-13 T 06-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS13240 01bd1f401b1a1fe3ccb7dccefc075f37 294 SUPERFAMILY SSF51735 1 128 3.29E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS13240 01bd1f401b1a1fe3ccb7dccefc075f37 294 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 290 1.2E-125 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 SMD11_RS13240 01bd1f401b1a1fe3ccb7dccefc075f37 294 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 1.6E-34 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 SMD11_RS13240 01bd1f401b1a1fe3ccb7dccefc075f37 294 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 1.6E-34 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 SMD11_RS13240 01bd1f401b1a1fe3ccb7dccefc075f37 294 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 1.6E-34 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 SMD11_RS13240 01bd1f401b1a1fe3ccb7dccefc075f37 294 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 1.6E-34 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 SMD11_RS13240 01bd1f401b1a1fe3ccb7dccefc075f37 294 Gene3D G3DSA:3.40.50.261 126 290 2.0E-65 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS13240 01bd1f401b1a1fe3ccb7dccefc075f37 294 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 06-07-2017 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site SMD11_RS13240 01bd1f401b1a1fe3ccb7dccefc075f37 294 SUPERFAMILY SSF52210 129 290 6.15E-46 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS13240 01bd1f401b1a1fe3ccb7dccefc075f37 294 Gene3D G3DSA:3.40.50.720 3 125 1.7E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS13240 01bd1f401b1a1fe3ccb7dccefc075f37 294 Pfam PF02629 CoA binding domain 6 103 5.7E-26 T 06-07-2017 IPR003781 CoA-binding GO:0048037 SMD11_RS06775 caab6ca4f5b83a48d75e2b6752edb47b 412 Gene3D G3DSA:1.10.540.10 4 109 3.7E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS06775 caab6ca4f5b83a48d75e2b6752edb47b 412 Gene3D G3DSA:2.40.110.10 137 206 6.9E-14 T 06-07-2017 SMD11_RS06775 caab6ca4f5b83a48d75e2b6752edb47b 412 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 236 371 1.9E-11 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain SMD11_RS06775 caab6ca4f5b83a48d75e2b6752edb47b 412 SUPERFAMILY SSF56645 20 212 8.64E-37 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS06775 caab6ca4f5b83a48d75e2b6752edb47b 412 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 21 115 4.4E-7 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS06775 caab6ca4f5b83a48d75e2b6752edb47b 412 Gene3D G3DSA:1.20.140.10 207 392 1.3E-40 T 06-07-2017 SMD11_RS06775 caab6ca4f5b83a48d75e2b6752edb47b 412 SUPERFAMILY SSF47203 228 372 1.73E-9 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS10345 f7906cd5221bb639068d1293ef00a265 391 Pfam PF13205 Bacterial Ig-like domain 126 219 3.2E-7 T 06-07-2017 IPR032812 SbsA, Ig-like domain SMD11_RS10345 f7906cd5221bb639068d1293ef00a265 391 SUPERFAMILY SSF141523 227 359 3.53E-22 T 06-07-2017 SMD11_RS10345 f7906cd5221bb639068d1293ef00a265 391 Gene3D G3DSA:2.40.440.10 227 360 3.5E-19 T 06-07-2017 SMD11_RS10345 f7906cd5221bb639068d1293ef00a265 391 Pfam PF03734 L,D-transpeptidase catalytic domain 225 359 1.1E-12 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMD11_RS27590 e070c49be36d214f54416726f8d46417 90 Gene3D G3DSA:2.80.10.50 46 86 2.3E-7 T 06-07-2017 SMD11_RS27590 e070c49be36d214f54416726f8d46417 90 SUPERFAMILY SSF50370 46 88 2.03E-9 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS23105 1b5156b7c7261a8d0c2aa196bc10667b 142 SUPERFAMILY SSF46785 5 138 4.46E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23105 1b5156b7c7261a8d0c2aa196bc10667b 142 Gene3D G3DSA:1.10.10.10 2 138 2.4E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23105 1b5156b7c7261a8d0c2aa196bc10667b 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.1E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS23105 1b5156b7c7261a8d0c2aa196bc10667b 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 1.1E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS23105 1b5156b7c7261a8d0c2aa196bc10667b 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 1.1E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS23105 1b5156b7c7261a8d0c2aa196bc10667b 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.1E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS23105 1b5156b7c7261a8d0c2aa196bc10667b 142 ProSitePatterns PS01117 MarR-type HTH domain signature. 67 101 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site SMD11_RS23105 1b5156b7c7261a8d0c2aa196bc10667b 142 Pfam PF12802 MarR family 35 91 9.6E-15 T 06-07-2017 SMD11_RS23105 1b5156b7c7261a8d0c2aa196bc10667b 142 SMART SM00347 29 127 4.1E-20 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS01925 1c238951ee324308cdbd9d5459bcde86 124 Pfam PF12840 Helix-turn-helix domain 21 74 3.2E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01925 1c238951ee324308cdbd9d5459bcde86 124 SUPERFAMILY SSF46785 10 97 3.1E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01925 1c238951ee324308cdbd9d5459bcde86 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 6.8E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS01925 1c238951ee324308cdbd9d5459bcde86 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 6.8E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS01925 1c238951ee324308cdbd9d5459bcde86 124 SMART SM00418 21 98 1.6E-15 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS01925 1c238951ee324308cdbd9d5459bcde86 124 Gene3D G3DSA:1.10.10.10 6 97 1.4E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14200 029f0c0278379b0a4bbe586ea1b12515 253 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 7 251 1.9E-111 T 06-07-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 SMD11_RS14200 029f0c0278379b0a4bbe586ea1b12515 253 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 5 234 42.097 T 06-07-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 SMD11_RS14200 029f0c0278379b0a4bbe586ea1b12515 253 Gene3D G3DSA:3.40.50.1240 5 253 2.3E-87 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS14200 029f0c0278379b0a4bbe586ea1b12515 253 SUPERFAMILY SSF53254 6 227 6.42E-70 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS14200 029f0c0278379b0a4bbe586ea1b12515 253 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 135 2.4E-26 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS14200 029f0c0278379b0a4bbe586ea1b12515 253 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 10 19 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 SMD11_RS14200 029f0c0278379b0a4bbe586ea1b12515 253 SMART SM00855 7 193 3.1E-22 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS24000 9c7645d6091291a763caac52105d270b 177 Gene3D G3DSA:3.90.79.10 35 154 8.4E-27 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS24000 9c7645d6091291a763caac52105d270b 177 ProSitePatterns PS00893 Nudix box signature. 69 90 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD11_RS24000 9c7645d6091291a763caac52105d270b 177 Pfam PF00293 NUDIX domain 35 161 5.6E-20 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS24000 9c7645d6091291a763caac52105d270b 177 PRINTS PR00502 NUDIX hydrolase family signature 78 93 6.9E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS24000 9c7645d6091291a763caac52105d270b 177 PRINTS PR00502 NUDIX hydrolase family signature 64 78 6.9E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS24000 9c7645d6091291a763caac52105d270b 177 SUPERFAMILY SSF55811 32 156 5.55E-26 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS03310 e841969c3eac12d0c25eebf6cd302472 82 Gene3D G3DSA:1.10.1200.10 2 76 1.2E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS03310 e841969c3eac12d0c25eebf6cd302472 82 Pfam PF00550 Phosphopantetheine attachment site 24 74 8.0E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS03310 e841969c3eac12d0c25eebf6cd302472 82 SUPERFAMILY SSF47336 3 76 2.75E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS03310 e841969c3eac12d0c25eebf6cd302472 82 ProSitePatterns PS00012 Phosphopantetheine attachment site. 33 48 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS21745 a307feb5985fa4491744b244175a9dac 208 Gene3D G3DSA:1.10.10.60 15 65 7.1E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS21745 a307feb5985fa4491744b244175a9dac 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 3.9E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS21745 a307feb5985fa4491744b244175a9dac 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 3.9E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS21745 a307feb5985fa4491744b244175a9dac 208 SUPERFAMILY SSF46689 9 76 9.98E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS21745 a307feb5985fa4491744b244175a9dac 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 4.6E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS21745 a307feb5985fa4491744b244175a9dac 208 SUPERFAMILY SSF48498 93 173 8.15E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS21745 a307feb5985fa4491744b244175a9dac 208 Gene3D G3DSA:1.10.357.10 66 199 2.0E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS11870 6baeb091c1bc23ce23adac88f494c2af 359 Pfam PF07687 Peptidase dimerisation domain 170 268 2.2E-11 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS11870 6baeb091c1bc23ce23adac88f494c2af 359 Gene3D G3DSA:3.40.630.10 280 353 8.9E-47 T 06-07-2017 SMD11_RS11870 6baeb091c1bc23ce23adac88f494c2af 359 Gene3D G3DSA:3.40.630.10 12 170 8.9E-47 T 06-07-2017 SMD11_RS11870 6baeb091c1bc23ce23adac88f494c2af 359 SUPERFAMILY SSF55031 170 271 4.19E-18 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS11870 6baeb091c1bc23ce23adac88f494c2af 359 Pfam PF01546 Peptidase family M20/M25/M40 69 352 6.2E-22 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD11_RS11870 6baeb091c1bc23ce23adac88f494c2af 359 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 11 358 3.5E-158 T 06-07-2017 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 SMD11_RS11870 6baeb091c1bc23ce23adac88f494c2af 359 SUPERFAMILY SSF53187 279 358 2.43E-42 T 06-07-2017 SMD11_RS11870 6baeb091c1bc23ce23adac88f494c2af 359 SUPERFAMILY SSF53187 14 182 2.43E-42 T 06-07-2017 SMD11_RS11870 6baeb091c1bc23ce23adac88f494c2af 359 Gene3D G3DSA:3.30.70.360 171 270 2.1E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS17260 7dfca1844d02a65d4cf37cc736b9e217 224 Gene3D G3DSA:1.20.120.530 84 217 5.1E-31 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS17260 7dfca1844d02a65d4cf37cc736b9e217 224 SUPERFAMILY SSF46785 14 84 8.54E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17260 7dfca1844d02a65d4cf37cc736b9e217 224 SMART SM00345 22 80 2.4E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS17260 7dfca1844d02a65d4cf37cc736b9e217 224 Gene3D G3DSA:1.10.10.10 13 80 1.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17260 7dfca1844d02a65d4cf37cc736b9e217 224 Pfam PF07729 FCD domain 90 212 1.7E-23 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS17260 7dfca1844d02a65d4cf37cc736b9e217 224 SUPERFAMILY SSF48008 86 217 1.26E-29 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS17260 7dfca1844d02a65d4cf37cc736b9e217 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 80 1.0E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS17260 7dfca1844d02a65d4cf37cc736b9e217 224 SMART SM00895 90 214 1.1E-18 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS17260 7dfca1844d02a65d4cf37cc736b9e217 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 3.1E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS17260 7dfca1844d02a65d4cf37cc736b9e217 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 3.1E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS14720 ec943b6e67d0c7e40c9581730736917b 545 Gene3D G3DSA:2.60.40.360 441 509 8.5E-4 T 06-07-2017 IPR008962 PapD-like SMD11_RS13075 389e6f97f28259565ff2fdb894098650 255 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 28 247 1.0E-79 T 06-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS13075 389e6f97f28259565ff2fdb894098650 255 Gene3D G3DSA:3.10.20.30 20 125 3.3E-39 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS13075 389e6f97f28259565ff2fdb894098650 255 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 25 130 1.4E-35 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS13075 389e6f97f28259565ff2fdb894098650 255 Gene3D G3DSA:1.10.1060.10 126 253 4.9E-40 T 06-07-2017 SMD11_RS13075 389e6f97f28259565ff2fdb894098650 255 SUPERFAMILY SSF54292 21 125 2.59E-29 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS13075 389e6f97f28259565ff2fdb894098650 255 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 167 178 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD11_RS13075 389e6f97f28259565ff2fdb894098650 255 SUPERFAMILY SSF46548 126 251 6.63E-33 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 SMD11_RS13075 389e6f97f28259565ff2fdb894098650 255 Pfam PF13183 4Fe-4S dicluster domain 165 237 7.6E-12 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD11_RS29340 dbcb64b41f32371b3c8fc5c9bf2cd892 683 SUPERFAMILY SSF55486 201 324 1.87E-6 T 06-07-2017 SMD11_RS19830 040b4fdf8148911aa456138bbda2e9b8 425 Gene3D G3DSA:1.20.1250.20 228 401 6.3E-17 T 06-07-2017 SMD11_RS19830 040b4fdf8148911aa456138bbda2e9b8 425 Gene3D G3DSA:1.20.1250.20 22 206 2.6E-9 T 06-07-2017 SMD11_RS19830 040b4fdf8148911aa456138bbda2e9b8 425 Pfam PF07690 Major Facilitator Superfamily 38 307 1.1E-17 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS19830 040b4fdf8148911aa456138bbda2e9b8 425 SUPERFAMILY SSF103473 15 403 7.46E-34 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS01835 4524c9b7e9c2438138a74c43bda866fe 376 Gene3D G3DSA:3.40.190.10 169 282 1.1E-14 T 06-07-2017 SMD11_RS01835 4524c9b7e9c2438138a74c43bda866fe 376 Gene3D G3DSA:3.40.190.10 283 323 7.3E-27 T 06-07-2017 SMD11_RS01835 4524c9b7e9c2438138a74c43bda866fe 376 Gene3D G3DSA:3.40.190.10 16 154 7.3E-27 T 06-07-2017 SMD11_RS01835 4524c9b7e9c2438138a74c43bda866fe 376 Pfam PF13343 Bacterial extracellular solute-binding protein 109 298 6.9E-13 T 06-07-2017 SMD11_RS01835 4524c9b7e9c2438138a74c43bda866fe 376 SUPERFAMILY SSF53850 51 329 5.93E-37 T 06-07-2017 SMD11_RS07710 ba0e7eb6cb2e0a4815fcbc2b2d91b7be 256 Gene3D G3DSA:1.10.260.40 3 63 4.3E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS07710 ba0e7eb6cb2e0a4815fcbc2b2d91b7be 256 SUPERFAMILY SSF56024 92 186 9.42E-5 T 06-07-2017 SMD11_RS07710 ba0e7eb6cb2e0a4815fcbc2b2d91b7be 256 Gene3D G3DSA:3.30.870.10 92 160 1.8E-4 T 06-07-2017 SMD11_RS07710 ba0e7eb6cb2e0a4815fcbc2b2d91b7be 256 SUPERFAMILY SSF47413 3 63 3.83E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS15980 5e5714124ca9fe809a55d7a0bc4fea54 256 Gene3D G3DSA:3.40.50.720 1 253 2.0E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS15980 5e5714124ca9fe809a55d7a0bc4fea54 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS15980 5e5714124ca9fe809a55d7a0bc4fea54 256 SUPERFAMILY SSF51735 2 254 2.89E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS15980 5e5714124ca9fe809a55d7a0bc4fea54 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.9E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS15980 5e5714124ca9fe809a55d7a0bc4fea54 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.9E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS15980 5e5714124ca9fe809a55d7a0bc4fea54 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.9E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS15980 5e5714124ca9fe809a55d7a0bc4fea54 256 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 6 255 5.6E-107 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS15980 5e5714124ca9fe809a55d7a0bc4fea54 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 232 251 7.3E-54 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS15980 5e5714124ca9fe809a55d7a0bc4fea54 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 167 190 7.3E-54 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS15980 5e5714124ca9fe809a55d7a0bc4fea54 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 82 99 7.3E-54 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS15980 5e5714124ca9fe809a55d7a0bc4fea54 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 206 225 7.3E-54 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS15980 5e5714124ca9fe809a55d7a0bc4fea54 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 10 27 7.3E-54 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS15980 5e5714124ca9fe809a55d7a0bc4fea54 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 102 122 7.3E-54 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS15980 5e5714124ca9fe809a55d7a0bc4fea54 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 186 4.4E-5 T 06-07-2017 SMD11_RS15980 5e5714124ca9fe809a55d7a0bc4fea54 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 253 8.7E-62 T 06-07-2017 SMD11_RS21340 4fdcba932966819fab76679383c96dec 735 Pfam PF03176 MMPL family 419 711 6.6E-53 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 SMD11_RS21340 4fdcba932966819fab76679383c96dec 735 Pfam PF03176 MMPL family 46 389 2.7E-49 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 SMD11_RS21340 4fdcba932966819fab76679383c96dec 735 Gene3D G3DSA:1.20.1640.10 510 712 1.1E-32 T 06-07-2017 SMD11_RS21340 4fdcba932966819fab76679383c96dec 735 Gene3D G3DSA:1.20.1640.10 156 365 8.1E-28 T 06-07-2017 SMD11_RS21340 4fdcba932966819fab76679383c96dec 735 SUPERFAMILY SSF82866 158 363 3.27E-27 T 06-07-2017 SMD11_RS21340 4fdcba932966819fab76679383c96dec 735 SUPERFAMILY SSF82866 487 711 8.63E-33 T 06-07-2017 SMD11_RS01415 0adb75e61a529949957cb8ca81ee83b9 276 SUPERFAMILY SSF53335 123 264 1.35E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS01415 0adb75e61a529949957cb8ca81ee83b9 276 Gene3D G3DSA:3.40.50.150 124 238 2.1E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS01415 0adb75e61a529949957cb8ca81ee83b9 276 Pfam PF08241 Methyltransferase domain 136 231 3.2E-13 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 Gene3D G3DSA:1.10.630.10 9 398 2.3E-110 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 340 349 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 Pfam PF00067 Cytochrome P450 218 368 6.0E-24 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 PRINTS PR00359 B-class P450 signature 156 171 8.0E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 PRINTS PR00359 B-class P450 signature 271 282 8.0E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 PRINTS PR00359 B-class P450 signature 139 155 8.0E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 PRINTS PR00359 B-class P450 signature 289 316 8.0E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 PRINTS PR00359 B-class P450 signature 347 358 8.0E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 PRINTS PR00359 B-class P450 signature 193 215 8.0E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 PRINTS PR00359 B-class P450 signature 317 332 8.0E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 PRINTS PR00359 B-class P450 signature 338 347 8.0E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 PRINTS PR00359 B-class P450 signature 92 103 8.0E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 PRINTS PR00385 P450 superfamily signature 347 358 7.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 PRINTS PR00385 P450 superfamily signature 236 253 7.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 PRINTS PR00385 P450 superfamily signature 271 282 7.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 PRINTS PR00385 P450 superfamily signature 338 347 7.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS28910 e62d6e1d9eea4b60909441c35f357f45 398 SUPERFAMILY SSF48264 12 398 7.6E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS08645 0a0acd2c7d236deb8f219bf32a5cab11 818 SUPERFAMILY SSF101904 513 780 1.7E-44 T 06-07-2017 SMD11_RS08645 0a0acd2c7d236deb8f219bf32a5cab11 818 Gene3D G3DSA:2.120.10.90 513 774 1.0E-42 T 06-07-2017 SMD11_RS08645 0a0acd2c7d236deb8f219bf32a5cab11 818 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 42 478 5.3E-148 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08645 0a0acd2c7d236deb8f219bf32a5cab11 818 Gene3D G3DSA:3.90.199.10 345 410 5.2E-111 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08645 0a0acd2c7d236deb8f219bf32a5cab11 818 Gene3D G3DSA:3.90.199.10 41 246 5.2E-111 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS08645 0a0acd2c7d236deb8f219bf32a5cab11 818 SUPERFAMILY SSF56719 41 498 1.57E-164 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SMD11_RS08645 0a0acd2c7d236deb8f219bf32a5cab11 818 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 670 715 1.2E-6 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD11_RS08645 0a0acd2c7d236deb8f219bf32a5cab11 818 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 741 769 0.027 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SMD11_RS08645 0a0acd2c7d236deb8f219bf32a5cab11 818 Gene3D G3DSA:3.30.1360.40 247 344 5.1E-28 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain SMD11_RS08645 0a0acd2c7d236deb8f219bf32a5cab11 818 SMART SM00434 21 476 2.8E-257 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SMD11_RS23265 147f2b00e42c5a46123f7455556e7b2c 910 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 19 903 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMD11_RS23265 147f2b00e42c5a46123f7455556e7b2c 910 Gene3D G3DSA:3.40.50.920 725 897 3.6E-69 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS23265 147f2b00e42c5a46123f7455556e7b2c 910 SUPERFAMILY SSF52922 721 895 1.54E-52 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS23265 147f2b00e42c5a46123f7455556e7b2c 910 SUPERFAMILY SSF52518 488 717 1.77E-86 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS23265 147f2b00e42c5a46123f7455556e7b2c 910 PIRSF PIRSF000156 10 905 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMD11_RS23265 147f2b00e42c5a46123f7455556e7b2c 910 SUPERFAMILY SSF52518 70 482 1.85E-124 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS23265 147f2b00e42c5a46123f7455556e7b2c 910 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 150 307 1.5E-7 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS23265 147f2b00e42c5a46123f7455556e7b2c 910 Gene3D G3DSA:3.40.50.970 488 721 6.5E-110 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS23265 147f2b00e42c5a46123f7455556e7b2c 910 Gene3D G3DSA:3.40.50.970 70 483 1.4E-146 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS16570 a69007dd9f061c4a935fdaaa4ca8d5b0 365 SUPERFAMILY SSF53822 98 352 3.14E-35 T 06-07-2017 IPR028082 Periplasmic binding protein-like I SMD11_RS16570 a69007dd9f061c4a935fdaaa4ca8d5b0 365 Gene3D G3DSA:3.40.50.2300 187 349 3.4E-33 T 06-07-2017 SMD11_RS16570 a69007dd9f061c4a935fdaaa4ca8d5b0 365 Pfam PF00356 Bacterial regulatory proteins, lacI family 22 66 7.3E-14 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS16570 a69007dd9f061c4a935fdaaa4ca8d5b0 365 Pfam PF13377 Periplasmic binding protein-like domain 189 348 3.6E-29 T 06-07-2017 SMD11_RS16570 a69007dd9f061c4a935fdaaa4ca8d5b0 365 Gene3D G3DSA:1.10.260.40 21 75 1.7E-23 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS16570 a69007dd9f061c4a935fdaaa4ca8d5b0 365 ProSitePatterns PS00356 LacI-type HTH domain signature. 22 40 - T 06-07-2017 SMD11_RS16570 a69007dd9f061c4a935fdaaa4ca8d5b0 365 SMART SM00354 19 89 2.0E-20 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SMD11_RS16570 a69007dd9f061c4a935fdaaa4ca8d5b0 365 Gene3D G3DSA:3.40.50.2300 76 186 2.9E-9 T 06-07-2017 SMD11_RS16570 a69007dd9f061c4a935fdaaa4ca8d5b0 365 SUPERFAMILY SSF47413 19 77 2.57E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS17045 1512133e932781b16dabaf7f40b2c8a8 478 Pfam PF01098 Cell cycle protein 85 457 1.6E-70 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 SMD11_RS19315 cbdaa1259232ed40f05e2c002640160e 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 383 1.7E-23 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS19315 cbdaa1259232ed40f05e2c002640160e 389 Gene3D G3DSA:2.40.110.10 126 222 1.5E-34 T 06-07-2017 SMD11_RS19315 cbdaa1259232ed40f05e2c002640160e 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 123 2.2E-21 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS19315 cbdaa1259232ed40f05e2c002640160e 389 SUPERFAMILY SSF56645 2 244 1.7E-72 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS19315 cbdaa1259232ed40f05e2c002640160e 389 Gene3D G3DSA:1.20.140.10 223 387 3.0E-23 T 06-07-2017 SMD11_RS19315 cbdaa1259232ed40f05e2c002640160e 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 221 6.2E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS19315 cbdaa1259232ed40f05e2c002640160e 389 SUPERFAMILY SSF47203 233 385 9.33E-16 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS19315 cbdaa1259232ed40f05e2c002640160e 389 Gene3D G3DSA:1.10.540.10 1 125 2.4E-25 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS30740 9efea4048d743633df8d48fbb7f8a03f 228 Gene3D G3DSA:1.10.10.10 123 221 2.0E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30740 9efea4048d743633df8d48fbb7f8a03f 228 SUPERFAMILY SSF52172 1 130 7.97E-40 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS30740 9efea4048d743633df8d48fbb7f8a03f 228 SMART SM00448 1 112 8.4E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS30740 9efea4048d743633df8d48fbb7f8a03f 228 Gene3D G3DSA:3.40.50.2300 1 120 5.2E-40 T 06-07-2017 SMD11_RS30740 9efea4048d743633df8d48fbb7f8a03f 228 Pfam PF00072 Response regulator receiver domain 4 112 2.2E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS30740 9efea4048d743633df8d48fbb7f8a03f 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 2.3E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS30740 9efea4048d743633df8d48fbb7f8a03f 228 SUPERFAMILY SSF46894 118 221 4.82E-29 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS30740 9efea4048d743633df8d48fbb7f8a03f 228 SMART SM00862 145 220 2.1E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS30300 edccee33c42b908d2a3ae7c2482399ff 393 SUPERFAMILY SSF48264 8 391 8.77E-96 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30300 edccee33c42b908d2a3ae7c2482399ff 393 PRINTS PR00359 B-class P450 signature 131 147 5.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30300 edccee33c42b908d2a3ae7c2482399ff 393 PRINTS PR00359 B-class P450 signature 341 352 5.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30300 edccee33c42b908d2a3ae7c2482399ff 393 PRINTS PR00359 B-class P450 signature 283 310 5.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30300 edccee33c42b908d2a3ae7c2482399ff 393 PRINTS PR00359 B-class P450 signature 148 163 5.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30300 edccee33c42b908d2a3ae7c2482399ff 393 PRINTS PR00359 B-class P450 signature 184 206 5.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30300 edccee33c42b908d2a3ae7c2482399ff 393 PRINTS PR00359 B-class P450 signature 332 341 5.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30300 edccee33c42b908d2a3ae7c2482399ff 393 PRINTS PR00359 B-class P450 signature 265 276 5.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30300 edccee33c42b908d2a3ae7c2482399ff 393 PRINTS PR00359 B-class P450 signature 85 96 5.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30300 edccee33c42b908d2a3ae7c2482399ff 393 PRINTS PR00359 B-class P450 signature 311 326 5.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS30300 edccee33c42b908d2a3ae7c2482399ff 393 Gene3D G3DSA:1.10.630.10 5 390 9.3E-127 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30300 edccee33c42b908d2a3ae7c2482399ff 393 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 334 343 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS30300 edccee33c42b908d2a3ae7c2482399ff 393 Pfam PF00067 Cytochrome P450 173 254 5.0E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30300 edccee33c42b908d2a3ae7c2482399ff 393 Pfam PF00067 Cytochrome P450 266 362 2.5E-13 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS07625 eaa890e4d47843dbaa76f83ae3f64d42 422 Pfam PF00589 Phage integrase family 195 389 3.6E-17 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS07625 eaa890e4d47843dbaa76f83ae3f64d42 422 Gene3D G3DSA:1.10.150.130 83 181 2.8E-14 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal SMD11_RS07625 eaa890e4d47843dbaa76f83ae3f64d42 422 SUPERFAMILY SSF56349 83 397 2.21E-53 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD11_RS07625 eaa890e4d47843dbaa76f83ae3f64d42 422 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 84 133 6.8E-6 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SMD11_RS07625 eaa890e4d47843dbaa76f83ae3f64d42 422 Gene3D G3DSA:1.10.443.10 188 397 1.6E-34 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS17825 29c70730efcabc916f7e8a1945baae61 419 SUPERFAMILY SSF52440 2 101 6.19E-30 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS17825 29c70730efcabc916f7e8a1945baae61 419 Gene3D G3DSA:3.30.1490.20 122 178 1.3E-16 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS17825 29c70730efcabc916f7e8a1945baae61 419 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 319 411 2.3E-27 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD11_RS17825 29c70730efcabc916f7e8a1945baae61 419 SMART SM01210 318 413 2.5E-43 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD11_RS17825 29c70730efcabc916f7e8a1945baae61 419 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 277 284 - T 06-07-2017 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD11_RS17825 29c70730efcabc916f7e8a1945baae61 419 SUPERFAMILY SSF56059 102 307 9.9E-54 T 06-07-2017 SMD11_RS17825 29c70730efcabc916f7e8a1945baae61 419 Gene3D G3DSA:3.90.600.10 318 412 5.5E-33 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD11_RS17825 29c70730efcabc916f7e8a1945baae61 419 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 283 2.2E-64 T 06-07-2017 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD11_RS17825 29c70730efcabc916f7e8a1945baae61 419 Gene3D G3DSA:3.40.50.20 2 93 9.2E-33 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS17825 29c70730efcabc916f7e8a1945baae61 419 SMART SM01209 101 283 4.1E-113 T 06-07-2017 SMD11_RS17825 29c70730efcabc916f7e8a1945baae61 419 Gene3D G3DSA:3.30.470.20 179 316 7.4E-56 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS17825 29c70730efcabc916f7e8a1945baae61 419 SUPERFAMILY SSF51246 316 412 4.34E-26 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS17825 29c70730efcabc916f7e8a1945baae61 419 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 413 5.2E-142 T 06-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD11_RS17825 29c70730efcabc916f7e8a1945baae61 419 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 413 40.652 T 06-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD11_RS17825 29c70730efcabc916f7e8a1945baae61 419 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 6.7E-30 T 06-07-2017 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD11_RS21850 ece7660988b6923acea0b905d76eca7a 631 Gene3D G3DSA:3.40.50.1220 218 369 8.4E-40 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS21850 ece7660988b6923acea0b905d76eca7a 631 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 424 582 2.1E-39 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMD11_RS21850 ece7660988b6923acea0b905d76eca7a 631 SUPERFAMILY SSF52518 402 619 3.13E-48 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS21850 ece7660988b6923acea0b905d76eca7a 631 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 12 628 3.3E-270 T 06-07-2017 IPR030817 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 SMD11_RS21850 ece7660988b6923acea0b905d76eca7a 631 SUPERFAMILY SSF52518 10 217 1.08E-29 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS21850 ece7660988b6923acea0b905d76eca7a 631 Gene3D G3DSA:3.40.50.970 397 622 5.0E-56 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS21850 ece7660988b6923acea0b905d76eca7a 631 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 227 360 2.0E-31 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMD11_RS21850 ece7660988b6923acea0b905d76eca7a 631 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 14 206 3.1E-33 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMD11_RS21850 ece7660988b6923acea0b905d76eca7a 631 SUPERFAMILY SSF52467 193 374 3.44E-41 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS21850 ece7660988b6923acea0b905d76eca7a 631 Gene3D G3DSA:3.40.50.970 9 217 9.0E-61 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS19820 51eb4df6520a4140aeb1ff6ca1e971ca 296 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 22 291 40.834 T 06-07-2017 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 SMD11_RS19820 51eb4df6520a4140aeb1ff6ca1e971ca 296 SUPERFAMILY SSF53167 22 285 2.23E-80 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD11_RS19820 51eb4df6520a4140aeb1ff6ca1e971ca 296 Gene3D G3DSA:3.40.50.1580 21 285 1.5E-83 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD11_RS19820 51eb4df6520a4140aeb1ff6ca1e971ca 296 Pfam PF01048 Phosphorylase superfamily 23 268 9.6E-42 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD11_RS19820 51eb4df6520a4140aeb1ff6ca1e971ca 296 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 24 270 6.1E-87 T 06-07-2017 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 SMD11_RS02365 95a41410199465bd403409c361f40c60 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 1.1E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS02365 95a41410199465bd403409c361f40c60 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 1.1E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS02365 95a41410199465bd403409c361f40c60 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 1.1E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS02365 95a41410199465bd403409c361f40c60 152 Gene3D G3DSA:3.30.70.920 59 150 2.4E-21 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS02365 95a41410199465bd403409c361f40c60 152 Gene3D G3DSA:1.10.10.10 5 58 2.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02365 95a41410199465bd403409c361f40c60 152 Pfam PF01037 Lrp/AsnC ligand binding domain 75 147 6.9E-16 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS02365 95a41410199465bd403409c361f40c60 152 SUPERFAMILY SSF54909 73 151 7.91E-15 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS02365 95a41410199465bd403409c361f40c60 152 SMART SM00344 7 116 1.3E-36 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD11_RS02365 95a41410199465bd403409c361f40c60 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 53 1.2E-19 T 06-07-2017 SMD11_RS02365 95a41410199465bd403409c361f40c60 152 SUPERFAMILY SSF46785 6 66 1.21E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02365 95a41410199465bd403409c361f40c60 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 25 51 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMD11_RS32150 92c9230518224630e89c2b35ff20a499 541 Gene3D G3DSA:3.40.50.1820 228 331 1.3E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32150 92c9230518224630e89c2b35ff20a499 541 Gene3D G3DSA:3.40.50.1820 8 156 1.3E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32150 92c9230518224630e89c2b35ff20a499 541 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 318 509 6.4E-29 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMD11_RS32150 92c9230518224630e89c2b35ff20a499 541 SMART SM00939 301 527 2.4E-54 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMD11_RS32150 92c9230518224630e89c2b35ff20a499 541 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 27 286 1.1E-48 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SMD11_RS32150 92c9230518224630e89c2b35ff20a499 541 Gene3D G3DSA:2.60.120.260 332 529 1.3E-61 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS32150 92c9230518224630e89c2b35ff20a499 541 SUPERFAMILY SSF49785 331 529 9.57E-46 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS32150 92c9230518224630e89c2b35ff20a499 541 SUPERFAMILY SSF53474 9 337 7.36E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32150 92c9230518224630e89c2b35ff20a499 541 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 24 523 4.2E-87 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 SUPERFAMILY SSF49303 231 344 2.1E-23 T 06-07-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 Gene3D G3DSA:3.20.20.80 351 622 5.3E-101 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 Gene3D G3DSA:2.60.40.320 623 731 1.8E-34 T 06-07-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 54 229 3.8E-37 T 06-07-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 351 626 1.5E-99 T 06-07-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 SMART SM01038 755 1032 2.2E-88 T 06-07-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 SUPERFAMILY SSF74650 744 1033 2.04E-74 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 Gene3D G3DSA:2.60.120.260 17 219 4.1E-74 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 SUPERFAMILY SSF51445 351 623 4.27E-88 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 Pfam PF00703 Glycosyl hydrolases family 2 231 344 1.4E-16 T 06-07-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 396 421 - T 06-07-2017 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 Gene3D G3DSA:2.60.40.320 220 344 6.0E-31 T 06-07-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 Pfam PF02929 Beta galactosidase small chain 763 1031 5.0E-59 T 06-07-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 Pfam PF16353 Domain of unknown function(DUF4981) 637 727 1.5E-28 T 06-07-2017 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 SUPERFAMILY SSF49303 619 730 8.63E-34 T 06-07-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 SUPERFAMILY SSF49785 18 229 5.1E-59 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 Gene3D G3DSA:2.70.98.10 743 1033 8.9E-76 T 06-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 457 471 - T 06-07-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 PRINTS PR00132 Glycosyl hydrolase family 2 signature 526 541 2.8E-37 T 06-07-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 PRINTS PR00132 Glycosyl hydrolase family 2 signature 153 168 2.8E-37 T 06-07-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 PRINTS PR00132 Glycosyl hydrolase family 2 signature 355 369 2.8E-37 T 06-07-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 PRINTS PR00132 Glycosyl hydrolase family 2 signature 386 404 2.8E-37 T 06-07-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 SMD11_RS03545 162760ed0e5a6bb330600bf8eab8372f 1035 PRINTS PR00132 Glycosyl hydrolase family 2 signature 457 472 2.8E-37 T 06-07-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 SMD11_RS31580 c459af44d67e8b7a87ab7165eef7cdc1 842 SUPERFAMILY SSF56801 417 741 1.01E-26 T 06-07-2017 SMD11_RS31580 c459af44d67e8b7a87ab7165eef7cdc1 842 SUPERFAMILY SSF53720 16 338 1.31E-15 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS31580 c459af44d67e8b7a87ab7165eef7cdc1 842 Gene3D G3DSA:3.40.50.980 539 655 4.1E-11 T 06-07-2017 SMD11_RS31580 c459af44d67e8b7a87ab7165eef7cdc1 842 Pfam PF00501 AMP-binding enzyme 497 695 2.8E-8 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS31580 c459af44d67e8b7a87ab7165eef7cdc1 842 Pfam PF05893 Acyl-CoA reductase (LuxC) 47 441 1.7E-87 T 06-07-2017 IPR008670 Acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 SMD11_RS31580 c459af44d67e8b7a87ab7165eef7cdc1 842 Gene3D G3DSA:3.40.605.10 103 286 3.6E-8 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 Pfam PF00698 Acyl transferase domain 549 857 5.3E-49 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 396 501 9.2E-14 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 SMART SM00823 Phosphopantetheine attachment site 921 993 6.0E-5 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 Pfam PF00550 Phosphopantetheine attachment site 924 989 7.3E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 Gene3D G3DSA:1.10.1200.10 918 992 2.8E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 275 393 3.2E-36 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 SUPERFAMILY SSF53901 421 442 5.87E-80 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 SUPERFAMILY SSF53901 9 128 5.87E-80 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 SUPERFAMILY SSF53901 163 389 5.87E-80 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 SUPERFAMILY SSF55048 675 738 1.18E-8 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 Gene3D G3DSA:3.30.70.250 674 737 2.0E-4 T 06-07-2017 SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 14 267 1.8E-60 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 SMART SM00825 Beta-ketoacyl synthase 13 446 1.2E-154 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 Gene3D G3DSA:3.40.47.10 280 447 9.8E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 Gene3D G3DSA:3.40.366.10 543 670 4.2E-63 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 Gene3D G3DSA:3.40.366.10 738 845 4.2E-63 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 Gene3D G3DSA:3.40.47.10 14 279 2.6E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 549 844 3.5E-72 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 SUPERFAMILY SSF47336 917 1009 9.55E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 SUPERFAMILY SSF52151 739 836 3.14E-61 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS28520 2a30aad2d74effc83de635db44576cef 1121 SUPERFAMILY SSF52151 545 676 3.14E-61 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS07985 d1d491a0ccb0e355560eac24aa76634c 134 Hamap MF_01197 Cell division protein SepF [sepF]. 11 125 14.418 T 06-07-2017 IPR023052 Cell division protein SepF GO:0090529 SMD11_RS07985 d1d491a0ccb0e355560eac24aa76634c 134 Pfam PF04472 Protein of unknown function (DUF552) 47 117 1.9E-20 T 06-07-2017 IPR007561 Cell division protein SepF/SepF-related GO:0090529 SMD11_RS15400 8c3c0a8cfdb926b9914a6021df313805 227 Pfam PF00293 NUDIX domain 47 167 1.6E-10 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS15400 8c3c0a8cfdb926b9914a6021df313805 227 SUPERFAMILY SSF55811 44 205 7.47E-26 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS15400 8c3c0a8cfdb926b9914a6021df313805 227 Gene3D G3DSA:3.90.79.10 43 209 6.2E-36 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS17580 a557170c525ac3115a143ec259137770 339 Pfam PF04893 Yip1 domain 173 330 5.7E-11 T 06-07-2017 IPR006977 Yip1 domain GO:0016020 SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 SUPERFAMILY SSF52540 485 786 1.2E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 ProSitePatterns PS00211 ABC transporters family signature. 703 717 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 SMART SM00382 37 427 16.0 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 SMART SM00382 502 781 0.026 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 SUPERFAMILY SSF52540 294 441 7.26E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 SUPERFAMILY SSF52540 19 66 7.26E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 Gene3D G3DSA:1.10.8.280 168 279 7.2E-23 T 06-07-2017 SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 Gene3D G3DSA:3.40.50.300 472 542 2.0E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 Gene3D G3DSA:3.40.50.300 9 65 5.5E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 Gene3D G3DSA:3.40.50.300 694 802 2.0E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 Gene3D G3DSA:3.40.50.300 350 463 5.5E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 Pfam PF00005 ABC transporter 494 733 8.0E-7 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 Gene3D G3DSA:1.20.1580.10 280 349 7.1E-30 T 06-07-2017 SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 Gene3D G3DSA:1.20.1580.10 567 693 1.5E-44 T 06-07-2017 SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 Gene3D G3DSA:1.20.1580.10 107 167 7.1E-30 T 06-07-2017 SMD11_RS03975 c5dd05834fa6783b21be96925fcaaa9d 817 ProSitePatterns PS00211 ABC transporters family signature. 359 373 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS25455 78f15e33cfbabff6a2861e4ebde26f31 140 Pfam PF03780 Asp23 family, cell envelope-related function 16 126 5.4E-30 T 06-07-2017 IPR005531 Alkaline shock protein Asp23 SMD11_RS00165 ebb3741edc899e9a853395b77e2fb490 105 Pfam PF13586 Transposase DDE domain 9 104 2.2E-17 T 06-07-2017 IPR025668 Transposase DDE domain SMD11_RS05855 5b053cfd355cbeeb503a4980a61517ec 589 SMART SM00857 15 164 1.5E-21 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD11_RS05855 5b053cfd355cbeeb503a4980a61517ec 589 Gene3D G3DSA:3.40.50.1390 14 147 1.2E-15 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD11_RS05855 5b053cfd355cbeeb503a4980a61517ec 589 Pfam PF00239 Resolvase, N terminal domain 16 162 4.2E-19 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD11_RS05855 5b053cfd355cbeeb503a4980a61517ec 589 SUPERFAMILY SSF53041 14 164 1.05E-20 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SMD11_RS10855 d4d17ddc16dfd25c86db49df3270a4e9 73 SUPERFAMILY SSF143800 1 67 3.1E-24 T 06-07-2017 SMD11_RS10855 d4d17ddc16dfd25c86db49df3270a4e9 73 Pfam PF01197 Ribosomal protein L31 2 66 9.9E-30 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS10855 d4d17ddc16dfd25c86db49df3270a4e9 73 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS10855 d4d17ddc16dfd25c86db49df3270a4e9 73 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 28.404 T 06-07-2017 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS10855 d4d17ddc16dfd25c86db49df3270a4e9 73 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 67 3.2E-33 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS10855 d4d17ddc16dfd25c86db49df3270a4e9 73 PRINTS PR01249 Ribosomal protein L31 signature 47 65 2.8E-20 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS10855 d4d17ddc16dfd25c86db49df3270a4e9 73 PRINTS PR01249 Ribosomal protein L31 signature 32 47 2.8E-20 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS10855 d4d17ddc16dfd25c86db49df3270a4e9 73 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.8E-20 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS03370 71ac33d9fbb44fbb762195768b206460 202 SUPERFAMILY SSF52218 4 196 1.23E-51 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS03370 71ac33d9fbb44fbb762195768b206460 202 Pfam PF03358 NADPH-dependent FMN reductase 5 149 3.6E-13 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMD11_RS03370 71ac33d9fbb44fbb762195768b206460 202 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 5 196 1.2E-49 T 06-07-2017 IPR010089 Flavoprotein WrbA GO:0010181|GO:0045892 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 SMD11_RS03370 71ac33d9fbb44fbb762195768b206460 202 Gene3D G3DSA:3.40.50.360 2 197 6.9E-66 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS03165 0db7605acb368dffe59981276e876918 407 Pfam PF07690 Major Facilitator Superfamily 38 216 4.1E-13 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS03165 0db7605acb368dffe59981276e876918 407 Pfam PF07690 Major Facilitator Superfamily 243 396 1.1E-10 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS03165 0db7605acb368dffe59981276e876918 407 Gene3D G3DSA:1.20.1250.20 30 198 1.4E-14 T 06-07-2017 SMD11_RS03165 0db7605acb368dffe59981276e876918 407 Gene3D G3DSA:1.20.1250.20 234 395 2.3E-17 T 06-07-2017 SMD11_RS03165 0db7605acb368dffe59981276e876918 407 SUPERFAMILY SSF103473 23 400 3.14E-42 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS06530 e35619c8591e16fa484210794386d3f0 565 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 66 513 1.0E-160 T 06-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 SMD11_RS06530 e35619c8591e16fa484210794386d3f0 565 ProSitePatterns PS01303 BCCT family of transporters signature. 331 340 - T 06-07-2017 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 SMD11_RS06530 e35619c8591e16fa484210794386d3f0 565 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 29 513 1.0E-186 T 06-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 SMD11_RS21970 e6d244798a2023d8ca30ead8e89af930 863 Pfam PF13424 Tetratricopeptide repeat 731 804 6.3E-9 T 06-07-2017 SMD11_RS21970 e6d244798a2023d8ca30ead8e89af930 863 Gene3D G3DSA:3.40.50.300 204 330 3.3E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21970 e6d244798a2023d8ca30ead8e89af930 863 SMART SM00382 205 343 2.2E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS21970 e6d244798a2023d8ca30ead8e89af930 863 SUPERFAMILY SSF52540 202 449 2.8E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21970 e6d244798a2023d8ca30ead8e89af930 863 SUPERFAMILY SSF48452 646 801 1.86E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS21970 e6d244798a2023d8ca30ead8e89af930 863 PRINTS PR00364 Disease resistance protein signature 208 223 5.3E-7 T 06-07-2017 SMD11_RS21970 e6d244798a2023d8ca30ead8e89af930 863 PRINTS PR00364 Disease resistance protein signature 286 300 5.3E-7 T 06-07-2017 SMD11_RS21970 e6d244798a2023d8ca30ead8e89af930 863 PRINTS PR00364 Disease resistance protein signature 374 388 5.3E-7 T 06-07-2017 SMD11_RS21970 e6d244798a2023d8ca30ead8e89af930 863 Gene3D G3DSA:1.25.40.10 567 590 1.4E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS21970 e6d244798a2023d8ca30ead8e89af930 863 Gene3D G3DSA:1.25.40.10 628 811 1.4E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS03565 0473edb9a9d70fea284365b20471087b 605 SMART SM00382 388 574 1.3E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS03565 0473edb9a9d70fea284365b20471087b 605 ProSitePatterns PS00211 ABC transporters family signature. 500 514 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS03565 0473edb9a9d70fea284365b20471087b 605 Pfam PF00664 ABC transporter transmembrane region 36 309 4.1E-38 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS03565 0473edb9a9d70fea284365b20471087b 605 Gene3D G3DSA:3.40.50.300 356 593 4.9E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03565 0473edb9a9d70fea284365b20471087b 605 Gene3D G3DSA:1.20.1560.10 22 343 6.9E-68 T 06-07-2017 SMD11_RS03565 0473edb9a9d70fea284365b20471087b 605 SUPERFAMILY SSF52540 345 596 4.91E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03565 0473edb9a9d70fea284365b20471087b 605 SUPERFAMILY SSF90123 16 343 2.49E-68 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS03565 0473edb9a9d70fea284365b20471087b 605 Pfam PF00005 ABC transporter 379 528 3.1E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS08585 ee164c9c12c7ab7adb9e84f2bb8cec85 359 Pfam PF11268 Protein of unknown function (DUF3071) 12 179 2.8E-55 T 06-07-2017 IPR021421 Protein of unknown function DUF3071 SMD11_RS00535 b6b86560dc131239ba4090da735be0cf 65 SUPERFAMILY SSF47413 4 59 1.01E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS00535 b6b86560dc131239ba4090da735be0cf 65 Pfam PF01381 Helix-turn-helix 6 57 5.3E-16 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS00535 b6b86560dc131239ba4090da735be0cf 65 SMART SM00530 5 60 7.1E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS00535 b6b86560dc131239ba4090da735be0cf 65 Gene3D G3DSA:1.10.260.40 4 57 3.9E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS05650 75ecdf8e0349b736167dd895f7b2670f 211 SMART SM00448 2 115 1.5E-18 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS05650 75ecdf8e0349b736167dd895f7b2670f 211 SMART SM00421 147 204 1.0E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS05650 75ecdf8e0349b736167dd895f7b2670f 211 SUPERFAMILY SSF52172 2 130 5.98E-28 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS05650 75ecdf8e0349b736167dd895f7b2670f 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 2.0E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS05650 75ecdf8e0349b736167dd895f7b2670f 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 2.0E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS05650 75ecdf8e0349b736167dd895f7b2670f 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 2.0E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS05650 75ecdf8e0349b736167dd895f7b2670f 211 Gene3D G3DSA:3.40.50.2300 2 153 2.3E-30 T 06-07-2017 SMD11_RS05650 75ecdf8e0349b736167dd895f7b2670f 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 3.4E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS05650 75ecdf8e0349b736167dd895f7b2670f 211 Pfam PF00072 Response regulator receiver domain 4 116 3.0E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS05650 75ecdf8e0349b736167dd895f7b2670f 211 Gene3D G3DSA:1.10.10.10 154 210 1.8E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05650 75ecdf8e0349b736167dd895f7b2670f 211 SUPERFAMILY SSF46894 140 210 1.73E-16 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS19845 25376d3564b80f13f8ad72dea26b9132 212 Gene3D G3DSA:3.40.50.10420 18 205 1.7E-48 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain SMD11_RS19845 25376d3564b80f13f8ad72dea26b9132 212 PIRSF PIRSF006806 15 202 3.9E-32 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase SMD11_RS19845 25376d3564b80f13f8ad72dea26b9132 212 SUPERFAMILY SSF100950 17 209 2.51E-43 T 06-07-2017 SMD11_RS19845 25376d3564b80f13f8ad72dea26b9132 212 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 18 199 5.9E-42 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase SMD11_RS19845 25376d3564b80f13f8ad72dea26b9132 212 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 18 199 1.2E-38 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase SMD11_RS28640 ff10564fa35e56c22290f061f4616b11 363 Pfam PF01112 Asparaginase 47 348 1.2E-100 T 06-07-2017 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 SMD11_RS28640 ff10564fa35e56c22290f061f4616b11 363 SUPERFAMILY SSF56235 46 354 9.0E-82 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS04555 669930d943315a9bdc86d34960f73eb4 188 Pfam PF13977 Bacterial transcriptional repressor 105 169 2.2E-6 T 06-07-2017 SMD11_RS04555 669930d943315a9bdc86d34960f73eb4 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 5.9E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS04555 669930d943315a9bdc86d34960f73eb4 188 Gene3D G3DSA:1.10.357.10 3 182 2.4E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS04555 669930d943315a9bdc86d34960f73eb4 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 3.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS04555 669930d943315a9bdc86d34960f73eb4 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 3.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS04555 669930d943315a9bdc86d34960f73eb4 188 SUPERFAMILY SSF48498 74 182 4.45E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS04555 669930d943315a9bdc86d34960f73eb4 188 SUPERFAMILY SSF46689 3 78 2.62E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS34095 8026dbf85b76d08ef2370cf538f859d3 354 Gene3D G3DSA:1.10.600.10 13 324 3.3E-53 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS34095 8026dbf85b76d08ef2370cf538f859d3 354 SUPERFAMILY SSF48576 28 327 2.39E-37 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS34095 8026dbf85b76d08ef2370cf538f859d3 354 Pfam PF03936 Terpene synthase family, metal binding domain 76 278 2.8E-7 T 06-07-2017 IPR005630 Terpene synthase, metal-binding domain GO:0000287|GO:0010333|GO:0016829 SMD11_RS33090 76dae40a517280da18c3dca806a85840 252 SUPERFAMILY SSF46894 178 252 2.55E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS33090 76dae40a517280da18c3dca806a85840 252 Pfam PF00196 Bacterial regulatory proteins, luxR family 191 246 6.0E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS33090 76dae40a517280da18c3dca806a85840 252 Gene3D G3DSA:1.10.10.10 192 252 6.3E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33090 76dae40a517280da18c3dca806a85840 252 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 222 234 5.9E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS33090 76dae40a517280da18c3dca806a85840 252 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 206 5.9E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS33090 76dae40a517280da18c3dca806a85840 252 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 206 222 5.9E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS33090 76dae40a517280da18c3dca806a85840 252 SMART SM00421 189 246 6.3E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS12155 2e819bbc3b51245447e236ffadc8cc7a 343 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 19 326 4.2E-141 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 SMD11_RS12155 2e819bbc3b51245447e236ffadc8cc7a 343 PIRSF PIRSF004532 17 337 9.4E-145 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 SMD11_RS12155 2e819bbc3b51245447e236ffadc8cc7a 343 Gene3D G3DSA:3.30.540.10 17 189 1.2E-62 T 06-07-2017 SMD11_RS12155 2e819bbc3b51245447e236ffadc8cc7a 343 Gene3D G3DSA:3.30.540.10 190 335 1.7E-45 T 06-07-2017 SMD11_RS12155 2e819bbc3b51245447e236ffadc8cc7a 343 SUPERFAMILY SSF56655 17 329 6.41E-110 T 06-07-2017 SMD11_RS12155 2e819bbc3b51245447e236ffadc8cc7a 343 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 19 330 3.7E-117 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 SMD11_RS16270 f42274b37a401f1ce4a0c75653fed81f 587 PRINTS PR00834 HtrA/DegQ protease family signature 299 311 4.3E-45 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS16270 f42274b37a401f1ce4a0c75653fed81f 587 PRINTS PR00834 HtrA/DegQ protease family signature 432 449 4.3E-45 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS16270 f42274b37a401f1ce4a0c75653fed81f 587 PRINTS PR00834 HtrA/DegQ protease family signature 527 539 4.3E-45 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS16270 f42274b37a401f1ce4a0c75653fed81f 587 PRINTS PR00834 HtrA/DegQ protease family signature 324 344 4.3E-45 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS16270 f42274b37a401f1ce4a0c75653fed81f 587 PRINTS PR00834 HtrA/DegQ protease family signature 367 391 4.3E-45 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS16270 f42274b37a401f1ce4a0c75653fed81f 587 PRINTS PR00834 HtrA/DegQ protease family signature 410 427 4.3E-45 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS16270 f42274b37a401f1ce4a0c75653fed81f 587 Pfam PF13180 PDZ domain 491 578 2.0E-23 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS16270 f42274b37a401f1ce4a0c75653fed81f 587 Pfam PF13365 Trypsin-like peptidase domain 290 439 9.2E-33 T 06-07-2017 SMD11_RS16270 f42274b37a401f1ce4a0c75653fed81f 587 Gene3D G3DSA:2.30.42.10 515 585 4.0E-19 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS16270 f42274b37a401f1ce4a0c75653fed81f 587 Gene3D G3DSA:2.40.10.10 362 491 1.3E-39 T 06-07-2017 SMD11_RS16270 f42274b37a401f1ce4a0c75653fed81f 587 SMART SM00228 500 569 2.8E-6 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS16270 f42274b37a401f1ce4a0c75653fed81f 587 SUPERFAMILY SSF50156 515 582 4.07E-18 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS16270 f42274b37a401f1ce4a0c75653fed81f 587 SUPERFAMILY SSF50494 262 482 6.27E-55 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS16270 f42274b37a401f1ce4a0c75653fed81f 587 Gene3D G3DSA:2.40.10.10 256 361 4.9E-26 T 06-07-2017 SMD11_RS14430 6a8b192584373206aa1773c8651d9abc 363 Gene3D G3DSA:1.10.3470.10 27 357 5.2E-99 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS14430 6a8b192584373206aa1773c8651d9abc 363 Pfam PF01032 FecCD transport family 35 355 2.3E-88 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD11_RS14430 6a8b192584373206aa1773c8651d9abc 363 SUPERFAMILY SSF81345 24 356 6.67E-77 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 SUPERFAMILY SSF81442 20 531 3.4E-175 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 297 312 3.4E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 121 3.4E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 382 401 3.4E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 230 251 3.4E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 319 340 3.4E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 432 453 3.4E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 172 190 3.4E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 201 220 3.4E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 140 152 3.4E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 251 272 3.4E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 354 372 3.4E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 70 93 3.4E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 23 48 3.4E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 32 476 1.2E-145 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 Gene3D G3DSA:1.20.210.10 16 545 7.1E-194 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 24 528 3.4E-211 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 SMD11_RS25895 c4cc8bbd3eaa4af1b4ebf113c9ba0ee5 560 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 253 307 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS03450 996385ec8a3c94668a76a7772011d3cc 321 Pfam PF02678 Pirin 41 141 1.1E-22 T 06-07-2017 IPR003829 Pirin, N-terminal domain SMD11_RS03450 996385ec8a3c94668a76a7772011d3cc 321 PIRSF PIRSF006232 21 301 5.9E-79 T 06-07-2017 IPR012093 Pirin SMD11_RS03450 996385ec8a3c94668a76a7772011d3cc 321 Pfam PF05726 Pirin C-terminal cupin domain 193 291 4.0E-21 T 06-07-2017 IPR008778 Pirin, C-terminal domain SMD11_RS03450 996385ec8a3c94668a76a7772011d3cc 321 SUPERFAMILY SSF51182 36 303 5.34E-67 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS03450 996385ec8a3c94668a76a7772011d3cc 321 Gene3D G3DSA:2.60.120.10 29 265 5.2E-59 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS33865 2b3958d98e8ada3dbe09ab142a7082b8 424 Gene3D G3DSA:1.20.1250.20 232 415 4.6E-21 T 06-07-2017 SMD11_RS33865 2b3958d98e8ada3dbe09ab142a7082b8 424 Gene3D G3DSA:1.20.1250.20 23 211 2.6E-25 T 06-07-2017 SMD11_RS33865 2b3958d98e8ada3dbe09ab142a7082b8 424 Pfam PF07690 Major Facilitator Superfamily 275 416 1.3E-13 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS33865 2b3958d98e8ada3dbe09ab142a7082b8 424 Pfam PF07690 Major Facilitator Superfamily 36 271 8.9E-21 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS33865 2b3958d98e8ada3dbe09ab142a7082b8 424 SUPERFAMILY SSF103473 10 416 1.57E-54 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS07260 4bbd43b895efd45aaf2e4c7dfa74faed 155 SUPERFAMILY SSF51110 51 153 1.8E-24 T 06-07-2017 IPR001480 Bulb-type lectin domain SMD11_RS07260 4bbd43b895efd45aaf2e4c7dfa74faed 155 Gene3D G3DSA:2.90.10.10 47 153 4.0E-30 T 06-07-2017 IPR001480 Bulb-type lectin domain SMD11_RS07260 4bbd43b895efd45aaf2e4c7dfa74faed 155 SMART SM00108 48 155 1.2E-13 T 06-07-2017 IPR001480 Bulb-type lectin domain SMD11_RS07260 4bbd43b895efd45aaf2e4c7dfa74faed 155 Pfam PF01453 D-mannose binding lectin 57 125 2.6E-15 T 06-07-2017 IPR001480 Bulb-type lectin domain SMD11_RS15410 c06f23474301de5f4c22f4bdbeb2c3c4 224 SMART SM00100 10 128 2.9E-26 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain SMD11_RS15410 c06f23474301de5f4c22f4bdbeb2c3c4 224 Pfam PF00027 Cyclic nucleotide-binding domain 30 110 9.5E-26 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain SMD11_RS15410 c06f23474301de5f4c22f4bdbeb2c3c4 224 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 78 95 - T 06-07-2017 IPR018488 Cyclic nucleotide-binding, conserved site SMD11_RS15410 c06f23474301de5f4c22f4bdbeb2c3c4 224 Gene3D G3DSA:2.60.120.10 2 142 4.3E-40 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS15410 c06f23474301de5f4c22f4bdbeb2c3c4 224 Gene3D G3DSA:1.10.10.10 145 222 6.5E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15410 c06f23474301de5f4c22f4bdbeb2c3c4 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 7.8E-17 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMD11_RS15410 c06f23474301de5f4c22f4bdbeb2c3c4 224 SMART SM00419 167 215 2.1E-13 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMD11_RS15410 c06f23474301de5f4c22f4bdbeb2c3c4 224 PRINTS PR00103 cAMP-dependent protein kinase signature 31 45 2.4E-6 T 06-07-2017 SMD11_RS15410 c06f23474301de5f4c22f4bdbeb2c3c4 224 PRINTS PR00103 cAMP-dependent protein kinase signature 46 60 2.4E-6 T 06-07-2017 SMD11_RS15410 c06f23474301de5f4c22f4bdbeb2c3c4 224 PRINTS PR00103 cAMP-dependent protein kinase signature 76 85 2.4E-6 T 06-07-2017 SMD11_RS15410 c06f23474301de5f4c22f4bdbeb2c3c4 224 PRINTS PR00103 cAMP-dependent protein kinase signature 88 99 2.4E-6 T 06-07-2017 SMD11_RS15410 c06f23474301de5f4c22f4bdbeb2c3c4 224 SUPERFAMILY SSF51206 3 142 7.99E-39 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like SMD11_RS15410 c06f23474301de5f4c22f4bdbeb2c3c4 224 SUPERFAMILY SSF46785 145 222 3.56E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS25860 0cfeb7067c98db2a3bff684596eafe5b 242 Gene3D G3DSA:3.40.50.300 21 237 3.8E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25860 0cfeb7067c98db2a3bff684596eafe5b 242 TIGRFAM TIGR00017 cmk: cytidylate kinase 21 234 2.4E-64 T 06-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 SMD11_RS25860 0cfeb7067c98db2a3bff684596eafe5b 242 Pfam PF02224 Cytidylate kinase 23 237 1.3E-66 T 06-07-2017 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 SMD11_RS25860 0cfeb7067c98db2a3bff684596eafe5b 242 Hamap MF_00238 Cytidylate kinase [cmk]. 21 240 30.923 T 06-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 SMD11_RS25860 0cfeb7067c98db2a3bff684596eafe5b 242 SUPERFAMILY SSF52540 21 239 3.14E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14000 07507d4e927d265c84b4a56abc27e66d 191 Gene3D G3DSA:2.60.60.30 18 185 1.7E-71 T 06-07-2017 SMD11_RS14000 07507d4e927d265c84b4a56abc27e66d 191 Pfam PF02342 TerD domain 1 187 2.0E-83 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS14545 709e5cae06a5e024142fe3ab14e7b1a6 371 Gene3D G3DSA:3.90.1720.10 254 358 5.0E-36 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS14545 709e5cae06a5e024142fe3ab14e7b1a6 371 Pfam PF00877 NlpC/P60 family 271 354 1.5E-19 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS14545 709e5cae06a5e024142fe3ab14e7b1a6 371 SUPERFAMILY SSF54001 257 360 7.85E-33 T 06-07-2017 SMD11_RS01695 97c2cf57678b84b2fcb857d7cf2aefa0 273 SMART SM00871 119 271 1.9E-12 T 06-07-2017 IPR010499 Bacterial transcription activator, effector binding SMD11_RS01695 97c2cf57678b84b2fcb857d7cf2aefa0 273 Gene3D G3DSA:3.20.80.10 120 271 2.2E-5 T 06-07-2017 IPR011256 Regulatory factor, effector binding domain SMD11_RS01695 97c2cf57678b84b2fcb857d7cf2aefa0 273 SUPERFAMILY SSF55136 120 272 1.45E-20 T 06-07-2017 IPR011256 Regulatory factor, effector binding domain SMD11_RS01695 97c2cf57678b84b2fcb857d7cf2aefa0 273 Pfam PF13411 MerR HTH family regulatory protein 2 71 7.7E-16 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS01695 97c2cf57678b84b2fcb857d7cf2aefa0 273 Gene3D G3DSA:1.10.1660.10 1 57 3.1E-22 T 06-07-2017 SMD11_RS01695 97c2cf57678b84b2fcb857d7cf2aefa0 273 SUPERFAMILY SSF46955 2 114 1.1E-23 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS01695 97c2cf57678b84b2fcb857d7cf2aefa0 273 Gene3D G3DSA:1.10.1660.10 58 115 1.6E-5 T 06-07-2017 SMD11_RS01695 97c2cf57678b84b2fcb857d7cf2aefa0 273 Pfam PF06445 GyrI-like small molecule binding domain 121 270 6.2E-10 T 06-07-2017 IPR029442 GyrI-like small molecule binding domain SMD11_RS01695 97c2cf57678b84b2fcb857d7cf2aefa0 273 SMART SM00422 2 72 6.1E-17 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS00455 8c3a29e718c856c2d80215baae1002f5 204 Pfam PF00484 Carbonic anhydrase 34 189 7.0E-50 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS00455 8c3a29e718c856c2d80215baae1002f5 204 SMART SM00947 27 193 4.3E-61 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS00455 8c3a29e718c856c2d80215baae1002f5 204 Gene3D G3DSA:3.40.1050.10 1 202 2.9E-71 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS00455 8c3a29e718c856c2d80215baae1002f5 204 SUPERFAMILY SSF53056 2 201 1.44E-60 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS00455 8c3a29e718c856c2d80215baae1002f5 204 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 06-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS15700 d764f421c589e9ceca421d5b2d25e622 292 SUPERFAMILY SSF88946 7 89 1.41E-15 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS15700 d764f421c589e9ceca421d5b2d25e622 292 Gene3D G3DSA:1.10.1740.10 7 99 2.3E-17 T 06-07-2017 SMD11_RS15700 d764f421c589e9ceca421d5b2d25e622 292 Gene3D G3DSA:1.10.10.10 109 161 1.6E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15700 d764f421c589e9ceca421d5b2d25e622 292 Pfam PF08281 Sigma-70, region 4 109 159 5.7E-6 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS15700 d764f421c589e9ceca421d5b2d25e622 292 Gene3D G3DSA:3.10.450.50 171 282 2.6E-7 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS15700 d764f421c589e9ceca421d5b2d25e622 292 SUPERFAMILY SSF54427 174 285 2.06E-11 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS15700 d764f421c589e9ceca421d5b2d25e622 292 Pfam PF04542 Sigma-70 region 2 11 74 1.7E-14 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS15700 d764f421c589e9ceca421d5b2d25e622 292 SUPERFAMILY SSF88659 103 161 1.72E-7 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS15700 d764f421c589e9ceca421d5b2d25e622 292 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 161 8.3E-15 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS10375 a56c24eeedec8d9d07cdb365ae5ad94a 875 Gene3D G3DSA:3.40.50.2000 425 724 1.7E-92 T 06-07-2017 SMD11_RS10375 a56c24eeedec8d9d07cdb365ae5ad94a 875 SUPERFAMILY SSF53756 4 749 8.97E-201 T 06-07-2017 SMD11_RS10375 a56c24eeedec8d9d07cdb365ae5ad94a 875 Gene3D G3DSA:3.40.50.2000 24 424 5.9E-91 T 06-07-2017 SMD11_RS10375 a56c24eeedec8d9d07cdb365ae5ad94a 875 Pfam PF00343 Carbohydrate phosphorylase 268 629 1.6E-18 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SMD11_RS10375 a56c24eeedec8d9d07cdb365ae5ad94a 875 Pfam PF00343 Carbohydrate phosphorylase 125 170 1.4E-6 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SMD11_RS10375 a56c24eeedec8d9d07cdb365ae5ad94a 875 Pfam PF11897 Protein of unknown function (DUF3417) 13 120 5.9E-34 T 06-07-2017 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMD11_RS10375 a56c24eeedec8d9d07cdb365ae5ad94a 875 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 607 619 - T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SMD11_RS10375 a56c24eeedec8d9d07cdb365ae5ad94a 875 PIRSF PIRSF000460 1 805 1.6E-255 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SMD11_RS10375 a56c24eeedec8d9d07cdb365ae5ad94a 875 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 107 719 2.0E-233 T 06-07-2017 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMD11_RS29460 9d73d1cb87c1f75667a3fce6e84cd66a 282 Gene3D G3DSA:1.20.120.520 36 144 2.6E-8 T 06-07-2017 SMD11_RS29460 9d73d1cb87c1f75667a3fce6e84cd66a 282 Pfam PF01814 Hemerythrin HHE cation binding domain 6 124 1.5E-12 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 SMD11_RS27610 b552db0e0a04a2acf54f3d22e76d2a57 457 Pfam PF13535 ATP-grasp domain 147 313 5.3E-8 T 06-07-2017 SMD11_RS27610 b552db0e0a04a2acf54f3d22e76d2a57 457 SUPERFAMILY SSF56059 90 347 6.75E-29 T 06-07-2017 SMD11_RS27610 b552db0e0a04a2acf54f3d22e76d2a57 457 Gene3D G3DSA:3.30.470.20 105 343 1.7E-22 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS10965 d8888d1937c72d45489e597dea66b801 841 SMART SM00387 522 653 5.3E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS10965 d8888d1937c72d45489e597dea66b801 841 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 525 651 8.9E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS10965 d8888d1937c72d45489e597dea66b801 841 Gene3D G3DSA:3.30.565.10 517 656 5.0E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS10965 d8888d1937c72d45489e597dea66b801 841 Pfam PF00672 HAMP domain 293 361 6.7E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS10965 d8888d1937c72d45489e597dea66b801 841 PRINTS PR00344 Bacterial sensor protein C-terminal signature 613 631 8.8E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS10965 d8888d1937c72d45489e597dea66b801 841 PRINTS PR00344 Bacterial sensor protein C-terminal signature 637 650 8.8E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS10965 d8888d1937c72d45489e597dea66b801 841 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 574 8.8E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS10965 d8888d1937c72d45489e597dea66b801 841 Pfam PF08376 Nitrate and nitrite sensing 57 271 2.9E-27 T 06-07-2017 IPR013587 Nitrate/nitrite sensing protein SMD11_RS10965 d8888d1937c72d45489e597dea66b801 841 SUPERFAMILY SSF55874 488 651 4.58E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS21995 1fdad72d8fb9b385889b4ff18bc5ad05 170 SUPERFAMILY SSF47598 107 154 7.94E-11 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 SMD11_RS21995 1fdad72d8fb9b385889b4ff18bc5ad05 170 Gene3D G3DSA:1.10.1220.10 109 153 3.1E-9 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMD11_RS25665 54f3dfcfc1fc136f428ca7bde1f3cc3b 170 Pfam PF14279 HNH endonuclease 84 133 1.4E-10 T 06-07-2017 IPR029471 HNH endonuclease 5 SMD11_RS25665 54f3dfcfc1fc136f428ca7bde1f3cc3b 170 SMART SM00507 71 120 1.7E-12 T 06-07-2017 IPR003615 HNH nuclease SMD11_RS30595 0b286da8dbe3828058f2ffd99f1a9fe7 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 125 5.4E-15 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS30595 0b286da8dbe3828058f2ffd99f1a9fe7 130 SUPERFAMILY SSF54593 1 127 4.3E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS30595 0b286da8dbe3828058f2ffd99f1a9fe7 130 Gene3D G3DSA:3.10.180.10 1 128 2.9E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS02760 ad6056d2f8aa9d7492617cdecd931327 143 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 34 137 8.3E-30 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD11_RS02760 ad6056d2f8aa9d7492617cdecd931327 143 Pfam PF04075 Domain of unknown function (DUF385) 16 137 1.6E-35 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD11_RS19380 cae6fe4496d63dbef01bea98505989bd 741 Pfam PF13549 ATP-grasp domain 524 736 4.8E-59 T 06-07-2017 SMD11_RS19380 cae6fe4496d63dbef01bea98505989bd 741 SUPERFAMILY SSF56059 528 738 6.51E-41 T 06-07-2017 SMD11_RS19380 cae6fe4496d63dbef01bea98505989bd 741 Pfam PF13380 CoA binding domain 61 181 3.3E-15 T 06-07-2017 IPR003781 CoA-binding GO:0048037 SMD11_RS19380 cae6fe4496d63dbef01bea98505989bd 741 Gene3D G3DSA:3.30.470.20 532 572 1.7E-5 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS19380 cae6fe4496d63dbef01bea98505989bd 741 SUPERFAMILY SSF51735 53 181 6.75E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19380 cae6fe4496d63dbef01bea98505989bd 741 Gene3D G3DSA:3.40.50.261 178 330 1.1E-15 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS19380 cae6fe4496d63dbef01bea98505989bd 741 SUPERFAMILY SSF52210 189 334 4.71E-32 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS19380 cae6fe4496d63dbef01bea98505989bd 741 SUPERFAMILY SSF52210 338 495 4.84E-26 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS19380 cae6fe4496d63dbef01bea98505989bd 741 Gene3D G3DSA:3.40.50.720 47 177 1.0E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19380 cae6fe4496d63dbef01bea98505989bd 741 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 198 332 2.9E-43 T 06-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain SMD11_RS19380 cae6fe4496d63dbef01bea98505989bd 741 SMART SM00881 56 151 4.4E-15 T 06-07-2017 IPR003781 CoA-binding GO:0048037 SMD11_RS12495 55bdcf40c05a00e63c032115db6b32c8 235 SUPERFAMILY SSF55068 25 208 6.41E-77 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SMD11_RS12495 55bdcf40c05a00e63c032115db6b32c8 235 Pfam PF01625 Peptide methionine sulfoxide reductase 50 201 2.7E-64 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SMD11_RS12495 55bdcf40c05a00e63c032115db6b32c8 235 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 49 201 3.9E-63 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SMD11_RS12495 55bdcf40c05a00e63c032115db6b32c8 235 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 46 207 36.832 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SMD11_RS12495 55bdcf40c05a00e63c032115db6b32c8 235 Gene3D G3DSA:3.30.1060.10 25 201 6.5E-76 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SMD11_RS33770 444e3e2fd202d0a04ccb1b418509e61a 207 Pfam PF00652 Ricin-type beta-trefoil lectin domain 70 202 5.1E-19 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS33770 444e3e2fd202d0a04ccb1b418509e61a 207 SUPERFAMILY SSF50370 66 204 8.13E-35 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS33770 444e3e2fd202d0a04ccb1b418509e61a 207 Gene3D G3DSA:2.80.10.50 70 205 2.7E-28 T 06-07-2017 SMD11_RS33770 444e3e2fd202d0a04ccb1b418509e61a 207 SMART SM00458 68 205 8.4E-12 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS13920 a7229726954eecf72600f9bdb6b01a15 435 Gene3D G3DSA:3.40.50.1100 218 413 9.5E-35 T 06-07-2017 SMD11_RS13920 a7229726954eecf72600f9bdb6b01a15 435 SUPERFAMILY SSF53686 18 413 1.96E-87 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS13920 a7229726954eecf72600f9bdb6b01a15 435 Gene3D G3DSA:3.40.50.1100 133 217 6.1E-28 T 06-07-2017 SMD11_RS13920 a7229726954eecf72600f9bdb6b01a15 435 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 100 403 9.2E-64 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS13920 a7229726954eecf72600f9bdb6b01a15 435 TIGRFAM TIGR00260 thrC: threonine synthase 78 408 3.5E-80 T 06-07-2017 IPR004450 Threonine synthase-like SMD11_RS16965 af42fc4b7c4330d2ca1d5c5e386c9d63 393 Pfam PF00069 Protein kinase domain 9 247 7.0E-38 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS16965 af42fc4b7c4330d2ca1d5c5e386c9d63 393 SUPERFAMILY SSF56112 5 264 9.58E-61 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS16965 af42fc4b7c4330d2ca1d5c5e386c9d63 393 SMART SM00220 9 258 9.5E-38 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS16965 af42fc4b7c4330d2ca1d5c5e386c9d63 393 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 123 135 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS16965 af42fc4b7c4330d2ca1d5c5e386c9d63 393 Gene3D G3DSA:1.10.510.10 101 254 4.8E-37 T 06-07-2017 SMD11_RS16965 af42fc4b7c4330d2ca1d5c5e386c9d63 393 Gene3D G3DSA:3.30.200.20 3 100 3.5E-18 T 06-07-2017 SMD11_RS04350 851dac57a5bc71394485d3d3eb66ef7b 249 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 242 6.7E-88 T 06-07-2017 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 SMD11_RS04350 851dac57a5bc71394485d3d3eb66ef7b 249 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMD11_RS04350 851dac57a5bc71394485d3d3eb66ef7b 249 SUPERFAMILY SSF53790 2 233 7.85E-62 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS04350 851dac57a5bc71394485d3d3eb66ef7b 249 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMD11_RS04350 851dac57a5bc71394485d3d3eb66ef7b 249 Gene3D G3DSA:3.40.1010.10 2 110 5.3E-35 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS04350 851dac57a5bc71394485d3d3eb66ef7b 249 Gene3D G3DSA:3.30.950.10 111 232 6.0E-33 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS04350 851dac57a5bc71394485d3d3eb66ef7b 249 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 208 6.1E-41 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS11025 26225248bfa0a51f849d6d25049ab846 190 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 3 127 1.3E-7 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD11_RS11025 26225248bfa0a51f849d6d25049ab846 190 SUPERFAMILY SSF109854 4 132 1.63E-9 T 06-07-2017 SMD11_RS01410 f9304c9a0c0aa0ea3256765eeb3a84a7 284 Pfam PF07859 alpha/beta hydrolase fold 41 248 3.7E-50 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SMD11_RS01410 f9304c9a0c0aa0ea3256765eeb3a84a7 284 SUPERFAMILY SSF53474 16 273 4.49E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01410 f9304c9a0c0aa0ea3256765eeb3a84a7 284 Gene3D G3DSA:3.40.50.1820 7 274 5.0E-72 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS06730 5a409196e41184e65eebfc32a0136a50 330 SUPERFAMILY SSF53850 32 50 1.38E-49 T 06-07-2017 SMD11_RS06730 5a409196e41184e65eebfc32a0136a50 330 SUPERFAMILY SSF53850 80 308 1.38E-49 T 06-07-2017 SMD11_RS06730 5a409196e41184e65eebfc32a0136a50 330 Gene3D G3DSA:3.40.190.10 275 308 1.1E-21 T 06-07-2017 SMD11_RS06730 5a409196e41184e65eebfc32a0136a50 330 Gene3D G3DSA:3.40.190.10 87 171 1.1E-21 T 06-07-2017 SMD11_RS06730 5a409196e41184e65eebfc32a0136a50 330 Gene3D G3DSA:3.40.190.10 172 274 9.7E-22 T 06-07-2017 SMD11_RS06730 5a409196e41184e65eebfc32a0136a50 330 SMART SM00062 90 314 5.4E-51 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD11_RS06730 5a409196e41184e65eebfc32a0136a50 330 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 91 308 3.5E-42 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD11_RS23645 658100317d8bef7c0753cbbe132a609b 490 SUPERFAMILY SSF50249 23 423 4.23E-87 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS23645 658100317d8bef7c0753cbbe132a609b 490 Pfam PF00773 RNB domain 54 369 3.5E-40 T 06-07-2017 SMD11_RS23645 658100317d8bef7c0753cbbe132a609b 490 SMART SM00955 52 379 7.7E-50 T 06-07-2017 SMD11_RS17945 4f6f05c343792b766b9e106e038cbe7b 85 Pfam PF11273 Protein of unknown function (DUF3073) 2 63 1.5E-20 T 06-07-2017 IPR021426 Protein of unknown function DUF3073 SMD11_RS13635 2e9e125affeedc7fdf0032ca4062b974 582 Pfam PF07287 Protein of unknown function (DUF1446) 16 351 1.7E-122 T 06-07-2017 IPR010839 Protein of unknown function DUF1446 SMD11_RS16440 fa07632505130b6210f3db98e647fec9 427 Pfam PF04261 Dyp-type peroxidase family 78 414 3.2E-102 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SMD11_RS16440 fa07632505130b6210f3db98e647fec9 427 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 78 415 6.4E-93 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SMD11_RS16440 fa07632505130b6210f3db98e647fec9 427 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 23 426 4.2E-145 T 06-07-2017 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 SMD11_RS16440 fa07632505130b6210f3db98e647fec9 427 SUPERFAMILY SSF54909 73 420 2.32E-84 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS17940 eed74651440dcf84faa9ff007cc82af7 356 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 8 339 1.1E-123 T 06-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD11_RS17940 eed74651440dcf84faa9ff007cc82af7 356 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 349 40.078 T 06-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SMD11_RS17940 eed74651440dcf84faa9ff007cc82af7 356 Gene3D G3DSA:3.90.650.10 175 346 1.3E-61 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain SMD11_RS17940 eed74651440dcf84faa9ff007cc82af7 356 SUPERFAMILY SSF56042 175 344 2.09E-52 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain SMD11_RS17940 eed74651440dcf84faa9ff007cc82af7 356 Pfam PF00586 AIR synthase related protein, N-terminal domain 63 166 2.5E-15 T 06-07-2017 IPR016188 PurM-like, N-terminal domain SMD11_RS17940 eed74651440dcf84faa9ff007cc82af7 356 SUPERFAMILY SSF55326 8 171 4.78E-43 T 06-07-2017 SMD11_RS17940 eed74651440dcf84faa9ff007cc82af7 356 Gene3D G3DSA:3.30.1330.10 23 171 9.1E-49 T 06-07-2017 IPR016188 PurM-like, N-terminal domain SMD11_RS17940 eed74651440dcf84faa9ff007cc82af7 356 Pfam PF02769 AIR synthase related protein, C-terminal domain 178 342 6.7E-31 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain SMD11_RS28555 dfb1042109e2d9d96dbb68e0fd349253 312 Pfam PF01522 Polysaccharide deacetylase 126 245 1.8E-23 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS28555 dfb1042109e2d9d96dbb68e0fd349253 312 SUPERFAMILY SSF88713 116 311 1.19E-34 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS28555 dfb1042109e2d9d96dbb68e0fd349253 312 Gene3D G3DSA:3.20.20.370 120 311 2.3E-34 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 PRINTS PR00359 B-class P450 signature 90 101 2.3E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 PRINTS PR00359 B-class P450 signature 136 152 2.3E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 PRINTS PR00359 B-class P450 signature 190 212 2.3E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 PRINTS PR00359 B-class P450 signature 319 334 2.3E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 PRINTS PR00359 B-class P450 signature 272 283 2.3E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 PRINTS PR00359 B-class P450 signature 340 349 2.3E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 PRINTS PR00359 B-class P450 signature 153 168 2.3E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 PRINTS PR00359 B-class P450 signature 349 360 2.3E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 Pfam PF00067 Cytochrome P450 81 370 2.1E-28 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 Gene3D G3DSA:1.10.630.10 3 400 7.1E-136 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 PRINTS PR00385 P450 superfamily signature 340 349 9.2E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 PRINTS PR00385 P450 superfamily signature 349 360 9.2E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 PRINTS PR00385 P450 superfamily signature 272 283 9.2E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 PRINTS PR00385 P450 superfamily signature 237 254 9.2E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20390 c4c11cfd9c0ce1089304d626bfee81fe 420 SUPERFAMILY SSF48264 7 399 1.7E-104 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS31925 80f8692005eac4cd84ace24d5f0e6a78 255 Gene3D G3DSA:3.90.230.10 3 254 7.8E-77 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS31925 80f8692005eac4cd84ace24d5f0e6a78 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 1.1E-17 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase SMD11_RS31925 80f8692005eac4cd84ace24d5f0e6a78 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 1.1E-17 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase SMD11_RS31925 80f8692005eac4cd84ace24d5f0e6a78 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 1.1E-17 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase SMD11_RS31925 80f8692005eac4cd84ace24d5f0e6a78 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 1.1E-17 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase SMD11_RS31925 80f8692005eac4cd84ace24d5f0e6a78 255 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 254 5.0E-76 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 SMD11_RS31925 80f8692005eac4cd84ace24d5f0e6a78 255 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 35.343 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 SMD11_RS31925 80f8692005eac4cd84ace24d5f0e6a78 255 Pfam PF00557 Metallopeptidase family M24 12 246 4.9E-46 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS31925 80f8692005eac4cd84ace24d5f0e6a78 255 SUPERFAMILY SSF55920 3 253 1.44E-74 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS12370 3524749ee52bd979e06ac3f70aea6c4c 104 SUPERFAMILY SSF48695 21 97 4.19E-5 T 06-07-2017 IPR011031 Multihaem cytochrome SMD11_RS12640 f919d0f8efbf3a0533bf8875171443e8 186 Gene3D G3DSA:1.10.357.10 1 183 3.3E-43 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS12640 f919d0f8efbf3a0533bf8875171443e8 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 6.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS12640 f919d0f8efbf3a0533bf8875171443e8 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 6.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS12640 f919d0f8efbf3a0533bf8875171443e8 186 SUPERFAMILY SSF46689 1 74 1.7E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS12640 f919d0f8efbf3a0533bf8875171443e8 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 5.7E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS12640 f919d0f8efbf3a0533bf8875171443e8 186 SUPERFAMILY SSF48498 76 181 8.9E-14 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS29620 3b74293018dcc84454db050a677676c7 668 Pfam PF05199 GMC oxidoreductase 487 620 6.9E-17 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS29620 3b74293018dcc84454db050a677676c7 668 Gene3D G3DSA:3.50.50.60 282 399 4.8E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29620 3b74293018dcc84454db050a677676c7 668 Gene3D G3DSA:3.50.50.60 563 629 4.8E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29620 3b74293018dcc84454db050a677676c7 668 Gene3D G3DSA:3.50.50.60 22 174 4.8E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29620 3b74293018dcc84454db050a677676c7 668 SUPERFAMILY SSF51905 566 631 1.52E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29620 3b74293018dcc84454db050a677676c7 668 SUPERFAMILY SSF51905 274 389 1.52E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29620 3b74293018dcc84454db050a677676c7 668 SUPERFAMILY SSF51905 25 183 1.52E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29620 3b74293018dcc84454db050a677676c7 668 Pfam PF00732 GMC oxidoreductase 303 382 9.6E-9 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS03350 1a8d545e1b581971ab38d97353b327f2 332 Pfam PF07859 alpha/beta hydrolase fold 81 290 2.9E-59 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SMD11_RS03350 1a8d545e1b581971ab38d97353b327f2 332 Gene3D G3DSA:3.40.50.1820 16 310 2.3E-76 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS03350 1a8d545e1b581971ab38d97353b327f2 332 SUPERFAMILY SSF53474 60 296 7.95E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS13985 6678d926919a5175a1545eb189a192b0 585 Pfam PF00989 PAS fold 234 318 2.8E-6 T 06-07-2017 IPR013767 PAS fold GO:0006355 SMD11_RS13985 6678d926919a5175a1545eb189a192b0 585 SUPERFAMILY SSF55785 201 322 1.48E-18 T 06-07-2017 IPR000014 PAS domain SMD11_RS13985 6678d926919a5175a1545eb189a192b0 585 SMART SM00086 283 325 1.8E-4 T 06-07-2017 IPR001610 PAC motif SMD11_RS13985 6678d926919a5175a1545eb189a192b0 585 SMART SM00065 29 195 9.4E-4 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS13985 6678d926919a5175a1545eb189a192b0 585 SUPERFAMILY SSF55781 13 208 1.0E-13 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS13985 6678d926919a5175a1545eb189a192b0 585 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 454 577 9.3E-29 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS13985 6678d926919a5175a1545eb189a192b0 585 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 209 331 1.1E-14 T 06-07-2017 IPR000014 PAS domain SMD11_RS13985 6678d926919a5175a1545eb189a192b0 585 SUPERFAMILY SSF55073 455 576 2.2E-35 T 06-07-2017 IPR029787 Nucleotide cyclase SMD11_RS13985 6678d926919a5175a1545eb189a192b0 585 SMART SM00091 213 283 1.2E-5 T 06-07-2017 IPR000014 PAS domain SMD11_RS13985 6678d926919a5175a1545eb189a192b0 585 Gene3D G3DSA:3.30.450.40 10 200 3.6E-15 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS13985 6678d926919a5175a1545eb189a192b0 585 Pfam PF00990 Diguanylate cyclase, GGDEF domain 455 577 2.9E-31 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS13985 6678d926919a5175a1545eb189a192b0 585 Gene3D G3DSA:3.30.70.270 338 363 2.6E-44 T 06-07-2017 SMD11_RS13985 6678d926919a5175a1545eb189a192b0 585 Gene3D G3DSA:3.30.70.270 453 577 2.6E-44 T 06-07-2017 SMD11_RS13985 6678d926919a5175a1545eb189a192b0 585 SMART SM00267 433 582 8.2E-27 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS13985 6678d926919a5175a1545eb189a192b0 585 Gene3D G3DSA:3.30.450.20 205 322 1.2E-20 T 06-07-2017 SMD11_RS13500 4a4332eb993b009cb34a79c07edc709e 241 Gene3D G3DSA:1.10.10.60 29 80 1.6E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS13500 4a4332eb993b009cb34a79c07edc709e 241 SUPERFAMILY SSF46689 28 96 1.39E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS13500 4a4332eb993b009cb34a79c07edc709e 241 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 83 3.4E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS13500 4a4332eb993b009cb34a79c07edc709e 241 Gene3D G3DSA:1.10.357.10 81 219 1.8E-8 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS13500 4a4332eb993b009cb34a79c07edc709e 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 61 84 1.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS13500 4a4332eb993b009cb34a79c07edc709e 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 53 1.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS13450 c67be578c0f2eb20f1981ecc55b6cd57 184 Gene3D G3DSA:3.40.1410.10 25 179 3.2E-39 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS13450 c67be578c0f2eb20f1981ecc55b6cd57 184 Pfam PF07702 UTRA domain 41 170 3.6E-25 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS13450 c67be578c0f2eb20f1981ecc55b6cd57 184 SMART SM00866 35 176 2.3E-20 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS13450 c67be578c0f2eb20f1981ecc55b6cd57 184 SUPERFAMILY SSF64288 30 180 1.01E-31 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS06545 3e001d415d0b6902a74959736acb3e72 256 Gene3D G3DSA:3.40.50.1220 19 34 1.2E-40 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS06545 3e001d415d0b6902a74959736acb3e72 256 Gene3D G3DSA:3.40.50.1220 86 125 1.2E-40 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS06545 3e001d415d0b6902a74959736acb3e72 256 Gene3D G3DSA:3.40.50.1220 180 252 1.2E-40 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS06545 3e001d415d0b6902a74959736acb3e72 256 SUPERFAMILY SSF52467 19 252 1.18E-73 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS06545 3e001d415d0b6902a74959736acb3e72 256 Gene3D G3DSA:3.30.1600.10 35 74 1.3E-23 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain SMD11_RS06545 3e001d415d0b6902a74959736acb3e72 256 Gene3D G3DSA:3.30.1600.10 126 173 1.3E-23 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain SMD11_RS06545 3e001d415d0b6902a74959736acb3e72 256 Pfam PF02146 Sir2 family 24 204 1.2E-45 T 06-07-2017 IPR003000 Sirtuin family GO:0070403 SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 86 132 3.3E-13 T 06-07-2017 IPR011096 FTP domain SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 SUPERFAMILY SSF49785 653 760 1.57E-21 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 Gene3D G3DSA:2.60.40.10 562 643 4.0E-11 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 SUPERFAMILY SSF49313 561 643 8.95E-13 T 06-07-2017 IPR015919 Cadherin-like GO:0005509|GO:0016020 SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 377 551 7.6E-49 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 227 374 3.5E-48 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 Pfam PF05345 Putative Ig domain 590 630 1.1E-11 T 06-07-2017 IPR008009 Putative Ig SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 Gene3D G3DSA:2.60.120.260 682 760 7.4E-16 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 Pfam PF01483 Proprotein convertase P-domain 680 760 6.0E-20 T 06-07-2017 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 SUPERFAMILY SSF55486 226 552 3.85E-77 T 06-07-2017 SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 453 469 4.6E-15 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 365 381 4.6E-15 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 386 397 4.6E-15 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 329 349 4.6E-15 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 Gene3D G3DSA:1.10.390.10 379 551 4.8E-47 T 06-07-2017 SMD11_RS10370 60cc0ad12d1dc336f4aa7d54af2aed76 760 Gene3D G3DSA:3.10.170.10 227 378 7.7E-46 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS33305 cedca310def034d6be233524ab47c8e8 196 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 15 61 2.3E-9 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS33305 cedca310def034d6be233524ab47c8e8 196 SUPERFAMILY SSF47741 93 182 7.85E-28 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD11_RS33305 cedca310def034d6be233524ab47c8e8 196 Pfam PF01799 [2Fe-2S] binding domain 82 172 2.8E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD11_RS33305 cedca310def034d6be233524ab47c8e8 196 Gene3D G3DSA:1.10.150.120 84 190 1.2E-32 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD11_RS33305 cedca310def034d6be233524ab47c8e8 196 Gene3D G3DSA:3.10.20.30 10 83 6.3E-31 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS33305 cedca310def034d6be233524ab47c8e8 196 SUPERFAMILY SSF54292 10 96 3.01E-26 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS33305 cedca310def034d6be233524ab47c8e8 196 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 48 56 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMD11_RS11470 c32fd688b763bba85c8c43f1276743cf 138 Pfam PF01475 Ferric uptake regulator family 11 103 1.6E-24 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 SMD11_RS11470 c32fd688b763bba85c8c43f1276743cf 138 Gene3D G3DSA:1.10.10.10 2 82 1.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11470 c32fd688b763bba85c8c43f1276743cf 138 SUPERFAMILY SSF46785 3 134 8.5E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19485 c895e76e84cc4447a2c6ec6c3386d291 354 SUPERFAMILY SSF53335 81 281 1.32E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS19485 c895e76e84cc4447a2c6ec6c3386d291 354 Pfam PF13489 Methyltransferase domain 107 266 5.8E-21 T 06-07-2017 SMD11_RS19485 c895e76e84cc4447a2c6ec6c3386d291 354 Gene3D G3DSA:3.40.50.150 108 272 6.1E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29750 72de3eae73494ae3104df7d094242d77 489 Pfam PF07730 Histidine kinase 277 351 1.9E-5 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS29750 72de3eae73494ae3104df7d094242d77 489 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 392 482 3.7E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS29750 72de3eae73494ae3104df7d094242d77 489 Gene3D G3DSA:3.30.565.10 374 482 1.1E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS29750 72de3eae73494ae3104df7d094242d77 489 SMART SM00387 389 483 3.6E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS29750 72de3eae73494ae3104df7d094242d77 489 SUPERFAMILY SSF55874 358 481 3.27E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 213 226 5.5E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 403 416 5.5E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 79 97 5.5E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 99 111 5.5E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 302 321 5.5E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 Gene3D G3DSA:2.40.37.10 299 445 1.4E-44 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 39 446 37.944 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 Gene3D G3DSA:3.20.20.10 58 298 8.7E-78 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 60 312 2.4E-53 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 PRINTS PR01181 Diaminopimelate decarboxylase signature 330 348 6.0E-23 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 PRINTS PR01181 Diaminopimelate decarboxylase signature 185 194 6.0E-23 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 PRINTS PR01181 Diaminopimelate decarboxylase signature 413 435 6.0E-23 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 PRINTS PR01181 Diaminopimelate decarboxylase signature 97 114 6.0E-23 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 319 421 3.1E-14 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 SUPERFAMILY SSF50621 289 445 1.03E-48 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 79 97 - T 06-07-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 33 444 1.3E-123 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS07015 218f772f6fb98e91bafea500fc38bde0 448 SUPERFAMILY SSF51419 50 314 4.94E-69 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS07825 9e6774246a4abc9803b192d264741330 490 Gene3D G3DSA:1.20.1250.20 259 470 5.4E-27 T 06-07-2017 SMD11_RS07825 9e6774246a4abc9803b192d264741330 490 SUPERFAMILY SSF103473 253 466 1.96E-69 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS07825 9e6774246a4abc9803b192d264741330 490 SUPERFAMILY SSF103473 14 203 1.96E-69 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS07825 9e6774246a4abc9803b192d264741330 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 5.9E-8 T 06-07-2017 SMD11_RS07825 9e6774246a4abc9803b192d264741330 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 114 134 5.9E-8 T 06-07-2017 SMD11_RS07825 9e6774246a4abc9803b192d264741330 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 307 331 5.9E-8 T 06-07-2017 SMD11_RS07825 9e6774246a4abc9803b192d264741330 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 23 47 5.9E-8 T 06-07-2017 SMD11_RS07825 9e6774246a4abc9803b192d264741330 490 Gene3D G3DSA:1.20.1250.20 18 197 1.4E-28 T 06-07-2017 SMD11_RS07825 9e6774246a4abc9803b192d264741330 490 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 20 424 3.7E-91 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS07825 9e6774246a4abc9803b192d264741330 490 Pfam PF07690 Major Facilitator Superfamily 26 415 6.7E-50 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS05255 6c04937f8cf1cb75fdf82e81fe2a7c80 396 Pfam PF12706 Beta-lactamase superfamily domain 113 314 9.0E-51 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS05255 6c04937f8cf1cb75fdf82e81fe2a7c80 396 SUPERFAMILY SSF56281 96 173 1.13E-33 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS05255 6c04937f8cf1cb75fdf82e81fe2a7c80 396 SUPERFAMILY SSF56281 201 351 1.13E-33 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS05255 6c04937f8cf1cb75fdf82e81fe2a7c80 396 Gene3D G3DSA:3.60.15.10 83 364 2.1E-104 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS33395 c763d1f5544de9611d2a3401b5e53173 507 SUPERFAMILY SSF51658 255 443 4.56E-13 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS33395 c763d1f5544de9611d2a3401b5e53173 507 Pfam PF05114 Protein of unknown function (DUF692) 235 496 4.2E-104 T 06-07-2017 IPR007801 Uncharacterised protein family UPF0276 SMD11_RS33395 c763d1f5544de9611d2a3401b5e53173 507 Gene3D G3DSA:3.20.20.150 233 498 1.9E-100 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS33395 c763d1f5544de9611d2a3401b5e53173 507 Hamap MF_00697 UPF0276 protein . 236 504 43.471 T 06-07-2017 IPR007801 Uncharacterised protein family UPF0276 SMD11_RS18260 9122d401c858fb4149c455ad4d98ec27 268 SUPERFAMILY SSF88659 193 263 1.78E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS18260 9122d401c858fb4149c455ad4d98ec27 268 Gene3D G3DSA:1.10.10.10 202 264 7.4E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS18260 9122d401c858fb4149c455ad4d98ec27 268 TIGRFAM TIGR02952 Sig70_famx2: RNA polymerase sigma-70 factor, TIGR02952 family 94 263 5.0E-78 T 06-07-2017 IPR014298 RNA polymerase sigma-X type SMD11_RS18260 9122d401c858fb4149c455ad4d98ec27 268 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 104 261 2.3E-29 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS18260 9122d401c858fb4149c455ad4d98ec27 268 Pfam PF08281 Sigma-70, region 4 208 259 5.8E-14 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS18260 9122d401c858fb4149c455ad4d98ec27 268 Gene3D G3DSA:1.10.1740.10 92 201 4.8E-29 T 06-07-2017 SMD11_RS18260 9122d401c858fb4149c455ad4d98ec27 268 Pfam PF04542 Sigma-70 region 2 109 176 1.1E-17 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS18260 9122d401c858fb4149c455ad4d98ec27 268 SUPERFAMILY SSF88946 87 195 7.65E-27 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS15225 e3afb94a383bae3420ff0e072d3d16e7 150 Gene3D G3DSA:2.40.50.140 6 112 2.1E-35 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS15225 e3afb94a383bae3420ff0e072d3d16e7 150 Hamap MF_00984 Single-stranded DNA-binding protein. 5 114 26.696 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SMD11_RS15225 e3afb94a383bae3420ff0e072d3d16e7 150 SUPERFAMILY SSF50249 8 150 2.45E-36 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS15225 e3afb94a383bae3420ff0e072d3d16e7 150 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 8 121 5.2E-27 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SMD11_RS15225 e3afb94a383bae3420ff0e072d3d16e7 150 Pfam PF00436 Single-strand binding protein family 8 107 5.3E-26 T 06-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 SMD11_RS13245 5ae3f8ff11da8bd8e72d60fc7c9dab52 392 Pfam PF08442 ATP-grasp domain 2 195 5.1E-68 T 06-07-2017 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD11_RS13245 5ae3f8ff11da8bd8e72d60fc7c9dab52 392 Gene3D G3DSA:3.30.1490.20 22 85 1.5E-17 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS13245 5ae3f8ff11da8bd8e72d60fc7c9dab52 392 Gene3D G3DSA:3.30.470.20 86 229 1.3E-49 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS13245 5ae3f8ff11da8bd8e72d60fc7c9dab52 392 SUPERFAMILY SSF56059 3 227 3.72E-62 T 06-07-2017 SMD11_RS13245 5ae3f8ff11da8bd8e72d60fc7c9dab52 392 Pfam PF00549 CoA-ligase 257 376 8.6E-14 T 06-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS13245 5ae3f8ff11da8bd8e72d60fc7c9dab52 392 PIRSF PIRSF001554 1 392 8.9E-136 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD11_RS13245 5ae3f8ff11da8bd8e72d60fc7c9dab52 392 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 389 4.4E-122 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD11_RS13245 5ae3f8ff11da8bd8e72d60fc7c9dab52 392 SUPERFAMILY SSF52210 232 389 2.88E-42 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS13245 5ae3f8ff11da8bd8e72d60fc7c9dab52 392 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 250 274 - T 06-07-2017 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS13245 5ae3f8ff11da8bd8e72d60fc7c9dab52 392 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 390 40.545 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD11_RS13245 5ae3f8ff11da8bd8e72d60fc7c9dab52 392 Gene3D G3DSA:3.40.50.261 233 389 7.1E-53 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 SMD11_RS29850 e30e4c7514c4ad697963c89945cbac1e 77 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 6 66 5.3E-16 T 06-07-2017 IPR032716 Acyl-CoA carboxylase epsilon subunit SMD11_RS07185 49f120cf60dd28331ed83acee31edec7 198 SUPERFAMILY SSF55729 59 182 5.06E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS07185 49f120cf60dd28331ed83acee31edec7 198 Pfam PF13508 Acetyltransferase (GNAT) domain 84 174 2.6E-7 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS07185 49f120cf60dd28331ed83acee31edec7 198 Gene3D G3DSA:3.40.630.30 63 181 2.7E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS29845 ed6d593e963ab23f5277cffc6c8a4921 533 SUPERFAMILY SSF52096 20 273 2.93E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS29845 ed6d593e963ab23f5277cffc6c8a4921 533 Pfam PF01039 Carboxyl transferase domain 45 530 6.2E-191 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS29845 ed6d593e963ab23f5277cffc6c8a4921 533 Gene3D G3DSA:3.90.226.10 16 272 2.2E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS29845 ed6d593e963ab23f5277cffc6c8a4921 533 SUPERFAMILY SSF52096 271 533 2.11E-86 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS29845 ed6d593e963ab23f5277cffc6c8a4921 533 Gene3D G3DSA:3.90.226.10 273 532 4.9E-98 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS20190 1e82276c7322a7c742c2db45f55a706f 168 Pfam PF14433 SUKH-3 immunity protein 12 156 2.0E-48 T 06-07-2017 IPR025850 SUKH-3 immunity protein SMD11_RS03110 4c2482e237559c35e5b8a4b9338da2b7 280 Pfam PF03476 MOSC N-terminal beta barrel domain 6 120 1.5E-25 T 06-07-2017 IPR005303 MOSC, N-terminal beta barrel SMD11_RS03110 4c2482e237559c35e5b8a4b9338da2b7 280 Pfam PF03473 MOSC domain 147 274 3.1E-30 T 06-07-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 SMD11_RS03110 4c2482e237559c35e5b8a4b9338da2b7 280 SUPERFAMILY SSF50800 159 276 6.8E-19 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain SMD11_RS03110 4c2482e237559c35e5b8a4b9338da2b7 280 SUPERFAMILY SSF50800 4 52 6.8E-19 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain SMD11_RS03110 4c2482e237559c35e5b8a4b9338da2b7 280 SUPERFAMILY SSF141673 6 135 6.54E-32 T 06-07-2017 SMD11_RS03945 d378133a30c1b6fd5ec00bab2b1b9f9e 259 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 245 39.705 T 06-07-2017 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 KEGG: 00311+3.5.1.11|KEGG: 00340+3.5.1.118|MetaCyc: PWY-7255 SMD11_RS03945 d378133a30c1b6fd5ec00bab2b1b9f9e 259 Gene3D G3DSA:3.60.20.10 1 242 2.9E-40 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS03945 d378133a30c1b6fd5ec00bab2b1b9f9e 259 SUPERFAMILY SSF56235 2 247 2.83E-16 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS03945 d378133a30c1b6fd5ec00bab2b1b9f9e 259 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 245 1.0E-84 T 06-07-2017 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 SMD11_RS03945 d378133a30c1b6fd5ec00bab2b1b9f9e 259 Pfam PF13522 Glutamine amidotransferase domain 70 216 9.4E-15 T 06-07-2017 SMD11_RS08920 5e5ea83b8c8554af4f0f23bc988a75bc 216 SUPERFAMILY SSF161098 11 204 7.59E-35 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS08920 5e5ea83b8c8554af4f0f23bc988a75bc 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 106 3.8E-19 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMD11_RS08920 5e5ea83b8c8554af4f0f23bc988a75bc 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 212 4.3E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS08920 5e5ea83b8c8554af4f0f23bc988a75bc 216 Gene3D G3DSA:1.10.3720.10 7 212 6.3E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21805 0f31decbbc988b28e8b98590398a6dcd 267 Pfam PF01261 Xylose isomerase-like TIM barrel 20 211 2.1E-26 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS21805 0f31decbbc988b28e8b98590398a6dcd 267 SUPERFAMILY SSF51658 1 244 5.53E-45 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS21805 0f31decbbc988b28e8b98590398a6dcd 267 Gene3D G3DSA:3.20.20.150 1 241 1.8E-57 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS13740 2c8a2e7926285e060df65d29cc3f003b 229 Gene3D G3DSA:3.40.50.1110 1 217 7.5E-24 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS13740 2c8a2e7926285e060df65d29cc3f003b 229 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 5 203 2.3E-16 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS13740 2c8a2e7926285e060df65d29cc3f003b 229 SUPERFAMILY SSF52266 1 38 4.73E-23 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS13740 2c8a2e7926285e060df65d29cc3f003b 229 SUPERFAMILY SSF52266 69 218 4.73E-23 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS30270 43cb106b78b3a77eaabfd4d275c7e8bb 278 SUPERFAMILY SSF53474 22 219 5.3E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30270 43cb106b78b3a77eaabfd4d275c7e8bb 278 Gene3D G3DSA:3.40.50.1820 11 275 3.9E-68 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30270 43cb106b78b3a77eaabfd4d275c7e8bb 278 Pfam PF01674 Lipase (class 2) 28 214 8.4E-16 T 06-07-2017 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 SMD11_RS17935 15c23368b7ad07d87d2e88e91f3c7009 505 Pfam PF13522 Glutamine amidotransferase domain 85 227 1.1E-15 T 06-07-2017 SMD11_RS17935 15c23368b7ad07d87d2e88e91f3c7009 505 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 23 474 2.1E-158 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 SMD11_RS17935 15c23368b7ad07d87d2e88e91f3c7009 505 Pfam PF00156 Phosphoribosyl transferase domain 302 403 2.4E-6 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMD11_RS17935 15c23368b7ad07d87d2e88e91f3c7009 505 Gene3D G3DSA:3.60.20.10 23 274 9.6E-68 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS17935 15c23368b7ad07d87d2e88e91f3c7009 505 PIRSF PIRSF000485 19 485 4.6E-161 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 SMD11_RS17935 15c23368b7ad07d87d2e88e91f3c7009 505 Gene3D G3DSA:3.40.50.2020 290 456 2.6E-44 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS17935 15c23368b7ad07d87d2e88e91f3c7009 505 SUPERFAMILY SSF56235 23 286 1.37E-64 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS17935 15c23368b7ad07d87d2e88e91f3c7009 505 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 22 475 46.675 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 SMD11_RS17935 15c23368b7ad07d87d2e88e91f3c7009 505 SUPERFAMILY SSF53271 268 482 1.23E-68 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS07355 b2ee8d7ff29456fb8b07722b3b012b40 388 Pfam PF03969 AFG1-like ATPase 279 379 8.8E-15 T 06-07-2017 IPR005654 ATPase, AFG1-like GO:0005524 SMD11_RS07355 b2ee8d7ff29456fb8b07722b3b012b40 388 Pfam PF03969 AFG1-like ATPase 56 268 1.9E-42 T 06-07-2017 IPR005654 ATPase, AFG1-like GO:0005524 SMD11_RS07355 b2ee8d7ff29456fb8b07722b3b012b40 388 SUPERFAMILY SSF52540 117 231 7.1E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07355 b2ee8d7ff29456fb8b07722b3b012b40 388 Gene3D G3DSA:3.40.50.300 58 249 3.1E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS33540 e30f4bb667a7da610258672344a724af 304 Gene3D G3DSA:3.40.190.10 91 178 2.3E-22 T 06-07-2017 SMD11_RS33540 e30f4bb667a7da610258672344a724af 304 SUPERFAMILY SSF46785 4 88 4.36E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33540 e30f4bb667a7da610258672344a724af 304 Pfam PF03466 LysR substrate binding domain 89 295 3.5E-36 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS33540 e30f4bb667a7da610258672344a724af 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS33540 e30f4bb667a7da610258672344a724af 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS33540 e30f4bb667a7da610258672344a724af 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS33540 e30f4bb667a7da610258672344a724af 304 Gene3D G3DSA:1.10.10.10 4 87 6.4E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33540 e30f4bb667a7da610258672344a724af 304 SUPERFAMILY SSF53850 90 297 1.09E-32 T 06-07-2017 SMD11_RS33540 e30f4bb667a7da610258672344a724af 304 Gene3D G3DSA:3.40.190.10 179 267 1.5E-22 T 06-07-2017 SMD11_RS33540 e30f4bb667a7da610258672344a724af 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.6E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS12000 9333e8a7cdfa1dd5b4c0979a2aeeede2 307 Gene3D G3DSA:1.10.3720.10 89 302 1.8E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS12000 9333e8a7cdfa1dd5b4c0979a2aeeede2 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 1.7E-35 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS12000 9333e8a7cdfa1dd5b4c0979a2aeeede2 307 SUPERFAMILY SSF161098 90 288 5.63E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS12180 17cf91f61f3d114e734583c039153c0d 464 SUPERFAMILY SSF48557 7 462 2.2E-147 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 SMD11_RS12180 17cf91f61f3d114e734583c039153c0d 464 Pfam PF00206 Lyase 15 339 4.7E-102 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal SMD11_RS12180 17cf91f61f3d114e734583c039153c0d 464 ProSitePatterns PS00163 Fumarate lyases signature. 314 323 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 SMD11_RS12180 17cf91f61f3d114e734583c039153c0d 464 PRINTS PR00145 Argininosuccinate lyase family signature 172 192 9.0E-6 T 06-07-2017 SMD11_RS12180 17cf91f61f3d114e734583c039153c0d 464 PRINTS PR00145 Argininosuccinate lyase family signature 314 330 9.0E-6 T 06-07-2017 SMD11_RS12180 17cf91f61f3d114e734583c039153c0d 464 Hamap MF_00743 Fumarate hydratase class II [fumC]. 7 464 81.947 T 06-07-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD11_RS12180 17cf91f61f3d114e734583c039153c0d 464 PRINTS PR00149 Fumarate lyase superfamily signature 314 330 8.1E-33 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS12180 17cf91f61f3d114e734583c039153c0d 464 PRINTS PR00149 Fumarate lyase superfamily signature 268 295 8.1E-33 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS12180 17cf91f61f3d114e734583c039153c0d 464 PRINTS PR00149 Fumarate lyase superfamily signature 131 149 8.1E-33 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS12180 17cf91f61f3d114e734583c039153c0d 464 PRINTS PR00149 Fumarate lyase superfamily signature 177 195 8.1E-33 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS12180 17cf91f61f3d114e734583c039153c0d 464 Gene3D G3DSA:1.10.40.30 405 464 6.4E-23 T 06-07-2017 SMD11_RS12180 17cf91f61f3d114e734583c039153c0d 464 Pfam PF10415 Fumarase C C-terminus 405 463 1.6E-22 T 06-07-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 SMD11_RS12180 17cf91f61f3d114e734583c039153c0d 464 Gene3D G3DSA:1.10.275.10 6 135 2.8E-53 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal SMD11_RS12180 17cf91f61f3d114e734583c039153c0d 464 Gene3D G3DSA:1.20.200.10 136 400 2.7E-96 T 06-07-2017 SMD11_RS04295 bf12342551a0770d52add9078d1fce47 249 SUPERFAMILY SSF51735 1 248 1.77E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04295 bf12342551a0770d52add9078d1fce47 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS04295 bf12342551a0770d52add9078d1fce47 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS04295 bf12342551a0770d52add9078d1fce47 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS04295 bf12342551a0770d52add9078d1fce47 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS04295 bf12342551a0770d52add9078d1fce47 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 195 0.005 T 06-07-2017 SMD11_RS04295 bf12342551a0770d52add9078d1fce47 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 247 4.9E-54 T 06-07-2017 SMD11_RS04295 bf12342551a0770d52add9078d1fce47 249 Gene3D G3DSA:3.40.50.720 3 249 3.1E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04295 bf12342551a0770d52add9078d1fce47 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.8E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS04295 bf12342551a0770d52add9078d1fce47 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 4.8E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS04295 bf12342551a0770d52add9078d1fce47 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.8E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS04295 bf12342551a0770d52add9078d1fce47 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 4.8E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS04295 bf12342551a0770d52add9078d1fce47 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 4.8E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS04295 bf12342551a0770d52add9078d1fce47 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 4.8E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS14255 f89119fcca272dd15426462c7afe209c 115 Gene3D G3DSA:1.10.10.10 5 78 2.6E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14255 f89119fcca272dd15426462c7afe209c 115 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 6.6E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS14255 f89119fcca272dd15426462c7afe209c 115 SMART SM00345 18 77 4.4E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS14255 f89119fcca272dd15426462c7afe209c 115 SUPERFAMILY SSF46785 7 80 3.01E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06670 b20973281859afddb3a888afbf868864 349 SMART SM00429 259 340 1.0 T 06-07-2017 IPR002909 IPT domain GO:0005515 SMD11_RS06670 b20973281859afddb3a888afbf868864 349 SMART SM00429 173 250 3.7E-4 T 06-07-2017 IPR002909 IPT domain GO:0005515 SMD11_RS06670 b20973281859afddb3a888afbf868864 349 Gene3D G3DSA:2.60.40.10 173 249 6.5E-9 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS06670 b20973281859afddb3a888afbf868864 349 Pfam PF01833 IPT/TIG domain 174 249 6.9E-6 T 06-07-2017 IPR002909 IPT domain GO:0005515 SMD11_RS06670 b20973281859afddb3a888afbf868864 349 SUPERFAMILY SSF81296 173 247 6.62E-6 T 06-07-2017 IPR014756 Immunoglobulin E-set SMD11_RS06670 b20973281859afddb3a888afbf868864 349 Gene3D G3DSA:2.60.40.10 258 343 9.9E-6 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS14865 64261f59a644e613f2b0185ad8999726 360 SUPERFAMILY SSF46785 276 351 2.04E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14865 64261f59a644e613f2b0185ad8999726 360 Pfam PF12840 Helix-turn-helix domain 278 336 3.8E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14865 64261f59a644e613f2b0185ad8999726 360 Gene3D G3DSA:1.10.10.10 276 356 8.1E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14865 64261f59a644e613f2b0185ad8999726 360 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 312 327 6.6E-9 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS14865 64261f59a644e613f2b0185ad8999726 360 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 327 342 6.6E-9 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS14865 64261f59a644e613f2b0185ad8999726 360 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 280 295 6.6E-9 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS14865 64261f59a644e613f2b0185ad8999726 360 SMART SM00418 278 356 7.5E-24 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS14245 ea80b53e8f09bfd424b4b79d8e9cbb7c 312 SMART SM00382 37 229 3.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS14245 ea80b53e8f09bfd424b4b79d8e9cbb7c 312 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS14245 ea80b53e8f09bfd424b4b79d8e9cbb7c 312 Gene3D G3DSA:3.40.50.300 8 229 1.6E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14245 ea80b53e8f09bfd424b4b79d8e9cbb7c 312 Pfam PF00005 ABC transporter 28 166 7.6E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS14245 ea80b53e8f09bfd424b4b79d8e9cbb7c 312 SUPERFAMILY SSF52540 12 229 1.58E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17795 b23673ef8fa24454e3002a5b751276e8 67 PRINTS PR00050 Cold shock protein signature 40 58 6.9E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS17795 b23673ef8fa24454e3002a5b751276e8 67 PRINTS PR00050 Cold shock protein signature 4 19 6.9E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS17795 b23673ef8fa24454e3002a5b751276e8 67 PRINTS PR00050 Cold shock protein signature 25 34 6.9E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS17795 b23673ef8fa24454e3002a5b751276e8 67 SUPERFAMILY SSF50249 2 66 9.21E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS17795 b23673ef8fa24454e3002a5b751276e8 67 PIRSF PIRSF002599 1 67 7.0E-26 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 SMD11_RS17795 b23673ef8fa24454e3002a5b751276e8 67 SMART SM00357 3 67 8.6E-32 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 SMD11_RS17795 b23673ef8fa24454e3002a5b751276e8 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site SMD11_RS17795 b23673ef8fa24454e3002a5b751276e8 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.5E-31 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS17795 b23673ef8fa24454e3002a5b751276e8 67 Gene3D G3DSA:2.40.50.140 2 65 1.2E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS29475 fe35ae49e358e42d5c3844aa9fa46a11 793 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 16 270 2.5E-62 T 06-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 SMD11_RS29475 fe35ae49e358e42d5c3844aa9fa46a11 793 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 327 694 1.6E-129 T 06-07-2017 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 SMD11_RS29475 fe35ae49e358e42d5c3844aa9fa46a11 793 SUPERFAMILY SSF74650 6 270 9.1E-67 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMD11_RS29475 fe35ae49e358e42d5c3844aa9fa46a11 793 Gene3D G3DSA:2.70.98.40 6 270 7.7E-76 T 06-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 SMD11_RS29475 fe35ae49e358e42d5c3844aa9fa46a11 793 PIRSF PIRSF036289 1 761 2.6E-212 T 06-07-2017 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase SMD11_RS29475 fe35ae49e358e42d5c3844aa9fa46a11 793 Gene3D G3DSA:2.60.420.10 683 753 1.7E-19 T 06-07-2017 SMD11_RS29475 fe35ae49e358e42d5c3844aa9fa46a11 793 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 700 749 3.4E-13 T 06-07-2017 IPR005194 Glycoside hydrolase family 65, C-terminal SMD11_RS29475 fe35ae49e358e42d5c3844aa9fa46a11 793 SUPERFAMILY SSF48208 278 743 6.24E-115 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD11_RS29475 fe35ae49e358e42d5c3844aa9fa46a11 793 Gene3D G3DSA:1.50.10.10 321 682 2.2E-124 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 SMD11_RS32520 0cd44f9ef559a1725a8e3ee2e2f743c2 528 Pfam PF01425 Amidase 67 499 8.1E-108 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS32520 0cd44f9ef559a1725a8e3ee2e2f743c2 528 Gene3D G3DSA:3.90.1300.10 44 518 4.5E-139 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS32520 0cd44f9ef559a1725a8e3ee2e2f743c2 528 SUPERFAMILY SSF75304 45 515 5.49E-115 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS12275 5b9e4a726b3deb4e50713b52c7d475ed 242 Pfam PF01478 Type IV leader peptidase family 94 200 9.5E-15 T 06-07-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 SMD11_RS12275 5b9e4a726b3deb4e50713b52c7d475ed 242 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 159 169 9.8E-6 T 06-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial SMD11_RS12275 5b9e4a726b3deb4e50713b52c7d475ed 242 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 170 181 9.8E-6 T 06-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial SMD11_RS12275 5b9e4a726b3deb4e50713b52c7d475ed 242 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 102 119 9.8E-6 T 06-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial SMD11_RS28345 bd9c0286136a50a8e963d78c702bfaad 900 Gene3D G3DSA:3.40.50.300 25 88 6.9E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28345 bd9c0286136a50a8e963d78c702bfaad 900 Gene3D G3DSA:3.40.50.300 138 205 6.9E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28345 bd9c0286136a50a8e963d78c702bfaad 900 Pfam PF13181 Tetratricopeptide repeat 651 676 0.069 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS28345 bd9c0286136a50a8e963d78c702bfaad 900 Pfam PF13191 AAA ATPase domain 14 187 7.9E-20 T 06-07-2017 SMD11_RS28345 bd9c0286136a50a8e963d78c702bfaad 900 SUPERFAMILY SSF48452 610 679 3.11E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS28345 bd9c0286136a50a8e963d78c702bfaad 900 SUPERFAMILY SSF48452 726 762 3.11E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS28345 bd9c0286136a50a8e963d78c702bfaad 900 SUPERFAMILY SSF48452 819 868 3.11E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS28345 bd9c0286136a50a8e963d78c702bfaad 900 SUPERFAMILY SSF52540 131 266 1.09E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28345 bd9c0286136a50a8e963d78c702bfaad 900 SUPERFAMILY SSF52540 39 69 1.09E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28345 bd9c0286136a50a8e963d78c702bfaad 900 Gene3D G3DSA:1.25.40.10 478 505 4.3E-24 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS28345 bd9c0286136a50a8e963d78c702bfaad 900 Gene3D G3DSA:1.25.40.10 720 894 4.3E-24 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS28345 bd9c0286136a50a8e963d78c702bfaad 900 Gene3D G3DSA:1.25.40.10 575 679 4.3E-24 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS28345 bd9c0286136a50a8e963d78c702bfaad 900 Gene3D G3DSA:1.25.40.10 403 442 4.3E-24 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS14285 8c207374fd7d0037ef9f575bbe1abb58 377 Gene3D G3DSA:2.40.10.10 158 234 1.6E-30 T 06-07-2017 SMD11_RS14285 8c207374fd7d0037ef9f575bbe1abb58 377 PRINTS PR00834 HtrA/DegQ protease family signature 172 184 1.6E-26 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS14285 8c207374fd7d0037ef9f575bbe1abb58 377 PRINTS PR00834 HtrA/DegQ protease family signature 193 213 1.6E-26 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS14285 8c207374fd7d0037ef9f575bbe1abb58 377 PRINTS PR00834 HtrA/DegQ protease family signature 305 322 1.6E-26 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS14285 8c207374fd7d0037ef9f575bbe1abb58 377 PRINTS PR00834 HtrA/DegQ protease family signature 327 344 1.6E-26 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SMD11_RS14285 8c207374fd7d0037ef9f575bbe1abb58 377 Gene3D G3DSA:2.40.10.10 305 374 3.0E-39 T 06-07-2017 SMD11_RS14285 8c207374fd7d0037ef9f575bbe1abb58 377 Gene3D G3DSA:2.40.10.10 235 268 3.0E-39 T 06-07-2017 SMD11_RS14285 8c207374fd7d0037ef9f575bbe1abb58 377 SUPERFAMILY SSF50494 303 374 1.16E-53 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS14285 8c207374fd7d0037ef9f575bbe1abb58 377 SUPERFAMILY SSF50494 140 266 1.16E-53 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS14285 8c207374fd7d0037ef9f575bbe1abb58 377 Pfam PF13365 Trypsin-like peptidase domain 163 334 2.3E-30 T 06-07-2017 SMD11_RS10540 9dbd51bcb9ba05fe71c5116d9a8eb136 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 1.7E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS10540 9dbd51bcb9ba05fe71c5116d9a8eb136 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 1.7E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS10540 9dbd51bcb9ba05fe71c5116d9a8eb136 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.7E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS10540 9dbd51bcb9ba05fe71c5116d9a8eb136 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.7E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS10540 9dbd51bcb9ba05fe71c5116d9a8eb136 145 Pfam PF12802 MarR family 32 93 5.6E-13 T 06-07-2017 SMD11_RS10540 9dbd51bcb9ba05fe71c5116d9a8eb136 145 SUPERFAMILY SSF46785 17 142 6.96E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS10540 9dbd51bcb9ba05fe71c5116d9a8eb136 145 Gene3D G3DSA:1.10.10.10 7 142 1.1E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS10540 9dbd51bcb9ba05fe71c5116d9a8eb136 145 SMART SM00347 27 130 8.1E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS28725 50fa7c8e635d902f473bbc91b9b32837 167 SMART SM00987 1 160 1.2E-8 T 06-07-2017 SMD11_RS28725 50fa7c8e635d902f473bbc91b9b32837 167 Gene3D G3DSA:3.40.470.10 2 162 2.6E-58 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS28725 50fa7c8e635d902f473bbc91b9b32837 167 Pfam PF03167 Uracil DNA glycosylase superfamily 6 157 9.1E-27 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS28725 50fa7c8e635d902f473bbc91b9b32837 167 SMART SM00986 1 160 1.2E-8 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS28725 50fa7c8e635d902f473bbc91b9b32837 167 SUPERFAMILY SSF52141 3 160 6.87E-46 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS18120 7657b3ff3199c4833d5c530284e565a4 741 SUPERFAMILY SSF56235 25 208 2.35E-11 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS18120 7657b3ff3199c4833d5c530284e565a4 741 Pfam PF00733 Asparagine synthase 283 710 1.6E-11 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMD11_RS18120 7657b3ff3199c4833d5c530284e565a4 741 Gene3D G3DSA:3.40.50.620 280 364 7.2E-5 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS18120 7657b3ff3199c4833d5c530284e565a4 741 Gene3D G3DSA:3.40.50.620 591 710 8.1E-4 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS18120 7657b3ff3199c4833d5c530284e565a4 741 Gene3D G3DSA:3.40.50.620 223 244 7.2E-5 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS18120 7657b3ff3199c4833d5c530284e565a4 741 Gene3D G3DSA:3.60.20.10 107 202 3.0E-9 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS18120 7657b3ff3199c4833d5c530284e565a4 741 SUPERFAMILY SSF52402 562 628 1.6E-8 T 06-07-2017 SMD11_RS18120 7657b3ff3199c4833d5c530284e565a4 741 SUPERFAMILY SSF52402 270 421 1.6E-8 T 06-07-2017 SMD11_RS28940 a9fb827002a5fbcadaa8fdcd6267b584 190 SUPERFAMILY SSF55961 115 158 4.05E-6 T 06-07-2017 SMD11_RS28940 a9fb827002a5fbcadaa8fdcd6267b584 190 SUPERFAMILY SSF55961 23 89 4.05E-6 T 06-07-2017 SMD11_RS28940 a9fb827002a5fbcadaa8fdcd6267b584 190 Gene3D G3DSA:3.30.530.20 23 158 4.9E-4 T 06-07-2017 IPR023393 START-like domain SMD11_RS14060 1432fbf352f11e742e4c9ec117d2399a 538 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 315 335 7.8E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS14060 1432fbf352f11e742e4c9ec117d2399a 538 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 372 383 7.8E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS14060 1432fbf352f11e742e4c9ec117d2399a 538 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 439 455 7.8E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS14060 1432fbf352f11e742e4c9ec117d2399a 538 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 351 367 7.8E-18 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS14060 1432fbf352f11e742e4c9ec117d2399a 538 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 79 120 8.5E-15 T 06-07-2017 IPR011096 FTP domain SMD11_RS14060 1432fbf352f11e742e4c9ec117d2399a 538 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 217 360 6.6E-50 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS14060 1432fbf352f11e742e4c9ec117d2399a 538 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 363 537 5.6E-54 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 SMD11_RS14060 1432fbf352f11e742e4c9ec117d2399a 538 SUPERFAMILY SSF55486 216 537 6.04E-84 T 06-07-2017 SMD11_RS14060 1432fbf352f11e742e4c9ec117d2399a 538 Gene3D G3DSA:3.10.170.10 217 364 1.0E-46 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS14060 1432fbf352f11e742e4c9ec117d2399a 538 Gene3D G3DSA:1.10.390.10 365 537 3.0E-53 T 06-07-2017 SMD11_RS09325 2bedae495b859846425faf4711773156 837 Gene3D G3DSA:3.40.50.300 421 507 3.8E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09325 2bedae495b859846425faf4711773156 837 Gene3D G3DSA:3.40.50.300 629 820 3.8E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09325 2bedae495b859846425faf4711773156 837 SUPERFAMILY SSF52540 415 823 2.53E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01275 9b9d053df2e251a469706f6c5f1ae5fc 275 SUPERFAMILY SSF52540 10 235 5.11E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01275 9b9d053df2e251a469706f6c5f1ae5fc 275 SMART SM00382 34 223 5.8E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS01275 9b9d053df2e251a469706f6c5f1ae5fc 275 Pfam PF00005 ABC transporter 26 173 6.5E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS01275 9b9d053df2e251a469706f6c5f1ae5fc 275 Gene3D G3DSA:3.40.50.300 4 241 6.0E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01275 9b9d053df2e251a469706f6c5f1ae5fc 275 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS31445 14582ad32b96556642cf8108b7333ec5 611 SUPERFAMILY SSF50978 337 609 2.75E-38 T 06-07-2017 IPR017986 WD40-repeat-containing domain GO:0005515 SMD11_RS31445 14582ad32b96556642cf8108b7333ec5 611 SMART SM00320 432 480 60.0 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS31445 14582ad32b96556642cf8108b7333ec5 611 SMART SM00320 355 394 3.9E-4 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS31445 14582ad32b96556642cf8108b7333ec5 611 SMART SM00320 310 352 110.0 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS31445 14582ad32b96556642cf8108b7333ec5 611 SMART SM00320 524 562 0.47 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS31445 14582ad32b96556642cf8108b7333ec5 611 SMART SM00320 483 521 0.23 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS31445 14582ad32b96556642cf8108b7333ec5 611 SMART SM00320 567 606 0.19 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS31445 14582ad32b96556642cf8108b7333ec5 611 Pfam PF00400 WD domain, G-beta repeat 365 394 0.063 T 06-07-2017 IPR001680 WD40 repeat GO:0005515 SMD11_RS31445 14582ad32b96556642cf8108b7333ec5 611 Gene3D G3DSA:2.130.10.10 303 607 2.9E-40 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS03650 4969260c67bf384edf06495bda248374 350 PIRSF PIRSF015921 4 347 5.2E-76 T 06-07-2017 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 SMD11_RS03650 4969260c67bf384edf06495bda248374 350 Pfam PF00487 Fatty acid desaturase 61 321 1.5E-38 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 SMD11_RS17370 254d3bc598a18fcccb879e9027b8f477 460 SMART SM00327 256 430 2.2E-11 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS17370 254d3bc598a18fcccb879e9027b8f477 460 Pfam PF10138 vWA found in TerF C terminus 256 458 6.2E-68 T 06-07-2017 IPR019303 vWA found in TerF C terminus SMD11_RS17370 254d3bc598a18fcccb879e9027b8f477 460 SUPERFAMILY SSF53300 257 414 3.71E-16 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS17370 254d3bc598a18fcccb879e9027b8f477 460 Gene3D G3DSA:3.40.50.410 257 395 3.7E-6 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS23520 9d22fe37ec98fd91aec34d9ab3827031 565 Pfam PF00005 ABC transporter 359 498 2.4E-19 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS23520 9d22fe37ec98fd91aec34d9ab3827031 565 Gene3D G3DSA:1.20.1560.10 19 292 3.5E-18 T 06-07-2017 SMD11_RS23520 9d22fe37ec98fd91aec34d9ab3827031 565 SUPERFAMILY SSF52540 333 564 7.36E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23520 9d22fe37ec98fd91aec34d9ab3827031 565 SMART SM00382 367 544 1.7E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS23520 9d22fe37ec98fd91aec34d9ab3827031 565 Gene3D G3DSA:3.40.50.300 341 559 7.6E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23520 9d22fe37ec98fd91aec34d9ab3827031 565 SUPERFAMILY SSF90123 18 294 9.55E-25 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS18430 2340169cc3028685dc4e61c0d5b48d9c 234 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 14 225 30.348 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 SMD11_RS18430 2340169cc3028685dc4e61c0d5b48d9c 234 Pfam PF02441 Flavoprotein 16 166 6.1E-23 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD11_RS18430 2340169cc3028685dc4e61c0d5b48d9c 234 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 100 223 3.0E-35 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 SMD11_RS18430 2340169cc3028685dc4e61c0d5b48d9c 234 SUPERFAMILY SSF52507 100 225 1.7E-44 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD11_RS18430 2340169cc3028685dc4e61c0d5b48d9c 234 SUPERFAMILY SSF52507 15 71 1.7E-44 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD11_RS18430 2340169cc3028685dc4e61c0d5b48d9c 234 Gene3D G3DSA:3.40.50.1950 15 226 2.8E-64 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD11_RS20430 271e6c86136fcae1cb3a60fb24c71076 281 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 254 5.0E-69 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted SMD11_RS20430 271e6c86136fcae1cb3a60fb24c71076 281 Gene3D G3DSA:3.20.20.30 1 243 2.9E-58 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS20430 271e6c86136fcae1cb3a60fb24c71076 281 SUPERFAMILY SSF51679 17 250 1.83E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS20430 271e6c86136fcae1cb3a60fb24c71076 281 Pfam PF00296 Luciferase-like monooxygenase 18 242 3.2E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS07500 143a14c0805d962201df46c63ac7d33a 360 SUPERFAMILY SSF54001 204 318 2.52E-13 T 06-07-2017 SMD11_RS07500 143a14c0805d962201df46c63ac7d33a 360 Pfam PF00877 NlpC/P60 family 225 324 1.3E-8 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS07500 143a14c0805d962201df46c63ac7d33a 360 Gene3D G3DSA:3.90.1720.10 205 360 8.9E-18 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS20590 064db591bc1d23f68e6bd8466531f51f 398 Gene3D G3DSA:3.20.20.140 8 389 2.2E-148 T 06-07-2017 SMD11_RS20590 064db591bc1d23f68e6bd8466531f51f 398 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 14 373 4.4E-120 T 06-07-2017 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 SMD11_RS20590 064db591bc1d23f68e6bd8466531f51f 398 SUPERFAMILY SSF51556 7 256 8.32E-107 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS20590 064db591bc1d23f68e6bd8466531f51f 398 SUPERFAMILY SSF51556 296 384 8.32E-107 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS06620 41a5333c06a66cc5f65fb6c2e2a33570 335 Gene3D G3DSA:3.20.20.30 2 331 1.5E-69 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS06620 41a5333c06a66cc5f65fb6c2e2a33570 335 Pfam PF00296 Luciferase-like monooxygenase 10 306 1.5E-55 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS06620 41a5333c06a66cc5f65fb6c2e2a33570 335 TIGRFAM TIGR03842 F420_CPS_4043: F420-dependent oxidoreductase, CPS_4043 family 2 331 1.3E-178 T 06-07-2017 IPR022315 F420-dependent oxidoreductase-predicted, CPS4043 SMD11_RS06620 41a5333c06a66cc5f65fb6c2e2a33570 335 SUPERFAMILY SSF51679 2 329 2.09E-59 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS25280 d187c029ca29e438cba23399411f9ada 485 Gene3D G3DSA:2.130.10.10 320 465 2.4E-7 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS25280 d187c029ca29e438cba23399411f9ada 485 Gene3D G3DSA:2.130.10.10 203 260 2.4E-7 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS25280 d187c029ca29e438cba23399411f9ada 485 SUPERFAMILY SSF63829 335 471 5.23E-12 T 06-07-2017 SMD11_RS25280 d187c029ca29e438cba23399411f9ada 485 SUPERFAMILY SSF63829 204 275 5.23E-12 T 06-07-2017 SMD11_RS25280 d187c029ca29e438cba23399411f9ada 485 Pfam PF05787 Bacterial protein of unknown function (DUF839) 58 157 8.2E-16 T 06-07-2017 IPR008557 Protein of unknown function DUF839 SMD11_RS25280 d187c029ca29e438cba23399411f9ada 485 Pfam PF05787 Bacterial protein of unknown function (DUF839) 160 471 9.4E-63 T 06-07-2017 IPR008557 Protein of unknown function DUF839 SMD11_RS29735 096171b1a3f24ab9a26026d36782a5ea 685 SUPERFAMILY SSF55781 416 481 8.94E-8 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS29735 096171b1a3f24ab9a26026d36782a5ea 685 Gene3D G3DSA:3.30.565.10 555 675 2.5E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS29735 096171b1a3f24ab9a26026d36782a5ea 685 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 590 672 6.5E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS29735 096171b1a3f24ab9a26026d36782a5ea 685 SUPERFAMILY SSF55874 559 674 1.11E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS29735 096171b1a3f24ab9a26026d36782a5ea 685 Pfam PF07730 Histidine kinase 482 548 3.0E-11 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS29735 096171b1a3f24ab9a26026d36782a5ea 685 SMART SM00387 586 677 1.7E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS29735 096171b1a3f24ab9a26026d36782a5ea 685 Gene3D G3DSA:3.30.450.40 418 466 6.5E-6 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS04765 dbc78dd7b878b7596816b0b367a6180a 139 Gene3D G3DSA:1.10.10.60 62 116 4.6E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS04765 dbc78dd7b878b7596816b0b367a6180a 139 SUPERFAMILY SSF46689 59 110 9.86E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS04765 dbc78dd7b878b7596816b0b367a6180a 139 SUPERFAMILY SSF46689 8 57 1.48E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS04765 dbc78dd7b878b7596816b0b367a6180a 139 Pfam PF12833 Helix-turn-helix domain 29 108 1.5E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS04765 dbc78dd7b878b7596816b0b367a6180a 139 Gene3D G3DSA:1.10.10.60 8 61 6.1E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS04765 dbc78dd7b878b7596816b0b367a6180a 139 SMART SM00342 23 106 2.6E-32 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS23590 7a721eb10c0ff7ca0c7075440030cfb1 287 Gene3D G3DSA:3.10.129.10 1 145 1.4E-47 T 06-07-2017 IPR029069 HotDog domain SMD11_RS23590 7a721eb10c0ff7ca0c7075440030cfb1 287 Pfam PF13452 N-terminal half of MaoC dehydratase 16 132 3.3E-12 T 06-07-2017 SMD11_RS23590 7a721eb10c0ff7ca0c7075440030cfb1 287 Pfam PF01575 MaoC like domain 163 269 2.2E-28 T 06-07-2017 IPR002539 MaoC-like domain SMD11_RS23590 7a721eb10c0ff7ca0c7075440030cfb1 287 SUPERFAMILY SSF54637 12 158 7.46E-37 T 06-07-2017 IPR029069 HotDog domain SMD11_RS23590 7a721eb10c0ff7ca0c7075440030cfb1 287 Gene3D G3DSA:3.10.129.10 146 284 3.4E-42 T 06-07-2017 IPR029069 HotDog domain SMD11_RS23590 7a721eb10c0ff7ca0c7075440030cfb1 287 SUPERFAMILY SSF54637 161 280 6.15E-29 T 06-07-2017 IPR029069 HotDog domain SMD11_RS17110 f0c47f56320ed735d4ee5d9547a3741d 363 Gene3D G3DSA:2.40.30.10 8 105 4.0E-21 T 06-07-2017 SMD11_RS17110 f0c47f56320ed735d4ee5d9547a3741d 363 SUPERFAMILY SSF52343 103 250 4.85E-31 T 06-07-2017 SMD11_RS17110 f0c47f56320ed735d4ee5d9547a3741d 363 Gene3D G3DSA:3.40.50.80 106 245 7.9E-36 T 06-07-2017 SMD11_RS17110 f0c47f56320ed735d4ee5d9547a3741d 363 Pfam PF00175 Oxidoreductase NAD-binding domain 126 234 2.1E-10 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMD11_RS17110 f0c47f56320ed735d4ee5d9547a3741d 363 SUPERFAMILY SSF63380 8 118 1.16E-21 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD11_RS17110 f0c47f56320ed735d4ee5d9547a3741d 363 Gene3D G3DSA:3.10.20.30 246 359 2.7E-31 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS17110 f0c47f56320ed735d4ee5d9547a3741d 363 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 281 353 2.4E-15 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS17110 f0c47f56320ed735d4ee5d9547a3741d 363 SUPERFAMILY SSF54292 242 355 6.82E-28 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS17110 f0c47f56320ed735d4ee5d9547a3741d 363 PRINTS PR00406 Cytochrome B5 reductase signature 124 143 1.7E-5 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 SMD11_RS17110 f0c47f56320ed735d4ee5d9547a3741d 363 PRINTS PR00406 Cytochrome B5 reductase signature 102 116 1.7E-5 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 SMD11_RS17110 f0c47f56320ed735d4ee5d9547a3741d 363 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 310 318 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMD11_RS17110 f0c47f56320ed735d4ee5d9547a3741d 363 Pfam PF00970 Oxidoreductase FAD-binding domain 12 114 3.0E-10 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SMD11_RS00865 ea19a8f1639489a31b9cdebe1f24f324 248 Gene3D G3DSA:1.10.357.10 14 222 8.2E-19 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS00865 ea19a8f1639489a31b9cdebe1f24f324 248 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 2.7E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00865 ea19a8f1639489a31b9cdebe1f24f324 248 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 3.6E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00865 ea19a8f1639489a31b9cdebe1f24f324 248 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 3.6E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00865 ea19a8f1639489a31b9cdebe1f24f324 248 SUPERFAMILY SSF46689 11 89 4.77E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS03745 1fa24145636b08dea2e9ddeab7438cf9 261 SUPERFAMILY SSF161098 2 261 3.66E-65 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS03745 1fa24145636b08dea2e9ddeab7438cf9 261 Gene3D G3DSA:1.10.3720.10 2 248 3.6E-59 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS03745 1fa24145636b08dea2e9ddeab7438cf9 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 254 3.2E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS22445 bc7f3509871e605a9983349be9204fe3 106 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 06-07-2017 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS22445 bc7f3509871e605a9983349be9204fe3 106 SUPERFAMILY SSF141091 1 101 2.22E-29 T 06-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS22445 bc7f3509871e605a9983349be9204fe3 106 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 1.3E-25 T 06-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS22445 bc7f3509871e605a9983349be9204fe3 106 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 22.106 T 06-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS22445 bc7f3509871e605a9983349be9204fe3 106 Pfam PF00829 Ribosomal prokaryotic L21 protein 2 101 1.2E-30 T 06-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS31255 fe077b6b9475448c81f5e8555094c917 491 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 7 303 9.3E-53 T 06-07-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 SMD11_RS31255 fe077b6b9475448c81f5e8555094c917 491 Gene3D G3DSA:3.40.640.10 7 281 4.7E-83 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS31255 fe077b6b9475448c81f5e8555094c917 491 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 414 467 1.2E-12 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 SMD11_RS31255 fe077b6b9475448c81f5e8555094c917 491 Gene3D G3DSA:3.90.100.10 407 485 1.5E-23 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 SMD11_RS31255 fe077b6b9475448c81f5e8555094c917 491 Gene3D G3DSA:3.90.1150.10 330 392 2.4E-4 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS31255 fe077b6b9475448c81f5e8555094c917 491 SUPERFAMILY SSF53383 7 387 7.79E-74 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS02805 54ecf9f5cf8c2d00ae86050ab3e87ac0 120 SUPERFAMILY SSF46785 10 94 2.42E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02805 54ecf9f5cf8c2d00ae86050ab3e87ac0 120 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 3.2E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS02805 54ecf9f5cf8c2d00ae86050ab3e87ac0 120 Gene3D G3DSA:1.10.10.10 9 77 3.1E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02805 54ecf9f5cf8c2d00ae86050ab3e87ac0 120 SMART SM00345 17 76 9.9E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 Gene3D G3DSA:1.10.510.10 85 275 1.1E-48 T 06-07-2017 SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 SUPERFAMILY SSF54184 587 646 5.23E-5 T 06-07-2017 SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 Pfam PF00069 Protein kinase domain 19 268 1.9E-47 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 Gene3D G3DSA:3.30.200.20 11 84 1.4E-22 T 06-07-2017 SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 SMART SM00220 18 276 7.9E-55 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 SUPERFAMILY SSF56112 15 328 2.89E-73 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 SMART SM00740 448 515 1.7E-13 T 06-07-2017 IPR005543 PASTA domain SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 SMART SM00740 516 582 1.3E-15 T 06-07-2017 IPR005543 PASTA domain SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 SMART SM00740 583 647 1.7E-8 T 06-07-2017 IPR005543 PASTA domain SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 SMART SM00740 381 447 2.0E-13 T 06-07-2017 IPR005543 PASTA domain SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 SUPERFAMILY SSF54184 520 581 9.81E-6 T 06-07-2017 SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 Pfam PF03793 PASTA domain 521 582 9.9E-15 T 06-07-2017 IPR005543 PASTA domain SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 Pfam PF03793 PASTA domain 587 645 1.6E-11 T 06-07-2017 IPR005543 PASTA domain SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 Pfam PF03793 PASTA domain 453 515 1.0E-11 T 06-07-2017 IPR005543 PASTA domain SMD11_RS24385 855b93f6d0236f1c4df9ba2d565ad45f 649 Pfam PF03793 PASTA domain 387 446 1.4E-11 T 06-07-2017 IPR005543 PASTA domain SMD11_RS21740 b5f2cca80e97357a4feab2a32a272d78 543 SUPERFAMILY SSF52096 30 273 1.33E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS21740 b5f2cca80e97357a4feab2a32a272d78 543 Gene3D G3DSA:3.90.226.10 33 272 9.1E-79 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS21740 b5f2cca80e97357a4feab2a32a272d78 543 Gene3D G3DSA:3.90.226.10 282 529 7.5E-96 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS21740 b5f2cca80e97357a4feab2a32a272d78 543 SUPERFAMILY SSF52096 240 520 1.03E-89 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS21740 b5f2cca80e97357a4feab2a32a272d78 543 Pfam PF01039 Carboxyl transferase domain 51 527 2.4E-150 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS25550 80b15f62436e0f4ac729731872d375d6 474 SUPERFAMILY SSF52374 70 364 1.79E-77 T 06-07-2017 SMD11_RS25550 80b15f62436e0f4ac729731872d375d6 474 Gene3D G3DSA:3.10.290.10 360 416 2.5E-5 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 SMD11_RS25550 80b15f62436e0f4ac729731872d375d6 474 Pfam PF00579 tRNA synthetases class I (W and Y) 80 361 5.4E-57 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS25550 80b15f62436e0f4ac729731872d375d6 474 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 67 427 8.9E-87 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SMD11_RS25550 80b15f62436e0f4ac729731872d375d6 474 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 92 114 4.3E-21 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SMD11_RS25550 80b15f62436e0f4ac729731872d375d6 474 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 207 222 4.3E-21 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SMD11_RS25550 80b15f62436e0f4ac729731872d375d6 474 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 257 269 4.3E-21 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SMD11_RS25550 80b15f62436e0f4ac729731872d375d6 474 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 224 246 4.3E-21 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SMD11_RS25550 80b15f62436e0f4ac729731872d375d6 474 Gene3D G3DSA:3.40.50.620 68 274 6.1E-69 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS25550 80b15f62436e0f4ac729731872d375d6 474 Gene3D G3DSA:1.10.240.10 275 359 2.9E-24 T 06-07-2017 SMD11_RS25550 80b15f62436e0f4ac729731872d375d6 474 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 88 98 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS10440 1f6327dc2007b0378df56ece29b7da67 232 SMART SM00448 11 124 2.0E-19 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS10440 1f6327dc2007b0378df56ece29b7da67 232 Gene3D G3DSA:3.40.50.2300 8 130 1.7E-25 T 06-07-2017 SMD11_RS10440 1f6327dc2007b0378df56ece29b7da67 232 SUPERFAMILY SSF52172 9 146 1.34E-29 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS10440 1f6327dc2007b0378df56ece29b7da67 232 PIRSF PIRSF006171 9 231 5.7E-68 T 06-07-2017 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 SMD11_RS10440 1f6327dc2007b0378df56ece29b7da67 232 Pfam PF00072 Response regulator receiver domain 13 124 2.2E-19 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS02045 e8da8700f3e50bd9e14c38865a5b0cd6 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02045 e8da8700f3e50bd9e14c38865a5b0cd6 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02045 e8da8700f3e50bd9e14c38865a5b0cd6 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02045 e8da8700f3e50bd9e14c38865a5b0cd6 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 192 0.0016 T 06-07-2017 SMD11_RS02045 e8da8700f3e50bd9e14c38865a5b0cd6 255 SUPERFAMILY SSF51735 12 253 4.65E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS02045 e8da8700f3e50bd9e14c38865a5b0cd6 255 Gene3D G3DSA:3.40.50.720 10 253 1.6E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS02045 e8da8700f3e50bd9e14c38865a5b0cd6 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02045 e8da8700f3e50bd9e14c38865a5b0cd6 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02045 e8da8700f3e50bd9e14c38865a5b0cd6 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02045 e8da8700f3e50bd9e14c38865a5b0cd6 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02045 e8da8700f3e50bd9e14c38865a5b0cd6 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02045 e8da8700f3e50bd9e14c38865a5b0cd6 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02045 e8da8700f3e50bd9e14c38865a5b0cd6 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 251 3.5E-59 T 06-07-2017 SMD11_RS25100 4a73c74e0ac1a00afec9229cc7cd0367 300 Pfam PF03668 P-loop ATPase protein family 18 300 8.7E-112 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 SMD11_RS25100 4a73c74e0ac1a00afec9229cc7cd0367 300 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 17 299 41.222 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 SMD11_RS25100 4a73c74e0ac1a00afec9229cc7cd0367 300 SUPERFAMILY SSF52540 18 170 1.14E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25100 4a73c74e0ac1a00afec9229cc7cd0367 300 PIRSF PIRSF005052 17 300 7.3E-112 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 SMD11_RS25100 4a73c74e0ac1a00afec9229cc7cd0367 300 Gene3D G3DSA:3.40.50.300 17 171 9.2E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04770 e6cd290cacb7498151ff4e765fef342b 489 TIGRFAM TIGR00797 matE: MATE efflux family protein 25 443 1.6E-55 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SMD11_RS04770 e6cd290cacb7498151ff4e765fef342b 489 Pfam PF01554 MatE 106 198 4.4E-8 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SMD11_RS04770 e6cd290cacb7498151ff4e765fef342b 489 Pfam PF01554 MatE 264 430 1.2E-20 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SMD11_RS06295 a3bbf911fd02df0661a04754b7e53af8 120 Gene3D G3DSA:3.10.580.10 5 119 1.0E-33 T 06-07-2017 SMD11_RS06295 a3bbf911fd02df0661a04754b7e53af8 120 SMART SM00116 12 59 1.5E-7 T 06-07-2017 IPR000644 CBS domain SMD11_RS06295 a3bbf911fd02df0661a04754b7e53af8 120 SMART SM00116 77 119 9.6E-5 T 06-07-2017 IPR000644 CBS domain SMD11_RS06295 a3bbf911fd02df0661a04754b7e53af8 120 Pfam PF00571 CBS domain 72 119 1.5E-11 T 06-07-2017 IPR000644 CBS domain SMD11_RS06295 a3bbf911fd02df0661a04754b7e53af8 120 Pfam PF00571 CBS domain 5 55 1.3E-13 T 06-07-2017 IPR000644 CBS domain SMD11_RS06295 a3bbf911fd02df0661a04754b7e53af8 120 SUPERFAMILY SSF54631 4 119 7.33E-32 T 06-07-2017 SMD11_RS27755 dabba9f5f0b05fdf970768c1bde440ce 199 SUPERFAMILY SSF88659 119 177 7.2E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS27755 dabba9f5f0b05fdf970768c1bde440ce 199 Pfam PF04542 Sigma-70 region 2 25 90 2.2E-18 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS27755 dabba9f5f0b05fdf970768c1bde440ce 199 Pfam PF08281 Sigma-70, region 4 122 173 2.4E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS27755 dabba9f5f0b05fdf970768c1bde440ce 199 Gene3D G3DSA:1.10.10.10 122 178 2.0E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27755 dabba9f5f0b05fdf970768c1bde440ce 199 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 47 78 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS27755 dabba9f5f0b05fdf970768c1bde440ce 199 SUPERFAMILY SSF88946 3 103 1.88E-26 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS27755 dabba9f5f0b05fdf970768c1bde440ce 199 Gene3D G3DSA:1.10.1740.10 5 112 7.8E-27 T 06-07-2017 SMD11_RS27755 dabba9f5f0b05fdf970768c1bde440ce 199 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 176 1.3E-25 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS21155 50f48fcf84b56f6a2ad671b28f183cd6 380 SUPERFAMILY SSF54593 14 367 5.93E-91 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS21155 50f48fcf84b56f6a2ad671b28f183cd6 380 PIRSF PIRSF009283 9 380 8.7E-137 T 06-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 SMD11_RS21155 50f48fcf84b56f6a2ad671b28f183cd6 380 Gene3D G3DSA:3.10.180.10 15 185 3.7E-45 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS21155 50f48fcf84b56f6a2ad671b28f183cd6 380 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 22 380 2.3E-135 T 06-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 SMD11_RS21155 50f48fcf84b56f6a2ad671b28f183cd6 380 Gene3D G3DSA:3.10.180.10 186 380 2.2E-81 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS21155 50f48fcf84b56f6a2ad671b28f183cd6 380 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 184 334 3.8E-17 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS25305 49b63a610a15145bde03e50fa1b20997 366 Gene3D G3DSA:3.20.20.140 57 327 1.3E-61 T 06-07-2017 SMD11_RS25305 49b63a610a15145bde03e50fa1b20997 366 SUPERFAMILY SSF51556 55 329 3.1E-60 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS25305 49b63a610a15145bde03e50fa1b20997 366 Gene3D G3DSA:2.30.40.10 35 56 1.5E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS25305 49b63a610a15145bde03e50fa1b20997 366 Gene3D G3DSA:2.30.40.10 328 365 1.5E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS25305 49b63a610a15145bde03e50fa1b20997 366 Pfam PF01979 Amidohydrolase family 52 365 5.0E-13 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 SMD11_RS07250 11c1d12ce6418306c79767fac73ce3aa 394 SUPERFAMILY SSF53756 1 384 7.96E-79 T 06-07-2017 SMD11_RS07250 11c1d12ce6418306c79767fac73ce3aa 394 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 2 387 9.5E-131 T 06-07-2017 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 SMD11_RS07250 11c1d12ce6418306c79767fac73ce3aa 394 ProSitePatterns PS00375 UDP-glycosyltransferases signature. 278 319 - T 06-07-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 SMD11_RS07250 11c1d12ce6418306c79767fac73ce3aa 394 Gene3D G3DSA:3.40.50.2000 218 368 1.9E-33 T 06-07-2017 SMD11_RS07250 11c1d12ce6418306c79767fac73ce3aa 394 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 212 357 1.7E-16 T 06-07-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 SMD11_RS07250 11c1d12ce6418306c79767fac73ce3aa 394 Gene3D G3DSA:3.40.50.2000 2 122 1.9E-12 T 06-07-2017 SMD11_RS01435 8cf1a3f1af3b76abfea2c819c8bf0734 150 SMART SM00903 1 144 2.4E-44 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS01435 8cf1a3f1af3b76abfea2c819c8bf0734 150 Pfam PF01613 Flavin reductase like domain 1 143 2.2E-34 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS01435 8cf1a3f1af3b76abfea2c819c8bf0734 150 SUPERFAMILY SSF50475 2 145 4.32E-39 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS01435 8cf1a3f1af3b76abfea2c819c8bf0734 150 Gene3D G3DSA:2.30.110.10 1 144 3.4E-42 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS33595 b6c842570af8e8a3b669fdd6defe3411 489 PIRSF PIRSF002746 23 489 6.7E-157 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMD11_RS33595 b6c842570af8e8a3b669fdd6defe3411 489 Pfam PF02447 GntP family permease 28 486 1.0E-123 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMD11_RS33595 b6c842570af8e8a3b669fdd6defe3411 489 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 28 489 2.0E-112 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMD11_RS13525 a5db2bdadba111e343d614f017831ac4 373 SUPERFAMILY SSF55874 253 370 1.03E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS13525 a5db2bdadba111e343d614f017831ac4 373 Pfam PF07730 Histidine kinase 165 228 1.0E-14 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS18550 50847beace04d0f89474ea920f0c3ed6 440 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 75 86 - T 06-07-2017 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18550 50847beace04d0f89474ea920f0c3ed6 440 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 34 440 47.146 T 06-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18550 50847beace04d0f89474ea920f0c3ed6 440 SUPERFAMILY SSF56762 48 440 2.35E-124 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18550 50847beace04d0f89474ea920f0c3ed6 440 Gene3D G3DSA:1.10.645.10 31 324 2.7E-68 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18550 50847beace04d0f89474ea920f0c3ed6 440 Gene3D G3DSA:1.10.645.10 368 433 2.7E-68 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18550 50847beace04d0f89474ea920f0c3ed6 440 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 38 440 3.2E-175 T 06-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18550 50847beace04d0f89474ea920f0c3ed6 440 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 155 440 1.4E-114 T 06-07-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS32130 79cd9521cef38ae0e5b8f4e71c463f48 669 SMART SM00382 418 616 3.2E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS32130 79cd9521cef38ae0e5b8f4e71c463f48 669 SUPERFAMILY SSF52540 390 632 8.71E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS32130 79cd9521cef38ae0e5b8f4e71c463f48 669 Gene3D G3DSA:1.20.1560.10 64 357 3.5E-10 T 06-07-2017 SMD11_RS32130 79cd9521cef38ae0e5b8f4e71c463f48 669 Pfam PF00005 ABC transporter 409 563 1.1E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS32130 79cd9521cef38ae0e5b8f4e71c463f48 669 Gene3D G3DSA:3.40.50.300 391 628 5.1E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS32130 79cd9521cef38ae0e5b8f4e71c463f48 669 SUPERFAMILY SSF90123 63 356 3.53E-14 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS15350 15c8a4750ce057cddad0ee896e6ccb19 273 Gene3D G3DSA:1.10.3290.10 106 250 8.6E-6 T 06-07-2017 IPR003812 Fido domain SMD11_RS20975 4eaef6c2ba93af5465c57552d30416e2 319 SUPERFAMILY SSF46785 7 88 3.41E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20975 4eaef6c2ba93af5465c57552d30416e2 319 SUPERFAMILY SSF53850 97 298 1.99E-11 T 06-07-2017 SMD11_RS20975 4eaef6c2ba93af5465c57552d30416e2 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.1E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS20975 4eaef6c2ba93af5465c57552d30416e2 319 Gene3D G3DSA:1.10.10.10 5 84 3.1E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20975 4eaef6c2ba93af5465c57552d30416e2 319 Gene3D G3DSA:3.40.190.10 178 268 2.1E-6 T 06-07-2017 SMD11_RS20975 4eaef6c2ba93af5465c57552d30416e2 319 Pfam PF03466 LysR substrate binding domain 104 293 6.3E-11 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS20975 4eaef6c2ba93af5465c57552d30416e2 319 Gene3D G3DSA:3.40.190.10 95 177 1.2E-8 T 06-07-2017 SMD11_RS20975 4eaef6c2ba93af5465c57552d30416e2 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.4E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS20975 4eaef6c2ba93af5465c57552d30416e2 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.4E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS20975 4eaef6c2ba93af5465c57552d30416e2 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.4E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS16785 9d2fa798b47953cd565ad980ea9c1558 372 SUPERFAMILY SSF55729 5 114 2.07E-36 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS16785 9d2fa798b47953cd565ad980ea9c1558 372 SUPERFAMILY SSF55729 143 194 2.07E-36 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS16785 9d2fa798b47953cd565ad980ea9c1558 372 Gene3D G3DSA:3.40.630.30 148 184 1.7E-55 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS16785 9d2fa798b47953cd565ad980ea9c1558 372 Gene3D G3DSA:3.40.630.30 1 116 1.7E-55 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS16785 9d2fa798b47953cd565ad980ea9c1558 372 SUPERFAMILY SSF55729 183 365 9.91E-39 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS16785 9d2fa798b47953cd565ad980ea9c1558 372 Pfam PF02388 FemAB family 268 366 8.2E-17 T 06-07-2017 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 SMD11_RS16785 9d2fa798b47953cd565ad980ea9c1558 372 Pfam PF02388 FemAB family 8 248 2.3E-31 T 06-07-2017 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 SMD11_RS16785 9d2fa798b47953cd565ad980ea9c1558 372 Gene3D G3DSA:3.40.630.30 185 345 1.6E-52 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS14535 96286e92efee5c78a75af7675c509bda 443 SUPERFAMILY SSF52172 53 168 1.3E-14 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS14535 96286e92efee5c78a75af7675c509bda 443 SMART SM00331 184 408 3.6E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS14535 96286e92efee5c78a75af7675c509bda 443 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 213 408 1.0E-34 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS14535 96286e92efee5c78a75af7675c509bda 443 Pfam PF00072 Response regulator receiver domain 54 131 8.1E-8 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS14535 96286e92efee5c78a75af7675c509bda 443 Gene3D G3DSA:3.40.50.2300 51 151 2.7E-16 T 06-07-2017 SMD11_RS02820 0ff0b473fe453766de6eb3532843b4ac 331 ProDom PD031536 MEMBRANE TRANSMEMBRANE YVAX YITN 190 297 3.0E-6 T 06-07-2017 SMD11_RS02820 0ff0b473fe453766de6eb3532843b4ac 331 SMART SM00752 11 287 3.1E-15 T 06-07-2017 IPR011020 HTTM Reactome: R-HSA-159740 SMD11_RS02820 0ff0b473fe453766de6eb3532843b4ac 331 ProDom PD027642 TRANSMEMBRANE MEMBRANE YVAX YITO 69 136 8.0E-9 T 06-07-2017 SMD11_RS02820 0ff0b473fe453766de6eb3532843b4ac 331 Pfam PF05090 Vitamin K-dependent gamma-carboxylase 165 286 2.3E-6 T 06-07-2017 IPR007782 Vitamin K-dependent gamma-carboxylase GO:0008488|GO:0017187 KEGG: 00130+4.1.1.90|Reactome: R-HSA-159740 SMD11_RS02820 0ff0b473fe453766de6eb3532843b4ac 331 TIGRFAM TIGR04033 export_SdpB: antimicrobial peptide system protein, SdpB family 11 286 7.7E-84 T 06-07-2017 IPR023894 Sporulation delaying protein SdpB SMD11_RS04685 5e2470e8c95e6c8ad8f8b039bcd6fc29 272 Pfam PF09359 VTC domain 53 142 9.2E-6 T 06-07-2017 IPR018966 VTC domain SMD11_RS04685 5e2470e8c95e6c8ad8f8b039bcd6fc29 272 SUPERFAMILY SSF55154 79 252 6.87E-7 T 06-07-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 SMD11_RS16710 8fdf225ecacf6f0666692c8a9ffe9d5f 125 Gene3D G3DSA:3.40.30.10 7 116 8.2E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS16710 8fdf225ecacf6f0666692c8a9ffe9d5f 125 TIGRFAM TIGR01068 thioredoxin: thioredoxin 20 117 2.2E-30 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMD11_RS16710 8fdf225ecacf6f0666692c8a9ffe9d5f 125 PRINTS PR00421 Thioredoxin family signature 83 94 1.5E-7 T 06-07-2017 SMD11_RS16710 8fdf225ecacf6f0666692c8a9ffe9d5f 125 PRINTS PR00421 Thioredoxin family signature 43 52 1.5E-7 T 06-07-2017 SMD11_RS16710 8fdf225ecacf6f0666692c8a9ffe9d5f 125 PRINTS PR00421 Thioredoxin family signature 35 43 1.5E-7 T 06-07-2017 SMD11_RS16710 8fdf225ecacf6f0666692c8a9ffe9d5f 125 SUPERFAMILY SSF52833 14 117 2.4E-34 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS16710 8fdf225ecacf6f0666692c8a9ffe9d5f 125 PIRSF PIRSF000077 13 119 4.9E-35 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SMD11_RS16710 8fdf225ecacf6f0666692c8a9ffe9d5f 125 ProSitePatterns PS00194 Thioredoxin family active site. 36 54 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 SMD11_RS16710 8fdf225ecacf6f0666692c8a9ffe9d5f 125 Pfam PF00085 Thioredoxin 16 116 5.5E-27 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 SMD11_RS11635 7f47a9d14e50bf075fe0c32d6a93f5f7 510 Pfam PF08386 TAP-like protein 405 509 1.8E-33 T 06-07-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMD11_RS11635 7f47a9d14e50bf075fe0c32d6a93f5f7 510 SUPERFAMILY SSF53474 93 154 2.46E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS11635 7f47a9d14e50bf075fe0c32d6a93f5f7 510 SUPERFAMILY SSF53474 197 260 2.46E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS11635 7f47a9d14e50bf075fe0c32d6a93f5f7 510 SUPERFAMILY SSF53474 287 479 2.46E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS11635 7f47a9d14e50bf075fe0c32d6a93f5f7 510 Gene3D G3DSA:3.40.50.1820 376 497 1.7E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS11635 7f47a9d14e50bf075fe0c32d6a93f5f7 510 Gene3D G3DSA:3.40.50.1820 200 326 1.7E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS11635 7f47a9d14e50bf075fe0c32d6a93f5f7 510 Gene3D G3DSA:3.40.50.1820 72 156 1.7E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12970 354978a11f14b518a8e3229b8933b27a 121 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 121 64.238 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 SMD11_RS12970 354978a11f14b518a8e3229b8933b27a 121 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 119 8.5E-44 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 SMD11_RS12970 354978a11f14b518a8e3229b8933b27a 121 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 95 3.0E-23 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 SMD11_RS12970 354978a11f14b518a8e3229b8933b27a 121 Gene3D G3DSA:2.40.40.20 1 119 5.6E-50 T 06-07-2017 SMD11_RS12970 354978a11f14b518a8e3229b8933b27a 121 SUPERFAMILY SSF50692 1 116 1.62E-44 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain SMD11_RS12970 354978a11f14b518a8e3229b8933b27a 121 PIRSF PIRSF006246 1 121 6.0E-50 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 SMD11_RS12970 354978a11f14b518a8e3229b8933b27a 121 Pfam PF02261 Aspartate decarboxylase 1 114 1.6E-47 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 SMD11_RS27800 c122e997a0b4b799921e158bff12f7c1 246 Pfam PF02585 GlcNAc-PI de-N-acetylase 16 147 1.5E-23 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SMD11_RS27800 c122e997a0b4b799921e158bff12f7c1 246 Gene3D G3DSA:3.40.50.10320 11 243 1.3E-45 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD11_RS27800 c122e997a0b4b799921e158bff12f7c1 246 SUPERFAMILY SSF102588 12 210 2.88E-40 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 SUPERFAMILY SSF47781 432 525 4.82E-44 T 06-07-2017 IPR010994 RuvA domain 2-like SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 SUPERFAMILY SSF47781 556 649 4.82E-44 T 06-07-2017 IPR010994 RuvA domain 2-like SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 SMART SM00292 658 735 8.4E-10 T 06-07-2017 IPR001357 BRCT domain SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 351 427 6.5E-28 T 06-07-2017 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 Gene3D G3DSA:3.40.50.10190 657 735 3.2E-23 T 06-07-2017 IPR001357 BRCT domain SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 SUPERFAMILY SSF52113 657 732 1.12E-17 T 06-07-2017 IPR001357 BRCT domain SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 39 521 1.9E-174 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 Gene3D G3DSA:1.10.150.20 569 650 9.3E-28 T 06-07-2017 SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 SMART SM00532 31 478 5.9E-258 T 06-07-2017 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 Hamap MF_01588 DNA ligase [ligA]. 30 732 51.163 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 Gene3D G3DSA:1.10.287.610 29 93 5.2E-28 T 06-07-2017 SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 360 375 - T 06-07-2017 IPR033136 NAD-dependent DNA ligase, conserved site SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 PIRSF PIRSF001604 26 736 2.2E-237 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 Gene3D G3DSA:3.30.470.30 147 279 7.4E-52 T 06-07-2017 SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 31 347 2.2E-123 T 06-07-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 658 728 3.3E-12 T 06-07-2017 IPR001357 BRCT domain SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 SUPERFAMILY SSF56091 30 344 4.32E-112 T 06-07-2017 SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 143 172 - T 06-07-2017 IPR018239 NAD-dependent DNA ligase, active site SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 SUPERFAMILY SSF50249 347 429 5.65E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 Gene3D G3DSA:2.40.50.140 349 419 4.9E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 Pfam PF12826 Helix-hairpin-helix motif 575 638 4.0E-21 T 06-07-2017 SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 Gene3D G3DSA:1.10.150.20 465 521 4.1E-8 T 06-07-2017 SMD11_RS10145 14d9783c9a656d8894bd82a0f67aba44 747 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 436 464 7.1E-7 T 06-07-2017 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 SMD11_RS18775 eea90d8e9e7810fbabb9941298c011c9 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 19.67 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18775 eea90d8e9e7810fbabb9941298c011c9 54 SUPERFAMILY SSF57829 4 54 9.77E-20 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 SMD11_RS18775 eea90d8e9e7810fbabb9941298c011c9 54 Pfam PF00471 Ribosomal protein L33 9 54 4.1E-23 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18775 eea90d8e9e7810fbabb9941298c011c9 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 06-07-2017 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18775 eea90d8e9e7810fbabb9941298c011c9 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 54 1.1E-21 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS08790 3299594cb1c0554b74bf0bf7d1f18ac9 207 SUPERFAMILY SSF48498 77 182 9.34E-13 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS08790 3299594cb1c0554b74bf0bf7d1f18ac9 207 Gene3D G3DSA:1.10.357.10 9 169 1.2E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS08790 3299594cb1c0554b74bf0bf7d1f18ac9 207 SUPERFAMILY SSF46689 7 79 2.77E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS08790 3299594cb1c0554b74bf0bf7d1f18ac9 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 5.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS08790 3299594cb1c0554b74bf0bf7d1f18ac9 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 5.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS08790 3299594cb1c0554b74bf0bf7d1f18ac9 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 55 5.6E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS26150 c7d0d255babac1135d56a7c2e1644ea9 275 Gene3D G3DSA:3.40.50.1110 41 264 1.6E-63 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS26150 c7d0d255babac1135d56a7c2e1644ea9 275 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 47 263 7.5E-23 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS26150 c7d0d255babac1135d56a7c2e1644ea9 275 SUPERFAMILY SSF52266 43 263 6.0E-59 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS12850 831d271076a995804a6992417e0851e7 308 Gene3D G3DSA:3.20.20.70 11 277 1.4E-98 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS12850 831d271076a995804a6992417e0851e7 308 SUPERFAMILY SSF51569 11 289 1.95E-83 T 06-07-2017 SMD11_RS12850 831d271076a995804a6992417e0851e7 308 Pfam PF03102 NeuB family 41 277 4.3E-80 T 06-07-2017 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 SMD11_RS17535 1077f2ca8128368d402273d97c047a23 82 Pfam PF14026 Protein of unknown function (DUF4242) 4 78 7.0E-25 T 06-07-2017 IPR025336 Protein of unknown function DUF4242 SMD11_RS13580 1b1d573cf149db289f12e15c39a42a12 230 Gene3D G3DSA:1.10.10.10 2 73 6.5E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13580 1b1d573cf149db289f12e15c39a42a12 230 SUPERFAMILY SSF47979 65 137 6.28E-26 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SMD11_RS13580 1b1d573cf149db289f12e15c39a42a12 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 62 1.7E-19 T 06-07-2017 IPR022687 DTXR-type HTH domain GO:0003677 SMD11_RS13580 1b1d573cf149db289f12e15c39a42a12 230 Gene3D G3DSA:1.10.60.10 75 133 9.2E-30 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SMD11_RS13580 1b1d573cf149db289f12e15c39a42a12 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 3.5E-29 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SMD11_RS13580 1b1d573cf149db289f12e15c39a42a12 230 Pfam PF04023 FeoA domain 162 228 1.9E-7 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SMD11_RS13580 1b1d573cf149db289f12e15c39a42a12 230 SMART SM00529 26 125 7.7E-48 T 06-07-2017 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 SMD11_RS13580 1b1d573cf149db289f12e15c39a42a12 230 SUPERFAMILY SSF50037 130 229 1.6E-23 T 06-07-2017 IPR008988 Transcriptional repressor, C-terminal SMD11_RS13580 1b1d573cf149db289f12e15c39a42a12 230 SMART SM00899 153 229 7.4E-8 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SMD11_RS13580 1b1d573cf149db289f12e15c39a42a12 230 SUPERFAMILY SSF46785 3 62 1.13E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13580 1b1d573cf149db289f12e15c39a42a12 230 Gene3D G3DSA:2.30.30.90 134 229 3.0E-31 T 06-07-2017 SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 Pfam PF17203 Single cache domain 3 79 209 2.6E-25 T 06-07-2017 IPR033463 Single cache domain 3 SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 599 792 4.9E-55 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 Gene3D G3DSA:3.30.450.20 256 352 5.7E-8 T 06-07-2017 SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 SMART SM00065 368 554 4.0E-4 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 SUPERFAMILY SSF81606 586 791 3.66E-10 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 SUPERFAMILY SSF103190 82 211 2.16E-29 T 06-07-2017 IPR029151 Periplasmic sensor domain-like SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 SMART SM00331 572 792 1.3E-40 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 Pfam PF13581 Histidine kinase-like ATPase domain 806 913 1.9E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 Gene3D G3DSA:3.30.450.40 373 552 5.6E-38 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 Gene3D G3DSA:3.30.450.20 76 213 5.3E-38 T 06-07-2017 SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 SUPERFAMILY SSF55785 250 352 9.33E-7 T 06-07-2017 IPR000014 PAS domain SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 Pfam PF08448 PAS fold 262 357 3.8E-6 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 Pfam PF01590 GAF domain 461 544 4.7E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 SUPERFAMILY SSF55874 836 914 6.97E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 SUPERFAMILY SSF55781 457 555 1.79E-14 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS32110 2da62a085f3f6ed5bbbf4636761a89a2 919 SMART SM00091 255 320 0.0028 T 06-07-2017 IPR000014 PAS domain SMD11_RS15365 db258aa9a3766c702847da9bc6038ff5 770 SMART SM00947 572 753 1.9E-49 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS15365 db258aa9a3766c702847da9bc6038ff5 770 Pfam PF00484 Carbonic anhydrase 580 747 4.3E-41 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS15365 db258aa9a3766c702847da9bc6038ff5 770 Gene3D G3DSA:3.30.750.24 433 511 6.0E-5 T 06-07-2017 IPR002645 STAS domain SMD11_RS15365 db258aa9a3766c702847da9bc6038ff5 770 Gene3D G3DSA:3.40.1050.10 537 764 1.4E-76 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS15365 db258aa9a3766c702847da9bc6038ff5 770 Pfam PF00916 Sulfate permease family 38 393 6.5E-58 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 SMD11_RS15365 db258aa9a3766c702847da9bc6038ff5 770 SUPERFAMILY SSF52091 432 511 5.89E-5 T 06-07-2017 IPR002645 STAS domain SMD11_RS15365 db258aa9a3766c702847da9bc6038ff5 770 SUPERFAMILY SSF53056 545 759 2.49E-47 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS33320 23b579edb6fd6dcf0865d89eaf23e338 468 Gene3D G3DSA:3.40.50.150 6 246 1.2E-53 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS33320 23b579edb6fd6dcf0865d89eaf23e338 468 Gene3D G3DSA:3.40.50.150 283 435 1.8E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS33320 23b579edb6fd6dcf0865d89eaf23e338 468 Pfam PF08241 Methyltransferase domain 73 168 5.9E-25 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS33320 23b579edb6fd6dcf0865d89eaf23e338 468 Pfam PF08241 Methyltransferase domain 324 417 1.1E-14 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS33320 23b579edb6fd6dcf0865d89eaf23e338 468 SUPERFAMILY SSF53335 10 244 5.03E-54 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS33320 23b579edb6fd6dcf0865d89eaf23e338 468 SUPERFAMILY SSF53335 283 453 1.82E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS25465 af787f293843dad442f02964d52046f9 111 Pfam PF03780 Asp23 family, cell envelope-related function 6 95 6.7E-7 T 06-07-2017 IPR005531 Alkaline shock protein Asp23 SMD11_RS31370 1024f1b73cac7e0aa80ba98a9981f97e 363 Gene3D G3DSA:1.10.12.10 266 325 1.1E-5 T 06-07-2017 IPR014748 Crontonase, C-terminal SMD11_RS31370 1024f1b73cac7e0aa80ba98a9981f97e 363 Pfam PF16113 Enoyl-CoA hydratase/isomerase 22 342 4.0E-126 T 06-07-2017 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 SMD11_RS31370 1024f1b73cac7e0aa80ba98a9981f97e 363 Gene3D G3DSA:3.90.226.10 11 206 8.3E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS31370 1024f1b73cac7e0aa80ba98a9981f97e 363 SUPERFAMILY SSF52096 256 327 3.48E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS31370 1024f1b73cac7e0aa80ba98a9981f97e 363 SUPERFAMILY SSF52096 7 200 3.48E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS08030 fe6c7b7e89bf6750ad5ba6b47273d78a 237 Gene3D G3DSA:2.20.130.10 152 199 3.9E-28 T 06-07-2017 SMD11_RS08030 fe6c7b7e89bf6750ad5ba6b47273d78a 237 Pfam PF13649 Methyltransferase domain 43 133 3.9E-15 T 06-07-2017 SMD11_RS08030 fe6c7b7e89bf6750ad5ba6b47273d78a 237 Gene3D G3DSA:3.40.50.150 200 220 6.0E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS08030 fe6c7b7e89bf6750ad5ba6b47273d78a 237 Gene3D G3DSA:3.40.50.150 4 151 6.0E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS08030 fe6c7b7e89bf6750ad5ba6b47273d78a 237 SUPERFAMILY SSF53335 4 225 6.48E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS28305 242b8cebce1f395cd7e3a516db1a11ed 301 Gene3D G3DSA:3.40.50.720 1 126 3.4E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS28305 242b8cebce1f395cd7e3a516db1a11ed 301 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 121 9.3E-14 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD11_RS28305 242b8cebce1f395cd7e3a516db1a11ed 301 Gene3D G3DSA:3.30.360.10 127 298 2.5E-56 T 06-07-2017 SMD11_RS28305 242b8cebce1f395cd7e3a516db1a11ed 301 SUPERFAMILY SSF55347 123 258 5.45E-35 T 06-07-2017 SMD11_RS28305 242b8cebce1f395cd7e3a516db1a11ed 301 SUPERFAMILY SSF51735 1 137 6.68E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS31025 48d112dac0c6842056eac3be475862a7 327 Gene3D G3DSA:1.10.10.10 259 309 1.7E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS31025 48d112dac0c6842056eac3be475862a7 327 Pfam PF12840 Helix-turn-helix domain 254 302 1.2E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS31025 48d112dac0c6842056eac3be475862a7 327 SUPERFAMILY SSF46785 259 315 1.89E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07855 ffc08618763b4bc7b61659453a9bc9b1 357 Gene3D G3DSA:3.40.50.150 26 159 7.1E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS07855 ffc08618763b4bc7b61659453a9bc9b1 357 Pfam PF07021 Methionine biosynthesis protein MetW 46 97 6.3E-5 T 06-07-2017 IPR010743 Methionine biosynthesis MetW SMD11_RS07855 ffc08618763b4bc7b61659453a9bc9b1 357 Gene3D G3DSA:2.70.160.11 212 314 3.4E-6 T 06-07-2017 SMD11_RS07855 ffc08618763b4bc7b61659453a9bc9b1 357 Pfam PF05185 PRMT5 arginine-N-methyltransferase 116 314 8.3E-18 T 06-07-2017 IPR025799 Protein arginine N-methyltransferase GO:0006479|GO:0008168 SMD11_RS07855 ffc08618763b4bc7b61659453a9bc9b1 357 SUPERFAMILY SSF53335 29 316 2.81E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS00560 062700e767240a7ddf070b8ca5f97939 541 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 180 2.9E-44 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMD11_RS00560 062700e767240a7ddf070b8ca5f97939 541 Gene3D G3DSA:3.40.50.970 364 528 6.1E-42 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS00560 062700e767240a7ddf070b8ca5f97939 541 Gene3D G3DSA:3.40.50.1220 194 339 5.9E-38 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS00560 062700e767240a7ddf070b8ca5f97939 541 SUPERFAMILY SSF52467 163 356 1.04E-33 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS00560 062700e767240a7ddf070b8ca5f97939 541 SUPERFAMILY SSF52518 8 184 5.44E-41 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS00560 062700e767240a7ddf070b8ca5f97939 541 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 421 440 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 SMD11_RS00560 062700e767240a7ddf070b8ca5f97939 541 SUPERFAMILY SSF52518 366 530 1.55E-40 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS00560 062700e767240a7ddf070b8ca5f97939 541 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 330 1.1E-27 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMD11_RS00560 062700e767240a7ddf070b8ca5f97939 541 Gene3D G3DSA:3.40.50.970 8 184 8.5E-49 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS00560 062700e767240a7ddf070b8ca5f97939 541 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 528 4.3E-30 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMD11_RS30165 95a9794ac1a66ed74efe313e631576a8 850 SUPERFAMILY SSF52777 609 839 2.11E-28 T 06-07-2017 SMD11_RS30165 95a9794ac1a66ed74efe313e631576a8 850 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 3.8E-17 T 06-07-2017 SMD11_RS30165 95a9794ac1a66ed74efe313e631576a8 850 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 3.8E-17 T 06-07-2017 SMD11_RS30165 95a9794ac1a66ed74efe313e631576a8 850 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 3.8E-17 T 06-07-2017 SMD11_RS30165 95a9794ac1a66ed74efe313e631576a8 850 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 337 353 3.8E-17 T 06-07-2017 SMD11_RS30165 95a9794ac1a66ed74efe313e631576a8 850 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 3.8E-17 T 06-07-2017 SMD11_RS30165 95a9794ac1a66ed74efe313e631576a8 850 SUPERFAMILY SSF51905 11 176 4.17E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS30165 95a9794ac1a66ed74efe313e631576a8 850 SUPERFAMILY SSF51905 273 379 4.17E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS30165 95a9794ac1a66ed74efe313e631576a8 850 Pfam PF01494 FAD binding domain 11 351 1.3E-25 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS30165 95a9794ac1a66ed74efe313e631576a8 850 SUPERFAMILY SSF52777 404 569 5.67E-18 T 06-07-2017 SMD11_RS30165 95a9794ac1a66ed74efe313e631576a8 850 Pfam PF00668 Condensation domain 436 549 3.9E-7 T 06-07-2017 IPR001242 Condensation domain SMD11_RS30165 95a9794ac1a66ed74efe313e631576a8 850 Gene3D G3DSA:3.50.50.60 11 183 5.2E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS30165 95a9794ac1a66ed74efe313e631576a8 850 Gene3D G3DSA:3.50.50.60 273 357 5.2E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS16660 2a84b9b4c09c5335e6dc49bc859a592c 601 Pfam PF00970 Oxidoreductase FAD-binding domain 374 465 2.1E-10 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 SMD11_RS16660 2a84b9b4c09c5335e6dc49bc859a592c 601 Pfam PF00175 Oxidoreductase NAD-binding domain 478 575 3.5E-10 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 SMD11_RS16660 2a84b9b4c09c5335e6dc49bc859a592c 601 Gene3D G3DSA:2.40.30.10 367 464 3.9E-23 T 06-07-2017 SMD11_RS16660 2a84b9b4c09c5335e6dc49bc859a592c 601 SUPERFAMILY SSF52343 471 593 1.31E-26 T 06-07-2017 SMD11_RS16660 2a84b9b4c09c5335e6dc49bc859a592c 601 Gene3D G3DSA:3.40.50.80 471 594 7.7E-28 T 06-07-2017 SMD11_RS16660 2a84b9b4c09c5335e6dc49bc859a592c 601 SUPERFAMILY SSF46458 234 359 1.41E-29 T 06-07-2017 IPR009050 Globin-like SMD11_RS16660 2a84b9b4c09c5335e6dc49bc859a592c 601 Pfam PF00042 Globin 235 325 8.9E-9 T 06-07-2017 IPR000971 Globin GO:0019825|GO:0020037 SMD11_RS16660 2a84b9b4c09c5335e6dc49bc859a592c 601 PRINTS PR00410 Phenol hydroxylase reductase family signature 476 495 4.6E-15 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD11_RS16660 2a84b9b4c09c5335e6dc49bc859a592c 601 PRINTS PR00410 Phenol hydroxylase reductase family signature 563 571 4.6E-15 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD11_RS16660 2a84b9b4c09c5335e6dc49bc859a592c 601 PRINTS PR00410 Phenol hydroxylase reductase family signature 501 510 4.6E-15 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD11_RS16660 2a84b9b4c09c5335e6dc49bc859a592c 601 PRINTS PR00410 Phenol hydroxylase reductase family signature 398 410 4.6E-15 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 SMD11_RS16660 2a84b9b4c09c5335e6dc49bc859a592c 601 Gene3D G3DSA:1.10.490.10 236 363 1.4E-37 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 SMD11_RS16660 2a84b9b4c09c5335e6dc49bc859a592c 601 SUPERFAMILY SSF63380 370 465 2.33E-22 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SMD11_RS18060 6f1055f2d0f5f5f4778a2854eef30baf 155 Gene3D G3DSA:3.30.530.20 4 151 1.6E-30 T 06-07-2017 IPR023393 START-like domain SMD11_RS18060 6f1055f2d0f5f5f4778a2854eef30baf 155 SUPERFAMILY SSF55961 7 146 9.42E-24 T 06-07-2017 SMD11_RS18060 6f1055f2d0f5f5f4778a2854eef30baf 155 Pfam PF08982 Domain of unknown function (DUF1857) 4 149 9.1E-25 T 06-07-2017 IPR015075 Protein of unknown function DUF1857 SMD11_RS12030 87ef8ea746af8814617733ef850572c0 542 Gene3D G3DSA:3.10.105.10 324 511 2.5E-36 T 06-07-2017 SMD11_RS12030 87ef8ea746af8814617733ef850572c0 542 Gene3D G3DSA:3.90.76.10 55 209 2.5E-28 T 06-07-2017 SMD11_RS12030 87ef8ea746af8814617733ef850572c0 542 PIRSF PIRSF002741 3 540 9.5E-61 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD11_RS12030 87ef8ea746af8814617733ef850572c0 542 Gene3D G3DSA:3.40.190.10 210 323 4.6E-22 T 06-07-2017 SMD11_RS12030 87ef8ea746af8814617733ef850572c0 542 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 459 2.9E-50 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain SMD11_RS12030 87ef8ea746af8814617733ef850572c0 542 SUPERFAMILY SSF53850 39 539 1.1E-83 T 06-07-2017 SMD11_RS30380 55b064cfc86fded948e6f55bdd92552e 112 Gene3D G3DSA:3.40.30.10 9 111 1.0E-15 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS30380 55b064cfc86fded948e6f55bdd92552e 112 SUPERFAMILY SSF52833 7 111 2.25E-18 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS30380 55b064cfc86fded948e6f55bdd92552e 112 Pfam PF00085 Thioredoxin 20 111 9.0E-11 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 SMD11_RS27230 bddc5f3314f67ac44ac4b3836ce48c96 240 SMART SM00849 12 202 5.3E-37 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS27230 bddc5f3314f67ac44ac4b3836ce48c96 240 Gene3D G3DSA:3.60.15.10 9 220 1.1E-51 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS27230 bddc5f3314f67ac44ac4b3836ce48c96 240 Pfam PF00753 Metallo-beta-lactamase superfamily 9 202 2.0E-28 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS27230 bddc5f3314f67ac44ac4b3836ce48c96 240 SUPERFAMILY SSF56281 6 219 1.06E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS14765 2a972169f79252622d72b85da66fae9f 182 SUPERFAMILY SSF88659 89 165 4.11E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS14765 2a972169f79252622d72b85da66fae9f 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 160 4.9E-26 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS14765 2a972169f79252622d72b85da66fae9f 182 SUPERFAMILY SSF88946 4 76 2.0E-12 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS14765 2a972169f79252622d72b85da66fae9f 182 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 6 163 1.8E-61 T 06-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMD11_RS14765 2a972169f79252622d72b85da66fae9f 182 Gene3D G3DSA:1.10.10.10 98 161 9.6E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14765 2a972169f79252622d72b85da66fae9f 182 Gene3D G3DSA:1.10.1740.10 4 79 2.2E-13 T 06-07-2017 SMD11_RS14765 2a972169f79252622d72b85da66fae9f 182 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 35 66 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS14765 2a972169f79252622d72b85da66fae9f 182 Pfam PF04542 Sigma-70 region 2 18 79 1.3E-7 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS14765 2a972169f79252622d72b85da66fae9f 182 Pfam PF08281 Sigma-70, region 4 105 156 4.3E-17 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS22690 9450757c158b34f327e26a4cde02c8d7 170 SUPERFAMILY SSF53933 58 165 2.04E-13 T 06-07-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 SMD11_RS22690 9450757c158b34f327e26a4cde02c8d7 170 Pfam PF00545 ribonuclease 106 163 6.4E-13 T 06-07-2017 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 SMD11_RS22690 9450757c158b34f327e26a4cde02c8d7 170 Gene3D G3DSA:3.10.450.30 106 166 2.0E-15 T 06-07-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 SMD11_RS12575 b2813a1cf264014291c655ca70f89c27 406 Gene3D G3DSA:3.30.70.1230 225 404 1.5E-20 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SMD11_RS12575 b2813a1cf264014291c655ca70f89c27 406 SUPERFAMILY SSF55073 224 402 2.51E-30 T 06-07-2017 IPR029787 Nucleotide cyclase SMD11_RS12575 b2813a1cf264014291c655ca70f89c27 406 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 226 355 6.4E-13 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SMD11_RS12575 b2813a1cf264014291c655ca70f89c27 406 Pfam PF16701 Adenylate cyclase regulatory domain 75 195 1.4E-7 T 06-07-2017 IPR032026 Adenylate cyclase regulatory domain SMD11_RS12575 b2813a1cf264014291c655ca70f89c27 406 SMART SM00044 111 367 9.5E-4 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SMD11_RS26360 fb8d8236ad8215f749b96d6afa8c1c42 330 SUPERFAMILY SSF143865 4 262 1.7E-69 T 06-07-2017 SMD11_RS26360 fb8d8236ad8215f749b96d6afa8c1c42 330 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 27 330 6.0E-63 T 06-07-2017 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 SMD11_RS26360 fb8d8236ad8215f749b96d6afa8c1c42 330 Pfam PF01544 CorA-like Mg2+ transporter protein 36 326 1.8E-63 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SMD11_RS26360 fb8d8236ad8215f749b96d6afa8c1c42 330 Gene3D G3DSA:3.30.460.20 3 137 3.9E-45 T 06-07-2017 SMD11_RS26360 fb8d8236ad8215f749b96d6afa8c1c42 330 SUPERFAMILY SSF144083 265 327 1.57E-19 T 06-07-2017 SMD11_RS26360 fb8d8236ad8215f749b96d6afa8c1c42 330 Gene3D G3DSA:1.20.58.340 254 330 2.6E-26 T 06-07-2017 SMD11_RS26360 fb8d8236ad8215f749b96d6afa8c1c42 330 Gene3D G3DSA:1.20.58.340 138 251 7.1E-38 T 06-07-2017 SMD11_RS20785 eb0c49ff9a0db64b5a94aa506e0c33a8 685 SUPERFAMILY SSF55874 401 570 9.82E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS20785 eb0c49ff9a0db64b5a94aa506e0c33a8 685 SMART SM00387 457 568 2.6E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS20785 eb0c49ff9a0db64b5a94aa506e0c33a8 685 Pfam PF00512 His Kinase A (phospho-acceptor) domain 344 411 1.3E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS20785 eb0c49ff9a0db64b5a94aa506e0c33a8 685 SUPERFAMILY SSF158472 284 332 9.68E-7 T 06-07-2017 SMD11_RS20785 eb0c49ff9a0db64b5a94aa506e0c33a8 685 SMART SM00304 284 336 7.1E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS20785 eb0c49ff9a0db64b5a94aa506e0c33a8 685 Pfam PF00672 HAMP domain 265 332 1.1E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS20785 eb0c49ff9a0db64b5a94aa506e0c33a8 685 SUPERFAMILY SSF47384 327 411 2.55E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS20785 eb0c49ff9a0db64b5a94aa506e0c33a8 685 Gene3D G3DSA:3.30.565.10 414 567 9.6E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS20785 eb0c49ff9a0db64b5a94aa506e0c33a8 685 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 458 567 5.1E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS20785 eb0c49ff9a0db64b5a94aa506e0c33a8 685 Gene3D G3DSA:1.10.287.130 335 407 8.0E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS20785 eb0c49ff9a0db64b5a94aa506e0c33a8 685 SMART SM00388 344 411 1.7E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS20785 eb0c49ff9a0db64b5a94aa506e0c33a8 685 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 507 6.4E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS20785 eb0c49ff9a0db64b5a94aa506e0c33a8 685 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 565 6.4E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS20785 eb0c49ff9a0db64b5a94aa506e0c33a8 685 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 546 6.4E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS20785 eb0c49ff9a0db64b5a94aa506e0c33a8 685 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 521 6.4E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS02655 36e004c4f77eea597a8dd1d24879d248 456 Gene3D G3DSA:3.40.605.10 7 246 5.1E-66 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS02655 36e004c4f77eea597a8dd1d24879d248 456 Pfam PF00171 Aldehyde dehydrogenase family 6 451 1.6E-123 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS02655 36e004c4f77eea597a8dd1d24879d248 456 Gene3D G3DSA:3.40.309.10 247 431 1.8E-51 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS02655 36e004c4f77eea597a8dd1d24879d248 456 SUPERFAMILY SSF53720 7 453 4.19E-125 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS02655 36e004c4f77eea597a8dd1d24879d248 456 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 259 270 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS02655 36e004c4f77eea597a8dd1d24879d248 456 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 231 238 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS12580 03b56e3a2815e0bb83de391c27ee8fb6 292 Gene3D G3DSA:3.30.930.10 33 225 1.6E-51 T 06-07-2017 SMD11_RS12580 03b56e3a2815e0bb83de391c27ee8fb6 292 Pfam PF03099 Biotin/lipoate A/B protein ligase family 63 172 6.8E-8 T 06-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 SMD11_RS12580 03b56e3a2815e0bb83de391c27ee8fb6 292 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 41 284 2.9E-39 T 06-07-2017 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS12580 03b56e3a2815e0bb83de391c27ee8fb6 292 SUPERFAMILY SSF55681 32 228 7.46E-44 T 06-07-2017 SMD11_RS12580 03b56e3a2815e0bb83de391c27ee8fb6 292 Gene3D G3DSA:2.30.30.100 238 282 5.8E-4 T 06-07-2017 SMD11_RS12580 03b56e3a2815e0bb83de391c27ee8fb6 292 Pfam PF02237 Biotin protein ligase C terminal domain 237 284 1.3E-10 T 06-07-2017 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 Gene3D G3DSA:3.40.1110.10 562 670 4.8E-21 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 Gene3D G3DSA:3.40.1110.10 421 482 4.8E-21 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 Pfam PF00689 Cation transporting ATPase, C-terminus 847 1015 1.3E-8 T 06-07-2017 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 SMART SM00831 21 94 2.5E-11 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 SUPERFAMILY SSF81653 145 204 1.07E-20 T 06-07-2017 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 SUPERFAMILY SSF81653 272 309 1.07E-20 T 06-07-2017 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 418 424 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 Pfam PF00702 haloacid dehalogenase-like hydrolase 412 778 1.1E-14 T 06-07-2017 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 764 783 2.6E-24 T 06-07-2017 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 416 430 2.6E-24 T 06-07-2017 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 686 696 2.6E-24 T 06-07-2017 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 787 799 2.6E-24 T 06-07-2017 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 185 199 2.6E-24 T 06-07-2017 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 731 853 2.0E-26 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 Gene3D G3DSA:1.20.1110.10 74 129 2.4E-52 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 Gene3D G3DSA:1.20.1110.10 733 973 2.4E-52 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 Pfam PF00690 Cation transporter/ATPase, N-terminus 27 89 6.1E-11 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 SUPERFAMILY SSF56784 414 434 5.34E-38 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 SUPERFAMILY SSF56784 620 864 5.34E-38 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 Pfam PF00122 E1-E2 ATPase 100 406 1.3E-42 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 Gene3D G3DSA:1.20.1110.10 234 235 2.1E-26 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 Gene3D G3DSA:1.20.1110.10 179 199 2.1E-26 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 Gene3D G3DSA:1.20.1110.10 274 420 2.1E-26 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 SUPERFAMILY SSF81665 29 132 3.01E-65 T 06-07-2017 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 SUPERFAMILY SSF81665 316 410 3.01E-65 T 06-07-2017 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 SUPERFAMILY SSF81665 813 1008 3.01E-65 T 06-07-2017 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 623 641 7.5E-13 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 736 752 7.5E-13 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 795 820 7.5E-13 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS11165 0eeee53504cda963634dbae5d158b308 1030 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 764 780 7.5E-13 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS33600 49a2560ad4a589a32c0cce7c4a9ec7c8 465 Gene3D G3DSA:3.40.640.10 71 317 5.2E-63 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS33600 49a2560ad4a589a32c0cce7c4a9ec7c8 465 Gene3D G3DSA:3.90.1150.10 318 437 1.4E-5 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS33600 49a2560ad4a589a32c0cce7c4a9ec7c8 465 SUPERFAMILY SSF53383 45 374 5.23E-75 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS33600 49a2560ad4a589a32c0cce7c4a9ec7c8 465 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 72 360 4.9E-22 T 06-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 SMD11_RS05760 da7a039230872009f1e2a280e9136801 200 PRINTS PR00598 Bacterial regulatory protein MarR family signature 147 163 4.1E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS05760 da7a039230872009f1e2a280e9136801 200 PRINTS PR00598 Bacterial regulatory protein MarR family signature 128 143 4.1E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS05760 da7a039230872009f1e2a280e9136801 200 PRINTS PR00598 Bacterial regulatory protein MarR family signature 177 197 4.1E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS05760 da7a039230872009f1e2a280e9136801 200 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 127 4.1E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS05760 da7a039230872009f1e2a280e9136801 200 Pfam PF12802 MarR family 93 150 2.3E-10 T 06-07-2017 SMD11_RS05760 da7a039230872009f1e2a280e9136801 200 SUPERFAMILY SSF46785 61 199 2.86E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05760 da7a039230872009f1e2a280e9136801 200 Gene3D G3DSA:1.10.10.10 70 199 3.2E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05760 da7a039230872009f1e2a280e9136801 200 SMART SM00347 87 187 2.4E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS23945 c59557d477018c17a778dac75e51386f 422 Pfam PF07730 Histidine kinase 228 295 2.0E-14 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS23945 c59557d477018c17a778dac75e51386f 422 Pfam PF13796 Putative sensor 18 199 3.5E-19 T 06-07-2017 IPR025828 Putative sensor domain SMD11_RS23945 c59557d477018c17a778dac75e51386f 422 Gene3D G3DSA:3.30.565.10 335 419 3.1E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS23945 c59557d477018c17a778dac75e51386f 422 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 377 7.5E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS23945 c59557d477018c17a778dac75e51386f 422 SUPERFAMILY SSF55874 306 419 3.54E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS23945 c59557d477018c17a778dac75e51386f 422 SMART SM00387 328 421 9.2E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS09860 d8123452873083f14cd25eac3395655c 471 Gene3D G3DSA:3.40.50.620 177 231 1.5E-34 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS09860 d8123452873083f14cd25eac3395655c 471 Gene3D G3DSA:3.40.50.620 1 51 1.5E-34 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS09860 d8123452873083f14cd25eac3395655c 471 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 1 304 6.1E-79 T 06-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 SMD11_RS09860 d8123452873083f14cd25eac3395655c 471 Gene3D G3DSA:1.10.1160.10 234 316 3.9E-30 T 06-07-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 SMD11_RS09860 d8123452873083f14cd25eac3395655c 471 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 1 464 2.0E-129 T 06-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMD11_RS09860 d8123452873083f14cd25eac3395655c 471 SUPERFAMILY SSF52374 1 300 1.46E-94 T 06-07-2017 SMD11_RS09860 d8123452873083f14cd25eac3395655c 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 4 15 5.4E-15 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SMD11_RS09860 d8123452873083f14cd25eac3395655c 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 175 185 5.4E-15 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SMD11_RS09860 d8123452873083f14cd25eac3395655c 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 19 32 5.4E-15 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SMD11_RS09860 d8123452873083f14cd25eac3395655c 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 191 199 5.4E-15 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SMD11_RS09860 d8123452873083f14cd25eac3395655c 471 SUPERFAMILY SSF48163 301 466 1.24E-34 T 06-07-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMD11_RS09860 d8123452873083f14cd25eac3395655c 471 Gene3D G3DSA:3.90.800.10 52 175 5.8E-40 T 06-07-2017 SMD11_RS09860 d8123452873083f14cd25eac3395655c 471 Gene3D G3DSA:1.10.10.350 371 466 3.9E-23 T 06-07-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMD11_RS09860 d8123452873083f14cd25eac3395655c 471 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 1 466 28.457 T 06-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SMD11_RS32455 ed961391b45af9e101a1f9a41ee183b9 99 Gene3D G3DSA:1.10.1200.10 9 80 1.0E-5 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS32455 ed961391b45af9e101a1f9a41ee183b9 99 SUPERFAMILY SSF47336 4 82 9.81E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS14820 67f418790e3cd5c7970f244f67b73b8c 172 Pfam PF00583 Acetyltransferase (GNAT) family 56 125 1.6E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS14820 67f418790e3cd5c7970f244f67b73b8c 172 Gene3D G3DSA:3.40.630.30 8 150 1.5E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS14820 67f418790e3cd5c7970f244f67b73b8c 172 SUPERFAMILY SSF55729 7 132 2.92E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS30330 32040d3f27da82fdbfd1a1116c6177ac 351 SUPERFAMILY SSF48576 6 327 5.47E-36 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS30330 32040d3f27da82fdbfd1a1116c6177ac 351 Gene3D G3DSA:1.10.600.10 5 318 1.4E-70 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS23765 cb5363086a9adb25ddc014532dc4868b 234 Gene3D G3DSA:3.40.50.720 26 227 5.8E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS23765 cb5363086a9adb25ddc014532dc4868b 234 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 26 117 2.4E-23 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SMD11_RS23765 cb5363086a9adb25ddc014532dc4868b 234 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 24 231 4.5E-78 T 06-07-2017 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 SMD11_RS23765 cb5363086a9adb25ddc014532dc4868b 234 SUPERFAMILY SSF51735 26 228 6.09E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06215 7ee24c97a00f83d8b819e352ecf0dd71 697 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 25 133 1.1E-7 T 06-07-2017 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV SMD11_RS06215 7ee24c97a00f83d8b819e352ecf0dd71 697 Gene3D G3DSA:3.40.720.10 295 459 7.9E-11 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMD11_RS06215 7ee24c97a00f83d8b819e352ecf0dd71 697 Gene3D G3DSA:3.40.720.10 171 261 7.9E-11 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMD11_RS06215 7ee24c97a00f83d8b819e352ecf0dd71 697 SUPERFAMILY SSF53649 578 626 7.41E-14 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMD11_RS06215 7ee24c97a00f83d8b819e352ecf0dd71 697 SUPERFAMILY SSF53649 170 348 7.41E-14 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMD11_RS06215 7ee24c97a00f83d8b819e352ecf0dd71 697 SUPERFAMILY SSF53649 377 539 7.41E-14 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMD11_RS06215 7ee24c97a00f83d8b819e352ecf0dd71 697 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 400 475 1.7E-5 T 06-07-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 SMD11_RS33620 1d079b76711f1058aa4ca5d966e113be 470 Gene3D G3DSA:1.10.630.10 336 426 5.3E-18 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS33620 1d079b76711f1058aa4ca5d966e113be 470 PRINTS PR00465 E-class P450 group IV signature 382 400 1.4E-8 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS33620 1d079b76711f1058aa4ca5d966e113be 470 PRINTS PR00465 E-class P450 group IV signature 405 421 1.4E-8 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS33620 1d079b76711f1058aa4ca5d966e113be 470 PRINTS PR00465 E-class P450 group IV signature 366 380 1.4E-8 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS33620 1d079b76711f1058aa4ca5d966e113be 470 PRINTS PR00465 E-class P450 group IV signature 333 349 1.4E-8 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS33620 1d079b76711f1058aa4ca5d966e113be 470 Pfam PF00067 Cytochrome P450 336 416 6.8E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS33620 1d079b76711f1058aa4ca5d966e113be 470 SUPERFAMILY SSF48264 316 428 3.27E-18 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS23390 c6dc4282700a7b7cbcd02c50dbdf2436 188 SMART SM00866 35 179 4.0E-20 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS23390 c6dc4282700a7b7cbcd02c50dbdf2436 188 Pfam PF07702 UTRA domain 42 178 8.0E-28 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS23390 c6dc4282700a7b7cbcd02c50dbdf2436 188 SUPERFAMILY SSF64288 42 184 1.57E-31 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS23390 c6dc4282700a7b7cbcd02c50dbdf2436 188 Gene3D G3DSA:3.40.1410.10 10 182 8.2E-53 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS18355 6e36bbe172eed81e6dadbca803e9683d 245 Gene3D G3DSA:1.10.10.10 180 234 4.2E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS18355 6e36bbe172eed81e6dadbca803e9683d 245 Gene3D G3DSA:3.30.450.40 6 174 2.7E-20 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS18355 6e36bbe172eed81e6dadbca803e9683d 245 Pfam PF03861 ANTAR domain 180 233 7.8E-16 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 SMD11_RS18355 6e36bbe172eed81e6dadbca803e9683d 245 SMART SM01012 178 233 6.8E-15 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 SMD11_RS18355 6e36bbe172eed81e6dadbca803e9683d 245 SMART SM00065 26 176 4.6E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS18355 6e36bbe172eed81e6dadbca803e9683d 245 SUPERFAMILY SSF52172 158 233 2.98E-7 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS18355 6e36bbe172eed81e6dadbca803e9683d 245 SUPERFAMILY SSF55781 7 174 5.02E-20 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS18355 6e36bbe172eed81e6dadbca803e9683d 245 Pfam PF13185 GAF domain 27 166 4.2E-10 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS18355 6e36bbe172eed81e6dadbca803e9683d 245 PIRSF PIRSF036625 1 241 4.5E-55 T 06-07-2017 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative SMD11_RS02450 15bb08483f75fab1866faadb80672bfc 170 Pfam PF07883 Cupin domain 53 120 1.1E-16 T 06-07-2017 IPR013096 Cupin 2, conserved barrel SMD11_RS02450 15bb08483f75fab1866faadb80672bfc 170 SUPERFAMILY SSF51182 16 155 2.14E-26 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS02450 15bb08483f75fab1866faadb80672bfc 170 Gene3D G3DSA:2.60.120.10 24 166 9.3E-33 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS34515 d7c9a1e94edf8b27266f7cbb8635647e 92 Gene3D G3DSA:1.10.10.10 22 80 6.0E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS34515 d7c9a1e94edf8b27266f7cbb8635647e 92 SUPERFAMILY SSF88659 17 80 5.67E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS34515 d7c9a1e94edf8b27266f7cbb8635647e 92 Pfam PF08281 Sigma-70, region 4 26 76 6.0E-14 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS02380 8c5dcb833ca3882eacd625f2c219e60d 218 Pfam PF01810 LysE type translocator 14 215 3.5E-35 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 SMD11_RS02380 8c5dcb833ca3882eacd625f2c219e60d 218 SUPERFAMILY SSF103473 5 213 4.71E-7 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS02380 8c5dcb833ca3882eacd625f2c219e60d 218 PIRSF PIRSF006324 1 218 1.2E-52 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 SMD11_RS01910 d7219bb4493e68ac2a9ec772583a50fe 335 Gene3D G3DSA:3.30.870.10 163 253 5.6E-4 T 06-07-2017 SMD11_RS01910 d7219bb4493e68ac2a9ec772583a50fe 335 SUPERFAMILY SSF46894 266 328 1.63E-8 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS01910 d7219bb4493e68ac2a9ec772583a50fe 335 Pfam PF00196 Bacterial regulatory proteins, luxR family 274 318 1.3E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS01910 d7219bb4493e68ac2a9ec772583a50fe 335 SMART SM00421 265 322 5.7E-4 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS01910 d7219bb4493e68ac2a9ec772583a50fe 335 Gene3D G3DSA:1.10.10.10 274 327 2.0E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS25560 e5fe40b9850132098c9af057f4df5844 522 SUPERFAMILY SSF111283 28 513 4.45E-93 T 06-07-2017 SMD11_RS25560 e5fe40b9850132098c9af057f4df5844 522 Pfam PF01523 Putative modulator of DNA gyrase 47 362 6.5E-50 T 06-07-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SMD11_RS22260 418768e3ca2d5cc2eec01b0a5d571ef0 269 SMART SM01232 122 214 1.0E-33 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD11_RS22260 418768e3ca2d5cc2eec01b0a5d571ef0 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 205 2.6E-21 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD11_RS22260 418768e3ca2d5cc2eec01b0a5d571ef0 269 Pfam PF06827 Zinc finger found in FPG and IleRS 241 269 4.2E-8 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 SMD11_RS22260 418768e3ca2d5cc2eec01b0a5d571ef0 269 ProSitePatterns PS01242 Zinc finger FPG-type signature. 243 267 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 SMD11_RS22260 418768e3ca2d5cc2eec01b0a5d571ef0 269 Gene3D G3DSA:3.20.190.10 2 122 3.4E-17 T 06-07-2017 SMD11_RS22260 418768e3ca2d5cc2eec01b0a5d571ef0 269 SMART SM00898 2 108 3.1E-23 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD11_RS22260 418768e3ca2d5cc2eec01b0a5d571ef0 269 SUPERFAMILY SSF81624 2 123 2.75E-25 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD11_RS22260 418768e3ca2d5cc2eec01b0a5d571ef0 269 Gene3D G3DSA:1.10.8.50 123 268 7.7E-44 T 06-07-2017 SMD11_RS22260 418768e3ca2d5cc2eec01b0a5d571ef0 269 SUPERFAMILY SSF57716 220 267 1.9E-12 T 06-07-2017 SMD11_RS22260 418768e3ca2d5cc2eec01b0a5d571ef0 269 SUPERFAMILY SSF46946 121 205 1.23E-24 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMD11_RS22260 418768e3ca2d5cc2eec01b0a5d571ef0 269 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 103 4.3E-9 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD11_RS21960 d696d685d2b5ceb0e6f87a07fcdca0e8 298 SUPERFAMILY SSF48576 9 218 1.04E-18 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS21960 d696d685d2b5ceb0e6f87a07fcdca0e8 298 Gene3D G3DSA:1.10.600.10 3 146 5.1E-21 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS21960 d696d685d2b5ceb0e6f87a07fcdca0e8 298 Pfam PF00348 Polyprenyl synthetase 34 144 7.7E-13 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 SMD11_RS04450 e1476334c5e564817226361a9165c24b 312 SUPERFAMILY SSF56601 44 294 2.89E-59 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS04450 e1476334c5e564817226361a9165c24b 312 Gene3D G3DSA:3.40.710.10 43 294 9.3E-75 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS04450 e1476334c5e564817226361a9165c24b 312 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 159 172 5.0E-14 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD11_RS04450 e1476334c5e564817226361a9165c24b 312 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 126 143 5.0E-14 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD11_RS04450 e1476334c5e564817226361a9165c24b 312 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 72 83 5.0E-14 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD11_RS04450 e1476334c5e564817226361a9165c24b 312 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 37 277 5.2E-46 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SMD11_RS21930 e5c2d52f47208aa9c7d3115014de53e6 234 SUPERFAMILY SSF81343 5 233 1.0E-50 T 06-07-2017 SMD11_RS21930 e5c2d52f47208aa9c7d3115014de53e6 234 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 20 233 5.9E-72 T 06-07-2017 IPR011138 Succinate dehydrogenase cytochrome b558 subunit SMD11_RS21930 e5c2d52f47208aa9c7d3115014de53e6 234 Gene3D G3DSA:1.20.950.10 28 223 3.0E-13 T 06-07-2017 SMD11_RS21930 e5c2d52f47208aa9c7d3115014de53e6 234 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 117 218 2.2E-7 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS25990 62de2cf4119201aec2bb08dcb8558ab5 267 Pfam PF07920 Protein of unknown function (DUF1684) 129 264 1.9E-36 T 06-07-2017 IPR012467 Protein of unknown function DUF1684 SMD11_RS04740 a9b4b7d8a001b01aee6f9d083e5198f6 209 Pfam PF03458 UPF0126 domain 91 164 2.3E-19 T 06-07-2017 IPR005115 Uncharacterised domain UPF0126 SMD11_RS04740 a9b4b7d8a001b01aee6f9d083e5198f6 209 Pfam PF03458 UPF0126 domain 4 76 7.8E-17 T 06-07-2017 IPR005115 Uncharacterised domain UPF0126 SMD11_RS23905 a965fa58c9c25a51a49404b68904407a 458 Pfam PF00128 Alpha amylase, catalytic domain 85 333 2.2E-16 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS23905 a965fa58c9c25a51a49404b68904407a 458 Gene3D G3DSA:3.20.20.80 26 374 5.9E-104 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS23905 a965fa58c9c25a51a49404b68904407a 458 SUPERFAMILY SSF51011 375 455 1.8E-25 T 06-07-2017 SMD11_RS23905 a965fa58c9c25a51a49404b68904407a 458 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 382 448 2.5E-8 T 06-07-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 SMD11_RS23905 a965fa58c9c25a51a49404b68904407a 458 PRINTS PR00110 Alpha-amylase signature 284 296 1.5E-22 T 06-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 SMD11_RS23905 a965fa58c9c25a51a49404b68904407a 458 PRINTS PR00110 Alpha-amylase signature 108 119 1.5E-22 T 06-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 SMD11_RS23905 a965fa58c9c25a51a49404b68904407a 458 PRINTS PR00110 Alpha-amylase signature 226 244 1.5E-22 T 06-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 SMD11_RS23905 a965fa58c9c25a51a49404b68904407a 458 PRINTS PR00110 Alpha-amylase signature 197 208 1.5E-22 T 06-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 SMD11_RS23905 a965fa58c9c25a51a49404b68904407a 458 PRINTS PR00110 Alpha-amylase signature 76 93 1.5E-22 T 06-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 SMD11_RS23905 a965fa58c9c25a51a49404b68904407a 458 SUPERFAMILY SSF51445 26 372 2.07E-83 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS23905 a965fa58c9c25a51a49404b68904407a 458 Gene3D G3DSA:2.60.40.1180 376 452 2.8E-26 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta SMD11_RS23905 a965fa58c9c25a51a49404b68904407a 458 SMART SM00642 33 370 8.9E-75 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS23905 a965fa58c9c25a51a49404b68904407a 458 SMART SM00632 379 455 5.2E-34 T 06-07-2017 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 SMD11_RS31930 ecba34a81b94fe8f1cfc23b5999233bd 92 Pfam PF13560 Helix-turn-helix domain 17 76 4.0E-11 T 06-07-2017 SMD11_RS31930 ecba34a81b94fe8f1cfc23b5999233bd 92 SUPERFAMILY SSF47413 8 76 8.16E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS31930 ecba34a81b94fe8f1cfc23b5999233bd 92 Gene3D G3DSA:1.10.260.40 9 75 3.4E-25 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS31930 ecba34a81b94fe8f1cfc23b5999233bd 92 SMART SM00530 20 74 8.2E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS26465 b1a9bb57f2e99c67788740a401f63a81 530 SUPERFAMILY SSF53850 34 524 2.35E-90 T 06-07-2017 SMD11_RS26465 b1a9bb57f2e99c67788740a401f63a81 530 Gene3D G3DSA:3.90.76.10 49 204 4.0E-29 T 06-07-2017 SMD11_RS26465 b1a9bb57f2e99c67788740a401f63a81 530 Gene3D G3DSA:3.10.105.10 284 496 6.6E-41 T 06-07-2017 SMD11_RS26465 b1a9bb57f2e99c67788740a401f63a81 530 PIRSF PIRSF002741 9 522 1.1E-59 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD11_RS26465 b1a9bb57f2e99c67788740a401f63a81 530 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 445 6.1E-69 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain SMD11_RS08640 1c89b6a966942160199a082351a0029b 449 Pfam PF00675 Insulinase (Peptidase family M16) 26 164 1.9E-21 T 06-07-2017 IPR011765 Peptidase M16, N-terminal SMD11_RS08640 1c89b6a966942160199a082351a0029b 449 SUPERFAMILY SSF63411 17 229 2.93E-59 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMD11_RS08640 1c89b6a966942160199a082351a0029b 449 Gene3D G3DSA:3.30.830.10 19 236 3.1E-59 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 SMD11_RS08640 1c89b6a966942160199a082351a0029b 449 Pfam PF05193 Peptidase M16 inactive domain 185 364 6.0E-30 T 06-07-2017 IPR007863 Peptidase M16, C-terminal SMD11_RS08640 1c89b6a966942160199a082351a0029b 449 Gene3D G3DSA:3.30.830.10 254 427 2.4E-17 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 SMD11_RS08640 1c89b6a966942160199a082351a0029b 449 SUPERFAMILY SSF63411 248 439 5.5E-26 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SMD11_RS24800 0c62ff23708a65d81f3a5468ba082c83 397 Gene3D G3DSA:3.40.50.2000 211 367 3.6E-52 T 06-07-2017 SMD11_RS24800 0c62ff23708a65d81f3a5468ba082c83 397 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 11 367 1.3E-131 T 06-07-2017 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 SMD11_RS24800 0c62ff23708a65d81f3a5468ba082c83 397 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 31 366 5.7E-111 T 06-07-2017 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS24800 0c62ff23708a65d81f3a5468ba082c83 397 SUPERFAMILY SSF53756 10 368 1.91E-117 T 06-07-2017 SMD11_RS24800 0c62ff23708a65d81f3a5468ba082c83 397 Gene3D G3DSA:3.40.50.2000 10 210 1.6E-73 T 06-07-2017 SMD11_RS20350 7570164d650a845656bf012aa4fa4cac 469 Gene3D G3DSA:1.10.630.10 16 460 1.7E-121 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20350 7570164d650a845656bf012aa4fa4cac 469 SUPERFAMILY SSF48264 15 459 4.45E-112 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20350 7570164d650a845656bf012aa4fa4cac 469 Pfam PF00067 Cytochrome P450 18 443 1.6E-90 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20350 7570164d650a845656bf012aa4fa4cac 469 PRINTS PR00463 E-class P450 group I signature 44 63 3.7E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20350 7570164d650a845656bf012aa4fa4cac 469 PRINTS PR00463 E-class P450 group I signature 399 409 3.7E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20350 7570164d650a845656bf012aa4fa4cac 469 PRINTS PR00463 E-class P450 group I signature 362 386 3.7E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20350 7570164d650a845656bf012aa4fa4cac 469 PRINTS PR00463 E-class P450 group I signature 280 306 3.7E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20350 7570164d650a845656bf012aa4fa4cac 469 PRINTS PR00463 E-class P450 group I signature 409 432 3.7E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20350 7570164d650a845656bf012aa4fa4cac 469 PRINTS PR00463 E-class P450 group I signature 260 277 3.7E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20350 7570164d650a845656bf012aa4fa4cac 469 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 402 411 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS20350 7570164d650a845656bf012aa4fa4cac 469 PRINTS PR00385 P450 superfamily signature 271 288 1.1E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20350 7570164d650a845656bf012aa4fa4cac 469 PRINTS PR00385 P450 superfamily signature 409 420 1.1E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20350 7570164d650a845656bf012aa4fa4cac 469 PRINTS PR00385 P450 superfamily signature 323 334 1.1E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20350 7570164d650a845656bf012aa4fa4cac 469 PRINTS PR00385 P450 superfamily signature 400 409 1.1E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS24765 6f8b2d34f212993570c504bbca08e7f0 271 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 18 266 34.246 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD11_RS24765 6f8b2d34f212993570c504bbca08e7f0 271 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 52 65 - T 06-07-2017 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD11_RS24765 6f8b2d34f212993570c504bbca08e7f0 271 Pfam PF00290 Tryptophan synthase alpha chain 13 264 3.9E-78 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD11_RS24765 6f8b2d34f212993570c504bbca08e7f0 271 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 14 262 2.1E-67 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 SMD11_RS24765 6f8b2d34f212993570c504bbca08e7f0 271 SUPERFAMILY SSF51366 8 245 5.73E-80 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMD11_RS24765 6f8b2d34f212993570c504bbca08e7f0 271 Gene3D G3DSA:3.20.20.70 9 269 2.5E-94 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS01010 19df5559e323c6fd8ee4622e31a17da2 510 Gene3D G3DSA:3.40.50.980 14 166 2.7E-24 T 06-07-2017 SMD11_RS01010 19df5559e323c6fd8ee4622e31a17da2 510 SUPERFAMILY SSF56801 9 507 8.5E-106 T 06-07-2017 SMD11_RS01010 19df5559e323c6fd8ee4622e31a17da2 510 Gene3D G3DSA:3.30.300.30 410 505 1.0E-21 T 06-07-2017 SMD11_RS01010 19df5559e323c6fd8ee4622e31a17da2 510 Gene3D G3DSA:2.30.38.10 334 405 8.8E-21 T 06-07-2017 SMD11_RS01010 19df5559e323c6fd8ee4622e31a17da2 510 Pfam PF00501 AMP-binding enzyme 15 412 2.1E-66 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS01010 19df5559e323c6fd8ee4622e31a17da2 510 ProSitePatterns PS00455 Putative AMP-binding domain signature. 161 172 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS01010 19df5559e323c6fd8ee4622e31a17da2 510 Gene3D G3DSA:3.40.50.980 167 333 7.6E-21 T 06-07-2017 SMD11_RS01010 19df5559e323c6fd8ee4622e31a17da2 510 Pfam PF13193 AMP-binding enzyme C-terminal domain 423 496 1.7E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS22845 2b6c46c781146252bf9b22a575a2815d 309 SUPERFAMILY SSF50129 5 141 9.13E-21 T 06-07-2017 IPR011032 GroES-like SMD11_RS22845 2b6c46c781146252bf9b22a575a2815d 309 SMART SM00829 9 306 8.1E-8 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS22845 2b6c46c781146252bf9b22a575a2815d 309 SUPERFAMILY SSF51735 111 279 3.53E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS22845 2b6c46c781146252bf9b22a575a2815d 309 Gene3D G3DSA:3.90.180.10 1 138 1.0E-23 T 06-07-2017 IPR011032 GroES-like SMD11_RS22845 2b6c46c781146252bf9b22a575a2815d 309 Pfam PF13602 Zinc-binding dehydrogenase 179 306 1.4E-8 T 06-07-2017 SMD11_RS22845 2b6c46c781146252bf9b22a575a2815d 309 Gene3D G3DSA:3.40.50.720 139 240 6.9E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04405 d546334c323f030c74e918d238318f25 530 SUPERFAMILY SSF52540 15 236 8.31E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04405 d546334c323f030c74e918d238318f25 530 Gene3D G3DSA:3.40.50.300 14 235 1.2E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04405 d546334c323f030c74e918d238318f25 530 Gene3D G3DSA:3.40.50.300 259 502 1.7E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04405 d546334c323f030c74e918d238318f25 530 SUPERFAMILY SSF52540 268 495 1.5E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04405 d546334c323f030c74e918d238318f25 530 SMART SM00382 296 490 1.7E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS04405 d546334c323f030c74e918d238318f25 530 SMART SM00382 40 229 9.3E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS04405 d546334c323f030c74e918d238318f25 530 ProSitePatterns PS00211 ABC transporters family signature. 414 428 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS04405 d546334c323f030c74e918d238318f25 530 Pfam PF00005 ABC transporter 288 441 1.7E-19 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS04405 d546334c323f030c74e918d238318f25 530 Pfam PF00005 ABC transporter 31 181 9.6E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS15870 fceceb257c8a43bd0f427e4bf36e9d86 418 SUPERFAMILY SSF56059 97 314 1.06E-34 T 06-07-2017 SMD11_RS15870 fceceb257c8a43bd0f427e4bf36e9d86 418 Pfam PF13535 ATP-grasp domain 143 279 5.8E-10 T 06-07-2017 SMD11_RS15870 fceceb257c8a43bd0f427e4bf36e9d86 418 Gene3D G3DSA:3.30.470.20 101 342 1.1E-26 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS21480 26eb0901cce2ae9fe3b2a67c76788915 245 TIGRFAM TIGR03351 PhnX-like: phosphonatase-like hydrolase 17 238 1.5E-70 T 06-07-2017 IPR022468 Phosphonatase-like hydrolase SMD11_RS21480 26eb0901cce2ae9fe3b2a67c76788915 245 SUPERFAMILY SSF56784 17 239 3.84E-36 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS21480 26eb0901cce2ae9fe3b2a67c76788915 245 Gene3D G3DSA:3.40.50.1000 83 240 4.1E-29 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS21480 26eb0901cce2ae9fe3b2a67c76788915 245 Pfam PF00702 haloacid dehalogenase-like hydrolase 19 202 2.2E-10 T 06-07-2017 SMD11_RS13040 b9ada1e57e4098c9398ec2456016c36e 220 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 178 7.5E-18 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS13040 b9ada1e57e4098c9398ec2456016c36e 220 Pfam PF04542 Sigma-70 region 2 27 93 1.5E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS13040 b9ada1e57e4098c9398ec2456016c36e 220 SUPERFAMILY SSF88946 4 107 3.14E-24 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS13040 b9ada1e57e4098c9398ec2456016c36e 220 Gene3D G3DSA:1.10.10.10 126 180 4.0E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13040 b9ada1e57e4098c9398ec2456016c36e 220 SUPERFAMILY SSF88659 124 179 4.36E-9 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS13040 b9ada1e57e4098c9398ec2456016c36e 220 Pfam PF08281 Sigma-70, region 4 127 176 2.6E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS13040 b9ada1e57e4098c9398ec2456016c36e 220 Gene3D G3DSA:1.10.1740.10 6 115 2.5E-26 T 06-07-2017 SMD11_RS30235 08b24218a36c31c323822946a223420c 278 Gene3D G3DSA:3.40.50.720 27 277 3.2E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30235 08b24218a36c31c323822946a223420c 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 100 111 1.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30235 08b24218a36c31c323822946a223420c 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 192 1.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30235 08b24218a36c31c323822946a223420c 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 161 1.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30235 08b24218a36c31c323822946a223420c 278 SUPERFAMILY SSF51735 30 277 3.0E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30235 08b24218a36c31c323822946a223420c 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 4.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30235 08b24218a36c31c323822946a223420c 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 239 259 4.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30235 08b24218a36c31c323822946a223420c 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 163 4.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30235 08b24218a36c31c323822946a223420c 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 111 4.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30235 08b24218a36c31c323822946a223420c 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 33 50 4.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30235 08b24218a36c31c323822946a223420c 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 4.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30235 08b24218a36c31c323822946a223420c 278 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 32 278 6.4E-100 T 06-07-2017 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 SMD11_RS30235 08b24218a36c31c323822946a223420c 278 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 160 188 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS30235 08b24218a36c31c323822946a223420c 278 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 38 276 3.5E-49 T 06-07-2017 SMD11_RS00040 7171a4287c882b446fa5e379fe6f9420 286 SMART SM00530 21 93 8.6E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS00040 7171a4287c882b446fa5e379fe6f9420 286 SUPERFAMILY SSF47413 40 91 4.13E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS00040 7171a4287c882b446fa5e379fe6f9420 286 Gene3D G3DSA:1.10.260.40 11 92 2.8E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS00040 7171a4287c882b446fa5e379fe6f9420 286 Pfam PF13560 Helix-turn-helix domain 20 96 2.2E-16 T 06-07-2017 SMD11_RS06280 8a0714ed95411c7e555e052438421370 620 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 388 542 3.0E-30 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMD11_RS06280 8a0714ed95411c7e555e052438421370 620 SUPERFAMILY SSF52467 156 355 1.31E-38 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS06280 8a0714ed95411c7e555e052438421370 620 Gene3D G3DSA:3.40.50.1220 192 352 5.5E-37 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain SMD11_RS06280 8a0714ed95411c7e555e052438421370 620 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 425 444 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 SMD11_RS06280 8a0714ed95411c7e555e052438421370 620 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 328 3.7E-24 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SMD11_RS06280 8a0714ed95411c7e555e052438421370 620 Gene3D G3DSA:3.40.50.970 2 180 9.5E-57 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS06280 8a0714ed95411c7e555e052438421370 620 SUPERFAMILY SSF52518 364 560 2.14E-54 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS06280 8a0714ed95411c7e555e052438421370 620 SUPERFAMILY SSF52518 4 181 2.83E-46 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS06280 8a0714ed95411c7e555e052438421370 620 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 171 8.4E-45 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SMD11_RS06280 8a0714ed95411c7e555e052438421370 620 Gene3D G3DSA:3.40.50.970 362 563 3.1E-54 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS33370 e53bc736ac65d3d79ea01b1dbf8f4e56 195 SUPERFAMILY SSF53254 1 183 1.05E-27 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS33370 e53bc736ac65d3d79ea01b1dbf8f4e56 195 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 175 6.3E-19 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS33370 e53bc736ac65d3d79ea01b1dbf8f4e56 195 Gene3D G3DSA:3.40.50.1240 4 181 7.3E-21 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS32635 cbc44c527180931ab8d6e2f7073addd2 434 Gene3D G3DSA:1.10.630.10 17 432 9.3E-82 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS32635 cbc44c527180931ab8d6e2f7073addd2 434 SUPERFAMILY SSF48264 27 418 6.29E-64 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS32635 cbc44c527180931ab8d6e2f7073addd2 434 Pfam PF00067 Cytochrome P450 305 398 3.5E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS32635 cbc44c527180931ab8d6e2f7073addd2 434 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 373 382 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS32635 cbc44c527180931ab8d6e2f7073addd2 434 PRINTS PR00359 B-class P450 signature 156 172 2.7E-16 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32635 cbc44c527180931ab8d6e2f7073addd2 434 PRINTS PR00359 B-class P450 signature 380 391 2.7E-16 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32635 cbc44c527180931ab8d6e2f7073addd2 434 PRINTS PR00359 B-class P450 signature 321 348 2.7E-16 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32635 cbc44c527180931ab8d6e2f7073addd2 434 PRINTS PR00359 B-class P450 signature 371 380 2.7E-16 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32635 cbc44c527180931ab8d6e2f7073addd2 434 PRINTS PR00359 B-class P450 signature 349 364 2.7E-16 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32635 cbc44c527180931ab8d6e2f7073addd2 434 PRINTS PR00359 B-class P450 signature 304 315 2.7E-16 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS23470 d154839452ee308e069ec4f7e4f7d322 564 Gene3D G3DSA:3.40.50.300 316 531 1.9E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23470 d154839452ee308e069ec4f7e4f7d322 564 Gene3D G3DSA:3.40.50.300 2 227 1.8E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23470 d154839452ee308e069ec4f7e4f7d322 564 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS23470 d154839452ee308e069ec4f7e4f7d322 564 SUPERFAMILY SSF52540 310 531 9.13E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23470 d154839452ee308e069ec4f7e4f7d322 564 SMART SM00382 28 219 3.4E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS23470 d154839452ee308e069ec4f7e4f7d322 564 SMART SM00382 339 527 7.8E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS23470 d154839452ee308e069ec4f7e4f7d322 564 SUPERFAMILY SSF52540 1 231 6.49E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23470 d154839452ee308e069ec4f7e4f7d322 564 Pfam PF00005 ABC transporter 19 170 1.1E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS23470 d154839452ee308e069ec4f7e4f7d322 564 Pfam PF00005 ABC transporter 330 471 9.0E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS32525 39fc4b5296ddc45dd26528dc7687ffb1 399 Gene3D G3DSA:1.20.1250.20 201 384 2.4E-12 T 06-07-2017 SMD11_RS32525 39fc4b5296ddc45dd26528dc7687ffb1 399 Gene3D G3DSA:1.20.1250.20 6 184 5.0E-24 T 06-07-2017 SMD11_RS32525 39fc4b5296ddc45dd26528dc7687ffb1 399 SUPERFAMILY SSF103473 3 388 3.4E-54 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS32525 39fc4b5296ddc45dd26528dc7687ffb1 399 Pfam PF07690 Major Facilitator Superfamily 10 350 2.3E-41 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS04205 71f757f4d5c38518e3be8503ae211fba 370 Pfam PF00512 His Kinase A (phospho-acceptor) domain 150 214 3.5E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS04205 71f757f4d5c38518e3be8503ae211fba 370 Gene3D G3DSA:1.10.287.130 142 210 1.2E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS04205 71f757f4d5c38518e3be8503ae211fba 370 SUPERFAMILY SSF55874 204 367 2.01E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS04205 71f757f4d5c38518e3be8503ae211fba 370 SMART SM00387 259 369 2.9E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS04205 71f757f4d5c38518e3be8503ae211fba 370 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 261 367 7.5E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS04205 71f757f4d5c38518e3be8503ae211fba 370 SUPERFAMILY SSF47384 137 214 7.65E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS04205 71f757f4d5c38518e3be8503ae211fba 370 Gene3D G3DSA:3.30.565.10 216 368 1.4E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS04205 71f757f4d5c38518e3be8503ae211fba 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 310 4.1E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS04205 71f757f4d5c38518e3be8503ae211fba 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 348 4.1E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS04205 71f757f4d5c38518e3be8503ae211fba 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 366 4.1E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS04205 71f757f4d5c38518e3be8503ae211fba 370 SMART SM00388 150 214 1.5E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS33840 76e13f55a3ad086c0105821ff434ee87 346 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 247 263 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMD11_RS33840 76e13f55a3ad086c0105821ff434ee87 346 Gene3D G3DSA:3.40.50.720 130 309 5.4E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33840 76e13f55a3ad086c0105821ff434ee87 346 SUPERFAMILY SSF52283 48 156 2.98E-21 T 06-07-2017 SMD11_RS33840 76e13f55a3ad086c0105821ff434ee87 346 SUPERFAMILY SSF51735 124 308 5.33E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33840 76e13f55a3ad086c0105821ff434ee87 346 Gene3D G3DSA:3.40.50.720 46 129 3.1E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33840 76e13f55a3ad086c0105821ff434ee87 346 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 130 308 2.7E-55 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMD11_RS33840 76e13f55a3ad086c0105821ff434ee87 346 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 55 340 1.2E-16 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMD11_RS09495 c72aa54614b2aae1fc36764ad52d8b1d 368 Gene3D G3DSA:3.20.20.70 120 338 8.9E-16 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS09495 c72aa54614b2aae1fc36764ad52d8b1d 368 SUPERFAMILY SSF102114 113 342 6.67E-17 T 06-07-2017 SMD11_RS09495 c72aa54614b2aae1fc36764ad52d8b1d 368 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 20 367 1.6E-96 T 06-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD11_RS09495 c72aa54614b2aae1fc36764ad52d8b1d 368 PIRSF PIRSF006004 14 368 1.8E-124 T 06-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD11_RS09495 c72aa54614b2aae1fc36764ad52d8b1d 368 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 19 368 67.443 T 06-07-2017 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SMD11_RS09495 c72aa54614b2aae1fc36764ad52d8b1d 368 Pfam PF04055 Radical SAM superfamily 124 295 5.4E-16 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS17190 8391152d1a9bf36d2de1cf71598993d2 547 Pfam PF00994 Probable molybdopterin binding domain 328 462 1.8E-22 T 06-07-2017 IPR001453 MoaB/Mog domain SMD11_RS17190 8391152d1a9bf36d2de1cf71598993d2 547 Pfam PF03454 MoeA C-terminal region (domain IV) 475 529 1.5E-7 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS17190 8391152d1a9bf36d2de1cf71598993d2 547 Gene3D G3DSA:3.40.980.10 309 473 1.6E-43 T 06-07-2017 IPR001453 MoaB/Mog domain SMD11_RS17190 8391152d1a9bf36d2de1cf71598993d2 547 SMART SM00852 327 463 3.7E-28 T 06-07-2017 IPR001453 MoaB/Mog domain SMD11_RS17190 8391152d1a9bf36d2de1cf71598993d2 547 Gene3D G3DSA:2.170.190.11 190 288 8.6E-17 T 06-07-2017 SMD11_RS17190 8391152d1a9bf36d2de1cf71598993d2 547 SUPERFAMILY SSF63882 145 323 9.94E-35 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS17190 8391152d1a9bf36d2de1cf71598993d2 547 Gene3D G3DSA:3.90.105.10 171 189 1.7E-11 T 06-07-2017 SMD11_RS17190 8391152d1a9bf36d2de1cf71598993d2 547 Gene3D G3DSA:3.90.105.10 289 308 1.7E-11 T 06-07-2017 SMD11_RS17190 8391152d1a9bf36d2de1cf71598993d2 547 Pfam PF03453 MoeA N-terminal region (domain I and II) 159 314 8.9E-30 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS17190 8391152d1a9bf36d2de1cf71598993d2 547 SUPERFAMILY SSF53218 324 465 4.84E-29 T 06-07-2017 IPR001453 MoaB/Mog domain SMD11_RS17190 8391152d1a9bf36d2de1cf71598993d2 547 Gene3D G3DSA:2.40.340.10 474 527 1.3E-4 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS10170 1a0392b4d3a8e85c45d35793f83adcfb 244 Pfam PF01863 Protein of unknown function DUF45 29 232 2.8E-34 T 06-07-2017 IPR002725 Protein of unknown function DUF45 SMD11_RS10055 d555d1eb997ae627cce87c59507a8d18 534 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 11 318 4.1E-31 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMD11_RS10055 d555d1eb997ae627cce87c59507a8d18 534 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 286 3.4E-61 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMD11_RS10055 d555d1eb997ae627cce87c59507a8d18 534 Pfam PF01842 ACT domain 464 520 3.2E-10 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 SMD11_RS10055 d555d1eb997ae627cce87c59507a8d18 534 Gene3D G3DSA:3.30.1330.90 323 450 1.0E-41 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SMD11_RS10055 d555d1eb997ae627cce87c59507a8d18 534 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 197 219 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMD11_RS10055 d555d1eb997ae627cce87c59507a8d18 534 SUPERFAMILY SSF51735 107 286 6.93E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10055 d555d1eb997ae627cce87c59507a8d18 534 Gene3D G3DSA:3.30.70.260 451 529 8.1E-17 T 06-07-2017 SMD11_RS10055 d555d1eb997ae627cce87c59507a8d18 534 Gene3D G3DSA:3.40.50.720 8 112 2.1E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10055 d555d1eb997ae627cce87c59507a8d18 534 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SMD11_RS10055 d555d1eb997ae627cce87c59507a8d18 534 SUPERFAMILY SSF143548 325 454 1.26E-32 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SMD11_RS10055 d555d1eb997ae627cce87c59507a8d18 534 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMD11_RS10055 d555d1eb997ae627cce87c59507a8d18 534 SUPERFAMILY SSF52283 8 140 1.89E-35 T 06-07-2017 SMD11_RS10055 d555d1eb997ae627cce87c59507a8d18 534 Gene3D G3DSA:3.40.50.720 113 288 5.0E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10055 d555d1eb997ae627cce87c59507a8d18 534 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 11 532 2.6E-185 T 06-07-2017 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 SMD11_RS10055 d555d1eb997ae627cce87c59507a8d18 534 SUPERFAMILY SSF55021 459 531 4.58E-14 T 06-07-2017 SMD11_RS02390 8da6c764ad309af43656a360b0538edf 104 Gene3D G3DSA:1.10.287.1080 10 94 1.8E-5 T 06-07-2017 SMD11_RS02390 8da6c764ad309af43656a360b0538edf 104 SUPERFAMILY SSF101386 8 101 8.04E-10 T 06-07-2017 SMD11_RS02390 8da6c764ad309af43656a360b0538edf 104 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 32 96 1.9E-4 T 06-07-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core SMD11_RS25650 64277b83675569ca0850640496a27d1b 140 SUPERFAMILY SSF141322 73 139 2.62E-7 T 06-07-2017 SMD11_RS25650 64277b83675569ca0850640496a27d1b 140 Pfam PF01957 NfeD-like C-terminal, partner-binding 7 139 3.4E-18 T 06-07-2017 IPR002810 NfeD-like, C-terminal domain SMD11_RS25650 64277b83675569ca0850640496a27d1b 140 Gene3D G3DSA:2.40.50.140 81 140 2.6E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS25290 6345232aa878aacc0dda28eb3729d5d5 402 Pfam PF02342 TerD domain 23 161 5.5E-28 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS25290 6345232aa878aacc0dda28eb3729d5d5 402 Pfam PF02342 TerD domain 220 388 2.6E-38 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS25290 6345232aa878aacc0dda28eb3729d5d5 402 Gene3D G3DSA:2.60.60.30 238 390 3.2E-48 T 06-07-2017 SMD11_RS25290 6345232aa878aacc0dda28eb3729d5d5 402 Gene3D G3DSA:2.60.60.30 23 159 8.5E-27 T 06-07-2017 SMD11_RS33485 9dc5e59db0b5233f9c639c86375b9d86 232 SUPERFAMILY SSF51735 2 230 1.37E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33485 9dc5e59db0b5233f9c639c86375b9d86 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 1.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33485 9dc5e59db0b5233f9c639c86375b9d86 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 1.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33485 9dc5e59db0b5233f9c639c86375b9d86 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 1.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33485 9dc5e59db0b5233f9c639c86375b9d86 232 Gene3D G3DSA:3.40.50.720 2 230 2.4E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33485 9dc5e59db0b5233f9c639c86375b9d86 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 1.7E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33485 9dc5e59db0b5233f9c639c86375b9d86 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 1.7E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33485 9dc5e59db0b5233f9c639c86375b9d86 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 216 1.7E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33485 9dc5e59db0b5233f9c639c86375b9d86 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.7E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33485 9dc5e59db0b5233f9c639c86375b9d86 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 1.7E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33485 9dc5e59db0b5233f9c639c86375b9d86 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 1.7E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33485 9dc5e59db0b5233f9c639c86375b9d86 232 Pfam PF00106 short chain dehydrogenase 2 183 7.8E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS12705 a5a74cc0cb69ead722f6d7dd7db21c80 257 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 89 237 2.0E-24 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS12705 a5a74cc0cb69ead722f6d7dd7db21c80 257 SUPERFAMILY SSF88946 84 170 4.32E-16 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS12705 a5a74cc0cb69ead722f6d7dd7db21c80 257 Pfam PF08281 Sigma-70, region 4 185 236 6.0E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS12705 a5a74cc0cb69ead722f6d7dd7db21c80 257 Gene3D G3DSA:1.10.1740.10 83 158 1.1E-18 T 06-07-2017 SMD11_RS12705 a5a74cc0cb69ead722f6d7dd7db21c80 257 Gene3D G3DSA:1.10.10.10 179 238 5.0E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12705 a5a74cc0cb69ead722f6d7dd7db21c80 257 SUPERFAMILY SSF88659 177 238 1.33E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS12705 a5a74cc0cb69ead722f6d7dd7db21c80 257 Pfam PF04542 Sigma-70 region 2 95 158 2.8E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS12705 a5a74cc0cb69ead722f6d7dd7db21c80 257 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 83 239 5.4E-62 T 06-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMD11_RS20170 d0a917c0aeab4aa909530f62acd2109b 325 SMART SM01400 12 128 1.2E-69 T 06-07-2017 SMD11_RS20170 d0a917c0aeab4aa909530f62acd2109b 325 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 06-07-2017 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 SMD11_RS20170 d0a917c0aeab4aa909530f62acd2109b 325 Pfam PF14572 Phosphoribosyl synthetase-associated domain 215 321 3.8E-24 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SMD11_RS20170 d0a917c0aeab4aa909530f62acd2109b 325 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 322 46.829 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SMD11_RS20170 d0a917c0aeab4aa909530f62acd2109b 325 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 2.5E-44 T 06-07-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SMD11_RS20170 d0a917c0aeab4aa909530f62acd2109b 325 SUPERFAMILY SSF53271 77 313 4.64E-63 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS20170 d0a917c0aeab4aa909530f62acd2109b 325 Gene3D G3DSA:3.40.50.2020 168 293 6.6E-47 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS20170 d0a917c0aeab4aa909530f62acd2109b 325 Gene3D G3DSA:3.40.50.2020 7 167 2.7E-69 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS20170 d0a917c0aeab4aa909530f62acd2109b 325 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 322 1.3E-113 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SMD11_RS23870 d1c479ee48d871260f0e9900cad08437 1033 SUPERFAMILY SSF81593 880 1031 8.63E-36 T 06-07-2017 SMD11_RS23870 d1c479ee48d871260f0e9900cad08437 1033 SUPERFAMILY SSF81301 717 874 2.84E-57 T 06-07-2017 SMD11_RS23870 d1c479ee48d871260f0e9900cad08437 1033 SUPERFAMILY SSF81301 569 681 2.84E-57 T 06-07-2017 SMD11_RS23870 d1c479ee48d871260f0e9900cad08437 1033 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 713 865 5.2E-35 T 06-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 SMD11_RS23870 d1c479ee48d871260f0e9900cad08437 1033 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 89 323 2.5E-50 T 06-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 SMD11_RS23870 d1c479ee48d871260f0e9900cad08437 1033 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 597 677 1.1E-4 T 06-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 SMD11_RS23870 d1c479ee48d871260f0e9900cad08437 1033 Gene3D G3DSA:3.30.460.10 173 333 7.0E-57 T 06-07-2017 SMD11_RS23870 d1c479ee48d871260f0e9900cad08437 1033 Gene3D G3DSA:3.30.460.10 715 874 1.9E-49 T 06-07-2017 SMD11_RS23870 d1c479ee48d871260f0e9900cad08437 1033 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 85 1021 17.026 T 06-07-2017 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 SMD11_RS23870 d1c479ee48d871260f0e9900cad08437 1033 SUPERFAMILY SSF81301 71 332 3.04E-67 T 06-07-2017 SMD11_RS23870 d1c479ee48d871260f0e9900cad08437 1033 SUPERFAMILY SSF81593 338 493 7.85E-37 T 06-07-2017 SMD11_RS23870 d1c479ee48d871260f0e9900cad08437 1033 Pfam PF08335 GlnD PII-uridylyltransferase 888 1030 6.3E-20 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 SMD11_RS23870 d1c479ee48d871260f0e9900cad08437 1033 Pfam PF08335 GlnD PII-uridylyltransferase 356 492 2.5E-34 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 SMD11_RS16040 1942e6b8cfe5ec0d56c1442ccadc165a 649 Gene3D G3DSA:1.10.10.60 575 606 7.1E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS16040 1942e6b8cfe5ec0d56c1442ccadc165a 649 Pfam PF13185 GAF domain 88 227 2.3E-9 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS16040 1942e6b8cfe5ec0d56c1442ccadc165a 649 SUPERFAMILY SSF55781 69 234 5.45E-18 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS16040 1942e6b8cfe5ec0d56c1442ccadc165a 649 Pfam PF13556 PucR C-terminal helix-turn-helix domain 573 629 4.3E-20 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain SMD11_RS16040 1942e6b8cfe5ec0d56c1442ccadc165a 649 Gene3D G3DSA:3.30.450.40 65 236 1.2E-21 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS16040 1942e6b8cfe5ec0d56c1442ccadc165a 649 SMART SM00065 90 237 5.3E-13 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS23185 3c3096763fc893de9b87155f429dc8d0 420 Gene3D G3DSA:3.40.47.10 10 266 3.8E-68 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS23185 3c3096763fc893de9b87155f429dc8d0 420 PIRSF PIRSF000447 3 420 4.7E-142 T 06-07-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 SMD11_RS23185 3c3096763fc893de9b87155f429dc8d0 420 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 6 418 2.5E-149 T 06-07-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 SMD11_RS23185 3c3096763fc893de9b87155f429dc8d0 420 SUPERFAMILY SSF53901 221 419 8.76E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS23185 3c3096763fc893de9b87155f429dc8d0 420 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 253 4.4E-54 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS23185 3c3096763fc893de9b87155f429dc8d0 420 SUPERFAMILY SSF53901 6 258 4.26E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS23185 3c3096763fc893de9b87155f429dc8d0 420 SMART SM00825 Beta-ketoacyl synthase 8 411 2.3E-13 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS23185 3c3096763fc893de9b87155f429dc8d0 420 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 375 1.4E-31 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS23185 3c3096763fc893de9b87155f429dc8d0 420 Gene3D G3DSA:3.40.47.10 270 419 3.5E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS03410 a7dc881c978c08a5c280d607222d3331 220 Pfam PF13649 Methyltransferase domain 56 144 4.6E-16 T 06-07-2017 SMD11_RS03410 a7dc881c978c08a5c280d607222d3331 220 SUPERFAMILY SSF53335 11 214 1.13E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS03410 a7dc881c978c08a5c280d607222d3331 220 Gene3D G3DSA:3.40.50.150 10 215 1.3E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS03540 7fe4e50372955d370edfed34d5392522 230 SUPERFAMILY SSF100950 52 223 2.55E-40 T 06-07-2017 SMD11_RS03540 7fe4e50372955d370edfed34d5392522 230 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 124 223 3.1E-21 T 06-07-2017 IPR003741 LUD domain SMD11_RS03540 7fe4e50372955d370edfed34d5392522 230 Gene3D G3DSA:3.40.50.10420 51 223 1.9E-56 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain SMD11_RS32835 7e50d595c0f9a058695d47e320d63ecc 342 Gene3D G3DSA:3.40.50.720 171 286 1.2E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32835 7e50d595c0f9a058695d47e320d63ecc 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD11_RS32835 7e50d595c0f9a058695d47e320d63ecc 342 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 3 340 6.0E-139 T 06-07-2017 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 SMD11_RS32835 7e50d595c0f9a058695d47e320d63ecc 342 Pfam PF00107 Zinc-binding dehydrogenase 174 299 6.9E-25 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS32835 7e50d595c0f9a058695d47e320d63ecc 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 133 3.6E-31 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS32835 7e50d595c0f9a058695d47e320d63ecc 342 Gene3D G3DSA:3.90.180.10 1 170 1.7E-48 T 06-07-2017 IPR011032 GroES-like SMD11_RS32835 7e50d595c0f9a058695d47e320d63ecc 342 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 1 340 57.031 T 06-07-2017 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 SMD11_RS32835 7e50d595c0f9a058695d47e320d63ecc 342 SUPERFAMILY SSF50129 1 173 2.13E-52 T 06-07-2017 IPR011032 GroES-like SMD11_RS32835 7e50d595c0f9a058695d47e320d63ecc 342 SUPERFAMILY SSF51735 142 298 3.05E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS23015 cfe5df0de3816f8bf7dcc83ba3b0ac31 441 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 11 433 30.62 T 06-07-2017 IPR023023 Deoxyguanosinetriphosphate triphosphohydrolase, type 2 SMD11_RS23015 cfe5df0de3816f8bf7dcc83ba3b0ac31 441 SUPERFAMILY SSF109604 29 182 3.67E-56 T 06-07-2017 SMD11_RS23015 cfe5df0de3816f8bf7dcc83ba3b0ac31 441 SUPERFAMILY SSF109604 213 386 3.67E-56 T 06-07-2017 SMD11_RS23015 cfe5df0de3816f8bf7dcc83ba3b0ac31 441 Gene3D G3DSA:1.10.3410.10 229 360 2.7E-20 T 06-07-2017 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain SMD11_RS23015 cfe5df0de3816f8bf7dcc83ba3b0ac31 441 SMART SM00471 73 242 7.8E-14 T 06-07-2017 IPR003607 HD/PDEase domain SMD11_RS23015 cfe5df0de3816f8bf7dcc83ba3b0ac31 441 Pfam PF01966 HD domain 77 231 2.9E-16 T 06-07-2017 IPR006674 HD domain SMD11_RS23015 cfe5df0de3816f8bf7dcc83ba3b0ac31 441 Gene3D G3DSA:1.10.3210.10 23 228 5.4E-64 T 06-07-2017 IPR006674 HD domain SMD11_RS23015 cfe5df0de3816f8bf7dcc83ba3b0ac31 441 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 35 432 5.7E-72 T 06-07-2017 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 SMD11_RS23015 cfe5df0de3816f8bf7dcc83ba3b0ac31 441 Pfam PF13286 Phosphohydrolase-associated domain 340 428 5.3E-17 T 06-07-2017 IPR026875 Phosphohydrolase-associated domain SMD11_RS21880 ff8ed225ab2051563e01aef1eb048db2 333 SUPERFAMILY SSF51735 2 148 2.27E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS21880 ff8ed225ab2051563e01aef1eb048db2 333 SUPERFAMILY SSF55347 127 292 4.69E-26 T 06-07-2017 SMD11_RS21880 ff8ed225ab2051563e01aef1eb048db2 333 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 131 229 1.2E-9 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD11_RS21880 ff8ed225ab2051563e01aef1eb048db2 333 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 119 1.3E-22 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD11_RS21880 ff8ed225ab2051563e01aef1eb048db2 333 Gene3D G3DSA:3.40.50.720 1 131 4.7E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS21880 ff8ed225ab2051563e01aef1eb048db2 333 Gene3D G3DSA:3.30.360.10 132 330 2.2E-52 T 06-07-2017 SMD11_RS29395 23464ff985602443a2f780deb3a408b5 494 SUPERFAMILY SSF103473 16 211 4.27E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS29395 23464ff985602443a2f780deb3a408b5 494 SUPERFAMILY SSF103473 265 474 4.27E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS29395 23464ff985602443a2f780deb3a408b5 494 Gene3D G3DSA:1.20.1250.20 22 208 1.5E-34 T 06-07-2017 SMD11_RS29395 23464ff985602443a2f780deb3a408b5 494 Gene3D G3DSA:1.20.1250.20 279 471 1.2E-13 T 06-07-2017 SMD11_RS29395 23464ff985602443a2f780deb3a408b5 494 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 1.5E-5 T 06-07-2017 SMD11_RS29395 23464ff985602443a2f780deb3a408b5 494 PRINTS PR01036 Tetracycline resistance protein TetB signature 420 439 1.5E-5 T 06-07-2017 SMD11_RS29395 23464ff985602443a2f780deb3a408b5 494 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 1.5E-5 T 06-07-2017 SMD11_RS29395 23464ff985602443a2f780deb3a408b5 494 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 1.5E-5 T 06-07-2017 SMD11_RS29395 23464ff985602443a2f780deb3a408b5 494 Pfam PF07690 Major Facilitator Superfamily 29 429 1.5E-45 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS24665 49cafbd1b3dcef8b20ae4186cb53a69e 245 SUPERFAMILY SSF88697 5 219 5.96E-38 T 06-07-2017 IPR015947 PUA-like domain SMD11_RS24665 49cafbd1b3dcef8b20ae4186cb53a69e 245 SMART SM00464 5 221 1.7E-38 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 SMD11_RS24665 49cafbd1b3dcef8b20ae4186cb53a69e 245 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 6 219 1.3E-27 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 SMD11_RS16565 fdb400d26f9ded1b28650314ac50f998 359 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 8 357 49.03 T 06-07-2017 IPR024892 Putative phenylalanine aminotransferase SMD11_RS16565 fdb400d26f9ded1b28650314ac50f998 359 Pfam PF00155 Aminotransferase class I and II 33 330 1.4E-52 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS16565 fdb400d26f9ded1b28650314ac50f998 359 SUPERFAMILY SSF53383 26 350 5.17E-78 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS16565 fdb400d26f9ded1b28650314ac50f998 359 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 220 229 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMD11_RS16565 fdb400d26f9ded1b28650314ac50f998 359 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 7 356 49.646 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SMD11_RS16565 fdb400d26f9ded1b28650314ac50f998 359 Gene3D G3DSA:3.40.640.10 45 262 2.4E-65 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS16565 fdb400d26f9ded1b28650314ac50f998 359 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 353 3.3E-87 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 SMD11_RS16565 fdb400d26f9ded1b28650314ac50f998 359 Gene3D G3DSA:3.90.1150.10 263 355 4.8E-11 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS18540 bd514f101486d5cdfc25edf649427513 184 Gene3D G3DSA:3.40.50.700 24 149 7.6E-34 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18540 bd514f101486d5cdfc25edf649427513 184 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.191 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18540 bd514f101486d5cdfc25edf649427513 184 SUPERFAMILY SSF56770 9 154 1.7E-65 T 06-07-2017 SMD11_RS18540 bd514f101486d5cdfc25edf649427513 184 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18540 bd514f101486d5cdfc25edf649427513 184 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 1.2E-69 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18540 bd514f101486d5cdfc25edf649427513 184 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 1.1E-24 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS01480 8425e944b379d3e34073e75897ad04bf 376 SUPERFAMILY SSF55909 21 376 9.28E-107 T 06-07-2017 SMD11_RS01480 8425e944b379d3e34073e75897ad04bf 376 Gene3D G3DSA:3.75.10.10 21 375 4.3E-138 T 06-07-2017 SMD11_RS27470 5c22ee2aecfbf963aefdbe03719bee1c 275 Pfam PF01522 Polysaccharide deacetylase 50 171 1.8E-28 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS27470 5c22ee2aecfbf963aefdbe03719bee1c 275 Gene3D G3DSA:3.20.20.370 33 246 7.6E-45 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS27470 5c22ee2aecfbf963aefdbe03719bee1c 275 SUPERFAMILY SSF88713 46 245 1.67E-44 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS06685 4640a55a4e44268964b71080c041b84b 529 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 326 509 1.0E-12 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMD11_RS06685 4640a55a4e44268964b71080c041b84b 529 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 58 295 2.4E-30 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SMD11_RS06685 4640a55a4e44268964b71080c041b84b 529 SMART SM00939 314 524 1.3E-19 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SMD11_RS06685 4640a55a4e44268964b71080c041b84b 529 SUPERFAMILY SSF49785 404 527 6.59E-15 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS06685 4640a55a4e44268964b71080c041b84b 529 Gene3D G3DSA:3.40.50.1820 242 345 5.6E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS06685 4640a55a4e44268964b71080c041b84b 529 Gene3D G3DSA:3.40.50.1820 26 190 5.6E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS06685 4640a55a4e44268964b71080c041b84b 529 Gene3D G3DSA:2.60.120.260 346 527 9.1E-13 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS06685 4640a55a4e44268964b71080c041b84b 529 SUPERFAMILY SSF53474 49 350 3.8E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28880 554c90b53878eed0037f6a5a20faf935 195 Pfam PF01327 Polypeptide deformylase 16 163 6.4E-44 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS28880 554c90b53878eed0037f6a5a20faf935 195 Hamap MF_00163 Peptide deformylase [def]. 12 175 27.766 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS28880 554c90b53878eed0037f6a5a20faf935 195 Gene3D G3DSA:3.90.45.10 15 174 3.2E-58 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS28880 554c90b53878eed0037f6a5a20faf935 195 PRINTS PR01576 Peptide deformylase signature 133 162 6.6E-33 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS28880 554c90b53878eed0037f6a5a20faf935 195 PRINTS PR01576 Peptide deformylase signature 43 72 6.6E-33 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS28880 554c90b53878eed0037f6a5a20faf935 195 PRINTS PR01576 Peptide deformylase signature 114 132 6.6E-33 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS28880 554c90b53878eed0037f6a5a20faf935 195 PRINTS PR01576 Peptide deformylase signature 102 113 6.6E-33 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS28880 554c90b53878eed0037f6a5a20faf935 195 SUPERFAMILY SSF56420 13 170 1.57E-53 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS28880 554c90b53878eed0037f6a5a20faf935 195 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 20 167 4.5E-40 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS14955 9b060b6b211573627449fc07c03cf67d 664 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 339 9.3E-45 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS14955 9b060b6b211573627449fc07c03cf67d 664 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 120 610 6.2E-233 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 SMD11_RS14955 9b060b6b211573627449fc07c03cf67d 664 Pfam PF01434 Peptidase family M41 402 609 1.8E-80 T 06-07-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 SMD11_RS14955 9b060b6b211573627449fc07c03cf67d 664 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 619 37.364 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 SMD11_RS14955 9b060b6b211573627449fc07c03cf67d 664 SMART SM00382 203 342 6.2E-25 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS14955 9b060b6b211573627449fc07c03cf67d 664 SUPERFAMILY SSF52540 161 411 1.95E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14955 9b060b6b211573627449fc07c03cf67d 664 Gene3D G3DSA:1.10.8.60 348 414 4.1E-24 T 06-07-2017 SMD11_RS14955 9b060b6b211573627449fc07c03cf67d 664 Gene3D G3DSA:3.40.50.300 163 347 6.9E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14955 9b060b6b211573627449fc07c03cf67d 664 SUPERFAMILY SSF140990 421 616 1.02E-73 T 06-07-2017 SMD11_RS14955 9b060b6b211573627449fc07c03cf67d 664 ProSitePatterns PS00674 AAA-protein family signature. 310 328 - T 06-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 SMD11_RS18195 c8dce0e3589cb7fec42fd787d5ee1953 332 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS18195 c8dce0e3589cb7fec42fd787d5ee1953 332 SUPERFAMILY SSF52374 2 328 6.57E-80 T 06-07-2017 SMD11_RS18195 c8dce0e3589cb7fec42fd787d5ee1953 332 Gene3D G3DSA:1.10.240.10 217 317 8.6E-12 T 06-07-2017 SMD11_RS18195 c8dce0e3589cb7fec42fd787d5ee1953 332 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 329 36.818 T 06-07-2017 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 SMD11_RS18195 c8dce0e3589cb7fec42fd787d5ee1953 332 Pfam PF00579 tRNA synthetases class I (W and Y) 3 283 3.8E-69 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS18195 c8dce0e3589cb7fec42fd787d5ee1953 332 Gene3D G3DSA:3.40.50.620 2 216 5.3E-81 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS18195 c8dce0e3589cb7fec42fd787d5ee1953 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 65 84 3.3E-21 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMD11_RS18195 c8dce0e3589cb7fec42fd787d5ee1953 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 197 207 3.3E-21 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMD11_RS18195 c8dce0e3589cb7fec42fd787d5ee1953 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 144 165 3.3E-21 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMD11_RS18195 c8dce0e3589cb7fec42fd787d5ee1953 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 3.3E-21 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMD11_RS18195 c8dce0e3589cb7fec42fd787d5ee1953 332 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 328 8.1E-94 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SMD11_RS27925 ae4d59f8d87178b21d42e0b64f6fd700 555 Gene3D G3DSA:3.40.50.1820 48 553 9.8E-136 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS27925 ae4d59f8d87178b21d42e0b64f6fd700 555 SUPERFAMILY SSF53474 50 527 9.63E-113 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS27925 ae4d59f8d87178b21d42e0b64f6fd700 555 Pfam PF00135 Carboxylesterase family 51 520 6.6E-105 T 06-07-2017 IPR002018 Carboxylesterase, type B SMD11_RS27925 ae4d59f8d87178b21d42e0b64f6fd700 555 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 221 236 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site SMD11_RS30090 d35240af3282531d80b9b7ffdab8feaf 275 SUPERFAMILY SSF48452 120 266 7.4E-32 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS30090 d35240af3282531d80b9b7ffdab8feaf 275 Gene3D G3DSA:1.10.10.10 11 96 8.4E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30090 d35240af3282531d80b9b7ffdab8feaf 275 Pfam PF03704 Bacterial transcriptional activator domain 102 246 2.7E-39 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS30090 d35240af3282531d80b9b7ffdab8feaf 275 SMART SM00862 16 95 4.2E-11 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS30090 d35240af3282531d80b9b7ffdab8feaf 275 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 95 9.9E-12 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS30090 d35240af3282531d80b9b7ffdab8feaf 275 SMART SM01043 102 246 1.4E-43 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS30090 d35240af3282531d80b9b7ffdab8feaf 275 SUPERFAMILY SSF46894 6 95 2.58E-13 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS19460 a73eb6e7b103af64e0ae55bf17cf5e3b 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 254 7.7E-66 T 06-07-2017 SMD11_RS19460 a73eb6e7b103af64e0ae55bf17cf5e3b 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.2E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19460 a73eb6e7b103af64e0ae55bf17cf5e3b 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.2E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19460 a73eb6e7b103af64e0ae55bf17cf5e3b 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.2E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19460 a73eb6e7b103af64e0ae55bf17cf5e3b 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19460 a73eb6e7b103af64e0ae55bf17cf5e3b 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.2E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19460 a73eb6e7b103af64e0ae55bf17cf5e3b 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.2E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19460 a73eb6e7b103af64e0ae55bf17cf5e3b 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS19460 a73eb6e7b103af64e0ae55bf17cf5e3b 262 SUPERFAMILY SSF51735 6 256 1.73E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19460 a73eb6e7b103af64e0ae55bf17cf5e3b 262 Gene3D G3DSA:3.40.50.720 3 256 2.1E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19460 a73eb6e7b103af64e0ae55bf17cf5e3b 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19460 a73eb6e7b103af64e0ae55bf17cf5e3b 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 4.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19460 a73eb6e7b103af64e0ae55bf17cf5e3b 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 4.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS18185 307eea8cf7c593eae7eb568724339956 517 Pfam PF00916 Sulfate permease family 37 404 4.7E-58 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 SMD11_RS29940 9b6681d06ef0f8dd8955e1ada1160f12 192 SUPERFAMILY SSF49329 64 189 4.32E-15 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD11_RS29940 9b6681d06ef0f8dd8955e1ada1160f12 192 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 64 188 2.5E-10 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD11_RS29940 9b6681d06ef0f8dd8955e1ada1160f12 192 Gene3D G3DSA:2.60.40.200 65 187 9.4E-12 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 SMD11_RS17715 f9650eacca5301ebeee88f1baa113b19 207 Gene3D G3DSA:1.10.472.60 69 173 5.6E-29 T 06-07-2017 IPR023169 UPF0413, central domain SMD11_RS17715 f9650eacca5301ebeee88f1baa113b19 207 SUPERFAMILY SSF52833 4 206 1.12E-29 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS17715 f9650eacca5301ebeee88f1baa113b19 207 Pfam PF01323 DSBA-like thioredoxin domain 10 181 1.9E-9 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMD11_RS17715 f9650eacca5301ebeee88f1baa113b19 207 Gene3D G3DSA:3.40.30.10 2 68 9.9E-20 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS07045 8bb9a3441ccaebda4099d85ceead07fd 272 Pfam PF13437 HlyD family secretion protein 107 194 1.8E-6 T 06-07-2017 SMD11_RS07045 8bb9a3441ccaebda4099d85ceead07fd 272 Gene3D G3DSA:2.40.50.100 66 136 3.6E-8 T 06-07-2017 SMD11_RS07045 8bb9a3441ccaebda4099d85ceead07fd 272 SUPERFAMILY SSF51230 62 135 7.0E-8 T 06-07-2017 IPR011053 Single hybrid motif SMD11_RS25545 772a76b119180dd9da2c6be048989743 92 Pfam PF04226 Transglycosylase associated protein 33 78 1.8E-8 T 06-07-2017 IPR007341 Transglycosylase-associated protein GO:0016021 SMD11_RS02315 1357ef7ff72e4e70748bae04b007d784 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 2.9E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS02315 1357ef7ff72e4e70748bae04b007d784 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 2.9E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS02315 1357ef7ff72e4e70748bae04b007d784 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 2.9E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS02315 1357ef7ff72e4e70748bae04b007d784 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 2.9E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS02315 1357ef7ff72e4e70748bae04b007d784 262 Gene3D G3DSA:3.40.50.1820 3 258 2.3E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS02315 1357ef7ff72e4e70748bae04b007d784 262 Pfam PF00561 alpha/beta hydrolase fold 23 242 4.3E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS02315 1357ef7ff72e4e70748bae04b007d784 262 SUPERFAMILY SSF53474 6 257 8.51E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01120 d495693988b7c6bb35e15b6a85070bbd 198 SMART SM00947 26 189 1.5E-60 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS01120 d495693988b7c6bb35e15b6a85070bbd 198 Gene3D G3DSA:3.40.1050.10 1 192 3.9E-59 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS01120 d495693988b7c6bb35e15b6a85070bbd 198 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 38 45 - T 06-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS01120 d495693988b7c6bb35e15b6a85070bbd 198 SUPERFAMILY SSF53056 9 191 1.16E-53 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS01120 d495693988b7c6bb35e15b6a85070bbd 198 Pfam PF00484 Carbonic anhydrase 33 185 2.7E-44 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS01120 d495693988b7c6bb35e15b6a85070bbd 198 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 06-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS23865 3caacd4d243e8d4e4715f58a7840935f 453 Pfam PF00120 Glutamine synthetase, catalytic domain 105 448 1.4E-126 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS23865 3caacd4d243e8d4e4715f58a7840935f 453 SUPERFAMILY SSF55931 106 450 9.32E-114 T 06-07-2017 SMD11_RS23865 3caacd4d243e8d4e4715f58a7840935f 453 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 449 5.2E-132 T 06-07-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS23865 3caacd4d243e8d4e4715f58a7840935f 453 Gene3D G3DSA:3.10.20.70 6 107 6.2E-39 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS23865 3caacd4d243e8d4e4715f58a7840935f 453 Gene3D G3DSA:3.30.590.10 108 440 1.7E-112 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SMD11_RS23865 3caacd4d243e8d4e4715f58a7840935f 453 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 98 1.3E-28 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS23865 3caacd4d243e8d4e4715f58a7840935f 453 SMART SM01230 104 363 7.5E-124 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS23865 3caacd4d243e8d4e4715f58a7840935f 453 SUPERFAMILY SSF54368 8 104 1.44E-30 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS23865 3caacd4d243e8d4e4715f58a7840935f 453 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 232 247 - T 06-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 SMD11_RS00105 6b53b83c7cbbe443b8bc1ad4b814b8fb 69 Gene3D G3DSA:3.40.50.150 1 67 2.0E-6 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS00035 f8ab31754fd81790e9a59da396b3929a 253 SUPERFAMILY SSF51735 6 245 6.32E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00035 f8ab31754fd81790e9a59da396b3929a 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 184 0.0015 T 06-07-2017 SMD11_RS00035 f8ab31754fd81790e9a59da396b3929a 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS00035 f8ab31754fd81790e9a59da396b3929a 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 8.2E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00035 f8ab31754fd81790e9a59da396b3929a 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 8.2E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00035 f8ab31754fd81790e9a59da396b3929a 253 Gene3D G3DSA:3.40.50.720 1 246 4.1E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00035 f8ab31754fd81790e9a59da396b3929a 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.2E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00035 f8ab31754fd81790e9a59da396b3929a 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.2E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00035 f8ab31754fd81790e9a59da396b3929a 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 2.2E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00035 f8ab31754fd81790e9a59da396b3929a 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.2E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00035 f8ab31754fd81790e9a59da396b3929a 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.2E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00035 f8ab31754fd81790e9a59da396b3929a 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 245 1.4E-62 T 06-07-2017 SMD11_RS00450 4f561a7abaae8c606bb99e3aa4db14f0 156 SUPERFAMILY SSF47413 5 85 6.44E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS00450 4f561a7abaae8c606bb99e3aa4db14f0 156 Pfam PF02560 Cyanate lyase C-terminal domain 88 154 4.3E-32 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS00450 4f561a7abaae8c606bb99e3aa4db14f0 156 PRINTS PR01693 Cyanase signature 91 105 3.9E-32 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS00450 4f561a7abaae8c606bb99e3aa4db14f0 156 PRINTS PR01693 Cyanase signature 141 151 3.9E-32 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS00450 4f561a7abaae8c606bb99e3aa4db14f0 156 PRINTS PR01693 Cyanase signature 109 125 3.9E-32 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS00450 4f561a7abaae8c606bb99e3aa4db14f0 156 PRINTS PR01693 Cyanase signature 22 37 3.9E-32 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS00450 4f561a7abaae8c606bb99e3aa4db14f0 156 PRINTS PR01693 Cyanase signature 42 59 3.9E-32 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS00450 4f561a7abaae8c606bb99e3aa4db14f0 156 Hamap MF_00535 Cyanate hydratase [cynS]. 1 156 78.073 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS00450 4f561a7abaae8c606bb99e3aa4db14f0 156 TIGRFAM TIGR00673 cynS: cyanase 12 156 3.4E-59 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS00450 4f561a7abaae8c606bb99e3aa4db14f0 156 PIRSF PIRSF001263 3 156 9.0E-62 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS00450 4f561a7abaae8c606bb99e3aa4db14f0 156 Gene3D G3DSA:1.10.260.40 1 86 2.0E-30 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS00450 4f561a7abaae8c606bb99e3aa4db14f0 156 SUPERFAMILY SSF55234 88 155 2.22E-29 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS00450 4f561a7abaae8c606bb99e3aa4db14f0 156 Gene3D G3DSA:3.30.1160.10 89 156 3.1E-36 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS00450 4f561a7abaae8c606bb99e3aa4db14f0 156 SMART SM01116 83 156 8.2E-47 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS14045 88cb86dc67349f4bd9865d512024d849 199 Pfam PF03928 Haem-degrading 73 195 9.1E-29 T 06-07-2017 IPR005624 Haem-degrading SMD11_RS14045 88cb86dc67349f4bd9865d512024d849 199 SUPERFAMILY SSF143744 67 198 1.57E-32 T 06-07-2017 SMD11_RS20495 d05247297ee1b864df38f4b35896076f 474 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 56 294 1.0E-36 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMD11_RS20495 d05247297ee1b864df38f4b35896076f 474 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 350 407 9.8E-7 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMD11_RS20495 d05247297ee1b864df38f4b35896076f 474 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 235 251 - T 06-07-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site SMD11_RS20495 d05247297ee1b864df38f4b35896076f 474 PRINTS PR01181 Diaminopimelate decarboxylase signature 399 421 2.2E-5 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS20495 d05247297ee1b864df38f4b35896076f 474 PRINTS PR01181 Diaminopimelate decarboxylase signature 83 100 2.2E-5 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS20495 d05247297ee1b864df38f4b35896076f 474 PRINTS PR01181 Diaminopimelate decarboxylase signature 171 180 2.2E-5 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS20495 d05247297ee1b864df38f4b35896076f 474 SUPERFAMILY SSF51419 37 297 2.47E-51 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS20495 d05247297ee1b864df38f4b35896076f 474 SUPERFAMILY SSF50621 271 412 4.6E-30 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS20495 d05247297ee1b864df38f4b35896076f 474 Gene3D G3DSA:2.40.37.10 281 411 2.1E-32 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS20495 d05247297ee1b864df38f4b35896076f 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 85 97 1.5E-11 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS20495 d05247297ee1b864df38f4b35896076f 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 389 402 1.5E-11 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS20495 d05247297ee1b864df38f4b35896076f 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 65 83 1.5E-11 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS20495 d05247297ee1b864df38f4b35896076f 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 198 211 1.5E-11 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS20495 d05247297ee1b864df38f4b35896076f 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 284 303 1.5E-11 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS20495 d05247297ee1b864df38f4b35896076f 474 Gene3D G3DSA:3.20.20.10 40 280 1.8E-58 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS20595 1c15b44cf3f94df77150c266e426a21c 126 SUPERFAMILY SSF54593 6 123 4.54E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS20595 1c15b44cf3f94df77150c266e426a21c 126 Gene3D G3DSA:3.10.180.10 5 123 1.5E-13 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS27535 db03d42b63cb5736c733328833c70e2a 456 SMART SM01091 361 438 5.2E-17 T 06-07-2017 IPR005170 Transporter-associated domain SMD11_RS27535 db03d42b63cb5736c733328833c70e2a 456 Pfam PF00571 CBS domain 222 272 0.0059 T 06-07-2017 IPR000644 CBS domain SMD11_RS27535 db03d42b63cb5736c733328833c70e2a 456 Pfam PF00571 CBS domain 298 339 7.3E-4 T 06-07-2017 IPR000644 CBS domain SMD11_RS27535 db03d42b63cb5736c733328833c70e2a 456 Pfam PF03471 Transporter associated domain 366 436 2.7E-15 T 06-07-2017 IPR005170 Transporter-associated domain SMD11_RS27535 db03d42b63cb5736c733328833c70e2a 456 SUPERFAMILY SSF56176 365 437 8.72E-15 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS27535 db03d42b63cb5736c733328833c70e2a 456 SUPERFAMILY SSF54631 218 350 3.03E-23 T 06-07-2017 SMD11_RS27535 db03d42b63cb5736c733328833c70e2a 456 Pfam PF01595 Domain of unknown function DUF21 12 204 3.3E-35 T 06-07-2017 IPR002550 Domain of unknown function DUF21 SMD11_RS27535 db03d42b63cb5736c733328833c70e2a 456 Gene3D G3DSA:3.10.580.10 212 333 6.8E-17 T 06-07-2017 SMD11_RS27535 db03d42b63cb5736c733328833c70e2a 456 Gene3D G3DSA:3.30.465.10 334 436 9.1E-23 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS14960 89ec5f0aae90699c31e7cc73f7121e57 179 Pfam PF00156 Phosphoribosyl transferase domain 14 159 4.4E-25 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMD11_RS14960 89ec5f0aae90699c31e7cc73f7121e57 179 SUPERFAMILY SSF53271 4 177 1.14E-54 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS14960 89ec5f0aae90699c31e7cc73f7121e57 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 172 6.7E-65 T 06-07-2017 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 SMD11_RS14960 89ec5f0aae90699c31e7cc73f7121e57 179 Gene3D G3DSA:3.40.50.2020 3 177 7.7E-80 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS26515 e7ee664da116eaff47d9c2047e8edbf1 72 Pfam PF05639 Pup-like protein 4 72 5.5E-30 T 06-07-2017 IPR008515 Ubiquitin-like, Pup SMD11_RS26515 e7ee664da116eaff47d9c2047e8edbf1 72 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 41 72 4.6E-21 T 06-07-2017 IPR008515 Ubiquitin-like, Pup SMD11_RS26515 e7ee664da116eaff47d9c2047e8edbf1 72 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 72 17.726 T 06-07-2017 IPR008515 Ubiquitin-like, Pup SMD11_RS01430 7e9a24364ae3f912495980885b79d4ef 409 PIRSF PIRSF016578 12 408 4.5E-118 T 06-07-2017 SMD11_RS01430 7e9a24364ae3f912495980885b79d4ef 409 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 254 385 4.0E-22 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain SMD11_RS01430 7e9a24364ae3f912495980885b79d4ef 409 Gene3D G3DSA:1.20.140.10 217 402 2.6E-39 T 06-07-2017 SMD11_RS01430 7e9a24364ae3f912495980885b79d4ef 409 Gene3D G3DSA:2.40.110.10 131 216 9.5E-25 T 06-07-2017 SMD11_RS01430 7e9a24364ae3f912495980885b79d4ef 409 SUPERFAMILY SSF47203 252 400 7.8E-9 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS01430 7e9a24364ae3f912495980885b79d4ef 409 SUPERFAMILY SSF56645 30 222 2.36E-31 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS01430 7e9a24364ae3f912495980885b79d4ef 409 Gene3D G3DSA:1.10.540.10 16 128 1.6E-40 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS01430 7e9a24364ae3f912495980885b79d4ef 409 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 36 107 6.8E-8 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS26485 631cb586728547289bb1c34bc9a171a6 301 Gene3D G3DSA:3.40.50.150 77 282 3.0E-65 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS26485 631cb586728547289bb1c34bc9a171a6 301 Gene3D G3DSA:3.10.330.20 2 75 5.2E-33 T 06-07-2017 SMD11_RS26485 631cb586728547289bb1c34bc9a171a6 301 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 80 244 3.1E-22 T 06-07-2017 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 SMD11_RS26485 631cb586728547289bb1c34bc9a171a6 301 SUPERFAMILY SSF53335 13 266 9.41E-72 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS26485 631cb586728547289bb1c34bc9a171a6 301 PIRSF PIRSF017269 8 276 6.5E-86 T 06-07-2017 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 SMD11_RS26485 631cb586728547289bb1c34bc9a171a6 301 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 11 61 5.7E-29 T 06-07-2017 SMD11_RS04610 00e797e1039df1c47efe1d304eac0591 293 Pfam PF12146 Serine aminopeptidase, S33 77 205 5.3E-12 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 SMD11_RS04610 00e797e1039df1c47efe1d304eac0591 293 SUPERFAMILY SSF53474 77 273 8.33E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04610 00e797e1039df1c47efe1d304eac0591 293 Gene3D G3DSA:3.40.50.1820 62 284 1.7E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04220 fba98f9ccca5c9586b5feebff25451c9 407 SUPERFAMILY SSF54373 170 291 3.73E-23 T 06-07-2017 SMD11_RS04220 fba98f9ccca5c9586b5feebff25451c9 407 Pfam PF01494 FAD binding domain 294 358 4.8E-6 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS04220 fba98f9ccca5c9586b5feebff25451c9 407 Gene3D G3DSA:3.50.50.60 5 62 9.0E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS04220 fba98f9ccca5c9586b5feebff25451c9 407 Gene3D G3DSA:3.50.50.60 286 364 9.0E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS04220 fba98f9ccca5c9586b5feebff25451c9 407 Gene3D G3DSA:3.50.50.60 94 172 9.0E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS04220 fba98f9ccca5c9586b5feebff25451c9 407 SUPERFAMILY SSF51905 293 378 3.46E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS04220 fba98f9ccca5c9586b5feebff25451c9 407 SUPERFAMILY SSF51905 4 166 3.46E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS04220 fba98f9ccca5c9586b5feebff25451c9 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 8.8E-17 T 06-07-2017 SMD11_RS04220 fba98f9ccca5c9586b5feebff25451c9 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 313 8.8E-17 T 06-07-2017 SMD11_RS04220 fba98f9ccca5c9586b5feebff25451c9 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 8.8E-17 T 06-07-2017 SMD11_RS04220 fba98f9ccca5c9586b5feebff25451c9 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 313 329 8.8E-17 T 06-07-2017 SMD11_RS13675 3a84b101fa9795d72b6cb7eed291ae41 395 Pfam PF01474 Class-II DAHP synthetase family 183 390 4.1E-74 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMD11_RS13675 3a84b101fa9795d72b6cb7eed291ae41 395 Pfam PF01474 Class-II DAHP synthetase family 13 177 2.0E-47 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMD11_RS13675 3a84b101fa9795d72b6cb7eed291ae41 395 SUPERFAMILY SSF51569 13 392 7.32E-130 T 06-07-2017 SMD11_RS10630 d9fb0bf1f557b107dfdfa3b5f60e2e0d 212 SUPERFAMILY SSF51219 4 206 3.92E-45 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMD11_RS10630 d9fb0bf1f557b107dfdfa3b5f60e2e0d 212 Gene3D G3DSA:3.60.160.10 9 207 2.8E-42 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 SMD11_RS10630 d9fb0bf1f557b107dfdfa3b5f60e2e0d 212 Pfam PF01987 Mitochondrial biogenesis AIM24 5 202 3.5E-34 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 SMD11_RS03030 d2f48734b34bf4a6b4e4a0c4fb97b565 69 SUPERFAMILY SSF160582 4 67 4.18E-29 T 06-07-2017 SMD11_RS03030 d2f48734b34bf4a6b4e4a0c4fb97b565 69 Gene3D G3DSA:3.90.820.10 13 67 9.2E-29 T 06-07-2017 SMD11_RS03030 d2f48734b34bf4a6b4e4a0c4fb97b565 69 Pfam PF03621 MbtH-like protein 4 54 3.5E-27 T 06-07-2017 IPR005153 MbtH-like protein SMD11_RS03030 d2f48734b34bf4a6b4e4a0c4fb97b565 69 SMART SM00923 5 55 7.9E-28 T 06-07-2017 IPR005153 MbtH-like protein SMD11_RS28955 d0af8a6244db66d4117a4e09efbc8202 349 Pfam PF00348 Polyprenyl synthetase 56 283 6.5E-49 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 SMD11_RS28955 d0af8a6244db66d4117a4e09efbc8202 349 Gene3D G3DSA:1.10.600.10 56 348 1.8E-77 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS28955 d0af8a6244db66d4117a4e09efbc8202 349 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 97 111 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 SMD11_RS28955 d0af8a6244db66d4117a4e09efbc8202 349 SUPERFAMILY SSF48576 40 348 2.4E-76 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 ProSitePatterns PS00012 Phosphopantetheine attachment site. 538 553 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 Pfam PF00550 Phosphopantetheine attachment site 512 564 2.0E-5 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 Pfam PF00550 Phosphopantetheine attachment site 407 459 2.0E-5 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 ProSitePatterns PS00012 Phosphopantetheine attachment site. 433 448 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 Pfam PF00698 Acyl transferase domain 11 299 4.4E-24 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 Gene3D G3DSA:3.30.70.250 139 197 1.5E-7 T 06-07-2017 SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 10 313 7.8E-22 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 Gene3D G3DSA:1.10.1200.10 506 583 3.7E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 Gene3D G3DSA:1.10.1200.10 402 494 9.4E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 SUPERFAMILY SSF47336 402 492 5.5E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 Gene3D G3DSA:3.40.366.10 4 133 1.2E-43 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 Gene3D G3DSA:3.40.366.10 203 305 1.2E-43 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 SUPERFAMILY SSF52151 6 139 8.11E-43 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 SUPERFAMILY SSF52151 205 299 8.11E-43 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 SUPERFAMILY SSF47336 507 591 2.75E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS20340 185af33f00f8cf67261ab260b4d3b770 594 SUPERFAMILY SSF55048 139 196 4.05E-8 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS06585 2aa2e5c7a3c949e45b52093a6a151262 196 SUPERFAMILY SSF53597 3 195 1.19E-25 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD11_RS06585 2aa2e5c7a3c949e45b52093a6a151262 196 Gene3D G3DSA:3.40.430.10 3 195 4.2E-27 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD11_RS06585 2aa2e5c7a3c949e45b52093a6a151262 196 Pfam PF01872 RibD C-terminal domain 3 187 9.8E-25 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD11_RS07105 e67b03322408d41e58a2060d6be38c4f 408 Pfam PF02625 XdhC and CoxI family 119 183 1.4E-8 T 06-07-2017 IPR003777 XdhC- CoxI SMD11_RS07105 e67b03322408d41e58a2060d6be38c4f 408 Pfam PF02625 XdhC and CoxI family 11 78 1.2E-22 T 06-07-2017 IPR003777 XdhC- CoxI SMD11_RS07105 e67b03322408d41e58a2060d6be38c4f 408 Pfam PF13478 XdhC Rossmann domain 227 369 2.1E-40 T 06-07-2017 IPR027051 XdhC Rossmann domain SMD11_RS03230 e8e42a98bd5c16315f57f5105c405bcf 126 Pfam PF00085 Thioredoxin 40 120 2.3E-7 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 SMD11_RS03230 e8e42a98bd5c16315f57f5105c405bcf 126 Gene3D G3DSA:3.40.30.10 35 122 2.7E-12 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS03230 e8e42a98bd5c16315f57f5105c405bcf 126 SUPERFAMILY SSF52833 38 122 6.5E-14 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS07810 7a4289952b781523c6bd64900acc376a 333 SUPERFAMILY SSF51430 1 312 8.38E-96 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS07810 7a4289952b781523c6bd64900acc376a 333 Gene3D G3DSA:3.20.20.100 1 326 5.9E-105 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS07810 7a4289952b781523c6bd64900acc376a 333 Pfam PF00248 Aldo/keto reductase family 17 312 1.4E-70 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS27305 0a6bf2ebdbf63a6c85e39ca53df57823 363 PIRSF PIRSF001455 12 360 3.8E-98 T 06-07-2017 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMD11_RS27305 0a6bf2ebdbf63a6c85e39ca53df57823 363 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 8 360 36.122 T 06-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMD11_RS27305 0a6bf2ebdbf63a6c85e39ca53df57823 363 Gene3D G3DSA:1.20.1090.10 177 355 2.8E-59 T 06-07-2017 SMD11_RS27305 0a6bf2ebdbf63a6c85e39ca53df57823 363 Gene3D G3DSA:3.40.50.1970 14 175 3.4E-53 T 06-07-2017 SMD11_RS27305 0a6bf2ebdbf63a6c85e39ca53df57823 363 SUPERFAMILY SSF56796 15 357 3.93E-97 T 06-07-2017 SMD11_RS27305 0a6bf2ebdbf63a6c85e39ca53df57823 363 Pfam PF01761 3-dehydroquinate synthase 71 327 1.7E-92 T 06-07-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMD11_RS27305 0a6bf2ebdbf63a6c85e39ca53df57823 363 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 19 346 2.2E-105 T 06-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMD11_RS19095 ce4a7a7eb75ac295203fbbb559645f14 615 Gene3D G3DSA:3.40.50.10490 445 615 7.8E-62 T 06-07-2017 SMD11_RS19095 ce4a7a7eb75ac295203fbbb559645f14 615 SUPERFAMILY SSF53697 247 615 2.13E-111 T 06-07-2017 SMD11_RS19095 ce4a7a7eb75ac295203fbbb559645f14 615 Gene3D G3DSA:3.40.50.10490 246 444 1.9E-75 T 06-07-2017 SMD11_RS19095 ce4a7a7eb75ac295203fbbb559645f14 615 Gene3D G3DSA:3.60.20.10 2 242 3.7E-74 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS19095 ce4a7a7eb75ac295203fbbb559645f14 615 Pfam PF13522 Glutamine amidotransferase domain 68 194 6.2E-22 T 06-07-2017 SMD11_RS19095 ce4a7a7eb75ac295203fbbb559645f14 615 SUPERFAMILY SSF56235 2 233 4.55E-66 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS19095 ce4a7a7eb75ac295203fbbb559645f14 615 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 615 8.3E-248 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SMD11_RS19095 ce4a7a7eb75ac295203fbbb559645f14 615 Pfam PF01380 SIS domain 292 418 5.0E-35 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 SMD11_RS19095 ce4a7a7eb75ac295203fbbb559645f14 615 Pfam PF01380 SIS domain 464 596 1.7E-23 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 SMD11_RS19095 ce4a7a7eb75ac295203fbbb559645f14 615 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 615 41.3 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SMD11_RS06650 a53d554eb41cecb0052a6014572fddf9 184 SUPERFAMILY SSF52499 8 182 5.89E-51 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS06650 a53d554eb41cecb0052a6014572fddf9 184 Gene3D G3DSA:3.40.50.850 8 180 2.2E-53 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS06650 a53d554eb41cecb0052a6014572fddf9 184 Pfam PF00857 Isochorismatase family 10 176 6.4E-40 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS03965 f23a9191eb9745c4b51cca46b4a5c6cd 145 Gene3D G3DSA:3.30.530.20 3 142 1.8E-15 T 06-07-2017 IPR023393 START-like domain SMD11_RS03965 f23a9191eb9745c4b51cca46b4a5c6cd 145 SUPERFAMILY SSF55961 1 140 3.3E-24 T 06-07-2017 SMD11_RS03965 f23a9191eb9745c4b51cca46b4a5c6cd 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 140 1.7E-14 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase SMD11_RS27565 b8b4c83abab012343b3164c8241370f4 695 Gene3D G3DSA:3.30.70.270 262 428 3.6E-56 T 06-07-2017 SMD11_RS27565 b8b4c83abab012343b3164c8241370f4 695 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 132 257 2.2E-24 T 06-07-2017 IPR000014 PAS domain SMD11_RS27565 b8b4c83abab012343b3164c8241370f4 695 SMART SM00052 433 684 5.0E-102 T 06-07-2017 IPR001633 EAL domain SMD11_RS27565 b8b4c83abab012343b3164c8241370f4 695 SMART SM00091 135 201 1.9E-11 T 06-07-2017 IPR000014 PAS domain SMD11_RS27565 b8b4c83abab012343b3164c8241370f4 695 SMART SM00086 208 250 1.1E-6 T 06-07-2017 IPR001610 PAC motif SMD11_RS27565 b8b4c83abab012343b3164c8241370f4 695 Pfam PF00990 Diguanylate cyclase, GGDEF domain 261 419 3.6E-45 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS27565 b8b4c83abab012343b3164c8241370f4 695 SUPERFAMILY SSF55073 266 424 1.46E-45 T 06-07-2017 IPR029787 Nucleotide cyclase SMD11_RS27565 b8b4c83abab012343b3164c8241370f4 695 SUPERFAMILY SSF55785 123 248 9.02E-28 T 06-07-2017 IPR000014 PAS domain SMD11_RS27565 b8b4c83abab012343b3164c8241370f4 695 Gene3D G3DSA:3.20.20.450 437 689 1.2E-97 T 06-07-2017 IPR001633 EAL domain SMD11_RS27565 b8b4c83abab012343b3164c8241370f4 695 Gene3D G3DSA:3.30.450.20 123 248 2.6E-28 T 06-07-2017 SMD11_RS27565 b8b4c83abab012343b3164c8241370f4 695 Pfam PF00563 EAL domain 441 679 2.4E-69 T 06-07-2017 IPR001633 EAL domain SMD11_RS27565 b8b4c83abab012343b3164c8241370f4 695 Pfam PF08448 PAS fold 146 251 9.1E-14 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS27565 b8b4c83abab012343b3164c8241370f4 695 SUPERFAMILY SSF141868 439 688 4.45E-83 T 06-07-2017 IPR001633 EAL domain SMD11_RS27565 b8b4c83abab012343b3164c8241370f4 695 SMART SM00267 250 423 9.2E-66 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS27565 b8b4c83abab012343b3164c8241370f4 695 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 259 423 4.8E-38 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS00605 c187fa070a8acd49ab4c2307d9e69d15 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 1.8E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00605 c187fa070a8acd49ab4c2307d9e69d15 219 Gene3D G3DSA:1.10.357.10 3 212 1.1E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS00605 c187fa070a8acd49ab4c2307d9e69d15 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 4.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00605 c187fa070a8acd49ab4c2307d9e69d15 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 4.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00605 c187fa070a8acd49ab4c2307d9e69d15 219 SUPERFAMILY SSF48498 105 211 1.19E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS00605 c187fa070a8acd49ab4c2307d9e69d15 219 SUPERFAMILY SSF46689 14 93 2.72E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS03805 a0d822d445593f2a851c5cc563d43aa4 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS03805 a0d822d445593f2a851c5cc563d43aa4 263 Gene3D G3DSA:3.40.50.720 12 247 4.8E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03805 a0d822d445593f2a851c5cc563d43aa4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03805 a0d822d445593f2a851c5cc563d43aa4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03805 a0d822d445593f2a851c5cc563d43aa4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03805 a0d822d445593f2a851c5cc563d43aa4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 2.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03805 a0d822d445593f2a851c5cc563d43aa4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03805 a0d822d445593f2a851c5cc563d43aa4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03805 a0d822d445593f2a851c5cc563d43aa4 263 SUPERFAMILY SSF51735 11 247 3.22E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03805 a0d822d445593f2a851c5cc563d43aa4 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 9.7E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03805 a0d822d445593f2a851c5cc563d43aa4 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 9.7E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03805 a0d822d445593f2a851c5cc563d43aa4 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 9.7E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03805 a0d822d445593f2a851c5cc563d43aa4 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 247 1.7E-49 T 06-07-2017 SMD11_RS03805 a0d822d445593f2a851c5cc563d43aa4 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 182 2.5E-4 T 06-07-2017 SMD11_RS02660 24b2aaf16df041897305e3ebb659741d 334 Gene3D G3DSA:3.10.310.10 156 322 6.0E-62 T 06-07-2017 SMD11_RS02660 24b2aaf16df041897305e3ebb659741d 334 Gene3D G3DSA:3.10.310.10 3 155 7.8E-69 T 06-07-2017 SMD11_RS02660 24b2aaf16df041897305e3ebb659741d 334 SUPERFAMILY SSF54506 2 332 5.38E-116 T 06-07-2017 SMD11_RS02660 24b2aaf16df041897305e3ebb659741d 334 PIRSF PIRSF029792 1 334 1.7E-129 T 06-07-2017 IPR008794 Proline racemase family SMD11_RS02660 24b2aaf16df041897305e3ebb659741d 334 Pfam PF05544 Proline racemase 10 332 6.6E-128 T 06-07-2017 IPR008794 Proline racemase family SMD11_RS02375 f9fa5f54e8d335ae142221e6ec6a8779 109 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 9 102 2.4E-13 T 06-07-2017 IPR008407 Branched-chain amino acid transport, AzlD SMD11_RS02375 f9fa5f54e8d335ae142221e6ec6a8779 109 PIRSF PIRSF003203 1 107 3.6E-26 T 06-07-2017 IPR008407 Branched-chain amino acid transport, AzlD SMD11_RS32005 14857c6638bc848f80dbbec444822a87 250 Gene3D G3DSA:3.40.50.720 5 221 2.3E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32005 14857c6638bc848f80dbbec444822a87 250 SUPERFAMILY SSF51735 3 230 1.08E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32005 14857c6638bc848f80dbbec444822a87 250 Pfam PF00106 short chain dehydrogenase 7 187 2.4E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32005 14857c6638bc848f80dbbec444822a87 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS32005 14857c6638bc848f80dbbec444822a87 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32005 14857c6638bc848f80dbbec444822a87 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32005 14857c6638bc848f80dbbec444822a87 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32005 14857c6638bc848f80dbbec444822a87 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32005 14857c6638bc848f80dbbec444822a87 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32005 14857c6638bc848f80dbbec444822a87 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32005 14857c6638bc848f80dbbec444822a87 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32005 14857c6638bc848f80dbbec444822a87 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS15725 db181b24f74ddac488f2ab9bbe861d25 241 SUPERFAMILY SSF46894 171 234 9.52E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS15725 db181b24f74ddac488f2ab9bbe861d25 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 192 6.2E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS15725 db181b24f74ddac488f2ab9bbe861d25 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 208 6.2E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS15725 db181b24f74ddac488f2ab9bbe861d25 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 208 220 6.2E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS15725 db181b24f74ddac488f2ab9bbe861d25 241 Gene3D G3DSA:3.40.50.2300 10 179 4.6E-38 T 06-07-2017 SMD11_RS15725 db181b24f74ddac488f2ab9bbe861d25 241 SUPERFAMILY SSF52172 10 150 1.42E-28 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS15725 db181b24f74ddac488f2ab9bbe861d25 241 Pfam PF00072 Response regulator receiver domain 13 133 1.1E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS15725 db181b24f74ddac488f2ab9bbe861d25 241 Gene3D G3DSA:1.10.10.10 180 234 2.7E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15725 db181b24f74ddac488f2ab9bbe861d25 241 Pfam PF00196 Bacterial regulatory proteins, luxR family 176 232 1.0E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS15725 db181b24f74ddac488f2ab9bbe861d25 241 ProSitePatterns PS00622 LuxR-type HTH domain signature. 192 219 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS15725 db181b24f74ddac488f2ab9bbe861d25 241 SMART SM00421 175 232 5.1E-26 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS15725 db181b24f74ddac488f2ab9bbe861d25 241 SMART SM00448 11 132 1.1E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS24435 ce0e6af8bc60a80817591f2db0d558cd 204 SUPERFAMILY SSF48498 88 195 7.94E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS24435 ce0e6af8bc60a80817591f2db0d558cd 204 Gene3D G3DSA:1.10.357.10 67 197 4.2E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS24435 ce0e6af8bc60a80817591f2db0d558cd 204 Gene3D G3DSA:1.10.10.60 45 66 3.7E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS24435 ce0e6af8bc60a80817591f2db0d558cd 204 Gene3D G3DSA:1.10.10.60 6 44 1.6E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS24435 ce0e6af8bc60a80817591f2db0d558cd 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.8E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS24435 ce0e6af8bc60a80817591f2db0d558cd 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.8E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS24435 ce0e6af8bc60a80817591f2db0d558cd 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 5.1E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS24435 ce0e6af8bc60a80817591f2db0d558cd 204 SUPERFAMILY SSF46689 4 78 3.33E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS24390 4fac0ebef844519a33f9dc0ac1bc7dd0 266 SUPERFAMILY SSF110399 4 242 2.09E-83 T 06-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 SMD11_RS24390 4fac0ebef844519a33f9dc0ac1bc7dd0 266 Gene3D G3DSA:3.20.20.70 4 252 1.1E-59 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS24390 4fac0ebef844519a33f9dc0ac1bc7dd0 266 Pfam PF05690 Thiazole biosynthesis protein ThiG 8 250 1.5E-108 T 06-07-2017 SMD11_RS24390 4fac0ebef844519a33f9dc0ac1bc7dd0 266 Hamap MF_00443 Thiazole synthase [thiG]. 5 256 43.458 T 06-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 SMD11_RS03245 296a8ad6a912b5fd90af126c5406ccd1 252 Gene3D G3DSA:3.40.50.720 8 244 3.8E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03245 296a8ad6a912b5fd90af126c5406ccd1 252 SUPERFAMILY SSF51735 8 246 3.1E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03245 296a8ad6a912b5fd90af126c5406ccd1 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS03245 296a8ad6a912b5fd90af126c5406ccd1 252 Pfam PF00106 short chain dehydrogenase 14 184 2.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03245 296a8ad6a912b5fd90af126c5406ccd1 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 2.9E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03245 296a8ad6a912b5fd90af126c5406ccd1 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 2.9E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03245 296a8ad6a912b5fd90af126c5406ccd1 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.9E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03245 296a8ad6a912b5fd90af126c5406ccd1 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 2.9E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29210 1aa15f46bb278fb6cd664f75d6246e7c 333 Gene3D G3DSA:3.90.25.10 184 320 5.3E-29 T 06-07-2017 SMD11_RS29210 1aa15f46bb278fb6cd664f75d6246e7c 333 SUPERFAMILY SSF51735 7 324 2.79E-89 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29210 1aa15f46bb278fb6cd664f75d6246e7c 333 Gene3D G3DSA:3.40.50.720 7 183 3.4E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29210 1aa15f46bb278fb6cd664f75d6246e7c 333 Pfam PF16363 GDP-mannose 4,6 dehydratase 9 312 6.2E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05320 8266a0af35b290327e8d0dfbab109e02 216 Gene3D G3DSA:3.40.50.1580 35 181 4.3E-20 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD11_RS05320 8266a0af35b290327e8d0dfbab109e02 216 SUPERFAMILY SSF53167 11 180 1.83E-23 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD11_RS05320 8266a0af35b290327e8d0dfbab109e02 216 Pfam PF01048 Phosphorylase superfamily 36 176 8.8E-16 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD11_RS11105 6543c53d17787bcdfb652bd24aeb6cfb 253 Pfam PF00005 ABC transporter 20 178 2.6E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS11105 6543c53d17787bcdfb652bd24aeb6cfb 253 SUPERFAMILY SSF52540 4 248 6.31E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11105 6543c53d17787bcdfb652bd24aeb6cfb 253 Gene3D G3DSA:3.40.50.300 3 250 4.1E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11105 6543c53d17787bcdfb652bd24aeb6cfb 253 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS11105 6543c53d17787bcdfb652bd24aeb6cfb 253 SMART SM00382 29 226 1.4E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS11105 6543c53d17787bcdfb652bd24aeb6cfb 253 PIRSF PIRSF039085 1 253 6.0E-126 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMD11_RS02090 c5dc45ab5f7c0f9d50a21b19981b5d3e 439 Gene3D G3DSA:3.40.309.10 229 413 2.3E-61 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS02090 c5dc45ab5f7c0f9d50a21b19981b5d3e 439 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 214 221 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS02090 c5dc45ab5f7c0f9d50a21b19981b5d3e 439 Pfam PF00171 Aldehyde dehydrogenase family 10 433 3.9E-88 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS02090 c5dc45ab5f7c0f9d50a21b19981b5d3e 439 Gene3D G3DSA:3.40.605.10 10 228 1.8E-62 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS02090 c5dc45ab5f7c0f9d50a21b19981b5d3e 439 PIRSF PIRSF036492 3 439 7.5E-178 T 06-07-2017 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 SMD11_RS02090 c5dc45ab5f7c0f9d50a21b19981b5d3e 439 SUPERFAMILY SSF53720 11 436 2.09E-126 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS02090 c5dc45ab5f7c0f9d50a21b19981b5d3e 439 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 242 253 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS32210 7a0517233166027a227421f22e8aec59 798 PIRSF PIRSF009393 5 769 1.6E-244 T 06-07-2017 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 SMD11_RS32210 7a0517233166027a227421f22e8aec59 798 SUPERFAMILY SSF55904 622 764 7.85E-33 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 SMD11_RS32210 7a0517233166027a227421f22e8aec59 798 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 627 756 1.2E-44 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 SMD11_RS32210 7a0517233166027a227421f22e8aec59 798 SUPERFAMILY SSF53383 145 619 2.59E-98 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS32210 7a0517233166027a227421f22e8aec59 798 SUPERFAMILY SSF52172 24 104 2.4E-6 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS32210 7a0517233166027a227421f22e8aec59 798 Gene3D G3DSA:3.90.100.10 645 758 5.0E-27 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 SMD11_RS32210 7a0517233166027a227421f22e8aec59 798 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 22 139 3.0E-21 T 06-07-2017 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 SMD11_RS32210 7a0517233166027a227421f22e8aec59 798 Gene3D G3DSA:3.40.640.10 145 452 7.9E-99 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS32210 7a0517233166027a227421f22e8aec59 798 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 145 602 5.4E-145 T 06-07-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 SMD11_RS32210 7a0517233166027a227421f22e8aec59 798 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 389 403 - T 06-07-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 SMD11_RS32210 7a0517233166027a227421f22e8aec59 798 Gene3D G3DSA:3.90.1150.10 457 644 5.2E-67 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS32210 7a0517233166027a227421f22e8aec59 798 Gene3D G3DSA:3.40.50.2300 26 105 1.4E-7 T 06-07-2017 SMD11_RS11860 7a112dedf8d0275ae92d483bb656ffc8 286 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 50 63 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS11860 7a112dedf8d0275ae92d483bb656ffc8 286 Gene3D G3DSA:3.20.20.20 11 274 5.7E-86 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS11860 7a112dedf8d0275ae92d483bb656ffc8 286 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 16 31 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS11860 7a112dedf8d0275ae92d483bb656ffc8 286 SUPERFAMILY SSF51717 4 276 1.7E-81 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS11860 7a112dedf8d0275ae92d483bb656ffc8 286 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 271 9.3E-82 T 06-07-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 SMD11_RS11860 7a112dedf8d0275ae92d483bb656ffc8 286 Pfam PF00809 Pterin binding enzyme 17 257 2.2E-64 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS13195 d247c759741818f8722dfc6b3bfcc5f0 373 Gene3D G3DSA:1.10.260.40 18 76 4.8E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS13195 d247c759741818f8722dfc6b3bfcc5f0 373 Pfam PF13560 Helix-turn-helix domain 18 74 4.2E-12 T 06-07-2017 SMD11_RS13195 d247c759741818f8722dfc6b3bfcc5f0 373 SMART SM00530 21 76 6.8E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS13195 d247c759741818f8722dfc6b3bfcc5f0 373 SUPERFAMILY SSF47413 16 78 1.13E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS13195 d247c759741818f8722dfc6b3bfcc5f0 373 Pfam PF10901 Protein of unknown function (DUF2690) 258 351 5.7E-21 T 06-07-2017 IPR021224 Protein of unknown function DUF2690 SMD11_RS23790 70cd639cfa63febecff3be29a124429d 344 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 24 323 6.4E-114 T 06-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMD11_RS23790 70cd639cfa63febecff3be29a124429d 344 Pfam PF13732 Domain of unknown function (DUF4162) 229 321 5.2E-7 T 06-07-2017 IPR025302 Domain of unknown function DUF4162 SMD11_RS23790 70cd639cfa63febecff3be29a124429d 344 Gene3D G3DSA:3.40.50.300 13 239 1.2E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23790 70cd639cfa63febecff3be29a124429d 344 SUPERFAMILY SSF52540 17 238 1.02E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23790 70cd639cfa63febecff3be29a124429d 344 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS23790 70cd639cfa63febecff3be29a124429d 344 SMART SM00382 41 232 9.8E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS23790 70cd639cfa63febecff3be29a124429d 344 Pfam PF00005 ABC transporter 32 175 3.0E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS10545 802911640592d43e52b68bb60d0627ee 285 ProSitePatterns PS00498 Tyrosinase and hemocyanins CuB-binding region signature. 214 225 - T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS10545 802911640592d43e52b68bb60d0627ee 285 ProSitePatterns PS00497 Tyrosinase CuA-binding region signature. 54 71 - T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS10545 802911640592d43e52b68bb60d0627ee 285 SUPERFAMILY SSF48056 1 282 3.14E-61 T 06-07-2017 IPR008922 Uncharacterised domain, di-copper centre SMD11_RS10545 802911640592d43e52b68bb60d0627ee 285 Pfam PF00264 Common central domain of tyrosinase 30 234 9.3E-40 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS10545 802911640592d43e52b68bb60d0627ee 285 PRINTS PR00092 Tyrosinase copper-binding domain signature 194 205 8.0E-17 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS10545 802911640592d43e52b68bb60d0627ee 285 PRINTS PR00092 Tyrosinase copper-binding domain signature 213 231 8.0E-17 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS10545 802911640592d43e52b68bb60d0627ee 285 PRINTS PR00092 Tyrosinase copper-binding domain signature 83 88 8.0E-17 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS10545 802911640592d43e52b68bb60d0627ee 285 PRINTS PR00092 Tyrosinase copper-binding domain signature 54 71 8.0E-17 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS10545 802911640592d43e52b68bb60d0627ee 285 Gene3D G3DSA:1.10.1280.10 1 282 1.3E-61 T 06-07-2017 IPR008922 Uncharacterised domain, di-copper centre SMD11_RS07075 4dff31af721098942d9ec82d77995e12 256 Gene3D G3DSA:2.60.120.10 26 149 1.2E-8 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS07075 4dff31af721098942d9ec82d77995e12 256 SUPERFAMILY SSF46785 160 238 2.22E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07075 4dff31af721098942d9ec82d77995e12 256 Pfam PF13545 Crp-like helix-turn-helix domain 160 236 1.2E-7 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMD11_RS07075 4dff31af721098942d9ec82d77995e12 256 Gene3D G3DSA:1.10.10.10 160 238 3.6E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07075 4dff31af721098942d9ec82d77995e12 256 SUPERFAMILY SSF51206 26 149 9.43E-13 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like SMD11_RS08985 d65a003cfd2d52f96ca6eb81694ac9ec 156 Pfam PF00210 Ferritin-like domain 18 153 3.0E-21 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 SMD11_RS08985 d65a003cfd2d52f96ca6eb81694ac9ec 156 SUPERFAMILY SSF47240 3 153 1.11E-44 T 06-07-2017 IPR009078 Ferritin-like superfamily SMD11_RS08985 d65a003cfd2d52f96ca6eb81694ac9ec 156 PIRSF PIRSF005900 1 156 4.2E-42 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMD11_RS08985 d65a003cfd2d52f96ca6eb81694ac9ec 156 ProSitePatterns PS00818 Dps protein family signature 1. 38 54 - T 06-07-2017 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 SMD11_RS08985 d65a003cfd2d52f96ca6eb81694ac9ec 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 133 151 1.7E-11 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMD11_RS08985 d65a003cfd2d52f96ca6eb81694ac9ec 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 38 54 1.7E-11 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMD11_RS08985 d65a003cfd2d52f96ca6eb81694ac9ec 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 62 78 1.7E-11 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SMD11_RS08985 d65a003cfd2d52f96ca6eb81694ac9ec 156 Gene3D G3DSA:1.20.1260.10 2 153 9.3E-45 T 06-07-2017 IPR012347 Ferritin-related SMD11_RS04600 5feb0156403640e6d738481781c4f720 408 Gene3D G3DSA:1.10.630.10 3 406 4.9E-112 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS04600 5feb0156403640e6d738481781c4f720 408 Pfam PF00067 Cytochrome P450 34 157 8.8E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS04600 5feb0156403640e6d738481781c4f720 408 Pfam PF00067 Cytochrome P450 285 381 3.8E-20 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS04600 5feb0156403640e6d738481781c4f720 408 SUPERFAMILY SSF48264 4 406 7.33E-86 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS04600 5feb0156403640e6d738481781c4f720 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 352 361 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS04600 5feb0156403640e6d738481781c4f720 408 PRINTS PR00359 B-class P450 signature 359 370 4.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04600 5feb0156403640e6d738481781c4f720 408 PRINTS PR00359 B-class P450 signature 93 104 4.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04600 5feb0156403640e6d738481781c4f720 408 PRINTS PR00359 B-class P450 signature 329 344 4.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04600 5feb0156403640e6d738481781c4f720 408 PRINTS PR00359 B-class P450 signature 203 225 4.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04600 5feb0156403640e6d738481781c4f720 408 PRINTS PR00359 B-class P450 signature 350 359 4.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04600 5feb0156403640e6d738481781c4f720 408 PRINTS PR00359 B-class P450 signature 160 175 4.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04600 5feb0156403640e6d738481781c4f720 408 PRINTS PR00359 B-class P450 signature 284 295 4.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04600 5feb0156403640e6d738481781c4f720 408 PRINTS PR00359 B-class P450 signature 143 159 4.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS04600 5feb0156403640e6d738481781c4f720 408 PRINTS PR00359 B-class P450 signature 301 328 4.5E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS18420 1c5c45f87d4ec943e57f122764e61e22 306 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 19 300 6.3E-86 T 06-07-2017 IPR006371 4-hydroxybenzoate polyprenyltransferase-related SMD11_RS18420 1c5c45f87d4ec943e57f122764e61e22 306 Pfam PF01040 UbiA prenyltransferase family 41 284 2.7E-50 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 SMD11_RS12680 11d206c521f55c56ac6abc6b31db0363 476 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 283 294 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS12680 11d206c521f55c56ac6abc6b31db0363 476 Pfam PF00171 Aldehyde dehydrogenase family 30 475 8.0E-167 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS12680 11d206c521f55c56ac6abc6b31db0363 476 Gene3D G3DSA:3.40.309.10 270 454 1.0E-64 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS12680 11d206c521f55c56ac6abc6b31db0363 476 Gene3D G3DSA:3.40.605.10 20 269 1.6E-98 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS12680 11d206c521f55c56ac6abc6b31db0363 476 SUPERFAMILY SSF53720 18 475 1.96E-164 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS00955 3715464691b00eb7698d163b694a46fd 312 Pfam PF00756 Putative esterase 44 305 1.0E-54 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 SMD11_RS00955 3715464691b00eb7698d163b694a46fd 312 SUPERFAMILY SSF53474 230 291 1.02E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS00955 3715464691b00eb7698d163b694a46fd 312 SUPERFAMILY SSF53474 33 201 1.02E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS00955 3715464691b00eb7698d163b694a46fd 312 Gene3D G3DSA:3.40.50.1820 34 293 3.0E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS05160 ef18a82ca4bbccd08958e3cd97f12a52 802 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 737 786 2.1E-6 T 06-07-2017 IPR005194 Glycoside hydrolase family 65, C-terminal SMD11_RS05160 ef18a82ca4bbccd08958e3cd97f12a52 802 PIRSF PIRSF036289 1 787 1.0E-205 T 06-07-2017 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase SMD11_RS05160 ef18a82ca4bbccd08958e3cd97f12a52 802 Gene3D G3DSA:2.70.98.40 3 267 1.0E-77 T 06-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 SMD11_RS05160 ef18a82ca4bbccd08958e3cd97f12a52 802 SUPERFAMILY SSF74650 3 266 5.02E-61 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMD11_RS05160 ef18a82ca4bbccd08958e3cd97f12a52 802 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 8 265 1.3E-64 T 06-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 SMD11_RS05160 ef18a82ca4bbccd08958e3cd97f12a52 802 Gene3D G3DSA:1.50.10.10 314 715 5.9E-122 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 SMD11_RS05160 ef18a82ca4bbccd08958e3cd97f12a52 802 SUPERFAMILY SSF48208 272 778 3.06E-95 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD11_RS05160 ef18a82ca4bbccd08958e3cd97f12a52 802 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 317 729 6.5E-142 T 06-07-2017 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 SMD11_RS17530 3d744359910bc87bad975d72bcd0983e 288 SUPERFAMILY SSF53335 14 286 1.86E-53 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS17530 3d744359910bc87bad975d72bcd0983e 288 Gene3D G3DSA:3.40.50.150 11 273 9.5E-52 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS17530 3d744359910bc87bad975d72bcd0983e 288 Pfam PF08241 Methyltransferase domain 81 177 4.0E-23 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS15585 51241d34bf5458281c87dffbc745b757 294 SUPERFAMILY SSF56534 20 284 5.23E-70 T 06-07-2017 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 SMD11_RS15585 51241d34bf5458281c87dffbc745b757 294 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 215 233 2.0E-10 T 06-07-2017 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 SMD11_RS15585 51241d34bf5458281c87dffbc745b757 294 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 110 132 2.0E-10 T 06-07-2017 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 SMD11_RS15585 51241d34bf5458281c87dffbc745b757 294 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 23 42 2.0E-10 T 06-07-2017 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 SMD11_RS15585 51241d34bf5458281c87dffbc745b757 294 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 21 275 4.1E-56 T 06-07-2017 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 SMD11_RS15585 51241d34bf5458281c87dffbc745b757 294 Gene3D G3DSA:1.10.800.10 20 281 5.5E-73 T 06-07-2017 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 SMD11_RS21490 d26fb64e1408b3e86026e01ac5d46186 311 TIGRFAM TIGR03226 PhnU: 2-aminoethylphosphonate ABC transporter, permease protein 15 289 2.8E-90 T 06-07-2017 IPR017636 2-aminoethylphosphonate ABC transporter system, permease protein phnU GO:0016020|GO:0033223 SMD11_RS21490 d26fb64e1408b3e86026e01ac5d46186 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 287 2.1E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21490 d26fb64e1408b3e86026e01ac5d46186 311 SUPERFAMILY SSF161098 17 287 9.55E-49 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21490 d26fb64e1408b3e86026e01ac5d46186 311 Gene3D G3DSA:1.10.3720.10 25 290 1.1E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS29560 0f6c2e7aa4b2a721d77af3d0997d6af3 310 Gene3D G3DSA:3.40.50.720 17 175 1.2E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29560 0f6c2e7aa4b2a721d77af3d0997d6af3 310 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 22 172 7.8E-20 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD11_RS29560 0f6c2e7aa4b2a721d77af3d0997d6af3 310 PIRSF PIRSF000103 14 309 1.2E-35 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD11_RS29560 0f6c2e7aa4b2a721d77af3d0997d6af3 310 SUPERFAMILY SSF51735 22 175 6.36E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29255 80a51adcffbd25d545c6ecf4de1644f8 411 Gene3D G3DSA:3.30.565.10 284 402 1.9E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS29255 80a51adcffbd25d545c6ecf4de1644f8 411 Pfam PF07730 Histidine kinase 202 269 1.5E-7 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS29255 80a51adcffbd25d545c6ecf4de1644f8 411 SMART SM00387 305 401 7.9E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS29255 80a51adcffbd25d545c6ecf4de1644f8 411 SUPERFAMILY SSF55874 264 398 1.44E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS29255 80a51adcffbd25d545c6ecf4de1644f8 411 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 306 400 6.2E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS05340 e67be48dfaef046c35f3a58260f5b481 316 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 141 156 - T 06-07-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 SMD11_RS05340 e67be48dfaef046c35f3a58260f5b481 316 Gene3D G3DSA:1.10.600.10 16 300 8.9E-80 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS05340 e67be48dfaef046c35f3a58260f5b481 316 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 26 298 1.6E-93 T 06-07-2017 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 SMD11_RS05340 e67be48dfaef046c35f3a58260f5b481 316 SUPERFAMILY SSF48576 18 301 1.42E-72 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS05340 e67be48dfaef046c35f3a58260f5b481 316 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 176 201 - T 06-07-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 SMD11_RS05340 e67be48dfaef046c35f3a58260f5b481 316 Pfam PF00494 Squalene/phytoene synthase 29 289 4.2E-72 T 06-07-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 SMD11_RS18085 d54a516b9371f554c9e15df3e5a95b93 604 SUPERFAMILY SSF52540 109 292 7.09E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18085 d54a516b9371f554c9e15df3e5a95b93 604 Pfam PF00176 SNF2 family N-terminal domain 147 360 4.2E-17 T 06-07-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 SMD11_RS18085 d54a516b9371f554c9e15df3e5a95b93 604 Gene3D G3DSA:3.40.50.300 418 531 5.3E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18085 d54a516b9371f554c9e15df3e5a95b93 604 SMART SM00487 120 300 2.7E-9 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS18085 d54a516b9371f554c9e15df3e5a95b93 604 SUPERFAMILY SSF52540 412 572 9.52E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18085 d54a516b9371f554c9e15df3e5a95b93 604 SUPERFAMILY SSF52540 234 289 9.52E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18085 d54a516b9371f554c9e15df3e5a95b93 604 Gene3D G3DSA:3.40.50.300 123 285 7.4E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26990 3c320cd96fa9ee895556909adb67c9f0 1400 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 829 1034 3.9E-91 T 06-07-2017 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 SMD11_RS26990 3c320cd96fa9ee895556909adb67c9f0 1400 Gene3D G3DSA:3.40.50.10210 1123 1379 5.8E-112 T 06-07-2017 SMD11_RS26990 3c320cd96fa9ee895556909adb67c9f0 1400 Gene3D G3DSA:1.10.1610.10 1051 1122 4.5E-28 T 06-07-2017 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD11_RS26990 3c320cd96fa9ee895556909adb67c9f0 1400 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1063 1396 2.8E-125 T 06-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD11_RS26990 3c320cd96fa9ee895556909adb67c9f0 1400 Pfam PF00881 Nitroreductase family 841 1008 1.8E-31 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMD11_RS26990 3c320cd96fa9ee895556909adb67c9f0 1400 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 1061 1398 34.612 T 06-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD11_RS26990 3c320cd96fa9ee895556909adb67c9f0 1400 SUPERFAMILY SSF55469 837 1040 3.14E-52 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS26990 3c320cd96fa9ee895556909adb67c9f0 1400 Pfam PF02277 Phosphoribosyltransferase 1059 1396 7.9E-126 T 06-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD11_RS26990 3c320cd96fa9ee895556909adb67c9f0 1400 SUPERFAMILY SSF52733 1053 1397 3.79E-113 T 06-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD11_RS26990 3c320cd96fa9ee895556909adb67c9f0 1400 Gene3D G3DSA:3.40.109.10 833 1040 1.5E-51 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS03390 cfeb1a0108788096a3f9b2227dc9547d 234 Pfam PF17197 Domain of unknown function (DUF5134) 82 234 4.1E-35 T 06-07-2017 IPR033458 Protein of unknown function DUF5134 SMD11_RS03985 6aec213cd7267508c67a56ca32e84b70 287 Gene3D G3DSA:1.10.8.50 138 272 3.4E-35 T 06-07-2017 SMD11_RS03985 6aec213cd7267508c67a56ca32e84b70 287 SUPERFAMILY SSF46946 136 219 3.79E-23 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMD11_RS03985 6aec213cd7267508c67a56ca32e84b70 287 SMART SM01232 137 229 3.5E-29 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD11_RS03985 6aec213cd7267508c67a56ca32e84b70 287 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 91 2.0E-16 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD11_RS03985 6aec213cd7267508c67a56ca32e84b70 287 SUPERFAMILY SSF81624 2 142 3.53E-25 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD11_RS03985 6aec213cd7267508c67a56ca32e84b70 287 SUPERFAMILY SSF57716 233 272 5.99E-11 T 06-07-2017 SMD11_RS03985 6aec213cd7267508c67a56ca32e84b70 287 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 137 221 1.2E-21 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SMD11_RS03985 6aec213cd7267508c67a56ca32e84b70 287 Pfam PF06827 Zinc finger found in FPG and IleRS 244 271 2.9E-6 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 SMD11_RS03985 6aec213cd7267508c67a56ca32e84b70 287 Gene3D G3DSA:3.20.190.10 2 137 2.0E-21 T 06-07-2017 SMD11_RS03985 6aec213cd7267508c67a56ca32e84b70 287 SMART SM00898 2 123 3.3E-25 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SMD11_RS12785 351c7e71c55122d2a1ab0dd00c291d13 189 Gene3D G3DSA:2.40.320.10 2 181 1.3E-19 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 SMD11_RS12785 351c7e71c55122d2a1ab0dd00c291d13 189 SUPERFAMILY SSF55154 1 173 2.45E-20 T 06-07-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 SMD11_RS12785 351c7e71c55122d2a1ab0dd00c291d13 189 Pfam PF01928 CYTH domain 1 161 2.0E-20 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 SMD11_RS12785 351c7e71c55122d2a1ab0dd00c291d13 189 SMART SM01118 1 182 9.4E-8 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 SMD11_RS12785 351c7e71c55122d2a1ab0dd00c291d13 189 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 1 116 5.0E-8 T 06-07-2017 SMD11_RS17225 6fcb5b8067864cc4dca82243e2f1f1c3 346 Gene3D G3DSA:3.30.200.20 3 93 2.2E-13 T 06-07-2017 SMD11_RS17225 6fcb5b8067864cc4dca82243e2f1f1c3 346 Pfam PF01636 Phosphotransferase enzyme family 19 282 5.4E-30 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase SMD11_RS17225 6fcb5b8067864cc4dca82243e2f1f1c3 346 Gene3D G3DSA:3.90.1200.10 96 333 3.4E-22 T 06-07-2017 SMD11_RS17225 6fcb5b8067864cc4dca82243e2f1f1c3 346 SUPERFAMILY SSF56112 163 315 8.6E-44 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS17225 6fcb5b8067864cc4dca82243e2f1f1c3 346 SUPERFAMILY SSF56112 2 125 8.6E-44 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS23415 17b531b0fd40a259c7a3a736f48a506e 695 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 30 438 1.1E-82 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS23415 17b531b0fd40a259c7a3a736f48a506e 695 Gene3D G3DSA:1.20.1250.20 490 514 2.5E-20 T 06-07-2017 SMD11_RS23415 17b531b0fd40a259c7a3a736f48a506e 695 Gene3D G3DSA:1.20.1250.20 281 443 2.5E-20 T 06-07-2017 SMD11_RS23415 17b531b0fd40a259c7a3a736f48a506e 695 Gene3D G3DSA:1.20.1250.20 32 207 5.0E-36 T 06-07-2017 SMD11_RS23415 17b531b0fd40a259c7a3a736f48a506e 695 SUPERFAMILY SSF103473 485 514 4.97E-74 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS23415 17b531b0fd40a259c7a3a736f48a506e 695 SUPERFAMILY SSF103473 14 211 4.97E-74 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS23415 17b531b0fd40a259c7a3a736f48a506e 695 SUPERFAMILY SSF103473 265 437 4.97E-74 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS23415 17b531b0fd40a259c7a3a736f48a506e 695 SUPERFAMILY SSF46785 554 664 8.82E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23415 17b531b0fd40a259c7a3a736f48a506e 695 Pfam PF07690 Major Facilitator Superfamily 35 427 2.3E-54 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS23415 17b531b0fd40a259c7a3a736f48a506e 695 Gene3D G3DSA:1.10.10.10 554 664 1.0E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08295 407c144fe5f6c128f3a8ee81627c06d4 422 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 402 1.0E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08295 407c144fe5f6c128f3a8ee81627c06d4 422 SUPERFAMILY SSF55874 276 401 5.76E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08295 407c144fe5f6c128f3a8ee81627c06d4 422 Gene3D G3DSA:3.30.565.10 282 401 5.2E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08295 407c144fe5f6c128f3a8ee81627c06d4 422 Pfam PF07730 Histidine kinase 206 273 1.7E-18 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS08295 407c144fe5f6c128f3a8ee81627c06d4 422 SMART SM00387 311 405 2.9E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08295 407c144fe5f6c128f3a8ee81627c06d4 422 PIRSF PIRSF037434 8 408 1.8E-74 T 06-07-2017 IPR017205 Signal transduction histidine kinase, ChrS SMD11_RS08295 407c144fe5f6c128f3a8ee81627c06d4 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 361 7.4E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS08295 407c144fe5f6c128f3a8ee81627c06d4 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 383 7.4E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS08295 407c144fe5f6c128f3a8ee81627c06d4 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 402 7.4E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS14710 a1b15354fe375730b9c845cb4cae3117 310 SUPERFAMILY SSF53067 2 125 6.48E-31 T 06-07-2017 SMD11_RS14710 a1b15354fe375730b9c845cb4cae3117 310 Gene3D G3DSA:3.30.420.40 1 123 5.8E-34 T 06-07-2017 SMD11_RS14710 a1b15354fe375730b9c845cb4cae3117 310 Pfam PF02541 Ppx/GppA phosphatase family 26 305 7.3E-70 T 06-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 SMD11_RS14710 a1b15354fe375730b9c845cb4cae3117 310 SUPERFAMILY SSF53067 129 306 5.18E-37 T 06-07-2017 SMD11_RS14710 a1b15354fe375730b9c845cb4cae3117 310 Gene3D G3DSA:3.30.420.150 125 305 9.5E-48 T 06-07-2017 SMD11_RS03675 773427e7dd74db9522c72e1d013d77c7 303 Gene3D G3DSA:3.20.20.190 114 301 1.7E-6 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD11_RS03675 773427e7dd74db9522c72e1d013d77c7 303 SUPERFAMILY SSF51695 223 295 3.45E-11 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD11_RS03675 773427e7dd74db9522c72e1d013d77c7 303 SUPERFAMILY SSF51695 61 184 3.45E-11 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD11_RS03675 773427e7dd74db9522c72e1d013d77c7 303 Pfam PF13653 Glycerophosphoryl diester phosphodiesterase family 258 293 2.3E-10 T 06-07-2017 SMD11_RS30320 306cfa0dd8b0c92000936d731db8e5bb 463 PRINTS PR00465 E-class P450 group IV signature 307 323 3.6E-19 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30320 306cfa0dd8b0c92000936d731db8e5bb 463 PRINTS PR00465 E-class P450 group IV signature 396 414 3.6E-19 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30320 306cfa0dd8b0c92000936d731db8e5bb 463 PRINTS PR00465 E-class P450 group IV signature 251 277 3.6E-19 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30320 306cfa0dd8b0c92000936d731db8e5bb 463 PRINTS PR00465 E-class P450 group IV signature 380 396 3.6E-19 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30320 306cfa0dd8b0c92000936d731db8e5bb 463 PRINTS PR00465 E-class P450 group IV signature 356 374 3.6E-19 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30320 306cfa0dd8b0c92000936d731db8e5bb 463 PRINTS PR00465 E-class P450 group IV signature 14 31 3.6E-19 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30320 306cfa0dd8b0c92000936d731db8e5bb 463 PRINTS PR00465 E-class P450 group IV signature 340 354 3.6E-19 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30320 306cfa0dd8b0c92000936d731db8e5bb 463 SUPERFAMILY SSF48264 7 448 1.7E-102 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30320 306cfa0dd8b0c92000936d731db8e5bb 463 Gene3D G3DSA:1.10.630.10 6 449 4.1E-108 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30320 306cfa0dd8b0c92000936d731db8e5bb 463 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 389 398 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS30320 306cfa0dd8b0c92000936d731db8e5bb 463 PRINTS PR00385 P450 superfamily signature 260 277 3.0E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30320 306cfa0dd8b0c92000936d731db8e5bb 463 PRINTS PR00385 P450 superfamily signature 396 407 3.0E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30320 306cfa0dd8b0c92000936d731db8e5bb 463 PRINTS PR00385 P450 superfamily signature 387 396 3.0E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30320 306cfa0dd8b0c92000936d731db8e5bb 463 PRINTS PR00385 P450 superfamily signature 312 323 3.0E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30320 306cfa0dd8b0c92000936d731db8e5bb 463 Pfam PF00067 Cytochrome P450 8 436 1.2E-72 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS21530 af85344ccc86d99c97dd3214be8d8b1d 596 Gene3D G3DSA:3.90.550.10 171 405 3.2E-11 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS21530 af85344ccc86d99c97dd3214be8d8b1d 596 SUPERFAMILY SSF53448 165 429 7.99E-39 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS21530 af85344ccc86d99c97dd3214be8d8b1d 596 Pfam PF13506 Glycosyl transferase family 21 223 392 4.7E-18 T 06-07-2017 IPR025993 Ceramide glucosyltransferase GO:0016757 KEGG: 00600+2.4.1.80|MetaCyc: PWY-5129|Reactome: R-HSA-1660662 SMD11_RS25795 4537b15ac15167a66c38a046a70a92ae 547 Hamap MF_01227 CTP synthase [pyrG]. 8 545 50.351 T 06-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 SMD11_RS25795 4537b15ac15167a66c38a046a70a92ae 547 Pfam PF00117 Glutamine amidotransferase class-I 307 540 3.7E-49 T 06-07-2017 IPR017926 Glutamine amidotransferase SMD11_RS25795 4537b15ac15167a66c38a046a70a92ae 547 Gene3D G3DSA:3.40.50.300 6 290 1.8E-130 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25795 4537b15ac15167a66c38a046a70a92ae 547 SUPERFAMILY SSF52540 8 272 1.54E-117 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25795 4537b15ac15167a66c38a046a70a92ae 547 TIGRFAM TIGR00337 PyrG: CTP synthase 7 540 2.1E-230 T 06-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 SMD11_RS25795 4537b15ac15167a66c38a046a70a92ae 547 Gene3D G3DSA:3.40.50.880 294 546 1.1E-87 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS25795 4537b15ac15167a66c38a046a70a92ae 547 SUPERFAMILY SSF52317 294 545 6.48E-71 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS25795 4537b15ac15167a66c38a046a70a92ae 547 Pfam PF06418 CTP synthase N-terminus 9 272 9.4E-122 T 06-07-2017 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 SMD11_RS01475 3b9c3c2831d54dea88069c37be95f63f 200 Pfam PF00652 Ricin-type beta-trefoil lectin domain 112 198 3.8E-14 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS01475 3b9c3c2831d54dea88069c37be95f63f 200 SMART SM00458 65 199 1.3E-15 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS01475 3b9c3c2831d54dea88069c37be95f63f 200 SUPERFAMILY SSF50370 67 198 1.78E-26 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS01475 3b9c3c2831d54dea88069c37be95f63f 200 Gene3D G3DSA:2.80.10.50 73 198 5.8E-26 T 06-07-2017 SMD11_RS13915 6985015f4500d31f59afbcd20798f3ab 91 Gene3D G3DSA:3.10.20.30 3 89 9.0E-31 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS13915 6985015f4500d31f59afbcd20798f3ab 91 Pfam PF02597 ThiS family 5 91 1.7E-18 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 SMD11_RS13915 6985015f4500d31f59afbcd20798f3ab 91 SUPERFAMILY SSF54285 1 91 3.55E-24 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp SMD11_RS34215 a34feb07cda1c808d2e405198ad8832e 529 Gene3D G3DSA:1.20.1250.20 27 214 1.6E-37 T 06-07-2017 SMD11_RS34215 a34feb07cda1c808d2e405198ad8832e 529 Pfam PF07690 Major Facilitator Superfamily 34 426 1.5E-55 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS34215 a34feb07cda1c808d2e405198ad8832e 529 Gene3D G3DSA:1.20.1250.20 496 517 5.9E-20 T 06-07-2017 SMD11_RS34215 a34feb07cda1c808d2e405198ad8832e 529 Gene3D G3DSA:1.20.1250.20 280 438 5.9E-20 T 06-07-2017 SMD11_RS34215 a34feb07cda1c808d2e405198ad8832e 529 SUPERFAMILY SSF103473 265 436 5.49E-72 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS34215 a34feb07cda1c808d2e405198ad8832e 529 SUPERFAMILY SSF103473 495 523 5.49E-72 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS34215 a34feb07cda1c808d2e405198ad8832e 529 SUPERFAMILY SSF103473 16 213 5.49E-72 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS34215 a34feb07cda1c808d2e405198ad8832e 529 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 30 515 4.7E-85 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS32945 9cb68e9b104ff70b01a1c43c4d9c2d35 443 Pfam PF05977 Transmembrane secretion effector 17 416 1.0E-35 T 06-07-2017 IPR010290 Transmembrane secretion effector SMD11_RS32945 9cb68e9b104ff70b01a1c43c4d9c2d35 443 SUPERFAMILY SSF103473 19 409 1.26E-43 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS32945 9cb68e9b104ff70b01a1c43c4d9c2d35 443 Gene3D G3DSA:1.20.1250.20 238 411 5.8E-18 T 06-07-2017 SMD11_RS32945 9cb68e9b104ff70b01a1c43c4d9c2d35 443 Gene3D G3DSA:1.20.1250.20 20 201 6.0E-17 T 06-07-2017 SMD11_RS05175 99c3d18dfb1c305a8de19cece179df0c 321 Pfam PF00881 Nitroreductase family 110 301 5.3E-5 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMD11_RS05175 99c3d18dfb1c305a8de19cece179df0c 321 Gene3D G3DSA:3.40.109.10 225 317 4.9E-26 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS05175 99c3d18dfb1c305a8de19cece179df0c 321 Gene3D G3DSA:3.40.109.10 2 62 4.9E-26 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS05175 99c3d18dfb1c305a8de19cece179df0c 321 SUPERFAMILY SSF55469 2 73 1.13E-6 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS05175 99c3d18dfb1c305a8de19cece179df0c 321 SUPERFAMILY SSF55469 109 164 2.22E-9 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS05175 99c3d18dfb1c305a8de19cece179df0c 321 SUPERFAMILY SSF55469 227 319 2.22E-9 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS05635 c2dfb8ba57ac6e721cbced0ca4d356b4 143 Gene3D G3DSA:3.10.450.50 11 138 1.4E-17 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS05635 c2dfb8ba57ac6e721cbced0ca4d356b4 143 Pfam PF13577 SnoaL-like domain 13 135 5.9E-10 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain SMD11_RS05635 c2dfb8ba57ac6e721cbced0ca4d356b4 143 SUPERFAMILY SSF54427 2 141 2.25E-23 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS27700 82f52fd815244649ae6dc4f618abe960 674 Gene3D G3DSA:3.40.50.300 257 437 3.3E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27700 82f52fd815244649ae6dc4f618abe960 674 SUPERFAMILY SSF52540 228 474 1.77E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24205 b9fdb89eff5fc222c3675d3a86f53919 415 SUPERFAMILY SSF141523 239 364 4.97E-27 T 06-07-2017 SMD11_RS24205 b9fdb89eff5fc222c3675d3a86f53919 415 Pfam PF03734 L,D-transpeptidase catalytic domain 243 364 3.0E-14 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMD11_RS24205 b9fdb89eff5fc222c3675d3a86f53919 415 Gene3D G3DSA:2.40.440.10 243 366 1.1E-17 T 06-07-2017 SMD11_RS04750 49585cea3831181b383658a996973387 151 Pfam PF00583 Acetyltransferase (GNAT) family 52 128 2.4E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS04750 49585cea3831181b383658a996973387 151 SUPERFAMILY SSF55729 1 134 2.06E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS04750 49585cea3831181b383658a996973387 151 Gene3D G3DSA:3.40.630.30 30 149 6.0E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS12915 6fab545846b283542009253afb5a757f 516 Pfam PF00561 alpha/beta hydrolase fold 97 483 5.6E-23 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS12915 6fab545846b283542009253afb5a757f 516 SUPERFAMILY SSF53474 91 147 3.82E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12915 6fab545846b283542009253afb5a757f 516 SUPERFAMILY SSF53474 192 246 3.82E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12915 6fab545846b283542009253afb5a757f 516 SUPERFAMILY SSF53474 382 487 3.82E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12915 6fab545846b283542009253afb5a757f 516 Gene3D G3DSA:3.40.50.1820 61 146 8.8E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12915 6fab545846b283542009253afb5a757f 516 Gene3D G3DSA:3.40.50.1820 379 499 8.8E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12915 6fab545846b283542009253afb5a757f 516 Gene3D G3DSA:3.40.50.1820 190 310 8.8E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS22020 59e0c869ec293fdd68cdebb0d73a09ad 479 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 119 167 2.9E-15 T 06-07-2017 IPR023849 Uncharacterised domain CHP03934, TQXA SMD11_RS03710 1a0fef0ec23f30fcf543176d9ddfa4fd 305 SUPERFAMILY SSF103481 31 130 1.83E-14 T 06-07-2017 SMD11_RS03710 1a0fef0ec23f30fcf543176d9ddfa4fd 305 Pfam PF00892 EamA-like transporter family 3 128 6.0E-22 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS03710 1a0fef0ec23f30fcf543176d9ddfa4fd 305 Pfam PF00892 EamA-like transporter family 139 272 8.6E-17 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS03710 1a0fef0ec23f30fcf543176d9ddfa4fd 305 SUPERFAMILY SSF103481 181 275 6.15E-11 T 06-07-2017 SMD11_RS09555 494c05c81ddc83ee07697522f7e85906 102 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 1.6E-52 T 06-07-2017 IPR019592 Protein of unknown function DUF2469 SMD11_RS28185 cc449fb287d94b38db41f301458933f3 204 SUPERFAMILY SSF46955 50 130 3.3E-14 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS28185 cc449fb287d94b38db41f301458933f3 204 Gene3D G3DSA:1.10.1660.10 52 121 1.5E-13 T 06-07-2017 SMD11_RS28185 cc449fb287d94b38db41f301458933f3 204 Pfam PF13411 MerR HTH family regulatory protein 50 116 4.0E-14 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS28185 cc449fb287d94b38db41f301458933f3 204 SMART SM00422 46 118 1.2E-17 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS33265 d51870d5367c5d41cfb49da61a70f195 359 Gene3D G3DSA:3.40.50.300 8 238 2.1E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS33265 d51870d5367c5d41cfb49da61a70f195 359 SUPERFAMILY SSF52540 8 235 3.0E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS33265 d51870d5367c5d41cfb49da61a70f195 359 Pfam PF00005 ABC transporter 28 172 1.9E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS33265 d51870d5367c5d41cfb49da61a70f195 359 SMART SM00382 37 236 2.4E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS17155 bc46de3d0c0fe5c55c09e520be3668bc 505 Gene3D G3DSA:3.40.50.720 5 191 3.0E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17155 bc46de3d0c0fe5c55c09e520be3668bc 505 SUPERFAMILY SSF48179 189 298 8.33E-29 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS17155 bc46de3d0c0fe5c55c09e520be3668bc 505 SUPERFAMILY SSF48179 417 499 2.38E-15 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS17155 bc46de3d0c0fe5c55c09e520be3668bc 505 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 418 499 8.0E-15 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS17155 bc46de3d0c0fe5c55c09e520be3668bc 505 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 287 1.2E-28 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS17155 bc46de3d0c0fe5c55c09e520be3668bc 505 SUPERFAMILY SSF51735 8 189 1.6E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17155 bc46de3d0c0fe5c55c09e520be3668bc 505 Gene3D G3DSA:1.10.1040.10 418 492 3.3E-16 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS17155 bc46de3d0c0fe5c55c09e520be3668bc 505 Gene3D G3DSA:1.10.1040.10 192 287 2.8E-28 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS17155 bc46de3d0c0fe5c55c09e520be3668bc 505 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 187 1.6E-58 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS14920 8840832228427d904c6acca9a2a8bfff 197 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 118 129 - T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD11_RS14920 8840832228427d904c6acca9a2a8bfff 197 SUPERFAMILY SSF55083 31 174 3.01E-50 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD11_RS14920 8840832228427d904c6acca9a2a8bfff 197 Gene3D G3DSA:3.30.70.560 31 180 2.8E-56 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD11_RS14920 8840832228427d904c6acca9a2a8bfff 197 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 32 163 1.5E-44 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD11_RS14920 8840832228427d904c6acca9a2a8bfff 197 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 33 163 5.2E-38 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD11_RS00990 412de7086b728e54e44bf64a9bb195ac 207 SUPERFAMILY SSF46689 7 83 1.39E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS00990 412de7086b728e54e44bf64a9bb195ac 207 SUPERFAMILY SSF48498 83 180 7.12E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS00990 412de7086b728e54e44bf64a9bb195ac 207 Gene3D G3DSA:1.10.10.60 8 59 4.8E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS00990 412de7086b728e54e44bf64a9bb195ac 207 Gene3D G3DSA:1.10.357.10 60 179 1.9E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS00990 412de7086b728e54e44bf64a9bb195ac 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 2.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00990 412de7086b728e54e44bf64a9bb195ac 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 2.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00990 412de7086b728e54e44bf64a9bb195ac 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 2.1E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS03910 6bb866c3d09b695e232c1de0bb4c6d1a 548 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 396 415 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD11_RS03910 6bb866c3d09b695e232c1de0bb4c6d1a 548 SUPERFAMILY SSF56645 58 290 1.3E-37 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS03910 6bb866c3d09b695e232c1de0bb4c6d1a 548 Gene3D G3DSA:2.40.110.10 177 268 2.8E-22 T 06-07-2017 SMD11_RS03910 6bb866c3d09b695e232c1de0bb4c6d1a 548 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 281 437 4.6E-29 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS03910 6bb866c3d09b695e232c1de0bb4c6d1a 548 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 177 270 1.7E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS03910 6bb866c3d09b695e232c1de0bb4c6d1a 548 Gene3D G3DSA:1.20.140.10 269 441 4.1E-38 T 06-07-2017 SMD11_RS03910 6bb866c3d09b695e232c1de0bb4c6d1a 548 SUPERFAMILY SSF47203 286 440 2.74E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS19395 75c3253113b95f70948fb4dd66ff736d 410 Gene3D G3DSA:2.40.110.10 165 243 1.0E-5 T 06-07-2017 SMD11_RS19395 75c3253113b95f70948fb4dd66ff736d 410 SUPERFAMILY SSF47203 262 393 2.9E-32 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS19395 75c3253113b95f70948fb4dd66ff736d 410 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 263 386 9.0E-24 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS19395 75c3253113b95f70948fb4dd66ff736d 410 SUPERFAMILY SSF56645 5 246 7.72E-31 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS19395 75c3253113b95f70948fb4dd66ff736d 410 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 7.5E-22 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS19395 75c3253113b95f70948fb4dd66ff736d 410 Gene3D G3DSA:1.20.140.10 263 385 9.2E-31 T 06-07-2017 SMD11_RS19395 75c3253113b95f70948fb4dd66ff736d 410 Gene3D G3DSA:1.10.540.10 5 120 7.7E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 648 785 6.4E-19 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 Pfam PF04324 BFD-like [2Fe-2S] binding domain 438 488 1.1E-12 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 Gene3D G3DSA:3.50.50.60 3 124 2.3E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 817 0.0 T 06-07-2017 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 695 711 - T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 121 139 8.4E-13 T 06-07-2017 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 280 302 8.4E-13 T 06-07-2017 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 8.4E-13 T 06-07-2017 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 8.4E-13 T 06-07-2017 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 PRINTS PR00397 Sirohaem Fe-binding site signature 695 713 8.8E-6 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 PRINTS PR00397 Sirohaem Fe-binding site signature 652 670 8.8E-6 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 Gene3D G3DSA:3.50.50.60 125 329 2.9E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 Gene3D G3DSA:3.30.413.10 648 785 3.4E-33 T 06-07-2017 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 44 310 5.0E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 SUPERFAMILY SSF51905 47 329 5.76E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 576 637 2.1E-8 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 PIRSF PIRSF037149 1 851 0.0 T 06-07-2017 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 SUPERFAMILY SSF56014 649 822 7.85E-49 T 06-07-2017 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 SUPERFAMILY SSF55124 520 657 1.57E-22 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 191 1.3E-5 T 06-07-2017 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 295 302 1.3E-5 T 06-07-2017 SMD11_RS29320 60b656bd32937223811a9f1a579c8d2a 863 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 124 133 1.3E-5 T 06-07-2017 SMD11_RS31090 4899c2c219f1e5638ef2c558578369cc 342 Gene3D G3DSA:3.40.50.10490 36 153 8.7E-17 T 06-07-2017 SMD11_RS31090 4899c2c219f1e5638ef2c558578369cc 342 Pfam PF01380 SIS domain 44 141 4.8E-10 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 SMD11_RS31090 4899c2c219f1e5638ef2c558578369cc 342 SUPERFAMILY SSF53697 26 341 7.01E-52 T 06-07-2017 SMD11_RS31090 4899c2c219f1e5638ef2c558578369cc 342 Gene3D G3DSA:3.40.50.10490 180 332 2.6E-9 T 06-07-2017 SMD11_RS13610 86c8e954ebba56bc7e48a8356f767b38 202 Gene3D G3DSA:1.10.357.10 6 200 4.8E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS13610 86c8e954ebba56bc7e48a8356f767b38 202 SUPERFAMILY SSF46689 8 85 1.41E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS13610 86c8e954ebba56bc7e48a8356f767b38 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 4.5E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS13610 86c8e954ebba56bc7e48a8356f767b38 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 9.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS13610 86c8e954ebba56bc7e48a8356f767b38 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 9.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS12020 191e695ffbdb1eee7612d785f2f11333 312 SUPERFAMILY SSF161098 107 293 1.44E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS12020 191e695ffbdb1eee7612d785f2f11333 312 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 29 82 2.7E-6 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD11_RS12020 191e695ffbdb1eee7612d785f2f11333 312 Gene3D G3DSA:1.10.3720.10 105 309 1.6E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS12020 191e695ffbdb1eee7612d785f2f11333 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 312 7.5E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS04865 5e61d6cab7020b5bbcb967de553ed9c7 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS04865 5e61d6cab7020b5bbcb967de553ed9c7 223 SUPERFAMILY SSF46894 143 217 5.78E-22 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS04865 5e61d6cab7020b5bbcb967de553ed9c7 223 SMART SM00448 8 122 1.0E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS04865 5e61d6cab7020b5bbcb967de553ed9c7 223 SMART SM00421 154 211 2.3E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS04865 5e61d6cab7020b5bbcb967de553ed9c7 223 Pfam PF00072 Response regulator receiver domain 11 122 2.0E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS04865 5e61d6cab7020b5bbcb967de553ed9c7 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 2.8E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS04865 5e61d6cab7020b5bbcb967de553ed9c7 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 2.8E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS04865 5e61d6cab7020b5bbcb967de553ed9c7 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 2.8E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS04865 5e61d6cab7020b5bbcb967de553ed9c7 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 211 4.0E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS04865 5e61d6cab7020b5bbcb967de553ed9c7 223 Gene3D G3DSA:1.10.10.10 125 217 2.5E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04865 5e61d6cab7020b5bbcb967de553ed9c7 223 SUPERFAMILY SSF52172 7 131 1.42E-30 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS04865 5e61d6cab7020b5bbcb967de553ed9c7 223 Gene3D G3DSA:3.40.50.2300 7 124 4.7E-33 T 06-07-2017 SMD11_RS05080 3978df86c677f53aef96b52de8d6b36f 266 SUPERFAMILY SSF56770 7 224 2.49E-42 T 06-07-2017 SMD11_RS05080 3978df86c677f53aef96b52de8d6b36f 266 Gene3D G3DSA:3.40.50.700 8 170 2.4E-23 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS05080 3978df86c677f53aef96b52de8d6b36f 266 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 19 155 1.2E-22 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS26420 bbc5e6cd0fe66a5dc8bf3f01bb744f9f 260 ProSitePatterns PS00221 MIP family signature. 64 72 - T 06-07-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26420 bbc5e6cd0fe66a5dc8bf3f01bb744f9f 260 Pfam PF00230 Major intrinsic protein 7 255 4.5E-41 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26420 bbc5e6cd0fe66a5dc8bf3f01bb744f9f 260 Gene3D G3DSA:1.20.1080.10 6 258 6.4E-79 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMD11_RS26420 bbc5e6cd0fe66a5dc8bf3f01bb744f9f 260 SUPERFAMILY SSF81338 7 259 2.09E-61 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMD11_RS26420 bbc5e6cd0fe66a5dc8bf3f01bb744f9f 260 PRINTS PR00783 Major intrinsic protein family signature 83 102 9.6E-35 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26420 bbc5e6cd0fe66a5dc8bf3f01bb744f9f 260 PRINTS PR00783 Major intrinsic protein family signature 192 214 9.6E-35 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26420 bbc5e6cd0fe66a5dc8bf3f01bb744f9f 260 PRINTS PR00783 Major intrinsic protein family signature 46 70 9.6E-35 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26420 bbc5e6cd0fe66a5dc8bf3f01bb744f9f 260 PRINTS PR00783 Major intrinsic protein family signature 160 178 9.6E-35 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26420 bbc5e6cd0fe66a5dc8bf3f01bb744f9f 260 PRINTS PR00783 Major intrinsic protein family signature 239 259 9.6E-35 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26420 bbc5e6cd0fe66a5dc8bf3f01bb744f9f 260 PRINTS PR00783 Major intrinsic protein family signature 5 24 9.6E-35 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26790 febb51c9859826ee1e6aa97f211903d5 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 1.7E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS26790 febb51c9859826ee1e6aa97f211903d5 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 1.7E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS26790 febb51c9859826ee1e6aa97f211903d5 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 1.7E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS26790 febb51c9859826ee1e6aa97f211903d5 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 1.7E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS26790 febb51c9859826ee1e6aa97f211903d5 165 SUPERFAMILY SSF46785 10 161 7.61E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26790 febb51c9859826ee1e6aa97f211903d5 165 SMART SM00347 43 146 7.2E-24 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS26790 febb51c9859826ee1e6aa97f211903d5 165 Pfam PF12802 MarR family 48 110 8.9E-14 T 06-07-2017 SMD11_RS26790 febb51c9859826ee1e6aa97f211903d5 165 Gene3D G3DSA:1.10.10.10 9 162 3.1E-40 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04065 06fc266cc8e69457d9e250ba69789d24 538 SUPERFAMILY SSF53474 123 178 4.44E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04065 06fc266cc8e69457d9e250ba69789d24 538 SUPERFAMILY SSF53474 218 383 4.44E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04065 06fc266cc8e69457d9e250ba69789d24 538 SUPERFAMILY SSF53474 453 502 4.44E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04065 06fc266cc8e69457d9e250ba69789d24 538 Pfam PF00561 alpha/beta hydrolase fold 134 495 5.1E-25 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS04065 06fc266cc8e69457d9e250ba69789d24 538 Gene3D G3DSA:3.40.50.1820 400 518 1.4E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04065 06fc266cc8e69457d9e250ba69789d24 538 Gene3D G3DSA:3.40.50.1820 227 350 1.4E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04065 06fc266cc8e69457d9e250ba69789d24 538 Gene3D G3DSA:3.40.50.1820 97 183 1.4E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS26235 5478ae0f7f5651033fbc91363d20924b 443 PIRSF PIRSF036794 18 443 1.7E-132 T 06-07-2017 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type SMD11_RS26235 5478ae0f7f5651033fbc91363d20924b 443 SUPERFAMILY SSF159501 30 441 1.92E-105 T 06-07-2017 SMD11_RS26235 5478ae0f7f5651033fbc91363d20924b 443 Gene3D G3DSA:3.40.1660.10 306 440 1.0E-54 T 06-07-2017 SMD11_RS26235 5478ae0f7f5651033fbc91363d20924b 443 Gene3D G3DSA:3.40.1660.10 32 94 1.0E-54 T 06-07-2017 SMD11_RS26235 5478ae0f7f5651033fbc91363d20924b 443 Gene3D G3DSA:3.30.1870.10 95 168 3.2E-24 T 06-07-2017 SMD11_RS26235 5478ae0f7f5651033fbc91363d20924b 443 Gene3D G3DSA:1.20.1440.30 172 304 2.1E-30 T 06-07-2017 SMD11_RS26235 5478ae0f7f5651033fbc91363d20924b 443 Pfam PF05139 Erythromycin esterase 93 435 2.9E-75 T 06-07-2017 IPR007815 Erythromycin esterase GO:0046677 SMD11_RS23815 82e724275b63efaa4d8b97f2371e7705 406 Pfam PF07690 Major Facilitator Superfamily 9 339 1.5E-42 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS23815 82e724275b63efaa4d8b97f2371e7705 406 SUPERFAMILY SSF103473 3 373 1.83E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS23815 82e724275b63efaa4d8b97f2371e7705 406 Gene3D G3DSA:1.20.1250.20 199 372 3.9E-14 T 06-07-2017 SMD11_RS23815 82e724275b63efaa4d8b97f2371e7705 406 Gene3D G3DSA:1.20.1250.20 5 186 5.5E-28 T 06-07-2017 SMD11_RS02645 676aed0eb99d7b13486b54c1ed70f546 380 SUPERFAMILY SSF55486 139 241 3.04E-6 T 06-07-2017 SMD11_RS02645 676aed0eb99d7b13486b54c1ed70f546 380 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 83 319 1.5E-38 T 06-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMD11_RS02645 676aed0eb99d7b13486b54c1ed70f546 380 Gene3D G3DSA:3.40.390.10 165 238 2.6E-6 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD11_RS26840 3b727440c306f19e854a2d82936ef892 241 Gene3D G3DSA:1.20.910.10 71 232 2.9E-13 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS26840 3b727440c306f19e854a2d82936ef892 241 SUPERFAMILY SSF48613 64 226 1.07E-15 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS11865 594cd2ec0d49a1161479855c440ed922 256 Pfam PF03641 Possible lysine decarboxylase 120 247 6.6E-34 T 06-07-2017 IPR031100 LOG family SMD11_RS11865 594cd2ec0d49a1161479855c440ed922 256 SUPERFAMILY SSF102405 48 249 2.9E-63 T 06-07-2017 SMD11_RS11865 594cd2ec0d49a1161479855c440ed922 256 Gene3D G3DSA:3.40.50.450 59 252 1.5E-63 T 06-07-2017 SMD11_RS11865 594cd2ec0d49a1161479855c440ed922 256 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 78 250 2.8E-43 T 06-07-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG SMD11_RS30335 83c920ffa4664570c570fcf054038211 221 SUPERFAMILY SSF54593 76 213 3.66E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS30335 83c920ffa4664570c570fcf054038211 221 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 81 213 4.0E-6 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS30335 83c920ffa4664570c570fcf054038211 221 Gene3D G3DSA:3.10.180.10 85 215 6.5E-19 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS20980 5707d02f8de0bf867079876f04ace770 198 SUPERFAMILY SSF160904 9 192 2.62E-46 T 06-07-2017 SMD11_RS20980 5707d02f8de0bf867079876f04ace770 198 Pfam PF07336 Putative stress-induced transcription regulator 14 145 1.8E-26 T 06-07-2017 IPR010852 Putative stress-induced transcription regulator SMD11_RS20980 5707d02f8de0bf867079876f04ace770 198 Pfam PF11706 CGNR zinc finger 150 192 1.2E-17 T 06-07-2017 IPR021005 Zinc finger, CGNR SMD11_RS20980 5707d02f8de0bf867079876f04ace770 198 Gene3D G3DSA:1.10.3300.10 9 192 1.3E-51 T 06-07-2017 IPR023286 ABATE domain SMD11_RS00920 fc92ea883a7e07b0c6a4f3ee887b5985 193 Pfam PF01947 Protein of unknown function (DUF98) 31 176 1.5E-4 T 06-07-2017 IPR002800 Protein of unknown function DUF98 SMD11_RS00920 fc92ea883a7e07b0c6a4f3ee887b5985 193 Gene3D G3DSA:3.40.1410.10 24 177 1.9E-17 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS00920 fc92ea883a7e07b0c6a4f3ee887b5985 193 SUPERFAMILY SSF64288 24 176 6.28E-16 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS20970 c6b46af2ced76d65b6897526dc8631e8 445 SUPERFAMILY SSF103473 56 430 9.42E-20 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS20970 c6b46af2ced76d65b6897526dc8631e8 445 Gene3D G3DSA:1.20.1250.20 56 237 8.0E-5 T 06-07-2017 SMD11_RS20970 c6b46af2ced76d65b6897526dc8631e8 445 Gene3D G3DSA:1.20.1250.20 254 428 3.5E-4 T 06-07-2017 SMD11_RS20970 c6b46af2ced76d65b6897526dc8631e8 445 Pfam PF07690 Major Facilitator Superfamily 63 375 2.9E-10 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS03190 177c3514038f78c13f930e56d639f4fb 461 SUPERFAMILY SSF53187 14 207 1.57E-54 T 06-07-2017 SMD11_RS03190 177c3514038f78c13f930e56d639f4fb 461 SUPERFAMILY SSF53187 369 457 1.57E-54 T 06-07-2017 SMD11_RS03190 177c3514038f78c13f930e56d639f4fb 461 Pfam PF01546 Peptidase family M20/M25/M40 94 445 8.5E-35 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD11_RS03190 177c3514038f78c13f930e56d639f4fb 461 Gene3D G3DSA:3.40.630.10 368 457 1.1E-60 T 06-07-2017 SMD11_RS03190 177c3514038f78c13f930e56d639f4fb 461 Gene3D G3DSA:3.40.630.10 14 201 1.1E-60 T 06-07-2017 SMD11_RS03190 177c3514038f78c13f930e56d639f4fb 461 Gene3D G3DSA:3.30.70.360 207 364 3.9E-34 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS03190 177c3514038f78c13f930e56d639f4fb 461 Pfam PF07687 Peptidase dimerisation domain 212 355 1.6E-11 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS23010 707509060c31052d8928b899f515aa62 237 Pfam PF02698 DUF218 domain 65 184 2.4E-24 T 06-07-2017 IPR003848 Domain of unknown function DUF218 SMD11_RS23010 707509060c31052d8928b899f515aa62 237 Gene3D G3DSA:3.40.50.620 61 184 2.7E-11 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS24750 d0fe9930494e1d97c52df6f6f3d143c6 269 Gene3D G3DSA:3.20.20.70 2 259 4.3E-96 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS24750 d0fe9930494e1d97c52df6f6f3d143c6 269 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 68 - T 06-07-2017 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 SMD11_RS24750 d0fe9930494e1d97c52df6f6f3d143c6 269 SUPERFAMILY SSF51366 12 257 1.18E-78 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMD11_RS24750 d0fe9930494e1d97c52df6f6f3d143c6 269 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 34 253 29.798 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 SMD11_RS24750 d0fe9930494e1d97c52df6f6f3d143c6 269 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 255 1.4E-80 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 SMD11_RS24750 d0fe9930494e1d97c52df6f6f3d143c6 269 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 257 33.998 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 SMD11_RS25855 98e3f76bb345c1bc82e47894df8f225a 361 Gene3D G3DSA:3.40.50.720 4 171 2.1E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS25855 98e3f76bb345c1bc82e47894df8f225a 361 SUPERFAMILY SSF48179 165 253 4.76E-21 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS25855 98e3f76bb345c1bc82e47894df8f225a 361 Gene3D G3DSA:3.30.70.260 295 356 5.8E-4 T 06-07-2017 SMD11_RS25855 98e3f76bb345c1bc82e47894df8f225a 361 Pfam PF02153 Prephenate dehydrogenase 18 250 2.9E-57 T 06-07-2017 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 SMD11_RS25855 98e3f76bb345c1bc82e47894df8f225a 361 SUPERFAMILY SSF55021 294 354 3.12E-5 T 06-07-2017 SMD11_RS25855 98e3f76bb345c1bc82e47894df8f225a 361 SUPERFAMILY SSF51735 5 158 5.23E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS07490 37e6e2e6d46ca4aa2180665b62d3ec06 422 PRINTS PR01758 Capsule biosynthesis protein CapB signature 366 382 3.7E-32 T 06-07-2017 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD11_RS07490 37e6e2e6d46ca4aa2180665b62d3ec06 422 PRINTS PR01758 Capsule biosynthesis protein CapB signature 262 279 3.7E-32 T 06-07-2017 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD11_RS07490 37e6e2e6d46ca4aa2180665b62d3ec06 422 PRINTS PR01758 Capsule biosynthesis protein CapB signature 38 54 3.7E-32 T 06-07-2017 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD11_RS07490 37e6e2e6d46ca4aa2180665b62d3ec06 422 PRINTS PR01758 Capsule biosynthesis protein CapB signature 143 158 3.7E-32 T 06-07-2017 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD11_RS07490 37e6e2e6d46ca4aa2180665b62d3ec06 422 PRINTS PR01758 Capsule biosynthesis protein CapB signature 199 216 3.7E-32 T 06-07-2017 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD11_RS07490 37e6e2e6d46ca4aa2180665b62d3ec06 422 PRINTS PR01758 Capsule biosynthesis protein CapB signature 114 129 3.7E-32 T 06-07-2017 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD11_RS07490 37e6e2e6d46ca4aa2180665b62d3ec06 422 PRINTS PR01758 Capsule biosynthesis protein CapB signature 61 78 3.7E-32 T 06-07-2017 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD11_RS07490 37e6e2e6d46ca4aa2180665b62d3ec06 422 PRINTS PR01758 Capsule biosynthesis protein CapB signature 297 312 3.7E-32 T 06-07-2017 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD11_RS07490 37e6e2e6d46ca4aa2180665b62d3ec06 422 Pfam PF08245 Mur ligase middle domain 41 201 3.1E-5 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS07490 37e6e2e6d46ca4aa2180665b62d3ec06 422 Gene3D G3DSA:3.40.1190.10 37 240 9.9E-10 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS07490 37e6e2e6d46ca4aa2180665b62d3ec06 422 SUPERFAMILY SSF53623 35 241 3.82E-11 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS07490 37e6e2e6d46ca4aa2180665b62d3ec06 422 TIGRFAM TIGR04012 poly_gGlu_PgsB: poly-gamma-glutamate synthase PgsB 7 386 5.6E-111 T 06-07-2017 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 SMD11_RS06845 bc18a02de35651ead04bb91257b80be7 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 58 335 1.1E-53 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD11_RS10100 ad2e3eb0e326dd97f40b2c099ccdb2fa 739 Pfam PF03176 MMPL family 44 365 3.2E-64 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 SMD11_RS10100 ad2e3eb0e326dd97f40b2c099ccdb2fa 739 Pfam PF03176 MMPL family 437 695 3.1E-27 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 SMD11_RS10100 ad2e3eb0e326dd97f40b2c099ccdb2fa 739 Gene3D G3DSA:1.20.1640.10 475 700 2.5E-26 T 06-07-2017 SMD11_RS10100 ad2e3eb0e326dd97f40b2c099ccdb2fa 739 Gene3D G3DSA:1.20.1640.10 138 337 7.0E-28 T 06-07-2017 SMD11_RS10100 ad2e3eb0e326dd97f40b2c099ccdb2fa 739 SUPERFAMILY SSF82866 464 695 4.32E-23 T 06-07-2017 SMD11_RS10100 ad2e3eb0e326dd97f40b2c099ccdb2fa 739 SUPERFAMILY SSF82866 120 330 1.57E-30 T 06-07-2017 SMD11_RS28655 a5a1f64ba4f391554f2ea89c25a6e4a2 561 Pfam PF05960 Bacterial protein of unknown function (DUF885) 26 557 6.1E-144 T 06-07-2017 IPR010281 Protein of unknown function DUF885 SMD11_RS11375 1713bd56cf02cee5e24d70c56bc2c31f 328 Gene3D G3DSA:1.25.40.10 21 110 9.8E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS11375 1713bd56cf02cee5e24d70c56bc2c31f 328 SUPERFAMILY SSF48452 19 109 1.21E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS33845 0cccf2a8d046ca6b8b168844eeec790f 208 Gene3D G3DSA:3.40.50.1240 3 198 1.4E-54 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS33845 0cccf2a8d046ca6b8b168844eeec790f 208 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 198 9.4E-57 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS33845 0cccf2a8d046ca6b8b168844eeec790f 208 SUPERFAMILY SSF53254 3 197 4.02E-56 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS33845 0cccf2a8d046ca6b8b168844eeec790f 208 SMART SM00855 3 157 3.5E-19 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS11390 df30f33cec91ff3c0099913baa9726a0 111 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 10 84 2.3E-30 T 06-07-2017 IPR024020 Anti sigma-R factor, mycothiol system,RsrA SMD11_RS11390 df30f33cec91ff3c0099913baa9726a0 111 Pfam PF13490 Putative zinc-finger 11 44 3.2E-9 T 06-07-2017 IPR027383 Putative zinc-finger SMD11_RS11390 df30f33cec91ff3c0099913baa9726a0 111 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 4 85 8.1E-36 T 06-07-2017 IPR014295 Anti-sigma factor SMD11_RS01305 735d2e45ddbe5077fe2cfcd860fb3bec 337 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 109 189 1.9E-25 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS01305 735d2e45ddbe5077fe2cfcd860fb3bec 337 Gene3D G3DSA:3.40.47.10 7 162 3.9E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS01305 735d2e45ddbe5077fe2cfcd860fb3bec 337 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 243 330 7.4E-24 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS01305 735d2e45ddbe5077fe2cfcd860fb3bec 337 Gene3D G3DSA:3.40.47.10 163 332 1.6E-35 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS01305 735d2e45ddbe5077fe2cfcd860fb3bec 337 SUPERFAMILY SSF53901 10 331 2.08E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32690 07c53bdfdb2c5d4ad20db25ee6d695d3 558 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 21 220 4.8E-14 T 06-07-2017 SMD11_RS32690 07c53bdfdb2c5d4ad20db25ee6d695d3 558 SUPERFAMILY SSF51905 17 249 2.0E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS32690 07c53bdfdb2c5d4ad20db25ee6d695d3 558 SUPERFAMILY SSF51905 325 543 1.17E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS32690 07c53bdfdb2c5d4ad20db25ee6d695d3 558 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 3.2E-7 T 06-07-2017 SMD11_RS32690 07c53bdfdb2c5d4ad20db25ee6d695d3 558 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 189 214 3.2E-7 T 06-07-2017 SMD11_RS32690 07c53bdfdb2c5d4ad20db25ee6d695d3 558 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 19 41 3.2E-7 T 06-07-2017 SMD11_RS32690 07c53bdfdb2c5d4ad20db25ee6d695d3 558 Gene3D G3DSA:3.50.50.60 5 229 4.7E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS32690 07c53bdfdb2c5d4ad20db25ee6d695d3 558 Gene3D G3DSA:3.50.50.60 360 540 6.0E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS11120 ca3a58faead66788b8883fc4dfa6e452 131 TIGRFAM TIGR02753 sodN: superoxide dismutase, Ni 1 131 3.5E-52 T 06-07-2017 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 SMD11_RS11120 ca3a58faead66788b8883fc4dfa6e452 131 Pfam PF09055 Nickel-containing superoxide dismutase 11 129 1.7E-41 T 06-07-2017 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 SMD11_RS11120 ca3a58faead66788b8883fc4dfa6e452 131 SUPERFAMILY SSF109770 15 131 5.62E-51 T 06-07-2017 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 SMD11_RS11120 ca3a58faead66788b8883fc4dfa6e452 131 Gene3D G3DSA:1.20.120.400 15 130 2.9E-48 T 06-07-2017 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 SMD11_RS10230 f55ff10645e8ba700b087fbbdf844327 196 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 16 194 5.0E-48 T 06-07-2017 IPR017520 Conserved hypothetical protein CHP03086 SMD11_RS10230 f55ff10645e8ba700b087fbbdf844327 196 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 15 194 1.0E-22 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD11_RS10230 f55ff10645e8ba700b087fbbdf844327 196 SUPERFAMILY SSF109854 7 141 2.15E-15 T 06-07-2017 SMD11_RS10230 f55ff10645e8ba700b087fbbdf844327 196 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 16 135 5.1E-8 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD11_RS20075 87176f43df5b1da6efb7430253d8c005 291 SUPERFAMILY SSF53335 28 287 7.98E-64 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS20075 87176f43df5b1da6efb7430253d8c005 291 Pfam PF00398 Ribosomal RNA adenine dimethylase 32 287 6.5E-43 T 06-07-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm SMD11_RS20075 87176f43df5b1da6efb7430253d8c005 291 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 60 87 - T 06-07-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 SMD11_RS20075 87176f43df5b1da6efb7430253d8c005 291 SMART SM00650 44 218 1.4E-70 T 06-07-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 SMD11_RS20075 87176f43df5b1da6efb7430253d8c005 291 Gene3D G3DSA:3.40.50.150 16 219 5.5E-67 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS20075 87176f43df5b1da6efb7430253d8c005 291 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 28 287 3.8E-71 T 06-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 SMD11_RS20075 87176f43df5b1da6efb7430253d8c005 291 Gene3D G3DSA:1.10.8.100 226 287 3.0E-21 T 06-07-2017 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 SMD11_RS20075 87176f43df5b1da6efb7430253d8c005 291 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 28 290 48.765 T 06-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 SMD11_RS31055 a5373e196083591687a7eb448e81a1a6 302 Pfam PF00296 Luciferase-like monooxygenase 4 234 6.1E-45 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS31055 a5373e196083591687a7eb448e81a1a6 302 SUPERFAMILY SSF51679 1 238 4.84E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS31055 a5373e196083591687a7eb448e81a1a6 302 Gene3D G3DSA:3.20.20.30 1 245 1.4E-61 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS30695 512de7874e79466690433ffdce1bccfa 688 Gene3D G3DSA:1.10.3470.10 364 688 1.1E-88 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS30695 512de7874e79466690433ffdce1bccfa 688 SUPERFAMILY SSF81345 22 346 2.22E-53 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS30695 512de7874e79466690433ffdce1bccfa 688 Pfam PF01032 FecCD transport family 379 685 8.3E-84 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD11_RS30695 512de7874e79466690433ffdce1bccfa 688 Pfam PF01032 FecCD transport family 32 345 1.4E-63 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD11_RS30695 512de7874e79466690433ffdce1bccfa 688 SUPERFAMILY SSF81345 358 685 2.09E-74 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS30695 512de7874e79466690433ffdce1bccfa 688 Gene3D G3DSA:1.10.3470.10 21 348 1.3E-70 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS23285 9cc36621bc235a434040f4a147199300 191 Pfam PF02342 TerD domain 1 186 2.5E-81 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS23285 9cc36621bc235a434040f4a147199300 191 Gene3D G3DSA:2.60.60.30 18 183 3.8E-71 T 06-07-2017 SMD11_RS05785 7e327a1a50c7ae54a055387098efc79a 610 Pfam PF00501 AMP-binding enzyme 23 477 3.8E-86 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS05785 7e327a1a50c7ae54a055387098efc79a 610 Gene3D G3DSA:3.30.300.30 475 597 5.4E-5 T 06-07-2017 SMD11_RS05785 7e327a1a50c7ae54a055387098efc79a 610 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS05785 7e327a1a50c7ae54a055387098efc79a 610 Gene3D G3DSA:3.40.50.980 345 407 1.8E-25 T 06-07-2017 SMD11_RS05785 7e327a1a50c7ae54a055387098efc79a 610 Gene3D G3DSA:3.40.50.980 191 289 1.8E-25 T 06-07-2017 SMD11_RS05785 7e327a1a50c7ae54a055387098efc79a 610 Gene3D G3DSA:2.30.38.10 408 468 5.8E-19 T 06-07-2017 SMD11_RS05785 7e327a1a50c7ae54a055387098efc79a 610 SUPERFAMILY SSF56801 17 294 1.14E-107 T 06-07-2017 SMD11_RS05785 7e327a1a50c7ae54a055387098efc79a 610 SUPERFAMILY SSF56801 348 606 1.14E-107 T 06-07-2017 SMD11_RS05785 7e327a1a50c7ae54a055387098efc79a 610 Gene3D G3DSA:3.40.50.980 20 190 1.2E-28 T 06-07-2017 SMD11_RS15990 bd249f63109309363904787309b16af7 529 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 185 200 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site SMD11_RS15990 bd249f63109309363904787309b16af7 529 Pfam PF00135 Carboxylesterase family 15 520 8.9E-80 T 06-07-2017 IPR002018 Carboxylesterase, type B SMD11_RS15990 bd249f63109309363904787309b16af7 529 Gene3D G3DSA:3.40.50.1820 10 522 1.7E-112 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15990 bd249f63109309363904787309b16af7 529 SUPERFAMILY SSF53474 12 522 1.41E-92 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS29990 d5a0e4700ed463b7052ed594c957b8fc 70 SUPERFAMILY SSF160582 2 67 4.18E-29 T 06-07-2017 SMD11_RS29990 d5a0e4700ed463b7052ed594c957b8fc 70 Pfam PF03621 MbtH-like protein 2 51 1.5E-26 T 06-07-2017 IPR005153 MbtH-like protein SMD11_RS29990 d5a0e4700ed463b7052ed594c957b8fc 70 SMART SM00923 2 52 1.2E-31 T 06-07-2017 IPR005153 MbtH-like protein SMD11_RS29990 d5a0e4700ed463b7052ed594c957b8fc 70 Gene3D G3DSA:3.90.820.10 10 67 2.4E-29 T 06-07-2017 SMD11_RS20585 dcbda8e58fd331e0586dea29d897c577 175 Pfam PF00731 AIR carboxylase 7 152 1.1E-64 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMD11_RS20585 dcbda8e58fd331e0586dea29d897c577 175 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 7 158 32.135 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMD11_RS20585 dcbda8e58fd331e0586dea29d897c577 175 SUPERFAMILY SSF52255 5 163 1.27E-64 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMD11_RS20585 dcbda8e58fd331e0586dea29d897c577 175 PIRSF PIRSF001338 2 165 1.8E-67 T 06-07-2017 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 SMD11_RS20585 dcbda8e58fd331e0586dea29d897c577 175 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 7 161 6.0E-63 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMD11_RS20585 dcbda8e58fd331e0586dea29d897c577 175 SMART SM01001 5 154 3.5E-94 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMD11_RS20585 dcbda8e58fd331e0586dea29d897c577 175 Gene3D G3DSA:3.40.50.7700 3 162 4.1E-73 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SMD11_RS10385 6c6ca3daa4481d5ce095344dceabecb8 664 Gene3D G3DSA:3.20.20.80 155 557 1.6E-63 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS10385 6c6ca3daa4481d5ce095344dceabecb8 664 Gene3D G3DSA:3.20.20.80 69 95 1.6E-63 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS10385 6c6ca3daa4481d5ce095344dceabecb8 664 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 1 654 45.722 T 06-07-2017 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 SMD11_RS10385 6c6ca3daa4481d5ce095344dceabecb8 664 SUPERFAMILY SSF51445 196 559 1.76E-79 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS10385 6c6ca3daa4481d5ce095344dceabecb8 664 Gene3D G3DSA:2.60.40.1180 563 640 1.4E-10 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta SMD11_RS10385 6c6ca3daa4481d5ce095344dceabecb8 664 SUPERFAMILY SSF51011 564 640 3.84E-5 T 06-07-2017 SMD11_RS10385 6c6ca3daa4481d5ce095344dceabecb8 664 SMART SM00642 196 527 0.0025 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS10385 6c6ca3daa4481d5ce095344dceabecb8 664 Pfam PF11896 Domain of unknown function (DUF3416) 3 190 1.4E-58 T 06-07-2017 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 SMD11_RS20375 b59854a697d953a53709439d0d9458ef 487 Gene3D G3DSA:3.40.605.10 7 269 8.3E-109 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS20375 b59854a697d953a53709439d0d9458ef 487 Pfam PF00171 Aldehyde dehydrogenase family 16 481 2.5E-181 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS20375 b59854a697d953a53709439d0d9458ef 487 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS20375 b59854a697d953a53709439d0d9458ef 487 Gene3D G3DSA:3.40.309.10 270 456 9.7E-72 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS20375 b59854a697d953a53709439d0d9458ef 487 SUPERFAMILY SSF53720 5 483 7.46E-177 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS14110 e8a55ef07215a276e2650f49d109a32e 238 Gene3D G3DSA:3.90.550.10 9 236 4.0E-53 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS14110 e8a55ef07215a276e2650f49d109a32e 238 Pfam PF00483 Nucleotidyl transferase 11 236 7.7E-24 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMD11_RS14110 e8a55ef07215a276e2650f49d109a32e 238 SUPERFAMILY SSF53448 9 236 2.93E-53 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 SMART SM00382 586 726 5.5E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 Gene3D G3DSA:3.40.50.300 550 737 2.2E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 SMART SM00722 313 474 4.4E-5 T 06-07-2017 IPR006633 Carbohydrate-binding/sugar hydrolysis domain SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 SMART SM00722 41 172 8.9 T 06-07-2017 IPR006633 Carbohydrate-binding/sugar hydrolysis domain SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 PRINTS PR00819 CbxX/CfqX superfamily signature 767 779 4.9E-48 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 PRINTS PR00819 CbxX/CfqX superfamily signature 641 660 4.9E-48 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 PRINTS PR00819 CbxX/CfqX superfamily signature 672 684 4.9E-48 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 PRINTS PR00819 CbxX/CfqX superfamily signature 589 604 4.9E-48 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 PRINTS PR00819 CbxX/CfqX superfamily signature 627 641 4.9E-48 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 PRINTS PR00819 CbxX/CfqX superfamily signature 549 563 4.9E-48 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 PRINTS PR00819 CbxX/CfqX superfamily signature 693 710 4.9E-48 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 PRINTS PR00819 CbxX/CfqX superfamily signature 710 729 4.9E-48 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 SUPERFAMILY SSF51126 344 476 3.88E-14 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 Gene3D G3DSA:2.160.20.10 5 256 2.5E-18 T 06-07-2017 IPR012334 Pectin lyase fold SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 Gene3D G3DSA:2.160.20.10 331 466 2.6E-8 T 06-07-2017 IPR012334 Pectin lyase fold SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 591 721 1.9E-16 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 SMART SM00710 221 243 1200.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 SMART SM00710 453 475 9200.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 SMART SM00710 362 383 3400.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 SMART SM00710 151 173 540.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 SMART SM00710 407 429 25.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 SMART SM00710 385 406 550.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 SMART SM00710 174 196 120.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 SMART SM00710 430 452 3.5 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 SMART SM00710 128 150 6.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 Pfam PF13229 Right handed beta helix region 310 461 5.5E-14 T 06-07-2017 SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 Pfam PF13229 Right handed beta helix region 121 265 3.6E-16 T 06-07-2017 SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 SUPERFAMILY SSF52540 550 786 2.12E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03120 8630b0be09a6d3cb6b255270a57aedd1 809 SUPERFAMILY SSF51126 20 258 2.84E-28 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor SMD11_RS10200 9765705b404a61a90af3dfcc54923a1e 869 Pfam PF12161 HsdM N-terminal domain 9 163 7.9E-21 T 06-07-2017 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain SMD11_RS10200 9765705b404a61a90af3dfcc54923a1e 869 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 199 215 9.6E-19 T 06-07-2017 SMD11_RS10200 9765705b404a61a90af3dfcc54923a1e 869 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 301 313 9.6E-19 T 06-07-2017 SMD11_RS10200 9765705b404a61a90af3dfcc54923a1e 869 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 223 237 9.6E-19 T 06-07-2017 SMD11_RS10200 9765705b404a61a90af3dfcc54923a1e 869 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 340 364 9.6E-19 T 06-07-2017 SMD11_RS10200 9765705b404a61a90af3dfcc54923a1e 869 Pfam PF02384 N-6 DNA Methylase 177 488 2.4E-92 T 06-07-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SMD11_RS10200 9765705b404a61a90af3dfcc54923a1e 869 Gene3D G3DSA:3.40.50.150 201 437 3.0E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS10200 9765705b404a61a90af3dfcc54923a1e 869 SUPERFAMILY SSF53335 78 531 5.05E-122 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS10200 9765705b404a61a90af3dfcc54923a1e 869 SUPERFAMILY SSF53335 8 46 5.05E-122 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS05095 ee1caf12d73c6c85e86f5298e96e6aa7 345 Gene3D G3DSA:3.90.650.10 167 316 6.2E-24 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain SMD11_RS05095 ee1caf12d73c6c85e86f5298e96e6aa7 345 Pfam PF02769 AIR synthase related protein, C-terminal domain 169 316 6.5E-25 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain SMD11_RS05095 ee1caf12d73c6c85e86f5298e96e6aa7 345 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 14 345 9.2E-123 T 06-07-2017 IPR011854 Hydrogenase expression/formation protein HypE SMD11_RS05095 ee1caf12d73c6c85e86f5298e96e6aa7 345 Pfam PF00586 AIR synthase related protein, N-terminal domain 47 156 4.4E-18 T 06-07-2017 IPR016188 PurM-like, N-terminal domain SMD11_RS05095 ee1caf12d73c6c85e86f5298e96e6aa7 345 SUPERFAMILY SSF56042 164 341 1.21E-41 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain SMD11_RS05095 ee1caf12d73c6c85e86f5298e96e6aa7 345 SUPERFAMILY SSF55326 14 157 1.69E-29 T 06-07-2017 SMD11_RS05095 ee1caf12d73c6c85e86f5298e96e6aa7 345 PIRSF PIRSF005644 10 345 2.1E-112 T 06-07-2017 IPR011854 Hydrogenase expression/formation protein HypE SMD11_RS05095 ee1caf12d73c6c85e86f5298e96e6aa7 345 Gene3D G3DSA:3.30.1330.10 37 157 5.9E-23 T 06-07-2017 IPR016188 PurM-like, N-terminal domain SMD11_RS02605 c567741b7219a23bec84a4292cc5479a 312 SUPERFAMILY SSF110857 7 120 5.62E-8 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like SMD11_RS02605 c567741b7219a23bec84a4292cc5479a 312 Gene3D G3DSA:3.10.490.10 7 115 2.5E-5 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like SMD11_RS02605 c567741b7219a23bec84a4292cc5479a 312 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 125 301 4.5E-18 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS02605 c567741b7219a23bec84a4292cc5479a 312 Gene3D G3DSA:3.40.50.1110 120 307 1.5E-28 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS02605 c567741b7219a23bec84a4292cc5479a 312 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 9 114 2.7E-10 T 06-07-2017 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like SMD11_RS02605 c567741b7219a23bec84a4292cc5479a 312 SUPERFAMILY SSF52266 119 307 5.33E-31 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS12965 d7078b6f2b9fc686f4b8ab261f20d7c1 522 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 20 31 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS12965 d7078b6f2b9fc686f4b8ab261f20d7c1 522 Pfam PF09334 tRNA synthetases class I (M) 21 384 6.1E-51 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS12965 d7078b6f2b9fc686f4b8ab261f20d7c1 522 SUPERFAMILY SSF52374 11 146 1.74E-52 T 06-07-2017 SMD11_RS12965 d7078b6f2b9fc686f4b8ab261f20d7c1 522 SUPERFAMILY SSF52374 177 382 1.74E-52 T 06-07-2017 SMD11_RS12965 d7078b6f2b9fc686f4b8ab261f20d7c1 522 Gene3D G3DSA:3.40.50.620 15 149 2.2E-43 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS12965 d7078b6f2b9fc686f4b8ab261f20d7c1 522 Gene3D G3DSA:3.40.50.620 184 383 2.2E-43 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS12965 d7078b6f2b9fc686f4b8ab261f20d7c1 522 Gene3D G3DSA:2.20.28.20 150 173 8.6E-4 T 06-07-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMD11_RS11260 3ccb8ff8e555947a49753baa81da013d 341 SUPERFAMILY SSF53697 2 339 1.11E-72 T 06-07-2017 SMD11_RS11260 3ccb8ff8e555947a49753baa81da013d 341 Gene3D G3DSA:3.40.50.10490 2 164 2.3E-28 T 06-07-2017 SMD11_RS11260 3ccb8ff8e555947a49753baa81da013d 341 Pfam PF01380 SIS domain 198 323 1.6E-15 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 SMD11_RS11260 3ccb8ff8e555947a49753baa81da013d 341 Pfam PF01380 SIS domain 39 161 8.3E-17 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 SMD11_RS11260 3ccb8ff8e555947a49753baa81da013d 341 Gene3D G3DSA:3.40.50.10490 173 339 1.9E-40 T 06-07-2017 SMD11_RS33310 a6522846d82e2ac256af33e43746eb59 192 Gene3D G3DSA:1.10.357.10 9 189 3.7E-36 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS33310 a6522846d82e2ac256af33e43746eb59 192 SUPERFAMILY SSF46689 10 80 4.69E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS33310 a6522846d82e2ac256af33e43746eb59 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 1.8E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS33310 a6522846d82e2ac256af33e43746eb59 192 SUPERFAMILY SSF48498 84 189 6.43E-12 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS03330 1453c407470b02eaa3f8cec523936986 165 SMART SM00903 1 148 1.6E-46 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS03330 1453c407470b02eaa3f8cec523936986 165 Pfam PF01613 Flavin reductase like domain 1 148 1.2E-34 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS03330 1453c407470b02eaa3f8cec523936986 165 Gene3D G3DSA:2.30.110.10 1 147 1.4E-46 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS03330 1453c407470b02eaa3f8cec523936986 165 SUPERFAMILY SSF50475 1 149 4.23E-41 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS18900 0343cc653d26462561b7c93c61c245a5 278 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 06-07-2017 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18900 0343cc653d26462561b7c93c61c245a5 278 SUPERFAMILY SSF50249 3 126 3.12E-48 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS18900 0343cc653d26462561b7c93c61c245a5 278 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.982 T 06-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18900 0343cc653d26462561b7c93c61c245a5 278 Gene3D G3DSA:4.10.950.10 197 273 2.2E-32 T 06-07-2017 IPR014726 Ribosomal protein L2, domain 3 SMD11_RS18900 0343cc653d26462561b7c93c61c245a5 278 PIRSF PIRSF002158 4 275 4.5E-96 T 06-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18900 0343cc653d26462561b7c93c61c245a5 278 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 7.1E-32 T 06-07-2017 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18900 0343cc653d26462561b7c93c61c245a5 278 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 4.8E-129 T 06-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18900 0343cc653d26462561b7c93c61c245a5 278 SUPERFAMILY SSF50104 127 271 1.5E-57 T 06-07-2017 IPR008991 Translation protein SH3-like domain SMD11_RS18900 0343cc653d26462561b7c93c61c245a5 278 SMART SM01383 42 119 4.1E-39 T 06-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18900 0343cc653d26462561b7c93c61c245a5 278 Gene3D G3DSA:2.40.50.140 1 115 6.9E-51 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS18900 0343cc653d26462561b7c93c61c245a5 278 SMART SM01382 125 253 9.9E-92 T 06-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 SMD11_RS18900 0343cc653d26462561b7c93c61c245a5 278 Gene3D G3DSA:2.30.30.30 120 196 5.2E-32 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 SMD11_RS18900 0343cc653d26462561b7c93c61c245a5 278 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 5.6E-57 T 06-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 SMD11_RS32540 784834bd537e77eb987307aed7a64a22 134 SUPERFAMILY SSF55729 11 127 8.68E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS32540 784834bd537e77eb987307aed7a64a22 134 Pfam PF13673 Acetyltransferase (GNAT) domain 38 132 1.3E-14 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS32540 784834bd537e77eb987307aed7a64a22 134 Gene3D G3DSA:3.40.630.30 9 127 2.0E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS08765 eb22f92641712d2a47829690eafb82fc 219 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 192 1.9E-34 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS08765 eb22f92641712d2a47829690eafb82fc 219 SUPERFAMILY SSF53254 4 199 2.36E-39 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS08765 eb22f92641712d2a47829690eafb82fc 219 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 9 18 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 SMD11_RS08765 eb22f92641712d2a47829690eafb82fc 219 SMART SM00855 6 166 5.5E-20 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS08765 eb22f92641712d2a47829690eafb82fc 219 Gene3D G3DSA:3.40.50.1240 4 195 4.2E-43 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS02840 195e0d7877e395fd2270fe68c69dbafc 330 Gene3D G3DSA:3.40.50.10440 12 182 6.7E-71 T 06-07-2017 SMD11_RS02840 195e0d7877e395fd2270fe68c69dbafc 330 SUPERFAMILY SSF82549 11 329 5.23E-117 T 06-07-2017 SMD11_RS02840 195e0d7877e395fd2270fe68c69dbafc 330 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 325 4.1E-146 T 06-07-2017 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 SMD11_RS02840 195e0d7877e395fd2270fe68c69dbafc 330 Gene3D G3DSA:3.30.1180.20 185 329 4.9E-52 T 06-07-2017 SMD11_RS02840 195e0d7877e395fd2270fe68c69dbafc 330 Pfam PF02733 Dak1 domain 17 324 7.4E-126 T 06-07-2017 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SMD11_RS06695 d4e9729848a7e5bdcf87f36167f62dd4 414 Gene3D G3DSA:3.40.50.980 232 373 6.1E-37 T 06-07-2017 SMD11_RS06695 d4e9729848a7e5bdcf87f36167f62dd4 414 Pfam PF00501 AMP-binding enzyme 60 392 1.3E-68 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS06695 d4e9729848a7e5bdcf87f36167f62dd4 414 ProSitePatterns PS00455 Putative AMP-binding domain signature. 206 217 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS06695 d4e9729848a7e5bdcf87f36167f62dd4 414 SUPERFAMILY SSF56801 51 392 1.44E-82 T 06-07-2017 SMD11_RS06695 d4e9729848a7e5bdcf87f36167f62dd4 414 Gene3D G3DSA:3.40.50.980 52 229 7.9E-47 T 06-07-2017 SMD11_RS16215 9d5cc387dd9a2e048c112f7fbf426c62 308 Pfam PF05175 Methyltransferase small domain 119 199 4.1E-9 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 SMD11_RS16215 9d5cc387dd9a2e048c112f7fbf426c62 308 Gene3D G3DSA:1.10.8.10 40 75 1.2E-5 T 06-07-2017 SMD11_RS16215 9d5cc387dd9a2e048c112f7fbf426c62 308 SUPERFAMILY SSF53335 43 268 2.24E-41 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS16215 9d5cc387dd9a2e048c112f7fbf426c62 308 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 18 281 1.9E-118 T 06-07-2017 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase SMD11_RS16215 9d5cc387dd9a2e048c112f7fbf426c62 308 Gene3D G3DSA:3.40.50.150 77 268 7.3E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS16215 9d5cc387dd9a2e048c112f7fbf426c62 308 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 44 257 2.8E-39 T 06-07-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 SMD11_RS01450 5ecfe7947068d4541a5ed5667d1187d0 403 Pfam PF00067 Cytochrome P450 186 372 1.1E-20 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS01450 5ecfe7947068d4541a5ed5667d1187d0 403 Gene3D G3DSA:1.10.630.10 18 403 1.1E-107 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS01450 5ecfe7947068d4541a5ed5667d1187d0 403 SUPERFAMILY SSF48264 17 403 7.2E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS01450 5ecfe7947068d4541a5ed5667d1187d0 403 PRINTS PR00359 B-class P450 signature 138 154 1.1E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01450 5ecfe7947068d4541a5ed5667d1187d0 403 PRINTS PR00359 B-class P450 signature 276 287 1.1E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01450 5ecfe7947068d4541a5ed5667d1187d0 403 PRINTS PR00359 B-class P450 signature 155 170 1.1E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01450 5ecfe7947068d4541a5ed5667d1187d0 403 PRINTS PR00359 B-class P450 signature 322 337 1.1E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01450 5ecfe7947068d4541a5ed5667d1187d0 403 PRINTS PR00359 B-class P450 signature 294 321 1.1E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01450 5ecfe7947068d4541a5ed5667d1187d0 403 PRINTS PR00359 B-class P450 signature 343 352 1.1E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01450 5ecfe7947068d4541a5ed5667d1187d0 403 PRINTS PR00359 B-class P450 signature 352 363 1.1E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01450 5ecfe7947068d4541a5ed5667d1187d0 403 PRINTS PR00359 B-class P450 signature 89 100 1.1E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS26950 b9bda7f978081e99dab6fcb4afe322b7 167 Pfam PF00583 Acetyltransferase (GNAT) family 61 138 6.7E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS26950 b9bda7f978081e99dab6fcb4afe322b7 167 SUPERFAMILY SSF55729 10 146 1.59E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS26950 b9bda7f978081e99dab6fcb4afe322b7 167 Gene3D G3DSA:3.40.630.30 2 146 4.3E-26 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS06765 840ecfd824a50590c3a7dc9be38b4cc0 489 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 7.0E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS06765 840ecfd824a50590c3a7dc9be38b4cc0 489 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 7.0E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS06765 840ecfd824a50590c3a7dc9be38b4cc0 489 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 7.0E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS06765 840ecfd824a50590c3a7dc9be38b4cc0 489 PRINTS PR00111 Alpha/beta hydrolase fold signature 207 221 7.0E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS06765 840ecfd824a50590c3a7dc9be38b4cc0 489 Gene3D G3DSA:3.40.50.1820 14 262 1.3E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS06765 840ecfd824a50590c3a7dc9be38b4cc0 489 SUPERFAMILY SSF69118 364 481 1.15E-29 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS06765 840ecfd824a50590c3a7dc9be38b4cc0 489 Pfam PF02627 Carboxymuconolactone decarboxylase family 394 475 5.4E-23 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS06765 840ecfd824a50590c3a7dc9be38b4cc0 489 Gene3D G3DSA:1.20.1290.10 366 482 6.4E-26 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS06765 840ecfd824a50590c3a7dc9be38b4cc0 489 SUPERFAMILY SSF53474 14 261 2.54E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS06765 840ecfd824a50590c3a7dc9be38b4cc0 489 Pfam PF00561 alpha/beta hydrolase fold 26 147 5.2E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS21495 ce103e06d3c3b5b7fc8ca7bb5a04a152 265 Gene3D G3DSA:1.10.3720.10 13 262 3.8E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21495 ce103e06d3c3b5b7fc8ca7bb5a04a152 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 257 1.1E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21495 ce103e06d3c3b5b7fc8ca7bb5a04a152 265 SUPERFAMILY SSF161098 16 252 8.5E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS24600 a04b38f4c9acc68be8315fde5e7cd443 195 Pfam PF01738 Dienelactone hydrolase family 5 193 2.5E-23 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 SMD11_RS24600 a04b38f4c9acc68be8315fde5e7cd443 195 Gene3D G3DSA:3.40.50.1820 6 192 2.1E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS24600 a04b38f4c9acc68be8315fde5e7cd443 195 SUPERFAMILY SSF53474 6 192 8.98E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS21185 d69098ab3a55df0a145ca3ad1815097d 803 Pfam PF05547 Immune inhibitor A peptidase M6 104 794 2.6E-214 T 06-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMD11_RS21185 d69098ab3a55df0a145ca3ad1815097d 803 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 171 478 5.6E-83 T 06-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMD11_RS21185 d69098ab3a55df0a145ca3ad1815097d 803 PIRSF PIRSF007519 2 803 3.7E-214 T 06-07-2017 IPR012300 Peptidase M6, InhA SMD11_RS21185 d69098ab3a55df0a145ca3ad1815097d 803 Gene3D G3DSA:3.40.390.10 347 426 3.2E-25 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD11_RS21185 d69098ab3a55df0a145ca3ad1815097d 803 Gene3D G3DSA:3.40.390.10 236 284 3.2E-25 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD11_RS21185 d69098ab3a55df0a145ca3ad1815097d 803 SUPERFAMILY SSF55486 347 426 2.48E-16 T 06-07-2017 SMD11_RS21185 d69098ab3a55df0a145ca3ad1815097d 803 SUPERFAMILY SSF55486 234 293 2.48E-16 T 06-07-2017 SMD11_RS06395 b213dff8c2984b45d83cdc6648258d9b 277 Gene3D G3DSA:3.30.1360.130 216 267 1.6E-7 T 06-07-2017 SMD11_RS06395 b213dff8c2984b45d83cdc6648258d9b 277 PIRSF PIRSF015853 1 274 1.2E-94 T 06-07-2017 IPR007035 Peptidase M55, D-aminopeptidase SMD11_RS06395 b213dff8c2984b45d83cdc6648258d9b 277 Gene3D G3DSA:3.40.50.10780 1 213 2.7E-76 T 06-07-2017 IPR027476 D-aminopeptidase, N-terminal SMD11_RS06395 b213dff8c2984b45d83cdc6648258d9b 277 SUPERFAMILY SSF63992 1 267 3.79E-84 T 06-07-2017 IPR007035 Peptidase M55, D-aminopeptidase SMD11_RS06395 b213dff8c2984b45d83cdc6648258d9b 277 Pfam PF04951 D-aminopeptidase 1 262 5.1E-93 T 06-07-2017 IPR007035 Peptidase M55, D-aminopeptidase SMD11_RS23550 2d624a1ff4f491ca29cedf0ccd26f191 267 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 15 241 2.3E-20 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD11_RS23550 2d624a1ff4f491ca29cedf0ccd26f191 267 Pfam PF07398 MDMPI C-terminal domain 155 259 2.5E-14 T 06-07-2017 IPR010872 MDMPI C-terminal SMD11_RS23550 2d624a1ff4f491ca29cedf0ccd26f191 267 SUPERFAMILY SSF109854 16 148 4.35E-9 T 06-07-2017 SMD11_RS23550 2d624a1ff4f491ca29cedf0ccd26f191 267 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 15 142 2.4E-20 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD11_RS04725 5ab34747af0658b77794451cadc3ce2a 678 SUPERFAMILY SSF117892 57 175 7.59E-10 T 06-07-2017 IPR001107 Band 7 domain SMD11_RS04725 5ab34747af0658b77794451cadc3ce2a 678 Pfam PF01145 SPFH domain / Band 7 family 32 219 5.9E-5 T 06-07-2017 IPR001107 Band 7 domain SMD11_RS19615 87845fe9096f8109e1c9e9306ac84db4 365 Pfam PF14027 Protein of unknown function (DUF4243) 31 336 3.9E-19 T 06-07-2017 IPR025337 Domain of unknown function DUF4243 SMD11_RS10430 da4b2d1213de5a569705e3e8fbd3f7d8 493 Pfam PF00375 Sodium:dicarboxylate symporter family 61 451 9.7E-99 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS10430 da4b2d1213de5a569705e3e8fbd3f7d8 493 Gene3D G3DSA:1.10.3860.10 57 456 1.5E-102 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS10430 da4b2d1213de5a569705e3e8fbd3f7d8 493 SUPERFAMILY SSF118215 61 451 2.88E-101 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS10430 da4b2d1213de5a569705e3e8fbd3f7d8 493 PRINTS PR00173 Glutamate-aspartate symporter signature 241 260 3.7E-27 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS10430 da4b2d1213de5a569705e3e8fbd3f7d8 493 PRINTS PR00173 Glutamate-aspartate symporter signature 126 151 3.7E-27 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS10430 da4b2d1213de5a569705e3e8fbd3f7d8 493 PRINTS PR00173 Glutamate-aspartate symporter signature 59 79 3.7E-27 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS10430 da4b2d1213de5a569705e3e8fbd3f7d8 493 PRINTS PR00173 Glutamate-aspartate symporter signature 194 216 3.7E-27 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS10430 da4b2d1213de5a569705e3e8fbd3f7d8 493 PRINTS PR00173 Glutamate-aspartate symporter signature 342 368 3.7E-27 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS10430 da4b2d1213de5a569705e3e8fbd3f7d8 493 PRINTS PR00173 Glutamate-aspartate symporter signature 377 396 3.7E-27 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 SMD11_RS32580 114414f7e0be6a6372494820e2aa758f 402 Pfam PF07690 Major Facilitator Superfamily 28 275 2.3E-21 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS32580 114414f7e0be6a6372494820e2aa758f 402 Gene3D G3DSA:1.20.1250.20 223 398 7.4E-7 T 06-07-2017 SMD11_RS32580 114414f7e0be6a6372494820e2aa758f 402 SUPERFAMILY SSF103473 12 400 1.31E-42 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS32580 114414f7e0be6a6372494820e2aa758f 402 Gene3D G3DSA:1.20.1250.20 23 201 2.4E-24 T 06-07-2017 SMD11_RS29840 06de35f0f84552cf4a14c7b4019516d8 258 SUPERFAMILY SSF56214 32 120 1.66E-18 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS29840 06de35f0f84552cf4a14c7b4019516d8 258 Gene3D G3DSA:3.90.470.20 38 132 3.4E-22 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS29840 06de35f0f84552cf4a14c7b4019516d8 258 SUPERFAMILY SSF56214 127 229 5.06E-21 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS29840 06de35f0f84552cf4a14c7b4019516d8 258 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 128 190 1.9E-11 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS29840 06de35f0f84552cf4a14c7b4019516d8 258 Gene3D G3DSA:3.90.470.20 133 190 1.6E-13 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS01810 1485fb12be842843dd8157138c5bd263 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 1.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS01810 1485fb12be842843dd8157138c5bd263 191 Gene3D G3DSA:1.10.357.10 6 189 5.2E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS01810 1485fb12be842843dd8157138c5bd263 191 SUPERFAMILY SSF46689 2 65 2.89E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 SUPERFAMILY SSF57884 7 88 4.45E-32 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 Gene3D G3DSA:1.10.340.30 332 446 2.3E-34 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 Gene3D G3DSA:1.10.10.60 88 142 8.5E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 SMART SM00478 339 490 4.5E-17 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 142 184 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 Pfam PF12833 Helix-turn-helix domain 111 189 2.0E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 Pfam PF06029 AlkA N-terminal domain 206 329 2.4E-31 T 06-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 SUPERFAMILY SSF55945 206 310 1.73E-19 T 06-07-2017 SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 335 466 1.6E-7 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 Gene3D G3DSA:3.30.310.20 206 329 2.9E-32 T 06-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 Pfam PF02805 Metal binding domain of Ada 13 76 9.9E-30 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 Gene3D G3DSA:1.10.10.60 143 190 7.2E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 SMART SM00342 105 188 4.2E-18 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 Gene3D G3DSA:3.40.10.10 6 87 9.0E-35 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 SUPERFAMILY SSF46689 142 190 4.93E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 SMART SM01009 205 329 2.0E-42 T 06-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 SUPERFAMILY SSF48150 319 486 1.61E-41 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD11_RS07165 b864a47eeba281b4010c9e952d5146e0 493 Gene3D G3DSA:1.10.1670.10 447 489 2.6E-11 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SMD11_RS31335 7b4bbf5d6b7958abbdb7f9944841a6ad 528 Gene3D G3DSA:3.20.20.360 70 406 1.6E-115 T 06-07-2017 SMD11_RS31335 7b4bbf5d6b7958abbdb7f9944841a6ad 528 Gene3D G3DSA:1.20.1220.12 413 510 1.3E-23 T 06-07-2017 SMD11_RS31335 7b4bbf5d6b7958abbdb7f9944841a6ad 528 PIRSF PIRSF001363 1 521 1.2E-223 T 06-07-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMD11_RS31335 7b4bbf5d6b7958abbdb7f9944841a6ad 528 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 21 517 2.2E-217 T 06-07-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMD11_RS31335 7b4bbf5d6b7958abbdb7f9944841a6ad 528 ProSitePatterns PS00510 Malate synthase signature. 264 279 - T 06-07-2017 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMD11_RS31335 7b4bbf5d6b7958abbdb7f9944841a6ad 528 SUPERFAMILY SSF51645 5 519 1.83E-171 T 06-07-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMD11_RS31335 7b4bbf5d6b7958abbdb7f9944841a6ad 528 Pfam PF01274 Malate synthase 12 517 7.7E-179 T 06-07-2017 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMD11_RS12760 fb673fb7a468717ecea78fd80af5fd28 202 Pfam PF05685 Putative restriction endonuclease 24 191 3.6E-21 T 06-07-2017 IPR008538 Domain of unknown function DUF820 SMD11_RS12760 fb673fb7a468717ecea78fd80af5fd28 202 Gene3D G3DSA:3.90.1570.10 28 165 1.6E-17 T 06-07-2017 IPR012296 Nuclease, putative, TT1808 SMD11_RS12760 fb673fb7a468717ecea78fd80af5fd28 202 SUPERFAMILY SSF52980 28 166 3.22E-16 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD11_RS03400 e7bd15ff4519f2f7149a24e62908009b 235 SUPERFAMILY SSF48317 27 222 1.22E-28 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS03400 e7bd15ff4519f2f7149a24e62908009b 235 SMART SM00014 103 219 1.1E-11 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS03400 e7bd15ff4519f2f7149a24e62908009b 235 Pfam PF01569 PAP2 superfamily 108 219 2.4E-20 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS03400 e7bd15ff4519f2f7149a24e62908009b 235 Gene3D G3DSA:1.20.144.10 41 220 1.3E-25 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS02250 12e463c9c9c23f3e514c9e08965cd9fa 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 31 261 4.1E-56 T 06-07-2017 SMD11_RS02250 12e463c9c9c23f3e514c9e08965cd9fa 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 1.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02250 12e463c9c9c23f3e514c9e08965cd9fa 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 1.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02250 12e463c9c9c23f3e514c9e08965cd9fa 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 1.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02250 12e463c9c9c23f3e514c9e08965cd9fa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 1.1E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02250 12e463c9c9c23f3e514c9e08965cd9fa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 1.1E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02250 12e463c9c9c23f3e514c9e08965cd9fa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 24 41 1.1E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02250 12e463c9c9c23f3e514c9e08965cd9fa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 1.1E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02250 12e463c9c9c23f3e514c9e08965cd9fa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 1.1E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02250 12e463c9c9c23f3e514c9e08965cd9fa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 1.1E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS02250 12e463c9c9c23f3e514c9e08965cd9fa 262 SUPERFAMILY SSF51735 21 262 3.31E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS02250 12e463c9c9c23f3e514c9e08965cd9fa 262 Gene3D G3DSA:3.40.50.720 18 262 3.0E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS34360 7f417e6ad221304e06233d9b080d4a0b 270 SUPERFAMILY SSF53335 13 130 2.87E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS34360 7f417e6ad221304e06233d9b080d4a0b 270 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 9 133 4.4E-27 T 06-07-2017 SMD11_RS34360 7f417e6ad221304e06233d9b080d4a0b 270 Gene3D G3DSA:3.40.50.150 8 162 3.4E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29820 269959d83ae27dac4465be8f2db340cc 314 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 159 309 1.0E-7 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase SMD11_RS29820 269959d83ae27dac4465be8f2db340cc 314 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 8 149 4.5E-14 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase SMD11_RS29820 269959d83ae27dac4465be8f2db340cc 314 SUPERFAMILY SSF55961 159 312 1.36E-25 T 06-07-2017 SMD11_RS29820 269959d83ae27dac4465be8f2db340cc 314 Gene3D G3DSA:3.30.530.20 161 308 3.3E-5 T 06-07-2017 IPR023393 START-like domain SMD11_RS29820 269959d83ae27dac4465be8f2db340cc 314 Gene3D G3DSA:3.30.530.20 8 126 4.3E-12 T 06-07-2017 IPR023393 START-like domain SMD11_RS29820 269959d83ae27dac4465be8f2db340cc 314 SUPERFAMILY SSF55961 9 153 5.85E-38 T 06-07-2017 SMD11_RS04490 6ff4385755eac86bb1dbf8070b203590 907 Pfam PF00196 Bacterial regulatory proteins, luxR family 853 903 3.9E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS04490 6ff4385755eac86bb1dbf8070b203590 907 SUPERFAMILY SSF48452 555 648 1.03E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS04490 6ff4385755eac86bb1dbf8070b203590 907 Gene3D G3DSA:1.25.40.10 558 728 1.7E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS04490 6ff4385755eac86bb1dbf8070b203590 907 Gene3D G3DSA:1.10.10.10 845 903 1.5E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04490 6ff4385755eac86bb1dbf8070b203590 907 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 867 883 1.6E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS04490 6ff4385755eac86bb1dbf8070b203590 907 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 883 895 1.6E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS04490 6ff4385755eac86bb1dbf8070b203590 907 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 853 867 1.6E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS04490 6ff4385755eac86bb1dbf8070b203590 907 ProSitePatterns PS00622 LuxR-type HTH domain signature. 867 894 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS04490 6ff4385755eac86bb1dbf8070b203590 907 Pfam PF13191 AAA ATPase domain 3 142 5.1E-13 T 06-07-2017 SMD11_RS04490 6ff4385755eac86bb1dbf8070b203590 907 SUPERFAMILY SSF52540 3 218 2.04E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04490 6ff4385755eac86bb1dbf8070b203590 907 Gene3D G3DSA:3.40.50.300 5 146 3.5E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04490 6ff4385755eac86bb1dbf8070b203590 907 SUPERFAMILY SSF46894 842 903 6.8E-14 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS04490 6ff4385755eac86bb1dbf8070b203590 907 SMART SM00421 850 907 1.9E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS22620 99c683c8acba5e59e7707c27192c6866 338 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 334 2.8E-103 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SMD11_RS22620 99c683c8acba5e59e7707c27192c6866 338 SUPERFAMILY SSF55781 71 336 7.85E-59 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS22620 99c683c8acba5e59e7707c27192c6866 338 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 328 28.696 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SMD11_RS22620 99c683c8acba5e59e7707c27192c6866 338 Gene3D G3DSA:1.10.10.10 2 84 1.2E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS22620 99c683c8acba5e59e7707c27192c6866 338 Gene3D G3DSA:3.30.450.40 176 337 2.0E-44 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS22620 99c683c8acba5e59e7707c27192c6866 338 PIRSF PIRSF005485 1 338 1.5E-101 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SMD11_RS22620 99c683c8acba5e59e7707c27192c6866 338 SUPERFAMILY SSF46785 2 82 9.69E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS22620 99c683c8acba5e59e7707c27192c6866 338 Pfam PF01628 HrcA protein C terminal domain 103 321 2.8E-63 T 06-07-2017 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 SMD11_RS11500 bb6eac9363362d7adaa14a2d5ae9ec80 362 SUPERFAMILY SSF54211 236 345 1.29E-19 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS11500 bb6eac9363362d7adaa14a2d5ae9ec80 362 SMART SM00228 131 197 4.4E-5 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS11500 bb6eac9363362d7adaa14a2d5ae9ec80 362 Pfam PF13180 PDZ domain 139 192 1.5E-10 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS11500 bb6eac9363362d7adaa14a2d5ae9ec80 362 Gene3D G3DSA:3.30.230.10 249 345 1.2E-21 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS11500 bb6eac9363362d7adaa14a2d5ae9ec80 362 SUPERFAMILY SSF50156 138 254 1.71E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS11500 bb6eac9363362d7adaa14a2d5ae9ec80 362 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 252 344 5.6E-9 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 SMD11_RS11500 bb6eac9363362d7adaa14a2d5ae9ec80 362 Gene3D G3DSA:2.30.42.10 140 226 4.2E-15 T 06-07-2017 IPR001478 PDZ domain GO:0005515 SMD11_RS31300 6bf3fc5d400b73a2062e35eac0a64dec 253 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 1 244 2.2E-13 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS31300 6bf3fc5d400b73a2062e35eac0a64dec 253 SUPERFAMILY SSF56219 1 249 2.09E-34 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS31300 6bf3fc5d400b73a2062e35eac0a64dec 253 Gene3D G3DSA:3.60.10.10 16 252 1.8E-11 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS09660 e8b6ccd535c77d70a1cfa0eabc8ea3be 490 PIRSF PIRSF002744 2 475 1.2E-99 T 06-07-2017 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 SMD11_RS09660 e8b6ccd535c77d70a1cfa0eabc8ea3be 490 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 20 441 7.9E-86 T 06-07-2017 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 SMD11_RS33025 cb68e68737f605d7d04c629a1ec0cb3e 321 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 9 308 4.0E-99 T 06-07-2017 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 SMD11_RS33025 cb68e68737f605d7d04c629a1ec0cb3e 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 5.2E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS33025 cb68e68737f605d7d04c629a1ec0cb3e 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 5.2E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS33025 cb68e68737f605d7d04c629a1ec0cb3e 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 138 5.2E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS33025 cb68e68737f605d7d04c629a1ec0cb3e 321 Gene3D G3DSA:3.40.50.1820 9 316 3.0E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS33025 cb68e68737f605d7d04c629a1ec0cb3e 321 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 111 125 5.0E-12 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD11_RS33025 cb68e68737f605d7d04c629a1ec0cb3e 321 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 74 5.0E-12 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD11_RS33025 cb68e68737f605d7d04c629a1ec0cb3e 321 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 37 45 5.0E-12 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 SMD11_RS33025 cb68e68737f605d7d04c629a1ec0cb3e 321 Pfam PF00561 alpha/beta hydrolase fold 38 300 1.7E-29 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS33025 cb68e68737f605d7d04c629a1ec0cb3e 321 SUPERFAMILY SSF53474 4 316 5.1E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS33025 cb68e68737f605d7d04c629a1ec0cb3e 321 PIRSF PIRSF006431 1 320 2.7E-122 T 06-07-2017 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 SMD11_RS00795 b6abef437fff42a3b170dad358bc852d 517 Pfam PF13193 AMP-binding enzyme C-terminal domain 346 421 8.0E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS00795 b6abef437fff42a3b170dad358bc852d 517 Gene3D G3DSA:3.40.50.980 92 239 6.2E-33 T 06-07-2017 SMD11_RS00795 b6abef437fff42a3b170dad358bc852d 517 Gene3D G3DSA:1.10.1200.10 450 513 3.7E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS00795 b6abef437fff42a3b170dad358bc852d 517 Pfam PF00550 Phosphopantetheine attachment site 447 510 2.2E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS00795 b6abef437fff42a3b170dad358bc852d 517 ProSitePatterns PS00012 Phosphopantetheine attachment site. 469 484 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS00795 b6abef437fff42a3b170dad358bc852d 517 Gene3D G3DSA:3.40.50.980 2 91 5.3E-25 T 06-07-2017 SMD11_RS00795 b6abef437fff42a3b170dad358bc852d 517 Gene3D G3DSA:2.30.38.10 253 327 3.8E-21 T 06-07-2017 SMD11_RS00795 b6abef437fff42a3b170dad358bc852d 517 Pfam PF00501 AMP-binding enzyme 6 338 1.9E-70 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS00795 b6abef437fff42a3b170dad358bc852d 517 Gene3D G3DSA:3.30.300.30 335 449 2.2E-29 T 06-07-2017 SMD11_RS00795 b6abef437fff42a3b170dad358bc852d 517 SUPERFAMILY SSF56801 3 458 4.19E-117 T 06-07-2017 SMD11_RS00795 b6abef437fff42a3b170dad358bc852d 517 SUPERFAMILY SSF47336 439 511 5.37E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS00795 b6abef437fff42a3b170dad358bc852d 517 ProSitePatterns PS00455 Putative AMP-binding domain signature. 85 96 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS20045 03ad2dde65422260af0367c790d12ca5 539 SUPERFAMILY SSF56601 239 537 4.97E-53 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS20045 03ad2dde65422260af0367c790d12ca5 539 Pfam PF00905 Penicillin binding protein transpeptidase domain 265 536 2.6E-38 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD11_RS20045 03ad2dde65422260af0367c790d12ca5 539 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 55 161 1.4E-6 T 06-07-2017 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 SMD11_RS20045 03ad2dde65422260af0367c790d12ca5 539 Gene3D G3DSA:3.40.710.10 245 537 1.2E-55 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS06760 ed881da514d69356be28828fb16ce03b 213 SUPERFAMILY SSF56281 1 60 4.74E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS06760 ed881da514d69356be28828fb16ce03b 213 SUPERFAMILY SSF56281 87 180 4.74E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS06760 ed881da514d69356be28828fb16ce03b 213 Pfam PF13483 Beta-lactamase superfamily domain 2 175 1.3E-21 T 06-07-2017 SMD11_RS06760 ed881da514d69356be28828fb16ce03b 213 SMART SM00849 7 175 0.0039 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS06760 ed881da514d69356be28828fb16ce03b 213 Gene3D G3DSA:3.60.15.10 1 213 4.6E-26 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS03820 7d6053430ceca4623b95ae2cc030a216 336 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD11_RS03820 7d6053430ceca4623b95ae2cc030a216 336 SUPERFAMILY SSF51735 137 303 1.32E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03820 7d6053430ceca4623b95ae2cc030a216 336 SUPERFAMILY SSF50129 1 161 6.09E-51 T 06-07-2017 IPR011032 GroES-like SMD11_RS03820 7d6053430ceca4623b95ae2cc030a216 336 Pfam PF00107 Zinc-binding dehydrogenase 174 299 6.7E-21 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS03820 7d6053430ceca4623b95ae2cc030a216 336 SMART SM00829 10 333 2.8E-8 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS03820 7d6053430ceca4623b95ae2cc030a216 336 Gene3D G3DSA:3.90.180.10 1 165 1.1E-60 T 06-07-2017 IPR011032 GroES-like SMD11_RS03820 7d6053430ceca4623b95ae2cc030a216 336 Gene3D G3DSA:3.40.50.720 166 283 6.7E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03820 7d6053430ceca4623b95ae2cc030a216 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 2.7E-27 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS29490 4d1df6f9079dfb358f97a2b6b2788861 469 Pfam PF05694 56kDa selenium binding protein (SBP56) 6 466 2.7E-185 T 06-07-2017 IPR008826 Selenium-binding protein GO:0008430 SMD11_RS29490 4d1df6f9079dfb358f97a2b6b2788861 469 SUPERFAMILY SSF75011 88 402 1.96E-18 T 06-07-2017 SMD11_RS29490 4d1df6f9079dfb358f97a2b6b2788861 469 Gene3D G3DSA:2.130.10.10 322 403 5.5E-11 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS29490 4d1df6f9079dfb358f97a2b6b2788861 469 Gene3D G3DSA:2.130.10.10 92 246 5.5E-11 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS14745 b8d8446a617f8247dd6aae2451600d89 173 Gene3D G3DSA:2.30.110.10 9 164 1.1E-15 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS14745 b8d8446a617f8247dd6aae2451600d89 173 SUPERFAMILY SSF50475 9 168 7.0E-18 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS12430 d9e232b6fd0617d62c31236789012734 705 SUPERFAMILY SSF52833 1 127 3.55E-29 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS12430 d9e232b6fd0617d62c31236789012734 705 Gene3D G3DSA:3.40.30.10 20 144 1.9E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS12430 d9e232b6fd0617d62c31236789012734 705 PIRSF PIRSF006402 1 705 7.1E-202 T 06-07-2017 IPR024705 Spermatogenesis-associated protein 20 SMD11_RS12430 d9e232b6fd0617d62c31236789012734 705 Gene3D G3DSA:1.50.10.10 439 593 3.1E-4 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 SMD11_RS12430 d9e232b6fd0617d62c31236789012734 705 Gene3D G3DSA:1.50.10.10 207 336 2.8E-16 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 SMD11_RS12430 d9e232b6fd0617d62c31236789012734 705 Pfam PF03190 Protein of unknown function, DUF255 3 163 8.5E-74 T 06-07-2017 IPR004879 Domain of unknown function DUF255 SMD11_RS12430 d9e232b6fd0617d62c31236789012734 705 SUPERFAMILY SSF48208 370 563 7.94E-76 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD11_RS12430 d9e232b6fd0617d62c31236789012734 705 SUPERFAMILY SSF48208 204 335 7.94E-76 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD11_RS04165 863404cb80de26a727c19748b69bd8cf 310 SMART SM00644 164 293 1.6E-33 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS04165 863404cb80de26a727c19748b69bd8cf 310 Gene3D G3DSA:3.40.80.10 155 308 5.8E-39 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS04165 863404cb80de26a727c19748b69bd8cf 310 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 173 294 7.6E-20 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS04165 863404cb80de26a727c19748b69bd8cf 310 SUPERFAMILY SSF55846 163 307 2.09E-37 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS33155 180b85b60144ca5d1c5f26c2d576e9a2 140 SUPERFAMILY SSF160719 22 128 1.14E-33 T 06-07-2017 SMD11_RS33155 180b85b60144ca5d1c5f26c2d576e9a2 140 Gene3D G3DSA:3.10.450.40 3 127 4.2E-46 T 06-07-2017 SMD11_RS33155 180b85b60144ca5d1c5f26c2d576e9a2 140 Pfam PF04965 Gene 25-like lysozyme 28 116 4.3E-24 T 06-07-2017 IPR007048 GpW/Gp25/anti-adapter protein IraD SMD11_RS08755 6c76312ed06a6d6c9bc77d82fb614637 233 Pfam PF01351 Ribonuclease HII 24 200 2.4E-33 T 06-07-2017 IPR024567 Ribonuclease HII/HIII domain SMD11_RS08755 6c76312ed06a6d6c9bc77d82fb614637 233 SUPERFAMILY SSF53098 18 207 6.53E-57 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS08755 6c76312ed06a6d6c9bc77d82fb614637 233 Gene3D G3DSA:3.30.420.10 22 162 3.8E-40 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS08755 6c76312ed06a6d6c9bc77d82fb614637 233 Hamap MF_00052_B Ribonuclease HII [rnhB]. 22 202 35.077 T 06-07-2017 IPR022898 Ribonuclease HII GO:0004523 SMD11_RS30385 9a46c3f95394a5196e20a8557725ec86 175 Gene3D G3DSA:2.80.10.50 117 173 9.4E-4 T 06-07-2017 SMD11_RS30385 9a46c3f95394a5196e20a8557725ec86 175 Gene3D G3DSA:2.80.10.50 32 116 8.5E-10 T 06-07-2017 SMD11_RS30385 9a46c3f95394a5196e20a8557725ec86 175 SUPERFAMILY SSF50370 24 173 2.44E-20 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS30385 9a46c3f95394a5196e20a8557725ec86 175 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 63 152 1.7E-14 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS30615 739c5c0dcd17bb1beb068956aac62efd 128 Gene3D G3DSA:3.10.180.10 3 124 1.7E-9 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS30615 739c5c0dcd17bb1beb068956aac62efd 128 SUPERFAMILY SSF54593 1 125 3.1E-11 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS14185 8e8c6787a514ae3e44b1fb052bfbe716 246 SUPERFAMILY SSF63817 73 203 2.55E-11 T 06-07-2017 IPR023365 Sortase domain SMD11_RS14185 8e8c6787a514ae3e44b1fb052bfbe716 246 Gene3D G3DSA:2.40.260.10 105 204 4.4E-8 T 06-07-2017 IPR023365 Sortase domain SMD11_RS14185 8e8c6787a514ae3e44b1fb052bfbe716 246 Pfam PF04203 Sortase family 75 215 2.5E-14 T 06-07-2017 IPR005754 Sortase family SMD11_RS07080 02af0e85d1e2baa70b7546647b78c723 569 Pfam PF13556 PucR C-terminal helix-turn-helix domain 510 567 1.2E-21 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain SMD11_RS07080 02af0e85d1e2baa70b7546647b78c723 569 Pfam PF07905 Purine catabolism regulatory protein-like family 6 120 3.6E-28 T 06-07-2017 IPR012914 Purine catabolism PurC-like domain SMD11_RS16120 212fce999c867f6c1bc15015ba6087f0 294 Gene3D G3DSA:3.20.20.30 138 270 2.4E-14 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS16120 212fce999c867f6c1bc15015ba6087f0 294 Gene3D G3DSA:3.20.20.30 10 126 3.5E-8 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS16120 212fce999c867f6c1bc15015ba6087f0 294 Pfam PF00296 Luciferase-like monooxygenase 24 261 1.7E-12 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS16120 212fce999c867f6c1bc15015ba6087f0 294 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 7 290 2.7E-105 T 06-07-2017 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted SMD11_RS16120 212fce999c867f6c1bc15015ba6087f0 294 SUPERFAMILY SSF51679 10 266 2.21E-33 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS11310 05dd47916ca9506a3afe6a1b772fc786 325 SMART SM00471 25 101 0.0015 T 06-07-2017 IPR003607 HD/PDEase domain SMD11_RS11310 05dd47916ca9506a3afe6a1b772fc786 325 SUPERFAMILY SSF109604 28 126 2.62E-13 T 06-07-2017 SMD11_RS11310 05dd47916ca9506a3afe6a1b772fc786 325 Pfam PF01966 HD domain 30 77 2.8E-6 T 06-07-2017 IPR006674 HD domain SMD11_RS11310 05dd47916ca9506a3afe6a1b772fc786 325 Gene3D G3DSA:1.10.3210.10 30 124 5.3E-8 T 06-07-2017 IPR006674 HD domain SMD11_RS24880 3c0df31d0c1f7f0d5505eeb08d4801c2 505 SUPERFAMILY SSF51905 41 295 3.14E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24880 3c0df31d0c1f7f0d5505eeb08d4801c2 505 Gene3D G3DSA:3.50.50.60 151 275 2.0E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24880 3c0df31d0c1f7f0d5505eeb08d4801c2 505 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 43 388 4.2E-113 T 06-07-2017 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase SMD11_RS33530 0bd5f7ad831038eaa8efbb074aae342f 372 Gene3D G3DSA:2.40.180.10 34 357 1.2E-25 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS33530 0bd5f7ad831038eaa8efbb074aae342f 372 SUPERFAMILY SSF56634 36 356 1.14E-39 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS10730 c61fcb3a4e7edc1f8d3977c2c3c6cd48 220 Pfam PF01939 Protein of unknown function DUF91 2 220 4.6E-85 T 06-07-2017 IPR002793 Endonuclease NucS SMD11_RS10730 c61fcb3a4e7edc1f8d3977c2c3c6cd48 220 Gene3D G3DSA:3.40.1350.10 116 154 7.7E-4 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 SMD11_RS10730 c61fcb3a4e7edc1f8d3977c2c3c6cd48 220 Hamap MF_00722 Endonuclease NucS [nucS]. 1 212 32.11 T 06-07-2017 IPR002793 Endonuclease NucS SMD11_RS16820 f60d0044ac8bc91a9bb5e6ecd66d8c6c 485 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 23 482 6.9E-246 T 06-07-2017 IPR014065 tRNA adenylyltransferase SMD11_RS16820 f60d0044ac8bc91a9bb5e6ecd66d8c6c 485 Gene3D G3DSA:1.10.3090.10 427 449 2.4E-60 T 06-07-2017 SMD11_RS16820 f60d0044ac8bc91a9bb5e6ecd66d8c6c 485 Gene3D G3DSA:1.10.3090.10 173 359 2.4E-60 T 06-07-2017 SMD11_RS16820 f60d0044ac8bc91a9bb5e6ecd66d8c6c 485 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 200 261 1.3E-21 T 06-07-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 SMD11_RS16820 f60d0044ac8bc91a9bb5e6ecd66d8c6c 485 Pfam PF01966 HD domain 275 369 1.7E-15 T 06-07-2017 IPR006674 HD domain SMD11_RS16820 f60d0044ac8bc91a9bb5e6ecd66d8c6c 485 SUPERFAMILY SSF81301 31 170 1.74E-37 T 06-07-2017 SMD11_RS16820 f60d0044ac8bc91a9bb5e6ecd66d8c6c 485 Gene3D G3DSA:3.30.460.10 31 172 1.0E-44 T 06-07-2017 SMD11_RS16820 f60d0044ac8bc91a9bb5e6ecd66d8c6c 485 Pfam PF01743 Poly A polymerase head domain 51 173 3.5E-32 T 06-07-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 SMD11_RS16820 f60d0044ac8bc91a9bb5e6ecd66d8c6c 485 TIGRFAM TIGR00277 HDIG: HDIG domain 272 351 1.1E-17 T 06-07-2017 IPR006675 HDIG domain SMD11_RS16820 f60d0044ac8bc91a9bb5e6ecd66d8c6c 485 SUPERFAMILY SSF81891 171 482 4.71E-71 T 06-07-2017 SMD11_RS16820 f60d0044ac8bc91a9bb5e6ecd66d8c6c 485 SMART SM00471 271 426 7.2E-5 T 06-07-2017 IPR003607 HD/PDEase domain SMD11_RS09015 1431094674c9096ec8e3a485660294e5 919 Gene3D G3DSA:3.40.50.300 516 809 1.2E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09015 1431094674c9096ec8e3a485660294e5 919 SUPERFAMILY SSF52540 515 814 5.29E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09015 1431094674c9096ec8e3a485660294e5 919 SMART SM00843 842 906 9.7E-30 T 06-07-2017 IPR018541 FtsK gamma domain SMD11_RS09015 1431094674c9096ec8e3a485660294e5 919 Pfam PF09397 Ftsk gamma domain 846 903 6.5E-22 T 06-07-2017 IPR018541 FtsK gamma domain SMD11_RS09015 1431094674c9096ec8e3a485660294e5 919 SUPERFAMILY SSF46785 843 908 3.4E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS09015 1431094674c9096ec8e3a485660294e5 919 SMART SM00382 577 775 8.0E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS09015 1431094674c9096ec8e3a485660294e5 919 Pfam PF01580 FtsK/SpoIIIE family 545 742 3.3E-54 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 Pfam PF04542 Sigma-70 region 2 284 353 3.1E-22 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 Gene3D G3DSA:1.10.601.10 121 353 3.6E-69 T 06-07-2017 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 308 321 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 477 503 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 Gene3D G3DSA:1.10.10.10 446 517 2.0E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 Gene3D G3DSA:1.10.10.10 357 408 3.9E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 280 516 9.2E-113 T 06-07-2017 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 PRINTS PR00046 Major sigma-70 factor signature 456 468 7.1E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 PRINTS PR00046 Major sigma-70 factor signature 308 321 7.1E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 PRINTS PR00046 Major sigma-70 factor signature 477 492 7.1E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 PRINTS PR00046 Major sigma-70 factor signature 332 340 7.1E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 PRINTS PR00046 Major sigma-70 factor signature 492 503 7.1E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 SUPERFAMILY SSF88946 216 354 7.85E-54 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 126 517 31.708 T 06-07-2017 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 Pfam PF04539 Sigma-70 region 3 363 439 1.1E-28 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 Pfam PF04545 Sigma-70, region 4 452 505 2.9E-18 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 SUPERFAMILY SSF88659 415 516 2.62E-27 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 SUPERFAMILY SSF88659 357 430 3.92E-21 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 280 505 2.0E-36 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS08710 f1aaa56b785d0c067241e5a33f151af4 517 Pfam PF00140 Sigma-70 factor, region 1.2 219 252 8.1E-17 T 06-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23505 2a912126a3a56f83ded01d1dddc4cebe 972 SUPERFAMILY SSF158745 629 942 1.7E-21 T 06-07-2017 SMD11_RS23505 2a912126a3a56f83ded01d1dddc4cebe 972 Gene3D G3DSA:1.10.510.10 373 443 2.1E-7 T 06-07-2017 SMD11_RS23505 2a912126a3a56f83ded01d1dddc4cebe 972 Gene3D G3DSA:3.30.200.20 240 372 9.3E-11 T 06-07-2017 SMD11_RS23505 2a912126a3a56f83ded01d1dddc4cebe 972 SMART SM00220 240 624 0.0022 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS23505 2a912126a3a56f83ded01d1dddc4cebe 972 Pfam PF05147 Lanthionine synthetase C-like protein 709 806 1.1E-5 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS23505 2a912126a3a56f83ded01d1dddc4cebe 972 SUPERFAMILY SSF56112 240 429 3.51E-22 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS23505 2a912126a3a56f83ded01d1dddc4cebe 972 Pfam PF00069 Protein kinase domain 251 449 3.2E-12 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS23505 2a912126a3a56f83ded01d1dddc4cebe 972 SMART SM01260 626 955 5.7E-6 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 SUPERFAMILY SSF48452 196 341 1.52E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 SUPERFAMILY SSF48452 536 616 1.52E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 Gene3D G3DSA:1.25.40.10 971 1115 4.0E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 Gene3D G3DSA:1.25.40.10 732 948 8.5E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 Gene3D G3DSA:1.25.40.10 175 435 1.3E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 SUPERFAMILY SSF48452 713 749 6.64E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 SUPERFAMILY SSF48452 782 833 6.64E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 Pfam PF12770 CHAT domain 1295 1627 1.1E-40 T 06-07-2017 IPR024983 CHAT domain SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 Pfam PF13374 Tetratricopeptide repeat 807 834 9.4E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 SMART SM00028 1039 1072 120.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 SMART SM00028 804 837 21.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 SMART SM00028 224 257 110.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 SMART SM00028 713 746 430.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 SMART SM00028 304 337 140.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 SMART SM00028 994 1027 410.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 SUPERFAMILY SSF48452 596 704 4.55E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 SUPERFAMILY SSF48452 761 834 4.55E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS01625 fd07b17ed1d1a91338e6233831a95a61 1628 Gene3D G3DSA:1.25.40.10 508 724 1.6E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS04300 09ae6d300339472ea26192f1376c5a4d 1218 Pfam PF02514 CobN/Magnesium Chelatase 103 1198 0.0 T 06-07-2017 IPR003672 CobN/magnesium chelatase GO:0009058 SMD11_RS04300 09ae6d300339472ea26192f1376c5a4d 1218 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 41 1211 0.0 T 06-07-2017 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 SMD11_RS22370 f42677b8ef0023c2bce98d67347cab90 234 SMART SM00448 2 112 9.7E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS22370 f42677b8ef0023c2bce98d67347cab90 234 Pfam PF00072 Response regulator receiver domain 4 113 1.2E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS22370 f42677b8ef0023c2bce98d67347cab90 234 SMART SM00862 146 224 4.1E-18 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS22370 f42677b8ef0023c2bce98d67347cab90 234 Gene3D G3DSA:1.10.10.10 132 225 1.1E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS22370 f42677b8ef0023c2bce98d67347cab90 234 Gene3D G3DSA:3.40.50.2300 1 120 3.9E-39 T 06-07-2017 SMD11_RS22370 f42677b8ef0023c2bce98d67347cab90 234 SUPERFAMILY SSF52172 2 174 5.12E-41 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS22370 f42677b8ef0023c2bce98d67347cab90 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 223 1.5E-18 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS09560 db23a1aac51f46fb7924be93e9272f32 163 SUPERFAMILY SSF55811 6 129 3.25E-23 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS09560 db23a1aac51f46fb7924be93e9272f32 163 Gene3D G3DSA:3.90.79.10 5 150 2.4E-30 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS09560 db23a1aac51f46fb7924be93e9272f32 163 Pfam PF00293 NUDIX domain 7 130 1.1E-24 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS09560 db23a1aac51f46fb7924be93e9272f32 163 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD11_RS09560 db23a1aac51f46fb7924be93e9272f32 163 PRINTS PR00502 NUDIX hydrolase family signature 37 51 1.9E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS09560 db23a1aac51f46fb7924be93e9272f32 163 PRINTS PR00502 NUDIX hydrolase family signature 51 66 1.9E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS07890 5aa67f6f20681d9a139816cec6bdb313 109 Pfam PF00581 Rhodanese-like domain 7 99 1.7E-10 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS07890 5aa67f6f20681d9a139816cec6bdb313 109 Gene3D G3DSA:3.40.250.10 4 108 2.3E-21 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS07890 5aa67f6f20681d9a139816cec6bdb313 109 SUPERFAMILY SSF52821 3 108 2.1E-24 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS07890 5aa67f6f20681d9a139816cec6bdb313 109 ProSitePatterns PS00380 Rhodanese signature 1. 30 41 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 SMD11_RS07890 5aa67f6f20681d9a139816cec6bdb313 109 SMART SM00450 5 104 1.0E-12 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS00410 5adfc40e3bf310681914243455e0eab0 372 Pfam PF12840 Helix-turn-helix domain 291 348 3.7E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00410 5adfc40e3bf310681914243455e0eab0 372 SMART SM00418 290 368 1.3E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS00410 5adfc40e3bf310681914243455e0eab0 372 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 292 307 3.8E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS00410 5adfc40e3bf310681914243455e0eab0 372 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 324 339 3.8E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS00410 5adfc40e3bf310681914243455e0eab0 372 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 339 354 3.8E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS00410 5adfc40e3bf310681914243455e0eab0 372 Gene3D G3DSA:1.10.10.10 284 367 2.3E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00410 5adfc40e3bf310681914243455e0eab0 372 SMART SM00419 305 353 0.003 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SMD11_RS00410 5adfc40e3bf310681914243455e0eab0 372 SUPERFAMILY SSF46785 286 364 2.53E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS29360 3c44710934c35196c27edf520d1ced1d 253 SUPERFAMILY SSF51735 13 251 1.24E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29360 3c44710934c35196c27edf520d1ced1d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.5E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29360 3c44710934c35196c27edf520d1ced1d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.5E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29360 3c44710934c35196c27edf520d1ced1d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.5E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29360 3c44710934c35196c27edf520d1ced1d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.5E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29360 3c44710934c35196c27edf520d1ced1d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.5E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29360 3c44710934c35196c27edf520d1ced1d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.5E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29360 3c44710934c35196c27edf520d1ced1d 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.2E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29360 3c44710934c35196c27edf520d1ced1d 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.2E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29360 3c44710934c35196c27edf520d1ced1d 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.2E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29360 3c44710934c35196c27edf520d1ced1d 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 192 9.0E-6 T 06-07-2017 SMD11_RS29360 3c44710934c35196c27edf520d1ced1d 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 251 5.8E-60 T 06-07-2017 SMD11_RS29360 3c44710934c35196c27edf520d1ced1d 253 Gene3D G3DSA:3.40.50.720 13 251 1.1E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29360 3c44710934c35196c27edf520d1ced1d 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS23075 3f0d56d8ec754319a524476abdaee97e 141 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 138 3.9E-52 T 06-07-2017 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 SMD11_RS23075 3f0d56d8ec754319a524476abdaee97e 141 SUPERFAMILY SSF82784 3 132 1.01E-31 T 06-07-2017 IPR003718 OsmC/Ohr family SMD11_RS23075 3f0d56d8ec754319a524476abdaee97e 141 Gene3D G3DSA:3.30.300.20 4 140 1.5E-43 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta SMD11_RS23075 3f0d56d8ec754319a524476abdaee97e 141 Pfam PF02566 OsmC-like protein 44 136 1.0E-17 T 06-07-2017 IPR003718 OsmC/Ohr family SMD11_RS25745 a6e88509faaba882e12c595de0916ad3 288 SUPERFAMILY SSF52540 4 229 2.77E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25745 a6e88509faaba882e12c595de0916ad3 288 SMART SM00382 28 217 2.0E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS25745 a6e88509faaba882e12c595de0916ad3 288 Pfam PF00005 ABC transporter 20 167 1.5E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS25745 a6e88509faaba882e12c595de0916ad3 288 Gene3D G3DSA:3.40.50.300 4 235 9.6E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25745 a6e88509faaba882e12c595de0916ad3 288 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS00385 19570e040ae95cfc3cc8b99330554012 122 Pfam PF02152 Dihydroneopterin aldolase 7 115 2.2E-30 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD11_RS00385 19570e040ae95cfc3cc8b99330554012 122 TIGRFAM TIGR00526 folB_dom: FolB domain 5 118 2.2E-27 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD11_RS00385 19570e040ae95cfc3cc8b99330554012 122 Gene3D G3DSA:3.30.1130.10 3 117 3.6E-36 T 06-07-2017 SMD11_RS00385 19570e040ae95cfc3cc8b99330554012 122 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 5 116 4.7E-24 T 06-07-2017 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD11_RS00385 19570e040ae95cfc3cc8b99330554012 122 SMART SM00905 7 117 2.2E-40 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD11_RS00385 19570e040ae95cfc3cc8b99330554012 122 SUPERFAMILY SSF55620 2 117 1.0E-32 T 06-07-2017 SMD11_RS16265 1ccf8c18d8d3b378956e8f3b50c84bf8 675 SUPERFAMILY SSF55785 28 122 6.43E-11 T 06-07-2017 IPR000014 PAS domain SMD11_RS16265 1ccf8c18d8d3b378956e8f3b50c84bf8 675 SUPERFAMILY SSF55785 137 241 3.84E-19 T 06-07-2017 IPR000014 PAS domain SMD11_RS16265 1ccf8c18d8d3b378956e8f3b50c84bf8 675 Gene3D G3DSA:3.30.450.20 135 240 1.8E-19 T 06-07-2017 SMD11_RS16265 1ccf8c18d8d3b378956e8f3b50c84bf8 675 Gene3D G3DSA:3.30.450.20 30 124 5.0E-9 T 06-07-2017 SMD11_RS16265 1ccf8c18d8d3b378956e8f3b50c84bf8 675 Pfam PF08448 PAS fold 141 250 9.8E-21 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS16265 1ccf8c18d8d3b378956e8f3b50c84bf8 675 SUPERFAMILY SSF55781 382 440 1.62E-5 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS16265 1ccf8c18d8d3b378956e8f3b50c84bf8 675 Pfam PF13426 PAS domain 33 69 0.014 T 06-07-2017 IPR000014 PAS domain SMD11_RS16265 1ccf8c18d8d3b378956e8f3b50c84bf8 675 SMART SM00331 461 672 6.0E-39 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS16265 1ccf8c18d8d3b378956e8f3b50c84bf8 675 SMART SM00091 135 201 3.8E-7 T 06-07-2017 IPR000014 PAS domain SMD11_RS16265 1ccf8c18d8d3b378956e8f3b50c84bf8 675 SMART SM00091 20 89 0.0033 T 06-07-2017 IPR000014 PAS domain SMD11_RS16265 1ccf8c18d8d3b378956e8f3b50c84bf8 675 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 137 251 2.6E-12 T 06-07-2017 IPR000014 PAS domain SMD11_RS16265 1ccf8c18d8d3b378956e8f3b50c84bf8 675 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 32 114 5.4E-7 T 06-07-2017 IPR000014 PAS domain SMD11_RS16265 1ccf8c18d8d3b378956e8f3b50c84bf8 675 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 488 671 6.8E-46 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS16265 1ccf8c18d8d3b378956e8f3b50c84bf8 675 Gene3D G3DSA:3.30.450.40 269 438 2.3E-14 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS16265 1ccf8c18d8d3b378956e8f3b50c84bf8 675 SUPERFAMILY SSF81606 477 669 1.46E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS28925 4cc6e8ac508b7d52b3440917cb9d6937 711 Gene3D G3DSA:3.40.50.10320 203 279 5.9E-15 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD11_RS28925 4cc6e8ac508b7d52b3440917cb9d6937 711 Gene3D G3DSA:3.40.50.10320 53 156 5.9E-15 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD11_RS28925 4cc6e8ac508b7d52b3440917cb9d6937 711 SUPERFAMILY SSF89372 479 705 2.75E-13 T 06-07-2017 SMD11_RS28925 4cc6e8ac508b7d52b3440917cb9d6937 711 SUPERFAMILY SSF89372 376 518 2.62E-6 T 06-07-2017 SMD11_RS28925 4cc6e8ac508b7d52b3440917cb9d6937 711 Pfam PF02585 GlcNAc-PI de-N-acetylase 55 274 1.9E-16 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SMD11_RS28925 4cc6e8ac508b7d52b3440917cb9d6937 711 SUPERFAMILY SSF102588 159 285 1.31E-13 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD11_RS28925 4cc6e8ac508b7d52b3440917cb9d6937 711 SUPERFAMILY SSF102588 52 127 1.31E-13 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD11_RS32220 d8ee69d2d248440d54b08c60b5cac2b2 263 Pfam PF01636 Phosphotransferase enzyme family 36 184 5.4E-10 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase SMD11_RS32220 d8ee69d2d248440d54b08c60b5cac2b2 263 Gene3D G3DSA:3.90.1200.10 31 202 3.1E-16 T 06-07-2017 SMD11_RS32220 d8ee69d2d248440d54b08c60b5cac2b2 263 SUPERFAMILY SSF56112 19 208 1.15E-19 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS34490 8c706542b3b26397817fe9e90b060bf9 421 SMART SM01192 128 409 4.1E-15 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS34490 8c706542b3b26397817fe9e90b060bf9 421 PIRSF PIRSF001400 7 395 1.7E-42 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS34490 8c706542b3b26397817fe9e90b060bf9 421 SUPERFAMILY SSF54826 11 115 1.56E-5 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS34490 8c706542b3b26397817fe9e90b060bf9 421 SUPERFAMILY SSF51604 129 393 4.35E-37 T 06-07-2017 IPR029065 Enolase C-terminal domain-like SMD11_RS34490 8c706542b3b26397817fe9e90b060bf9 421 Gene3D G3DSA:3.20.20.120 127 393 1.7E-36 T 06-07-2017 IPR029065 Enolase C-terminal domain-like SMD11_RS34490 8c706542b3b26397817fe9e90b060bf9 421 Pfam PF00113 Enolase, C-terminal TIM barrel domain 134 393 3.8E-26 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS34490 8c706542b3b26397817fe9e90b060bf9 421 ProSitePatterns PS00164 Enolase signature. 321 334 - T 06-07-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS34490 8c706542b3b26397817fe9e90b060bf9 421 PRINTS PR00148 Enolase signature 350 367 1.8E-7 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS34490 8c706542b3b26397817fe9e90b060bf9 421 PRINTS PR00148 Enolase signature 96 112 1.8E-7 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS34490 8c706542b3b26397817fe9e90b060bf9 421 PRINTS PR00148 Enolase signature 321 335 1.8E-7 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SMD11_RS02960 beee1d8566b0a43f0a6e7de5323cfa1e 275 SUPERFAMILY SSF51569 15 268 4.19E-38 T 06-07-2017 SMD11_RS02960 beee1d8566b0a43f0a6e7de5323cfa1e 275 PIRSF PIRSF001365 12 268 5.7E-37 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS02960 beee1d8566b0a43f0a6e7de5323cfa1e 275 Pfam PF00701 Dihydrodipicolinate synthetase family 16 226 8.7E-20 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS02960 beee1d8566b0a43f0a6e7de5323cfa1e 275 Gene3D G3DSA:3.20.20.70 12 251 6.0E-46 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS02960 beee1d8566b0a43f0a6e7de5323cfa1e 275 SMART SM01130 15 275 1.8E-18 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS18585 c243726b4cbcff7fbee50e1a591787ca 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 3.8E-24 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 SMD11_RS18585 c243726b4cbcff7fbee50e1a591787ca 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 19.774 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 SMD11_RS20680 c9fdd278712da5c9a9580d49f98c1b5e 178 Gene3D G3DSA:2.60.120.10 44 154 4.0E-18 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS20680 c9fdd278712da5c9a9580d49f98c1b5e 178 Pfam PF05995 Cysteine dioxygenase type I 17 153 5.8E-24 T 06-07-2017 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 SMD11_RS20680 c9fdd278712da5c9a9580d49f98c1b5e 178 SUPERFAMILY SSF51182 23 153 1.44E-30 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS10950 d7727b8aa19e1a5093a283c7424042e3 192 SUPERFAMILY SSF52540 14 188 4.24E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10950 d7727b8aa19e1a5093a283c7424042e3 192 Pfam PF03029 Conserved hypothetical ATP binding protein 20 187 5.8E-24 T 06-07-2017 IPR004130 GPN-loop GTPase SMD11_RS10950 d7727b8aa19e1a5093a283c7424042e3 192 Gene3D G3DSA:3.40.50.300 14 183 1.2E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28070 39ae03f63526e11a4acc5b50be8c0a3f 158 Pfam PF05331 Protein of unknown function (DUF742) 36 158 7.6E-35 T 06-07-2017 IPR007995 Protein of unknown function DUF742 SMD11_RS28070 39ae03f63526e11a4acc5b50be8c0a3f 158 Gene3D G3DSA:1.10.10.10 85 136 3.9E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04970 072b4e2c5ecffbc55e81cc9af0716d84 647 Gene3D G3DSA:3.40.50.300 241 302 7.1E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04970 072b4e2c5ecffbc55e81cc9af0716d84 647 Gene3D G3DSA:3.40.50.300 482 566 7.1E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04970 072b4e2c5ecffbc55e81cc9af0716d84 647 Gene3D G3DSA:3.40.50.300 5 103 7.1E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04970 072b4e2c5ecffbc55e81cc9af0716d84 647 Gene3D G3DSA:1.10.287.510 303 412 3.6E-6 T 06-07-2017 SMD11_RS04970 072b4e2c5ecffbc55e81cc9af0716d84 647 Pfam PF12532 Protein of unknown function (DUF3732) 462 634 3.2E-48 T 06-07-2017 IPR022205 Protein of unknown function DUF3732 SMD11_RS18140 1819790dbe2897b5d9fc7a4219faa909 635 SUPERFAMILY SSF55874 534 628 4.73E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS18140 1819790dbe2897b5d9fc7a4219faa909 635 SMART SM00331 286 496 2.4E-39 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS18140 1819790dbe2897b5d9fc7a4219faa909 635 Pfam PF13581 Histidine kinase-like ATPase domain 520 611 1.5E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS18140 1819790dbe2897b5d9fc7a4219faa909 635 Gene3D G3DSA:3.30.450.20 95 177 1.1E-6 T 06-07-2017 SMD11_RS18140 1819790dbe2897b5d9fc7a4219faa909 635 SUPERFAMILY SSF81606 296 495 5.23E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS18140 1819790dbe2897b5d9fc7a4219faa909 635 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 313 496 1.8E-48 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS18110 d32dc2e3414aab1a3797a2ed180f2f99 405 Gene3D G3DSA:3.30.9.10 91 141 3.8E-9 T 06-07-2017 SMD11_RS18110 d32dc2e3414aab1a3797a2ed180f2f99 405 SUPERFAMILY SSF51905 5 221 5.5E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18110 d32dc2e3414aab1a3797a2ed180f2f99 405 Gene3D G3DSA:3.50.50.60 5 88 4.2E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18110 d32dc2e3414aab1a3797a2ed180f2f99 405 Gene3D G3DSA:3.50.50.60 142 249 4.2E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18110 d32dc2e3414aab1a3797a2ed180f2f99 405 Pfam PF01266 FAD dependent oxidoreductase 7 395 1.7E-66 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD11_RS25685 648c895ad377c822694cd8de35923b32 260 Pfam PF07070 SpoOM protein 3 216 2.1E-79 T 06-07-2017 IPR009776 Sporulation stage 0, protein M SMD11_RS10215 356f66a4aac4cd15f63681be2bf6ca58 388 Gene3D G3DSA:2.30.30.280 234 294 6.9E-16 T 06-07-2017 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 SMD11_RS10215 356f66a4aac4cd15f63681be2bf6ca58 388 Gene3D G3DSA:3.40.50.620 17 231 1.7E-76 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS10215 356f66a4aac4cd15f63681be2bf6ca58 388 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 20 375 36.282 T 06-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 SMD11_RS10215 356f66a4aac4cd15f63681be2bf6ca58 388 Pfam PF03054 tRNA methyl transferase 21 374 2.3E-118 T 06-07-2017 SMD11_RS10215 356f66a4aac4cd15f63681be2bf6ca58 388 SUPERFAMILY SSF52402 21 264 2.87E-46 T 06-07-2017 SMD11_RS10215 356f66a4aac4cd15f63681be2bf6ca58 388 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 22 374 3.4E-87 T 06-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 SMD11_RS10215 356f66a4aac4cd15f63681be2bf6ca58 388 Gene3D G3DSA:2.40.30.10 301 379 1.2E-17 T 06-07-2017 SMD11_RS07755 e77b94bfbb256b8999cbc40927647913 136 Gene3D G3DSA:3.10.129.10 18 127 1.1E-24 T 06-07-2017 IPR029069 HotDog domain SMD11_RS07755 e77b94bfbb256b8999cbc40927647913 136 Pfam PF07977 FabA-like domain 17 103 6.9E-13 T 06-07-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 SMD11_RS07755 e77b94bfbb256b8999cbc40927647913 136 SUPERFAMILY SSF54637 17 133 3.9E-23 T 06-07-2017 IPR029069 HotDog domain SMD11_RS14260 626e078f9ed8d1fde8a410e6d095c257 307 PIRSF PIRSF021524 9 307 5.8E-110 T 06-07-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 SMD11_RS14260 626e078f9ed8d1fde8a410e6d095c257 307 SUPERFAMILY SSF55729 15 303 2.48E-50 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS14260 626e078f9ed8d1fde8a410e6d095c257 307 Pfam PF00583 Acetyltransferase (GNAT) family 68 136 3.5E-6 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS14260 626e078f9ed8d1fde8a410e6d095c257 307 Pfam PF00583 Acetyltransferase (GNAT) family 217 294 3.5E-15 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS14260 626e078f9ed8d1fde8a410e6d095c257 307 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 18 303 2.1E-114 T 06-07-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 SMD11_RS14260 626e078f9ed8d1fde8a410e6d095c257 307 Gene3D G3DSA:3.40.630.30 164 303 1.3E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS14260 626e078f9ed8d1fde8a410e6d095c257 307 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 14 305 36.263 T 06-07-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 SMD11_RS14260 626e078f9ed8d1fde8a410e6d095c257 307 Gene3D G3DSA:3.40.630.30 19 136 4.1E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS34510 473f5421c286617b0b9816984d505bea 85 Gene3D G3DSA:1.10.1740.10 15 61 1.3E-4 T 06-07-2017 SMD11_RS25670 bc496a1f32900dcd2c86b3cfb8b86c47 179 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 41 170 5.2E-41 T 06-07-2017 IPR005247 YbhB/YbcL SMD11_RS25670 bc496a1f32900dcd2c86b3cfb8b86c47 179 Pfam PF01161 Phosphatidylethanolamine-binding protein 40 173 4.5E-38 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein SMD11_RS25670 bc496a1f32900dcd2c86b3cfb8b86c47 179 SUPERFAMILY SSF49777 20 174 1.2E-50 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein SMD11_RS25670 bc496a1f32900dcd2c86b3cfb8b86c47 179 Gene3D G3DSA:3.90.280.10 19 174 3.8E-54 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein SMD11_RS03070 b276a6889e99c6e781da4ad7c271bc46 764 SUPERFAMILY SSF55469 402 509 3.01E-9 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS03070 b276a6889e99c6e781da4ad7c271bc46 764 Pfam PF00899 ThiF family 125 353 6.7E-14 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SMD11_RS03070 b276a6889e99c6e781da4ad7c271bc46 764 Gene3D G3DSA:3.40.50.720 114 294 1.5E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03070 b276a6889e99c6e781da4ad7c271bc46 764 Gene3D G3DSA:3.40.50.720 329 359 1.5E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03070 b276a6889e99c6e781da4ad7c271bc46 764 Gene3D G3DSA:3.40.109.30 419 486 8.1E-10 T 06-07-2017 SMD11_RS03070 b276a6889e99c6e781da4ad7c271bc46 764 Gene3D G3DSA:3.40.109.10 405 418 2.5E-15 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS03070 b276a6889e99c6e781da4ad7c271bc46 764 Gene3D G3DSA:3.40.109.10 613 755 2.5E-15 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS03070 b276a6889e99c6e781da4ad7c271bc46 764 Gene3D G3DSA:3.40.109.10 549 565 2.5E-15 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS03070 b276a6889e99c6e781da4ad7c271bc46 764 SUPERFAMILY SSF69572 110 278 1.83E-23 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 SMD11_RS14415 eff0801a67fb204232fabb6ad3fceb4a 90 Pfam PF11298 Protein of unknown function (DUF3099) 3 59 5.8E-7 T 06-07-2017 IPR021449 Protein of unknown function DUF3099 SMD11_RS28680 e86f7d6a49194b6588ca37df333675eb 276 SUPERFAMILY SSF53474 17 273 2.04E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28680 e86f7d6a49194b6588ca37df333675eb 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 7.1E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS28680 e86f7d6a49194b6588ca37df333675eb 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 7.1E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS28680 e86f7d6a49194b6588ca37df333675eb 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 7.1E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS28680 e86f7d6a49194b6588ca37df333675eb 276 Gene3D G3DSA:3.40.50.1820 17 273 5.1E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28680 e86f7d6a49194b6588ca37df333675eb 276 Pfam PF12697 Alpha/beta hydrolase family 31 269 4.6E-21 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS08080 e60b298d44d6e3c4b46de63193e71917 386 SUPERFAMILY SSF53383 17 367 3.99E-108 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS08080 e60b298d44d6e3c4b46de63193e71917 386 Gene3D G3DSA:3.40.640.10 3 243 8.1E-76 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS08080 e60b298d44d6e3c4b46de63193e71917 386 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 17 363 1.6E-119 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMD11_RS08080 e60b298d44d6e3c4b46de63193e71917 386 PIRSF PIRSF000390 2 370 1.2E-109 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMD11_RS08080 e60b298d44d6e3c4b46de63193e71917 386 Gene3D G3DSA:3.90.1150.10 245 367 6.2E-38 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS19865 aff84c34b47a8f1d429427170e58bf15 186 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 25 163 3.0E-29 T 06-07-2017 IPR001453 MoaB/Mog domain SMD11_RS19865 aff84c34b47a8f1d429427170e58bf15 186 Gene3D G3DSA:3.40.980.10 24 176 1.5E-49 T 06-07-2017 IPR001453 MoaB/Mog domain SMD11_RS19865 aff84c34b47a8f1d429427170e58bf15 186 SMART SM00852 28 170 2.9E-21 T 06-07-2017 IPR001453 MoaB/Mog domain SMD11_RS19865 aff84c34b47a8f1d429427170e58bf15 186 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 86 99 - T 06-07-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 SMD11_RS19865 aff84c34b47a8f1d429427170e58bf15 186 SUPERFAMILY SSF53218 24 174 3.93E-39 T 06-07-2017 IPR001453 MoaB/Mog domain SMD11_RS19865 aff84c34b47a8f1d429427170e58bf15 186 Pfam PF00994 Probable molybdopterin binding domain 29 168 1.3E-26 T 06-07-2017 IPR001453 MoaB/Mog domain SMD11_RS17090 bc26dce39bb44c682210a9c8c7251842 444 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 42 431 1.0E-133 T 06-07-2017 IPR018721 Protein of unknown function DUF2252 SMD11_RS01740 c66fc20c0ceb662aeb496a8d4cf05d23 175 Pfam PF13673 Acetyltransferase (GNAT) domain 57 152 7.2E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS01740 c66fc20c0ceb662aeb496a8d4cf05d23 175 SUPERFAMILY SSF55729 11 174 8.06E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS01740 c66fc20c0ceb662aeb496a8d4cf05d23 175 Gene3D G3DSA:3.40.630.30 11 174 1.4E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS17735 d00a967e4484ed900bf214ff64660074 179 SUPERFAMILY SSF53271 5 172 1.13E-35 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS17735 d00a967e4484ed900bf214ff64660074 179 Pfam PF00156 Phosphoribosyl transferase domain 63 168 2.0E-11 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMD11_RS17735 d00a967e4484ed900bf214ff64660074 179 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 13 166 1.6E-36 T 06-07-2017 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD11_RS17735 d00a967e4484ed900bf214ff64660074 179 Gene3D G3DSA:3.40.50.2020 4 175 2.2E-48 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS17735 d00a967e4484ed900bf214ff64660074 179 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 179 24.893 T 06-07-2017 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD11_RS20320 3e8e79d5cc2b9882dd4aba6e04062c96 438 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 162 406 9.8E-4 T 06-07-2017 IPR020803 Polyketide synthase, methyltransferase domain SMD11_RS20320 3e8e79d5cc2b9882dd4aba6e04062c96 438 Gene3D G3DSA:3.40.50.150 143 420 2.2E-94 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS20320 3e8e79d5cc2b9882dd4aba6e04062c96 438 Pfam PF02353 Mycolic acid cyclopropane synthetase 145 418 1.8E-91 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS20320 3e8e79d5cc2b9882dd4aba6e04062c96 438 SUPERFAMILY SSF53335 153 422 5.93E-78 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS20320 3e8e79d5cc2b9882dd4aba6e04062c96 438 PIRSF PIRSF003085 4 435 1.7E-129 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 SMD11_RS04900 92f3c93f57710b8194f8df5beb325258 396 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 104 169 5.0E-5 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS04900 92f3c93f57710b8194f8df5beb325258 396 Gene3D G3DSA:3.30.470.20 100 302 4.4E-20 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS04900 92f3c93f57710b8194f8df5beb325258 396 SUPERFAMILY SSF56059 86 303 7.6E-32 T 06-07-2017 SMD11_RS22300 f5203feb7fe09dc1f0b3cf7e9c5108c3 507 SUPERFAMILY SSF102735 47 174 2.62E-36 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SMD11_RS22300 f5203feb7fe09dc1f0b3cf7e9c5108c3 507 Pfam PF05697 Bacterial trigger factor protein (TF) 47 189 1.0E-41 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SMD11_RS22300 f5203feb7fe09dc1f0b3cf7e9c5108c3 507 Gene3D G3DSA:3.30.70.1050 47 163 4.4E-34 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SMD11_RS22300 f5203feb7fe09dc1f0b3cf7e9c5108c3 507 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 302 463 5.5E-39 T 06-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 SMD11_RS22300 f5203feb7fe09dc1f0b3cf7e9c5108c3 507 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 201 259 9.5E-8 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 SMD11_RS22300 f5203feb7fe09dc1f0b3cf7e9c5108c3 507 SUPERFAMILY SSF54534 177 287 8.45E-21 T 06-07-2017 SMD11_RS22300 f5203feb7fe09dc1f0b3cf7e9c5108c3 507 Hamap MF_00303 Trigger factor [tig]. 45 469 19.423 T 06-07-2017 IPR005215 Trigger factor GO:0015031 SMD11_RS22300 f5203feb7fe09dc1f0b3cf7e9c5108c3 507 Gene3D G3DSA:1.10.3120.10 255 438 2.7E-45 T 06-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 SMD11_RS22300 f5203feb7fe09dc1f0b3cf7e9c5108c3 507 TIGRFAM TIGR00115 tig: trigger factor 56 461 1.8E-122 T 06-07-2017 IPR005215 Trigger factor GO:0015031 SMD11_RS22300 f5203feb7fe09dc1f0b3cf7e9c5108c3 507 Gene3D G3DSA:3.10.50.40 200 254 1.7E-6 T 06-07-2017 SMD11_RS22300 f5203feb7fe09dc1f0b3cf7e9c5108c3 507 SUPERFAMILY SSF109998 289 478 1.96E-38 T 06-07-2017 IPR027304 Trigger factor/SurA domain SMD11_RS12175 f7064c6d009d8bb9b5b3d01cf88b221e 505 SUPERFAMILY SSF52266 73 354 1.07E-52 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS12175 f7064c6d009d8bb9b5b3d01cf88b221e 505 Pfam PF00652 Ricin-type beta-trefoil lectin domain 384 504 7.4E-21 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS12175 f7064c6d009d8bb9b5b3d01cf88b221e 505 SMART SM00458 380 504 4.4E-16 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS12175 f7064c6d009d8bb9b5b3d01cf88b221e 505 Gene3D G3DSA:2.80.10.50 381 504 1.3E-24 T 06-07-2017 SMD11_RS12175 f7064c6d009d8bb9b5b3d01cf88b221e 505 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 77 342 1.3E-15 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS12175 f7064c6d009d8bb9b5b3d01cf88b221e 505 SUPERFAMILY SSF50370 384 504 3.15E-28 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS12175 f7064c6d009d8bb9b5b3d01cf88b221e 505 Gene3D G3DSA:3.40.50.1110 71 351 6.8E-43 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS31390 156cb8945a5a83097bbc87aa2a29f4e5 507 SUPERFAMILY SSF103378 18 486 1.23E-112 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 SMD11_RS31390 156cb8945a5a83097bbc87aa2a29f4e5 507 Gene3D G3DSA:3.30.1330.120 288 427 5.8E-44 T 06-07-2017 SMD11_RS31390 156cb8945a5a83097bbc87aa2a29f4e5 507 Pfam PF03972 MmgE/PrpD family 20 475 1.1E-115 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 SMD11_RS29075 0bd7d3f3867400e8780f7c6f4fe479c0 516 Gene3D G3DSA:3.40.50.980 8 174 6.8E-25 T 06-07-2017 SMD11_RS29075 0bd7d3f3867400e8780f7c6f4fe479c0 516 ProSitePatterns PS00455 Putative AMP-binding domain signature. 161 172 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS29075 0bd7d3f3867400e8780f7c6f4fe479c0 516 SUPERFAMILY SSF56801 6 510 2.09E-114 T 06-07-2017 SMD11_RS29075 0bd7d3f3867400e8780f7c6f4fe479c0 516 Gene3D G3DSA:3.30.300.30 407 509 1.9E-31 T 06-07-2017 SMD11_RS29075 0bd7d3f3867400e8780f7c6f4fe479c0 516 Gene3D G3DSA:2.30.38.10 331 405 1.3E-11 T 06-07-2017 SMD11_RS29075 0bd7d3f3867400e8780f7c6f4fe479c0 516 Gene3D G3DSA:3.40.50.980 202 317 2.6E-27 T 06-07-2017 SMD11_RS29075 0bd7d3f3867400e8780f7c6f4fe479c0 516 Pfam PF00501 AMP-binding enzyme 11 411 5.1E-62 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS29075 0bd7d3f3867400e8780f7c6f4fe479c0 516 Pfam PF13193 AMP-binding enzyme C-terminal domain 420 498 5.6E-20 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS03880 db9676c622f88c12013bf7665b7d84f1 508 SMART SM00388 278 345 1.2E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS03880 db9676c622f88c12013bf7665b7d84f1 508 SUPERFAMILY SSF47384 261 345 3.34E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS03880 db9676c622f88c12013bf7665b7d84f1 508 SUPERFAMILY SSF55874 334 502 1.27E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS03880 db9676c622f88c12013bf7665b7d84f1 508 Pfam PF00672 HAMP domain 205 266 2.0E-16 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS03880 db9676c622f88c12013bf7665b7d84f1 508 Gene3D G3DSA:1.10.287.130 269 331 7.8E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS03880 db9676c622f88c12013bf7665b7d84f1 508 SUPERFAMILY SSF158472 218 267 1.44E-10 T 06-07-2017 SMD11_RS03880 db9676c622f88c12013bf7665b7d84f1 508 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 442 7.5E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS03880 db9676c622f88c12013bf7665b7d84f1 508 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 480 7.5E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS03880 db9676c622f88c12013bf7665b7d84f1 508 PRINTS PR00344 Bacterial sensor protein C-terminal signature 486 499 7.5E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS03880 db9676c622f88c12013bf7665b7d84f1 508 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 456 7.5E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS03880 db9676c622f88c12013bf7665b7d84f1 508 SMART SM00304 218 270 1.1E-17 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS03880 db9676c622f88c12013bf7665b7d84f1 508 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 386 501 5.8E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS03880 db9676c622f88c12013bf7665b7d84f1 508 Gene3D G3DSA:3.30.565.10 332 501 2.3E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS03880 db9676c622f88c12013bf7665b7d84f1 508 Pfam PF00512 His Kinase A (phospho-acceptor) domain 280 345 5.6E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS03880 db9676c622f88c12013bf7665b7d84f1 508 SMART SM00387 385 502 4.2E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS09350 2239ac6e8a2e4e5f35e1c6cb55831d1b 275 SUPERFAMILY SSF161098 16 267 1.21E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS09350 2239ac6e8a2e4e5f35e1c6cb55831d1b 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 262 6.6E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS09350 2239ac6e8a2e4e5f35e1c6cb55831d1b 275 Gene3D G3DSA:1.10.3720.10 22 274 9.1E-49 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS03760 2d126fdf08b317e963074f4c0a8c4928 1011 Gene3D G3DSA:3.20.110.10 207 524 1.0E-88 T 06-07-2017 IPR027291 Glycoside hydrolase 38/57, N-terminal domain SMD11_RS03760 2d126fdf08b317e963074f4c0a8c4928 1011 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 664 1007 7.6E-67 T 06-07-2017 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0006013|GO:0015923 SMD11_RS03760 2d126fdf08b317e963074f4c0a8c4928 1011 SUPERFAMILY SSF74650 666 1009 4.71E-68 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMD11_RS03760 2d126fdf08b317e963074f4c0a8c4928 1011 SUPERFAMILY SSF88713 252 520 1.78E-77 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS03760 2d126fdf08b317e963074f4c0a8c4928 1011 Gene3D G3DSA:1.20.1270.50 525 621 1.0E-22 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 SMD11_RS03760 2d126fdf08b317e963074f4c0a8c4928 1011 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 258 512 2.1E-84 T 06-07-2017 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 SMD11_RS03760 2d126fdf08b317e963074f4c0a8c4928 1011 SUPERFAMILY SSF88688 521 623 7.52E-27 T 06-07-2017 IPR028995 Glycoside hydrolase families 57/38, central domain SMD11_RS03760 2d126fdf08b317e963074f4c0a8c4928 1011 Pfam PF09261 Alpha mannosidase middle domain 522 599 2.3E-25 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 SMD11_RS03760 2d126fdf08b317e963074f4c0a8c4928 1011 SMART SM00872 522 600 9.4E-37 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 SMD11_RS06490 0aa12513deb1f429bb1db49f4f77b8c2 445 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 31 427 2.3E-190 T 06-07-2017 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 SMD11_RS06490 0aa12513deb1f429bb1db49f4f77b8c2 445 SMART SM00829 49 415 3.7E-11 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS06490 0aa12513deb1f429bb1db49f4f77b8c2 445 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 115 189 3.1E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS06490 0aa12513deb1f429bb1db49f4f77b8c2 445 Pfam PF00107 Zinc-binding dehydrogenase 236 380 1.8E-39 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS06490 0aa12513deb1f429bb1db49f4f77b8c2 445 Gene3D G3DSA:3.40.50.720 232 364 3.6E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06490 0aa12513deb1f429bb1db49f4f77b8c2 445 SUPERFAMILY SSF50129 49 230 1.94E-29 T 06-07-2017 IPR011032 GroES-like SMD11_RS06490 0aa12513deb1f429bb1db49f4f77b8c2 445 Gene3D G3DSA:3.90.180.10 43 231 1.7E-31 T 06-07-2017 IPR011032 GroES-like SMD11_RS06490 0aa12513deb1f429bb1db49f4f77b8c2 445 SUPERFAMILY SSF51735 198 394 8.82E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29105 08a41b38abb15c063d55f5e3903b13fd 320 Gene3D G3DSA:2.40.50.140 83 132 6.2E-4 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS29105 08a41b38abb15c063d55f5e3903b13fd 320 SUPERFAMILY SSF50249 3 136 4.8E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS29105 08a41b38abb15c063d55f5e3903b13fd 320 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 227 293 2.4E-13 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal SMD11_RS29105 08a41b38abb15c063d55f5e3903b13fd 320 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 66 127 1.5E-9 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal SMD11_RS29105 08a41b38abb15c063d55f5e3903b13fd 320 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 190 221 2.7E-9 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal SMD11_RS29105 08a41b38abb15c063d55f5e3903b13fd 320 SUPERFAMILY SSF50249 164 295 9.25E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS10670 6d8a8766acc0c355f565c89037df7be9 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 2 386 2.4E-137 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS10670 6d8a8766acc0c355f565c89037df7be9 391 SUPERFAMILY SSF53901 1 266 3.76E-83 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS10670 6d8a8766acc0c355f565c89037df7be9 391 Pfam PF02803 Thiolase, C-terminal domain 267 387 2.6E-44 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD11_RS10670 6d8a8766acc0c355f565c89037df7be9 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 80 98 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 SMD11_RS10670 6d8a8766acc0c355f565c89037df7be9 391 Gene3D G3DSA:3.40.47.10 190 272 4.4E-72 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS10670 6d8a8766acc0c355f565c89037df7be9 391 Gene3D G3DSA:3.40.47.10 1 119 4.4E-72 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS10670 6d8a8766acc0c355f565c89037df7be9 391 ProSitePatterns PS00099 Thiolases active site. 370 383 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SMD11_RS10670 6d8a8766acc0c355f565c89037df7be9 391 PIRSF PIRSF000429 1 390 2.8E-119 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS10670 6d8a8766acc0c355f565c89037df7be9 391 Gene3D G3DSA:3.40.47.10 138 189 1.1E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS10670 6d8a8766acc0c355f565c89037df7be9 391 Gene3D G3DSA:3.40.47.10 273 388 1.1E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS10670 6d8a8766acc0c355f565c89037df7be9 391 SUPERFAMILY SSF53901 268 387 2.92E-36 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS10670 6d8a8766acc0c355f565c89037df7be9 391 ProSitePatterns PS00737 Thiolases signature 2. 335 351 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMD11_RS10670 6d8a8766acc0c355f565c89037df7be9 391 Pfam PF00108 Thiolase, N-terminal domain 1 258 8.1E-95 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD11_RS07880 2d957b60e647a11d6325cc9e7067309c 399 SUPERFAMILY SSF53383 117 396 1.17E-30 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS07880 2d957b60e647a11d6325cc9e7067309c 399 Pfam PF00155 Aminotransferase class I and II 100 381 5.6E-14 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS07880 2d957b60e647a11d6325cc9e7067309c 399 Gene3D G3DSA:3.40.640.10 92 261 1.5E-14 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS07880 2d957b60e647a11d6325cc9e7067309c 399 Gene3D G3DSA:3.90.1150.10 262 395 6.3E-14 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS29485 767168678781c1c4e24c628e5cfd375f 382 Gene3D G3DSA:3.40.640.10 43 247 1.9E-41 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS29485 767168678781c1c4e24c628e5cfd375f 382 SUPERFAMILY SSF53383 19 381 1.77E-77 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS29485 767168678781c1c4e24c628e5cfd375f 382 Pfam PF00155 Aminotransferase class I and II 99 376 4.0E-29 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS29485 767168678781c1c4e24c628e5cfd375f 382 Gene3D G3DSA:3.90.1150.10 248 381 2.8E-38 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS18640 49958a7869a1dab56e2fa394df8ee8d0 319 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS18640 49958a7869a1dab56e2fa394df8ee8d0 319 Gene3D G3DSA:3.40.50.300 5 232 3.2E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18640 49958a7869a1dab56e2fa394df8ee8d0 319 SMART SM00382 33 217 7.2E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS18640 49958a7869a1dab56e2fa394df8ee8d0 319 Pfam PF00005 ABC transporter 25 169 1.1E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS18640 49958a7869a1dab56e2fa394df8ee8d0 319 SUPERFAMILY SSF52540 3 234 2.62E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28570 3bbb3dbf6dac18266bd44a671c04560d 91 SUPERFAMILY SSF50022 10 75 5.11E-18 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS28570 3bbb3dbf6dac18266bd44a671c04560d 91 Pfam PF00355 Rieske [2Fe-2S] domain 23 76 5.5E-11 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS28570 3bbb3dbf6dac18266bd44a671c04560d 91 Gene3D G3DSA:2.102.10.10 13 75 9.1E-18 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS09720 dafd51d90a42c2b48198c98bbc2a8a11 199 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 119 125 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMD11_RS09720 dafd51d90a42c2b48198c98bbc2a8a11 199 SUPERFAMILY SSF53335 2 181 7.78E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS09720 dafd51d90a42c2b48198c98bbc2a8a11 199 Gene3D G3DSA:3.40.50.150 1 186 4.9E-58 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS09720 dafd51d90a42c2b48198c98bbc2a8a11 199 PIRSF PIRSF004553 1 187 9.1E-50 T 06-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD11_RS09720 dafd51d90a42c2b48198c98bbc2a8a11 199 Pfam PF03602 Conserved hypothetical protein 95 2 183 4.3E-52 T 06-07-2017 SMD11_RS09720 dafd51d90a42c2b48198c98bbc2a8a11 199 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 183 5.3E-44 T 06-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD11_RS03595 274ee15449ed2a17857245228c277783 837 SMART SM00487 27 212 1.2E-16 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS03595 274ee15449ed2a17857245228c277783 837 SUPERFAMILY SSF52540 44 250 3.81E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03595 274ee15449ed2a17857245228c277783 837 SUPERFAMILY SSF52540 283 375 3.81E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03595 274ee15449ed2a17857245228c277783 837 Gene3D G3DSA:3.40.50.300 219 377 7.5E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03595 274ee15449ed2a17857245228c277783 837 Pfam PF12029 Domain of unknown function (DUF3516) 374 834 1.9E-218 T 06-07-2017 IPR021904 Protein of unknown function DUF3516 SMD11_RS03595 274ee15449ed2a17857245228c277783 837 Pfam PF00270 DEAD/DEAH box helicase 33 180 5.4E-10 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD11_RS03595 274ee15449ed2a17857245228c277783 837 Pfam PF00271 Helicase conserved C-terminal domain 281 363 8.1E-6 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS03595 274ee15449ed2a17857245228c277783 837 Gene3D G3DSA:3.40.50.300 17 193 1.9E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03595 274ee15449ed2a17857245228c277783 837 SMART SM00490 277 363 2.5E-12 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS03405 1428a10d2f60df6097d8aa5227fbb747 125 Gene3D G3DSA:1.25.40.10 13 122 2.1E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS03405 1428a10d2f60df6097d8aa5227fbb747 125 SUPERFAMILY SSF48452 23 122 5.52E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS03405 1428a10d2f60df6097d8aa5227fbb747 125 Pfam PF14559 Tetratricopeptide repeat 31 94 1.7E-8 T 06-07-2017 SMD11_RS34595 86835951ee008f4e678c03f88e0cbe1f 294 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 76 91 - T 06-07-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 SMD11_RS34595 86835951ee008f4e678c03f88e0cbe1f 294 Gene3D G3DSA:3.40.50.150 2 165 4.0E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS34595 86835951ee008f4e678c03f88e0cbe1f 294 SUPERFAMILY SSF53335 4 122 1.34E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS34595 86835951ee008f4e678c03f88e0cbe1f 294 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 3 120 4.4E-24 T 06-07-2017 SMD11_RS25020 435e56f537f909708d5dd3d052c753ec 190 SUPERFAMILY SSF46767 104 184 3.79E-27 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS25020 435e56f537f909708d5dd3d052c753ec 190 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 104 182 1.8E-29 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS25020 435e56f537f909708d5dd3d052c753ec 190 Gene3D G3DSA:3.30.160.70 17 97 6.9E-6 T 06-07-2017 SMD11_RS25020 435e56f537f909708d5dd3d052c753ec 190 Gene3D G3DSA:1.10.10.10 103 184 2.7E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS25020 435e56f537f909708d5dd3d052c753ec 190 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 104 184 4.6E-29 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS25020 435e56f537f909708d5dd3d052c753ec 190 SUPERFAMILY SSF53155 16 100 1.43E-11 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS25020 435e56f537f909708d5dd3d052c753ec 190 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 153 159 - T 06-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS25020 435e56f537f909708d5dd3d052c753ec 190 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 15 185 34.925 T 06-07-2017 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 SMD11_RS28200 4473322a379a31238caf3f6750282e69 963 Gene3D G3DSA:3.40.640.10 95 310 6.2E-16 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS28200 4473322a379a31238caf3f6750282e69 963 Gene3D G3DSA:3.40.640.10 508 746 7.6E-40 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS28200 4473322a379a31238caf3f6750282e69 963 Pfam PF02347 Glycine cleavage system P-protein 19 447 2.4E-176 T 06-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SMD11_RS28200 4473322a379a31238caf3f6750282e69 963 Pfam PF02347 Glycine cleavage system P-protein 457 739 6.5E-10 T 06-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SMD11_RS28200 4473322a379a31238caf3f6750282e69 963 SUPERFAMILY SSF53383 481 893 1.53E-97 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS28200 4473322a379a31238caf3f6750282e69 963 SUPERFAMILY SSF53383 934 957 1.53E-97 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS28200 4473322a379a31238caf3f6750282e69 963 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 20 955 0.0 T 06-07-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SMD11_RS28200 4473322a379a31238caf3f6750282e69 963 SUPERFAMILY SSF53383 20 447 1.48E-100 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS28200 4473322a379a31238caf3f6750282e69 963 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 11 961 25.731 T 06-07-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 SMD11_RS15065 594c806b4164e89573a9c80b3df22b99 111 Gene3D G3DSA:3.30.40.10 23 104 9.9E-22 T 06-07-2017 IPR013083 Zinc finger, RING/FYVE/PHD-type SMD11_RS15065 594c806b4164e89573a9c80b3df22b99 111 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 42 104 2.0E-12 T 06-07-2017 IPR001607 Zinc finger, UBP-type GO:0008270 SMD11_RS15065 594c806b4164e89573a9c80b3df22b99 111 SUPERFAMILY SSF57850 24 106 3.41E-24 T 06-07-2017 SMD11_RS22900 1b38a9af513bddd19ecc01b873748dc0 214 Pfam PF00072 Response regulator receiver domain 4 108 6.2E-17 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS22900 1b38a9af513bddd19ecc01b873748dc0 214 SUPERFAMILY SSF52172 2 148 6.26E-22 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS22900 1b38a9af513bddd19ecc01b873748dc0 214 Gene3D G3DSA:3.40.50.2300 2 151 1.2E-26 T 06-07-2017 SMD11_RS22900 1b38a9af513bddd19ecc01b873748dc0 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 194 1.5E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS22900 1b38a9af513bddd19ecc01b873748dc0 214 Gene3D G3DSA:1.10.10.10 152 211 1.9E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS22900 1b38a9af513bddd19ecc01b873748dc0 214 SMART SM00448 1 120 1.0E-10 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS22900 1b38a9af513bddd19ecc01b873748dc0 214 SMART SM00421 147 210 1.1E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS22900 1b38a9af513bddd19ecc01b873748dc0 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 3.3E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS22900 1b38a9af513bddd19ecc01b873748dc0 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 3.3E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS22900 1b38a9af513bddd19ecc01b873748dc0 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 3.3E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS22900 1b38a9af513bddd19ecc01b873748dc0 214 SUPERFAMILY SSF46894 135 195 5.1E-15 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS08775 c0d30cbc44d97169a0450dce495828af 218 Gene3D G3DSA:1.10.10.60 27 74 3.3E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS08775 c0d30cbc44d97169a0450dce495828af 218 SUPERFAMILY SSF46689 28 89 3.29E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS08775 c0d30cbc44d97169a0450dce495828af 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 46 81 1.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS08775 c0d30cbc44d97169a0450dce495828af 218 SUPERFAMILY SSF48498 95 212 8.9E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS08775 c0d30cbc44d97169a0450dce495828af 218 Gene3D G3DSA:1.10.357.10 77 214 2.2E-38 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS08775 c0d30cbc44d97169a0450dce495828af 218 Pfam PF16859 Bacterial transcriptional repressor C-terminal 94 204 3.9E-28 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS11070 6bb5322f934bd1d3d40cb6acdc30474c 324 SUPERFAMILY SSF46785 10 104 2.24E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11070 6bb5322f934bd1d3d40cb6acdc30474c 324 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 8.1E-22 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal SMD11_RS11070 6bb5322f934bd1d3d40cb6acdc30474c 324 Gene3D G3DSA:1.10.10.10 4 98 9.5E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21120 22b87dd62642e57ff5d760bb2a384315 213 SMART SM00346 6 93 8.5E-16 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS21120 22b87dd62642e57ff5d760bb2a384315 213 Gene3D G3DSA:3.30.450.40 153 212 1.5E-5 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS21120 22b87dd62642e57ff5d760bb2a384315 213 Gene3D G3DSA:3.30.450.40 80 148 2.9E-13 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS21120 22b87dd62642e57ff5d760bb2a384315 213 Gene3D G3DSA:1.10.10.10 5 76 7.0E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21120 22b87dd62642e57ff5d760bb2a384315 213 SUPERFAMILY SSF46785 7 76 9.84E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21120 22b87dd62642e57ff5d760bb2a384315 213 SUPERFAMILY SSF55781 67 212 6.21E-19 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS21120 22b87dd62642e57ff5d760bb2a384315 213 Pfam PF09339 IclR helix-turn-helix domain 8 58 2.2E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS12025 12adf34ba79eddc4909ae860c5b594fb 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 307 9.5E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS12025 12adf34ba79eddc4909ae860c5b594fb 308 SUPERFAMILY SSF161098 91 289 1.96E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS12025 12adf34ba79eddc4909ae860c5b594fb 308 Gene3D G3DSA:1.10.3720.10 90 303 7.0E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS27235 ce8f1e06596ff6980f41128ad0c88001 420 Gene3D G3DSA:3.40.50.800 325 415 7.3E-28 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS27235 ce8f1e06596ff6980f41128ad0c88001 420 Pfam PF13393 Histidyl-tRNA synthetase 9 309 4.8E-41 T 06-07-2017 SMD11_RS27235 ce8f1e06596ff6980f41128ad0c88001 420 Gene3D G3DSA:3.30.930.10 219 319 1.2E-80 T 06-07-2017 SMD11_RS27235 ce8f1e06596ff6980f41128ad0c88001 420 Gene3D G3DSA:3.30.930.10 3 185 1.2E-80 T 06-07-2017 SMD11_RS27235 ce8f1e06596ff6980f41128ad0c88001 420 Pfam PF03129 Anticodon binding domain 328 417 2.1E-11 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS27235 ce8f1e06596ff6980f41128ad0c88001 420 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 407 1.5E-132 T 06-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 SMD11_RS27235 ce8f1e06596ff6980f41128ad0c88001 420 SUPERFAMILY SSF55681 4 315 7.57E-83 T 06-07-2017 SMD11_RS27235 ce8f1e06596ff6980f41128ad0c88001 420 SUPERFAMILY SSF52954 325 416 1.8E-22 T 06-07-2017 IPR004154 Anticodon-binding SMD11_RS27235 ce8f1e06596ff6980f41128ad0c88001 420 PIRSF PIRSF001549 1 418 3.4E-102 T 06-07-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 SMD11_RS27235 ce8f1e06596ff6980f41128ad0c88001 420 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 417 30.397 T 06-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 SMD11_RS30890 d6803409e797870bff95589bcf9e2ed0 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 1.3E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS30890 d6803409e797870bff95589bcf9e2ed0 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 424 1.3E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS30890 d6803409e797870bff95589bcf9e2ed0 468 Pfam PF00672 HAMP domain 165 232 7.3E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS30890 d6803409e797870bff95589bcf9e2ed0 468 SMART SM00387 341 446 1.5E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS30890 d6803409e797870bff95589bcf9e2ed0 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 286 9.1E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS30890 d6803409e797870bff95589bcf9e2ed0 468 SUPERFAMILY SSF55874 305 442 1.31E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS30890 d6803409e797870bff95589bcf9e2ed0 468 SUPERFAMILY SSF158472 185 234 5.36E-5 T 06-07-2017 SMD11_RS30890 d6803409e797870bff95589bcf9e2ed0 468 SMART SM00304 184 236 2.3E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS30890 d6803409e797870bff95589bcf9e2ed0 468 Gene3D G3DSA:3.30.565.10 305 444 1.1E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS30890 d6803409e797870bff95589bcf9e2ed0 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 444 4.3E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS30890 d6803409e797870bff95589bcf9e2ed0 468 SUPERFAMILY SSF47384 221 288 8.83E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS30890 d6803409e797870bff95589bcf9e2ed0 468 Gene3D G3DSA:1.10.287.130 227 288 4.3E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS30890 d6803409e797870bff95589bcf9e2ed0 468 SMART SM00388 237 295 8.6E-6 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS28895 e8906f11370a06f2068764fda9dfc3a9 974 SUPERFAMILY SSF46894 877 939 6.12E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS28895 e8906f11370a06f2068764fda9dfc3a9 974 Gene3D G3DSA:1.25.40.10 555 859 3.1E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS28895 e8906f11370a06f2068764fda9dfc3a9 974 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 901 917 2.1E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28895 e8906f11370a06f2068764fda9dfc3a9 974 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 917 929 2.1E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28895 e8906f11370a06f2068764fda9dfc3a9 974 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 887 901 2.1E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28895 e8906f11370a06f2068764fda9dfc3a9 974 SUPERFAMILY SSF48452 602 775 4.47E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS28895 e8906f11370a06f2068764fda9dfc3a9 974 SMART SM00421 884 941 2.1E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28895 e8906f11370a06f2068764fda9dfc3a9 974 Pfam PF00196 Bacterial regulatory proteins, luxR family 885 937 1.0E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28895 e8906f11370a06f2068764fda9dfc3a9 974 ProSitePatterns PS00622 LuxR-type HTH domain signature. 901 928 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28895 e8906f11370a06f2068764fda9dfc3a9 974 Pfam PF13191 AAA ATPase domain 15 164 3.4E-16 T 06-07-2017 SMD11_RS28895 e8906f11370a06f2068764fda9dfc3a9 974 SUPERFAMILY SSF52540 15 96 2.23E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28895 e8906f11370a06f2068764fda9dfc3a9 974 SUPERFAMILY SSF52540 125 240 2.23E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28895 e8906f11370a06f2068764fda9dfc3a9 974 Gene3D G3DSA:1.10.10.10 880 937 9.9E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08450 9d09668ed284de9f5981a0364291fb37 654 SMART SM00065 73 224 3.0E-19 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS08450 9d09668ed284de9f5981a0364291fb37 654 Pfam PF13556 PucR C-terminal helix-turn-helix domain 569 627 4.3E-21 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain SMD11_RS08450 9d09668ed284de9f5981a0364291fb37 654 Gene3D G3DSA:3.30.450.40 48 226 3.2E-30 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS08450 9d09668ed284de9f5981a0364291fb37 654 Pfam PF13185 GAF domain 72 215 2.0E-17 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS08450 9d09668ed284de9f5981a0364291fb37 654 SUPERFAMILY SSF55781 73 223 1.5E-24 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS29140 333eeee02c0b459f00a8363b9b3e5def 205 SUPERFAMILY SSF48498 89 203 6.82E-22 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS29140 333eeee02c0b459f00a8363b9b3e5def 205 Pfam PF13977 Bacterial transcriptional repressor 89 201 4.8E-24 T 06-07-2017 SMD11_RS29140 333eeee02c0b459f00a8363b9b3e5def 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 57 1.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS29140 333eeee02c0b459f00a8363b9b3e5def 205 SUPERFAMILY SSF46689 6 78 2.31E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS29140 333eeee02c0b459f00a8363b9b3e5def 205 Gene3D G3DSA:1.10.357.10 1 201 2.6E-48 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS07980 928bc1cde62f4e2ab4307c34d6260fe0 407 SUPERFAMILY SSF52540 194 320 4.65E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07980 928bc1cde62f4e2ab4307c34d6260fe0 407 SUPERFAMILY SSF52540 24 90 4.65E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07980 928bc1cde62f4e2ab4307c34d6260fe0 407 Gene3D G3DSA:3.40.1140.10 22 100 9.0E-9 T 06-07-2017 SMD11_RS07980 928bc1cde62f4e2ab4307c34d6260fe0 407 Gene3D G3DSA:3.40.1140.10 295 364 9.0E-9 T 06-07-2017 SMD11_RS03935 4637cb8c181774d95de2829e3a8c31c5 426 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 12 412 30.776 T 06-07-2017 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMD11_RS03935 4637cb8c181774d95de2829e3a8c31c5 426 TIGRFAM TIGR03444 EgtA_Cys_ligase: ergothioneine biosynthesis glutamate--cysteine ligase EgtA 24 414 1.2E-126 T 06-07-2017 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMD11_RS03935 4637cb8c181774d95de2829e3a8c31c5 426 SUPERFAMILY SSF55931 290 417 1.86E-35 T 06-07-2017 SMD11_RS03935 4637cb8c181774d95de2829e3a8c31c5 426 SUPERFAMILY SSF55931 29 254 1.86E-35 T 06-07-2017 SMD11_RS03935 4637cb8c181774d95de2829e3a8c31c5 426 PIRSF PIRSF017901 4 426 3.7E-104 T 06-07-2017 SMD11_RS03935 4637cb8c181774d95de2829e3a8c31c5 426 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 37 340 1.4E-68 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SMD11_RS28915 77c8a2b17e1d50e1ae2d1ec5916cd6f3 532 Pfam PF00732 GMC oxidoreductase 126 323 2.5E-5 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS28915 77c8a2b17e1d50e1ae2d1ec5916cd6f3 532 Gene3D G3DSA:3.30.410.10 180 237 1.2E-81 T 06-07-2017 SMD11_RS28915 77c8a2b17e1d50e1ae2d1ec5916cd6f3 532 Gene3D G3DSA:3.30.410.10 346 463 1.2E-81 T 06-07-2017 SMD11_RS28915 77c8a2b17e1d50e1ae2d1ec5916cd6f3 532 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 132 155 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS28915 77c8a2b17e1d50e1ae2d1ec5916cd6f3 532 Gene3D G3DSA:3.50.50.60 464 526 1.7E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS28915 77c8a2b17e1d50e1ae2d1ec5916cd6f3 532 Gene3D G3DSA:3.50.50.60 239 345 1.7E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS28915 77c8a2b17e1d50e1ae2d1ec5916cd6f3 532 Gene3D G3DSA:3.50.50.60 35 176 1.7E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS28915 77c8a2b17e1d50e1ae2d1ec5916cd6f3 532 SUPERFAMILY SSF54373 342 473 2.94E-61 T 06-07-2017 SMD11_RS28915 77c8a2b17e1d50e1ae2d1ec5916cd6f3 532 SUPERFAMILY SSF51905 470 527 1.38E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS28915 77c8a2b17e1d50e1ae2d1ec5916cd6f3 532 SUPERFAMILY SSF51905 36 349 1.38E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS28915 77c8a2b17e1d50e1ae2d1ec5916cd6f3 532 Pfam PF05199 GMC oxidoreductase 421 519 9.6E-14 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS08910 517c3d087925457ec5963d6011737d26 259 Pfam PF00005 ABC transporter 34 182 2.4E-37 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS08910 517c3d087925457ec5963d6011737d26 259 SMART SM00382 43 230 2.6E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS08910 517c3d087925457ec5963d6011737d26 259 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS08910 517c3d087925457ec5963d6011737d26 259 SUPERFAMILY SSF52540 19 252 3.71E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08910 517c3d087925457ec5963d6011737d26 259 PIRSF PIRSF039085 15 258 3.4E-112 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMD11_RS08910 517c3d087925457ec5963d6011737d26 259 Gene3D G3DSA:3.40.50.300 18 254 3.6E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05835 2dea285a284290eadcdc2f874e28f2f5 280 SUPERFAMILY SSF51430 3 271 5.11E-92 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS05835 2dea285a284290eadcdc2f874e28f2f5 280 PRINTS PR00069 Aldo-keto reductase signature 200 224 4.4E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD11_RS05835 2dea285a284290eadcdc2f874e28f2f5 280 PRINTS PR00069 Aldo-keto reductase signature 37 61 4.4E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD11_RS05835 2dea285a284290eadcdc2f874e28f2f5 280 PRINTS PR00069 Aldo-keto reductase signature 128 145 4.4E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD11_RS05835 2dea285a284290eadcdc2f874e28f2f5 280 PRINTS PR00069 Aldo-keto reductase signature 96 114 4.4E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD11_RS05835 2dea285a284290eadcdc2f874e28f2f5 280 PRINTS PR00069 Aldo-keto reductase signature 162 191 4.4E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD11_RS05835 2dea285a284290eadcdc2f874e28f2f5 280 Pfam PF00248 Aldo/keto reductase family 18 263 6.0E-47 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS05835 2dea285a284290eadcdc2f874e28f2f5 280 PIRSF PIRSF000097 2 276 3.3E-81 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SMD11_RS05835 2dea285a284290eadcdc2f874e28f2f5 280 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 128 145 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SMD11_RS05835 2dea285a284290eadcdc2f874e28f2f5 280 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 233 248 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SMD11_RS05835 2dea285a284290eadcdc2f874e28f2f5 280 Gene3D G3DSA:3.20.20.100 4 276 7.8E-101 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS08375 2681a20c8aa4737e0f1dd549e53999f8 190 Gene3D G3DSA:3.40.50.360 3 189 2.2E-54 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS08375 2681a20c8aa4737e0f1dd549e53999f8 190 SUPERFAMILY SSF52218 5 189 6.16E-41 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS08375 2681a20c8aa4737e0f1dd549e53999f8 190 Pfam PF03358 NADPH-dependent FMN reductase 44 124 1.0E-11 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMD11_RS05905 317c9faabf7f0d6faf80916a700f2d42 610 SUPERFAMILY SSF53098 14 214 8.8E-10 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS05905 317c9faabf7f0d6faf80916a700f2d42 610 Gene3D G3DSA:1.10.150.20 397 493 4.4E-24 T 06-07-2017 SMD11_RS05905 317c9faabf7f0d6faf80916a700f2d42 610 Pfam PF01612 3'-5' exonuclease 17 210 3.5E-12 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SMD11_RS05905 317c9faabf7f0d6faf80916a700f2d42 610 SMART SM00482 370 553 3.2E-53 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS05905 317c9faabf7f0d6faf80916a700f2d42 610 Gene3D G3DSA:3.30.70.370 494 585 1.5E-21 T 06-07-2017 SMD11_RS05905 317c9faabf7f0d6faf80916a700f2d42 610 Gene3D G3DSA:3.30.70.370 340 396 1.5E-21 T 06-07-2017 SMD11_RS05905 317c9faabf7f0d6faf80916a700f2d42 610 SUPERFAMILY SSF56672 215 570 2.33E-76 T 06-07-2017 SMD11_RS05905 317c9faabf7f0d6faf80916a700f2d42 610 Pfam PF00476 DNA polymerase family A 244 586 4.9E-60 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS05905 317c9faabf7f0d6faf80916a700f2d42 610 Gene3D G3DSA:1.20.1060.10 191 329 6.9E-11 T 06-07-2017 SMD11_RS05905 317c9faabf7f0d6faf80916a700f2d42 610 PRINTS PR00868 DNA-polymerase family A (pol I) signature 488 499 1.4E-9 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS05905 317c9faabf7f0d6faf80916a700f2d42 610 PRINTS PR00868 DNA-polymerase family A (pol I) signature 466 477 1.4E-9 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS05905 317c9faabf7f0d6faf80916a700f2d42 610 PRINTS PR00868 DNA-polymerase family A (pol I) signature 384 407 1.4E-9 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 10 112 2.8E-6 T 06-07-2017 IPR000014 PAS domain SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 150 261 2.5E-10 T 06-07-2017 IPR000014 PAS domain SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 Pfam PF00072 Response regulator receiver domain 1515 1607 9.9E-5 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 Gene3D G3DSA:3.30.450.20 141 261 4.1E-23 T 06-07-2017 SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 SUPERFAMILY SSF55874 328 481 9.03E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 Gene3D G3DSA:3.40.50.2300 1511 1608 6.9E-11 T 06-07-2017 SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 Gene3D G3DSA:3.30.450.20 14 132 1.4E-11 T 06-07-2017 SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 Pfam PF00989 PAS fold 150 261 1.2E-15 T 06-07-2017 IPR013767 PAS fold GO:0006355 SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 Gene3D G3DSA:3.30.565.10 318 437 2.1E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 SUPERFAMILY SSF55785 10 107 4.71E-10 T 06-07-2017 IPR000014 PAS domain SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 SMART SM00448 1513 1627 0.0064 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 SUPERFAMILY SSF52172 1508 1608 3.84E-13 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 SUPERFAMILY SSF55785 136 261 2.62E-18 T 06-07-2017 IPR000014 PAS domain SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 SMART SM00091 146 212 3.3E-6 T 06-07-2017 IPR000014 PAS domain SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 SMART SM00091 10 76 1.3E-4 T 06-07-2017 IPR000014 PAS domain SMD11_RS16145 828d81d01de084b0c0c6aa4af7df6626 1637 Pfam PF13188 PAS domain 10 64 7.5E-4 T 06-07-2017 IPR000014 PAS domain SMD11_RS05815 6c9fabf39e2ab5ece20b0a711a29a302 101 SUPERFAMILY SSF55248 5 95 4.05E-24 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SMD11_RS05815 6c9fabf39e2ab5ece20b0a711a29a302 101 Gene3D G3DSA:3.30.1360.20 2 96 2.4E-23 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SMD11_RS05815 6c9fabf39e2ab5ece20b0a711a29a302 101 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 3 95 20.104 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SMD11_RS05815 6c9fabf39e2ab5ece20b0a711a29a302 101 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 5 94 1.9E-23 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 SMD11_RS16375 7dc7233c2e27a8740cf0371d9b0d3f78 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS16375 7dc7233c2e27a8740cf0371d9b0d3f78 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 2.3E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16375 7dc7233c2e27a8740cf0371d9b0d3f78 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.3E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16375 7dc7233c2e27a8740cf0371d9b0d3f78 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 2.3E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16375 7dc7233c2e27a8740cf0371d9b0d3f78 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 2.3E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16375 7dc7233c2e27a8740cf0371d9b0d3f78 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 2.3E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16375 7dc7233c2e27a8740cf0371d9b0d3f78 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 2.3E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16375 7dc7233c2e27a8740cf0371d9b0d3f78 234 Gene3D G3DSA:3.40.50.720 3 230 2.2E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS16375 7dc7233c2e27a8740cf0371d9b0d3f78 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 5.7E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16375 7dc7233c2e27a8740cf0371d9b0d3f78 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 5.7E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16375 7dc7233c2e27a8740cf0371d9b0d3f78 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 5.7E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16375 7dc7233c2e27a8740cf0371d9b0d3f78 234 SUPERFAMILY SSF51735 3 230 1.88E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS16375 7dc7233c2e27a8740cf0371d9b0d3f78 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 176 1.6E-6 T 06-07-2017 SMD11_RS16375 7dc7233c2e27a8740cf0371d9b0d3f78 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 230 3.1E-55 T 06-07-2017 SMD11_RS25790 277a5d30613172c5bdb96cf50c5427f6 587 SUPERFAMILY SSF48208 181 580 1.32E-108 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD11_RS25790 277a5d30613172c5bdb96cf50c5427f6 587 Gene3D G3DSA:1.50.10.10 203 581 3.2E-84 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 SMD11_RS25790 277a5d30613172c5bdb96cf50c5427f6 587 Pfam PF00723 Glycosyl hydrolases family 15 528 576 3.9E-5 T 06-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 SMD11_RS25790 277a5d30613172c5bdb96cf50c5427f6 587 Pfam PF00723 Glycosyl hydrolases family 15 207 522 8.5E-68 T 06-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 SMD11_RS34185 5e410852bff9d288e61b3392bdfb3b0d 168 Gene3D G3DSA:1.10.10.10 4 110 2.6E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS34185 5e410852bff9d288e61b3392bdfb3b0d 168 Pfam PF01638 HxlR-like helix-turn-helix 21 108 1.8E-13 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type SMD11_RS34185 5e410852bff9d288e61b3392bdfb3b0d 168 SUPERFAMILY SSF46785 6 147 4.09E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23410 be77eb6227411ac74ea09d9695d505ce 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 93 189 3.3E-17 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD11_RS23410 be77eb6227411ac74ea09d9695d505ce 222 ProSitePatterns PS01228 Hypothetical cof family signature 1. 15 26 - T 06-07-2017 IPR000150 Cof protein GO:0016787 SMD11_RS23410 be77eb6227411ac74ea09d9695d505ce 222 Gene3D G3DSA:1.10.150.240 30 71 2.5E-6 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 SMD11_RS23410 be77eb6227411ac74ea09d9695d505ce 222 SUPERFAMILY SSF56784 14 208 1.65E-41 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS23410 be77eb6227411ac74ea09d9695d505ce 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 17 189 5.3E-20 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS23410 be77eb6227411ac74ea09d9695d505ce 222 Gene3D G3DSA:3.40.50.1000 79 212 1.3E-39 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS32070 ac32a3eb7a600b37923eb73238b2c3e6 320 Gene3D G3DSA:1.10.10.10 177 224 1.6E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32070 ac32a3eb7a600b37923eb73238b2c3e6 320 SMART SM00344 178 283 2.7E-7 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD11_RS32070 ac32a3eb7a600b37923eb73238b2c3e6 320 Gene3D G3DSA:1.10.10.10 5 50 1.9E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32070 ac32a3eb7a600b37923eb73238b2c3e6 320 SUPERFAMILY SSF46785 175 240 3.36E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32070 ac32a3eb7a600b37923eb73238b2c3e6 320 Pfam PF01037 Lrp/AsnC ligand binding domain 246 314 1.4E-10 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS32070 ac32a3eb7a600b37923eb73238b2c3e6 320 Pfam PF13404 AsnC-type helix-turn-helix domain 178 219 2.8E-9 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS32070 ac32a3eb7a600b37923eb73238b2c3e6 320 Pfam PF13404 AsnC-type helix-turn-helix domain 6 46 1.3E-8 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS32070 ac32a3eb7a600b37923eb73238b2c3e6 320 SUPERFAMILY SSF46785 6 51 6.96E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32070 ac32a3eb7a600b37923eb73238b2c3e6 320 Gene3D G3DSA:3.30.70.920 242 316 1.2E-12 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS32070 ac32a3eb7a600b37923eb73238b2c3e6 320 Gene3D G3DSA:3.30.70.920 70 139 8.1E-5 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS32070 ac32a3eb7a600b37923eb73238b2c3e6 320 SUPERFAMILY SSF54909 237 317 4.96E-9 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS32070 ac32a3eb7a600b37923eb73238b2c3e6 320 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 194 205 1.2E-8 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS32070 ac32a3eb7a600b37923eb73238b2c3e6 320 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 178 194 1.2E-8 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS32070 ac32a3eb7a600b37923eb73238b2c3e6 320 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 205 224 1.2E-8 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS03810 c7a8f318e6b414857e4a8294c4969dee 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 3.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03810 c7a8f318e6b414857e4a8294c4969dee 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 3.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03810 c7a8f318e6b414857e4a8294c4969dee 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 3.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03810 c7a8f318e6b414857e4a8294c4969dee 301 Gene3D G3DSA:3.40.50.720 5 264 6.4E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03810 c7a8f318e6b414857e4a8294c4969dee 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 2.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03810 c7a8f318e6b414857e4a8294c4969dee 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 2.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03810 c7a8f318e6b414857e4a8294c4969dee 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 2.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03810 c7a8f318e6b414857e4a8294c4969dee 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 2.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03810 c7a8f318e6b414857e4a8294c4969dee 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03810 c7a8f318e6b414857e4a8294c4969dee 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 2.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03810 c7a8f318e6b414857e4a8294c4969dee 301 SUPERFAMILY SSF51735 6 259 2.05E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03810 c7a8f318e6b414857e4a8294c4969dee 301 Pfam PF00106 short chain dehydrogenase 9 209 2.4E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03810 c7a8f318e6b414857e4a8294c4969dee 301 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS03320 eff8d35f31de762cfb3fb2868431ca1a 299 SMART SM00849 17 197 5.7E-30 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS03320 eff8d35f31de762cfb3fb2868431ca1a 299 SUPERFAMILY SSF56281 1 238 1.18E-58 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS03320 eff8d35f31de762cfb3fb2868431ca1a 299 Gene3D G3DSA:3.60.15.10 1 217 1.8E-54 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS03320 eff8d35f31de762cfb3fb2868431ca1a 299 Pfam PF00753 Metallo-beta-lactamase superfamily 14 197 5.3E-23 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS25210 d12b801e20b6f761ff33b5b7da1af835 473 SUPERFAMILY SSF101960 39 470 2.88E-138 T 06-07-2017 SMD11_RS25210 d12b801e20b6f761ff33b5b7da1af835 473 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 17 464 1.2E-217 T 06-07-2017 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 SMD11_RS25210 d12b801e20b6f761ff33b5b7da1af835 473 Pfam PF01458 Uncharacterized protein family (UPF0051) 219 444 1.0E-73 T 06-07-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 SMD11_RS24915 5b8024f5b3ccdaff44c7f4f17375b1a4 239 SUPERFAMILY SSF52540 4 237 1.04E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24915 5b8024f5b3ccdaff44c7f4f17375b1a4 239 Pfam PF00005 ABC transporter 22 166 6.6E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS24915 5b8024f5b3ccdaff44c7f4f17375b1a4 239 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS24915 5b8024f5b3ccdaff44c7f4f17375b1a4 239 Gene3D G3DSA:3.40.50.300 3 233 3.9E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24915 5b8024f5b3ccdaff44c7f4f17375b1a4 239 SMART SM00382 30 223 8.5E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS24915 5b8024f5b3ccdaff44c7f4f17375b1a4 239 PIRSF PIRSF039137 1 239 4.7E-110 T 06-07-2017 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 SMD11_RS11400 623abbd8c916b33b49e360d1a5b253b9 215 SUPERFAMILY SSF53474 8 208 8.96E-17 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS11400 623abbd8c916b33b49e360d1a5b253b9 215 Gene3D G3DSA:3.40.50.1820 24 207 2.0E-15 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01820 06ec509a479a377e9814b19967b6cd74 261 Gene3D G3DSA:1.10.10.10 177 228 2.8E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12055 5a159087c2e3a058caf9078c01c587a1 648 Pfam PF00890 FAD binding domain 10 430 6.7E-96 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS12055 5a159087c2e3a058caf9078c01c587a1 648 PIRSF PIRSF000171 1 607 2.3E-38 T 06-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS12055 5a159087c2e3a058caf9078c01c587a1 648 Gene3D G3DSA:3.50.50.60 4 249 5.7E-106 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12055 5a159087c2e3a058caf9078c01c587a1 648 Gene3D G3DSA:3.50.50.60 385 451 5.7E-106 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12055 5a159087c2e3a058caf9078c01c587a1 648 Gene3D G3DSA:1.20.58.100 492 584 1.9E-30 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS12055 5a159087c2e3a058caf9078c01c587a1 648 SUPERFAMILY SSF46977 493 599 3.4E-36 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS12055 5a159087c2e3a058caf9078c01c587a1 648 SUPERFAMILY SSF51905 393 452 9.32E-71 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12055 5a159087c2e3a058caf9078c01c587a1 648 SUPERFAMILY SSF51905 6 270 9.32E-71 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12055 5a159087c2e3a058caf9078c01c587a1 648 Gene3D G3DSA:3.90.700.10 250 383 4.4E-36 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS12055 5a159087c2e3a058caf9078c01c587a1 648 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 394 416 3.2E-8 T 06-07-2017 SMD11_RS12055 5a159087c2e3a058caf9078c01c587a1 648 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.2E-8 T 06-07-2017 SMD11_RS12055 5a159087c2e3a058caf9078c01c587a1 648 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 3.3E-7 T 06-07-2017 SMD11_RS12055 5a159087c2e3a058caf9078c01c587a1 648 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 509 524 3.3E-7 T 06-07-2017 SMD11_RS12055 5a159087c2e3a058caf9078c01c587a1 648 SUPERFAMILY SSF56425 243 389 8.52E-34 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS12055 5a159087c2e3a058caf9078c01c587a1 648 Pfam PF02910 Fumarate reductase flavoprotein C-term 499 596 2.0E-21 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS31635 3916b8325dd82976eb942c061edd71cc 482 Pfam PF07690 Major Facilitator Superfamily 39 429 3.2E-45 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS31635 3916b8325dd82976eb942c061edd71cc 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 129 149 4.2E-5 T 06-07-2017 SMD11_RS31635 3916b8325dd82976eb942c061edd71cc 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 225 243 4.2E-5 T 06-07-2017 SMD11_RS31635 3916b8325dd82976eb942c061edd71cc 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 159 183 4.2E-5 T 06-07-2017 SMD11_RS31635 3916b8325dd82976eb942c061edd71cc 482 Gene3D G3DSA:1.20.1250.20 35 215 3.7E-27 T 06-07-2017 SMD11_RS31635 3916b8325dd82976eb942c061edd71cc 482 Gene3D G3DSA:1.20.1250.20 283 466 3.7E-17 T 06-07-2017 SMD11_RS31635 3916b8325dd82976eb942c061edd71cc 482 SUPERFAMILY SSF103473 3 216 3.01E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS31635 3916b8325dd82976eb942c061edd71cc 482 SUPERFAMILY SSF103473 270 471 3.01E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS24770 1004215dfb2456dbbc90fbcaf0864243 259 SUPERFAMILY SSF52833 77 251 7.01E-26 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS24770 1004215dfb2456dbbc90fbcaf0864243 259 Gene3D G3DSA:3.40.30.10 77 254 3.0E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS24770 1004215dfb2456dbbc90fbcaf0864243 259 Pfam PF13462 Thioredoxin 80 253 3.9E-26 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS04655 65f6c9e9c0cdc7ab53385f97a7bd6e50 292 PIRSF PIRSF002854 6 272 4.5E-84 T 06-07-2017 IPR004872 Lipoprotein NlpA family SMD11_RS04655 65f6c9e9c0cdc7ab53385f97a7bd6e50 292 Pfam PF03180 NLPA lipoprotein 38 268 7.8E-76 T 06-07-2017 IPR004872 Lipoprotein NlpA family SMD11_RS04655 65f6c9e9c0cdc7ab53385f97a7bd6e50 292 SUPERFAMILY SSF53850 44 275 4.34E-72 T 06-07-2017 SMD11_RS04655 65f6c9e9c0cdc7ab53385f97a7bd6e50 292 Gene3D G3DSA:3.40.190.10 35 162 5.1E-48 T 06-07-2017 SMD11_RS23515 d3da38433d30ec9355d64aa9bb94e28b 575 Pfam PF00664 ABC transporter transmembrane region 38 294 6.8E-17 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS23515 d3da38433d30ec9355d64aa9bb94e28b 575 Gene3D G3DSA:1.20.1560.10 22 328 3.8E-37 T 06-07-2017 SMD11_RS23515 d3da38433d30ec9355d64aa9bb94e28b 575 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS23515 d3da38433d30ec9355d64aa9bb94e28b 575 Pfam PF00005 ABC transporter 360 507 1.4E-16 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS23515 d3da38433d30ec9355d64aa9bb94e28b 575 SUPERFAMILY SSF90123 19 328 5.76E-41 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS23515 d3da38433d30ec9355d64aa9bb94e28b 575 Gene3D G3DSA:3.40.50.300 344 567 1.7E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23515 d3da38433d30ec9355d64aa9bb94e28b 575 SUPERFAMILY SSF52540 342 567 4.38E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23515 d3da38433d30ec9355d64aa9bb94e28b 575 SMART SM00382 369 552 3.9E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS18135 faee3d002c6cebd1d1493c6d42dc5632 447 Gene3D G3DSA:3.50.50.60 3 117 7.8E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18135 faee3d002c6cebd1d1493c6d42dc5632 447 SUPERFAMILY SSF51905 168 350 8.02E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18135 faee3d002c6cebd1d1493c6d42dc5632 447 SUPERFAMILY SSF51905 4 227 5.94E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18135 faee3d002c6cebd1d1493c6d42dc5632 447 Gene3D G3DSA:3.50.50.60 118 345 1.8E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18135 faee3d002c6cebd1d1493c6d42dc5632 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.8E-10 T 06-07-2017 SMD11_RS18135 faee3d002c6cebd1d1493c6d42dc5632 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 3.8E-10 T 06-07-2017 SMD11_RS18135 faee3d002c6cebd1d1493c6d42dc5632 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 3.8E-10 T 06-07-2017 SMD11_RS18135 faee3d002c6cebd1d1493c6d42dc5632 447 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 337 3.2E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS10610 d0785fadc449bc5a1d64c100b702183e 186 Gene3D G3DSA:1.10.10.10 27 159 2.9E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS10610 d0785fadc449bc5a1d64c100b702183e 186 SUPERFAMILY SSF46785 25 159 4.02E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS10610 d0785fadc449bc5a1d64c100b702183e 186 ProSitePatterns PS01117 MarR-type HTH domain signature. 89 123 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site SMD11_RS10610 d0785fadc449bc5a1d64c100b702183e 186 SMART SM00347 48 148 6.7E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS10610 d0785fadc449bc5a1d64c100b702183e 186 Pfam PF12802 MarR family 54 114 5.7E-11 T 06-07-2017 SMD11_RS01995 f8891706e95104b00156592318578a47 194 Pfam PF04264 YceI-like domain 7 181 2.0E-43 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS01995 f8891706e95104b00156592318578a47 194 SUPERFAMILY SSF101874 5 182 1.12E-48 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS01995 f8891706e95104b00156592318578a47 194 Gene3D G3DSA:2.40.128.110 5 182 1.4E-57 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS01995 f8891706e95104b00156592318578a47 194 SMART SM00867 5 182 8.5E-62 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS05085 5bab8e4783cc987603965941cb70f746 445 SUPERFAMILY SSF56762 9 436 1.96E-89 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS05085 5bab8e4783cc987603965941cb70f746 445 Gene3D G3DSA:1.10.645.10 6 436 1.8E-85 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS05085 5bab8e4783cc987603965941cb70f746 445 Pfam PF00374 Nickel-dependent hydrogenase 248 436 3.5E-8 T 06-07-2017 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 SMD11_RS05085 5bab8e4783cc987603965941cb70f746 445 Pfam PF00374 Nickel-dependent hydrogenase 44 132 1.5E-14 T 06-07-2017 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 SMD11_RS28620 a4665cf9e8ca8299fa67d2d3dba1b9fe 1026 Pfam PF13558 Putative exonuclease SbcCD, C subunit 916 980 2.1E-13 T 06-07-2017 SMD11_RS28620 a4665cf9e8ca8299fa67d2d3dba1b9fe 1026 Pfam PF13476 AAA domain 5 204 6.0E-23 T 06-07-2017 SMD11_RS28620 a4665cf9e8ca8299fa67d2d3dba1b9fe 1026 SUPERFAMILY SSF52540 2 224 3.92E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28620 a4665cf9e8ca8299fa67d2d3dba1b9fe 1026 SUPERFAMILY SSF52540 799 1013 3.92E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28620 a4665cf9e8ca8299fa67d2d3dba1b9fe 1026 Gene3D G3DSA:3.40.50.300 2 180 4.9E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28620 a4665cf9e8ca8299fa67d2d3dba1b9fe 1026 Gene3D G3DSA:3.40.50.300 622 623 4.9E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28620 a4665cf9e8ca8299fa67d2d3dba1b9fe 1026 Gene3D G3DSA:3.40.50.300 880 1017 4.9E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22360 2cb6cfe65d762595db896f8dfa599254 454 Gene3D G3DSA:3.90.550.10 49 306 6.8E-14 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS22360 2cb6cfe65d762595db896f8dfa599254 454 SUPERFAMILY SSF53448 48 316 1.41E-27 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS22360 2cb6cfe65d762595db896f8dfa599254 454 Pfam PF13641 Glycosyltransferase like family 2 47 298 1.1E-20 T 06-07-2017 SMD11_RS29835 0af1fbc21e6b68398587d15f1e12de44 165 SMART SM00823 Phosphopantetheine attachment site 76 148 4.7E-9 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS29835 0af1fbc21e6b68398587d15f1e12de44 165 Pfam PF00550 Phosphopantetheine attachment site 78 144 1.9E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29835 0af1fbc21e6b68398587d15f1e12de44 165 SUPERFAMILY SSF47336 70 163 5.37E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29835 0af1fbc21e6b68398587d15f1e12de44 165 Gene3D G3DSA:1.10.1200.10 76 149 2.1E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29675 a5b3aff99b8db619e9308615967b424c 375 SUPERFAMILY SSF51556 55 370 2.45E-9 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS29675 a5b3aff99b8db619e9308615967b424c 375 Pfam PF04909 Amidohydrolase 193 370 2.1E-10 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 SMD11_RS29675 a5b3aff99b8db619e9308615967b424c 375 Gene3D G3DSA:3.20.20.140 9 371 2.2E-117 T 06-07-2017 SMD11_RS20035 35e6fcc36a3db0c2b6ab08c195218f6f 263 Gene3D G3DSA:3.40.50.720 5 251 2.1E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20035 35e6fcc36a3db0c2b6ab08c195218f6f 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 249 3.3E-64 T 06-07-2017 SMD11_RS20035 35e6fcc36a3db0c2b6ab08c195218f6f 263 SUPERFAMILY SSF51735 11 251 1.49E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20035 35e6fcc36a3db0c2b6ab08c195218f6f 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 7.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20035 35e6fcc36a3db0c2b6ab08c195218f6f 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 7.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20035 35e6fcc36a3db0c2b6ab08c195218f6f 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 7.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20035 35e6fcc36a3db0c2b6ab08c195218f6f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 7.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20035 35e6fcc36a3db0c2b6ab08c195218f6f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 7.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20035 35e6fcc36a3db0c2b6ab08c195218f6f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 7.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20035 35e6fcc36a3db0c2b6ab08c195218f6f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 7.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20035 35e6fcc36a3db0c2b6ab08c195218f6f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 7.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20035 35e6fcc36a3db0c2b6ab08c195218f6f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 7.5E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS33060 3247e1f6915330cb51816e99c22256d8 291 SUPERFAMILY SSF53474 18 284 9.41E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS33060 3247e1f6915330cb51816e99c22256d8 291 Gene3D G3DSA:3.40.50.1820 17 284 3.5E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS33060 3247e1f6915330cb51816e99c22256d8 291 Pfam PF00561 alpha/beta hydrolase fold 34 150 7.6E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS23930 a71860d451ebe5f3d8c97e5b458349f9 200 SUPERFAMILY SSF144091 40 193 1.24E-5 T 06-07-2017 SMD11_RS23930 a71860d451ebe5f3d8c97e5b458349f9 200 Gene3D G3DSA:1.20.1540.10 37 189 4.5E-4 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 SUPERFAMILY SSF48452 1205 1378 7.21E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 Gene3D G3DSA:1.25.40.10 922 991 8.9E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 Gene3D G3DSA:1.25.40.10 1175 1380 1.3E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 Gene3D G3DSA:1.25.40.10 1456 1484 1.3E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 Pfam PF13365 Trypsin-like peptidase domain 23 178 2.0E-10 T 06-07-2017 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 SUPERFAMILY SSF81901 580 730 1.31E-7 T 06-07-2017 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 Gene3D G3DSA:2.40.10.10 8 96 3.1E-5 T 06-07-2017 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 Pfam PF13432 Tetratricopeptide repeat 1317 1374 3.7E-4 T 06-07-2017 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 Pfam PF13432 Tetratricopeptide repeat 808 865 7.5E-5 T 06-07-2017 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 Gene3D G3DSA:1.25.40.10 794 921 5.1E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 Gene3D G3DSA:1.25.40.10 597 741 3.2E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 Gene3D G3DSA:2.40.10.10 97 200 6.4E-6 T 06-07-2017 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 Pfam PF09976 Tetratricopeptide repeat-like domain 609 723 1.2E-6 T 06-07-2017 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 Pfam PF09976 Tetratricopeptide repeat-like domain 909 1008 2.6E-8 T 06-07-2017 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 SUPERFAMILY SSF81901 801 1010 1.49E-14 T 06-07-2017 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 SUPERFAMILY SSF50494 7 202 1.01E-19 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 Gene3D G3DSA:1.25.40.10 1046 1079 4.9E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 Gene3D G3DSA:1.25.40.10 1154 1174 4.9E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS31475 66787b98f6b6a8c0708f7caabec8728c 1529 Gene3D G3DSA:1.25.40.10 992 1008 4.9E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 Gene3D G3DSA:3.30.200.20 18 97 1.1E-13 T 06-07-2017 SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 Pfam PF13360 PQQ-like domain 400 605 1.9E-17 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 Gene3D G3DSA:2.140.10.10 413 737 3.4E-26 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 Pfam PF13570 PQQ-like domain 656 691 5.0E-4 T 06-07-2017 IPR025666 Pyrrolo-quinoline quinone-like domain SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 SUPERFAMILY SSF50998 409 741 3.14E-23 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 Pfam PF00069 Protein kinase domain 22 269 4.8E-38 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 28 50 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 SMART SM00564 490 521 13.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 SMART SM00564 623 661 490.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 SMART SM00564 449 482 19.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 SMART SM00564 530 569 470.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 SMART SM00564 669 701 54.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 Gene3D G3DSA:1.10.510.10 105 307 9.3E-44 T 06-07-2017 SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 SUPERFAMILY SSF56112 19 326 1.11E-63 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 140 152 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS14690 546f02288ed00e9451712dec10f27cb4 746 SMART SM00220 22 274 3.9E-43 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS18435 55d83f8c05cdad24a4fcf51f701d7397 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 8.1E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS18435 55d83f8c05cdad24a4fcf51f701d7397 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 8.1E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS18435 55d83f8c05cdad24a4fcf51f701d7397 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 8.1E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS18435 55d83f8c05cdad24a4fcf51f701d7397 151 Gene3D G3DSA:3.30.70.920 54 144 7.5E-24 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS18435 55d83f8c05cdad24a4fcf51f701d7397 151 SUPERFAMILY SSF46785 1 60 1.33E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS18435 55d83f8c05cdad24a4fcf51f701d7397 151 Pfam PF01037 Lrp/AsnC ligand binding domain 67 138 7.8E-19 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS18435 55d83f8c05cdad24a4fcf51f701d7397 151 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 9.3E-17 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS18435 55d83f8c05cdad24a4fcf51f701d7397 151 SUPERFAMILY SSF54909 61 143 1.34E-18 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS18435 55d83f8c05cdad24a4fcf51f701d7397 151 Gene3D G3DSA:1.10.10.10 1 52 2.9E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS18435 55d83f8c05cdad24a4fcf51f701d7397 151 SMART SM00344 1 108 4.8E-39 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD11_RS18435 55d83f8c05cdad24a4fcf51f701d7397 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMD11_RS16885 4b1980733de81c5da019844d26491675 364 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 35 252 3.7E-61 T 06-07-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal SMD11_RS16885 4b1980733de81c5da019844d26491675 364 Pfam PF02096 60Kd inner membrane protein 35 252 1.1E-57 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SMD11_RS11525 6fe3a2a81f6db9669b730847702ea481 173 Pfam PF00293 NUDIX domain 43 154 3.1E-11 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS11525 6fe3a2a81f6db9669b730847702ea481 173 SUPERFAMILY SSF55811 40 171 2.98E-19 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS11525 6fe3a2a81f6db9669b730847702ea481 173 Gene3D G3DSA:3.90.79.10 43 169 2.8E-18 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS26810 b7d5ae2be0ab5a17f6c7e0af0a84e497 313 Gene3D G3DSA:3.40.1160.10 34 300 1.6E-98 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS26810 b7d5ae2be0ab5a17f6c7e0af0a84e497 313 PRINTS PR00474 Glutamate 5-kinase family signature 67 81 9.5E-9 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 SMD11_RS26810 b7d5ae2be0ab5a17f6c7e0af0a84e497 313 PRINTS PR00474 Glutamate 5-kinase family signature 251 271 9.5E-9 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 SMD11_RS26810 b7d5ae2be0ab5a17f6c7e0af0a84e497 313 PRINTS PR00474 Glutamate 5-kinase family signature 200 227 9.5E-9 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 SMD11_RS26810 b7d5ae2be0ab5a17f6c7e0af0a84e497 313 Hamap MF_00082_B Acetylglutamate kinase [argB]. 34 301 34.441 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS26810 b7d5ae2be0ab5a17f6c7e0af0a84e497 313 PIRSF PIRSF000728 21 301 2.6E-97 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS26810 b7d5ae2be0ab5a17f6c7e0af0a84e497 313 SUPERFAMILY SSF53633 15 302 3.53E-86 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS26810 b7d5ae2be0ab5a17f6c7e0af0a84e497 313 Pfam PF00696 Amino acid kinase family 36 278 6.4E-50 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS26810 b7d5ae2be0ab5a17f6c7e0af0a84e497 313 TIGRFAM TIGR00761 argB: acetylglutamate kinase 37 275 2.9E-72 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS06835 02387995cf5fd14029d6d26a45edcdac 372 Gene3D G3DSA:3.30.420.40 36 170 5.3E-44 T 06-07-2017 SMD11_RS06835 02387995cf5fd14029d6d26a45edcdac 372 Pfam PF00480 ROK family 36 346 9.1E-79 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS06835 02387995cf5fd14029d6d26a45edcdac 372 Gene3D G3DSA:3.30.420.40 171 319 5.7E-51 T 06-07-2017 SMD11_RS06835 02387995cf5fd14029d6d26a45edcdac 372 ProSitePatterns PS01125 ROK family signature. 165 192 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS06835 02387995cf5fd14029d6d26a45edcdac 372 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 37 346 9.8E-91 T 06-07-2017 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 SMD11_RS06835 02387995cf5fd14029d6d26a45edcdac 372 SUPERFAMILY SSF53067 36 347 5.14E-69 T 06-07-2017 SMD11_RS29005 6e41ba2988024af650ad7d9613efbf06 472 Gene3D G3DSA:3.30.70.360 248 352 9.0E-29 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS29005 6e41ba2988024af650ad7d9613efbf06 472 Gene3D G3DSA:3.40.630.10 363 470 3.6E-72 T 06-07-2017 SMD11_RS29005 6e41ba2988024af650ad7d9613efbf06 472 Gene3D G3DSA:3.40.630.10 71 244 3.6E-72 T 06-07-2017 SMD11_RS29005 6e41ba2988024af650ad7d9613efbf06 472 Pfam PF01546 Peptidase family M20/M25/M40 134 420 3.2E-21 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD11_RS29005 6e41ba2988024af650ad7d9613efbf06 472 SUPERFAMILY SSF55031 250 352 1.05E-23 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS29005 6e41ba2988024af650ad7d9613efbf06 472 PIRSF PIRSF005962 64 471 7.0E-80 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 SMD11_RS29005 6e41ba2988024af650ad7d9613efbf06 472 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 83 420 2.0E-69 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 SMD11_RS29005 6e41ba2988024af650ad7d9613efbf06 472 SUPERFAMILY SSF53187 70 263 2.28E-64 T 06-07-2017 SMD11_RS29005 6e41ba2988024af650ad7d9613efbf06 472 SUPERFAMILY SSF53187 366 466 2.28E-64 T 06-07-2017 SMD11_RS29005 6e41ba2988024af650ad7d9613efbf06 472 Pfam PF07687 Peptidase dimerisation domain 248 347 3.4E-9 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS18800 81b56f3298ec6104dd0020c7a3bf6e1c 457 Pfam PF00155 Aminotransferase class I and II 89 445 3.2E-72 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS18800 81b56f3298ec6104dd0020c7a3bf6e1c 457 Gene3D G3DSA:3.40.640.10 102 331 3.9E-76 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS18800 81b56f3298ec6104dd0020c7a3bf6e1c 457 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 293 306 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SMD11_RS18800 81b56f3298ec6104dd0020c7a3bf6e1c 457 Gene3D G3DSA:3.90.1150.10 332 454 3.3E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS18800 81b56f3298ec6104dd0020c7a3bf6e1c 457 SUPERFAMILY SSF53383 61 454 8.84E-113 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS19065 3bf7d7117193da3508c7f1fd4161f27d 148 SUPERFAMILY SSF52161 5 144 7.46E-59 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SMD11_RS19065 3bf7d7117193da3508c7f1fd4161f27d 148 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 146 27.959 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SMD11_RS19065 3bf7d7117193da3508c7f1fd4161f27d 148 PIRSF PIRSF002181 2 147 1.5E-46 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SMD11_RS19065 3bf7d7117193da3508c7f1fd4161f27d 148 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 06-07-2017 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 SMD11_RS19065 3bf7d7117193da3508c7f1fd4161f27d 148 Pfam PF00572 Ribosomal protein L13 14 137 2.8E-55 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SMD11_RS19065 3bf7d7117193da3508c7f1fd4161f27d 148 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 1.2E-60 T 06-07-2017 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS19065 3bf7d7117193da3508c7f1fd4161f27d 148 Gene3D G3DSA:3.90.1180.10 3 141 5.5E-62 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SMD11_RS01885 679fa0f9c4917630cfc5decf96bf2904 86 Pfam PF00550 Phosphopantetheine attachment site 9 77 8.9E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01885 679fa0f9c4917630cfc5decf96bf2904 86 SUPERFAMILY SSF47336 8 83 1.44E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01885 679fa0f9c4917630cfc5decf96bf2904 86 Gene3D G3DSA:1.10.1200.10 9 82 1.4E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS12380 1298ae8103fd14a93abd1b4e7d90e71f 249 SUPERFAMILY SSF55781 57 244 1.24E-47 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS12380 1298ae8103fd14a93abd1b4e7d90e71f 249 Gene3D G3DSA:1.10.10.10 2 70 4.3E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12380 1298ae8103fd14a93abd1b4e7d90e71f 249 Pfam PF09339 IclR helix-turn-helix domain 4 52 1.3E-13 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS12380 1298ae8103fd14a93abd1b4e7d90e71f 249 SUPERFAMILY SSF46785 3 73 8.11E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12380 1298ae8103fd14a93abd1b4e7d90e71f 249 Gene3D G3DSA:3.30.450.40 71 245 5.6E-56 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS12380 1298ae8103fd14a93abd1b4e7d90e71f 249 Pfam PF01614 Bacterial transcriptional regulator 117 241 1.4E-28 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal SMD11_RS12380 1298ae8103fd14a93abd1b4e7d90e71f 249 SMART SM00346 2 89 5.5E-26 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS19115 ef82e8c08f878a637c5c56467f83212f 277 SUPERFAMILY SSF47413 13 73 1.1E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS19115 ef82e8c08f878a637c5c56467f83212f 277 Pfam PF13560 Helix-turn-helix domain 14 75 7.3E-17 T 06-07-2017 SMD11_RS19115 ef82e8c08f878a637c5c56467f83212f 277 SMART SM00530 18 73 3.3E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS19115 ef82e8c08f878a637c5c56467f83212f 277 Gene3D G3DSA:1.10.260.40 10 73 1.0E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS27635 65ea7b2ba38bb5b4db17c20d8ea6c2d6 268 ProSitePatterns PS00893 Nudix box signature. 159 180 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD11_RS27635 65ea7b2ba38bb5b4db17c20d8ea6c2d6 268 Gene3D G3DSA:1.10.10.10 3 71 8.4E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27635 65ea7b2ba38bb5b4db17c20d8ea6c2d6 268 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 1.1E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS27635 65ea7b2ba38bb5b4db17c20d8ea6c2d6 268 Gene3D G3DSA:3.90.79.10 87 259 1.0E-35 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS27635 65ea7b2ba38bb5b4db17c20d8ea6c2d6 268 SMART SM00345 8 67 2.7E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS27635 65ea7b2ba38bb5b4db17c20d8ea6c2d6 268 SUPERFAMILY SSF46785 3 71 1.5E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27635 65ea7b2ba38bb5b4db17c20d8ea6c2d6 268 SUPERFAMILY SSF55811 87 259 3.52E-36 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS27635 65ea7b2ba38bb5b4db17c20d8ea6c2d6 268 Pfam PF00293 NUDIX domain 125 236 1.3E-17 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS27635 65ea7b2ba38bb5b4db17c20d8ea6c2d6 268 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 3.3E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS27635 65ea7b2ba38bb5b4db17c20d8ea6c2d6 268 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 3.3E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS11370 84c6ebf0ff6ffc2018617be69e4a10ec 209 SUPERFAMILY SSF56420 32 196 3.01E-53 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS11370 84c6ebf0ff6ffc2018617be69e4a10ec 209 Hamap MF_00163 Peptide deformylase [def]. 33 199 27.902 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS11370 84c6ebf0ff6ffc2018617be69e4a10ec 209 Gene3D G3DSA:3.90.45.10 35 198 2.5E-56 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS11370 84c6ebf0ff6ffc2018617be69e4a10ec 209 PRINTS PR01576 Peptide deformylase signature 138 156 2.1E-32 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS11370 84c6ebf0ff6ffc2018617be69e4a10ec 209 PRINTS PR01576 Peptide deformylase signature 126 137 2.1E-32 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS11370 84c6ebf0ff6ffc2018617be69e4a10ec 209 PRINTS PR01576 Peptide deformylase signature 64 93 2.1E-32 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS11370 84c6ebf0ff6ffc2018617be69e4a10ec 209 PRINTS PR01576 Peptide deformylase signature 157 186 2.1E-32 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS11370 84c6ebf0ff6ffc2018617be69e4a10ec 209 PIRSF PIRSF004749 1 205 2.5E-43 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS11370 84c6ebf0ff6ffc2018617be69e4a10ec 209 Pfam PF01327 Polypeptide deformylase 35 189 1.6E-43 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS11370 84c6ebf0ff6ffc2018617be69e4a10ec 209 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 40 196 2.0E-39 T 06-07-2017 IPR023635 Peptide deformylase SMD11_RS11590 a21406dc5a24e01e946606e0f70fc928 315 SUPERFAMILY SSF55811 123 306 2.98E-49 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS11590 a21406dc5a24e01e946606e0f70fc928 315 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 42 137 2.1E-14 T 06-07-2017 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 SMD11_RS11590 a21406dc5a24e01e946606e0f70fc928 315 Gene3D G3DSA:3.90.79.10 137 305 3.4E-51 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS11590 a21406dc5a24e01e946606e0f70fc928 315 ProSitePatterns PS00893 Nudix box signature. 206 227 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD11_RS11590 a21406dc5a24e01e946606e0f70fc928 315 Pfam PF00293 NUDIX domain 174 283 1.1E-19 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS11590 a21406dc5a24e01e946606e0f70fc928 315 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 140 170 8.0E-14 T 06-07-2017 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 SMD11_RS24775 37b32e9ca7f78cca4a1e7dea56aa9223 287 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 8 261 7.3E-41 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SMD11_RS24775 37b32e9ca7f78cca4a1e7dea56aa9223 287 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 256 2.8E-63 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SMD11_RS24775 37b32e9ca7f78cca4a1e7dea56aa9223 287 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 8 262 15.63 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SMD11_RS24775 37b32e9ca7f78cca4a1e7dea56aa9223 287 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 140 152 - T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SMD11_RS18860 3d8079aa8f2b3d49d3bac7902861cf1a 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.6E-64 T 06-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 SMD11_RS18860 3d8079aa8f2b3d49d3bac7902861cf1a 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 06-07-2017 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18860 3d8079aa8f2b3d49d3bac7902861cf1a 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 5.2E-60 T 06-07-2017 IPR023798 Ribosomal protein S7 domain SMD11_RS18860 3d8079aa8f2b3d49d3bac7902861cf1a 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.744 T 06-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 SMD11_RS18860 3d8079aa8f2b3d49d3bac7902861cf1a 156 SUPERFAMILY SSF47973 1 149 4.06E-57 T 06-07-2017 IPR023798 Ribosomal protein S7 domain SMD11_RS18860 3d8079aa8f2b3d49d3bac7902861cf1a 156 PIRSF PIRSF002122 7 156 2.5E-55 T 06-07-2017 IPR000235 Ribosomal protein S5/S7 GO:0006412 SMD11_RS18860 3d8079aa8f2b3d49d3bac7902861cf1a 156 Gene3D G3DSA:1.10.455.10 8 156 4.3E-61 T 06-07-2017 IPR023798 Ribosomal protein S7 domain SMD11_RS02595 b54a6583719daa0168f9395e7506058e 597 Pfam PF06259 Alpha/beta hydrolase 357 524 4.1E-29 T 06-07-2017 IPR010427 Protein of unknown function DUF1023 SMD11_RS05005 e6c66d7aafbf25afeee7d97c32e5e03b 219 Pfam PF02254 TrkA-N domain 4 118 2.4E-21 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SMD11_RS05005 e6c66d7aafbf25afeee7d97c32e5e03b 219 Gene3D G3DSA:3.40.50.720 1 144 8.0E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05005 e6c66d7aafbf25afeee7d97c32e5e03b 219 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 3.8E-12 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS05005 e6c66d7aafbf25afeee7d97c32e5e03b 219 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 3.8E-12 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS05005 e6c66d7aafbf25afeee7d97c32e5e03b 219 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 3.8E-12 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS05005 e6c66d7aafbf25afeee7d97c32e5e03b 219 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 3.8E-12 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 SMD11_RS05005 e6c66d7aafbf25afeee7d97c32e5e03b 219 SUPERFAMILY SSF51735 1 144 7.88E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10390 a9d6adf09a3a50042b63f0b10d631fd3 577 SMART SM00642 31 433 7.8E-123 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS10390 a9d6adf09a3a50042b63f0b10d631fd3 577 SUPERFAMILY SSF51445 34 481 3.78E-135 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS10390 a9d6adf09a3a50042b63f0b10d631fd3 577 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 23 567 2.6E-299 T 06-07-2017 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 SMD11_RS10390 a9d6adf09a3a50042b63f0b10d631fd3 577 Gene3D G3DSA:3.90.400.10 123 190 9.6E-25 T 06-07-2017 SMD11_RS10390 a9d6adf09a3a50042b63f0b10d631fd3 577 Pfam PF00128 Alpha amylase, catalytic domain 46 402 3.7E-79 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS10390 a9d6adf09a3a50042b63f0b10d631fd3 577 SUPERFAMILY SSF51011 485 567 6.57E-16 T 06-07-2017 SMD11_RS10390 a9d6adf09a3a50042b63f0b10d631fd3 577 Gene3D G3DSA:3.20.20.80 460 474 2.3E-112 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS10390 a9d6adf09a3a50042b63f0b10d631fd3 577 Gene3D G3DSA:3.20.20.80 25 122 2.3E-112 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS10390 a9d6adf09a3a50042b63f0b10d631fd3 577 Gene3D G3DSA:3.20.20.80 198 427 2.3E-112 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS10390 a9d6adf09a3a50042b63f0b10d631fd3 577 Gene3D G3DSA:2.60.40.1180 486 566 1.2E-10 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta SMD11_RS10390 a9d6adf09a3a50042b63f0b10d631fd3 577 Pfam PF16657 Maltogenic Amylase, C-terminal domain 481 564 1.5E-21 T 06-07-2017 IPR032091 Maltogenic Amylase, C-terminal SMD11_RS11135 b81aa48e4d6b760449b30e86d9959a1a 375 Gene3D G3DSA:1.20.1250.20 2 182 2.1E-27 T 06-07-2017 SMD11_RS11135 b81aa48e4d6b760449b30e86d9959a1a 375 Gene3D G3DSA:1.20.1250.20 198 368 1.4E-9 T 06-07-2017 SMD11_RS11135 b81aa48e4d6b760449b30e86d9959a1a 375 Pfam PF07690 Major Facilitator Superfamily 6 338 2.2E-33 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS11135 b81aa48e4d6b760449b30e86d9959a1a 375 SUPERFAMILY SSF103473 2 368 1.44E-47 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS26075 bb92e08bd06acbc2123259bb1b0dc13b 532 Gene3D G3DSA:3.90.226.10 5 225 1.3E-48 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS26075 bb92e08bd06acbc2123259bb1b0dc13b 532 Pfam PF01039 Carboxyl transferase domain 7 444 5.5E-52 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS26075 bb92e08bd06acbc2123259bb1b0dc13b 532 SUPERFAMILY SSF52096 5 227 7.15E-56 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS26075 bb92e08bd06acbc2123259bb1b0dc13b 532 SUPERFAMILY SSF52096 254 473 1.71E-43 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS26075 bb92e08bd06acbc2123259bb1b0dc13b 532 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 75 89 1.7E-24 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 SMD11_RS26075 bb92e08bd06acbc2123259bb1b0dc13b 532 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 146 163 1.7E-24 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 SMD11_RS26075 bb92e08bd06acbc2123259bb1b0dc13b 532 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 109 127 1.7E-24 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 SMD11_RS26075 bb92e08bd06acbc2123259bb1b0dc13b 532 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 175 186 1.7E-24 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 SMD11_RS26075 bb92e08bd06acbc2123259bb1b0dc13b 532 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 197 206 1.7E-24 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 SMD11_RS26075 bb92e08bd06acbc2123259bb1b0dc13b 532 Gene3D G3DSA:3.90.226.10 260 471 3.3E-30 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS28330 ebf9ec5bcd459dc268abf0c8036d0d89 122 Gene3D G3DSA:1.10.10.10 64 95 8.5E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28330 ebf9ec5bcd459dc268abf0c8036d0d89 122 Pfam PF05331 Protein of unknown function (DUF742) 13 122 3.7E-29 T 06-07-2017 IPR007995 Protein of unknown function DUF742 SMD11_RS08130 2bd363abc42b9d3d4a0a24992228ed11 474 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 77 470 3.6E-135 T 06-07-2017 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 SMD11_RS08130 2bd363abc42b9d3d4a0a24992228ed11 474 Gene3D G3DSA:3.40.50.2000 312 453 3.4E-29 T 06-07-2017 SMD11_RS08130 2bd363abc42b9d3d4a0a24992228ed11 474 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 307 440 2.4E-11 T 06-07-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 SMD11_RS08130 2bd363abc42b9d3d4a0a24992228ed11 474 SUPERFAMILY SSF53756 71 470 7.85E-78 T 06-07-2017 SMD11_RS08130 2bd363abc42b9d3d4a0a24992228ed11 474 Gene3D G3DSA:3.40.50.2000 73 311 2.5E-16 T 06-07-2017 SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 SUPERFAMILY SSF48452 798 920 1.24E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 SUPERFAMILY SSF48452 117 289 4.14E-32 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 SMART SM01043 121 266 6.3E-43 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 SUPERFAMILY SSF52540 338 417 2.42E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 SUPERFAMILY SSF52540 466 603 2.42E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 Gene3D G3DSA:1.25.40.10 829 909 4.5E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 Gene3D G3DSA:1.25.40.10 127 242 4.5E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 Gene3D G3DSA:1.25.40.10 1006 1075 4.5E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 Gene3D G3DSA:3.40.50.300 460 504 7.1E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 Gene3D G3DSA:3.40.50.300 342 401 7.1E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 Pfam PF00486 Transcriptional regulatory protein, C terminal 42 114 1.3E-10 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 Pfam PF03704 Bacterial transcriptional activator domain 121 266 3.3E-39 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 Gene3D G3DSA:1.10.10.10 30 115 5.4E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 SUPERFAMILY SSF46894 24 114 2.21E-14 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 Pfam PF13191 AAA ATPase domain 341 506 3.1E-21 T 06-07-2017 SMD11_RS29950 4d101ea7a6ff5fb358486e4fae814678 1111 SMART SM00862 35 114 5.7E-13 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS31170 8db792072ed04e1e7151aa93db359c64 250 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 23 249 1.3E-55 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD11_RS31170 8db792072ed04e1e7151aa93db359c64 250 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 195 212 - T 06-07-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 SMD11_RS31170 8db792072ed04e1e7151aa93db359c64 250 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 21 250 31.746 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD11_RS31170 8db792072ed04e1e7151aa93db359c64 250 SUPERFAMILY SSF64005 20 244 3.66E-61 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD11_RS31170 8db792072ed04e1e7151aa93db359c64 250 Gene3D G3DSA:3.40.1180.10 20 249 1.4E-69 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD11_RS31170 8db792072ed04e1e7151aa93db359c64 250 Pfam PF01255 Putative undecaprenyl diphosphate synthase 28 249 1.8E-59 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD11_RS28515 1888766d03dc042bc488feb33a103235 425 SUPERFAMILY SSF103473 4 401 2.62E-42 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS28515 1888766d03dc042bc488feb33a103235 425 Gene3D G3DSA:1.20.1250.20 4 188 1.8E-20 T 06-07-2017 SMD11_RS28515 1888766d03dc042bc488feb33a103235 425 Pfam PF07690 Major Facilitator Superfamily 8 322 2.3E-21 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS28515 1888766d03dc042bc488feb33a103235 425 Gene3D G3DSA:1.20.1250.20 211 403 2.5E-12 T 06-07-2017 SMD11_RS01090 96dbc7bc90e4051b2e706184cf033bad 510 Gene3D G3DSA:1.20.1250.20 18 196 1.1E-21 T 06-07-2017 SMD11_RS01090 96dbc7bc90e4051b2e706184cf033bad 510 Pfam PF07690 Major Facilitator Superfamily 26 412 3.3E-44 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS01090 96dbc7bc90e4051b2e706184cf033bad 510 Gene3D G3DSA:1.20.1250.20 266 423 3.3E-16 T 06-07-2017 SMD11_RS01090 96dbc7bc90e4051b2e706184cf033bad 510 Gene3D G3DSA:1.20.1250.20 459 484 3.3E-16 T 06-07-2017 SMD11_RS01090 96dbc7bc90e4051b2e706184cf033bad 510 SUPERFAMILY SSF103473 10 204 3.14E-53 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS01090 96dbc7bc90e4051b2e706184cf033bad 510 SUPERFAMILY SSF103473 251 422 3.14E-53 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS01090 96dbc7bc90e4051b2e706184cf033bad 510 SUPERFAMILY SSF103473 458 484 3.14E-53 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS02720 ca7318258320fac0ea28998ef594115e 210 Pfam PF08445 FR47-like protein 147 199 2.3E-5 T 06-07-2017 IPR013653 FR47-like GO:0016747 SMD11_RS02720 ca7318258320fac0ea28998ef594115e 210 Gene3D G3DSA:3.40.630.30 87 202 1.1E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS02720 ca7318258320fac0ea28998ef594115e 210 SUPERFAMILY SSF55729 95 202 2.4E-13 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS21365 0412ed8dfea13f71fb89e1df5f1cdf1a 441 Pfam PF04286 Protein of unknown function (DUF445) 76 438 1.2E-98 T 06-07-2017 IPR007383 Protein of unknown function DUF445 SMD11_RS24220 2b6fdc781bcdd4fc64e982799dca44dd 269 PIRSF PIRSF000007 1 263 8.2E-129 T 06-07-2017 IPR009152 Ubiquinol-cytochrome-c reductase, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 SMD11_RS24220 2b6fdc781bcdd4fc64e982799dca44dd 269 Gene3D G3DSA:1.10.760.10 142 224 1.1E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMD11_RS24220 2b6fdc781bcdd4fc64e982799dca44dd 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 48 122 1.5E-8 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMD11_RS24220 2b6fdc781bcdd4fc64e982799dca44dd 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 142 216 1.3E-12 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMD11_RS24220 2b6fdc781bcdd4fc64e982799dca44dd 269 Gene3D G3DSA:1.10.760.10 48 134 4.7E-18 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMD11_RS24220 2b6fdc781bcdd4fc64e982799dca44dd 269 SUPERFAMILY SSF46626 124 218 8.45E-27 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMD11_RS24220 2b6fdc781bcdd4fc64e982799dca44dd 269 SUPERFAMILY SSF46626 13 128 7.86E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 SMD11_RS26930 b09c36edf217bb60459bed185197a896 275 Gene3D G3DSA:3.40.50.1820 36 265 5.9E-70 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS26930 b09c36edf217bb60459bed185197a896 275 Pfam PF01674 Lipase (class 2) 53 252 2.2E-37 T 06-07-2017 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 SMD11_RS26930 b09c36edf217bb60459bed185197a896 275 SUPERFAMILY SSF53474 48 225 1.09E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS06300 f438843224f9ddd8eea63544c787fa7d 494 SMART SM00046 199 331 6.4E-5 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMD11_RS06300 f438843224f9ddd8eea63544c787fa7d 494 Pfam PF00781 Diacylglycerol kinase catalytic domain 200 321 1.4E-13 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMD11_RS06300 f438843224f9ddd8eea63544c787fa7d 494 Pfam PF01569 PAP2 superfamily 66 175 7.3E-17 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS06300 f438843224f9ddd8eea63544c787fa7d 494 SMART SM00014 63 172 9.7E-21 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS06300 f438843224f9ddd8eea63544c787fa7d 494 SUPERFAMILY SSF111331 199 489 1.5E-44 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMD11_RS06300 f438843224f9ddd8eea63544c787fa7d 494 SUPERFAMILY SSF48317 9 183 2.49E-35 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS06300 f438843224f9ddd8eea63544c787fa7d 494 Gene3D G3DSA:1.20.144.10 10 183 6.8E-30 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS26855 611e9115bb98161e7c17689172e3e560 188 SUPERFAMILY SSF52402 16 157 4.44E-22 T 06-07-2017 SMD11_RS26855 611e9115bb98161e7c17689172e3e560 188 Gene3D G3DSA:3.40.50.620 15 155 2.7E-24 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS26855 611e9115bb98161e7c17689172e3e560 188 PRINTS PR01438 Universal stress protein signature 133 155 7.7E-6 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS26855 611e9115bb98161e7c17689172e3e560 188 PRINTS PR01438 Universal stress protein signature 14 32 7.7E-6 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS26855 611e9115bb98161e7c17689172e3e560 188 PRINTS PR01438 Universal stress protein signature 115 127 7.7E-6 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS26855 611e9115bb98161e7c17689172e3e560 188 Pfam PF00582 Universal stress protein family 16 155 1.4E-17 T 06-07-2017 IPR006016 UspA GO:0006950 SMD11_RS30220 9b4c48bffd6aaf43964e7cb74e2360cd 406 SUPERFAMILY SSF53474 261 365 1.51E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30220 9b4c48bffd6aaf43964e7cb74e2360cd 406 Gene3D G3DSA:3.40.50.1820 251 340 2.7E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30220 9b4c48bffd6aaf43964e7cb74e2360cd 406 Gene3D G3DSA:3.40.50.1820 4 47 2.7E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS31240 391d3dd053c4de146b17cbe31198417f 356 Gene3D G3DSA:1.10.3470.10 34 352 2.0E-96 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS31240 391d3dd053c4de146b17cbe31198417f 356 SUPERFAMILY SSF81345 32 350 2.48E-76 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS31240 391d3dd053c4de146b17cbe31198417f 356 Pfam PF01032 FecCD transport family 41 350 5.5E-90 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD11_RS26585 18e09c5ac1cb545dd5ce9f7beb8b094c 293 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 106 132 6.6E-37 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMD11_RS26585 18e09c5ac1cb545dd5ce9f7beb8b094c 293 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 2 29 6.6E-37 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMD11_RS26585 18e09c5ac1cb545dd5ce9f7beb8b094c 293 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 88 106 6.6E-37 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMD11_RS26585 18e09c5ac1cb545dd5ce9f7beb8b094c 293 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 156 184 6.6E-37 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMD11_RS26585 18e09c5ac1cb545dd5ce9f7beb8b094c 293 Pfam PF00902 Sec-independent protein translocase protein (TatC) 5 224 1.0E-61 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMD11_RS26585 18e09c5ac1cb545dd5ce9f7beb8b094c 293 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 1 243 16.975 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMD11_RS26585 18e09c5ac1cb545dd5ce9f7beb8b094c 293 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 3 229 5.6E-56 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 SMD11_RS17745 b1d45e905538743b6c1771da7a068369 482 Gene3D G3DSA:1.20.1250.20 8 189 2.9E-34 T 06-07-2017 SMD11_RS17745 b1d45e905538743b6c1771da7a068369 482 Gene3D G3DSA:1.20.1250.20 260 453 1.0E-13 T 06-07-2017 SMD11_RS17745 b1d45e905538743b6c1771da7a068369 482 SUPERFAMILY SSF103473 243 455 7.85E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS17745 b1d45e905538743b6c1771da7a068369 482 SUPERFAMILY SSF103473 6 192 7.85E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS17745 b1d45e905538743b6c1771da7a068369 482 Pfam PF07690 Major Facilitator Superfamily 15 405 2.3E-51 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS17745 b1d45e905538743b6c1771da7a068369 482 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 407 2.1E-78 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS17630 3fe641c124d0cb06b671434cdace8680 284 SMART SM00530 17 72 4.4E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS17630 3fe641c124d0cb06b671434cdace8680 284 Pfam PF13560 Helix-turn-helix domain 13 74 1.3E-13 T 06-07-2017 SMD11_RS17630 3fe641c124d0cb06b671434cdace8680 284 Gene3D G3DSA:1.10.260.40 5 73 2.1E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS17630 3fe641c124d0cb06b671434cdace8680 284 SUPERFAMILY SSF47413 9 68 2.82E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS03485 44e17fd1c264969fdf11e9ad5b911c92 375 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 12 253 5.9E-15 T 06-07-2017 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 SMD11_RS03485 44e17fd1c264969fdf11e9ad5b911c92 375 SUPERFAMILY SSF53067 8 123 2.42E-7 T 06-07-2017 SMD11_RS03485 44e17fd1c264969fdf11e9ad5b911c92 375 SUPERFAMILY SSF53067 126 259 1.23E-34 T 06-07-2017 SMD11_RS03485 44e17fd1c264969fdf11e9ad5b911c92 375 SUPERFAMILY SSF53067 302 356 1.23E-34 T 06-07-2017 SMD11_RS03485 44e17fd1c264969fdf11e9ad5b911c92 375 Gene3D G3DSA:3.30.420.40 8 136 9.4E-4 T 06-07-2017 SMD11_RS23885 110e84b8fb81a935b558858ef01dcfb1 545 Pfam PF00128 Alpha amylase, catalytic domain 47 391 1.1E-79 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS23885 110e84b8fb81a935b558858ef01dcfb1 545 Gene3D G3DSA:3.20.20.80 202 479 4.3E-110 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS23885 110e84b8fb81a935b558858ef01dcfb1 545 Gene3D G3DSA:3.20.20.80 23 123 4.3E-110 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS23885 110e84b8fb81a935b558858ef01dcfb1 545 SUPERFAMILY SSF51445 24 478 3.95E-129 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS23885 110e84b8fb81a935b558858ef01dcfb1 545 Pfam PF11941 Domain of unknown function (DUF3459) 464 543 6.8E-6 T 06-07-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) SMD11_RS23885 110e84b8fb81a935b558858ef01dcfb1 545 SMART SM00642 32 419 2.7E-129 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SMD11_RS23885 110e84b8fb81a935b558858ef01dcfb1 545 Gene3D G3DSA:3.90.400.10 124 201 2.2E-28 T 06-07-2017 SMD11_RS31650 09c9246781532553a1420239e7afa58e 162 Pfam PF00255 Glutathione peroxidase 3 109 1.7E-37 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SMD11_RS31650 09c9246781532553a1420239e7afa58e 162 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 06-07-2017 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 SMD11_RS31650 09c9246781532553a1420239e7afa58e 162 PIRSF PIRSF000303 1 162 6.3E-61 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SMD11_RS31650 09c9246781532553a1420239e7afa58e 162 PRINTS PR01011 Glutathione peroxidase family signature 122 131 5.1E-18 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SMD11_RS31650 09c9246781532553a1420239e7afa58e 162 PRINTS PR01011 Glutathione peroxidase family signature 56 72 5.1E-18 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SMD11_RS31650 09c9246781532553a1420239e7afa58e 162 PRINTS PR01011 Glutathione peroxidase family signature 21 38 5.1E-18 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SMD11_RS31650 09c9246781532553a1420239e7afa58e 162 SUPERFAMILY SSF52833 1 160 1.99E-55 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS31650 09c9246781532553a1420239e7afa58e 162 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 06-07-2017 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 SMD11_RS31650 09c9246781532553a1420239e7afa58e 162 Gene3D G3DSA:3.40.30.10 1 160 8.6E-60 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS19490 71bc474e72f1215935998353fb5c22cc 76 Pfam PF04149 Domain of unknown function (DUF397) 17 70 3.3E-18 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS30290 b3982a2267dc8a2995ccf91a666c4b4c 570 Pfam PF04183 IucA / IucC family 133 353 1.5E-33 T 06-07-2017 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 SMD11_RS30290 b3982a2267dc8a2995ccf91a666c4b4c 570 Pfam PF06276 Ferric iron reductase FhuF-like transporter 378 532 9.1E-11 T 06-07-2017 IPR022770 Ferric iron reductase FhuF domain SMD11_RS30480 57ee2dd5ffc1d0113501c608a94e6b5d 673 Gene3D G3DSA:3.40.50.300 394 641 3.2E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30480 57ee2dd5ffc1d0113501c608a94e6b5d 673 Pfam PF00005 ABC transporter 423 577 3.9E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS30480 57ee2dd5ffc1d0113501c608a94e6b5d 673 Gene3D G3DSA:1.20.1560.10 65 360 7.0E-9 T 06-07-2017 SMD11_RS30480 57ee2dd5ffc1d0113501c608a94e6b5d 673 SUPERFAMILY SSF90123 63 359 1.03E-14 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS30480 57ee2dd5ffc1d0113501c608a94e6b5d 673 SUPERFAMILY SSF52540 385 648 1.51E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30480 57ee2dd5ffc1d0113501c608a94e6b5d 673 SMART SM00382 432 624 2.3E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS14175 0d1879438491ab2e0b9d83da31cd8aa8 417 SUPERFAMILY SSF47384 138 221 9.22E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS14175 0d1879438491ab2e0b9d83da31cd8aa8 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 360 7.5E-21 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS14175 0d1879438491ab2e0b9d83da31cd8aa8 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 335 7.5E-21 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS14175 0d1879438491ab2e0b9d83da31cd8aa8 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 379 7.5E-21 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS14175 0d1879438491ab2e0b9d83da31cd8aa8 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 307 321 7.5E-21 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS14175 0d1879438491ab2e0b9d83da31cd8aa8 417 Pfam PF00512 His Kinase A (phospho-acceptor) domain 156 219 1.2E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS14175 0d1879438491ab2e0b9d83da31cd8aa8 417 Gene3D G3DSA:1.10.287.130 147 207 2.6E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS14175 0d1879438491ab2e0b9d83da31cd8aa8 417 SUPERFAMILY SSF55874 211 379 1.17E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14175 0d1879438491ab2e0b9d83da31cd8aa8 417 SMART SM00387 266 382 5.5E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14175 0d1879438491ab2e0b9d83da31cd8aa8 417 Gene3D G3DSA:3.30.565.10 208 380 4.6E-46 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14175 0d1879438491ab2e0b9d83da31cd8aa8 417 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 269 381 1.0E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14175 0d1879438491ab2e0b9d83da31cd8aa8 417 SMART SM00388 155 221 7.4E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS09830 9e0bd0358428d421b36016dd4dc8a5bc 322 Pfam PF13466 STAS domain 230 309 4.2E-15 T 06-07-2017 IPR002645 STAS domain SMD11_RS09830 9e0bd0358428d421b36016dd4dc8a5bc 322 SUPERFAMILY SSF52091 230 316 5.1E-12 T 06-07-2017 IPR002645 STAS domain SMD11_RS09830 9e0bd0358428d421b36016dd4dc8a5bc 322 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 45 204 1.1E-26 T 06-07-2017 IPR025847 MEDS domain SMD11_RS09830 9e0bd0358428d421b36016dd4dc8a5bc 322 Gene3D G3DSA:3.30.750.24 230 310 3.5E-11 T 06-07-2017 IPR002645 STAS domain SMD11_RS19575 ae9982df5dd42a1de0f317c9c28c38de 523 Gene3D G3DSA:3.40.50.410 62 232 4.2E-10 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS19575 ae9982df5dd42a1de0f317c9c28c38de 523 Pfam PF13768 von Willebrand factor type A domain 62 218 9.4E-10 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS19575 ae9982df5dd42a1de0f317c9c28c38de 523 SUPERFAMILY SSF53300 62 234 3.18E-20 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS19575 ae9982df5dd42a1de0f317c9c28c38de 523 SMART SM00327 58 235 9.2E-9 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS16870 4d34be5a9080242ed24bb22385fe0a41 350 SUPERFAMILY SSF52540 69 318 1.3E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16870 4d34be5a9080242ed24bb22385fe0a41 350 Pfam PF13614 AAA domain 69 245 1.0E-57 T 06-07-2017 IPR025669 AAA domain SMD11_RS16870 4d34be5a9080242ed24bb22385fe0a41 350 Gene3D G3DSA:3.40.50.300 71 319 4.6E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02105 cffce43658a1486fef1053d8b3b10b6d 505 Pfam PF00083 Sugar (and other) transporter 30 460 6.0E-49 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMD11_RS02105 cffce43658a1486fef1053d8b3b10b6d 505 Gene3D G3DSA:1.20.1250.20 271 456 9.2E-19 T 06-07-2017 SMD11_RS02105 cffce43658a1486fef1053d8b3b10b6d 505 Gene3D G3DSA:1.20.1250.20 27 238 5.7E-30 T 06-07-2017 SMD11_RS02105 cffce43658a1486fef1053d8b3b10b6d 505 ProSitePatterns PS00216 Sugar transport proteins signature 1. 327 344 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS02105 cffce43658a1486fef1053d8b3b10b6d 505 SUPERFAMILY SSF103473 25 459 2.35E-69 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS02105 cffce43658a1486fef1053d8b3b10b6d 505 ProSitePatterns PS00217 Sugar transport proteins signature 2. 139 164 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS26480 58c56e2232ee4ff37fb04f45dfceb319 412 Pfam PF02163 Peptidase family M50 166 220 3.0E-7 T 06-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 SMD11_RS26480 58c56e2232ee4ff37fb04f45dfceb319 412 SUPERFAMILY SSF54631 285 401 7.31E-11 T 06-07-2017 SMD11_RS26480 58c56e2232ee4ff37fb04f45dfceb319 412 PIRSF PIRSF006404 31 409 3.9E-105 T 06-07-2017 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS SMD11_RS26480 58c56e2232ee4ff37fb04f45dfceb319 412 Gene3D G3DSA:3.10.580.10 285 400 8.6E-10 T 06-07-2017 SMD11_RS05370 8a7897fe7812f89592bd481ff956377a 353 SUPERFAMILY SSF56796 9 347 3.93E-57 T 06-07-2017 SMD11_RS05370 8a7897fe7812f89592bd481ff956377a 353 Gene3D G3DSA:3.40.50.1970 8 157 2.9E-28 T 06-07-2017 SMD11_RS05370 8a7897fe7812f89592bd481ff956377a 353 Gene3D G3DSA:1.20.1090.10 159 348 2.8E-59 T 06-07-2017 SMD11_RS05370 8a7897fe7812f89592bd481ff956377a 353 PIRSF PIRSF000112 2 353 1.8E-98 T 06-07-2017 SMD11_RS05370 8a7897fe7812f89592bd481ff956377a 353 Pfam PF13685 Iron-containing alcohol dehydrogenase 16 270 9.3E-55 T 06-07-2017 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|KEGG: 00630+1.1.1.26|MetaCyc: PWY-6349|MetaCyc: PWY-7294|MetaCyc: PWY-7295 SMD11_RS06400 de7ffecbce658cf559e45544cbd967bb 966 SMART SM00421 895 952 1.9E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS06400 de7ffecbce658cf559e45544cbd967bb 966 SUPERFAMILY SSF52540 40 119 2.19E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS06400 de7ffecbce658cf559e45544cbd967bb 966 SUPERFAMILY SSF52540 168 283 2.19E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS06400 de7ffecbce658cf559e45544cbd967bb 966 SUPERFAMILY SSF46894 888 950 2.99E-14 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS06400 de7ffecbce658cf559e45544cbd967bb 966 Pfam PF13191 AAA ATPase domain 41 201 4.4E-13 T 06-07-2017 SMD11_RS06400 de7ffecbce658cf559e45544cbd967bb 966 ProSitePatterns PS00622 LuxR-type HTH domain signature. 912 939 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS06400 de7ffecbce658cf559e45544cbd967bb 966 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 928 940 2.2E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS06400 de7ffecbce658cf559e45544cbd967bb 966 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 912 928 2.2E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS06400 de7ffecbce658cf559e45544cbd967bb 966 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 898 912 2.2E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS06400 de7ffecbce658cf559e45544cbd967bb 966 Gene3D G3DSA:1.10.10.10 888 948 1.2E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06400 de7ffecbce658cf559e45544cbd967bb 966 Pfam PF00196 Bacterial regulatory proteins, luxR family 897 948 4.8E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS06400 de7ffecbce658cf559e45544cbd967bb 966 Gene3D G3DSA:3.40.50.300 164 209 2.6E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS06400 de7ffecbce658cf559e45544cbd967bb 966 Gene3D G3DSA:3.40.50.300 44 107 2.6E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS06400 de7ffecbce658cf559e45544cbd967bb 966 Gene3D G3DSA:1.25.40.10 817 866 3.7E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS06400 de7ffecbce658cf559e45544cbd967bb 966 Gene3D G3DSA:1.25.40.10 612 781 3.7E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS01915 cf7a7b5a32407a80eecfcaf81302b34c 252 Pfam PF00975 Thioesterase domain 25 245 2.3E-45 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS01915 cf7a7b5a32407a80eecfcaf81302b34c 252 SMART SM00824 Thioesterase 27 247 3.1E-5 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD11_RS01915 cf7a7b5a32407a80eecfcaf81302b34c 252 SUPERFAMILY SSF53474 4 247 6.93E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01915 cf7a7b5a32407a80eecfcaf81302b34c 252 Gene3D G3DSA:3.40.50.1820 19 248 3.6E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30445 be47935313fae83cfe9fd01ec5791d67 335 Gene3D G3DSA:2.80.10.50 208 332 3.3E-31 T 06-07-2017 SMD11_RS30445 be47935313fae83cfe9fd01ec5791d67 335 SUPERFAMILY SSF50370 210 332 2.48E-31 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS30445 be47935313fae83cfe9fd01ec5791d67 335 Pfam PF00652 Ricin-type beta-trefoil lectin domain 211 330 5.5E-24 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS30445 be47935313fae83cfe9fd01ec5791d67 335 SMART SM00458 207 333 5.5E-22 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS15895 0bc0e40626546f393b2acde5c42d4487 249 SUPERFAMILY SSF51735 3 230 1.69E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS15895 0bc0e40626546f393b2acde5c42d4487 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 3.4E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS15895 0bc0e40626546f393b2acde5c42d4487 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.4E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS15895 0bc0e40626546f393b2acde5c42d4487 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 3.4E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS15895 0bc0e40626546f393b2acde5c42d4487 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 3.4E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS15895 0bc0e40626546f393b2acde5c42d4487 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 3.4E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS15895 0bc0e40626546f393b2acde5c42d4487 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 1.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS15895 0bc0e40626546f393b2acde5c42d4487 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 1.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS15895 0bc0e40626546f393b2acde5c42d4487 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 1.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS15895 0bc0e40626546f393b2acde5c42d4487 249 Gene3D G3DSA:3.40.50.720 3 230 1.5E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS15895 0bc0e40626546f393b2acde5c42d4487 249 Pfam PF00106 short chain dehydrogenase 4 180 6.0E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS25130 66f71593d3508efc851fed7b4fcb86d6 258 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 4 256 39.29 T 06-07-2017 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25130 66f71593d3508efc851fed7b4fcb86d6 258 Gene3D G3DSA:3.20.20.70 4 255 9.2E-105 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS25130 66f71593d3508efc851fed7b4fcb86d6 258 Pfam PF00121 Triosephosphate isomerase 7 253 1.1E-86 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25130 66f71593d3508efc851fed7b4fcb86d6 258 SUPERFAMILY SSF51351 4 255 2.49E-91 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25130 66f71593d3508efc851fed7b4fcb86d6 258 ProSitePatterns PS00171 Triosephosphate isomerase active site. 171 181 - T 06-07-2017 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25130 66f71593d3508efc851fed7b4fcb86d6 258 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 245 5.3E-54 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS20565 a6d704b43c9c14aa0fc646b98e5baaec 226 SUPERFAMILY SSF52172 1 125 4.84E-40 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS20565 a6d704b43c9c14aa0fc646b98e5baaec 226 SMART SM00862 147 223 5.4E-28 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS20565 a6d704b43c9c14aa0fc646b98e5baaec 226 Pfam PF00072 Response regulator receiver domain 4 114 3.2E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS20565 a6d704b43c9c14aa0fc646b98e5baaec 226 SUPERFAMILY SSF46894 127 224 4.54E-30 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS20565 a6d704b43c9c14aa0fc646b98e5baaec 226 Gene3D G3DSA:1.10.10.10 125 225 3.3E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20565 a6d704b43c9c14aa0fc646b98e5baaec 226 Gene3D G3DSA:3.40.50.2300 2 121 3.7E-39 T 06-07-2017 SMD11_RS20565 a6d704b43c9c14aa0fc646b98e5baaec 226 SMART SM00448 2 113 3.0E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS20565 a6d704b43c9c14aa0fc646b98e5baaec 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 7.4E-28 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS16540 f60e5f47513081fee367610a5dce97cd 379 Pfam PF01551 Peptidase family M23 271 368 4.1E-27 T 06-07-2017 IPR016047 Peptidase M23 SMD11_RS16540 f60e5f47513081fee367610a5dce97cd 379 Gene3D G3DSA:2.70.70.10 239 373 4.6E-41 T 06-07-2017 SMD11_RS16540 f60e5f47513081fee367610a5dce97cd 379 SUPERFAMILY SSF51261 238 372 3.3E-43 T 06-07-2017 IPR011055 Duplicated hybrid motif SMD11_RS29520 0fc06ab6dfd3bd2c7286c5c021163c66 247 SUPERFAMILY SSF46689 30 94 3.44E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS29520 0fc06ab6dfd3bd2c7286c5c021163c66 247 Pfam PF00440 Bacterial regulatory proteins, tetR family 43 84 9.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS29520 0fc06ab6dfd3bd2c7286c5c021163c66 247 SUPERFAMILY SSF48498 102 245 2.22E-25 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS29520 0fc06ab6dfd3bd2c7286c5c021163c66 247 Gene3D G3DSA:1.10.357.10 89 245 3.3E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS29520 0fc06ab6dfd3bd2c7286c5c021163c66 247 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 97 244 3.1E-19 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD11_RS29520 0fc06ab6dfd3bd2c7286c5c021163c66 247 Gene3D G3DSA:1.10.10.60 26 88 1.5E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS11915 2bd16c0e2898b7f7cc199a99d439194a 408 SUPERFAMILY SSF55874 307 391 5.59E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS11915 2bd16c0e2898b7f7cc199a99d439194a 408 Gene3D G3DSA:3.30.565.10 302 350 2.4E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS11915 2bd16c0e2898b7f7cc199a99d439194a 408 Pfam PF07730 Histidine kinase 193 259 1.5E-18 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS25145 1d8c7f555980967db48104cc5d216cad 550 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 497 514 - T 06-07-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25145 1d8c7f555980967db48104cc5d216cad 550 Gene3D G3DSA:1.10.1390.10 502 548 2.8E-20 T 06-07-2017 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25145 1d8c7f555980967db48104cc5d216cad 550 SUPERFAMILY SSF53697 9 548 7.51E-207 T 06-07-2017 SMD11_RS25145 1d8c7f555980967db48104cc5d216cad 550 Pfam PF00342 Phosphoglucose isomerase 54 541 3.2E-218 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25145 1d8c7f555980967db48104cc5d216cad 550 Gene3D G3DSA:3.40.50.10490 149 187 3.7E-157 T 06-07-2017 SMD11_RS25145 1d8c7f555980967db48104cc5d216cad 550 Gene3D G3DSA:3.40.50.10490 267 501 3.7E-157 T 06-07-2017 SMD11_RS25145 1d8c7f555980967db48104cc5d216cad 550 Gene3D G3DSA:3.40.50.10490 9 104 3.7E-157 T 06-07-2017 SMD11_RS25145 1d8c7f555980967db48104cc5d216cad 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 152 171 3.7E-54 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25145 1d8c7f555980967db48104cc5d216cad 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 342 363 3.7E-54 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25145 1d8c7f555980967db48104cc5d216cad 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 497 510 3.7E-54 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25145 1d8c7f555980967db48104cc5d216cad 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 265 283 3.7E-54 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25145 1d8c7f555980967db48104cc5d216cad 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 465 483 3.7E-54 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25145 1d8c7f555980967db48104cc5d216cad 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 483 497 3.7E-54 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS25145 1d8c7f555980967db48104cc5d216cad 550 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 48 524 41.171 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SMD11_RS28025 15a92f67bbdd092f20ce7b552c5e798e 214 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 69 85 - T 06-07-2017 IPR033693 Pyroglutamyl peptidase I, Glu active site SMD11_RS28025 15a92f67bbdd092f20ce7b552c5e798e 214 SUPERFAMILY SSF53182 3 214 3.27E-68 T 06-07-2017 SMD11_RS28025 15a92f67bbdd092f20ce7b552c5e798e 214 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 3 211 3.3E-80 T 06-07-2017 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 SMD11_RS28025 15a92f67bbdd092f20ce7b552c5e798e 214 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 198 39.267 T 06-07-2017 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 SMD11_RS28025 15a92f67bbdd092f20ce7b552c5e798e 214 Pfam PF01470 Pyroglutamyl peptidase 3 199 1.8E-72 T 06-07-2017 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like SMD11_RS28025 15a92f67bbdd092f20ce7b552c5e798e 214 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 130 144 - T 06-07-2017 IPR033694 Pyroglutamyl peptidase I, Cys active site SMD11_RS28025 15a92f67bbdd092f20ce7b552c5e798e 214 PIRSF PIRSF015592 1 212 1.9E-76 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SMD11_RS28025 15a92f67bbdd092f20ce7b552c5e798e 214 Gene3D G3DSA:3.40.630.20 3 209 1.3E-63 T 06-07-2017 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like SMD11_RS28025 15a92f67bbdd092f20ce7b552c5e798e 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 3.9E-46 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SMD11_RS28025 15a92f67bbdd092f20ce7b552c5e798e 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 3.9E-46 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SMD11_RS28025 15a92f67bbdd092f20ce7b552c5e798e 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 3.9E-46 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SMD11_RS28025 15a92f67bbdd092f20ce7b552c5e798e 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 3.9E-46 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SMD11_RS28025 15a92f67bbdd092f20ce7b552c5e798e 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 162 174 3.9E-46 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SMD11_RS26835 1e2265faff7165d47ad51573e8611405 215 Gene3D G3DSA:3.40.630.30 14 130 7.0E-4 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS26835 1e2265faff7165d47ad51573e8611405 215 SUPERFAMILY SSF55729 3 170 4.7E-9 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS18615 3c1595ecff973e57a10a28d579602131 394 SUPERFAMILY SSF56529 107 388 4.06E-87 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD11_RS18615 3c1595ecff973e57a10a28d579602131 394 Gene3D G3DSA:2.30.30.230 9 107 3.0E-24 T 06-07-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 SMD11_RS18615 3c1595ecff973e57a10a28d579602131 394 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 10 388 5.1E-115 T 06-07-2017 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 SMD11_RS18615 3c1595ecff973e57a10a28d579602131 394 Pfam PF09298 Fumarylacetoacetase N-terminal 20 105 5.1E-16 T 06-07-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 SMD11_RS18615 3c1595ecff973e57a10a28d579602131 394 SUPERFAMILY SSF63433 8 105 1.44E-19 T 06-07-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 SMD11_RS18615 3c1595ecff973e57a10a28d579602131 394 Gene3D G3DSA:3.90.850.10 108 382 1.8E-98 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD11_RS18615 3c1595ecff973e57a10a28d579602131 394 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 111 386 2.4E-54 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD11_RS28430 6553955f505abf967da1a8ffe1850c2b 106 SUPERFAMILY SSF54427 5 101 8.03E-9 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS28430 6553955f505abf967da1a8ffe1850c2b 106 Gene3D G3DSA:3.10.450.50 5 102 2.8E-7 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS25530 8b5501f9a4dddf55aa1ded407d632a3d 363 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 36 363 2.6E-110 T 06-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS25530 8b5501f9a4dddf55aa1ded407d632a3d 363 Pfam PF13353 4Fe-4S single cluster domain 52 138 7.9E-7 T 06-07-2017 SMD11_RS25530 8b5501f9a4dddf55aa1ded407d632a3d 363 Pfam PF06463 Molybdenum Cofactor Synthesis C 217 343 2.6E-37 T 06-07-2017 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS25530 8b5501f9a4dddf55aa1ded407d632a3d 363 SUPERFAMILY SSF102114 37 311 7.59E-74 T 06-07-2017 SMD11_RS25530 8b5501f9a4dddf55aa1ded407d632a3d 363 SMART SM00729 45 247 9.9E-12 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD11_RS25530 8b5501f9a4dddf55aa1ded407d632a3d 363 Gene3D G3DSA:3.20.20.70 36 340 1.8E-80 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS25530 8b5501f9a4dddf55aa1ded407d632a3d 363 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 51 62 - T 06-07-2017 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS25530 8b5501f9a4dddf55aa1ded407d632a3d 363 Pfam PF04055 Radical SAM superfamily 50 211 3.9E-34 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS25530 8b5501f9a4dddf55aa1ded407d632a3d 363 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 36 363 41.1 T 06-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 SMD11_RS13930 8ccaa6f13d1c925451b02a48c497e0f2 486 SUPERFAMILY SSF53756 11 484 4.08E-112 T 06-07-2017 SMD11_RS13930 8ccaa6f13d1c925451b02a48c497e0f2 486 Gene3D G3DSA:3.40.50.2000 274 466 7.3E-59 T 06-07-2017 SMD11_RS13930 8ccaa6f13d1c925451b02a48c497e0f2 486 Gene3D G3DSA:3.40.50.2000 11 273 1.4E-61 T 06-07-2017 SMD11_RS13930 8ccaa6f13d1c925451b02a48c497e0f2 486 Pfam PF00982 Glycosyltransferase family 20 12 482 1.3E-108 T 06-07-2017 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 SMD11_RS00595 325662e1d89aadd27332f3d4f2b07008 407 SUPERFAMILY SSF53901 6 251 5.42E-70 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00595 325662e1d89aadd27332f3d4f2b07008 407 SMART SM00825 Beta-ketoacyl synthase 7 407 1.7E-17 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS00595 325662e1d89aadd27332f3d4f2b07008 407 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 246 1.0E-52 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS00595 325662e1d89aadd27332f3d4f2b07008 407 Gene3D G3DSA:3.40.47.10 6 257 5.5E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00595 325662e1d89aadd27332f3d4f2b07008 407 Gene3D G3DSA:3.40.47.10 262 405 1.4E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00595 325662e1d89aadd27332f3d4f2b07008 407 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS00595 325662e1d89aadd27332f3d4f2b07008 407 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 365 2.0E-30 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS00595 325662e1d89aadd27332f3d4f2b07008 407 SUPERFAMILY SSF53901 214 405 2.23E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS04720 d59fc76170430c75e9e5bf5f2b08756d 1696 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 1329 1368 2.5E-4 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS04720 d59fc76170430c75e9e5bf5f2b08756d 1696 Gene3D G3DSA:3.40.50.300 1295 1470 1.4E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04720 d59fc76170430c75e9e5bf5f2b08756d 1696 Pfam PF12458 ATPase involved in DNA repair 74 536 3.7E-169 T 06-07-2017 IPR020958 DUF3686 SMD11_RS04720 d59fc76170430c75e9e5bf5f2b08756d 1696 SUPERFAMILY SSF52540 1319 1453 3.53E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29420 49d6e2bb2a8e629235674f51b26e3927 210 Gene3D G3DSA:3.60.15.10 10 204 1.0E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS29420 49d6e2bb2a8e629235674f51b26e3927 210 Pfam PF00753 Metallo-beta-lactamase superfamily 26 189 1.2E-25 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS29420 49d6e2bb2a8e629235674f51b26e3927 210 SMART SM00849 25 189 6.3E-40 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS29420 49d6e2bb2a8e629235674f51b26e3927 210 SUPERFAMILY SSF56281 11 202 7.34E-48 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS28000 64c9078771bfb52b037e8d59e662df37 241 SUPERFAMILY SSF50891 118 240 2.62E-40 T 06-07-2017 IPR029000 Cyclophilin-like domain SMD11_RS28000 64c9078771bfb52b037e8d59e662df37 241 SMART SM00796 38 229 7.6E-77 T 06-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D SMD11_RS28000 64c9078771bfb52b037e8d59e662df37 241 Gene3D G3DSA:2.40.100.10 118 240 3.6E-48 T 06-07-2017 IPR029000 Cyclophilin-like domain SMD11_RS28000 64c9078771bfb52b037e8d59e662df37 241 Pfam PF02682 Allophanate hydrolase subunit 1 39 229 6.5E-60 T 06-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D SMD11_RS20220 ba2e984ab0091e47723ad779fc1f9d25 262 Gene3D G3DSA:3.40.50.300 23 239 8.9E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20220 ba2e984ab0091e47723ad779fc1f9d25 262 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS20220 ba2e984ab0091e47723ad779fc1f9d25 262 SMART SM00382 49 235 1.9E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS20220 ba2e984ab0091e47723ad779fc1f9d25 262 SUPERFAMILY SSF52540 23 239 9.41E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20220 ba2e984ab0091e47723ad779fc1f9d25 262 Pfam PF00005 ABC transporter 40 186 1.6E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS16485 df1cb1cdb9b228664fcc9140c63d63a1 303 SUPERFAMILY SSF52540 4 216 1.15E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16485 df1cb1cdb9b228664fcc9140c63d63a1 303 Gene3D G3DSA:3.40.50.300 4 216 2.5E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16485 df1cb1cdb9b228664fcc9140c63d63a1 303 SMART SM00382 27 204 1.3E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS16485 df1cb1cdb9b228664fcc9140c63d63a1 303 Pfam PF00005 ABC transporter 20 157 6.6E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS16485 df1cb1cdb9b228664fcc9140c63d63a1 303 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS15010 eea37a4df950053bc06a59308bad669a 194 Pfam PF04978 Protein of unknown function (DUF664) 16 166 3.7E-45 T 06-07-2017 IPR007061 Protein of unknown function DUF664 SMD11_RS15010 eea37a4df950053bc06a59308bad669a 194 Gene3D G3DSA:1.20.120.450 8 168 1.3E-41 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase SMD11_RS15010 eea37a4df950053bc06a59308bad669a 194 SUPERFAMILY SSF109854 9 165 4.12E-38 T 06-07-2017 SMD11_RS32890 2365a8e4fdf62435fe520ec674acadf1 429 SUPERFAMILY SSF48264 25 411 7.2E-81 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS32890 2365a8e4fdf62435fe520ec674acadf1 429 Pfam PF00067 Cytochrome P450 225 386 1.6E-20 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS32890 2365a8e4fdf62435fe520ec674acadf1 429 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 353 362 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS32890 2365a8e4fdf62435fe520ec674acadf1 429 Gene3D G3DSA:1.10.630.10 15 412 5.0E-102 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS32890 2365a8e4fdf62435fe520ec674acadf1 429 PRINTS PR00359 B-class P450 signature 330 345 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32890 2365a8e4fdf62435fe520ec674acadf1 429 PRINTS PR00359 B-class P450 signature 98 109 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32890 2365a8e4fdf62435fe520ec674acadf1 429 PRINTS PR00359 B-class P450 signature 161 176 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32890 2365a8e4fdf62435fe520ec674acadf1 429 PRINTS PR00359 B-class P450 signature 360 371 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32890 2365a8e4fdf62435fe520ec674acadf1 429 PRINTS PR00359 B-class P450 signature 351 360 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32890 2365a8e4fdf62435fe520ec674acadf1 429 PRINTS PR00359 B-class P450 signature 302 329 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32890 2365a8e4fdf62435fe520ec674acadf1 429 PRINTS PR00359 B-class P450 signature 285 296 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS26545 bf29941f2829e7d5dbc65336a7636ec8 406 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 1 406 5.1E-203 T 06-07-2017 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 SMD11_RS26545 bf29941f2829e7d5dbc65336a7636ec8 406 Pfam PF03136 Pup-ligase protein 1 376 4.7E-150 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 SMD11_RS26545 bf29941f2829e7d5dbc65336a7636ec8 406 PIRSF PIRSF018077 1 406 8.5E-169 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 SMD11_RS33445 022b7f33b10c3689a051b88204025312 567 Gene3D G3DSA:3.20.20.140 211 512 2.0E-24 T 06-07-2017 SMD11_RS33445 022b7f33b10c3689a051b88204025312 567 Gene3D G3DSA:3.20.20.140 67 86 2.0E-24 T 06-07-2017 SMD11_RS33445 022b7f33b10c3689a051b88204025312 567 Gene3D G3DSA:2.30.40.10 521 564 4.2E-18 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS33445 022b7f33b10c3689a051b88204025312 567 Gene3D G3DSA:2.30.40.10 5 65 4.2E-18 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS33445 022b7f33b10c3689a051b88204025312 567 SUPERFAMILY SSF51338 521 563 2.55E-23 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS33445 022b7f33b10c3689a051b88204025312 567 SUPERFAMILY SSF51338 3 64 2.55E-23 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS33445 022b7f33b10c3689a051b88204025312 567 Pfam PF07969 Amidohydrolase family 52 562 2.8E-95 T 06-07-2017 IPR013108 Amidohydrolase 3 SMD11_RS33445 022b7f33b10c3689a051b88204025312 567 SUPERFAMILY SSF51556 205 522 5.67E-28 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS33445 022b7f33b10c3689a051b88204025312 567 SUPERFAMILY SSF51556 63 124 5.67E-28 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS25375 f9928d95764b2617f0a156e1e2b107e8 202 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 22 202 1.8E-59 T 06-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 SMD11_RS25375 f9928d95764b2617f0a156e1e2b107e8 202 Gene3D G3DSA:3.40.50.300 10 202 6.7E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25375 f9928d95764b2617f0a156e1e2b107e8 202 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 19 202 5.1E-69 T 06-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 SMD11_RS25375 f9928d95764b2617f0a156e1e2b107e8 202 SUPERFAMILY SSF52540 12 202 1.73E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25375 f9928d95764b2617f0a156e1e2b107e8 202 PIRSF PIRSF015617 1 202 5.8E-66 T 06-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 SMD11_RS08140 22213ca8cf143223d6423e71a059687c 109 Pfam PF00550 Phosphopantetheine attachment site 41 91 2.5E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08140 22213ca8cf143223d6423e71a059687c 109 Gene3D G3DSA:1.10.1200.10 22 93 3.5E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS08140 22213ca8cf143223d6423e71a059687c 109 SUPERFAMILY SSF47336 22 103 2.22E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS28255 fe12073a734e732ef05b1c3973100dfe 156 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 16 101 7.1E-16 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD11_RS28255 fe12073a734e732ef05b1c3973100dfe 156 SUPERFAMILY SSF50475 7 151 2.62E-29 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS28255 fe12073a734e732ef05b1c3973100dfe 156 Gene3D G3DSA:2.30.110.10 10 152 2.0E-33 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS08200 c4b319fbd539feb194b17430fcce343f 307 PIRSF PIRSF002936 5 307 5.4E-148 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMD11_RS08200 c4b319fbd539feb194b17430fcce343f 307 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 35 262 2.4E-60 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 SMD11_RS08200 c4b319fbd539feb194b17430fcce343f 307 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 14 307 1.8E-149 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMD11_RS08200 c4b319fbd539feb194b17430fcce343f 307 SUPERFAMILY SSF52402 12 214 1.78E-71 T 06-07-2017 SMD11_RS08200 c4b319fbd539feb194b17430fcce343f 307 Gene3D G3DSA:3.40.50.620 10 215 5.0E-60 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS08200 c4b319fbd539feb194b17430fcce343f 307 Gene3D G3DSA:3.40.50.620 249 258 5.0E-60 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS08200 c4b319fbd539feb194b17430fcce343f 307 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 9 307 55.714 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMD11_RS16775 09e48fc33d435e758358d79f3cad9941 96 Gene3D G3DSA:3.30.70.60 1 94 1.3E-34 T 06-07-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 SMD11_RS16775 09e48fc33d435e758358d79f3cad9941 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 92 1.7E-25 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16775 09e48fc33d435e758358d79f3cad9941 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 06-07-2017 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMD11_RS16775 09e48fc33d435e758358d79f3cad9941 96 SUPERFAMILY SSF54995 1 94 3.79E-32 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16775 09e48fc33d435e758358d79f3cad9941 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 21.989 T 06-07-2017 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMD11_RS16775 09e48fc33d435e758358d79f3cad9941 96 Pfam PF01250 Ribosomal protein S6 3 92 2.7E-28 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS21055 41c71e0a64d5ebb521e93305a0d7c1e9 510 SUPERFAMILY SSF47741 407 475 8.9E-27 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD11_RS21055 41c71e0a64d5ebb521e93305a0d7c1e9 510 Pfam PF01799 [2Fe-2S] binding domain 396 468 5.7E-24 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD11_RS21055 41c71e0a64d5ebb521e93305a0d7c1e9 510 SUPERFAMILY SSF54292 324 400 3.91E-18 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS21055 41c71e0a64d5ebb521e93305a0d7c1e9 510 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 362 370 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMD11_RS21055 41c71e0a64d5ebb521e93305a0d7c1e9 510 Gene3D G3DSA:1.10.150.120 398 496 3.2E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD11_RS21055 41c71e0a64d5ebb521e93305a0d7c1e9 510 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 339 377 2.0E-4 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS21055 41c71e0a64d5ebb521e93305a0d7c1e9 510 Gene3D G3DSA:3.10.20.30 325 397 3.4E-25 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS16790 5ad06cbbe922572b683b15bf5cf4fe69 343 SUPERFAMILY SSF51419 10 176 5.42E-14 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS16790 5ad06cbbe922572b683b15bf5cf4fe69 343 Gene3D G3DSA:3.20.20.10 25 172 5.7E-13 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS16790 5ad06cbbe922572b683b15bf5cf4fe69 343 Pfam PF01168 Alanine racemase, N-terminal domain 8 174 2.2E-13 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS24725 ecf9229cfe8f51d2e194fcbb12529170 126 SUPERFAMILY SSF141734 18 121 1.27E-47 T 06-07-2017 SMD11_RS24725 ecf9229cfe8f51d2e194fcbb12529170 126 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 45 117 4.9E-34 T 06-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 SMD11_RS24725 ecf9229cfe8f51d2e194fcbb12529170 126 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 68 122 1.0E-22 T 06-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 SMD11_RS24725 ecf9229cfe8f51d2e194fcbb12529170 126 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 19 122 31.934 T 06-07-2017 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 SMD11_RS13170 2b93b68d1b3615e8519d674d0634ad08 500 Pfam PF00171 Aldehyde dehydrogenase family 13 486 2.6E-163 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS13170 2b93b68d1b3615e8519d674d0634ad08 500 Gene3D G3DSA:3.40.309.10 268 461 4.9E-67 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS13170 2b93b68d1b3615e8519d674d0634ad08 500 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS13170 2b93b68d1b3615e8519d674d0634ad08 500 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 284 295 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS13170 2b93b68d1b3615e8519d674d0634ad08 500 SUPERFAMILY SSF53720 7 491 1.24E-161 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS13170 2b93b68d1b3615e8519d674d0634ad08 500 Gene3D G3DSA:3.40.605.10 8 267 8.5E-91 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS11320 b9c308a4d53b42e4d27b2b146e6f4447 184 Pfam PF00583 Acetyltransferase (GNAT) family 66 161 1.9E-6 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS11320 b9c308a4d53b42e4d27b2b146e6f4447 184 Gene3D G3DSA:3.40.630.30 15 167 1.0E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS11320 b9c308a4d53b42e4d27b2b146e6f4447 184 SUPERFAMILY SSF55729 15 171 1.31E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS00820 dbcc5b642c9e4c6790b9c60f68672a1d 297 Pfam PF13489 Methyltransferase domain 88 224 1.8E-11 T 06-07-2017 SMD11_RS00820 dbcc5b642c9e4c6790b9c60f68672a1d 297 Gene3D G3DSA:3.40.50.150 61 226 5.6E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS00820 dbcc5b642c9e4c6790b9c60f68672a1d 297 SUPERFAMILY SSF53335 38 223 1.84E-23 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS04890 d1e003c9d1d1ef73046951f8a37bdf52 288 SUPERFAMILY SSF56059 14 198 7.28E-13 T 06-07-2017 SMD11_RS04890 d1e003c9d1d1ef73046951f8a37bdf52 288 Gene3D G3DSA:3.30.470.20 10 30 4.8E-6 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS04890 d1e003c9d1d1ef73046951f8a37bdf52 288 Gene3D G3DSA:3.30.470.20 102 197 4.8E-6 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS04855 cd5137160bdce04c7f49c479933298a1 891 SUPERFAMILY SSF56112 177 405 3.69E-33 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS04855 cd5137160bdce04c7f49c479933298a1 891 PRINTS PR01950 LanC-like protein superfamily signature 668 684 6.4E-11 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS04855 cd5137160bdce04c7f49c479933298a1 891 PRINTS PR01950 LanC-like protein superfamily signature 834 851 6.4E-11 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS04855 cd5137160bdce04c7f49c479933298a1 891 PRINTS PR01950 LanC-like protein superfamily signature 776 789 6.4E-11 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS04855 cd5137160bdce04c7f49c479933298a1 891 PRINTS PR01950 LanC-like protein superfamily signature 604 619 6.4E-11 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS04855 cd5137160bdce04c7f49c479933298a1 891 PRINTS PR01950 LanC-like protein superfamily signature 730 750 6.4E-11 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS04855 cd5137160bdce04c7f49c479933298a1 891 Gene3D G3DSA:1.50.10.10 731 813 5.2E-4 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 SMD11_RS04855 cd5137160bdce04c7f49c479933298a1 891 Gene3D G3DSA:3.30.200.20 177 256 6.0E-8 T 06-07-2017 SMD11_RS04855 cd5137160bdce04c7f49c479933298a1 891 Gene3D G3DSA:1.10.510.10 257 406 1.5E-19 T 06-07-2017 SMD11_RS04855 cd5137160bdce04c7f49c479933298a1 891 Pfam PF00069 Protein kinase domain 192 407 2.8E-15 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS04855 cd5137160bdce04c7f49c479933298a1 891 SMART SM00220 181 503 1.6E-9 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS04855 cd5137160bdce04c7f49c479933298a1 891 SUPERFAMILY SSF158745 509 856 1.31E-44 T 06-07-2017 SMD11_RS04855 cd5137160bdce04c7f49c479933298a1 891 SMART SM01260 510 863 1.0E-38 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS04855 cd5137160bdce04c7f49c479933298a1 891 Pfam PF05147 Lanthionine synthetase C-like protein 519 857 3.3E-36 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS31200 ee2620c3b859f32355a45a43cda50900 331 Gene3D G3DSA:3.40.50.1980 36 162 4.5E-32 T 06-07-2017 SMD11_RS31200 ee2620c3b859f32355a45a43cda50900 331 Pfam PF01497 Periplasmic binding protein 86 286 1.3E-24 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD11_RS31200 ee2620c3b859f32355a45a43cda50900 331 Gene3D G3DSA:3.40.50.1980 163 327 2.7E-23 T 06-07-2017 SMD11_RS31200 ee2620c3b859f32355a45a43cda50900 331 SUPERFAMILY SSF53807 38 324 3.6E-52 T 06-07-2017 SMD11_RS12160 29ed4c1ed154cb7217cedc9048dee16f 118 Pfam PF02467 Transcription factor WhiB 27 95 1.1E-21 T 06-07-2017 IPR003482 Transcription factor WhiB SMD11_RS12160 29ed4c1ed154cb7217cedc9048dee16f 118 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 8 103 18.398 T 06-07-2017 IPR003482 Transcription factor WhiB SMD11_RS05850 b2e13cf5b1b10beee6744675e677c298 494 Pfam PF13520 Amino acid permease 30 427 1.5E-52 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS05850 b2e13cf5b1b10beee6744675e677c298 494 PIRSF PIRSF006060 20 475 2.4E-68 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS12125 8f5a1e3d2c4ffc09d24334b3a54ed958 334 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 8 287 1.1E-95 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 SMD11_RS12125 8f5a1e3d2c4ffc09d24334b3a54ed958 334 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 7 290 36.478 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 SMD11_RS12125 8f5a1e3d2c4ffc09d24334b3a54ed958 334 Pfam PF02401 LytB protein 9 286 3.7E-88 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 SMD11_RS26890 9775d675702b651f3fd019712cdf3d52 431 SUPERFAMILY SSF53383 34 427 1.48E-94 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS26890 9775d675702b651f3fd019712cdf3d52 431 Gene3D G3DSA:3.40.640.10 77 305 1.5E-69 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS26890 9775d675702b651f3fd019712cdf3d52 431 Gene3D G3DSA:3.90.1150.10 306 430 8.1E-40 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS26890 9775d675702b651f3fd019712cdf3d52 431 Pfam PF00155 Aminotransferase class I and II 61 421 3.0E-47 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS27385 78b186fc9c2364da8c4a82d6a23196b2 196 Gene3D G3DSA:3.30.63.10 63 99 8.8E-26 T 06-07-2017 SMD11_RS27385 78b186fc9c2364da8c4a82d6a23196b2 196 Gene3D G3DSA:3.40.50.300 100 195 4.9E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27385 78b186fc9c2364da8c4a82d6a23196b2 196 Gene3D G3DSA:3.40.50.300 16 28 4.9E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27385 78b186fc9c2364da8c4a82d6a23196b2 196 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 19 195 1.8E-69 T 06-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 SMD11_RS27385 78b186fc9c2364da8c4a82d6a23196b2 196 Hamap MF_00328 Guanylate kinase [gmk]. 16 196 34.17 T 06-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 SMD11_RS27385 78b186fc9c2364da8c4a82d6a23196b2 196 SMART SM00072 17 196 8.7E-57 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit SMD11_RS27385 78b186fc9c2364da8c4a82d6a23196b2 196 Pfam PF00625 Guanylate kinase 18 194 1.9E-42 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit SMD11_RS27385 78b186fc9c2364da8c4a82d6a23196b2 196 SUPERFAMILY SSF52540 16 195 2.1E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27385 78b186fc9c2364da8c4a82d6a23196b2 196 Gene3D G3DSA:3.40.50.300 29 62 2.8E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27385 78b186fc9c2364da8c4a82d6a23196b2 196 ProSitePatterns PS00856 Guanylate kinase-like signature. 52 69 - T 06-07-2017 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 SMD11_RS15335 884b0ee00b873ec940c78c90ef03b7c6 385 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 5 343 1.4E-156 T 06-07-2017 IPR022399 Helicase/secretion neighbourhood ATPase SMD11_RS15335 884b0ee00b873ec940c78c90ef03b7c6 385 SUPERFAMILY SSF52540 43 351 4.72E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15335 884b0ee00b873ec940c78c90ef03b7c6 385 Pfam PF00437 Type II/IV secretion system protein 57 331 3.5E-78 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SMD11_RS15335 884b0ee00b873ec940c78c90ef03b7c6 385 Gene3D G3DSA:3.40.50.300 155 370 1.5E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15335 884b0ee00b873ec940c78c90ef03b7c6 385 Gene3D G3DSA:3.30.450.90 53 148 1.1E-25 T 06-07-2017 SMD11_RS08650 f9f3eb1f4996c0657b244cb44296900d 364 Gene3D G3DSA:3.40.50.300 4 197 3.9E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08650 f9f3eb1f4996c0657b244cb44296900d 364 Gene3D G3DSA:3.30.1220.10 229 343 4.0E-17 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD11_RS08650 f9f3eb1f4996c0657b244cb44296900d 364 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 252 343 2.0E-22 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD11_RS08650 f9f3eb1f4996c0657b244cb44296900d 364 SUPERFAMILY SSF52540 5 174 2.63E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08650 f9f3eb1f4996c0657b244cb44296900d 364 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 7 175 7.1E-44 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain SMD11_RS08650 f9f3eb1f4996c0657b244cb44296900d 364 SUPERFAMILY SSF90002 252 343 4.18E-18 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD11_RS08650 f9f3eb1f4996c0657b244cb44296900d 364 SMART SM00833 251 343 3.3E-17 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal SMD11_RS28180 77225636d77192e75f9e14b327da7eae 157 SUPERFAMILY SSF103256 3 136 2.22E-46 T 06-07-2017 IPR003729 Bifunctional nuclease domain GO:0004518 SMD11_RS28180 77225636d77192e75f9e14b327da7eae 157 Pfam PF02577 Bifunctional nuclease 6 128 2.7E-45 T 06-07-2017 IPR003729 Bifunctional nuclease domain GO:0004518 SMD11_RS31680 5b6a65e6288b77b427d3a2c5bc3a4e84 149 SUPERFAMILY SSF46785 4 136 3.86E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS31680 5b6a65e6288b77b427d3a2c5bc3a4e84 149 Gene3D G3DSA:1.10.10.10 4 103 1.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS31680 5b6a65e6288b77b427d3a2c5bc3a4e84 149 Pfam PF01638 HxlR-like helix-turn-helix 15 101 2.0E-20 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type SMD11_RS30700 61c584a5d93377505aaefa80f3f0ad93 329 Gene3D G3DSA:3.40.30.10 1 49 5.0E-4 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS30700 61c584a5d93377505aaefa80f3f0ad93 329 Pfam PF01497 Periplasmic binding protein 59 303 3.4E-21 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD11_RS30700 61c584a5d93377505aaefa80f3f0ad93 329 Gene3D G3DSA:3.40.50.1980 50 158 3.2E-28 T 06-07-2017 SMD11_RS30700 61c584a5d93377505aaefa80f3f0ad93 329 SUPERFAMILY SSF53807 41 320 3.1E-49 T 06-07-2017 SMD11_RS30700 61c584a5d93377505aaefa80f3f0ad93 329 Gene3D G3DSA:3.40.50.1980 159 328 2.5E-41 T 06-07-2017 SMD11_RS30700 61c584a5d93377505aaefa80f3f0ad93 329 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 107 122 5.2E-5 T 06-07-2017 IPR008091 Ferrichrome-binding periplasmic protein SMD11_RS30700 61c584a5d93377505aaefa80f3f0ad93 329 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 307 320 5.2E-5 T 06-07-2017 IPR008091 Ferrichrome-binding periplasmic protein SMD11_RS30700 61c584a5d93377505aaefa80f3f0ad93 329 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 76 94 5.2E-5 T 06-07-2017 IPR008091 Ferrichrome-binding periplasmic protein SMD11_RS24430 bb952bc8bd5328d201a3b75d96ea942e 507 SUPERFAMILY SSF51905 2 319 1.15E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24430 bb952bc8bd5328d201a3b75d96ea942e 507 SUPERFAMILY SSF51905 460 498 1.15E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24430 bb952bc8bd5328d201a3b75d96ea942e 507 Gene3D G3DSA:3.50.50.60 217 297 9.1E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24430 bb952bc8bd5328d201a3b75d96ea942e 507 Gene3D G3DSA:3.50.50.60 442 497 9.1E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24430 bb952bc8bd5328d201a3b75d96ea942e 507 Gene3D G3DSA:3.50.50.60 2 85 9.1E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24430 bb952bc8bd5328d201a3b75d96ea942e 507 Gene3D G3DSA:3.50.50.60 135 136 9.1E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24430 bb952bc8bd5328d201a3b75d96ea942e 507 Pfam PF01593 Flavin containing amine oxidoreductase 14 295 4.5E-18 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 Gene3D G3DSA:1.10.630.10 14 395 1.3E-119 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 Pfam PF00067 Cytochrome P450 206 364 4.1E-25 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 SUPERFAMILY SSF48264 18 394 5.89E-95 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 PRINTS PR00385 P450 superfamily signature 267 278 5.1E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 PRINTS PR00385 P450 superfamily signature 342 353 5.1E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 PRINTS PR00385 P450 superfamily signature 333 342 5.1E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 PRINTS PR00385 P450 superfamily signature 232 249 5.1E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 335 344 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 PRINTS PR00359 B-class P450 signature 267 278 7.0E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 PRINTS PR00359 B-class P450 signature 154 169 7.0E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 PRINTS PR00359 B-class P450 signature 333 342 7.0E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 PRINTS PR00359 B-class P450 signature 312 327 7.0E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 PRINTS PR00359 B-class P450 signature 137 153 7.0E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 PRINTS PR00359 B-class P450 signature 342 353 7.0E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 PRINTS PR00359 B-class P450 signature 284 311 7.0E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 PRINTS PR00359 B-class P450 signature 90 101 7.0E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS02790 bebda0eb7f8a715231eede318b3588d5 396 PRINTS PR00359 B-class P450 signature 191 213 7.0E-57 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS13340 d85af77ac6d2fdfe2e2dfa3251a6a584 262 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 34 213 1.8E-50 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal SMD11_RS13340 d85af77ac6d2fdfe2e2dfa3251a6a584 262 SMART SM01007 33 213 1.5E-60 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal SMD11_RS13340 d85af77ac6d2fdfe2e2dfa3251a6a584 262 Gene3D G3DSA:3.40.225.10 27 238 1.0E-67 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal SMD11_RS13340 d85af77ac6d2fdfe2e2dfa3251a6a584 262 SUPERFAMILY SSF53639 26 244 9.81E-70 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal SMD11_RS25930 f6b6531b21a56f8d12c5cdfeaa4ac65e 138 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 5 92 29.141 T 06-07-2017 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMD11_RS25930 f6b6531b21a56f8d12c5cdfeaa4ac65e 138 Pfam PF00741 Gas vesicle protein 18 55 1.1E-12 T 06-07-2017 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMD11_RS25930 f6b6531b21a56f8d12c5cdfeaa4ac65e 138 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 18 32 - T 06-07-2017 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMD11_RS25930 f6b6531b21a56f8d12c5cdfeaa4ac65e 138 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 51 64 - T 06-07-2017 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMD11_RS06170 768cc9bee0061d29bb11761e2238a8b5 177 Pfam PF07275 Antirestriction protein (ArdA) 4 141 3.0E-28 T 06-07-2017 IPR009899 Antirestriction SMD11_RS08805 0f3fb6dda92ca66a71e956e2529b2510 956 Pfam PF02867 Ribonucleotide reductase, barrel domain 158 697 5.7E-147 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS08805 0f3fb6dda92ca66a71e956e2529b2510 956 Gene3D G3DSA:3.20.70.20 543 589 6.5E-100 T 06-07-2017 SMD11_RS08805 0f3fb6dda92ca66a71e956e2529b2510 956 Gene3D G3DSA:3.20.70.20 656 701 6.5E-100 T 06-07-2017 SMD11_RS08805 0f3fb6dda92ca66a71e956e2529b2510 956 Gene3D G3DSA:3.20.70.20 68 484 6.5E-100 T 06-07-2017 SMD11_RS08805 0f3fb6dda92ca66a71e956e2529b2510 956 PRINTS PR01183 Ribonucleotide reductase large chain signature 436 458 3.4E-16 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS08805 0f3fb6dda92ca66a71e956e2529b2510 956 PRINTS PR01183 Ribonucleotide reductase large chain signature 464 487 3.4E-16 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS08805 0f3fb6dda92ca66a71e956e2529b2510 956 PRINTS PR01183 Ribonucleotide reductase large chain signature 360 371 3.4E-16 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS08805 0f3fb6dda92ca66a71e956e2529b2510 956 PRINTS PR01183 Ribonucleotide reductase large chain signature 398 421 3.4E-16 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS08805 0f3fb6dda92ca66a71e956e2529b2510 956 PRINTS PR01183 Ribonucleotide reductase large chain signature 233 252 3.4E-16 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS08805 0f3fb6dda92ca66a71e956e2529b2510 956 PRINTS PR01183 Ribonucleotide reductase large chain signature 543 570 3.4E-16 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS08805 0f3fb6dda92ca66a71e956e2529b2510 956 SUPERFAMILY SSF51998 630 708 1.92E-131 T 06-07-2017 SMD11_RS08805 0f3fb6dda92ca66a71e956e2529b2510 956 SUPERFAMILY SSF51998 158 595 1.92E-131 T 06-07-2017 SMD11_RS08805 0f3fb6dda92ca66a71e956e2529b2510 956 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 92 707 1.5E-188 T 06-07-2017 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD11_RS08805 0f3fb6dda92ca66a71e956e2529b2510 956 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 54 137 2.3E-19 T 06-07-2017 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SMD11_RS25595 b7baf1af5febfa4c734b976e5025645f 410 SUPERFAMILY SSF56784 192 398 2.4E-48 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS25595 b7baf1af5febfa4c734b976e5025645f 410 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 193 363 1.0E-29 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 SMD11_RS25595 b7baf1af5febfa4c734b976e5025645f 410 Pfam PF12710 haloacid dehalogenase-like hydrolase 194 361 3.6E-25 T 06-07-2017 SMD11_RS25595 b7baf1af5febfa4c734b976e5025645f 410 SUPERFAMILY SSF55021 20 92 6.87E-8 T 06-07-2017 SMD11_RS25595 b7baf1af5febfa4c734b976e5025645f 410 Pfam PF13740 ACT domain 19 94 3.1E-16 T 06-07-2017 SMD11_RS25595 b7baf1af5febfa4c734b976e5025645f 410 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 185 396 1.1E-76 T 06-07-2017 SMD11_RS25595 b7baf1af5febfa4c734b976e5025645f 410 Gene3D G3DSA:1.10.150.210 203 254 3.0E-25 T 06-07-2017 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 SMD11_RS25595 b7baf1af5febfa4c734b976e5025645f 410 Gene3D G3DSA:3.40.50.1000 255 383 8.6E-46 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS25595 b7baf1af5febfa4c734b976e5025645f 410 Gene3D G3DSA:3.30.70.260 19 95 3.2E-14 T 06-07-2017 SMD11_RS29785 3640939889411857ccef52db94be0ee0 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 318 4.8E-46 T 06-07-2017 SMD11_RS29785 3640939889411857ccef52db94be0ee0 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 267 282 4.8E-46 T 06-07-2017 SMD11_RS29785 3640939889411857ccef52db94be0ee0 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 334 4.8E-46 T 06-07-2017 SMD11_RS29785 3640939889411857ccef52db94be0ee0 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 298 4.8E-46 T 06-07-2017 SMD11_RS29785 3640939889411857ccef52db94be0ee0 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 4.8E-46 T 06-07-2017 SMD11_RS29785 3640939889411857ccef52db94be0ee0 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 4.8E-46 T 06-07-2017 SMD11_RS29785 3640939889411857ccef52db94be0ee0 490 Pfam PF01494 FAD binding domain 3 332 1.1E-91 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS29785 3640939889411857ccef52db94be0ee0 490 SUPERFAMILY SSF51905 254 349 6.17E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29785 3640939889411857ccef52db94be0ee0 490 SUPERFAMILY SSF51905 5 165 6.17E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29785 3640939889411857ccef52db94be0ee0 490 Gene3D G3DSA:3.30.9.10 156 260 3.0E-9 T 06-07-2017 SMD11_RS29785 3640939889411857ccef52db94be0ee0 490 Gene3D G3DSA:3.30.9.10 315 335 3.0E-9 T 06-07-2017 SMD11_RS29785 3640939889411857ccef52db94be0ee0 490 Gene3D G3DSA:3.50.50.60 265 305 5.8E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29785 3640939889411857ccef52db94be0ee0 490 Gene3D G3DSA:3.50.50.60 3 155 5.8E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS08565 710d854fa154a2cb188a75645d720d28 387 Hamap MF_00323 Ferrochelatase [hemH]. 21 342 29.431 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 SMD11_RS08565 710d854fa154a2cb188a75645d720d28 387 Gene3D G3DSA:3.40.50.1400 20 176 4.1E-38 T 06-07-2017 SMD11_RS08565 710d854fa154a2cb188a75645d720d28 387 Gene3D G3DSA:3.40.50.1400 177 323 1.1E-45 T 06-07-2017 SMD11_RS08565 710d854fa154a2cb188a75645d720d28 387 Pfam PF00762 Ferrochelatase 23 341 2.0E-91 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 SMD11_RS08565 710d854fa154a2cb188a75645d720d28 387 SUPERFAMILY SSF53800 21 351 5.72E-79 T 06-07-2017 SMD11_RS32575 58792c5d23cd06afe739dbca8d77e802 345 Pfam PF13480 Acetyltransferase (GNAT) domain 184 324 2.9E-9 T 06-07-2017 SMD11_RS32575 58792c5d23cd06afe739dbca8d77e802 345 SUPERFAMILY SSF55729 173 334 6.36E-15 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS32575 58792c5d23cd06afe739dbca8d77e802 345 Gene3D G3DSA:3.40.630.30 164 319 7.5E-6 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS33965 c7d2d99c56cf2b91d44a438381ffed52 589 Pfam PF00652 Ricin-type beta-trefoil lectin domain 454 583 3.3E-10 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS33965 c7d2d99c56cf2b91d44a438381ffed52 589 Gene3D G3DSA:2.80.10.50 452 585 1.3E-11 T 06-07-2017 SMD11_RS33965 c7d2d99c56cf2b91d44a438381ffed52 589 SUPERFAMILY SSF50370 451 585 3.69E-15 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS33965 c7d2d99c56cf2b91d44a438381ffed52 589 SMART SM00458 452 586 8.1E-4 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS21505 b080871816b3bc6eddb43ce77dd13146 259 Pfam PF13242 HAD-hyrolase-like 182 255 4.6E-21 T 06-07-2017 SMD11_RS21505 b080871816b3bc6eddb43ce77dd13146 259 Pfam PF13344 Haloacid dehalogenase-like hydrolase 10 109 2.2E-25 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA SMD11_RS21505 b080871816b3bc6eddb43ce77dd13146 259 Gene3D G3DSA:3.40.50.1000 182 258 1.4E-39 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS21505 b080871816b3bc6eddb43ce77dd13146 259 Gene3D G3DSA:3.40.50.1000 6 83 1.4E-39 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS21505 b080871816b3bc6eddb43ce77dd13146 259 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 11 231 4.9E-47 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA SMD11_RS21505 b080871816b3bc6eddb43ce77dd13146 259 Gene3D G3DSA:3.40.50.10410 88 181 2.1E-34 T 06-07-2017 IPR023215 Nitrophenylphosphatase-like domain SMD11_RS21505 b080871816b3bc6eddb43ce77dd13146 259 PIRSF PIRSF000915 3 259 6.1E-54 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA SMD11_RS21505 b080871816b3bc6eddb43ce77dd13146 259 SUPERFAMILY SSF56784 7 257 1.16E-67 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS17490 10a1c2ded2f76ae8e881ab0f7b95d1a4 855 Pfam PF12846 AAA-like domain 471 824 2.3E-26 T 06-07-2017 SMD11_RS17490 10a1c2ded2f76ae8e881ab0f7b95d1a4 855 SUPERFAMILY SSF52540 427 777 9.63E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17490 10a1c2ded2f76ae8e881ab0f7b95d1a4 855 Gene3D G3DSA:3.40.50.300 476 542 9.5E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17490 10a1c2ded2f76ae8e881ab0f7b95d1a4 855 Gene3D G3DSA:3.40.50.300 641 772 9.5E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16395 7e5bb8d923fcbc06c64761c31ec6f289 415 Gene3D G3DSA:3.40.47.10 303 380 8.1E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS16395 7e5bb8d923fcbc06c64761c31ec6f289 415 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 86 265 5.9E-14 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS16395 7e5bb8d923fcbc06c64761c31ec6f289 415 SUPERFAMILY SSF53901 251 412 1.15E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS16395 7e5bb8d923fcbc06c64761c31ec6f289 415 SUPERFAMILY SSF53901 39 265 2.77E-24 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS16395 7e5bb8d923fcbc06c64761c31ec6f289 415 Gene3D G3DSA:3.40.47.10 88 265 5.3E-20 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS30665 cb0b85002da04bec032fe9c67783e15e 254 Gene3D G3DSA:3.40.50.720 2 250 5.0E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30665 cb0b85002da04bec032fe9c67783e15e 254 SUPERFAMILY SSF51735 6 250 4.15E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30665 cb0b85002da04bec032fe9c67783e15e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 8.6E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30665 cb0b85002da04bec032fe9c67783e15e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 8.6E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30665 cb0b85002da04bec032fe9c67783e15e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 8.6E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30665 cb0b85002da04bec032fe9c67783e15e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.6E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30665 cb0b85002da04bec032fe9c67783e15e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 8.6E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30665 cb0b85002da04bec032fe9c67783e15e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 8.6E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30665 cb0b85002da04bec032fe9c67783e15e 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30665 cb0b85002da04bec032fe9c67783e15e 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30665 cb0b85002da04bec032fe9c67783e15e 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30665 cb0b85002da04bec032fe9c67783e15e 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 187 0.0088 T 06-07-2017 SMD11_RS30665 cb0b85002da04bec032fe9c67783e15e 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 248 2.8E-56 T 06-07-2017 SMD11_RS21450 d85a594a713186e1850a40965c9314cf 171 SUPERFAMILY SSF143744 31 169 2.35E-24 T 06-07-2017 SMD11_RS21450 d85a594a713186e1850a40965c9314cf 171 Hamap MF_00761 UPF0303 protein . 17 171 31.278 T 06-07-2017 IPR010371 Uncharacterised protein family UPF0303 SMD11_RS21450 d85a594a713186e1850a40965c9314cf 171 Pfam PF03928 Haem-degrading 39 166 4.8E-30 T 06-07-2017 IPR005624 Haem-degrading SMD11_RS21450 d85a594a713186e1850a40965c9314cf 171 PIRSF PIRSF008757 17 171 2.8E-57 T 06-07-2017 IPR010371 Uncharacterised protein family UPF0303 SMD11_RS09005 3ebec471435d2b9a33437f7a8de75fab 495 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 5 483 60.279 T 06-07-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 SMD11_RS09005 3ebec471435d2b9a33437f7a8de75fab 495 SUPERFAMILY SSF102114 175 411 9.81E-43 T 06-07-2017 SMD11_RS09005 3ebec471435d2b9a33437f7a8de75fab 495 Gene3D G3DSA:2.40.50.140 422 484 2.1E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS09005 3ebec471435d2b9a33437f7a8de75fab 495 Pfam PF04055 Radical SAM superfamily 195 365 6.0E-18 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS09005 3ebec471435d2b9a33437f7a8de75fab 495 SMART SM00729 189 407 8.6E-38 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD11_RS09005 3ebec471435d2b9a33437f7a8de75fab 495 Pfam PF00919 Uncharacterized protein family UPF0004 7 105 2.7E-31 T 06-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 SMD11_RS09005 3ebec471435d2b9a33437f7a8de75fab 495 Gene3D G3DSA:3.80.30.20 189 418 5.1E-59 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe SMD11_RS09005 3ebec471435d2b9a33437f7a8de75fab 495 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 187 480 5.2E-79 T 06-07-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 SMD11_RS09005 3ebec471435d2b9a33437f7a8de75fab 495 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 7 480 8.5E-118 T 06-07-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 SMD11_RS09005 3ebec471435d2b9a33437f7a8de75fab 495 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 193 213 - T 06-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 SMD11_RS31585 c15e76e8de2ec2cbd089996e5f2619bb 308 Pfam PF02126 Phosphotriesterase family 24 303 1.4E-34 T 06-07-2017 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 SMD11_RS31585 c15e76e8de2ec2cbd089996e5f2619bb 308 Gene3D G3DSA:3.20.20.140 13 305 2.9E-74 T 06-07-2017 SMD11_RS31585 c15e76e8de2ec2cbd089996e5f2619bb 308 SUPERFAMILY SSF51556 13 305 1.64E-57 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS31585 c15e76e8de2ec2cbd089996e5f2619bb 308 PIRSF PIRSF016839 11 308 2.9E-81 T 06-07-2017 SMD11_RS30505 db686a37250e23507c0f8b2fcccda4d6 286 Pfam PF01457 Leishmanolysin 107 240 1.1E-12 T 06-07-2017 IPR001577 Peptidase M8, leishmanolysin GO:0004222|GO:0006508|GO:0007155|GO:0016020 SMD11_RS30505 db686a37250e23507c0f8b2fcccda4d6 286 Gene3D G3DSA:3.90.132.10 159 242 2.6E-10 T 06-07-2017 SMD11_RS30505 db686a37250e23507c0f8b2fcccda4d6 286 SUPERFAMILY SSF55486 106 243 3.66E-30 T 06-07-2017 SMD11_RS30505 db686a37250e23507c0f8b2fcccda4d6 286 Gene3D G3DSA:3.40.390.10 24 142 4.4E-8 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD11_RS30505 db686a37250e23507c0f8b2fcccda4d6 286 SUPERFAMILY SSF55486 27 143 1.02E-7 T 06-07-2017 SMD11_RS00240 53aacc030b6da463153c0f6c6dfca19a 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 2.7E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00240 53aacc030b6da463153c0f6c6dfca19a 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 2.7E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00240 53aacc030b6da463153c0f6c6dfca19a 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 51 2.2E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS00240 53aacc030b6da463153c0f6c6dfca19a 192 Pfam PF13977 Bacterial transcriptional repressor 76 188 7.8E-16 T 06-07-2017 SMD11_RS00240 53aacc030b6da463153c0f6c6dfca19a 192 SUPERFAMILY SSF46689 3 78 2.67E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS00240 53aacc030b6da463153c0f6c6dfca19a 192 Gene3D G3DSA:1.10.357.10 3 183 1.1E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS00240 53aacc030b6da463153c0f6c6dfca19a 192 SUPERFAMILY SSF48498 75 185 2.09E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS16575 2fc48d8b9b48ea5c20e7c1cb03a7713e 368 Pfam PF00149 Calcineurin-like phosphoesterase 98 311 3.7E-8 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 SMD11_RS16575 2fc48d8b9b48ea5c20e7c1cb03a7713e 368 SUPERFAMILY SSF56300 82 184 2.8E-33 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS16575 2fc48d8b9b48ea5c20e7c1cb03a7713e 368 SUPERFAMILY SSF56300 216 355 2.8E-33 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS16575 2fc48d8b9b48ea5c20e7c1cb03a7713e 368 PRINTS PR00114 Serine/threonine phosphatase family signature 97 124 8.6E-5 T 06-07-2017 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04660+3.1.3.16 SMD11_RS16575 2fc48d8b9b48ea5c20e7c1cb03a7713e 368 PRINTS PR00114 Serine/threonine phosphatase family signature 134 161 8.6E-5 T 06-07-2017 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04660+3.1.3.16 SMD11_RS16575 2fc48d8b9b48ea5c20e7c1cb03a7713e 368 Gene3D G3DSA:3.60.21.10 86 365 1.1E-33 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS27830 960c19e074744ef4985eaf4e01aa2f26 227 SUPERFAMILY SSF53474 29 162 6.6E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS27830 960c19e074744ef4985eaf4e01aa2f26 227 Pfam PF01674 Lipase (class 2) 33 187 5.3E-15 T 06-07-2017 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 SMD11_RS27830 960c19e074744ef4985eaf4e01aa2f26 227 Gene3D G3DSA:3.40.50.1820 27 222 1.7E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS00760 0b12638944c8d101a8328ddd2e6ac7b3 270 Gene3D G3DSA:3.40.50.150 1 220 1.0E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS00760 0b12638944c8d101a8328ddd2e6ac7b3 270 Pfam PF13649 Methyltransferase domain 42 144 4.6E-16 T 06-07-2017 SMD11_RS00760 0b12638944c8d101a8328ddd2e6ac7b3 270 SUPERFAMILY SSF53335 27 221 8.06E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS11830 2dcdb1d4328eeb20a8350b465139f163 258 Gene3D G3DSA:1.10.10.10 167 230 4.6E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11830 2dcdb1d4328eeb20a8350b465139f163 258 Pfam PF04542 Sigma-70 region 2 75 140 6.0E-21 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11830 2dcdb1d4328eeb20a8350b465139f163 258 Pfam PF08281 Sigma-70, region 4 173 224 7.5E-17 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11830 2dcdb1d4328eeb20a8350b465139f163 258 SUPERFAMILY SSF88946 70 151 8.44E-24 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11830 2dcdb1d4328eeb20a8350b465139f163 258 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 71 228 4.5E-33 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11830 2dcdb1d4328eeb20a8350b465139f163 258 SUPERFAMILY SSF88659 169 229 2.62E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11830 2dcdb1d4328eeb20a8350b465139f163 258 Gene3D G3DSA:1.10.1740.10 70 162 3.0E-26 T 06-07-2017 SMD11_RS27915 951357f72f072151a98f07253179a94f 666 Pfam PF11308 Glycosyl hydrolases related to GH101 family, GH129 299 618 7.2E-95 T 06-07-2017 IPR021459 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 SMD11_RS14740 5d2dcb0ac2ca3873a1b5b0e53794db4f 193 Gene3D G3DSA:1.20.144.10 2 170 5.6E-32 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS14740 5d2dcb0ac2ca3873a1b5b0e53794db4f 193 SMART SM00014 54 168 8.1E-17 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS14740 5d2dcb0ac2ca3873a1b5b0e53794db4f 193 Pfam PF01569 PAP2 superfamily 61 170 6.7E-18 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS14740 5d2dcb0ac2ca3873a1b5b0e53794db4f 193 SUPERFAMILY SSF48317 2 170 1.57E-33 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS05195 e51c9377c67b75867028fca34256c3b3 136 Gene3D G3DSA:1.10.260.40 2 57 1.1E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS05195 e51c9377c67b75867028fca34256c3b3 136 SUPERFAMILY SSF47413 2 57 7.6E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS31345 001584445985d89f0466165f4162348f 209 Gene3D G3DSA:2.20.25.10 160 186 3.7E-4 T 06-07-2017 SMD11_RS31345 001584445985d89f0466165f4162348f 209 Pfam PF01385 Probable transposase 2 100 2.0E-19 T 06-07-2017 IPR001959 Probable transposase, IS891/IS1136/IS1341 SMD11_RS31345 001584445985d89f0466165f4162348f 209 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 68 160 1.4E-6 T 06-07-2017 IPR010095 Transposase IS605, OrfB, C-terminal SMD11_RS31345 001584445985d89f0466165f4162348f 209 Pfam PF07282 Putative transposase DNA-binding domain 133 201 1.9E-22 T 06-07-2017 IPR010095 Transposase IS605, OrfB, C-terminal SMD11_RS30815 cbfd909bd4d5f7de12c0177fb69539e5 195 SUPERFAMILY SSF46689 5 75 3.45E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS30815 cbfd909bd4d5f7de12c0177fb69539e5 195 Gene3D G3DSA:1.10.10.60 14 56 5.7E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS30815 cbfd909bd4d5f7de12c0177fb69539e5 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 58 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD11_RS30815 cbfd909bd4d5f7de12c0177fb69539e5 195 Gene3D G3DSA:1.10.357.10 57 191 1.3E-40 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS30815 cbfd909bd4d5f7de12c0177fb69539e5 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 5.4E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS30815 cbfd909bd4d5f7de12c0177fb69539e5 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS30815 cbfd909bd4d5f7de12c0177fb69539e5 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS03870 b6ba9af3d0f7708f8725ffe09b5ee1e4 249 SUPERFAMILY SSF88713 57 244 8.4E-56 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS03870 b6ba9af3d0f7708f8725ffe09b5ee1e4 249 Gene3D G3DSA:3.20.20.370 53 244 1.5E-58 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS03870 b6ba9af3d0f7708f8725ffe09b5ee1e4 249 Pfam PF01522 Polysaccharide deacetylase 60 181 1.8E-28 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS33160 4c487863c8808f107829234aebeaa1b2 650 Pfam PF04865 Baseplate J-like protein 398 569 4.5E-15 T 06-07-2017 IPR006949 Baseplate protein J-like SMD11_RS33160 4c487863c8808f107829234aebeaa1b2 650 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 7 609 3.8E-161 T 06-07-2017 IPR011749 Conserved hypothetical protein CHP02243 SMD11_RS21455 ad8e9cb42d082f8e66322f5361a18aa4 377 SUPERFAMILY SSF55347 146 345 1.8E-26 T 06-07-2017 SMD11_RS21455 ad8e9cb42d082f8e66322f5361a18aa4 377 Gene3D G3DSA:3.30.360.10 147 366 1.7E-38 T 06-07-2017 SMD11_RS21455 ad8e9cb42d082f8e66322f5361a18aa4 377 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 153 232 4.8E-12 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD11_RS21455 ad8e9cb42d082f8e66322f5361a18aa4 377 Gene3D G3DSA:3.40.50.720 16 146 4.5E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS21455 ad8e9cb42d082f8e66322f5361a18aa4 377 SUPERFAMILY SSF51735 14 174 9.21E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS21455 ad8e9cb42d082f8e66322f5361a18aa4 377 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 18 136 6.9E-23 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD11_RS30425 041d8269c4b10e89664cd78b08b4b228 235 SUPERFAMILY SSF53901 71 155 2.12E-21 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS30425 041d8269c4b10e89664cd78b08b4b228 235 Gene3D G3DSA:3.40.47.10 88 158 3.1E-22 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS30425 041d8269c4b10e89664cd78b08b4b228 235 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 80 152 1.7E-18 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS08370 c2814b11402d60e7eac0bc52953b4abc 469 Pfam PF07690 Major Facilitator Superfamily 98 354 5.2E-10 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS08370 c2814b11402d60e7eac0bc52953b4abc 469 Gene3D G3DSA:1.20.1250.20 98 214 3.5E-5 T 06-07-2017 SMD11_RS08370 c2814b11402d60e7eac0bc52953b4abc 469 SUPERFAMILY SSF103473 14 444 1.44E-12 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS27475 e60a6bb02eb93ebc0c3c65138659212a 482 Pfam PF00860 Permease family 36 405 9.4E-69 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD11_RS26805 aa73f62352a94819960a7391dcf742fa 383 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 382 2.4E-103 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD11_RS26805 aa73f62352a94819960a7391dcf742fa 383 SUPERFAMILY SSF56266 7 379 2.09E-127 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD11_RS26805 aa73f62352a94819960a7391dcf742fa 383 Gene3D G3DSA:3.60.70.12 2 259 6.9E-95 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD11_RS26805 aa73f62352a94819960a7391dcf742fa 383 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 383 132.993 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD11_RS26805 aa73f62352a94819960a7391dcf742fa 383 Pfam PF01960 ArgJ family 11 383 1.3E-126 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD11_RS26805 aa73f62352a94819960a7391dcf742fa 383 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 18 381 3.0E-171 T 06-07-2017 SMD11_RS09070 6d23812e9fecae778e780de69f455f25 299 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 14 290 1.4E-89 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS09070 6d23812e9fecae778e780de69f455f25 299 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 10 294 59.222 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS09070 6d23812e9fecae778e780de69f455f25 299 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 142 172 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS09070 6d23812e9fecae778e780de69f455f25 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 112 128 4.4E-31 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS09070 6d23812e9fecae778e780de69f455f25 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 4.4E-31 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS09070 6d23812e9fecae778e780de69f455f25 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 44 65 4.4E-31 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS09070 6d23812e9fecae778e780de69f455f25 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 80 98 4.4E-31 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS09070 6d23812e9fecae778e780de69f455f25 299 SUPERFAMILY SSF51569 7 293 6.7E-98 T 06-07-2017 SMD11_RS09070 6d23812e9fecae778e780de69f455f25 299 Pfam PF00701 Dihydrodipicolinate synthetase family 11 294 3.3E-86 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS09070 6d23812e9fecae778e780de69f455f25 299 SMART SM01130 10 295 3.8E-125 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS09070 6d23812e9fecae778e780de69f455f25 299 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 47 64 - T 06-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS09070 6d23812e9fecae778e780de69f455f25 299 Gene3D G3DSA:3.20.20.70 9 294 3.7E-110 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS09070 6d23812e9fecae778e780de69f455f25 299 PIRSF PIRSF001365 7 298 3.2E-84 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS21220 064548a5145831c51a66a57c3d50ebca 140 Pfam PF14464 Prokaryotic homologs of the JAB domain 6 111 3.4E-28 T 06-07-2017 IPR028090 JAB domain, prokaryotic SMD11_RS21220 064548a5145831c51a66a57c3d50ebca 140 SMART SM00232 1 134 6.4E-28 T 06-07-2017 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 SMD11_RS21220 064548a5145831c51a66a57c3d50ebca 140 Gene3D G3DSA:3.40.140.10 1 136 2.3E-35 T 06-07-2017 SMD11_RS21220 064548a5145831c51a66a57c3d50ebca 140 SUPERFAMILY SSF102712 1 132 7.45E-28 T 06-07-2017 SMD11_RS07570 ae54c3decdefbb6d75d88fb47dc1382a 257 Gene3D G3DSA:1.10.3720.10 2 245 3.6E-60 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS07570 ae54c3decdefbb6d75d88fb47dc1382a 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 65 251 2.2E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS07570 ae54c3decdefbb6d75d88fb47dc1382a 257 SUPERFAMILY SSF161098 2 257 6.28E-66 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS10305 a61978bee761784c8b316e23854dbe20 285 SUPERFAMILY SSF89392 58 262 3.57E-10 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX SMD11_RS07180 7726712c40ed2b9f70979c2b98fc06bb 425 Gene3D G3DSA:1.10.10.10 327 379 8.0E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07180 7726712c40ed2b9f70979c2b98fc06bb 425 Gene3D G3DSA:3.30.450.40 73 208 1.8E-4 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS07180 7726712c40ed2b9f70979c2b98fc06bb 425 SUPERFAMILY SSF55781 76 213 5.05E-6 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS07180 7726712c40ed2b9f70979c2b98fc06bb 425 Pfam PF01590 GAF domain 95 210 5.5E-12 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS11100 bfc568adbf5ff45e8d83cbb65ef5ea32 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 282 2.0E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11100 bfc568adbf5ff45e8d83cbb65ef5ea32 316 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 69 177 3.2E-18 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMD11_RS11100 bfc568adbf5ff45e8d83cbb65ef5ea32 316 Gene3D G3DSA:1.10.3720.10 67 283 2.6E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11100 bfc568adbf5ff45e8d83cbb65ef5ea32 316 SUPERFAMILY SSF161098 68 269 8.24E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS23980 77f2a17fe7bb24b254e00c416f4ba108 292 SUPERFAMILY SSF56327 152 282 4.17E-16 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMD11_RS23980 77f2a17fe7bb24b254e00c416f4ba108 292 Gene3D G3DSA:3.90.110.10 149 270 2.8E-15 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SMD11_RS23980 77f2a17fe7bb24b254e00c416f4ba108 292 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 9 143 1.1E-12 T 06-07-2017 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 SMD11_RS23980 77f2a17fe7bb24b254e00c416f4ba108 292 SUPERFAMILY SSF51735 8 146 4.77E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS23980 77f2a17fe7bb24b254e00c416f4ba108 292 PIRSF PIRSF000102 7 291 6.1E-41 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SMD11_RS23980 77f2a17fe7bb24b254e00c416f4ba108 292 Gene3D G3DSA:3.40.50.720 9 148 7.5E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS23980 77f2a17fe7bb24b254e00c416f4ba108 292 PRINTS PR00086 L-lactate dehydrogenase signature 144 162 8.8E-20 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SMD11_RS23980 77f2a17fe7bb24b254e00c416f4ba108 292 PRINTS PR00086 L-lactate dehydrogenase signature 8 32 8.8E-20 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SMD11_RS23980 77f2a17fe7bb24b254e00c416f4ba108 292 PRINTS PR00086 L-lactate dehydrogenase signature 122 142 8.8E-20 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SMD11_RS23980 77f2a17fe7bb24b254e00c416f4ba108 292 PRINTS PR00086 L-lactate dehydrogenase signature 174 187 8.8E-20 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SMD11_RS08850 4d8b319b1a5e0f80b751433b97ed54b2 490 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 168 183 2.6E-9 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS08850 4d8b319b1a5e0f80b751433b97ed54b2 490 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 323 338 2.6E-9 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS08850 4d8b319b1a5e0f80b751433b97ed54b2 490 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 342 354 2.6E-9 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS08850 4d8b319b1a5e0f80b751433b97ed54b2 490 Gene3D G3DSA:1.10.390.10 337 477 8.0E-20 T 06-07-2017 SMD11_RS08850 4d8b319b1a5e0f80b751433b97ed54b2 490 SUPERFAMILY SSF55486 240 476 1.26E-50 T 06-07-2017 SMD11_RS08850 4d8b319b1a5e0f80b751433b97ed54b2 490 SUPERFAMILY SSF63737 45 231 1.7E-31 T 06-07-2017 SMD11_RS08850 4d8b319b1a5e0f80b751433b97ed54b2 490 Pfam PF01433 Peptidase family M1 61 377 2.4E-29 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS04620 b83145a50fe34ec7f3c2e1e15fdeb22a 98 SMART SM01294 21 87 6.7E-4 T 06-07-2017 SMD11_RS04620 b83145a50fe34ec7f3c2e1e15fdeb22a 98 Gene3D G3DSA:1.10.1200.10 17 91 1.6E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS04620 b83145a50fe34ec7f3c2e1e15fdeb22a 98 SUPERFAMILY SSF47336 15 91 4.06E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS04620 b83145a50fe34ec7f3c2e1e15fdeb22a 98 SMART SM00823 Phosphopantetheine attachment site 20 91 6.3E-12 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS04620 b83145a50fe34ec7f3c2e1e15fdeb22a 98 Pfam PF00550 Phosphopantetheine attachment site 21 87 3.0E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS18090 c8da801e836368f03cac092bc66b217c 407 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 37 228 9.9E-32 T 06-07-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMD11_RS18090 c8da801e836368f03cac092bc66b217c 407 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 350 368 - T 06-07-2017 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 SMD11_RS18090 c8da801e836368f03cac092bc66b217c 407 SUPERFAMILY SSF53335 34 279 1.07E-63 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS18090 c8da801e836368f03cac092bc66b217c 407 SUPERFAMILY SSF53335 311 371 1.07E-63 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS18090 c8da801e836368f03cac092bc66b217c 407 Gene3D G3DSA:3.40.50.150 29 242 6.1E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS18090 c8da801e836368f03cac092bc66b217c 407 Pfam PF00145 C-5 cytosine-specific DNA methylase 35 368 1.0E-51 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS18090 c8da801e836368f03cac092bc66b217c 407 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 113 125 - T 06-07-2017 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 SMD11_RS18090 c8da801e836368f03cac092bc66b217c 407 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 198 211 6.1E-11 T 06-07-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMD11_RS18090 c8da801e836368f03cac092bc66b217c 407 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 35 51 6.1E-11 T 06-07-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMD11_RS18090 c8da801e836368f03cac092bc66b217c 407 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 151 165 6.1E-11 T 06-07-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 SMD11_RS10945 eaa0e6e846852af60c2b4cbc80d5dab4 439 SUPERFAMILY SSF51905 4 163 1.18E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS10945 eaa0e6e846852af60c2b4cbc80d5dab4 439 SUPERFAMILY SSF51905 288 392 1.18E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS10945 eaa0e6e846852af60c2b4cbc80d5dab4 439 Gene3D G3DSA:3.40.50.720 112 153 5.4E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10945 eaa0e6e846852af60c2b4cbc80d5dab4 439 Gene3D G3DSA:3.40.50.720 3 56 5.4E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10945 eaa0e6e846852af60c2b4cbc80d5dab4 439 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 1.0E-6 T 06-07-2017 SMD11_RS10945 eaa0e6e846852af60c2b4cbc80d5dab4 439 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.0E-6 T 06-07-2017 SMD11_RS30160 17b7ae85f4dd007b1174afc22555642b 292 SUPERFAMILY SSF51735 235 287 5.13E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30160 17b7ae85f4dd007b1174afc22555642b 292 SUPERFAMILY SSF51735 10 203 5.13E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30160 17b7ae85f4dd007b1174afc22555642b 292 Gene3D G3DSA:3.40.50.720 12 271 6.4E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30160 17b7ae85f4dd007b1174afc22555642b 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 9.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30160 17b7ae85f4dd007b1174afc22555642b 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 9.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30160 17b7ae85f4dd007b1174afc22555642b 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 9.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30160 17b7ae85f4dd007b1174afc22555642b 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 9.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30160 17b7ae85f4dd007b1174afc22555642b 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 9.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30160 17b7ae85f4dd007b1174afc22555642b 292 Pfam PF00106 short chain dehydrogenase 14 203 1.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30160 17b7ae85f4dd007b1174afc22555642b 292 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 196 0.0045 T 06-07-2017 SMD11_RS04310 174b4346ea858ed716fe7a7ea788331e 208 Pfam PF02570 Precorrin-8X methylmutase 11 205 2.1E-74 T 06-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 SMD11_RS04310 174b4346ea858ed716fe7a7ea788331e 208 SUPERFAMILY SSF63965 3 205 1.31E-74 T 06-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 SMD11_RS04310 174b4346ea858ed716fe7a7ea788331e 208 Gene3D G3DSA:3.40.50.10230 3 204 2.9E-81 T 06-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 SMD11_RS10120 069736fb83815d4c22513654095a7c1d 502 SUPERFAMILY SSF55931 18 320 7.19E-109 T 06-07-2017 SMD11_RS10120 069736fb83815d4c22513654095a7c1d 502 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 15 498 2.0E-140 T 06-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 SMD11_RS10120 069736fb83815d4c22513654095a7c1d 502 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 164 178 - T 06-07-2017 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 SMD11_RS10120 069736fb83815d4c22513654095a7c1d 502 SUPERFAMILY SSF89095 352 498 2.62E-24 T 06-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 SMD11_RS10120 069736fb83815d4c22513654095a7c1d 502 Pfam PF02934 GatB/GatE catalytic domain 19 313 4.1E-101 T 06-07-2017 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 SMD11_RS10120 069736fb83815d4c22513654095a7c1d 502 Gene3D G3DSA:1.10.10.410 443 498 7.5E-5 T 06-07-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal SMD11_RS10120 069736fb83815d4c22513654095a7c1d 502 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 15 499 35.845 T 06-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 SMD11_RS10120 069736fb83815d4c22513654095a7c1d 502 Pfam PF02637 GatB domain 353 498 1.3E-39 T 06-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 SMD11_RS10120 069736fb83815d4c22513654095a7c1d 502 SMART SM00845 351 498 2.4E-56 T 06-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 SMD11_RS23805 b989c0516152f9cf2060d0a8798aaabd 240 Gene3D G3DSA:1.10.357.10 100 236 1.4E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS23805 b989c0516152f9cf2060d0a8798aaabd 240 Gene3D G3DSA:1.10.10.60 50 97 1.2E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS23805 b989c0516152f9cf2060d0a8798aaabd 240 Pfam PF16859 Bacterial transcriptional repressor C-terminal 118 230 2.3E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS23805 b989c0516152f9cf2060d0a8798aaabd 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 76 106 5.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS23805 b989c0516152f9cf2060d0a8798aaabd 240 SUPERFAMILY SSF46689 52 111 1.3E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS23805 b989c0516152f9cf2060d0a8798aaabd 240 SUPERFAMILY SSF48498 121 236 5.56E-25 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS26765 65d84fab604fd386bfb7bb5e8dfcb0be 421 Pfam PF02638 Glycosyl hydrolase-like 10 49 361 4.1E-85 T 06-07-2017 IPR003790 Glycosyl hydrolase-like 10 SMD11_RS26765 65d84fab604fd386bfb7bb5e8dfcb0be 421 SUPERFAMILY SSF51445 95 338 2.89E-21 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS06770 5c919c3fa9815bfb5850bdc370a1af63 158 SUPERFAMILY SSF50475 5 156 2.06E-45 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS06770 5c919c3fa9815bfb5850bdc370a1af63 158 Pfam PF01613 Flavin reductase like domain 12 156 1.1E-36 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS06770 5c919c3fa9815bfb5850bdc370a1af63 158 Gene3D G3DSA:2.30.110.10 5 157 2.3E-48 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS06770 5c919c3fa9815bfb5850bdc370a1af63 158 SMART SM00903 12 155 3.9E-53 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS11605 8d6fd97545328dd5d12beb587b5cd673 1251 Pfam PF12705 PD-(D/E)XK nuclease superfamily 998 1240 1.1E-34 T 06-07-2017 SMD11_RS11605 8d6fd97545328dd5d12beb587b5cd673 1251 Pfam PF00580 UvrD/REP helicase N-terminal domain 36 317 9.3E-51 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 SMD11_RS11605 8d6fd97545328dd5d12beb587b5cd673 1251 Gene3D G3DSA:3.40.50.300 220 319 4.8E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11605 8d6fd97545328dd5d12beb587b5cd673 1251 Gene3D G3DSA:3.40.50.300 33 174 4.8E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11605 8d6fd97545328dd5d12beb587b5cd673 1251 Gene3D G3DSA:3.40.50.300 332 453 4.5E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11605 8d6fd97545328dd5d12beb587b5cd673 1251 Gene3D G3DSA:3.40.50.300 796 900 4.5E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11605 8d6fd97545328dd5d12beb587b5cd673 1251 SUPERFAMILY SSF52540 677 896 5.7E-105 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11605 8d6fd97545328dd5d12beb587b5cd673 1251 SUPERFAMILY SSF52540 29 463 5.7E-105 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11605 8d6fd97545328dd5d12beb587b5cd673 1251 Pfam PF13361 UvrD-like helicase C-terminal domain 748 878 2.1E-19 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMD11_RS16230 d712e4ae5571a9d0ad8df28477325518 217 Pfam PF03992 Antibiotic biosynthesis monooxygenase 130 190 9.6E-6 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain SMD11_RS16230 d712e4ae5571a9d0ad8df28477325518 217 SUPERFAMILY SSF54909 121 191 2.29E-8 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS16230 d712e4ae5571a9d0ad8df28477325518 217 Gene3D G3DSA:3.30.70.900 115 214 1.9E-17 T 06-07-2017 SMD11_RS16230 d712e4ae5571a9d0ad8df28477325518 217 Gene3D G3DSA:3.30.70.900 16 98 6.3E-7 T 06-07-2017 SMD11_RS09955 32121ba0c48a1e3b375f842fc60dc4b2 368 SUPERFAMILY SSF56752 11 365 2.49E-116 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD11_RS09955 32121ba0c48a1e3b375f842fc60dc4b2 368 Gene3D G3DSA:3.20.10.10 180 353 3.7E-63 T 06-07-2017 SMD11_RS09955 32121ba0c48a1e3b375f842fc60dc4b2 368 Gene3D G3DSA:3.30.470.10 21 179 2.5E-72 T 06-07-2017 SMD11_RS09955 32121ba0c48a1e3b375f842fc60dc4b2 368 PIRSF PIRSF006468 5 368 1.8E-131 T 06-07-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 SMD11_RS09955 32121ba0c48a1e3b375f842fc60dc4b2 368 Pfam PF01063 Amino-transferase class IV 74 324 1.3E-28 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD11_RS09955 32121ba0c48a1e3b375f842fc60dc4b2 368 ProSitePatterns PS00770 Aminotransferases class-IV signature. 238 273 - T 06-07-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD11_RS09955 32121ba0c48a1e3b375f842fc60dc4b2 368 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 48 365 4.5E-130 T 06-07-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 SMD11_RS00895 76d2a21a8afa476d8a3138e7e17689ca 73 SMART SM00530 6 62 9.0E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS00895 76d2a21a8afa476d8a3138e7e17689ca 73 Gene3D G3DSA:1.10.260.40 1 69 4.6E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS00895 76d2a21a8afa476d8a3138e7e17689ca 73 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 68 3.2E-19 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS00895 76d2a21a8afa476d8a3138e7e17689ca 73 SUPERFAMILY SSF47413 2 67 3.85E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS09065 7603ec106318d8b80b923992ef084c8b 561 SMART SM00849 31 225 1.6E-21 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS09065 7603ec106318d8b80b923992ef084c8b 561 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 20 558 4.7E-152 T 06-07-2017 IPR004613 Ribonuclease J GO:0003723|GO:0046872 SMD11_RS09065 7603ec106318d8b80b923992ef084c8b 561 Hamap MF_01491 Ribonuclease J [rnj]. 14 561 41.199 T 06-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 SMD11_RS09065 7603ec106318d8b80b923992ef084c8b 561 PIRSF PIRSF004803 13 561 2.3E-207 T 06-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 SMD11_RS09065 7603ec106318d8b80b923992ef084c8b 561 SUPERFAMILY SSF56281 19 433 3.17E-95 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS09065 7603ec106318d8b80b923992ef084c8b 561 Pfam PF00753 Metallo-beta-lactamase superfamily 28 174 2.2E-14 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS09065 7603ec106318d8b80b923992ef084c8b 561 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 370 411 6.0E-10 T 06-07-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain SMD11_RS09065 7603ec106318d8b80b923992ef084c8b 561 Gene3D G3DSA:3.60.15.10 18 265 2.0E-77 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS20985 e3292a1ec98394b1cc0a80b1d093b51f 179 Pfam PF04545 Sigma-70, region 4 121 169 5.1E-12 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20985 e3292a1ec98394b1cc0a80b1d093b51f 179 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 44 76 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20985 e3292a1ec98394b1cc0a80b1d093b51f 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 170 2.1E-24 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20985 e3292a1ec98394b1cc0a80b1d093b51f 179 Pfam PF04542 Sigma-70 region 2 26 89 1.5E-17 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20985 e3292a1ec98394b1cc0a80b1d093b51f 179 Gene3D G3DSA:1.10.10.10 111 174 1.3E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20985 e3292a1ec98394b1cc0a80b1d093b51f 179 SUPERFAMILY SSF88946 12 105 5.89E-22 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20985 e3292a1ec98394b1cc0a80b1d093b51f 179 SUPERFAMILY SSF88659 108 171 1.87E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS20985 e3292a1ec98394b1cc0a80b1d093b51f 179 Gene3D G3DSA:1.10.1740.10 13 110 1.4E-22 T 06-07-2017 SMD11_RS21800 7cddc0d99ad110346bb4133a42a3d9b1 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 1.1E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS21800 7cddc0d99ad110346bb4133a42a3d9b1 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 1.1E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS21800 7cddc0d99ad110346bb4133a42a3d9b1 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 1.8E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS21800 7cddc0d99ad110346bb4133a42a3d9b1 207 SUPERFAMILY SSF48498 87 187 5.78E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS21800 7cddc0d99ad110346bb4133a42a3d9b1 207 SUPERFAMILY SSF46689 4 78 6.16E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS21800 7cddc0d99ad110346bb4133a42a3d9b1 207 Gene3D G3DSA:1.10.357.10 4 184 3.4E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS26390 99e5f3ebec7808c91b1290c67c217eea 284 Gene3D G3DSA:1.10.260.40 6 85 7.9E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS26390 99e5f3ebec7808c91b1290c67c217eea 284 SUPERFAMILY SSF47413 26 83 1.51E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS26390 99e5f3ebec7808c91b1290c67c217eea 284 SMART SM00530 14 86 2.3E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS26390 99e5f3ebec7808c91b1290c67c217eea 284 Pfam PF13560 Helix-turn-helix domain 10 89 3.9E-17 T 06-07-2017 SMD11_RS31340 386636e3bb522c2796d3dbd68bfd1bae 427 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 10 250 3.2E-104 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 SMD11_RS31340 386636e3bb522c2796d3dbd68bfd1bae 427 ProSitePatterns PS00161 Isocitrate lyase signature. 188 193 - T 06-07-2017 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 SMD11_RS31340 386636e3bb522c2796d3dbd68bfd1bae 427 SUPERFAMILY SSF51621 10 426 1.48E-156 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS31340 386636e3bb522c2796d3dbd68bfd1bae 427 Gene3D G3DSA:3.20.20.60 12 407 1.1E-162 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS31340 386636e3bb522c2796d3dbd68bfd1bae 427 PIRSF PIRSF001362 1 427 3.5E-235 T 06-07-2017 SMD11_RS31340 386636e3bb522c2796d3dbd68bfd1bae 427 Pfam PF00463 Isocitrate lyase family 15 250 4.8E-55 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 SMD11_RS31340 386636e3bb522c2796d3dbd68bfd1bae 427 Pfam PF00463 Isocitrate lyase family 251 426 4.4E-46 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 SMD11_RS18000 2b1a424aa6d4c2845ec13b084afb0aa9 154 PRINTS PR01217 Proline rich extensin signature 69 90 1.5E-11 T 06-07-2017 SMD11_RS18000 2b1a424aa6d4c2845ec13b084afb0aa9 154 PRINTS PR01217 Proline rich extensin signature 92 108 1.5E-11 T 06-07-2017 SMD11_RS18000 2b1a424aa6d4c2845ec13b084afb0aa9 154 PRINTS PR01217 Proline rich extensin signature 16 28 1.5E-11 T 06-07-2017 SMD11_RS18000 2b1a424aa6d4c2845ec13b084afb0aa9 154 PRINTS PR01217 Proline rich extensin signature 31 47 1.5E-11 T 06-07-2017 SMD11_RS18000 2b1a424aa6d4c2845ec13b084afb0aa9 154 PRINTS PR01217 Proline rich extensin signature 130 154 1.5E-11 T 06-07-2017 SMD11_RS18000 2b1a424aa6d4c2845ec13b084afb0aa9 154 PRINTS PR01217 Proline rich extensin signature 111 128 1.5E-11 T 06-07-2017 SMD11_RS21935 ca5c3a2d398c4a4b63ab144e535b6c1f 307 Pfam PF03466 LysR substrate binding domain 88 292 3.2E-44 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS21935 ca5c3a2d398c4a4b63ab144e535b6c1f 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS21935 ca5c3a2d398c4a4b63ab144e535b6c1f 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS21935 ca5c3a2d398c4a4b63ab144e535b6c1f 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS21935 ca5c3a2d398c4a4b63ab144e535b6c1f 307 Gene3D G3DSA:3.40.190.10 178 266 4.5E-22 T 06-07-2017 SMD11_RS21935 ca5c3a2d398c4a4b63ab144e535b6c1f 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.0E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS21935 ca5c3a2d398c4a4b63ab144e535b6c1f 307 Gene3D G3DSA:3.40.190.10 90 177 3.5E-17 T 06-07-2017 SMD11_RS21935 ca5c3a2d398c4a4b63ab144e535b6c1f 307 Gene3D G3DSA:1.10.10.10 2 84 1.5E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21935 ca5c3a2d398c4a4b63ab144e535b6c1f 307 SUPERFAMILY SSF46785 3 110 1.36E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21935 ca5c3a2d398c4a4b63ab144e535b6c1f 307 SUPERFAMILY SSF53850 90 293 3.45E-41 T 06-07-2017 SMD11_RS20695 fa959badac91e458bf07bf7d8c7a446e 1289 SUPERFAMILY SSF53448 36 115 8.44E-33 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20695 fa959badac91e458bf07bf7d8c7a446e 1289 SUPERFAMILY SSF53448 167 303 8.44E-33 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20695 fa959badac91e458bf07bf7d8c7a446e 1289 Gene3D G3DSA:3.90.550.10 168 304 3.6E-33 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20695 fa959badac91e458bf07bf7d8c7a446e 1289 Gene3D G3DSA:3.90.550.10 39 116 3.6E-33 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20695 fa959badac91e458bf07bf7d8c7a446e 1289 Pfam PF13641 Glycosyltransferase like family 2 65 303 8.8E-17 T 06-07-2017 SMD11_RS09510 28d5fde20d4cbe116e888462da5300bb 259 Gene3D G3DSA:3.40.1160.10 14 253 2.7E-83 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS09510 28d5fde20d4cbe116e888462da5300bb 259 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 22 253 3.5E-90 T 06-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 SMD11_RS09510 28d5fde20d4cbe116e888462da5300bb 259 Pfam PF00696 Amino acid kinase family 24 231 3.7E-25 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS09510 28d5fde20d4cbe116e888462da5300bb 259 SUPERFAMILY SSF53633 21 254 1.7E-69 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS09510 28d5fde20d4cbe116e888462da5300bb 259 Hamap MF_01220_B Uridylate kinase [pyrH]. 19 253 42.512 T 06-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 SMD11_RS09510 28d5fde20d4cbe116e888462da5300bb 259 PIRSF PIRSF005650 17 259 2.9E-88 T 06-07-2017 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 SMD11_RS02725 69fb65415f4c39b188da4b7c8fcf6c65 584 Pfam PF03068 Protein-arginine deiminase (PAD) 182 583 2.1E-75 T 06-07-2017 IPR013530 Protein-arginine deiminase, C-terminal GO:0004668|GO:0005509|GO:0005737 MetaCyc: PWY-4921|Reactome: R-HSA-3247509 SMD11_RS02725 69fb65415f4c39b188da4b7c8fcf6c65 584 SUPERFAMILY SSF55909 228 582 2.16E-50 T 06-07-2017 SMD11_RS33935 7d9743fbdb876e7e08e772da06fcf80c 461 SUPERFAMILY SSF103473 20 393 7.72E-23 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS33935 7d9743fbdb876e7e08e772da06fcf80c 461 Pfam PF07690 Major Facilitator Superfamily 227 403 4.8E-10 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS33935 7d9743fbdb876e7e08e772da06fcf80c 461 Gene3D G3DSA:1.20.1250.20 212 390 2.5E-12 T 06-07-2017 SMD11_RS33935 7d9743fbdb876e7e08e772da06fcf80c 461 Gene3D G3DSA:1.20.1250.20 26 201 1.0E-4 T 06-07-2017 SMD11_RS17280 afcbaa7099d68b6223155c90dfe432c1 599 Gene3D G3DSA:2.120.10.30 173 467 2.3E-43 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS17280 afcbaa7099d68b6223155c90dfe432c1 599 SUPERFAMILY SSF101898 164 465 6.28E-36 T 06-07-2017 SMD11_RS17280 afcbaa7099d68b6223155c90dfe432c1 599 Gene3D G3DSA:3.40.30.10 10 149 1.2E-39 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS17280 afcbaa7099d68b6223155c90dfe432c1 599 Pfam PF13905 Thioredoxin-like 33 127 8.5E-12 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS17280 afcbaa7099d68b6223155c90dfe432c1 599 SUPERFAMILY SSF52833 20 159 2.94E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS17280 afcbaa7099d68b6223155c90dfe432c1 599 Pfam PF01436 NHL repeat 224 249 1.4E-4 T 06-07-2017 IPR001258 NHL repeat GO:0005515 SMD11_RS17280 afcbaa7099d68b6223155c90dfe432c1 599 Pfam PF01436 NHL repeat 395 422 1.5E-4 T 06-07-2017 IPR001258 NHL repeat GO:0005515 SMD11_RS25400 6d1e25b6dd99a117354f38024bfadfd7 415 Pfam PF01384 Phosphate transporter family 22 322 7.1E-75 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 SMD11_RS05260 f7580d67eabc93f0a6375461cb59e0e9 223 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 15 218 7.0E-48 T 06-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like SMD11_RS05260 f7580d67eabc93f0a6375461cb59e0e9 223 Gene3D G3DSA:2.60.120.590 11 218 9.2E-52 T 06-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like SMD11_RS05260 f7580d67eabc93f0a6375461cb59e0e9 223 SUPERFAMILY SSF51197 13 219 6.87E-46 T 06-07-2017 SMD11_RS12225 a27b6f655ad2dc2b41ae2dd336d924d6 334 SUPERFAMILY SSF53850 117 329 6.05E-38 T 06-07-2017 SMD11_RS12225 a27b6f655ad2dc2b41ae2dd336d924d6 334 Gene3D G3DSA:1.10.10.10 29 108 5.1E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12225 a27b6f655ad2dc2b41ae2dd336d924d6 334 SUPERFAMILY SSF46785 28 138 3.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12225 a27b6f655ad2dc2b41ae2dd336d924d6 334 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 57 67 3.5E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS12225 a27b6f655ad2dc2b41ae2dd336d924d6 334 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 3.5E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS12225 a27b6f655ad2dc2b41ae2dd336d924d6 334 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 67 78 3.5E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS12225 a27b6f655ad2dc2b41ae2dd336d924d6 334 Gene3D G3DSA:3.40.190.10 118 203 1.7E-19 T 06-07-2017 SMD11_RS12225 a27b6f655ad2dc2b41ae2dd336d924d6 334 Gene3D G3DSA:3.40.190.10 204 298 5.1E-26 T 06-07-2017 SMD11_RS12225 a27b6f655ad2dc2b41ae2dd336d924d6 334 Pfam PF03466 LysR substrate binding domain 116 324 9.4E-44 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS12225 a27b6f655ad2dc2b41ae2dd336d924d6 334 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 31 90 2.2E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS06630 c4cbd39238d941bfd99900acefde04c9 449 Gene3D G3DSA:3.90.1150.10 323 437 1.8E-32 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS06630 c4cbd39238d941bfd99900acefde04c9 449 Gene3D G3DSA:3.40.640.10 73 322 1.9E-66 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS06630 c4cbd39238d941bfd99900acefde04c9 449 Pfam PF00202 Aminotransferase class-III 38 436 2.7E-79 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS06630 c4cbd39238d941bfd99900acefde04c9 449 SUPERFAMILY SSF53383 18 437 1.03E-100 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS15985 5d49ccaad8cdd9e1a3daf0c432e85595 391 Pfam PF01474 Class-II DAHP synthetase family 182 385 8.3E-80 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMD11_RS15985 5d49ccaad8cdd9e1a3daf0c432e85595 391 Pfam PF01474 Class-II DAHP synthetase family 9 166 5.9E-46 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMD11_RS15985 5d49ccaad8cdd9e1a3daf0c432e85595 391 SUPERFAMILY SSF51569 8 389 1.03E-140 T 06-07-2017 SMD11_RS27855 62649f5357a17d74919fef3054ff5f05 553 SUPERFAMILY SSF51338 481 504 1.86E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS27855 62649f5357a17d74919fef3054ff5f05 553 SUPERFAMILY SSF51338 7 70 1.86E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS27855 62649f5357a17d74919fef3054ff5f05 553 Gene3D G3DSA:2.30.40.10 15 79 6.4E-11 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS27855 62649f5357a17d74919fef3054ff5f05 553 Gene3D G3DSA:3.20.20.140 198 478 3.8E-31 T 06-07-2017 SMD11_RS27855 62649f5357a17d74919fef3054ff5f05 553 Gene3D G3DSA:3.20.20.140 80 91 3.8E-31 T 06-07-2017 SMD11_RS27855 62649f5357a17d74919fef3054ff5f05 553 Pfam PF07969 Amidohydrolase family 58 545 1.2E-96 T 06-07-2017 IPR013108 Amidohydrolase 3 SMD11_RS27855 62649f5357a17d74919fef3054ff5f05 553 SUPERFAMILY SSF51556 69 130 7.19E-35 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS27855 62649f5357a17d74919fef3054ff5f05 553 SUPERFAMILY SSF51556 196 479 7.19E-35 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS26505 d28885e046fb152ac8783c1f7ecab2af 588 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 269 417 6.2E-48 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS26505 d28885e046fb152ac8783c1f7ecab2af 588 ProSitePatterns PS00674 AAA-protein family signature. 387 405 - T 06-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 SMD11_RS26505 d28885e046fb152ac8783c1f7ecab2af 588 SMART SM00382 265 419 1.2E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS26505 d28885e046fb152ac8783c1f7ecab2af 588 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 54 566 50.43 T 06-07-2017 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 SMD11_RS26505 d28885e046fb152ac8783c1f7ecab2af 588 Pfam PF16450 Proteasomal ATPase OB/ID domain 97 226 2.3E-54 T 06-07-2017 IPR032501 Proteasomal ATPase, OB/ID domain SMD11_RS26505 d28885e046fb152ac8783c1f7ecab2af 588 SUPERFAMILY SSF52540 475 514 1.9E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26505 d28885e046fb152ac8783c1f7ecab2af 588 SUPERFAMILY SSF52540 227 434 1.9E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26505 d28885e046fb152ac8783c1f7ecab2af 588 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 52 565 5.3E-254 T 06-07-2017 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 SMD11_RS26505 d28885e046fb152ac8783c1f7ecab2af 588 Gene3D G3DSA:3.40.50.300 217 432 2.9E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14590 979decbaaf624ada8ca7c0286b0b43ce 312 SUPERFAMILY SSF89392 122 294 3.06E-9 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX SMD11_RS34625 58c3339b84664f625fd50f2aaea159b6 376 PIRSF PIRSF015921 32 370 4.7E-70 T 06-07-2017 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 SMD11_RS34625 58c3339b84664f625fd50f2aaea159b6 376 Pfam PF00487 Fatty acid desaturase 85 344 6.8E-42 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 SMD11_RS00615 58c3339b84664f625fd50f2aaea159b6 376 PIRSF PIRSF015921 32 370 4.7E-70 T 06-07-2017 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 SMD11_RS00615 58c3339b84664f625fd50f2aaea159b6 376 Pfam PF00487 Fatty acid desaturase 85 344 6.8E-42 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 SMD11_RS18340 f0f65e55a40a428fea2bf8206d102051 111 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 4 109 6.2E-42 T 06-07-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 SMD11_RS18340 f0f65e55a40a428fea2bf8206d102051 111 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 109 20.652 T 06-07-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 SMD11_RS18340 f0f65e55a40a428fea2bf8206d102051 111 SUPERFAMILY SSF103481 10 108 1.44E-10 T 06-07-2017 SMD11_RS30010 247ccf06afcdba8c80e02966b460370a 458 SUPERFAMILY SSF55797 202 322 1.41E-10 T 06-07-2017 IPR014044 CAP domain SMD11_RS30010 247ccf06afcdba8c80e02966b460370a 458 Pfam PF00188 Cysteine-rich secretory protein family 338 454 4.1E-25 T 06-07-2017 IPR014044 CAP domain SMD11_RS30010 247ccf06afcdba8c80e02966b460370a 458 Pfam PF00188 Cysteine-rich secretory protein family 204 319 2.9E-8 T 06-07-2017 IPR014044 CAP domain SMD11_RS30010 247ccf06afcdba8c80e02966b460370a 458 Gene3D G3DSA:3.40.33.10 333 458 3.4E-15 T 06-07-2017 IPR014044 CAP domain SMD11_RS30010 247ccf06afcdba8c80e02966b460370a 458 Gene3D G3DSA:3.40.33.10 197 250 6.4E-5 T 06-07-2017 IPR014044 CAP domain SMD11_RS30010 247ccf06afcdba8c80e02966b460370a 458 Gene3D G3DSA:2.60.60.30 26 151 3.8E-13 T 06-07-2017 SMD11_RS30010 247ccf06afcdba8c80e02966b460370a 458 Pfam PF02342 TerD domain 25 153 8.6E-15 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS30010 247ccf06afcdba8c80e02966b460370a 458 SUPERFAMILY SSF55797 333 458 8.5E-28 T 06-07-2017 IPR014044 CAP domain SMD11_RS15265 5c3fa7c86d7d407c57415f2907a75fd8 406 SUPERFAMILY SSF52540 4 230 8.5E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15265 5c3fa7c86d7d407c57415f2907a75fd8 406 Pfam PF13177 DNA polymerase III, delta subunit 43 191 1.4E-34 T 06-07-2017 SMD11_RS15265 5c3fa7c86d7d407c57415f2907a75fd8 406 Gene3D G3DSA:3.40.50.300 4 191 4.9E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19390 3e45a2c72bdb9937d9daf8cff917d671 391 Gene3D G3DSA:3.40.47.10 244 355 2.2E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS19390 3e45a2c72bdb9937d9daf8cff917d671 391 Gene3D G3DSA:3.40.47.10 147 184 2.2E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS19390 3e45a2c72bdb9937d9daf8cff917d671 391 Gene3D G3DSA:3.40.47.10 199 223 3.9E-9 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS19390 3e45a2c72bdb9937d9daf8cff917d671 391 Gene3D G3DSA:3.40.47.10 26 114 3.9E-9 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS19390 3e45a2c72bdb9937d9daf8cff917d671 391 Pfam PF02803 Thiolase, C-terminal domain 247 353 1.2E-6 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD11_RS19390 3e45a2c72bdb9937d9daf8cff917d671 391 PIRSF PIRSF000429 4 363 2.2E-25 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS19390 3e45a2c72bdb9937d9daf8cff917d671 391 SUPERFAMILY SSF53901 9 228 2.8E-17 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS19390 3e45a2c72bdb9937d9daf8cff917d671 391 SUPERFAMILY SSF53901 233 356 2.19E-21 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS07910 2d62c3ab0d444d0e25ceda23bd5dcd53 374 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 121 133 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 SMD11_RS07910 2d62c3ab0d444d0e25ceda23bd5dcd53 374 Gene3D G3DSA:1.20.140.10 214 373 1.1E-52 T 06-07-2017 SMD11_RS07910 2d62c3ab0d444d0e25ceda23bd5dcd53 374 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 114 1.8E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS07910 2d62c3ab0d444d0e25ceda23bd5dcd53 374 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 223 372 1.7E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS07910 2d62c3ab0d444d0e25ceda23bd5dcd53 374 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 119 196 2.1E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS07910 2d62c3ab0d444d0e25ceda23bd5dcd53 374 Gene3D G3DSA:2.40.110.10 118 213 9.2E-29 T 06-07-2017 SMD11_RS07910 2d62c3ab0d444d0e25ceda23bd5dcd53 374 SUPERFAMILY SSF47203 221 373 1.61E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS07910 2d62c3ab0d444d0e25ceda23bd5dcd53 374 SUPERFAMILY SSF56645 4 233 1.24E-51 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS07910 2d62c3ab0d444d0e25ceda23bd5dcd53 374 Gene3D G3DSA:1.10.540.10 4 115 1.6E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS10325 2e6689f79a079042ca8757fe7258eb72 77 SUPERFAMILY SSF47473 11 73 1.68E-17 T 06-07-2017 IPR011992 EF-hand domain pair SMD11_RS10325 2e6689f79a079042ca8757fe7258eb72 77 ProSitePatterns PS00018 EF-hand calcium-binding domain. 22 34 - T 06-07-2017 IPR018247 EF-Hand 1, calcium-binding site SMD11_RS10325 2e6689f79a079042ca8757fe7258eb72 77 Gene3D G3DSA:1.10.238.10 8 72 3.6E-18 T 06-07-2017 IPR011992 EF-hand domain pair SMD11_RS10325 2e6689f79a079042ca8757fe7258eb72 77 ProSitePatterns PS00018 EF-hand calcium-binding domain. 59 71 - T 06-07-2017 IPR018247 EF-Hand 1, calcium-binding site SMD11_RS10325 2e6689f79a079042ca8757fe7258eb72 77 Pfam PF13499 EF-hand domain pair 13 71 8.2E-12 T 06-07-2017 IPR002048 EF-hand domain GO:0005509 SMD11_RS10325 2e6689f79a079042ca8757fe7258eb72 77 SMART SM00054 13 41 3.7E-5 T 06-07-2017 IPR002048 EF-hand domain GO:0005509 SMD11_RS10325 2e6689f79a079042ca8757fe7258eb72 77 SMART SM00054 50 75 28.0 T 06-07-2017 IPR002048 EF-hand domain GO:0005509 SMD11_RS16185 732b3166ecb4a23f2fbc2618c23f9222 179 Gene3D G3DSA:1.10.10.10 111 171 1.4E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16185 732b3166ecb4a23f2fbc2618c23f9222 179 Pfam PF04542 Sigma-70 region 2 25 89 8.0E-8 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16185 732b3166ecb4a23f2fbc2618c23f9222 179 Pfam PF08281 Sigma-70, region 4 116 169 2.7E-16 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16185 732b3166ecb4a23f2fbc2618c23f9222 179 SUPERFAMILY SSF88659 109 171 6.54E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16185 732b3166ecb4a23f2fbc2618c23f9222 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 171 5.5E-23 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16185 732b3166ecb4a23f2fbc2618c23f9222 179 Gene3D G3DSA:1.10.1740.10 19 91 6.2E-13 T 06-07-2017 SMD11_RS16185 732b3166ecb4a23f2fbc2618c23f9222 179 SUPERFAMILY SSF88946 20 108 1.33E-12 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16185 732b3166ecb4a23f2fbc2618c23f9222 179 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 19 175 6.6E-60 T 06-07-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 SMD11_RS25175 a2e6d290dced478560a51ce7d4c8f2c9 340 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 51 338 19.022 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 SMD11_RS25175 a2e6d290dced478560a51ce7d4c8f2c9 340 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 106 128 - T 06-07-2017 IPR030470 UbiA prenyltransferase conserved site SMD11_RS25175 a2e6d290dced478560a51ce7d4c8f2c9 340 Pfam PF01040 UbiA prenyltransferase family 67 322 1.1E-62 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 SMD11_RS25175 a2e6d290dced478560a51ce7d4c8f2c9 340 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 53 336 2.2E-95 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 SMD11_RS09665 abbe8c8a0bdf9d771b5c80ded5d5fd49 467 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 16 466 3.6E-96 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMD11_RS09665 abbe8c8a0bdf9d771b5c80ded5d5fd49 467 PRINTS PR00171 Sugar transporter signature 372 393 5.3E-21 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMD11_RS09665 abbe8c8a0bdf9d771b5c80ded5d5fd49 467 PRINTS PR00171 Sugar transporter signature 395 407 5.3E-21 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMD11_RS09665 abbe8c8a0bdf9d771b5c80ded5d5fd49 467 PRINTS PR00171 Sugar transporter signature 29 39 5.3E-21 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMD11_RS09665 abbe8c8a0bdf9d771b5c80ded5d5fd49 467 PRINTS PR00171 Sugar transporter signature 279 289 5.3E-21 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMD11_RS09665 abbe8c8a0bdf9d771b5c80ded5d5fd49 467 PRINTS PR00171 Sugar transporter signature 112 131 5.3E-21 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 SMD11_RS09665 abbe8c8a0bdf9d771b5c80ded5d5fd49 467 SUPERFAMILY SSF103473 18 466 2.22E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS09665 abbe8c8a0bdf9d771b5c80ded5d5fd49 467 Pfam PF00083 Sugar (and other) transporter 22 466 5.5E-101 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMD11_RS09665 abbe8c8a0bdf9d771b5c80ded5d5fd49 467 ProSitePatterns PS00216 Sugar transport proteins signature 1. 323 340 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS09665 abbe8c8a0bdf9d771b5c80ded5d5fd49 467 ProSitePatterns PS00217 Sugar transport proteins signature 2. 117 142 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS09665 abbe8c8a0bdf9d771b5c80ded5d5fd49 467 Gene3D G3DSA:1.20.1250.20 24 211 8.6E-21 T 06-07-2017 SMD11_RS09665 abbe8c8a0bdf9d771b5c80ded5d5fd49 467 Gene3D G3DSA:1.20.1250.20 269 465 4.6E-19 T 06-07-2017 SMD11_RS29985 566ed7549895d1b90e0d06058bd18daf 229 SUPERFAMILY SSF52777 2 203 1.06E-44 T 06-07-2017 SMD11_RS29985 566ed7549895d1b90e0d06058bd18daf 229 Pfam PF00668 Condensation domain 4 71 2.2E-11 T 06-07-2017 IPR001242 Condensation domain SMD11_RS29985 566ed7549895d1b90e0d06058bd18daf 229 Pfam PF13745 HxxPF-repeated domain 94 186 9.0E-30 T 06-07-2017 SMD11_RS00925 fdeb3dc8dcdba7855d3176f1a336bc50 511 Pfam PF00501 AMP-binding enzyme 15 404 5.8E-76 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS00925 fdeb3dc8dcdba7855d3176f1a336bc50 511 Gene3D G3DSA:3.40.50.980 165 311 3.3E-24 T 06-07-2017 SMD11_RS00925 fdeb3dc8dcdba7855d3176f1a336bc50 511 Gene3D G3DSA:3.30.300.30 399 497 3.6E-31 T 06-07-2017 SMD11_RS00925 fdeb3dc8dcdba7855d3176f1a336bc50 511 SUPERFAMILY SSF56801 6 500 1.13E-118 T 06-07-2017 SMD11_RS00925 fdeb3dc8dcdba7855d3176f1a336bc50 511 Gene3D G3DSA:3.40.50.980 14 164 7.6E-23 T 06-07-2017 SMD11_RS00925 fdeb3dc8dcdba7855d3176f1a336bc50 511 Gene3D G3DSA:2.30.38.10 322 398 2.6E-22 T 06-07-2017 SMD11_RS00925 fdeb3dc8dcdba7855d3176f1a336bc50 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 488 3.4E-17 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS13535 17d0e6fcbf2b360617de74e0b66b2a8a 187 Pfam PF04542 Sigma-70 region 2 28 95 9.5E-10 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS13535 17d0e6fcbf2b360617de74e0b66b2a8a 187 Gene3D G3DSA:1.10.10.10 122 169 2.8E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13535 17d0e6fcbf2b360617de74e0b66b2a8a 187 SUPERFAMILY SSF88946 10 107 1.96E-13 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS13535 17d0e6fcbf2b360617de74e0b66b2a8a 187 Gene3D G3DSA:1.10.1740.10 10 115 8.3E-15 T 06-07-2017 SMD11_RS13535 17d0e6fcbf2b360617de74e0b66b2a8a 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 168 1.2E-15 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS13535 17d0e6fcbf2b360617de74e0b66b2a8a 187 SUPERFAMILY SSF88659 117 169 8.63E-6 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS21370 b5be4cab97f8151507aa731621cbebed 59 Pfam PF11755 Protein of unknown function (DUF3311) 3 58 7.5E-13 T 06-07-2017 IPR021741 Protein of unknown function DUF3311 SMD11_RS32160 1d5299bf0fe934aba277ab62b8929e23 145 Pfam PF13581 Histidine kinase-like ATPase domain 1 86 3.2E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS32160 1d5299bf0fe934aba277ab62b8929e23 145 Gene3D G3DSA:3.30.565.10 9 109 6.2E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS32160 1d5299bf0fe934aba277ab62b8929e23 145 SUPERFAMILY SSF55874 26 116 4.07E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS18345 d1d4985b92e222c4eb8cc074bbdd02e7 308 SUPERFAMILY SSF52091 190 291 2.35E-15 T 06-07-2017 IPR002645 STAS domain SMD11_RS18345 d1d4985b92e222c4eb8cc074bbdd02e7 308 Gene3D G3DSA:3.30.750.24 190 291 1.4E-17 T 06-07-2017 IPR002645 STAS domain SMD11_RS18345 d1d4985b92e222c4eb8cc074bbdd02e7 308 Pfam PF13466 STAS domain 200 279 7.1E-11 T 06-07-2017 IPR002645 STAS domain SMD11_RS08150 efc6333a5609be4b2113be9c86ad950e 391 SUPERFAMILY SSF55729 202 314 4.72E-9 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS08150 efc6333a5609be4b2113be9c86ad950e 391 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 29 135 1.3E-17 T 06-07-2017 IPR010033 HAD-superfamily phosphatase, subfamily IIIC SMD11_RS08150 efc6333a5609be4b2113be9c86ad950e 391 TIGRFAM TIGR01686 FkbH: FkbH domain 26 334 1.4E-108 T 06-07-2017 IPR010037 FkbH domain SMD11_RS08150 efc6333a5609be4b2113be9c86ad950e 391 SUPERFAMILY SSF56784 27 130 2.8E-17 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS08150 efc6333a5609be4b2113be9c86ad950e 391 Gene3D G3DSA:3.40.630.30 203 313 3.0E-8 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS08150 efc6333a5609be4b2113be9c86ad950e 391 Gene3D G3DSA:3.40.50.1000 27 132 3.3E-21 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS08940 cefff62c2919f34c7180af5b0499776b 130 SUPERFAMILY SSF52821 10 124 4.85E-21 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS08940 cefff62c2919f34c7180af5b0499776b 130 Gene3D G3DSA:3.40.250.10 5 123 1.2E-20 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS08940 cefff62c2919f34c7180af5b0499776b 130 Pfam PF00581 Rhodanese-like domain 20 117 7.8E-9 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS08940 cefff62c2919f34c7180af5b0499776b 130 SMART SM00450 17 121 2.2E-15 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS20005 5cf237f795df2477f83966773ba9dc7e 156 SUPERFAMILY SSF55811 6 150 2.17E-35 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS20005 5cf237f795df2477f83966773ba9dc7e 156 Pfam PF00293 NUDIX domain 19 135 1.3E-19 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS20005 5cf237f795df2477f83966773ba9dc7e 156 PRINTS PR00502 NUDIX hydrolase family signature 58 73 2.0E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS20005 5cf237f795df2477f83966773ba9dc7e 156 PRINTS PR00502 NUDIX hydrolase family signature 44 58 2.0E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS20005 5cf237f795df2477f83966773ba9dc7e 156 Gene3D G3DSA:3.90.79.10 7 149 4.3E-36 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS18250 c7bf03de82ba39bc6de0157c1cbaa168 353 Gene3D G3DSA:3.40.1130.10 111 265 8.4E-7 T 06-07-2017 SMD11_RS18250 c7bf03de82ba39bc6de0157c1cbaa168 353 SMART SM00563 140 259 1.1E-18 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD11_RS18250 c7bf03de82ba39bc6de0157c1cbaa168 353 Pfam PF01553 Acyltransferase 125 256 6.1E-18 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD11_RS18250 c7bf03de82ba39bc6de0157c1cbaa168 353 SUPERFAMILY SSF69593 117 344 1.44E-34 T 06-07-2017 SMD11_RS18625 002e7f2ad75c728af1af819c7fb7795f 400 Gene3D G3DSA:3.40.50.720 5 40 4.3E-5 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18625 002e7f2ad75c728af1af819c7fb7795f 400 SUPERFAMILY SSF51905 5 39 1.43E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18625 002e7f2ad75c728af1af819c7fb7795f 400 SUPERFAMILY SSF51905 84 383 1.43E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18625 002e7f2ad75c728af1af819c7fb7795f 400 Gene3D G3DSA:3.50.50.60 192 372 3.7E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18625 002e7f2ad75c728af1af819c7fb7795f 400 Gene3D G3DSA:3.50.50.60 107 191 1.0E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18625 002e7f2ad75c728af1af819c7fb7795f 400 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 5 220 4.0E-15 T 06-07-2017 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase SMD11_RS18625 002e7f2ad75c728af1af819c7fb7795f 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 371 2.2E-10 T 06-07-2017 SMD11_RS18625 002e7f2ad75c728af1af819c7fb7795f 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.2E-10 T 06-07-2017 SMD11_RS18625 002e7f2ad75c728af1af819c7fb7795f 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 2.2E-10 T 06-07-2017 SMD11_RS18625 002e7f2ad75c728af1af819c7fb7795f 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 181 199 2.2E-10 T 06-07-2017 SMD11_RS18625 002e7f2ad75c728af1af819c7fb7795f 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 4.0E-6 T 06-07-2017 SMD11_RS18625 002e7f2ad75c728af1af819c7fb7795f 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 181 206 4.0E-6 T 06-07-2017 SMD11_RS16360 599ee5f2dad7fcc8c71b096d36b1f1ba 229 SMART SM00448 4 118 2.4E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS16360 599ee5f2dad7fcc8c71b096d36b1f1ba 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 200 6.3E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16360 599ee5f2dad7fcc8c71b096d36b1f1ba 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 1.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16360 599ee5f2dad7fcc8c71b096d36b1f1ba 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 1.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16360 599ee5f2dad7fcc8c71b096d36b1f1ba 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 1.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16360 599ee5f2dad7fcc8c71b096d36b1f1ba 229 SMART SM00421 145 202 8.7E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16360 599ee5f2dad7fcc8c71b096d36b1f1ba 229 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS16360 599ee5f2dad7fcc8c71b096d36b1f1ba 229 SUPERFAMILY SSF52172 3 122 1.29E-24 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS16360 599ee5f2dad7fcc8c71b096d36b1f1ba 229 Gene3D G3DSA:3.40.50.2300 2 149 2.5E-28 T 06-07-2017 SMD11_RS16360 599ee5f2dad7fcc8c71b096d36b1f1ba 229 Gene3D G3DSA:1.10.10.10 150 209 1.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16360 599ee5f2dad7fcc8c71b096d36b1f1ba 229 Pfam PF00072 Response regulator receiver domain 6 118 1.5E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS16360 599ee5f2dad7fcc8c71b096d36b1f1ba 229 SUPERFAMILY SSF46894 137 209 1.36E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS07160 c3b74581f2b1ad4c3690d638dc85136c 168 SUPERFAMILY SSF53155 1 85 5.89E-12 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS07160 c3b74581f2b1ad4c3690d638dc85136c 168 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 82 162 2.3E-29 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS07160 c3b74581f2b1ad4c3690d638dc85136c 168 Gene3D G3DSA:1.10.10.10 79 163 4.2E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07160 c3b74581f2b1ad4c3690d638dc85136c 168 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 81 161 1.2E-30 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS07160 c3b74581f2b1ad4c3690d638dc85136c 168 SUPERFAMILY SSF46767 80 162 8.89E-28 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS18105 9eb190d3fe272d322a04d7beff04a0f5 268 Gene3D G3DSA:3.40.50.150 95 221 4.5E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS18105 9eb190d3fe272d322a04d7beff04a0f5 268 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 50 266 28.65 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 SMD11_RS18105 9eb190d3fe272d322a04d7beff04a0f5 268 SUPERFAMILY SSF53335 41 265 3.77E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS18105 9eb190d3fe272d322a04d7beff04a0f5 268 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 88 266 1.2E-45 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 SMD11_RS18105 9eb190d3fe272d322a04d7beff04a0f5 268 Pfam PF02390 Putative methyltransferase 93 260 1.5E-49 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 SMD11_RS15165 6957e730d54bb1e502ceca69017e86ff 121 SUPERFAMILY SSF46785 7 78 9.75E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15165 6957e730d54bb1e502ceca69017e86ff 121 SMART SM00345 15 74 3.2E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS15165 6957e730d54bb1e502ceca69017e86ff 121 Gene3D G3DSA:1.10.10.10 13 79 9.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15165 6957e730d54bb1e502ceca69017e86ff 121 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 8.2E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS31840 deab931a0d55c739250e5c49e65be5c2 385 SUPERFAMILY SSF56601 46 370 9.28E-73 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS31840 deab931a0d55c739250e5c49e65be5c2 385 Gene3D G3DSA:3.40.710.10 58 371 3.6E-72 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS31840 deab931a0d55c739250e5c49e65be5c2 385 Pfam PF00144 Beta-lactamase 71 375 8.7E-57 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS09550 aab0441b717ab82cc6549b8df2807dc1 119 Gene3D G3DSA:3.40.1350.10 10 118 5.0E-35 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 SMD11_RS09550 aab0441b717ab82cc6549b8df2807dc1 119 Pfam PF02021 Uncharacterised protein family UPF0102 11 102 1.4E-26 T 06-07-2017 IPR003509 Uncharacterised protein family UPF0102 SMD11_RS09550 aab0441b717ab82cc6549b8df2807dc1 119 Hamap MF_00048 UPF0102 protein YraN [yraN]. 4 115 20.171 T 06-07-2017 IPR003509 Uncharacterised protein family UPF0102 SMD11_RS09550 aab0441b717ab82cc6549b8df2807dc1 119 SUPERFAMILY SSF52980 9 104 9.33E-19 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD11_RS01340 7c86ecfe75be131af35ed426ee3fa8a6 549 Pfam PF00005 ABC transporter 379 502 2.5E-17 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS01340 7c86ecfe75be131af35ed426ee3fa8a6 549 Pfam PF00005 ABC transporter 31 199 9.3E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS01340 7c86ecfe75be131af35ed426ee3fa8a6 549 SUPERFAMILY SSF52540 379 537 4.78E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01340 7c86ecfe75be131af35ed426ee3fa8a6 549 Gene3D G3DSA:3.40.50.300 16 112 2.3E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01340 7c86ecfe75be131af35ed426ee3fa8a6 549 Gene3D G3DSA:3.40.50.300 145 242 2.3E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01340 7c86ecfe75be131af35ed426ee3fa8a6 549 ProSitePatterns PS00211 ABC transporters family signature. 171 185 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS01340 7c86ecfe75be131af35ed426ee3fa8a6 549 SMART SM00382 40 244 1.1E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS01340 7c86ecfe75be131af35ed426ee3fa8a6 549 SMART SM00382 383 546 6.8E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS01340 7c86ecfe75be131af35ed426ee3fa8a6 549 SUPERFAMILY SSF52540 16 243 4.74E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01340 7c86ecfe75be131af35ed426ee3fa8a6 549 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS01340 7c86ecfe75be131af35ed426ee3fa8a6 549 Gene3D G3DSA:3.40.50.300 383 539 3.9E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04025 f6bc97ec335256263d49ea5f8bf96679 317 Gene3D G3DSA:1.10.3720.10 91 311 4.6E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS04025 f6bc97ec335256263d49ea5f8bf96679 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 313 4.0E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS04025 f6bc97ec335256263d49ea5f8bf96679 317 SUPERFAMILY SSF161098 93 298 1.83E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS19970 b01e21cb09f717fcd70784629e6e9d2b 509 Pfam PF00743 Flavin-binding monooxygenase-like 10 213 7.1E-14 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 SMD11_RS19970 b01e21cb09f717fcd70784629e6e9d2b 509 SUPERFAMILY SSF51905 280 463 3.71E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS19970 b01e21cb09f717fcd70784629e6e9d2b 509 Gene3D G3DSA:3.50.50.60 5 212 1.3E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS19970 b01e21cb09f717fcd70784629e6e9d2b 509 Gene3D G3DSA:3.50.50.60 319 486 1.3E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS19970 b01e21cb09f717fcd70784629e6e9d2b 509 SUPERFAMILY SSF51905 7 229 2.3E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS19970 b01e21cb09f717fcd70784629e6e9d2b 509 PRINTS PR00419 Adrenodoxin reductase family signature 176 190 8.6E-5 T 06-07-2017 SMD11_RS19970 b01e21cb09f717fcd70784629e6e9d2b 509 PRINTS PR00419 Adrenodoxin reductase family signature 10 32 8.6E-5 T 06-07-2017 SMD11_RS18175 199965176d5111757bff0fa65a6f8a07 291 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 158 1.2E-15 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS18175 199965176d5111757bff0fa65a6f8a07 291 Pfam PF08281 Sigma-70, region 4 105 155 1.5E-11 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS18175 199965176d5111757bff0fa65a6f8a07 291 Pfam PF04542 Sigma-70 region 2 7 69 1.4E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS18175 199965176d5111757bff0fa65a6f8a07 291 SUPERFAMILY SSF54427 167 287 2.85E-17 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS18175 199965176d5111757bff0fa65a6f8a07 291 SUPERFAMILY SSF88946 6 86 1.8E-12 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS18175 199965176d5111757bff0fa65a6f8a07 291 SUPERFAMILY SSF88659 86 160 1.35E-10 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS18175 199965176d5111757bff0fa65a6f8a07 291 Gene3D G3DSA:3.10.450.50 166 286 1.7E-16 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS18175 199965176d5111757bff0fa65a6f8a07 291 Gene3D G3DSA:1.10.1740.10 6 72 1.0E-10 T 06-07-2017 SMD11_RS18175 199965176d5111757bff0fa65a6f8a07 291 Gene3D G3DSA:1.10.10.10 103 159 6.5E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04810 da985c6cd9aeab8f1a5446af7f42bdcb 488 SMART SM00382 281 473 3.0E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS04810 da985c6cd9aeab8f1a5446af7f42bdcb 488 SMART SM00382 34 226 6.4E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS04810 da985c6cd9aeab8f1a5446af7f42bdcb 488 Gene3D G3DSA:3.40.50.300 254 483 2.0E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04810 da985c6cd9aeab8f1a5446af7f42bdcb 488 SUPERFAMILY SSF52540 22 231 9.87E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04810 da985c6cd9aeab8f1a5446af7f42bdcb 488 Pfam PF00005 ABC transporter 29 177 3.3E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS04810 da985c6cd9aeab8f1a5446af7f42bdcb 488 Pfam PF00005 ABC transporter 274 424 2.7E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS04810 da985c6cd9aeab8f1a5446af7f42bdcb 488 SUPERFAMILY SSF52540 254 483 2.62E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04810 da985c6cd9aeab8f1a5446af7f42bdcb 488 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS04810 da985c6cd9aeab8f1a5446af7f42bdcb 488 Gene3D G3DSA:3.40.50.300 11 222 3.1E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04810 da985c6cd9aeab8f1a5446af7f42bdcb 488 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS09400 bc231a559f1288f3212d4a85d4f99ff1 325 Pfam PF01380 SIS domain 31 116 9.1E-7 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 SMD11_RS09400 bc231a559f1288f3212d4a85d4f99ff1 325 SUPERFAMILY SSF53697 14 306 3.48E-33 T 06-07-2017 SMD11_RS09400 bc231a559f1288f3212d4a85d4f99ff1 325 Gene3D G3DSA:3.40.50.10490 5 119 2.2E-15 T 06-07-2017 SMD11_RS09400 bc231a559f1288f3212d4a85d4f99ff1 325 Gene3D G3DSA:3.40.50.10490 183 306 1.3E-10 T 06-07-2017 SMD11_RS31065 339d8388f7bab8d1e2d6aed49d238781 462 SUPERFAMILY SSF103473 63 451 6.41E-34 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS31065 339d8388f7bab8d1e2d6aed49d238781 462 Pfam PF05977 Transmembrane secretion effector 57 451 2.1E-27 T 06-07-2017 IPR010290 Transmembrane secretion effector SMD11_RS31065 339d8388f7bab8d1e2d6aed49d238781 462 Gene3D G3DSA:1.20.1250.20 63 252 4.4E-17 T 06-07-2017 SMD11_RS31065 339d8388f7bab8d1e2d6aed49d238781 462 Gene3D G3DSA:1.20.1250.20 275 452 4.6E-5 T 06-07-2017 SMD11_RS19085 89c4b3222cae96ebb3d3c00f831ca825 331 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 18 330 2.8E-123 T 06-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMD11_RS19085 89c4b3222cae96ebb3d3c00f831ca825 331 Hamap MF_00215 Pantothenate kinase [coaA]. 1 331 172.884 T 06-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMD11_RS19085 89c4b3222cae96ebb3d3c00f831ca825 331 PIRSF PIRSF000545 8 331 1.6E-141 T 06-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SMD11_RS19085 89c4b3222cae96ebb3d3c00f831ca825 331 SUPERFAMILY SSF52540 16 329 7.21E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19085 89c4b3222cae96ebb3d3c00f831ca825 331 Gene3D G3DSA:3.40.50.300 17 329 4.0E-104 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19085 89c4b3222cae96ebb3d3c00f831ca825 331 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 104 247 2.3E-9 T 06-07-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 SMD11_RS17695 590b3de385236c7e1f4b97d4668e0792 388 Pfam PF00155 Aminotransferase class I and II 32 384 3.7E-61 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS17695 590b3de385236c7e1f4b97d4668e0792 388 Gene3D G3DSA:3.90.1150.10 256 388 7.4E-25 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS17695 590b3de385236c7e1f4b97d4668e0792 388 Gene3D G3DSA:3.40.640.10 44 255 1.5E-76 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS17695 590b3de385236c7e1f4b97d4668e0792 388 SUPERFAMILY SSF53383 8 387 1.33E-107 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS29480 12cbd182406013d7ffa1b25769dc030d 183 Gene3D G3DSA:2.60.120.10 56 156 1.1E-14 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS29480 12cbd182406013d7ffa1b25769dc030d 183 Pfam PF07883 Cupin domain 84 152 2.6E-8 T 06-07-2017 IPR013096 Cupin 2, conserved barrel SMD11_RS29480 12cbd182406013d7ffa1b25769dc030d 183 SUPERFAMILY SSF51182 60 175 9.25E-17 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS08115 b483a7d4f8afcf8dd6aa0d665b1e3b98 650 SUPERFAMILY SSF55781 96 246 1.46E-22 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS08115 b483a7d4f8afcf8dd6aa0d665b1e3b98 650 SMART SM00065 94 245 8.7E-21 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS08115 b483a7d4f8afcf8dd6aa0d665b1e3b98 650 Gene3D G3DSA:3.30.450.40 69 251 9.1E-25 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS08115 b483a7d4f8afcf8dd6aa0d665b1e3b98 650 Pfam PF13556 PucR C-terminal helix-turn-helix domain 574 632 4.9E-19 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain SMD11_RS08115 b483a7d4f8afcf8dd6aa0d665b1e3b98 650 Pfam PF13185 GAF domain 96 236 9.5E-10 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS29855 f41cebe5e4387d8c2d1584e761c8b0a0 421 SUPERFAMILY SSF103473 17 399 7.32E-60 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS29855 f41cebe5e4387d8c2d1584e761c8b0a0 421 PRINTS PR01035 Tetracycline resistance protein signature 33 49 1.2E-8 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD11_RS29855 f41cebe5e4387d8c2d1584e761c8b0a0 421 PRINTS PR01035 Tetracycline resistance protein signature 62 81 1.2E-8 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD11_RS29855 f41cebe5e4387d8c2d1584e761c8b0a0 421 PRINTS PR01035 Tetracycline resistance protein signature 179 199 1.2E-8 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD11_RS29855 f41cebe5e4387d8c2d1584e761c8b0a0 421 PRINTS PR01035 Tetracycline resistance protein signature 356 379 1.2E-8 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD11_RS29855 f41cebe5e4387d8c2d1584e761c8b0a0 421 PRINTS PR01035 Tetracycline resistance protein signature 151 173 1.2E-8 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD11_RS29855 f41cebe5e4387d8c2d1584e761c8b0a0 421 Gene3D G3DSA:1.20.1250.20 22 204 3.1E-30 T 06-07-2017 SMD11_RS29855 f41cebe5e4387d8c2d1584e761c8b0a0 421 Gene3D G3DSA:1.20.1250.20 226 399 1.3E-21 T 06-07-2017 SMD11_RS29855 f41cebe5e4387d8c2d1584e761c8b0a0 421 ProSitePatterns PS00216 Sugar transport proteins signature 1. 80 96 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS29855 f41cebe5e4387d8c2d1584e761c8b0a0 421 Pfam PF07690 Major Facilitator Superfamily 27 248 3.0E-27 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS32330 3a33e4f8f1bacbf738f1e69c28271ce2 396 PRINTS PR00359 B-class P450 signature 315 330 8.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32330 3a33e4f8f1bacbf738f1e69c28271ce2 396 PRINTS PR00359 B-class P450 signature 193 215 8.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32330 3a33e4f8f1bacbf738f1e69c28271ce2 396 PRINTS PR00359 B-class P450 signature 157 172 8.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32330 3a33e4f8f1bacbf738f1e69c28271ce2 396 PRINTS PR00359 B-class P450 signature 269 280 8.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32330 3a33e4f8f1bacbf738f1e69c28271ce2 396 PRINTS PR00359 B-class P450 signature 345 356 8.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32330 3a33e4f8f1bacbf738f1e69c28271ce2 396 PRINTS PR00359 B-class P450 signature 287 314 8.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32330 3a33e4f8f1bacbf738f1e69c28271ce2 396 PRINTS PR00359 B-class P450 signature 140 156 8.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32330 3a33e4f8f1bacbf738f1e69c28271ce2 396 PRINTS PR00359 B-class P450 signature 336 345 8.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32330 3a33e4f8f1bacbf738f1e69c28271ce2 396 Pfam PF00067 Cytochrome P450 265 364 1.2E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS32330 3a33e4f8f1bacbf738f1e69c28271ce2 396 Gene3D G3DSA:1.10.630.10 20 396 8.6E-95 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS32330 3a33e4f8f1bacbf738f1e69c28271ce2 396 SUPERFAMILY SSF48264 20 396 9.95E-74 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS31545 3a9fdd8de15a3e34c76181e10101ef55 359 Pfam PF13649 Methyltransferase domain 196 287 5.4E-9 T 06-07-2017 SMD11_RS31545 3a9fdd8de15a3e34c76181e10101ef55 359 Gene3D G3DSA:3.40.50.150 163 335 1.7E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS31545 3a9fdd8de15a3e34c76181e10101ef55 359 SUPERFAMILY SSF53335 161 338 4.41E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS05115 c3d16703e0c1b65947397edd43636377 339 Gene3D G3DSA:3.40.50.720 118 298 2.2E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05115 c3d16703e0c1b65947397edd43636377 339 SUPERFAMILY SSF51735 101 297 3.4E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05115 c3d16703e0c1b65947397edd43636377 339 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMD11_RS05115 c3d16703e0c1b65947397edd43636377 339 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 296 1.1E-49 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMD11_RS05115 c3d16703e0c1b65947397edd43636377 339 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 146 173 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SMD11_RS05115 c3d16703e0c1b65947397edd43636377 339 SUPERFAMILY SSF52283 4 134 2.55E-28 T 06-07-2017 SMD11_RS05115 c3d16703e0c1b65947397edd43636377 339 Gene3D G3DSA:3.40.50.720 23 117 5.5E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05115 c3d16703e0c1b65947397edd43636377 339 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 325 5.9E-21 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SMD11_RS31495 fc8ffad0f2cf1fab878e9f8e7ff80a99 144 SUPERFAMILY SSF103196 22 137 5.93E-25 T 06-07-2017 SMD11_RS31495 fc8ffad0f2cf1fab878e9f8e7ff80a99 144 Gene3D G3DSA:3.30.450.30 17 136 1.6E-30 T 06-07-2017 SMD11_RS31495 fc8ffad0f2cf1fab878e9f8e7ff80a99 144 SMART SM00960 22 110 4.2E-17 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS31495 fc8ffad0f2cf1fab878e9f8e7ff80a99 144 Pfam PF03259 Roadblock/LC7 domain 24 110 1.0E-17 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS11685 8bdde3da2b9926b12ec22b1b78801cb5 573 PIRSF PIRSF002741 9 566 8.6E-69 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD11_RS11685 8bdde3da2b9926b12ec22b1b78801cb5 573 Gene3D G3DSA:3.90.76.10 60 231 6.2E-33 T 06-07-2017 SMD11_RS11685 8bdde3da2b9926b12ec22b1b78801cb5 573 SUPERFAMILY SSF53850 44 571 1.72E-97 T 06-07-2017 SMD11_RS11685 8bdde3da2b9926b12ec22b1b78801cb5 573 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 95 485 1.5E-75 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain SMD11_RS11685 8bdde3da2b9926b12ec22b1b78801cb5 573 Gene3D G3DSA:3.10.105.10 321 543 1.3E-43 T 06-07-2017 SMD11_RS03700 c3841d6b23134bb5bdaf6303d026dcef 687 Pfam PF13520 Amino acid permease 38 462 1.6E-26 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS13495 8b4c54944d6a5c7292b9f71ca58dce97 506 Pfam PF07690 Major Facilitator Superfamily 47 441 1.4E-43 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS13495 8b4c54944d6a5c7292b9f71ca58dce97 506 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 45 453 9.5E-70 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS13495 8b4c54944d6a5c7292b9f71ca58dce97 506 SUPERFAMILY SSF103473 279 497 6.8E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS13495 8b4c54944d6a5c7292b9f71ca58dce97 506 SUPERFAMILY SSF103473 22 221 6.8E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS13495 8b4c54944d6a5c7292b9f71ca58dce97 506 Gene3D G3DSA:1.20.1250.20 40 219 4.6E-25 T 06-07-2017 SMD11_RS13495 8b4c54944d6a5c7292b9f71ca58dce97 506 Gene3D G3DSA:1.20.1250.20 293 494 4.4E-14 T 06-07-2017 SMD11_RS08185 eb35e70476c823b93827c8aa4f88fb00 879 SUPERFAMILY SSF48452 611 673 1.38E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS08185 eb35e70476c823b93827c8aa4f88fb00 879 SUPERFAMILY SSF51905 1 221 7.59E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS08185 eb35e70476c823b93827c8aa4f88fb00 879 Pfam PF13454 FAD-NAD(P)-binding 2 151 7.3E-36 T 06-07-2017 SMD11_RS08185 eb35e70476c823b93827c8aa4f88fb00 879 Gene3D G3DSA:3.50.50.60 1 205 3.3E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS08185 eb35e70476c823b93827c8aa4f88fb00 879 Gene3D G3DSA:3.50.50.60 261 369 2.5E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS08185 eb35e70476c823b93827c8aa4f88fb00 879 Gene3D G3DSA:1.25.40.10 835 865 3.3E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS08185 eb35e70476c823b93827c8aa4f88fb00 879 Gene3D G3DSA:1.25.40.10 601 693 3.3E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS08185 eb35e70476c823b93827c8aa4f88fb00 879 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 188 206 2.9E-6 T 06-07-2017 SMD11_RS08185 eb35e70476c823b93827c8aa4f88fb00 879 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 1 16 2.9E-6 T 06-07-2017 SMD11_RS08185 eb35e70476c823b93827c8aa4f88fb00 879 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 2.9E-6 T 06-07-2017 SMD11_RS30920 4b63e65f968cd185c8f2a566f2cefceb 387 Gene3D G3DSA:3.40.50.2300 205 365 1.0E-7 T 06-07-2017 SMD11_RS30920 4b63e65f968cd185c8f2a566f2cefceb 387 Pfam PF13407 Periplasmic binding protein domain 87 347 2.2E-21 T 06-07-2017 IPR025997 Periplasmic binding protein SMD11_RS30920 4b63e65f968cd185c8f2a566f2cefceb 387 Gene3D G3DSA:3.40.50.2300 82 204 1.4E-11 T 06-07-2017 SMD11_RS30920 4b63e65f968cd185c8f2a566f2cefceb 387 SUPERFAMILY SSF53822 84 365 4.21E-25 T 06-07-2017 IPR028082 Periplasmic binding protein-like I SMD11_RS08990 ee0e2a300674c6aee4207d8c190e0795 127 Pfam PF13560 Helix-turn-helix domain 8 66 2.5E-11 T 06-07-2017 SMD11_RS08990 ee0e2a300674c6aee4207d8c190e0795 127 SUPERFAMILY SSF47413 3 72 3.66E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS08990 ee0e2a300674c6aee4207d8c190e0795 127 Gene3D G3DSA:1.10.260.40 8 73 1.4E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS08990 ee0e2a300674c6aee4207d8c190e0795 127 SMART SM00530 11 66 4.2E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 2 402 5.1E-128 T 06-07-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 Gene3D G3DSA:1.20.200.10 92 356 4.3E-82 T 06-07-2017 SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 Gene3D G3DSA:1.10.40.30 357 399 3.6E-13 T 06-07-2017 SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 SMART SM00998 350 423 2.5E-11 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 PRINTS PR00149 Fumarate lyase superfamily signature 217 244 8.1E-23 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 PRINTS PR00149 Fumarate lyase superfamily signature 262 278 8.1E-23 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 PRINTS PR00149 Fumarate lyase superfamily signature 89 107 8.1E-23 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 8.1E-23 T 06-07-2017 IPR000362 Fumarate lyase family SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 SUPERFAMILY SSF48557 3 417 1.73E-111 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 Pfam PF00206 Lyase 68 282 8.6E-44 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 ProSitePatterns PS00163 Fumarate lyases signature. 262 271 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 PRINTS PR00145 Argininosuccinate lyase family signature 262 278 3.6E-6 T 06-07-2017 SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 PRINTS PR00145 Argininosuccinate lyase family signature 129 149 3.6E-6 T 06-07-2017 SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 PRINTS PR00145 Argininosuccinate lyase family signature 217 241 3.6E-6 T 06-07-2017 SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 Pfam PF10397 Adenylosuccinate lyase C-terminus 351 421 5.4E-12 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SMD11_RS32545 e13b72dc3b4a980422995b390047f264 430 Gene3D G3DSA:1.10.275.10 2 91 1.6E-24 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal SMD11_RS30765 417f5e00f9ee12dac6e9f189b2f2ea3c 436 SUPERFAMILY SSF53383 46 434 1.21E-68 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS30765 417f5e00f9ee12dac6e9f189b2f2ea3c 436 Pfam PF00266 Aminotransferase class-V 96 384 5.5E-35 T 06-07-2017 IPR000192 Aminotransferase class V domain SMD11_RS30765 417f5e00f9ee12dac6e9f189b2f2ea3c 436 Gene3D G3DSA:3.90.1150.10 315 429 2.1E-9 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS30765 417f5e00f9ee12dac6e9f189b2f2ea3c 436 Gene3D G3DSA:3.40.640.10 92 314 1.7E-53 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS13280 470e3f1f2046acdf6af2e9d7171f9a5b 289 Pfam PF00561 alpha/beta hydrolase fold 130 192 3.0E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS13280 470e3f1f2046acdf6af2e9d7171f9a5b 289 Gene3D G3DSA:3.40.50.1820 80 277 2.1E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS13280 470e3f1f2046acdf6af2e9d7171f9a5b 289 SUPERFAMILY SSF53474 81 263 1.55E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 SMART SM00851 974 1065 1.6E-27 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 SUPERFAMILY SSF52440 2 127 3.45E-47 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 SUPERFAMILY SSF56059 128 406 6.72E-100 T 06-07-2017 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 Gene3D G3DSA:3.30.470.20 751 952 8.0E-61 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 Gene3D G3DSA:3.30.470.20 206 405 1.3E-77 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 842 849 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 303 310 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 Gene3D G3DSA:3.40.50.1380 957 1095 4.8E-41 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 SMART SM01096 426 547 1.8E-61 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1074 0.0 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 340 4.1E-66 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 680 879 2.2E-31 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 Pfam PF02142 MGS-like domain 975 1065 2.7E-21 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 Gene3D G3DSA:3.30.1490.20 690 750 2.2E-24 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 Gene3D G3DSA:3.30.1490.20 149 205 1.3E-19 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1086 12.98 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 713 727 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 170 184 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 Gene3D G3DSA:3.40.50.20 3 108 1.6E-42 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 432 547 6.7E-37 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 SUPERFAMILY SSF52335 960 1094 3.01E-33 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 SUPERFAMILY SSF56059 678 951 1.06E-88 T 06-07-2017 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 Gene3D G3DSA:3.40.50.20 539 666 7.4E-57 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 SUPERFAMILY SSF52440 558 678 5.47E-43 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 Gene3D G3DSA:1.10.1030.10 406 538 5.0E-45 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 SUPERFAMILY SSF48108 401 554 1.83E-45 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 245 262 6.9E-63 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 303 332 6.9E-63 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 6.9E-63 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 6.9E-63 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 210 229 6.9E-63 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 385 403 6.9E-63 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS27365 21db2e9b41bd20ead30cc62cefd2cf7c 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 174 186 6.9E-63 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 SMD11_RS29270 47e9bee34d1477156240de7ec277f55f 215 Pfam PF00072 Response regulator receiver domain 10 121 1.5E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS29270 47e9bee34d1477156240de7ec277f55f 215 SUPERFAMILY SSF52172 8 136 4.27E-28 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS29270 47e9bee34d1477156240de7ec277f55f 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS29270 47e9bee34d1477156240de7ec277f55f 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS29270 47e9bee34d1477156240de7ec277f55f 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS29270 47e9bee34d1477156240de7ec277f55f 215 Gene3D G3DSA:3.40.50.2300 7 155 1.5E-32 T 06-07-2017 SMD11_RS29270 47e9bee34d1477156240de7ec277f55f 215 SMART SM00421 151 208 2.0E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS29270 47e9bee34d1477156240de7ec277f55f 215 SUPERFAMILY SSF46894 144 214 1.33E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS29270 47e9bee34d1477156240de7ec277f55f 215 SMART SM00448 8 121 1.1E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS29270 47e9bee34d1477156240de7ec277f55f 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 207 3.5E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS29270 47e9bee34d1477156240de7ec277f55f 215 Gene3D G3DSA:1.10.10.10 156 214 1.8E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04195 8dd33aeb713569bba1ef5b0b19afe448 273 Gene3D G3DSA:3.40.50.1820 17 230 2.3E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04195 8dd33aeb713569bba1ef5b0b19afe448 273 Pfam PF01764 Lipase (class 3) 77 208 2.5E-29 T 06-07-2017 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 SMD11_RS04195 8dd33aeb713569bba1ef5b0b19afe448 273 SUPERFAMILY SSF53474 18 224 4.57E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS16615 dc7d6349e2a6a98ee1f31fdc36c9a965 591 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 127 550 6.9E-212 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SMD11_RS16615 dc7d6349e2a6a98ee1f31fdc36c9a965 591 Pfam PF01964 Radical SAM ThiC family 128 548 1.3E-199 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SMD11_RS16615 dc7d6349e2a6a98ee1f31fdc36c9a965 591 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 127 554 55.76 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SMD11_RS16615 dc7d6349e2a6a98ee1f31fdc36c9a965 591 Pfam PF13667 ThiC-associated domain 18 81 5.1E-21 T 06-07-2017 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 SMD11_RS07650 bf0d168c614f79f02d2586bc8b0b754b 150 Gene3D G3DSA:2.40.50.140 6 112 3.2E-35 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS07650 bf0d168c614f79f02d2586bc8b0b754b 150 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 8 120 4.6E-28 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SMD11_RS07650 bf0d168c614f79f02d2586bc8b0b754b 150 SUPERFAMILY SSF50249 8 150 5.88E-36 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS07650 bf0d168c614f79f02d2586bc8b0b754b 150 Pfam PF00436 Single-strand binding protein family 8 107 2.5E-25 T 06-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 SMD11_RS07650 bf0d168c614f79f02d2586bc8b0b754b 150 Hamap MF_00984 Single-stranded DNA-binding protein. 5 114 26.537 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SMD11_RS05450 5b8ac335ad5ccdcda3099c923b0fda29 545 SMART SM00382 29 232 3.7E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS05450 5b8ac335ad5ccdcda3099c923b0fda29 545 SMART SM00382 374 541 1.6E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS05450 5b8ac335ad5ccdcda3099c923b0fda29 545 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS05450 5b8ac335ad5ccdcda3099c923b0fda29 545 Pfam PF00005 ABC transporter 368 495 1.2E-13 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS05450 5b8ac335ad5ccdcda3099c923b0fda29 545 Pfam PF00005 ABC transporter 23 187 2.0E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS05450 5b8ac335ad5ccdcda3099c923b0fda29 545 SUPERFAMILY SSF52540 363 543 1.2E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05450 5b8ac335ad5ccdcda3099c923b0fda29 545 SUPERFAMILY SSF52540 5 232 2.87E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05450 5b8ac335ad5ccdcda3099c923b0fda29 545 Gene3D G3DSA:3.40.50.300 7 103 5.0E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05450 5b8ac335ad5ccdcda3099c923b0fda29 545 Gene3D G3DSA:3.40.50.300 136 280 5.0E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05450 5b8ac335ad5ccdcda3099c923b0fda29 545 Gene3D G3DSA:3.40.50.300 365 544 9.7E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16630 c131a8fa0cc3b199dfefca1bcc35d194 148 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 7.9E-30 T 06-07-2017 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 SMD11_RS33895 2876d6f6140e88d6f2df5d0b66c008d2 517 Gene3D G3DSA:2.80.10.50 36 171 1.4E-9 T 06-07-2017 SMD11_RS33895 2876d6f6140e88d6f2df5d0b66c008d2 517 SUPERFAMILY SSF50370 30 167 5.15E-9 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS03080 f3defa5a3f79fcd51fd35fd745745f45 336 Gene3D G3DSA:3.60.130.10 189 312 7.0E-51 T 06-07-2017 SMD11_RS03080 f3defa5a3f79fcd51fd35fd745745f45 336 Gene3D G3DSA:3.60.130.10 20 157 7.0E-51 T 06-07-2017 SMD11_RS03080 f3defa5a3f79fcd51fd35fd745745f45 336 SUPERFAMILY SSF51197 8 308 9.16E-64 T 06-07-2017 SMD11_RS03080 f3defa5a3f79fcd51fd35fd745745f45 336 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 27 306 1.1E-42 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMD11_RS30510 dfb4adde9391f06d797c93beaa76c99b 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.6E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS30510 dfb4adde9391f06d797c93beaa76c99b 201 Pfam PF13977 Bacterial transcriptional repressor 87 196 2.7E-21 T 06-07-2017 SMD11_RS30510 dfb4adde9391f06d797c93beaa76c99b 201 SUPERFAMILY SSF48498 84 196 6.81E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS30510 dfb4adde9391f06d797c93beaa76c99b 201 SUPERFAMILY SSF46689 1 82 1.8E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS30510 dfb4adde9391f06d797c93beaa76c99b 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS30510 dfb4adde9391f06d797c93beaa76c99b 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS30510 dfb4adde9391f06d797c93beaa76c99b 201 Gene3D G3DSA:1.10.357.10 1 196 1.4E-45 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS28295 f593e907a675bb11c48448fc521a46d0 195 Gene3D G3DSA:1.10.357.10 12 195 2.0E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS28295 f593e907a675bb11c48448fc521a46d0 195 SUPERFAMILY SSF46689 8 66 2.77E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS28295 f593e907a675bb11c48448fc521a46d0 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.7E-4 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS04550 9768a689c3b796bc38c3ba6d2d1c1815 265 Pfam PF00005 ABC transporter 20 167 8.3E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS04550 9768a689c3b796bc38c3ba6d2d1c1815 265 Gene3D G3DSA:3.40.50.300 2 237 1.7E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04550 9768a689c3b796bc38c3ba6d2d1c1815 265 SUPERFAMILY SSF52540 3 228 1.66E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04550 9768a689c3b796bc38c3ba6d2d1c1815 265 SMART SM00382 27 215 9.0E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 SUPERFAMILY SSF52540 297 560 2.89E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 SUPERFAMILY SSF48452 111 273 7.25E-32 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 PRINTS PR00364 Disease resistance protein signature 494 508 1.4E-10 T 06-07-2017 SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 PRINTS PR00364 Disease resistance protein signature 333 348 1.4E-10 T 06-07-2017 SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 PRINTS PR00364 Disease resistance protein signature 410 424 1.4E-10 T 06-07-2017 SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 SUPERFAMILY SSF48452 883 994 1.9E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 Pfam PF03704 Bacterial transcriptional activator domain 115 259 1.4E-41 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 Gene3D G3DSA:1.25.40.10 124 242 6.8E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 Gene3D G3DSA:1.25.40.10 799 814 6.8E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 Gene3D G3DSA:1.25.40.10 815 834 1.5E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 Gene3D G3DSA:1.25.40.10 879 996 1.5E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 Gene3D G3DSA:1.10.10.10 35 110 5.1E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 Gene3D G3DSA:3.40.50.300 313 426 6.1E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 SUPERFAMILY SSF46894 9 85 4.25E-8 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 Pfam PF00931 NB-ARC domain 317 563 2.3E-8 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 SMART SM00862 23 108 3.8E-4 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 SMART SM01043 115 259 9.2E-47 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS03075 927ced510ad787b5ac1f6000557bd976 1005 Pfam PF00486 Transcriptional regulatory protein, C terminal 35 84 8.2E-5 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS02070 4dadaf4fb81b869284a815413059066e 505 Gene3D G3DSA:1.10.510.10 78 257 2.0E-45 T 06-07-2017 SMD11_RS02070 4dadaf4fb81b869284a815413059066e 505 Gene3D G3DSA:3.30.200.20 4 77 2.1E-27 T 06-07-2017 SMD11_RS02070 4dadaf4fb81b869284a815413059066e 505 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS02070 4dadaf4fb81b869284a815413059066e 505 Pfam PF00069 Protein kinase domain 13 253 1.5E-46 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS02070 4dadaf4fb81b869284a815413059066e 505 SUPERFAMILY SSF56112 9 264 8.41E-71 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS02070 4dadaf4fb81b869284a815413059066e 505 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS02070 4dadaf4fb81b869284a815413059066e 505 SMART SM00220 12 261 6.3E-63 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS28605 fa61d0be877e34c16f43f324106c1b7b 427 SUPERFAMILY SSF103473 15 401 1.96E-39 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS28605 fa61d0be877e34c16f43f324106c1b7b 427 Gene3D G3DSA:1.20.1250.20 15 198 4.0E-17 T 06-07-2017 SMD11_RS28605 fa61d0be877e34c16f43f324106c1b7b 427 Gene3D G3DSA:1.20.1250.20 234 398 2.2E-14 T 06-07-2017 SMD11_RS28605 fa61d0be877e34c16f43f324106c1b7b 427 Pfam PF05977 Transmembrane secretion effector 10 407 9.5E-31 T 06-07-2017 IPR010290 Transmembrane secretion effector SMD11_RS07885 bdc0cfde0cccc83aa355c13376eb1f33 191 SUPERFAMILY SSF101874 22 190 2.35E-57 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS07885 bdc0cfde0cccc83aa355c13376eb1f33 191 Gene3D G3DSA:2.40.128.110 21 190 4.7E-61 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS07885 bdc0cfde0cccc83aa355c13376eb1f33 191 SMART SM00867 21 188 1.8E-68 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS07885 bdc0cfde0cccc83aa355c13376eb1f33 191 Pfam PF04264 YceI-like domain 22 186 1.7E-46 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS21350 c83e6e8bc60a22612552e9aafad2132b 239 SMART SM00448 22 135 7.0E-36 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS21350 c83e6e8bc60a22612552e9aafad2132b 239 Pfam PF00072 Response regulator receiver domain 24 136 2.6E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS21350 c83e6e8bc60a22612552e9aafad2132b 239 SUPERFAMILY SSF46894 161 233 5.1E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS21350 c83e6e8bc60a22612552e9aafad2132b 239 Gene3D G3DSA:1.10.10.10 173 232 1.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21350 c83e6e8bc60a22612552e9aafad2132b 239 SUPERFAMILY SSF52172 21 152 4.84E-35 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS21350 c83e6e8bc60a22612552e9aafad2132b 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 203 215 5.0E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS21350 c83e6e8bc60a22612552e9aafad2132b 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 203 5.0E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS21350 c83e6e8bc60a22612552e9aafad2132b 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 187 5.0E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS21350 c83e6e8bc60a22612552e9aafad2132b 239 SMART SM00421 170 227 3.4E-22 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS21350 c83e6e8bc60a22612552e9aafad2132b 239 Gene3D G3DSA:3.40.50.2300 20 172 4.7E-41 T 06-07-2017 SMD11_RS21350 c83e6e8bc60a22612552e9aafad2132b 239 Pfam PF00196 Bacterial regulatory proteins, luxR family 173 226 1.3E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 SUPERFAMILY SSF50249 32 133 1.49E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 Gene3D G3DSA:2.40.50.140 116 192 8.0E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 Gene3D G3DSA:2.40.50.140 30 109 3.1E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 SUPERFAMILY SSF50249 113 191 1.34E-14 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 Gene3D G3DSA:2.40.50.140 205 286 1.8E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 SUPERFAMILY SSF50249 280 368 4.08E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 Pfam PF00575 S1 RNA binding domain 36 108 1.3E-15 T 06-07-2017 IPR003029 S1 domain GO:0003676 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 Pfam PF00575 S1 RNA binding domain 124 191 1.1E-13 T 06-07-2017 IPR003029 S1 domain GO:0003676 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 Pfam PF00575 S1 RNA binding domain 294 366 3.6E-23 T 06-07-2017 IPR003029 S1 domain GO:0003676 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 Pfam PF00575 S1 RNA binding domain 209 280 9.6E-26 T 06-07-2017 IPR003029 S1 domain GO:0003676 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 Gene3D G3DSA:2.40.50.140 287 369 1.9E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 SMART SM00316 37 108 4.2E-17 T 06-07-2017 IPR022967 RNA-binding domain, S1 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 SMART SM00316 210 280 1.3E-27 T 06-07-2017 IPR022967 RNA-binding domain, S1 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 SMART SM00316 124 191 6.5E-11 T 06-07-2017 IPR022967 RNA-binding domain, S1 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 SMART SM00316 295 366 1.1E-26 T 06-07-2017 IPR022967 RNA-binding domain, S1 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 SUPERFAMILY SSF50249 210 292 3.29E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 PRINTS PR00681 Ribosomal protein S1 signature 175 195 4.1E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 PRINTS PR00681 Ribosomal protein S1 signature 146 163 4.1E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 PRINTS PR00681 Ribosomal protein S1 signature 310 329 4.1E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 PRINTS PR00681 Ribosomal protein S1 signature 232 253 4.1E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 PRINTS PR00681 Ribosomal protein S1 signature 105 124 4.1E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 PRINTS PR00681 Ribosomal protein S1 signature 349 367 4.1E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 PRINTS PR00681 Ribosomal protein S1 signature 57 71 4.1E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 PRINTS PR00681 Ribosomal protein S1 signature 39 57 4.1E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SMD11_RS24975 117f175d180c8a3a01e2dbebf4bef9cc 501 PRINTS PR00681 Ribosomal protein S1 signature 129 145 4.1E-86 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SMD11_RS30880 2d6f224ace8aef03ad5eaeb85433e74c 335 SUPERFAMILY SSF81296 28 207 4.9E-49 T 06-07-2017 IPR014756 Immunoglobulin E-set SMD11_RS30880 2d6f224ace8aef03ad5eaeb85433e74c 335 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 28 204 2.1E-42 T 06-07-2017 IPR004302 Chitin-binding protein, N-terminal SMD11_RS30880 2d6f224ace8aef03ad5eaeb85433e74c 335 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 295 329 1.4E-4 T 06-07-2017 IPR019931 LPXTG cell wall anchor domain SMD11_RS30880 2d6f224ace8aef03ad5eaeb85433e74c 335 Gene3D G3DSA:2.70.50.50 28 207 2.4E-52 T 06-07-2017 SMD11_RS20525 2c64d633391909b769ec07e16e0740b3 118 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 8.0E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS20525 2c64d633391909b769ec07e16e0740b3 118 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 8.0E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS20525 2c64d633391909b769ec07e16e0740b3 118 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 8.0E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS20525 2c64d633391909b769ec07e16e0740b3 118 SUPERFAMILY SSF46955 1 114 6.96E-26 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS20525 2c64d633391909b769ec07e16e0740b3 118 SMART SM00422 1 69 1.1E-19 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS20525 2c64d633391909b769ec07e16e0740b3 118 Pfam PF13411 MerR HTH family regulatory protein 1 67 7.1E-17 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS20525 2c64d633391909b769ec07e16e0740b3 118 Gene3D G3DSA:1.10.1660.10 1 115 2.5E-29 T 06-07-2017 SMD11_RS20525 2c64d633391909b769ec07e16e0740b3 118 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS05565 e8b8f1fa3ff17d0d569731b73a5a423a 319 Gene3D G3DSA:3.30.530.20 11 121 2.0E-14 T 06-07-2017 IPR023393 START-like domain SMD11_RS05565 e8b8f1fa3ff17d0d569731b73a5a423a 319 SUPERFAMILY SSF55961 163 309 1.36E-19 T 06-07-2017 SMD11_RS05565 e8b8f1fa3ff17d0d569731b73a5a423a 319 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 163 300 7.8E-8 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase SMD11_RS05565 e8b8f1fa3ff17d0d569731b73a5a423a 319 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 18 123 4.1E-11 T 06-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain SMD11_RS05565 e8b8f1fa3ff17d0d569731b73a5a423a 319 SUPERFAMILY SSF55961 10 154 1.79E-31 T 06-07-2017 SMD11_RS31900 bfb7b5ff9c000bbcdd7e9eeb867dcd46 494 ProSitePatterns PS00218 Amino acid permeases signature. 65 95 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD11_RS31900 bfb7b5ff9c000bbcdd7e9eeb867dcd46 494 PIRSF PIRSF006060 19 494 3.4E-60 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS31900 bfb7b5ff9c000bbcdd7e9eeb867dcd46 494 Pfam PF00324 Amino acid permease 40 480 9.0E-104 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMD11_RS01130 0654042a2e834f5a5c47a965b68fe660 428 Gene3D G3DSA:3.40.50.2000 197 360 2.8E-24 T 06-07-2017 SMD11_RS01130 0654042a2e834f5a5c47a965b68fe660 428 SUPERFAMILY SSF53756 79 381 2.96E-66 T 06-07-2017 SMD11_RS01130 0654042a2e834f5a5c47a965b68fe660 428 SUPERFAMILY SSF53756 2 45 2.96E-66 T 06-07-2017 SMD11_RS01130 0654042a2e834f5a5c47a965b68fe660 428 Pfam PF00534 Glycosyl transferases group 1 198 358 3.7E-34 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 SMD11_RS01290 9c221f161418c2c04170932246e3386d 419 SMART SM00421 355 412 4.3E-4 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS01290 9c221f161418c2c04170932246e3386d 419 Gene3D G3DSA:1.10.10.10 364 417 2.4E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01290 9c221f161418c2c04170932246e3386d 419 SUPERFAMILY SSF46894 357 418 2.58E-9 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS01290 9c221f161418c2c04170932246e3386d 419 Pfam PF00196 Bacterial regulatory proteins, luxR family 363 408 4.9E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS25405 959f1be09af1145ca5f1a0ea93c12578 218 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 13 184 9.0E-45 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal SMD11_RS25405 959f1be09af1145ca5f1a0ea93c12578 218 SUPERFAMILY SSF53639 7 215 2.16E-59 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal SMD11_RS25405 959f1be09af1145ca5f1a0ea93c12578 218 SMART SM01007 12 185 2.0E-59 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal SMD11_RS25405 959f1be09af1145ca5f1a0ea93c12578 218 Gene3D G3DSA:3.40.225.10 8 215 7.2E-65 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal SMD11_RS28780 ac0c97b824b5e7657779bf196e4b21c8 389 Pfam PF00155 Aminotransferase class I and II 36 380 6.8E-53 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS28780 ac0c97b824b5e7657779bf196e4b21c8 389 Gene3D G3DSA:3.90.1150.10 274 384 1.8E-12 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS28780 ac0c97b824b5e7657779bf196e4b21c8 389 SUPERFAMILY SSF53383 9 384 6.72E-90 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS28780 ac0c97b824b5e7657779bf196e4b21c8 389 Gene3D G3DSA:3.40.640.10 54 273 1.9E-76 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS28780 ac0c97b824b5e7657779bf196e4b21c8 389 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 237 246 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMD11_RS27250 d919a30bbfe499ad86455febd3177f91 237 Pfam PF10615 Protein of unknown function (DUF2470) 147 228 4.8E-5 T 06-07-2017 IPR019595 Domain of unknown function DUF2470 SMD11_RS27250 d919a30bbfe499ad86455febd3177f91 237 SUPERFAMILY SSF50475 94 235 6.67E-12 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS27250 d919a30bbfe499ad86455febd3177f91 237 Gene3D G3DSA:3.20.180.10 141 235 3.0E-6 T 06-07-2017 IPR019595 Domain of unknown function DUF2470 SMD11_RS20370 412e7d7b1bb050dd52e115783f60553c 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.1E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20370 412e7d7b1bb050dd52e115783f60553c 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.1E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20370 412e7d7b1bb050dd52e115783f60553c 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 25 42 1.1E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20370 412e7d7b1bb050dd52e115783f60553c 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.1E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20370 412e7d7b1bb050dd52e115783f60553c 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 1.1E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20370 412e7d7b1bb050dd52e115783f60553c 231 Gene3D G3DSA:3.40.50.720 25 198 3.5E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20370 412e7d7b1bb050dd52e115783f60553c 231 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS20370 412e7d7b1bb050dd52e115783f60553c 231 SUPERFAMILY SSF51735 24 201 1.3E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20370 412e7d7b1bb050dd52e115783f60553c 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 7.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20370 412e7d7b1bb050dd52e115783f60553c 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 7.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20370 412e7d7b1bb050dd52e115783f60553c 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 7.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS20370 412e7d7b1bb050dd52e115783f60553c 231 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 30 199 5.7E-46 T 06-07-2017 SMD11_RS09780 9277cbc64f8f1e9677ff1f5066b221c2 217 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 5 200 6.5E-48 T 06-07-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 SMD11_RS09780 9277cbc64f8f1e9677ff1f5066b221c2 217 Gene3D G3DSA:3.90.550.10 5 173 1.4E-21 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS09780 9277cbc64f8f1e9677ff1f5066b221c2 217 Pfam PF01983 Guanylyl transferase CofC like 5 196 5.8E-8 T 06-07-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 SMD11_RS09780 9277cbc64f8f1e9677ff1f5066b221c2 217 SUPERFAMILY SSF53448 3 202 2.88E-28 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS09780 9277cbc64f8f1e9677ff1f5066b221c2 217 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 3 208 21.679 T 06-07-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 SMD11_RS00835 09befefdd3d26db355f2529a55cc82d2 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 348 357 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS00835 09befefdd3d26db355f2529a55cc82d2 407 PRINTS PR00359 B-class P450 signature 325 340 6.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00835 09befefdd3d26db355f2529a55cc82d2 407 PRINTS PR00359 B-class P450 signature 355 366 6.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00835 09befefdd3d26db355f2529a55cc82d2 407 PRINTS PR00359 B-class P450 signature 141 157 6.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00835 09befefdd3d26db355f2529a55cc82d2 407 PRINTS PR00359 B-class P450 signature 158 173 6.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00835 09befefdd3d26db355f2529a55cc82d2 407 PRINTS PR00359 B-class P450 signature 94 105 6.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00835 09befefdd3d26db355f2529a55cc82d2 407 PRINTS PR00359 B-class P450 signature 346 355 6.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00835 09befefdd3d26db355f2529a55cc82d2 407 PRINTS PR00359 B-class P450 signature 278 289 6.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00835 09befefdd3d26db355f2529a55cc82d2 407 PRINTS PR00359 B-class P450 signature 297 324 6.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00835 09befefdd3d26db355f2529a55cc82d2 407 PRINTS PR00359 B-class P450 signature 196 218 6.8E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00835 09befefdd3d26db355f2529a55cc82d2 407 Pfam PF00067 Cytochrome P450 276 373 1.0E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00835 09befefdd3d26db355f2529a55cc82d2 407 Gene3D G3DSA:1.10.630.10 14 403 6.2E-101 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00835 09befefdd3d26db355f2529a55cc82d2 407 SUPERFAMILY SSF48264 26 402 7.2E-76 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS09330 bdd6f2eed2c38a3f9c8922d0fe22b777 452 Gene3D G3DSA:3.40.640.10 81 329 5.9E-78 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS09330 bdd6f2eed2c38a3f9c8922d0fe22b777 452 SUPERFAMILY SSF53383 40 450 3.52E-122 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS09330 bdd6f2eed2c38a3f9c8922d0fe22b777 452 Pfam PF00202 Aminotransferase class-III 42 448 2.0E-117 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS09330 bdd6f2eed2c38a3f9c8922d0fe22b777 452 Gene3D G3DSA:3.90.1150.10 330 451 9.0E-39 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS09330 bdd6f2eed2c38a3f9c8922d0fe22b777 452 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 31 449 3.7E-180 T 06-07-2017 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 SMD11_RS09330 bdd6f2eed2c38a3f9c8922d0fe22b777 452 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 262 299 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS07320 ec274d9ddbb340dc07cdf908a5e39809 465 SUPERFAMILY SSF51984 10 98 1.28E-26 T 06-07-2017 SMD11_RS07320 ec274d9ddbb340dc07cdf908a5e39809 465 SUPERFAMILY SSF53244 316 462 1.68E-41 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS07320 ec274d9ddbb340dc07cdf908a5e39809 465 Pfam PF01225 Mur ligase family, catalytic domain 13 109 1.2E-27 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SMD11_RS07320 ec274d9ddbb340dc07cdf908a5e39809 465 Gene3D G3DSA:3.40.1190.10 99 318 5.9E-73 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS07320 ec274d9ddbb340dc07cdf908a5e39809 465 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 13 458 3.5E-140 T 06-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS07320 ec274d9ddbb340dc07cdf908a5e39809 465 Gene3D G3DSA:3.90.190.20 319 464 2.9E-48 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS07320 ec274d9ddbb340dc07cdf908a5e39809 465 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 405 2.9E-20 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SMD11_RS07320 ec274d9ddbb340dc07cdf908a5e39809 465 Gene3D G3DSA:3.40.50.720 12 98 9.6E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS07320 ec274d9ddbb340dc07cdf908a5e39809 465 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 9 465 38.646 T 06-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS07320 ec274d9ddbb340dc07cdf908a5e39809 465 Pfam PF08245 Mur ligase middle domain 115 296 1.1E-22 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS07320 ec274d9ddbb340dc07cdf908a5e39809 465 SUPERFAMILY SSF53623 96 314 3.21E-56 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS21470 d1caba737c93a57f8a06bd5e340042f7 269 Pfam PF00392 Bacterial regulatory proteins, gntR family 39 91 1.8E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS21470 d1caba737c93a57f8a06bd5e340042f7 269 Gene3D G3DSA:1.10.10.10 26 91 8.0E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21470 d1caba737c93a57f8a06bd5e340042f7 269 Gene3D G3DSA:3.40.1410.10 92 257 1.7E-44 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS21470 d1caba737c93a57f8a06bd5e340042f7 269 SUPERFAMILY SSF46785 26 100 3.11E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21470 d1caba737c93a57f8a06bd5e340042f7 269 SMART SM00866 111 251 2.1E-34 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS21470 d1caba737c93a57f8a06bd5e340042f7 269 SUPERFAMILY SSF64288 83 257 3.77E-44 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SMD11_RS21470 d1caba737c93a57f8a06bd5e340042f7 269 SMART SM00345 35 91 3.7E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS21470 d1caba737c93a57f8a06bd5e340042f7 269 Pfam PF07702 UTRA domain 112 250 8.2E-33 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SMD11_RS21470 d1caba737c93a57f8a06bd5e340042f7 269 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 66 1.7E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS21470 d1caba737c93a57f8a06bd5e340042f7 269 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 66 82 1.7E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS27045 6e62cd092364b8cf9e456e6a57e3cc1b 349 Pfam PF00425 chorismate binding enzyme 73 329 6.4E-69 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal SMD11_RS27045 6e62cd092364b8cf9e456e6a57e3cc1b 349 Gene3D G3DSA:3.60.120.10 59 337 7.8E-98 T 06-07-2017 IPR005801 ADC synthase GO:0009058 SMD11_RS27045 6e62cd092364b8cf9e456e6a57e3cc1b 349 SUPERFAMILY SSF56322 40 336 6.15E-88 T 06-07-2017 IPR005801 ADC synthase GO:0009058 SMD11_RS27045 6e62cd092364b8cf9e456e6a57e3cc1b 349 PRINTS PR00095 Anthranilate synthase component I signature 265 279 7.6E-11 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD11_RS27045 6e62cd092364b8cf9e456e6a57e3cc1b 349 PRINTS PR00095 Anthranilate synthase component I signature 281 295 7.6E-11 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD11_RS27045 6e62cd092364b8cf9e456e6a57e3cc1b 349 PRINTS PR00095 Anthranilate synthase component I signature 185 198 7.6E-11 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD11_RS22850 a10b27dcfe2d41b48b14b243440454a3 225 PRINTS PR01218 Pistil-specific extensin-like signature 36 54 7.1E-5 T 06-07-2017 IPR003882 Pistil-specific extensin-like protein GO:0005199 SMD11_RS22850 a10b27dcfe2d41b48b14b243440454a3 225 PRINTS PR01218 Pistil-specific extensin-like signature 87 108 7.1E-5 T 06-07-2017 IPR003882 Pistil-specific extensin-like protein GO:0005199 SMD11_RS22850 a10b27dcfe2d41b48b14b243440454a3 225 PRINTS PR01218 Pistil-specific extensin-like signature 1 24 7.1E-5 T 06-07-2017 IPR003882 Pistil-specific extensin-like protein GO:0005199 SMD11_RS09270 cd64bcba984d20015935e303221b78cd 313 Gene3D G3DSA:3.90.1200.10 132 286 7.3E-6 T 06-07-2017 SMD11_RS09270 cd64bcba984d20015935e303221b78cd 313 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 44 293 1.3E-50 T 06-07-2017 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 SMD11_RS09270 cd64bcba984d20015935e303221b78cd 313 SUPERFAMILY SSF56112 36 292 1.05E-17 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS34045 baa33a7d3e440f2d73d57fb479c7c9d3 337 Gene3D G3DSA:1.10.600.10 19 320 8.1E-57 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS34045 baa33a7d3e440f2d73d57fb479c7c9d3 337 SUPERFAMILY SSF48576 22 325 3.74E-44 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 316 364 4.1E-7 T 06-07-2017 SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 SUPERFAMILY SSF55890 318 366 3.53E-7 T 06-07-2017 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 SUPERFAMILY SSF55785 218 290 6.77E-9 T 06-07-2017 IPR000014 PAS domain SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 SUPERFAMILY SSF103190 39 169 2.51E-30 T 06-07-2017 IPR029151 Periplasmic sensor domain-like SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 SMART SM00091 215 280 1.5E-5 T 06-07-2017 IPR000014 PAS domain SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 SMART SM00387 413 531 1.1E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 SUPERFAMILY SSF55874 384 529 5.89E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 Gene3D G3DSA:3.30.565.10 383 530 6.8E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 Gene3D G3DSA:1.10.287.130 305 368 1.5E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 Pfam PF00989 PAS fold 216 263 3.2E-7 T 06-07-2017 IPR013767 PAS fold GO:0006355 SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 Pfam PF17203 Single cache domain 3 38 169 4.2E-24 T 06-07-2017 IPR033463 Single cache domain 3 SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 Gene3D G3DSA:3.30.450.20 217 267 1.9E-8 T 06-07-2017 SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 528 1.9E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 509 1.9E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 472 1.9E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 Gene3D G3DSA:3.30.450.20 37 170 7.2E-41 T 06-07-2017 SMD11_RS08685 b2eb90626807f919a6fa75c1b6a44dbf 539 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 414 530 6.9E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS26565 7849dd5bf1b9efc84fd32ab7f2e3de5d 320 PIRSF PIRSF016838 2 320 1.5E-84 T 06-07-2017 IPR028349 Protein PafC SMD11_RS26565 7849dd5bf1b9efc84fd32ab7f2e3de5d 320 Pfam PF13280 WYL domain 148 315 7.8E-31 T 06-07-2017 IPR026881 WYL domain SMD11_RS32505 a0f66e1518ec595cd92f5ef6053e8069 272 Pfam PF12697 Alpha/beta hydrolase family 12 260 1.1E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS32505 a0f66e1518ec595cd92f5ef6053e8069 272 SUPERFAMILY SSF53474 4 269 1.94E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32505 a0f66e1518ec595cd92f5ef6053e8069 272 Gene3D G3DSA:3.40.50.1820 5 267 2.4E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS03015 b5070b85a84afd4a908b7d44e9b8f626 264 PRINTS PR00474 Glutamate 5-kinase family signature 204 224 9.7E-9 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 SMD11_RS03015 b5070b85a84afd4a908b7d44e9b8f626 264 PRINTS PR00474 Glutamate 5-kinase family signature 153 180 9.7E-9 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 SMD11_RS03015 b5070b85a84afd4a908b7d44e9b8f626 264 PRINTS PR00474 Glutamate 5-kinase family signature 21 35 9.7E-9 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 SMD11_RS03015 b5070b85a84afd4a908b7d44e9b8f626 264 Hamap MF_00082_B Acetylglutamate kinase [argB]. 1 254 30.164 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS03015 b5070b85a84afd4a908b7d44e9b8f626 264 SUPERFAMILY SSF53633 1 255 1.96E-73 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS03015 b5070b85a84afd4a908b7d44e9b8f626 264 Gene3D G3DSA:3.40.1160.10 1 253 4.5E-90 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS03015 b5070b85a84afd4a908b7d44e9b8f626 264 Pfam PF00696 Amino acid kinase family 8 229 2.2E-43 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase SMD11_RS03015 b5070b85a84afd4a908b7d44e9b8f626 264 PIRSF PIRSF000728 1 254 1.6E-86 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS03015 b5070b85a84afd4a908b7d44e9b8f626 264 TIGRFAM TIGR00761 argB: acetylglutamate kinase 5 228 2.8E-68 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SMD11_RS20165 81e13e0bb4df8bfa8fe04e8d991c9b5b 191 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 89 6.0E-32 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMD11_RS20165 81e13e0bb4df8bfa8fe04e8d991c9b5b 191 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 8 176 7.4E-44 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMD11_RS20165 81e13e0bb4df8bfa8fe04e8d991c9b5b 191 Gene3D G3DSA:2.40.240.10 3 92 1.6E-27 T 06-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMD11_RS20165 81e13e0bb4df8bfa8fe04e8d991c9b5b 191 Pfam PF01386 Ribosomal L25p family 8 90 4.3E-23 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMD11_RS20165 81e13e0bb4df8bfa8fe04e8d991c9b5b 191 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 177 6.1E-19 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain SMD11_RS20165 81e13e0bb4df8bfa8fe04e8d991c9b5b 191 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 179 25.502 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 SMD11_RS20165 81e13e0bb4df8bfa8fe04e8d991c9b5b 191 SUPERFAMILY SSF50715 4 184 3.66E-49 T 06-07-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMD11_RS20165 81e13e0bb4df8bfa8fe04e8d991c9b5b 191 Gene3D G3DSA:2.170.120.20 95 184 3.5E-21 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain SMD11_RS32565 e9b39085bf39393a98291f69835a06c9 468 Pfam PF01425 Amidase 26 444 2.8E-97 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS32565 e9b39085bf39393a98291f69835a06c9 468 SUPERFAMILY SSF75304 5 453 1.3E-123 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS32565 e9b39085bf39393a98291f69835a06c9 468 Gene3D G3DSA:3.90.1300.10 3 458 1.7E-122 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS32565 e9b39085bf39393a98291f69835a06c9 468 ProSitePatterns PS00571 Amidases signature. 158 189 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMD11_RS11450 3ce2ba586df670b7ea896c913766f702 231 SUPERFAMILY SSF46689 4 74 1.45E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS11450 3ce2ba586df670b7ea896c913766f702 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 1.4E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS11450 3ce2ba586df670b7ea896c913766f702 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 8.8E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS11450 3ce2ba586df670b7ea896c913766f702 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 8.8E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS11450 3ce2ba586df670b7ea896c913766f702 231 Gene3D G3DSA:1.10.357.10 3 222 3.3E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS08070 cdbbccae7c2b1e10a743a0b02e72a0be 402 Gene3D G3DSA:1.10.630.10 9 401 1.4E-109 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS08070 cdbbccae7c2b1e10a743a0b02e72a0be 402 SUPERFAMILY SSF48264 19 401 7.99E-91 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS08070 cdbbccae7c2b1e10a743a0b02e72a0be 402 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS08070 cdbbccae7c2b1e10a743a0b02e72a0be 402 Pfam PF00067 Cytochrome P450 87 370 8.3E-30 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS08070 cdbbccae7c2b1e10a743a0b02e72a0be 402 PRINTS PR00359 B-class P450 signature 149 164 1.2E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08070 cdbbccae7c2b1e10a743a0b02e72a0be 402 PRINTS PR00359 B-class P450 signature 342 351 1.2E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08070 cdbbccae7c2b1e10a743a0b02e72a0be 402 PRINTS PR00359 B-class P450 signature 132 148 1.2E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08070 cdbbccae7c2b1e10a743a0b02e72a0be 402 PRINTS PR00359 B-class P450 signature 195 217 1.2E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08070 cdbbccae7c2b1e10a743a0b02e72a0be 402 PRINTS PR00359 B-class P450 signature 276 287 1.2E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08070 cdbbccae7c2b1e10a743a0b02e72a0be 402 PRINTS PR00359 B-class P450 signature 321 336 1.2E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08070 cdbbccae7c2b1e10a743a0b02e72a0be 402 PRINTS PR00359 B-class P450 signature 351 362 1.2E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08070 cdbbccae7c2b1e10a743a0b02e72a0be 402 PRINTS PR00359 B-class P450 signature 86 97 1.2E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08070 cdbbccae7c2b1e10a743a0b02e72a0be 402 PRINTS PR00359 B-class P450 signature 293 320 1.2E-55 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS24860 c5d944c6885d934f88485c8cb66bc358 101 SUPERFAMILY SSF48600 8 97 5.95E-25 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD11_RS24860 c5d944c6885d934f88485c8cb66bc358 101 Pfam PF01817 Chorismate mutase type II 18 93 1.4E-17 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD11_RS24860 c5d944c6885d934f88485c8cb66bc358 101 Gene3D G3DSA:1.20.59.10 4 96 8.0E-21 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD11_RS24860 c5d944c6885d934f88485c8cb66bc358 101 SMART SM00830 18 98 2.5E-21 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD11_RS24860 c5d944c6885d934f88485c8cb66bc358 101 TIGRFAM TIGR01795 CM_mono_cladeE: chorismate mutase 10 100 7.2E-49 T 06-07-2017 IPR010951 Chorismate mutase, bacteria SMD11_RS19295 55259ad2acf2d65c19349d77e685655e 419 Pfam PF00069 Protein kinase domain 19 265 1.4E-43 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS19295 55259ad2acf2d65c19349d77e685655e 419 Gene3D G3DSA:3.30.200.20 11 88 5.4E-22 T 06-07-2017 SMD11_RS19295 55259ad2acf2d65c19349d77e685655e 419 Gene3D G3DSA:1.10.510.10 89 274 3.7E-43 T 06-07-2017 SMD11_RS19295 55259ad2acf2d65c19349d77e685655e 419 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 142 154 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS19295 55259ad2acf2d65c19349d77e685655e 419 SUPERFAMILY SSF56112 16 316 1.01E-66 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS19295 55259ad2acf2d65c19349d77e685655e 419 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 25 48 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS19295 55259ad2acf2d65c19349d77e685655e 419 SMART SM00220 19 273 2.9E-51 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS17755 f582670d756d4d1757ae176e770db672 291 Pfam PF03301 Tryptophan 2,3-dioxygenase 26 289 4.7E-65 T 06-07-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 SMD11_RS17755 f582670d756d4d1757ae176e770db672 291 SUPERFAMILY SSF140959 35 289 3.4E-77 T 06-07-2017 SMD11_RS17755 f582670d756d4d1757ae176e770db672 291 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 29 291 35.683 T 06-07-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 SMD11_RS14925 1ef313336afe9bb4d933a09dec1e72d9 119 Gene3D G3DSA:3.30.1130.10 2 118 1.2E-45 T 06-07-2017 SMD11_RS14925 1ef313336afe9bb4d933a09dec1e72d9 119 TIGRFAM TIGR00526 folB_dom: FolB domain 2 118 8.7E-32 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD11_RS14925 1ef313336afe9bb4d933a09dec1e72d9 119 SMART SM00905 4 116 1.4E-48 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD11_RS14925 1ef313336afe9bb4d933a09dec1e72d9 119 Pfam PF02152 Dihydroneopterin aldolase 5 115 2.2E-35 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD11_RS14925 1ef313336afe9bb4d933a09dec1e72d9 119 SUPERFAMILY SSF55620 2 118 1.45E-36 T 06-07-2017 SMD11_RS14925 1ef313336afe9bb4d933a09dec1e72d9 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 116 2.2E-36 T 06-07-2017 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SMD11_RS03715 17370afb31bac748f268ebfe1f2ce233 386 Gene3D G3DSA:1.20.140.10 242 379 5.6E-36 T 06-07-2017 SMD11_RS03715 17370afb31bac748f268ebfe1f2ce233 386 SUPERFAMILY SSF56645 14 211 4.65E-20 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS03715 17370afb31bac748f268ebfe1f2ce233 386 Gene3D G3DSA:1.10.540.10 18 113 4.8E-13 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS03715 17370afb31bac748f268ebfe1f2ce233 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 377 6.6E-28 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS03715 17370afb31bac748f268ebfe1f2ce233 386 SUPERFAMILY SSF47203 243 378 1.93E-35 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS03715 17370afb31bac748f268ebfe1f2ce233 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 105 5.1E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS23235 72faef5c89fb12d4fc279838a2afa33b 437 Gene3D G3DSA:3.30.565.10 340 433 8.4E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS23235 72faef5c89fb12d4fc279838a2afa33b 437 SUPERFAMILY SSF55874 314 429 5.09E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS23235 72faef5c89fb12d4fc279838a2afa33b 437 Pfam PF07730 Histidine kinase 219 284 1.3E-20 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS33080 e5ea07e37956043a316bcbce5f3e3fc0 277 Pfam PF00455 DeoR C terminal sensor domain 99 257 6.3E-38 T 06-07-2017 IPR014036 DeoR C-terminal sensor domain SMD11_RS33080 e5ea07e37956043a316bcbce5f3e3fc0 277 SMART SM00420 30 82 3.0E-13 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS33080 e5ea07e37956043a316bcbce5f3e3fc0 277 SUPERFAMILY SSF46785 27 86 6.83E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33080 e5ea07e37956043a316bcbce5f3e3fc0 277 Gene3D G3DSA:3.40.50.1360 100 224 3.9E-5 T 06-07-2017 SMD11_RS33080 e5ea07e37956043a316bcbce5f3e3fc0 277 Pfam PF08220 DeoR-like helix-turn-helix domain 30 82 1.9E-15 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS33080 e5ea07e37956043a316bcbce5f3e3fc0 277 SMART SM01134 97 258 4.9E-48 T 06-07-2017 SMD11_RS33080 e5ea07e37956043a316bcbce5f3e3fc0 277 Gene3D G3DSA:1.10.10.10 24 80 1.6E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33080 e5ea07e37956043a316bcbce5f3e3fc0 277 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 62 80 7.1E-10 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS33080 e5ea07e37956043a316bcbce5f3e3fc0 277 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 48 62 7.1E-10 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS33080 e5ea07e37956043a316bcbce5f3e3fc0 277 SUPERFAMILY SSF100950 99 260 2.72E-19 T 06-07-2017 SMD11_RS08025 a3319cefc92d9deaf45e527f2e5a4085 407 TIGRFAM TIGR04515 P450_rel_GT_act: P450-derived glycosyltranferase activator 13 406 6.1E-109 T 06-07-2017 IPR030958 P450-derived glycosyltranferase activator SMD11_RS08025 a3319cefc92d9deaf45e527f2e5a4085 407 Gene3D G3DSA:1.10.630.10 41 406 1.9E-36 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS08025 a3319cefc92d9deaf45e527f2e5a4085 407 PRINTS PR00359 B-class P450 signature 173 188 3.1E-8 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08025 a3319cefc92d9deaf45e527f2e5a4085 407 PRINTS PR00359 B-class P450 signature 297 308 3.1E-8 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08025 a3319cefc92d9deaf45e527f2e5a4085 407 PRINTS PR00359 B-class P450 signature 156 172 3.1E-8 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08025 a3319cefc92d9deaf45e527f2e5a4085 407 PRINTS PR00359 B-class P450 signature 314 341 3.1E-8 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08025 a3319cefc92d9deaf45e527f2e5a4085 407 SUPERFAMILY SSF48264 46 406 6.55E-30 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS11455 e7abbf5705be63687702be43a1536aa9 264 Pfam PF00459 Inositol monophosphatase family 10 261 2.2E-45 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS11455 e7abbf5705be63687702be43a1536aa9 264 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site SMD11_RS11455 e7abbf5705be63687702be43a1536aa9 264 SUPERFAMILY SSF56655 3 263 7.98E-74 T 06-07-2017 SMD11_RS11455 e7abbf5705be63687702be43a1536aa9 264 Gene3D G3DSA:3.40.190.80 159 263 1.3E-22 T 06-07-2017 SMD11_RS11455 e7abbf5705be63687702be43a1536aa9 264 Gene3D G3DSA:3.30.540.10 3 158 1.2E-43 T 06-07-2017 SMD11_RS11455 e7abbf5705be63687702be43a1536aa9 264 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 8 263 3.8E-89 T 06-07-2017 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 SMD11_RS11455 e7abbf5705be63687702be43a1536aa9 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 7.1E-12 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS11455 e7abbf5705be63687702be43a1536aa9 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 7.1E-12 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS11455 e7abbf5705be63687702be43a1536aa9 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 7.1E-12 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS10080 ef0eeae82cadeccca13887b08d67756f 320 Gene3D G3DSA:3.40.50.720 115 286 1.4E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10080 ef0eeae82cadeccca13887b08d67756f 320 Gene3D G3DSA:3.40.50.720 66 114 7.3E-5 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10080 ef0eeae82cadeccca13887b08d67756f 320 SUPERFAMILY SSF51735 105 286 8.41E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10080 ef0eeae82cadeccca13887b08d67756f 320 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 285 7.5E-47 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SMD11_RS10080 ef0eeae82cadeccca13887b08d67756f 320 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 225 241 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SMD11_RS20625 4db3fd972b0c583e9c2ad1cdc8f609ce 500 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 104 256 1.3E-46 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS20625 4db3fd972b0c583e9c2ad1cdc8f609ce 500 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 104 257 1.7E-46 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS20625 4db3fd972b0c583e9c2ad1cdc8f609ce 500 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 376 462 1.2E-12 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMD11_RS01700 2242783b1ce3d1412632b96d14b04c2d 310 SUPERFAMILY SSF54593 4 288 4.96E-37 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS01700 2242783b1ce3d1412632b96d14b04c2d 310 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 118 2.4E-4 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS01700 2242783b1ce3d1412632b96d14b04c2d 310 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 140 254 7.8E-15 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS01700 2242783b1ce3d1412632b96d14b04c2d 310 Gene3D G3DSA:3.10.180.10 5 120 1.5E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS01700 2242783b1ce3d1412632b96d14b04c2d 310 Gene3D G3DSA:3.10.180.10 139 272 1.2E-33 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS26200 8d28a495c3ec590eeb1b48cc814833f8 365 Gene3D G3DSA:3.40.50.720 187 226 1.2E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS26200 8d28a495c3ec590eeb1b48cc814833f8 365 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SMD11_RS26200 8d28a495c3ec590eeb1b48cc814833f8 365 SUPERFAMILY SSF51735 176 228 1.15E-8 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS26200 8d28a495c3ec590eeb1b48cc814833f8 365 SUPERFAMILY SSF50129 2 186 3.25E-50 T 06-07-2017 IPR011032 GroES-like SMD11_RS26200 8d28a495c3ec590eeb1b48cc814833f8 365 SMART SM00829 11 362 1.6E-4 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS26200 8d28a495c3ec590eeb1b48cc814833f8 365 Gene3D G3DSA:3.90.180.10 2 186 4.8E-55 T 06-07-2017 IPR011032 GroES-like SMD11_RS26200 8d28a495c3ec590eeb1b48cc814833f8 365 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 113 1.8E-22 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS33860 e13e4a761b66fa9bb7f648ff17ade95c 259 SMART SM01134 77 237 2.6E-53 T 06-07-2017 SMD11_RS33860 e13e4a761b66fa9bb7f648ff17ade95c 259 ProSitePatterns PS00894 DeoR-type HTH domain signature. 10 44 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMD11_RS33860 e13e4a761b66fa9bb7f648ff17ade95c 259 Pfam PF00455 DeoR C terminal sensor domain 80 235 2.1E-43 T 06-07-2017 IPR014036 DeoR C-terminal sensor domain SMD11_RS33860 e13e4a761b66fa9bb7f648ff17ade95c 259 SUPERFAMILY SSF46785 8 71 2.6E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33860 e13e4a761b66fa9bb7f648ff17ade95c 259 Gene3D G3DSA:3.40.50.1360 79 218 4.3E-6 T 06-07-2017 SMD11_RS33860 e13e4a761b66fa9bb7f648ff17ade95c 259 SMART SM00420 10 62 1.2E-11 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS33860 e13e4a761b66fa9bb7f648ff17ade95c 259 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 28 42 9.4E-6 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS33860 e13e4a761b66fa9bb7f648ff17ade95c 259 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 42 60 9.4E-6 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS33860 e13e4a761b66fa9bb7f648ff17ade95c 259 SUPERFAMILY SSF100950 79 236 2.41E-21 T 06-07-2017 SMD11_RS33860 e13e4a761b66fa9bb7f648ff17ade95c 259 Gene3D G3DSA:1.10.10.10 7 59 8.5E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33860 e13e4a761b66fa9bb7f648ff17ade95c 259 Pfam PF08220 DeoR-like helix-turn-helix domain 10 63 1.4E-13 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS25235 dabc3b597d7f3b9e3d4fa1e9a89cfe3a 151 Gene3D G3DSA:3.90.1010.10 5 147 8.4E-45 T 06-07-2017 SMD11_RS25235 dabc3b597d7f3b9e3d4fa1e9a89cfe3a 151 Pfam PF01592 NifU-like N terminal domain 6 129 2.6E-26 T 06-07-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 SMD11_RS25235 dabc3b597d7f3b9e3d4fa1e9a89cfe3a 151 SUPERFAMILY SSF82649 2 142 6.54E-43 T 06-07-2017 SMD11_RS25235 dabc3b597d7f3b9e3d4fa1e9a89cfe3a 151 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 140 1.1E-47 T 06-07-2017 SMD11_RS03510 c18ce9b85c17aa8e23c76e2b912f45d0 309 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 35 274 7.4E-46 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SMD11_RS03510 c18ce9b85c17aa8e23c76e2b912f45d0 309 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 68 79 2.0E-14 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD11_RS03510 c18ce9b85c17aa8e23c76e2b912f45d0 309 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 155 168 2.0E-14 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD11_RS03510 c18ce9b85c17aa8e23c76e2b912f45d0 309 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 122 139 2.0E-14 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SMD11_RS03510 c18ce9b85c17aa8e23c76e2b912f45d0 309 Gene3D G3DSA:3.40.710.10 38 291 5.4E-80 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS03510 c18ce9b85c17aa8e23c76e2b912f45d0 309 SUPERFAMILY SSF56601 38 289 2.01E-60 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS23935 9d84ed63ab8e747264cc2af429acfd95 1059 Pfam PF05089 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain 159 479 3.4E-98 T 06-07-2017 IPR024733 Alpha-N-acetylglucosaminidase, tim-barrel domain KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096|Reactome: R-HSA-2206282 SMD11_RS23935 9d84ed63ab8e747264cc2af429acfd95 1059 Pfam PF12972 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain 487 751 8.9E-73 T 06-07-2017 IPR024732 Alpha-N-acetylglucosaminidase, C-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096|Reactome: R-HSA-2206282 SMD11_RS23935 9d84ed63ab8e747264cc2af429acfd95 1059 Pfam PF12971 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain 67 145 3.8E-21 T 06-07-2017 IPR024240 Alpha-N-acetylglucosaminidase, N-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096|Reactome: R-HSA-2206282 SMD11_RS26995 17c7a1ebaeb35132026b62d8dff9bce3 409 Gene3D G3DSA:3.40.50.720 9 115 6.7E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS26995 17c7a1ebaeb35132026b62d8dff9bce3 409 SUPERFAMILY SSF53790 168 402 1.96E-71 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS26995 17c7a1ebaeb35132026b62d8dff9bce3 409 Gene3D G3DSA:3.40.1010.10 169 282 2.5E-40 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS26995 17c7a1ebaeb35132026b62d8dff9bce3 409 SUPERFAMILY SSF51735 10 112 9.86E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS26995 17c7a1ebaeb35132026b62d8dff9bce3 409 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 169 403 4.7E-83 T 06-07-2017 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMD11_RS26995 17c7a1ebaeb35132026b62d8dff9bce3 409 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 169 380 1.2E-48 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS26995 17c7a1ebaeb35132026b62d8dff9bce3 409 Gene3D G3DSA:3.30.950.10 283 403 4.3E-42 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS26995 17c7a1ebaeb35132026b62d8dff9bce3 409 Pfam PF13241 Putative NAD(P)-binding 14 120 2.4E-16 T 06-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMD11_RS26995 17c7a1ebaeb35132026b62d8dff9bce3 409 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 11 135 2.7E-18 T 06-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMD11_RS26995 17c7a1ebaeb35132026b62d8dff9bce3 409 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 247 280 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 SMD11_RS20285 40f0b9f1a4418605c6794619d56c05c3 369 Pfam PF01476 LysM domain 320 365 3.4E-5 T 06-07-2017 IPR018392 LysM domain SMD11_RS20285 40f0b9f1a4418605c6794619d56c05c3 369 Gene3D G3DSA:1.10.530.10 17 122 2.8E-38 T 06-07-2017 SMD11_RS20285 40f0b9f1a4418605c6794619d56c05c3 369 SMART SM00257 319 368 5.1E-5 T 06-07-2017 IPR018392 LysM domain SMD11_RS20285 40f0b9f1a4418605c6794619d56c05c3 369 SUPERFAMILY SSF53955 41 122 3.73E-27 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS20285 40f0b9f1a4418605c6794619d56c05c3 369 Pfam PF06737 Transglycosylase-like domain 40 116 7.1E-31 T 06-07-2017 IPR010618 Transglycosylase-like SMD11_RS20285 40f0b9f1a4418605c6794619d56c05c3 369 SUPERFAMILY SSF54106 320 365 8.63E-5 T 06-07-2017 IPR018392 LysM domain SMD11_RS20285 40f0b9f1a4418605c6794619d56c05c3 369 Gene3D G3DSA:3.10.350.10 320 365 1.3E-8 T 06-07-2017 IPR018392 LysM domain SMD11_RS20285 40f0b9f1a4418605c6794619d56c05c3 369 PRINTS PR01217 Proline rich extensin signature 224 249 1.4E-9 T 06-07-2017 SMD11_RS20285 40f0b9f1a4418605c6794619d56c05c3 369 PRINTS PR01217 Proline rich extensin signature 138 159 1.4E-9 T 06-07-2017 SMD11_RS20285 40f0b9f1a4418605c6794619d56c05c3 369 PRINTS PR01217 Proline rich extensin signature 172 188 1.4E-9 T 06-07-2017 SMD11_RS20285 40f0b9f1a4418605c6794619d56c05c3 369 PRINTS PR01217 Proline rich extensin signature 192 209 1.4E-9 T 06-07-2017 SMD11_RS29025 03a7f8f728cb428c23c10bf0dba6a9b5 314 SMART SM00382 39 217 1.2E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS29025 03a7f8f728cb428c23c10bf0dba6a9b5 314 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS29025 03a7f8f728cb428c23c10bf0dba6a9b5 314 SUPERFAMILY SSF52540 10 236 6.2E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29025 03a7f8f728cb428c23c10bf0dba6a9b5 314 Pfam PF00005 ABC transporter 30 170 4.0E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS29025 03a7f8f728cb428c23c10bf0dba6a9b5 314 Gene3D G3DSA:3.40.50.300 5 237 1.4E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13975 5985b34f13d01e71a3dad8083f3b8c5d 283 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 275 4.9E-66 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMD11_RS13975 5985b34f13d01e71a3dad8083f3b8c5d 283 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 282 1.4E-76 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMD11_RS13975 5985b34f13d01e71a3dad8083f3b8c5d 283 Gene3D G3DSA:3.20.20.70 1 282 5.4E-83 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS13975 5985b34f13d01e71a3dad8083f3b8c5d 283 SUPERFAMILY SSF51569 2 282 2.2E-78 T 06-07-2017 SMD11_RS13975 5985b34f13d01e71a3dad8083f3b8c5d 283 PIRSF PIRSF001359 1 283 2.7E-68 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SMD11_RS04305 c3a5e2e13df225d780ac6512510af105 478 SUPERFAMILY SSF55124 28 110 3.11E-21 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS04305 c3a5e2e13df225d780ac6512510af105 478 Gene3D G3DSA:3.90.480.10 44 113 2.6E-26 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS04305 c3a5e2e13df225d780ac6512510af105 478 Gene3D G3DSA:3.90.480.10 286 365 2.6E-26 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS04305 c3a5e2e13df225d780ac6512510af105 478 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 49 106 1.5E-10 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS04305 c3a5e2e13df225d780ac6512510af105 478 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 299 360 3.7E-10 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS04305 c3a5e2e13df225d780ac6512510af105 478 SUPERFAMILY SSF55124 229 368 2.45E-18 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 SMD11_RS10525 5165269c3220c6b64408979e3e8d90ed 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 158 3.0E-22 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD11_RS10525 5165269c3220c6b64408979e3e8d90ed 291 SUPERFAMILY SSF51735 7 158 1.13E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10525 5165269c3220c6b64408979e3e8d90ed 291 PIRSF PIRSF000103 1 291 2.3E-34 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD11_RS10525 5165269c3220c6b64408979e3e8d90ed 291 Gene3D G3DSA:3.40.50.720 3 159 3.2E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS17425 89869207ff5a8cc7c73ad97bf825ae7c 511 Pfam PF07690 Major Facilitator Superfamily 24 414 2.7E-49 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS17425 89869207ff5a8cc7c73ad97bf825ae7c 511 SUPERFAMILY SSF103473 12 204 1.18E-58 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS17425 89869207ff5a8cc7c73ad97bf825ae7c 511 SUPERFAMILY SSF103473 252 470 1.18E-58 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS17425 89869207ff5a8cc7c73ad97bf825ae7c 511 ProSitePatterns PS00216 Sugar transport proteins signature 1. 71 88 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS17425 89869207ff5a8cc7c73ad97bf825ae7c 511 Gene3D G3DSA:1.20.1250.20 16 198 2.9E-29 T 06-07-2017 SMD11_RS17425 89869207ff5a8cc7c73ad97bf825ae7c 511 Gene3D G3DSA:1.20.1250.20 274 473 4.2E-17 T 06-07-2017 SMD11_RS14485 c18ba117bafcef29fd4fdd8f2c94e216 132 Pfam PF01638 HxlR-like helix-turn-helix 14 100 9.2E-33 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type SMD11_RS14485 c18ba117bafcef29fd4fdd8f2c94e216 132 SUPERFAMILY SSF46785 2 105 2.28E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14485 c18ba117bafcef29fd4fdd8f2c94e216 132 Gene3D G3DSA:1.10.10.10 2 109 2.7E-41 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32955 714f5d863a8ecbf79417fd15cd5aa7d3 329 SMART SM00861 21 184 4.6E-40 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS32955 714f5d863a8ecbf79417fd15cd5aa7d3 329 SUPERFAMILY SSF52518 19 183 5.4E-45 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS32955 714f5d863a8ecbf79417fd15cd5aa7d3 329 Gene3D G3DSA:3.40.50.920 195 324 2.3E-35 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS32955 714f5d863a8ecbf79417fd15cd5aa7d3 329 Pfam PF02780 Transketolase, C-terminal domain 195 316 8.5E-28 T 06-07-2017 IPR033248 Transketolase, C-terminal domain SMD11_RS32955 714f5d863a8ecbf79417fd15cd5aa7d3 329 Gene3D G3DSA:3.40.50.970 19 194 1.7E-45 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS32955 714f5d863a8ecbf79417fd15cd5aa7d3 329 Pfam PF02779 Transketolase, pyrimidine binding domain 24 181 2.8E-28 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS32955 714f5d863a8ecbf79417fd15cd5aa7d3 329 SUPERFAMILY SSF52922 191 324 5.76E-31 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS25605 efb5494690d147b4906736489e08c9d3 883 SUPERFAMILY SSF52540 313 554 7.66E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25605 efb5494690d147b4906736489e08c9d3 883 Pfam PF00498 FHA domain 234 294 3.1E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS25605 efb5494690d147b4906736489e08c9d3 883 Pfam PF00498 FHA domain 25 88 3.2E-16 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS25605 efb5494690d147b4906736489e08c9d3 883 Gene3D G3DSA:2.60.200.20 13 90 4.4E-23 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS25605 efb5494690d147b4906736489e08c9d3 883 SMART SM00382 344 538 4.6E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS25605 efb5494690d147b4906736489e08c9d3 883 SUPERFAMILY SSF49879 13 90 3.06E-22 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 SMD11_RS25605 efb5494690d147b4906736489e08c9d3 883 Gene3D G3DSA:3.40.50.300 315 545 1.6E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25605 efb5494690d147b4906736489e08c9d3 883 SMART SM00240 24 74 1.7E-10 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS25605 efb5494690d147b4906736489e08c9d3 883 SMART SM00240 232 283 2.8E-14 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS25605 efb5494690d147b4906736489e08c9d3 883 Pfam PF01061 ABC-2 type transporter 607 822 4.6E-20 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD11_RS25605 efb5494690d147b4906736489e08c9d3 883 Gene3D G3DSA:2.60.200.20 225 304 1.9E-21 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS25605 efb5494690d147b4906736489e08c9d3 883 Pfam PF00005 ABC transporter 335 482 1.9E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS25605 efb5494690d147b4906736489e08c9d3 883 SUPERFAMILY SSF49879 176 325 3.44E-24 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 SMD11_RS25605 efb5494690d147b4906736489e08c9d3 883 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS20145 60e6a2800062171faa28802067f11740 230 ProSitePatterns PS01081 TetR-type HTH domain signature. 52 82 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD11_RS20145 60e6a2800062171faa28802067f11740 230 Gene3D G3DSA:1.10.357.10 23 215 7.4E-48 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS20145 60e6a2800062171faa28802067f11740 230 SUPERFAMILY SSF48498 107 217 1.93E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS20145 60e6a2800062171faa28802067f11740 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 40 84 5.8E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS20145 60e6a2800062171faa28802067f11740 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 61 84 2.2E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS20145 60e6a2800062171faa28802067f11740 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 53 2.2E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS20145 60e6a2800062171faa28802067f11740 230 SUPERFAMILY SSF46689 26 106 1.45E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS17860 c1704916909ac7584322f0c7c503e93a 457 SMART SM00387 347 457 5.2E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS17860 c1704916909ac7584322f0c7c503e93a 457 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 306 3.0E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS17860 c1704916909ac7584322f0c7c503e93a 457 Pfam PF00672 HAMP domain 162 235 3.6E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS17860 c1704916909ac7584322f0c7c503e93a 457 SMART SM00304 181 239 5.9E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS17860 c1704916909ac7584322f0c7c503e93a 457 SMART SM00388 240 307 3.4E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS17860 c1704916909ac7584322f0c7c503e93a 457 Gene3D G3DSA:1.10.287.130 230 294 4.5E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS17860 c1704916909ac7584322f0c7c503e93a 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 435 1.3E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS17860 c1704916909ac7584322f0c7c503e93a 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 454 1.3E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS17860 c1704916909ac7584322f0c7c503e93a 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 398 1.3E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS17860 c1704916909ac7584322f0c7c503e93a 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 412 1.3E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS17860 c1704916909ac7584322f0c7c503e93a 457 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 456 3.6E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS17860 c1704916909ac7584322f0c7c503e93a 457 Gene3D G3DSA:3.30.565.10 295 454 5.4E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS17860 c1704916909ac7584322f0c7c503e93a 457 SUPERFAMILY SSF158472 182 237 7.72E-6 T 06-07-2017 SMD11_RS17860 c1704916909ac7584322f0c7c503e93a 457 SUPERFAMILY SSF55874 296 454 3.8E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS17860 c1704916909ac7584322f0c7c503e93a 457 SUPERFAMILY SSF47384 223 306 1.1E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SMD11_RS06390 735c74862754ec95b3e9fce0e9653601 454 Gene3D G3DSA:3.40.630.10 23 221 5.5E-57 T 06-07-2017 SMD11_RS06390 735c74862754ec95b3e9fce0e9653601 454 Gene3D G3DSA:3.40.630.10 388 452 5.5E-57 T 06-07-2017 SMD11_RS06390 735c74862754ec95b3e9fce0e9653601 454 Pfam PF07687 Peptidase dimerisation domain 210 336 6.8E-12 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS06390 735c74862754ec95b3e9fce0e9653601 454 Pfam PF01546 Peptidase family M20/M25/M40 92 451 1.8E-36 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD11_RS06390 735c74862754ec95b3e9fce0e9653601 454 Gene3D G3DSA:3.30.70.360 303 347 2.3E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS06390 735c74862754ec95b3e9fce0e9653601 454 Gene3D G3DSA:3.30.70.360 222 261 2.3E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS06390 735c74862754ec95b3e9fce0e9653601 454 SUPERFAMILY SSF53187 22 212 4.0E-54 T 06-07-2017 SMD11_RS06390 735c74862754ec95b3e9fce0e9653601 454 SUPERFAMILY SSF53187 363 452 4.0E-54 T 06-07-2017 SMD11_RS06390 735c74862754ec95b3e9fce0e9653601 454 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 91 100 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SMD11_RS06390 735c74862754ec95b3e9fce0e9653601 454 SUPERFAMILY SSF55031 302 338 1.44E-9 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS06390 735c74862754ec95b3e9fce0e9653601 454 SUPERFAMILY SSF55031 212 254 1.44E-9 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS33230 4b64eac7d249021742eba3b7a3f7eae1 396 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 17 390 1.0E-49 T 06-07-2017 SMD11_RS33230 4b64eac7d249021742eba3b7a3f7eae1 396 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 8 369 9.0E-91 T 06-07-2017 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 SMD11_RS22955 980bfb50c68222ba4f2734625baeab0a 311 Gene3D G3DSA:1.10.3720.10 70 304 7.9E-49 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS22955 980bfb50c68222ba4f2734625baeab0a 311 SUPERFAMILY SSF161098 64 298 9.16E-44 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS22955 980bfb50c68222ba4f2734625baeab0a 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 299 3.7E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS30085 398587d4a94263abd33545ae7e92e815 332 Gene3D G3DSA:2.80.10.50 264 320 3.2E-6 T 06-07-2017 SMD11_RS30085 398587d4a94263abd33545ae7e92e815 332 Gene3D G3DSA:2.80.10.50 159 263 6.3E-23 T 06-07-2017 SMD11_RS30085 398587d4a94263abd33545ae7e92e815 332 SUPERFAMILY SSF50370 187 322 1.98E-36 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS30085 398587d4a94263abd33545ae7e92e815 332 Gene3D G3DSA:2.80.10.50 46 158 5.5E-18 T 06-07-2017 SMD11_RS30085 398587d4a94263abd33545ae7e92e815 332 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 221 308 1.7E-18 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS30085 398587d4a94263abd33545ae7e92e815 332 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 44 117 1.3E-14 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS30085 398587d4a94263abd33545ae7e92e815 332 SMART SM00458 185 321 1.9E-4 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS30085 398587d4a94263abd33545ae7e92e815 332 SMART SM00458 41 179 1.4 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS30085 398587d4a94263abd33545ae7e92e815 332 SUPERFAMILY SSF50370 44 168 2.23E-23 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS11595 2c8e972d0acc57722d484a3ad1cc82d0 466 Pfam PF01546 Peptidase family M20/M25/M40 88 456 2.3E-35 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD11_RS11595 2c8e972d0acc57722d484a3ad1cc82d0 466 Gene3D G3DSA:3.30.70.360 204 367 9.7E-55 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS11595 2c8e972d0acc57722d484a3ad1cc82d0 466 SUPERFAMILY SSF53187 375 460 4.1E-62 T 06-07-2017 SMD11_RS11595 2c8e972d0acc57722d484a3ad1cc82d0 466 SUPERFAMILY SSF53187 9 204 4.1E-62 T 06-07-2017 SMD11_RS11595 2c8e972d0acc57722d484a3ad1cc82d0 466 Pfam PF07687 Peptidase dimerisation domain 201 360 1.7E-23 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS11595 2c8e972d0acc57722d484a3ad1cc82d0 466 Gene3D G3DSA:3.40.630.10 374 461 1.6E-63 T 06-07-2017 SMD11_RS11595 2c8e972d0acc57722d484a3ad1cc82d0 466 Gene3D G3DSA:3.40.630.10 9 198 1.6E-63 T 06-07-2017 SMD11_RS04210 7e6a9f811fa4d03ffda1e96cbc134f8c 304 Gene3D G3DSA:1.20.120.520 145 294 5.7E-31 T 06-07-2017 SMD11_RS04210 7e6a9f811fa4d03ffda1e96cbc134f8c 304 Gene3D G3DSA:2.30.110.10 26 119 3.5E-6 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS04210 7e6a9f811fa4d03ffda1e96cbc134f8c 304 Pfam PF01814 Hemerythrin HHE cation binding domain 150 291 9.6E-15 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 SMD11_RS04210 7e6a9f811fa4d03ffda1e96cbc134f8c 304 SUPERFAMILY SSF50475 28 151 1.88E-6 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS04210 7e6a9f811fa4d03ffda1e96cbc134f8c 304 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 22 132 8.9E-32 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD11_RS04210 7e6a9f811fa4d03ffda1e96cbc134f8c 304 Pfam PF04075 Domain of unknown function (DUF385) 11 133 4.2E-42 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD11_RS08915 2e99efaa04299284d74a86d09d68be8e 306 Gene3D G3DSA:3.40.190.10 254 287 2.4E-28 T 06-07-2017 SMD11_RS08915 2e99efaa04299284d74a86d09d68be8e 306 Gene3D G3DSA:3.40.190.10 67 150 2.4E-28 T 06-07-2017 SMD11_RS08915 2e99efaa04299284d74a86d09d68be8e 306 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 70 287 5.0E-50 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD11_RS08915 2e99efaa04299284d74a86d09d68be8e 306 SMART SM00062 69 293 7.3E-66 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD11_RS08915 2e99efaa04299284d74a86d09d68be8e 306 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 93 106 - T 06-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 SMD11_RS08915 2e99efaa04299284d74a86d09d68be8e 306 Gene3D G3DSA:3.40.190.10 151 253 1.5E-25 T 06-07-2017 SMD11_RS08915 2e99efaa04299284d74a86d09d68be8e 306 SUPERFAMILY SSF53850 59 287 7.75E-55 T 06-07-2017 SMD11_RS08915 2e99efaa04299284d74a86d09d68be8e 306 SUPERFAMILY SSF53850 5 22 7.75E-55 T 06-07-2017 SMD11_RS11385 6a425fb345d40959834510444e2d7303 448 SMART SM00471 236 371 1.3E-12 T 06-07-2017 IPR003607 HD/PDEase domain SMD11_RS11385 6a425fb345d40959834510444e2d7303 448 Pfam PF13487 HD domain 291 352 1.4E-21 T 06-07-2017 SMD11_RS11385 6a425fb345d40959834510444e2d7303 448 Gene3D G3DSA:1.10.3210.10 237 400 7.0E-23 T 06-07-2017 IPR006674 HD domain SMD11_RS11385 6a425fb345d40959834510444e2d7303 448 SUPERFAMILY SSF109604 225 401 1.17E-38 T 06-07-2017 SMD11_RS11385 6a425fb345d40959834510444e2d7303 448 TIGRFAM TIGR00277 HDIG: HDIG domain 241 330 1.1E-7 T 06-07-2017 IPR006675 HDIG domain SMD11_RS30825 ae17442f57db9ea70b8df156ec9a20e2 155 Gene3D G3DSA:2.30.110.10 4 133 2.4E-30 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS30825 ae17442f57db9ea70b8df156ec9a20e2 155 SUPERFAMILY SSF50475 4 133 3.6E-30 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS30825 ae17442f57db9ea70b8df156ec9a20e2 155 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 16 129 8.2E-29 T 06-07-2017 IPR019920 F420-binding domain, putative SMD11_RS30825 ae17442f57db9ea70b8df156ec9a20e2 155 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 4 86 1.5E-16 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD11_RS01060 437f1ded2c8f4fcba4cf219d60ae18c9 103 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 39 53 4.7E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS01060 437f1ded2c8f4fcba4cf219d60ae18c9 103 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 53 69 4.7E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS01060 437f1ded2c8f4fcba4cf219d60ae18c9 103 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 69 81 4.7E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS01060 437f1ded2c8f4fcba4cf219d60ae18c9 103 SUPERFAMILY SSF46894 29 99 1.73E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS01060 437f1ded2c8f4fcba4cf219d60ae18c9 103 Gene3D G3DSA:1.10.10.10 27 98 7.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01060 437f1ded2c8f4fcba4cf219d60ae18c9 103 SMART SM00421 36 93 4.3E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS01060 437f1ded2c8f4fcba4cf219d60ae18c9 103 Pfam PF00196 Bacterial regulatory proteins, luxR family 38 93 2.1E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS02170 7c1b21736a6a0bd2c6404a6bfd6493d3 139 Pfam PF04965 Gene 25-like lysozyme 40 125 1.2E-16 T 06-07-2017 IPR007048 GpW/Gp25/anti-adapter protein IraD SMD11_RS02170 7c1b21736a6a0bd2c6404a6bfd6493d3 139 Gene3D G3DSA:3.10.450.40 20 129 1.4E-28 T 06-07-2017 SMD11_RS02170 7c1b21736a6a0bd2c6404a6bfd6493d3 139 SUPERFAMILY SSF160719 38 130 1.2E-20 T 06-07-2017 SMD11_RS22490 4a973fcf76580afd249322e5d7d8df95 369 Gene3D G3DSA:3.30.2010.10 80 166 3.0E-21 T 06-07-2017 SMD11_RS22490 4a973fcf76580afd249322e5d7d8df95 369 Pfam PF01435 Peptidase family M48 86 280 1.5E-24 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMD11_RS17885 4971ce61ba4a1dadfdaacebb93685b39 332 SMART SM00382 37 215 9.8E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS17885 4971ce61ba4a1dadfdaacebb93685b39 332 Gene3D G3DSA:3.40.50.300 5 227 5.2E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17885 4971ce61ba4a1dadfdaacebb93685b39 332 SUPERFAMILY SSF52540 4 229 1.88E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17885 4971ce61ba4a1dadfdaacebb93685b39 332 Pfam PF00005 ABC transporter 29 166 1.1E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS17885 4971ce61ba4a1dadfdaacebb93685b39 332 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS10035 2e08ce19482c7b1a55eea03fb6b4b895 336 SUPERFAMILY SSF46689 111 172 7.48E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS10035 2e08ce19482c7b1a55eea03fb6b4b895 336 SUPERFAMILY SSF48498 182 329 1.45E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS10035 2e08ce19482c7b1a55eea03fb6b4b895 336 SMART SM00345 21 80 2.9E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS10035 2e08ce19482c7b1a55eea03fb6b4b895 336 Gene3D G3DSA:1.10.357.10 107 329 3.5E-51 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS10035 2e08ce19482c7b1a55eea03fb6b4b895 336 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 80 3.2E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS10035 2e08ce19482c7b1a55eea03fb6b4b895 336 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 179 324 9.6E-17 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD11_RS10035 2e08ce19482c7b1a55eea03fb6b4b895 336 Pfam PF00440 Bacterial regulatory proteins, tetR family 121 162 2.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS10035 2e08ce19482c7b1a55eea03fb6b4b895 336 Gene3D G3DSA:1.10.10.10 18 83 5.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS10035 2e08ce19482c7b1a55eea03fb6b4b895 336 SUPERFAMILY SSF46785 16 84 4.79E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16810 f4a5b2f8bbec276495ef493baafcfb97 360 Gene3D G3DSA:3.30.360.10 190 300 4.5E-48 T 06-07-2017 SMD11_RS16810 f4a5b2f8bbec276495ef493baafcfb97 360 SUPERFAMILY SSF51735 3 185 4.14E-92 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS16810 f4a5b2f8bbec276495ef493baafcfb97 360 SUPERFAMILY SSF51735 297 356 4.14E-92 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS16810 f4a5b2f8bbec276495ef493baafcfb97 360 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 4 354 4.9E-220 T 06-07-2017 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria SMD11_RS16810 f4a5b2f8bbec276495ef493baafcfb97 360 Pfam PF01658 Myo-inositol-1-phosphate synthase 191 300 1.8E-32 T 06-07-2017 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 SMD11_RS16810 f4a5b2f8bbec276495ef493baafcfb97 360 SUPERFAMILY SSF55347 190 299 7.98E-35 T 06-07-2017 SMD11_RS16810 f4a5b2f8bbec276495ef493baafcfb97 360 Gene3D G3DSA:3.40.50.720 301 355 2.9E-115 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS16810 f4a5b2f8bbec276495ef493baafcfb97 360 Gene3D G3DSA:3.40.50.720 1 189 2.9E-115 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS16810 f4a5b2f8bbec276495ef493baafcfb97 360 PIRSF PIRSF015578 1 360 8.0E-94 T 06-07-2017 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 SMD11_RS11150 e6e355c4d9d3891c6a1ca582cdebfcb4 221 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 113 217 6.0E-20 T 06-07-2017 IPR005519 Acid phosphatase, class B-like SMD11_RS11150 e6e355c4d9d3891c6a1ca582cdebfcb4 221 Gene3D G3DSA:3.40.50.1000 92 130 3.5E-4 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS11150 e6e355c4d9d3891c6a1ca582cdebfcb4 221 Gene3D G3DSA:3.40.50.1000 131 205 3.0E-5 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS11150 e6e355c4d9d3891c6a1ca582cdebfcb4 221 SUPERFAMILY SSF56784 88 206 6.37E-10 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS32935 36252563f3345597b26801d6b877a7e4 294 Pfam PF00668 Condensation domain 51 270 4.3E-52 T 06-07-2017 IPR001242 Condensation domain SMD11_RS32935 36252563f3345597b26801d6b877a7e4 294 SUPERFAMILY SSF52777 49 220 1.48E-53 T 06-07-2017 SMD11_RS00775 5fb3a207a567bb2caabc13ada8c06bd4 347 SUPERFAMILY SSF51735 149 314 1.25E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00775 5fb3a207a567bb2caabc13ada8c06bd4 347 SUPERFAMILY SSF50129 1 169 5.63E-48 T 06-07-2017 IPR011032 GroES-like SMD11_RS00775 5fb3a207a567bb2caabc13ada8c06bd4 347 Pfam PF00107 Zinc-binding dehydrogenase 180 309 1.2E-23 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS00775 5fb3a207a567bb2caabc13ada8c06bd4 347 Gene3D G3DSA:3.40.50.720 174 292 2.5E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00775 5fb3a207a567bb2caabc13ada8c06bd4 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 128 2.9E-24 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS00775 5fb3a207a567bb2caabc13ada8c06bd4 347 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 3.1E-6 T 06-07-2017 IPR027399 Alcohol dehydrogenase GroES-associated SMD11_RS00775 5fb3a207a567bb2caabc13ada8c06bd4 347 Gene3D G3DSA:3.90.180.10 1 173 4.5E-39 T 06-07-2017 IPR011032 GroES-like SMD11_RS09745 4ec3ded3c96671d4c40ca5a7c3e3ced1 277 Pfam PF08543 Phosphomethylpyrimidine kinase 23 270 1.6E-90 T 06-07-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 SMD11_RS09745 4ec3ded3c96671d4c40ca5a7c3e3ced1 277 SUPERFAMILY SSF53613 13 275 1.34E-77 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS09745 4ec3ded3c96671d4c40ca5a7c3e3ced1 277 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 16 271 1.4E-92 T 06-07-2017 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SMD11_RS09745 4ec3ded3c96671d4c40ca5a7c3e3ced1 277 Gene3D G3DSA:3.40.1190.20 14 271 7.6E-100 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS13805 1b98d0e577b785d03c39c0160b6e183d 261 Pfam PF01048 Phosphorylase superfamily 60 231 5.3E-8 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD11_RS13805 1b98d0e577b785d03c39c0160b6e183d 261 SUPERFAMILY SSF53167 58 229 4.73E-23 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD11_RS13805 1b98d0e577b785d03c39c0160b6e183d 261 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 3 244 6.6E-59 T 06-07-2017 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 SMD11_RS13805 1b98d0e577b785d03c39c0160b6e183d 261 Gene3D G3DSA:3.40.50.1580 1 250 6.0E-44 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SMD11_RS13805 1b98d0e577b785d03c39c0160b6e183d 261 Hamap MF_00991 Futalosine hydrolase [mqnB]. 42 247 25.313 T 06-07-2017 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 SMD11_RS30790 b0ceb0e810282194a953c33a127c52e4 387 PIRSF PIRSF029347 1 387 6.4E-134 T 06-07-2017 IPR014555 RecF-like SMD11_RS30790 b0ceb0e810282194a953c33a127c52e4 387 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 246 341 2.4E-17 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS30790 b0ceb0e810282194a953c33a127c52e4 387 SUPERFAMILY SSF52540 252 344 9.34E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30790 b0ceb0e810282194a953c33a127c52e4 387 SUPERFAMILY SSF52540 1 204 9.34E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30790 b0ceb0e810282194a953c33a127c52e4 387 Pfam PF13175 AAA ATPase domain 1 48 2.8E-9 T 06-07-2017 SMD11_RS30790 b0ceb0e810282194a953c33a127c52e4 387 Gene3D G3DSA:3.40.50.300 260 344 5.4E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30790 b0ceb0e810282194a953c33a127c52e4 387 Gene3D G3DSA:3.40.50.300 1 60 1.1E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25815 130adaf21de3b27f9a0be702c1c898c7 381 Gene3D G3DSA:3.40.50.300 127 378 1.1E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25815 130adaf21de3b27f9a0be702c1c898c7 381 SUPERFAMILY SSF52540 126 378 8.99E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25815 130adaf21de3b27f9a0be702c1c898c7 381 Pfam PF13614 AAA domain 127 302 1.1E-61 T 06-07-2017 IPR025669 AAA domain SMD11_RS24780 b7635d0c3dc4adc233c66cb583c7e089 243 Pfam PF01988 VIT family 28 235 1.8E-61 T 06-07-2017 IPR008217 Ccc1 family SMD11_RS02680 0640535345fdcdd451e088131382626c 381 Pfam PF01266 FAD dependent oxidoreductase 7 358 1.3E-62 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD11_RS02680 0640535345fdcdd451e088131382626c 381 SUPERFAMILY SSF54373 218 320 5.1E-11 T 06-07-2017 SMD11_RS02680 0640535345fdcdd451e088131382626c 381 SUPERFAMILY SSF51905 6 218 6.34E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02680 0640535345fdcdd451e088131382626c 381 SUPERFAMILY SSF51905 320 379 6.34E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02680 0640535345fdcdd451e088131382626c 381 Gene3D G3DSA:3.30.9.10 88 140 9.2E-16 T 06-07-2017 SMD11_RS02680 0640535345fdcdd451e088131382626c 381 Gene3D G3DSA:3.30.9.10 218 318 9.2E-16 T 06-07-2017 SMD11_RS02680 0640535345fdcdd451e088131382626c 381 Gene3D G3DSA:3.50.50.60 141 217 1.8E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02680 0640535345fdcdd451e088131382626c 381 Gene3D G3DSA:3.50.50.60 320 379 1.8E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02680 0640535345fdcdd451e088131382626c 381 Gene3D G3DSA:3.50.50.60 3 83 1.8E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02795 bf33d56a5ceff7baf72fce8bf2a2500b 240 Pfam PF13936 Helix-turn-helix domain 5 45 2.6E-13 T 06-07-2017 IPR025246 Transposase IS30-like HTH domain SMD11_RS02795 bf33d56a5ceff7baf72fce8bf2a2500b 240 Gene3D G3DSA:1.10.10.10 87 167 3.8E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02795 bf33d56a5ceff7baf72fce8bf2a2500b 240 Pfam PF12802 MarR family 104 163 1.7E-10 T 06-07-2017 SMD11_RS02795 bf33d56a5ceff7baf72fce8bf2a2500b 240 SUPERFAMILY SSF46785 87 187 1.03E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16705 0d6269b5a1ddd60528954ab160921418 144 SMART SM00422 1 69 4.0E-24 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS16705 0d6269b5a1ddd60528954ab160921418 144 Gene3D G3DSA:1.10.1660.10 55 116 3.5E-10 T 06-07-2017 SMD11_RS16705 0d6269b5a1ddd60528954ab160921418 144 SUPERFAMILY SSF46955 1 112 1.5E-27 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS16705 0d6269b5a1ddd60528954ab160921418 144 Gene3D G3DSA:1.10.1660.10 1 54 3.5E-24 T 06-07-2017 SMD11_RS16705 0d6269b5a1ddd60528954ab160921418 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.2E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS16705 0d6269b5a1ddd60528954ab160921418 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.2E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS16705 0d6269b5a1ddd60528954ab160921418 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.2E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS16705 0d6269b5a1ddd60528954ab160921418 144 Pfam PF13411 MerR HTH family regulatory protein 1 61 4.8E-18 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS00785 c762e631c9ab4a9b9d8ae6573f3f29b5 406 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 193 206 6.6E-12 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS00785 c762e631c9ab4a9b9d8ae6573f3f29b5 406 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 62 80 6.6E-12 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS00785 c762e631c9ab4a9b9d8ae6573f3f29b5 406 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 276 295 6.6E-12 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS00785 c762e631c9ab4a9b9d8ae6573f3f29b5 406 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 82 94 6.6E-12 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SMD11_RS00785 c762e631c9ab4a9b9d8ae6573f3f29b5 406 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 293 402 5.5E-6 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SMD11_RS00785 c762e631c9ab4a9b9d8ae6573f3f29b5 406 SUPERFAMILY SSF51419 39 289 3.63E-61 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS00785 c762e631c9ab4a9b9d8ae6573f3f29b5 406 SUPERFAMILY SSF50621 271 403 4.6E-28 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS00785 c762e631c9ab4a9b9d8ae6573f3f29b5 406 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 46 286 9.9E-35 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SMD11_RS00785 c762e631c9ab4a9b9d8ae6573f3f29b5 406 Gene3D G3DSA:2.40.37.10 273 402 6.9E-25 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SMD11_RS00785 c762e631c9ab4a9b9d8ae6573f3f29b5 406 PRINTS PR01182 Ornithine decarboxylase signature 103 127 6.6E-6 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 SMD11_RS00785 c762e631c9ab4a9b9d8ae6573f3f29b5 406 PRINTS PR01182 Ornithine decarboxylase signature 60 87 6.6E-6 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 SMD11_RS00785 c762e631c9ab4a9b9d8ae6573f3f29b5 406 PRINTS PR01182 Ornithine decarboxylase signature 371 384 6.6E-6 T 06-07-2017 IPR002433 Ornithine decarboxylase GO:0006596 SMD11_RS00785 c762e631c9ab4a9b9d8ae6573f3f29b5 406 Gene3D G3DSA:3.20.20.10 42 272 3.1E-70 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS11705 0542a20edd8eb2a3862834c77f6b1904 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 2.6E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS11705 0542a20edd8eb2a3862834c77f6b1904 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 2.6E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS11705 0542a20edd8eb2a3862834c77f6b1904 212 SUPERFAMILY SSF46689 11 92 1.75E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS11705 0542a20edd8eb2a3862834c77f6b1904 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 5.5E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS11705 0542a20edd8eb2a3862834c77f6b1904 212 Gene3D G3DSA:1.10.357.10 10 209 1.5E-41 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS11705 0542a20edd8eb2a3862834c77f6b1904 212 SUPERFAMILY SSF48498 92 203 6.35E-27 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS18965 72e21002b298d2fe580cc5f8462dfe4a 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 4.2E-74 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMD11_RS18965 72e21002b298d2fe580cc5f8462dfe4a 179 Gene3D G3DSA:3.90.930.12 2 83 7.1E-30 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18965 72e21002b298d2fe580cc5f8462dfe4a 179 Pfam PF00347 Ribosomal protein L6 92 165 2.1E-20 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18965 72e21002b298d2fe580cc5f8462dfe4a 179 Pfam PF00347 Ribosomal protein L6 11 83 2.1E-18 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18965 72e21002b298d2fe580cc5f8462dfe4a 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 5.6E-32 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMD11_RS18965 72e21002b298d2fe580cc5f8462dfe4a 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 5.6E-32 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMD11_RS18965 72e21002b298d2fe580cc5f8462dfe4a 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 5.6E-32 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMD11_RS18965 72e21002b298d2fe580cc5f8462dfe4a 179 Gene3D G3DSA:3.90.930.12 84 178 1.6E-38 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18965 72e21002b298d2fe580cc5f8462dfe4a 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.504 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SMD11_RS18965 72e21002b298d2fe580cc5f8462dfe4a 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 06-07-2017 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18965 72e21002b298d2fe580cc5f8462dfe4a 179 SUPERFAMILY SSF56053 1 83 1.1E-25 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18965 72e21002b298d2fe580cc5f8462dfe4a 179 SUPERFAMILY SSF56053 84 177 1.57E-35 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18965 72e21002b298d2fe580cc5f8462dfe4a 179 PIRSF PIRSF002162 1 178 2.6E-48 T 06-07-2017 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18825 5297ddcd5a356c14bbba0819d501e1b3 238 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 1 228 42.563 T 06-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 SMD11_RS18825 5297ddcd5a356c14bbba0819d501e1b3 238 PIRSF PIRSF002155 1 226 2.0E-73 T 06-07-2017 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18825 5297ddcd5a356c14bbba0819d501e1b3 238 Gene3D G3DSA:3.40.50.790 69 158 5.6E-41 T 06-07-2017 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich SMD11_RS18825 5297ddcd5a356c14bbba0819d501e1b3 238 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 2 226 1.6E-101 T 06-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 SMD11_RS18825 5297ddcd5a356c14bbba0819d501e1b3 238 Gene3D G3DSA:3.30.190.20 159 227 6.0E-45 T 06-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 SMD11_RS18825 5297ddcd5a356c14bbba0819d501e1b3 238 Gene3D G3DSA:3.30.190.20 19 68 6.0E-45 T 06-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 SMD11_RS18825 5297ddcd5a356c14bbba0819d501e1b3 238 ProSitePatterns PS01199 Ribosomal protein L1 signature. 120 138 - T 06-07-2017 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS18825 5297ddcd5a356c14bbba0819d501e1b3 238 SUPERFAMILY SSF56808 6 225 3.66E-81 T 06-07-2017 IPR023674 Ribosomal protein L1-like SMD11_RS18825 5297ddcd5a356c14bbba0819d501e1b3 238 Pfam PF00687 Ribosomal protein L1p/L10e family 30 219 3.4E-53 T 06-07-2017 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein SMD11_RS29535 879f9f49ff1c956cc4c823d480bad032 262 SUPERFAMILY SSF52540 56 192 6.92E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29535 879f9f49ff1c956cc4c823d480bad032 262 Gene3D G3DSA:3.40.50.300 48 73 2.5E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29535 879f9f49ff1c956cc4c823d480bad032 262 Pfam PF13671 AAA domain 65 197 2.9E-8 T 06-07-2017 SMD11_RS29535 879f9f49ff1c956cc4c823d480bad032 262 Gene3D G3DSA:3.40.50.300 74 190 4.7E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13115 e2fb19c7e8dc719c2de11242c57430d2 400 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 7 399 5.6E-144 T 06-07-2017 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SMD11_RS13115 e2fb19c7e8dc719c2de11242c57430d2 400 SUPERFAMILY SSF53383 7 399 3.2E-117 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS13115 e2fb19c7e8dc719c2de11242c57430d2 400 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS13115 e2fb19c7e8dc719c2de11242c57430d2 400 Gene3D G3DSA:3.40.640.10 60 304 5.9E-84 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS13115 e2fb19c7e8dc719c2de11242c57430d2 400 Pfam PF00202 Aminotransferase class-III 16 399 5.3E-113 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS13115 e2fb19c7e8dc719c2de11242c57430d2 400 Gene3D G3DSA:3.90.1150.10 308 399 1.5E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS13115 e2fb19c7e8dc719c2de11242c57430d2 400 Gene3D G3DSA:3.90.1150.10 8 58 1.5E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS20575 bdb19bdca469b6a013b2aed6c4e2ae6e 168 Pfam PF04138 GtrA-like protein 20 141 3.6E-24 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 SMD11_RS00540 02ef88b07b4aa7789e8e2b6af7c26f5e 194 SUPERFAMILY SSF52980 26 156 4.45E-18 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD11_RS00540 02ef88b07b4aa7789e8e2b6af7c26f5e 194 Gene3D G3DSA:3.90.1570.10 29 152 6.0E-18 T 06-07-2017 IPR012296 Nuclease, putative, TT1808 SMD11_RS00540 02ef88b07b4aa7789e8e2b6af7c26f5e 194 Pfam PF05685 Putative restriction endonuclease 27 150 2.0E-17 T 06-07-2017 IPR008538 Domain of unknown function DUF820 SMD11_RS28535 19f596faaf4c6de58a5738fc0ca70b17 309 Pfam PF13649 Methyltransferase domain 71 167 1.3E-14 T 06-07-2017 SMD11_RS28535 19f596faaf4c6de58a5738fc0ca70b17 309 Gene3D G3DSA:3.40.50.150 212 236 7.8E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS28535 19f596faaf4c6de58a5738fc0ca70b17 309 Gene3D G3DSA:3.40.50.150 64 173 7.8E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS28535 19f596faaf4c6de58a5738fc0ca70b17 309 SUPERFAMILY SSF53335 44 292 7.52E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS30725 2597d8f8352089f717950ebaf4c05b5b 307 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 156 1.7E-13 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS30725 2597d8f8352089f717950ebaf4c05b5b 307 SUPERFAMILY SSF54427 167 283 5.71E-14 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS30725 2597d8f8352089f717950ebaf4c05b5b 307 Gene3D G3DSA:3.10.450.50 167 283 1.2E-14 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS30725 2597d8f8352089f717950ebaf4c05b5b 307 Pfam PF08281 Sigma-70, region 4 105 156 1.6E-11 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS30725 2597d8f8352089f717950ebaf4c05b5b 307 Gene3D G3DSA:1.10.10.10 109 157 5.0E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30725 2597d8f8352089f717950ebaf4c05b5b 307 Gene3D G3DSA:1.10.1740.10 6 71 1.3E-9 T 06-07-2017 SMD11_RS30725 2597d8f8352089f717950ebaf4c05b5b 307 SUPERFAMILY SSF88659 102 157 2.24E-10 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS30725 2597d8f8352089f717950ebaf4c05b5b 307 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 5 286 5.3E-113 T 06-07-2017 IPR014303 RNA polymerase sigma-70, ECF type SMD11_RS30725 2597d8f8352089f717950ebaf4c05b5b 307 Pfam PF04542 Sigma-70 region 2 7 69 6.2E-10 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS30725 2597d8f8352089f717950ebaf4c05b5b 307 SUPERFAMILY SSF88946 7 83 3.65E-11 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS03955 9052f51d6104439d9447082654daffcd 161 Gene3D G3DSA:3.40.50.620 24 161 1.8E-24 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS03955 9052f51d6104439d9447082654daffcd 161 Pfam PF00582 Universal stress protein family 25 161 3.9E-23 T 06-07-2017 IPR006016 UspA GO:0006950 SMD11_RS03955 9052f51d6104439d9447082654daffcd 161 PRINTS PR01438 Universal stress protein signature 24 42 3.0E-6 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS03955 9052f51d6104439d9447082654daffcd 161 PRINTS PR01438 Universal stress protein signature 139 161 3.0E-6 T 06-07-2017 IPR006015 Universal stress protein A SMD11_RS03955 9052f51d6104439d9447082654daffcd 161 SUPERFAMILY SSF52402 25 161 6.7E-24 T 06-07-2017 SMD11_RS25760 a627308672c64f7c0aa1a11ac1bcce27 271 SUPERFAMILY SSF53335 59 251 5.9E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS25760 a627308672c64f7c0aa1a11ac1bcce27 271 SUPERFAMILY SSF55174 7 59 3.53E-11 T 06-07-2017 SMD11_RS25760 a627308672c64f7c0aa1a11ac1bcce27 271 Pfam PF01728 FtsJ-like methyltransferase 65 250 2.1E-18 T 06-07-2017 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 SMD11_RS25760 a627308672c64f7c0aa1a11ac1bcce27 271 Pfam PF01479 S4 domain 8 50 3.7E-10 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 SMD11_RS25760 a627308672c64f7c0aa1a11ac1bcce27 271 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 8 245 2.9E-59 T 06-07-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 SMD11_RS25760 a627308672c64f7c0aa1a11ac1bcce27 271 Gene3D G3DSA:3.10.290.10 7 98 9.5E-24 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 SMD11_RS25760 a627308672c64f7c0aa1a11ac1bcce27 271 Gene3D G3DSA:3.40.50.150 99 186 4.9E-7 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS25760 a627308672c64f7c0aa1a11ac1bcce27 271 SMART SM00363 7 74 8.1E-7 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 SMD11_RS25760 a627308672c64f7c0aa1a11ac1bcce27 271 PIRSF PIRSF005578 2 268 7.2E-94 T 06-07-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 SMD11_RS10360 e18283deb487c59c205bf5a2c0b8a5a6 637 Pfam PF00664 ABC transporter transmembrane region 74 340 2.3E-32 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS10360 e18283deb487c59c205bf5a2c0b8a5a6 637 ProSitePatterns PS00211 ABC transporters family signature. 534 548 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS10360 e18283deb487c59c205bf5a2c0b8a5a6 637 SMART SM00382 422 608 3.2E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS10360 e18283deb487c59c205bf5a2c0b8a5a6 637 Gene3D G3DSA:3.40.50.300 397 623 3.8E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10360 e18283deb487c59c205bf5a2c0b8a5a6 637 Pfam PF00005 ABC transporter 416 562 6.5E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS10360 e18283deb487c59c205bf5a2c0b8a5a6 637 SUPERFAMILY SSF52540 394 631 1.25E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10360 e18283deb487c59c205bf5a2c0b8a5a6 637 Gene3D G3DSA:1.20.1560.10 61 379 4.6E-78 T 06-07-2017 SMD11_RS10360 e18283deb487c59c205bf5a2c0b8a5a6 637 SUPERFAMILY SSF90123 61 382 2.75E-66 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS13490 920acf511e0e64747676a93c1d4d5062 150 Gene3D G3DSA:3.10.180.10 4 134 5.1E-15 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS13490 920acf511e0e64747676a93c1d4d5062 150 SUPERFAMILY SSF54593 3 130 1.37E-14 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS12395 2a935539986471472c073aab6f3cfc6f 537 SUPERFAMILY SSF51338 1 58 2.56E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS12395 2a935539986471472c073aab6f3cfc6f 537 SUPERFAMILY SSF51338 472 524 2.56E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS12395 2a935539986471472c073aab6f3cfc6f 537 Gene3D G3DSA:2.30.40.10 1 71 3.0E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS12395 2a935539986471472c073aab6f3cfc6f 537 Gene3D G3DSA:3.20.20.140 72 291 9.4E-115 T 06-07-2017 SMD11_RS12395 2a935539986471472c073aab6f3cfc6f 537 Gene3D G3DSA:3.20.20.140 396 456 9.4E-115 T 06-07-2017 SMD11_RS12395 2a935539986471472c073aab6f3cfc6f 537 SUPERFAMILY SSF51556 58 299 3.66E-74 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS12395 2a935539986471472c073aab6f3cfc6f 537 SUPERFAMILY SSF51556 342 472 3.66E-74 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS12395 2a935539986471472c073aab6f3cfc6f 537 Gene3D G3DSA:2.30.40.10 457 534 2.4E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS12395 2a935539986471472c073aab6f3cfc6f 537 Pfam PF07969 Amidohydrolase family 46 516 4.5E-62 T 06-07-2017 IPR013108 Amidohydrolase 3 SMD11_RS02995 21f1876d18c921d0639cf4951d497cbc 441 Pfam PF07690 Major Facilitator Superfamily 253 432 1.8E-18 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS02995 21f1876d18c921d0639cf4951d497cbc 441 SUPERFAMILY SSF103473 21 423 3.14E-49 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS02995 21f1876d18c921d0639cf4951d497cbc 441 Gene3D G3DSA:1.20.1250.20 22 210 2.3E-18 T 06-07-2017 SMD11_RS02995 21f1876d18c921d0639cf4951d497cbc 441 Gene3D G3DSA:1.20.1250.20 245 424 2.8E-22 T 06-07-2017 SMD11_RS02995 21f1876d18c921d0639cf4951d497cbc 441 Pfam PF00083 Sugar (and other) transporter 57 210 7.5E-9 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMD11_RS14935 66d04215628d21f48943276a733cbcbe 301 SUPERFAMILY SSF51717 19 283 1.83E-90 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS14935 66d04215628d21f48943276a733cbcbe 301 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 21 282 3.9E-87 T 06-07-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 SMD11_RS14935 66d04215628d21f48943276a733cbcbe 301 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 55 68 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS14935 66d04215628d21f48943276a733cbcbe 301 Pfam PF00809 Pterin binding enzyme 22 268 1.7E-82 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS14935 66d04215628d21f48943276a733cbcbe 301 Gene3D G3DSA:3.20.20.20 17 285 1.8E-102 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS14935 66d04215628d21f48943276a733cbcbe 301 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 21 36 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SMD11_RS28875 2b215c7b977d785bf80910894c238368 412 Pfam PF08245 Mur ligase middle domain 65 266 7.4E-12 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS28875 2b215c7b977d785bf80910894c238368 412 SUPERFAMILY SSF53623 47 281 6.87E-29 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS28875 2b215c7b977d785bf80910894c238368 412 Gene3D G3DSA:3.40.1190.10 47 284 8.6E-38 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SMD11_RS28875 2b215c7b977d785bf80910894c238368 412 Pfam PF08353 Domain of unknown function (DUF1727) 304 403 2.5E-21 T 06-07-2017 IPR013564 Domain of unknown function DUF1727 SMD11_RS21655 9fcf275ef16702bdfaef219cbc1083df 289 Gene3D G3DSA:3.40.50.150 30 277 1.2E-64 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS21655 9fcf275ef16702bdfaef219cbc1083df 289 Pfam PF01564 Spermine/spermidine synthase 60 186 9.3E-6 T 06-07-2017 SMD11_RS21655 9fcf275ef16702bdfaef219cbc1083df 289 SUPERFAMILY SSF53335 34 246 1.38E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS30995 60b1936b5146fba16110c9a916e89ebd 237 Pfam PF06912 Protein of unknown function (DUF1275) 30 223 1.3E-33 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 SMD11_RS04365 c0cbd2ec4065fdb9617930c72e9c5295 881 SUPERFAMILY SSF55186 561 719 5.1E-39 T 06-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 SMD11_RS04365 c0cbd2ec4065fdb9617930c72e9c5295 881 Pfam PF01411 tRNA synthetases class II (A) 5 564 2.1E-185 T 06-07-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 SMD11_RS04365 c0cbd2ec4065fdb9617930c72e9c5295 881 SUPERFAMILY SSF101353 249 443 9.68E-56 T 06-07-2017 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 SMD11_RS04365 c0cbd2ec4065fdb9617930c72e9c5295 881 Gene3D G3DSA:3.30.930.10 1 244 1.7E-93 T 06-07-2017 SMD11_RS04365 c0cbd2ec4065fdb9617930c72e9c5295 881 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 662 706 7.8E-15 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMD11_RS04365 c0cbd2ec4065fdb9617930c72e9c5295 881 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 861 4.1E-236 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD11_RS04365 c0cbd2ec4065fdb9617930c72e9c5295 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 1.2E-28 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD11_RS04365 c0cbd2ec4065fdb9617930c72e9c5295 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 1.2E-28 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD11_RS04365 c0cbd2ec4065fdb9617930c72e9c5295 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 1.2E-28 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD11_RS04365 c0cbd2ec4065fdb9617930c72e9c5295 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 1.2E-28 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD11_RS04365 c0cbd2ec4065fdb9617930c72e9c5295 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 1.2E-28 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD11_RS04365 c0cbd2ec4065fdb9617930c72e9c5295 881 SUPERFAMILY SSF50447 462 561 2.4E-16 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS04365 c0cbd2ec4065fdb9617930c72e9c5295 881 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 881 152.469 T 06-07-2017 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 SMD11_RS04365 c0cbd2ec4065fdb9617930c72e9c5295 881 SUPERFAMILY SSF55681 2 248 5.47E-88 T 06-07-2017 SMD11_RS04365 c0cbd2ec4065fdb9617930c72e9c5295 881 SMART SM00863 662 706 2.9E-17 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMD11_RS28075 5cd98a42f5cc740eacc86370c7c1354e 226 Gene3D G3DSA:3.40.50.300 44 216 1.6E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28075 5cd98a42f5cc740eacc86370c7c1354e 226 Pfam PF03029 Conserved hypothetical ATP binding protein 49 217 1.3E-26 T 06-07-2017 IPR004130 GPN-loop GTPase SMD11_RS28075 5cd98a42f5cc740eacc86370c7c1354e 226 SUPERFAMILY SSF52540 42 216 1.5E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27910 6e26f6ab7742b9ee2c7bfd84bb897745 196 Pfam PF13692 Glycosyl transferases group 1 40 160 5.1E-15 T 06-07-2017 SMD11_RS27910 6e26f6ab7742b9ee2c7bfd84bb897745 196 SUPERFAMILY SSF53756 42 189 8.9E-25 T 06-07-2017 SMD11_RS27910 6e26f6ab7742b9ee2c7bfd84bb897745 196 Gene3D G3DSA:3.40.50.2000 54 173 1.2E-5 T 06-07-2017 SMD11_RS32055 9cb1138e7896f2103e2536da43445fa7 91 Gene3D G3DSA:2.10.230.10 38 89 4.8E-4 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMD11_RS22365 4a29e75b5e45a1609aa1ef781019d6ea 373 Gene3D G3DSA:3.40.50.2000 200 361 1.4E-41 T 06-07-2017 SMD11_RS22365 4a29e75b5e45a1609aa1ef781019d6ea 373 Gene3D G3DSA:3.40.50.2000 4 199 3.4E-63 T 06-07-2017 SMD11_RS22365 4a29e75b5e45a1609aa1ef781019d6ea 373 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 360 1.8E-85 T 06-07-2017 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 SMD11_RS22365 4a29e75b5e45a1609aa1ef781019d6ea 373 SUPERFAMILY SSF53756 5 362 4.71E-93 T 06-07-2017 SMD11_RS22365 4a29e75b5e45a1609aa1ef781019d6ea 373 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 31 360 1.2E-92 T 06-07-2017 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS21305 2ef8702cf5e3afad8c60a8116c616740 106 Pfam PF12277 Protein of unknown function (DUF3618) 4 49 1.6E-16 T 06-07-2017 IPR022062 Protein of unknown function DUF3618 SMD11_RS06900 b83750269d95d28af5c20fbf26a3c9af 387 SUPERFAMILY SSF49785 223 368 1.62E-39 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS06900 b83750269d95d28af5c20fbf26a3c9af 387 PIRSF PIRSF016516 27 372 1.6E-93 T 06-07-2017 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 SMD11_RS06900 b83750269d95d28af5c20fbf26a3c9af 387 SUPERFAMILY SSF49785 35 213 3.53E-52 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS06900 b83750269d95d28af5c20fbf26a3c9af 387 Hamap MF_00813 Probable allantoicase [alc]. 30 371 48.711 T 06-07-2017 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 SMD11_RS06900 b83750269d95d28af5c20fbf26a3c9af 387 Gene3D G3DSA:2.60.120.260 221 370 8.5E-39 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS06900 b83750269d95d28af5c20fbf26a3c9af 387 Gene3D G3DSA:2.60.120.260 35 213 9.3E-54 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS06900 b83750269d95d28af5c20fbf26a3c9af 387 TIGRFAM TIGR02961 allantoicase: allantoicase 42 368 9.2E-120 T 06-07-2017 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 SMD11_RS06900 b83750269d95d28af5c20fbf26a3c9af 387 Pfam PF03561 Allantoicase repeat 232 368 4.2E-35 T 06-07-2017 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 SMD11_RS06900 b83750269d95d28af5c20fbf26a3c9af 387 Pfam PF03561 Allantoicase repeat 50 209 1.9E-44 T 06-07-2017 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 SMD11_RS03440 607bb5d99f76d3e75c75f4e48f62c76f 442 SUPERFAMILY SSF82171 55 427 6.28E-17 T 06-07-2017 SMD11_RS03440 607bb5d99f76d3e75c75f4e48f62c76f 442 Pfam PF07676 WD40-like Beta Propeller Repeat 163 191 1.0E-4 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS03440 607bb5d99f76d3e75c75f4e48f62c76f 442 Gene3D G3DSA:2.130.10.10 45 175 7.0E-12 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS03440 607bb5d99f76d3e75c75f4e48f62c76f 442 Gene3D G3DSA:2.120.10.60 176 402 3.5E-12 T 06-07-2017 SMD11_RS19655 2883af93e08320014a107fce86d795db 208 SUPERFAMILY SSF46689 8 80 1.99E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS19655 2883af93e08320014a107fce86d795db 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 62 3.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS19655 2883af93e08320014a107fce86d795db 208 Gene3D G3DSA:1.10.357.10 9 192 7.1E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS16425 e4fd84f9dfaac3bf9eb891633c87aa70 216 Pfam PF02630 SCO1/SenC 40 177 5.6E-24 T 06-07-2017 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS16425 e4fd84f9dfaac3bf9eb891633c87aa70 216 SUPERFAMILY SSF52833 49 212 1.97E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS16425 e4fd84f9dfaac3bf9eb891633c87aa70 216 Gene3D G3DSA:3.40.30.10 10 213 4.4E-42 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS08800 c65372531916e08a81034f8fa8abdeca 177 Gene3D G3DSA:2.60.60.30 6 168 6.2E-43 T 06-07-2017 SMD11_RS08800 c65372531916e08a81034f8fa8abdeca 177 Pfam PF02342 TerD domain 5 168 2.0E-22 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS25965 f2f29ef04436f6ab68c2e9e6594af278 145 Hamap MF_01197 Cell division protein SepF [sepF]. 1 137 19.246 T 06-07-2017 IPR023052 Cell division protein SepF GO:0090529 SMD11_RS25965 f2f29ef04436f6ab68c2e9e6594af278 145 Pfam PF04472 Protein of unknown function (DUF552) 57 128 4.9E-24 T 06-07-2017 IPR007561 Cell division protein SepF/SepF-related GO:0090529 SMD11_RS23495 4d3e8566f2a27ff2cebe30bcfbdecc8c 486 Pfam PF00171 Aldehyde dehydrogenase family 21 476 1.5E-151 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS23495 4d3e8566f2a27ff2cebe30bcfbdecc8c 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS23495 4d3e8566f2a27ff2cebe30bcfbdecc8c 486 Gene3D G3DSA:3.40.605.10 8 266 6.3E-83 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS23495 4d3e8566f2a27ff2cebe30bcfbdecc8c 486 Gene3D G3DSA:3.40.309.10 267 443 7.5E-65 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS23495 4d3e8566f2a27ff2cebe30bcfbdecc8c 486 SUPERFAMILY SSF53720 5 480 2.09E-153 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS26860 3ad9dfac8e6f744873e3e2735029dec4 489 Pfam PF00155 Aminotransferase class I and II 118 468 4.0E-31 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS26860 3ad9dfac8e6f744873e3e2735029dec4 489 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 93 1.8E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS26860 3ad9dfac8e6f744873e3e2735029dec4 489 Gene3D G3DSA:1.10.10.10 29 94 6.3E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26860 3ad9dfac8e6f744873e3e2735029dec4 489 Gene3D G3DSA:3.40.640.10 145 338 6.0E-45 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS26860 3ad9dfac8e6f744873e3e2735029dec4 489 SUPERFAMILY SSF46785 29 99 1.02E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26860 3ad9dfac8e6f744873e3e2735029dec4 489 Gene3D G3DSA:3.90.1150.10 339 472 2.3E-21 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS26860 3ad9dfac8e6f744873e3e2735029dec4 489 SMART SM00345 36 95 1.1E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS26860 3ad9dfac8e6f744873e3e2735029dec4 489 SUPERFAMILY SSF53383 113 473 1.12E-78 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS02275 6dc75b3e1098c6925496879487b6c199 444 SUPERFAMILY SSF52777 6 159 4.82E-15 T 06-07-2017 SMD11_RS02275 6dc75b3e1098c6925496879487b6c199 444 Pfam PF16911 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus 307 420 1.0E-15 T 06-07-2017 IPR031641 Phthiocerol/phthiodiolone dimycocerosyl transferase, C-terminal SMD11_RS02275 6dc75b3e1098c6925496879487b6c199 444 SUPERFAMILY SSF52777 212 428 8.15E-24 T 06-07-2017 SMD11_RS14885 fda08fc699e77b756aa950ea2a7d0702 398 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 324 398 1.3E-20 T 06-07-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS14885 fda08fc699e77b756aa950ea2a7d0702 398 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 149 320 2.8E-47 T 06-07-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS14885 fda08fc699e77b756aa950ea2a7d0702 398 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 71 82 - T 06-07-2017 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS14885 fda08fc699e77b756aa950ea2a7d0702 398 Gene3D G3DSA:1.10.645.10 31 386 2.4E-60 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS14885 fda08fc699e77b756aa950ea2a7d0702 398 SUPERFAMILY SSF56762 44 397 1.31E-101 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS14885 fda08fc699e77b756aa950ea2a7d0702 398 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 29 398 40.572 T 06-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS31835 70d1756de374fc79de1577ce7ecbc06f 359 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 15 206 2.3E-16 T 06-07-2017 IPR001099 Chalcone/stilbene synthase, N-terminal SMD11_RS31835 70d1756de374fc79de1577ce7ecbc06f 359 Gene3D G3DSA:3.40.47.10 219 359 1.8E-35 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS31835 70d1756de374fc79de1577ce7ecbc06f 359 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 222 357 2.9E-16 T 06-07-2017 IPR012328 Chalcone/stilbene synthase, C-terminal SMD11_RS31835 70d1756de374fc79de1577ce7ecbc06f 359 PIRSF PIRSF000451 1 359 1.3E-110 T 06-07-2017 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 SMD11_RS31835 70d1756de374fc79de1577ce7ecbc06f 359 Gene3D G3DSA:3.40.47.10 6 213 2.2E-50 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS31835 70d1756de374fc79de1577ce7ecbc06f 359 SUPERFAMILY SSF53901 80 359 1.28E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS05960 96f3cea842a112a8907ff7d53ef8d883 177 SMART SM00400 79 129 2.6E-5 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SMD11_RS05960 96f3cea842a112a8907ff7d53ef8d883 177 Gene3D G3DSA:3.90.580.10 54 132 1.7E-15 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SMD11_RS05960 96f3cea842a112a8907ff7d53ef8d883 177 SUPERFAMILY SSF57783 53 133 2.38E-16 T 06-07-2017 SMD11_RS05960 96f3cea842a112a8907ff7d53ef8d883 177 Pfam PF01807 CHC2 zinc finger 55 131 1.6E-10 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SMD11_RS18375 4a1f9e6d7600d83521eeab8dac0c7d50 399 Gene3D G3DSA:3.20.20.370 69 377 7.5E-11 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS18375 4a1f9e6d7600d83521eeab8dac0c7d50 399 SUPERFAMILY SSF88713 145 377 2.7E-25 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS18375 4a1f9e6d7600d83521eeab8dac0c7d50 399 SUPERFAMILY SSF88713 71 115 2.7E-25 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS28530 35388427364976bb439977edb255c237 253 SUPERFAMILY SSF51161 70 216 1.18E-33 T 06-07-2017 IPR011004 Trimeric LpxA-like SMD11_RS28530 35388427364976bb439977edb255c237 253 Gene3D G3DSA:2.160.10.10 70 216 1.3E-36 T 06-07-2017 SMD11_RS28530 35388427364976bb439977edb255c237 253 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 169 197 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 SMD11_RS28530 35388427364976bb439977edb255c237 253 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 161 195 3.4E-9 T 06-07-2017 IPR001451 Hexapeptide repeat SMD11_RS05655 33daa8f8ddac7d6fffa9494d0cc39790 318 SMART SM00849 44 221 4.5E-7 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS05655 33daa8f8ddac7d6fffa9494d0cc39790 318 Gene3D G3DSA:3.60.15.10 23 179 2.8E-27 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS05655 33daa8f8ddac7d6fffa9494d0cc39790 318 SUPERFAMILY SSF56281 23 179 1.3E-27 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS05655 33daa8f8ddac7d6fffa9494d0cc39790 318 Pfam PF00753 Metallo-beta-lactamase superfamily 41 174 1.1E-9 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS34410 64c311c947451fb16c8097ec7f33df7d 331 Gene3D G3DSA:3.40.50.150 82 330 1.4E-67 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS34410 64c311c947451fb16c8097ec7f33df7d 331 SUPERFAMILY SSF53335 76 297 5.33E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS34410 64c311c947451fb16c8097ec7f33df7d 331 Pfam PF04672 S-adenosyl methyltransferase 81 314 1.7E-60 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD11_RS34195 b88ada5594dc149cf1e4811963a2d0f9 147 Gene3D G3DSA:3.40.1400.10 13 144 9.5E-40 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMD11_RS34195 b88ada5594dc149cf1e4811963a2d0f9 147 SUPERFAMILY SSF89623 10 144 1.27E-37 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMD11_RS34195 b88ada5594dc149cf1e4811963a2d0f9 147 Pfam PF02502 Ribose/Galactose Isomerase 15 134 3.1E-32 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMD11_RS34195 b88ada5594dc149cf1e4811963a2d0f9 147 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 15 129 5.0E-28 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMD11_RS34195 b88ada5594dc149cf1e4811963a2d0f9 147 PIRSF PIRSF005384 1 147 4.3E-36 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SMD11_RS27405 41d2d2047fab8955761745638f4fdc40 720 SUPERFAMILY SSF52540 236 309 8.75E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27405 41d2d2047fab8955761745638f4fdc40 720 Gene3D G3DSA:3.40.50.300 233 333 1.4E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27405 41d2d2047fab8955761745638f4fdc40 720 Hamap MF_00983 Probable primosomal protein N' [priA]. 61 719 20.385 T 06-07-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 SMD11_RS06410 163ead162ed1c10d093bb455342b4dd6 330 SUPERFAMILY SSF55729 127 260 1.11E-9 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS06410 163ead162ed1c10d093bb455342b4dd6 330 SUPERFAMILY SSF55729 291 306 1.11E-9 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS06410 163ead162ed1c10d093bb455342b4dd6 330 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 13 311 2.7E-66 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal SMD11_RS32215 238fa44c0e8bbb8e770ea6b884c0a2a9 167 SUPERFAMILY SSF50370 30 161 7.27E-30 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS32215 238fa44c0e8bbb8e770ea6b884c0a2a9 167 SMART SM00458 27 163 1.5E-8 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS32215 238fa44c0e8bbb8e770ea6b884c0a2a9 167 Gene3D G3DSA:2.80.10.50 32 162 5.8E-21 T 06-07-2017 SMD11_RS32215 238fa44c0e8bbb8e770ea6b884c0a2a9 167 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 32 103 2.2E-15 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS32345 27bd1a6df66eb4c25c36a72cbf054a35 311 SMART SM00382 26 209 9.4E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS32345 27bd1a6df66eb4c25c36a72cbf054a35 311 Pfam PF00005 ABC transporter 17 160 1.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS32345 27bd1a6df66eb4c25c36a72cbf054a35 311 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 9 302 1.7E-96 T 06-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMD11_RS32345 27bd1a6df66eb4c25c36a72cbf054a35 311 SUPERFAMILY SSF52540 2 223 2.98E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS32345 27bd1a6df66eb4c25c36a72cbf054a35 311 Gene3D G3DSA:3.40.50.300 1 227 1.5E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08855 ee487fd2aacedb5030d4681a9d82d63c 709 Gene3D G3DSA:3.10.20.30 427 489 4.9E-12 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS08855 ee487fd2aacedb5030d4681a9d82d63c 709 SMART SM00471 80 190 1.3E-11 T 06-07-2017 IPR003607 HD/PDEase domain SMD11_RS08855 ee487fd2aacedb5030d4681a9d82d63c 709 SUPERFAMILY SSF55021 625 699 6.35E-6 T 06-07-2017 SMD11_RS08855 ee487fd2aacedb5030d4681a9d82d63c 709 SUPERFAMILY SSF81301 229 373 9.32E-31 T 06-07-2017 SMD11_RS08855 ee487fd2aacedb5030d4681a9d82d63c 709 Pfam PF04607 Region found in RelA / SpoT proteins 294 366 2.2E-12 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 SMD11_RS08855 ee487fd2aacedb5030d4681a9d82d63c 709 SUPERFAMILY SSF109604 44 228 1.13E-61 T 06-07-2017 SMD11_RS08855 ee487fd2aacedb5030d4681a9d82d63c 709 Gene3D G3DSA:3.30.70.260 625 698 5.9E-8 T 06-07-2017 SMD11_RS08855 ee487fd2aacedb5030d4681a9d82d63c 709 Gene3D G3DSA:3.30.460.10 247 359 3.1E-20 T 06-07-2017 SMD11_RS08855 ee487fd2aacedb5030d4681a9d82d63c 709 Pfam PF02824 TGS domain 428 486 2.5E-13 T 06-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 SMD11_RS08855 ee487fd2aacedb5030d4681a9d82d63c 709 Pfam PF13291 ACT domain 624 699 1.9E-13 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 SMD11_RS08855 ee487fd2aacedb5030d4681a9d82d63c 709 SMART SM00954 271 379 5.0E-24 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 SMD11_RS08855 ee487fd2aacedb5030d4681a9d82d63c 709 Pfam PF13328 HD domain 65 212 3.6E-39 T 06-07-2017 IPR003607 HD/PDEase domain SMD11_RS08855 ee487fd2aacedb5030d4681a9d82d63c 709 SUPERFAMILY SSF81271 428 485 5.89E-9 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SMD11_RS15055 d801e103774f35e4015c79eb0020e6d3 78 SUPERFAMILY SSF143800 2 76 1.2E-25 T 06-07-2017 SMD11_RS15055 d801e103774f35e4015c79eb0020e6d3 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 5.0E-27 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS15055 d801e103774f35e4015c79eb0020e6d3 78 Gene3D G3DSA:2.30.170.40 2 77 4.1E-31 T 06-07-2017 SMD11_RS15055 d801e103774f35e4015c79eb0020e6d3 78 Pfam PF00830 Ribosomal L28 family 4 60 5.3E-24 T 06-07-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS15055 d801e103774f35e4015c79eb0020e6d3 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 71 20.476 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS07780 36c4614d9126f4796f2daa66805ec5cd 307 SUPERFAMILY SSF52151 1 117 2.28E-61 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS07780 36c4614d9126f4796f2daa66805ec5cd 307 SUPERFAMILY SSF52151 185 305 2.28E-61 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS07780 36c4614d9126f4796f2daa66805ec5cd 307 SUPERFAMILY SSF55048 124 191 4.32E-16 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS07780 36c4614d9126f4796f2daa66805ec5cd 307 PIRSF PIRSF000446 1 306 1.1E-81 T 06-07-2017 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 SMD11_RS07780 36c4614d9126f4796f2daa66805ec5cd 307 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1 304 4.0E-39 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS07780 36c4614d9126f4796f2daa66805ec5cd 307 Gene3D G3DSA:3.30.70.250 123 191 1.7E-24 T 06-07-2017 SMD11_RS07780 36c4614d9126f4796f2daa66805ec5cd 307 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 284 1.6E-82 T 06-07-2017 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 SMD11_RS07780 36c4614d9126f4796f2daa66805ec5cd 307 Gene3D G3DSA:3.40.366.10 192 297 2.8E-61 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS07780 36c4614d9126f4796f2daa66805ec5cd 307 Gene3D G3DSA:3.40.366.10 1 117 2.8E-61 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS07780 36c4614d9126f4796f2daa66805ec5cd 307 Pfam PF00698 Acyl transferase domain 2 276 6.4E-37 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS00930 ddea1523c476551e4a3f19fecf73e34d 269 Gene3D G3DSA:3.40.50.720 16 262 4.6E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00930 ddea1523c476551e4a3f19fecf73e34d 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 1.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00930 ddea1523c476551e4a3f19fecf73e34d 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 1.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00930 ddea1523c476551e4a3f19fecf73e34d 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 1.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00930 ddea1523c476551e4a3f19fecf73e34d 269 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS00930 ddea1523c476551e4a3f19fecf73e34d 269 SUPERFAMILY SSF51735 16 262 1.87E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS00930 ddea1523c476551e4a3f19fecf73e34d 269 Pfam PF00106 short chain dehydrogenase 17 206 1.1E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00930 ddea1523c476551e4a3f19fecf73e34d 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 1.8E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00930 ddea1523c476551e4a3f19fecf73e34d 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.8E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00930 ddea1523c476551e4a3f19fecf73e34d 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.8E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00930 ddea1523c476551e4a3f19fecf73e34d 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.8E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS00930 ddea1523c476551e4a3f19fecf73e34d 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.8E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS23625 8b596793f314e6e4e2ae3bdd17e257b7 400 Gene3D G3DSA:3.40.50.1240 196 400 7.2E-55 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS23625 8b596793f314e6e4e2ae3bdd17e257b7 400 SUPERFAMILY SSF53254 196 399 5.37E-52 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS23625 8b596793f314e6e4e2ae3bdd17e257b7 400 Pfam PF13456 Reverse transcriptase-like 10 131 3.7E-19 T 06-07-2017 SMD11_RS23625 8b596793f314e6e4e2ae3bdd17e257b7 400 Gene3D G3DSA:3.30.420.10 3 134 1.1E-22 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS23625 8b596793f314e6e4e2ae3bdd17e257b7 400 SMART SM00855 198 355 4.7E-16 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS23625 8b596793f314e6e4e2ae3bdd17e257b7 400 PIRSF PIRSF036922 1 400 9.1E-178 T 06-07-2017 IPR014636 RNase H, phosphoglycerate mutase domain-containing SMD11_RS23625 8b596793f314e6e4e2ae3bdd17e257b7 400 SUPERFAMILY SSF53098 4 130 7.97E-31 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS23625 8b596793f314e6e4e2ae3bdd17e257b7 400 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 199 395 1.5E-56 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS31330 042ebfbbda61744d3fdcb74f67c1c97f 289 Gene3D G3DSA:1.10.1040.10 192 287 2.1E-32 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS31330 042ebfbbda61744d3fdcb74f67c1c97f 289 SUPERFAMILY SSF51735 6 187 4.4E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS31330 042ebfbbda61744d3fdcb74f67c1c97f 289 SUPERFAMILY SSF48179 190 288 1.7E-30 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS31330 042ebfbbda61744d3fdcb74f67c1c97f 289 Gene3D G3DSA:3.40.50.720 7 191 2.0E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS31330 042ebfbbda61744d3fdcb74f67c1c97f 289 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 286 3.6E-30 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS31330 042ebfbbda61744d3fdcb74f67c1c97f 289 PIRSF PIRSF000105 2 289 8.1E-80 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 SMD11_RS31330 042ebfbbda61744d3fdcb74f67c1c97f 289 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 187 2.3E-55 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS30960 5ec6ae22c59ef055cf31690645664e5c 341 Pfam PF13469 Sulfotransferase family 6 36 1.1E-6 T 06-07-2017 SMD11_RS30960 5ec6ae22c59ef055cf31690645664e5c 341 Gene3D G3DSA:3.40.50.300 134 299 6.0E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30960 5ec6ae22c59ef055cf31690645664e5c 341 Gene3D G3DSA:3.40.50.300 6 56 6.0E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30960 5ec6ae22c59ef055cf31690645664e5c 341 SUPERFAMILY SSF52540 238 303 2.01E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30960 5ec6ae22c59ef055cf31690645664e5c 341 SUPERFAMILY SSF52540 4 37 2.01E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30960 5ec6ae22c59ef055cf31690645664e5c 341 SUPERFAMILY SSF52540 143 193 2.01E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS13205 22cdfb5290219e0e754fb18535f5bc6b 136 Pfam PF11222 Protein of unknown function (DUF3017) 45 115 1.9E-21 T 06-07-2017 IPR021385 Protein of unknown function DUF3017 SMD11_RS18055 9563d816da344969218d1f45eab1eca5 146 SUPERFAMILY SSF46785 5 140 7.8E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS18055 9563d816da344969218d1f45eab1eca5 146 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site SMD11_RS18055 9563d816da344969218d1f45eab1eca5 146 Pfam PF01047 MarR family 35 90 3.4E-17 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS18055 9563d816da344969218d1f45eab1eca5 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 2.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS18055 9563d816da344969218d1f45eab1eca5 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 2.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS18055 9563d816da344969218d1f45eab1eca5 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 2.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS18055 9563d816da344969218d1f45eab1eca5 146 Gene3D G3DSA:1.10.10.10 4 140 3.5E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS18055 9563d816da344969218d1f45eab1eca5 146 SMART SM00347 25 125 5.2E-25 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS29095 3a6458ed7dec672325f58d22353567c9 538 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS29095 3a6458ed7dec672325f58d22353567c9 538 Gene3D G3DSA:2.30.38.10 363 432 1.1E-11 T 06-07-2017 SMD11_RS29095 3a6458ed7dec672325f58d22353567c9 538 SUPERFAMILY SSF56801 4 537 1.57E-114 T 06-07-2017 SMD11_RS29095 3a6458ed7dec672325f58d22353567c9 538 Gene3D G3DSA:3.40.50.980 184 351 4.4E-20 T 06-07-2017 SMD11_RS29095 3a6458ed7dec672325f58d22353567c9 538 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 524 4.9E-19 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS29095 3a6458ed7dec672325f58d22353567c9 538 Pfam PF00501 AMP-binding enzyme 9 438 4.4E-61 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS29095 3a6458ed7dec672325f58d22353567c9 538 Gene3D G3DSA:3.30.300.30 436 533 1.3E-29 T 06-07-2017 SMD11_RS29095 3a6458ed7dec672325f58d22353567c9 538 Gene3D G3DSA:3.40.50.980 4 183 4.9E-35 T 06-07-2017 SMD11_RS26130 1c7efff6c628d2357d90bdd421caf1e4 354 Gene3D G3DSA:3.90.550.10 8 234 2.7E-32 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS26130 1c7efff6c628d2357d90bdd421caf1e4 354 Pfam PF00535 Glycosyl transferase family 2 10 178 8.4E-21 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD11_RS26130 1c7efff6c628d2357d90bdd421caf1e4 354 SUPERFAMILY SSF53448 5 239 1.41E-39 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS22760 3c4ac6edb985c8909b605fde79ef7393 389 Gene3D G3DSA:3.40.1190.20 50 348 2.3E-56 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS22760 3c4ac6edb985c8909b605fde79ef7393 389 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 288 301 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMD11_RS22760 3c4ac6edb985c8909b605fde79ef7393 389 Pfam PF00294 pfkB family carbohydrate kinase 77 335 1.4E-31 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB SMD11_RS22760 3c4ac6edb985c8909b605fde79ef7393 389 SUPERFAMILY SSF53613 50 344 8.11E-51 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS25955 1c38658115742a1118dcaa845c35c701 548 Gene3D G3DSA:1.20.1250.20 42 222 1.0E-28 T 06-07-2017 SMD11_RS25955 1c38658115742a1118dcaa845c35c701 548 Gene3D G3DSA:1.20.1250.20 296 451 8.8E-18 T 06-07-2017 SMD11_RS25955 1c38658115742a1118dcaa845c35c701 548 Gene3D G3DSA:1.20.1250.20 503 527 8.8E-18 T 06-07-2017 SMD11_RS25955 1c38658115742a1118dcaa845c35c701 548 SUPERFAMILY SSF103473 29 227 3.66E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS25955 1c38658115742a1118dcaa845c35c701 548 SUPERFAMILY SSF103473 279 450 3.66E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS25955 1c38658115742a1118dcaa845c35c701 548 SUPERFAMILY SSF103473 502 527 3.66E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS25955 1c38658115742a1118dcaa845c35c701 548 Pfam PF07690 Major Facilitator Superfamily 48 440 1.6E-46 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS25955 1c38658115742a1118dcaa845c35c701 548 PRINTS PR01036 Tetracycline resistance protein TetB signature 46 70 1.2E-9 T 06-07-2017 SMD11_RS25955 1c38658115742a1118dcaa845c35c701 548 PRINTS PR01036 Tetracycline resistance protein TetB signature 168 192 1.2E-9 T 06-07-2017 SMD11_RS25955 1c38658115742a1118dcaa845c35c701 548 PRINTS PR01036 Tetracycline resistance protein TetB signature 333 357 1.2E-9 T 06-07-2017 SMD11_RS25955 1c38658115742a1118dcaa845c35c701 548 PRINTS PR01036 Tetracycline resistance protein TetB signature 431 450 1.2E-9 T 06-07-2017 SMD11_RS25955 1c38658115742a1118dcaa845c35c701 548 PRINTS PR01036 Tetracycline resistance protein TetB signature 106 128 1.2E-9 T 06-07-2017 SMD11_RS31045 95dc6ae2608ccdf306f99e06945e393a 382 Gene3D G3DSA:3.40.630.30 159 297 1.2E-7 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS31045 95dc6ae2608ccdf306f99e06945e393a 382 SUPERFAMILY SSF55729 153 296 6.64E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS17380 b19fb9448df95314cf1b99720aea011b 184 Pfam PF00583 Acetyltransferase (GNAT) family 63 128 1.0E-4 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS17380 b19fb9448df95314cf1b99720aea011b 184 Gene3D G3DSA:3.40.630.30 17 168 8.3E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS17380 b19fb9448df95314cf1b99720aea011b 184 SUPERFAMILY SSF55729 3 128 2.24E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS16900 1d592a8ea034fd64128c6db868915168 45 Pfam PF00468 Ribosomal protein L34 3 45 8.8E-20 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16900 1d592a8ea034fd64128c6db868915168 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.605 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16900 1d592a8ea034fd64128c6db868915168 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 40 1.0E-13 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16900 1d592a8ea034fd64128c6db868915168 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 1.7E-19 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS16900 1d592a8ea034fd64128c6db868915168 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 06-07-2017 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS31870 1e98b033dc5d15067119b60a16b7d3f3 460 Pfam PF00027 Cyclic nucleotide-binding domain 102 188 6.6E-12 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain SMD11_RS31870 1e98b033dc5d15067119b60a16b7d3f3 460 SUPERFAMILY SSF51206 73 193 1.31E-19 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like SMD11_RS31870 1e98b033dc5d15067119b60a16b7d3f3 460 SMART SM00100 83 204 2.0E-6 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain SMD11_RS31870 1e98b033dc5d15067119b60a16b7d3f3 460 Gene3D G3DSA:2.60.120.10 77 199 3.0E-16 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS33515 bdd02072a574ff988168830e047df5d1 444 SUPERFAMILY SSF103473 5 409 1.83E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS33515 bdd02072a574ff988168830e047df5d1 444 Gene3D G3DSA:1.20.1250.20 226 407 6.5E-17 T 06-07-2017 SMD11_RS33515 bdd02072a574ff988168830e047df5d1 444 Gene3D G3DSA:1.20.1250.20 14 199 7.5E-18 T 06-07-2017 SMD11_RS33515 bdd02072a574ff988168830e047df5d1 444 Pfam PF07690 Major Facilitator Superfamily 17 373 2.9E-28 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS29500 3a6b73ffaabd5a8ead90921b0d8f997c 710 SMART SM01008 27 131 9.4E-25 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS29500 3a6b73ffaabd5a8ead90921b0d8f997c 710 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 157 644 5.8E-108 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS29500 3a6b73ffaabd5a8ead90921b0d8f997c 710 Gene3D G3DSA:3.30.365.10 351 446 1.0E-53 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS29500 3a6b73ffaabd5a8ead90921b0d8f997c 710 Gene3D G3DSA:3.30.365.10 571 704 1.0E-53 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS29500 3a6b73ffaabd5a8ead90921b0d8f997c 710 SUPERFAMILY SSF56003 148 704 3.66E-149 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS29500 3a6b73ffaabd5a8ead90921b0d8f997c 710 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 27 129 5.2E-13 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS29500 3a6b73ffaabd5a8ead90921b0d8f997c 710 Gene3D G3DSA:3.30.365.10 447 570 2.1E-23 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS29500 3a6b73ffaabd5a8ead90921b0d8f997c 710 SUPERFAMILY SSF54665 17 134 6.28E-28 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS29500 3a6b73ffaabd5a8ead90921b0d8f997c 710 Gene3D G3DSA:3.30.365.10 278 348 2.9E-6 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS29500 3a6b73ffaabd5a8ead90921b0d8f997c 710 Gene3D G3DSA:3.30.365.10 147 170 2.9E-6 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS29500 3a6b73ffaabd5a8ead90921b0d8f997c 710 Gene3D G3DSA:3.90.1170.50 18 129 7.9E-23 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS29500 3a6b73ffaabd5a8ead90921b0d8f997c 710 Gene3D G3DSA:3.30.365.10 171 271 9.7E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS03135 1caeb9d6d337e24444472531f9cd5634 374 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 45 334 3.8E-48 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS03135 1caeb9d6d337e24444472531f9cd5634 374 Gene3D G3DSA:3.40.50.1100 163 354 4.7E-35 T 06-07-2017 SMD11_RS03135 1caeb9d6d337e24444472531f9cd5634 374 Gene3D G3DSA:3.40.50.1100 66 162 9.7E-24 T 06-07-2017 SMD11_RS03135 1caeb9d6d337e24444472531f9cd5634 374 SUPERFAMILY SSF53686 42 355 1.96E-69 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS28065 43203ec0858554c545a4aa76d993db9f 155 SUPERFAMILY SSF103196 24 148 1.57E-34 T 06-07-2017 SMD11_RS28065 43203ec0858554c545a4aa76d993db9f 155 Gene3D G3DSA:3.30.450.30 27 145 7.2E-25 T 06-07-2017 SMD11_RS28065 43203ec0858554c545a4aa76d993db9f 155 Pfam PF03259 Roadblock/LC7 domain 29 119 1.3E-25 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS28065 43203ec0858554c545a4aa76d993db9f 155 SMART SM00960 29 119 1.1E-28 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS04120 ecb2786cf097e25ba4ac6f86d5a89ca9 475 Pfam PF00027 Cyclic nucleotide-binding domain 120 205 3.9E-15 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain SMD11_RS04120 ecb2786cf097e25ba4ac6f86d5a89ca9 475 SMART SM00100 100 223 3.4E-11 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain SMD11_RS04120 ecb2786cf097e25ba4ac6f86d5a89ca9 475 SUPERFAMILY SSF51206 95 227 7.34E-23 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like SMD11_RS04120 ecb2786cf097e25ba4ac6f86d5a89ca9 475 Gene3D G3DSA:2.60.120.10 95 228 9.5E-23 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS03815 305bc479615f4207e2d979b56251eb7d 223 Pfam PF08713 DNA alkylation repair enzyme 9 187 1.9E-20 T 06-07-2017 IPR014825 DNA alkylation repair enzyme SMD11_RS03815 305bc479615f4207e2d979b56251eb7d 223 SUPERFAMILY SSF48371 6 221 1.18E-61 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 SMD11_RS26220 b97ef65f88be83abcd2e69fff3aaa7ce 480 Pfam PF01425 Amidase 25 459 2.0E-107 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS26220 b97ef65f88be83abcd2e69fff3aaa7ce 480 SUPERFAMILY SSF75304 2 469 6.93E-127 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS26220 b97ef65f88be83abcd2e69fff3aaa7ce 480 Gene3D G3DSA:3.90.1300.10 2 477 9.3E-127 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS26220 b97ef65f88be83abcd2e69fff3aaa7ce 480 ProSitePatterns PS00571 Amidases signature. 157 188 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMD11_RS21685 840ad642db14fc4bd2e78e56d687b9de 201 SUPERFAMILY SSF53098 3 177 6.28E-41 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS21685 840ad642db14fc4bd2e78e56d687b9de 201 Pfam PF00929 Exonuclease 6 168 1.5E-24 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD11_RS21685 840ad642db14fc4bd2e78e56d687b9de 201 Gene3D G3DSA:3.30.420.10 1 177 9.2E-68 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS21685 840ad642db14fc4bd2e78e56d687b9de 201 Hamap MF_00045 Oligoribonuclease [orn]. 1 179 37.876 T 06-07-2017 IPR022894 Oligoribonuclease GO:0016788 SMD11_RS21685 840ad642db14fc4bd2e78e56d687b9de 201 SMART SM00479 4 178 5.4E-22 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD11_RS30230 32bff16829c6d32c2b4ef88a20ecf3d5 334 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 135 202 1.0E-9 T 06-07-2017 SMD11_RS30230 32bff16829c6d32c2b4ef88a20ecf3d5 334 SUPERFAMILY SSF69318 70 319 5.36E-32 T 06-07-2017 SMD11_RS30230 32bff16829c6d32c2b4ef88a20ecf3d5 334 Gene3D G3DSA:2.130.10.130 36 317 9.8E-22 T 06-07-2017 SMD11_RS05410 dfb7136e19708ab6af3338d804311906 251 Gene3D G3DSA:3.90.226.10 3 246 2.1E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS05410 dfb7136e19708ab6af3338d804311906 251 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 246 7.0E-44 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS05410 dfb7136e19708ab6af3338d804311906 251 SUPERFAMILY SSF52096 4 246 3.05E-68 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS07255 01bae54324948a3dd5f03a7a231df933 333 Gene3D G3DSA:3.90.1200.10 143 299 5.6E-12 T 06-07-2017 SMD11_RS07255 01bae54324948a3dd5f03a7a231df933 333 Pfam PF01636 Phosphotransferase enzyme family 83 281 1.8E-15 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase SMD11_RS07255 01bae54324948a3dd5f03a7a231df933 333 SUPERFAMILY SSF56112 47 304 1.9E-32 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS25225 bdc82d2d6abe1dac6fe7ce7766a13e6a 255 Pfam PF00005 ABC transporter 23 174 5.0E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS25225 bdc82d2d6abe1dac6fe7ce7766a13e6a 255 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 245 6.1E-103 T 06-07-2017 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 SMD11_RS25225 bdc82d2d6abe1dac6fe7ce7766a13e6a 255 SMART SM00382 32 226 1.2E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS25225 bdc82d2d6abe1dac6fe7ce7766a13e6a 255 Gene3D G3DSA:3.40.50.300 3 234 6.6E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25225 bdc82d2d6abe1dac6fe7ce7766a13e6a 255 SUPERFAMILY SSF52540 4 234 6.55E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01705 13f7444be225bb46c116005f04c68417 377 SUPERFAMILY SSF51905 269 354 1.94E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01705 13f7444be225bb46c116005f04c68417 377 SUPERFAMILY SSF51905 8 174 1.94E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01705 13f7444be225bb46c116005f04c68417 377 Pfam PF01494 FAD binding domain 7 345 2.0E-39 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS01705 13f7444be225bb46c116005f04c68417 377 Gene3D G3DSA:3.50.50.60 270 349 3.6E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01705 13f7444be225bb46c116005f04c68417 377 Gene3D G3DSA:3.50.50.60 6 179 3.6E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01705 13f7444be225bb46c116005f04c68417 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 4.5E-22 T 06-07-2017 SMD11_RS01705 13f7444be225bb46c116005f04c68417 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 4.5E-22 T 06-07-2017 SMD11_RS01705 13f7444be225bb46c116005f04c68417 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 4.5E-22 T 06-07-2017 SMD11_RS01705 13f7444be225bb46c116005f04c68417 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 331 347 4.5E-22 T 06-07-2017 SMD11_RS01705 13f7444be225bb46c116005f04c68417 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 4.5E-22 T 06-07-2017 SMD11_RS05090 9722dfe60759fafb3b8984ef524c0ae6 371 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 3 361 1.0E-139 T 06-07-2017 IPR002780 Hydrogenase formation HypD protein GO:0046872 SMD11_RS05090 9722dfe60759fafb3b8984ef524c0ae6 371 Pfam PF01924 Hydrogenase formation hypA family 12 357 1.3E-145 T 06-07-2017 IPR002780 Hydrogenase formation HypD protein GO:0046872 SMD11_RS05090 9722dfe60759fafb3b8984ef524c0ae6 371 PIRSF PIRSF005622 1 364 8.7E-147 T 06-07-2017 IPR002780 Hydrogenase formation HypD protein GO:0046872 SMD11_RS19555 c30e1fcb884d32684e01ad9c117f10b4 256 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 8 202 5.5E-47 T 06-07-2017 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 SMD11_RS19555 c30e1fcb884d32684e01ad9c117f10b4 256 Gene3D G3DSA:1.10.3630.10 3 216 5.5E-41 T 06-07-2017 SMD11_RS30545 cff52c00bfaaf1f4b50b8e8d9aeec85a 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 6.3E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS30545 cff52c00bfaaf1f4b50b8e8d9aeec85a 314 Gene3D G3DSA:3.40.190.10 88 177 1.9E-24 T 06-07-2017 SMD11_RS30545 cff52c00bfaaf1f4b50b8e8d9aeec85a 314 SUPERFAMILY SSF53850 88 298 7.06E-32 T 06-07-2017 SMD11_RS30545 cff52c00bfaaf1f4b50b8e8d9aeec85a 314 Gene3D G3DSA:3.40.190.10 178 266 2.2E-10 T 06-07-2017 SMD11_RS30545 cff52c00bfaaf1f4b50b8e8d9aeec85a 314 SUPERFAMILY SSF46785 1 80 2.64E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30545 cff52c00bfaaf1f4b50b8e8d9aeec85a 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS30545 cff52c00bfaaf1f4b50b8e8d9aeec85a 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS30545 cff52c00bfaaf1f4b50b8e8d9aeec85a 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS30545 cff52c00bfaaf1f4b50b8e8d9aeec85a 314 Pfam PF03466 LysR substrate binding domain 87 294 8.3E-31 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS30545 cff52c00bfaaf1f4b50b8e8d9aeec85a 314 Gene3D G3DSA:1.10.10.10 1 83 3.2E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02730 90ed04879389c1d08e6098bda946d8ac 179 Pfam PF14016 Protein of unknown function (DUF4232) 41 172 8.4E-25 T 06-07-2017 IPR025326 Protein of unknown function DUF4232 SMD11_RS24030 9abcee7cfad7b889a96fdff7fcfb2437 321 Pfam PF04055 Radical SAM superfamily 82 241 5.0E-11 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS24030 9abcee7cfad7b889a96fdff7fcfb2437 321 Gene3D G3DSA:3.20.20.70 39 307 6.1E-62 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS24030 9abcee7cfad7b889a96fdff7fcfb2437 321 PIRSF PIRSF005963 3 320 2.5E-119 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SMD11_RS24030 9abcee7cfad7b889a96fdff7fcfb2437 321 Hamap MF_00206 Lipoyl synthase [lipA]. 1 313 136.635 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SMD11_RS24030 9abcee7cfad7b889a96fdff7fcfb2437 321 SMART SM00729 72 286 2.1E-11 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD11_RS24030 9abcee7cfad7b889a96fdff7fcfb2437 321 TIGRFAM TIGR00510 lipA: lipoyl synthase 18 311 1.8E-96 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 SMD11_RS24030 9abcee7cfad7b889a96fdff7fcfb2437 321 SUPERFAMILY SSF102114 36 313 3.01E-59 T 06-07-2017 SMD11_RS25335 9e6ba9b8b58141c0cc0d4b2b2ddbd934 361 Pfam PF00266 Aminotransferase class-V 26 308 5.5E-18 T 06-07-2017 IPR000192 Aminotransferase class V domain SMD11_RS25335 9e6ba9b8b58141c0cc0d4b2b2ddbd934 361 Gene3D G3DSA:3.40.640.10 58 273 3.4E-34 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS25335 9e6ba9b8b58141c0cc0d4b2b2ddbd934 361 Gene3D G3DSA:3.90.1150.10 274 359 6.7E-4 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS25335 9e6ba9b8b58141c0cc0d4b2b2ddbd934 361 SUPERFAMILY SSF53383 22 359 3.63E-50 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS02340 36396ce22620240bf529e87be4ee5eba 211 SUPERFAMILY SSF46689 2 77 1.28E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS02340 36396ce22620240bf529e87be4ee5eba 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 1.2E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS02340 36396ce22620240bf529e87be4ee5eba 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 5.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS02340 36396ce22620240bf529e87be4ee5eba 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 5.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS02340 36396ce22620240bf529e87be4ee5eba 211 Gene3D G3DSA:1.10.357.10 2 185 2.3E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS29510 b2e9150308f647d992abc21bb5d98fe3 202 Gene3D G3DSA:1.10.150.120 109 201 2.9E-27 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD11_RS29510 b2e9150308f647d992abc21bb5d98fe3 202 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 40 89 6.6E-7 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS29510 b2e9150308f647d992abc21bb5d98fe3 202 Gene3D G3DSA:3.10.20.30 35 108 2.8E-30 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS29510 b2e9150308f647d992abc21bb5d98fe3 202 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 73 81 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMD11_RS29510 b2e9150308f647d992abc21bb5d98fe3 202 SUPERFAMILY SSF47741 118 201 5.1E-25 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD11_RS29510 b2e9150308f647d992abc21bb5d98fe3 202 SUPERFAMILY SSF54292 36 121 5.51E-25 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS29510 b2e9150308f647d992abc21bb5d98fe3 202 Pfam PF01799 [2Fe-2S] binding domain 107 197 7.2E-27 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD11_RS11200 1830a05a8b3b692f44fee564a5cb509f 303 TIGRFAM TIGR03814 Gln_ase: glutaminase A 7 303 1.2E-121 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 SMD11_RS11200 1830a05a8b3b692f44fee564a5cb509f 303 SUPERFAMILY SSF56601 2 303 1.33E-106 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS11200 1830a05a8b3b692f44fee564a5cb509f 303 Hamap MF_00313 Glutaminase [glsA]. 3 303 45.88 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 SMD11_RS11200 1830a05a8b3b692f44fee564a5cb509f 303 Pfam PF04960 Glutaminase 21 303 2.8E-109 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 SMD11_RS11200 1830a05a8b3b692f44fee564a5cb509f 303 Gene3D G3DSA:3.40.710.10 3 303 4.0E-116 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS19975 40dbb6ac0540de25e80c10fb07116536 301 Pfam PF00106 short chain dehydrogenase 10 198 3.4E-48 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19975 40dbb6ac0540de25e80c10fb07116536 301 Gene3D G3DSA:3.40.50.720 9 239 1.6E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19975 40dbb6ac0540de25e80c10fb07116536 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19975 40dbb6ac0540de25e80c10fb07116536 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19975 40dbb6ac0540de25e80c10fb07116536 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19975 40dbb6ac0540de25e80c10fb07116536 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19975 40dbb6ac0540de25e80c10fb07116536 301 SUPERFAMILY SSF51735 7 258 1.33E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19975 40dbb6ac0540de25e80c10fb07116536 301 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 189 1.0E-4 T 06-07-2017 SMD11_RS19975 40dbb6ac0540de25e80c10fb07116536 301 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS19975 40dbb6ac0540de25e80c10fb07116536 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 4.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19975 40dbb6ac0540de25e80c10fb07116536 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 4.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19975 40dbb6ac0540de25e80c10fb07116536 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS07600 62c27caf6f7b66b8ab3256bff00be634 365 Pfam PF12697 Alpha/beta hydrolase family 118 341 6.4E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS07600 62c27caf6f7b66b8ab3256bff00be634 365 Gene3D G3DSA:3.40.50.1820 86 339 2.3E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS07600 62c27caf6f7b66b8ab3256bff00be634 365 SUPERFAMILY SSF53474 80 339 4.32E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS26295 f0ef63cacf98baf7c34cf44f76e045a7 318 Gene3D G3DSA:1.25.40.10 235 286 2.1E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS26295 f0ef63cacf98baf7c34cf44f76e045a7 318 Gene3D G3DSA:1.25.40.10 55 177 2.1E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS06020 79d0a75a5f7f5158d1256ef60e7dc889 473 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 14 416 5.5E-46 T 06-07-2017 IPR021145 Portal protein, SPP1 Gp6-like SMD11_RS34435 b5c43b083ff1141fa372a1d49181c49f 305 Pfam PF13186 Iron-sulfur cluster-binding domain 205 276 8.6E-7 T 06-07-2017 IPR023885 4Fe4S-binding SPASM domain SMD11_RS34435 b5c43b083ff1141fa372a1d49181c49f 305 Gene3D G3DSA:3.20.20.70 11 270 6.3E-37 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS34435 b5c43b083ff1141fa372a1d49181c49f 305 Pfam PF04055 Radical SAM superfamily 20 161 2.0E-15 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS34435 b5c43b083ff1141fa372a1d49181c49f 305 Pfam PF13353 4Fe-4S single cluster domain 20 84 4.5E-5 T 06-07-2017 SMD11_RS34435 b5c43b083ff1141fa372a1d49181c49f 305 SUPERFAMILY SSF102114 14 251 7.59E-39 T 06-07-2017 SMD11_RS02875 3bca03c5d1b5d995e57cc3b12f8e6f66 444 Gene3D G3DSA:1.20.1250.20 14 190 5.4E-23 T 06-07-2017 SMD11_RS02875 3bca03c5d1b5d995e57cc3b12f8e6f66 444 Gene3D G3DSA:1.20.1250.20 208 402 1.1E-8 T 06-07-2017 SMD11_RS02875 3bca03c5d1b5d995e57cc3b12f8e6f66 444 SUPERFAMILY SSF103473 12 402 2.88E-41 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS02875 3bca03c5d1b5d995e57cc3b12f8e6f66 444 Pfam PF07690 Major Facilitator Superfamily 17 362 5.4E-26 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS03465 159bdf5b8d7946c3452f7625d8990f71 450 PIRSF PIRSF000362 1 448 2.7E-142 T 06-07-2017 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 SMD11_RS03465 159bdf5b8d7946c3452f7625d8990f71 450 Gene3D G3DSA:3.40.50.720 319 442 2.5E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03465 159bdf5b8d7946c3452f7625d8990f71 450 Gene3D G3DSA:3.40.50.720 2 98 2.5E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03465 159bdf5b8d7946c3452f7625d8990f71 450 Gene3D G3DSA:3.50.50.60 99 318 4.2E-68 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03465 159bdf5b8d7946c3452f7625d8990f71 450 PRINTS PR00419 Adrenodoxin reductase family signature 215 228 1.7E-14 T 06-07-2017 SMD11_RS03465 159bdf5b8d7946c3452f7625d8990f71 450 PRINTS PR00419 Adrenodoxin reductase family signature 148 162 1.7E-14 T 06-07-2017 SMD11_RS03465 159bdf5b8d7946c3452f7625d8990f71 450 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 1.7E-14 T 06-07-2017 SMD11_RS03465 159bdf5b8d7946c3452f7625d8990f71 450 PRINTS PR00419 Adrenodoxin reductase family signature 73 83 1.7E-14 T 06-07-2017 SMD11_RS03465 159bdf5b8d7946c3452f7625d8990f71 450 SUPERFAMILY SSF51971 263 319 1.06E-52 T 06-07-2017 SMD11_RS03465 159bdf5b8d7946c3452f7625d8990f71 450 SUPERFAMILY SSF51971 3 214 1.06E-52 T 06-07-2017 SMD11_RS03465 159bdf5b8d7946c3452f7625d8990f71 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 170 1.3E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS14180 88dfa51e603f72f72dd58bea153846c9 229 Gene3D G3DSA:1.20.58.220 1 105 2.7E-28 T 06-07-2017 SMD11_RS14180 88dfa51e603f72f72dd58bea153846c9 229 Gene3D G3DSA:1.20.58.220 116 212 2.5E-21 T 06-07-2017 SMD11_RS14180 88dfa51e603f72f72dd58bea153846c9 229 Pfam PF01895 PhoU domain 121 204 3.1E-13 T 06-07-2017 IPR026022 PhoU domain SMD11_RS14180 88dfa51e603f72f72dd58bea153846c9 229 Pfam PF01895 PhoU domain 16 103 7.4E-17 T 06-07-2017 IPR026022 PhoU domain SMD11_RS14180 88dfa51e603f72f72dd58bea153846c9 229 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 2.5E-57 T 06-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 SMD11_RS14180 88dfa51e603f72f72dd58bea153846c9 229 SUPERFAMILY SSF109755 2 216 2.09E-58 T 06-07-2017 SMD11_RS14180 88dfa51e603f72f72dd58bea153846c9 229 PIRSF PIRSF003107 1 216 2.4E-54 T 06-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 SMD11_RS20020 2124abbc6d87d40d8e41cdd5f11b762a 257 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 22 215 1.9E-48 T 06-07-2017 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 SMD11_RS20020 2124abbc6d87d40d8e41cdd5f11b762a 257 Pfam PF02361 Cobalt transport protein 15 219 7.6E-31 T 06-07-2017 IPR003339 ABC/ECF transporter, transmembrane component SMD11_RS23125 6a3497068d4f7c34f3bae7336cb2fd98 241 SUPERFAMILY SSF56317 1 240 8.63E-47 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS23125 6a3497068d4f7c34f3bae7336cb2fd98 241 Pfam PF00795 Carbon-nitrogen hydrolase 3 240 3.7E-28 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS23125 6a3497068d4f7c34f3bae7336cb2fd98 241 Gene3D G3DSA:3.60.110.10 2 240 1.7E-45 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS18810 c9b8c29ac5cba2b7da68aad0a62dd5dd 96 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 43 93 1.6E-17 T 06-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD11_RS18810 c9b8c29ac5cba2b7da68aad0a62dd5dd 96 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 42 96 9.7E-21 T 06-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 SMD11_RS18810 c9b8c29ac5cba2b7da68aad0a62dd5dd 96 Hamap MF_00422 Protein translocase subunit SecE [secE]. 38 93 12.747 T 06-07-2017 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD11_RS18810 c9b8c29ac5cba2b7da68aad0a62dd5dd 96 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 43 71 - T 06-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SMD11_RS18810 c9b8c29ac5cba2b7da68aad0a62dd5dd 96 Gene3D G3DSA:1.20.5.1030 37 95 3.2E-21 T 06-07-2017 SMD11_RS26215 67216a0b405f66b1aaec2b061e040067 153 SUPERFAMILY SSF46955 11 132 4.4E-28 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS26215 67216a0b405f66b1aaec2b061e040067 153 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 10 150 4.6E-71 T 06-07-2017 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 SMD11_RS26215 67216a0b405f66b1aaec2b061e040067 153 Gene3D G3DSA:1.10.1660.10 11 64 1.3E-19 T 06-07-2017 SMD11_RS26215 67216a0b405f66b1aaec2b061e040067 153 SMART SM00422 11 79 1.5E-24 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS26215 67216a0b405f66b1aaec2b061e040067 153 Pfam PF00376 MerR family regulatory protein 12 48 7.8E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS26215 67216a0b405f66b1aaec2b061e040067 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 4.3E-13 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS26215 67216a0b405f66b1aaec2b061e040067 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 4.3E-13 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS26215 67216a0b405f66b1aaec2b061e040067 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 4.3E-13 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS26215 67216a0b405f66b1aaec2b061e040067 153 Gene3D G3DSA:1.10.1660.10 65 140 1.6E-17 T 06-07-2017 SMD11_RS26215 67216a0b405f66b1aaec2b061e040067 153 Pfam PF09278 MerR, DNA binding 53 118 3.4E-20 T 06-07-2017 IPR015358 Transcription regulator MerR, DNA binding SMD11_RS13100 ff17ce7c2b947f7400ddedb082699d63 310 PIRSF PIRSF035875 12 299 5.6E-26 T 06-07-2017 IPR017039 Virulence factor BrkB SMD11_RS13100 ff17ce7c2b947f7400ddedb082699d63 310 Pfam PF03631 Virulence factor BrkB 33 276 7.8E-47 T 06-07-2017 IPR017039 Virulence factor BrkB SMD11_RS26850 2bd77420cb80e1aea6119ac8b93ff2ce 279 Pfam PF09948 Predicted metal-binding integral membrane protein (DUF2182) 76 263 4.0E-51 T 06-07-2017 IPR018688 Protein of unknown function DUF2182, transmembrane, metal-binding SMD11_RS23585 581cd2899026954ec5be97bacc6db662 383 Pfam PF07730 Histidine kinase 183 249 3.2E-15 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS23585 581cd2899026954ec5be97bacc6db662 383 Gene3D G3DSA:3.30.565.10 249 373 2.8E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS23585 581cd2899026954ec5be97bacc6db662 383 SUPERFAMILY SSF55874 256 372 1.31E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS05220 8928ab686ac6412a42f7e52e0693af60 401 SUPERFAMILY SSF56349 85 375 1.18E-39 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD11_RS05220 8928ab686ac6412a42f7e52e0693af60 401 Gene3D G3DSA:1.10.443.10 207 372 3.5E-28 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS05220 8928ab686ac6412a42f7e52e0693af60 401 Pfam PF00589 Phage integrase family 219 371 8.5E-16 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS05220 8928ab686ac6412a42f7e52e0693af60 401 Gene3D G3DSA:1.10.150.130 87 169 1.2E-7 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal SMD11_RS26240 360bcd9d706a3a5b1c5f9e70a3e051fd 423 Pfam PF07075 Protein of unknown function (DUF1343) 65 423 1.0E-120 T 06-07-2017 IPR008302 Uncharacterised conserved protein UCP016719 SMD11_RS26240 360bcd9d706a3a5b1c5f9e70a3e051fd 423 PIRSF PIRSF016719 16 423 8.6E-134 T 06-07-2017 IPR008302 Uncharacterised conserved protein UCP016719 SMD11_RS03615 ed9466d32e588237f00b9c601718ebcf 198 Gene3D G3DSA:3.40.50.150 7 149 2.4E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS03615 ed9466d32e588237f00b9c601718ebcf 198 SUPERFAMILY SSF53335 8 185 2.25E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS03615 ed9466d32e588237f00b9c601718ebcf 198 Pfam PF08241 Methyltransferase domain 46 141 4.4E-21 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS13095 4819afefa0e82397fbec2a919bf6eeff 651 SUPERFAMILY SSF56601 256 277 7.15E-46 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS13095 4819afefa0e82397fbec2a919bf6eeff 651 SUPERFAMILY SSF56601 317 572 7.15E-46 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS13095 4819afefa0e82397fbec2a919bf6eeff 651 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 314 551 2.8E-34 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SMD11_RS13095 4819afefa0e82397fbec2a919bf6eeff 651 Gene3D G3DSA:3.40.710.10 314 572 7.6E-67 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS28900 0a0f8965817e91bc158239f832c1da17 932 Pfam PF00196 Bacterial regulatory proteins, luxR family 870 922 8.8E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28900 0a0f8965817e91bc158239f832c1da17 932 SMART SM00421 867 924 1.1E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28900 0a0f8965817e91bc158239f832c1da17 932 Gene3D G3DSA:1.10.10.10 866 924 1.7E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28900 0a0f8965817e91bc158239f832c1da17 932 SUPERFAMILY SSF46894 863 923 1.16E-13 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS28900 0a0f8965817e91bc158239f832c1da17 932 Pfam PF13191 AAA ATPase domain 27 171 7.0E-18 T 06-07-2017 SMD11_RS28900 0a0f8965817e91bc158239f832c1da17 932 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 884 900 8.7E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28900 0a0f8965817e91bc158239f832c1da17 932 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 900 912 8.7E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28900 0a0f8965817e91bc158239f832c1da17 932 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 870 884 8.7E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28900 0a0f8965817e91bc158239f832c1da17 932 SUPERFAMILY SSF52540 133 252 9.32E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28900 0a0f8965817e91bc158239f832c1da17 932 SUPERFAMILY SSF52540 28 106 9.32E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18330 b4d01488260d5c137aeac8809e22013e 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 119 9.0E-11 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS18330 b4d01488260d5c137aeac8809e22013e 126 Gene3D G3DSA:3.10.180.10 7 123 3.8E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS18330 b4d01488260d5c137aeac8809e22013e 126 SUPERFAMILY SSF54593 1 124 1.02E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS04335 4b91e53d0050dd59a575c18aae4a85b5 505 SUPERFAMILY SSF47413 100 160 6.48E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS04335 4b91e53d0050dd59a575c18aae4a85b5 505 Gene3D G3DSA:1.10.260.40 104 160 3.1E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS04335 4b91e53d0050dd59a575c18aae4a85b5 505 SMART SM00530 108 164 8.0E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS04335 4b91e53d0050dd59a575c18aae4a85b5 505 Pfam PF13560 Helix-turn-helix domain 105 160 5.8E-14 T 06-07-2017 SMD11_RS15520 d401d81fc996927d857819099d138c99 154 SUPERFAMILY SSF55298 3 152 1.4E-55 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD11_RS15520 d401d81fc996927d857819099d138c99 154 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 5 152 6.9E-33 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD11_RS15520 d401d81fc996927d857819099d138c99 154 Gene3D G3DSA:3.30.1330.40 3 152 5.1E-67 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD11_RS26985 1589e9136229ed5518a82b8fc2c7a80d 421 Gene3D G3DSA:3.40.50.150 261 399 3.6E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS26985 1589e9136229ed5518a82b8fc2c7a80d 421 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 182 3.7E-20 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS26985 1589e9136229ed5518a82b8fc2c7a80d 421 Gene3D G3DSA:3.40.1010.10 5 103 1.0E-14 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS26985 1589e9136229ed5518a82b8fc2c7a80d 421 SUPERFAMILY SSF53790 8 197 1.96E-32 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS26985 1589e9136229ed5518a82b8fc2c7a80d 421 Gene3D G3DSA:3.30.950.10 104 197 1.5E-18 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SMD11_RS26985 1589e9136229ed5518a82b8fc2c7a80d 421 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 9 196 7.5E-37 T 06-07-2017 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 SMD11_RS26985 1589e9136229ed5518a82b8fc2c7a80d 421 SUPERFAMILY SSF53335 260 389 6.16E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29800 dd963cd36efdc97b183c775d515e4e97 422 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 252 9.8E-56 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS29800 dd963cd36efdc97b183c775d515e4e97 422 SUPERFAMILY SSF53901 3 105 2.4E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29800 dd963cd36efdc97b183c775d515e4e97 422 SUPERFAMILY SSF53901 142 415 2.4E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29800 dd963cd36efdc97b183c775d515e4e97 422 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 160 176 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS29800 dd963cd36efdc97b183c775d515e4e97 422 SMART SM00825 Beta-ketoacyl synthase 5 419 2.8E-15 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS29800 dd963cd36efdc97b183c775d515e4e97 422 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 260 374 2.3E-34 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS29800 dd963cd36efdc97b183c775d515e4e97 422 Gene3D G3DSA:3.40.47.10 3 263 4.3E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29800 dd963cd36efdc97b183c775d515e4e97 422 Gene3D G3DSA:3.40.47.10 270 417 3.8E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS24555 941920cf5dc52d1a9a77c53abb3b5914 407 Pfam PF05103 DivIVA protein 3 65 4.8E-14 T 06-07-2017 IPR007793 DivIVA family SMD11_RS24555 941920cf5dc52d1a9a77c53abb3b5914 407 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 38 1.4E-16 T 06-07-2017 IPR019933 DivIVA domain SMD11_RS29305 52c4f60a5382334ae1b5403ec7691c5e 366 Gene3D G3DSA:3.30.300.50 107 171 6.4E-9 T 06-07-2017 SMD11_RS29305 52c4f60a5382334ae1b5403ec7691c5e 366 Gene3D G3DSA:2.40.10.10 266 353 1.4E-28 T 06-07-2017 SMD11_RS29305 52c4f60a5382334ae1b5403ec7691c5e 366 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 316 327 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site SMD11_RS29305 52c4f60a5382334ae1b5403ec7691c5e 366 Pfam PF02983 Alpha-lytic protease prodomain 108 162 1.0E-15 T 06-07-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMD11_RS29305 52c4f60a5382334ae1b5403ec7691c5e 366 PIRSF PIRSF001134 6 366 1.1E-122 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS29305 52c4f60a5382334ae1b5403ec7691c5e 366 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 206 220 2.8E-44 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS29305 52c4f60a5382334ae1b5403ec7691c5e 366 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 307 330 2.8E-44 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS29305 52c4f60a5382334ae1b5403ec7691c5e 366 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 288 305 2.8E-44 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS29305 52c4f60a5382334ae1b5403ec7691c5e 366 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 267 287 2.8E-44 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS29305 52c4f60a5382334ae1b5403ec7691c5e 366 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 331 345 2.8E-44 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS29305 52c4f60a5382334ae1b5403ec7691c5e 366 Pfam PF00089 Trypsin 206 357 6.3E-11 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD11_RS29305 52c4f60a5382334ae1b5403ec7691c5e 366 SUPERFAMILY SSF50494 186 359 2.48E-39 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS29305 52c4f60a5382334ae1b5403ec7691c5e 366 Gene3D G3DSA:2.40.10.10 180 265 2.0E-31 T 06-07-2017 SMD11_RS29305 52c4f60a5382334ae1b5403ec7691c5e 366 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 208 213 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD11_RS29305 52c4f60a5382334ae1b5403ec7691c5e 366 Gene3D G3DSA:3.30.300.50 55 106 2.5E-6 T 06-07-2017 SMD11_RS09160 59eb7d04294266dd7be6846b6b8667d2 75 Pfam PF04149 Domain of unknown function (DUF397) 28 68 2.1E-8 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS15765 2308c55d64a4389b4a33df193b5b6430 411 SUPERFAMILY SSF103473 4 397 2.35E-41 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS15765 2308c55d64a4389b4a33df193b5b6430 411 Gene3D G3DSA:1.20.1250.20 5 170 1.6E-24 T 06-07-2017 SMD11_RS15765 2308c55d64a4389b4a33df193b5b6430 411 Gene3D G3DSA:1.20.1250.20 196 397 1.5E-7 T 06-07-2017 SMD11_RS15765 2308c55d64a4389b4a33df193b5b6430 411 Pfam PF07690 Major Facilitator Superfamily 3 356 2.7E-27 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS33000 c63c93afe5a9023431da1d0d35a06759 300 Gene3D G3DSA:3.40.50.620 241 249 3.9E-50 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS33000 c63c93afe5a9023431da1d0d35a06759 300 Gene3D G3DSA:3.40.50.620 5 208 3.9E-50 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS33000 c63c93afe5a9023431da1d0d35a06759 300 PIRSF PIRSF002936 1 300 3.5E-136 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMD11_RS33000 c63c93afe5a9023431da1d0d35a06759 300 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 9 300 4.6E-137 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 SMD11_RS33000 c63c93afe5a9023431da1d0d35a06759 300 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 30 254 3.9E-45 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 SMD11_RS33000 c63c93afe5a9023431da1d0d35a06759 300 SUPERFAMILY SSF52402 5 207 3.03E-61 T 06-07-2017 SMD11_RS26050 3dc8a0d8f8e55d84f5f3c176d527ae68 339 Gene3D G3DSA:3.30.1490.100 194 296 9.6E-13 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMD11_RS26050 3dc8a0d8f8e55d84f5f3c176d527ae68 339 Gene3D G3DSA:1.10.150.20 116 189 3.3E-17 T 06-07-2017 SMD11_RS26050 3dc8a0d8f8e55d84f5f3c176d527ae68 339 SUPERFAMILY SSF56672 23 186 1.11E-27 T 06-07-2017 SMD11_RS26050 3dc8a0d8f8e55d84f5f3c176d527ae68 339 Pfam PF11799 impB/mucB/samB family C-terminal domain 191 293 5.4E-10 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMD11_RS26050 3dc8a0d8f8e55d84f5f3c176d527ae68 339 SUPERFAMILY SSF100879 192 288 3.92E-13 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SMD11_RS26050 3dc8a0d8f8e55d84f5f3c176d527ae68 339 Gene3D G3DSA:3.30.70.270 34 103 2.8E-6 T 06-07-2017 SMD11_RS21900 3023817ff7918a44f8c8afc70ccac40f 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 57 3.8E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS21900 3023817ff7918a44f8c8afc70ccac40f 200 SUPERFAMILY SSF48498 83 198 1.75E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS21900 3023817ff7918a44f8c8afc70ccac40f 200 Gene3D G3DSA:1.10.357.10 2 199 4.5E-47 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS21900 3023817ff7918a44f8c8afc70ccac40f 200 SUPERFAMILY SSF46689 2 74 2.62E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS21900 3023817ff7918a44f8c8afc70ccac40f 200 Pfam PF13977 Bacterial transcriptional repressor 85 197 1.9E-18 T 06-07-2017 SMD11_RS07150 bec0c11b06f5356133bc56ce07d27f25 134 Gene3D G3DSA:1.10.10.10 76 131 6.8E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07150 bec0c11b06f5356133bc56ce07d27f25 134 SMART SM00421 68 125 5.8E-5 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07150 bec0c11b06f5356133bc56ce07d27f25 134 SUPERFAMILY SSF46894 75 131 5.44E-10 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS18350 c652c28c8f5a04458d39ae9bd1711433 238 Gene3D G3DSA:1.10.10.10 172 218 3.5E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS18350 c652c28c8f5a04458d39ae9bd1711433 238 Gene3D G3DSA:3.30.450.40 24 132 5.8E-8 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS18350 c652c28c8f5a04458d39ae9bd1711433 238 Pfam PF03861 ANTAR domain 171 216 8.0E-7 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 SMD11_RS18350 c652c28c8f5a04458d39ae9bd1711433 238 SMART SM01012 143 216 2.6E-4 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 SMD11_RS18350 c652c28c8f5a04458d39ae9bd1711433 238 SUPERFAMILY SSF55781 24 146 3.08E-11 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS22865 4dc1c0691053e6c1982b5252280db9d7 277 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 261 2.0E-74 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD11_RS22865 4dc1c0691053e6c1982b5252280db9d7 277 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 261 1.2E-78 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD11_RS22865 4dc1c0691053e6c1982b5252280db9d7 277 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 262 39.146 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD11_RS22865 4dc1c0691053e6c1982b5252280db9d7 277 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 207 224 - T 06-07-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 SMD11_RS22865 4dc1c0691053e6c1982b5252280db9d7 277 Gene3D G3DSA:3.40.1180.10 32 263 2.6E-93 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD11_RS22865 4dc1c0691053e6c1982b5252280db9d7 277 SUPERFAMILY SSF64005 34 257 6.54E-85 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD11_RS11750 f185f2b11040bc0a4d21891a371dd8e3 201 Pfam PF01914 MarC family integral membrane protein 6 197 2.1E-47 T 06-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 SMD11_RS11750 f185f2b11040bc0a4d21891a371dd8e3 201 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 6 194 4.2E-43 T 06-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 SMD11_RS18660 b65649761b6a3d4c18670caf37421989 349 SUPERFAMILY SSF52518 25 348 5.9E-85 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS18660 b65649761b6a3d4c18670caf37421989 349 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 61 208 5.5E-30 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SMD11_RS18660 b65649761b6a3d4c18670caf37421989 349 Gene3D G3DSA:3.40.50.970 15 251 1.2E-85 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS01310 f7ddb38b9465b3ef09b7ac33b6c83770 98 SUPERFAMILY SSF47336 6 87 9.68E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01310 f7ddb38b9465b3ef09b7ac33b6c83770 98 Pfam PF00550 Phosphopantetheine attachment site 11 75 2.1E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01310 f7ddb38b9465b3ef09b7ac33b6c83770 98 Gene3D G3DSA:1.10.1200.10 9 80 7.2E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS31785 d3efd70e1f2f1600ea44cd917c6c523f 260 Gene3D G3DSA:3.10.180.10 11 124 6.7E-31 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS31785 d3efd70e1f2f1600ea44cd917c6c523f 260 Gene3D G3DSA:3.10.180.10 138 256 2.8E-32 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS31785 d3efd70e1f2f1600ea44cd917c6c523f 260 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 142 250 1.3E-4 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS31785 d3efd70e1f2f1600ea44cd917c6c523f 260 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 119 5.4E-5 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS31785 d3efd70e1f2f1600ea44cd917c6c523f 260 SUPERFAMILY SSF54593 11 181 3.37E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS33970 9fa1f4c6a4313b1b88cf71f32ac27794 214 SUPERFAMILY SSF55781 5 97 1.73E-8 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS33970 9fa1f4c6a4313b1b88cf71f32ac27794 214 Gene3D G3DSA:3.30.450.40 4 85 3.3E-5 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS19375 dda3c9e1c6799efad9a2cfff61a34d8f 294 Gene3D G3DSA:3.90.226.10 31 233 6.4E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS19375 dda3c9e1c6799efad9a2cfff61a34d8f 294 Gene3D G3DSA:1.10.12.10 236 294 1.5E-19 T 06-07-2017 IPR014748 Crontonase, C-terminal SMD11_RS19375 dda3c9e1c6799efad9a2cfff61a34d8f 294 Pfam PF00378 Enoyl-CoA hydratase/isomerase 36 293 2.2E-61 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS19375 dda3c9e1c6799efad9a2cfff61a34d8f 294 SUPERFAMILY SSF52096 28 294 1.66E-84 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS06815 778face77e4e1ecef494961128f43aa0 348 SUPERFAMILY SSF50370 5 148 7.61E-17 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS06815 778face77e4e1ecef494961128f43aa0 348 Gene3D G3DSA:2.80.10.50 84 164 7.8E-6 T 06-07-2017 SMD11_RS06815 778face77e4e1ecef494961128f43aa0 348 Gene3D G3DSA:2.80.10.50 6 62 1.4E-7 T 06-07-2017 SMD11_RS06815 778face77e4e1ecef494961128f43aa0 348 Pfam PF04450 Peptidase of plants and bacteria 215 344 1.2E-18 T 06-07-2017 IPR007541 Uncharacterised protein family, basic secretory protein SMD11_RS20610 2fceaab16776e64a4a09355fe62fb747 267 Gene3D G3DSA:3.10.180.10 12 133 1.1E-35 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS20610 2fceaab16776e64a4a09355fe62fb747 267 Gene3D G3DSA:3.10.180.10 147 261 2.6E-28 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS20610 2fceaab16776e64a4a09355fe62fb747 267 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 127 9.5E-7 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS20610 2fceaab16776e64a4a09355fe62fb747 267 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 152 255 1.4E-7 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS20610 2fceaab16776e64a4a09355fe62fb747 267 SUPERFAMILY SSF54593 147 259 1.48E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS20610 2fceaab16776e64a4a09355fe62fb747 267 SUPERFAMILY SSF54593 10 184 9.8E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS23080 01998f1fa5864ef684ae84888aa1bd2b 189 Gene3D G3DSA:2.40.260.10 47 187 1.4E-9 T 06-07-2017 IPR023365 Sortase domain SMD11_RS23080 01998f1fa5864ef684ae84888aa1bd2b 189 Pfam PF04203 Sortase family 48 187 7.0E-17 T 06-07-2017 IPR005754 Sortase family SMD11_RS23080 01998f1fa5864ef684ae84888aa1bd2b 189 SUPERFAMILY SSF63817 43 187 5.89E-17 T 06-07-2017 IPR023365 Sortase domain SMD11_RS11580 6d0c895cc265f21c1d0928440c05e86e 760 Gene3D G3DSA:3.40.50.300 50 319 4.3E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11580 6d0c895cc265f21c1d0928440c05e86e 760 Gene3D G3DSA:1.10.150.80 681 744 4.4E-11 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 SMD11_RS11580 6d0c895cc265f21c1d0928440c05e86e 760 Pfam PF13361 UvrD-like helicase C-terminal domain 321 442 2.7E-13 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMD11_RS11580 6d0c895cc265f21c1d0928440c05e86e 760 Pfam PF13361 UvrD-like helicase C-terminal domain 487 594 7.6E-24 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SMD11_RS11580 6d0c895cc265f21c1d0928440c05e86e 760 SUPERFAMILY SSF47819 671 750 3.92E-19 T 06-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 SMD11_RS11580 6d0c895cc265f21c1d0928440c05e86e 760 Pfam PF00570 HRDC domain 682 747 3.3E-18 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 SMD11_RS11580 6d0c895cc265f21c1d0928440c05e86e 760 Gene3D G3DSA:3.40.50.300 531 614 2.1E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11580 6d0c895cc265f21c1d0928440c05e86e 760 Gene3D G3DSA:3.40.50.300 325 438 2.1E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11580 6d0c895cc265f21c1d0928440c05e86e 760 SUPERFAMILY SSF52540 44 614 1.56E-121 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11580 6d0c895cc265f21c1d0928440c05e86e 760 Pfam PF00580 UvrD/REP helicase N-terminal domain 52 127 4.3E-20 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 SMD11_RS11580 6d0c895cc265f21c1d0928440c05e86e 760 Pfam PF00580 UvrD/REP helicase N-terminal domain 199 313 1.1E-25 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 SMD11_RS11580 6d0c895cc265f21c1d0928440c05e86e 760 SMART SM00341 678 758 1.1E-12 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 SMD11_RS32145 2c68014bc227b67d9a335689ab35432f 332 Pfam PF03747 ADP-ribosylglycohydrolase 5 311 1.9E-56 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 SMD11_RS32145 2c68014bc227b67d9a335689ab35432f 332 SUPERFAMILY SSF101478 2 219 4.18E-57 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 SMD11_RS32145 2c68014bc227b67d9a335689ab35432f 332 SUPERFAMILY SSF101478 252 326 4.18E-57 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 SMD11_RS33850 0eb2b0f3bdead535c27c4ae5d8ed3cd0 505 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 270 445 2.0E-12 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SMD11_RS33850 0eb2b0f3bdead535c27c4ae5d8ed3cd0 505 Gene3D G3DSA:3.30.420.40 21 259 1.3E-48 T 06-07-2017 SMD11_RS33850 0eb2b0f3bdead535c27c4ae5d8ed3cd0 505 Gene3D G3DSA:3.30.420.40 261 481 3.4E-19 T 06-07-2017 SMD11_RS33850 0eb2b0f3bdead535c27c4ae5d8ed3cd0 505 PIRSF PIRSF000538 18 493 1.2E-66 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SMD11_RS33850 0eb2b0f3bdead535c27c4ae5d8ed3cd0 505 SUPERFAMILY SSF53067 21 261 6.31E-48 T 06-07-2017 SMD11_RS33850 0eb2b0f3bdead535c27c4ae5d8ed3cd0 505 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 21 258 5.1E-38 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SMD11_RS33850 0eb2b0f3bdead535c27c4ae5d8ed3cd0 505 SUPERFAMILY SSF53067 263 478 2.36E-23 T 06-07-2017 SMD11_RS15995 47d729191df4a73a5c1906de5e987134 210 Pfam PF03358 NADPH-dependent FMN reductase 3 152 1.1E-16 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMD11_RS15995 47d729191df4a73a5c1906de5e987134 210 Gene3D G3DSA:3.40.50.360 1 205 1.5E-53 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS15995 47d729191df4a73a5c1906de5e987134 210 SUPERFAMILY SSF52218 1 202 2.88E-42 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS07330 72ae1b0fd5fcb9af4dcb7c7d965cf657 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 378 470 5.2E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS07330 72ae1b0fd5fcb9af4dcb7c7d965cf657 487 SMART SM00387 376 472 4.6E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS07330 72ae1b0fd5fcb9af4dcb7c7d965cf657 487 Pfam PF07730 Histidine kinase 278 342 4.1E-16 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS07330 72ae1b0fd5fcb9af4dcb7c7d965cf657 487 Gene3D G3DSA:3.30.565.10 374 472 1.8E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS07330 72ae1b0fd5fcb9af4dcb7c7d965cf657 487 SUPERFAMILY SSF55874 351 469 2.87E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS07700 2d8dd078f4412464cb0dc2fab1480603 215 SMART SM00267 21 187 2.4E-35 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS07700 2d8dd078f4412464cb0dc2fab1480603 215 Gene3D G3DSA:3.30.70.270 34 183 3.8E-35 T 06-07-2017 SMD11_RS07700 2d8dd078f4412464cb0dc2fab1480603 215 Pfam PF00990 Diguanylate cyclase, GGDEF domain 32 180 3.2E-28 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS07700 2d8dd078f4412464cb0dc2fab1480603 215 SUPERFAMILY SSF55073 37 188 2.88E-31 T 06-07-2017 IPR029787 Nucleotide cyclase SMD11_RS07700 2d8dd078f4412464cb0dc2fab1480603 215 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 30 180 7.9E-22 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS11945 c59e8feb92b22bfc783d6a51b6675f6c 297 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 13 295 6.6E-124 T 06-07-2017 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD11_RS11945 c59e8feb92b22bfc783d6a51b6675f6c 297 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 12 295 42.131 T 06-07-2017 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 SMD11_RS11945 c59e8feb92b22bfc783d6a51b6675f6c 297 Pfam PF02585 GlcNAc-PI de-N-acetylase 13 163 3.2E-26 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 SMD11_RS11945 c59e8feb92b22bfc783d6a51b6675f6c 297 SUPERFAMILY SSF102588 9 295 1.07E-68 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD11_RS11945 c59e8feb92b22bfc783d6a51b6675f6c 297 Gene3D G3DSA:3.40.50.10320 8 295 4.7E-94 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 SMD11_RS00975 9c0e73e7596964f27063e3b6b38c36d5 506 SUPERFAMILY SSF51261 22 156 3.3E-38 T 06-07-2017 IPR011055 Duplicated hybrid motif SMD11_RS00975 9c0e73e7596964f27063e3b6b38c36d5 506 Pfam PF01551 Peptidase family M23 54 142 8.4E-28 T 06-07-2017 IPR016047 Peptidase M23 SMD11_RS00975 9c0e73e7596964f27063e3b6b38c36d5 506 Gene3D G3DSA:2.70.70.10 45 157 4.9E-36 T 06-07-2017 SMD11_RS00975 9c0e73e7596964f27063e3b6b38c36d5 506 SUPERFAMILY SSF89372 192 365 7.85E-22 T 06-07-2017 SMD11_RS08785 ea73b10e57920af2f81e02ac563c8cd2 276 Pfam PF00797 N-acetyltransferase 29 262 3.6E-65 T 06-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD11_RS08785 ea73b10e57920af2f81e02ac563c8cd2 276 SUPERFAMILY SSF54001 10 268 5.64E-74 T 06-07-2017 SMD11_RS08785 ea73b10e57920af2f81e02ac563c8cd2 276 Gene3D G3DSA:3.30.2140.10 190 266 1.2E-49 T 06-07-2017 SMD11_RS08785 ea73b10e57920af2f81e02ac563c8cd2 276 Gene3D G3DSA:3.30.2140.10 11 93 1.2E-49 T 06-07-2017 SMD11_RS08785 ea73b10e57920af2f81e02ac563c8cd2 276 PRINTS PR01543 Arylamine N-acetyltransferase signature 77 99 3.7E-10 T 06-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD11_RS08785 ea73b10e57920af2f81e02ac563c8cd2 276 PRINTS PR01543 Arylamine N-acetyltransferase signature 53 76 3.7E-10 T 06-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD11_RS08785 ea73b10e57920af2f81e02ac563c8cd2 276 PRINTS PR01543 Arylamine N-acetyltransferase signature 29 52 3.7E-10 T 06-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD11_RS16015 2e2936fe219103e17b6c7d7b2124feeb 96 Gene3D G3DSA:2.10.230.10 59 94 2.6E-5 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMD11_RS16015 2e2936fe219103e17b6c7d7b2124feeb 96 SUPERFAMILY SSF57938 58 94 3.14E-5 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SMD11_RS02255 7753ceaffdf009f38f33ad0cf015b7d4 483 SUPERFAMILY SSF56796 131 414 3.14E-23 T 06-07-2017 SMD11_RS02255 7753ceaffdf009f38f33ad0cf015b7d4 483 Pfam PF01761 3-dehydroquinate synthase 257 416 2.3E-16 T 06-07-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 SMD11_RS02255 7753ceaffdf009f38f33ad0cf015b7d4 483 Gene3D G3DSA:3.40.50.1970 131 239 4.5E-4 T 06-07-2017 SMD11_RS02255 7753ceaffdf009f38f33ad0cf015b7d4 483 Gene3D G3DSA:1.20.1090.10 272 437 5.3E-14 T 06-07-2017 SMD11_RS00245 b6269a0ab9bd8b9ee3def9cda29b0f9a 378 SUPERFAMILY SSF55909 36 372 1.53E-108 T 06-07-2017 SMD11_RS00245 b6269a0ab9bd8b9ee3def9cda29b0f9a 378 Gene3D G3DSA:3.75.10.10 38 373 2.9E-119 T 06-07-2017 SMD11_RS00245 b6269a0ab9bd8b9ee3def9cda29b0f9a 378 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 43 372 4.2E-108 T 06-07-2017 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 SMD11_RS24400 62ec196f12267e44ec9d6b9ffa29f8bf 392 Gene3D G3DSA:3.30.9.10 218 325 5.4E-16 T 06-07-2017 SMD11_RS24400 62ec196f12267e44ec9d6b9ffa29f8bf 392 Gene3D G3DSA:3.30.9.10 89 155 1.0E-4 T 06-07-2017 SMD11_RS24400 62ec196f12267e44ec9d6b9ffa29f8bf 392 SUPERFAMILY SSF54373 233 325 1.57E-21 T 06-07-2017 SMD11_RS24400 62ec196f12267e44ec9d6b9ffa29f8bf 392 Gene3D G3DSA:3.50.50.60 156 217 2.7E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24400 62ec196f12267e44ec9d6b9ffa29f8bf 392 Gene3D G3DSA:3.50.50.60 7 88 2.7E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24400 62ec196f12267e44ec9d6b9ffa29f8bf 392 Gene3D G3DSA:3.50.50.60 327 384 2.7E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24400 62ec196f12267e44ec9d6b9ffa29f8bf 392 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 14 368 2.0E-116 T 06-07-2017 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 SMD11_RS24400 62ec196f12267e44ec9d6b9ffa29f8bf 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 187 212 2.5E-5 T 06-07-2017 SMD11_RS24400 62ec196f12267e44ec9d6b9ffa29f8bf 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 2.5E-5 T 06-07-2017 SMD11_RS24400 62ec196f12267e44ec9d6b9ffa29f8bf 392 SUPERFAMILY SSF51905 327 384 1.1E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24400 62ec196f12267e44ec9d6b9ffa29f8bf 392 SUPERFAMILY SSF51905 11 232 1.1E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24400 62ec196f12267e44ec9d6b9ffa29f8bf 392 Pfam PF01266 FAD dependent oxidoreductase 13 364 3.4E-61 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD11_RS29365 d755370e0590e10e9772e1efdac8768a 90 SUPERFAMILY SSF47336 13 89 6.15E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29365 d755370e0590e10e9772e1efdac8768a 90 Pfam PF00550 Phosphopantetheine attachment site 13 79 2.8E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29365 d755370e0590e10e9772e1efdac8768a 90 Gene3D G3DSA:1.10.1200.10 13 85 3.9E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29365 d755370e0590e10e9772e1efdac8768a 90 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 80 0.006 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS31440 ef0d62bd91edee14b9aab7f16cf1b088 851 SUPERFAMILY SSF52540 593 827 6.56E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31440 ef0d62bd91edee14b9aab7f16cf1b088 851 SUPERFAMILY SSF52540 321 570 1.97E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31440 ef0d62bd91edee14b9aab7f16cf1b088 851 Gene3D G3DSA:3.40.50.300 592 777 1.8E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31440 ef0d62bd91edee14b9aab7f16cf1b088 851 SMART SM00382 356 495 3.1E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS31440 ef0d62bd91edee14b9aab7f16cf1b088 851 SMART SM00382 625 760 5.1E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS31440 ef0d62bd91edee14b9aab7f16cf1b088 851 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 361 474 2.3E-13 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS31440 ef0d62bd91edee14b9aab7f16cf1b088 851 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 629 761 2.2E-14 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS31440 ef0d62bd91edee14b9aab7f16cf1b088 851 PRINTS PR00819 CbxX/CfqX superfamily signature 539 551 1.9E-37 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS31440 ef0d62bd91edee14b9aab7f16cf1b088 851 PRINTS PR00819 CbxX/CfqX superfamily signature 317 331 1.9E-37 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS31440 ef0d62bd91edee14b9aab7f16cf1b088 851 PRINTS PR00819 CbxX/CfqX superfamily signature 397 411 1.9E-37 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS31440 ef0d62bd91edee14b9aab7f16cf1b088 851 PRINTS PR00819 CbxX/CfqX superfamily signature 359 374 1.9E-37 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS31440 ef0d62bd91edee14b9aab7f16cf1b088 851 PRINTS PR00819 CbxX/CfqX superfamily signature 411 430 1.9E-37 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS31440 ef0d62bd91edee14b9aab7f16cf1b088 851 PRINTS PR00819 CbxX/CfqX superfamily signature 461 478 1.9E-37 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS31440 ef0d62bd91edee14b9aab7f16cf1b088 851 PRINTS PR00819 CbxX/CfqX superfamily signature 440 452 1.9E-37 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 SMD11_RS31440 ef0d62bd91edee14b9aab7f16cf1b088 851 Gene3D G3DSA:3.40.50.300 355 494 6.6E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31915 81d5664306f3fb407098fa545d8b172a 842 SUPERFAMILY SSF144091 34 223 4.19E-9 T 06-07-2017 SMD11_RS31915 81d5664306f3fb407098fa545d8b172a 842 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 509 807 2.8E-99 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal SMD11_RS31915 81d5664306f3fb407098fa545d8b172a 842 Gene3D G3DSA:1.20.1540.10 36 220 1.2E-4 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMD11_RS24795 87c7d50ce71db437bd123ef1ed5345c6 222 Pfam PF06439 Domain of Unknown Function (DUF1080) 154 217 4.6E-7 T 06-07-2017 IPR010496 Domain of unknown function DUF1080 SMD11_RS14280 b05a7ae18cff43ecd5f4bd55f6040d11 79 Pfam PF08962 Domain of unknown function (DUF1876) 5 78 5.3E-27 T 06-07-2017 IPR015057 Protein of unknown function DUF1876 SMD11_RS14280 b05a7ae18cff43ecd5f4bd55f6040d11 79 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 3 77 3.0E-16 T 06-07-2017 IPR015057 Protein of unknown function DUF1876 SMD11_RS14280 b05a7ae18cff43ecd5f4bd55f6040d11 79 SUPERFAMILY SSF143212 3 77 1.7E-23 T 06-07-2017 SMD11_RS26100 ecf8c81ca73cfcb8f7942acce75cfb81 616 Pfam PF00733 Asparagine synthase 241 608 5.9E-86 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMD11_RS26100 ecf8c81ca73cfcb8f7942acce75cfb81 616 Gene3D G3DSA:3.40.50.620 469 586 1.9E-74 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS26100 ecf8c81ca73cfcb8f7942acce75cfb81 616 Gene3D G3DSA:3.40.50.620 225 402 1.9E-74 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS26100 ecf8c81ca73cfcb8f7942acce75cfb81 616 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 545 3.3E-148 T 06-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 SMD11_RS26100 ecf8c81ca73cfcb8f7942acce75cfb81 616 Pfam PF13537 Glutamine amidotransferase domain 48 170 7.4E-46 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain SMD11_RS26100 ecf8c81ca73cfcb8f7942acce75cfb81 616 Gene3D G3DSA:3.60.20.10 1 224 1.5E-78 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS26100 ecf8c81ca73cfcb8f7942acce75cfb81 616 SUPERFAMILY SSF52402 465 585 1.19E-62 T 06-07-2017 SMD11_RS26100 ecf8c81ca73cfcb8f7942acce75cfb81 616 SUPERFAMILY SSF52402 230 398 1.19E-62 T 06-07-2017 SMD11_RS26100 ecf8c81ca73cfcb8f7942acce75cfb81 616 PIRSF PIRSF001589 1 615 8.3E-139 T 06-07-2017 SMD11_RS26100 ecf8c81ca73cfcb8f7942acce75cfb81 616 SUPERFAMILY SSF56235 1 225 9.44E-67 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS24910 1af50761f588cb548a96ece6f440098d 214 SUPERFAMILY SSF52172 19 204 4.55E-56 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS24910 1af50761f588cb548a96ece6f440098d 214 Gene3D G3DSA:3.40.50.2300 16 144 2.8E-38 T 06-07-2017 SMD11_RS24910 1af50761f588cb548a96ece6f440098d 214 SMART SM01012 149 204 6.3E-24 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 SMD11_RS24910 1af50761f588cb548a96ece6f440098d 214 Pfam PF03861 ANTAR domain 152 204 6.7E-21 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 SMD11_RS24910 1af50761f588cb548a96ece6f440098d 214 PIRSF PIRSF036382 14 211 5.7E-69 T 06-07-2017 IPR008327 Signal transduction response regulator, antiterminator SMD11_RS24910 1af50761f588cb548a96ece6f440098d 214 Gene3D G3DSA:1.10.10.10 151 207 1.3E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS24910 1af50761f588cb548a96ece6f440098d 214 SMART SM00448 22 133 4.4E-38 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS24910 1af50761f588cb548a96ece6f440098d 214 Pfam PF00072 Response regulator receiver domain 24 133 3.5E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS10915 c4f64288dbbff7a054b78bdf32bd3533 263 Gene3D G3DSA:3.20.20.370 65 257 4.1E-53 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS10915 c4f64288dbbff7a054b78bdf32bd3533 263 Pfam PF01522 Polysaccharide deacetylase 72 194 7.7E-26 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS10915 c4f64288dbbff7a054b78bdf32bd3533 263 SUPERFAMILY SSF88713 66 257 1.71E-51 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS01550 d0d6fd6ce4d4391d09061dd3cefebb19 311 SUPERFAMILY SSF56059 114 303 7.07E-43 T 06-07-2017 SMD11_RS01550 d0d6fd6ce4d4391d09061dd3cefebb19 311 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 2 111 5.3E-20 T 06-07-2017 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 SMD11_RS01550 d0d6fd6ce4d4391d09061dd3cefebb19 311 Hamap MF_00162 Glutathione synthetase [gshB]. 1 307 95.17 T 06-07-2017 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 SMD11_RS01550 d0d6fd6ce4d4391d09061dd3cefebb19 311 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 115 287 2.0E-53 T 06-07-2017 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 SMD11_RS01550 d0d6fd6ce4d4391d09061dd3cefebb19 311 Gene3D G3DSA:3.40.50.20 3 119 3.7E-25 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS01550 d0d6fd6ce4d4391d09061dd3cefebb19 311 Gene3D G3DSA:3.30.470.20 184 289 3.1E-36 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS01550 d0d6fd6ce4d4391d09061dd3cefebb19 311 Gene3D G3DSA:3.30.1490.20 128 183 6.2E-14 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS01550 d0d6fd6ce4d4391d09061dd3cefebb19 311 SUPERFAMILY SSF52440 3 112 4.03E-18 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS24245 3c505aee2b3bf4b3aa5bba2e0e6cab7d 93 Gene3D G3DSA:3.30.70.920 4 78 1.5E-25 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS24245 3c505aee2b3bf4b3aa5bba2e0e6cab7d 93 SUPERFAMILY SSF54909 3 78 9.12E-19 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS24245 3c505aee2b3bf4b3aa5bba2e0e6cab7d 93 Pfam PF01037 Lrp/AsnC ligand binding domain 6 77 3.3E-17 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS28510 f6111d657ca6d61376229e448f4eebde 73 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 43 55 3.2E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28510 f6111d657ca6d61376229e448f4eebde 73 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 27 43 3.2E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28510 f6111d657ca6d61376229e448f4eebde 73 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 13 27 3.2E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28510 f6111d657ca6d61376229e448f4eebde 73 ProSitePatterns PS00622 LuxR-type HTH domain signature. 27 54 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28510 f6111d657ca6d61376229e448f4eebde 73 Pfam PF00196 Bacterial regulatory proteins, luxR family 12 66 2.9E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS28510 f6111d657ca6d61376229e448f4eebde 73 SUPERFAMILY SSF46894 6 68 2.62E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS28510 f6111d657ca6d61376229e448f4eebde 73 Gene3D G3DSA:1.10.10.10 12 68 6.2E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28510 f6111d657ca6d61376229e448f4eebde 73 SMART SM00421 10 67 6.6E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS09450 64db02238848fa89f0dee8896fb7107c 165 SMART SM00344 20 124 7.1E-36 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD11_RS09450 64db02238848fa89f0dee8896fb7107c 165 ProSitePatterns PS00519 AsnC-type HTH domain signature. 38 64 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMD11_RS09450 64db02238848fa89f0dee8896fb7107c 165 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 47 3.5E-11 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS09450 64db02238848fa89f0dee8896fb7107c 165 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 36 3.5E-11 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS09450 64db02238848fa89f0dee8896fb7107c 165 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 47 66 3.5E-11 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS09450 64db02238848fa89f0dee8896fb7107c 165 SUPERFAMILY SSF46785 20 74 6.49E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS09450 64db02238848fa89f0dee8896fb7107c 165 SUPERFAMILY SSF54909 82 161 6.44E-16 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS09450 64db02238848fa89f0dee8896fb7107c 165 Gene3D G3DSA:3.30.70.920 83 154 1.9E-17 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS09450 64db02238848fa89f0dee8896fb7107c 165 Gene3D G3DSA:1.10.10.10 19 67 1.5E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS09450 64db02238848fa89f0dee8896fb7107c 165 Pfam PF13404 AsnC-type helix-turn-helix domain 20 60 4.9E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS09450 64db02238848fa89f0dee8896fb7107c 165 Pfam PF01037 Lrp/AsnC ligand binding domain 85 154 1.9E-16 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 Gene3D G3DSA:1.10.10.10 60 149 3.8E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 SMART SM00862 66 146 9.9E-10 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 Pfam PF00486 Transcriptional regulatory protein, C terminal 73 145 4.5E-5 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 SUPERFAMILY SSF48452 758 876 7.59E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 PRINTS PR00364 Disease resistance protein signature 512 526 7.5E-9 T 06-07-2017 SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 PRINTS PR00364 Disease resistance protein signature 427 441 7.5E-9 T 06-07-2017 SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 PRINTS PR00364 Disease resistance protein signature 350 365 7.5E-9 T 06-07-2017 SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 Gene3D G3DSA:1.25.40.10 859 1002 3.1E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 Pfam PF00931 NB-ARC domain 346 530 1.7E-8 T 06-07-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 SUPERFAMILY SSF52540 316 578 4.82E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 Gene3D G3DSA:3.40.50.300 348 440 3.4E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 SUPERFAMILY SSF46894 53 145 2.35E-10 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 Pfam PF03704 Bacterial transcriptional activator domain 153 292 3.8E-31 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 Gene3D G3DSA:1.25.40.10 746 858 2.0E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 SUPERFAMILY SSF48452 880 993 1.03E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 SUPERFAMILY SSF48452 148 316 7.59E-22 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS06825 4eed04d5abab14a0eb7af6baf6f42750 1025 SMART SM01043 153 297 3.6E-28 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS07815 fdba9ab1401d4f4d1e2cd91d65ea785d 404 Pfam PF01494 FAD binding domain 9 339 1.0E-24 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS07815 fdba9ab1401d4f4d1e2cd91d65ea785d 404 SUPERFAMILY SSF51905 8 172 1.17E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07815 fdba9ab1401d4f4d1e2cd91d65ea785d 404 SUPERFAMILY SSF51905 268 372 1.17E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07815 fdba9ab1401d4f4d1e2cd91d65ea785d 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 3.8E-17 T 06-07-2017 SMD11_RS07815 fdba9ab1401d4f4d1e2cd91d65ea785d 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 330 346 3.8E-17 T 06-07-2017 SMD11_RS07815 fdba9ab1401d4f4d1e2cd91d65ea785d 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 3.8E-17 T 06-07-2017 SMD11_RS07815 fdba9ab1401d4f4d1e2cd91d65ea785d 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 3.8E-17 T 06-07-2017 SMD11_RS07815 fdba9ab1401d4f4d1e2cd91d65ea785d 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 3.8E-17 T 06-07-2017 SMD11_RS07815 fdba9ab1401d4f4d1e2cd91d65ea785d 404 Gene3D G3DSA:3.50.50.60 8 178 3.5E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07815 fdba9ab1401d4f4d1e2cd91d65ea785d 404 Gene3D G3DSA:3.50.50.60 268 351 3.5E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05155 27af1b2892b437c373fee0e11a6e5dc0 229 Gene3D G3DSA:1.10.260.40 30 94 2.4E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS05155 27af1b2892b437c373fee0e11a6e5dc0 229 SMART SM00530 26 81 7.9E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS05155 27af1b2892b437c373fee0e11a6e5dc0 229 Pfam PF13560 Helix-turn-helix domain 30 82 6.1E-11 T 06-07-2017 SMD11_RS05155 27af1b2892b437c373fee0e11a6e5dc0 229 Gene3D G3DSA:2.30.110.10 101 227 5.3E-36 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS05155 27af1b2892b437c373fee0e11a6e5dc0 229 SUPERFAMILY SSF50475 103 225 1.32E-20 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS05155 27af1b2892b437c373fee0e11a6e5dc0 229 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 106 224 1.2E-21 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related SMD11_RS05155 27af1b2892b437c373fee0e11a6e5dc0 229 SUPERFAMILY SSF47413 22 86 3.94E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS25215 7a6c3d2ddc218d8ea51d696504ff7d5e 392 SUPERFAMILY SSF101960 36 388 1.44E-91 T 06-07-2017 SMD11_RS25215 7a6c3d2ddc218d8ea51d696504ff7d5e 392 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 110 379 4.1E-74 T 06-07-2017 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 SMD11_RS25215 7a6c3d2ddc218d8ea51d696504ff7d5e 392 Pfam PF01458 Uncharacterized protein family (UPF0051) 142 362 3.6E-70 T 06-07-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 SMD11_RS26965 dd7fcf8e9c32e1fa1c6b48b14fa42af3 355 Gene3D G3DSA:3.30.70.260 257 336 2.9E-21 T 06-07-2017 SMD11_RS26965 dd7fcf8e9c32e1fa1c6b48b14fa42af3 355 Pfam PF00005 ABC transporter 26 180 3.4E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS26965 dd7fcf8e9c32e1fa1c6b48b14fa42af3 355 SMART SM00930 262 337 3.2E-19 T 06-07-2017 IPR018449 NIL domain SMD11_RS26965 dd7fcf8e9c32e1fa1c6b48b14fa42af3 355 SUPERFAMILY SSF52540 7 248 8.64E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26965 dd7fcf8e9c32e1fa1c6b48b14fa42af3 355 Pfam PF09383 NIL domain 264 336 4.6E-18 T 06-07-2017 IPR018449 NIL domain SMD11_RS26965 dd7fcf8e9c32e1fa1c6b48b14fa42af3 355 Gene3D G3DSA:3.40.50.300 5 250 2.4E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26965 dd7fcf8e9c32e1fa1c6b48b14fa42af3 355 SUPERFAMILY SSF55021 258 336 1.37E-16 T 06-07-2017 SMD11_RS26965 dd7fcf8e9c32e1fa1c6b48b14fa42af3 355 SMART SM00382 35 237 5.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS26965 dd7fcf8e9c32e1fa1c6b48b14fa42af3 355 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS33655 992bf6c3826489937c30ad1f7bdb0b2e 173 Gene3D G3DSA:2.60.60.20 3 92 2.2E-26 T 06-07-2017 IPR001024 PLAT/LH2 domain GO:0005515 SMD11_RS33655 992bf6c3826489937c30ad1f7bdb0b2e 173 SUPERFAMILY SSF49723 4 92 2.4E-25 T 06-07-2017 IPR001024 PLAT/LH2 domain GO:0005515 SMD11_RS33655 992bf6c3826489937c30ad1f7bdb0b2e 173 SMART SM00308 5 103 0.009 T 06-07-2017 IPR001024 PLAT/LH2 domain GO:0005515 SMD11_RS33655 992bf6c3826489937c30ad1f7bdb0b2e 173 Pfam PF01477 PLAT/LH2 domain 7 94 3.1E-15 T 06-07-2017 IPR001024 PLAT/LH2 domain GO:0005515 SMD11_RS12830 3ae1292a414a34ca8278482b5d89955b 532 Gene3D G3DSA:3.40.50.300 256 500 1.2E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12830 3ae1292a414a34ca8278482b5d89955b 532 Gene3D G3DSA:3.40.50.300 8 233 1.8E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12830 3ae1292a414a34ca8278482b5d89955b 532 SUPERFAMILY SSF52540 252 495 2.21E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12830 3ae1292a414a34ca8278482b5d89955b 532 Pfam PF00005 ABC transporter 280 436 6.9E-17 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS12830 3ae1292a414a34ca8278482b5d89955b 532 Pfam PF00005 ABC transporter 27 172 8.2E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS12830 3ae1292a414a34ca8278482b5d89955b 532 SMART SM00382 35 220 8.8E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS12830 3ae1292a414a34ca8278482b5d89955b 532 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS12830 3ae1292a414a34ca8278482b5d89955b 532 SUPERFAMILY SSF52540 9 229 4.18E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS29955 690f0f8aace7655b8bdee4b181b435e4 292 SUPERFAMILY SSF55048 122 188 3.92E-9 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS29955 690f0f8aace7655b8bdee4b181b435e4 292 Gene3D G3DSA:3.30.70.250 120 187 8.2E-10 T 06-07-2017 SMD11_RS29955 690f0f8aace7655b8bdee4b181b435e4 292 Pfam PF00698 Acyl transferase domain 6 262 4.2E-23 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS29955 690f0f8aace7655b8bdee4b181b435e4 292 PIRSF PIRSF000446 1 288 3.1E-66 T 06-07-2017 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 SMD11_RS29955 690f0f8aace7655b8bdee4b181b435e4 292 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 292 2.2E-28 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS29955 690f0f8aace7655b8bdee4b181b435e4 292 SUPERFAMILY SSF52151 181 284 3.92E-57 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS29955 690f0f8aace7655b8bdee4b181b435e4 292 SUPERFAMILY SSF52151 3 118 3.92E-57 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS29955 690f0f8aace7655b8bdee4b181b435e4 292 Gene3D G3DSA:3.40.366.10 188 280 3.6E-53 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS29955 690f0f8aace7655b8bdee4b181b435e4 292 Gene3D G3DSA:3.40.366.10 3 118 3.6E-53 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS23530 5c2e30b8553e30dcf22875a5f682aaee 218 Gene3D G3DSA:1.10.357.10 29 204 4.0E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS23530 5c2e30b8553e30dcf22875a5f682aaee 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 2.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS23530 5c2e30b8553e30dcf22875a5f682aaee 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 2.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS23530 5c2e30b8553e30dcf22875a5f682aaee 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 78 4.4E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS23530 5c2e30b8553e30dcf22875a5f682aaee 218 SUPERFAMILY SSF46689 22 94 4.09E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS30870 73378d0488ce8a2e8e70c1faf958c581 192 SUPERFAMILY SSF50370 32 149 3.34E-5 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS09800 44d2125c997b26b166f42041a61fa093 201 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 40.118 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 SMD11_RS09800 44d2125c997b26b166f42041a61fa093 201 SUPERFAMILY SSF52016 1 187 3.92E-53 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMD11_RS09800 44d2125c997b26b166f42041a61fa093 201 Gene3D G3DSA:3.20.19.10 1 187 3.9E-41 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel SMD11_RS09800 44d2125c997b26b166f42041a61fa093 201 Pfam PF00694 Aconitase C-terminal domain 1 117 5.0E-25 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 SMD11_RS09800 44d2125c997b26b166f42041a61fa093 201 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 179 2.8E-53 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 SMD11_RS16990 5052145693908a66ccf29d634210cfd3 290 SUPERFAMILY SSF144091 80 261 8.11E-45 T 06-07-2017 SMD11_RS16990 5052145693908a66ccf29d634210cfd3 290 Pfam PF01694 Rhomboid family 122 256 1.2E-37 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMD11_RS16990 5052145693908a66ccf29d634210cfd3 290 Gene3D G3DSA:1.20.1540.10 83 254 4.0E-42 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 SUPERFAMILY SSF53784 1 335 3.79E-119 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 323 8.2E-149 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 343 42.766 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 ProSitePatterns PS00433 Phosphofructokinase signature. 267 285 - T 06-07-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 7.6E-71 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 7.6E-71 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 7.6E-71 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 7.6E-71 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 7.6E-71 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 7.6E-71 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 263 285 7.6E-71 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 7.6E-71 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 7.6E-71 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 Gene3D G3DSA:3.40.50.450 1 210 2.1E-72 T 06-07-2017 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 Pfam PF00365 Phosphofructokinase 2 298 1.1E-102 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS24350 89be2cbd0e89c64bc3544c9a37286d4b 343 PIRSF PIRSF000532 1 341 2.0E-122 T 06-07-2017 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 06-07-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 42.622 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 Gene3D G3DSA:3.40.50.450 1 213 2.2E-71 T 06-07-2017 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 Pfam PF00365 Phosphofructokinase 2 297 1.6E-98 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 SUPERFAMILY SSF53784 1 332 3.53E-118 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 PIRSF PIRSF000532 1 340 2.0E-113 T 06-07-2017 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.0E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 1.0E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 1.0E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.0E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.0E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.0E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.0E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 1.0E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.0E-73 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SMD11_RS10555 c7f88d571bf14c2dd36f6e8e5abbe670 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 323 7.3E-142 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SMD11_RS02675 d2c940fa133452d60a8489f6ade7ba50 104 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 16 95 1.9E-26 T 06-07-2017 SMD11_RS02675 d2c940fa133452d60a8489f6ade7ba50 104 SUPERFAMILY SSF54292 18 97 1.97E-19 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS02675 d2c940fa133452d60a8489f6ade7ba50 104 Gene3D G3DSA:3.10.20.30 8 87 8.5E-6 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS05605 75432c547f720398edd47ace830322a8 356 Gene3D G3DSA:3.20.20.30 75 310 1.2E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS05605 75432c547f720398edd47ace830322a8 356 SUPERFAMILY SSF51679 65 331 1.04E-48 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS05605 75432c547f720398edd47ace830322a8 356 Pfam PF00296 Luciferase-like monooxygenase 75 337 4.4E-43 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS05605 75432c547f720398edd47ace830322a8 356 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 82 329 1.2E-61 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted SMD11_RS07295 6bd4362d12f576cf5bcbcd5c53834140 311 Gene3D G3DSA:3.40.190.10 82 179 5.1E-21 T 06-07-2017 SMD11_RS07295 6bd4362d12f576cf5bcbcd5c53834140 311 Pfam PF03466 LysR substrate binding domain 88 269 4.4E-28 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS07295 6bd4362d12f576cf5bcbcd5c53834140 311 Gene3D G3DSA:3.40.190.10 180 263 1.5E-11 T 06-07-2017 SMD11_RS07295 6bd4362d12f576cf5bcbcd5c53834140 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.6E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS07295 6bd4362d12f576cf5bcbcd5c53834140 311 Gene3D G3DSA:1.10.10.10 1 81 6.6E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07295 6bd4362d12f576cf5bcbcd5c53834140 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.7E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS07295 6bd4362d12f576cf5bcbcd5c53834140 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.7E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS07295 6bd4362d12f576cf5bcbcd5c53834140 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.7E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS07295 6bd4362d12f576cf5bcbcd5c53834140 311 SUPERFAMILY SSF53850 90 288 1.55E-28 T 06-07-2017 SMD11_RS07295 6bd4362d12f576cf5bcbcd5c53834140 311 SUPERFAMILY SSF46785 1 111 3.91E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS10465 8459d0ca33a8daa2fc16fc10bd938350 202 Gene3D G3DSA:1.10.357.10 1 184 7.9E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS10465 8459d0ca33a8daa2fc16fc10bd938350 202 SUPERFAMILY SSF46689 4 66 3.89E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS10465 8459d0ca33a8daa2fc16fc10bd938350 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 56 5.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS16235 894ccc31078db9497037f645437904c0 226 Gene3D G3DSA:3.30.70.900 11 101 4.4E-8 T 06-07-2017 SMD11_RS16235 894ccc31078db9497037f645437904c0 226 Gene3D G3DSA:3.30.70.900 126 216 9.4E-15 T 06-07-2017 SMD11_RS16235 894ccc31078db9497037f645437904c0 226 SUPERFAMILY SSF54909 125 201 1.56E-6 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS09475 059c9ecc63386b3a390899c254755d04 307 SUPERFAMILY SSF103481 57 133 9.42E-6 T 06-07-2017 SMD11_RS26270 c3e853f0b3bc5a5717c9e8b475342df9 146 Gene3D G3DSA:1.10.10.10 7 142 7.4E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26270 c3e853f0b3bc5a5717c9e8b475342df9 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 8.2E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS26270 c3e853f0b3bc5a5717c9e8b475342df9 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 8.2E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS26270 c3e853f0b3bc5a5717c9e8b475342df9 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 8.2E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS26270 c3e853f0b3bc5a5717c9e8b475342df9 146 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site SMD11_RS26270 c3e853f0b3bc5a5717c9e8b475342df9 146 SMART SM00347 31 128 2.5E-20 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS26270 c3e853f0b3bc5a5717c9e8b475342df9 146 SUPERFAMILY SSF46785 12 143 3.33E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26270 c3e853f0b3bc5a5717c9e8b475342df9 146 Pfam PF01047 MarR family 38 93 5.5E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS09920 1a17698cfabd0b749cfa2b180f28d49b 527 SUPERFAMILY SSF52096 254 526 8.44E-90 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS09920 1a17698cfabd0b749cfa2b180f28d49b 527 Pfam PF01039 Carboxyl transferase domain 40 524 5.2E-196 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS09920 1a17698cfabd0b749cfa2b180f28d49b 527 Gene3D G3DSA:3.90.226.10 267 526 8.3E-102 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS09920 1a17698cfabd0b749cfa2b180f28d49b 527 SUPERFAMILY SSF52096 14 267 1.04E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS09920 1a17698cfabd0b749cfa2b180f28d49b 527 Gene3D G3DSA:3.90.226.10 21 266 2.3E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS15900 73147041b624d1b16122401fbb1b5ee8 228 Gene3D G3DSA:3.30.870.10 35 127 6.7E-4 T 06-07-2017 SMD11_RS15900 73147041b624d1b16122401fbb1b5ee8 228 SUPERFAMILY SSF46894 146 203 2.89E-12 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS15900 73147041b624d1b16122401fbb1b5ee8 228 SMART SM00421 138 196 8.5E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS15900 73147041b624d1b16122401fbb1b5ee8 228 Gene3D G3DSA:1.10.10.10 146 202 1.4E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15900 73147041b624d1b16122401fbb1b5ee8 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 192 2.0E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS21925 2b608f14fe7fc7f0423a06a635853989 648 Gene3D G3DSA:3.50.50.60 37 277 7.3E-77 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS21925 2b608f14fe7fc7f0423a06a635853989 648 Gene3D G3DSA:3.50.50.60 409 461 7.3E-77 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS21925 2b608f14fe7fc7f0423a06a635853989 648 Gene3D G3DSA:1.20.58.100 484 599 1.1E-29 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS21925 2b608f14fe7fc7f0423a06a635853989 648 SUPERFAMILY SSF56425 272 414 9.42E-33 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS21925 2b608f14fe7fc7f0423a06a635853989 648 Pfam PF00890 FAD binding domain 47 452 2.7E-61 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS21925 2b608f14fe7fc7f0423a06a635853989 648 Pfam PF02910 Fumarate reductase flavoprotein C-term 513 647 8.5E-33 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS21925 2b608f14fe7fc7f0423a06a635853989 648 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 47 647 0.0 T 06-07-2017 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 SMD11_RS21925 2b608f14fe7fc7f0423a06a635853989 648 SUPERFAMILY SSF46977 504 647 4.97E-37 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS21925 2b608f14fe7fc7f0423a06a635853989 648 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 47 66 9.1E-7 T 06-07-2017 SMD11_RS21925 2b608f14fe7fc7f0423a06a635853989 648 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 416 438 9.1E-7 T 06-07-2017 SMD11_RS21925 2b608f14fe7fc7f0423a06a635853989 648 SUPERFAMILY SSF51905 417 481 2.7E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS21925 2b608f14fe7fc7f0423a06a635853989 648 SUPERFAMILY SSF51905 45 288 2.7E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS21925 2b608f14fe7fc7f0423a06a635853989 648 Gene3D G3DSA:3.90.700.10 278 407 4.8E-18 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS08945 9f43608cbf7874b01de8cb31384ef31f 208 Pfam PF02631 RecX family 69 189 2.5E-27 T 06-07-2017 IPR003783 Regulatory protein RecX GO:0006282 SMD11_RS08945 9f43608cbf7874b01de8cb31384ef31f 208 Hamap MF_01114 Regulatory protein RecX [recX]. 38 194 15.049 T 06-07-2017 IPR003783 Regulatory protein RecX GO:0006282 SMD11_RS08945 9f43608cbf7874b01de8cb31384ef31f 208 Gene3D G3DSA:1.10.10.10 93 134 3.1E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08945 9f43608cbf7874b01de8cb31384ef31f 208 Gene3D G3DSA:1.10.10.10 47 91 6.1E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07040 2c4aeda11108097727d9027df8fbe0e4 770 Pfam PF00664 ABC transporter transmembrane region 219 487 1.3E-21 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS07040 2c4aeda11108097727d9027df8fbe0e4 770 Gene3D G3DSA:3.90.70.10 67 190 8.3E-18 T 06-07-2017 SMD11_RS07040 2c4aeda11108097727d9027df8fbe0e4 770 SMART SM00382 562 746 6.7E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS07040 2c4aeda11108097727d9027df8fbe0e4 770 SUPERFAMILY SSF90123 211 518 4.97E-44 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS07040 2c4aeda11108097727d9027df8fbe0e4 770 TIGRFAM TIGR03796 NHLM_micro_ABC1: NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein 59 767 1.8E-301 T 06-07-2017 IPR022514 NHPM bacteriocin system ABC transporter, peptidase/ATP-binding protein SMD11_RS07040 2c4aeda11108097727d9027df8fbe0e4 770 ProSitePatterns PS00211 ABC transporters family signature. 674 688 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS07040 2c4aeda11108097727d9027df8fbe0e4 770 Gene3D G3DSA:1.20.1560.10 211 512 1.8E-45 T 06-07-2017 SMD11_RS07040 2c4aeda11108097727d9027df8fbe0e4 770 Gene3D G3DSA:3.40.50.300 535 763 2.0E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07040 2c4aeda11108097727d9027df8fbe0e4 770 Pfam PF03412 Peptidase C39 family 60 192 3.5E-36 T 06-07-2017 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 SMD11_RS07040 2c4aeda11108097727d9027df8fbe0e4 770 Pfam PF00005 ABC transporter 553 702 1.4E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS07040 2c4aeda11108097727d9027df8fbe0e4 770 SUPERFAMILY SSF52540 531 768 6.84E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22160 2a12cb689fd1cc9b4e43bff4474839f7 283 Gene3D G3DSA:1.10.260.40 5 68 2.2E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS22160 2a12cb689fd1cc9b4e43bff4474839f7 283 SMART SM00530 17 72 2.4E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS22160 2a12cb689fd1cc9b4e43bff4474839f7 283 Pfam PF13560 Helix-turn-helix domain 13 70 8.3E-11 T 06-07-2017 SMD11_RS22160 2a12cb689fd1cc9b4e43bff4474839f7 283 SUPERFAMILY SSF47413 12 72 2.82E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS33950 a84b1ff4df0acb45cd29a9a5ee92bb57 730 Pfam PF13569 Domain of unknown function (DUF4132) 310 485 1.3E-51 T 06-07-2017 IPR025406 Domain of unknown function DUF4132 SMD11_RS30525 0d0a4f32bb463dda44ce834940a07d14 758 SUPERFAMILY SSF82171 31 468 8.37E-32 T 06-07-2017 SMD11_RS30525 0d0a4f32bb463dda44ce834940a07d14 758 Gene3D G3DSA:2.140.10.30 26 479 4.0E-60 T 06-07-2017 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 SMD11_RS30525 0d0a4f32bb463dda44ce834940a07d14 758 Gene3D G3DSA:3.40.50.1820 481 733 8.5E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30525 0d0a4f32bb463dda44ce834940a07d14 758 SUPERFAMILY SSF53474 481 730 1.36E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30525 0d0a4f32bb463dda44ce834940a07d14 758 Pfam PF00326 Prolyl oligopeptidase family 541 730 3.2E-35 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMD11_RS30525 0d0a4f32bb463dda44ce834940a07d14 758 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 134 451 6.0E-39 T 06-07-2017 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 SMD11_RS17570 72d196bf1f2509be56414791894aa305 191 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 1 182 34.632 T 06-07-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 SMD11_RS17570 72d196bf1f2509be56414791894aa305 191 Pfam PF00692 dUTPase 70 176 3.2E-10 T 06-07-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 SMD11_RS17570 72d196bf1f2509be56414791894aa305 191 SUPERFAMILY SSF51283 2 184 9.55E-57 T 06-07-2017 IPR029054 dUTPase-like SMD11_RS17570 72d196bf1f2509be56414791894aa305 191 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 9.1E-65 T 06-07-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 SMD11_RS17570 72d196bf1f2509be56414791894aa305 191 Gene3D G3DSA:2.70.40.10 2 184 1.3E-67 T 06-07-2017 IPR029054 dUTPase-like SMD11_RS33050 dad0fe03a653087ce24df42aa4d7d38f 392 SUPERFAMILY SSF55874 268 376 1.95E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS33050 dad0fe03a653087ce24df42aa4d7d38f 392 Pfam PF07730 Histidine kinase 177 238 6.1E-9 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS33050 dad0fe03a653087ce24df42aa4d7d38f 392 Gene3D G3DSA:3.30.565.10 271 378 5.1E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS33710 c084f1cf5c2c9672f44cc5b7e4a3ad65 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.7E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS33710 c084f1cf5c2c9672f44cc5b7e4a3ad65 300 Gene3D G3DSA:3.40.190.10 183 268 9.2E-20 T 06-07-2017 SMD11_RS33710 c084f1cf5c2c9672f44cc5b7e4a3ad65 300 Gene3D G3DSA:3.40.190.10 91 182 1.9E-17 T 06-07-2017 SMD11_RS33710 c084f1cf5c2c9672f44cc5b7e4a3ad65 300 SUPERFAMILY SSF46785 1 111 9.25E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33710 c084f1cf5c2c9672f44cc5b7e4a3ad65 300 Gene3D G3DSA:1.10.10.10 1 87 2.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33710 c084f1cf5c2c9672f44cc5b7e4a3ad65 300 Pfam PF03466 LysR substrate binding domain 90 296 5.6E-36 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS33710 c084f1cf5c2c9672f44cc5b7e4a3ad65 300 SUPERFAMILY SSF53850 91 298 4.19E-33 T 06-07-2017 SMD11_RS24065 10ef3c6eb1a933ecd8d329094e58fd0b 321 Pfam PF08279 HTH domain 7 60 6.4E-15 T 06-07-2017 IPR013196 Helix-turn-helix, type 11 SMD11_RS24065 10ef3c6eb1a933ecd8d329094e58fd0b 321 Gene3D G3DSA:1.10.10.10 1 63 1.8E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS24065 10ef3c6eb1a933ecd8d329094e58fd0b 321 SUPERFAMILY SSF46785 3 59 5.03E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS24065 10ef3c6eb1a933ecd8d329094e58fd0b 321 Pfam PF13280 WYL domain 140 315 1.2E-41 T 06-07-2017 IPR026881 WYL domain SMD11_RS05625 d521490d10a63e98a680c585037fc642 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 9.5E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05625 d521490d10a63e98a680c585037fc642 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 9.5E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05625 d521490d10a63e98a680c585037fc642 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 9.5E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05625 d521490d10a63e98a680c585037fc642 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 5.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05625 d521490d10a63e98a680c585037fc642 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 5.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05625 d521490d10a63e98a680c585037fc642 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 5.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05625 d521490d10a63e98a680c585037fc642 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 5.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05625 d521490d10a63e98a680c585037fc642 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 5.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05625 d521490d10a63e98a680c585037fc642 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05625 d521490d10a63e98a680c585037fc642 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS05625 d521490d10a63e98a680c585037fc642 246 SUPERFAMILY SSF51735 6 245 1.35E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05625 d521490d10a63e98a680c585037fc642 246 Gene3D G3DSA:3.40.50.720 5 245 1.0E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05625 d521490d10a63e98a680c585037fc642 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 244 1.4E-55 T 06-07-2017 SMD11_RS19890 ccb800542bc7afefd8c48508fa276f7a 331 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 215 234 1.1E-7 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS19890 ccb800542bc7afefd8c48508fa276f7a 331 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 204 215 1.1E-7 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS19890 ccb800542bc7afefd8c48508fa276f7a 331 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 188 204 1.1E-7 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS19890 ccb800542bc7afefd8c48508fa276f7a 331 Pfam PF13404 AsnC-type helix-turn-helix domain 189 228 9.7E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS19890 ccb800542bc7afefd8c48508fa276f7a 331 Pfam PF13404 AsnC-type helix-turn-helix domain 12 53 9.1E-12 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 SMD11_RS19890 ccb800542bc7afefd8c48508fa276f7a 331 Pfam PF01037 Lrp/AsnC ligand binding domain 259 320 6.2E-7 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS19890 ccb800542bc7afefd8c48508fa276f7a 331 SUPERFAMILY SSF54909 251 325 2.82E-7 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS19890 ccb800542bc7afefd8c48508fa276f7a 331 Gene3D G3DSA:1.10.10.10 12 59 8.2E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19890 ccb800542bc7afefd8c48508fa276f7a 331 Gene3D G3DSA:1.10.10.10 187 235 7.6E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19890 ccb800542bc7afefd8c48508fa276f7a 331 SUPERFAMILY SSF46785 183 247 2.99E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19890 ccb800542bc7afefd8c48508fa276f7a 331 SMART SM00344 189 293 1.4E-6 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD11_RS19890 ccb800542bc7afefd8c48508fa276f7a 331 SMART SM00344 12 117 6.4E-5 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 SMD11_RS19890 ccb800542bc7afefd8c48508fa276f7a 331 Gene3D G3DSA:3.30.70.920 252 325 8.0E-7 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS19890 ccb800542bc7afefd8c48508fa276f7a 331 SUPERFAMILY SSF46785 12 65 8.79E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28975 fe1b677cf09dd2c0846c2060bb45206f 224 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 16 115 1.2E-13 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD11_RS28975 fe1b677cf09dd2c0846c2060bb45206f 224 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 190 1.3E-27 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD11_RS28975 fe1b677cf09dd2c0846c2060bb45206f 224 Gene3D G3DSA:1.20.120.450 2 53 7.7E-10 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase SMD11_RS28975 fe1b677cf09dd2c0846c2060bb45206f 224 SUPERFAMILY SSF109854 2 128 2.14E-17 T 06-07-2017 SMD11_RS31660 455a765d423ab9fb21b000511fb93b19 277 SUPERFAMILY SSF56059 77 261 3.53E-15 T 06-07-2017 SMD11_RS31660 455a765d423ab9fb21b000511fb93b19 277 Gene3D G3DSA:3.30.1490.20 91 163 4.7E-5 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SMD11_RS31660 455a765d423ab9fb21b000511fb93b19 277 Gene3D G3DSA:3.40.50.20 48 90 2.5E-6 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS16115 3219c29cade45632247ab3c20ce166e7 262 SMART SM00448 37 148 2.9E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS16115 3219c29cade45632247ab3c20ce166e7 262 SUPERFAMILY SSF52172 37 218 1.77E-36 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS16115 3219c29cade45632247ab3c20ce166e7 262 Pfam PF00486 Transcriptional regulatory protein, C terminal 184 257 2.2E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS16115 3219c29cade45632247ab3c20ce166e7 262 Pfam PF00072 Response regulator receiver domain 39 148 1.2E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS16115 3219c29cade45632247ab3c20ce166e7 262 Gene3D G3DSA:3.40.50.2300 32 157 2.9E-33 T 06-07-2017 SMD11_RS16115 3219c29cade45632247ab3c20ce166e7 262 SMART SM00862 184 258 5.6E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS16115 3219c29cade45632247ab3c20ce166e7 262 Gene3D G3DSA:1.10.10.10 161 260 5.2E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32095 3aaef7a03a3d4af5b50688e0a975b258 215 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 116 149 3.1E-8 T 06-07-2017 IPR001451 Hexapeptide repeat SMD11_RS32095 3aaef7a03a3d4af5b50688e0a975b258 215 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 125 153 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 SMD11_RS32095 3aaef7a03a3d4af5b50688e0a975b258 215 Gene3D G3DSA:2.160.10.10 30 210 1.7E-45 T 06-07-2017 SMD11_RS32095 3aaef7a03a3d4af5b50688e0a975b258 215 SUPERFAMILY SSF51161 59 207 7.21E-41 T 06-07-2017 IPR011004 Trimeric LpxA-like SMD11_RS16525 6b4343747b274e158acf937932a02d09 300 Pfam PF01435 Peptidase family M48 76 291 7.2E-35 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMD11_RS16525 6b4343747b274e158acf937932a02d09 300 Gene3D G3DSA:3.30.2010.10 68 159 1.0E-33 T 06-07-2017 SMD11_RS16525 6b4343747b274e158acf937932a02d09 300 Hamap MF_00188 Protease HtpX [htpX]. 8 293 24.971 T 06-07-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 SMD11_RS01730 531870d4123f5b2439ece0b4d1e57fcc 398 Gene3D G3DSA:1.10.630.10 2 396 3.7E-139 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS01730 531870d4123f5b2439ece0b4d1e57fcc 398 SUPERFAMILY SSF48264 6 396 3.8E-107 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS01730 531870d4123f5b2439ece0b4d1e57fcc 398 Pfam PF00067 Cytochrome P450 198 365 5.4E-27 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS01730 531870d4123f5b2439ece0b4d1e57fcc 398 PRINTS PR00359 B-class P450 signature 131 147 2.2E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01730 531870d4123f5b2439ece0b4d1e57fcc 398 PRINTS PR00359 B-class P450 signature 312 327 2.2E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01730 531870d4123f5b2439ece0b4d1e57fcc 398 PRINTS PR00359 B-class P450 signature 148 163 2.2E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01730 531870d4123f5b2439ece0b4d1e57fcc 398 PRINTS PR00359 B-class P450 signature 184 206 2.2E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01730 531870d4123f5b2439ece0b4d1e57fcc 398 PRINTS PR00359 B-class P450 signature 85 96 2.2E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01730 531870d4123f5b2439ece0b4d1e57fcc 398 PRINTS PR00359 B-class P450 signature 266 277 2.2E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01730 531870d4123f5b2439ece0b4d1e57fcc 398 PRINTS PR00359 B-class P450 signature 335 344 2.2E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01730 531870d4123f5b2439ece0b4d1e57fcc 398 PRINTS PR00359 B-class P450 signature 344 355 2.2E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01730 531870d4123f5b2439ece0b4d1e57fcc 398 PRINTS PR00359 B-class P450 signature 284 311 2.2E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01730 531870d4123f5b2439ece0b4d1e57fcc 398 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 337 346 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS20365 073fd5a2745c0f6a594f62fe1ff5944d 67 SUPERFAMILY SSF51735 5 53 1.18E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20365 073fd5a2745c0f6a594f62fe1ff5944d 67 Gene3D G3DSA:3.40.50.720 5 55 5.0E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20365 073fd5a2745c0f6a594f62fe1ff5944d 67 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 33 52 4.4E-5 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS20365 073fd5a2745c0f6a594f62fe1ff5944d 67 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 7 26 4.4E-5 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 SMD11_RS20365 073fd5a2745c0f6a594f62fe1ff5944d 67 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 53 1.2E-13 T 06-07-2017 SMD11_RS09415 1ce0656760a04cf4fa9de043e493bbf9 554 Gene3D G3DSA:2.20.28.20 144 174 4.2E-4 T 06-07-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 SMD11_RS09415 1ce0656760a04cf4fa9de043e493bbf9 554 Gene3D G3DSA:1.10.730.10 404 522 5.5E-11 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS09415 1ce0656760a04cf4fa9de043e493bbf9 554 SUPERFAMILY SSF47323 397 513 4.3E-8 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS09415 1ce0656760a04cf4fa9de043e493bbf9 554 Gene3D G3DSA:3.40.50.620 5 143 2.4E-51 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS09415 1ce0656760a04cf4fa9de043e493bbf9 554 Gene3D G3DSA:3.40.50.620 181 382 2.4E-51 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS09415 1ce0656760a04cf4fa9de043e493bbf9 554 PRINTS PR01041 Methionyl-tRNA synthetase signature 250 261 3.4E-6 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD11_RS09415 1ce0656760a04cf4fa9de043e493bbf9 554 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 3.4E-6 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD11_RS09415 1ce0656760a04cf4fa9de043e493bbf9 554 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 3.4E-6 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD11_RS09415 1ce0656760a04cf4fa9de043e493bbf9 554 PRINTS PR01041 Methionyl-tRNA synthetase signature 289 304 3.4E-6 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SMD11_RS09415 1ce0656760a04cf4fa9de043e493bbf9 554 SUPERFAMILY SSF52374 174 379 9.21E-60 T 06-07-2017 SMD11_RS09415 1ce0656760a04cf4fa9de043e493bbf9 554 SUPERFAMILY SSF52374 5 140 9.21E-60 T 06-07-2017 SMD11_RS09415 1ce0656760a04cf4fa9de043e493bbf9 554 Pfam PF09334 tRNA synthetases class I (M) 6 389 1.0E-81 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS09415 1ce0656760a04cf4fa9de043e493bbf9 554 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 23 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS11140 2b9a8896abaecbd2f13d90e9b7a69e26 127 Gene3D G3DSA:3.30.565.10 27 117 3.9E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS11140 2b9a8896abaecbd2f13d90e9b7a69e26 127 Pfam PF13581 Histidine kinase-like ATPase domain 11 118 2.2E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS11140 2b9a8896abaecbd2f13d90e9b7a69e26 127 SUPERFAMILY SSF55874 26 117 9.17E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS09575 bab2900cb4da444dd4d78710facb1fd7 355 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 164 176 3.8E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09575 bab2900cb4da444dd4d78710facb1fd7 355 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 79 95 3.8E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09575 bab2900cb4da444dd4d78710facb1fd7 355 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 212 231 3.8E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09575 bab2900cb4da444dd4d78710facb1fd7 355 Pfam PF00717 Peptidase S24-like 86 128 1.2E-11 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B SMD11_RS09575 bab2900cb4da444dd4d78710facb1fd7 355 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 65 258 3.5E-41 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09575 bab2900cb4da444dd4d78710facb1fd7 355 Gene3D G3DSA:2.10.109.10 76 125 1.4E-40 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain SMD11_RS09575 bab2900cb4da444dd4d78710facb1fd7 355 Gene3D G3DSA:2.10.109.10 158 174 1.4E-40 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain SMD11_RS09575 bab2900cb4da444dd4d78710facb1fd7 355 Gene3D G3DSA:2.10.109.10 212 268 1.4E-40 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain SMD11_RS09575 bab2900cb4da444dd4d78710facb1fd7 355 Pfam PF10502 Signal peptidase, peptidase S26 160 252 2.6E-9 T 06-07-2017 IPR019533 Peptidase S26 SMD11_RS09575 bab2900cb4da444dd4d78710facb1fd7 355 ProSitePatterns PS00761 Signal peptidases I signature 3. 217 230 - T 06-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 SMD11_RS09575 bab2900cb4da444dd4d78710facb1fd7 355 SUPERFAMILY SSF51306 159 264 4.39E-49 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C SMD11_RS09575 bab2900cb4da444dd4d78710facb1fd7 355 SUPERFAMILY SSF51306 78 126 4.39E-49 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C SMD11_RS20545 7aec63df832e1a9fd52539f5a5e0a299 269 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 230 266 3.2E-5 T 06-07-2017 IPR019931 LPXTG cell wall anchor domain SMD11_RS21785 78afb79e67c56367bda26fa0c524996c 1280 SUPERFAMILY SSF90123 32 348 6.41E-69 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS21785 78afb79e67c56367bda26fa0c524996c 1280 Pfam PF00664 ABC transporter transmembrane region 722 992 3.6E-39 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS21785 78afb79e67c56367bda26fa0c524996c 1280 Pfam PF00664 ABC transporter transmembrane region 46 314 1.2E-33 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS21785 78afb79e67c56367bda26fa0c524996c 1280 SMART SM00382 386 572 6.2E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS21785 78afb79e67c56367bda26fa0c524996c 1280 SMART SM00382 1063 1249 6.7E-20 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS21785 78afb79e67c56367bda26fa0c524996c 1280 SUPERFAMILY SSF90123 710 1023 1.83E-72 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS21785 78afb79e67c56367bda26fa0c524996c 1280 Pfam PF00005 ABC transporter 377 526 1.0E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS21785 78afb79e67c56367bda26fa0c524996c 1280 Pfam PF00005 ABC transporter 1055 1203 2.6E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS21785 78afb79e67c56367bda26fa0c524996c 1280 SUPERFAMILY SSF52540 356 593 5.66E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21785 78afb79e67c56367bda26fa0c524996c 1280 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS21785 78afb79e67c56367bda26fa0c524996c 1280 SUPERFAMILY SSF52540 1030 1272 2.17E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21785 78afb79e67c56367bda26fa0c524996c 1280 Gene3D G3DSA:3.40.50.300 360 590 2.4E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21785 78afb79e67c56367bda26fa0c524996c 1280 Gene3D G3DSA:3.40.50.300 1037 1267 1.6E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21785 78afb79e67c56367bda26fa0c524996c 1280 Gene3D G3DSA:1.20.1560.10 32 346 9.5E-66 T 06-07-2017 SMD11_RS21785 78afb79e67c56367bda26fa0c524996c 1280 Gene3D G3DSA:1.20.1560.10 710 1023 1.4E-76 T 06-07-2017 SMD11_RS18325 6fcd4e93769e2ee9886757c8b7c38008 397 Pfam PF01139 tRNA-splicing ligase RtcB 29 397 2.0E-131 T 06-07-2017 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 SMD11_RS18325 6fcd4e93769e2ee9886757c8b7c38008 397 SUPERFAMILY SSF103365 10 397 8.37E-130 T 06-07-2017 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 SMD11_RS32385 5a9a02adc9db051e7bba5c3788f991d2 411 SUPERFAMILY SSF52266 188 398 1.21E-26 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS32385 5a9a02adc9db051e7bba5c3788f991d2 411 Gene3D G3DSA:3.40.50.1110 192 396 2.3E-10 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS32385 5a9a02adc9db051e7bba5c3788f991d2 411 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 194 293 9.3E-12 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS19165 70bef443e2add2c8b8678357834abc4b 403 Gene3D G3DSA:3.40.50.1820 86 382 5.9E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS19165 70bef443e2add2c8b8678357834abc4b 403 SUPERFAMILY SSF53474 88 381 1.0E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS19165 70bef443e2add2c8b8678357834abc4b 403 Pfam PF12697 Alpha/beta hydrolase family 118 373 1.1E-20 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS16495 6c09cc8330e02d0ee058de4ec6a6b484 363 SMART SM00382 36 219 7.4E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS16495 6c09cc8330e02d0ee058de4ec6a6b484 363 Gene3D G3DSA:3.40.50.300 11 237 2.7E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16495 6c09cc8330e02d0ee058de4ec6a6b484 363 SUPERFAMILY SSF52540 12 233 1.41E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16495 6c09cc8330e02d0ee058de4ec6a6b484 363 Pfam PF00005 ABC transporter 28 171 5.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS21640 73e0919e42ce8e7d960ce1d88380f590 200 SUPERFAMILY SSF53254 6 199 8.57E-49 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS21640 73e0919e42ce8e7d960ce1d88380f590 200 Gene3D G3DSA:3.40.50.1240 4 200 1.3E-47 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS21640 73e0919e42ce8e7d960ce1d88380f590 200 SMART SM00855 7 156 5.7E-22 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS21640 73e0919e42ce8e7d960ce1d88380f590 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 196 7.6E-51 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS12595 d3e2968ad4645bbfdef1abefd2aec2a2 487 Gene3D G3DSA:3.90.1310.10 72 142 2.5E-6 T 06-07-2017 SMD11_RS12595 d3e2968ad4645bbfdef1abefd2aec2a2 487 Gene3D G3DSA:3.40.710.10 143 486 1.6E-90 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS12595 d3e2968ad4645bbfdef1abefd2aec2a2 487 Pfam PF00905 Penicillin binding protein transpeptidase domain 155 482 7.5E-67 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD11_RS12595 d3e2968ad4645bbfdef1abefd2aec2a2 487 SUPERFAMILY SSF56601 138 485 9.95E-83 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS11900 530131442d1ecae8ab731524956b2324 278 Pfam PF13371 Tetratricopeptide repeat 196 278 2.3E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS11900 530131442d1ecae8ab731524956b2324 278 Pfam PF13369 Transglutaminase-like superfamily 47 194 3.5E-42 T 06-07-2017 IPR032698 Protein SirB1, N-terminal SMD11_RS26580 f4200e238918d4f60cf9a8aca590f988 93 Pfam PF02416 mttA/Hcf106 family 5 55 6.7E-18 T 06-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 SMD11_RS26580 f4200e238918d4f60cf9a8aca590f988 93 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 68 19.596 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 SMD11_RS26580 f4200e238918d4f60cf9a8aca590f988 93 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 50 2.5E-18 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 SMD11_RS10030 dcc72a58be53d7245fcd04bce811429a 173 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 40 3.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS10030 dcc72a58be53d7245fcd04bce811429a 173 Gene3D G3DSA:1.10.357.10 2 168 7.3E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS10030 dcc72a58be53d7245fcd04bce811429a 173 SUPERFAMILY SSF48498 60 169 4.45E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS10030 dcc72a58be53d7245fcd04bce811429a 173 SUPERFAMILY SSF46689 2 57 1.28E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS14495 859ab18b0422e855a737696dffb5bebb 136 Gene3D G3DSA:3.10.180.10 21 128 9.8E-12 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS14495 859ab18b0422e855a737696dffb5bebb 136 SUPERFAMILY SSF54593 16 129 2.61E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS30345 f021e8f4a50b594e37187407764e4396 326 Gene3D G3DSA:1.10.10.10 3 65 5.4E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30345 f021e8f4a50b594e37187407764e4396 326 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMD11_RS30345 f021e8f4a50b594e37187407764e4396 326 PIRSF PIRSF016838 2 322 5.4E-24 T 06-07-2017 IPR028349 Protein PafC SMD11_RS30345 f021e8f4a50b594e37187407764e4396 326 SUPERFAMILY SSF46785 7 64 1.04E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30345 f021e8f4a50b594e37187407764e4396 326 Pfam PF08279 HTH domain 7 62 1.8E-16 T 06-07-2017 IPR013196 Helix-turn-helix, type 11 SMD11_RS30345 f021e8f4a50b594e37187407764e4396 326 Pfam PF13280 WYL domain 140 312 8.8E-25 T 06-07-2017 IPR026881 WYL domain SMD11_RS12185 ac82f4d0284210b9dc2b6ceae9365967 228 SUPERFAMILY SSF159234 41 210 1.27E-45 T 06-07-2017 SMD11_RS12185 ac82f4d0284210b9dc2b6ceae9365967 228 Pfam PF04167 Protein of unknown function (DUF402) 98 162 1.0E-16 T 06-07-2017 IPR007295 Domain of unknown function DUF402 SMD11_RS12185 ac82f4d0284210b9dc2b6ceae9365967 228 Gene3D G3DSA:2.40.380.10 17 208 1.2E-76 T 06-07-2017 IPR007295 Domain of unknown function DUF402 SMD11_RS29280 660298fc7ac7b4bb4fd62bfc82415e06 497 Gene3D G3DSA:1.20.1250.20 253 409 1.7E-20 T 06-07-2017 SMD11_RS29280 660298fc7ac7b4bb4fd62bfc82415e06 497 Gene3D G3DSA:1.20.1250.20 464 488 1.7E-20 T 06-07-2017 SMD11_RS29280 660298fc7ac7b4bb4fd62bfc82415e06 497 SUPERFAMILY SSF103473 237 408 1.83E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS29280 660298fc7ac7b4bb4fd62bfc82415e06 497 SUPERFAMILY SSF103473 463 489 1.83E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS29280 660298fc7ac7b4bb4fd62bfc82415e06 497 SUPERFAMILY SSF103473 2 188 1.83E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS29280 660298fc7ac7b4bb4fd62bfc82415e06 497 Pfam PF07690 Major Facilitator Superfamily 6 398 5.2E-49 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS29280 660298fc7ac7b4bb4fd62bfc82415e06 497 PRINTS PR01036 Tetracycline resistance protein TetB signature 129 153 1.4E-5 T 06-07-2017 SMD11_RS29280 660298fc7ac7b4bb4fd62bfc82415e06 497 PRINTS PR01036 Tetracycline resistance protein TetB signature 389 408 1.4E-5 T 06-07-2017 SMD11_RS29280 660298fc7ac7b4bb4fd62bfc82415e06 497 PRINTS PR01036 Tetracycline resistance protein TetB signature 4 28 1.4E-5 T 06-07-2017 SMD11_RS29280 660298fc7ac7b4bb4fd62bfc82415e06 497 Gene3D G3DSA:1.20.1250.20 2 184 6.0E-27 T 06-07-2017 SMD11_RS13355 550d62dfaab734c7b0096640871f7155 98 Gene3D G3DSA:1.20.59.10 16 81 2.4E-8 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD11_RS13355 550d62dfaab734c7b0096640871f7155 98 SMART SM00830 27 90 3.6E-4 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD11_RS13355 550d62dfaab734c7b0096640871f7155 98 Pfam PF01817 Chorismate mutase type II 27 77 7.4E-6 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD11_RS13355 550d62dfaab734c7b0096640871f7155 98 SUPERFAMILY SSF48600 23 82 2.56E-9 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SMD11_RS13355 550d62dfaab734c7b0096640871f7155 98 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 26 96 2.4E-15 T 06-07-2017 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal SMD11_RS24270 4c3ed21b1a3d76ed9e2b9ba9af2150fc 351 Pfam PF00877 NlpC/P60 family 252 341 1.1E-25 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS24270 4c3ed21b1a3d76ed9e2b9ba9af2150fc 351 Gene3D G3DSA:3.90.1720.10 234 341 2.2E-40 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS24270 4c3ed21b1a3d76ed9e2b9ba9af2150fc 351 SUPERFAMILY SSF54001 234 341 2.7E-36 T 06-07-2017 SMD11_RS18100 0b395b169e55b3cf8226898d0a23844d 443 Pfam PF09594 Protein of unknown function (DUF2029) 53 146 4.4E-5 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 SMD11_RS18100 0b395b169e55b3cf8226898d0a23844d 443 Pfam PF13367 Protease prsW family 103 306 2.7E-52 T 06-07-2017 IPR026898 Protease PrsW GO:0008233 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 262 316 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 Gene3D G3DSA:1.20.210.10 25 551 1.1E-193 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 42 484 2.7E-144 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 SUPERFAMILY SSF81442 30 540 5.49E-175 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 33 537 1.2E-213 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 PRINTS PR01165 Cytochrome c oxidase subunit I signature 106 130 6.6E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 PRINTS PR01165 Cytochrome c oxidase subunit I signature 306 321 6.6E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 PRINTS PR01165 Cytochrome c oxidase subunit I signature 239 260 6.6E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 PRINTS PR01165 Cytochrome c oxidase subunit I signature 260 281 6.6E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 PRINTS PR01165 Cytochrome c oxidase subunit I signature 328 349 6.6E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 PRINTS PR01165 Cytochrome c oxidase subunit I signature 363 381 6.6E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 PRINTS PR01165 Cytochrome c oxidase subunit I signature 181 199 6.6E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 PRINTS PR01165 Cytochrome c oxidase subunit I signature 149 161 6.6E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 PRINTS PR01165 Cytochrome c oxidase subunit I signature 391 410 6.6E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 PRINTS PR01165 Cytochrome c oxidase subunit I signature 32 57 6.6E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 PRINTS PR01165 Cytochrome c oxidase subunit I signature 79 102 6.6E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 PRINTS PR01165 Cytochrome c oxidase subunit I signature 210 229 6.6E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24195 21892bff08f3d5c9376daa31b9ffcceb 575 PRINTS PR01165 Cytochrome c oxidase subunit I signature 441 462 6.6E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS08310 23e2a328ea8032ca15e78e0c27fe43b7 70 Pfam PF04149 Domain of unknown function (DUF397) 9 62 1.9E-20 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS15950 87a6fc738af49c81c2c0da4c6b549aeb 412 Gene3D G3DSA:3.50.50.60 2 104 4.5E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15950 87a6fc738af49c81c2c0da4c6b549aeb 412 SUPERFAMILY SSF51905 146 310 9.21E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15950 87a6fc738af49c81c2c0da4c6b549aeb 412 Gene3D G3DSA:3.50.50.60 105 309 8.1E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15950 87a6fc738af49c81c2c0da4c6b549aeb 412 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 287 4.4E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15950 87a6fc738af49c81c2c0da4c6b549aeb 412 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 5.0E-16 T 06-07-2017 SMD11_RS15950 87a6fc738af49c81c2c0da4c6b549aeb 412 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 5.0E-16 T 06-07-2017 SMD11_RS15950 87a6fc738af49c81c2c0da4c6b549aeb 412 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 5.0E-16 T 06-07-2017 SMD11_RS15950 87a6fc738af49c81c2c0da4c6b549aeb 412 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 5.0E-16 T 06-07-2017 SMD11_RS15950 87a6fc738af49c81c2c0da4c6b549aeb 412 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 5.0E-16 T 06-07-2017 SMD11_RS15950 87a6fc738af49c81c2c0da4c6b549aeb 412 SUPERFAMILY SSF51905 2 191 4.61E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07000 564b5dea9ea681d23be803d669af70d0 613 Gene3D G3DSA:3.40.50.980 262 418 5.1E-24 T 06-07-2017 SMD11_RS07000 564b5dea9ea681d23be803d669af70d0 613 Pfam PF13193 AMP-binding enzyme C-terminal domain 512 589 2.2E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS07000 564b5dea9ea681d23be803d669af70d0 613 Gene3D G3DSA:2.30.38.10 419 497 6.3E-16 T 06-07-2017 SMD11_RS07000 564b5dea9ea681d23be803d669af70d0 613 Gene3D G3DSA:3.40.50.980 58 164 6.3E-22 T 06-07-2017 SMD11_RS07000 564b5dea9ea681d23be803d669af70d0 613 Gene3D G3DSA:3.40.50.980 239 261 6.3E-22 T 06-07-2017 SMD11_RS07000 564b5dea9ea681d23be803d669af70d0 613 Gene3D G3DSA:3.30.300.30 502 600 1.3E-22 T 06-07-2017 SMD11_RS07000 564b5dea9ea681d23be803d669af70d0 613 Pfam PF00501 AMP-binding enzyme 58 503 8.2E-68 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS07000 564b5dea9ea681d23be803d669af70d0 613 SUPERFAMILY SSF56801 223 599 1.16E-121 T 06-07-2017 SMD11_RS07000 564b5dea9ea681d23be803d669af70d0 613 SUPERFAMILY SSF56801 23 184 1.16E-121 T 06-07-2017 SMD11_RS05480 f16f54a84eeda0dce3b573cb8217058e 404 PIRSF PIRSF000429 2 404 6.6E-108 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS05480 f16f54a84eeda0dce3b573cb8217058e 404 Gene3D G3DSA:3.40.47.10 288 403 9.9E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS05480 f16f54a84eeda0dce3b573cb8217058e 404 Gene3D G3DSA:3.40.47.10 149 186 9.9E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS05480 f16f54a84eeda0dce3b573cb8217058e 404 Gene3D G3DSA:3.40.47.10 187 287 3.3E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS05480 f16f54a84eeda0dce3b573cb8217058e 404 Gene3D G3DSA:3.40.47.10 5 128 3.3E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS05480 f16f54a84eeda0dce3b573cb8217058e 404 ProSitePatterns PS00737 Thiolases signature 2. 350 366 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SMD11_RS05480 f16f54a84eeda0dce3b573cb8217058e 404 SUPERFAMILY SSF53901 3 277 4.26E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS05480 f16f54a84eeda0dce3b573cb8217058e 404 SUPERFAMILY SSF53901 282 403 2.53E-44 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS05480 f16f54a84eeda0dce3b573cb8217058e 404 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 402 2.6E-133 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 SMD11_RS05480 f16f54a84eeda0dce3b573cb8217058e 404 Pfam PF00108 Thiolase, N-terminal domain 7 230 8.7E-42 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SMD11_RS05480 f16f54a84eeda0dce3b573cb8217058e 404 Pfam PF02803 Thiolase, C-terminal domain 282 403 3.3E-46 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SMD11_RS05480 f16f54a84eeda0dce3b573cb8217058e 404 ProSitePatterns PS00099 Thiolases active site. 385 398 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SMD11_RS22750 33a4b14b41237b53e6540e64e9658e8e 261 SUPERFAMILY SSF56784 88 258 7.32E-19 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS22750 33a4b14b41237b53e6540e64e9658e8e 261 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 72 260 3.0E-34 T 06-07-2017 IPR005519 Acid phosphatase, class B-like SMD11_RS22750 33a4b14b41237b53e6540e64e9658e8e 261 PIRSF PIRSF002674 9 261 9.0E-53 T 06-07-2017 IPR014403 Vegetative storage protein/acid phosphatase SMD11_RS22750 33a4b14b41237b53e6540e64e9658e8e 261 Gene3D G3DSA:3.40.50.1000 82 246 3.0E-19 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS28215 aa77f501ad1670623b93de335c4aea85 500 SUPERFAMILY SSF55931 36 465 2.65E-48 T 06-07-2017 SMD11_RS28215 aa77f501ad1670623b93de335c4aea85 500 PIRSF PIRSF012666 1 498 9.4E-219 T 06-07-2017 IPR016602 Uncharacterised conserved protein UCP012666 SMD11_RS31095 67d3b66d4f92748a50140cb4ff469d62 671 Gene3D G3DSA:3.40.390.10 260 340 1.3E-6 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD11_RS31095 67d3b66d4f92748a50140cb4ff469d62 671 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 91 397 6.2E-36 T 06-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMD11_RS03825 e50b53032af69243765b867602d8e410 299 Gene3D G3DSA:3.40.50.720 3 250 5.1E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03825 e50b53032af69243765b867602d8e410 299 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.5E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03825 e50b53032af69243765b867602d8e410 299 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.5E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03825 e50b53032af69243765b867602d8e410 299 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.5E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03825 e50b53032af69243765b867602d8e410 299 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 188 0.0065 T 06-07-2017 SMD11_RS03825 e50b53032af69243765b867602d8e410 299 Pfam PF00106 short chain dehydrogenase 3 192 1.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03825 e50b53032af69243765b867602d8e410 299 SUPERFAMILY SSF51735 2 248 2.61E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03825 e50b53032af69243765b867602d8e410 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.1E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03825 e50b53032af69243765b867602d8e410 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.1E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03825 e50b53032af69243765b867602d8e410 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.1E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS03825 e50b53032af69243765b867602d8e410 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.1E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS31755 0332f49e138befcb26f6fc439d7c2588 439 Gene3D G3DSA:3.40.50.720 1 207 2.5E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS31755 0332f49e138befcb26f6fc439d7c2588 439 SUPERFAMILY SSF51735 1 178 4.04E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS31755 0332f49e138befcb26f6fc439d7c2588 439 SUPERFAMILY SSF52413 312 432 9.02E-33 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD11_RS31755 0332f49e138befcb26f6fc439d7c2588 439 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 419 1.9E-121 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMD11_RS31755 0332f49e138befcb26f6fc439d7c2588 439 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 205 297 2.0E-28 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD11_RS31755 0332f49e138befcb26f6fc439d7c2588 439 SMART SM00984 322 423 3.0E-36 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD11_RS31755 0332f49e138befcb26f6fc439d7c2588 439 PIRSF PIRSF000124 1 438 3.4E-115 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SMD11_RS31755 0332f49e138befcb26f6fc439d7c2588 439 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 423 1.4E-24 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD11_RS31755 0332f49e138befcb26f6fc439d7c2588 439 Gene3D G3DSA:3.40.50.720 235 437 1.1E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS31755 0332f49e138befcb26f6fc439d7c2588 439 SUPERFAMILY SSF48179 204 303 7.82E-26 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS31755 0332f49e138befcb26f6fc439d7c2588 439 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 179 4.0E-52 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SMD11_RS31755 0332f49e138befcb26f6fc439d7c2588 439 PIRSF PIRSF500134 1 439 9.3E-144 T 06-07-2017 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 SMD11_RS31755 0332f49e138befcb26f6fc439d7c2588 439 Gene3D G3DSA:1.20.5.100 208 233 2.4E-15 T 06-07-2017 SMD11_RS05460 855582734a667ab423eb56ae13e3c3ba 502 SUPERFAMILY SSF63737 33 224 2.09E-36 T 06-07-2017 SMD11_RS05460 855582734a667ab423eb56ae13e3c3ba 502 Gene3D G3DSA:1.10.390.10 328 461 6.5E-23 T 06-07-2017 SMD11_RS05460 855582734a667ab423eb56ae13e3c3ba 502 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 314 329 6.0E-12 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS05460 855582734a667ab423eb56ae13e3c3ba 502 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 161 176 6.0E-12 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS05460 855582734a667ab423eb56ae13e3c3ba 502 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 208 223 6.0E-12 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS05460 855582734a667ab423eb56ae13e3c3ba 502 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 333 345 6.0E-12 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS05460 855582734a667ab423eb56ae13e3c3ba 502 SUPERFAMILY SSF55486 245 461 4.03E-49 T 06-07-2017 SMD11_RS05460 855582734a667ab423eb56ae13e3c3ba 502 Pfam PF01433 Peptidase family M1 310 370 4.2E-18 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS05460 855582734a667ab423eb56ae13e3c3ba 502 Pfam PF01433 Peptidase family M1 48 277 7.6E-26 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS10445 872f55cc950d3ced67a0d203b08c15b1 449 SUPERFAMILY SSF53850 15 439 2.61E-74 T 06-07-2017 SMD11_RS10445 872f55cc950d3ced67a0d203b08c15b1 449 Pfam PF01547 Bacterial extracellular solute-binding protein 48 354 5.9E-28 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 SMD11_RS10445 872f55cc950d3ced67a0d203b08c15b1 449 Gene3D G3DSA:3.40.190.10 326 388 1.7E-33 T 06-07-2017 SMD11_RS10445 872f55cc950d3ced67a0d203b08c15b1 449 Gene3D G3DSA:3.40.190.10 23 155 1.7E-33 T 06-07-2017 SMD11_RS13105 019144c3ae433724d35a2a9472eb7736 198 SUPERFAMILY SSF55144 5 174 3.92E-31 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase SMD11_RS13105 019144c3ae433724d35a2a9472eb7736 198 Gene3D G3DSA:3.90.1140.10 8 176 2.8E-23 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase SMD11_RS13105 019144c3ae433724d35a2a9472eb7736 198 Pfam PF13563 2'-5' RNA ligase superfamily 13 158 5.1E-22 T 06-07-2017 SMD11_RS06495 f6bd4a14def54a0a01c687cb6e5ccafc 670 SUPERFAMILY SSF51703 4 492 7.06E-162 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS06495 f6bd4a14def54a0a01c687cb6e5ccafc 670 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 6 496 1.6E-139 T 06-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS06495 f6bd4a14def54a0a01c687cb6e5ccafc 670 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 531 660 1.3E-39 T 06-07-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS06495 f6bd4a14def54a0a01c687cb6e5ccafc 670 Gene3D G3DSA:3.20.20.240 4 491 3.5E-186 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS06495 f6bd4a14def54a0a01c687cb6e5ccafc 670 SUPERFAMILY SSF52242 514 653 4.32E-43 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD11_RS06495 f6bd4a14def54a0a01c687cb6e5ccafc 670 Pfam PF01642 Methylmalonyl-CoA mutase 4 490 4.8E-132 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS06495 f6bd4a14def54a0a01c687cb6e5ccafc 670 Gene3D G3DSA:3.40.50.280 511 659 1.6E-48 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD11_RS06495 f6bd4a14def54a0a01c687cb6e5ccafc 670 Pfam PF02310 B12 binding domain 534 639 3.6E-18 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD11_RS11205 6306255f02c46ae863154daaebb182b5 196 SUPERFAMILY SSF55846 21 193 1.92E-22 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS11205 6306255f02c46ae863154daaebb182b5 196 Gene3D G3DSA:3.40.80.10 36 194 1.8E-16 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS11205 6306255f02c46ae863154daaebb182b5 196 SMART SM00644 27 180 2.1E-17 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS11205 6306255f02c46ae863154daaebb182b5 196 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 39 179 6.9E-16 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS18220 a753a54af912d53ecd550834755464cb 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 186 2.3E-27 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS18220 a753a54af912d53ecd550834755464cb 214 SUPERFAMILY SSF56784 2 213 4.41E-51 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS18220 a753a54af912d53ecd550834755464cb 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 61 185 6.1E-16 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SMD11_RS18220 a753a54af912d53ecd550834755464cb 214 Gene3D G3DSA:1.10.150.240 18 83 1.6E-11 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 SMD11_RS18220 a753a54af912d53ecd550834755464cb 214 Gene3D G3DSA:3.40.50.1000 89 213 1.9E-40 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS18220 a753a54af912d53ecd550834755464cb 214 Gene3D G3DSA:3.40.50.1000 1 17 1.9E-40 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS26175 02f11cde379c3fce0f81fa4504f4ef47 244 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 93 238 6.2E-14 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD11_RS26175 02f11cde379c3fce0f81fa4504f4ef47 244 SUPERFAMILY SSF48498 95 241 1.45E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS26175 02f11cde379c3fce0f81fa4504f4ef47 244 Gene3D G3DSA:1.10.357.10 19 242 7.5E-51 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS26175 02f11cde379c3fce0f81fa4504f4ef47 244 SUPERFAMILY SSF46689 22 86 1.41E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS26175 02f11cde379c3fce0f81fa4504f4ef47 244 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 77 6.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS21840 7f33cd04510071351090215197218de0 72 Pfam PF00403 Heavy-metal-associated domain 8 67 3.5E-15 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMD11_RS21840 7f33cd04510071351090215197218de0 72 PRINTS PR00944 Copper ion binding protein signature 5 17 3.3E-5 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 SMD11_RS21840 7f33cd04510071351090215197218de0 72 PRINTS PR00944 Copper ion binding protein signature 55 68 3.3E-5 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 SMD11_RS21840 7f33cd04510071351090215197218de0 72 PRINTS PR00944 Copper ion binding protein signature 17 30 3.3E-5 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 SMD11_RS21840 7f33cd04510071351090215197218de0 72 PRINTS PR00944 Copper ion binding protein signature 43 55 3.3E-5 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 SMD11_RS21840 7f33cd04510071351090215197218de0 72 SUPERFAMILY SSF55008 4 69 1.7E-16 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SMD11_RS21840 7f33cd04510071351090215197218de0 72 Gene3D G3DSA:3.30.70.100 5 68 1.5E-20 T 06-07-2017 SMD11_RS13825 e4c3b8036643522ec2709a174f6532fa 219 Gene3D G3DSA:3.40.50.1000 77 205 1.7E-24 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS13825 e4c3b8036643522ec2709a174f6532fa 219 Gene3D G3DSA:1.10.150.240 24 76 2.6E-10 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 SMD11_RS13825 e4c3b8036643522ec2709a174f6532fa 219 Pfam PF12710 haloacid dehalogenase-like hydrolase 13 165 6.4E-12 T 06-07-2017 SMD11_RS13825 e4c3b8036643522ec2709a174f6532fa 219 SUPERFAMILY SSF56784 12 205 2.52E-35 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS09255 7c11b02db61e30f664a967200b1942da 177 SUPERFAMILY SSF75420 3 85 2.09E-20 T 06-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal SMD11_RS09255 7c11b02db61e30f664a967200b1942da 177 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 155 23.101 T 06-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 SMD11_RS09255 7c11b02db61e30f664a967200b1942da 177 Gene3D G3DSA:3.30.300.70 3 82 1.4E-24 T 06-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal SMD11_RS09255 7c11b02db61e30f664a967200b1942da 177 Pfam PF02576 Putative ribosome maturation factor RimP 12 151 2.6E-35 T 06-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 SMD11_RS09255 7c11b02db61e30f664a967200b1942da 177 SUPERFAMILY SSF74942 86 155 8.76E-5 T 06-07-2017 IPR028998 Ribosome maturation factor RimP, C-terminal SMD11_RS33975 0be480dfe1e6c8fa15d55c7cf6e85737 520 PIRSF PIRSF006060 20 506 1.9E-59 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS33975 0be480dfe1e6c8fa15d55c7cf6e85737 520 Pfam PF13520 Amino acid permease 39 473 1.8E-58 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS33975 0be480dfe1e6c8fa15d55c7cf6e85737 520 ProSitePatterns PS00218 Amino acid permeases signature. 65 96 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD11_RS18080 4637fcdc88f6961ccfb1a8aac5c113ed 476 Gene3D G3DSA:3.90.1530.10 96 157 6.3E-4 T 06-07-2017 SMD11_RS18080 4637fcdc88f6961ccfb1a8aac5c113ed 476 SUPERFAMILY SSF110849 96 157 2.09E-6 T 06-07-2017 IPR003115 ParB/Sulfiredoxin SMD11_RS24335 eb8baf35c83d18dc4729bd6a7c6fc72e 253 Gene3D G3DSA:3.40.1130.10 18 208 2.3E-30 T 06-07-2017 SMD11_RS24335 eb8baf35c83d18dc4729bd6a7c6fc72e 253 Pfam PF01553 Acyltransferase 22 152 1.0E-20 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD11_RS24335 eb8baf35c83d18dc4729bd6a7c6fc72e 253 SMART SM00563 34 155 1.4E-34 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD11_RS24335 eb8baf35c83d18dc4729bd6a7c6fc72e 253 SUPERFAMILY SSF69593 14 223 1.27E-50 T 06-07-2017 SMD11_RS21845 49c130bc0a23641fc58c1370f44198f1 497 Gene3D G3DSA:3.40.605.10 2 260 1.5E-88 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS21845 49c130bc0a23641fc58c1370f44198f1 497 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 4 481 3.5E-247 T 06-07-2017 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 SMD11_RS21845 49c130bc0a23641fc58c1370f44198f1 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS21845 49c130bc0a23641fc58c1370f44198f1 497 Pfam PF00171 Aldehyde dehydrogenase family 16 477 8.8E-135 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS21845 49c130bc0a23641fc58c1370f44198f1 497 SUPERFAMILY SSF53720 2 483 1.19E-143 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS21845 49c130bc0a23641fc58c1370f44198f1 497 Gene3D G3DSA:3.40.309.10 261 442 7.4E-62 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS23350 35975f3725f3db23ffb043d0483a853e 272 Pfam PF03649 Uncharacterised protein family (UPF0014) 15 243 4.8E-42 T 06-07-2017 IPR005226 UPF0014 family SMD11_RS32340 ee88f50a0de21335acf37a03199f7908 285 PRINTS PR00164 ABC-2 type transport system membrane protein signature 134 159 2.5E-8 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS32340 ee88f50a0de21335acf37a03199f7908 285 PRINTS PR00164 ABC-2 type transport system membrane protein signature 208 227 2.5E-8 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS32340 ee88f50a0de21335acf37a03199f7908 285 PRINTS PR00164 ABC-2 type transport system membrane protein signature 228 247 2.5E-8 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS32340 ee88f50a0de21335acf37a03199f7908 285 PRINTS PR00164 ABC-2 type transport system membrane protein signature 54 75 2.5E-8 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS32340 ee88f50a0de21335acf37a03199f7908 285 Pfam PF01061 ABC-2 type transporter 34 249 7.4E-31 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD11_RS32340 ee88f50a0de21335acf37a03199f7908 285 PIRSF PIRSF006648 8 285 7.3E-57 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS06955 995bb1f53fe6d8a3f7b6f5d11725d471 182 SUPERFAMILY SSF158694 9 164 5.62E-36 T 06-07-2017 SMD11_RS06955 995bb1f53fe6d8a3f7b6f5d11725d471 182 TIGRFAM TIGR03180 UraD_2: OHCU decarboxylase 12 165 3.2E-46 T 06-07-2017 IPR017595 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 2 SMD11_RS06955 995bb1f53fe6d8a3f7b6f5d11725d471 182 Gene3D G3DSA:1.10.3330.10 17 166 8.5E-37 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 SMD11_RS06955 995bb1f53fe6d8a3f7b6f5d11725d471 182 Pfam PF09349 OHCU decarboxylase 13 162 8.3E-29 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 SMD11_RS05645 be0217c9848e730c07cb788a66c0f355 401 SUPERFAMILY SSF55874 254 372 8.78E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS05645 be0217c9848e730c07cb788a66c0f355 401 Pfam PF07730 Histidine kinase 183 247 2.7E-16 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS23635 42fc15df0d31554af83a7e04c0b7b199 205 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 121 134 - T 06-07-2017 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMD11_RS23635 42fc15df0d31554af83a7e04c0b7b199 205 Pfam PF01081 KDPG and KHG aldolase 4 196 3.0E-70 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMD11_RS23635 42fc15df0d31554af83a7e04c0b7b199 205 Gene3D G3DSA:3.20.20.70 5 203 6.2E-70 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS23635 42fc15df0d31554af83a7e04c0b7b199 205 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 33 42 - T 06-07-2017 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMD11_RS23635 42fc15df0d31554af83a7e04c0b7b199 205 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 4 202 1.6E-72 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SMD11_RS23635 42fc15df0d31554af83a7e04c0b7b199 205 SUPERFAMILY SSF51569 4 202 1.26E-62 T 06-07-2017 SMD11_RS03025 b2410800a44c3ab0265b70aca63d8f02 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 2.0E-8 T 06-07-2017 SMD11_RS03025 b2410800a44c3ab0265b70aca63d8f02 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 19 38 2.0E-8 T 06-07-2017 SMD11_RS03025 b2410800a44c3ab0265b70aca63d8f02 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 214 232 2.0E-8 T 06-07-2017 SMD11_RS03025 b2410800a44c3ab0265b70aca63d8f02 461 SUPERFAMILY SSF51905 16 237 2.94E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03025 b2410800a44c3ab0265b70aca63d8f02 461 Gene3D G3DSA:3.50.50.60 306 351 3.3E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03025 b2410800a44c3ab0265b70aca63d8f02 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 214 239 1.9E-9 T 06-07-2017 SMD11_RS03025 b2410800a44c3ab0265b70aca63d8f02 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 183 1.9E-9 T 06-07-2017 SMD11_RS03025 b2410800a44c3ab0265b70aca63d8f02 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 18 40 1.9E-9 T 06-07-2017 SMD11_RS03025 b2410800a44c3ab0265b70aca63d8f02 461 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 16 361 1.5E-110 T 06-07-2017 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase SMD11_RS03025 b2410800a44c3ab0265b70aca63d8f02 461 Gene3D G3DSA:3.50.50.60 22 220 6.6E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03025 b2410800a44c3ab0265b70aca63d8f02 461 SUPERFAMILY SSF51905 209 252 7.86E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03025 b2410800a44c3ab0265b70aca63d8f02 461 SUPERFAMILY SSF51905 290 412 7.86E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03025 b2410800a44c3ab0265b70aca63d8f02 461 Gene3D G3DSA:3.50.50.60 352 366 6.5E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS03025 b2410800a44c3ab0265b70aca63d8f02 461 Gene3D G3DSA:3.50.50.60 221 304 6.5E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS18030 4b827dcf4345e56a8c07bab1a6836b9e 401 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 175 371 1.5E-39 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS18030 4b827dcf4345e56a8c07bab1a6836b9e 401 SMART SM00331 149 371 3.4E-24 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS34320 a99d068f8aa2ec7535bdb6c056bc6fc5 790 Pfam PF00550 Phosphopantetheine attachment site 81 140 1.3E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS34320 a99d068f8aa2ec7535bdb6c056bc6fc5 790 SUPERFAMILY SSF51735 196 483 8.64E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS34320 a99d068f8aa2ec7535bdb6c056bc6fc5 790 SMART SM00823 Phosphopantetheine attachment site 74 144 0.0092 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS34320 a99d068f8aa2ec7535bdb6c056bc6fc5 790 Pfam PF07993 Male sterility protein 200 432 4.2E-56 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 SMD11_RS34320 a99d068f8aa2ec7535bdb6c056bc6fc5 790 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 198 523 3.2E-75 T 06-07-2017 IPR010080 Thioester reductase-like domain SMD11_RS34320 a99d068f8aa2ec7535bdb6c056bc6fc5 790 Gene3D G3DSA:1.10.1200.10 73 141 1.3E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS34320 a99d068f8aa2ec7535bdb6c056bc6fc5 790 Gene3D G3DSA:3.40.50.720 197 464 6.4E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS34320 a99d068f8aa2ec7535bdb6c056bc6fc5 790 SUPERFAMILY SSF47336 73 162 3.4E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS10760 7e7e0921280112746214c0385595113e 420 SUPERFAMILY SSF55874 267 382 4.62E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS10760 7e7e0921280112746214c0385595113e 420 Pfam PF07730 Histidine kinase 190 253 1.6E-14 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS25300 7e22894b249ecfe67fdd722432bae67c 223 Gene3D G3DSA:3.40.50.2300 5 158 2.4E-38 T 06-07-2017 SMD11_RS25300 7e22894b249ecfe67fdd722432bae67c 223 SMART SM00421 157 214 9.3E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS25300 7e22894b249ecfe67fdd722432bae67c 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 213 3.7E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS25300 7e22894b249ecfe67fdd722432bae67c 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 6.8E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS25300 7e22894b249ecfe67fdd722432bae67c 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 6.8E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS25300 7e22894b249ecfe67fdd722432bae67c 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 6.8E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS25300 7e22894b249ecfe67fdd722432bae67c 223 Gene3D G3DSA:1.10.10.10 159 218 7.1E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS25300 7e22894b249ecfe67fdd722432bae67c 223 SUPERFAMILY SSF46894 149 221 1.97E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS25300 7e22894b249ecfe67fdd722432bae67c 223 SUPERFAMILY SSF52172 5 133 5.69E-33 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS25300 7e22894b249ecfe67fdd722432bae67c 223 SMART SM00448 7 121 1.1E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS25300 7e22894b249ecfe67fdd722432bae67c 223 Pfam PF00072 Response regulator receiver domain 9 122 3.4E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS03765 a4066454841b30f972d18b422e0110d1 346 Gene3D G3DSA:3.40.50.1820 32 346 1.3E-63 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS03765 a4066454841b30f972d18b422e0110d1 346 Pfam PF00756 Putative esterase 55 338 1.1E-30 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 SMD11_RS03765 a4066454841b30f972d18b422e0110d1 346 SUPERFAMILY SSF53474 298 342 5.87E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS03765 a4066454841b30f972d18b422e0110d1 346 SUPERFAMILY SSF53474 47 185 5.87E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS03765 a4066454841b30f972d18b422e0110d1 346 SUPERFAMILY SSF53474 234 261 5.87E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS13555 d05bf461ca5ab233a776c6369bf9813f 597 Pfam PF02757 YLP motif 150 157 6.3 T 06-07-2017 IPR004019 YLP motif SMD11_RS13555 d05bf461ca5ab233a776c6369bf9813f 597 Pfam PF02757 YLP motif 230 237 6.3 T 06-07-2017 IPR004019 YLP motif SMD11_RS13555 d05bf461ca5ab233a776c6369bf9813f 597 Pfam PF02757 YLP motif 265 272 6.3 T 06-07-2017 IPR004019 YLP motif SMD11_RS13555 d05bf461ca5ab233a776c6369bf9813f 597 Pfam PF02757 YLP motif 245 253 0.82 T 06-07-2017 IPR004019 YLP motif SMD11_RS13555 d05bf461ca5ab233a776c6369bf9813f 597 Pfam PF02757 YLP motif 170 177 6.3 T 06-07-2017 IPR004019 YLP motif SMD11_RS13555 d05bf461ca5ab233a776c6369bf9813f 597 Pfam PF02757 YLP motif 189 196 6.3 T 06-07-2017 IPR004019 YLP motif SMD11_RS13555 d05bf461ca5ab233a776c6369bf9813f 597 Pfam PF02757 YLP motif 113 120 6.3 T 06-07-2017 IPR004019 YLP motif SMD11_RS13555 d05bf461ca5ab233a776c6369bf9813f 597 Pfam PF02757 YLP motif 86 93 6.3 T 06-07-2017 IPR004019 YLP motif SMD11_RS13555 d05bf461ca5ab233a776c6369bf9813f 597 Pfam PF02757 YLP motif 209 216 6.3 T 06-07-2017 IPR004019 YLP motif SMD11_RS13555 d05bf461ca5ab233a776c6369bf9813f 597 Pfam PF02757 YLP motif 285 292 6.3 T 06-07-2017 IPR004019 YLP motif SMD11_RS05930 09459d503c18a484e4d6bc16609e8cd8 669 Gene3D G3DSA:3.20.70.20 3 113 4.4E-96 T 06-07-2017 SMD11_RS05930 09459d503c18a484e4d6bc16609e8cd8 669 Gene3D G3DSA:3.20.70.20 581 624 4.4E-96 T 06-07-2017 SMD11_RS05930 09459d503c18a484e4d6bc16609e8cd8 669 Gene3D G3DSA:3.20.70.20 197 507 4.4E-96 T 06-07-2017 SMD11_RS05930 09459d503c18a484e4d6bc16609e8cd8 669 TIGRFAM TIGR02505 RTPR: ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent 5 669 1.9E-165 T 06-07-2017 IPR013345 Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0006260|GO:0008998|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 SMD11_RS05930 09459d503c18a484e4d6bc16609e8cd8 669 Gene3D G3DSA:3.90.1390.10 625 669 1.5E-20 T 06-07-2017 SMD11_RS05930 09459d503c18a484e4d6bc16609e8cd8 669 Gene3D G3DSA:3.90.1390.10 508 550 1.5E-20 T 06-07-2017 SMD11_RS05930 09459d503c18a484e4d6bc16609e8cd8 669 SUPERFAMILY SSF51998 3 669 5.72E-156 T 06-07-2017 SMD11_RS05930 09459d503c18a484e4d6bc16609e8cd8 669 Pfam PF02867 Ribonucleotide reductase, barrel domain 478 621 3.5E-5 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS05930 09459d503c18a484e4d6bc16609e8cd8 669 Pfam PF02867 Ribonucleotide reductase, barrel domain 243 311 3.7E-6 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS05930 09459d503c18a484e4d6bc16609e8cd8 669 Pfam PF02867 Ribonucleotide reductase, barrel domain 312 440 1.3E-18 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS27175 9044e03aacde3a92bbfbec0adaaa0f52 250 Gene3D G3DSA:3.30.1270.10 83 137 1.0E-39 T 06-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS27175 9044e03aacde3a92bbfbec0adaaa0f52 250 Gene3D G3DSA:3.30.1270.10 213 248 1.0E-39 T 06-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS27175 9044e03aacde3a92bbfbec0adaaa0f52 250 Gene3D G3DSA:1.10.10.200 1 78 5.8E-31 T 06-07-2017 IPR017856 Integrase, N-terminal zinc-binding domain-like SMD11_RS27175 9044e03aacde3a92bbfbec0adaaa0f52 250 Pfam PF01709 Transcriptional regulator 5 238 9.3E-88 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS27175 9044e03aacde3a92bbfbec0adaaa0f52 250 Gene3D G3DSA:3.30.70.980 138 205 1.1E-23 T 06-07-2017 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS27175 9044e03aacde3a92bbfbec0adaaa0f52 250 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 2.3E-97 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS27175 9044e03aacde3a92bbfbec0adaaa0f52 250 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.394 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS27175 9044e03aacde3a92bbfbec0adaaa0f52 250 SUPERFAMILY SSF75625 3 247 5.89E-89 T 06-07-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS34055 3167c0986aa16d13949c32460b080b18 360 Pfam PF00348 Polyprenyl synthetase 34 297 1.0E-56 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 SMD11_RS34055 3167c0986aa16d13949c32460b080b18 360 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 86 100 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 SMD11_RS34055 3167c0986aa16d13949c32460b080b18 360 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 238 250 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 SMD11_RS34055 3167c0986aa16d13949c32460b080b18 360 SUPERFAMILY SSF48576 27 359 1.01E-76 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS34055 3167c0986aa16d13949c32460b080b18 360 Gene3D G3DSA:1.10.600.10 7 359 6.0E-86 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS22130 a882d43ed9e496f217a130a1b837744b 360 SUPERFAMILY SSF82861 85 147 3.53E-9 T 06-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 SMD11_RS22130 a882d43ed9e496f217a130a1b837744b 360 Pfam PF00924 Mechanosensitive ion channel 107 306 1.6E-36 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SMD11_RS22130 a882d43ed9e496f217a130a1b837744b 360 SUPERFAMILY SSF50182 149 206 1.18E-9 T 06-07-2017 IPR010920 LSM domain SMD11_RS22130 a882d43ed9e496f217a130a1b837744b 360 Gene3D G3DSA:3.30.70.100 220 304 2.7E-7 T 06-07-2017 SMD11_RS22130 a882d43ed9e496f217a130a1b837744b 360 SUPERFAMILY SSF82689 213 306 4.97E-10 T 06-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 SMD11_RS22130 a882d43ed9e496f217a130a1b837744b 360 Gene3D G3DSA:2.30.30.60 164 208 2.0E-9 T 06-07-2017 SMD11_RS11265 4fcff1919182e218ddaa95d6077a81ab 261 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 17 246 1.8E-76 T 06-07-2017 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 SMD11_RS11265 4fcff1919182e218ddaa95d6077a81ab 261 SUPERFAMILY SSF100950 2 253 2.88E-87 T 06-07-2017 SMD11_RS11265 4fcff1919182e218ddaa95d6077a81ab 261 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 06-07-2017 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 SMD11_RS11265 4fcff1919182e218ddaa95d6077a81ab 261 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 242 39.191 T 06-07-2017 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 SMD11_RS11265 4fcff1919182e218ddaa95d6077a81ab 261 Gene3D G3DSA:3.40.50.1360 2 255 5.0E-90 T 06-07-2017 SMD11_RS11265 4fcff1919182e218ddaa95d6077a81ab 261 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 227 1.5E-23 T 06-07-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 SMD11_RS24590 dbe0b66ee0e083405e2403db4368a260 530 Pfam PF00999 Sodium/hydrogen exchanger family 9 405 2.0E-56 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMD11_RS24590 dbe0b66ee0e083405e2403db4368a260 530 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 9 525 8.3E-99 T 06-07-2017 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 SMD11_RS16150 7dd4ae9eb271e1bfee284e84b778b213 199 SUPERFAMILY SSF48498 81 191 8.22E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS16150 7dd4ae9eb271e1bfee284e84b778b213 199 SUPERFAMILY SSF46689 4 85 1.8E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS16150 7dd4ae9eb271e1bfee284e84b778b213 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS16150 7dd4ae9eb271e1bfee284e84b778b213 199 Gene3D G3DSA:1.10.357.10 5 188 6.1E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS25975 12235338dd6d880d6f90477bddfed4a2 645 Gene3D G3DSA:3.50.50.60 150 218 4.8E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS25975 12235338dd6d880d6f90477bddfed4a2 645 Gene3D G3DSA:3.50.50.60 32 87 4.8E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS25975 12235338dd6d880d6f90477bddfed4a2 645 Gene3D G3DSA:3.50.50.60 561 630 4.8E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS25975 12235338dd6d880d6f90477bddfed4a2 645 Pfam PF13454 FAD-NAD(P)-binding 34 215 1.1E-39 T 06-07-2017 SMD11_RS25975 12235338dd6d880d6f90477bddfed4a2 645 SUPERFAMILY SSF51905 144 222 9.97E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS25975 12235338dd6d880d6f90477bddfed4a2 645 SUPERFAMILY SSF51905 557 602 9.97E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS25975 12235338dd6d880d6f90477bddfed4a2 645 SUPERFAMILY SSF51905 33 78 9.97E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS17590 08937886fdfa5b52459a111d5d14c40f 758 Pfam PF02754 Cysteine-rich domain 478 580 1.0E-12 T 06-07-2017 IPR004017 Cysteine-rich domain SMD11_RS17590 08937886fdfa5b52459a111d5d14c40f 758 Pfam PF02754 Cysteine-rich domain 619 706 1.3E-19 T 06-07-2017 IPR004017 Cysteine-rich domain SMD11_RS17590 08937886fdfa5b52459a111d5d14c40f 758 Gene3D G3DSA:1.10.1060.10 279 422 4.6E-32 T 06-07-2017 SMD11_RS17590 08937886fdfa5b52459a111d5d14c40f 758 SUPERFAMILY SSF46548 285 338 7.32E-22 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 SMD11_RS17590 08937886fdfa5b52459a111d5d14c40f 758 SUPERFAMILY SSF46548 376 421 7.32E-22 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 SMD11_RS17590 08937886fdfa5b52459a111d5d14c40f 758 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 302 313 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD11_RS17590 08937886fdfa5b52459a111d5d14c40f 758 Pfam PF13183 4Fe-4S dicluster domain 299 407 2.6E-14 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD11_RS17590 08937886fdfa5b52459a111d5d14c40f 758 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 393 404 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SMD11_RS02755 67759f28f5c571ad5aa4d59a2a1d1116 168 Pfam PF01047 MarR family 56 111 3.4E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS02755 67759f28f5c571ad5aa4d59a2a1d1116 168 ProSitePatterns PS01117 MarR-type HTH domain signature. 85 119 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site SMD11_RS02755 67759f28f5c571ad5aa4d59a2a1d1116 168 Gene3D G3DSA:1.10.10.10 14 162 6.4E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02755 67759f28f5c571ad5aa4d59a2a1d1116 168 SUPERFAMILY SSF46785 23 157 2.91E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02755 67759f28f5c571ad5aa4d59a2a1d1116 168 SMART SM00347 45 146 2.6E-22 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS02755 67759f28f5c571ad5aa4d59a2a1d1116 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 1.1E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS02755 67759f28f5c571ad5aa4d59a2a1d1116 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 1.1E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS02755 67759f28f5c571ad5aa4d59a2a1d1116 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 1.1E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS02755 67759f28f5c571ad5aa4d59a2a1d1116 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 1.1E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS01330 0c11c4f08a7b8b2d957551a22930cc5c 321 Gene3D G3DSA:3.40.50.1820 42 296 6.5E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01330 0c11c4f08a7b8b2d957551a22930cc5c 321 SUPERFAMILY SSF53474 15 296 1.13E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS22990 5b8bf1c152b9e10810356c452e470b5c 331 PIRSF PIRSF026166 1 317 9.6E-105 T 06-07-2017 IPR016833 Putative sodium bile acid cotransporter SMD11_RS22990 5b8bf1c152b9e10810356c452e470b5c 331 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 2 303 7.7E-82 T 06-07-2017 IPR016833 Putative sodium bile acid cotransporter SMD11_RS17005 0ac27bc29122ceb02913a010934ba333 259 SUPERFAMILY SSF63817 104 246 3.01E-30 T 06-07-2017 IPR023365 Sortase domain SMD11_RS17005 0ac27bc29122ceb02913a010934ba333 259 TIGRFAM TIGR01076 sortase_fam: sortase 122 241 8.4E-13 T 06-07-2017 IPR005754 Sortase family SMD11_RS17005 0ac27bc29122ceb02913a010934ba333 259 Gene3D G3DSA:2.40.260.10 107 246 1.2E-25 T 06-07-2017 IPR023365 Sortase domain SMD11_RS17005 0ac27bc29122ceb02913a010934ba333 259 Pfam PF04203 Sortase family 112 243 1.5E-28 T 06-07-2017 IPR005754 Sortase family SMD11_RS11980 b32181d5de535e9def277118e2aad1d2 347 Gene3D G3DSA:3.40.50.300 4 257 1.8E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11980 b32181d5de535e9def277118e2aad1d2 347 Pfam PF00005 ABC transporter 33 183 2.1E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS11980 b32181d5de535e9def277118e2aad1d2 347 SMART SM00382 41 233 2.7E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS11980 b32181d5de535e9def277118e2aad1d2 347 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 329 2.2E-23 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS11980 b32181d5de535e9def277118e2aad1d2 347 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS11980 b32181d5de535e9def277118e2aad1d2 347 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 306 1.0E-14 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS11980 b32181d5de535e9def277118e2aad1d2 347 SUPERFAMILY SSF52540 7 254 7.5E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21660 36eb967805d4b56fca06391485aba93e 464 Pfam PF00232 Glycosyl hydrolase family 1 3 458 3.5E-146 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD11_RS21660 36eb967805d4b56fca06391485aba93e 464 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 06-07-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SMD11_RS21660 36eb967805d4b56fca06391485aba93e 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 287 301 1.1E-19 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD11_RS21660 36eb967805d4b56fca06391485aba93e 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 364 372 1.1E-19 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD11_RS21660 36eb967805d4b56fca06391485aba93e 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 385 396 1.1E-19 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD11_RS21660 36eb967805d4b56fca06391485aba93e 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 406 423 1.1E-19 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD11_RS21660 36eb967805d4b56fca06391485aba93e 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 430 442 1.1E-19 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SMD11_RS21660 36eb967805d4b56fca06391485aba93e 464 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 364 372 - T 06-07-2017 IPR018120 Glycoside hydrolase family 1, active site SMD11_RS21660 36eb967805d4b56fca06391485aba93e 464 TIGRFAM TIGR03356 BGL: beta-galactosidase 5 452 2.6E-171 T 06-07-2017 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 SMD11_RS21660 36eb967805d4b56fca06391485aba93e 464 Gene3D G3DSA:3.20.20.80 4 461 2.4E-152 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS21660 36eb967805d4b56fca06391485aba93e 464 SUPERFAMILY SSF51445 4 461 7.75E-154 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS14975 fd6569b7b8e3d433217e3c79f8698e51 505 Gene3D G3DSA:3.40.710.10 130 185 2.1E-6 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS14975 fd6569b7b8e3d433217e3c79f8698e51 505 Gene3D G3DSA:3.40.710.10 285 503 5.1E-60 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS14975 fd6569b7b8e3d433217e3c79f8698e51 505 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 118 274 2.2E-22 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD11_RS14975 fd6569b7b8e3d433217e3c79f8698e51 505 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 280 497 3.8E-48 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD11_RS14975 fd6569b7b8e3d433217e3c79f8698e51 505 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 283 480 1.3E-37 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD11_RS14975 fd6569b7b8e3d433217e3c79f8698e51 505 SUPERFAMILY SSF56601 123 503 5.5E-60 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS14975 fd6569b7b8e3d433217e3c79f8698e51 505 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 392 406 1.2E-17 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD11_RS14975 fd6569b7b8e3d433217e3c79f8698e51 505 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 457 470 1.2E-17 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD11_RS14975 fd6569b7b8e3d433217e3c79f8698e51 505 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 157 176 1.2E-17 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD11_RS14975 fd6569b7b8e3d433217e3c79f8698e51 505 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 377 391 1.2E-17 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD11_RS14975 fd6569b7b8e3d433217e3c79f8698e51 505 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 322 344 1.2E-17 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SMD11_RS26540 94bb3a036416f0d92d457b5d1993fae8 412 Pfam PF07690 Major Facilitator Superfamily 16 289 1.6E-11 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS26540 94bb3a036416f0d92d457b5d1993fae8 412 SUPERFAMILY SSF103473 8 382 4.05E-30 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS26540 94bb3a036416f0d92d457b5d1993fae8 412 Gene3D G3DSA:1.20.1250.20 26 192 7.0E-12 T 06-07-2017 SMD11_RS26540 94bb3a036416f0d92d457b5d1993fae8 412 Gene3D G3DSA:1.20.1250.20 202 384 3.3E-9 T 06-07-2017 SMD11_RS27245 03c6f2ccd10f1104015dd3f29341b358 456 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 65 169 2.6E-14 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS27245 03c6f2ccd10f1104015dd3f29341b358 456 SUPERFAMILY SSF52540 20 245 2.22E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27245 03c6f2ccd10f1104015dd3f29341b358 456 Gene3D G3DSA:3.40.50.300 11 170 2.7E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27245 03c6f2ccd10f1104015dd3f29341b358 456 Pfam PF12002 MgsA AAA+ ATPase C terminal 277 441 1.2E-67 T 06-07-2017 IPR021886 MgsA AAA+ ATPase C-terminal SMD11_RS27245 03c6f2ccd10f1104015dd3f29341b358 456 SUPERFAMILY SSF48019 262 444 5.95E-72 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 SMD11_RS27245 03c6f2ccd10f1104015dd3f29341b358 456 Gene3D G3DSA:1.20.272.10 258 356 2.5E-43 T 06-07-2017 SMD11_RS27245 03c6f2ccd10f1104015dd3f29341b358 456 SMART SM00382 61 182 4.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS27245 03c6f2ccd10f1104015dd3f29341b358 456 Pfam PF16193 AAA C-terminal domain 200 276 5.3E-25 T 06-07-2017 IPR032423 AAA ATPase, C-terminal domain SMD11_RS27245 03c6f2ccd10f1104015dd3f29341b358 456 Gene3D G3DSA:1.10.3710.10 357 446 4.7E-28 T 06-07-2017 SMD11_RS27245 03c6f2ccd10f1104015dd3f29341b358 456 Gene3D G3DSA:1.10.8.60 178 250 2.0E-7 T 06-07-2017 SMD11_RS29765 18420372598047171abade9393c7e549 437 Pfam PF00698 Acyl transferase domain 106 421 1.9E-57 T 06-07-2017 IPR014043 Acyl transferase SMD11_RS29765 18420372598047171abade9393c7e549 437 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 107 402 1.6E-121 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain SMD11_RS29765 18420372598047171abade9393c7e549 437 SUPERFAMILY SSF55048 230 294 5.75E-14 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SMD11_RS29765 18420372598047171abade9393c7e549 437 SUPERFAMILY SSF52151 295 388 3.4E-75 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS29765 18420372598047171abade9393c7e549 437 SUPERFAMILY SSF52151 103 231 3.4E-75 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS29765 18420372598047171abade9393c7e549 437 Gene3D G3DSA:3.30.70.250 230 293 5.1E-11 T 06-07-2017 SMD11_RS29765 18420372598047171abade9393c7e549 437 Gene3D G3DSA:3.40.366.10 294 407 1.2E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS29765 18420372598047171abade9393c7e549 437 Gene3D G3DSA:3.40.366.10 99 225 1.2E-79 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS11665 d80ac40b735e4f095348cf271e9a4588 571 Pfam PF11997 Domain of unknown function (DUF3492) 2 91 1.2E-13 T 06-07-2017 IPR022622 Domain of unknown function DUF3492 SMD11_RS11665 d80ac40b735e4f095348cf271e9a4588 571 Pfam PF11997 Domain of unknown function (DUF3492) 239 337 5.5E-10 T 06-07-2017 IPR022622 Domain of unknown function DUF3492 SMD11_RS11665 d80ac40b735e4f095348cf271e9a4588 571 Gene3D G3DSA:3.40.50.2000 378 508 1.7E-7 T 06-07-2017 SMD11_RS11665 d80ac40b735e4f095348cf271e9a4588 571 Pfam PF13692 Glycosyl transferases group 1 376 494 7.7E-13 T 06-07-2017 SMD11_RS11665 d80ac40b735e4f095348cf271e9a4588 571 SUPERFAMILY SSF53756 242 526 1.26E-40 T 06-07-2017 SMD11_RS11665 d80ac40b735e4f095348cf271e9a4588 571 SUPERFAMILY SSF53756 2 91 1.26E-40 T 06-07-2017 SMD11_RS20635 11329f6a9d95465b2a7562cedd83bb9d 583 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 156 312 1.1E-42 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS20635 11329f6a9d95465b2a7562cedd83bb9d 583 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 156 312 4.2E-45 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS20635 11329f6a9d95465b2a7562cedd83bb9d 583 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 423 514 1.1E-10 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMD11_RS06385 0b7203199738eda70ce5e5e049511cf6 660 SUPERFAMILY SSF82171 77 371 8.44E-17 T 06-07-2017 SMD11_RS06385 0b7203199738eda70ce5e5e049511cf6 660 Gene3D G3DSA:2.120.10.30 174 299 9.9E-14 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS06385 0b7203199738eda70ce5e5e049511cf6 660 Gene3D G3DSA:3.40.50.1820 352 642 6.3E-64 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS06385 0b7203199738eda70ce5e5e049511cf6 660 Pfam PF00326 Prolyl oligopeptidase family 443 647 8.9E-45 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMD11_RS06385 0b7203199738eda70ce5e5e049511cf6 660 SUPERFAMILY SSF53474 389 644 1.42E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS26795 aacff9972d8d854bad4f4d3b9283380d 740 PIRSF PIRSF009407 1 740 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SMD11_RS26795 aacff9972d8d854bad4f4d3b9283380d 740 Gene3D G3DSA:3.40.718.10 338 361 1.4E-33 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMD11_RS26795 aacff9972d8d854bad4f4d3b9283380d 740 Gene3D G3DSA:3.40.718.10 537 644 1.4E-33 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMD11_RS26795 aacff9972d8d854bad4f4d3b9283380d 740 Gene3D G3DSA:3.40.718.10 171 284 1.4E-33 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMD11_RS26795 aacff9972d8d854bad4f4d3b9283380d 740 Pfam PF03971 Monomeric isocitrate dehydrogenase 5 736 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SMD11_RS26795 aacff9972d8d854bad4f4d3b9283380d 740 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 3 739 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SMD11_RS26795 aacff9972d8d854bad4f4d3b9283380d 740 SUPERFAMILY SSF53659 4 739 0.0 T 06-07-2017 SMD11_RS16190 0f6ff7919779f464809cb2b23604a2d1 282 Gene3D G3DSA:3.20.20.80 49 276 2.8E-58 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS16190 0f6ff7919779f464809cb2b23604a2d1 282 Pfam PF08924 Domain of unknown function (DUF1906) 62 198 4.7E-33 T 06-07-2017 IPR015020 Protein of unknown function DUF1906 SMD11_RS16190 0f6ff7919779f464809cb2b23604a2d1 282 SUPERFAMILY SSF51445 49 275 1.26E-34 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS00330 37a0ae0258930356918f00fd55ea6008 156 Pfam PF12680 SnoaL-like domain 33 145 3.6E-10 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain SMD11_RS00330 37a0ae0258930356918f00fd55ea6008 156 SUPERFAMILY SSF54427 19 152 2.1E-21 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS00330 37a0ae0258930356918f00fd55ea6008 156 Gene3D G3DSA:3.10.450.50 12 152 5.0E-35 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS04910 62ba4a682ea041dd6d1791e5d442b526 532 Gene3D G3DSA:3.50.50.60 464 525 3.3E-89 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS04910 62ba4a682ea041dd6d1791e5d442b526 532 Gene3D G3DSA:3.50.50.60 204 329 3.3E-89 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS04910 62ba4a682ea041dd6d1791e5d442b526 532 Gene3D G3DSA:3.50.50.60 21 140 3.3E-89 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS04910 62ba4a682ea041dd6d1791e5d442b526 532 SUPERFAMILY SSF54373 351 471 5.69E-21 T 06-07-2017 SMD11_RS04910 62ba4a682ea041dd6d1791e5d442b526 532 Pfam PF05199 GMC oxidoreductase 384 522 3.6E-36 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS04910 62ba4a682ea041dd6d1791e5d442b526 532 SUPERFAMILY SSF51905 21 304 4.05E-70 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS04910 62ba4a682ea041dd6d1791e5d442b526 532 SUPERFAMILY SSF51905 470 526 4.05E-70 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS04910 62ba4a682ea041dd6d1791e5d442b526 532 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 270 284 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS04910 62ba4a682ea041dd6d1791e5d442b526 532 Pfam PF00732 GMC oxidoreductase 21 310 1.1E-65 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS04910 62ba4a682ea041dd6d1791e5d442b526 532 PIRSF PIRSF000137 16 526 2.6E-108 T 06-07-2017 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 SMD11_RS14070 dcbfba6d532f1a17662f1a9cd1947e10 256 SUPERFAMILY SSF141571 70 243 2.26E-39 T 06-07-2017 SMD11_RS14070 dcbfba6d532f1a17662f1a9cd1947e10 256 Pfam PF13599 Pentapeptide repeats (9 copies) 162 212 6.1E-9 T 06-07-2017 IPR001646 Pentapeptide repeat SMD11_RS14070 dcbfba6d532f1a17662f1a9cd1947e10 256 Pfam PF13599 Pentapeptide repeats (9 copies) 84 158 6.9E-9 T 06-07-2017 IPR001646 Pentapeptide repeat SMD11_RS13620 59e709d526ea2de4be2595fc9f102567 387 SUPERFAMILY SSF56645 7 243 1.01E-58 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS13620 59e709d526ea2de4be2595fc9f102567 387 SUPERFAMILY SSF47203 229 385 4.51E-39 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS13620 59e709d526ea2de4be2595fc9f102567 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 4.1E-26 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS13620 59e709d526ea2de4be2595fc9f102567 387 Gene3D G3DSA:1.20.140.10 222 386 4.2E-45 T 06-07-2017 SMD11_RS13620 59e709d526ea2de4be2595fc9f102567 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 376 3.7E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS13620 59e709d526ea2de4be2595fc9f102567 387 Gene3D G3DSA:1.10.540.10 8 119 4.2E-29 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS13620 59e709d526ea2de4be2595fc9f102567 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 217 3.6E-17 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS13620 59e709d526ea2de4be2595fc9f102567 387 Gene3D G3DSA:2.40.110.10 122 221 3.2E-25 T 06-07-2017 SMD11_RS18335 05f18690653742472d28d4c3163b7e5a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.9E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS18335 05f18690653742472d28d4c3163b7e5a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.9E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS18335 05f18690653742472d28d4c3163b7e5a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.9E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS18335 05f18690653742472d28d4c3163b7e5a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.9E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS18335 05f18690653742472d28d4c3163b7e5a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.9E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS18335 05f18690653742472d28d4c3163b7e5a 255 Pfam PF00106 short chain dehydrogenase 5 190 5.1E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS18335 05f18690653742472d28d4c3163b7e5a 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 189 4.4E-4 T 06-07-2017 SMD11_RS18335 05f18690653742472d28d4c3163b7e5a 255 Gene3D G3DSA:3.40.50.720 2 240 1.6E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18335 05f18690653742472d28d4c3163b7e5a 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS18335 05f18690653742472d28d4c3163b7e5a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 6.3E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS18335 05f18690653742472d28d4c3163b7e5a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 6.3E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS18335 05f18690653742472d28d4c3163b7e5a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 6.3E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS18335 05f18690653742472d28d4c3163b7e5a 255 SUPERFAMILY SSF51735 2 243 7.92E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05360 a558c2f9ed56d1efa7b415c50bead800 296 Gene3D G3DSA:3.90.550.10 6 229 3.9E-26 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS05360 a558c2f9ed56d1efa7b415c50bead800 296 SUPERFAMILY SSF53448 5 225 3.19E-35 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS05360 a558c2f9ed56d1efa7b415c50bead800 296 Pfam PF00535 Glycosyl transferase family 2 6 164 3.4E-10 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD11_RS31910 f454afecda0d3622af6a2b676be1080a 436 Gene3D G3DSA:3.40.50.1820 161 432 4.4E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS31910 f454afecda0d3622af6a2b676be1080a 436 Pfam PF00756 Putative esterase 194 427 3.0E-17 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 SMD11_RS31910 f454afecda0d3622af6a2b676be1080a 436 SUPERFAMILY SSF53474 193 430 1.41E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS26595 188fe0cbc697c442d259f3a103531932 941 SMART SM00490 354 446 3.8E-12 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS26595 188fe0cbc697c442d259f3a103531932 941 Pfam PF00271 Helicase conserved C-terminal domain 367 446 6.1E-5 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS26595 188fe0cbc697c442d259f3a103531932 941 Pfam PF08148 DSHCT (NUC185) domain 766 935 1.1E-36 T 06-07-2017 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal SMD11_RS26595 188fe0cbc697c442d259f3a103531932 941 SMART SM01142 763 940 9.2E-64 T 06-07-2017 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal SMD11_RS26595 188fe0cbc697c442d259f3a103531932 941 Gene3D G3DSA:3.40.50.300 33 216 1.5E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26595 188fe0cbc697c442d259f3a103531932 941 Pfam PF00270 DEAD/DEAH box helicase 38 186 3.3E-18 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD11_RS26595 188fe0cbc697c442d259f3a103531932 941 SMART SM00487 32 214 4.3E-30 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS26595 188fe0cbc697c442d259f3a103531932 941 Pfam PF13234 rRNA-processing arch domain 502 739 4.8E-6 T 06-07-2017 IPR025696 rRNA-processing arch domain SMD11_RS26595 188fe0cbc697c442d259f3a103531932 941 Gene3D G3DSA:3.40.50.300 295 327 2.5E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26595 188fe0cbc697c442d259f3a103531932 941 Gene3D G3DSA:3.40.50.300 369 456 2.5E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26595 188fe0cbc697c442d259f3a103531932 941 SUPERFAMILY SSF52540 46 187 3.17E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26595 188fe0cbc697c442d259f3a103531932 941 SUPERFAMILY SSF52540 366 458 3.17E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26595 188fe0cbc697c442d259f3a103531932 941 SUPERFAMILY SSF52540 268 324 3.17E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21730 2571e151a44943743549c0a48462a5d1 312 Pfam PF00682 HMGL-like 17 288 7.9E-48 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMD11_RS21730 2571e151a44943743549c0a48462a5d1 312 SUPERFAMILY SSF51569 14 306 2.05E-69 T 06-07-2017 SMD11_RS21730 2571e151a44943743549c0a48462a5d1 312 Gene3D G3DSA:3.20.20.70 16 302 3.5E-82 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS22740 bb1836d5ec40ecec1bd070fbc8368917 119 Pfam PF01230 HIT domain 17 112 1.4E-23 T 06-07-2017 IPR001310 Histidine triad (HIT) protein SMD11_RS22740 bb1836d5ec40ecec1bd070fbc8368917 119 PRINTS PR00332 Histidine triad family signature 10 26 6.9E-19 T 06-07-2017 IPR001310 Histidine triad (HIT) protein SMD11_RS22740 bb1836d5ec40ecec1bd070fbc8368917 119 PRINTS PR00332 Histidine triad family signature 99 109 6.9E-19 T 06-07-2017 IPR001310 Histidine triad (HIT) protein SMD11_RS22740 bb1836d5ec40ecec1bd070fbc8368917 119 PRINTS PR00332 Histidine triad family signature 31 49 6.9E-19 T 06-07-2017 IPR001310 Histidine triad (HIT) protein SMD11_RS22740 bb1836d5ec40ecec1bd070fbc8368917 119 SUPERFAMILY SSF54197 7 118 1.11E-33 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 SMD11_RS22740 bb1836d5ec40ecec1bd070fbc8368917 119 Gene3D G3DSA:3.30.428.10 4 119 1.1E-37 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 SMD11_RS15155 d9d2014efaf5741a7f6aa5514521cf5d 242 Pfam PF01872 RibD C-terminal domain 19 231 8.1E-39 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD11_RS15155 d9d2014efaf5741a7f6aa5514521cf5d 242 SUPERFAMILY SSF53597 18 236 1.64E-45 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD11_RS15155 d9d2014efaf5741a7f6aa5514521cf5d 242 Gene3D G3DSA:3.40.430.10 10 235 4.0E-55 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD11_RS26040 d78130ac595279404c3113da53fcd748 165 Gene3D G3DSA:2.40.380.10 7 155 9.1E-39 T 06-07-2017 IPR007295 Domain of unknown function DUF402 SMD11_RS26040 d78130ac595279404c3113da53fcd748 165 Pfam PF04167 Protein of unknown function (DUF402) 61 128 2.2E-19 T 06-07-2017 IPR007295 Domain of unknown function DUF402 SMD11_RS26040 d78130ac595279404c3113da53fcd748 165 SUPERFAMILY SSF159234 54 153 1.31E-15 T 06-07-2017 SMD11_RS22085 17fa98374b93d1a548ab4ed05d1abedd 273 ProSitePatterns PS00498 Tyrosinase and hemocyanins CuB-binding region signature. 209 220 - T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS22085 17fa98374b93d1a548ab4ed05d1abedd 273 ProSitePatterns PS00497 Tyrosinase CuA-binding region signature. 54 71 - T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS22085 17fa98374b93d1a548ab4ed05d1abedd 273 Pfam PF00264 Common central domain of tyrosinase 30 228 5.5E-45 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS22085 17fa98374b93d1a548ab4ed05d1abedd 273 Gene3D G3DSA:1.10.1280.10 1 272 1.2E-66 T 06-07-2017 IPR008922 Uncharacterised domain, di-copper centre SMD11_RS22085 17fa98374b93d1a548ab4ed05d1abedd 273 SUPERFAMILY SSF48056 1 272 9.48E-67 T 06-07-2017 IPR008922 Uncharacterised domain, di-copper centre SMD11_RS22085 17fa98374b93d1a548ab4ed05d1abedd 273 PRINTS PR00092 Tyrosinase copper-binding domain signature 54 71 2.8E-19 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS22085 17fa98374b93d1a548ab4ed05d1abedd 273 PRINTS PR00092 Tyrosinase copper-binding domain signature 83 88 2.8E-19 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS22085 17fa98374b93d1a548ab4ed05d1abedd 273 PRINTS PR00092 Tyrosinase copper-binding domain signature 208 226 2.8E-19 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS22085 17fa98374b93d1a548ab4ed05d1abedd 273 PRINTS PR00092 Tyrosinase copper-binding domain signature 189 200 2.8E-19 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS02055 7fe8738e35e8c7e092f4892876ef518a 270 SUPERFAMILY SSF110710 8 264 2.62E-88 T 06-07-2017 SMD11_RS02055 7fe8738e35e8c7e092f4892876ef518a 270 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 32 260 3.1E-77 T 06-07-2017 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 SMD11_RS22310 f9c5752da50b99247186b50ea3799029 224 PRINTS PR00127 Clp protease catalytic subunit P signature 193 212 3.6E-41 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS22310 f9c5752da50b99247186b50ea3799029 224 PRINTS PR00127 Clp protease catalytic subunit P signature 43 58 3.6E-41 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS22310 f9c5752da50b99247186b50ea3799029 224 PRINTS PR00127 Clp protease catalytic subunit P signature 114 131 3.6E-41 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS22310 f9c5752da50b99247186b50ea3799029 224 PRINTS PR00127 Clp protease catalytic subunit P signature 83 103 3.6E-41 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS22310 f9c5752da50b99247186b50ea3799029 224 PRINTS PR00127 Clp protease catalytic subunit P signature 135 154 3.6E-41 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS22310 f9c5752da50b99247186b50ea3799029 224 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 136 149 - T 06-07-2017 IPR033135 ClpP, histidine active site SMD11_RS22310 f9c5752da50b99247186b50ea3799029 224 Gene3D G3DSA:3.90.226.10 28 218 1.1E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS22310 f9c5752da50b99247186b50ea3799029 224 Pfam PF00574 Clp protease 37 217 8.6E-75 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SMD11_RS22310 f9c5752da50b99247186b50ea3799029 224 SUPERFAMILY SSF52096 35 219 5.8E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS22310 f9c5752da50b99247186b50ea3799029 224 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 114 125 - T 06-07-2017 IPR018215 ClpP, Ser active site SMD11_RS22310 f9c5752da50b99247186b50ea3799029 224 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 27 218 38.953 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS21315 f51b9f2650d6cd858d82c17af69ee77f 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.2E-27 T 06-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 SMD11_RS21315 f51b9f2650d6cd858d82c17af69ee77f 106 SUPERFAMILY SSF103481 6 104 9.94E-17 T 06-07-2017 SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 1.3E-28 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 1.3E-28 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 1.3E-28 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 1.3E-28 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 1.3E-28 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 SUPERFAMILY SSF50447 461 561 1.87E-17 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 SUPERFAMILY SSF55681 2 248 1.16E-91 T 06-07-2017 SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 Gene3D G3DSA:3.30.930.10 1 244 7.0E-97 T 06-07-2017 SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 SUPERFAMILY SSF55186 561 720 1.28E-42 T 06-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 SMART SM00863 662 705 4.5E-21 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 Pfam PF02272 DHHA1 domain 813 882 1.2E-11 T 06-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 868 4.8E-259 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 Pfam PF01411 tRNA synthetases class II (A) 5 563 1.5E-194 T 06-07-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 SUPERFAMILY SSF101353 249 446 1.7E-60 T 06-07-2017 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 662 705 1.7E-17 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SMD11_RS27275 d08b0c2bc517009bf745b9f77738966d 889 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 889 170.499 T 06-07-2017 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 SMD11_RS21100 ea704d289418d44a9d3c356fd381ce58 184 Gene3D G3DSA:2.60.120.10 54 173 1.7E-34 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS21100 ea704d289418d44a9d3c356fd381ce58 184 Pfam PF05995 Cysteine dioxygenase type I 63 162 9.9E-11 T 06-07-2017 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 SMD11_RS21100 ea704d289418d44a9d3c356fd381ce58 184 SUPERFAMILY SSF51182 10 178 1.54E-42 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS00575 d02aaa18622dc514f2de537e9ce0ead4 379 Gene3D G3DSA:1.10.540.10 37 95 7.7E-9 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS00575 d02aaa18622dc514f2de537e9ce0ead4 379 SUPERFAMILY SSF47203 245 372 1.74E-6 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS00575 d02aaa18622dc514f2de537e9ce0ead4 379 SUPERFAMILY SSF56645 8 225 7.98E-30 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS00575 d02aaa18622dc514f2de537e9ce0ead4 379 Gene3D G3DSA:1.20.140.10 218 354 2.5E-4 T 06-07-2017 SMD11_RS00575 d02aaa18622dc514f2de537e9ce0ead4 379 Gene3D G3DSA:2.40.110.10 132 217 1.3E-15 T 06-07-2017 SMD11_RS19335 c9c2b89a7e111a35381a098d89c5116a 306 Gene3D G3DSA:3.40.50.720 4 258 6.8E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19335 c9c2b89a7e111a35381a098d89c5116a 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19335 c9c2b89a7e111a35381a098d89c5116a 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19335 c9c2b89a7e111a35381a098d89c5116a 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19335 c9c2b89a7e111a35381a098d89c5116a 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19335 c9c2b89a7e111a35381a098d89c5116a 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 1.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19335 c9c2b89a7e111a35381a098d89c5116a 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19335 c9c2b89a7e111a35381a098d89c5116a 306 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 198 1.3E-5 T 06-07-2017 SMD11_RS19335 c9c2b89a7e111a35381a098d89c5116a 306 SUPERFAMILY SSF51735 5 249 2.9E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19335 c9c2b89a7e111a35381a098d89c5116a 306 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 242 2.6E-37 T 06-07-2017 SMD11_RS02610 74a67e9878902f5cd9323d365aa008b6 182 SUPERFAMILY SSF56235 1 161 1.87E-13 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS02870 a0905267445957b0942f7d02a7031f33 468 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 261 272 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS02870 a0905267445957b0942f7d02a7031f33 468 Gene3D G3DSA:3.40.309.10 248 434 1.4E-66 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS02870 a0905267445957b0942f7d02a7031f33 468 Gene3D G3DSA:3.40.605.10 3 247 8.2E-72 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS02870 a0905267445957b0942f7d02a7031f33 468 SUPERFAMILY SSF53720 3 462 4.71E-146 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS02870 a0905267445957b0942f7d02a7031f33 468 Pfam PF00171 Aldehyde dehydrogenase family 3 459 8.2E-143 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS08625 b6a51b1570b935df096e54c39abc237b 269 SUPERFAMILY SSF46785 26 91 3.86E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08625 b6a51b1570b935df096e54c39abc237b 269 Gene3D G3DSA:1.10.10.10 25 88 2.1E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08625 b6a51b1570b935df096e54c39abc237b 269 Gene3D G3DSA:1.20.120.530 90 220 2.5E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS08625 b6a51b1570b935df096e54c39abc237b 269 SMART SM00895 97 219 6.5E-17 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS08625 b6a51b1570b935df096e54c39abc237b 269 Pfam PF07729 FCD domain 97 215 1.6E-20 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS08625 b6a51b1570b935df096e54c39abc237b 269 SMART SM00345 29 87 1.4E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS08625 b6a51b1570b935df096e54c39abc237b 269 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 87 5.1E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS08625 b6a51b1570b935df096e54c39abc237b 269 SUPERFAMILY SSF48008 93 219 7.32E-19 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS08625 b6a51b1570b935df096e54c39abc237b 269 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 61 2.1E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS08625 b6a51b1570b935df096e54c39abc237b 269 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 77 2.1E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS14035 0587c0b387c0a457b571fd0e87707702 67 Pfam PF14013 MT0933-like antitoxin protein 4 52 1.4E-15 T 06-07-2017 IPR028037 Antitoxin Rv0909/MT0933 SMD11_RS17730 94ab8f8ef6a76ca7ef332ff1eee7ab45 270 Gene3D G3DSA:2.70.98.10 28 200 4.8E-14 T 06-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 SMD11_RS17730 94ab8f8ef6a76ca7ef332ff1eee7ab45 270 Pfam PF01263 Aldose 1-epimerase 27 189 3.5E-19 T 06-07-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 SMD11_RS17730 94ab8f8ef6a76ca7ef332ff1eee7ab45 270 SUPERFAMILY SSF74650 8 247 8.16E-38 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SMD11_RS10990 47bfd46c12d69444293bf5a032bf01cc 152 Gene3D G3DSA:1.10.150.120 76 151 2.4E-30 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD11_RS10990 47bfd46c12d69444293bf5a032bf01cc 152 SUPERFAMILY SSF47741 85 151 3.79E-28 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD11_RS10990 47bfd46c12d69444293bf5a032bf01cc 152 Pfam PF01799 [2Fe-2S] binding domain 74 144 7.9E-26 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD11_RS10990 47bfd46c12d69444293bf5a032bf01cc 152 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 58 4.6E-6 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS10990 47bfd46c12d69444293bf5a032bf01cc 152 Gene3D G3DSA:3.10.20.30 5 75 5.2E-23 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS10990 47bfd46c12d69444293bf5a032bf01cc 152 SUPERFAMILY SSF54292 4 88 7.01E-24 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS13425 861bef7f7b439f3597fe04c475c3e8e3 172 Pfam PF04978 Protein of unknown function (DUF664) 21 168 1.4E-40 T 06-07-2017 IPR007061 Protein of unknown function DUF664 SMD11_RS13425 861bef7f7b439f3597fe04c475c3e8e3 172 Gene3D G3DSA:1.20.120.450 3 171 1.2E-43 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase SMD11_RS13425 861bef7f7b439f3597fe04c475c3e8e3 172 SUPERFAMILY SSF109854 4 167 4.73E-43 T 06-07-2017 SMD11_RS25985 5e4c6ce7fd057427a140ff1aae94b255 448 SUPERFAMILY SSF51679 11 438 3.4E-107 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS25985 5e4c6ce7fd057427a140ff1aae94b255 448 PIRSF PIRSF000337 8 447 3.2E-143 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMD11_RS25985 5e4c6ce7fd057427a140ff1aae94b255 448 Gene3D G3DSA:3.20.20.30 11 305 1.1E-115 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS25985 5e4c6ce7fd057427a140ff1aae94b255 448 Gene3D G3DSA:3.20.20.30 355 438 1.1E-115 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS25985 5e4c6ce7fd057427a140ff1aae94b255 448 Pfam PF00296 Luciferase-like monooxygenase 32 384 1.3E-52 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS25985 5e4c6ce7fd057427a140ff1aae94b255 448 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 22 434 4.0E-126 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 SMD11_RS31540 28017bd8c6b9f4c4d51c104c06530e7d 213 Pfam PF13649 Methyltransferase domain 10 106 8.6E-21 T 06-07-2017 SMD11_RS31540 28017bd8c6b9f4c4d51c104c06530e7d 213 Gene3D G3DSA:3.40.50.150 6 180 1.2E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS31540 28017bd8c6b9f4c4d51c104c06530e7d 213 SUPERFAMILY SSF53335 2 187 5.78E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS33295 b088d1af8ddf10cb49879d276d5f6ee0 707 SUPERFAMILY SSF54665 9 141 9.16E-35 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS33295 b088d1af8ddf10cb49879d276d5f6ee0 707 Gene3D G3DSA:3.30.365.10 127 174 1.7E-6 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS33295 b088d1af8ddf10cb49879d276d5f6ee0 707 Gene3D G3DSA:3.30.365.10 281 305 1.7E-6 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS33295 b088d1af8ddf10cb49879d276d5f6ee0 707 SMART SM01008 26 138 1.1E-33 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS33295 b088d1af8ddf10cb49879d276d5f6ee0 707 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 26 138 6.2E-19 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS33295 b088d1af8ddf10cb49879d276d5f6ee0 707 Gene3D G3DSA:3.30.365.10 446 570 6.1E-22 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS33295 b088d1af8ddf10cb49879d276d5f6ee0 707 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 161 644 4.7E-107 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS33295 b088d1af8ddf10cb49879d276d5f6ee0 707 SUPERFAMILY SSF56003 134 702 1.57E-154 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS33295 b088d1af8ddf10cb49879d276d5f6ee0 707 Gene3D G3DSA:3.30.365.10 175 277 4.0E-35 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS33295 b088d1af8ddf10cb49879d276d5f6ee0 707 Gene3D G3DSA:3.90.1170.50 5 126 2.5E-33 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMD11_RS33295 b088d1af8ddf10cb49879d276d5f6ee0 707 Gene3D G3DSA:3.30.365.10 571 702 5.7E-55 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS33295 b088d1af8ddf10cb49879d276d5f6ee0 707 Gene3D G3DSA:3.30.365.10 354 443 5.7E-55 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 SMD11_RS19030 6a7ac190308e01ad042e1730733ecf2e 154 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS19030 6a7ac190308e01ad042e1730733ecf2e 154 SUPERFAMILY SSF64263 1 118 4.06E-47 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS19030 6a7ac190308e01ad042e1730733ecf2e 154 Gene3D G3DSA:3.90.1030.10 4 117 1.3E-46 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS19030 6a7ac190308e01ad042e1730733ecf2e 154 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 117 9.8E-42 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS19030 6a7ac190308e01ad042e1730733ecf2e 154 Pfam PF01196 Ribosomal protein L17 20 116 8.0E-38 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS19030 6a7ac190308e01ad042e1730733ecf2e 154 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.092 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS21235 71fea257b9aa048178e58241627f4b0b 250 SUPERFAMILY SSF56281 1 250 6.22E-54 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS21235 71fea257b9aa048178e58241627f4b0b 250 Pfam PF12706 Beta-lactamase superfamily domain 30 218 4.0E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS21235 71fea257b9aa048178e58241627f4b0b 250 SMART SM00849 18 199 2.9E-4 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS21235 71fea257b9aa048178e58241627f4b0b 250 Gene3D G3DSA:3.60.15.10 1 249 8.1E-60 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS23115 8b997792427515fba423576b77d1cb6d 142 Gene3D G3DSA:3.30.300.20 50 141 3.3E-37 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta SMD11_RS23115 8b997792427515fba423576b77d1cb6d 142 Gene3D G3DSA:2.20.25.10 7 49 1.3E-19 T 06-07-2017 SMD11_RS23115 8b997792427515fba423576b77d1cb6d 142 Pfam PF02566 OsmC-like protein 43 139 5.3E-18 T 06-07-2017 IPR003718 OsmC/Ohr family SMD11_RS23115 8b997792427515fba423576b77d1cb6d 142 SUPERFAMILY SSF82784 3 141 5.23E-43 T 06-07-2017 IPR003718 OsmC/Ohr family SMD11_RS23115 8b997792427515fba423576b77d1cb6d 142 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 9 141 5.3E-56 T 06-07-2017 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 SMD11_RS26875 8b8a120d8bbf71dd2a3d055525c30792 465 Pfam PF13347 MFS/sugar transport protein 36 451 1.1E-72 T 06-07-2017 SMD11_RS26875 8b8a120d8bbf71dd2a3d055525c30792 465 SUPERFAMILY SSF103473 34 446 9.68E-27 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS26875 8b8a120d8bbf71dd2a3d055525c30792 465 Gene3D G3DSA:1.20.1250.20 256 446 1.9E-9 T 06-07-2017 SMD11_RS26875 8b8a120d8bbf71dd2a3d055525c30792 465 Gene3D G3DSA:1.20.1250.20 34 218 3.9E-10 T 06-07-2017 SMD11_RS33875 94f34794b07dcd458a62e4864dfcac56 305 SUPERFAMILY SSF56601 47 300 8.05E-73 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS33875 94f34794b07dcd458a62e4864dfcac56 305 Gene3D G3DSA:3.40.710.10 47 303 8.9E-100 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS33875 94f34794b07dcd458a62e4864dfcac56 305 Pfam PF13354 Beta-lactamase enzyme family 67 277 6.9E-42 T 06-07-2017 SMD11_RS33875 94f34794b07dcd458a62e4864dfcac56 305 PRINTS PR00118 Beta-lactamase class A signature 47 71 1.0E-61 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD11_RS33875 94f34794b07dcd458a62e4864dfcac56 305 PRINTS PR00118 Beta-lactamase class A signature 220 235 1.0E-61 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD11_RS33875 94f34794b07dcd458a62e4864dfcac56 305 PRINTS PR00118 Beta-lactamase class A signature 122 147 1.0E-61 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD11_RS33875 94f34794b07dcd458a62e4864dfcac56 305 PRINTS PR00118 Beta-lactamase class A signature 237 252 1.0E-61 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD11_RS33875 94f34794b07dcd458a62e4864dfcac56 305 PRINTS PR00118 Beta-lactamase class A signature 78 95 1.0E-61 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD11_RS33875 94f34794b07dcd458a62e4864dfcac56 305 PRINTS PR00118 Beta-lactamase class A signature 184 209 1.0E-61 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD11_RS33875 94f34794b07dcd458a62e4864dfcac56 305 PRINTS PR00118 Beta-lactamase class A signature 158 182 1.0E-61 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD11_RS33875 94f34794b07dcd458a62e4864dfcac56 305 ProSitePatterns PS00146 Beta-lactamase class-A active site. 80 95 - T 06-07-2017 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 SMD11_RS18535 5fe5fd3cc0ebd03235e88585d29a668f 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 19 118 1.6E-36 T 06-07-2017 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18535 5fe5fd3cc0ebd03235e88585d29a668f 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 119 17.786 T 06-07-2017 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 SMD11_RS29710 274ed201a48e7940ff4244d7b156f913 505 SUPERFAMILY SSF103473 469 491 3.79E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS29710 274ed201a48e7940ff4244d7b156f913 505 SUPERFAMILY SSF103473 259 430 3.79E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS29710 274ed201a48e7940ff4244d7b156f913 505 SUPERFAMILY SSF103473 6 207 3.79E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS29710 274ed201a48e7940ff4244d7b156f913 505 Gene3D G3DSA:1.20.1250.20 277 473 3.2E-12 T 06-07-2017 SMD11_RS29710 274ed201a48e7940ff4244d7b156f913 505 Pfam PF07690 Major Facilitator Superfamily 27 420 1.5E-46 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS29710 274ed201a48e7940ff4244d7b156f913 505 Gene3D G3DSA:1.20.1250.20 20 203 1.9E-26 T 06-07-2017 SMD11_RS19850 091e3e622591559d20880fd5ee4f40cb 300 Pfam PF00483 Nucleotidyl transferase 10 273 6.9E-27 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMD11_RS19850 091e3e622591559d20880fd5ee4f40cb 300 SUPERFAMILY SSF53448 10 291 5.18E-64 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS19850 091e3e622591559d20880fd5ee4f40cb 300 Gene3D G3DSA:3.90.550.10 10 282 1.4E-75 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS19850 091e3e622591559d20880fd5ee4f40cb 300 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 273 1.5E-101 T 06-07-2017 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 SMD11_RS20015 f3398e925dae4704dbc0cd2a3249b258 353 Pfam PF13190 PDGLE domain 254 330 2.5E-15 T 06-07-2017 IPR025937 PDGLE domain SMD11_RS20015 f3398e925dae4704dbc0cd2a3249b258 353 ProDom PD486863 PRECURSOR CBIM SIGNAL COBALT MEMBRANE VITAMIN B12 BIOSYNTHESIS COBALAMIN ABC-TYPE 263 310 1.0E-11 T 06-07-2017 SMD11_RS20015 f3398e925dae4704dbc0cd2a3249b258 353 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 208 6.3E-59 T 06-07-2017 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 SMD11_RS29380 888a4f1b4dd95a12db2071aaf46841fe 616 SUPERFAMILY SSF47336 7 99 6.94E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29380 888a4f1b4dd95a12db2071aaf46841fe 616 Gene3D G3DSA:1.10.1200.10 5 86 7.9E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29380 888a4f1b4dd95a12db2071aaf46841fe 616 ProSitePatterns PS00455 Putative AMP-binding domain signature. 271 282 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS29380 888a4f1b4dd95a12db2071aaf46841fe 616 SUPERFAMILY SSF56801 109 613 3.01E-111 T 06-07-2017 SMD11_RS29380 888a4f1b4dd95a12db2071aaf46841fe 616 Gene3D G3DSA:3.30.300.30 512 612 3.8E-24 T 06-07-2017 SMD11_RS29380 888a4f1b4dd95a12db2071aaf46841fe 616 Gene3D G3DSA:3.40.50.980 256 281 6.9E-24 T 06-07-2017 SMD11_RS29380 888a4f1b4dd95a12db2071aaf46841fe 616 Gene3D G3DSA:3.40.50.980 122 224 6.9E-24 T 06-07-2017 SMD11_RS29380 888a4f1b4dd95a12db2071aaf46841fe 616 Pfam PF00501 AMP-binding enzyme 121 517 1.9E-71 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS29380 888a4f1b4dd95a12db2071aaf46841fe 616 Gene3D G3DSA:3.40.50.980 282 430 8.1E-32 T 06-07-2017 SMD11_RS29380 888a4f1b4dd95a12db2071aaf46841fe 616 Pfam PF00550 Phosphopantetheine attachment site 13 80 2.1E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29380 888a4f1b4dd95a12db2071aaf46841fe 616 Gene3D G3DSA:2.30.38.10 438 510 1.6E-15 T 06-07-2017 SMD11_RS29380 888a4f1b4dd95a12db2071aaf46841fe 616 Pfam PF13193 AMP-binding enzyme C-terminal domain 526 603 5.8E-15 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS21815 c6426ed5d42cda0c5bdf530b2bd256ea 385 SUPERFAMILY SSF51569 50 335 1.36E-13 T 06-07-2017 SMD11_RS21815 c6426ed5d42cda0c5bdf530b2bd256ea 385 Pfam PF06187 Protein of unknown function (DUF993) 2 383 3.4E-171 T 06-07-2017 IPR009334 Protein of unknown function DUF993 SMD11_RS21815 c6426ed5d42cda0c5bdf530b2bd256ea 385 Gene3D G3DSA:3.20.20.70 55 331 2.0E-7 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS23135 4fb3d84f0fbdeb9bb7144e77a77ca8b2 263 Pfam PF02308 MgtC family 26 156 2.7E-36 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SMD11_RS23135 4fb3d84f0fbdeb9bb7144e77a77ca8b2 263 PRINTS PR01837 MgtC/SapB protein signature 48 66 2.1E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SMD11_RS23135 4fb3d84f0fbdeb9bb7144e77a77ca8b2 263 PRINTS PR01837 MgtC/SapB protein signature 29 48 2.1E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SMD11_RS23135 4fb3d84f0fbdeb9bb7144e77a77ca8b2 263 PRINTS PR01837 MgtC/SapB protein signature 111 135 2.1E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SMD11_RS23135 4fb3d84f0fbdeb9bb7144e77a77ca8b2 263 PRINTS PR01837 MgtC/SapB protein signature 84 106 2.1E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SMD11_RS16665 f69212e8203e39f3043ba40c59232b3c 210 SUPERFAMILY SSF56784 3 189 2.84E-18 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS16665 f69212e8203e39f3043ba40c59232b3c 210 Gene3D G3DSA:3.40.50.1000 64 192 1.6E-14 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS16665 f69212e8203e39f3043ba40c59232b3c 210 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 170 4.1E-14 T 06-07-2017 SMD11_RS28010 7194c889de6ae84fb1e9cb2a375bf91e 214 SMART SM00895 77 200 7.3E-12 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS28010 7194c889de6ae84fb1e9cb2a375bf91e 214 SUPERFAMILY SSF46785 4 71 1.11E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28010 7194c889de6ae84fb1e9cb2a375bf91e 214 Pfam PF07729 FCD domain 77 195 5.0E-17 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS28010 7194c889de6ae84fb1e9cb2a375bf91e 214 Gene3D G3DSA:1.10.10.10 5 68 5.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28010 7194c889de6ae84fb1e9cb2a375bf91e 214 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 6.8E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS28010 7194c889de6ae84fb1e9cb2a375bf91e 214 SMART SM00345 9 67 1.7E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS28010 7194c889de6ae84fb1e9cb2a375bf91e 214 Gene3D G3DSA:1.20.120.530 72 211 2.1E-31 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS28010 7194c889de6ae84fb1e9cb2a375bf91e 214 SUPERFAMILY SSF48008 73 209 8.37E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS07620 19dc9607ad020663f349fe472d48821b 509 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 79 496 1.5E-43 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD11_RS07620 19dc9607ad020663f349fe472d48821b 509 SMART SM00530 12 67 3.1E-14 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS07620 19dc9607ad020663f349fe472d48821b 509 Gene3D G3DSA:3.65.10.10 293 504 2.2E-40 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD11_RS07620 19dc9607ad020663f349fe472d48821b 509 Gene3D G3DSA:3.65.10.10 92 292 1.3E-39 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD11_RS07620 19dc9607ad020663f349fe472d48821b 509 SUPERFAMILY SSF47413 5 65 1.66E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS07620 19dc9607ad020663f349fe472d48821b 509 Gene3D G3DSA:1.10.260.40 6 66 1.4E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS07620 19dc9607ad020663f349fe472d48821b 509 Pfam PF01381 Helix-turn-helix 13 63 7.0E-14 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS07620 19dc9607ad020663f349fe472d48821b 509 SUPERFAMILY SSF55205 74 506 2.29E-96 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SMD11_RS30065 3326cb7de4b1c77f8a9bead4dea21958 170 Pfam PF00583 Acetyltransferase (GNAT) family 62 134 2.2E-9 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS30065 3326cb7de4b1c77f8a9bead4dea21958 170 SUPERFAMILY SSF55729 4 139 1.72E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS30065 3326cb7de4b1c77f8a9bead4dea21958 170 Gene3D G3DSA:3.40.630.30 1 145 4.5E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS20325 536016d8c407a39c14ad10db94611b85 839 Pfam PF12704 MacB-like periplasmic core domain 17 236 4.2E-19 T 06-07-2017 IPR025857 MacB-like periplasmic core domain SMD11_RS20325 536016d8c407a39c14ad10db94611b85 839 Pfam PF12704 MacB-like periplasmic core domain 486 681 4.2E-12 T 06-07-2017 IPR025857 MacB-like periplasmic core domain SMD11_RS20325 536016d8c407a39c14ad10db94611b85 839 Pfam PF02687 FtsX-like permease family 271 392 1.5E-23 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 SMD11_RS20325 536016d8c407a39c14ad10db94611b85 839 Pfam PF02687 FtsX-like permease family 715 831 2.4E-22 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 SMD11_RS25835 102624284134d869bc451480a3f50eb4 441 SMART SM00363 205 266 2.4E-9 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 SMD11_RS25835 102624284134d869bc451480a3f50eb4 441 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 270 428 2.4E-43 T 06-07-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 SMD11_RS25835 102624284134d869bc451480a3f50eb4 441 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 303 317 - T 06-07-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 SMD11_RS25835 102624284134d869bc451480a3f50eb4 441 Pfam PF01479 S4 domain 205 251 5.7E-12 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 SMD11_RS25835 102624284134d869bc451480a3f50eb4 441 Gene3D G3DSA:3.10.290.10 203 263 6.5E-22 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 SMD11_RS25835 102624284134d869bc451480a3f50eb4 441 Pfam PF00849 RNA pseudouridylate synthase 267 397 1.0E-21 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS25835 102624284134d869bc451480a3f50eb4 441 SUPERFAMILY SSF55174 201 269 4.91E-12 T 06-07-2017 SMD11_RS25835 102624284134d869bc451480a3f50eb4 441 SUPERFAMILY SSF55120 250 439 1.42E-43 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS24210 cea69404b162fe2dbc3727b83b027f42 133 Gene3D G3DSA:3.40.50.2300 4 129 3.9E-11 T 06-07-2017 SMD11_RS24210 cea69404b162fe2dbc3727b83b027f42 133 SUPERFAMILY SSF52172 6 130 1.71E-9 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS26035 179ac461859ee4a23fcc024f8c6ef188 306 SUPERFAMILY SSF48576 14 190 1.27E-16 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS26035 179ac461859ee4a23fcc024f8c6ef188 306 Gene3D G3DSA:1.10.600.10 11 146 4.9E-23 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS21690 74820990a303f595f67dc69b7b929b71 459 Gene3D G3DSA:3.40.50.880 24 238 2.3E-47 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS21690 74820990a303f595f67dc69b7b929b71 459 Gene3D G3DSA:1.10.10.60 284 333 3.9E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS21690 74820990a303f595f67dc69b7b929b71 459 Pfam PF12833 Helix-turn-helix domain 253 331 7.5E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS21690 74820990a303f595f67dc69b7b929b71 459 SUPERFAMILY SSF52317 24 212 1.99E-45 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS21690 74820990a303f595f67dc69b7b929b71 459 Gene3D G3DSA:1.10.10.60 239 283 2.3E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS21690 74820990a303f595f67dc69b7b929b71 459 Pfam PF01965 DJ-1/PfpI family 60 191 2.9E-14 T 06-07-2017 IPR002818 DJ-1/PfpI SMD11_RS21690 74820990a303f595f67dc69b7b929b71 459 SMART SM00342 247 330 2.3E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS21690 74820990a303f595f67dc69b7b929b71 459 SUPERFAMILY SSF46689 232 280 5.73E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS21690 74820990a303f595f67dc69b7b929b71 459 SUPERFAMILY SSF46689 284 334 1.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS33135 c53ff5bedfeab8ce6d99d8714e225f6d 141 Pfam PF06841 T4-like virus tail tube protein gp19 9 138 1.5E-29 T 06-07-2017 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 SMD11_RS33135 c53ff5bedfeab8ce6d99d8714e225f6d 141 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 7 139 1.3E-23 T 06-07-2017 IPR011747 Conserved hypothetical protein CHP02241 SMD11_RS03085 40c657fce57145d4f66586e607311d3e 325 Gene3D G3DSA:1.10.10.10 2 79 3.4E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03085 40c657fce57145d4f66586e607311d3e 325 SUPERFAMILY SSF46894 256 325 4.76E-13 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS03085 40c657fce57145d4f66586e607311d3e 325 Gene3D G3DSA:1.10.10.10 262 325 7.9E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03085 40c657fce57145d4f66586e607311d3e 325 Pfam PF00196 Bacterial regulatory proteins, luxR family 264 315 3.1E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS03085 40c657fce57145d4f66586e607311d3e 325 SMART SM00421 262 319 1.5E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS34075 2983c5d2c3c94505df184d935255f237 434 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 126 405 9.9E-89 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 SMD11_RS34075 2983c5d2c3c94505df184d935255f237 434 Pfam PF02401 LytB protein 126 405 5.8E-85 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 SMD11_RS34075 2983c5d2c3c94505df184d935255f237 434 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 124 409 36.41 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 SMD11_RS16530 4d192469c68df4a9424ef2921621b21a 301 Gene3D G3DSA:3.20.20.30 18 292 2.1E-55 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS16530 4d192469c68df4a9424ef2921621b21a 301 Pfam PF00296 Luciferase-like monooxygenase 20 235 2.4E-41 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS16530 4d192469c68df4a9424ef2921621b21a 301 SUPERFAMILY SSF51679 18 277 2.75E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS14850 f4f38655dc394df98af1c9fd88346bd7 289 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 20 281 3.9E-80 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 SMD11_RS14850 f4f38655dc394df98af1c9fd88346bd7 289 Gene3D G3DSA:3.30.1300.10 177 286 2.7E-31 T 06-07-2017 SMD11_RS14850 f4f38655dc394df98af1c9fd88346bd7 289 Gene3D G3DSA:3.40.50.620 6 176 9.2E-71 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS14850 f4f38655dc394df98af1c9fd88346bd7 289 SUPERFAMILY SSF52374 10 284 2.57E-91 T 06-07-2017 SMD11_RS14850 f4f38655dc394df98af1c9fd88346bd7 289 Pfam PF02569 Pantoate-beta-alanine ligase 10 281 2.1E-90 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 SMD11_RS14850 f4f38655dc394df98af1c9fd88346bd7 289 Hamap MF_00158 Pantothenate synthetase [panC]. 4 283 37.896 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 SMD11_RS27370 0097d554e8ba2dbcda812937cec391f1 372 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 302 322 - T 06-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 SMD11_RS27370 0097d554e8ba2dbcda812937cec391f1 372 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 4 367 2.0E-128 T 06-07-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD11_RS27370 0097d554e8ba2dbcda812937cec391f1 372 Pfam PF01180 Dihydroorotate dehydrogenase 50 350 5.7E-96 T 06-07-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 SMD11_RS27370 0097d554e8ba2dbcda812937cec391f1 372 SUPERFAMILY SSF51395 1 364 3.66E-104 T 06-07-2017 SMD11_RS27370 0097d554e8ba2dbcda812937cec391f1 372 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 346 47.2 T 06-07-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD11_RS27370 0097d554e8ba2dbcda812937cec391f1 372 Gene3D G3DSA:3.20.20.70 1 366 2.7E-130 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS17255 69ca7e2dc9ab25288a0fef4b9d7351eb 281 SMART SM00530 22 95 4.0E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS17255 69ca7e2dc9ab25288a0fef4b9d7351eb 281 Gene3D G3DSA:1.10.260.40 16 94 6.0E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS17255 69ca7e2dc9ab25288a0fef4b9d7351eb 281 Pfam PF13560 Helix-turn-helix domain 19 97 3.1E-14 T 06-07-2017 SMD11_RS17255 69ca7e2dc9ab25288a0fef4b9d7351eb 281 SUPERFAMILY SSF47413 45 92 1.1E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS22605 1b6a3ab89eea32be0053436048b31ea3 410 SMART SM00729 29 259 2.3E-61 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD11_RS22605 1b6a3ab89eea32be0053436048b31ea3 410 SUPERFAMILY SSF102114 20 408 3.79E-109 T 06-07-2017 SMD11_RS22605 1b6a3ab89eea32be0053436048b31ea3 410 Pfam PF04055 Radical SAM superfamily 35 212 1.3E-22 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS22605 1b6a3ab89eea32be0053436048b31ea3 410 Gene3D G3DSA:3.80.30.20 32 274 4.9E-36 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe SMD11_RS22605 1b6a3ab89eea32be0053436048b31ea3 410 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 32 364 3.7E-72 T 06-07-2017 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 SMD11_RS14220 b6a4f45f749919e42a67217f9ddf1c4c 268 SUPERFAMILY SSF53335 27 193 1.21E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS14220 b6a4f45f749919e42a67217f9ddf1c4c 268 Gene3D G3DSA:3.40.50.150 38 149 8.7E-6 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS30600 1a3d0a8cfd7fa1c49ef66a8df6191f6e 416 Gene3D G3DSA:1.20.1250.20 9 184 1.6E-6 T 06-07-2017 SMD11_RS30600 1a3d0a8cfd7fa1c49ef66a8df6191f6e 416 SUPERFAMILY SSF103473 9 400 7.32E-37 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS30600 1a3d0a8cfd7fa1c49ef66a8df6191f6e 416 Pfam PF07690 Major Facilitator Superfamily 15 328 3.3E-21 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS30600 1a3d0a8cfd7fa1c49ef66a8df6191f6e 416 Gene3D G3DSA:1.20.1250.20 226 409 1.9E-17 T 06-07-2017 SMD11_RS15855 e321916d0ecb75a425119552743bc78f 207 PIRSF PIRSF006324 1 207 5.1E-46 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 SMD11_RS15855 e321916d0ecb75a425119552743bc78f 207 Pfam PF01810 LysE type translocator 17 205 7.8E-31 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 SMD11_RS27560 f340c380287859ab5f8870254cd8439e 278 SUPERFAMILY SSF53335 16 251 2.41E-44 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS27560 f340c380287859ab5f8870254cd8439e 278 Gene3D G3DSA:3.40.50.150 3 278 2.7E-109 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS27560 f340c380287859ab5f8870254cd8439e 278 PIRSF PIRSF017393 2 278 1.9E-96 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD11_RS27560 f340c380287859ab5f8870254cd8439e 278 Pfam PF04672 S-adenosyl methyltransferase 5 277 2.0E-96 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD11_RS07265 8a44eac3b5153a6d2792722b2e446bf5 298 SUPERFAMILY SSF55486 61 278 1.97E-18 T 06-07-2017 SMD11_RS07265 8a44eac3b5153a6d2792722b2e446bf5 298 Gene3D G3DSA:3.40.390.10 156 217 4.9E-8 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD11_RS07265 8a44eac3b5153a6d2792722b2e446bf5 298 Pfam PF05572 Pregnancy-associated plasma protein-A 139 282 2.6E-13 T 06-07-2017 IPR008754 Peptidase M43, pregnancy-associated plasma-A Reactome: R-HSA-381426 SMD11_RS18480 3302223739dfea00543f649aa57f4dcb 67 SMART SM00357 3 67 2.6E-31 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 SMD11_RS18480 3302223739dfea00543f649aa57f4dcb 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site SMD11_RS18480 3302223739dfea00543f649aa57f4dcb 67 PIRSF PIRSF002599 1 67 4.3E-26 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 SMD11_RS18480 3302223739dfea00543f649aa57f4dcb 67 PRINTS PR00050 Cold shock protein signature 25 34 4.9E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS18480 3302223739dfea00543f649aa57f4dcb 67 PRINTS PR00050 Cold shock protein signature 4 19 4.9E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS18480 3302223739dfea00543f649aa57f4dcb 67 PRINTS PR00050 Cold shock protein signature 40 58 4.9E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS18480 3302223739dfea00543f649aa57f4dcb 67 SUPERFAMILY SSF50249 1 66 6.0E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS18480 3302223739dfea00543f649aa57f4dcb 67 Gene3D G3DSA:2.40.50.140 1 65 4.0E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS18480 3302223739dfea00543f649aa57f4dcb 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.2E-31 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS04615 9136ca41973f2b59df14eaf017661a0a 366 Pfam PF00487 Fatty acid desaturase 67 316 1.7E-31 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 SMD11_RS15510 0947864b251ee8db317e386f4b389aea 276 Pfam PF00753 Metallo-beta-lactamase superfamily 36 194 8.4E-14 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS15510 0947864b251ee8db317e386f4b389aea 276 SUPERFAMILY SSF56281 26 275 4.2E-47 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS15510 0947864b251ee8db317e386f4b389aea 276 SMART SM00849 39 204 3.8E-23 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS15510 0947864b251ee8db317e386f4b389aea 276 Gene3D G3DSA:3.60.15.10 23 234 4.6E-45 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS13435 9bcf1c5cf5cb0808a83899827435b2ea 98 SUPERFAMILY SSF51182 1 96 9.93E-15 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS13435 9bcf1c5cf5cb0808a83899827435b2ea 98 Gene3D G3DSA:2.60.120.10 1 97 2.1E-17 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS13435 9bcf1c5cf5cb0808a83899827435b2ea 98 Pfam PF07883 Cupin domain 36 86 6.7E-12 T 06-07-2017 IPR013096 Cupin 2, conserved barrel SMD11_RS29165 6fd18987da7f8769fd5bbed74f332ab2 490 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 302 488 6.6E-44 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS29165 6fd18987da7f8769fd5bbed74f332ab2 490 Gene3D G3DSA:3.30.450.20 116 216 4.2E-13 T 06-07-2017 SMD11_RS29165 6fd18987da7f8769fd5bbed74f332ab2 490 Pfam PF08447 PAS fold 126 208 8.1E-10 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 SMD11_RS29165 6fd18987da7f8769fd5bbed74f332ab2 490 SMART SM00086 176 218 4.1E-4 T 06-07-2017 IPR001610 PAC motif SMD11_RS29165 6fd18987da7f8769fd5bbed74f332ab2 490 SUPERFAMILY SSF81606 357 488 2.62E-5 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS29165 6fd18987da7f8769fd5bbed74f332ab2 490 SMART SM00331 276 488 9.3E-21 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS29165 6fd18987da7f8769fd5bbed74f332ab2 490 SUPERFAMILY SSF55785 117 216 3.84E-12 T 06-07-2017 IPR000014 PAS domain SMD11_RS20995 76fbf06dec1cebb7b4a3313cefda2a36 795 Pfam PF13538 UvrD-like helicase C-terminal domain 735 776 6.6E-8 T 06-07-2017 IPR027785 UvrD-like helicase C-terminal domain SMD11_RS20995 76fbf06dec1cebb7b4a3313cefda2a36 795 Gene3D G3DSA:3.40.50.300 639 780 7.9E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20995 76fbf06dec1cebb7b4a3313cefda2a36 795 Gene3D G3DSA:3.40.50.300 452 615 7.6E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20995 76fbf06dec1cebb7b4a3313cefda2a36 795 Gene3D G3DSA:3.40.50.300 220 288 7.6E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20995 76fbf06dec1cebb7b4a3313cefda2a36 795 Pfam PF00580 UvrD/REP helicase N-terminal domain 565 613 2.0E-5 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 SMD11_RS20995 76fbf06dec1cebb7b4a3313cefda2a36 795 SUPERFAMILY SSF52540 214 292 1.67E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20995 76fbf06dec1cebb7b4a3313cefda2a36 795 SUPERFAMILY SSF52540 406 459 1.67E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20995 76fbf06dec1cebb7b4a3313cefda2a36 795 SUPERFAMILY SSF52540 559 781 1.67E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20995 76fbf06dec1cebb7b4a3313cefda2a36 795 Pfam PF13245 Part of AAA domain 228 284 7.3E-13 T 06-07-2017 SMD11_RS32375 da7ebd2dcfadc06dada5de9e68a97ba4 192 Pfam PF00196 Bacterial regulatory proteins, luxR family 116 170 6.4E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS32375 da7ebd2dcfadc06dada5de9e68a97ba4 192 SMART SM00421 114 171 3.6E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS32375 da7ebd2dcfadc06dada5de9e68a97ba4 192 SUPERFAMILY SSF46894 108 177 1.77E-11 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS32375 da7ebd2dcfadc06dada5de9e68a97ba4 192 Pfam PF08448 PAS fold 3 89 1.1E-7 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS32375 da7ebd2dcfadc06dada5de9e68a97ba4 192 Gene3D G3DSA:3.30.450.20 2 87 2.6E-9 T 06-07-2017 SMD11_RS32375 da7ebd2dcfadc06dada5de9e68a97ba4 192 Gene3D G3DSA:1.10.10.10 112 176 3.9E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32375 da7ebd2dcfadc06dada5de9e68a97ba4 192 SUPERFAMILY SSF55785 3 62 1.4E-8 T 06-07-2017 IPR000014 PAS domain SMD11_RS30775 6fa3ba0dc026e175042906349587024c 313 Gene3D G3DSA:3.40.50.720 8 302 5.4E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30775 6fa3ba0dc026e175042906349587024c 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 206 2.3E-11 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 SMD11_RS30775 6fa3ba0dc026e175042906349587024c 313 SUPERFAMILY SSF51735 10 308 7.59E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29495 c35ebd3cd17b73d76691986a24be765a 173 SUPERFAMILY SSF55729 11 172 2.74E-28 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS29495 c35ebd3cd17b73d76691986a24be765a 173 Pfam PF13420 Acetyltransferase (GNAT) domain 20 167 3.2E-21 T 06-07-2017 SMD11_RS29495 c35ebd3cd17b73d76691986a24be765a 173 Gene3D G3DSA:3.40.630.30 8 172 3.9E-37 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS33510 26ff850d1c2d7ae2e468a5d017f54888 296 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 44 261 3.4E-35 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase SMD11_RS33510 26ff850d1c2d7ae2e468a5d017f54888 296 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 22 294 3.8E-115 T 06-07-2017 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 SMD11_RS33510 26ff850d1c2d7ae2e468a5d017f54888 296 SUPERFAMILY SSF51197 33 292 7.42E-58 T 06-07-2017 SMD11_RS33510 26ff850d1c2d7ae2e468a5d017f54888 296 Gene3D G3DSA:2.60.120.620 25 275 1.8E-50 T 06-07-2017 SMD11_RS07350 f05d603dd8b68fdbc58798281ecac40d 265 Gene3D G3DSA:3.40.430.10 47 263 3.7E-56 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD11_RS07350 f05d603dd8b68fdbc58798281ecac40d 265 SUPERFAMILY SSF53597 48 262 4.32E-37 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD11_RS07350 f05d603dd8b68fdbc58798281ecac40d 265 Pfam PF01872 RibD C-terminal domain 48 241 7.7E-27 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD11_RS13050 d6fb241746fd6c4435dea4363bdb15e6 561 SUPERFAMILY SSF55545 114 209 3.53E-13 T 06-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS13050 d6fb241746fd6c4435dea4363bdb15e6 561 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 214 541 2.4E-39 T 06-07-2017 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 SMD11_RS13050 d6fb241746fd6c4435dea4363bdb15e6 561 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 95 208 1.2E-12 T 06-07-2017 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 SMD11_RS13050 d6fb241746fd6c4435dea4363bdb15e6 561 Gene3D G3DSA:3.20.20.80 198 553 5.5E-72 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS13050 d6fb241746fd6c4435dea4363bdb15e6 561 Gene3D G3DSA:3.30.379.10 84 197 2.1E-13 T 06-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS13050 d6fb241746fd6c4435dea4363bdb15e6 561 PRINTS PR00738 Glycosyl hydrolase family 20 signature 346 359 6.1E-17 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS13050 d6fb241746fd6c4435dea4363bdb15e6 561 PRINTS PR00738 Glycosyl hydrolase family 20 signature 504 520 6.1E-17 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS13050 d6fb241746fd6c4435dea4363bdb15e6 561 PRINTS PR00738 Glycosyl hydrolase family 20 signature 282 299 6.1E-17 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS13050 d6fb241746fd6c4435dea4363bdb15e6 561 PRINTS PR00738 Glycosyl hydrolase family 20 signature 173 193 6.1E-17 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS13050 d6fb241746fd6c4435dea4363bdb15e6 561 PRINTS PR00738 Glycosyl hydrolase family 20 signature 205 222 6.1E-17 T 06-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 SMD11_RS13050 d6fb241746fd6c4435dea4363bdb15e6 561 SUPERFAMILY SSF51445 213 553 4.91E-74 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS28350 b4f18e749e0cec6e5cad1b10d1bb960e 333 PIRSF PIRSF006493 1 293 4.4E-83 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type SMD11_RS28350 b4f18e749e0cec6e5cad1b10d1bb960e 333 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 172 1.2E-28 T 06-07-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 SMD11_RS28350 b4f18e749e0cec6e5cad1b10d1bb960e 333 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 254 3.5E-83 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type SMD11_RS28350 b4f18e749e0cec6e5cad1b10d1bb960e 333 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 253 31.1 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type SMD11_RS28350 b4f18e749e0cec6e5cad1b10d1bb960e 333 SUPERFAMILY SSF100939 1 257 7.65E-46 T 06-07-2017 IPR016194 SPOC-like, C-terminal domain SMD11_RS28350 b4f18e749e0cec6e5cad1b10d1bb960e 333 SMART SM00559 52 181 1.0E-24 T 06-07-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 SMD11_RS21125 ceed01497e18544f80c655d1bfcb1530 268 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 158 251 7.0E-6 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 SMD11_RS21125 ceed01497e18544f80c655d1bfcb1530 268 Gene3D G3DSA:3.30.230.10 111 253 4.9E-22 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SMD11_RS21125 ceed01497e18544f80c655d1bfcb1530 268 SUPERFAMILY SSF54211 111 254 2.09E-18 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold SMD11_RS10860 9c12cefd17ccf900127b096bcb5f05ce 371 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 109 265 7.6E-54 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS10860 9c12cefd17ccf900127b096bcb5f05ce 371 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 109 265 1.7E-48 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS16555 21d3321a081e5e03e6b8d18d2debec3c 339 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 2 210 5.3E-74 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SMD11_RS16555 21d3321a081e5e03e6b8d18d2debec3c 339 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 320 2.2E-113 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SMD11_RS16555 21d3321a081e5e03e6b8d18d2debec3c 339 PIRSF PIRSF000267 1 334 2.1E-122 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SMD11_RS17875 eb310429335008e5c614ab5ab1dc6500 544 SUPERFAMILY SSF55874 293 411 1.48E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS17875 eb310429335008e5c614ab5ab1dc6500 544 Pfam PF07730 Histidine kinase 212 279 5.2E-14 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS32620 43881bbc3f89997aa990560e3fb0cea7 425 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 243 280 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS32620 43881bbc3f89997aa990560e3fb0cea7 425 Pfam PF00202 Aminotransferase class-III 22 420 6.5E-113 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS32620 43881bbc3f89997aa990560e3fb0cea7 425 Gene3D G3DSA:3.90.1150.10 1 61 8.5E-48 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS32620 43881bbc3f89997aa990560e3fb0cea7 425 Gene3D G3DSA:3.90.1150.10 333 423 8.5E-48 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS32620 43881bbc3f89997aa990560e3fb0cea7 425 SUPERFAMILY SSF53383 3 422 1.99E-117 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS32620 43881bbc3f89997aa990560e3fb0cea7 425 Gene3D G3DSA:3.40.640.10 62 330 7.5E-88 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS32620 43881bbc3f89997aa990560e3fb0cea7 425 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 9 422 1.6E-161 T 06-07-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 SMD11_RS26315 be1aacb39248c9e30c4af3116b7d4acb 447 Pfam PF07687 Peptidase dimerisation domain 207 335 1.5E-14 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS26315 be1aacb39248c9e30c4af3116b7d4acb 447 SUPERFAMILY SSF55031 210 255 2.88E-9 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS26315 be1aacb39248c9e30c4af3116b7d4acb 447 SUPERFAMILY SSF55031 296 336 2.88E-9 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS26315 be1aacb39248c9e30c4af3116b7d4acb 447 Gene3D G3DSA:3.30.70.360 297 342 9.0E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS26315 be1aacb39248c9e30c4af3116b7d4acb 447 Gene3D G3DSA:3.30.70.360 220 259 9.0E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS26315 be1aacb39248c9e30c4af3116b7d4acb 447 SUPERFAMILY SSF53187 20 210 1.26E-54 T 06-07-2017 SMD11_RS26315 be1aacb39248c9e30c4af3116b7d4acb 447 SUPERFAMILY SSF53187 357 445 1.26E-54 T 06-07-2017 SMD11_RS26315 be1aacb39248c9e30c4af3116b7d4acb 447 Pfam PF01546 Peptidase family M20/M25/M40 90 445 1.2E-37 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD11_RS26315 be1aacb39248c9e30c4af3116b7d4acb 447 Gene3D G3DSA:3.40.630.10 19 219 5.3E-61 T 06-07-2017 SMD11_RS26315 be1aacb39248c9e30c4af3116b7d4acb 447 Gene3D G3DSA:3.40.630.10 382 446 5.3E-61 T 06-07-2017 SMD11_RS26315 be1aacb39248c9e30c4af3116b7d4acb 447 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 89 98 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SMD11_RS14455 2a5e676dd8fd073aabf8e096fefdb254 141 Gene3D G3DSA:3.50.80.10 1 140 3.1E-53 T 06-07-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain SMD11_RS14455 2a5e676dd8fd073aabf8e096fefdb254 141 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 141 1.9E-41 T 06-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 SMD11_RS14455 2a5e676dd8fd073aabf8e096fefdb254 141 SUPERFAMILY SSF69500 1 140 8.24E-47 T 06-07-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain SMD11_RS14455 2a5e676dd8fd073aabf8e096fefdb254 141 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 140 8.7E-50 T 06-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 SMD11_RS14455 2a5e676dd8fd073aabf8e096fefdb254 141 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 141 31.019 T 06-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 SMD11_RS27595 ffdfed4110b8c2d1965b8c61d3879729 210 Gene3D G3DSA:3.40.50.1000 54 157 3.6E-8 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS27595 ffdfed4110b8c2d1965b8c61d3879729 210 SUPERFAMILY SSF56784 53 157 4.48E-8 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS31965 c6c262b162e22151c979613f71cc2a29 140 Pfam PF01638 HxlR-like helix-turn-helix 36 121 2.9E-26 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type SMD11_RS31965 c6c262b162e22151c979613f71cc2a29 140 Gene3D G3DSA:1.10.10.10 22 133 6.2E-42 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS31965 c6c262b162e22151c979613f71cc2a29 140 SUPERFAMILY SSF46785 25 128 2.16E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02540 7826bc23be9d4f834cb55e2472486d88 171 Gene3D G3DSA:2.30.110.10 21 170 1.3E-40 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS02540 7826bc23be9d4f834cb55e2472486d88 171 SUPERFAMILY SSF50475 23 157 1.8E-25 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS02540 7826bc23be9d4f834cb55e2472486d88 171 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 27 108 4.2E-14 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD11_RS06705 d75bb2316e736afff190531b4a3d11fa 76 Gene3D G3DSA:3.90.820.10 10 67 7.0E-31 T 06-07-2017 SMD11_RS06705 d75bb2316e736afff190531b4a3d11fa 76 Pfam PF03621 MbtH-like protein 1 53 6.8E-28 T 06-07-2017 IPR005153 MbtH-like protein SMD11_RS06705 d75bb2316e736afff190531b4a3d11fa 76 SMART SM00923 3 53 2.7E-29 T 06-07-2017 IPR005153 MbtH-like protein SMD11_RS06705 d75bb2316e736afff190531b4a3d11fa 76 SUPERFAMILY SSF160582 1 68 7.59E-31 T 06-07-2017 SMD11_RS13275 02e5e677ab379af2c8063d3b558393d3 137 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 7 133 1.3E-48 T 06-07-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 SMD11_RS13275 02e5e677ab379af2c8063d3b558393d3 137 SUPERFAMILY SSF52242 5 134 1.7E-49 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD11_RS13275 02e5e677ab379af2c8063d3b558393d3 137 Gene3D G3DSA:3.40.50.280 6 132 5.9E-55 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD11_RS13275 02e5e677ab379af2c8063d3b558393d3 137 Pfam PF02310 B12 binding domain 7 120 4.1E-24 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 SMD11_RS29300 a240795e78640f4f2957b96c8ea4d814 157 Gene3D G3DSA:3.90.1720.10 38 155 3.2E-38 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS29300 a240795e78640f4f2957b96c8ea4d814 157 SUPERFAMILY SSF54001 43 155 9.81E-36 T 06-07-2017 SMD11_RS29300 a240795e78640f4f2957b96c8ea4d814 157 Pfam PF00877 NlpC/P60 family 56 146 9.9E-24 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS30655 bfda9652b2130de678063e1f14e873ce 388 SUPERFAMILY SSF56601 20 242 1.46E-70 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS30655 bfda9652b2130de678063e1f14e873ce 388 SUPERFAMILY SSF56601 271 370 1.46E-70 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS30655 bfda9652b2130de678063e1f14e873ce 388 Pfam PF00144 Beta-lactamase 43 358 9.4E-60 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS30655 bfda9652b2130de678063e1f14e873ce 388 Gene3D G3DSA:3.40.710.10 51 375 1.3E-71 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS13895 214041273dd79cc381dc9daee81e7b93 314 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 199 216 - T 06-07-2017 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 SMD11_RS13895 214041273dd79cc381dc9daee81e7b93 314 SUPERFAMILY SSF53697 20 261 2.63E-64 T 06-07-2017 SMD11_RS13895 214041273dd79cc381dc9daee81e7b93 314 Pfam PF01380 SIS domain 143 222 5.0E-10 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 SMD11_RS13895 214041273dd79cc381dc9daee81e7b93 314 Gene3D G3DSA:3.40.50.10490 17 263 1.7E-79 T 06-07-2017 SMD11_RS13895 214041273dd79cc381dc9daee81e7b93 314 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 16 309 41.672 T 06-07-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 SMD11_RS13895 214041273dd79cc381dc9daee81e7b93 314 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 20 309 7.5E-111 T 06-07-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 SMD11_RS30410 2e7434e01efef589880e68292af3258d 418 Pfam PF09017 Microbial transglutaminase 1 418 4.1E-258 T 06-07-2017 IPR015107 Protein-glutamine gamma-glutamyltransferase GO:0003810 SMD11_RS30410 2e7434e01efef589880e68292af3258d 418 Gene3D G3DSA:3.90.1360.10 89 418 1.6E-204 T 06-07-2017 IPR015107 Protein-glutamine gamma-glutamyltransferase GO:0003810 SMD11_RS30410 2e7434e01efef589880e68292af3258d 418 SUPERFAMILY SSF54001 89 418 2.55E-198 T 06-07-2017 SMD11_RS30410 2e7434e01efef589880e68292af3258d 418 PIRSF PIRSF037210 1 418 9.3E-258 T 06-07-2017 IPR015107 Protein-glutamine gamma-glutamyltransferase GO:0003810 SMD11_RS15280 a6d41d9589f424bc392225031d18d289 509 Pfam PF05175 Methyltransferase small domain 170 287 3.4E-14 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 SMD11_RS15280 a6d41d9589f424bc392225031d18d289 509 Gene3D G3DSA:3.40.50.150 168 303 2.6E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS15280 a6d41d9589f424bc392225031d18d289 509 SUPERFAMILY SSF53335 168 301 2.09E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS15280 a6d41d9589f424bc392225031d18d289 509 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 237 243 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SMD11_RS24040 e4dfe2f98532c3258ae9f0ceb3abc818 483 Gene3D G3DSA:1.25.40.10 370 437 2.2E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS24040 e4dfe2f98532c3258ae9f0ceb3abc818 483 Gene3D G3DSA:1.25.40.10 266 314 2.2E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS01200 6339945fa93c8c71839e0e90cedf5170 284 Gene3D G3DSA:3.40.50.880 54 278 9.1E-38 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS01200 6339945fa93c8c71839e0e90cedf5170 284 SUPERFAMILY SSF52317 64 276 2.81E-35 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS01200 6339945fa93c8c71839e0e90cedf5170 284 Pfam PF07722 Peptidase C26 51 256 1.3E-52 T 06-07-2017 IPR011697 Peptidase C26 GO:0006541|GO:0016787 SMD11_RS19910 79ec9b5eb605f5437c732bfaaf88d05a 169 Pfam PF06897 Protein of unknown function (DUF1269) 70 150 9.6E-7 T 06-07-2017 IPR009200 Protein of unknown function DUF1269, membrane associated SMD11_RS19680 ad58ed74e5fbb3a84517c16ba4c5ad86 264 SUPERFAMILY SSF53213 11 264 7.59E-84 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 SMD11_RS19680 ad58ed74e5fbb3a84517c16ba4c5ad86 264 Gene3D G3DSA:3.40.830.10 10 263 9.1E-87 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 SMD11_RS19680 ad58ed74e5fbb3a84517c16ba4c5ad86 264 PIRSF PIRSF006157 8 264 1.1E-85 T 06-07-2017 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA type GO:0008270|GO:0016701|GO:0055114 SMD11_RS19680 ad58ed74e5fbb3a84517c16ba4c5ad86 264 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 33 241 2.1E-41 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 SMD11_RS16680 5ba2acb3bc95b28ce6101049c02a389a 414 Gene3D G3DSA:1.20.1250.20 5 187 2.7E-26 T 06-07-2017 SMD11_RS16680 5ba2acb3bc95b28ce6101049c02a389a 414 SUPERFAMILY SSF103473 3 376 4.32E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS16680 5ba2acb3bc95b28ce6101049c02a389a 414 Pfam PF07690 Major Facilitator Superfamily 8 309 7.3E-40 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS16680 5ba2acb3bc95b28ce6101049c02a389a 414 Gene3D G3DSA:1.20.1250.20 197 373 3.8E-16 T 06-07-2017 SMD11_RS19245 1232fd50d32829c76ddd9352d5d0b061 103 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 95 19.537 T 06-07-2017 IPR003482 Transcription factor WhiB SMD11_RS19245 1232fd50d32829c76ddd9352d5d0b061 103 Pfam PF02467 Transcription factor WhiB 17 87 4.3E-25 T 06-07-2017 IPR003482 Transcription factor WhiB SMD11_RS00405 23d39e8906ea361b17d8dad65a61dd53 203 SUPERFAMILY SSF53335 10 165 2.84E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS00405 23d39e8906ea361b17d8dad65a61dd53 203 Pfam PF08241 Methyltransferase domain 28 124 4.7E-16 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS00405 23d39e8906ea361b17d8dad65a61dd53 203 Gene3D G3DSA:3.40.50.150 17 137 3.6E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS20855 c3384ade96e689765ac7d2e6881fc271 359 Gene3D G3DSA:2.160.10.10 259 349 7.1E-16 T 06-07-2017 SMD11_RS20855 c3384ade96e689765ac7d2e6881fc271 359 Pfam PF00483 Nucleotidyl transferase 4 237 3.7E-43 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMD11_RS20855 c3384ade96e689765ac7d2e6881fc271 359 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 259 287 0.0024 T 06-07-2017 IPR001451 Hexapeptide repeat SMD11_RS20855 c3384ade96e689765ac7d2e6881fc271 359 SUPERFAMILY SSF53448 3 241 2.93E-66 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20855 c3384ade96e689765ac7d2e6881fc271 359 SUPERFAMILY SSF53448 285 301 2.93E-66 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20855 c3384ade96e689765ac7d2e6881fc271 359 Gene3D G3DSA:3.90.550.10 1 238 3.1E-63 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20855 c3384ade96e689765ac7d2e6881fc271 359 SUPERFAMILY SSF51161 256 351 1.29E-15 T 06-07-2017 IPR011004 Trimeric LpxA-like SMD11_RS07455 8253d50a08bb88c697eaa613ac965252 266 Pfam PF11452 Protein of unknown function (DUF3000) 21 247 1.3E-67 T 06-07-2017 IPR021555 Protein of unknown function DUF3000 SMD11_RS22575 752ffc3d99e3787d1c890a62f09fe68f 263 Gene3D G3DSA:3.30.2140.10 4 88 7.2E-55 T 06-07-2017 SMD11_RS22575 752ffc3d99e3787d1c890a62f09fe68f 263 Gene3D G3DSA:3.30.2140.10 180 253 7.2E-55 T 06-07-2017 SMD11_RS22575 752ffc3d99e3787d1c890a62f09fe68f 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 48 71 3.4E-12 T 06-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD11_RS22575 752ffc3d99e3787d1c890a62f09fe68f 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 72 94 3.4E-12 T 06-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD11_RS22575 752ffc3d99e3787d1c890a62f09fe68f 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 24 47 3.4E-12 T 06-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD11_RS22575 752ffc3d99e3787d1c890a62f09fe68f 263 SUPERFAMILY SSF54001 2 250 7.36E-69 T 06-07-2017 SMD11_RS22575 752ffc3d99e3787d1c890a62f09fe68f 263 Pfam PF00797 N-acetyltransferase 27 250 1.8E-66 T 06-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 SMD11_RS27785 a2082530ba145a4b7f072c364864a984 277 Gene3D G3DSA:3.40.50.300 3 228 3.0E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27785 a2082530ba145a4b7f072c364864a984 277 SUPERFAMILY SSF52540 3 224 7.56E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27785 a2082530ba145a4b7f072c364864a984 277 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS27785 a2082530ba145a4b7f072c364864a984 277 Pfam PF00005 ABC transporter 20 167 4.3E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS27785 a2082530ba145a4b7f072c364864a984 277 SMART SM00382 27 211 4.6E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS03555 bfc8515457e9fc9a5fc333cdd25fa580 442 ProSitePatterns PS00217 Sugar transport proteins signature 2. 143 168 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS03555 bfc8515457e9fc9a5fc333cdd25fa580 442 ProSitePatterns PS00216 Sugar transport proteins signature 1. 310 327 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS03555 bfc8515457e9fc9a5fc333cdd25fa580 442 Gene3D G3DSA:1.20.1250.20 254 438 6.0E-23 T 06-07-2017 SMD11_RS03555 bfc8515457e9fc9a5fc333cdd25fa580 442 Gene3D G3DSA:1.20.1250.20 30 232 2.7E-22 T 06-07-2017 SMD11_RS03555 bfc8515457e9fc9a5fc333cdd25fa580 442 SUPERFAMILY SSF103473 17 441 1.57E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS03555 bfc8515457e9fc9a5fc333cdd25fa580 442 Pfam PF07690 Major Facilitator Superfamily 77 298 7.6E-22 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS31425 ec6517a990c42a861ed8b1ce924e38c2 435 Gene3D G3DSA:3.65.10.10 224 429 1.3E-22 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD11_RS31425 ec6517a990c42a861ed8b1ce924e38c2 435 SUPERFAMILY SSF55205 7 429 2.29E-45 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SMD11_RS31425 ec6517a990c42a861ed8b1ce924e38c2 435 Gene3D G3DSA:3.65.10.10 26 222 1.1E-19 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD11_RS31425 ec6517a990c42a861ed8b1ce924e38c2 435 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 420 4.5E-27 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 SMD11_RS29670 7268c66146cf88f055a3c7efe7498075 142 Gene3D G3DSA:3.30.1330.40 13 139 1.0E-42 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD11_RS29670 7268c66146cf88f055a3c7efe7498075 142 Pfam PF01042 Endoribonuclease L-PSP 21 137 1.5E-29 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family SMD11_RS29670 7268c66146cf88f055a3c7efe7498075 142 SUPERFAMILY SSF55298 14 138 2.36E-34 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD11_RS00270 16096ca286b7dfadf9807f5cf6634519 160 Pfam PF00535 Glycosyl transferase family 2 64 120 3.2E-6 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD11_RS00270 16096ca286b7dfadf9807f5cf6634519 160 Gene3D G3DSA:3.90.550.10 62 119 9.7E-5 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS00270 16096ca286b7dfadf9807f5cf6634519 160 SUPERFAMILY SSF53448 60 124 4.5E-10 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS21575 e8caa537b8226197cb82ab63439d9547 252 SUPERFAMILY SSF55781 77 242 1.24E-23 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS21575 e8caa537b8226197cb82ab63439d9547 252 Pfam PF01614 Bacterial transcriptional regulator 133 228 6.9E-15 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal SMD11_RS21575 e8caa537b8226197cb82ab63439d9547 252 Gene3D G3DSA:3.30.450.40 85 241 2.0E-27 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS21575 e8caa537b8226197cb82ab63439d9547 252 SUPERFAMILY SSF46785 12 79 3.34E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21575 e8caa537b8226197cb82ab63439d9547 252 Pfam PF09339 IclR helix-turn-helix domain 14 62 1.0E-6 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS21575 e8caa537b8226197cb82ab63439d9547 252 Gene3D G3DSA:1.10.10.10 10 79 5.4E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS29870 865451f16cbae748d12dd089c8d49e09 288 Pfam PF12697 Alpha/beta hydrolase family 40 273 7.4E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS29870 865451f16cbae748d12dd089c8d49e09 288 SUPERFAMILY SSF53474 210 269 6.95E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS29870 865451f16cbae748d12dd089c8d49e09 288 SUPERFAMILY SSF53474 14 153 6.95E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS29870 865451f16cbae748d12dd089c8d49e09 288 Gene3D G3DSA:3.40.50.1820 15 152 5.0E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS29870 865451f16cbae748d12dd089c8d49e09 288 Gene3D G3DSA:3.40.50.1820 209 267 5.0E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS19345 7c9c1c682b91f94d70df2b045101a009 487 Pfam PF00171 Aldehyde dehydrogenase family 12 482 2.8E-157 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS19345 7c9c1c682b91f94d70df2b045101a009 487 Gene3D G3DSA:3.40.309.10 268 458 9.5E-63 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS19345 7c9c1c682b91f94d70df2b045101a009 487 SUPERFAMILY SSF53720 2 484 5.76E-153 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS19345 7c9c1c682b91f94d70df2b045101a009 487 Gene3D G3DSA:3.40.605.10 3 267 6.4E-86 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS08725 e7695798e94df6cc1904a4d12c1f2e80 253 Gene3D G3DSA:3.90.79.10 3 164 5.6E-48 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS08725 e7695798e94df6cc1904a4d12c1f2e80 253 Gene3D G3DSA:1.10.10.10 168 241 5.4E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08725 e7695798e94df6cc1904a4d12c1f2e80 253 SUPERFAMILY SSF55811 5 173 2.71E-28 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS08725 e7695798e94df6cc1904a4d12c1f2e80 253 Pfam PF00293 NUDIX domain 14 138 1.6E-18 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS08725 e7695798e94df6cc1904a4d12c1f2e80 253 SUPERFAMILY SSF46785 176 246 2.04E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08725 e7695798e94df6cc1904a4d12c1f2e80 253 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD11_RS32780 72c185e8853a7913470ac414ee8a7d3f 546 Gene3D G3DSA:3.30.2010.10 75 164 1.1E-10 T 06-07-2017 SMD11_RS32780 72c185e8853a7913470ac414ee8a7d3f 546 Pfam PF01435 Peptidase family M48 91 348 4.3E-10 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMD11_RS15045 fdef6b3e5434e2c3b15a621bc6eda1dc 84 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 8.4E-18 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS15045 fdef6b3e5434e2c3b15a621bc6eda1dc 84 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS15045 fdef6b3e5434e2c3b15a621bc6eda1dc 84 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 25.402 T 06-07-2017 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS15045 fdef6b3e5434e2c3b15a621bc6eda1dc 84 Pfam PF01197 Ribosomal protein L31 1 79 1.3E-27 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS15045 fdef6b3e5434e2c3b15a621bc6eda1dc 84 SUPERFAMILY SSF143800 1 80 1.88E-20 T 06-07-2017 SMD11_RS15045 fdef6b3e5434e2c3b15a621bc6eda1dc 84 PRINTS PR01249 Ribosomal protein L31 signature 60 78 5.1E-16 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS15045 fdef6b3e5434e2c3b15a621bc6eda1dc 84 PRINTS PR01249 Ribosomal protein L31 signature 45 60 5.1E-16 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS15045 fdef6b3e5434e2c3b15a621bc6eda1dc 84 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.1E-16 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS26935 a4100de227936df06d48a69608354890 225 SMART SM00563 34 153 2.0E-31 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD11_RS26935 a4100de227936df06d48a69608354890 225 Gene3D G3DSA:3.40.1130.10 8 206 4.6E-30 T 06-07-2017 SMD11_RS26935 a4100de227936df06d48a69608354890 225 SUPERFAMILY SSF69593 6 220 3.14E-46 T 06-07-2017 SMD11_RS26935 a4100de227936df06d48a69608354890 225 Pfam PF01553 Acyltransferase 20 150 3.0E-21 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD11_RS20780 9217f38d2e7191571cd2f5ee8b3f56c4 225 SUPERFAMILY SSF52172 4 176 6.12E-43 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS20780 9217f38d2e7191571cd2f5ee8b3f56c4 225 Gene3D G3DSA:3.40.50.2300 2 123 2.9E-40 T 06-07-2017 SMD11_RS20780 9217f38d2e7191571cd2f5ee8b3f56c4 225 Gene3D G3DSA:1.10.10.10 124 222 5.0E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20780 9217f38d2e7191571cd2f5ee8b3f56c4 225 Pfam PF00072 Response regulator receiver domain 5 114 1.2E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS20780 9217f38d2e7191571cd2f5ee8b3f56c4 225 SMART SM00448 3 113 5.3E-44 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS20780 9217f38d2e7191571cd2f5ee8b3f56c4 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 1.8E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS20780 9217f38d2e7191571cd2f5ee8b3f56c4 225 SMART SM00862 146 222 3.3E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS22565 39df52490f408ac0a3cf4584e756d45f 290 Pfam PF10531 SLBB domain 150 204 2.2E-9 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS22565 39df52490f408ac0a3cf4584e756d45f 290 Gene3D G3DSA:3.10.560.10 149 202 5.4E-5 T 06-07-2017 SMD11_RS21285 90ad0dc7cccfd2ccb894bb37461d227d 500 SUPERFAMILY SSF103473 37 475 7.59E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS21285 90ad0dc7cccfd2ccb894bb37461d227d 500 Gene3D G3DSA:1.20.1250.20 287 472 1.1E-18 T 06-07-2017 SMD11_RS21285 90ad0dc7cccfd2ccb894bb37461d227d 500 Gene3D G3DSA:1.20.1250.20 52 260 1.1E-25 T 06-07-2017 SMD11_RS21285 90ad0dc7cccfd2ccb894bb37461d227d 500 ProSitePatterns PS00217 Sugar transport proteins signature 2. 164 189 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS21285 90ad0dc7cccfd2ccb894bb37461d227d 500 Pfam PF00083 Sugar (and other) transporter 57 476 1.3E-42 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMD11_RS23695 f933f16a38e6df7ee30bf54804ea9e48 320 Pfam PF03239 Iron permease FTR1 family 1 260 5.0E-68 T 06-07-2017 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 SMD11_RS09095 24285403465a9e02130d7bc9e88d3fd1 250 PIRSF PIRSF000161 2 250 5.0E-62 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS09095 24285403465a9e02130d7bc9e88d3fd1 250 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 43 248 3.4E-54 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS09095 24285403465a9e02130d7bc9e88d3fd1 250 SUPERFAMILY SSF51735 4 135 1.13E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS09095 24285403465a9e02130d7bc9e88d3fd1 250 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 248 28.528 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS09095 24285403465a9e02130d7bc9e88d3fd1 250 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 130 147 - T 06-07-2017 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS09095 24285403465a9e02130d7bc9e88d3fd1 250 Gene3D G3DSA:3.30.360.10 125 216 7.3E-32 T 06-07-2017 SMD11_RS09095 24285403465a9e02130d7bc9e88d3fd1 250 Gene3D G3DSA:3.40.50.720 2 124 6.9E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS09095 24285403465a9e02130d7bc9e88d3fd1 250 SUPERFAMILY SSF55347 109 217 1.68E-37 T 06-07-2017 SMD11_RS09095 24285403465a9e02130d7bc9e88d3fd1 250 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 108 1.7E-23 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS09095 24285403465a9e02130d7bc9e88d3fd1 250 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 111 247 2.8E-28 T 06-07-2017 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS28715 9c130aecd3aac1c404e3816732dab352 243 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS28715 9c130aecd3aac1c404e3816732dab352 243 SMART SM00382 28 206 4.9E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS28715 9c130aecd3aac1c404e3816732dab352 243 Pfam PF00005 ABC transporter 20 158 1.2E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS28715 9c130aecd3aac1c404e3816732dab352 243 Gene3D G3DSA:3.40.50.300 4 222 5.2E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28715 9c130aecd3aac1c404e3816732dab352 243 SUPERFAMILY SSF52540 4 227 5.89E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05985 904852f3b49676ad67db9fc6d4b4d70f 276 Gene3D G3DSA:1.10.260.40 12 81 7.8E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS17020 983cedcae7b6dd0bc6b5dd464dd92abd 224 TIGRFAM TIGR01076 sortase_fam: sortase 71 209 2.3E-14 T 06-07-2017 IPR005754 Sortase family SMD11_RS17020 983cedcae7b6dd0bc6b5dd464dd92abd 224 Pfam PF04203 Sortase family 72 209 7.5E-27 T 06-07-2017 IPR005754 Sortase family SMD11_RS17020 983cedcae7b6dd0bc6b5dd464dd92abd 224 Gene3D G3DSA:2.40.260.10 66 212 4.4E-29 T 06-07-2017 IPR023365 Sortase domain SMD11_RS17020 983cedcae7b6dd0bc6b5dd464dd92abd 224 SUPERFAMILY SSF63817 65 211 1.19E-30 T 06-07-2017 IPR023365 Sortase domain SMD11_RS01920 a19d8676056b5ff7a8f41f88482e6dc9 414 Pfam PF07690 Major Facilitator Superfamily 22 236 4.0E-32 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS01920 a19d8676056b5ff7a8f41f88482e6dc9 414 SUPERFAMILY SSF103473 19 395 3.14E-60 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS01920 a19d8676056b5ff7a8f41f88482e6dc9 414 Gene3D G3DSA:1.20.1250.20 21 191 3.5E-29 T 06-07-2017 SMD11_RS01920 a19d8676056b5ff7a8f41f88482e6dc9 414 Gene3D G3DSA:1.20.1250.20 212 390 3.4E-17 T 06-07-2017 SMD11_RS12530 ee2bf010dce8b236839ecec59f3dbd0d 98 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 70 97 1.5E-5 T 06-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS12530 ee2bf010dce8b236839ecec59f3dbd0d 98 Gene3D G3DSA:3.30.1390.10 71 97 2.3E-5 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMD11_RS13310 7e5e2ec7fb652a24c5045261a3bdc28d 227 SMART SM00448 11 130 1.4E-16 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS13310 7e5e2ec7fb652a24c5045261a3bdc28d 227 Gene3D G3DSA:3.40.50.2300 5 132 2.5E-24 T 06-07-2017 SMD11_RS13310 7e5e2ec7fb652a24c5045261a3bdc28d 227 Pfam PF00072 Response regulator receiver domain 13 130 4.3E-16 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS13310 7e5e2ec7fb652a24c5045261a3bdc28d 227 SUPERFAMILY SSF46894 157 226 1.9E-23 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS13310 7e5e2ec7fb652a24c5045261a3bdc28d 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 221 8.8E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13310 7e5e2ec7fb652a24c5045261a3bdc28d 227 SMART SM00421 164 221 6.0E-26 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13310 7e5e2ec7fb652a24c5045261a3bdc28d 227 Gene3D G3DSA:1.10.10.10 133 227 8.0E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13310 7e5e2ec7fb652a24c5045261a3bdc28d 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 181 208 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13310 7e5e2ec7fb652a24c5045261a3bdc28d 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 9.5E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13310 7e5e2ec7fb652a24c5045261a3bdc28d 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 9.5E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13310 7e5e2ec7fb652a24c5045261a3bdc28d 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 9.5E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13310 7e5e2ec7fb652a24c5045261a3bdc28d 227 SUPERFAMILY SSF52172 11 148 4.84E-22 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS25060 9dedfd90b941144e79b6e7afeb60ebcd 229 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 209 1.2E-33 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD11_RS25060 9dedfd90b941144e79b6e7afeb60ebcd 229 SUPERFAMILY SSF109854 1 147 5.8E-39 T 06-07-2017 SMD11_RS25060 9dedfd90b941144e79b6e7afeb60ebcd 229 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 140 1.5E-21 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD11_RS25060 9dedfd90b941144e79b6e7afeb60ebcd 229 SUPERFAMILY SSF55718 148 228 4.71E-15 T 06-07-2017 IPR003033 SCP2 sterol-binding domain SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 SMART SM00091 105 171 1.1E-5 T 06-07-2017 IPR000014 PAS domain SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 SMART SM00091 229 296 2.4E-5 T 06-07-2017 IPR000014 PAS domain SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 Gene3D G3DSA:3.30.450.20 215 331 7.3E-11 T 06-07-2017 SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 352 366 1.3E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 382 394 1.3E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 366 382 1.3E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 SMART SM00421 349 406 4.6E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 SUPERFAMILY SSF55785 104 215 3.77E-17 T 06-07-2017 IPR000014 PAS domain SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 SUPERFAMILY SSF46894 337 412 4.42E-14 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 Pfam PF00196 Bacterial regulatory proteins, luxR family 351 405 5.2E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 Gene3D G3DSA:1.10.10.10 346 411 1.2E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 Gene3D G3DSA:3.30.450.20 104 214 4.4E-18 T 06-07-2017 SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 225 339 3.7E-7 T 06-07-2017 IPR000014 PAS domain SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 106 220 6.1E-10 T 06-07-2017 IPR000014 PAS domain SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 SUPERFAMILY SSF55785 213 315 1.03E-12 T 06-07-2017 IPR000014 PAS domain SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 Pfam PF08448 PAS fold 112 215 5.5E-11 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS27615 86fb55ecaf18aa9f80352ea952a40dd2 431 Pfam PF08448 PAS fold 236 331 3.8E-7 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS33765 2a27a3f84998df134cb0d32e323fd20e 146 Gene3D G3DSA:2.60.200.20 45 131 2.0E-10 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS33765 2a27a3f84998df134cb0d32e323fd20e 146 SUPERFAMILY SSF49879 47 137 9.76E-12 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 SMD11_RS33765 2a27a3f84998df134cb0d32e323fd20e 146 Pfam PF00498 FHA domain 58 130 2.9E-5 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS07360 eb5ae695f033ce7133f50af7d8c114b3 288 Pfam PF01522 Polysaccharide deacetylase 70 207 2.3E-21 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS07360 eb5ae695f033ce7133f50af7d8c114b3 288 Gene3D G3DSA:3.20.20.370 57 279 1.2E-40 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS07360 eb5ae695f033ce7133f50af7d8c114b3 288 SUPERFAMILY SSF88713 64 279 7.91E-40 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS18005 dd1e4083722d31b64ce3d21e2701e9d9 750 SMART SM00487 73 273 6.9E-52 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS18005 dd1e4083722d31b64ce3d21e2701e9d9 750 SMART SM00490 307 388 2.4E-28 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS18005 dd1e4083722d31b64ce3d21e2701e9d9 750 Gene3D G3DSA:3.40.50.300 264 412 2.4E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18005 dd1e4083722d31b64ce3d21e2701e9d9 750 Pfam PF00270 DEAD/DEAH box helicase 78 246 4.3E-45 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD11_RS18005 dd1e4083722d31b64ce3d21e2701e9d9 750 Gene3D G3DSA:3.40.50.300 42 263 2.5E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18005 dd1e4083722d31b64ce3d21e2701e9d9 750 Pfam PF00271 Helicase conserved C-terminal domain 290 388 6.4E-23 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS18005 dd1e4083722d31b64ce3d21e2701e9d9 750 SUPERFAMILY SSF52540 125 409 2.64E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00490 de14299dbd762e6fb9f09d4dad143426 583 Pfam PF00733 Asparagine synthase 190 554 3.4E-25 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMD11_RS00490 de14299dbd762e6fb9f09d4dad143426 583 SUPERFAMILY SSF52402 427 551 2.79E-23 T 06-07-2017 SMD11_RS00490 de14299dbd762e6fb9f09d4dad143426 583 SUPERFAMILY SSF52402 188 327 2.79E-23 T 06-07-2017 SMD11_RS00490 de14299dbd762e6fb9f09d4dad143426 583 Gene3D G3DSA:3.40.50.620 422 568 1.5E-20 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS00490 de14299dbd762e6fb9f09d4dad143426 583 Gene3D G3DSA:3.40.50.620 187 323 1.5E-20 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS00490 de14299dbd762e6fb9f09d4dad143426 583 Gene3D G3DSA:3.60.20.10 69 162 9.2E-6 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS31735 f225c622f028ba98cf7a724088602f80 407 SUPERFAMILY SSF48264 14 406 1.83E-74 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS31735 f225c622f028ba98cf7a724088602f80 407 PRINTS PR00359 B-class P450 signature 162 177 1.5E-28 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31735 f225c622f028ba98cf7a724088602f80 407 PRINTS PR00359 B-class P450 signature 145 161 1.5E-28 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31735 f225c622f028ba98cf7a724088602f80 407 PRINTS PR00359 B-class P450 signature 297 324 1.5E-28 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31735 f225c622f028ba98cf7a724088602f80 407 PRINTS PR00359 B-class P450 signature 346 355 1.5E-28 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31735 f225c622f028ba98cf7a724088602f80 407 PRINTS PR00359 B-class P450 signature 355 366 1.5E-28 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31735 f225c622f028ba98cf7a724088602f80 407 PRINTS PR00359 B-class P450 signature 99 110 1.5E-28 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31735 f225c622f028ba98cf7a724088602f80 407 PRINTS PR00359 B-class P450 signature 198 220 1.5E-28 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31735 f225c622f028ba98cf7a724088602f80 407 PRINTS PR00359 B-class P450 signature 278 289 1.5E-28 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31735 f225c622f028ba98cf7a724088602f80 407 PRINTS PR00359 B-class P450 signature 325 340 1.5E-28 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31735 f225c622f028ba98cf7a724088602f80 407 Pfam PF00067 Cytochrome P450 208 376 2.7E-17 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS31735 f225c622f028ba98cf7a724088602f80 407 Gene3D G3DSA:1.10.630.10 13 406 2.3E-94 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS26590 24e6e9a1e59a6b3d20066c8aad69045b 297 SUPERFAMILY SSF111331 4 294 5.23E-64 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMD11_RS26590 24e6e9a1e59a6b3d20066c8aad69045b 297 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 116 1.2E-23 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMD11_RS26590 24e6e9a1e59a6b3d20066c8aad69045b 297 SMART SM00046 4 131 0.0018 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMD11_RS27285 17e465d03699ec62e19dd8f9d164af70 537 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 224 535 2.4E-43 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like SMD11_RS27285 17e465d03699ec62e19dd8f9d164af70 537 Gene3D G3DSA:3.30.160.60 503 536 0.001 T 06-07-2017 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 SMD11_RS27285 17e465d03699ec62e19dd8f9d164af70 537 Pfam PF02618 YceG-like family 229 527 8.2E-64 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like SMD11_RS30805 fdb7743773b2245960754b4b299342a7 307 SUPERFAMILY SSF56281 56 298 1.11E-35 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS30805 fdb7743773b2245960754b4b299342a7 307 Pfam PF00753 Metallo-beta-lactamase superfamily 73 281 7.7E-22 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS30805 fdb7743773b2245960754b4b299342a7 307 SMART SM00849 70 281 3.1E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS30805 fdb7743773b2245960754b4b299342a7 307 Gene3D G3DSA:3.60.15.10 15 299 3.1E-45 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS01125 0c5d8904df880db9a3cd2331f50a6cfd 382 Pfam PF00264 Common central domain of tyrosinase 73 293 1.1E-34 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS01125 0c5d8904df880db9a3cd2331f50a6cfd 382 ProSitePatterns PS00498 Tyrosinase and hemocyanins CuB-binding region signature. 273 284 - T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS01125 0c5d8904df880db9a3cd2331f50a6cfd 382 SUPERFAMILY SSF48056 200 378 1.44E-52 T 06-07-2017 IPR008922 Uncharacterised domain, di-copper centre SMD11_RS01125 0c5d8904df880db9a3cd2331f50a6cfd 382 SUPERFAMILY SSF48056 38 172 1.44E-52 T 06-07-2017 IPR008922 Uncharacterised domain, di-copper centre SMD11_RS01125 0c5d8904df880db9a3cd2331f50a6cfd 382 Gene3D G3DSA:1.10.1280.10 9 378 5.5E-55 T 06-07-2017 IPR008922 Uncharacterised domain, di-copper centre SMD11_RS01125 0c5d8904df880db9a3cd2331f50a6cfd 382 PRINTS PR00092 Tyrosinase copper-binding domain signature 272 290 2.1E-14 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS01125 0c5d8904df880db9a3cd2331f50a6cfd 382 PRINTS PR00092 Tyrosinase copper-binding domain signature 103 120 2.1E-14 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS01125 0c5d8904df880db9a3cd2331f50a6cfd 382 PRINTS PR00092 Tyrosinase copper-binding domain signature 132 137 2.1E-14 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS01125 0c5d8904df880db9a3cd2331f50a6cfd 382 PRINTS PR00092 Tyrosinase copper-binding domain signature 253 264 2.1E-14 T 06-07-2017 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 SMD11_RS22735 8601aa0e7f4496af93325783364081c9 363 SUPERFAMILY SSF48452 9 217 2.28E-24 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS22735 8601aa0e7f4496af93325783364081c9 363 Pfam PF13432 Tetratricopeptide repeat 10 66 1.2E-5 T 06-07-2017 SMD11_RS22735 8601aa0e7f4496af93325783364081c9 363 Pfam PF13432 Tetratricopeptide repeat 128 178 0.003 T 06-07-2017 SMD11_RS22735 8601aa0e7f4496af93325783364081c9 363 Gene3D G3DSA:1.25.40.10 9 226 7.1E-32 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS22735 8601aa0e7f4496af93325783364081c9 363 SMART SM00028 144 177 65.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS22735 8601aa0e7f4496af93325783364081c9 363 SMART SM00028 39 72 9.4 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS22735 8601aa0e7f4496af93325783364081c9 363 SMART SM00028 73 106 190.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS24735 757d2e6175384efed11cf0bcb760c3c7 217 TIGRFAM TIGR02234 trp_oprn_chp: membrane protein, TIGR02234 family 23 213 1.6E-46 T 06-07-2017 IPR011746 Trp biosynthesis associated, conserved hypothetical membrane protein SMD11_RS24735 757d2e6175384efed11cf0bcb760c3c7 217 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 31 212 2.1E-52 T 06-07-2017 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp SMD11_RS19270 4b233a9b4569431acf71470b0396615f 203 SUPERFAMILY SSF81995 3 68 1.52E-7 T 06-07-2017 SMD11_RS13055 846033ec7c43cac203097737323a331a 188 Gene3D G3DSA:1.10.3330.10 22 164 4.5E-22 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 SMD11_RS13055 846033ec7c43cac203097737323a331a 188 SUPERFAMILY SSF158694 13 162 1.29E-23 T 06-07-2017 SMD11_RS13055 846033ec7c43cac203097737323a331a 188 Pfam PF09349 OHCU decarboxylase 91 159 2.1E-7 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 SMD11_RS25155 d957dfc915ab47970543f58f6a57333a 359 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 51 299 1.2E-82 T 06-07-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA SMD11_RS25155 d957dfc915ab47970543f58f6a57333a 359 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 1 299 1.2E-95 T 06-07-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA SMD11_RS16385 b3c7b48321cbdd91c332a20f55e34671 91 SUPERFAMILY SSF47336 8 84 2.75E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS16385 b3c7b48321cbdd91c332a20f55e34671 91 Pfam PF00550 Phosphopantetheine attachment site 13 74 8.5E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS16385 b3c7b48321cbdd91c332a20f55e34671 91 Gene3D G3DSA:1.10.1200.10 7 86 3.7E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS17275 0698ec908c02f329f212fb06a46627f7 260 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 143 163 - T 06-07-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site SMD11_RS17275 0698ec908c02f329f212fb06a46627f7 260 SUPERFAMILY SSF56317 1 256 1.27E-70 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS17275 0698ec908c02f329f212fb06a46627f7 260 Gene3D G3DSA:3.60.110.10 1 256 4.6E-77 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS17275 0698ec908c02f329f212fb06a46627f7 260 Pfam PF00795 Carbon-nitrogen hydrolase 3 247 8.8E-44 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS27315 c8fa905ca9ca19b276977944395d097a 217 SUPERFAMILY SSF52540 32 206 6.84E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27315 c8fa905ca9ca19b276977944395d097a 217 Pfam PF13671 AAA domain 36 168 4.7E-9 T 06-07-2017 SMD11_RS27315 c8fa905ca9ca19b276977944395d097a 217 Gene3D G3DSA:3.40.50.300 36 207 2.4E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30240 d1323c55f94fd8378a3745b1d1d84cbd 655 Pfam PF13185 GAF domain 102 245 1.2E-15 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS30240 d1323c55f94fd8378a3745b1d1d84cbd 655 SUPERFAMILY SSF55781 86 271 4.14E-28 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS30240 d1323c55f94fd8378a3745b1d1d84cbd 655 Pfam PF13556 PucR C-terminal helix-turn-helix domain 588 646 5.8E-17 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain SMD11_RS30240 d1323c55f94fd8378a3745b1d1d84cbd 655 SMART SM00065 103 254 1.2E-18 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS30240 d1323c55f94fd8378a3745b1d1d84cbd 655 Gene3D G3DSA:3.30.450.40 78 261 1.1E-32 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS08620 176d37ec4e678ec920b2bb025a52c119 93 Pfam PF00381 PTS HPr component phosphorylation site 3 83 3.9E-20 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like SMD11_RS08620 176d37ec4e678ec920b2bb025a52c119 93 PRINTS PR00107 Phosphocarrier protein signature 13 29 7.0E-10 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like SMD11_RS08620 176d37ec4e678ec920b2bb025a52c119 93 PRINTS PR00107 Phosphocarrier protein signature 39 54 7.0E-10 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like SMD11_RS08620 176d37ec4e678ec920b2bb025a52c119 93 PRINTS PR00107 Phosphocarrier protein signature 54 71 7.0E-10 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like SMD11_RS08620 176d37ec4e678ec920b2bb025a52c119 93 SUPERFAMILY SSF55594 1 88 2.62E-18 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like SMD11_RS08620 176d37ec4e678ec920b2bb025a52c119 93 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 3.6E-24 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like SMD11_RS08620 176d37ec4e678ec920b2bb025a52c119 93 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 06-07-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site SMD11_RS08620 176d37ec4e678ec920b2bb025a52c119 93 Gene3D G3DSA:3.30.1340.10 1 88 4.2E-23 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like SMD11_RS22110 cfbaa4637e60cc4b64232f4e997e2e6b 320 Gene3D G3DSA:1.10.3720.10 15 309 3.7E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS22110 cfbaa4637e60cc4b64232f4e997e2e6b 320 SUPERFAMILY SSF161098 65 305 1.31E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS22110 cfbaa4637e60cc4b64232f4e997e2e6b 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 305 1.3E-7 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS24510 58bc1b53338796f218153fc117ea7664 463 Pfam PF01098 Cell cycle protein 80 430 4.1E-93 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 SMD11_RS24510 58bc1b53338796f218153fc117ea7664 463 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 75 431 2.0E-113 T 06-07-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 SMD11_RS24510 58bc1b53338796f218153fc117ea7664 463 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 390 414 - T 06-07-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 SMD11_RS33205 dd7e98520e9bd3aa162a009a2e5472cd 189 Gene3D G3DSA:3.40.50.300 4 136 1.2E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS33205 dd7e98520e9bd3aa162a009a2e5472cd 189 SUPERFAMILY SSF52540 1 178 4.8E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27145 e12ff90f5f27c5f557d2b32cb82607bf 218 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 5.8E-10 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD11_RS27145 e12ff90f5f27c5f557d2b32cb82607bf 218 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD11_RS20215 4a74fd9ab8bae00c7313c62555528030 654 Gene3D G3DSA:2.60.40.920 414 487 6.4E-4 T 06-07-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain SMD11_RS20215 4a74fd9ab8bae00c7313c62555528030 654 Pfam PF13406 Transglycosylase SLT domain 215 262 2.9E-8 T 06-07-2017 IPR031304 Transglycosylase SLT domain 2 SMD11_RS20215 4a74fd9ab8bae00c7313c62555528030 654 Gene3D G3DSA:1.10.530.10 212 296 4.0E-9 T 06-07-2017 SMD11_RS20215 4a74fd9ab8bae00c7313c62555528030 654 Gene3D G3DSA:1.10.530.10 151 173 4.0E-9 T 06-07-2017 SMD11_RS20215 4a74fd9ab8bae00c7313c62555528030 654 SUPERFAMILY SSF53955 120 297 4.87E-35 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS32960 49fc1e8d46cfa4a92bda32b9c2c8c714 283 ProSitePatterns PS00801 Transketolase signature 1. 19 39 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS32960 49fc1e8d46cfa4a92bda32b9c2c8c714 283 SUPERFAMILY SSF52518 9 266 4.91E-83 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS32960 49fc1e8d46cfa4a92bda32b9c2c8c714 283 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 14 262 1.0E-43 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SMD11_RS32960 49fc1e8d46cfa4a92bda32b9c2c8c714 283 Gene3D G3DSA:3.40.50.970 8 272 1.7E-90 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS07405 925c4a82779f547e823f930d49d97843 403 Pfam PF01494 FAD binding domain 3 343 1.9E-79 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS07405 925c4a82779f547e823f930d49d97843 403 SUPERFAMILY SSF51905 1 170 1.2E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07405 925c4a82779f547e823f930d49d97843 403 SUPERFAMILY SSF51905 274 389 1.2E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07405 925c4a82779f547e823f930d49d97843 403 Gene3D G3DSA:3.30.9.10 153 299 9.8E-62 T 06-07-2017 SMD11_RS07405 925c4a82779f547e823f930d49d97843 403 Gene3D G3DSA:3.50.50.60 3 152 4.8E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS07405 925c4a82779f547e823f930d49d97843 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 1.6E-29 T 06-07-2017 SMD11_RS07405 925c4a82779f547e823f930d49d97843 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 1.6E-29 T 06-07-2017 SMD11_RS07405 925c4a82779f547e823f930d49d97843 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 310 328 1.6E-29 T 06-07-2017 SMD11_RS07405 925c4a82779f547e823f930d49d97843 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 1.6E-29 T 06-07-2017 SMD11_RS07405 925c4a82779f547e823f930d49d97843 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.6E-29 T 06-07-2017 SMD11_RS07405 925c4a82779f547e823f930d49d97843 403 SUPERFAMILY SSF54373 175 275 1.26E-37 T 06-07-2017 SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 SUPERFAMILY SSF52540 183 482 1.76E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 400 478 5.5E-24 T 06-07-2017 IPR032859 GTPase Der, C-terminal KH-domain-like SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 50 170 8.0E-23 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 225 391 1.4E-21 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 Gene3D G3DSA:3.40.50.300 225 405 2.3E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 Gene3D G3DSA:3.40.50.300 49 213 3.0E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 Gene3D G3DSA:3.30.300.20 406 480 9.0E-27 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 PIRSF PIRSF006485 47 486 9.6E-157 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 Hamap MF_00195 GTPase Der [der]. 48 481 35.101 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 50 478 1.9E-155 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 Pfam PF01926 50S ribosome-binding GTPase 51 165 3.7E-25 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 Pfam PF01926 50S ribosome-binding GTPase 226 344 1.1E-20 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 247 1.1E-5 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 276 291 1.1E-5 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 SUPERFAMILY SSF52540 49 215 2.42E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 SMART SM00382 223 366 2.0E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS25870 7d81cef615a9430fd4d027c7a939d3f3 487 SMART SM00382 47 211 0.94 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS01050 346466424b863801e1ca535756d11cbc 404 SUPERFAMILY SSF55874 292 388 2.83E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS01050 346466424b863801e1ca535756d11cbc 404 Pfam PF07730 Histidine kinase 210 278 2.5E-15 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS25195 0d11c42b3688fb53627e8b3d45606a63 259 PIRSF PIRSF006648 4 259 4.2E-34 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS25195 0d11c42b3688fb53627e8b3d45606a63 259 Pfam PF01061 ABC-2 type transporter 33 226 2.6E-22 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD11_RS09225 f342fe6c830c0c12f193a1244bff24d8 303 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 9 229 7.1E-63 T 06-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS09225 f342fe6c830c0c12f193a1244bff24d8 303 SUPERFAMILY SSF88697 246 302 3.48E-9 T 06-07-2017 IPR015947 PUA-like domain SMD11_RS09225 f342fe6c830c0c12f193a1244bff24d8 303 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 8 302 16.491 T 06-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS09225 f342fe6c830c0c12f193a1244bff24d8 303 SUPERFAMILY SSF55120 8 234 1.76E-68 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS09225 f342fe6c830c0c12f193a1244bff24d8 303 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 246 302 3.2E-17 T 06-07-2017 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS09225 f342fe6c830c0c12f193a1244bff24d8 303 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 31 190 1.7E-46 T 06-07-2017 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 SMD11_RS09225 f342fe6c830c0c12f193a1244bff24d8 303 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 191 234 3.7E-11 T 06-07-2017 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 SMD11_RS19710 76a34766c692311b0f3ba4740ccc71e9 253 Gene3D G3DSA:1.10.10.10 5 70 4.4E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19710 76a34766c692311b0f3ba4740ccc71e9 253 Gene3D G3DSA:3.40.50.1360 76 216 3.0E-10 T 06-07-2017 SMD11_RS19710 76a34766c692311b0f3ba4740ccc71e9 253 SMART SM01134 73 234 1.9E-71 T 06-07-2017 SMD11_RS19710 76a34766c692311b0f3ba4740ccc71e9 253 SMART SM00420 6 58 8.9E-14 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS19710 76a34766c692311b0f3ba4740ccc71e9 253 SUPERFAMILY SSF46785 5 58 1.28E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19710 76a34766c692311b0f3ba4740ccc71e9 253 Pfam PF00455 DeoR C terminal sensor domain 76 233 1.5E-50 T 06-07-2017 IPR014036 DeoR C-terminal sensor domain SMD11_RS19710 76a34766c692311b0f3ba4740ccc71e9 253 SUPERFAMILY SSF100950 76 234 3.98E-27 T 06-07-2017 SMD11_RS19710 76a34766c692311b0f3ba4740ccc71e9 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.7E-9 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS19710 76a34766c692311b0f3ba4740ccc71e9 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.7E-9 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS19710 76a34766c692311b0f3ba4740ccc71e9 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 56 1.9E-15 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS18855 a0e41c2799cf2c613b8f5763b914b45c 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 123 2.9E-68 T 06-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18855 a0e41c2799cf2c613b8f5763b914b45c 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18855 a0e41c2799cf2c613b8f5763b914b45c 123 PIRSF PIRSF002133 1 123 8.4E-55 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18855 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 8.4E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18855 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 8.4E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18855 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 8.4E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18855 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 8.4E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18855 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 8.4E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18855 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 8.4E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18855 a0e41c2799cf2c613b8f5763b914b45c 123 Gene3D G3DSA:2.40.50.140 2 123 3.3E-65 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS18855 a0e41c2799cf2c613b8f5763b914b45c 123 Pfam PF00164 Ribosomal protein S12/S23 3 123 1.5E-44 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18855 a0e41c2799cf2c613b8f5763b914b45c 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.977 T 06-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18855 a0e41c2799cf2c613b8f5763b914b45c 123 SUPERFAMILY SSF50249 2 123 6.77E-53 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS19405 7de5c922df6849875261299f539816c7 215 SUPERFAMILY SSF48498 93 200 6.16E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS19405 7de5c922df6849875261299f539816c7 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 62 8.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS19405 7de5c922df6849875261299f539816c7 215 Gene3D G3DSA:1.10.357.10 12 188 2.8E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS19405 7de5c922df6849875261299f539816c7 215 SUPERFAMILY SSF46689 15 76 1.56E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS07200 7f4fbee3a6c2eea4b723a15fc28abdef 227 Gene3D G3DSA:3.40.50.620 8 199 2.9E-54 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS07200 7f4fbee3a6c2eea4b723a15fc28abdef 227 PIRSF PIRSF000857 2 227 8.5E-88 T 06-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 SMD11_RS07200 7f4fbee3a6c2eea4b723a15fc28abdef 227 SUPERFAMILY SSF52402 11 188 2.37E-46 T 06-07-2017 SMD11_RS07200 7f4fbee3a6c2eea4b723a15fc28abdef 227 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 40 202 4.2E-40 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 SMD11_RS07200 7f4fbee3a6c2eea4b723a15fc28abdef 227 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 21 226 5.1E-56 T 06-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 SMD11_RS15975 2462c9c512dbd7331834976b773220fb 224 PIRSF PIRSF001111 2 219 9.1E-91 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS15975 2462c9c512dbd7331834976b773220fb 224 PRINTS PR01398 Isochorismatase signature 62 79 3.2E-49 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS15975 2462c9c512dbd7331834976b773220fb 224 PRINTS PR01398 Isochorismatase signature 79 98 3.2E-49 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS15975 2462c9c512dbd7331834976b773220fb 224 PRINTS PR01398 Isochorismatase signature 185 202 3.2E-49 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS15975 2462c9c512dbd7331834976b773220fb 224 PRINTS PR01398 Isochorismatase signature 111 133 3.2E-49 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS15975 2462c9c512dbd7331834976b773220fb 224 PRINTS PR01398 Isochorismatase signature 167 185 3.2E-49 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS15975 2462c9c512dbd7331834976b773220fb 224 PRINTS PR01398 Isochorismatase signature 3 15 3.2E-49 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS15975 2462c9c512dbd7331834976b773220fb 224 Gene3D G3DSA:3.40.50.850 4 212 5.0E-60 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS15975 2462c9c512dbd7331834976b773220fb 224 SUPERFAMILY SSF52499 3 213 3.27E-60 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS15975 2462c9c512dbd7331834976b773220fb 224 Pfam PF00857 Isochorismatase family 33 202 6.1E-35 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS07065 c559502bd9661b72609634f35cfee55d 348 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 132 337 2.8E-18 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS07065 c559502bd9661b72609634f35cfee55d 348 SUPERFAMILY SSF56219 128 344 1.7E-23 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS07065 c559502bd9661b72609634f35cfee55d 348 Gene3D G3DSA:3.60.10.10 128 344 4.8E-7 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS25200 75a2b5e471725554cd7fe99b844d6dcd 320 SMART SM00382 43 229 3.2E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS25200 75a2b5e471725554cd7fe99b844d6dcd 320 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS25200 75a2b5e471725554cd7fe99b844d6dcd 320 Gene3D G3DSA:3.40.50.300 14 233 1.0E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25200 75a2b5e471725554cd7fe99b844d6dcd 320 Pfam PF00005 ABC transporter 35 173 3.7E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS25200 75a2b5e471725554cd7fe99b844d6dcd 320 SUPERFAMILY SSF52540 14 233 8.88E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01990 11d79c31ad71490bd47846df4fedb9f6 199 SMART SM00458 58 196 2.2E-12 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS01990 11d79c31ad71490bd47846df4fedb9f6 199 Gene3D G3DSA:2.80.10.50 139 196 6.4E-9 T 06-07-2017 SMD11_RS01990 11d79c31ad71490bd47846df4fedb9f6 199 Gene3D G3DSA:2.80.10.50 70 138 1.9E-15 T 06-07-2017 SMD11_RS01990 11d79c31ad71490bd47846df4fedb9f6 199 SUPERFAMILY SSF50370 71 196 1.66E-19 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS01990 11d79c31ad71490bd47846df4fedb9f6 199 Pfam PF00652 Ricin-type beta-trefoil lectin domain 67 193 4.9E-16 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS17575 31ce78f27d7c10dc62fdb10670a45d0d 165 SUPERFAMILY SSF53271 8 151 6.42E-27 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS17575 31ce78f27d7c10dc62fdb10670a45d0d 165 Gene3D G3DSA:3.40.50.2020 10 153 4.7E-32 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS17575 31ce78f27d7c10dc62fdb10670a45d0d 165 Pfam PF00156 Phosphoribosyl transferase domain 11 152 1.2E-24 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMD11_RS04755 d0ecfefa1790203f07f599b9e8c01068 795 Pfam PF00005 ABC transporter 507 714 1.4E-10 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS04755 d0ecfefa1790203f07f599b9e8c01068 795 SUPERFAMILY SSF52540 500 764 2.8E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04755 d0ecfefa1790203f07f599b9e8c01068 795 SUPERFAMILY SSF52540 287 459 5.23E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04755 d0ecfefa1790203f07f599b9e8c01068 795 SUPERFAMILY SSF52540 23 71 5.23E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04755 d0ecfefa1790203f07f599b9e8c01068 795 Gene3D G3DSA:1.20.1580.10 555 677 6.0E-35 T 06-07-2017 SMD11_RS04755 d0ecfefa1790203f07f599b9e8c01068 795 Gene3D G3DSA:3.40.50.300 10 70 1.2E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04755 d0ecfefa1790203f07f599b9e8c01068 795 Gene3D G3DSA:3.40.50.300 678 787 7.7E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04755 d0ecfefa1790203f07f599b9e8c01068 795 Gene3D G3DSA:3.40.50.300 367 480 1.2E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04755 d0ecfefa1790203f07f599b9e8c01068 795 Gene3D G3DSA:3.40.50.300 495 551 7.7E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04755 d0ecfefa1790203f07f599b9e8c01068 795 Gene3D G3DSA:1.20.1580.10 300 366 7.9E-28 T 06-07-2017 SMD11_RS04755 d0ecfefa1790203f07f599b9e8c01068 795 Gene3D G3DSA:1.20.1580.10 112 187 7.9E-28 T 06-07-2017 SMD11_RS04755 d0ecfefa1790203f07f599b9e8c01068 795 Gene3D G3DSA:1.10.8.280 190 292 2.7E-6 T 06-07-2017 SMD11_RS16450 4ac21c5fb1fe974e3b6a79a1e6950bc5 425 Gene3D G3DSA:3.30.930.10 104 418 4.9E-125 T 06-07-2017 SMD11_RS16450 4ac21c5fb1fe974e3b6a79a1e6950bc5 425 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 419 38.947 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD11_RS16450 4ac21c5fb1fe974e3b6a79a1e6950bc5 425 SUPERFAMILY SSF55681 131 417 1.55E-84 T 06-07-2017 SMD11_RS16450 4ac21c5fb1fe974e3b6a79a1e6950bc5 425 SUPERFAMILY SSF46589 2 111 1.83E-23 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 SMD11_RS16450 4ac21c5fb1fe974e3b6a79a1e6950bc5 425 PIRSF PIRSF001529 1 423 1.5E-140 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD11_RS16450 4ac21c5fb1fe974e3b6a79a1e6950bc5 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 3.3E-23 T 06-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD11_RS16450 4ac21c5fb1fe974e3b6a79a1e6950bc5 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 221 397 2.8E-29 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS16450 4ac21c5fb1fe974e3b6a79a1e6950bc5 425 Gene3D G3DSA:1.10.287.40 2 102 7.6E-28 T 06-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD11_RS16450 4ac21c5fb1fe974e3b6a79a1e6950bc5 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 414 4.2E-131 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD11_RS16450 4ac21c5fb1fe974e3b6a79a1e6950bc5 425 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 4.2E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD11_RS16450 4ac21c5fb1fe974e3b6a79a1e6950bc5 425 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 4.2E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD11_RS16450 4ac21c5fb1fe974e3b6a79a1e6950bc5 425 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 4.2E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD11_RS16450 4ac21c5fb1fe974e3b6a79a1e6950bc5 425 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 4.2E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD11_RS16450 4ac21c5fb1fe974e3b6a79a1e6950bc5 425 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 4.2E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SMD11_RS00400 625dd4e78d02e44faae94ae11e918c98 489 Gene3D G3DSA:1.25.40.10 107 312 2.3E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS00400 625dd4e78d02e44faae94ae11e918c98 489 SUPERFAMILY SSF48452 122 156 2.73E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS00400 625dd4e78d02e44faae94ae11e918c98 489 SUPERFAMILY SSF48452 201 312 2.73E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS12085 daf6772a5c74d62f9d75605047cae504 132 Gene3D G3DSA:3.90.79.10 2 129 1.1E-32 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS12085 daf6772a5c74d62f9d75605047cae504 132 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD11_RS12085 daf6772a5c74d62f9d75605047cae504 132 PRINTS PR00502 NUDIX hydrolase family signature 33 47 1.4E-9 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS12085 daf6772a5c74d62f9d75605047cae504 132 PRINTS PR00502 NUDIX hydrolase family signature 47 62 1.4E-9 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS12085 daf6772a5c74d62f9d75605047cae504 132 Pfam PF00293 NUDIX domain 5 111 5.6E-19 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS12085 daf6772a5c74d62f9d75605047cae504 132 SUPERFAMILY SSF55811 3 128 1.19E-30 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS17615 1f219bfacb251bec9f2b6fcc83509418 442 SUPERFAMILY SSF52540 269 410 1.19E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17615 1f219bfacb251bec9f2b6fcc83509418 442 SUPERFAMILY SSF52540 44 116 1.19E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17615 1f219bfacb251bec9f2b6fcc83509418 442 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 44 363 3.3E-32 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS17615 1f219bfacb251bec9f2b6fcc83509418 442 Gene3D G3DSA:3.40.50.300 138 167 1.2E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17615 1f219bfacb251bec9f2b6fcc83509418 442 Gene3D G3DSA:3.40.50.300 4 102 1.2E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17615 1f219bfacb251bec9f2b6fcc83509418 442 Gene3D G3DSA:3.40.50.300 205 388 1.2E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20720 517c0bc0e0e8c2800dac7187d55cfcf0 62 Pfam PF03966 Trm112p-like protein 7 49 8.4E-7 T 06-07-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 SMD11_RS20720 517c0bc0e0e8c2800dac7187d55cfcf0 62 SUPERFAMILY SSF158997 1 60 1.44E-15 T 06-07-2017 SMD11_RS20720 517c0bc0e0e8c2800dac7187d55cfcf0 62 Gene3D G3DSA:2.20.25.10 10 60 4.9E-21 T 06-07-2017 SMD11_RS25410 7f44cf78eedc5b9966d3a8217ec16e8a 375 SUPERFAMILY SSF53474 133 268 3.35E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS25410 7f44cf78eedc5b9966d3a8217ec16e8a 375 SUPERFAMILY SSF53474 306 371 3.35E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS25410 7f44cf78eedc5b9966d3a8217ec16e8a 375 Gene3D G3DSA:3.40.50.1820 136 361 3.3E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12840 b4fbc2913a5466a1dd9db5ca3993b6c6 419 Gene3D G3DSA:3.40.630.10 22 207 7.5E-86 T 06-07-2017 SMD11_RS12840 b4fbc2913a5466a1dd9db5ca3993b6c6 419 Gene3D G3DSA:3.40.630.10 327 413 7.5E-86 T 06-07-2017 SMD11_RS12840 b4fbc2913a5466a1dd9db5ca3993b6c6 419 SUPERFAMILY SSF53187 22 226 1.4E-61 T 06-07-2017 SMD11_RS12840 b4fbc2913a5466a1dd9db5ca3993b6c6 419 SUPERFAMILY SSF53187 327 413 1.4E-61 T 06-07-2017 SMD11_RS12840 b4fbc2913a5466a1dd9db5ca3993b6c6 419 PIRSF PIRSF005962 13 418 1.7E-96 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 SMD11_RS12840 b4fbc2913a5466a1dd9db5ca3993b6c6 419 Pfam PF07687 Peptidase dimerisation domain 216 308 6.8E-5 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS12840 b4fbc2913a5466a1dd9db5ca3993b6c6 419 Pfam PF01546 Peptidase family M20/M25/M40 99 412 3.8E-27 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD11_RS12840 b4fbc2913a5466a1dd9db5ca3993b6c6 419 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 26 404 1.7E-101 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 SMD11_RS12840 b4fbc2913a5466a1dd9db5ca3993b6c6 419 SUPERFAMILY SSF55031 211 328 3.14E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS12840 b4fbc2913a5466a1dd9db5ca3993b6c6 419 Gene3D G3DSA:3.30.70.360 211 326 6.8E-28 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain SMD11_RS12835 64ff5738c62c74f33b17ec990f294266 340 SUPERFAMILY SSF53822 48 292 5.23E-14 T 06-07-2017 IPR028082 Periplasmic binding protein-like I SMD11_RS12835 64ff5738c62c74f33b17ec990f294266 340 Gene3D G3DSA:3.40.50.2300 157 309 6.8E-48 T 06-07-2017 SMD11_RS12835 64ff5738c62c74f33b17ec990f294266 340 Gene3D G3DSA:3.40.50.2300 33 156 6.1E-43 T 06-07-2017 SMD11_RS12835 64ff5738c62c74f33b17ec990f294266 340 Pfam PF02608 Basic membrane protein 40 337 7.6E-59 T 06-07-2017 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 SMD11_RS08590 735cadcfd4e59fe8fd28f424620c437c 281 SMART SM00450 6 131 1.8E-26 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS08590 735cadcfd4e59fe8fd28f424620c437c 281 SMART SM00450 152 272 4.5E-12 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS08590 735cadcfd4e59fe8fd28f424620c437c 281 ProSitePatterns PS00380 Rhodanese signature 1. 38 49 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 SMD11_RS08590 735cadcfd4e59fe8fd28f424620c437c 281 SUPERFAMILY SSF52821 150 278 1.2E-27 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS08590 735cadcfd4e59fe8fd28f424620c437c 281 SUPERFAMILY SSF52821 2 147 2.49E-40 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS08590 735cadcfd4e59fe8fd28f424620c437c 281 Gene3D G3DSA:3.40.250.10 152 278 8.2E-33 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS08590 735cadcfd4e59fe8fd28f424620c437c 281 Gene3D G3DSA:3.40.250.10 1 148 4.9E-50 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS08590 735cadcfd4e59fe8fd28f424620c437c 281 Pfam PF00581 Rhodanese-like domain 17 127 3.2E-17 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS08590 735cadcfd4e59fe8fd28f424620c437c 281 Pfam PF00581 Rhodanese-like domain 163 268 3.0E-9 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS03200 ffbee7c872294a3bfbd59e7672d7d10b 330 Pfam PF00480 ROK family 19 318 1.8E-61 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS03200 ffbee7c872294a3bfbd59e7672d7d10b 330 Gene3D G3DSA:3.30.420.40 153 304 2.6E-47 T 06-07-2017 SMD11_RS03200 ffbee7c872294a3bfbd59e7672d7d10b 330 Gene3D G3DSA:3.30.420.40 17 152 2.9E-41 T 06-07-2017 SMD11_RS03200 ffbee7c872294a3bfbd59e7672d7d10b 330 SUPERFAMILY SSF53067 17 319 6.36E-64 T 06-07-2017 SMD11_RS03200 ffbee7c872294a3bfbd59e7672d7d10b 330 ProSitePatterns PS01125 ROK family signature. 150 177 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS32390 3f806ba26104649c3e45bb6f57aa588a 249 SUPERFAMILY SSF143081 2 239 2.09E-68 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) SMD11_RS32390 3f806ba26104649c3e45bb6f57aa588a 249 Gene3D G3DSA:3.90.1680.10 1 240 1.3E-74 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) SMD11_RS32390 3f806ba26104649c3e45bb6f57aa588a 249 Pfam PF02586 SOS response associated peptidase (SRAP) 1 231 3.1E-69 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) SMD11_RS27825 7dc1e005e546f64208c573eedad4dfac 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 60 4.5E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS27825 7dc1e005e546f64208c573eedad4dfac 214 Gene3D G3DSA:1.10.357.10 7 189 1.8E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS27825 7dc1e005e546f64208c573eedad4dfac 214 SUPERFAMILY SSF46689 9 78 7.7E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS27825 7dc1e005e546f64208c573eedad4dfac 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS27825 7dc1e005e546f64208c573eedad4dfac 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS08810 7be6239e5d6f5eb9767b67384216fec3 170 Pfam PF03477 ATP cone domain 47 131 7.6E-13 T 06-07-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 SMD11_RS08810 7be6239e5d6f5eb9767b67384216fec3 170 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 6.9E-45 T 06-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 SMD11_RS08810 7be6239e5d6f5eb9767b67384216fec3 170 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 75.687 T 06-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 SMD11_RS09315 0b39c8f6b6bd9c393f0fe281466fce53 481 Gene3D G3DSA:3.40.309.10 266 450 6.0E-54 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS09315 0b39c8f6b6bd9c393f0fe281466fce53 481 Gene3D G3DSA:3.40.605.10 9 265 7.0E-70 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS09315 0b39c8f6b6bd9c393f0fe281466fce53 481 Pfam PF00171 Aldehyde dehydrogenase family 16 471 3.2E-130 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS09315 0b39c8f6b6bd9c393f0fe281466fce53 481 SUPERFAMILY SSF53720 8 476 9.69E-129 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS06660 6cec13d4b80fde04615c1b40dd922668 617 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 60 595 1.5E-121 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS06660 6cec13d4b80fde04615c1b40dd922668 617 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 81 106 2.1E-68 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS06660 6cec13d4b80fde04615c1b40dd922668 617 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 155 173 2.1E-68 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS06660 6cec13d4b80fde04615c1b40dd922668 617 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 483 498 2.1E-68 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS06660 6cec13d4b80fde04615c1b40dd922668 617 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 173 192 2.1E-68 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS06660 6cec13d4b80fde04615c1b40dd922668 617 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 423 441 2.1E-68 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS06660 6cec13d4b80fde04615c1b40dd922668 617 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 447 465 2.1E-68 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS06660 6cec13d4b80fde04615c1b40dd922668 617 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 507 524 2.1E-68 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS06660 6cec13d4b80fde04615c1b40dd922668 617 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 282 298 2.1E-68 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS06660 6cec13d4b80fde04615c1b40dd922668 617 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 312 331 2.1E-68 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS06660 6cec13d4b80fde04615c1b40dd922668 617 SUPERFAMILY SSF56235 52 602 1.81E-151 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS06660 6cec13d4b80fde04615c1b40dd922668 617 Pfam PF01019 Gamma-glutamyltranspeptidase 74 600 5.4E-149 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS31805 c045c8248e8f85f65352b12bc6daec40 581 Gene3D G3DSA:3.10.170.10 230 386 1.5E-40 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS31805 c045c8248e8f85f65352b12bc6daec40 581 Pfam PF03413 Peptidase propeptide and YPEB domain 116 182 5.5E-6 T 06-07-2017 IPR025711 PepSY domain SMD11_RS31805 c045c8248e8f85f65352b12bc6daec40 581 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 231 383 2.0E-41 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS31805 c045c8248e8f85f65352b12bc6daec40 581 SUPERFAMILY SSF55486 228 569 1.06E-67 T 06-07-2017 SMD11_RS31805 c045c8248e8f85f65352b12bc6daec40 581 Gene3D G3DSA:1.10.390.10 401 569 4.2E-42 T 06-07-2017 SMD11_RS31805 c045c8248e8f85f65352b12bc6daec40 581 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 54 101 1.3E-13 T 06-07-2017 IPR011096 FTP domain SMD11_RS31805 c045c8248e8f85f65352b12bc6daec40 581 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 374 390 1.1E-6 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS31805 c045c8248e8f85f65352b12bc6daec40 581 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 471 487 1.1E-6 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS31805 c045c8248e8f85f65352b12bc6daec40 581 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 336 356 1.1E-6 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS31805 c045c8248e8f85f65352b12bc6daec40 581 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 401 569 2.2E-42 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 SMD11_RS04160 8530dd93a9d1b4ba72aa0a9208bc7e9c 731 Pfam PF13515 Fusaric acid resistance protein-like 403 524 3.6E-8 T 06-07-2017 SMD11_RS01905 a6641d8625bbb3b40e72785dcc274480 142 SUPERFAMILY SSF56214 3 119 2.75E-18 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS01905 a6641d8625bbb3b40e72785dcc274480 142 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 46 124 5.0E-7 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SMD11_RS01905 a6641d8625bbb3b40e72785dcc274480 142 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 3 101 3.3E-10 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS01905 a6641d8625bbb3b40e72785dcc274480 142 Gene3D G3DSA:3.90.470.20 3 120 2.1E-21 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS01905 a6641d8625bbb3b40e72785dcc274480 142 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 40 119 9.8E-15 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SMD11_RS01905 a6641d8625bbb3b40e72785dcc274480 142 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 1 123 16.715 T 06-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SMD11_RS26430 be6a3534f6b9a99cadd64f21cf4bd67a 535 Gene3D G3DSA:3.50.50.60 33 274 5.8E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS26430 be6a3534f6b9a99cadd64f21cf4bd67a 535 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 421 532 2.0E-13 T 06-07-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 SMD11_RS26430 be6a3534f6b9a99cadd64f21cf4bd67a 535 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 47 57 4.6E-22 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 SMD11_RS26430 be6a3534f6b9a99cadd64f21cf4bd67a 535 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 349 355 4.6E-22 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 SMD11_RS26430 be6a3534f6b9a99cadd64f21cf4bd67a 535 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 109 121 4.6E-22 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 SMD11_RS26430 be6a3534f6b9a99cadd64f21cf4bd67a 535 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 378 390 4.6E-22 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 SMD11_RS26430 be6a3534f6b9a99cadd64f21cf4bd67a 535 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 34 46 4.6E-22 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 SMD11_RS26430 be6a3534f6b9a99cadd64f21cf4bd67a 535 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 63 75 4.6E-22 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 SMD11_RS26430 be6a3534f6b9a99cadd64f21cf4bd67a 535 SUPERFAMILY SSF51905 33 330 2.29E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS26430 be6a3534f6b9a99cadd64f21cf4bd67a 535 Pfam PF01266 FAD dependent oxidoreductase 35 390 3.5E-46 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD11_RS13980 ea466fdd78ae140f2f1a0064e8c70300 314 SUPERFAMILY SSF49785 180 310 1.42E-11 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS13980 ea466fdd78ae140f2f1a0064e8c70300 314 Gene3D G3DSA:2.60.120.260 197 311 4.1E-9 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS05505 5f04608a790963fd92a086107a3f734c 167 SUPERFAMILY SSF55729 32 162 3.01E-15 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS05505 5f04608a790963fd92a086107a3f734c 167 Gene3D G3DSA:3.40.630.30 41 160 2.2E-13 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS21500 23939e06e68bb8a944e88ab5f6291e1d 358 PIRSF PIRSF002825 8 344 4.5E-47 T 06-07-2017 IPR026045 Ferric binding protein SMD11_RS21500 23939e06e68bb8a944e88ab5f6291e1d 358 Pfam PF13343 Bacterial extracellular solute-binding protein 95 344 1.4E-28 T 06-07-2017 SMD11_RS21500 23939e06e68bb8a944e88ab5f6291e1d 358 Gene3D G3DSA:3.40.190.10 144 284 1.1E-29 T 06-07-2017 SMD11_RS21500 23939e06e68bb8a944e88ab5f6291e1d 358 Gene3D G3DSA:3.40.190.10 16 140 4.3E-33 T 06-07-2017 SMD11_RS21500 23939e06e68bb8a944e88ab5f6291e1d 358 Gene3D G3DSA:3.40.190.10 285 317 4.3E-33 T 06-07-2017 SMD11_RS21500 23939e06e68bb8a944e88ab5f6291e1d 358 SUPERFAMILY SSF53850 37 352 6.79E-57 T 06-07-2017 SMD11_RS09195 ae5add48614d2bf05f11f6c520021967 533 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 4 457 1.4E-56 T 06-07-2017 IPR007795 Type VII secretion system EccB SMD11_RS09195 ae5add48614d2bf05f11f6c520021967 533 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 3 529 2.9E-82 T 06-07-2017 IPR007795 Type VII secretion system EccB SMD11_RS19265 fda79e556e3e59414129220d530b43e6 375 SMART SM01240 14 372 7.2E-31 T 06-07-2017 SMD11_RS19265 fda79e556e3e59414129220d530b43e6 375 SUPERFAMILY SSF51412 12 77 7.94E-71 T 06-07-2017 SMD11_RS19265 fda79e556e3e59414129220d530b43e6 375 SUPERFAMILY SSF51412 113 371 7.94E-71 T 06-07-2017 SMD11_RS19265 fda79e556e3e59414129220d530b43e6 375 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 15 298 1.2E-43 T 06-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 SMD11_RS19265 fda79e556e3e59414129220d530b43e6 375 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 4 367 4.4E-197 T 06-07-2017 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 SMD11_RS19265 fda79e556e3e59414129220d530b43e6 375 Gene3D G3DSA:3.20.20.70 13 371 3.8E-77 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS13745 9e61cd081fbebe8d178e3093ae033dfe 328 Pfam PF00248 Aldo/keto reductase family 15 315 8.2E-71 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS13745 9e61cd081fbebe8d178e3093ae033dfe 328 Gene3D G3DSA:3.20.20.100 1 316 1.0E-97 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS13745 9e61cd081fbebe8d178e3093ae033dfe 328 SUPERFAMILY SSF51430 1 317 2.23E-96 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS12060 929c0272675f999a9494a15d7b199305 255 SUPERFAMILY SSF46548 121 231 5.93E-18 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 SMD11_RS12060 929c0272675f999a9494a15d7b199305 255 Gene3D G3DSA:3.10.20.30 5 95 2.0E-28 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS12060 929c0272675f999a9494a15d7b199305 255 Gene3D G3DSA:1.10.1060.10 96 243 1.8E-18 T 06-07-2017 SMD11_RS12060 929c0272675f999a9494a15d7b199305 255 Pfam PF13183 4Fe-4S dicluster domain 140 221 8.3E-15 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD11_RS12060 929c0272675f999a9494a15d7b199305 255 SUPERFAMILY SSF54292 5 103 4.06E-22 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS12060 929c0272675f999a9494a15d7b199305 255 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 7 105 1.3E-24 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS12060 929c0272675f999a9494a15d7b199305 255 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 53 61 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMD11_RS12060 929c0272675f999a9494a15d7b199305 255 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 18 224 1.5E-40 T 06-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS16300 d656473e2572dcb2d1db88bea66501a6 523 SMART SM00331 301 522 6.9E-18 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS16300 d656473e2572dcb2d1db88bea66501a6 523 Gene3D G3DSA:3.30.450.40 98 229 5.2E-4 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS16300 d656473e2572dcb2d1db88bea66501a6 523 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 325 523 6.4E-36 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS22210 533a4a2274c907e1a278d4cc1b8e87b4 212 SUPERFAMILY SSF52833 10 172 1.02E-23 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS22210 533a4a2274c907e1a278d4cc1b8e87b4 212 Gene3D G3DSA:3.40.30.10 8 170 2.1E-12 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS22210 533a4a2274c907e1a278d4cc1b8e87b4 212 Pfam PF01323 DSBA-like thioredoxin domain 10 169 1.6E-7 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMD11_RS27335 c668caa5fd8924dcc96a93ceb89e6102 166 Gene3D G3DSA:1.10.260.40 3 75 4.7E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS27335 c668caa5fd8924dcc96a93ceb89e6102 166 SUPERFAMILY SSF47413 4 74 4.44E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS27335 c668caa5fd8924dcc96a93ceb89e6102 166 SMART SM00530 12 69 2.1E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS27335 c668caa5fd8924dcc96a93ceb89e6102 166 Pfam PF01381 Helix-turn-helix 13 69 1.2E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS11405 074e1081d978fcb932f23412d35042ea 272 Pfam PF02586 SOS response associated peptidase (SRAP) 1 252 4.7E-64 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) SMD11_RS11405 074e1081d978fcb932f23412d35042ea 272 SUPERFAMILY SSF143081 2 261 8.76E-63 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) SMD11_RS11405 074e1081d978fcb932f23412d35042ea 272 Gene3D G3DSA:3.90.1680.10 1 262 6.5E-71 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) SMD11_RS28325 09e83eadd61a3919b837f8913dd1f5e3 216 SUPERFAMILY SSF52540 35 206 3.49E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28325 09e83eadd61a3919b837f8913dd1f5e3 216 PRINTS PR00449 Transforming protein P21 ras signature 35 56 7.4E-6 T 06-07-2017 SMD11_RS28325 09e83eadd61a3919b837f8913dd1f5e3 216 PRINTS PR00449 Transforming protein P21 ras signature 93 115 7.4E-6 T 06-07-2017 SMD11_RS28325 09e83eadd61a3919b837f8913dd1f5e3 216 PRINTS PR00449 Transforming protein P21 ras signature 183 205 7.4E-6 T 06-07-2017 SMD11_RS28325 09e83eadd61a3919b837f8913dd1f5e3 216 Gene3D G3DSA:3.40.50.300 32 205 1.0E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS28325 09e83eadd61a3919b837f8913dd1f5e3 216 Pfam PF03029 Conserved hypothetical ATP binding protein 39 202 1.2E-22 T 06-07-2017 IPR004130 GPN-loop GTPase SMD11_RS26245 18a99df0fc8dc4640583d7b827ecf8fe 259 SUPERFAMILY SSF51735 8 252 7.96E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS26245 18a99df0fc8dc4640583d7b827ecf8fe 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 5.8E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS26245 18a99df0fc8dc4640583d7b827ecf8fe 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 5.8E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS26245 18a99df0fc8dc4640583d7b827ecf8fe 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.8E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS26245 18a99df0fc8dc4640583d7b827ecf8fe 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 5.8E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS26245 18a99df0fc8dc4640583d7b827ecf8fe 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 5.8E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS26245 18a99df0fc8dc4640583d7b827ecf8fe 259 Gene3D G3DSA:3.40.50.720 9 240 8.9E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS26245 18a99df0fc8dc4640583d7b827ecf8fe 259 Pfam PF00106 short chain dehydrogenase 9 184 1.3E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS26245 18a99df0fc8dc4640583d7b827ecf8fe 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS29310 736406736d402c20d8ca37bc36bf4c72 332 SUPERFAMILY SSF51445 57 283 1.01E-31 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS29310 736406736d402c20d8ca37bc36bf4c72 332 Gene3D G3DSA:3.20.20.80 59 278 4.2E-32 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS33625 75b2d8b6e49c29370625d2fc6a6d213f 335 SUPERFAMILY SSF51197 13 240 7.0E-33 T 06-07-2017 SMD11_RS33625 75b2d8b6e49c29370625d2fc6a6d213f 335 Gene3D G3DSA:2.60.120.650 13 223 5.3E-24 T 06-07-2017 SMD11_RS33625 75b2d8b6e49c29370625d2fc6a6d213f 335 Pfam PF08007 Cupin superfamily protein 16 240 3.2E-26 T 06-07-2017 IPR003347 JmjC domain SMD11_RS25115 d8cee93c93ea4f85edd5b32c85f7ab18 991 Pfam PF00246 Zinc carboxypeptidase 135 398 5.2E-59 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS25115 d8cee93c93ea4f85edd5b32c85f7ab18 991 Gene3D G3DSA:3.40.630.10 131 445 1.4E-75 T 06-07-2017 SMD11_RS25115 d8cee93c93ea4f85edd5b32c85f7ab18 991 SMART SM00631 126 439 8.5E-68 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS25115 d8cee93c93ea4f85edd5b32c85f7ab18 991 Pfam PF05547 Immune inhibitor A peptidase M6 749 916 7.9E-10 T 06-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMD11_RS25115 d8cee93c93ea4f85edd5b32c85f7ab18 991 SUPERFAMILY SSF53187 132 408 2.51E-66 T 06-07-2017 SMD11_RS25115 d8cee93c93ea4f85edd5b32c85f7ab18 991 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 152 164 4.2E-9 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS25115 d8cee93c93ea4f85edd5b32c85f7ab18 991 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 319 332 4.2E-9 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS25115 d8cee93c93ea4f85edd5b32c85f7ab18 991 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 265 273 4.2E-9 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS25115 d8cee93c93ea4f85edd5b32c85f7ab18 991 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 179 193 4.2E-9 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS25115 d8cee93c93ea4f85edd5b32c85f7ab18 991 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 179 201 - T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 SMD11_RS05595 de31956ea77230c8a3c437c0d2cba98b 499 Gene3D G3DSA:1.20.1250.20 281 477 3.4E-17 T 06-07-2017 SMD11_RS05595 de31956ea77230c8a3c437c0d2cba98b 499 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 32 447 2.0E-108 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS05595 de31956ea77230c8a3c437c0d2cba98b 499 Gene3D G3DSA:1.20.1250.20 30 212 9.3E-27 T 06-07-2017 SMD11_RS05595 de31956ea77230c8a3c437c0d2cba98b 499 SUPERFAMILY SSF103473 266 475 1.44E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS05595 de31956ea77230c8a3c437c0d2cba98b 499 SUPERFAMILY SSF103473 17 212 1.44E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS05595 de31956ea77230c8a3c437c0d2cba98b 499 Pfam PF07690 Major Facilitator Superfamily 35 426 2.8E-50 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS29905 26684e2b4cfa722fd677ae3651b84da0 228 Pfam PF02567 Phenazine biosynthesis-like protein 17 85 8.3E-9 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMD11_RS29905 26684e2b4cfa722fd677ae3651b84da0 228 Gene3D G3DSA:3.10.310.10 4 110 4.8E-14 T 06-07-2017 SMD11_RS29905 26684e2b4cfa722fd677ae3651b84da0 228 SUPERFAMILY SSF54506 5 214 1.9E-26 T 06-07-2017 SMD11_RS29905 26684e2b4cfa722fd677ae3651b84da0 228 Gene3D G3DSA:3.10.310.10 138 210 1.1E-5 T 06-07-2017 SMD11_RS11420 29388f2e84edffb2ecdefc20c9d0eb7b 334 Pfam PF03193 Protein of unknown function, DUF258 96 269 2.0E-42 T 06-07-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 SMD11_RS11420 29388f2e84edffb2ecdefc20c9d0eb7b 334 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 36 332 26.602 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 SMD11_RS11420 29388f2e84edffb2ecdefc20c9d0eb7b 334 SUPERFAMILY SSF52540 113 330 4.92E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11420 29388f2e84edffb2ecdefc20c9d0eb7b 334 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 71 322 1.0E-40 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 SMD11_RS11420 29388f2e84edffb2ecdefc20c9d0eb7b 334 Gene3D G3DSA:3.40.50.300 113 269 1.3E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11420 29388f2e84edffb2ecdefc20c9d0eb7b 334 Gene3D G3DSA:1.10.40.50 270 331 6.8E-13 T 06-07-2017 SMD11_RS14225 74c8935d10e7d7f683c7920de0d154ae 143 PRINTS PR00502 NUDIX hydrolase family signature 37 51 4.2E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS14225 74c8935d10e7d7f683c7920de0d154ae 143 PRINTS PR00502 NUDIX hydrolase family signature 51 66 4.2E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS14225 74c8935d10e7d7f683c7920de0d154ae 143 Pfam PF00293 NUDIX domain 9 130 6.4E-18 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS14225 74c8935d10e7d7f683c7920de0d154ae 143 SUPERFAMILY SSF55811 4 134 4.87E-25 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS14225 74c8935d10e7d7f683c7920de0d154ae 143 Gene3D G3DSA:3.90.79.10 2 133 4.6E-27 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS14225 74c8935d10e7d7f683c7920de0d154ae 143 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD11_RS33450 312344ca1360b3c6b04d6e791a4ecf78 203 SUPERFAMILY SSF55729 6 178 9.9E-46 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS33450 312344ca1360b3c6b04d6e791a4ecf78 203 Pfam PF13302 Acetyltransferase (GNAT) domain 12 154 4.7E-32 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS33450 312344ca1360b3c6b04d6e791a4ecf78 203 Gene3D G3DSA:3.40.630.30 5 184 3.3E-51 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS31885 e66256dd10a9185e08624905fe330ddd 311 SMART SM00849 58 279 3.6E-22 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS31885 e66256dd10a9185e08624905fe330ddd 311 Pfam PF00753 Metallo-beta-lactamase superfamily 59 279 1.2E-28 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS31885 e66256dd10a9185e08624905fe330ddd 311 SUPERFAMILY SSF56281 33 295 3.93E-40 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS31885 e66256dd10a9185e08624905fe330ddd 311 Gene3D G3DSA:3.60.15.10 1 299 5.1E-50 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS05295 c70c44732929896705b35ef41904642f 267 Gene3D G3DSA:3.90.190.10 16 99 8.8E-18 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like SMD11_RS05295 c70c44732929896705b35ef41904642f 267 Gene3D G3DSA:3.90.190.10 134 193 8.8E-18 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like SMD11_RS05295 c70c44732929896705b35ef41904642f 267 SUPERFAMILY SSF52799 13 265 6.93E-50 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like SMD11_RS05295 c70c44732929896705b35ef41904642f 267 Pfam PF13350 Tyrosine phosphatase family 13 265 1.9E-63 T 06-07-2017 IPR026893 Tyrosine/serine-protein phosphatase IphP-type SMD11_RS18415 6d6f1e8d9a4539c5b173b01508577fc7 485 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 425 3.0E-159 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 SMD11_RS18415 6d6f1e8d9a4539c5b173b01508577fc7 485 Gene3D G3DSA:1.20.5.570 450 485 1.7E-6 T 06-07-2017 SMD11_RS18415 6d6f1e8d9a4539c5b173b01508577fc7 485 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 8 442 3.0E-196 T 06-07-2017 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 SMD11_RS18415 6d6f1e8d9a4539c5b173b01508577fc7 485 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 450 1.8E-139 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 SMD11_RS18415 6d6f1e8d9a4539c5b173b01508577fc7 485 Gene3D G3DSA:3.40.1670.10 334 448 2.0E-38 T 06-07-2017 SMD11_RS18415 6d6f1e8d9a4539c5b173b01508577fc7 485 SUPERFAMILY SSF50475 3 319 1.37E-114 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS18415 6d6f1e8d9a4539c5b173b01508577fc7 485 SUPERFAMILY SSF143968 320 485 2.88E-55 T 06-07-2017 SMD11_RS16325 a8a6dc2edecba1bd97e81cdaa2bde5b1 60 Pfam PF01361 Tautomerase enzyme 6 57 4.0E-16 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 SMD11_RS16325 a8a6dc2edecba1bd97e81cdaa2bde5b1 60 Gene3D G3DSA:3.30.429.20 1 59 7.8E-18 T 06-07-2017 SMD11_RS16325 a8a6dc2edecba1bd97e81cdaa2bde5b1 60 SUPERFAMILY SSF55331 1 58 5.5E-14 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily SMD11_RS16840 84c0e9c7045e48b0891b1383de21d936 229 SUPERFAMILY SSF88659 123 185 7.85E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16840 84c0e9c7045e48b0891b1383de21d936 229 SUPERFAMILY SSF88946 6 114 2.16E-29 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16840 84c0e9c7045e48b0891b1383de21d936 229 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 182 2.0E-29 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16840 84c0e9c7045e48b0891b1383de21d936 229 Gene3D G3DSA:1.10.1740.10 7 116 4.3E-31 T 06-07-2017 SMD11_RS16840 84c0e9c7045e48b0891b1383de21d936 229 Pfam PF08281 Sigma-70, region 4 129 181 4.5E-17 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16840 84c0e9c7045e48b0891b1383de21d936 229 Pfam PF04542 Sigma-70 region 2 29 96 1.6E-17 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16840 84c0e9c7045e48b0891b1383de21d936 229 Gene3D G3DSA:1.10.10.10 123 185 8.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS22175 806b7284e89db2931e8942426cf88245 390 Pfam PF02342 TerD domain 5 170 2.4E-39 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS22175 806b7284e89db2931e8942426cf88245 390 Gene3D G3DSA:2.60.60.30 16 168 1.4E-31 T 06-07-2017 SMD11_RS07665 154a00283b67895ea6bc2460883c6ecc 688 Gene3D G3DSA:3.40.50.300 276 460 5.9E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07665 154a00283b67895ea6bc2460883c6ecc 688 SUPERFAMILY SSF52540 243 460 1.65E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00215 1258421b99caa3d603f62ba8b8dfe475 380 SUPERFAMILY SSF47413 126 183 1.33E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS00215 1258421b99caa3d603f62ba8b8dfe475 380 Gene3D G3DSA:1.10.260.40 125 183 4.5E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS00215 1258421b99caa3d603f62ba8b8dfe475 380 Pfam PF13560 Helix-turn-helix domain 125 184 2.7E-15 T 06-07-2017 SMD11_RS00215 1258421b99caa3d603f62ba8b8dfe475 380 SMART SM00530 129 184 2.1E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS27890 a8cf1421686b1aa24def39bf1c084f46 528 SUPERFAMILY SSF52540 253 487 1.59E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27890 a8cf1421686b1aa24def39bf1c084f46 528 Gene3D G3DSA:3.40.50.300 229 479 6.5E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08520 71174f71bd25ffb4412384740884417c 259 Pfam PF12502 Protein of unknown function (DUF3710) 53 226 6.8E-62 T 06-07-2017 IPR022183 Protein of unknown function DUF3710 SMD11_RS14995 468a32f5a3afeb3827b9abe9813e1477 121 Pfam PF01906 Putative heavy-metal-binding 15 117 6.6E-34 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 SMD11_RS14995 468a32f5a3afeb3827b9abe9813e1477 121 SUPERFAMILY SSF117782 15 117 7.85E-32 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 SMD11_RS14995 468a32f5a3afeb3827b9abe9813e1477 121 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 15 117 21.994 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 SMD11_RS14995 468a32f5a3afeb3827b9abe9813e1477 121 Gene3D G3DSA:3.30.110.70 15 117 8.3E-33 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 SMD11_RS30130 594dacbab5044fc9de844f1cc33694b7 356 SUPERFAMILY SSF53474 94 333 1.17E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30130 594dacbab5044fc9de844f1cc33694b7 356 Pfam PF00756 Putative esterase 108 338 4.6E-19 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 SMD11_RS30130 594dacbab5044fc9de844f1cc33694b7 356 Gene3D G3DSA:3.40.50.1820 91 349 8.4E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS19420 d05364c92c0bd12a2de7b5e7f08dbba5 161 SUPERFAMILY SSF50249 20 153 4.8E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS19420 d05364c92c0bd12a2de7b5e7f08dbba5 161 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 33 67 4.6E-9 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal SMD11_RS19420 d05364c92c0bd12a2de7b5e7f08dbba5 161 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 70 145 1.8E-18 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal SMD11_RS33015 08f662667b4cef7e75e1cb5926abc0a2 382 SUPERFAMILY SSF47203 231 379 2.9E-16 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS33015 08f662667b4cef7e75e1cb5926abc0a2 382 Gene3D G3DSA:2.40.110.10 125 220 4.7E-27 T 06-07-2017 SMD11_RS33015 08f662667b4cef7e75e1cb5926abc0a2 382 SUPERFAMILY SSF56645 1 227 1.96E-56 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS33015 08f662667b4cef7e75e1cb5926abc0a2 382 Gene3D G3DSA:1.20.140.10 221 379 9.4E-23 T 06-07-2017 SMD11_RS33015 08f662667b4cef7e75e1cb5926abc0a2 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 206 5.8E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS33015 08f662667b4cef7e75e1cb5926abc0a2 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 121 7.6E-21 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS33015 08f662667b4cef7e75e1cb5926abc0a2 382 Gene3D G3DSA:1.10.540.10 1 121 4.6E-21 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS33015 08f662667b4cef7e75e1cb5926abc0a2 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 376 1.9E-17 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS28770 b3222b6966c97c3d15a803172d14a537 433 Gene3D G3DSA:3.90.1150.10 341 431 1.0E-48 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS28770 b3222b6966c97c3d15a803172d14a537 433 Gene3D G3DSA:3.90.1150.10 7 69 1.0E-48 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS28770 b3222b6966c97c3d15a803172d14a537 433 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 5 433 48.59 T 06-07-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 SMD11_RS28770 b3222b6966c97c3d15a803172d14a537 433 Pfam PF00202 Aminotransferase class-III 31 426 1.7E-112 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS28770 b3222b6966c97c3d15a803172d14a537 433 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS28770 b3222b6966c97c3d15a803172d14a537 433 SUPERFAMILY SSF53383 6 429 3.37E-116 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS28770 b3222b6966c97c3d15a803172d14a537 433 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 17 429 1.1E-163 T 06-07-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 SMD11_RS28770 b3222b6966c97c3d15a803172d14a537 433 Gene3D G3DSA:3.40.640.10 70 336 3.3E-84 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS05225 af357358abcf29c754c301726c0c3dcf 367 Pfam PF00589 Phage integrase family 167 349 1.9E-21 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS05225 af357358abcf29c754c301726c0c3dcf 367 Gene3D G3DSA:1.10.443.10 153 350 1.4E-35 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS05225 af357358abcf29c754c301726c0c3dcf 367 SUPERFAMILY SSF56349 152 352 5.3E-32 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD11_RS32475 f4dac5cce369978d6d39731ba2362112 500 Gene3D G3DSA:1.20.1250.20 20 207 1.3E-27 T 06-07-2017 SMD11_RS32475 f4dac5cce369978d6d39731ba2362112 500 Gene3D G3DSA:1.20.1250.20 280 484 2.8E-13 T 06-07-2017 SMD11_RS32475 f4dac5cce369978d6d39731ba2362112 500 Pfam PF07690 Major Facilitator Superfamily 31 423 1.0E-39 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS32475 f4dac5cce369978d6d39731ba2362112 500 SUPERFAMILY SSF103473 260 483 8.63E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS32475 f4dac5cce369978d6d39731ba2362112 500 SUPERFAMILY SSF103473 15 209 8.63E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS32475 f4dac5cce369978d6d39731ba2362112 500 ProSitePatterns PS00216 Sugar transport proteins signature 1. 79 95 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS12865 11efe74b0cfe73e91a6cffd0a931f841 349 SUPERFAMILY SSF53448 3 228 2.67E-43 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS12865 11efe74b0cfe73e91a6cffd0a931f841 349 Pfam PF00535 Glycosyl transferase family 2 5 123 1.4E-31 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD11_RS12865 11efe74b0cfe73e91a6cffd0a931f841 349 Gene3D G3DSA:3.90.550.10 3 202 1.1E-41 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS11220 95c88469b66671d4ce309f6535e0c4b0 86 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 22 83 8.4E-12 T 06-07-2017 IPR001607 Zinc finger, UBP-type GO:0008270 SMD11_RS11220 95c88469b66671d4ce309f6535e0c4b0 86 SUPERFAMILY SSF57850 2 84 3.77E-25 T 06-07-2017 SMD11_RS11220 95c88469b66671d4ce309f6535e0c4b0 86 Gene3D G3DSA:3.30.40.10 2 85 4.7E-23 T 06-07-2017 IPR013083 Zinc finger, RING/FYVE/PHD-type SMD11_RS28685 0c962b26616863dc9e53d45a847cdd45 294 Gene3D G3DSA:1.10.10.10 107 166 6.8E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28685 0c962b26616863dc9e53d45a847cdd45 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 166 2.1E-19 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS28685 0c962b26616863dc9e53d45a847cdd45 294 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 10 291 3.7E-100 T 06-07-2017 IPR014303 RNA polymerase sigma-70, ECF type SMD11_RS28685 0c962b26616863dc9e53d45a847cdd45 294 Gene3D G3DSA:3.10.450.50 178 290 5.3E-12 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS28685 0c962b26616863dc9e53d45a847cdd45 294 Gene3D G3DSA:1.10.1740.10 9 76 5.2E-13 T 06-07-2017 SMD11_RS28685 0c962b26616863dc9e53d45a847cdd45 294 Pfam PF04542 Sigma-70 region 2 11 74 4.8E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS28685 0c962b26616863dc9e53d45a847cdd45 294 Pfam PF08281 Sigma-70, region 4 113 163 2.3E-14 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS28685 0c962b26616863dc9e53d45a847cdd45 294 SUPERFAMILY SSF88659 98 167 1.18E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS28685 0c962b26616863dc9e53d45a847cdd45 294 SUPERFAMILY SSF88946 11 87 5.1E-14 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS28685 0c962b26616863dc9e53d45a847cdd45 294 SUPERFAMILY SSF54427 178 290 7.83E-12 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS29925 51f402d735878ffb22c4048246f0f64d 280 Pfam PF00805 Pentapeptide repeats (8 copies) 215 250 2.6E-11 T 06-07-2017 IPR001646 Pentapeptide repeat SMD11_RS29925 51f402d735878ffb22c4048246f0f64d 280 SUPERFAMILY SSF141571 62 98 8.73E-23 T 06-07-2017 SMD11_RS29925 51f402d735878ffb22c4048246f0f64d 280 SUPERFAMILY SSF141571 177 269 8.73E-23 T 06-07-2017 SMD11_RS12890 118d6db0c8268f2d5115f645d3be42ee 507 SUPERFAMILY SSF51905 272 356 4.56E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12890 118d6db0c8268f2d5115f645d3be42ee 507 SUPERFAMILY SSF51905 3 177 4.56E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12890 118d6db0c8268f2d5115f645d3be42ee 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 352 3.7E-44 T 06-07-2017 SMD11_RS12890 118d6db0c8268f2d5115f645d3be42ee 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 336 3.7E-44 T 06-07-2017 SMD11_RS12890 118d6db0c8268f2d5115f645d3be42ee 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 3.7E-44 T 06-07-2017 SMD11_RS12890 118d6db0c8268f2d5115f645d3be42ee 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 3.7E-44 T 06-07-2017 SMD11_RS12890 118d6db0c8268f2d5115f645d3be42ee 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.7E-44 T 06-07-2017 SMD11_RS12890 118d6db0c8268f2d5115f645d3be42ee 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 3.7E-44 T 06-07-2017 SMD11_RS12890 118d6db0c8268f2d5115f645d3be42ee 507 SUPERFAMILY SSF52833 394 499 1.01E-5 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS12890 118d6db0c8268f2d5115f645d3be42ee 507 Gene3D G3DSA:3.30.9.10 333 356 1.7E-9 T 06-07-2017 SMD11_RS12890 118d6db0c8268f2d5115f645d3be42ee 507 Gene3D G3DSA:3.30.9.10 168 278 1.7E-9 T 06-07-2017 SMD11_RS12890 118d6db0c8268f2d5115f645d3be42ee 507 Gene3D G3DSA:3.50.50.60 3 167 6.4E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12890 118d6db0c8268f2d5115f645d3be42ee 507 Gene3D G3DSA:3.50.50.60 283 323 6.4E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12890 118d6db0c8268f2d5115f645d3be42ee 507 Pfam PF01494 FAD binding domain 2 348 5.2E-89 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS15085 1408e3b55d0651c3583cd95886955cf8 365 Gene3D G3DSA:3.40.47.10 2 199 1.3E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS15085 1408e3b55d0651c3583cd95886955cf8 365 Gene3D G3DSA:3.40.47.10 207 346 2.5E-30 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS15085 1408e3b55d0651c3583cd95886955cf8 365 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 212 341 3.9E-16 T 06-07-2017 IPR012328 Chalcone/stilbene synthase, C-terminal SMD11_RS15085 1408e3b55d0651c3583cd95886955cf8 365 PIRSF PIRSF000451 1 349 1.7E-109 T 06-07-2017 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 SMD11_RS15085 1408e3b55d0651c3583cd95886955cf8 365 SUPERFAMILY SSF53901 206 346 2.88E-33 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS15085 1408e3b55d0651c3583cd95886955cf8 365 SUPERFAMILY SSF53901 2 198 2.3E-46 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS15085 1408e3b55d0651c3583cd95886955cf8 365 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 8 197 1.1E-15 T 06-07-2017 IPR001099 Chalcone/stilbene synthase, N-terminal SMD11_RS28480 a9fe193f728c80c9288018a621b0e912 267 SUPERFAMILY SSF56371 42 198 2.49E-12 T 06-07-2017 IPR001574 Ribosome-inactivating protein GO:0017148|GO:0030598 SMD11_RS28480 a9fe193f728c80c9288018a621b0e912 267 Gene3D G3DSA:3.40.420.10 44 177 4.8E-6 T 06-07-2017 IPR016138 Ribosome-inactivating protein, subdomain 1 GO:0017148|GO:0030598 SMD11_RS28480 a9fe193f728c80c9288018a621b0e912 267 Pfam PF00161 Ribosome inactivating protein 37 199 1.1E-8 T 06-07-2017 IPR001574 Ribosome-inactivating protein GO:0017148|GO:0030598 SMD11_RS10780 7dec4f0b04d939671e571e94419ba10a 124 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 113 8.3E-26 T 06-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 SMD11_RS10780 7dec4f0b04d939671e571e94419ba10a 124 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 83 1.0E-22 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 SMD11_RS10780 7dec4f0b04d939671e571e94419ba10a 124 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 18 89 4.0E-30 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 SMD11_RS10780 7dec4f0b04d939671e571e94419ba10a 124 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 119 18.752 T 06-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 SMD11_RS10780 7dec4f0b04d939671e571e94419ba10a 124 SUPERFAMILY SSF51344 5 85 1.14E-19 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 SMD11_RS10780 7dec4f0b04d939671e571e94419ba10a 124 Gene3D G3DSA:2.60.15.10 4 90 1.2E-24 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 SMD11_RS23320 4e63f84f039a57293d7bc91c04261070 241 Pfam PF01596 O-methyltransferase 51 239 3.7E-48 T 06-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 SMD11_RS23320 4e63f84f039a57293d7bc91c04261070 241 Gene3D G3DSA:3.40.50.150 26 239 1.1E-63 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS23320 4e63f84f039a57293d7bc91c04261070 241 SUPERFAMILY SSF53335 31 239 1.35E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS23430 42479c491409e40542628814b307a840 683 Pfam PF14378 PAP2 superfamily 461 642 7.3E-49 T 06-07-2017 IPR026841 Inositolphosphotransferase Aur1/Ipt1 SMD11_RS23430 42479c491409e40542628814b307a840 683 Pfam PF09594 Protein of unknown function (DUF2029) 75 314 8.7E-35 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 SMD11_RS24005 dcd6d7c2ad4d8191549fcd09cd514c4b 390 Pfam PF00656 Caspase domain 11 220 2.0E-12 T 06-07-2017 SMD11_RS24005 dcd6d7c2ad4d8191549fcd09cd514c4b 390 Gene3D G3DSA:3.40.50.1460 8 148 2.4E-5 T 06-07-2017 IPR029030 Caspase-like domain SMD11_RS24005 dcd6d7c2ad4d8191549fcd09cd514c4b 390 SUPERFAMILY SSF52129 8 220 5.23E-10 T 06-07-2017 IPR029030 Caspase-like domain SMD11_RS09200 ebcddbd6224e3020ed882b47d8585d4f 427 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 219 326 1.5E-29 T 06-07-2017 IPR021368 Type VII secretion system protein EccE SMD11_RS09200 ebcddbd6224e3020ed882b47d8585d4f 427 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 35 427 9.1E-63 T 06-07-2017 IPR021368 Type VII secretion system protein EccE SMD11_RS11440 7bcad3e3d5720dce5282cb67978758b8 327 SUPERFAMILY SSF161098 93 161 3.53E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11440 7bcad3e3d5720dce5282cb67978758b8 327 SUPERFAMILY SSF161098 189 308 3.53E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11440 7bcad3e3d5720dce5282cb67978758b8 327 Gene3D G3DSA:1.10.3720.10 92 322 1.4E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11440 7bcad3e3d5720dce5282cb67978758b8 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 325 3.0E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS27580 d3d3557fde93689af1fabb10c358f15f 349 SUPERFAMILY SSF48576 59 317 3.74E-32 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS27580 d3d3557fde93689af1fabb10c358f15f 349 Gene3D G3DSA:1.10.600.10 32 284 1.5E-36 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS31410 ee67bd46e3b12f9af745a8d698b5c97c 387 Pfam PF02515 CoA-transferase family III 6 363 2.5E-94 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 SMD11_RS31410 ee67bd46e3b12f9af745a8d698b5c97c 387 SUPERFAMILY SSF89796 2 386 1.83E-104 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS31410 ee67bd46e3b12f9af745a8d698b5c97c 387 Gene3D G3DSA:3.40.50.10540 299 386 1.5E-97 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS31410 ee67bd46e3b12f9af745a8d698b5c97c 387 Gene3D G3DSA:3.40.50.10540 2 214 1.5E-97 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS31410 ee67bd46e3b12f9af745a8d698b5c97c 387 Gene3D G3DSA:3.30.1540.10 228 298 7.5E-9 T 06-07-2017 SMD11_RS22935 e831726fe476ead2ddffe4f998c99edb 383 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 108 126 - T 06-07-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 SMD11_RS22935 e831726fe476ead2ddffe4f998c99edb 383 PIRSF PIRSF006621 12 345 6.7E-101 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SMD11_RS22935 e831726fe476ead2ddffe4f998c99edb 383 SUPERFAMILY SSF51395 21 332 2.75E-79 T 06-07-2017 SMD11_RS22935 e831726fe476ead2ddffe4f998c99edb 383 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 14 333 8.3E-112 T 06-07-2017 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 SMD11_RS22935 e831726fe476ead2ddffe4f998c99edb 383 Pfam PF01207 Dihydrouridine synthase (Dus) 24 330 1.2E-92 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SMD11_RS22935 e831726fe476ead2ddffe4f998c99edb 383 Gene3D G3DSA:3.20.20.70 19 259 4.6E-83 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS22935 e831726fe476ead2ddffe4f998c99edb 383 Gene3D G3DSA:1.10.1200.80 267 337 2.4E-18 T 06-07-2017 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 SMD11_RS19170 04c1b2bec5e535511a78834da8e8a3e7 185 Gene3D G3DSA:3.40.50.300 23 178 1.7E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19170 04c1b2bec5e535511a78834da8e8a3e7 185 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 28 150 3.3E-29 T 06-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 SMD11_RS19170 04c1b2bec5e535511a78834da8e8a3e7 185 SUPERFAMILY SSF52540 44 132 2.92E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19170 04c1b2bec5e535511a78834da8e8a3e7 185 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 29 152 1.7E-24 T 06-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 SMD11_RS10475 209fd0433c3034964a1ae34c16100ce1 297 SUPERFAMILY SSF48452 135 270 3.0E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS10475 209fd0433c3034964a1ae34c16100ce1 297 SMART SM01043 133 271 3.7E-21 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS10475 209fd0433c3034964a1ae34c16100ce1 297 Gene3D G3DSA:1.25.40.10 191 250 2.6E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS10475 209fd0433c3034964a1ae34c16100ce1 297 Pfam PF03704 Bacterial transcriptional activator domain 138 266 6.7E-20 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain SMD11_RS06540 b498fabdfa5dcaa98f89839fca47c7c8 192 Gene3D G3DSA:1.10.357.10 69 191 2.0E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS06540 b498fabdfa5dcaa98f89839fca47c7c8 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.9E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS06540 b498fabdfa5dcaa98f89839fca47c7c8 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.9E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS06540 b498fabdfa5dcaa98f89839fca47c7c8 192 SUPERFAMILY SSF46689 1 75 1.59E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS06540 b498fabdfa5dcaa98f89839fca47c7c8 192 SUPERFAMILY SSF48498 79 191 5.69E-25 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS06540 b498fabdfa5dcaa98f89839fca47c7c8 192 Gene3D G3DSA:1.10.10.60 1 64 2.1E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS06540 b498fabdfa5dcaa98f89839fca47c7c8 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 7.5E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS21770 9996d418189cfda1fb412d1837e43a4d 326 Pfam PF00491 Arginase family 43 313 2.0E-91 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 SMD11_RS21770 9996d418189cfda1fb412d1837e43a4d 326 PRINTS PR00116 Arginase signature 129 144 7.8E-15 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 SMD11_RS21770 9996d418189cfda1fb412d1837e43a4d 326 PRINTS PR00116 Arginase signature 242 271 7.8E-15 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 SMD11_RS21770 9996d418189cfda1fb412d1837e43a4d 326 ProSitePatterns PS01053 Arginase family signature. 245 266 - T 06-07-2017 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 SMD11_RS21770 9996d418189cfda1fb412d1837e43a4d 326 Gene3D G3DSA:3.40.800.10 17 319 1.3E-117 T 06-07-2017 IPR023696 Ureohydrolase domain SMD11_RS21770 9996d418189cfda1fb412d1837e43a4d 326 TIGRFAM TIGR01230 agmatinase: agmatinase 42 314 2.8E-70 T 06-07-2017 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 SMD11_RS21770 9996d418189cfda1fb412d1837e43a4d 326 SUPERFAMILY SSF52768 22 317 9.18E-99 T 06-07-2017 SMD11_RS21770 9996d418189cfda1fb412d1837e43a4d 326 PIRSF PIRSF036979 19 321 7.8E-110 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 SMD11_RS28580 95bc3e5a9c0f8bf6e8fde6df058969d2 150 Pfam PF07883 Cupin domain 22 80 1.2E-10 T 06-07-2017 IPR013096 Cupin 2, conserved barrel SMD11_RS28580 95bc3e5a9c0f8bf6e8fde6df058969d2 150 Gene3D G3DSA:2.60.120.10 11 89 1.1E-15 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS28580 95bc3e5a9c0f8bf6e8fde6df058969d2 150 SUPERFAMILY SSF51182 14 90 2.54E-16 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS10270 41a22f5019c5a160be6c499b5d09b1ba 252 Pfam PF14581 SseB protein C-terminal domain 121 225 1.1E-18 T 06-07-2017 IPR027945 SseB protein, C-terminal SMD11_RS30630 f28c22dfc6d29452321c6438dca3bb1a 196 SUPERFAMILY SSF46689 9 81 4.77E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS30630 f28c22dfc6d29452321c6438dca3bb1a 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 7.9E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS30630 f28c22dfc6d29452321c6438dca3bb1a 196 Gene3D G3DSA:1.10.357.10 45 189 1.9E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS30630 f28c22dfc6d29452321c6438dca3bb1a 196 Gene3D G3DSA:1.10.10.60 3 44 4.8E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS30555 662c120c2c9618cc51b941c36de58a58 92 SUPERFAMILY SSF46894 21 88 6.8E-16 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS30555 662c120c2c9618cc51b941c36de58a58 92 SMART SM00421 27 82 9.8E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS30555 662c120c2c9618cc51b941c36de58a58 92 Pfam PF00196 Bacterial regulatory proteins, luxR family 29 82 6.1E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS30555 662c120c2c9618cc51b941c36de58a58 92 Gene3D G3DSA:1.10.10.10 19 87 1.4E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33215 29e83aa3da7dd3dc78f7bc72946dc8ed 383 Gene3D G3DSA:3.40.50.300 159 239 2.7E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS33215 29e83aa3da7dd3dc78f7bc72946dc8ed 383 SUPERFAMILY SSF53795 161 215 5.49E-9 T 06-07-2017 SMD11_RS33215 29e83aa3da7dd3dc78f7bc72946dc8ed 383 SUPERFAMILY SSF52540 91 199 8.05E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10790 2e0bf75c2c640977fe429d4897f31d21 305 Gene3D G3DSA:3.40.1380.10 64 196 7.5E-38 T 06-07-2017 SMD11_RS10790 2e0bf75c2c640977fe429d4897f31d21 305 Gene3D G3DSA:1.10.287.80 212 245 1.0E-29 T 06-07-2017 SMD11_RS10790 2e0bf75c2c640977fe429d4897f31d21 305 Gene3D G3DSA:1.10.287.80 20 61 1.0E-29 T 06-07-2017 SMD11_RS10790 2e0bf75c2c640977fe429d4897f31d21 305 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 1.6E-31 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 SMD11_RS10790 2e0bf75c2c640977fe429d4897f31d21 305 PRINTS PR00126 ATP synthase gamma subunit signature 171 188 1.6E-31 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 SMD11_RS10790 2e0bf75c2c640977fe429d4897f31d21 305 PRINTS PR00126 ATP synthase gamma subunit signature 244 263 1.6E-31 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 SMD11_RS10790 2e0bf75c2c640977fe429d4897f31d21 305 PRINTS PR00126 ATP synthase gamma subunit signature 275 296 1.6E-31 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 SMD11_RS10790 2e0bf75c2c640977fe429d4897f31d21 305 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 297 33.427 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 SMD11_RS10790 2e0bf75c2c640977fe429d4897f31d21 305 Gene3D G3DSA:1.10.287.80 246 292 2.1E-27 T 06-07-2017 SMD11_RS10790 2e0bf75c2c640977fe429d4897f31d21 305 Pfam PF00231 ATP synthase 5 297 1.1E-85 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 SMD11_RS10790 2e0bf75c2c640977fe429d4897f31d21 305 SUPERFAMILY SSF52943 3 297 9.03E-81 T 06-07-2017 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 SMD11_RS10790 2e0bf75c2c640977fe429d4897f31d21 305 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 297 1.3E-93 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 SMD11_RS27320 571ff652ce1c14d5c589ca10cea80c08 368 SUPERFAMILY SSF53092 5 137 5.76E-19 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal SMD11_RS27320 571ff652ce1c14d5c589ca10cea80c08 368 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 138 1.8E-12 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 SMD11_RS27320 571ff652ce1c14d5c589ca10cea80c08 368 Gene3D G3DSA:3.40.350.10 3 136 1.3E-13 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SMD11_RS27320 571ff652ce1c14d5c589ca10cea80c08 368 SUPERFAMILY SSF55920 137 366 3.27E-56 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS27320 571ff652ce1c14d5c589ca10cea80c08 368 Pfam PF00557 Metallopeptidase family M24 146 348 1.0E-43 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS27320 571ff652ce1c14d5c589ca10cea80c08 368 Gene3D G3DSA:3.90.230.10 138 365 2.3E-55 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS26775 7f56100376e42c61644aa28fe9d285ef 124 Pfam PF01479 S4 domain 8 54 1.0E-12 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 SMD11_RS26775 7f56100376e42c61644aa28fe9d285ef 124 Gene3D G3DSA:3.10.290.10 8 98 7.7E-31 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 SMD11_RS26775 7f56100376e42c61644aa28fe9d285ef 124 SMART SM00363 8 75 2.5E-9 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 SMD11_RS26775 7f56100376e42c61644aa28fe9d285ef 124 SUPERFAMILY SSF55174 8 90 6.41E-24 T 06-07-2017 SMD11_RS26775 7f56100376e42c61644aa28fe9d285ef 124 PIRSF PIRSF016821 5 124 1.1E-45 T 06-07-2017 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 SMD11_RS33415 99e65dcbe2b602c17f4867e66d2aaae5 266 SUPERFAMILY SSF53335 43 235 1.05E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS33415 99e65dcbe2b602c17f4867e66d2aaae5 266 Gene3D G3DSA:3.40.50.150 18 230 1.1E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS33415 99e65dcbe2b602c17f4867e66d2aaae5 266 Pfam PF13649 Methyltransferase domain 58 156 4.7E-19 T 06-07-2017 SMD11_RS22275 ba79d821d304aa3e62aad9928c46d236 172 Pfam PF13328 HD domain 17 91 1.2E-8 T 06-07-2017 IPR003607 HD/PDEase domain SMD11_RS22275 ba79d821d304aa3e62aad9928c46d236 172 SUPERFAMILY SSF109604 13 151 4.08E-25 T 06-07-2017 SMD11_RS10895 8d246a2a73660eddf7ac4d5cd06edb17 184 Gene3D G3DSA:3.40.50.2300 41 160 2.5E-37 T 06-07-2017 SMD11_RS10895 8d246a2a73660eddf7ac4d5cd06edb17 184 SUPERFAMILY SSF52172 41 159 4.55E-35 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS10895 8d246a2a73660eddf7ac4d5cd06edb17 184 Pfam PF00072 Response regulator receiver domain 42 152 3.7E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS10895 8d246a2a73660eddf7ac4d5cd06edb17 184 SMART SM00448 40 152 4.5E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS02970 a48cb86450217bbaef0135ee4fc99bd2 384 Gene3D G3DSA:3.90.1150.10 246 380 4.4E-11 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS02970 a48cb86450217bbaef0135ee4fc99bd2 384 Gene3D G3DSA:3.40.640.10 91 245 2.0E-13 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS02970 a48cb86450217bbaef0135ee4fc99bd2 384 SUPERFAMILY SSF53383 50 381 5.04E-32 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS02970 a48cb86450217bbaef0135ee4fc99bd2 384 Pfam PF00155 Aminotransferase class I and II 82 367 3.8E-13 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS11210 07573633ee05af2b19724ae0fd9d4153 345 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 38 322 1.9E-21 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS11210 07573633ee05af2b19724ae0fd9d4153 345 PIRSF PIRSF006278 19 329 6.3E-82 T 06-07-2017 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase SMD11_RS11210 07573633ee05af2b19724ae0fd9d4153 345 SUPERFAMILY SSF53686 38 322 3.74E-52 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS11210 07573633ee05af2b19724ae0fd9d4153 345 Gene3D G3DSA:3.40.50.1100 122 323 1.0E-40 T 06-07-2017 SMD11_RS13345 f2fadf58c273d0ebcf7d0bea10d383ed 314 Pfam PF00561 alpha/beta hydrolase fold 24 270 5.9E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS13345 f2fadf58c273d0ebcf7d0bea10d383ed 314 Gene3D G3DSA:3.40.50.1820 3 286 3.7E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS13345 f2fadf58c273d0ebcf7d0bea10d383ed 314 SUPERFAMILY SSF53474 4 286 1.65E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12330 0c42ea311e272e895b5a5e02b6a64f9c 447 Gene3D G3DSA:3.40.50.300 184 395 5.5E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12330 0c42ea311e272e895b5a5e02b6a64f9c 447 Gene3D G3DSA:3.30.450.90 83 180 4.7E-39 T 06-07-2017 SMD11_RS12330 0c42ea311e272e895b5a5e02b6a64f9c 447 Pfam PF00437 Type II/IV secretion system protein 86 362 5.6E-89 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SMD11_RS12330 0c42ea311e272e895b5a5e02b6a64f9c 447 SUPERFAMILY SSF52540 67 397 4.69E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17075 c9d74485313d5d306e7bbc2a1e002001 111 Pfam PF01381 Helix-turn-helix 32 78 5.0E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS17075 c9d74485313d5d306e7bbc2a1e002001 111 Gene3D G3DSA:1.10.260.40 33 88 2.2E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS17075 c9d74485313d5d306e7bbc2a1e002001 111 SMART SM00530 27 82 1.9E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS17075 c9d74485313d5d306e7bbc2a1e002001 111 SUPERFAMILY SSF47413 27 87 1.42E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS30980 9d3055d26347fed325092fbd13489a7f 496 Pfam PF00270 DEAD/DEAH box helicase 93 260 1.1E-42 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD11_RS30980 9d3055d26347fed325092fbd13489a7f 496 SMART SM00487 88 288 1.8E-48 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS30980 9d3055d26347fed325092fbd13489a7f 496 SUPERFAMILY SSF52540 140 422 1.14E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30980 9d3055d26347fed325092fbd13489a7f 496 Pfam PF00271 Helicase conserved C-terminal domain 301 403 7.9E-25 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS30980 9d3055d26347fed325092fbd13489a7f 496 Gene3D G3DSA:3.40.50.300 65 277 6.6E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30980 9d3055d26347fed325092fbd13489a7f 496 Gene3D G3DSA:3.40.50.300 278 428 2.6E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30980 9d3055d26347fed325092fbd13489a7f 496 SMART SM00490 322 403 1.7E-29 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS05630 d18ed523ef82bd92cd7298f0928a1658 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS05630 d18ed523ef82bd92cd7298f0928a1658 261 Gene3D G3DSA:3.40.50.720 7 258 2.0E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05630 d18ed523ef82bd92cd7298f0928a1658 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 3.2E-47 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05630 d18ed523ef82bd92cd7298f0928a1658 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.2E-47 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05630 d18ed523ef82bd92cd7298f0928a1658 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.2E-47 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05630 d18ed523ef82bd92cd7298f0928a1658 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.2E-47 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05630 d18ed523ef82bd92cd7298f0928a1658 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.2E-47 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05630 d18ed523ef82bd92cd7298f0928a1658 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.2E-47 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05630 d18ed523ef82bd92cd7298f0928a1658 261 SUPERFAMILY SSF51735 8 258 1.61E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05630 d18ed523ef82bd92cd7298f0928a1658 261 Pfam PF00106 short chain dehydrogenase 8 202 5.4E-64 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05630 d18ed523ef82bd92cd7298f0928a1658 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.8E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05630 d18ed523ef82bd92cd7298f0928a1658 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.8E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS05630 d18ed523ef82bd92cd7298f0928a1658 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.8E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06435 765a2a59de7a0c1202135e5a45e83d12 173 SUPERFAMILY SSF50475 12 160 1.82E-39 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS06435 765a2a59de7a0c1202135e5a45e83d12 173 SMART SM00903 17 160 5.7E-43 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS06435 765a2a59de7a0c1202135e5a45e83d12 173 Pfam PF01613 Flavin reductase like domain 18 161 3.3E-33 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS06435 765a2a59de7a0c1202135e5a45e83d12 173 Gene3D G3DSA:2.30.110.10 7 159 7.3E-46 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS28170 7c64a28d70c67b0020b8a73b2d2c9e29 287 SMART SM00240 209 260 2.1E-13 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS28170 7c64a28d70c67b0020b8a73b2d2c9e29 287 Pfam PF00498 FHA domain 211 274 6.3E-19 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS28170 7c64a28d70c67b0020b8a73b2d2c9e29 287 Pfam PF13240 zinc-ribbon domain 115 136 7.9E-7 T 06-07-2017 IPR026870 Zinc-ribbon domain SMD11_RS28170 7c64a28d70c67b0020b8a73b2d2c9e29 287 SUPERFAMILY SSF49879 169 281 3.06E-31 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 SMD11_RS28170 7c64a28d70c67b0020b8a73b2d2c9e29 287 Gene3D G3DSA:2.60.200.20 188 281 6.2E-29 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS22170 1c543e1d00de7ba435cdafa040394bc2 855 Pfam PF01433 Peptidase family M1 83 389 1.6E-74 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS22170 1c543e1d00de7ba435cdafa040394bc2 855 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 849 0.0 T 06-07-2017 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 SMD11_RS22170 1c543e1d00de7ba435cdafa040394bc2 855 SUPERFAMILY SSF55486 206 456 1.2E-76 T 06-07-2017 SMD11_RS22170 1c543e1d00de7ba435cdafa040394bc2 855 Pfam PF11838 ERAP1-like C-terminal domain 534 843 5.4E-60 T 06-07-2017 IPR024571 ERAP1-like C-terminal domain SMD11_RS22170 1c543e1d00de7ba435cdafa040394bc2 855 SUPERFAMILY SSF63737 5 195 3.66E-39 T 06-07-2017 SMD11_RS22170 1c543e1d00de7ba435cdafa040394bc2 855 Gene3D G3DSA:1.10.390.10 308 457 1.1E-41 T 06-07-2017 SMD11_RS22170 1c543e1d00de7ba435cdafa040394bc2 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 134 149 1.6E-21 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS22170 1c543e1d00de7ba435cdafa040394bc2 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 295 310 1.6E-21 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS22170 1c543e1d00de7ba435cdafa040394bc2 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 178 193 1.6E-21 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS22170 1c543e1d00de7ba435cdafa040394bc2 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 314 326 1.6E-21 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS22170 1c543e1d00de7ba435cdafa040394bc2 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 261 271 1.6E-21 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 SUPERFAMILY SSF82866 236 439 1.44E-30 T 06-07-2017 SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 31 432 7.5E-108 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 3 446 35.331 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 Pfam PF02355 Protein export membrane protein 260 432 2.2E-11 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 Pfam PF02355 Protein export membrane protein 560 750 2.8E-56 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 469 753 25.535 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 Gene3D G3DSA:1.20.1640.10 546 753 2.6E-20 T 06-07-2017 SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 Gene3D G3DSA:1.20.1640.10 243 444 6.4E-24 T 06-07-2017 SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 495 741 1.2E-58 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 176 426 1.5E-58 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 Pfam PF07549 SecD/SecF GG Motif 25 45 6.0E-5 T 06-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 Pfam PF07549 SecD/SecF GG Motif 490 511 8.0E-4 T 06-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 SUPERFAMILY SSF82866 530 753 1.83E-31 T 06-07-2017 SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 PRINTS PR01755 Bacterial translocase SecF protein signature 602 616 5.5E-17 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 PRINTS PR01755 Bacterial translocase SecF protein signature 650 668 5.5E-17 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD11_RS00325 3ef6c81451fc92bbad3a751911fe3db8 772 PRINTS PR01755 Bacterial translocase SecF protein signature 493 508 5.5E-17 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD11_RS02895 35fcc7d2dbc7c7a607e25ef3641e7b0a 159 Gene3D G3DSA:3.90.79.10 11 137 2.5E-28 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS02895 35fcc7d2dbc7c7a607e25ef3641e7b0a 159 SUPERFAMILY SSF55811 15 135 3.79E-31 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS02895 35fcc7d2dbc7c7a607e25ef3641e7b0a 159 Pfam PF00293 NUDIX domain 22 133 3.6E-19 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS22715 37c8f6e7511afc5a44b144bd579bf4e5 517 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 88 219 6.4E-9 T 06-07-2017 SMD11_RS08925 32557389cbed1855069aed92c7e584b5 290 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 62 153 1.8E-19 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMD11_RS08925 32557389cbed1855069aed92c7e584b5 290 Gene3D G3DSA:1.10.3720.10 60 266 9.1E-44 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS08925 32557389cbed1855069aed92c7e584b5 290 SUPERFAMILY SSF161098 61 244 5.89E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS08925 32557389cbed1855069aed92c7e584b5 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 265 1.0E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS14475 ed1e13a631615ed4620d412f68c0ec61 197 Gene3D G3DSA:3.40.50.360 7 188 1.6E-47 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS14475 ed1e13a631615ed4620d412f68c0ec61 197 SUPERFAMILY SSF52218 7 170 3.87E-39 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS14475 ed1e13a631615ed4620d412f68c0ec61 197 Pfam PF03358 NADPH-dependent FMN reductase 7 146 4.1E-40 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMD11_RS08530 18657ba79d4b0a2f8232e99e7d7b72e2 194 SUPERFAMILY SSF54637 21 159 7.93E-30 T 06-07-2017 IPR029069 HotDog domain SMD11_RS08530 18657ba79d4b0a2f8232e99e7d7b72e2 194 Gene3D G3DSA:3.10.129.10 21 166 3.9E-41 T 06-07-2017 IPR029069 HotDog domain SMD11_RS08530 18657ba79d4b0a2f8232e99e7d7b72e2 194 Pfam PF03061 Thioesterase superfamily 75 144 3.3E-7 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 SMD11_RS17750 08ff891477c6764acf4b4261bb22b6fa 137 PIRSF PIRSF017349 1 137 1.1E-66 T 06-07-2017 IPR014487 Protein of unknown function DUF3151 SMD11_RS17750 08ff891477c6764acf4b4261bb22b6fa 137 Pfam PF11349 Protein of unknown function (DUF3151) 10 134 1.3E-58 T 06-07-2017 IPR014487 Protein of unknown function DUF3151 SMD11_RS07765 389e27df80a848a8f395a0006abf5319 150 SUPERFAMILY SSF54637 3 124 1.72E-17 T 06-07-2017 IPR029069 HotDog domain SMD11_RS07765 389e27df80a848a8f395a0006abf5319 150 Gene3D G3DSA:3.10.129.10 3 121 6.6E-17 T 06-07-2017 IPR029069 HotDog domain SMD11_RS07765 389e27df80a848a8f395a0006abf5319 150 Pfam PF07977 FabA-like domain 3 117 5.4E-6 T 06-07-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 SMD11_RS05535 5f3eaf6e7badc7c84676368dfe604aca 168 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 SMD11_RS05535 5f3eaf6e7badc7c84676368dfe604aca 168 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 159 30.544 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 SMD11_RS05535 5f3eaf6e7badc7c84676368dfe604aca 168 Pfam PF00719 Inorganic pyrophosphatase 5 157 1.0E-49 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 SMD11_RS05535 5f3eaf6e7badc7c84676368dfe604aca 168 SUPERFAMILY SSF50324 3 157 7.06E-53 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 SMD11_RS05535 5f3eaf6e7badc7c84676368dfe604aca 168 Gene3D G3DSA:3.90.80.10 2 157 3.4E-50 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 SMD11_RS13080 8474cfea7b56675b2683c7373e02341f 116 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.6E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS13080 8474cfea7b56675b2683c7373e02341f 116 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.6E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS13080 8474cfea7b56675b2683c7373e02341f 116 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 5.6E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS13080 8474cfea7b56675b2683c7373e02341f 116 Gene3D G3DSA:1.10.1660.10 1 114 5.5E-31 T 06-07-2017 SMD11_RS13080 8474cfea7b56675b2683c7373e02341f 116 Pfam PF13411 MerR HTH family regulatory protein 1 67 6.2E-19 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS13080 8474cfea7b56675b2683c7373e02341f 116 SMART SM00422 1 69 2.2E-19 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS13080 8474cfea7b56675b2683c7373e02341f 116 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS13080 8474cfea7b56675b2683c7373e02341f 116 SUPERFAMILY SSF46955 1 111 6.59E-27 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS31185 a2b4da7f77af14156d67ca4bc0e9d5b2 151 Gene3D G3DSA:3.40.630.30 14 111 1.1E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS31185 a2b4da7f77af14156d67ca4bc0e9d5b2 151 Pfam PF00583 Acetyltransferase (GNAT) family 28 104 3.6E-7 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS31185 a2b4da7f77af14156d67ca4bc0e9d5b2 151 SUPERFAMILY SSF55729 18 111 1.21E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS33755 9724254704a3a111d0565b2116dd4ffb 797 Gene3D G3DSA:1.10.510.10 125 298 5.7E-34 T 06-07-2017 SMD11_RS33755 9724254704a3a111d0565b2116dd4ffb 797 Pfam PF00069 Protein kinase domain 123 295 3.9E-23 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS33755 9724254704a3a111d0565b2116dd4ffb 797 SMART SM00220 43 306 3.3E-12 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS33755 9724254704a3a111d0565b2116dd4ffb 797 SUPERFAMILY SSF56112 100 308 2.6E-38 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS33755 9724254704a3a111d0565b2116dd4ffb 797 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 161 173 - T 06-07-2017 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS06265 e3e68452fb6f839c6361424cf23adc4e 414 Pfam PF08448 PAS fold 78 175 9.3E-7 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS06265 e3e68452fb6f839c6361424cf23adc4e 414 Gene3D G3DSA:3.30.450.20 68 180 1.5E-9 T 06-07-2017 SMD11_RS06265 e3e68452fb6f839c6361424cf23adc4e 414 Gene3D G3DSA:3.30.450.40 242 411 3.4E-8 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS06265 e3e68452fb6f839c6361424cf23adc4e 414 SUPERFAMILY SSF55781 309 412 5.23E-5 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS06265 e3e68452fb6f839c6361424cf23adc4e 414 SUPERFAMILY SSF55781 244 278 5.23E-5 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS06265 e3e68452fb6f839c6361424cf23adc4e 414 SUPERFAMILY SSF55785 70 165 5.68E-8 T 06-07-2017 IPR000014 PAS domain SMD11_RS01975 9acfdb9efde1106a34c489b196c84e55 524 Gene3D G3DSA:3.50.50.60 172 246 7.9E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01975 9acfdb9efde1106a34c489b196c84e55 524 Gene3D G3DSA:3.50.50.60 32 123 7.9E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01975 9acfdb9efde1106a34c489b196c84e55 524 Gene3D G3DSA:3.50.50.60 343 402 7.9E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01975 9acfdb9efde1106a34c489b196c84e55 524 SUPERFAMILY SSF51905 343 411 1.05E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01975 9acfdb9efde1106a34c489b196c84e55 524 SUPERFAMILY SSF51905 33 254 1.05E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01975 9acfdb9efde1106a34c489b196c84e55 524 Pfam PF00355 Rieske [2Fe-2S] domain 430 510 3.2E-16 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS01975 9acfdb9efde1106a34c489b196c84e55 524 SUPERFAMILY SSF50022 428 513 2.23E-26 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS01975 9acfdb9efde1106a34c489b196c84e55 524 Gene3D G3DSA:2.102.10.10 431 511 3.7E-29 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS01975 9acfdb9efde1106a34c489b196c84e55 524 PRINTS PR00162 Rieske 2Fe-2S subunit signature 464 475 9.7E-8 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD11_RS01975 9acfdb9efde1106a34c489b196c84e55 524 PRINTS PR00162 Rieske 2Fe-2S subunit signature 485 497 9.7E-8 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD11_RS01975 9acfdb9efde1106a34c489b196c84e55 524 PRINTS PR00162 Rieske 2Fe-2S subunit signature 497 509 9.7E-8 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD11_RS01975 9acfdb9efde1106a34c489b196c84e55 524 Pfam PF01266 FAD dependent oxidoreductase 34 382 1.9E-48 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD11_RS09965 22f2131e738688787f249f4ba7aab77f 538 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 91 190 1.3E-14 T 06-07-2017 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 SMD11_RS09965 22f2131e738688787f249f4ba7aab77f 538 Pfam PF00149 Calcineurin-like phosphoesterase 205 413 7.4E-11 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 SMD11_RS09965 22f2131e738688787f249f4ba7aab77f 538 SUPERFAMILY SSF56300 203 534 1.06E-44 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS09965 22f2131e738688787f249f4ba7aab77f 538 Gene3D G3DSA:3.60.21.10 202 537 1.3E-66 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS09965 22f2131e738688787f249f4ba7aab77f 538 SUPERFAMILY SSF49363 85 190 9.29E-14 T 06-07-2017 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 SMD11_RS09965 22f2131e738688787f249f4ba7aab77f 538 Gene3D G3DSA:2.60.40.380 91 198 3.2E-11 T 06-07-2017 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 SMD11_RS01595 604700f5c7cf358a44a26a6571f7854e 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 5.8E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS01595 604700f5c7cf358a44a26a6571f7854e 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 5.8E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS01595 604700f5c7cf358a44a26a6571f7854e 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 5.8E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS01595 604700f5c7cf358a44a26a6571f7854e 102 SUPERFAMILY SSF46785 6 89 4.86E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01595 604700f5c7cf358a44a26a6571f7854e 102 SMART SM00418 8 86 2.2E-27 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS01595 604700f5c7cf358a44a26a6571f7854e 102 Gene3D G3DSA:1.10.10.10 8 90 2.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01595 604700f5c7cf358a44a26a6571f7854e 102 Pfam PF01022 Bacterial regulatory protein, arsR family 15 61 1.3E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS14010 54a7b764594f59647259e01455a3c36e 386 Gene3D G3DSA:3.40.50.720 2 145 4.5E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS14010 54a7b764594f59647259e01455a3c36e 386 Gene3D G3DSA:3.30.360.10 146 367 3.7E-20 T 06-07-2017 SMD11_RS14010 54a7b764594f59647259e01455a3c36e 386 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 127 1.2E-19 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD11_RS14010 54a7b764594f59647259e01455a3c36e 386 SUPERFAMILY SSF51735 3 162 6.47E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS14010 54a7b764594f59647259e01455a3c36e 386 SUPERFAMILY SSF55347 135 275 9.81E-15 T 06-07-2017 SMD11_RS14010 54a7b764594f59647259e01455a3c36e 386 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 258 1.6E-4 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SMD11_RS28445 8eb17f1e6a1ae54052eafbdf9d123217 263 SUPERFAMILY SSF53335 9 218 1.27E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS28445 8eb17f1e6a1ae54052eafbdf9d123217 263 Gene3D G3DSA:3.40.50.150 3 248 4.3E-67 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS20090 6370e15ca4c96c59dbfc9b69aeb76b4a 536 Pfam PF01757 Acyltransferase family 22 358 7.2E-16 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 SMD11_RS26440 c98903e4bb8604d96199f43f67ef3d12 380 Pfam PF09754 PAC2 family 19 240 2.4E-51 T 06-07-2017 IPR019151 Proteasome assembly chaperone 2 SMD11_RS26440 c98903e4bb8604d96199f43f67ef3d12 380 SUPERFAMILY SSF159659 3 264 8.63E-87 T 06-07-2017 SMD11_RS13575 6464fa23515c4c39627996b33641c8f4 301 Gene3D G3DSA:3.40.50.1820 11 296 1.4E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS13575 6464fa23515c4c39627996b33641c8f4 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 88 2.6E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS13575 6464fa23515c4c39627996b33641c8f4 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 2.6E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS13575 6464fa23515c4c39627996b33641c8f4 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 242 256 2.6E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS13575 6464fa23515c4c39627996b33641c8f4 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 132 145 2.6E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS13575 6464fa23515c4c39627996b33641c8f4 301 Pfam PF00561 alpha/beta hydrolase fold 48 155 2.8E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS13575 6464fa23515c4c39627996b33641c8f4 301 SUPERFAMILY SSF53474 43 296 2.52E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30770 7781754b4b937a02414f5799d25ed40f 298 Pfam PF00561 alpha/beta hydrolase fold 38 139 1.8E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS30770 7781754b4b937a02414f5799d25ed40f 298 Gene3D G3DSA:3.40.50.1820 12 288 4.5E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30770 7781754b4b937a02414f5799d25ed40f 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 3.8E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS30770 7781754b4b937a02414f5799d25ed40f 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 3.8E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS30770 7781754b4b937a02414f5799d25ed40f 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 61 76 3.8E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS30770 7781754b4b937a02414f5799d25ed40f 298 SUPERFAMILY SSF53474 15 287 1.12E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS21135 599f7a4d9ecefeb23609449348ee6447 306 SUPERFAMILY SSF161098 94 280 2.22E-35 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21135 599f7a4d9ecefeb23609449348ee6447 306 Gene3D G3DSA:1.10.3720.10 84 281 7.9E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21135 599f7a4d9ecefeb23609449348ee6447 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 281 9.0E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS03990 eed074f09d7c57ddbd23eb2815ea44d2 473 Pfam PF13520 Amino acid permease 32 437 2.0E-55 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS03990 eed074f09d7c57ddbd23eb2815ea44d2 473 PIRSF PIRSF006060 13 471 9.7E-89 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS17930 8aaa6049c1f5dc496286a99e3d953bc3 266 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 24 162 1.1E-15 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD11_RS17930 8aaa6049c1f5dc496286a99e3d953bc3 266 Gene3D G3DSA:1.20.120.450 17 117 1.1E-8 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase SMD11_RS17930 8aaa6049c1f5dc496286a99e3d953bc3 266 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 22 237 2.1E-21 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD11_RS17930 8aaa6049c1f5dc496286a99e3d953bc3 266 SUPERFAMILY SSF109854 15 167 8.42E-18 T 06-07-2017 SMD11_RS17930 8aaa6049c1f5dc496286a99e3d953bc3 266 Pfam PF07398 MDMPI C-terminal domain 175 259 3.7E-7 T 06-07-2017 IPR010872 MDMPI C-terminal SMD11_RS10065 fee15e55475586d9972868d266a4f89d 174 SUPERFAMILY SSF55021 3 75 8.51E-22 T 06-07-2017 SMD11_RS10065 fee15e55475586d9972868d266a4f89d 174 Gene3D G3DSA:3.30.70.260 1 79 1.6E-33 T 06-07-2017 SMD11_RS10065 fee15e55475586d9972868d266a4f89d 174 Pfam PF13710 ACT domain 13 74 6.9E-16 T 06-07-2017 SMD11_RS10065 fee15e55475586d9972868d266a4f89d 174 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 2.1E-60 T 06-07-2017 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 SMD11_RS10065 fee15e55475586d9972868d266a4f89d 174 Pfam PF10369 Small subunit of acetolactate synthase 85 158 7.1E-28 T 06-07-2017 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 SMD11_RS10065 fee15e55475586d9972868d266a4f89d 174 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 77 4.0E-34 T 06-07-2017 SMD11_RS10065 fee15e55475586d9972868d266a4f89d 174 SUPERFAMILY SSF55021 80 161 7.5E-26 T 06-07-2017 SMD11_RS10065 fee15e55475586d9972868d266a4f89d 174 Gene3D G3DSA:3.30.70.1150 84 163 2.2E-30 T 06-07-2017 SMD11_RS31940 028e0995503ab5b1ab13e0d6a5429cc7 57 Pfam PF13602 Zinc-binding dehydrogenase 9 37 5.6E-8 T 06-07-2017 SMD11_RS08410 40012b909942ec8b35f605e6b77b4cba 471 TIGRFAM TIGR00876 tal_mycobact: transaldolase 97 444 3.6E-78 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS08410 40012b909942ec8b35f605e6b77b4cba 471 SUPERFAMILY SSF51569 97 446 1.47E-39 T 06-07-2017 SMD11_RS08410 40012b909942ec8b35f605e6b77b4cba 471 Gene3D G3DSA:3.20.20.70 91 446 4.3E-75 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS08410 40012b909942ec8b35f605e6b77b4cba 471 Hamap MF_00493 Transaldolase [tal]. 91 456 94.764 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS08410 40012b909942ec8b35f605e6b77b4cba 471 Pfam PF00923 Transaldolase 115 445 1.7E-38 T 06-07-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 SMD11_RS27585 dab0c8b5e4a3e83882f39220c519b600 513 SUPERFAMILY SSF48264 70 508 6.16E-102 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27585 dab0c8b5e4a3e83882f39220c519b600 513 Gene3D G3DSA:1.10.630.10 72 509 2.5E-106 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27585 dab0c8b5e4a3e83882f39220c519b600 513 Pfam PF00067 Cytochrome P450 74 490 6.1E-75 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27585 dab0c8b5e4a3e83882f39220c519b600 513 PRINTS PR00385 P450 superfamily signature 448 457 6.3E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27585 dab0c8b5e4a3e83882f39220c519b600 513 PRINTS PR00385 P450 superfamily signature 322 339 6.3E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27585 dab0c8b5e4a3e83882f39220c519b600 513 PRINTS PR00385 P450 superfamily signature 374 385 6.3E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27585 dab0c8b5e4a3e83882f39220c519b600 513 PRINTS PR00385 P450 superfamily signature 457 468 6.3E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27585 dab0c8b5e4a3e83882f39220c519b600 513 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 450 459 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS27585 dab0c8b5e4a3e83882f39220c519b600 513 PRINTS PR00465 E-class P450 group IV signature 417 435 6.0E-16 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27585 dab0c8b5e4a3e83882f39220c519b600 513 PRINTS PR00465 E-class P450 group IV signature 73 90 6.0E-16 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27585 dab0c8b5e4a3e83882f39220c519b600 513 PRINTS PR00465 E-class P450 group IV signature 369 385 6.0E-16 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27585 dab0c8b5e4a3e83882f39220c519b600 513 PRINTS PR00465 E-class P450 group IV signature 313 339 6.0E-16 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27585 dab0c8b5e4a3e83882f39220c519b600 513 PRINTS PR00465 E-class P450 group IV signature 441 457 6.0E-16 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27585 dab0c8b5e4a3e83882f39220c519b600 513 PRINTS PR00465 E-class P450 group IV signature 457 475 6.0E-16 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27585 dab0c8b5e4a3e83882f39220c519b600 513 PRINTS PR00465 E-class P450 group IV signature 401 415 6.0E-16 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS16700 67930c3610ae9c7d0c3b1d25467fb99d 469 Pfam PF00144 Beta-lactamase 38 335 4.5E-66 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS16700 67930c3610ae9c7d0c3b1d25467fb99d 469 SUPERFAMILY SSF56601 21 346 3.86E-77 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS16700 67930c3610ae9c7d0c3b1d25467fb99d 469 Gene3D G3DSA:3.40.710.10 38 351 9.4E-80 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS15345 fcbd4e4721b21780d9b3e26c7f1a98c2 281 SUPERFAMILY SSF56784 12 229 1.37E-30 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS15345 fcbd4e4721b21780d9b3e26c7f1a98c2 281 Gene3D G3DSA:3.40.50.1000 86 235 6.9E-48 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS15345 fcbd4e4721b21780d9b3e26c7f1a98c2 281 Pfam PF12710 haloacid dehalogenase-like hydrolase 15 200 2.4E-32 T 06-07-2017 SMD11_RS15345 fcbd4e4721b21780d9b3e26c7f1a98c2 281 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 14 201 6.3E-21 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 SMD11_RS15345 fcbd4e4721b21780d9b3e26c7f1a98c2 281 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 14 213 3.0E-61 T 06-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial SMD11_RS22655 d883d66e8fdc1d65673ebd6cc6a34f63 135 Pfam PF01337 Barstar (barnase inhibitor) 16 98 4.8E-22 T 06-07-2017 IPR000468 Barstar (barnase inhibitor) SMD11_RS22655 d883d66e8fdc1d65673ebd6cc6a34f63 135 Gene3D G3DSA:3.30.370.10 17 98 1.2E-15 T 06-07-2017 IPR000468 Barstar (barnase inhibitor) SMD11_RS22655 d883d66e8fdc1d65673ebd6cc6a34f63 135 SUPERFAMILY SSF52038 16 98 2.62E-16 T 06-07-2017 IPR000468 Barstar (barnase inhibitor) SMD11_RS10300 d0d1f9ebdeba26d0c95a708bd4ec384d 460 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 457 1.2E-209 T 06-07-2017 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 SMD11_RS10300 d0d1f9ebdeba26d0c95a708bd4ec384d 460 Pfam PF03315 Serine dehydratase beta chain 4 162 6.8E-59 T 06-07-2017 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 SMD11_RS10300 d0d1f9ebdeba26d0c95a708bd4ec384d 460 Pfam PF03313 Serine dehydratase alpha chain 193 454 4.7E-105 T 06-07-2017 IPR005130 Serine dehydratase-like, alpha subunit SMD11_RS10300 d0d1f9ebdeba26d0c95a708bd4ec384d 460 SUPERFAMILY SSF143548 17 164 6.28E-45 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SMD11_RS10300 d0d1f9ebdeba26d0c95a708bd4ec384d 460 Gene3D G3DSA:3.30.1330.90 11 164 8.5E-55 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SMD11_RS24110 7f64ad489f10f1066e7cc5118477deb5 348 Gene3D G3DSA:1.10.1610.10 7 72 7.3E-15 T 06-07-2017 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD11_RS24110 7f64ad489f10f1066e7cc5118477deb5 348 Gene3D G3DSA:3.40.50.10210 73 335 6.1E-83 T 06-07-2017 SMD11_RS24110 7f64ad489f10f1066e7cc5118477deb5 348 SUPERFAMILY SSF52733 8 344 1.09E-82 T 06-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD11_RS24110 7f64ad489f10f1066e7cc5118477deb5 348 Pfam PF02277 Phosphoribosyltransferase 13 344 6.6E-97 T 06-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 SMD11_RS13155 83d82e0fbcc9db3e49805f8de8c5e001 647 SUPERFAMILY SSF161098 453 635 9.29E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS13155 83d82e0fbcc9db3e49805f8de8c5e001 647 SUPERFAMILY SSF161098 137 319 3.27E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS13155 83d82e0fbcc9db3e49805f8de8c5e001 647 Gene3D G3DSA:1.10.3720.10 136 316 3.3E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS13155 83d82e0fbcc9db3e49805f8de8c5e001 647 Gene3D G3DSA:1.10.3720.10 452 631 5.9E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS13155 83d82e0fbcc9db3e49805f8de8c5e001 647 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 159 317 1.9E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS13155 83d82e0fbcc9db3e49805f8de8c5e001 647 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 471 628 1.3E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS25960 439bb077f8f35f9d5bd84b84c2e98ecb 399 SUPERFAMILY SSF47203 246 395 1.13E-39 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS25960 439bb077f8f35f9d5bd84b84c2e98ecb 399 Gene3D G3DSA:1.20.140.10 234 395 1.1E-39 T 06-07-2017 SMD11_RS25960 439bb077f8f35f9d5bd84b84c2e98ecb 399 Gene3D G3DSA:1.10.540.10 11 141 2.1E-36 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS25960 439bb077f8f35f9d5bd84b84c2e98ecb 399 SUPERFAMILY SSF56645 13 245 3.66E-77 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS25960 439bb077f8f35f9d5bd84b84c2e98ecb 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 143 233 9.2E-25 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS25960 439bb077f8f35f9d5bd84b84c2e98ecb 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 26 139 7.7E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS25960 439bb077f8f35f9d5bd84b84c2e98ecb 399 Gene3D G3DSA:2.40.110.10 142 233 2.3E-39 T 06-07-2017 SMD11_RS25960 439bb077f8f35f9d5bd84b84c2e98ecb 399 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 246 392 8.7E-29 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS21865 ff4c54fafe7bb4ad4dcf3e64e438de09 329 Gene3D G3DSA:3.40.1190.20 3 329 3.1E-102 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS21865 ff4c54fafe7bb4ad4dcf3e64e438de09 329 Pfam PF00294 pfkB family carbohydrate kinase 11 321 2.0E-49 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB SMD11_RS21865 ff4c54fafe7bb4ad4dcf3e64e438de09 329 SUPERFAMILY SSF53613 6 329 4.05E-73 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS21865 ff4c54fafe7bb4ad4dcf3e64e438de09 329 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 7 329 1.8E-111 T 06-07-2017 IPR030830 5-dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 SMD11_RS07125 be30e3c00de0573989b649e577a1f67b 206 Gene3D G3DSA:1.20.120.530 73 204 2.2E-17 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS07125 be30e3c00de0573989b649e577a1f67b 206 SMART SM00345 11 69 1.9E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS07125 be30e3c00de0573989b649e577a1f67b 206 Pfam PF07729 FCD domain 79 202 9.8E-20 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS07125 be30e3c00de0573989b649e577a1f67b 206 Gene3D G3DSA:1.10.10.10 6 70 4.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07125 be30e3c00de0573989b649e577a1f67b 206 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 69 6.2E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SMD11_RS07125 be30e3c00de0573989b649e577a1f67b 206 SMART SM00895 79 204 9.8E-13 T 06-07-2017 IPR011711 GntR, C-terminal SMD11_RS07125 be30e3c00de0573989b649e577a1f67b 206 SUPERFAMILY SSF48008 75 205 2.62E-19 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal SMD11_RS07125 be30e3c00de0573989b649e577a1f67b 206 SUPERFAMILY SSF46785 4 73 4.94E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS22380 249ca9afc6ce1d5a8e685fcadd8ae0cc 485 Pfam PF00905 Penicillin binding protein transpeptidase domain 153 477 1.3E-67 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD11_RS22380 249ca9afc6ce1d5a8e685fcadd8ae0cc 485 Gene3D G3DSA:3.90.1310.10 72 141 5.7E-7 T 06-07-2017 SMD11_RS22380 249ca9afc6ce1d5a8e685fcadd8ae0cc 485 Gene3D G3DSA:3.40.710.10 142 480 2.9E-93 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS22380 249ca9afc6ce1d5a8e685fcadd8ae0cc 485 SUPERFAMILY SSF56601 136 480 2.9E-85 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS31795 bc28a19258a6b3182b66410d661b47ea 290 SUPERFAMILY SSF47413 31 81 1.72E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS31795 bc28a19258a6b3182b66410d661b47ea 290 Gene3D G3DSA:1.10.260.40 2 82 1.3E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS31795 bc28a19258a6b3182b66410d661b47ea 290 Pfam PF13560 Helix-turn-helix domain 6 86 5.0E-19 T 06-07-2017 SMD11_RS31795 bc28a19258a6b3182b66410d661b47ea 290 SMART SM00530 10 83 1.5E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS05400 97bc2db21a58e891ecb3f95818d4914d 166 Pfam PF13581 Histidine kinase-like ATPase domain 31 133 7.1E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS05400 97bc2db21a58e891ecb3f95818d4914d 166 Gene3D G3DSA:3.30.565.10 43 156 3.6E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS05400 97bc2db21a58e891ecb3f95818d4914d 166 SUPERFAMILY SSF55874 58 155 4.19E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS20245 45d57f8004983d34fb2cef35696d3f9b 695 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 210 224 1.3E-11 T 06-07-2017 SMD11_RS20245 45d57f8004983d34fb2cef35696d3f9b 695 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 312 336 1.3E-11 T 06-07-2017 SMD11_RS20245 45d57f8004983d34fb2cef35696d3f9b 695 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 278 290 1.3E-11 T 06-07-2017 SMD11_RS20245 45d57f8004983d34fb2cef35696d3f9b 695 Gene3D G3DSA:3.40.50.150 151 367 1.3E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS20245 45d57f8004983d34fb2cef35696d3f9b 695 SUPERFAMILY SSF116734 563 687 2.18E-6 T 06-07-2017 SMD11_RS20245 45d57f8004983d34fb2cef35696d3f9b 695 Pfam PF02384 N-6 DNA Methylase 158 411 4.7E-35 T 06-07-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SMD11_RS20245 45d57f8004983d34fb2cef35696d3f9b 695 SUPERFAMILY SSF53335 158 463 9.09E-52 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS05165 a884044ba36c8f96627ee4d2f17dcbab 151 SMART SM00116 10 57 0.0028 T 06-07-2017 IPR000644 CBS domain SMD11_RS05165 a884044ba36c8f96627ee4d2f17dcbab 151 SMART SM00116 74 121 6.9E-5 T 06-07-2017 IPR000644 CBS domain SMD11_RS05165 a884044ba36c8f96627ee4d2f17dcbab 151 SUPERFAMILY SSF54631 1 118 1.05E-27 T 06-07-2017 SMD11_RS05165 a884044ba36c8f96627ee4d2f17dcbab 151 Gene3D G3DSA:3.10.580.10 1 118 5.0E-28 T 06-07-2017 SMD11_RS05165 a884044ba36c8f96627ee4d2f17dcbab 151 Pfam PF00571 CBS domain 3 53 2.9E-8 T 06-07-2017 IPR000644 CBS domain SMD11_RS05165 a884044ba36c8f96627ee4d2f17dcbab 151 Pfam PF00571 CBS domain 69 117 1.0E-9 T 06-07-2017 IPR000644 CBS domain SMD11_RS04325 b635714cce98e5cf2b5c5654c2c099d1 391 SUPERFAMILY SSF111342 23 310 1.44E-81 T 06-07-2017 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 SMD11_RS04325 b635714cce98e5cf2b5c5654c2c099d1 391 PIRSF PIRSF026782 27 387 6.9E-124 T 06-07-2017 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 SMD11_RS04325 b635714cce98e5cf2b5c5654c2c099d1 391 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 31 383 27.544 T 06-07-2017 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 SMD11_RS04325 b635714cce98e5cf2b5c5654c2c099d1 391 Pfam PF01888 CbiD 31 292 1.5E-88 T 06-07-2017 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 SMD11_RS04325 b635714cce98e5cf2b5c5654c2c099d1 391 Gene3D G3DSA:3.30.2110.10 34 207 2.4E-59 T 06-07-2017 SMD11_RS20410 e0816dd80d44403e1340c7c55768274d 260 SUPERFAMILY SSF48498 126 237 2.15E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS20410 e0816dd80d44403e1340c7c55768274d 260 Pfam PF00440 Bacterial regulatory proteins, tetR family 60 104 3.3E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS20410 e0816dd80d44403e1340c7c55768274d 260 SUPERFAMILY SSF46689 46 114 3.59E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS20410 e0816dd80d44403e1340c7c55768274d 260 Gene3D G3DSA:1.10.357.10 36 235 2.1E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS20410 e0816dd80d44403e1340c7c55768274d 260 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 59 72 5.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS20410 e0816dd80d44403e1340c7c55768274d 260 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 80 103 5.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS29900 38f618975701fef86be0c29351697989 251 Pfam PF14451 Mut7-C ubiquitin 5 82 8.3E-22 T 06-07-2017 IPR027798 Ubiquitin Mut7-C domain SMD11_RS29900 38f618975701fef86be0c29351697989 251 Pfam PF01927 Mut7-C RNAse domain 90 231 1.5E-40 T 06-07-2017 IPR002782 Mut7-C RNAse domain SMD11_RS01590 a3d50306dcc50ec6b875f2d6c1d50a4d 137 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 127 6.1E-21 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD11_RS01590 a3d50306dcc50ec6b875f2d6c1d50a4d 137 SUPERFAMILY SSF52788 4 128 3.66E-36 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD11_RS01590 a3d50306dcc50ec6b875f2d6c1d50a4d 137 Gene3D G3DSA:3.40.50.270 4 128 6.6E-40 T 06-07-2017 SMD11_RS01590 a3d50306dcc50ec6b875f2d6c1d50a4d 137 SMART SM00226 5 130 1.9E-45 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily SMD11_RS19470 b8c61283faf907e208fc2dbc1b26bdd0 584 Gene3D G3DSA:2.30.40.10 489 523 3.8E-11 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS19470 b8c61283faf907e208fc2dbc1b26bdd0 584 SUPERFAMILY SSF51338 1 61 8.35E-18 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS19470 b8c61283faf907e208fc2dbc1b26bdd0 584 SUPERFAMILY SSF51338 503 566 8.35E-18 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS19470 b8c61283faf907e208fc2dbc1b26bdd0 584 Gene3D G3DSA:3.20.20.140 76 311 1.8E-79 T 06-07-2017 SMD11_RS19470 b8c61283faf907e208fc2dbc1b26bdd0 584 Gene3D G3DSA:3.20.20.140 428 488 1.8E-79 T 06-07-2017 SMD11_RS19470 b8c61283faf907e208fc2dbc1b26bdd0 584 Gene3D G3DSA:2.30.40.10 1 75 4.4E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS19470 b8c61283faf907e208fc2dbc1b26bdd0 584 Pfam PF07969 Amidohydrolase family 52 554 6.3E-66 T 06-07-2017 IPR013108 Amidohydrolase 3 SMD11_RS19470 b8c61283faf907e208fc2dbc1b26bdd0 584 SUPERFAMILY SSF51556 62 319 1.97E-51 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS19470 b8c61283faf907e208fc2dbc1b26bdd0 584 SUPERFAMILY SSF51556 366 503 1.97E-51 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS23460 7dd06dd10239e8740fe94cfc2ca9eca4 162 Pfam PF13673 Acetyltransferase (GNAT) domain 45 125 5.1E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS23460 7dd06dd10239e8740fe94cfc2ca9eca4 162 SUPERFAMILY SSF55729 3 131 6.69E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS23460 7dd06dd10239e8740fe94cfc2ca9eca4 162 Gene3D G3DSA:3.40.630.30 3 128 2.8E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS21330 a0898c2b95cda60f5e123b391e56c66c 254 Pfam PF06182 ABC-2 family transporter protein 23 253 5.0E-58 T 06-07-2017 IPR010390 Protein of unknown function DUF990 SMD11_RS26710 8b6ec2e24d4b2110e373b560aef1a195 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.335 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SMD11_RS26710 8b6ec2e24d4b2110e373b560aef1a195 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.4E-17 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SMD11_RS26710 8b6ec2e24d4b2110e373b560aef1a195 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.4E-17 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SMD11_RS26710 8b6ec2e24d4b2110e373b560aef1a195 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.4E-17 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SMD11_RS26710 8b6ec2e24d4b2110e373b560aef1a195 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 06-07-2017 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS26710 8b6ec2e24d4b2110e373b560aef1a195 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 2.0E-26 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SMD11_RS26710 8b6ec2e24d4b2110e373b560aef1a195 64 Pfam PF01632 Ribosomal protein L35 2 62 5.4E-25 T 06-07-2017 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS26710 8b6ec2e24d4b2110e373b560aef1a195 64 SUPERFAMILY SSF143034 2 63 5.23E-22 T 06-07-2017 SMD11_RS10275 2b9491969285a75bc0398efc322dbcde 267 Pfam PF07179 SseB protein N-terminal domain 33 142 1.6E-13 T 06-07-2017 IPR009839 SseB protein N-terminal domain SMD11_RS10275 2b9491969285a75bc0398efc322dbcde 267 Pfam PF14581 SseB protein C-terminal domain 156 265 4.9E-24 T 06-07-2017 IPR027945 SseB protein, C-terminal SMD11_RS12010 e0125df548f266b4abb2d9217d4a8246 375 Pfam PF00005 ABC transporter 67 218 1.1E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS12010 e0125df548f266b4abb2d9217d4a8246 375 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 269 344 1.8E-22 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS12010 e0125df548f266b4abb2d9217d4a8246 375 SUPERFAMILY SSF52540 38 290 8.37E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12010 e0125df548f266b4abb2d9217d4a8246 375 SMART SM00382 75 268 5.1E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS12010 e0125df548f266b4abb2d9217d4a8246 375 Gene3D G3DSA:3.40.50.300 37 292 7.0E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12010 e0125df548f266b4abb2d9217d4a8246 375 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 271 337 1.5E-16 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS12010 e0125df548f266b4abb2d9217d4a8246 375 ProSitePatterns PS00211 ABC transporters family signature. 191 205 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS05385 a4ce8d7a996a745ba90693bdba1e090e 329 SUPERFAMILY SSF51735 1 322 1.76E-87 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05385 a4ce8d7a996a745ba90693bdba1e090e 329 Gene3D G3DSA:3.40.50.720 1 169 9.4E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05385 a4ce8d7a996a745ba90693bdba1e090e 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 249 7.9E-52 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 SMD11_RS05385 a4ce8d7a996a745ba90693bdba1e090e 329 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 322 3.6E-94 T 06-07-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 SMD11_RS05385 a4ce8d7a996a745ba90693bdba1e090e 329 Gene3D G3DSA:3.90.25.10 170 218 2.1E-36 T 06-07-2017 SMD11_RS05385 a4ce8d7a996a745ba90693bdba1e090e 329 Gene3D G3DSA:3.90.25.10 252 323 2.1E-36 T 06-07-2017 SMD11_RS04180 0ce8f7bf0ee2cadd3d0dc5a9f234c9ce 199 Gene3D G3DSA:3.40.109.10 16 197 1.1E-34 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS04180 0ce8f7bf0ee2cadd3d0dc5a9f234c9ce 199 SUPERFAMILY SSF55469 17 197 8.9E-36 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS04180 0ce8f7bf0ee2cadd3d0dc5a9f234c9ce 199 Pfam PF00881 Nitroreductase family 18 176 3.0E-14 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMD11_RS25800 c1e053d3615a136fa95ea77be893f154 208 Gene3D G3DSA:3.90.79.10 9 183 1.3E-45 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS25800 c1e053d3615a136fa95ea77be893f154 208 Pfam PF00293 NUDIX domain 48 161 1.2E-16 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS25800 c1e053d3615a136fa95ea77be893f154 208 SUPERFAMILY SSF55811 10 181 2.3E-41 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS01350 eacdb41570db9396b51e7afb00afdd11 333 Pfam PF12833 Helix-turn-helix domain 238 318 4.3E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS01350 eacdb41570db9396b51e7afb00afdd11 333 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 286 301 2.9E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD11_RS01350 eacdb41570db9396b51e7afb00afdd11 333 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 301 317 2.9E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SMD11_RS01350 eacdb41570db9396b51e7afb00afdd11 333 SUPERFAMILY SSF46689 267 318 1.16E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS01350 eacdb41570db9396b51e7afb00afdd11 333 Pfam PF14525 AraC-binding-like domain 23 195 2.5E-26 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD11_RS01350 eacdb41570db9396b51e7afb00afdd11 333 SMART SM00342 232 317 8.3E-26 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS01350 eacdb41570db9396b51e7afb00afdd11 333 Gene3D G3DSA:1.10.10.60 213 267 7.4E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS01350 eacdb41570db9396b51e7afb00afdd11 333 Gene3D G3DSA:1.10.10.60 268 318 5.3E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS01875 e9b640abfeba24cf94356a9c6f9deb51 471 Gene3D G3DSA:3.30.470.20 169 360 2.2E-18 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS01875 e9b640abfeba24cf94356a9c6f9deb51 471 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 175 359 6.1E-10 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SMD11_RS01875 e9b640abfeba24cf94356a9c6f9deb51 471 SUPERFAMILY SSF56059 164 375 8.31E-26 T 06-07-2017 SMD11_RS05955 11ac4614ca8ba72258d6ab63c5dc170d 185 Gene3D G3DSA:3.40.1360.10 75 180 1.6E-11 T 06-07-2017 SMD11_RS05955 11ac4614ca8ba72258d6ab63c5dc170d 185 SUPERFAMILY SSF56731 60 180 1.57E-6 T 06-07-2017 SMD11_RS00075 7f7302a96975787c9d9847b6c7bd2fd9 224 Gene3D G3DSA:2.150.10.10 59 214 5.6E-8 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal SMD11_RS00075 7f7302a96975787c9d9847b6c7bd2fd9 224 SUPERFAMILY SSF51120 58 210 4.8E-8 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal SMD11_RS01040 fd4c5ebe02f74c5990f442b45c39c174 246 Gene3D G3DSA:3.40.50.1820 21 246 1.2E-14 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01040 fd4c5ebe02f74c5990f442b45c39c174 246 SUPERFAMILY SSF53474 123 246 7.81E-16 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01040 fd4c5ebe02f74c5990f442b45c39c174 246 SUPERFAMILY SSF53474 22 89 7.81E-16 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS06880 2e8ca2bc82bd0b4b6e06031a2a0e8b20 142 Gene3D G3DSA:3.10.450.30 49 139 1.8E-41 T 06-07-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 SMD11_RS06880 2e8ca2bc82bd0b4b6e06031a2a0e8b20 142 SUPERFAMILY SSF53933 49 140 4.25E-38 T 06-07-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 SMD11_RS06880 2e8ca2bc82bd0b4b6e06031a2a0e8b20 142 Pfam PF00545 ribonuclease 57 135 4.7E-29 T 06-07-2017 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 SMD11_RS12740 b6e323ef23c108cfa88130bc074d3615 378 SUPERFAMILY SSF51556 13 351 2.81E-72 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS12740 b6e323ef23c108cfa88130bc074d3615 378 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 18 354 6.6E-73 T 06-07-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 SMD11_RS12740 b6e323ef23c108cfa88130bc074d3615 378 Gene3D G3DSA:3.20.20.140 14 356 5.0E-103 T 06-07-2017 SMD11_RS12740 b6e323ef23c108cfa88130bc074d3615 378 Pfam PF00962 Adenosine/AMP deaminase 17 354 5.9E-88 T 06-07-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 SMD11_RS12740 b6e323ef23c108cfa88130bc074d3615 378 Hamap MF_00540 Adenosine deaminase [add]. 12 357 56.067 T 06-07-2017 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 SMD11_RS07955 e7c0e25c0709617519a4b4bd97beafe1 302 SUPERFAMILY SSF82282 8 301 1.07E-77 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMD11_RS07955 e7c0e25c0709617519a4b4bd97beafe1 302 Pfam PF02574 Homocysteine S-methyltransferase 18 299 7.3E-65 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMD11_RS07955 e7c0e25c0709617519a4b4bd97beafe1 302 Gene3D G3DSA:3.20.20.330 8 301 1.4E-88 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 SMD11_RS10635 adf2db4596741475e78cae6cf8375fcb 216 Pfam PF01987 Mitochondrial biogenesis AIM24 3 211 8.3E-34 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 SMD11_RS10635 adf2db4596741475e78cae6cf8375fcb 216 Gene3D G3DSA:3.60.160.10 8 211 1.0E-43 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 SMD11_RS10635 adf2db4596741475e78cae6cf8375fcb 216 SUPERFAMILY SSF51219 1 213 7.06E-45 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMD11_RS26350 4f878c971eecf007e7420f59f7c95d6a 349 Pfam PF00296 Luciferase-like monooxygenase 17 318 1.5E-80 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS26350 4f878c971eecf007e7420f59f7c95d6a 349 SUPERFAMILY SSF51679 1 337 2.88E-71 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS26350 4f878c971eecf007e7420f59f7c95d6a 349 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 322 1.0E-122 T 06-07-2017 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c SMD11_RS26350 4f878c971eecf007e7420f59f7c95d6a 349 Gene3D G3DSA:3.20.20.30 1 336 2.8E-77 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS20640 a8069f71390f236d8bad960a901f37b4 585 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 460 553 1.4E-7 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMD11_RS20640 a8069f71390f236d8bad960a901f37b4 585 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 179 341 2.9E-37 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS20640 a8069f71390f236d8bad960a901f37b4 585 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 179 341 9.2E-41 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS31250 f5293c2605e48983bb92b82e3240adb0 148 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 127 1.7E-13 T 06-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain SMD11_RS31250 f5293c2605e48983bb92b82e3240adb0 148 SUPERFAMILY SSF55961 2 137 3.81E-22 T 06-07-2017 SMD11_RS31250 f5293c2605e48983bb92b82e3240adb0 148 Gene3D G3DSA:3.30.530.20 3 136 3.6E-7 T 06-07-2017 IPR023393 START-like domain SMD11_RS29655 18c395ff3d5653ae21d45634545298a4 337 SUPERFAMILY SSF50494 106 326 1.5E-16 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS29655 18c395ff3d5653ae21d45634545298a4 337 Gene3D G3DSA:2.40.10.10 137 209 9.4E-9 T 06-07-2017 SMD11_RS20690 6362e27fe3edcacad0dcdd89ea39923c 87 Pfam PF02467 Transcription factor WhiB 19 82 6.1E-27 T 06-07-2017 IPR003482 Transcription factor WhiB SMD11_RS20690 6362e27fe3edcacad0dcdd89ea39923c 87 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 87 18.896 T 06-07-2017 IPR003482 Transcription factor WhiB SMD11_RS30635 81b1dae899c4fccc7c61ba7f5a653a3c 142 Pfam PF12680 SnoaL-like domain 15 119 1.8E-12 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain SMD11_RS30635 81b1dae899c4fccc7c61ba7f5a653a3c 142 ProDom PD011053 BIOSYNTHESIS PHENAZINE PROBABLE PHZA PHZB ANTIBIOTIC VIRULENCE A/B EHPA PHZ1 4 136 0.002 T 06-07-2017 IPR004964 Phenazine biosynthesis protein A/B GO:0017000 SMD11_RS30635 81b1dae899c4fccc7c61ba7f5a653a3c 142 Gene3D G3DSA:3.10.450.50 4 129 4.9E-50 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS30635 81b1dae899c4fccc7c61ba7f5a653a3c 142 SUPERFAMILY SSF54427 7 129 5.73E-34 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS10510 1a85abe39998220a0076a514f6a6acd5 319 Gene3D G3DSA:1.10.10.60 268 315 4.3E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS10510 1a85abe39998220a0076a514f6a6acd5 319 SUPERFAMILY SSF46689 213 264 2.24E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS10510 1a85abe39998220a0076a514f6a6acd5 319 Gene3D G3DSA:1.10.10.60 212 267 9.9E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS10510 1a85abe39998220a0076a514f6a6acd5 319 Pfam PF12833 Helix-turn-helix domain 236 318 1.3E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS10510 1a85abe39998220a0076a514f6a6acd5 319 SMART SM00342 230 317 8.0E-26 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS10510 1a85abe39998220a0076a514f6a6acd5 319 SUPERFAMILY SSF46689 267 317 2.05E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS10510 1a85abe39998220a0076a514f6a6acd5 319 Pfam PF14525 AraC-binding-like domain 14 192 8.3E-25 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SMD11_RS20435 a1d797c376c5cd601e2ac00056931791 287 Pfam PF12811 Bax inhibitor 1 like 53 283 6.3E-74 T 06-07-2017 IPR010539 Protein of unknown function UCP009160 SMD11_RS20435 a1d797c376c5cd601e2ac00056931791 287 PIRSF PIRSF009160 1 287 5.3E-82 T 06-07-2017 IPR010539 Protein of unknown function UCP009160 SMD11_RS32625 d64f8ab60d29bd89d844081cfde2f87e 238 PIRSF PIRSF006755 2 217 2.8E-35 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 SMD11_RS32625 d64f8ab60d29bd89d844081cfde2f87e 238 Gene3D G3DSA:3.40.50.300 4 209 5.7E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS32625 d64f8ab60d29bd89d844081cfde2f87e 238 SUPERFAMILY SSF52540 4 201 3.1E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS32625 d64f8ab60d29bd89d844081cfde2f87e 238 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 5 169 1.2E-29 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 SMD11_RS32625 d64f8ab60d29bd89d844081cfde2f87e 238 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 206 23.147 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 SMD11_RS32625 d64f8ab60d29bd89d844081cfde2f87e 238 Pfam PF13500 AAA domain 4 192 2.5E-32 T 06-07-2017 SMD11_RS19800 a57d8aa93c56c6ad1a11ac6c45f52b22 380 SUPERFAMILY SSF56266 7 219 1.7E-68 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD11_RS19800 a57d8aa93c56c6ad1a11ac6c45f52b22 380 SUPERFAMILY SSF56266 246 352 1.7E-68 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD11_RS19800 a57d8aa93c56c6ad1a11ac6c45f52b22 380 Pfam PF03576 Peptidase family S58 12 353 7.9E-70 T 06-07-2017 IPR005321 Peptidase S58, DmpA SMD11_RS19800 a57d8aa93c56c6ad1a11ac6c45f52b22 380 Gene3D G3DSA:3.60.70.12 6 355 6.3E-90 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 SMD11_RS22615 f1731f328d624b5d1cf06822a374e56a 243 SUPERFAMILY SSF56281 8 239 1.96E-39 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS22615 f1731f328d624b5d1cf06822a374e56a 243 Pfam PF00753 Metallo-beta-lactamase superfamily 28 220 1.4E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS22615 f1731f328d624b5d1cf06822a374e56a 243 SMART SM00849 26 220 6.8E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS22615 f1731f328d624b5d1cf06822a374e56a 243 Gene3D G3DSA:3.60.15.10 4 239 8.3E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS11090 df7d846bc8a1c153b6448e28e5177968 403 SMART SM00919 176 396 3.8E-110 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 SMD11_RS11090 df7d846bc8a1c153b6448e28e5177968 403 Gene3D G3DSA:3.40.50.720 174 402 1.1E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS11090 df7d846bc8a1c153b6448e28e5177968 403 SUPERFAMILY SSF51735 176 402 7.17E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS11090 df7d846bc8a1c153b6448e28e5177968 403 PIRSF PIRSF000106 32 403 3.1E-75 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 SMD11_RS11090 df7d846bc8a1c153b6448e28e5177968 403 Gene3D G3DSA:3.40.50.10380 29 173 8.1E-54 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMD11_RS11090 df7d846bc8a1c153b6448e28e5177968 403 SMART SM01274 31 164 4.9E-77 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMD11_RS11090 df7d846bc8a1c153b6448e28e5177968 403 SUPERFAMILY SSF53223 26 174 3.24E-55 T 06-07-2017 SMD11_RS11090 df7d846bc8a1c153b6448e28e5177968 403 Pfam PF00390 Malic enzyme, N-terminal domain 35 164 8.4E-28 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SMD11_RS11090 df7d846bc8a1c153b6448e28e5177968 403 Pfam PF03949 Malic enzyme, NAD binding domain 178 377 3.9E-20 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 SMD11_RS29315 08020ecf294f9869b383fa3d044f9548 500 Pfam PF07690 Major Facilitator Superfamily 97 415 4.1E-15 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS29315 08020ecf294f9869b383fa3d044f9548 500 SUPERFAMILY SSF103473 65 497 1.96E-38 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS29315 08020ecf294f9869b383fa3d044f9548 500 Gene3D G3DSA:1.20.1250.20 85 263 2.0E-9 T 06-07-2017 SMD11_RS29315 08020ecf294f9869b383fa3d044f9548 500 Gene3D G3DSA:1.20.1250.20 284 489 4.4E-14 T 06-07-2017 SMD11_RS22835 b4a14e29d3fd9771baf86a11e003c4e9 150 Pfam PF13581 Histidine kinase-like ATPase domain 27 124 3.0E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS22835 b4a14e29d3fd9771baf86a11e003c4e9 150 SUPERFAMILY SSF55874 54 145 3.61E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS26630 923af8b275f48db32b3620277e277e15 377 Pfam PF03595 Voltage-dependent anion channel 15 350 1.0E-65 T 06-07-2017 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 SMD11_RS29080 8d7e9b5a5d51f201c2005bb2e226eb30 813 SUPERFAMILY SSF56235 39 205 2.52E-149 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS29080 8d7e9b5a5d51f201c2005bb2e226eb30 813 SUPERFAMILY SSF56235 242 808 2.52E-149 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS29080 8d7e9b5a5d51f201c2005bb2e226eb30 813 Gene3D G3DSA:3.60.20.10 407 635 3.3E-73 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS29080 8d7e9b5a5d51f201c2005bb2e226eb30 813 Gene3D G3DSA:3.60.20.10 183 324 3.3E-73 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS29080 8d7e9b5a5d51f201c2005bb2e226eb30 813 Pfam PF01804 Penicillin amidase 46 799 8.0E-127 T 06-07-2017 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 SMD11_RS29080 8d7e9b5a5d51f201c2005bb2e226eb30 813 Gene3D G3DSA:1.10.439.10 46 182 3.2E-31 T 06-07-2017 IPR023343 Penicillin amidase type, domain1 GO:0016811 SMD11_RS29080 8d7e9b5a5d51f201c2005bb2e226eb30 813 Gene3D G3DSA:2.30.120.10 325 382 5.7E-14 T 06-07-2017 SMD11_RS01660 ed7cd27c7fd86654479c9274ded577ba 89 SUPERFAMILY SSF49503 3 88 1.02E-25 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS01660 ed7cd27c7fd86654479c9274ded577ba 89 Pfam PF13473 Cupredoxin-like domain 8 88 5.4E-9 T 06-07-2017 IPR028096 EfeO-type cupredoxin-like domain SMD11_RS01660 ed7cd27c7fd86654479c9274ded577ba 89 Gene3D G3DSA:2.60.40.420 5 88 3.5E-27 T 06-07-2017 IPR008972 Cupredoxin SMD11_RS33425 6a095f3598e36f4dea3b4ea74816e068 327 Pfam PF16715 Cyclodipeptide synthase 74 303 9.0E-53 T 06-07-2017 IPR030903 Cyclodileucine synthase GO:0016755 SMD11_RS33425 6a095f3598e36f4dea3b4ea74816e068 327 TIGRFAM TIGR04539 tRNA_cyclodipep: tRNA-dependent cyclodipeptide synthase 74 303 2.7E-61 T 06-07-2017 IPR030903 Cyclodileucine synthase GO:0016755 SMD11_RS29090 372690fb979fdf2a5aa79cbd2308a65f 435 SUPERFAMILY SSF56801 20 425 2.22E-63 T 06-07-2017 SMD11_RS29090 372690fb979fdf2a5aa79cbd2308a65f 435 Pfam PF14535 AMP-binding enzyme C-terminal domain 337 430 8.6E-26 T 06-07-2017 IPR028154 AMP-dependent ligase, C-terminal SMD11_RS29090 372690fb979fdf2a5aa79cbd2308a65f 435 Pfam PF00501 AMP-binding enzyme 94 290 8.2E-15 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS29090 372690fb979fdf2a5aa79cbd2308a65f 435 Gene3D G3DSA:3.30.300.30 327 430 3.6E-36 T 06-07-2017 SMD11_RS29090 372690fb979fdf2a5aa79cbd2308a65f 435 Gene3D G3DSA:3.40.50.980 93 250 3.5E-12 T 06-07-2017 SMD11_RS29090 372690fb979fdf2a5aa79cbd2308a65f 435 PIRSF PIRSF006444 3 432 1.3E-199 T 06-07-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 SMD11_RS29090 372690fb979fdf2a5aa79cbd2308a65f 435 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 12 430 2.4E-208 T 06-07-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 SMD11_RS31220 5bec41949970e4c1760623af21cc9e67 480 Gene3D G3DSA:3.40.630.10 34 98 2.1E-68 T 06-07-2017 SMD11_RS31220 5bec41949970e4c1760623af21cc9e67 480 Gene3D G3DSA:3.40.630.10 241 472 2.1E-68 T 06-07-2017 SMD11_RS31220 5bec41949970e4c1760623af21cc9e67 480 Pfam PF02225 PA domain 135 216 3.5E-14 T 06-07-2017 IPR003137 PA domain SMD11_RS31220 5bec41949970e4c1760623af21cc9e67 480 SUPERFAMILY SSF52025 96 244 6.67E-16 T 06-07-2017 SMD11_RS31220 5bec41949970e4c1760623af21cc9e67 480 Gene3D G3DSA:3.50.30.30 103 230 1.1E-29 T 06-07-2017 SMD11_RS31220 5bec41949970e4c1760623af21cc9e67 480 Pfam PF04389 Peptidase family M28 242 467 1.2E-41 T 06-07-2017 IPR007484 Peptidase M28 SMD11_RS31220 5bec41949970e4c1760623af21cc9e67 480 SUPERFAMILY SSF53187 35 87 1.01E-60 T 06-07-2017 SMD11_RS31220 5bec41949970e4c1760623af21cc9e67 480 SUPERFAMILY SSF53187 226 472 1.01E-60 T 06-07-2017 SMD11_RS07535 2f57e1c7f70c1004b0e51ada1800a99e 261 SUPERFAMILY SSF52540 8 224 6.23E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07535 2f57e1c7f70c1004b0e51ada1800a99e 261 SMART SM00382 34 223 2.1E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS07535 2f57e1c7f70c1004b0e51ada1800a99e 261 Pfam PF00005 ABC transporter 25 175 2.2E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS07535 2f57e1c7f70c1004b0e51ada1800a99e 261 Gene3D G3DSA:3.40.50.300 7 223 1.6E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25045 6b8f1b79bfef6d7df3b5c826cc4220e0 347 Pfam PF03741 Integral membrane protein TerC family 69 275 6.4E-54 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 SMD11_RS25045 6b8f1b79bfef6d7df3b5c826cc4220e0 347 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 312 1.3E-116 T 06-07-2017 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 SMD11_RS27420 5a46f296a93f8ac650bc3dd98d644fe1 474 Pfam PF01029 NusB family 21 146 2.0E-25 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMD11_RS27420 5a46f296a93f8ac650bc3dd98d644fe1 474 Pfam PF01189 16S rRNA methyltransferase RsmB/F 282 471 2.4E-42 T 06-07-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD11_RS27420 5a46f296a93f8ac650bc3dd98d644fe1 474 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 286 296 4.7E-21 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD11_RS27420 5a46f296a93f8ac650bc3dd98d644fe1 474 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 352 364 4.7E-21 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD11_RS27420 5a46f296a93f8ac650bc3dd98d644fe1 474 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 402 418 4.7E-21 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD11_RS27420 5a46f296a93f8ac650bc3dd98d644fe1 474 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 253 267 4.7E-21 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD11_RS27420 5a46f296a93f8ac650bc3dd98d644fe1 474 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 455 472 4.7E-21 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD11_RS27420 5a46f296a93f8ac650bc3dd98d644fe1 474 SUPERFAMILY SSF48013 21 179 1.28E-34 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMD11_RS27420 5a46f296a93f8ac650bc3dd98d644fe1 474 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 351 362 - T 06-07-2017 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SMD11_RS27420 5a46f296a93f8ac650bc3dd98d644fe1 474 Gene3D G3DSA:1.10.940.10 17 180 2.1E-47 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SMD11_RS27420 5a46f296a93f8ac650bc3dd98d644fe1 474 Gene3D G3DSA:3.40.50.150 263 472 2.4E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS27420 5a46f296a93f8ac650bc3dd98d644fe1 474 SUPERFAMILY SSF53335 165 472 2.29E-53 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS00275 24a646afadaa454db055ea04d33fea87 318 SUPERFAMILY SSF53448 20 172 5.18E-14 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS00275 24a646afadaa454db055ea04d33fea87 318 Pfam PF13632 Glycosyl transferase family group 2 20 266 2.7E-19 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD11_RS07130 0f9efab54027eb245b399bfb590f3f7e 304 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 271 291 2.0E-5 T 06-07-2017 IPR024726 Ferric iron reductase, C-terminal GO:0051537 SMD11_RS18095 34c36e52bc5cbbca328b39f189839e04 158 SUPERFAMILY SSF52980 16 146 1.98E-37 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD11_RS18095 34c36e52bc5cbbca328b39f189839e04 158 Gene3D G3DSA:3.40.960.10 31 145 3.2E-40 T 06-07-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 SMD11_RS18095 34c36e52bc5cbbca328b39f189839e04 158 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 16 130 7.8E-40 T 06-07-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 SMD11_RS18095 34c36e52bc5cbbca328b39f189839e04 158 Pfam PF03852 DNA mismatch endonuclease Vsr 18 83 1.0E-19 T 06-07-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 SMD11_RS29085 e5cc5dee9b67a1e79f1b9e497b8f22f8 501 Gene3D G3DSA:3.30.300.30 402 499 2.3E-29 T 06-07-2017 SMD11_RS29085 e5cc5dee9b67a1e79f1b9e497b8f22f8 501 Gene3D G3DSA:3.40.50.980 6 175 2.1E-34 T 06-07-2017 SMD11_RS29085 e5cc5dee9b67a1e79f1b9e497b8f22f8 501 Pfam PF13193 AMP-binding enzyme C-terminal domain 416 489 5.3E-22 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS29085 e5cc5dee9b67a1e79f1b9e497b8f22f8 501 Pfam PF00501 AMP-binding enzyme 14 407 9.4E-100 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS29085 e5cc5dee9b67a1e79f1b9e497b8f22f8 501 Gene3D G3DSA:2.30.38.10 326 401 2.2E-26 T 06-07-2017 SMD11_RS29085 e5cc5dee9b67a1e79f1b9e497b8f22f8 501 SUPERFAMILY SSF56801 4 499 1.96E-148 T 06-07-2017 SMD11_RS29085 e5cc5dee9b67a1e79f1b9e497b8f22f8 501 Gene3D G3DSA:3.40.50.980 176 319 1.1E-37 T 06-07-2017 SMD11_RS12210 41e24f6d889b2d376627d144c54aa26b 318 SUPERFAMILY SSF117892 122 252 1.15E-7 T 06-07-2017 IPR001107 Band 7 domain SMD11_RS12210 41e24f6d889b2d376627d144c54aa26b 318 Pfam PF01145 SPFH domain / Band 7 family 90 259 2.0E-22 T 06-07-2017 IPR001107 Band 7 domain SMD11_RS12210 41e24f6d889b2d376627d144c54aa26b 318 SMART SM00244 86 250 7.0E-10 T 06-07-2017 IPR001107 Band 7 domain SMD11_RS07090 05d6cb7dce73dac3ab261913af6c4ad4 178 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 SMD11_RS07090 05d6cb7dce73dac3ab261913af6c4ad4 178 Pfam PF01799 [2Fe-2S] binding domain 74 167 1.3E-27 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD11_RS07090 05d6cb7dce73dac3ab261913af6c4ad4 178 Gene3D G3DSA:3.10.20.30 2 77 7.3E-26 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS07090 05d6cb7dce73dac3ab261913af6c4ad4 178 SUPERFAMILY SSF47741 104 174 1.96E-30 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD11_RS07090 05d6cb7dce73dac3ab261913af6c4ad4 178 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 54 1.1E-7 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS07090 05d6cb7dce73dac3ab261913af6c4ad4 178 SUPERFAMILY SSF54292 2 79 1.97E-20 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 SMD11_RS07090 05d6cb7dce73dac3ab261913af6c4ad4 178 Gene3D G3DSA:1.10.150.120 103 174 1.9E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 SMD11_RS08400 8bc9dfc9fb2987e311ea5416f6c6bd84 323 Gene3D G3DSA:3.90.1580.10 76 319 2.6E-50 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 SMD11_RS08400 8bc9dfc9fb2987e311ea5416f6c6bd84 323 Pfam PF03781 Sulfatase-modifying factor enzyme 1 74 318 9.2E-44 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 SMD11_RS08400 8bc9dfc9fb2987e311ea5416f6c6bd84 323 SUPERFAMILY SSF56436 78 319 7.77E-54 T 06-07-2017 IPR016187 C-type lectin fold SMD11_RS23690 ce23332ce3bca7b76cbdfee23bfb1003 448 SUPERFAMILY SSF54909 85 440 2.15E-92 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS23690 ce23332ce3bca7b76cbdfee23bfb1003 448 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 90 436 1.7E-103 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SMD11_RS23690 ce23332ce3bca7b76cbdfee23bfb1003 448 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 36 447 7.7E-172 T 06-07-2017 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 SMD11_RS23690 ce23332ce3bca7b76cbdfee23bfb1003 448 Pfam PF04261 Dyp-type peroxidase family 90 436 1.3E-117 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SMD11_RS05145 a299195806497c21d1b62cc07540aa0d 224 SUPERFAMILY SSF54631 2 145 8.46E-36 T 06-07-2017 SMD11_RS05145 a299195806497c21d1b62cc07540aa0d 224 Pfam PF04972 BON domain 146 213 7.9E-13 T 06-07-2017 IPR007055 BON domain SMD11_RS05145 a299195806497c21d1b62cc07540aa0d 224 PIRSF PIRSF036990 4 221 5.9E-62 T 06-07-2017 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON SMD11_RS05145 a299195806497c21d1b62cc07540aa0d 224 SMART SM00116 13 61 1.4E-9 T 06-07-2017 IPR000644 CBS domain SMD11_RS05145 a299195806497c21d1b62cc07540aa0d 224 SMART SM00116 95 143 4.4E-11 T 06-07-2017 IPR000644 CBS domain SMD11_RS05145 a299195806497c21d1b62cc07540aa0d 224 Gene3D G3DSA:3.10.580.10 5 144 3.3E-35 T 06-07-2017 SMD11_RS05145 a299195806497c21d1b62cc07540aa0d 224 Pfam PF00571 CBS domain 6 60 1.8E-14 T 06-07-2017 IPR000644 CBS domain SMD11_RS05145 a299195806497c21d1b62cc07540aa0d 224 Pfam PF00571 CBS domain 89 142 2.6E-15 T 06-07-2017 IPR000644 CBS domain SMD11_RS01075 5b2385cad03a22b19c78bac570fa0a63 51 Gene3D G3DSA:3.40.50.720 2 51 1.7E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS01075 5b2385cad03a22b19c78bac570fa0a63 51 SUPERFAMILY SSF51735 1 51 3.94E-7 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32610 a3b00c4c834460a199e1bd91916d9fda 137 SUPERFAMILY SSF54637 1 125 4.71E-34 T 06-07-2017 IPR029069 HotDog domain SMD11_RS32610 a3b00c4c834460a199e1bd91916d9fda 137 Gene3D G3DSA:3.10.129.10 1 129 6.4E-36 T 06-07-2017 IPR029069 HotDog domain SMD11_RS32610 a3b00c4c834460a199e1bd91916d9fda 137 Pfam PF13279 Thioesterase-like superfamily 1 116 1.7E-16 T 06-07-2017 SMD11_RS27450 01b4348e52a1bc0041580296d904b929 330 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 27 85 1.6E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS27450 01b4348e52a1bc0041580296d904b929 330 SUPERFAMILY SSF46785 24 102 7.07E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS27450 01b4348e52a1bc0041580296d904b929 330 Gene3D G3DSA:3.40.190.10 110 190 1.8E-22 T 06-07-2017 SMD11_RS27450 01b4348e52a1bc0041580296d904b929 330 Gene3D G3DSA:3.40.190.10 291 318 1.8E-22 T 06-07-2017 SMD11_RS27450 01b4348e52a1bc0041580296d904b929 330 Pfam PF03466 LysR substrate binding domain 132 315 8.2E-21 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS27450 01b4348e52a1bc0041580296d904b929 330 SUPERFAMILY SSF53850 110 314 3.26E-38 T 06-07-2017 SMD11_RS27450 01b4348e52a1bc0041580296d904b929 330 Gene3D G3DSA:3.40.190.10 191 287 5.8E-28 T 06-07-2017 SMD11_RS27450 01b4348e52a1bc0041580296d904b929 330 Gene3D G3DSA:1.10.10.10 23 103 5.4E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01525 2a3508847d7c82e98cccbfbba9afd116 146 Gene3D G3DSA:1.10.260.40 36 120 8.4E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS01375 46e83052e43ee8f310a07848ff406f2f 406 Pfam PF00144 Beta-lactamase 62 376 1.2E-61 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS01375 46e83052e43ee8f310a07848ff406f2f 406 SUPERFAMILY SSF56601 56 371 2.5E-79 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS01375 46e83052e43ee8f310a07848ff406f2f 406 Gene3D G3DSA:3.40.710.10 55 375 1.4E-77 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS30590 2ca882c44e0c2e72be80f5e697c20e32 258 SUPERFAMILY SSF51735 7 220 8.32E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30590 2ca882c44e0c2e72be80f5e697c20e32 258 Pfam PF13460 NAD(P)H-binding 12 152 3.0E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30590 2ca882c44e0c2e72be80f5e697c20e32 258 Gene3D G3DSA:3.40.50.720 7 201 2.5E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19020 b7ef8ecbfeb60fc83e937a79eb3381f2 134 Gene3D G3DSA:3.30.420.80 11 134 1.8E-58 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SMD11_RS19020 b7ef8ecbfeb60fc83e937a79eb3381f2 134 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 06-07-2017 IPR018102 Ribosomal S11, conserved site SMD11_RS19020 b7ef8ecbfeb60fc83e937a79eb3381f2 134 Pfam PF00411 Ribosomal protein S11 24 133 1.6E-48 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SMD11_RS19020 b7ef8ecbfeb60fc83e937a79eb3381f2 134 PIRSF PIRSF002131 4 134 2.7E-54 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SMD11_RS19020 b7ef8ecbfeb60fc83e937a79eb3381f2 134 SUPERFAMILY SSF53137 19 134 7.19E-50 T 06-07-2017 SMD11_RS19020 b7ef8ecbfeb60fc83e937a79eb3381f2 134 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 6 134 34.437 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SMD11_RS19020 b7ef8ecbfeb60fc83e937a79eb3381f2 134 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 15 131 1.7E-59 T 06-07-2017 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS32000 2a83509edb3abd6331b4083c5aa9c6a5 621 SUPERFAMILY SSF53448 161 411 4.39E-34 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS32000 2a83509edb3abd6331b4083c5aa9c6a5 621 Gene3D G3DSA:3.90.550.10 225 399 4.9E-12 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS32000 2a83509edb3abd6331b4083c5aa9c6a5 621 Pfam PF13506 Glycosyl transferase family 21 215 383 3.4E-19 T 06-07-2017 IPR025993 Ceramide glucosyltransferase GO:0016757 KEGG: 00600+2.4.1.80|MetaCyc: PWY-5129|Reactome: R-HSA-1660662 SMD11_RS29240 4411cbdef5928153a621fe19292acce0 347 Gene3D G3DSA:2.130.10.10 15 342 4.9E-41 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS29240 4411cbdef5928153a621fe19292acce0 347 SUPERFAMILY SSF51004 7 330 1.2E-49 T 06-07-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain SMD11_RS07055 81def082ec1d2474908dbd71401e69e9 262 Pfam PF02308 MgtC family 13 137 1.4E-35 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SMD11_RS07055 81def082ec1d2474908dbd71401e69e9 262 PRINTS PR01837 MgtC/SapB protein signature 33 51 1.2E-44 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SMD11_RS07055 81def082ec1d2474908dbd71401e69e9 262 PRINTS PR01837 MgtC/SapB protein signature 92 116 1.2E-44 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SMD11_RS07055 81def082ec1d2474908dbd71401e69e9 262 PRINTS PR01837 MgtC/SapB protein signature 14 33 1.2E-44 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SMD11_RS07055 81def082ec1d2474908dbd71401e69e9 262 PRINTS PR01837 MgtC/SapB protein signature 65 87 1.2E-44 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 SMD11_RS07390 fe146c053e4124c487133bd069fd03e2 138 Pfam PF03965 Penicillinase repressor 20 125 1.3E-19 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SMD11_RS07390 fe146c053e4124c487133bd069fd03e2 138 SUPERFAMILY SSF46785 21 125 4.03E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07390 fe146c053e4124c487133bd069fd03e2 138 Gene3D G3DSA:1.10.10.10 21 89 9.6E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17765 296c9ced0a14a17cf1a44fdba4b651ff 235 Pfam PF00326 Prolyl oligopeptidase family 100 217 8.8E-8 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 SMD11_RS17765 296c9ced0a14a17cf1a44fdba4b651ff 235 Gene3D G3DSA:3.40.50.1820 10 222 1.2E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS17765 296c9ced0a14a17cf1a44fdba4b651ff 235 SUPERFAMILY SSF53474 4 222 3.54E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32700 43c1ce696051ca31118074a203c078ee 474 Pfam PF13520 Amino acid permease 3 439 4.9E-53 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS32700 43c1ce696051ca31118074a203c078ee 474 PIRSF PIRSF006060 1 457 6.7E-47 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS32700 43c1ce696051ca31118074a203c078ee 474 ProSitePatterns PS00218 Amino acid permeases signature. 31 62 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD11_RS32645 c3567d2e5e8dbf3d9f8f041931b58893 391 SUPERFAMILY SSF53383 43 387 7.85E-95 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS32645 c3567d2e5e8dbf3d9f8f041931b58893 391 Gene3D G3DSA:3.90.1150.10 278 386 7.6E-16 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS32645 c3567d2e5e8dbf3d9f8f041931b58893 391 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 240 249 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 SMD11_RS32645 c3567d2e5e8dbf3d9f8f041931b58893 391 Pfam PF00155 Aminotransferase class I and II 45 385 1.9E-59 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SMD11_RS32645 c3567d2e5e8dbf3d9f8f041931b58893 391 Gene3D G3DSA:3.40.640.10 62 277 1.6E-75 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS00145 2bd0e9fcba00d842d550bda48e29b340 244 SUPERFAMILY SSF52540 12 192 1.82E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09895 14f744965e6c22b15f38c6e891a28d0d 1081 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 585 692 3.7E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS09895 14f744965e6c22b15f38c6e891a28d0d 1081 Gene3D G3DSA:3.30.565.10 549 691 6.2E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS09895 14f744965e6c22b15f38c6e891a28d0d 1081 SUPERFAMILY SSF55874 571 691 2.49E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS09895 14f744965e6c22b15f38c6e891a28d0d 1081 Pfam PF00672 HAMP domain 383 466 2.5E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS09895 14f744965e6c22b15f38c6e891a28d0d 1081 SMART SM00387 582 694 1.9E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS09895 14f744965e6c22b15f38c6e891a28d0d 1081 Pfam PF08376 Nitrate and nitrite sensing 103 361 2.2E-33 T 06-07-2017 IPR013587 Nitrate/nitrite sensing protein SMD11_RS09895 14f744965e6c22b15f38c6e891a28d0d 1081 SMART SM00304 400 470 5.6E-4 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS08825 239cd5d7d43378f571b53bb1c523cc4e 255 SUPERFAMILY SSF55729 84 249 6.9E-46 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS08825 239cd5d7d43378f571b53bb1c523cc4e 255 Gene3D G3DSA:3.40.630.30 85 249 7.7E-49 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS08825 239cd5d7d43378f571b53bb1c523cc4e 255 SMART SM01006 88 136 2.3E-14 T 06-07-2017 IPR019432 Siderophore biosynthesis protein, conserved domain SMD11_RS08825 239cd5d7d43378f571b53bb1c523cc4e 255 Pfam PF13523 Acetyltransferase (GNAT) domain 92 237 1.1E-47 T 06-07-2017 SMD11_RS00790 090c8f03883df6d72989283070f68b42 324 SUPERFAMILY SSF52777 31 222 3.78E-14 T 06-07-2017 SMD11_RS01940 7b7e3d4d39b23d38a286f928466c46b5 359 Pfam PF00355 Rieske [2Fe-2S] domain 34 118 4.2E-15 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS01940 7b7e3d4d39b23d38a286f928466c46b5 359 SUPERFAMILY SSF50022 33 141 2.36E-26 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS01940 7b7e3d4d39b23d38a286f928466c46b5 359 Gene3D G3DSA:2.102.10.10 33 149 1.5E-26 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS01940 7b7e3d4d39b23d38a286f928466c46b5 359 SUPERFAMILY SSF55961 133 347 2.36E-7 T 06-07-2017 SMD11_RS26250 b3efb5f7e62d616123858949639a99c1 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 1.1E-22 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS26250 b3efb5f7e62d616123858949639a99c1 206 Gene3D G3DSA:1.10.357.10 70 205 4.4E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS26250 b3efb5f7e62d616123858949639a99c1 206 SUPERFAMILY SSF48498 94 205 1.93E-15 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS26250 b3efb5f7e62d616123858949639a99c1 206 SUPERFAMILY SSF46689 21 96 1.15E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS26250 b3efb5f7e62d616123858949639a99c1 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 68 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD11_RS26250 b3efb5f7e62d616123858949639a99c1 206 Gene3D G3DSA:1.10.10.60 22 69 1.4E-23 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS26250 b3efb5f7e62d616123858949639a99c1 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 3.9E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS26250 b3efb5f7e62d616123858949639a99c1 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 3.9E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS16035 27794c9a6f3e22d4fb6dad4708058428 508 Pfam PF01565 FAD binding domain 39 165 7.7E-17 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD11_RS16035 27794c9a6f3e22d4fb6dad4708058428 508 Pfam PF08031 Berberine and berberine like 453 506 9.1E-14 T 06-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 SMD11_RS16035 27794c9a6f3e22d4fb6dad4708058428 508 SUPERFAMILY SSF56176 15 208 1.17E-31 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS16035 27794c9a6f3e22d4fb6dad4708058428 508 Gene3D G3DSA:3.30.465.10 94 207 3.4E-7 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS16035 27794c9a6f3e22d4fb6dad4708058428 508 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 34 67 - T 06-07-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 SMD11_RS16035 27794c9a6f3e22d4fb6dad4708058428 508 Gene3D G3DSA:3.30.43.10 28 93 3.7E-8 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS10280 e708c76d086741c5866f5f204313d7aa 240 Pfam PF13671 AAA domain 60 198 2.9E-8 T 06-07-2017 SMD11_RS10280 e708c76d086741c5866f5f204313d7aa 240 SUPERFAMILY SSF52540 52 185 1.33E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10280 e708c76d086741c5866f5f204313d7aa 240 Gene3D G3DSA:3.40.50.300 60 190 7.3E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22810 b13380d3462966f8b1b54b7b60d4bb64 352 Gene3D G3DSA:1.10.390.10 182 349 3.4E-52 T 06-07-2017 SMD11_RS22810 b13380d3462966f8b1b54b7b60d4bb64 352 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 189 200 9.4E-29 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS22810 b13380d3462966f8b1b54b7b60d4bb64 352 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 271 287 9.4E-29 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS22810 b13380d3462966f8b1b54b7b60d4bb64 352 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 168 184 9.4E-29 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS22810 b13380d3462966f8b1b54b7b60d4bb64 352 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 132 152 9.4E-29 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 SMD11_RS22810 b13380d3462966f8b1b54b7b60d4bb64 352 SUPERFAMILY SSF55486 47 349 3.48E-83 T 06-07-2017 SMD11_RS22810 b13380d3462966f8b1b54b7b60d4bb64 352 Gene3D G3DSA:3.10.170.10 55 181 2.1E-43 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS22810 b13380d3462966f8b1b54b7b60d4bb64 352 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 180 349 4.2E-52 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 SMD11_RS22810 b13380d3462966f8b1b54b7b60d4bb64 352 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 70 177 7.2E-29 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 SMD11_RS24885 a4ead4fd2469995da679efa6f33a0e1b 601 SUPERFAMILY SSF56300 45 374 3.8E-75 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS24885 a4ead4fd2469995da679efa6f33a0e1b 601 Gene3D G3DSA:3.90.780.10 375 583 7.0E-41 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS24885 a4ead4fd2469995da679efa6f33a0e1b 601 Pfam PF00149 Calcineurin-like phosphoesterase 47 294 2.0E-11 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 SMD11_RS24885 a4ead4fd2469995da679efa6f33a0e1b 601 Pfam PF02872 5'-nucleotidase, C-terminal domain 375 554 5.8E-30 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS24885 a4ead4fd2469995da679efa6f33a0e1b 601 PRINTS PR01607 Apyrase family signature 244 261 3.1E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS24885 a4ead4fd2469995da679efa6f33a0e1b 601 PRINTS PR01607 Apyrase family signature 45 63 3.1E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS24885 a4ead4fd2469995da679efa6f33a0e1b 601 PRINTS PR01607 Apyrase family signature 529 548 3.1E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS24885 a4ead4fd2469995da679efa6f33a0e1b 601 PRINTS PR01607 Apyrase family signature 277 300 3.1E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS24885 a4ead4fd2469995da679efa6f33a0e1b 601 PRINTS PR01607 Apyrase family signature 438 461 3.1E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS24885 a4ead4fd2469995da679efa6f33a0e1b 601 Gene3D G3DSA:3.60.21.10 45 374 3.0E-78 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS24885 a4ead4fd2469995da679efa6f33a0e1b 601 ProSitePatterns PS00786 5'-nucleotidase signature 2. 142 153 - T 06-07-2017 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS24885 a4ead4fd2469995da679efa6f33a0e1b 601 SUPERFAMILY SSF55816 372 587 8.89E-42 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 SMD11_RS21860 dc435aefbf34bb40f7e028581fe554e9 295 SUPERFAMILY SSF51569 28 282 4.39E-32 T 06-07-2017 SMD11_RS21860 dc435aefbf34bb40f7e028581fe554e9 295 Gene3D G3DSA:3.20.20.70 26 285 2.6E-34 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS29700 a3e59343ee0257c136f2bea84c01913e 253 Pfam PF00975 Thioesterase domain 25 248 2.5E-20 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS29700 a3e59343ee0257c136f2bea84c01913e 253 Gene3D G3DSA:3.40.50.1820 19 252 1.9E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS29700 a3e59343ee0257c136f2bea84c01913e 253 SUPERFAMILY SSF53474 18 252 2.01E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS05885 6795f805664875ecf959ebb713c6787e 391 Pfam PF13560 Helix-turn-helix domain 5 59 1.1E-9 T 06-07-2017 SMD11_RS05885 6795f805664875ecf959ebb713c6787e 391 SMART SM00530 7 63 1.6E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS05885 6795f805664875ecf959ebb713c6787e 391 SUPERFAMILY SSF47413 3 69 5.35E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS05885 6795f805664875ecf959ebb713c6787e 391 Gene3D G3DSA:1.10.260.40 3 60 3.7E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS27805 1233d9ddd85d74b8a5414966a0fc23b5 397 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 170 391 4.9E-28 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS27805 1233d9ddd85d74b8a5414966a0fc23b5 397 SMART SM00331 142 391 3.6E-19 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS12375 ccf821c97be4d8dcde2d5e876e85c8fb 134 Pfam PF01042 Endoribonuclease L-PSP 14 132 5.1E-29 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family SMD11_RS12375 ccf821c97be4d8dcde2d5e876e85c8fb 134 SUPERFAMILY SSF55298 4 133 7.07E-33 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD11_RS12375 ccf821c97be4d8dcde2d5e876e85c8fb 134 Gene3D G3DSA:3.30.1330.40 2 133 6.8E-37 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SMD11_RS30275 01b69a965872c2c77cccae58c32ea627 288 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 56 286 8.7E-31 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMD11_RS30275 01b69a965872c2c77cccae58c32ea627 288 Gene3D G3DSA:3.60.130.10 45 288 2.3E-34 T 06-07-2017 SMD11_RS30275 01b69a965872c2c77cccae58c32ea627 288 SUPERFAMILY SSF51197 49 288 7.33E-41 T 06-07-2017 SMD11_RS03740 106907cb797cfae58c5209901f274dfa 308 SUPERFAMILY SSF161098 68 297 3.53E-56 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS03740 106907cb797cfae58c5209901f274dfa 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 303 7.0E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS03740 106907cb797cfae58c5209901f274dfa 308 Gene3D G3DSA:1.20.58.370 21 56 2.7E-6 T 06-07-2017 SMD11_RS03740 106907cb797cfae58c5209901f274dfa 308 Gene3D G3DSA:1.10.3720.10 74 304 3.2E-58 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS03740 106907cb797cfae58c5209901f274dfa 308 SUPERFAMILY SSF160964 20 60 1.83E-7 T 06-07-2017 SMD11_RS18150 351c7008aae0f64233c734ac6723e2a2 182 Pfam PF12802 MarR family 55 112 2.1E-12 T 06-07-2017 SMD11_RS18150 351c7008aae0f64233c734ac6723e2a2 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 109 1.0E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS18150 351c7008aae0f64233c734ac6723e2a2 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 143 163 1.0E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS18150 351c7008aae0f64233c734ac6723e2a2 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 129 1.0E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS18150 351c7008aae0f64233c734ac6723e2a2 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 93 1.0E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS18150 351c7008aae0f64233c734ac6723e2a2 182 SMART SM00347 50 153 1.2E-19 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS18150 351c7008aae0f64233c734ac6723e2a2 182 ProSitePatterns PS00519 AsnC-type HTH domain signature. 78 104 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site SMD11_RS18150 351c7008aae0f64233c734ac6723e2a2 182 SUPERFAMILY SSF46785 25 168 1.99E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS18150 351c7008aae0f64233c734ac6723e2a2 182 Gene3D G3DSA:1.10.10.10 19 170 1.9E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30045 9cbc8e045c1231189d18a2375255834c 462 Pfam PF14684 Tricorn protease C1 domain 129 193 2.5E-9 T 06-07-2017 IPR028204 Tricorn protease C1 domain SMD11_RS30045 9cbc8e045c1231189d18a2375255834c 462 Gene3D G3DSA:3.90.226.10 238 459 3.1E-32 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS30045 9cbc8e045c1231189d18a2375255834c 462 Pfam PF03572 Peptidase family S41 248 429 7.5E-25 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMD11_RS30045 9cbc8e045c1231189d18a2375255834c 462 SUPERFAMILY SSF52096 127 458 2.15E-40 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS30045 9cbc8e045c1231189d18a2375255834c 462 SMART SM00245 220 433 3.9E-5 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 SMD11_RS30045 9cbc8e045c1231189d18a2375255834c 462 Gene3D G3DSA:3.30.750.44 130 192 7.2E-10 T 06-07-2017 SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 SUPERFAMILY SSF48592 6 133 5.16E-76 T 06-07-2017 SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 SUPERFAMILY SSF48592 404 518 5.16E-76 T 06-07-2017 SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 1.7E-249 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 Gene3D G3DSA:1.10.560.10 6 194 1.5E-48 T 06-07-2017 IPR027413 GroEL-like equatorial domain SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 Gene3D G3DSA:3.50.7.10 195 368 2.4E-92 T 06-07-2017 IPR027409 GroEL-like apical domain SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 06-07-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 SUPERFAMILY SSF52029 184 374 1.03E-82 T 06-07-2017 IPR027409 GroEL-like apical domain SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 Hamap MF_00600 60 kDa chaperonin [groL]. 1 538 41.581 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 PRINTS PR00298 60kDa chaperonin signature 348 373 3.8E-70 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 PRINTS PR00298 60kDa chaperonin signature 26 52 3.8E-70 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 PRINTS PR00298 60kDa chaperonin signature 396 417 3.8E-70 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 PRINTS PR00298 60kDa chaperonin signature 266 289 3.8E-70 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 PRINTS PR00298 60kDa chaperonin signature 82 109 3.8E-70 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 Gene3D G3DSA:1.10.560.10 369 515 5.4E-40 T 06-07-2017 IPR027413 GroEL-like equatorial domain SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 SUPERFAMILY SSF54849 137 202 6.18E-27 T 06-07-2017 SMD11_RS13905 16f2cbe32a0ffaeb29a82edf12bb2c79 540 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.8E-97 T 06-07-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 SMD11_RS30940 1d4d316847d5b3c975ca0e79cef35867 321 SUPERFAMILY SSF102198 118 320 3.14E-18 T 06-07-2017 SMD11_RS30940 1d4d316847d5b3c975ca0e79cef35867 321 Gene3D G3DSA:3.50.30.50 119 320 4.8E-23 T 06-07-2017 SMD11_RS30940 1d4d316847d5b3c975ca0e79cef35867 321 Pfam PF04199 Putative cyclase 118 248 5.3E-13 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 SMD11_RS08345 7d0d38b693c3b3b7788b01b3b0f0c158 218 Gene3D G3DSA:3.40.50.300 16 193 1.5E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08345 7d0d38b693c3b3b7788b01b3b0f0c158 218 Pfam PF03029 Conserved hypothetical ATP binding protein 25 191 1.9E-22 T 06-07-2017 IPR004130 GPN-loop GTPase SMD11_RS08345 7d0d38b693c3b3b7788b01b3b0f0c158 218 SUPERFAMILY SSF52540 20 194 1.91E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16435 c55b27c5c1fac066838bf86654337533 621 SUPERFAMILY SSF81296 30 128 5.95E-24 T 06-07-2017 IPR014756 Immunoglobulin E-set SMD11_RS16435 c55b27c5c1fac066838bf86654337533 621 Gene3D G3DSA:2.60.40.1220 30 128 4.8E-27 T 06-07-2017 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like SMD11_RS16435 c55b27c5c1fac066838bf86654337533 621 Pfam PF05751 FixH 527 606 1.8E-5 T 06-07-2017 IPR008620 Nitrogen fixation protein FixH SMD11_RS16435 c55b27c5c1fac066838bf86654337533 621 Pfam PF04234 CopC domain 31 127 6.9E-24 T 06-07-2017 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 SMD11_RS16435 c55b27c5c1fac066838bf86654337533 621 Pfam PF05425 Copper resistance protein D 336 479 1.0E-15 T 06-07-2017 IPR008457 Copper resistance protein D GO:0016021 SMD11_RS13570 5186280d84c8683aff19bd0b42514dad 471 Pfam PF01494 FAD binding domain 11 340 6.9E-87 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS13570 5186280d84c8683aff19bd0b42514dad 471 SUPERFAMILY SSF51905 272 385 1.4E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13570 5186280d84c8683aff19bd0b42514dad 471 SUPERFAMILY SSF51905 12 174 1.4E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13570 5186280d84c8683aff19bd0b42514dad 471 Gene3D G3DSA:3.50.50.60 264 345 3.1E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13570 5186280d84c8683aff19bd0b42514dad 471 Gene3D G3DSA:3.50.50.60 13 179 3.1E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13570 5186280d84c8683aff19bd0b42514dad 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 1.3E-45 T 06-07-2017 SMD11_RS13570 5186280d84c8683aff19bd0b42514dad 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 1.3E-45 T 06-07-2017 SMD11_RS13570 5186280d84c8683aff19bd0b42514dad 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 1.3E-45 T 06-07-2017 SMD11_RS13570 5186280d84c8683aff19bd0b42514dad 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 309 327 1.3E-45 T 06-07-2017 SMD11_RS13570 5186280d84c8683aff19bd0b42514dad 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 327 343 1.3E-45 T 06-07-2017 SMD11_RS13570 5186280d84c8683aff19bd0b42514dad 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 1.3E-45 T 06-07-2017 SMD11_RS29610 8f485134f762da415008c6cc9a11151f 564 Pfam PF08031 Berberine and berberine like 500 552 1.8E-18 T 06-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 SMD11_RS29610 8f485134f762da415008c6cc9a11151f 564 Pfam PF01565 FAD binding domain 70 206 7.3E-24 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD11_RS29610 8f485134f762da415008c6cc9a11151f 564 SUPERFAMILY SSF56176 47 243 1.64E-39 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS29610 8f485134f762da415008c6cc9a11151f 564 Gene3D G3DSA:3.30.465.10 128 242 7.4E-9 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS29610 8f485134f762da415008c6cc9a11151f 564 Gene3D G3DSA:3.30.43.10 67 127 3.7E-8 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS10025 1f0f231ee613e25e50beeddccccc6f59 298 Gene3D G3DSA:1.10.1040.10 181 289 6.7E-6 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS10025 1f0f231ee613e25e50beeddccccc6f59 298 PIRSF PIRSF000103 2 295 1.5E-37 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 SMD11_RS10025 1f0f231ee613e25e50beeddccccc6f59 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 8 154 1.9E-21 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 SMD11_RS10025 1f0f231ee613e25e50beeddccccc6f59 298 SUPERFAMILY SSF48179 178 289 2.04E-5 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS10025 1f0f231ee613e25e50beeddccccc6f59 298 SUPERFAMILY SSF51735 7 154 2.1E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS10025 1f0f231ee613e25e50beeddccccc6f59 298 Gene3D G3DSA:3.40.50.720 5 155 2.2E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS07220 12e61571d94ba3f6e8f4190755e58538 365 Gene3D G3DSA:3.40.190.10 149 264 4.1E-17 T 06-07-2017 SMD11_RS07220 12e61571d94ba3f6e8f4190755e58538 365 SUPERFAMILY SSF53850 48 279 1.95E-37 T 06-07-2017 SMD11_RS07220 12e61571d94ba3f6e8f4190755e58538 365 Pfam PF13379 NMT1-like family 48 284 1.3E-27 T 06-07-2017 SMD11_RS07220 12e61571d94ba3f6e8f4190755e58538 365 Gene3D G3DSA:3.40.190.10 71 148 1.3E-4 T 06-07-2017 SMD11_RS07220 12e61571d94ba3f6e8f4190755e58538 365 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 50 343 5.3E-59 T 06-07-2017 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 SMD11_RS24470 e45919cab985eb04cca81a9715ec037d 186 Pfam PF00484 Carbonic anhydrase 53 150 2.2E-11 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS24470 e45919cab985eb04cca81a9715ec037d 186 Gene3D G3DSA:3.40.1050.10 25 183 1.6E-33 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS24470 e45919cab985eb04cca81a9715ec037d 186 SUPERFAMILY SSF53056 21 183 1.19E-34 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS24470 e45919cab985eb04cca81a9715ec037d 186 SMART SM00947 45 183 4.8E-26 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SMD11_RS01830 1f385980538848746586ee2f30723bea 90 Pfam PF08962 Domain of unknown function (DUF1876) 5 86 5.2E-30 T 06-07-2017 IPR015057 Protein of unknown function DUF1876 SMD11_RS01830 1f385980538848746586ee2f30723bea 90 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 7 83 3.0E-13 T 06-07-2017 IPR015057 Protein of unknown function DUF1876 SMD11_RS01830 1f385980538848746586ee2f30723bea 90 SUPERFAMILY SSF143212 5 83 4.71E-24 T 06-07-2017 SMD11_RS27060 6f5b9cf15133c08d734fda10a9bf0b31 167 Gene3D G3DSA:3.40.30.10 4 162 9.9E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS27060 6f5b9cf15133c08d734fda10a9bf0b31 167 Pfam PF01323 DSBA-like thioredoxin domain 10 158 6.8E-20 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMD11_RS27060 6f5b9cf15133c08d734fda10a9bf0b31 167 SUPERFAMILY SSF52833 5 159 5.91E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS28320 54176e909af562f9a1897fee5812bcaf 477 SUPERFAMILY SSF48264 17 418 3.8E-64 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS28320 54176e909af562f9a1897fee5812bcaf 477 Gene3D G3DSA:1.10.630.10 16 419 3.1E-90 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS28320 54176e909af562f9a1897fee5812bcaf 477 PRINTS PR00359 B-class P450 signature 118 129 4.3E-23 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS28320 54176e909af562f9a1897fee5812bcaf 477 PRINTS PR00359 B-class P450 signature 311 338 4.3E-23 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS28320 54176e909af562f9a1897fee5812bcaf 477 PRINTS PR00359 B-class P450 signature 215 237 4.3E-23 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS28320 54176e909af562f9a1897fee5812bcaf 477 PRINTS PR00359 B-class P450 signature 164 180 4.3E-23 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS28320 54176e909af562f9a1897fee5812bcaf 477 PRINTS PR00359 B-class P450 signature 181 196 4.3E-23 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS28320 54176e909af562f9a1897fee5812bcaf 477 PRINTS PR00359 B-class P450 signature 358 367 4.3E-23 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS28320 54176e909af562f9a1897fee5812bcaf 477 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 360 369 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS25255 a47db3eba9f3f9550177cb79352d8b9b 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 1.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS25255 a47db3eba9f3f9550177cb79352d8b9b 182 Gene3D G3DSA:1.10.357.10 8 176 1.9E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS25255 a47db3eba9f3f9550177cb79352d8b9b 182 Pfam PF13977 Bacterial transcriptional repressor 107 176 2.0E-6 T 06-07-2017 SMD11_RS25255 a47db3eba9f3f9550177cb79352d8b9b 182 SUPERFAMILY SSF48498 85 178 3.24E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS25255 a47db3eba9f3f9550177cb79352d8b9b 182 SUPERFAMILY SSF46689 3 80 2.36E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS32365 1c574ddeb82a5919da9d9b9c72f39a7f 352 Gene3D G3DSA:3.40.640.10 5 234 1.3E-78 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS32365 1c574ddeb82a5919da9d9b9c72f39a7f 352 PIRSF PIRSF000390 1 351 2.2E-96 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMD11_RS32365 1c574ddeb82a5919da9d9b9c72f39a7f 352 SUPERFAMILY SSF53383 4 349 1.55E-100 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS32365 1c574ddeb82a5919da9d9b9c72f39a7f 352 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 14 345 6.8E-99 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMD11_RS32365 1c574ddeb82a5919da9d9b9c72f39a7f 352 Gene3D G3DSA:3.90.1150.10 237 350 1.4E-18 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS06795 216da420a4b67482437cbb589100bfcb 415 SUPERFAMILY SSF56059 106 325 2.3E-41 T 06-07-2017 SMD11_RS06795 216da420a4b67482437cbb589100bfcb 415 SMART SM01209 113 290 0.0077 T 06-07-2017 SMD11_RS06795 216da420a4b67482437cbb589100bfcb 415 Pfam PF13535 ATP-grasp domain 148 297 9.9E-19 T 06-07-2017 SMD11_RS06795 216da420a4b67482437cbb589100bfcb 415 Gene3D G3DSA:3.30.470.20 106 326 2.4E-34 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS04150 9ef08c8ebe481fce759d0eba6173c33e 523 Pfam PF07690 Major Facilitator Superfamily 17 407 2.3E-58 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS04150 9ef08c8ebe481fce759d0eba6173c33e 523 SUPERFAMILY SSF103473 6 201 7.46E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS04150 9ef08c8ebe481fce759d0eba6173c33e 523 SUPERFAMILY SSF103473 247 458 7.46E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS04150 9ef08c8ebe481fce759d0eba6173c33e 523 PRINTS PR01035 Tetracycline resistance protein signature 138 160 5.3E-6 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD11_RS04150 9ef08c8ebe481fce759d0eba6173c33e 523 PRINTS PR01035 Tetracycline resistance protein signature 25 41 5.3E-6 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SMD11_RS04150 9ef08c8ebe481fce759d0eba6173c33e 523 Gene3D G3DSA:1.20.1250.20 11 198 3.9E-33 T 06-07-2017 SMD11_RS04150 9ef08c8ebe481fce759d0eba6173c33e 523 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 417 5.5E-79 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS04150 9ef08c8ebe481fce759d0eba6173c33e 523 Gene3D G3DSA:1.20.1250.20 268 458 6.3E-21 T 06-07-2017 SMD11_RS04420 62ffc214d12a255b84ebad5de0f615e6 334 Pfam PF00294 pfkB family carbohydrate kinase 10 322 2.6E-65 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB SMD11_RS04420 62ffc214d12a255b84ebad5de0f615e6 334 Gene3D G3DSA:3.40.1190.20 8 326 1.9E-93 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS04420 62ffc214d12a255b84ebad5de0f615e6 334 PRINTS PR00990 Ribokinase signature 221 232 1.9E-31 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 SMD11_RS04420 62ffc214d12a255b84ebad5de0f615e6 334 PRINTS PR00990 Ribokinase signature 39 58 1.9E-31 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 SMD11_RS04420 62ffc214d12a255b84ebad5de0f615e6 334 PRINTS PR00990 Ribokinase signature 180 195 1.9E-31 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 SMD11_RS04420 62ffc214d12a255b84ebad5de0f615e6 334 PRINTS PR00990 Ribokinase signature 12 33 1.9E-31 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 SMD11_RS04420 62ffc214d12a255b84ebad5de0f615e6 334 PRINTS PR00990 Ribokinase signature 111 124 1.9E-31 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 SMD11_RS04420 62ffc214d12a255b84ebad5de0f615e6 334 Hamap MF_01987 Ribokinase [rbsK]. 8 329 26.053 T 06-07-2017 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 SMD11_RS04420 62ffc214d12a255b84ebad5de0f615e6 334 SUPERFAMILY SSF53613 8 326 2.18E-79 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS04420 62ffc214d12a255b84ebad5de0f615e6 334 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 274 287 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMD11_RS05590 2fef3c5e6b35f3b5827470cead4d60b5 351 Pfam PF00891 O-methyltransferase 115 326 6.3E-39 T 06-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 SMD11_RS05590 2fef3c5e6b35f3b5827470cead4d60b5 351 SUPERFAMILY SSF53335 116 333 5.8E-41 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS05590 2fef3c5e6b35f3b5827470cead4d60b5 351 SUPERFAMILY SSF46785 25 103 3.36E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05590 2fef3c5e6b35f3b5827470cead4d60b5 351 Gene3D G3DSA:3.40.50.150 113 333 9.3E-57 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS05590 2fef3c5e6b35f3b5827470cead4d60b5 351 PIRSF PIRSF005739 23 334 1.4E-31 T 06-07-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 SMD11_RS05590 2fef3c5e6b35f3b5827470cead4d60b5 351 Gene3D G3DSA:1.10.10.10 33 104 4.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23305 16144307177d12c020ef776ee1902fd2 391 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 31 372 5.3E-131 T 06-07-2017 SMD11_RS23305 16144307177d12c020ef776ee1902fd2 391 Gene3D G3DSA:3.20.20.60 36 316 9.7E-42 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS23305 16144307177d12c020ef776ee1902fd2 391 SUPERFAMILY SSF51621 35 253 4.29E-26 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS23305 16144307177d12c020ef776ee1902fd2 391 SUPERFAMILY SSF51621 283 316 4.29E-26 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS07960 c7c66731d454ed578cee9780fcc2e086 307 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 2 228 6.4E-92 T 06-07-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c SMD11_RS07960 c7c66731d454ed578cee9780fcc2e086 307 SUPERFAMILY SSF51679 4 303 2.36E-67 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS07960 c7c66731d454ed578cee9780fcc2e086 307 Pfam PF00296 Luciferase-like monooxygenase 8 245 3.2E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS07960 c7c66731d454ed578cee9780fcc2e086 307 Gene3D G3DSA:3.20.20.30 8 302 4.7E-75 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS29410 8aeff8df552b2ccc6a4eb6b7a50f0c39 270 Gene3D G3DSA:3.40.50.150 8 63 6.5E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29410 8aeff8df552b2ccc6a4eb6b7a50f0c39 270 Gene3D G3DSA:3.40.50.150 101 124 6.5E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29410 8aeff8df552b2ccc6a4eb6b7a50f0c39 270 SUPERFAMILY SSF53335 14 63 7.31E-6 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29410 8aeff8df552b2ccc6a4eb6b7a50f0c39 270 SUPERFAMILY SSF53335 99 127 7.31E-6 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS31280 cacae0aa89bdea4423612e6f95daf360 123 SUPERFAMILY SSF51306 1 120 1.72E-19 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C SMD11_RS31280 cacae0aa89bdea4423612e6f95daf360 123 Gene3D G3DSA:2.10.109.10 1 119 1.6E-16 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain SMD11_RS31280 cacae0aa89bdea4423612e6f95daf360 123 Pfam PF00717 Peptidase S24-like 1 60 1.1E-5 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B SMD11_RS31280 cacae0aa89bdea4423612e6f95daf360 123 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 56 68 1.9E-7 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS31280 cacae0aa89bdea4423612e6f95daf360 123 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 84 103 1.9E-7 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS21035 4e4feb78d77b985a3fa6a19394f83736 313 SUPERFAMILY SSF161098 69 300 1.83E-51 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21035 4e4feb78d77b985a3fa6a19394f83736 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 1.5E-9 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21035 4e4feb78d77b985a3fa6a19394f83736 313 Gene3D G3DSA:1.10.3720.10 16 301 1.6E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS00130 9af4152f9ae0b1fe02835cd6a2d7863d 180 SUPERFAMILY SSF46785 19 156 3.8E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00130 9af4152f9ae0b1fe02835cd6a2d7863d 180 Pfam PF12840 Helix-turn-helix domain 21 78 3.3E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00130 9af4152f9ae0b1fe02835cd6a2d7863d 180 Gene3D G3DSA:1.10.10.10 20 93 9.6E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00130 9af4152f9ae0b1fe02835cd6a2d7863d 180 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 4.5E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS00130 9af4152f9ae0b1fe02835cd6a2d7863d 180 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 4.5E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS00130 9af4152f9ae0b1fe02835cd6a2d7863d 180 SMART SM00418 21 100 6.3E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS09365 65145f164b0b5ebc7205863b6cfddcb9 504 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS09365 65145f164b0b5ebc7205863b6cfddcb9 504 Gene3D G3DSA:3.40.309.10 273 451 1.5E-61 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS09365 65145f164b0b5ebc7205863b6cfddcb9 504 SUPERFAMILY SSF53720 15 487 3.8E-155 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS09365 65145f164b0b5ebc7205863b6cfddcb9 504 Pfam PF00171 Aldehyde dehydrogenase family 29 484 4.3E-165 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS09365 65145f164b0b5ebc7205863b6cfddcb9 504 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS09365 65145f164b0b5ebc7205863b6cfddcb9 504 Gene3D G3DSA:3.40.605.10 17 272 2.5E-91 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS19670 09681f241d51d6f2e605158144ba240d 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 205 223 1.0E-7 T 06-07-2017 SMD11_RS19670 09681f241d51d6f2e605158144ba240d 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 1.0E-7 T 06-07-2017 SMD11_RS19670 09681f241d51d6f2e605158144ba240d 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 1.0E-7 T 06-07-2017 SMD11_RS19670 09681f241d51d6f2e605158144ba240d 502 Gene3D G3DSA:1.20.1250.20 267 473 3.1E-13 T 06-07-2017 SMD11_RS19670 09681f241d51d6f2e605158144ba240d 502 Gene3D G3DSA:1.20.1250.20 5 195 6.4E-31 T 06-07-2017 SMD11_RS19670 09681f241d51d6f2e605158144ba240d 502 SUPERFAMILY SSF103473 250 472 1.7E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS19670 09681f241d51d6f2e605158144ba240d 502 SUPERFAMILY SSF103473 5 198 1.7E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS19670 09681f241d51d6f2e605158144ba240d 502 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 444 2.2E-76 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS19670 09681f241d51d6f2e605158144ba240d 502 Pfam PF07690 Major Facilitator Superfamily 18 413 2.1E-52 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS19670 09681f241d51d6f2e605158144ba240d 502 ProSitePatterns PS00216 Sugar transport proteins signature 1. 68 84 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS08235 96018ee6f364fa870bf25fa10d506e24 502 Gene3D G3DSA:2.30.38.10 333 408 1.4E-17 T 06-07-2017 SMD11_RS08235 96018ee6f364fa870bf25fa10d506e24 502 Pfam PF00501 AMP-binding enzyme 21 415 4.0E-70 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS08235 96018ee6f364fa870bf25fa10d506e24 502 Gene3D G3DSA:3.40.50.980 167 326 3.2E-33 T 06-07-2017 SMD11_RS08235 96018ee6f364fa870bf25fa10d506e24 502 Gene3D G3DSA:3.30.300.30 410 501 4.6E-17 T 06-07-2017 SMD11_RS08235 96018ee6f364fa870bf25fa10d506e24 502 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS08235 96018ee6f364fa870bf25fa10d506e24 502 SUPERFAMILY SSF56801 6 500 7.46E-107 T 06-07-2017 SMD11_RS08235 96018ee6f364fa870bf25fa10d506e24 502 Gene3D G3DSA:3.40.50.980 7 166 1.9E-28 T 06-07-2017 SMD11_RS15920 c2af100d2021f5cf317a7512a74c43d3 523 Pfam PF00501 AMP-binding enzyme 17 427 4.2E-38 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS15920 c2af100d2021f5cf317a7512a74c43d3 523 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS15920 c2af100d2021f5cf317a7512a74c43d3 523 Gene3D G3DSA:3.40.50.980 14 182 2.0E-19 T 06-07-2017 SMD11_RS15920 c2af100d2021f5cf317a7512a74c43d3 523 Gene3D G3DSA:3.40.50.980 183 337 2.2E-10 T 06-07-2017 SMD11_RS15920 c2af100d2021f5cf317a7512a74c43d3 523 SUPERFAMILY SSF56801 13 515 2.09E-58 T 06-07-2017 SMD11_RS15920 c2af100d2021f5cf317a7512a74c43d3 523 Gene3D G3DSA:2.30.38.10 347 422 1.1E-8 T 06-07-2017 SMD11_RS28595 d5b602e630f68ced01dca859dfa7f503 256 Pfam PF13649 Methyltransferase domain 47 136 6.2E-12 T 06-07-2017 SMD11_RS28595 d5b602e630f68ced01dca859dfa7f503 256 Gene3D G3DSA:3.40.50.150 14 227 1.2E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS28595 d5b602e630f68ced01dca859dfa7f503 256 SUPERFAMILY SSF53335 10 229 1.13E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS05185 184e545d39d26964dae2ff61704b451f 463 SUPERFAMILY SSF48452 238 420 2.93E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS05185 184e545d39d26964dae2ff61704b451f 463 SUPERFAMILY SSF47413 13 70 7.04E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS05185 184e545d39d26964dae2ff61704b451f 463 Pfam PF13560 Helix-turn-helix domain 17 71 4.4E-8 T 06-07-2017 SMD11_RS05185 184e545d39d26964dae2ff61704b451f 463 Gene3D G3DSA:1.25.40.10 237 323 3.7E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS05185 184e545d39d26964dae2ff61704b451f 463 Gene3D G3DSA:1.10.260.40 14 58 6.2E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS04255 974561ba77127e876ea1c9e4da9e749b 415 SUPERFAMILY SSF53756 174 313 8.68E-7 T 06-07-2017 SMD11_RS04255 974561ba77127e876ea1c9e4da9e749b 415 Gene3D G3DSA:3.40.50.2000 175 322 4.2E-4 T 06-07-2017 SMD11_RS28260 d6bbc3f95e5b70afa0f291f900b345cd 227 SUPERFAMILY SSF52499 16 220 2.35E-37 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS28260 d6bbc3f95e5b70afa0f291f900b345cd 227 Pfam PF00857 Isochorismatase family 29 214 4.9E-23 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS28260 d6bbc3f95e5b70afa0f291f900b345cd 227 Gene3D G3DSA:3.40.50.850 15 222 1.0E-38 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS13770 240e26fedda6c9cff3c96e010130e449 92 Pfam PF10745 Protein of unknown function (DUF2530) 17 78 4.5E-8 T 06-07-2017 IPR019681 Protein of unknown function DUF2530 SMD11_RS08340 bdf817a96ae929eadfb37bbc96a7c29c 384 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 325 334 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS08340 bdf817a96ae929eadfb37bbc96a7c29c 384 SUPERFAMILY SSF48264 2 383 7.47E-61 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS08340 bdf817a96ae929eadfb37bbc96a7c29c 384 PRINTS PR00359 B-class P450 signature 133 149 8.6E-16 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08340 bdf817a96ae929eadfb37bbc96a7c29c 384 PRINTS PR00359 B-class P450 signature 183 205 8.6E-16 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08340 bdf817a96ae929eadfb37bbc96a7c29c 384 PRINTS PR00359 B-class P450 signature 87 98 8.6E-16 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08340 bdf817a96ae929eadfb37bbc96a7c29c 384 PRINTS PR00359 B-class P450 signature 261 272 8.6E-16 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08340 bdf817a96ae929eadfb37bbc96a7c29c 384 PRINTS PR00359 B-class P450 signature 279 306 8.6E-16 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS08340 bdf817a96ae929eadfb37bbc96a7c29c 384 Gene3D G3DSA:1.10.630.10 1 383 1.6E-86 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS26525 b53b47d50d8cd41238c27c7824120698 281 Pfam PF00227 Proteasome subunit 52 230 8.6E-36 T 06-07-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 SMD11_RS26525 b53b47d50d8cd41238c27c7824120698 281 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 50 269 7.5E-116 T 06-07-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 SMD11_RS26525 b53b47d50d8cd41238c27c7824120698 281 Gene3D G3DSA:3.60.20.10 54 262 3.5E-54 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS26525 b53b47d50d8cd41238c27c7824120698 281 SUPERFAMILY SSF56235 47 264 1.55E-57 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS26525 b53b47d50d8cd41238c27c7824120698 281 Hamap MF_02113_B Proteasome subunit beta [prcB]. 7 275 50.244 T 06-07-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 SMD11_RS02235 f8ca47e26c2b55ffa66754a177a0c299 174 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 12 158 9.6E-41 T 06-07-2017 IPR011747 Conserved hypothetical protein CHP02241 SMD11_RS02235 f8ca47e26c2b55ffa66754a177a0c299 174 Pfam PF06841 T4-like virus tail tube protein gp19 15 157 3.2E-39 T 06-07-2017 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 SMD11_RS04830 b13b861123057676da5f51e7e60ad9c7 172 Gene3D G3DSA:1.10.1220.10 109 149 4.6E-9 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMD11_RS04830 b13b861123057676da5f51e7e60ad9c7 172 SUPERFAMILY SSF47598 107 170 5.78E-10 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 SMD11_RS23540 9c457a110fd64067f2faec313c220e6a 244 Pfam PF08241 Methyltransferase domain 18 121 1.1E-22 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS23540 9c457a110fd64067f2faec313c220e6a 244 SUPERFAMILY SSF53335 9 236 6.04E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS23540 9c457a110fd64067f2faec313c220e6a 244 Gene3D G3DSA:3.40.50.150 8 237 1.8E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS13875 0abe899df7b8e10cc586c84a4f5c0edd 221 Gene3D G3DSA:1.10.3210.10 39 148 3.7E-11 T 06-07-2017 IPR006674 HD domain SMD11_RS13875 0abe899df7b8e10cc586c84a4f5c0edd 221 SUPERFAMILY SSF109604 35 211 3.81E-29 T 06-07-2017 SMD11_RS13875 0abe899df7b8e10cc586c84a4f5c0edd 221 PIRSF PIRSF035170 8 221 4.5E-73 T 06-07-2017 IPR009218 Predicted HD phosphohydrolase SMD11_RS26080 a88ba76b58674113a63cc3c54a3f3afa 415 SUPERFAMILY SSF56059 98 323 1.1E-26 T 06-07-2017 SMD11_RS26080 a88ba76b58674113a63cc3c54a3f3afa 415 Gene3D G3DSA:3.30.470.20 112 324 8.9E-17 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS25485 286021b15fc43d25671d8d944371bdb9 594 SUPERFAMILY SSF48208 205 584 2.08E-105 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD11_RS25485 286021b15fc43d25671d8d944371bdb9 594 Gene3D G3DSA:1.50.10.10 212 589 6.7E-83 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 SMD11_RS25485 286021b15fc43d25671d8d944371bdb9 594 Pfam PF00723 Glycosyl hydrolases family 15 217 582 6.4E-70 T 06-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 SMD11_RS19595 34712937b6ff46095d492a20f1c7a651 599 Pfam PF13365 Trypsin-like peptidase domain 31 184 8.7E-12 T 06-07-2017 SMD11_RS19595 34712937b6ff46095d492a20f1c7a651 599 Gene3D G3DSA:2.40.10.10 16 102 2.6E-5 T 06-07-2017 SMD11_RS19595 34712937b6ff46095d492a20f1c7a651 599 SUPERFAMILY SSF50494 11 222 3.81E-16 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS15550 788999833ce65136669daec19ff2ebbb 728 Gene3D G3DSA:1.10.3810.10 77 263 2.2E-70 T 06-07-2017 SMD11_RS15550 788999833ce65136669daec19ff2ebbb 728 SUPERFAMILY SSF53955 63 286 3.94E-68 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS15550 788999833ce65136669daec19ff2ebbb 728 Gene3D G3DSA:3.40.710.10 264 684 1.0E-107 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS15550 788999833ce65136669daec19ff2ebbb 728 Pfam PF00905 Penicillin binding protein transpeptidase domain 362 629 2.0E-32 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SMD11_RS15550 788999833ce65136669daec19ff2ebbb 728 Pfam PF00912 Transglycosylase 77 261 1.3E-62 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 SMD11_RS15550 788999833ce65136669daec19ff2ebbb 728 SUPERFAMILY SSF56601 243 265 6.04E-95 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS15550 788999833ce65136669daec19ff2ebbb 728 SUPERFAMILY SSF56601 299 676 6.04E-95 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS16925 1ad5609cb617ec84a181f0502145a14d 374 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 374 96.961 T 06-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 SMD11_RS16925 1ad5609cb617ec84a181f0502145a14d 374 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 363 1.4E-127 T 06-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 SMD11_RS16925 1ad5609cb617ec84a181f0502145a14d 374 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 349 7.8E-19 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal SMD11_RS16925 1ad5609cb617ec84a181f0502145a14d 374 Gene3D G3DSA:3.40.50.300 1 166 1.2E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16925 1ad5609cb617ec84a181f0502145a14d 374 Gene3D G3DSA:3.40.50.300 245 349 1.2E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16925 1ad5609cb617ec84a181f0502145a14d 374 SUPERFAMILY SSF52540 253 348 2.75E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16925 1ad5609cb617ec84a181f0502145a14d 374 SUPERFAMILY SSF52540 1 223 2.75E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16925 1ad5609cb617ec84a181f0502145a14d 374 ProSitePatterns PS00618 RecF protein signature 2. 317 335 - T 06-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 SMD11_RS16925 1ad5609cb617ec84a181f0502145a14d 374 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 06-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 SMD11_RS20860 c50e1b7089b6d77c1c4d1cc679e9cd1f 268 SUPERFAMILY SSF53448 21 241 3.59E-40 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20860 c50e1b7089b6d77c1c4d1cc679e9cd1f 268 Pfam PF00535 Glycosyl transferase family 2 22 165 1.7E-28 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD11_RS20860 c50e1b7089b6d77c1c4d1cc679e9cd1f 268 Gene3D G3DSA:3.90.550.10 22 234 3.9E-23 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS26740 bb7b4397f875eb120fa44fbe7841db67 388 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 151 351 1.8E-37 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS26740 bb7b4397f875eb120fa44fbe7841db67 388 SMART SM00331 126 350 4.7E-28 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS26670 dcbaffeb382d3c39fe024f5e250ecce4 424 Gene3D G3DSA:3.40.50.1000 227 288 2.9E-8 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS26670 dcbaffeb382d3c39fe024f5e250ecce4 424 SUPERFAMILY SSF56784 177 344 1.44E-10 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS26670 dcbaffeb382d3c39fe024f5e250ecce4 424 SUPERFAMILY SSF56784 74 89 1.44E-10 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS26670 dcbaffeb382d3c39fe024f5e250ecce4 424 Pfam PF12710 haloacid dehalogenase-like hydrolase 226 330 3.0E-6 T 06-07-2017 SMD11_RS00890 c0af916c6d63f475a6be069483c7e7ec 187 SUPERFAMILY SSF53597 1 184 7.85E-33 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD11_RS00890 c0af916c6d63f475a6be069483c7e7ec 187 Pfam PF01872 RibD C-terminal domain 2 180 1.3E-23 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD11_RS00890 c0af916c6d63f475a6be069483c7e7ec 187 Gene3D G3DSA:3.40.430.10 3 186 1.8E-31 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD11_RS17445 982e8c8f36ab3f507950c369a1095c32 318 Gene3D G3DSA:3.30.870.10 120 240 7.9E-5 T 06-07-2017 SMD11_RS17445 982e8c8f36ab3f507950c369a1095c32 318 SUPERFAMILY SSF56024 60 95 8.37E-6 T 06-07-2017 SMD11_RS17445 982e8c8f36ab3f507950c369a1095c32 318 SUPERFAMILY SSF56024 169 250 8.37E-6 T 06-07-2017 SMD11_RS17445 982e8c8f36ab3f507950c369a1095c32 318 SUPERFAMILY SSF46894 256 311 1.77E-8 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS17445 982e8c8f36ab3f507950c369a1095c32 318 Gene3D G3DSA:1.10.10.10 256 312 9.5E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17445 982e8c8f36ab3f507950c369a1095c32 318 Pfam PF13384 Homeodomain-like domain 260 289 9.1E-6 T 06-07-2017 SMD11_RS17445 982e8c8f36ab3f507950c369a1095c32 318 SMART SM00421 252 306 0.0016 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS04525 028fd215dff0b30113817968c2ac6c16 456 Gene3D G3DSA:1.20.1250.20 2 173 1.4E-29 T 06-07-2017 SMD11_RS04525 028fd215dff0b30113817968c2ac6c16 456 Gene3D G3DSA:1.20.1250.20 241 446 4.7E-17 T 06-07-2017 SMD11_RS04525 028fd215dff0b30113817968c2ac6c16 456 Pfam PF07690 Major Facilitator Superfamily 2 388 5.7E-50 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS04525 028fd215dff0b30113817968c2ac6c16 456 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 2 397 3.8E-84 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS04525 028fd215dff0b30113817968c2ac6c16 456 SUPERFAMILY SSF103473 2 174 2.88E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS04525 028fd215dff0b30113817968c2ac6c16 456 SUPERFAMILY SSF103473 227 437 2.88E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS11215 74ec0881b0881e6eab9272743d2181c4 532 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 525 4.7E-104 T 06-07-2017 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 SMD11_RS11215 74ec0881b0881e6eab9272743d2181c4 532 Pfam PF00999 Sodium/hydrogen exchanger family 8 404 2.2E-61 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMD11_RS31305 7fcc2d3324340ff9f2ce701762abf7d5 68 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 5 47 1.3E-5 T 06-07-2017 IPR019239 Bacterial antitoxin of type II TA system, VapB SMD11_RS16445 ef01e03bb9d0877bf38b324db1650a36 311 Gene3D G3DSA:3.40.190.10 94 171 6.4E-20 T 06-07-2017 SMD11_RS16445 ef01e03bb9d0877bf38b324db1650a36 311 PIRSF PIRSF001500 2 279 9.8E-58 T 06-07-2017 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 SMD11_RS16445 ef01e03bb9d0877bf38b324db1650a36 311 Gene3D G3DSA:3.40.190.10 5 93 2.6E-25 T 06-07-2017 SMD11_RS16445 ef01e03bb9d0877bf38b324db1650a36 311 SUPERFAMILY SSF55021 185 276 7.08E-22 T 06-07-2017 SMD11_RS16445 ef01e03bb9d0877bf38b324db1650a36 311 Pfam PF01842 ACT domain 197 259 2.4E-8 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 SMD11_RS16445 ef01e03bb9d0877bf38b324db1650a36 311 Pfam PF00800 Prephenate dehydratase 8 183 1.1E-46 T 06-07-2017 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 SMD11_RS16445 ef01e03bb9d0877bf38b324db1650a36 311 SUPERFAMILY SSF53850 5 188 1.83E-49 T 06-07-2017 SMD11_RS16445 ef01e03bb9d0877bf38b324db1650a36 311 Gene3D G3DSA:3.30.70.260 190 277 4.5E-29 T 06-07-2017 SMD11_RS01245 2b8bf2aa165d492e08f040ab3b23cd82 222 Gene3D G3DSA:1.10.357.10 65 188 3.9E-16 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS01245 2b8bf2aa165d492e08f040ab3b23cd82 222 SUPERFAMILY SSF46689 11 68 3.33E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS01245 2b8bf2aa165d492e08f040ab3b23cd82 222 SUPERFAMILY SSF48498 78 206 4.45E-12 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS01245 2b8bf2aa165d492e08f040ab3b23cd82 222 Gene3D G3DSA:1.10.10.60 11 64 9.4E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS01245 2b8bf2aa165d492e08f040ab3b23cd82 222 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 76 183 1.0E-5 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 SMD11_RS02350 5ca03051eaeaeaf6be12f5f930138182 214 SUPERFAMILY SSF55961 3 150 1.74E-5 T 06-07-2017 SMD11_RS10605 1cd641904a15945cd4dcd4307faca35b 110 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 93 2.8E-27 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane SMD11_RS10605 1cd641904a15945cd4dcd4307faca35b 110 Pfam PF12823 Domain of unknown function (DUF3817) 6 93 2.8E-27 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane SMD11_RS16535 2c1c42f84ee107f19453be4c584edd97 293 Pfam PF08282 haloacid dehalogenase-like hydrolase 26 283 4.9E-46 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS16535 2c1c42f84ee107f19453be4c584edd97 293 Gene3D G3DSA:3.40.50.1000 22 93 3.4E-45 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS16535 2c1c42f84ee107f19453be4c584edd97 293 Gene3D G3DSA:3.40.50.1000 191 288 3.4E-45 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS16535 2c1c42f84ee107f19453be4c584edd97 293 SUPERFAMILY SSF56784 22 287 1.36E-57 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS33420 402c59dd3c964e72c9f9fef0623670c2 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 348 357 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS33420 402c59dd3c964e72c9f9fef0623670c2 407 SUPERFAMILY SSF48264 4 407 4.71E-69 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS33420 402c59dd3c964e72c9f9fef0623670c2 407 Gene3D G3DSA:1.10.630.10 20 407 6.6E-85 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS33420 402c59dd3c964e72c9f9fef0623670c2 407 Pfam PF00067 Cytochrome P450 280 375 3.7E-15 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS33420 402c59dd3c964e72c9f9fef0623670c2 407 PRINTS PR00359 B-class P450 signature 143 159 1.0E-5 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS33420 402c59dd3c964e72c9f9fef0623670c2 407 PRINTS PR00359 B-class P450 signature 96 107 1.0E-5 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS29015 239576dc6e425c523c5fdb4aed4bbcb0 644 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 259 644 7.6E-100 T 06-07-2017 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component SMD11_RS29015 239576dc6e425c523c5fdb4aed4bbcb0 644 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 258 599 5.0E-83 T 06-07-2017 IPR003776 YcaO-like domain SMD11_RS29015 239576dc6e425c523c5fdb4aed4bbcb0 644 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 54 223 4.1E-18 T 06-07-2017 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain SMD11_RS23825 f9d501ff276b83c93d5e7c5b8cc37fbc 234 Pfam PF01323 DSBA-like thioredoxin domain 2 203 6.1E-36 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 SMD11_RS23825 f9d501ff276b83c93d5e7c5b8cc37fbc 234 SUPERFAMILY SSF52833 2 208 1.9E-41 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS23825 f9d501ff276b83c93d5e7c5b8cc37fbc 234 Gene3D G3DSA:3.40.30.10 2 206 1.2E-43 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS28635 31d52b86cb12a77be69af10cb193386c 348 Gene3D G3DSA:3.20.20.100 2 304 3.4E-87 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS28635 31d52b86cb12a77be69af10cb193386c 348 Pfam PF00248 Aldo/keto reductase family 15 304 5.0E-62 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS28635 31d52b86cb12a77be69af10cb193386c 348 SUPERFAMILY SSF51430 2 304 8.12E-89 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS04800 fb2d40588b9ecbd0be6519e566fe258e 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 288 1.4E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS04800 fb2d40588b9ecbd0be6519e566fe258e 296 SUPERFAMILY SSF161098 77 276 6.67E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS04800 fb2d40588b9ecbd0be6519e566fe258e 296 Gene3D G3DSA:1.10.3720.10 79 290 7.5E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS34385 f34760203788782f8cadd60a4441f3a8 418 Pfam PF13692 Glycosyl transferases group 1 208 288 2.9E-7 T 06-07-2017 SMD11_RS34385 f34760203788782f8cadd60a4441f3a8 418 SUPERFAMILY SSF53756 20 355 4.45E-22 T 06-07-2017 SMD11_RS08570 0568cf63159d5f6ac163ec533280913a 427 SUPERFAMILY SSF103473 15 391 3.79E-34 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS08570 0568cf63159d5f6ac163ec533280913a 427 Gene3D G3DSA:1.20.1250.20 16 186 4.2E-9 T 06-07-2017 SMD11_RS08570 0568cf63159d5f6ac163ec533280913a 427 Gene3D G3DSA:1.20.1250.20 214 393 5.7E-19 T 06-07-2017 SMD11_RS08570 0568cf63159d5f6ac163ec533280913a 427 Pfam PF07690 Major Facilitator Superfamily 219 399 8.3E-15 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS23310 370626e62b5479c3538854970d4a0ccd 909 Pfam PF15609 Phosphoribosyl transferase 25 212 4.8E-69 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS23310 370626e62b5479c3538854970d4a0ccd 909 Pfam PF12500 TRSP domain C terminus to PRTase_2 397 507 3.2E-37 T 06-07-2017 IPR022537 TRSP domain SMD11_RS23310 370626e62b5479c3538854970d4a0ccd 909 SUPERFAMILY SSF53271 26 188 4.69E-5 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS23310 370626e62b5479c3538854970d4a0ccd 909 Pfam PF15608 PELOTA RNA binding domain 812 891 3.3E-34 T 06-07-2017 IPR028157 PELOTA RNA-binding domain SMD11_RS23310 370626e62b5479c3538854970d4a0ccd 909 Pfam PF11202 Phosphoribosyl transferase (PRTase) 541 785 1.8E-106 T 06-07-2017 IPR011215 Phosphoribosyl transferase SMD11_RS01980 453864f908b7f28139bf43b6201a3424 375 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 10 342 1.7E-75 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMD11_RS01980 453864f908b7f28139bf43b6201a3424 375 SUPERFAMILY SSF51395 6 366 1.83E-110 T 06-07-2017 SMD11_RS01980 453864f908b7f28139bf43b6201a3424 375 Gene3D G3DSA:3.20.20.70 4 366 1.0E-118 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS28005 4e155f5ac1ee74141d58a6afc2e08a45 284 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 34 278 43.306 T 06-07-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF SMD11_RS28005 4e155f5ac1ee74141d58a6afc2e08a45 284 SUPERFAMILY SSF88713 36 283 5.26E-92 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS28005 4e155f5ac1ee74141d58a6afc2e08a45 284 Pfam PF03746 LamB/YcsF family 37 274 1.5E-97 T 06-07-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF SMD11_RS05440 8d5690961b10a498af55af4df0075038 201 SUPERFAMILY SSF46689 8 81 1.2E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS05440 8d5690961b10a498af55af4df0075038 201 Gene3D G3DSA:1.10.10.60 7 60 1.3E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS05440 8d5690961b10a498af55af4df0075038 201 Gene3D G3DSA:1.10.357.10 61 180 2.0E-12 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS05440 8d5690961b10a498af55af4df0075038 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 64 2.0E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS05440 8d5690961b10a498af55af4df0075038 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 4.2E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS05440 8d5690961b10a498af55af4df0075038 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 4.2E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS02735 24fd0d6144b9a4317c2fac7884652603 228 Pfam PF01464 Transglycosylase SLT domain 154 225 6.2E-8 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 SMD11_RS02735 24fd0d6144b9a4317c2fac7884652603 228 Gene3D G3DSA:1.10.530.10 149 225 5.7E-9 T 06-07-2017 SMD11_RS02735 24fd0d6144b9a4317c2fac7884652603 228 SUPERFAMILY SSF53955 134 222 2.41E-13 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS21945 9cc1988cf398059a550db79a01df8e8a 114 Gene3D G3DSA:3.30.70.120 4 110 7.9E-42 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal SMD11_RS21945 9cc1988cf398059a550db79a01df8e8a 114 SUPERFAMILY SSF54913 4 104 6.23E-32 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta SMD11_RS21945 9cc1988cf398059a550db79a01df8e8a 114 Pfam PF02641 Uncharacterized ACR, COG1993 7 103 1.7E-35 T 06-07-2017 IPR003793 Domain of unknown function DUF190 SMD11_RS00685 0ac282f7379324bde7e4c23ffcf315b2 501 Gene3D G3DSA:1.20.1250.20 8 195 9.2E-32 T 06-07-2017 SMD11_RS00685 0ac282f7379324bde7e4c23ffcf315b2 501 PRINTS PR01036 Tetracycline resistance protein TetB signature 400 419 3.9E-9 T 06-07-2017 SMD11_RS00685 0ac282f7379324bde7e4c23ffcf315b2 501 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 3.9E-9 T 06-07-2017 SMD11_RS00685 0ac282f7379324bde7e4c23ffcf315b2 501 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 3.9E-9 T 06-07-2017 SMD11_RS00685 0ac282f7379324bde7e4c23ffcf315b2 501 PRINTS PR01036 Tetracycline resistance protein TetB signature 77 99 3.9E-9 T 06-07-2017 SMD11_RS00685 0ac282f7379324bde7e4c23ffcf315b2 501 Gene3D G3DSA:1.20.1250.20 467 499 9.6E-18 T 06-07-2017 SMD11_RS00685 0ac282f7379324bde7e4c23ffcf315b2 501 Gene3D G3DSA:1.20.1250.20 261 419 9.6E-18 T 06-07-2017 SMD11_RS00685 0ac282f7379324bde7e4c23ffcf315b2 501 SUPERFAMILY SSF103473 6 197 6.71E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS00685 0ac282f7379324bde7e4c23ffcf315b2 501 SUPERFAMILY SSF103473 467 498 6.71E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS00685 0ac282f7379324bde7e4c23ffcf315b2 501 SUPERFAMILY SSF103473 248 419 6.71E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS00685 0ac282f7379324bde7e4c23ffcf315b2 501 Pfam PF07690 Major Facilitator Superfamily 20 409 3.9E-53 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS00685 0ac282f7379324bde7e4c23ffcf315b2 501 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 420 1.3E-77 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS29815 520e37b925a507253d846437cb771997 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.7E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29815 520e37b925a507253d846437cb771997 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.7E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29815 520e37b925a507253d846437cb771997 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.7E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29815 520e37b925a507253d846437cb771997 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.7E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29815 520e37b925a507253d846437cb771997 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.7E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29815 520e37b925a507253d846437cb771997 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.7E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29815 520e37b925a507253d846437cb771997 260 SUPERFAMILY SSF51735 6 257 4.65E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29815 520e37b925a507253d846437cb771997 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 5.8E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29815 520e37b925a507253d846437cb771997 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.8E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29815 520e37b925a507253d846437cb771997 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 5.8E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29815 520e37b925a507253d846437cb771997 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS29815 520e37b925a507253d846437cb771997 260 Gene3D G3DSA:3.40.50.720 5 257 2.5E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29815 520e37b925a507253d846437cb771997 260 Pfam PF00106 short chain dehydrogenase 7 200 8.3E-64 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS32670 0c18b7a766600782492652582d110282 295 SUPERFAMILY SSF51735 5 256 9.9E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32670 0c18b7a766600782492652582d110282 295 Gene3D G3DSA:3.40.50.720 5 225 8.7E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32670 0c18b7a766600782492652582d110282 295 Pfam PF05368 NmrA-like family 6 230 4.9E-50 T 06-07-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 SMD11_RS16335 46ab292cfae6f3daf36e584555eb4211 226 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 116 195 6.6E-13 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS16335 46ab292cfae6f3daf36e584555eb4211 226 SUPERFAMILY SSF56214 114 199 6.1E-12 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS16335 46ab292cfae6f3daf36e584555eb4211 226 PRINTS PR01399 Enterobactin synthetase component D signature 156 172 2.8E-13 T 06-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 SMD11_RS16335 46ab292cfae6f3daf36e584555eb4211 226 PRINTS PR01399 Enterobactin synthetase component D signature 81 99 2.8E-13 T 06-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 SMD11_RS16335 46ab292cfae6f3daf36e584555eb4211 226 PRINTS PR01399 Enterobactin synthetase component D signature 53 73 2.8E-13 T 06-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 SMD11_RS16335 46ab292cfae6f3daf36e584555eb4211 226 Gene3D G3DSA:3.90.470.20 114 221 1.2E-10 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS00185 7ca5d6b5d004eb447fb13abeaf2ae905 100 Pfam PF06803 Protein of unknown function (DUF1232) 47 78 2.0E-7 T 06-07-2017 IPR010652 Protein of unknown function DUF1232 SMD11_RS08605 fef523527fa3536739b0774075df28d2 404 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 62 389 1.6E-42 T 06-07-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 SMD11_RS08605 fef523527fa3536739b0774075df28d2 404 Gene3D G3DSA:3.40.720.10 41 334 2.4E-45 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SMD11_RS08605 fef523527fa3536739b0774075df28d2 404 SUPERFAMILY SSF53649 58 400 1.44E-57 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SMD11_RS29200 73a25e237ca5f38e84518e517f39f19f 515 Pfam PF11997 Domain of unknown function (DUF3492) 14 276 1.3E-60 T 06-07-2017 IPR022622 Domain of unknown function DUF3492 SMD11_RS29200 73a25e237ca5f38e84518e517f39f19f 515 SUPERFAMILY SSF53756 186 477 1.43E-70 T 06-07-2017 SMD11_RS29200 73a25e237ca5f38e84518e517f39f19f 515 SUPERFAMILY SSF53756 18 104 1.43E-70 T 06-07-2017 SMD11_RS29200 73a25e237ca5f38e84518e517f39f19f 515 Gene3D G3DSA:3.40.50.2000 274 454 1.1E-24 T 06-07-2017 SMD11_RS29200 73a25e237ca5f38e84518e517f39f19f 515 Pfam PF13692 Glycosyl transferases group 1 300 442 3.6E-31 T 06-07-2017 SMD11_RS33285 9df5fe0715881587b40ec36dc3c83464 297 Gene3D G3DSA:3.40.50.150 84 296 2.8E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS33285 9df5fe0715881587b40ec36dc3c83464 297 SUPERFAMILY SSF53335 51 296 1.74E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS33285 9df5fe0715881587b40ec36dc3c83464 297 Pfam PF08241 Methyltransferase domain 84 186 1.1E-12 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS30860 ba17b9a82fc01f51f5cbb9ec160eab2e 94 Pfam PF07561 Domain of Unknown Function (DUF1540) 9 40 2.7E-5 T 06-07-2017 IPR011437 Domain of unknown function DUF1540 SMD11_RS30860 ba17b9a82fc01f51f5cbb9ec160eab2e 94 Pfam PF07561 Domain of Unknown Function (DUF1540) 59 81 0.061 T 06-07-2017 IPR011437 Domain of unknown function DUF1540 SMD11_RS02705 3afc8e790caacf8542891216c7d99493 340 SUPERFAMILY SSF52540 7 254 4.14E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02705 3afc8e790caacf8542891216c7d99493 340 Pfam PF00005 ABC transporter 28 183 5.7E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS02705 3afc8e790caacf8542891216c7d99493 340 Gene3D G3DSA:3.40.50.300 6 257 2.0E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02705 3afc8e790caacf8542891216c7d99493 340 SMART SM00382 36 233 4.5E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS02705 3afc8e790caacf8542891216c7d99493 340 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 297 5.0E-18 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS02705 3afc8e790caacf8542891216c7d99493 340 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS02705 3afc8e790caacf8542891216c7d99493 340 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 326 4.1E-21 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS28785 fcc9f60196b66893755561e3c7360386 80 Pfam PF04149 Domain of unknown function (DUF397) 17 69 1.1E-20 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS00710 48bb1f34c60b0597cd7d513629387061 126 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 2 114 2.7E-20 T 06-07-2017 IPR018727 Protein of unknown function DUF2267 SMD11_RS33460 16d7915a9c404551c472471ef8ddc040 170 SUPERFAMILY SSF55729 12 124 9.45E-10 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS33460 16d7915a9c404551c472471ef8ddc040 170 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 14 166 1.1E-35 T 06-07-2017 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 SMD11_RS33460 16d7915a9c404551c472471ef8ddc040 170 Gene3D G3DSA:3.40.630.30 11 167 7.2E-44 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS27905 706aa51fe5458a2e944b8283b50d2705 291 Pfam PF13439 Glycosyltransferase Family 4 32 169 2.3E-11 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 SMD11_RS27905 706aa51fe5458a2e944b8283b50d2705 291 SUPERFAMILY SSF53756 15 227 1.36E-13 T 06-07-2017 SMD11_RS29335 4e3693c84644390a46df93861c287e3e 377 Gene3D G3DSA:1.10.10.10 281 374 2.3E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS29335 4e3693c84644390a46df93861c287e3e 377 SUPERFAMILY SSF46894 282 375 1.13E-15 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS29335 4e3693c84644390a46df93861c287e3e 377 Pfam PF02602 Uroporphyrinogen-III synthase HemD 27 268 9.3E-35 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS29335 4e3693c84644390a46df93861c287e3e 377 SUPERFAMILY SSF69618 15 275 1.7E-49 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 SMD11_RS29335 4e3693c84644390a46df93861c287e3e 377 SMART SM00862 301 373 3.0E-18 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS29335 4e3693c84644390a46df93861c287e3e 377 Pfam PF00486 Transcriptional regulatory protein, C terminal 302 373 3.9E-15 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS29335 4e3693c84644390a46df93861c287e3e 377 Gene3D G3DSA:3.40.50.10090 142 277 2.9E-33 T 06-07-2017 SMD11_RS29335 4e3693c84644390a46df93861c287e3e 377 Gene3D G3DSA:3.40.50.10090 12 139 1.0E-26 T 06-07-2017 SMD11_RS22505 037e3f53cf02768b1c62eb7bbe356aa8 547 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 459 545 7.5E-13 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMD11_RS22505 037e3f53cf02768b1c62eb7bbe356aa8 547 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 269 377 4.7E-7 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS16170 688ef7b2af1ea56d03b41df48c32011c 551 Gene3D G3DSA:3.40.50.980 11 190 3.0E-27 T 06-07-2017 SMD11_RS16170 688ef7b2af1ea56d03b41df48c32011c 551 SUPERFAMILY SSF56801 8 542 1.83E-139 T 06-07-2017 SMD11_RS16170 688ef7b2af1ea56d03b41df48c32011c 551 Gene3D G3DSA:3.40.50.980 191 342 2.1E-37 T 06-07-2017 SMD11_RS16170 688ef7b2af1ea56d03b41df48c32011c 551 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 530 1.3E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS16170 688ef7b2af1ea56d03b41df48c32011c 551 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS16170 688ef7b2af1ea56d03b41df48c32011c 551 Gene3D G3DSA:3.30.300.30 441 543 4.4E-30 T 06-07-2017 SMD11_RS16170 688ef7b2af1ea56d03b41df48c32011c 551 Pfam PF00501 AMP-binding enzyme 20 446 1.7E-84 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS16170 688ef7b2af1ea56d03b41df48c32011c 551 Gene3D G3DSA:2.30.38.10 359 440 7.5E-17 T 06-07-2017 SMD11_RS08350 8ed009457188cdab04f9168f9fe2a8f2 120 Pfam PF05331 Protein of unknown function (DUF742) 10 118 9.7E-36 T 06-07-2017 IPR007995 Protein of unknown function DUF742 SMD11_RS33195 1ba48cea9793ddf7e08f031df97a2af6 247 Gene3D G3DSA:3.40.50.300 2 147 2.4E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS33195 1ba48cea9793ddf7e08f031df97a2af6 247 SUPERFAMILY SSF53795 2 72 6.41E-5 T 06-07-2017 SMD11_RS09605 56b60fd41a20b5022106f30ae315cf49 146 Pfam PF00886 Ribosomal protein S16 9 67 8.7E-24 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09605 56b60fd41a20b5022106f30ae315cf49 146 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 06-07-2017 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS09605 56b60fd41a20b5022106f30ae315cf49 146 Gene3D G3DSA:3.30.1320.10 2 83 9.3E-33 T 06-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09605 56b60fd41a20b5022106f30ae315cf49 146 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 23.742 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09605 56b60fd41a20b5022106f30ae315cf49 146 SUPERFAMILY SSF54565 2 95 9.94E-34 T 06-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS09605 56b60fd41a20b5022106f30ae315cf49 146 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 3.6E-32 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 77 299 6.3E-96 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 PRINTS PR00046 Major sigma-70 factor signature 131 139 6.4E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 PRINTS PR00046 Major sigma-70 factor signature 284 295 6.4E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 PRINTS PR00046 Major sigma-70 factor signature 107 120 6.4E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 PRINTS PR00046 Major sigma-70 factor signature 252 264 6.4E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 PRINTS PR00046 Major sigma-70 factor signature 269 284 6.4E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 SUPERFAMILY SSF88659 156 230 1.57E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 Pfam PF04542 Sigma-70 region 2 83 152 3.1E-21 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 SUPERFAMILY SSF88946 55 152 1.15E-32 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 SUPERFAMILY SSF88659 219 299 1.05E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 Pfam PF04545 Sigma-70, region 4 248 297 2.1E-16 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 Gene3D G3DSA:1.10.10.10 151 206 1.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 Pfam PF04539 Sigma-70 region 3 164 222 5.8E-16 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 Gene3D G3DSA:1.10.601.10 71 150 1.5E-27 T 06-07-2017 SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 Gene3D G3DSA:1.10.10.10 240 299 1.1E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11235 a9332bf11c68877dd80bd6629489e644 303 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 79 299 7.4E-38 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS33315 4013aa9a1ff783d24bfa7824551a2bb8 325 SUPERFAMILY SSF55469 112 172 1.06E-8 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS33315 4013aa9a1ff783d24bfa7824551a2bb8 325 SUPERFAMILY SSF55469 226 315 1.06E-8 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS33315 4013aa9a1ff783d24bfa7824551a2bb8 325 SUPERFAMILY SSF55469 2 75 2.88E-7 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS33315 4013aa9a1ff783d24bfa7824551a2bb8 325 Gene3D G3DSA:3.40.109.10 2 67 1.9E-26 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS33315 4013aa9a1ff783d24bfa7824551a2bb8 325 Gene3D G3DSA:3.40.109.10 229 323 1.9E-26 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS13150 7a549327626d0c333c82d77586ac058a 344 SUPERFAMILY SSF53850 58 344 3.98E-53 T 06-07-2017 SMD11_RS13150 7a549327626d0c333c82d77586ac058a 344 Gene3D G3DSA:3.40.190.10 59 156 4.0E-10 T 06-07-2017 SMD11_RS13150 7a549327626d0c333c82d77586ac058a 344 Gene3D G3DSA:3.40.190.10 284 344 5.7E-13 T 06-07-2017 SMD11_RS13150 7a549327626d0c333c82d77586ac058a 344 Gene3D G3DSA:3.40.190.100 157 283 4.0E-21 T 06-07-2017 SMD11_RS13150 7a549327626d0c333c82d77586ac058a 344 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 62 333 7.5E-47 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SMD11_RS20870 3e730e41c6ff8bb30735b0c073c52890 329 Pfam PF09594 Protein of unknown function (DUF2029) 32 265 3.9E-18 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 SMD11_RS00480 24b5640312e89722c173c7fb9127eee3 254 Gene3D G3DSA:1.10.260.40 8 70 2.9E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS00480 24b5640312e89722c173c7fb9127eee3 254 SUPERFAMILY SSF47413 7 73 1.35E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS22925 8e08c994678f6fce3793f8350e7951f9 156 SUPERFAMILY SSF46785 7 150 9.24E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS22925 8e08c994678f6fce3793f8350e7951f9 156 Pfam PF01047 MarR family 60 103 3.6E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS22925 8e08c994678f6fce3793f8350e7951f9 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 128 148 5.6E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS22925 8e08c994678f6fce3793f8350e7951f9 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 5.6E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS22925 8e08c994678f6fce3793f8350e7951f9 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 5.6E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS22925 8e08c994678f6fce3793f8350e7951f9 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 5.6E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS22925 8e08c994678f6fce3793f8350e7951f9 156 SMART SM00347 40 143 5.7E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS22925 8e08c994678f6fce3793f8350e7951f9 156 Gene3D G3DSA:1.10.10.10 12 150 1.2E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05215 e8220e4f2d89d30df3ba42c80f5519a2 87 SUPERFAMILY SSF46955 26 81 2.38E-7 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS05215 e8220e4f2d89d30df3ba42c80f5519a2 87 Gene3D G3DSA:1.10.10.10 29 82 1.3E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05215 e8220e4f2d89d30df3ba42c80f5519a2 87 Pfam PF12728 Helix-turn-helix domain 26 80 5.0E-8 T 06-07-2017 SMD11_RS18040 40f30e85b1c8112a4550359203329a46 496 Gene3D G3DSA:1.20.1250.20 282 471 3.9E-16 T 06-07-2017 SMD11_RS18040 40f30e85b1c8112a4550359203329a46 496 Pfam PF00083 Sugar (and other) transporter 73 481 8.0E-43 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMD11_RS18040 40f30e85b1c8112a4550359203329a46 496 SUPERFAMILY SSF103473 19 479 8.89E-69 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS18040 40f30e85b1c8112a4550359203329a46 496 Gene3D G3DSA:1.20.1250.20 44 231 4.0E-25 T 06-07-2017 SMD11_RS14210 9dd9c8f41193e96617a0938c5e417b7d 175 SUPERFAMILY SSF69635 4 129 3.4E-33 T 06-07-2017 SMD11_RS14210 9dd9c8f41193e96617a0938c5e417b7d 175 Pfam PF10722 Putative bacterial sensory transduction regulator 7 126 1.1E-20 T 06-07-2017 IPR019660 Putative sensory transduction regulator YbjN SMD11_RS14210 9dd9c8f41193e96617a0938c5e417b7d 175 Gene3D G3DSA:3.30.1460.10 7 137 2.8E-16 T 06-07-2017 SMD11_RS00610 d55db373fe93ab8259cf8095799450d1 334 SUPERFAMILY SSF55729 131 264 1.99E-10 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS00610 d55db373fe93ab8259cf8095799450d1 334 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 16 315 1.6E-61 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal SMD11_RS18300 0dafdc313c2d5ca0eef7ce7e004fe00c 157 SUPERFAMILY SSF55874 55 137 5.86E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS18300 0dafdc313c2d5ca0eef7ce7e004fe00c 157 Gene3D G3DSA:3.30.565.10 57 128 2.4E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS18300 0dafdc313c2d5ca0eef7ce7e004fe00c 157 Pfam PF13581 Histidine kinase-like ATPase domain 42 131 1.2E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS19205 fe14328e21de53936ed7ca67f410f76c 538 Pfam PF07690 Major Facilitator Superfamily 35 426 3.5E-52 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS19205 fe14328e21de53936ed7ca67f410f76c 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 33 57 1.2E-5 T 06-07-2017 SMD11_RS19205 fe14328e21de53936ed7ca67f410f76c 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 93 115 1.2E-5 T 06-07-2017 SMD11_RS19205 fe14328e21de53936ed7ca67f410f76c 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 155 179 1.2E-5 T 06-07-2017 SMD11_RS19205 fe14328e21de53936ed7ca67f410f76c 538 SUPERFAMILY SSF103473 264 436 1.28E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS19205 fe14328e21de53936ed7ca67f410f76c 538 SUPERFAMILY SSF103473 21 214 1.28E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS19205 fe14328e21de53936ed7ca67f410f76c 538 SUPERFAMILY SSF103473 478 502 1.28E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS19205 fe14328e21de53936ed7ca67f410f76c 538 Gene3D G3DSA:1.20.1250.20 477 512 1.5E-20 T 06-07-2017 SMD11_RS19205 fe14328e21de53936ed7ca67f410f76c 538 Gene3D G3DSA:1.20.1250.20 31 208 3.1E-26 T 06-07-2017 SMD11_RS19205 fe14328e21de53936ed7ca67f410f76c 538 Gene3D G3DSA:1.20.1250.20 278 434 1.5E-20 T 06-07-2017 SMD11_RS21985 dec906ca1d46bab4846c751628d8b6de 324 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS21985 dec906ca1d46bab4846c751628d8b6de 324 SMART SM00382 40 223 2.5E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS21985 dec906ca1d46bab4846c751628d8b6de 324 Pfam PF00005 ABC transporter 31 174 1.2E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS21985 dec906ca1d46bab4846c751628d8b6de 324 Gene3D G3DSA:3.40.50.300 13 235 1.8E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21985 dec906ca1d46bab4846c751628d8b6de 324 SUPERFAMILY SSF52540 16 234 5.54E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS21985 dec906ca1d46bab4846c751628d8b6de 324 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 23 315 7.1E-95 T 06-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 SMD11_RS30675 3a92106c154ad3d79030a4045f1112e0 327 Gene3D G3DSA:3.30.420.150 131 308 8.7E-43 T 06-07-2017 SMD11_RS30675 3a92106c154ad3d79030a4045f1112e0 327 Pfam PF02541 Ppx/GppA phosphatase family 29 304 5.4E-54 T 06-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 SMD11_RS30675 3a92106c154ad3d79030a4045f1112e0 327 Gene3D G3DSA:3.30.420.40 1 126 1.4E-34 T 06-07-2017 SMD11_RS30675 3a92106c154ad3d79030a4045f1112e0 327 SUPERFAMILY SSF53067 1 126 5.5E-25 T 06-07-2017 SMD11_RS30675 3a92106c154ad3d79030a4045f1112e0 327 SUPERFAMILY SSF53067 133 308 1.49E-30 T 06-07-2017 SMD11_RS28340 244ff46f43f76e19cfafaa69e53709af 495 SUPERFAMILY SSF55874 231 350 4.85E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS28340 244ff46f43f76e19cfafaa69e53709af 495 Gene3D G3DSA:3.30.565.10 233 354 3.8E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS05180 f0e546981c396921209039a41392c5f2 295 Pfam PF01636 Phosphotransferase enzyme family 40 235 2.9E-21 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase SMD11_RS05180 f0e546981c396921209039a41392c5f2 295 Gene3D G3DSA:3.90.1200.10 96 272 8.7E-20 T 06-07-2017 SMD11_RS05180 f0e546981c396921209039a41392c5f2 295 SUPERFAMILY SSF56112 11 267 5.54E-35 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS30955 3bc305f08ea46bdfe8dd0ca134645816 427 Gene3D G3DSA:1.20.1250.20 261 414 5.3E-14 T 06-07-2017 SMD11_RS30955 3bc305f08ea46bdfe8dd0ca134645816 427 Pfam PF05977 Transmembrane secretion effector 22 410 3.6E-46 T 06-07-2017 IPR010290 Transmembrane secretion effector SMD11_RS30955 3bc305f08ea46bdfe8dd0ca134645816 427 Gene3D G3DSA:1.20.1250.20 35 211 4.0E-17 T 06-07-2017 SMD11_RS30955 3bc305f08ea46bdfe8dd0ca134645816 427 SUPERFAMILY SSF103473 32 419 8.24E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS13085 26acf2424c80b3fdcf3c6cffd4ed8784 261 SUPERFAMILY SSF53474 7 258 1.59E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS13085 26acf2424c80b3fdcf3c6cffd4ed8784 261 Gene3D G3DSA:3.40.50.1820 8 259 1.4E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS13085 26acf2424c80b3fdcf3c6cffd4ed8784 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 43 58 9.5E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS13085 26acf2424c80b3fdcf3c6cffd4ed8784 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 9.5E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS13085 26acf2424c80b3fdcf3c6cffd4ed8784 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 9.5E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS13085 26acf2424c80b3fdcf3c6cffd4ed8784 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 203 217 9.5E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS13085 26acf2424c80b3fdcf3c6cffd4ed8784 261 Pfam PF00561 alpha/beta hydrolase fold 19 148 1.3E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS18885 2c4f8b674ab52a1164426de1ebf1b766 214 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 7 208 2.6E-90 T 06-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18885 2c4f8b674ab52a1164426de1ebf1b766 214 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 5 211 39.984 T 06-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18885 2c4f8b674ab52a1164426de1ebf1b766 214 Gene3D G3DSA:2.40.30.10 162 211 4.4E-12 T 06-07-2017 SMD11_RS18885 2c4f8b674ab52a1164426de1ebf1b766 214 Gene3D G3DSA:2.40.30.10 7 36 4.4E-12 T 06-07-2017 SMD11_RS18885 2c4f8b674ab52a1164426de1ebf1b766 214 Gene3D G3DSA:4.10.960.10 80 161 1.1E-33 T 06-07-2017 SMD11_RS18885 2c4f8b674ab52a1164426de1ebf1b766 214 Pfam PF00297 Ribosomal protein L3 99 186 2.7E-15 T 06-07-2017 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18885 2c4f8b674ab52a1164426de1ebf1b766 214 SUPERFAMILY SSF50447 5 212 2.03E-80 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS18885 2c4f8b674ab52a1164426de1ebf1b766 214 ProSitePatterns PS00474 Ribosomal protein L3 signature. 105 128 - T 06-07-2017 IPR019926 Ribosomal protein L3, conserved site SMD11_RS26110 b6e4295fef591d4675c8601a6c909cbc 399 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 212 342 7.0E-11 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS26110 b6e4295fef591d4675c8601a6c909cbc 399 SMART SM00382 208 345 7.8E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS26110 b6e4295fef591d4675c8601a6c909cbc 399 Gene3D G3DSA:3.40.50.300 210 336 7.5E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS26110 b6e4295fef591d4675c8601a6c909cbc 399 SUPERFAMILY SSF52540 208 345 4.71E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS25570 f1f95c6ffb455fe566223d50850b9fc6 256 PIRSF PIRSF000094 2 256 2.2E-79 T 06-07-2017 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 SMD11_RS25570 f1f95c6ffb455fe566223d50850b9fc6 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 252 4.3E-63 T 06-07-2017 SMD11_RS25570 f1f95c6ffb455fe566223d50850b9fc6 256 Gene3D G3DSA:3.40.50.720 3 255 2.8E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS25570 f1f95c6ffb455fe566223d50850b9fc6 256 SUPERFAMILY SSF51735 7 254 8.71E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18270 2bb300c9e140ed1d92d3f542f5f08ef2 95 SUPERFAMILY SSF52833 16 94 1.28E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS18270 2bb300c9e140ed1d92d3f542f5f08ef2 95 Pfam PF05768 Glutaredoxin-like domain (DUF836) 20 93 2.4E-20 T 06-07-2017 IPR008554 Glutaredoxin-like SMD11_RS18270 2bb300c9e140ed1d92d3f542f5f08ef2 95 Gene3D G3DSA:3.40.30.10 20 94 1.9E-26 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS31165 5305982e227e0d9246df7526432dbae0 240 Pfam PF14273 Domain of unknown function (DUF4360) 58 237 2.2E-68 T 06-07-2017 IPR025649 Protein of unknown function DUF4360 SMD11_RS00565 5fe06a8d824936c03ad6b93dc5aa97b2 186 Pfam PF05685 Putative restriction endonuclease 19 150 2.2E-20 T 06-07-2017 IPR008538 Domain of unknown function DUF820 SMD11_RS00565 5fe06a8d824936c03ad6b93dc5aa97b2 186 SUPERFAMILY SSF52980 22 143 9.12E-15 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD11_RS00565 5fe06a8d824936c03ad6b93dc5aa97b2 186 Gene3D G3DSA:3.90.1570.10 19 143 2.1E-17 T 06-07-2017 IPR012296 Nuclease, putative, TT1808 SMD11_RS19340 58289e772048d44f677547e6c312154b 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 118 204 5.0E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 SMD11_RS19340 58289e772048d44f677547e6c312154b 385 SUPERFAMILY SSF56645 2 238 9.56E-58 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS19340 58289e772048d44f677547e6c312154b 385 Gene3D G3DSA:1.20.140.10 216 383 1.4E-21 T 06-07-2017 SMD11_RS19340 58289e772048d44f677547e6c312154b 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 226 377 1.1E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS19340 58289e772048d44f677547e6c312154b 385 SUPERFAMILY SSF47203 226 379 1.48E-17 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS19340 58289e772048d44f677547e6c312154b 385 Gene3D G3DSA:2.40.110.10 117 215 2.4E-30 T 06-07-2017 SMD11_RS19340 58289e772048d44f677547e6c312154b 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 114 4.4E-16 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS19340 58289e772048d44f677547e6c312154b 385 Gene3D G3DSA:1.10.540.10 2 115 8.8E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS34130 8deb156325c0d918024769b9b9d434e5 457 Gene3D G3DSA:3.50.50.60 11 201 2.5E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS34130 8deb156325c0d918024769b9b9d434e5 457 Gene3D G3DSA:3.50.50.60 313 350 2.5E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS34130 8deb156325c0d918024769b9b9d434e5 457 SUPERFAMILY SSF51905 8 197 4.04E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS34130 8deb156325c0d918024769b9b9d434e5 457 SUPERFAMILY SSF51905 310 404 4.04E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS29690 e3d23f725f5d3963fa5856f59b3777c1 433 Pfam PF13458 Periplasmic binding protein 25 406 1.4E-33 T 06-07-2017 IPR028081 Leucine-binding protein domain SMD11_RS29690 e3d23f725f5d3963fa5856f59b3777c1 433 Gene3D G3DSA:3.40.50.2300 167 267 3.4E-7 T 06-07-2017 SMD11_RS29690 e3d23f725f5d3963fa5856f59b3777c1 433 Gene3D G3DSA:3.40.50.2300 20 154 7.9E-17 T 06-07-2017 SMD11_RS29690 e3d23f725f5d3963fa5856f59b3777c1 433 Gene3D G3DSA:3.40.50.2300 325 387 7.9E-17 T 06-07-2017 SMD11_RS29690 e3d23f725f5d3963fa5856f59b3777c1 433 SUPERFAMILY SSF53822 22 260 6.39E-35 T 06-07-2017 IPR028082 Periplasmic binding protein-like I SMD11_RS29690 e3d23f725f5d3963fa5856f59b3777c1 433 SUPERFAMILY SSF53822 289 404 6.39E-35 T 06-07-2017 IPR028082 Periplasmic binding protein-like I SMD11_RS24500 fb6b5b86aa253ad349615fceff64e5ae 354 ProSitePatterns PS01348 MraY family signature 2. 174 185 - T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD11_RS24500 fb6b5b86aa253ad349615fceff64e5ae 354 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD11_RS24500 fb6b5b86aa253ad349615fceff64e5ae 354 Pfam PF00953 Glycosyl transferase family 4 82 273 1.3E-37 T 06-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 SMD11_RS24500 fb6b5b86aa253ad349615fceff64e5ae 354 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 19 343 5.7E-97 T 06-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD11_RS24500 fb6b5b86aa253ad349615fceff64e5ae 354 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 2.8E-5 T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD11_RS24500 fb6b5b86aa253ad349615fceff64e5ae 354 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 347 23.806 T 06-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD11_RS23570 6be5b717abe626795386db555379eb06 354 SUPERFAMILY SSF53187 105 322 7.22E-29 T 06-07-2017 SMD11_RS23570 6be5b717abe626795386db555379eb06 354 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 108 319 3.6E-33 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 SMD11_RS23570 6be5b717abe626795386db555379eb06 354 Gene3D G3DSA:3.40.630.40 105 322 4.9E-33 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 SMD11_RS23570 6be5b717abe626795386db555379eb06 354 SMART SM00646 191 319 2.4E-14 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 SMD11_RS01865 763d4a4848419226512838fb1ca88600 274 SUPERFAMILY SSF53335 4 236 2.3E-62 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS01865 763d4a4848419226512838fb1ca88600 274 Pfam PF04072 Leucine carboxyl methyltransferase 9 175 5.7E-45 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 SMD11_RS01865 763d4a4848419226512838fb1ca88600 274 Gene3D G3DSA:3.40.50.150 4 214 1.2E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS01865 763d4a4848419226512838fb1ca88600 274 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 6 242 1.1E-64 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 SMD11_RS32550 f3ac2da816eafa6e832d467e827e40fa 300 Pfam PF08241 Methyltransferase domain 94 188 7.4E-19 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS32550 f3ac2da816eafa6e832d467e827e40fa 300 SUPERFAMILY SSF53335 60 255 5.78E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS32550 f3ac2da816eafa6e832d467e827e40fa 300 Gene3D G3DSA:3.40.50.150 60 272 1.4E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS27165 a04faf0a969b914e4673d0cbb6f5cab6 304 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 19 304 5.7E-143 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD11_RS27165 a04faf0a969b914e4673d0cbb6f5cab6 304 SUPERFAMILY SSF51366 28 273 2.4E-63 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMD11_RS27165 a04faf0a969b914e4673d0cbb6f5cab6 304 Pfam PF01680 SOR/SNZ family 17 222 1.0E-107 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD11_RS27165 a04faf0a969b914e4673d0cbb6f5cab6 304 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 14 304 52.271 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD11_RS27165 a04faf0a969b914e4673d0cbb6f5cab6 304 Gene3D G3DSA:3.20.20.70 34 170 8.9E-47 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS27165 a04faf0a969b914e4673d0cbb6f5cab6 304 Gene3D G3DSA:3.20.20.70 202 288 8.9E-47 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS27165 a04faf0a969b914e4673d0cbb6f5cab6 304 ProSitePatterns PS01235 PdxS/SNZ family signature. 215 233 - T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD11_RS27165 a04faf0a969b914e4673d0cbb6f5cab6 304 PIRSF PIRSF029271 6 304 1.1E-151 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 SMD11_RS05550 baf29157ce341321f46d9a0fb9bc68fc 318 Pfam PF12833 Helix-turn-helix domain 234 312 1.7E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS05550 baf29157ce341321f46d9a0fb9bc68fc 318 SUPERFAMILY SSF46689 212 262 2.12E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS05550 baf29157ce341321f46d9a0fb9bc68fc 318 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 265 307 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SMD11_RS05550 baf29157ce341321f46d9a0fb9bc68fc 318 Gene3D G3DSA:1.10.10.60 207 265 2.5E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS05550 baf29157ce341321f46d9a0fb9bc68fc 318 SMART SM00342 228 311 9.8E-30 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SMD11_RS05550 baf29157ce341321f46d9a0fb9bc68fc 318 SUPERFAMILY SSF52317 7 194 2.29E-41 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS05550 baf29157ce341321f46d9a0fb9bc68fc 318 Gene3D G3DSA:3.40.50.880 8 191 2.7E-46 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS05550 baf29157ce341321f46d9a0fb9bc68fc 318 Pfam PF01965 DJ-1/PfpI family 8 172 4.6E-22 T 06-07-2017 IPR002818 DJ-1/PfpI SMD11_RS05550 baf29157ce341321f46d9a0fb9bc68fc 318 Gene3D G3DSA:1.10.10.60 266 313 2.5E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS05550 baf29157ce341321f46d9a0fb9bc68fc 318 SUPERFAMILY SSF46689 265 314 1.34E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS07555 7e799d51d44c09d4d1cd108d8ff893dc 245 Gene3D G3DSA:2.130.10.130 29 206 1.7E-15 T 06-07-2017 SMD11_RS07555 7e799d51d44c09d4d1cd108d8ff893dc 245 SUPERFAMILY SSF69318 22 229 2.01E-21 T 06-07-2017 SMD11_RS07555 7e799d51d44c09d4d1cd108d8ff893dc 245 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 36 100 8.3E-11 T 06-07-2017 SMD11_RS07555 7e799d51d44c09d4d1cd108d8ff893dc 245 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 144 205 8.3E-11 T 06-07-2017 SMD11_RS22630 3260fa0b5be49ac47c7b3fff5fad9a5d 399 Gene3D G3DSA:3.20.20.70 9 344 3.6E-63 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS22630 3260fa0b5be49ac47c7b3fff5fad9a5d 399 Pfam PF03060 Nitronate monooxygenase 10 352 1.4E-102 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SMD11_RS22630 3260fa0b5be49ac47c7b3fff5fad9a5d 399 SUPERFAMILY SSF51412 11 358 1.98E-55 T 06-07-2017 SMD11_RS28870 04c333e7e3f55d0bd002dea2843b1c9b 242 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 7 202 1.2E-37 T 06-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 SMD11_RS28870 04c333e7e3f55d0bd002dea2843b1c9b 242 Gene3D G3DSA:3.40.50.880 22 212 8.1E-19 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS28870 04c333e7e3f55d0bd002dea2843b1c9b 242 SUPERFAMILY SSF52317 23 214 7.43E-19 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS00645 1744d2637915fa35762d11384f5d7289 191 Pfam PF03992 Antibiotic biosynthesis monooxygenase 128 169 1.8E-5 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain SMD11_RS00645 1744d2637915fa35762d11384f5d7289 191 SUPERFAMILY SSF54909 129 172 5.1E-5 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS00645 1744d2637915fa35762d11384f5d7289 191 Gene3D G3DSA:3.30.70.900 9 110 1.8E-10 T 06-07-2017 SMD11_RS00645 1744d2637915fa35762d11384f5d7289 191 Gene3D G3DSA:3.30.70.900 129 172 8.9E-7 T 06-07-2017 SMD11_RS28455 0f00920c5aa13f039b5c9d70e6ed4896 150 Gene3D G3DSA:3.10.129.10 10 149 1.5E-38 T 06-07-2017 IPR029069 HotDog domain SMD11_RS28455 0f00920c5aa13f039b5c9d70e6ed4896 150 Pfam PF14539 Domain of unknown function (DUF4442) 11 145 9.2E-27 T 06-07-2017 IPR027961 Protein of unknown function DUF4442 SMD11_RS28455 0f00920c5aa13f039b5c9d70e6ed4896 150 SUPERFAMILY SSF54637 4 148 5.33E-19 T 06-07-2017 IPR029069 HotDog domain SMD11_RS32445 d402333956cce88e5397a3e0e77b4111 367 SUPERFAMILY SSF56801 52 360 1.7E-27 T 06-07-2017 SMD11_RS32445 d402333956cce88e5397a3e0e77b4111 367 Gene3D G3DSA:3.30.300.30 271 358 9.7E-5 T 06-07-2017 SMD11_RS32445 d402333956cce88e5397a3e0e77b4111 367 Gene3D G3DSA:3.40.50.980 54 204 1.2E-6 T 06-07-2017 SMD11_RS32445 d402333956cce88e5397a3e0e77b4111 367 Pfam PF00501 AMP-binding enzyme 56 204 9.6E-8 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS18710 16fa041d553b45ca77706aef13b14ed4 201 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 47 192 3.8E-32 T 06-07-2017 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS17420 a646ee2f20c87acb0925f432a3404cae 555 Gene3D G3DSA:3.30.465.10 143 256 8.1E-7 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS17420 a646ee2f20c87acb0925f432a3404cae 555 Pfam PF01565 FAD binding domain 85 220 6.6E-19 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD11_RS17420 a646ee2f20c87acb0925f432a3404cae 555 Gene3D G3DSA:3.30.43.10 93 131 6.3E-4 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS17420 a646ee2f20c87acb0925f432a3404cae 555 SUPERFAMILY SSF56176 60 257 2.99E-33 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS17420 a646ee2f20c87acb0925f432a3404cae 555 Pfam PF08031 Berberine and berberine like 499 551 1.6E-17 T 06-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 SMD11_RS32590 4c88e6fe0f7d8389478f54fd6e273e53 537 Gene3D G3DSA:3.40.50.980 173 317 1.3E-16 T 06-07-2017 SMD11_RS32590 4c88e6fe0f7d8389478f54fd6e273e53 537 Gene3D G3DSA:3.30.300.30 420 514 1.5E-25 T 06-07-2017 SMD11_RS32590 4c88e6fe0f7d8389478f54fd6e273e53 537 Gene3D G3DSA:3.40.50.980 10 172 1.3E-11 T 06-07-2017 SMD11_RS32590 4c88e6fe0f7d8389478f54fd6e273e53 537 SUPERFAMILY SSF56801 5 520 1.44E-82 T 06-07-2017 SMD11_RS32590 4c88e6fe0f7d8389478f54fd6e273e53 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 508 1.6E-13 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS32590 4c88e6fe0f7d8389478f54fd6e273e53 537 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS32590 4c88e6fe0f7d8389478f54fd6e273e53 537 Pfam PF00501 AMP-binding enzyme 14 422 3.8E-39 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS32590 4c88e6fe0f7d8389478f54fd6e273e53 537 Gene3D G3DSA:2.30.38.10 345 416 5.8E-11 T 06-07-2017 SMD11_RS29155 271de3c44033d7cf33d3ad8e66e73c18 369 Gene3D G3DSA:3.90.1200.10 157 305 4.7E-11 T 06-07-2017 SMD11_RS29155 271de3c44033d7cf33d3ad8e66e73c18 369 SUPERFAMILY SSF56112 90 311 4.34E-24 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS29155 271de3c44033d7cf33d3ad8e66e73c18 369 Pfam PF01636 Phosphotransferase enzyme family 103 301 6.1E-16 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase SMD11_RS18610 2fbf023d2bd649c847ef077608534726 228 Gene3D G3DSA:1.10.3630.10 5 204 1.5E-22 T 06-07-2017 SMD11_RS18610 2fbf023d2bd649c847ef077608534726 228 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 10 204 3.9E-35 T 06-07-2017 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 SMD11_RS26325 b2a04b94fa697dc04a72d0cf1cbc7ab0 299 Pfam PF03777 Small secreted domain (DUF320) 92 147 3.3E-22 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD11_RS26325 b2a04b94fa697dc04a72d0cf1cbc7ab0 299 Pfam PF03777 Small secreted domain (DUF320) 24 79 1.2E-27 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD11_RS31560 0d8833b235c82e7968dd640df1fae3d5 423 Pfam PF00501 AMP-binding enzyme 64 268 8.1E-7 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS31560 0d8833b235c82e7968dd640df1fae3d5 423 SUPERFAMILY SSF56801 17 353 3.53E-22 T 06-07-2017 SMD11_RS31560 0d8833b235c82e7968dd640df1fae3d5 423 Gene3D G3DSA:3.40.50.980 64 208 3.4E-4 T 06-07-2017 SMD11_RS10185 c4e0ba2f6df43a63201269127123c760 284 Pfam PF13560 Helix-turn-helix domain 13 70 4.1E-10 T 06-07-2017 SMD11_RS10185 c4e0ba2f6df43a63201269127123c760 284 SMART SM00530 17 72 1.4E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS10185 c4e0ba2f6df43a63201269127123c760 284 Gene3D G3DSA:1.10.260.40 12 74 7.4E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS10185 c4e0ba2f6df43a63201269127123c760 284 SUPERFAMILY SSF47413 13 73 3.84E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS11040 746af911159695c91d331a8cd34d3ac1 245 SUPERFAMILY SSF52172 17 138 6.83E-41 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS11040 746af911159695c91d331a8cd34d3ac1 245 SUPERFAMILY SSF46894 146 241 2.13E-27 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS11040 746af911159695c91d331a8cd34d3ac1 245 Gene3D G3DSA:1.10.10.10 147 242 2.7E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11040 746af911159695c91d331a8cd34d3ac1 245 Gene3D G3DSA:3.40.50.2300 17 137 2.7E-39 T 06-07-2017 SMD11_RS11040 746af911159695c91d331a8cd34d3ac1 245 Pfam PF00072 Response regulator receiver domain 21 129 1.2E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS11040 746af911159695c91d331a8cd34d3ac1 245 SMART SM00862 169 240 1.8E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS11040 746af911159695c91d331a8cd34d3ac1 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 169 240 5.3E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS11040 746af911159695c91d331a8cd34d3ac1 245 SMART SM00448 19 129 1.8E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS18740 f4a3c7db27c32713f644737de84b63e6 130 PIRSF PIRSF028777 1 130 2.5E-53 T 06-07-2017 IPR031308 Uncharacterised conserved protein UCP028777 SMD11_RS18740 f4a3c7db27c32713f644737de84b63e6 130 Pfam PF03733 Inner membrane component domain 4 54 1.8E-18 T 06-07-2017 IPR005185 Inner membrane component domain SMD11_RS18740 f4a3c7db27c32713f644737de84b63e6 130 Pfam PF03733 Inner membrane component domain 68 118 3.4E-18 T 06-07-2017 IPR005185 Inner membrane component domain SMD11_RS17310 0e1d62641ef6717badb5ecba3592d88b 150 Pfam PF07179 SseB protein N-terminal domain 72 138 2.4E-7 T 06-07-2017 IPR009839 SseB protein N-terminal domain SMD11_RS12390 97dc069ab98213bc230465609dbc501e 430 SMART SM01119 319 417 5.8E-34 T 06-07-2017 IPR026956 D-serine dehydratase-like domain SMD11_RS12390 97dc069ab98213bc230465609dbc501e 430 Pfam PF01168 Alanine racemase, N-terminal domain 59 262 2.1E-12 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS12390 97dc069ab98213bc230465609dbc501e 430 SUPERFAMILY SSF51419 61 273 1.4E-22 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS12390 97dc069ab98213bc230465609dbc501e 430 Gene3D G3DSA:3.20.20.10 147 269 1.0E-10 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS12390 97dc069ab98213bc230465609dbc501e 430 Pfam PF14031 Putative serine dehydratase domain 319 414 4.6E-16 T 06-07-2017 IPR026956 D-serine dehydratase-like domain SMD11_RS28980 bf2593d2ed00ddb1ea0a3488c5ce238f 264 SUPERFAMILY SSF48317 6 209 3.14E-32 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS28980 bf2593d2ed00ddb1ea0a3488c5ce238f 264 Pfam PF01569 PAP2 superfamily 97 200 3.5E-20 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS28980 bf2593d2ed00ddb1ea0a3488c5ce238f 264 SMART SM00014 87 198 9.2E-16 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS28980 bf2593d2ed00ddb1ea0a3488c5ce238f 264 Gene3D G3DSA:1.20.144.10 18 199 1.3E-26 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS17810 e066a062b949b11f865cbce9cb095fcc 815 Gene3D G3DSA:3.90.550.10 9 137 2.9E-23 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS17810 e066a062b949b11f865cbce9cb095fcc 815 Pfam PF00535 Glycosyl transferase family 2 11 148 4.0E-26 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD11_RS17810 e066a062b949b11f865cbce9cb095fcc 815 SUPERFAMILY SSF53448 7 250 1.55E-37 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS06850 1f1e0fc4d41b2684a0acc523d8427cf5 336 Gene3D G3DSA:3.40.50.2300 49 171 3.1E-30 T 06-07-2017 SMD11_RS06850 1f1e0fc4d41b2684a0acc523d8427cf5 336 SUPERFAMILY SSF53822 54 325 5.18E-53 T 06-07-2017 IPR028082 Periplasmic binding protein-like I SMD11_RS06850 1f1e0fc4d41b2684a0acc523d8427cf5 336 Pfam PF13407 Periplasmic binding protein domain 55 299 1.6E-42 T 06-07-2017 IPR025997 Periplasmic binding protein SMD11_RS06850 1f1e0fc4d41b2684a0acc523d8427cf5 336 Gene3D G3DSA:3.40.50.2300 172 297 6.7E-19 T 06-07-2017 SMD11_RS01555 67ba9a55563c102f679352d2c67249d5 241 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 136 146 - T 06-07-2017 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 SMD11_RS01555 67ba9a55563c102f679352d2c67249d5 241 SUPERFAMILY SSF52799 7 240 8.84E-48 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like SMD11_RS01555 67ba9a55563c102f679352d2c67249d5 241 Pfam PF13350 Tyrosine phosphatase family 6 240 1.4E-66 T 06-07-2017 IPR026893 Tyrosine/serine-protein phosphatase IphP-type SMD11_RS01555 67ba9a55563c102f679352d2c67249d5 241 Gene3D G3DSA:3.90.190.10 8 171 1.9E-22 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like SMD11_RS11975 da6983a40224e106b14649da7a0104df 358 SMART SM00382 48 247 2.6E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS11975 da6983a40224e106b14649da7a0104df 358 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 335 1.1E-20 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS11975 da6983a40224e106b14649da7a0104df 358 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS11975 da6983a40224e106b14649da7a0104df 358 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 311 2.8E-17 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS11975 da6983a40224e106b14649da7a0104df 358 SUPERFAMILY SSF52540 20 268 4.14E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11975 da6983a40224e106b14649da7a0104df 358 Pfam PF00005 ABC transporter 40 197 3.9E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS11975 da6983a40224e106b14649da7a0104df 358 Gene3D G3DSA:3.40.50.300 18 270 9.1E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10105 3b07443a252a32cad46466caabeb1a58 701 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 2 700 2.4E-212 T 06-07-2017 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 SMD11_RS10105 3b07443a252a32cad46466caabeb1a58 701 Pfam PF05506 Domain of unknown function (DUF756) 610 691 4.8E-10 T 06-07-2017 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 SMD11_RS10105 3b07443a252a32cad46466caabeb1a58 701 Pfam PF05506 Domain of unknown function (DUF756) 514 597 1.9E-15 T 06-07-2017 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 SMD11_RS10105 3b07443a252a32cad46466caabeb1a58 701 Pfam PF04185 Phosphoesterase family 49 262 2.3E-46 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 SMD11_RS10105 3b07443a252a32cad46466caabeb1a58 701 Pfam PF04185 Phosphoesterase family 308 451 1.8E-46 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 SMD11_RS19045 ad70efaac9c4b80efddbc3495f959d52 732 Gene3D G3DSA:3.40.50.2000 208 366 2.6E-22 T 06-07-2017 SMD11_RS19045 ad70efaac9c4b80efddbc3495f959d52 732 Pfam PF00534 Glycosyl transferases group 1 207 367 4.0E-33 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 SMD11_RS19045 ad70efaac9c4b80efddbc3495f959d52 732 SUPERFAMILY SSF53756 84 387 3.14E-68 T 06-07-2017 SMD11_RS19045 ad70efaac9c4b80efddbc3495f959d52 732 SUPERFAMILY SSF53756 2 57 3.14E-68 T 06-07-2017 SMD11_RS32190 02eee495773c0e89ff94905b4a497856 54 SUPERFAMILY SSF53927 17 53 1.56E-7 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 SMD11_RS32190 02eee495773c0e89ff94905b4a497856 54 Gene3D G3DSA:3.40.140.10 17 53 1.2E-6 T 06-07-2017 SMD11_RS13565 289a4a9accc6253a100b35975cb9e659 225 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 27 200 7.1E-24 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD11_RS13565 289a4a9accc6253a100b35975cb9e659 225 SMART SM00943 27 208 1.5E-30 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD11_RS25360 2fd42b7014e7c61253e87f670a667ba3 184 Gene3D G3DSA:3.30.420.180 57 180 6.6E-31 T 06-07-2017 IPR002750 CobE/GbiG C-terminal domain GO:0009236 SMD11_RS25360 2fd42b7014e7c61253e87f670a667ba3 184 SUPERFAMILY SSF159664 57 180 1.29E-30 T 06-07-2017 IPR002750 CobE/GbiG C-terminal domain GO:0009236 SMD11_RS25360 2fd42b7014e7c61253e87f670a667ba3 184 Pfam PF01890 Cobalamin synthesis G C-terminus 58 179 2.4E-27 T 06-07-2017 IPR002750 CobE/GbiG C-terminal domain GO:0009236 SMD11_RS09595 73f1f3e0d5a59ac38558564618cd0d47 198 Pfam PF05239 PRC-barrel domain 94 166 8.6E-12 T 06-07-2017 IPR027275 PRC-barrel domain SMD11_RS09595 73f1f3e0d5a59ac38558564618cd0d47 198 Gene3D G3DSA:2.40.30.60 3 83 3.1E-21 T 06-07-2017 IPR002676 RimM protein GO:0006364 SMD11_RS09595 73f1f3e0d5a59ac38558564618cd0d47 198 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 166 23.415 T 06-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 SMD11_RS09595 73f1f3e0d5a59ac38558564618cd0d47 198 Pfam PF01782 RimM N-terminal domain 4 83 3.4E-22 T 06-07-2017 IPR002676 RimM protein GO:0006364 SMD11_RS09595 73f1f3e0d5a59ac38558564618cd0d47 198 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 166 5.7E-43 T 06-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 SMD11_RS09595 73f1f3e0d5a59ac38558564618cd0d47 198 SUPERFAMILY SSF50346 96 166 1.14E-18 T 06-07-2017 IPR011033 PRC-barrel-like SMD11_RS09595 73f1f3e0d5a59ac38558564618cd0d47 198 Gene3D G3DSA:2.30.30.240 96 166 2.3E-20 T 06-07-2017 SMD11_RS09595 73f1f3e0d5a59ac38558564618cd0d47 198 SUPERFAMILY SSF50447 3 85 1.41E-18 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain SMD11_RS00585 10632f2b6f1177f6b12f9b8573426ee1 343 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 13 337 61.175 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS00585 10632f2b6f1177f6b12f9b8573426ee1 343 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 196 7.6E-24 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS00585 10632f2b6f1177f6b12f9b8573426ee1 343 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 15 336 3.4E-96 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS00585 10632f2b6f1177f6b12f9b8573426ee1 343 SUPERFAMILY SSF53901 13 337 7.34E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00585 10632f2b6f1177f6b12f9b8573426ee1 343 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 248 337 6.8E-30 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS00585 10632f2b6f1177f6b12f9b8573426ee1 343 Gene3D G3DSA:3.40.47.10 15 170 1.5E-50 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS00585 10632f2b6f1177f6b12f9b8573426ee1 343 Gene3D G3DSA:3.40.47.10 171 338 2.3E-44 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS02745 22ef51a0f5e03ef07c525997f87ad825 82 Gene3D G3DSA:3.40.50.2300 1 46 1.8E-11 T 06-07-2017 SMD11_RS02745 22ef51a0f5e03ef07c525997f87ad825 82 Pfam PF00072 Response regulator receiver domain 1 47 2.4E-7 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS02745 22ef51a0f5e03ef07c525997f87ad825 82 SUPERFAMILY SSF52172 2 48 6.4E-12 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS24630 709c6c51f985f9d99a4da241689e35ed 444 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 30 434 6.0E-118 T 06-07-2017 IPR018721 Protein of unknown function DUF2252 SMD11_RS24630 709c6c51f985f9d99a4da241689e35ed 444 Gene3D G3DSA:3.90.1200.10 73 206 8.2E-7 T 06-07-2017 SMD11_RS24630 709c6c51f985f9d99a4da241689e35ed 444 SUPERFAMILY SSF56112 38 198 1.51E-8 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS13515 97159bad4167e6878a6b778c50c4d982 286 Pfam PF14247 Putative metallopeptidase 67 280 2.6E-44 T 06-07-2017 IPR025644 Putative metallopeptidase SMD11_RS28790 22e5e6dda59fd510ab51aa055c33c927 289 Gene3D G3DSA:1.10.260.40 7 69 2.6E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS28790 22e5e6dda59fd510ab51aa055c33c927 289 SMART SM00530 15 70 1.2E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS28790 22e5e6dda59fd510ab51aa055c33c927 289 SUPERFAMILY SSF47413 8 66 6.7E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS28790 22e5e6dda59fd510ab51aa055c33c927 289 Pfam PF13560 Helix-turn-helix domain 12 73 3.5E-15 T 06-07-2017 SMD11_RS15145 5626a80fbf813b3eb1d4b4f39ae85ea8 176 Gene3D G3DSA:1.10.10.10 103 164 1.8E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15145 5626a80fbf813b3eb1d4b4f39ae85ea8 176 SUPERFAMILY SSF88946 6 70 3.92E-6 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS15145 5626a80fbf813b3eb1d4b4f39ae85ea8 176 Gene3D G3DSA:1.10.1740.10 7 73 4.8E-5 T 06-07-2017 SMD11_RS15145 5626a80fbf813b3eb1d4b4f39ae85ea8 176 SUPERFAMILY SSF88659 104 163 1.59E-8 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS23380 b9d37299f442555391eac3b87774d752 219 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 82 108 1.2E-62 T 06-07-2017 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD11_RS23380 b9d37299f442555391eac3b87774d752 219 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 114 138 1.2E-62 T 06-07-2017 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD11_RS23380 b9d37299f442555391eac3b87774d752 219 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 139 163 1.2E-62 T 06-07-2017 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD11_RS23380 b9d37299f442555391eac3b87774d752 219 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 164 188 1.2E-62 T 06-07-2017 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD11_RS23380 b9d37299f442555391eac3b87774d752 219 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 191 205 1.2E-62 T 06-07-2017 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD11_RS23380 b9d37299f442555391eac3b87774d752 219 PIRSF PIRSF016573 1 218 4.3E-99 T 06-07-2017 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD11_RS23380 b9d37299f442555391eac3b87774d752 219 Gene3D G3DSA:3.40.390.10 77 204 1.7E-38 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD11_RS23380 b9d37299f442555391eac3b87774d752 219 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 76 206 1.7E-75 T 06-07-2017 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD11_RS23380 b9d37299f442555391eac3b87774d752 219 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 83 206 7.0E-60 T 06-07-2017 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 SMD11_RS23380 b9d37299f442555391eac3b87774d752 219 SUPERFAMILY SSF55486 77 203 2.59E-30 T 06-07-2017 SMD11_RS25220 6a4925d204eb493f9138ffd99cd24994 107 Gene3D G3DSA:2.102.10.10 2 105 1.4E-35 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS25220 6a4925d204eb493f9138ffd99cd24994 107 Pfam PF00355 Rieske [2Fe-2S] domain 6 91 9.1E-22 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS25220 6a4925d204eb493f9138ffd99cd24994 107 SUPERFAMILY SSF50022 4 105 1.23E-32 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS19360 84d3a4985ece158dc5df5c9b8d3d762c 460 SUPERFAMILY SSF103473 34 448 3.66E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS19360 84d3a4985ece158dc5df5c9b8d3d762c 460 Pfam PF07690 Major Facilitator Superfamily 52 312 7.8E-24 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS19360 84d3a4985ece158dc5df5c9b8d3d762c 460 Gene3D G3DSA:1.20.1250.20 43 231 8.9E-27 T 06-07-2017 SMD11_RS19360 84d3a4985ece158dc5df5c9b8d3d762c 460 Gene3D G3DSA:1.20.1250.20 265 449 6.7E-16 T 06-07-2017 SMD11_RS03570 6e4824b71a1c7d5293541c86729ed506 146 Pfam PF01047 MarR family 34 92 6.8E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS03570 6e4824b71a1c7d5293541c86729ed506 146 SMART SM00347 27 128 3.7E-24 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS03570 6e4824b71a1c7d5293541c86729ed506 146 Gene3D G3DSA:1.10.10.10 5 140 9.4E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03570 6e4824b71a1c7d5293541c86729ed506 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 1.0E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS03570 6e4824b71a1c7d5293541c86729ed506 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.0E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS03570 6e4824b71a1c7d5293541c86729ed506 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.0E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS03570 6e4824b71a1c7d5293541c86729ed506 146 SUPERFAMILY SSF46785 6 139 2.55E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS25040 40b9a37b0a391e59f0fd81a1bfd31053 669 Gene3D G3DSA:2.60.60.30 68 160 7.3E-16 T 06-07-2017 SMD11_RS25040 40b9a37b0a391e59f0fd81a1bfd31053 669 Pfam PF02342 TerD domain 66 161 1.5E-16 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS33550 7177aa6ac7dbbcd3fd76d57838c0bb5e 324 SUPERFAMILY SSF51735 19 196 7.23E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33550 7177aa6ac7dbbcd3fd76d57838c0bb5e 324 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 196 221 - T 06-07-2017 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS33550 7177aa6ac7dbbcd3fd76d57838c0bb5e 324 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 21 190 2.5E-46 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS33550 7177aa6ac7dbbcd3fd76d57838c0bb5e 324 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 199 264 9.7E-12 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 SMD11_RS33550 7177aa6ac7dbbcd3fd76d57838c0bb5e 324 PIRSF PIRSF000105 13 320 2.4E-67 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 SMD11_RS33550 7177aa6ac7dbbcd3fd76d57838c0bb5e 324 SUPERFAMILY SSF48179 199 284 2.64E-11 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SMD11_RS33550 7177aa6ac7dbbcd3fd76d57838c0bb5e 324 Gene3D G3DSA:3.40.50.720 19 200 1.4E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33550 7177aa6ac7dbbcd3fd76d57838c0bb5e 324 Gene3D G3DSA:1.10.1040.10 201 252 2.5E-7 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SMD11_RS03050 abb06b1aa909ff870eb3668ca46f70a6 229 Gene3D G3DSA:3.10.450.50 94 218 3.1E-29 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS03050 abb06b1aa909ff870eb3668ca46f70a6 229 Pfam PF12680 SnoaL-like domain 95 204 3.1E-14 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain SMD11_RS03050 abb06b1aa909ff870eb3668ca46f70a6 229 SUPERFAMILY SSF54427 94 218 3.88E-30 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS07235 abaf76989b52682df3987192698a021e 265 SUPERFAMILY SSF53800 2 236 4.14E-44 T 06-07-2017 SMD11_RS07235 abaf76989b52682df3987192698a021e 265 Pfam PF01903 CbiX 8 112 8.5E-20 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 SMD11_RS07235 abaf76989b52682df3987192698a021e 265 Pfam PF01903 CbiX 136 211 5.5E-13 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 SMD11_RS07235 abaf76989b52682df3987192698a021e 265 Gene3D G3DSA:3.40.50.1400 128 239 1.7E-19 T 06-07-2017 SMD11_RS07235 abaf76989b52682df3987192698a021e 265 Gene3D G3DSA:3.40.50.1400 2 119 5.9E-25 T 06-07-2017 SMD11_RS32705 1dc211d70116980793429db8d2a8dabc 169 Gene3D G3DSA:3.40.630.30 1 162 4.3E-34 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS32705 1dc211d70116980793429db8d2a8dabc 169 Pfam PF00583 Acetyltransferase (GNAT) family 63 139 1.9E-15 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS32705 1dc211d70116980793429db8d2a8dabc 169 SUPERFAMILY SSF55729 1 161 2.87E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS04465 cf1c168bbe5199e94c3c4ef17021e82b 86 Gene3D G3DSA:1.10.1200.10 6 80 1.1E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS04465 cf1c168bbe5199e94c3c4ef17021e82b 86 Pfam PF00550 Phosphopantetheine attachment site 22 78 3.4E-6 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS04465 cf1c168bbe5199e94c3c4ef17021e82b 86 SUPERFAMILY SSF47336 8 80 2.09E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS05810 372656abecd1b36f490edf063c8ae7d1 592 Gene3D G3DSA:3.50.50.60 478 549 7.3E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05810 372656abecd1b36f490edf063c8ae7d1 592 Gene3D G3DSA:3.50.50.60 272 349 7.3E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05810 372656abecd1b36f490edf063c8ae7d1 592 Gene3D G3DSA:3.50.50.60 45 127 7.3E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05810 372656abecd1b36f490edf063c8ae7d1 592 Gene3D G3DSA:3.50.50.60 208 209 7.3E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05810 372656abecd1b36f490edf063c8ae7d1 592 Pfam PF01593 Flavin containing amine oxidoreductase 53 549 2.1E-17 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD11_RS05810 372656abecd1b36f490edf063c8ae7d1 592 SUPERFAMILY SSF51905 43 383 4.21E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05810 372656abecd1b36f490edf063c8ae7d1 592 SUPERFAMILY SSF51905 508 551 4.21E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01185 90f5a414e6804ea6dcd8b17156f5e991 260 SMART SM00563 35 154 7.0E-35 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD11_RS01185 90f5a414e6804ea6dcd8b17156f5e991 260 Gene3D G3DSA:3.40.1130.10 3 208 8.1E-33 T 06-07-2017 SMD11_RS01185 90f5a414e6804ea6dcd8b17156f5e991 260 Pfam PF01553 Acyltransferase 21 151 1.7E-22 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SMD11_RS01185 90f5a414e6804ea6dcd8b17156f5e991 260 SUPERFAMILY SSF69593 2 222 2.75E-51 T 06-07-2017 SMD11_RS11570 199e3aec16d8b2025aaf6543cac202d7 120 Pfam PF02467 Transcription factor WhiB 47 95 1.2E-16 T 06-07-2017 IPR003482 Transcription factor WhiB SMD11_RS11570 199e3aec16d8b2025aaf6543cac202d7 120 ProSitePatterns PS00354 HMG-I and HMG-Y DNA-binding domain (A+T-hook). 105 115 - T 06-07-2017 IPR000637 HMG-I/HMG-Y, DNA-binding, conserved site GO:0006355 SMD11_RS11570 199e3aec16d8b2025aaf6543cac202d7 120 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 25 109 15.499 T 06-07-2017 IPR003482 Transcription factor WhiB SMD11_RS14325 17633843ac981f614c0881481b843003 473 Pfam PF00668 Condensation domain 59 335 2.2E-32 T 06-07-2017 IPR001242 Condensation domain SMD11_RS14325 17633843ac981f614c0881481b843003 473 SUPERFAMILY SSF52777 225 411 3.11E-20 T 06-07-2017 SMD11_RS14325 17633843ac981f614c0881481b843003 473 SUPERFAMILY SSF52777 55 215 2.78E-27 T 06-07-2017 SMD11_RS14025 2bf9fd707be8afaa1f3e0db006fd9d15 314 SUPERFAMILY SSF55797 188 311 2.35E-25 T 06-07-2017 IPR014044 CAP domain SMD11_RS14025 2bf9fd707be8afaa1f3e0db006fd9d15 314 Gene3D G3DSA:3.40.33.10 187 309 2.1E-14 T 06-07-2017 IPR014044 CAP domain SMD11_RS14025 2bf9fd707be8afaa1f3e0db006fd9d15 314 Pfam PF00188 Cysteine-rich secretory protein family 195 310 9.6E-22 T 06-07-2017 IPR014044 CAP domain SMD11_RS30650 42073c380da690f130f2509a928cb182 294 ProSitePatterns PS00761 Signal peptidases I signature 3. 198 211 - T 06-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 SMD11_RS30650 42073c380da690f130f2509a928cb182 294 Pfam PF00717 Peptidase S24-like 70 167 3.9E-14 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B SMD11_RS30650 42073c380da690f130f2509a928cb182 294 SUPERFAMILY SSF51306 62 110 9.31E-48 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C SMD11_RS30650 42073c380da690f130f2509a928cb182 294 SUPERFAMILY SSF51306 137 245 9.31E-48 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C SMD11_RS30650 42073c380da690f130f2509a928cb182 294 Gene3D G3DSA:2.10.109.10 193 245 7.7E-40 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain SMD11_RS30650 42073c380da690f130f2509a928cb182 294 Gene3D G3DSA:2.10.109.10 59 152 7.7E-40 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain SMD11_RS30650 42073c380da690f130f2509a928cb182 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 142 154 3.1E-19 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS30650 42073c380da690f130f2509a928cb182 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 193 212 3.1E-19 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS30650 42073c380da690f130f2509a928cb182 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 63 79 3.1E-19 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS30650 42073c380da690f130f2509a928cb182 294 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 49 240 2.1E-42 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS02305 235c9a159c5882d24224d44eccfd2532 523 SUPERFAMILY SSF51905 262 483 5.96E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02305 235c9a159c5882d24224d44eccfd2532 523 SUPERFAMILY SSF51905 19 255 5.18E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02305 235c9a159c5882d24224d44eccfd2532 523 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 187 205 6.7E-5 T 06-07-2017 SMD11_RS02305 235c9a159c5882d24224d44eccfd2532 523 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 23 42 6.7E-5 T 06-07-2017 SMD11_RS02305 235c9a159c5882d24224d44eccfd2532 523 Gene3D G3DSA:3.50.50.60 14 222 1.4E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02305 235c9a159c5882d24224d44eccfd2532 523 Gene3D G3DSA:3.50.50.60 318 496 1.0E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS02305 235c9a159c5882d24224d44eccfd2532 523 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 24 221 8.8E-16 T 06-07-2017 SMD11_RS02305 235c9a159c5882d24224d44eccfd2532 523 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 187 212 4.4E-8 T 06-07-2017 SMD11_RS02305 235c9a159c5882d24224d44eccfd2532 523 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 22 44 4.4E-8 T 06-07-2017 SMD11_RS02305 235c9a159c5882d24224d44eccfd2532 523 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 155 4.4E-8 T 06-07-2017 SMD11_RS14490 953972ecbe8fae44b1b385381f5dbe3d 198 SUPERFAMILY SSF46689 6 86 1.69E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS14490 953972ecbe8fae44b1b385381f5dbe3d 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 2.1E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS14490 953972ecbe8fae44b1b385381f5dbe3d 198 Gene3D G3DSA:1.10.357.10 16 186 1.4E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS00255 cfa36ec6c07c3e1c768076197fb739f4 196 Pfam PF00583 Acetyltransferase (GNAT) family 116 174 1.6E-6 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS00255 cfa36ec6c07c3e1c768076197fb739f4 196 SUPERFAMILY SSF55729 9 191 3.9E-15 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS00255 cfa36ec6c07c3e1c768076197fb739f4 196 Gene3D G3DSA:3.40.630.30 10 194 1.7E-35 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS20990 cdca044a2f7fbd6b21655a1b324d3465 248 Pfam PF13490 Putative zinc-finger 11 37 3.7E-6 T 06-07-2017 IPR027383 Putative zinc-finger SMD11_RS12145 da926972976eb34783af30b924f35845 196 Gene3D G3DSA:3.40.109.10 13 194 5.1E-40 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS12145 da926972976eb34783af30b924f35845 196 SUPERFAMILY SSF55469 14 194 5.89E-40 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS12145 da926972976eb34783af30b924f35845 196 Pfam PF00881 Nitroreductase family 15 174 8.5E-19 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 Gene3D G3DSA:3.30.450.40 269 444 5.0E-39 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 140 258 1.5E-5 T 06-07-2017 IPR000014 PAS domain SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 Gene3D G3DSA:3.30.450.20 9 125 2.7E-8 T 06-07-2017 SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 Gene3D G3DSA:3.30.450.20 139 252 4.2E-17 T 06-07-2017 SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 Pfam PF13426 PAS domain 21 125 0.0094 T 06-07-2017 IPR000014 PAS domain SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 SUPERFAMILY SSF55781 264 453 5.1E-13 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 SUPERFAMILY SSF55785 139 250 8.9E-14 T 06-07-2017 IPR000014 PAS domain SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 SUPERFAMILY SSF55785 10 72 2.88E-6 T 06-07-2017 IPR000014 PAS domain SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 Pfam PF13185 GAF domain 281 437 1.5E-6 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 SUPERFAMILY SSF81606 481 699 2.88E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 SMART SM00331 467 698 1.3E-43 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 Pfam PF08448 PAS fold 143 254 9.8E-22 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 SUPERFAMILY SSF55874 739 822 2.63E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 SMART SM00091 136 202 0.28 T 06-07-2017 IPR000014 PAS domain SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 SMART SM00091 5 71 0.15 T 06-07-2017 IPR000014 PAS domain SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 493 698 1.5E-51 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 Pfam PF13581 Histidine kinase-like ATPase domain 712 819 2.3E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS12095 77ed5321a1aa4044a49e121df4a8f470 842 SMART SM00065 281 446 2.0E-5 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS06885 20652cd49cd452380aa5a06399dd16ff 213 Pfam PF07883 Cupin domain 121 187 3.0E-13 T 06-07-2017 IPR013096 Cupin 2, conserved barrel SMD11_RS06885 20652cd49cd452380aa5a06399dd16ff 213 SUPERFAMILY SSF51182 86 187 2.02E-21 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS06885 20652cd49cd452380aa5a06399dd16ff 213 Gene3D G3DSA:2.60.120.10 119 196 6.6E-18 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS06885 20652cd49cd452380aa5a06399dd16ff 213 Pfam PF13560 Helix-turn-helix domain 21 77 9.2E-18 T 06-07-2017 SMD11_RS06885 20652cd49cd452380aa5a06399dd16ff 213 SUPERFAMILY SSF47413 18 82 3.49E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS06885 20652cd49cd452380aa5a06399dd16ff 213 SMART SM00530 23 78 7.7E-17 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS06885 20652cd49cd452380aa5a06399dd16ff 213 Gene3D G3DSA:1.10.260.40 20 118 9.7E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS02120 892679150551e754de1db82084e9566d 388 SUPERFAMILY SSF81606 174 381 8.37E-5 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS02120 892679150551e754de1db82084e9566d 388 SMART SM00331 160 381 1.4E-25 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS02120 892679150551e754de1db82084e9566d 388 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 188 381 3.8E-36 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS21975 512abb6a55ab5e9c6ef60b7495d43e4f 634 SUPERFAMILY SSF53756 184 427 3.56E-7 T 06-07-2017 SMD11_RS28225 e92977216591fba69c8b5caf68c5dbe2 271 Pfam PF02567 Phenazine biosynthesis-like protein 6 267 1.2E-61 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMD11_RS28225 e92977216591fba69c8b5caf68c5dbe2 271 Gene3D G3DSA:3.10.310.10 2 126 1.3E-40 T 06-07-2017 SMD11_RS28225 e92977216591fba69c8b5caf68c5dbe2 271 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 267 9.6E-38 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMD11_RS28225 e92977216591fba69c8b5caf68c5dbe2 271 SUPERFAMILY SSF54506 2 270 9.74E-73 T 06-07-2017 SMD11_RS28225 e92977216591fba69c8b5caf68c5dbe2 271 PIRSF PIRSF016184 1 271 5.5E-48 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SMD11_RS28225 e92977216591fba69c8b5caf68c5dbe2 271 Gene3D G3DSA:3.10.310.10 127 259 4.5E-38 T 06-07-2017 SMD11_RS33020 7e11c11783b8218de8bf042720919807 375 Gene3D G3DSA:1.10.540.10 1 122 2.4E-4 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 SMD11_RS33020 7e11c11783b8218de8bf042720919807 375 SUPERFAMILY SSF56645 1 197 1.21E-14 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SMD11_RS33020 7e11c11783b8218de8bf042720919807 375 Gene3D G3DSA:1.20.140.10 232 365 1.6E-22 T 06-07-2017 SMD11_RS33020 7e11c11783b8218de8bf042720919807 375 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 351 1.8E-17 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS33020 7e11c11783b8218de8bf042720919807 375 SUPERFAMILY SSF47203 231 366 1.61E-22 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS12255 d85395daab68e8bbb2ebb6c65036532c 253 Gene3D G3DSA:3.40.1180.10 10 253 2.7E-86 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD11_RS12255 d85395daab68e8bbb2ebb6c65036532c 253 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 24 253 35.851 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD11_RS12255 d85395daab68e8bbb2ebb6c65036532c 253 Pfam PF01255 Putative undecaprenyl diphosphate synthase 31 252 1.1E-69 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD11_RS12255 d85395daab68e8bbb2ebb6c65036532c 253 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 198 215 - T 06-07-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 SMD11_RS12255 d85395daab68e8bbb2ebb6c65036532c 253 SUPERFAMILY SSF64005 19 247 2.22E-73 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD11_RS12255 d85395daab68e8bbb2ebb6c65036532c 253 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 24 252 4.1E-64 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SMD11_RS12975 737b87856da09ad724165ffe45d7850e 456 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 5 342 1.3E-79 T 06-07-2017 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase SMD11_RS12975 737b87856da09ad724165ffe45d7850e 456 Gene3D G3DSA:3.50.50.60 93 199 4.7E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12975 737b87856da09ad724165ffe45d7850e 456 SUPERFAMILY SSF51905 268 357 8.2E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12975 737b87856da09ad724165ffe45d7850e 456 Gene3D G3DSA:3.50.50.60 280 339 4.2E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12975 737b87856da09ad724165ffe45d7850e 456 Gene3D G3DSA:3.50.50.60 200 231 4.2E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS12975 737b87856da09ad724165ffe45d7850e 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 2.8E-6 T 06-07-2017 SMD11_RS12975 737b87856da09ad724165ffe45d7850e 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 193 211 2.8E-6 T 06-07-2017 SMD11_RS12975 737b87856da09ad724165ffe45d7850e 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 2.8E-6 T 06-07-2017 SMD11_RS12975 737b87856da09ad724165ffe45d7850e 456 SUPERFAMILY SSF51905 5 250 7.24E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24640 355cfa53f38cd73db5d72470807f0c4b 439 Pfam PF01936 NYN domain 38 166 5.3E-11 T 06-07-2017 IPR021139 NYN domain, limkain-b1-type SMD11_RS24640 355cfa53f38cd73db5d72470807f0c4b 439 Gene3D G3DSA:3.40.50.1010 3 172 6.3E-16 T 06-07-2017 IPR029060 PIN domain-like SMD11_RS17290 11e023ecf9e3ab37762e90e2cb3335f5 216 Pfam PF14016 Protein of unknown function (DUF4232) 79 207 6.4E-23 T 06-07-2017 IPR025326 Protein of unknown function DUF4232 SMD11_RS21540 c1b991257c1bbabd7bbfc28394b9423c 325 SUPERFAMILY SSF54001 201 322 4.51E-35 T 06-07-2017 SMD11_RS21540 c1b991257c1bbabd7bbfc28394b9423c 325 Pfam PF00877 NlpC/P60 family 220 319 1.6E-23 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS21540 c1b991257c1bbabd7bbfc28394b9423c 325 Gene3D G3DSA:3.90.1720.10 202 325 5.5E-38 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS02125 5e361db6dd9b325879513122b7fdf990 218 Gene3D G3DSA:2.30.110.10 1 205 2.9E-31 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS02125 5e361db6dd9b325879513122b7fdf990 218 Pfam PF04299 Putative FMN-binding domain 10 164 7.4E-20 T 06-07-2017 IPR007396 Transcriptional regulator PAI 2-type SMD11_RS02125 5e361db6dd9b325879513122b7fdf990 218 SUPERFAMILY SSF50475 13 188 2.14E-28 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS33280 efbbde0eba170997152540f6086a15ba 424 Pfam PF00202 Aminotransferase class-III 40 404 2.8E-74 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS33280 efbbde0eba170997152540f6086a15ba 424 SUPERFAMILY SSF53383 39 406 1.69E-94 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS33280 efbbde0eba170997152540f6086a15ba 424 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 229 266 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS33280 efbbde0eba170997152540f6086a15ba 424 Gene3D G3DSA:3.90.1150.10 300 411 5.2E-32 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS33280 efbbde0eba170997152540f6086a15ba 424 Gene3D G3DSA:3.40.640.10 69 299 4.2E-69 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS03970 2bdf9e0e5a9798008b4b5895a975fb0e 71 Pfam PF07311 Dodecin 5 68 3.3E-27 T 06-07-2017 IPR009923 Dodecin SMD11_RS03970 2bdf9e0e5a9798008b4b5895a975fb0e 71 Gene3D G3DSA:3.30.1660.10 2 69 3.4E-34 T 06-07-2017 IPR025543 Dodecin-like SMD11_RS03970 2bdf9e0e5a9798008b4b5895a975fb0e 71 SUPERFAMILY SSF89807 3 68 1.57E-23 T 06-07-2017 IPR009923 Dodecin SMD11_RS33260 ecf281017612b34f21c607f961b7f97b 260 Pfam PF01061 ABC-2 type transporter 9 219 1.8E-26 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD11_RS33260 ecf281017612b34f21c607f961b7f97b 260 PIRSF PIRSF006648 6 256 6.0E-17 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS22600 bebaf22d699d9706b38ab972a3088d0c 629 Gene3D G3DSA:3.40.50.980 360 422 7.9E-25 T 06-07-2017 SMD11_RS22600 bebaf22d699d9706b38ab972a3088d0c 629 Gene3D G3DSA:3.40.50.980 210 301 7.9E-25 T 06-07-2017 SMD11_RS22600 bebaf22d699d9706b38ab972a3088d0c 629 ProSitePatterns PS00455 Putative AMP-binding domain signature. 204 215 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS22600 bebaf22d699d9706b38ab972a3088d0c 629 SUPERFAMILY SSF56801 363 624 9.29E-116 T 06-07-2017 SMD11_RS22600 bebaf22d699d9706b38ab972a3088d0c 629 SUPERFAMILY SSF56801 9 306 9.29E-116 T 06-07-2017 SMD11_RS22600 bebaf22d699d9706b38ab972a3088d0c 629 Gene3D G3DSA:3.40.50.980 14 157 4.4E-34 T 06-07-2017 SMD11_RS22600 bebaf22d699d9706b38ab972a3088d0c 629 Gene3D G3DSA:3.40.50.980 189 209 4.4E-34 T 06-07-2017 SMD11_RS22600 bebaf22d699d9706b38ab972a3088d0c 629 Gene3D G3DSA:2.30.38.10 423 484 1.1E-20 T 06-07-2017 SMD11_RS22600 bebaf22d699d9706b38ab972a3088d0c 629 Pfam PF00501 AMP-binding enzyme 21 493 1.4E-93 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS18835 3fcb20120b9bceb908860f63f6f30a73 128 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 128 21.562 T 06-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18835 3fcb20120b9bceb908860f63f6f30a73 128 SUPERFAMILY SSF48300 5 64 1.44E-12 T 06-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18835 3fcb20120b9bceb908860f63f6f30a73 128 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 62 128 2.6E-27 T 06-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18835 3fcb20120b9bceb908860f63f6f30a73 128 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 128 5.6E-44 T 06-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18835 3fcb20120b9bceb908860f63f6f30a73 128 Gene3D G3DSA:3.30.1390.10 56 128 1.2E-30 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMD11_RS18835 3fcb20120b9bceb908860f63f6f30a73 128 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 55 3.5E-14 T 06-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18835 3fcb20120b9bceb908860f63f6f30a73 128 Gene3D G3DSA:1.20.5.710 3 54 1.6E-14 T 06-07-2017 SMD11_RS18835 3fcb20120b9bceb908860f63f6f30a73 128 SUPERFAMILY SSF54736 57 128 4.53E-22 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMD11_RS18835 3fcb20120b9bceb908860f63f6f30a73 128 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 63 101 2.0E-14 T 06-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 Gene3D G3DSA:1.10.630.10 14 415 4.1E-113 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 SUPERFAMILY SSF48264 15 415 4.58E-89 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 PRINTS PR00385 P450 superfamily signature 362 373 1.5E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 PRINTS PR00385 P450 superfamily signature 353 362 1.5E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 PRINTS PR00385 P450 superfamily signature 284 295 1.5E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 PRINTS PR00385 P450 superfamily signature 249 266 1.5E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 355 364 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 PRINTS PR00359 B-class P450 signature 302 329 7.6E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 PRINTS PR00359 B-class P450 signature 165 180 7.6E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 PRINTS PR00359 B-class P450 signature 284 295 7.6E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 PRINTS PR00359 B-class P450 signature 353 362 7.6E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 PRINTS PR00359 B-class P450 signature 202 224 7.6E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 PRINTS PR00359 B-class P450 signature 362 373 7.6E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 PRINTS PR00359 B-class P450 signature 93 104 7.6E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 Pfam PF00067 Cytochrome P450 285 383 1.0E-15 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS03435 e2047a0c5140aee1593fb7e2a70d7c54 432 Pfam PF00067 Cytochrome P450 216 271 3.1E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS18445 0c7d8c286bf5e29867f119d790c73592 95 Pfam PF14012 Protein of unknown function (DUF4229) 9 80 1.0E-22 T 06-07-2017 IPR025323 Protein of unknown function DUF4229 SMD11_RS06360 4590bbd22dcc947b2691c7916823069c 76 Gene3D G3DSA:1.10.1200.10 3 72 5.1E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS06360 4590bbd22dcc947b2691c7916823069c 76 SUPERFAMILY SSF47336 3 75 6.94E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS06360 4590bbd22dcc947b2691c7916823069c 76 Pfam PF00550 Phosphopantetheine attachment site 6 69 2.0E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS06360 4590bbd22dcc947b2691c7916823069c 76 SMART SM00823 Phosphopantetheine attachment site 5 63 0.008 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS12630 240897c46597f718f8561f086c17eca3 252 Pfam PF01614 Bacterial transcriptional regulator 122 236 3.3E-24 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal SMD11_RS12630 240897c46597f718f8561f086c17eca3 252 SUPERFAMILY SSF46785 3 74 9.11E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12630 240897c46597f718f8561f086c17eca3 252 Pfam PF09339 IclR helix-turn-helix domain 4 53 2.8E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS12630 240897c46597f718f8561f086c17eca3 252 Gene3D G3DSA:1.10.10.10 3 63 4.7E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS12630 240897c46597f718f8561f086c17eca3 252 SMART SM00346 2 90 3.7E-4 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS12630 240897c46597f718f8561f086c17eca3 252 Gene3D G3DSA:3.30.450.40 73 240 1.7E-32 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS12630 240897c46597f718f8561f086c17eca3 252 SUPERFAMILY SSF55781 71 239 6.54E-30 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS01465 f2e09150fb653c16bb863ac74d355369 217 SUPERFAMILY SSF48498 82 186 8.26E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS01465 f2e09150fb653c16bb863ac74d355369 217 Pfam PF13305 WHG domain 84 181 6.4E-15 T 06-07-2017 IPR025996 WHG domain SMD11_RS01465 f2e09150fb653c16bb863ac74d355369 217 Gene3D G3DSA:1.10.357.10 7 209 3.4E-38 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS01465 f2e09150fb653c16bb863ac74d355369 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 1.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS01465 f2e09150fb653c16bb863ac74d355369 217 SUPERFAMILY SSF46689 6 72 2.1E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS08385 6ea66d108ca1f424773c6011eacb2a52 193 Pfam PF03358 NADPH-dependent FMN reductase 2 150 8.9E-34 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMD11_RS08385 6ea66d108ca1f424773c6011eacb2a52 193 SUPERFAMILY SSF52218 3 175 3.83E-39 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS08385 6ea66d108ca1f424773c6011eacb2a52 193 Gene3D G3DSA:3.40.50.360 1 188 2.8E-46 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS04320 fb9c187c15fd39a1bd6e31805f25f341 250 Gene3D G3DSA:3.40.50.2300 186 235 8.9E-4 T 06-07-2017 SMD11_RS04320 fb9c187c15fd39a1bd6e31805f25f341 250 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 6 245 1.0E-73 T 06-07-2017 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 SMD11_RS04320 fb9c187c15fd39a1bd6e31805f25f341 250 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 6 248 1.2E-46 T 06-07-2017 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 SMD11_RS03460 060cc47413dfc9af8962530dc4c30e1f 171 Gene3D G3DSA:3.40.630.30 10 133 5.7E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS03460 060cc47413dfc9af8962530dc4c30e1f 171 Pfam PF00583 Acetyltransferase (GNAT) family 58 129 7.0E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS03460 060cc47413dfc9af8962530dc4c30e1f 171 SUPERFAMILY SSF55729 10 136 6.58E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS00030 22c974f6037ee2db1acbd3eb39f26d75 530 SUPERFAMILY SSF103473 250 424 5.36E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS00030 22c974f6037ee2db1acbd3eb39f26d75 530 SUPERFAMILY SSF103473 479 503 5.36E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS00030 22c974f6037ee2db1acbd3eb39f26d75 530 SUPERFAMILY SSF103473 7 202 5.36E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS00030 22c974f6037ee2db1acbd3eb39f26d75 530 Gene3D G3DSA:1.20.1250.20 265 425 2.4E-15 T 06-07-2017 SMD11_RS00030 22c974f6037ee2db1acbd3eb39f26d75 530 Gene3D G3DSA:1.20.1250.20 481 504 2.4E-15 T 06-07-2017 SMD11_RS00030 22c974f6037ee2db1acbd3eb39f26d75 530 Gene3D G3DSA:1.20.1250.20 19 188 7.8E-23 T 06-07-2017 SMD11_RS00030 22c974f6037ee2db1acbd3eb39f26d75 530 Pfam PF07690 Major Facilitator Superfamily 21 406 4.2E-39 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS16685 af86e21521207b90daacdde1f3c0f15e 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 114 6.8E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS16685 af86e21521207b90daacdde1f3c0f15e 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 94 6.8E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS16685 af86e21521207b90daacdde1f3c0f15e 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 78 6.8E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS16685 af86e21521207b90daacdde1f3c0f15e 153 Gene3D G3DSA:1.10.10.10 14 144 2.9E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16685 af86e21521207b90daacdde1f3c0f15e 153 Pfam PF12802 MarR family 38 102 1.8E-10 T 06-07-2017 SMD11_RS16685 af86e21521207b90daacdde1f3c0f15e 153 SMART SM00347 33 138 9.9E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS16685 af86e21521207b90daacdde1f3c0f15e 153 SUPERFAMILY SSF46785 15 139 1.61E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04250 4f9126e9fcfcb9c8814d42a5db2db11e 161 SUPERFAMILY SSF47413 55 94 5.32E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS04250 4f9126e9fcfcb9c8814d42a5db2db11e 161 Pfam PF01381 Helix-turn-helix 55 90 4.7E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS04250 4f9126e9fcfcb9c8814d42a5db2db11e 161 Gene3D G3DSA:1.10.260.40 54 139 4.6E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS01035 a5c0450d78965483628eefebebc2660f 259 Pfam PF08241 Methyltransferase domain 45 134 8.7E-17 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS01035 a5c0450d78965483628eefebebc2660f 259 SUPERFAMILY SSF53335 9 150 1.7E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS01035 a5c0450d78965483628eefebebc2660f 259 Gene3D G3DSA:3.40.50.150 24 168 8.1E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS01035 a5c0450d78965483628eefebebc2660f 259 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 44 71 - T 06-07-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 SMD11_RS15290 9e24e72cf699645a6626e1dda576da33 797 PIRSF PIRSF001265 20 746 2.2E-263 T 06-07-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 SMD11_RS15290 9e24e72cf699645a6626e1dda576da33 797 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 29 740 6.6E-203 T 06-07-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 SMD11_RS15290 9e24e72cf699645a6626e1dda576da33 797 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 25 739 24.443 T 06-07-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 SMD11_RS15290 9e24e72cf699645a6626e1dda576da33 797 Pfam PF03030 Inorganic H+ pyrophosphatase 37 734 5.0E-239 T 06-07-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 SMD11_RS05270 0cca3ab35416472fec853dc4352a74b2 282 Gene3D G3DSA:3.40.50.150 8 281 4.0E-101 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS05270 0cca3ab35416472fec853dc4352a74b2 282 SUPERFAMILY SSF53335 20 265 1.73E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS05270 0cca3ab35416472fec853dc4352a74b2 282 Pfam PF04672 S-adenosyl methyltransferase 12 281 1.1E-94 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD11_RS05270 0cca3ab35416472fec853dc4352a74b2 282 PIRSF PIRSF017393 1 282 9.3E-97 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD11_RS15795 bef315fb0f92ef3a00015b38d4eea474 524 SUPERFAMILY SSF52540 43 410 1.16E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15795 bef315fb0f92ef3a00015b38d4eea474 524 Pfam PF05872 Bacterial protein of unknown function (DUF853) 48 523 1.1E-180 T 06-07-2017 IPR033186 Helicase HerA-like C-terminal SMD11_RS15795 bef315fb0f92ef3a00015b38d4eea474 524 Gene3D G3DSA:3.40.50.300 241 405 1.3E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15795 bef315fb0f92ef3a00015b38d4eea474 524 Gene3D G3DSA:3.40.50.300 40 124 1.3E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30520 7131dde1cede6098287e863d0a0d13ae 313 SUPERFAMILY SSF53474 30 283 1.01E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30520 7131dde1cede6098287e863d0a0d13ae 313 Pfam PF12697 Alpha/beta hydrolase family 39 307 2.0E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS30520 7131dde1cede6098287e863d0a0d13ae 313 Gene3D G3DSA:3.40.50.1820 35 300 3.2E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS06125 fcaf396c2ccdac41f0e0476025cdbc64 278 SUPERFAMILY SSF54001 47 138 2.32E-7 T 06-07-2017 SMD11_RS06125 fcaf396c2ccdac41f0e0476025cdbc64 278 Pfam PF05257 CHAP domain 43 121 3.3E-10 T 06-07-2017 IPR007921 CHAP domain SMD11_RS30835 639ba69c32ff31f2336c44dbddcfdaf0 319 SUPERFAMILY SSF103481 62 155 4.71E-5 T 06-07-2017 SMD11_RS30835 639ba69c32ff31f2336c44dbddcfdaf0 319 Pfam PF00892 EamA-like transporter family 163 292 5.5E-12 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS30835 639ba69c32ff31f2336c44dbddcfdaf0 319 SUPERFAMILY SSF103481 202 300 1.83E-8 T 06-07-2017 SMD11_RS31990 61a46ca465e713b3fef690ff038b095d 506 Pfam PF00135 Carboxylesterase family 7 459 2.2E-83 T 06-07-2017 IPR002018 Carboxylesterase, type B SMD11_RS31990 61a46ca465e713b3fef690ff038b095d 506 Gene3D G3DSA:3.40.50.1820 4 493 2.4E-118 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS31990 61a46ca465e713b3fef690ff038b095d 506 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 172 187 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site SMD11_RS31990 61a46ca465e713b3fef690ff038b095d 506 SUPERFAMILY SSF53474 6 494 2.56E-105 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS31565 715505849ddd7fa263f642182906c12d 431 SUPERFAMILY SSF103473 15 410 3.01E-28 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS31565 715505849ddd7fa263f642182906c12d 431 Gene3D G3DSA:1.20.1250.20 15 206 2.7E-12 T 06-07-2017 SMD11_RS31565 715505849ddd7fa263f642182906c12d 431 Gene3D G3DSA:1.20.1250.20 234 412 3.7E-10 T 06-07-2017 SMD11_RS31565 715505849ddd7fa263f642182906c12d 431 Pfam PF05977 Transmembrane secretion effector 14 409 2.3E-13 T 06-07-2017 IPR010290 Transmembrane secretion effector SMD11_RS04905 94d4460c720311c2c975476ed9453aff 337 SUPERFAMILY SSF55120 211 334 2.73E-46 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS04905 94d4460c720311c2c975476ed9453aff 337 SUPERFAMILY SSF55120 5 181 2.73E-46 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS04905 94d4460c720311c2c975476ed9453aff 337 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 6 191 5.2E-33 T 06-07-2017 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 SMD11_RS33455 0fc92b1d9484de10d9ea727c8b664a84 58 Gene3D G3DSA:3.40.50.1820 1 55 1.5E-10 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS33455 0fc92b1d9484de10d9ea727c8b664a84 58 SUPERFAMILY SSF53474 1 55 4.32E-10 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS08835 723289c5481b6ad94ceae4b4481bcb10 538 SUPERFAMILY SSF53383 28 379 1.38E-101 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS08835 723289c5481b6ad94ceae4b4481bcb10 538 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 19 379 2.0E-128 T 06-07-2017 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 SMD11_RS08835 723289c5481b6ad94ceae4b4481bcb10 538 Gene3D G3DSA:3.40.640.10 75 316 5.0E-64 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS08835 723289c5481b6ad94ceae4b4481bcb10 538 Gene3D G3DSA:3.90.1150.10 317 382 1.5E-53 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS08835 723289c5481b6ad94ceae4b4481bcb10 538 Gene3D G3DSA:3.90.1150.10 460 516 1.5E-53 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS08835 723289c5481b6ad94ceae4b4481bcb10 538 Pfam PF00202 Aminotransferase class-III 37 379 7.9E-80 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS08835 723289c5481b6ad94ceae4b4481bcb10 538 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 252 289 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS08835 723289c5481b6ad94ceae4b4481bcb10 538 SUPERFAMILY SSF53383 460 513 1.34E-7 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS11795 2e1c751c95ff5970ac80d35e9a7f58af 180 Pfam PF06210 Protein of unknown function (DUF1003) 51 152 1.9E-41 T 06-07-2017 IPR010406 Protein of unknown function DUF1003 SMD11_RS17320 f3f78b46199084daf4e9e92db49df608 317 Pfam PF05726 Pirin C-terminal cupin domain 201 309 1.4E-30 T 06-07-2017 IPR008778 Pirin, C-terminal domain SMD11_RS17320 f3f78b46199084daf4e9e92db49df608 317 Pfam PF02678 Pirin 41 146 5.2E-31 T 06-07-2017 IPR003829 Pirin, N-terminal domain SMD11_RS17320 f3f78b46199084daf4e9e92db49df608 317 Gene3D G3DSA:2.60.120.10 24 282 1.0E-74 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS17320 f3f78b46199084daf4e9e92db49df608 317 PIRSF PIRSF006232 22 317 8.5E-89 T 06-07-2017 IPR012093 Pirin SMD11_RS17320 f3f78b46199084daf4e9e92db49df608 317 SUPERFAMILY SSF51182 26 314 5.21E-81 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS12805 14d4d941cf0983f6e3301c429eaf7569 177 Pfam PF13302 Acetyltransferase (GNAT) domain 8 150 4.3E-31 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS12805 14d4d941cf0983f6e3301c429eaf7569 177 SUPERFAMILY SSF55729 1 153 3.21E-37 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS12805 14d4d941cf0983f6e3301c429eaf7569 177 Gene3D G3DSA:3.40.630.30 2 155 1.2E-45 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS20195 209855bad3c5272a4987f681e9dbdafe 176 Pfam PF14431 YwqJ-like deaminase 39 163 2.3E-26 T 06-07-2017 IPR025968 YwqJ-like deaminase SMD11_RS20500 e156875797dc26e0a1b610bf8254decc 552 Hamap MF_00577 Urocanate hydratase [hutU]. 2 550 48.783 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD11_RS20500 e156875797dc26e0a1b610bf8254decc 552 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 548 5.4E-274 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD11_RS20500 e156875797dc26e0a1b610bf8254decc 552 Gene3D G3DSA:3.40.50.10730 137 343 8.1E-84 T 06-07-2017 SMD11_RS20500 e156875797dc26e0a1b610bf8254decc 552 Gene3D G3DSA:3.40.1770.10 354 548 5.2E-151 T 06-07-2017 SMD11_RS20500 e156875797dc26e0a1b610bf8254decc 552 Gene3D G3DSA:3.40.1770.10 6 136 5.2E-151 T 06-07-2017 SMD11_RS20500 e156875797dc26e0a1b610bf8254decc 552 SUPERFAMILY SSF111326 4 549 1.01E-246 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD11_RS20500 e156875797dc26e0a1b610bf8254decc 552 ProSitePatterns PS01233 Urocanase signature. 436 451 - T 06-07-2017 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD11_RS20500 e156875797dc26e0a1b610bf8254decc 552 Pfam PF01175 Urocanase 7 541 1.6E-251 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD11_RS20500 e156875797dc26e0a1b610bf8254decc 552 PIRSF PIRSF001423 1 552 1.4E-277 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SMD11_RS06310 8a55136b696864a8526eea8820ac49de 681 Pfam PF17128 Domain of unknown function (DUF5107) 59 340 2.2E-34 T 06-07-2017 IPR033396 Domain of unknown function DUF5107 SMD11_RS07120 f76422ad75d2c27e5532d8b5bd15a9c5 260 SUPERFAMILY SSF48452 73 227 1.4E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS07120 f76422ad75d2c27e5532d8b5bd15a9c5 260 Gene3D G3DSA:1.25.40.10 73 232 1.2E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS15060 e2a6727ce39b1550ad03a1cbd84b95a0 101 Gene3D G3DSA:4.10.830.10 41 101 9.3E-27 T 06-07-2017 SMD11_RS15060 e2a6727ce39b1550ad03a1cbd84b95a0 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 5.1E-23 T 06-07-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS15060 e2a6727ce39b1550ad03a1cbd84b95a0 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.14 T 06-07-2017 IPR023036 Ribosomal protein S14, bacterial/plastid SMD11_RS15060 e2a6727ce39b1550ad03a1cbd84b95a0 101 SUPERFAMILY SSF57716 2 101 5.23E-34 T 06-07-2017 SMD11_RS03475 0ddd5963795dd9a179019b446160eaae 364 Gene3D G3DSA:3.20.20.70 2 359 4.0E-135 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS03475 0ddd5963795dd9a179019b446160eaae 364 SUPERFAMILY SSF51395 2 357 2.48E-116 T 06-07-2017 SMD11_RS03475 0ddd5963795dd9a179019b446160eaae 364 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 348 7.2E-74 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMD11_RS17375 31d0e1cf9caf576f5f756aea05a9653d 466 Pfam PF03055 Retinal pigment epithelial membrane protein 20 463 5.5E-90 T 06-07-2017 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 SMD11_RS09245 35ad3ddc093bc36670a748b20eed654e 92 Gene3D G3DSA:3.30.1230.10 7 89 3.2E-24 T 06-07-2017 IPR007393 Domain of unknown function DUF448 SMD11_RS09245 35ad3ddc093bc36670a748b20eed654e 92 Pfam PF04296 Protein of unknown function (DUF448) 13 88 1.1E-21 T 06-07-2017 IPR007393 Domain of unknown function DUF448 SMD11_RS09245 35ad3ddc093bc36670a748b20eed654e 92 SUPERFAMILY SSF64376 9 89 7.06E-22 T 06-07-2017 IPR007393 Domain of unknown function DUF448 SMD11_RS17850 af6572a4d844ceb1c0748c35a55e8931 403 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 206 360 5.1E-32 T 06-07-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 SMD11_RS17850 af6572a4d844ceb1c0748c35a55e8931 403 SUPERFAMILY SSF53756 10 380 5.45E-84 T 06-07-2017 SMD11_RS17850 af6572a4d844ceb1c0748c35a55e8931 403 Gene3D G3DSA:3.40.50.2000 7 217 1.3E-47 T 06-07-2017 SMD11_RS17850 af6572a4d844ceb1c0748c35a55e8931 403 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 10 142 8.0E-30 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD11_RS17850 af6572a4d844ceb1c0748c35a55e8931 403 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 10 380 29.889 T 06-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SMD11_RS17850 af6572a4d844ceb1c0748c35a55e8931 403 Gene3D G3DSA:3.40.50.2000 276 358 4.0E-7 T 06-07-2017 SMD11_RS29285 4771c24b0db5ccedd94a39c2819c53a7 274 Pfam PF13560 Helix-turn-helix domain 29 83 9.3E-8 T 06-07-2017 SMD11_RS29285 4771c24b0db5ccedd94a39c2819c53a7 274 Gene3D G3DSA:1.10.260.40 4 81 2.5E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS15460 9a9116a184e815ed151a3d0445ea731b 239 Pfam PF01391 Collagen triple helix repeat (20 copies) 138 192 4.1E-7 T 06-07-2017 IPR008160 Collagen triple helix repeat SMD11_RS18240 94bbc4b42b8dce8a8f5061558aea9fba 32 Pfam PF08213 Mitochondrial domain of unknown function (DUF1713) 2 30 3.0E-9 T 06-07-2017 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18240 94bbc4b42b8dce8a8f5061558aea9fba 32 SMART SM01155 1 32 3.8E-5 T 06-07-2017 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS27520 a5f84ea08eb967e0a14ec5b6cc115936 90 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 14 89 9.9E-10 T 06-07-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 SMD11_RS27520 a5f84ea08eb967e0a14ec5b6cc115936 90 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 7 90 2.7E-24 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 SMD11_RS27520 a5f84ea08eb967e0a14ec5b6cc115936 90 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 3 90 19.628 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 SMD11_RS27520 a5f84ea08eb967e0a14ec5b6cc115936 90 SUPERFAMILY SSF101386 5 90 6.98E-21 T 06-07-2017 SMD11_RS02300 6fc1a59a35db53ac0c8dcda4508f079a 473 SUPERFAMILY SSF48452 16 36 7.59E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS02300 6fc1a59a35db53ac0c8dcda4508f079a 473 SUPERFAMILY SSF48452 152 222 7.59E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS02300 6fc1a59a35db53ac0c8dcda4508f079a 473 Gene3D G3DSA:1.25.40.10 157 265 4.2E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS02300 6fc1a59a35db53ac0c8dcda4508f079a 473 Gene3D G3DSA:1.25.40.10 17 29 4.2E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS02300 6fc1a59a35db53ac0c8dcda4508f079a 473 Gene3D G3DSA:1.25.40.10 397 460 4.2E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS25780 57cc8b04d2e1867f8519c72388060c02 534 Pfam PF13556 PucR C-terminal helix-turn-helix domain 471 529 7.2E-18 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain SMD11_RS25780 57cc8b04d2e1867f8519c72388060c02 534 Gene3D G3DSA:1.10.10.60 478 507 5.3E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS25780 57cc8b04d2e1867f8519c72388060c02 534 Pfam PF07905 Purine catabolism regulatory protein-like family 16 135 1.3E-35 T 06-07-2017 IPR012914 Purine catabolism PurC-like domain SMD11_RS00715 3f0ca63411347cbada177d9f4d558480 121 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 2 66 2.5E-7 T 06-07-2017 IPR018727 Protein of unknown function DUF2267 SMD11_RS02335 c655814462e1c733337056bbd0d919f6 270 SUPERFAMILY SSF53335 82 257 2.94E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS02335 c655814462e1c733337056bbd0d919f6 270 Pfam PF13649 Methyltransferase domain 88 177 5.3E-12 T 06-07-2017 SMD11_RS02335 c655814462e1c733337056bbd0d919f6 270 Gene3D G3DSA:3.40.50.150 79 189 5.6E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS14040 3881652d8058dfd6c70b56c5c827e219 185 Pfam PF13527 Acetyltransferase (GNAT) domain 34 127 8.4E-10 T 06-07-2017 SMD11_RS14040 3881652d8058dfd6c70b56c5c827e219 185 Gene3D G3DSA:3.40.630.30 2 134 2.2E-15 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS14040 3881652d8058dfd6c70b56c5c827e219 185 SUPERFAMILY SSF55729 3 130 1.6E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS13200 3261ea64b2047a36bf8e5c3abb535160 409 PIRSF PIRSF000108 1 405 1.1E-218 T 06-07-2017 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SMD11_RS13200 3261ea64b2047a36bf8e5c3abb535160 409 SUPERFAMILY SSF53659 1 403 2.88E-151 T 06-07-2017 SMD11_RS13200 3261ea64b2047a36bf8e5c3abb535160 409 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 3 403 2.8E-207 T 06-07-2017 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 SMD11_RS13200 3261ea64b2047a36bf8e5c3abb535160 409 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 394 2.4E-69 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMD11_RS13200 3261ea64b2047a36bf8e5c3abb535160 409 Gene3D G3DSA:3.40.718.10 3 402 1.3E-170 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMD11_RS13200 3261ea64b2047a36bf8e5c3abb535160 409 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 270 289 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 SMD11_RS13200 3261ea64b2047a36bf8e5c3abb535160 409 SMART SM01329 9 395 6.0E-134 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 SMD11_RS12880 d0fefb162085c74680db856991e04d58 402 Pfam PF01757 Acyltransferase family 47 373 6.1E-20 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 SMD11_RS08300 c9b66589b2b547d14a24b861c6dd24a3 286 Pfam PF01061 ABC-2 type transporter 36 240 4.5E-27 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD11_RS02930 78a2ec6e6b91f0b83db156e093893053 254 SUPERFAMILY SSF117396 1 239 1.12E-75 T 06-07-2017 IPR002763 Protein of unknown function DUF72 SMD11_RS02930 78a2ec6e6b91f0b83db156e093893053 254 Pfam PF01904 Protein of unknown function DUF72 20 237 2.1E-57 T 06-07-2017 IPR002763 Protein of unknown function DUF72 SMD11_RS02930 78a2ec6e6b91f0b83db156e093893053 254 Gene3D G3DSA:3.20.20.410 2 239 6.7E-76 T 06-07-2017 IPR002763 Protein of unknown function DUF72 SMD11_RS15885 8df7de7a0433d5cbfbf20cb4333f2876 748 SMART SM01236 564 673 8.8E-29 T 06-07-2017 SMD11_RS15885 8df7de7a0433d5cbfbf20cb4333f2876 748 Pfam PF14518 Iron-containing redox enzyme 535 696 1.0E-16 T 06-07-2017 IPR028201 PqqC-like protein SMD11_RS09790 b30f5b2909bf26f50754b7fd2eb76a28 240 PRINTS PR01727 Prokaryotic integration host factor signature 73 87 5.7E-13 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD11_RS09790 b30f5b2909bf26f50754b7fd2eb76a28 240 PRINTS PR01727 Prokaryotic integration host factor signature 39 54 5.7E-13 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD11_RS09790 b30f5b2909bf26f50754b7fd2eb76a28 240 PRINTS PR01727 Prokaryotic integration host factor signature 57 70 5.7E-13 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD11_RS09790 b30f5b2909bf26f50754b7fd2eb76a28 240 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 45 64 - T 06-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 SMD11_RS09790 b30f5b2909bf26f50754b7fd2eb76a28 240 SUPERFAMILY SSF47729 1 92 2.5E-24 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMD11_RS09790 b30f5b2909bf26f50754b7fd2eb76a28 240 Pfam PF00216 Bacterial DNA-binding protein 1 88 4.1E-23 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD11_RS09790 b30f5b2909bf26f50754b7fd2eb76a28 240 Gene3D G3DSA:4.10.520.10 1 89 3.6E-27 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SMD11_RS09790 b30f5b2909bf26f50754b7fd2eb76a28 240 SMART SM00411 1 89 1.3E-38 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 SMD11_RS24605 5e188ab6dfbb46e8048c225af5c7170e 547 SUPERFAMILY SSF56300 150 516 3.42E-31 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS24605 5e188ab6dfbb46e8048c225af5c7170e 547 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 45 141 3.9E-33 T 06-07-2017 IPR032093 Phospholipase D, N-terminal SMD11_RS24605 5e188ab6dfbb46e8048c225af5c7170e 547 Pfam PF09423 PhoD-like phosphatase 154 511 7.6E-115 T 06-07-2017 IPR018946 Alkaline phosphatase D-related SMD11_RS24605 5e188ab6dfbb46e8048c225af5c7170e 547 Gene3D G3DSA:3.60.21.10 160 516 4.0E-12 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS33800 078e9190501fadf4d2351dc33fba49b0 180 SUPERFAMILY SSF54593 1 137 8.25E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS33800 078e9190501fadf4d2351dc33fba49b0 180 Gene3D G3DSA:3.10.180.10 4 134 1.2E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS33800 078e9190501fadf4d2351dc33fba49b0 180 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 128 2.5E-6 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS24980 b4b487290fec596792383697516a1c7b 313 PIRSF PIRSF028754 12 313 2.6E-106 T 06-07-2017 IPR008492 Protein of unknown function DUF774 SMD11_RS24980 b4b487290fec596792383697516a1c7b 313 Gene3D G3DSA:1.10.287.100 237 275 3.8E-8 T 06-07-2017 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 SMD11_RS24980 b4b487290fec596792383697516a1c7b 313 Pfam PF09754 PAC2 family 35 253 1.8E-38 T 06-07-2017 IPR019151 Proteasome assembly chaperone 2 SMD11_RS24980 b4b487290fec596792383697516a1c7b 313 SUPERFAMILY SSF159659 27 276 1.7E-72 T 06-07-2017 SMD11_RS30225 79aad9ee1dd18586d5e4b62abf1f66df 1182 Gene3D G3DSA:3.40.50.300 134 157 1.3E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30225 79aad9ee1dd18586d5e4b62abf1f66df 1182 Pfam PF05729 NACHT domain 135 261 1.9E-8 T 06-07-2017 SMD11_RS30225 79aad9ee1dd18586d5e4b62abf1f66df 1182 Pfam PF12770 CHAT domain 997 1173 7.0E-16 T 06-07-2017 IPR024983 CHAT domain SMD11_RS30225 79aad9ee1dd18586d5e4b62abf1f66df 1182 SUPERFAMILY SSF52540 113 265 1.96E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02485 1245c5ec8be02426a80708868c8b03e6 79 SMART SM00823 Phosphopantetheine attachment site 1 73 0.0021 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS02485 1245c5ec8be02426a80708868c8b03e6 79 Gene3D G3DSA:1.10.1200.10 2 74 7.8E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS02485 1245c5ec8be02426a80708868c8b03e6 79 SUPERFAMILY SSF47336 2 75 4.84E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS02485 1245c5ec8be02426a80708868c8b03e6 79 Pfam PF00550 Phosphopantetheine attachment site 3 68 1.8E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS19455 38eafbfd3ff26e267b4a8ca1dd43ff8b 356 Pfam PF00296 Luciferase-like monooxygenase 70 286 1.6E-47 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS19455 38eafbfd3ff26e267b4a8ca1dd43ff8b 356 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 80 329 3.0E-65 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted SMD11_RS19455 38eafbfd3ff26e267b4a8ca1dd43ff8b 356 SUPERFAMILY SSF51679 65 354 8.77E-61 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS19455 38eafbfd3ff26e267b4a8ca1dd43ff8b 356 Gene3D G3DSA:3.20.20.30 47 354 3.5E-65 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS03340 f645ca9efea3f0d85bf12f79c42b8bef 536 Gene3D G3DSA:3.30.43.10 60 118 9.8E-9 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS03340 f645ca9efea3f0d85bf12f79c42b8bef 536 SUPERFAMILY SSF56176 39 234 9.81E-34 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS03340 f645ca9efea3f0d85bf12f79c42b8bef 536 Gene3D G3DSA:3.30.465.10 124 234 1.8E-5 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS03340 f645ca9efea3f0d85bf12f79c42b8bef 536 Pfam PF01565 FAD binding domain 62 189 6.5E-19 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD11_RS03340 f645ca9efea3f0d85bf12f79c42b8bef 536 Pfam PF08031 Berberine and berberine like 478 530 1.7E-16 T 06-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 SMD11_RS15525 1c66408963cc979f977b91471be7757f 52 Pfam PF13783 Domain of unknown function (DUF4177) 4 50 2.0E-6 T 06-07-2017 IPR025234 Protein of unknown function DUF4177 SMD11_RS23740 eebdf30a6112ab69ea25630759dc12a7 246 SUPERFAMILY SSF48613 31 240 1.53E-59 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS23740 eebdf30a6112ab69ea25630759dc12a7 246 PRINTS PR00088 Haem oxygenase signature 191 212 1.8E-29 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS23740 eebdf30a6112ab69ea25630759dc12a7 246 PRINTS PR00088 Haem oxygenase signature 32 57 1.8E-29 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS23740 eebdf30a6112ab69ea25630759dc12a7 246 PRINTS PR00088 Haem oxygenase signature 94 119 1.8E-29 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS23740 eebdf30a6112ab69ea25630759dc12a7 246 PRINTS PR00088 Haem oxygenase signature 223 241 1.8E-29 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS23740 eebdf30a6112ab69ea25630759dc12a7 246 PRINTS PR00088 Haem oxygenase signature 147 168 1.8E-29 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS23740 eebdf30a6112ab69ea25630759dc12a7 246 Gene3D G3DSA:1.20.910.10 29 239 3.3E-63 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS23740 eebdf30a6112ab69ea25630759dc12a7 246 Pfam PF01126 Heme oxygenase 32 237 5.0E-63 T 06-07-2017 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS23740 eebdf30a6112ab69ea25630759dc12a7 246 PIRSF PIRSF000343 21 245 5.7E-67 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 SMD11_RS23800 14a4a7182cfe155b844c869394b6a1e2 533 SUPERFAMILY SSF103473 485 510 1.31E-72 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS23800 14a4a7182cfe155b844c869394b6a1e2 533 SUPERFAMILY SSF103473 259 430 1.31E-72 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS23800 14a4a7182cfe155b844c869394b6a1e2 533 SUPERFAMILY SSF103473 12 207 1.31E-72 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS23800 14a4a7182cfe155b844c869394b6a1e2 533 Pfam PF07690 Major Facilitator Superfamily 24 420 4.6E-56 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS23800 14a4a7182cfe155b844c869394b6a1e2 533 Gene3D G3DSA:1.20.1250.20 14 204 2.9E-31 T 06-07-2017 SMD11_RS23800 14a4a7182cfe155b844c869394b6a1e2 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 411 430 7.9E-7 T 06-07-2017 SMD11_RS23800 14a4a7182cfe155b844c869394b6a1e2 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 7.9E-7 T 06-07-2017 SMD11_RS23800 14a4a7182cfe155b844c869394b6a1e2 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 313 337 7.9E-7 T 06-07-2017 SMD11_RS23800 14a4a7182cfe155b844c869394b6a1e2 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 23 47 7.9E-7 T 06-07-2017 SMD11_RS23800 14a4a7182cfe155b844c869394b6a1e2 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 7.9E-7 T 06-07-2017 SMD11_RS23800 14a4a7182cfe155b844c869394b6a1e2 533 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 503 3.3E-81 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS23800 14a4a7182cfe155b844c869394b6a1e2 533 Gene3D G3DSA:1.20.1250.20 274 434 2.1E-25 T 06-07-2017 SMD11_RS23800 14a4a7182cfe155b844c869394b6a1e2 533 Gene3D G3DSA:1.20.1250.20 490 513 2.1E-25 T 06-07-2017 SMD11_RS24810 bacec1db16321a8bbf165cc9659a2b7a 612 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 330 597 2.7E-61 T 06-07-2017 IPR018763 Protein of unknown function DUF2334 SMD11_RS33790 b394f8c7211bf8682ed7eb7bcbff44f0 1216 Pfam PF12770 CHAT domain 886 1188 2.4E-26 T 06-07-2017 IPR024983 CHAT domain SMD11_RS29565 0e8f6e92798e2d7575ad5111d41791b7 141 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 24 73 2.2E-19 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS29565 0e8f6e92798e2d7575ad5111d41791b7 141 SUPERFAMILY SSF69118 3 138 3.07E-44 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS29565 0e8f6e92798e2d7575ad5111d41791b7 141 Pfam PF02627 Carboxymuconolactone decarboxylase family 8 88 1.3E-22 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS29565 0e8f6e92798e2d7575ad5111d41791b7 141 Gene3D G3DSA:1.20.1290.10 4 139 3.2E-50 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS03530 992bde25777f9f98e5819db7f8d3fbf9 250 Pfam PF02754 Cysteine-rich domain 3 83 3.9E-15 T 06-07-2017 IPR004017 Cysteine-rich domain SMD11_RS03530 992bde25777f9f98e5819db7f8d3fbf9 250 Pfam PF02754 Cysteine-rich domain 138 222 4.4E-15 T 06-07-2017 IPR004017 Cysteine-rich domain SMD11_RS04570 f4757df6d24e50694bef2ef59735b0ac 274 Gene3D G3DSA:3.40.50.150 6 274 6.3E-104 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS04570 f4757df6d24e50694bef2ef59735b0ac 274 Pfam PF04672 S-adenosyl methyltransferase 12 274 2.3E-96 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD11_RS04570 f4757df6d24e50694bef2ef59735b0ac 274 SUPERFAMILY SSF53335 13 258 4.16E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS04570 f4757df6d24e50694bef2ef59735b0ac 274 PIRSF PIRSF017393 1 274 1.8E-89 T 06-07-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type SMD11_RS05825 ff9856cf7533f503f5e09cf1579ca7ac 456 Gene3D G3DSA:1.10.579.10 276 445 1.0E-67 T 06-07-2017 SMD11_RS05825 ff9856cf7533f503f5e09cf1579ca7ac 456 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 333 352 - T 06-07-2017 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal SMD11_RS05825 ff9856cf7533f503f5e09cf1579ca7ac 456 SUPERFAMILY SSF52425 4 187 1.83E-32 T 06-07-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SMD11_RS05825 ff9856cf7533f503f5e09cf1579ca7ac 456 Pfam PF03441 FAD binding domain of DNA photolyase 266 444 1.9E-69 T 06-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SMD11_RS05825 ff9856cf7533f503f5e09cf1579ca7ac 456 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 313 325 - T 06-07-2017 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal SMD11_RS05825 ff9856cf7533f503f5e09cf1579ca7ac 456 Pfam PF00875 DNA photolyase 5 165 1.4E-34 T 06-07-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SMD11_RS05825 ff9856cf7533f503f5e09cf1579ca7ac 456 PRINTS PR00147 DNA photolyase signature 141 157 8.8E-25 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 SMD11_RS05825 ff9856cf7533f503f5e09cf1579ca7ac 456 PRINTS PR00147 DNA photolyase signature 313 329 8.8E-25 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 SMD11_RS05825 ff9856cf7533f503f5e09cf1579ca7ac 456 PRINTS PR00147 DNA photolyase signature 333 351 8.8E-25 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 SMD11_RS05825 ff9856cf7533f503f5e09cf1579ca7ac 456 PRINTS PR00147 DNA photolyase signature 372 386 8.8E-25 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 SMD11_RS05825 ff9856cf7533f503f5e09cf1579ca7ac 456 Gene3D G3DSA:3.40.50.620 3 147 1.1E-33 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS05825 ff9856cf7533f503f5e09cf1579ca7ac 456 SUPERFAMILY SSF48173 194 446 2.22E-92 T 06-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 SMD11_RS05825 ff9856cf7533f503f5e09cf1579ca7ac 456 Gene3D G3DSA:1.25.40.80 148 275 1.6E-32 T 06-07-2017 SMD11_RS17095 108b04bf0b175865e268816257df1cb0 270 Gene3D G3DSA:1.10.287.110 137 175 6.5E-4 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS17095 108b04bf0b175865e268816257df1cb0 270 SUPERFAMILY SSF46565 134 175 5.5E-5 T 06-07-2017 IPR001623 DnaJ domain SMD11_RS01725 1482e713098b68a7363cddff9c9c4e62 152 SUPERFAMILY SSF51182 6 150 2.22E-47 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS01725 1482e713098b68a7363cddff9c9c4e62 152 Pfam PF06172 Cupin superfamily (DUF985) 10 147 1.6E-42 T 06-07-2017 IPR009327 Cupin domain of unknown function DUF985 SMD11_RS01725 1482e713098b68a7363cddff9c9c4e62 152 Gene3D G3DSA:2.60.120.10 4 149 2.5E-47 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS09890 1781505d277fa6d61ab18d54c3f495c4 193 Pfam PF03029 Conserved hypothetical ATP binding protein 21 188 7.3E-27 T 06-07-2017 IPR004130 GPN-loop GTPase SMD11_RS09890 1781505d277fa6d61ab18d54c3f495c4 193 Gene3D G3DSA:3.40.50.300 13 182 1.3E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09890 1781505d277fa6d61ab18d54c3f495c4 193 SUPERFAMILY SSF52540 16 190 3.85E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22910 6d90944936ac132d5ba035998462c627 334 Pfam PF00248 Aldo/keto reductase family 16 311 6.0E-63 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS22910 6d90944936ac132d5ba035998462c627 334 SUPERFAMILY SSF51430 4 311 1.26E-87 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS22910 6d90944936ac132d5ba035998462c627 334 Gene3D G3DSA:3.20.20.100 3 325 1.3E-94 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS17600 3acc2fe659cfd5d740657b3ccc2c7e4d 212 SUPERFAMILY SSF58014 47 133 4.71E-18 T 06-07-2017 SMD11_RS17600 3acc2fe659cfd5d740657b3ccc2c7e4d 212 PRINTS PR00773 GrpE protein signature 141 156 8.0E-25 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMD11_RS17600 3acc2fe659cfd5d740657b3ccc2c7e4d 212 PRINTS PR00773 GrpE protein signature 66 82 8.0E-25 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMD11_RS17600 3acc2fe659cfd5d740657b3ccc2c7e4d 212 PRINTS PR00773 GrpE protein signature 94 109 8.0E-25 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMD11_RS17600 3acc2fe659cfd5d740657b3ccc2c7e4d 212 PRINTS PR00773 GrpE protein signature 168 187 8.0E-25 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMD11_RS17600 3acc2fe659cfd5d740657b3ccc2c7e4d 212 Gene3D G3DSA:2.30.22.10 133 190 6.1E-22 T 06-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 SMD11_RS17600 3acc2fe659cfd5d740657b3ccc2c7e4d 212 Pfam PF01025 GrpE 45 189 2.6E-35 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMD11_RS17600 3acc2fe659cfd5d740657b3ccc2c7e4d 212 Hamap MF_01151 Protein GrpE [grpE]. 3 189 17.396 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMD11_RS17600 3acc2fe659cfd5d740657b3ccc2c7e4d 212 ProSitePatterns PS01071 grpE protein signature. 144 187 - T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SMD11_RS17600 3acc2fe659cfd5d740657b3ccc2c7e4d 212 SUPERFAMILY SSF51064 135 190 4.32E-16 T 06-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 SMD11_RS17600 3acc2fe659cfd5d740657b3ccc2c7e4d 212 Gene3D G3DSA:3.90.20.20 47 132 3.6E-20 T 06-07-2017 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 SMD11_RS16240 d1ff807de0c5590ae05ec068b93fd84d 153 SUPERFAMILY SSF69118 11 147 6.02E-38 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS16240 d1ff807de0c5590ae05ec068b93fd84d 153 Pfam PF02627 Carboxymuconolactone decarboxylase family 14 94 1.1E-15 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS16240 d1ff807de0c5590ae05ec068b93fd84d 153 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 29 79 1.5E-11 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS16240 d1ff807de0c5590ae05ec068b93fd84d 153 Gene3D G3DSA:1.20.1290.10 13 148 1.3E-45 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS14575 45719ae651aff858faf4cbd22f1c69cb 206 Pfam PF01865 Protein of unknown function DUF47 7 203 8.6E-30 T 06-07-2017 IPR018445 Putative phosphate transport regulator SMD11_RS14575 45719ae651aff858faf4cbd22f1c69cb 206 SUPERFAMILY SSF109755 39 199 9.29E-5 T 06-07-2017 SMD11_RS07485 e3e9e719efb431c26e6c3469161147f6 761 SUPERFAMILY SSF158472 708 755 1.83E-5 T 06-07-2017 SMD11_RS07485 e3e9e719efb431c26e6c3469161147f6 761 Pfam PF00672 HAMP domain 689 755 1.5E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS07485 e3e9e719efb431c26e6c3469161147f6 761 Pfam PF00672 HAMP domain 321 385 5.3E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SMD11_RS17130 d8b9e3c9da9aa2db8e604e5708531f94 320 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 15 303 3.4E-158 T 06-07-2017 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 SMD11_RS17130 d8b9e3c9da9aa2db8e604e5708531f94 320 Pfam PF05138 Phenylacetic acid catabolic protein 25 299 1.1E-107 T 06-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 SMD11_RS17130 d8b9e3c9da9aa2db8e604e5708531f94 320 Gene3D G3DSA:1.20.1260.10 25 280 6.3E-107 T 06-07-2017 IPR012347 Ferritin-related SMD11_RS17130 d8b9e3c9da9aa2db8e604e5708531f94 320 SUPERFAMILY SSF47240 35 278 3.04E-85 T 06-07-2017 IPR009078 Ferritin-like superfamily SMD11_RS16815 cc71f7ce19a6807ac7d7cef5caf1adda 422 Gene3D G3DSA:1.20.1250.20 243 416 2.4E-10 T 06-07-2017 SMD11_RS16815 cc71f7ce19a6807ac7d7cef5caf1adda 422 Gene3D G3DSA:1.20.1250.20 15 201 1.1E-7 T 06-07-2017 SMD11_RS16815 cc71f7ce19a6807ac7d7cef5caf1adda 422 SUPERFAMILY SSF103473 16 421 1.57E-27 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS31750 52d09a26d563f0b054c37fd415f70ca1 145 Gene3D G3DSA:3.90.79.10 15 139 2.7E-21 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS31750 52d09a26d563f0b054c37fd415f70ca1 145 SUPERFAMILY SSF55811 11 141 2.17E-24 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS31750 52d09a26d563f0b054c37fd415f70ca1 145 ProSitePatterns PS00893 Nudix box signature. 50 71 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD11_RS31750 52d09a26d563f0b054c37fd415f70ca1 145 Pfam PF00293 NUDIX domain 14 127 1.1E-12 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS04105 9275d2d33f4db64db0b31e4224f0c63a 171 Gene3D G3DSA:1.20.120.290 41 154 5.6E-6 T 06-07-2017 IPR023222 PsbQ-like domain SMD11_RS15005 81aa6ab1c7e010f29ade02b59cc1dc3e 198 Gene3D G3DSA:1.10.10.10 4 99 2.1E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15005 81aa6ab1c7e010f29ade02b59cc1dc3e 198 SUPERFAMILY SSF46785 4 177 1.07E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15005 81aa6ab1c7e010f29ade02b59cc1dc3e 198 Pfam PF03551 Transcriptional regulator PadR-like family 8 83 3.0E-11 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal SMD11_RS12820 a7606645cf468f7689a139ae5326c9f8 398 Pfam PF02653 Branched-chain amino acid transport system / permease component 30 322 1.6E-30 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD11_RS11355 8b874ca289be9ba51735f33edff0b549 337 Gene3D G3DSA:1.10.620.20 16 304 1.2E-98 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 SMD11_RS11355 8b874ca289be9ba51735f33edff0b549 337 PIRSF PIRSF000355 3 335 4.5E-100 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS11355 8b874ca289be9ba51735f33edff0b549 337 SUPERFAMILY SSF47240 7 324 7.54E-90 T 06-07-2017 IPR009078 Ferritin-like superfamily SMD11_RS11355 8b874ca289be9ba51735f33edff0b549 337 Pfam PF00268 Ribonucleotide reductase, small chain 16 300 2.1E-81 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SMD11_RS01020 c0159a9d3447f26c23da03dd8620712d 297 SUPERFAMILY SSF51971 131 185 9.77E-11 T 06-07-2017 SMD11_RS01020 c0159a9d3447f26c23da03dd8620712d 297 SUPERFAMILY SSF51971 6 58 9.77E-11 T 06-07-2017 SMD11_RS01020 c0159a9d3447f26c23da03dd8620712d 297 Gene3D G3DSA:3.30.9.10 9 140 6.1E-8 T 06-07-2017 SMD11_RS01020 c0159a9d3447f26c23da03dd8620712d 297 Gene3D G3DSA:3.50.50.60 146 195 1.0E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS01020 c0159a9d3447f26c23da03dd8620712d 297 Pfam PF01266 FAD dependent oxidoreductase 7 180 1.2E-17 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD11_RS27600 03d6de8cf3cbc7b28ae1d18ee033e6dc 449 Gene3D G3DSA:1.20.1250.20 232 410 5.0E-9 T 06-07-2017 SMD11_RS27600 03d6de8cf3cbc7b28ae1d18ee033e6dc 449 SUPERFAMILY SSF103473 30 410 1.7E-26 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS27600 03d6de8cf3cbc7b28ae1d18ee033e6dc 449 Gene3D G3DSA:1.20.1250.20 35 197 6.1E-11 T 06-07-2017 SMD11_RS27705 15a0a8fe9574e74bf2a5ebb2e41ec57c 305 SUPERFAMILY SSF56747 18 195 1.44E-29 T 06-07-2017 SMD11_RS27705 15a0a8fe9574e74bf2a5ebb2e41ec57c 305 SMART SM00943 20 205 1.7E-39 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD11_RS27705 15a0a8fe9574e74bf2a5ebb2e41ec57c 305 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 20 197 3.8E-40 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD11_RS24045 9da1096348430e0cf0d89eebf6731fdd 443 Gene3D G3DSA:3.50.50.60 12 50 1.4E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24045 9da1096348430e0cf0d89eebf6731fdd 443 Gene3D G3DSA:3.50.50.60 217 290 1.4E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24045 9da1096348430e0cf0d89eebf6731fdd 443 Gene3D G3DSA:3.50.50.60 387 429 1.4E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24045 9da1096348430e0cf0d89eebf6731fdd 443 SUPERFAMILY SSF51905 11 298 5.83E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24045 9da1096348430e0cf0d89eebf6731fdd 443 SUPERFAMILY SSF51905 384 427 5.83E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24045 9da1096348430e0cf0d89eebf6731fdd 443 Pfam PF01593 Flavin containing amine oxidoreductase 21 424 1.3E-35 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD11_RS03795 7b10ccba08c93193cde5ab62e781d929 288 Pfam PF01144 Coenzyme A transferase 7 204 7.5E-37 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 SMD11_RS03795 7b10ccba08c93193cde5ab62e781d929 288 SUPERFAMILY SSF100950 4 271 4.19E-69 T 06-07-2017 SMD11_RS03795 7b10ccba08c93193cde5ab62e781d929 288 Gene3D G3DSA:3.40.1080.10 4 118 1.2E-75 T 06-07-2017 SMD11_RS03795 7b10ccba08c93193cde5ab62e781d929 288 Gene3D G3DSA:3.40.1080.10 157 280 1.2E-75 T 06-07-2017 SMD11_RS03795 7b10ccba08c93193cde5ab62e781d929 288 SMART SM00882 6 228 2.5E-32 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 SMD11_RS25070 8fdcb80595dfd0c65207c909923c9759 325 Gene3D G3DSA:3.40.1190.20 2 308 3.0E-62 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS25070 8fdcb80595dfd0c65207c909923c9759 325 Pfam PF00294 pfkB family carbohydrate kinase 2 303 5.1E-43 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB SMD11_RS25070 8fdcb80595dfd0c65207c909923c9759 325 SUPERFAMILY SSF53613 2 306 1.87E-60 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS25070 8fdcb80595dfd0c65207c909923c9759 325 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SMD11_RS12280 f11590df99b2530c15984d2d863bb15f 118 Pfam PF02643 Uncharacterized ACR, COG1430 21 112 8.6E-15 T 06-07-2017 IPR003795 Protein of unknown function DUF192 SMD11_RS01765 8bcab6091795c41df7726a4bc3c224c3 128 Gene3D G3DSA:3.10.180.10 7 116 5.5E-14 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS01765 8bcab6091795c41df7726a4bc3c224c3 128 SUPERFAMILY SSF54593 6 118 3.18E-12 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS20800 58eb2397b2afea6b9235279bcf1fbcde 248 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 22 119 7.8E-19 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SMD11_RS20800 58eb2397b2afea6b9235279bcf1fbcde 248 Gene3D G3DSA:3.30.160.100 21 120 3.0E-25 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SMD11_RS20800 58eb2397b2afea6b9235279bcf1fbcde 248 SUPERFAMILY SSF69754 22 128 3.27E-22 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SMD11_RS20800 58eb2397b2afea6b9235279bcf1fbcde 248 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 172 226 3.0E-20 T 06-07-2017 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal SMD11_RS20800 58eb2397b2afea6b9235279bcf1fbcde 248 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 21 123 5.7E-22 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SMD11_RS20070 f841b75882c0af325c9229c3b7c176a3 529 Pfam PF07501 G5 domain 368 441 4.7E-21 T 06-07-2017 IPR011098 G5 domain SMD11_RS20070 f841b75882c0af325c9229c3b7c176a3 529 SUPERFAMILY SSF53955 450 526 8.44E-22 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS20070 f841b75882c0af325c9229c3b7c176a3 529 Pfam PF06737 Transglycosylase-like domain 450 523 6.4E-22 T 06-07-2017 IPR010618 Transglycosylase-like SMD11_RS20070 f841b75882c0af325c9229c3b7c176a3 529 Gene3D G3DSA:1.10.530.10 429 527 4.8E-29 T 06-07-2017 SMD11_RS20070 f841b75882c0af325c9229c3b7c176a3 529 Pfam PF03990 Domain of unknown function (DUF348) 311 351 3.6E-11 T 06-07-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 SMD11_RS20070 f841b75882c0af325c9229c3b7c176a3 529 Pfam PF03990 Domain of unknown function (DUF348) 197 235 4.3E-9 T 06-07-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 SMD11_RS20070 f841b75882c0af325c9229c3b7c176a3 529 Pfam PF03990 Domain of unknown function (DUF348) 254 291 2.1E-7 T 06-07-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 SMD11_RS20070 f841b75882c0af325c9229c3b7c176a3 529 SMART SM01208 364 442 1.3E-23 T 06-07-2017 IPR011098 G5 domain SMD11_RS22040 0e0434fd05db2b704c9499f6a972380b 134 Gene3D G3DSA:1.10.490.10 11 133 4.2E-46 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 SMD11_RS22040 0e0434fd05db2b704c9499f6a972380b 134 SUPERFAMILY SSF46458 12 133 1.69E-38 T 06-07-2017 IPR009050 Globin-like SMD11_RS22040 0e0434fd05db2b704c9499f6a972380b 134 Pfam PF01152 Bacterial-like globin 13 129 9.4E-35 T 06-07-2017 IPR001486 Truncated hemoglobin GO:0019825 SMD11_RS20710 8590cc080b9398a6b2d715b0348719c0 161 Pfam PF12005 Protein of unknown function (DUF3499) 34 157 2.5E-47 T 06-07-2017 IPR021888 Protein of unknown function DUF3499 SMD11_RS06720 2453154d0615f76e26af798e6e895c18 286 Gene3D G3DSA:1.10.3720.10 62 261 5.6E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS06720 2453154d0615f76e26af798e6e895c18 286 SUPERFAMILY SSF161098 61 249 7.33E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS06720 2453154d0615f76e26af798e6e895c18 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 261 1.7E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS06720 2453154d0615f76e26af798e6e895c18 286 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 62 151 2.3E-17 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMD11_RS00005 06752984e83b09746b5a295f128d9880 433 Gene3D G3DSA:3.40.50.300 298 421 5.6E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00005 06752984e83b09746b5a295f128d9880 433 Gene3D G3DSA:3.40.50.300 23 100 7.2E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00005 06752984e83b09746b5a295f128d9880 433 Gene3D G3DSA:3.40.50.300 146 204 7.2E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00005 06752984e83b09746b5a295f128d9880 433 SMART SM00490 330 421 2.1E-7 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS00005 06752984e83b09746b5a295f128d9880 433 SMART SM00487 19 223 3.6E-4 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS00005 06752984e83b09746b5a295f128d9880 433 Pfam PF04851 Type III restriction enzyme, res subunit 23 201 6.6E-18 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SMD11_RS00005 06752984e83b09746b5a295f128d9880 433 Pfam PF00271 Helicase conserved C-terminal domain 308 420 1.5E-10 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS00005 06752984e83b09746b5a295f128d9880 433 SUPERFAMILY SSF52540 278 421 1.22E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00005 06752984e83b09746b5a295f128d9880 433 SUPERFAMILY SSF52540 38 203 1.22E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03255 3a904077599d74d35b97895601a1d06c 310 SMART SM00062 74 303 1.5E-23 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD11_RS03255 3a904077599d74d35b97895601a1d06c 310 SUPERFAMILY SSF53850 57 301 2.09E-43 T 06-07-2017 SMD11_RS03255 3a904077599d74d35b97895601a1d06c 310 SMART SM00079 74 302 0.0066 T 06-07-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 SMD11_RS03255 3a904077599d74d35b97895601a1d06c 310 Gene3D G3DSA:3.40.190.10 187 253 5.9E-13 T 06-07-2017 SMD11_RS03255 3a904077599d74d35b97895601a1d06c 310 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 75 301 6.0E-37 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD11_RS03255 3a904077599d74d35b97895601a1d06c 310 Gene3D G3DSA:3.40.190.10 42 186 2.3E-23 T 06-07-2017 SMD11_RS15820 cbe8e18eeae1020546a5004ed6f176cd 182 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 9 181 8.7E-31 T 06-07-2017 IPR023869 tRNA adenosine deaminase-associated protein, putative SMD11_RS01780 ec3a85ab6793b487d5a60838b18d80fa 337 Gene3D G3DSA:3.40.50.620 156 296 2.4E-26 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS01780 ec3a85ab6793b487d5a60838b18d80fa 337 Pfam PF02698 DUF218 domain 162 309 3.7E-29 T 06-07-2017 IPR003848 Domain of unknown function DUF218 SMD11_RS13640 ae602b6b49efde0c4b10925868a5760a 357 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 6 260 2.7E-104 T 06-07-2017 IPR017518 Conserved hypothetical protein CHP03084 SMD11_RS13640 ae602b6b49efde0c4b10925868a5760a 357 Pfam PF08608 Wyosine base formation 185 237 7.1E-7 T 06-07-2017 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 SMD11_RS13640 ae602b6b49efde0c4b10925868a5760a 357 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 149 5.6E-32 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD11_RS13640 ae602b6b49efde0c4b10925868a5760a 357 SUPERFAMILY SSF109854 2 154 7.63E-33 T 06-07-2017 SMD11_RS13640 ae602b6b49efde0c4b10925868a5760a 357 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 227 2.2E-48 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD11_RS10840 25660d4704116e94c58a8e20778f837f 215 Gene3D G3DSA:3.90.870.10 5 205 1.9E-64 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain SMD11_RS10840 25660d4704116e94c58a8e20778f837f 215 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 12 207 2.4E-56 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 SMD11_RS10840 25660d4704116e94c58a8e20778f837f 215 Pfam PF01300 Telomere recombination 23 197 4.9E-46 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 SMD11_RS10840 25660d4704116e94c58a8e20778f837f 215 SUPERFAMILY SSF55821 3 210 4.27E-57 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain SMD11_RS01650 d26b53d15579e14661c810194ecd4458 187 SUPERFAMILY SSF55729 8 175 5.85E-34 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS01650 d26b53d15579e14661c810194ecd4458 187 Gene3D G3DSA:3.40.630.30 9 181 1.2E-36 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS01650 d26b53d15579e14661c810194ecd4458 187 Pfam PF13302 Acetyltransferase (GNAT) domain 12 151 5.7E-18 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS06515 04d8aae9662a3720daaa9df5d1ed3ff6 215 Pfam PF02666 Phosphatidylserine decarboxylase 56 208 2.1E-30 T 06-07-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 SMD11_RS06515 04d8aae9662a3720daaa9df5d1ed3ff6 215 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 14 215 32.585 T 06-07-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 SMD11_RS06515 04d8aae9662a3720daaa9df5d1ed3ff6 215 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 43 212 2.5E-53 T 06-07-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 SMD11_RS29110 fc601e43f3ef96951b49102a671b01e8 369 Gene3D G3DSA:3.40.47.10 204 224 6.0E-8 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29110 fc601e43f3ef96951b49102a671b01e8 369 Gene3D G3DSA:3.40.47.10 23 121 6.0E-8 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29110 fc601e43f3ef96951b49102a671b01e8 369 SUPERFAMILY SSF53901 15 128 2.94E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29110 fc601e43f3ef96951b49102a671b01e8 369 SUPERFAMILY SSF53901 186 340 2.94E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29110 fc601e43f3ef96951b49102a671b01e8 369 Gene3D G3DSA:3.40.47.10 157 188 9.6E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29110 fc601e43f3ef96951b49102a671b01e8 369 Gene3D G3DSA:3.40.47.10 236 340 9.6E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS06615 c2bad75662f98ae96da2b7b5ac75a76e 95 Pfam PF13411 MerR HTH family regulatory protein 6 73 1.3E-15 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS06615 c2bad75662f98ae96da2b7b5ac75a76e 95 SUPERFAMILY SSF46955 5 87 2.6E-22 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS06615 c2bad75662f98ae96da2b7b5ac75a76e 95 Gene3D G3DSA:1.10.1660.10 6 91 1.5E-23 T 06-07-2017 SMD11_RS06615 c2bad75662f98ae96da2b7b5ac75a76e 95 SMART SM00422 6 75 4.8E-21 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS06615 c2bad75662f98ae96da2b7b5ac75a76e 95 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 7 18 1.9E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS06615 c2bad75662f98ae96da2b7b5ac75a76e 95 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 1.9E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS06615 c2bad75662f98ae96da2b7b5ac75a76e 95 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 31 1.9E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS08125 18adc174594c629edaad26ac60c95ff6 203 SUPERFAMILY SSF51182 1 195 1.29E-57 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS08125 18adc174594c629edaad26ac60c95ff6 203 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 176 4.4E-43 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 SMD11_RS08125 18adc174594c629edaad26ac60c95ff6 203 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 144 5.0E-58 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 SMD11_RS08125 18adc174594c629edaad26ac60c95ff6 203 Gene3D G3DSA:2.60.120.10 1 190 1.8E-52 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 Pfam PF14759 Reductase C-terminal 333 418 2.0E-17 T 06-07-2017 IPR028202 Reductase, C-terminal SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 SUPERFAMILY SSF51905 153 323 1.99E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 Gene3D G3DSA:3.50.50.60 4 112 1.3E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 SUPERFAMILY SSF51905 4 199 3.11E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 Gene3D G3DSA:3.50.50.60 113 323 9.8E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 314 1.3E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 Gene3D G3DSA:3.30.390.30 333 420 4.6E-31 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 4.4E-25 T 06-07-2017 SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 4.4E-25 T 06-07-2017 SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 4.4E-25 T 06-07-2017 SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 4.4E-25 T 06-07-2017 SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 4.4E-25 T 06-07-2017 SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 284 291 2.2E-16 T 06-07-2017 SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.2E-16 T 06-07-2017 SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 2.2E-16 T 06-07-2017 SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 2.2E-16 T 06-07-2017 SMD11_RS23020 d0cf5c5b36efbbb25c1e75c11d8ea664 421 SUPERFAMILY SSF55424 326 419 2.75E-27 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SMD11_RS08490 5920a861a2dc093dc1eb592827719117 178 Pfam PF13527 Acetyltransferase (GNAT) domain 10 129 9.8E-14 T 06-07-2017 SMD11_RS08490 5920a861a2dc093dc1eb592827719117 178 SUPERFAMILY SSF55729 8 178 2.61E-34 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS08490 5920a861a2dc093dc1eb592827719117 178 Gene3D G3DSA:3.40.630.30 3 178 2.3E-60 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS05465 3747dfedba19472c2b61f9010af41077 268 Gene3D G3DSA:3.10.180.10 139 262 8.4E-33 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS05465 3747dfedba19472c2b61f9010af41077 268 Gene3D G3DSA:3.10.180.10 10 125 3.7E-33 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS05465 3747dfedba19472c2b61f9010af41077 268 SUPERFAMILY SSF54593 10 126 6.58E-19 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS05465 3747dfedba19472c2b61f9010af41077 268 SUPERFAMILY SSF54593 137 264 6.04E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS19540 efc2961f72ea50fd561ee0a10efc98fa 381 Pfam PF03747 ADP-ribosylglycohydrolase 26 328 2.5E-66 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 SMD11_RS19540 efc2961f72ea50fd561ee0a10efc98fa 381 SUPERFAMILY SSF101478 19 348 7.72E-64 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 SMD11_RS11585 67cea2051d322affbb581bd09c95b001 85 Pfam PF00462 Glutaredoxin 5 60 1.2E-12 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 SMD11_RS11585 67cea2051d322affbb581bd09c95b001 85 ProSitePatterns PS00194 Thioredoxin family active site. 5 23 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 SMD11_RS11585 67cea2051d322affbb581bd09c95b001 85 Gene3D G3DSA:3.40.30.10 4 83 3.8E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS11585 67cea2051d322affbb581bd09c95b001 85 TIGRFAM TIGR02200 GlrX_actino: glutaredoxin-like protein 4 84 1.6E-27 T 06-07-2017 IPR011915 Glutaredoxin-like protein, actinobacteria SMD11_RS11585 67cea2051d322affbb581bd09c95b001 85 SUPERFAMILY SSF52833 4 67 2.71E-14 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS24745 9b270e957d22e207c7da4e7b55d192ee 144 Pfam PF10825 Protein of unknown function (DUF2752) 49 97 1.6E-15 T 06-07-2017 IPR021215 Protein of unknown function DUF2752 SMD11_RS04225 e932b26b2d0a61e01215add8419a3ef9 522 Pfam PF13520 Amino acid permease 18 421 2.3E-51 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS04225 e932b26b2d0a61e01215add8419a3ef9 522 PIRSF PIRSF006060 3 488 1.4E-85 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS02440 4278e9c2b596aa0dfbe1221bdb9016d5 143 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 130 73.349 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 SMD11_RS02440 4278e9c2b596aa0dfbe1221bdb9016d5 143 PIRSF PIRSF006246 1 135 2.6E-52 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 SMD11_RS02440 4278e9c2b596aa0dfbe1221bdb9016d5 143 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 2 118 2.4E-48 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 SMD11_RS02440 4278e9c2b596aa0dfbe1221bdb9016d5 143 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 114 3.0E-44 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 SMD11_RS02440 4278e9c2b596aa0dfbe1221bdb9016d5 143 SUPERFAMILY SSF50692 2 115 2.24E-48 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain SMD11_RS02440 4278e9c2b596aa0dfbe1221bdb9016d5 143 Gene3D G3DSA:2.40.40.20 2 117 8.7E-55 T 06-07-2017 SMD11_RS02440 4278e9c2b596aa0dfbe1221bdb9016d5 143 Pfam PF02261 Aspartate decarboxylase 2 114 5.7E-51 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 SMD11_RS29525 b7dc42c74ff92b1827f4188d9f389ad9 494 Pfam PF07690 Major Facilitator Superfamily 2 386 4.9E-43 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS29525 b7dc42c74ff92b1827f4188d9f389ad9 494 SUPERFAMILY SSF103473 1 169 1.83E-36 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS29525 b7dc42c74ff92b1827f4188d9f389ad9 494 Gene3D G3DSA:1.20.1250.20 443 466 4.0E-13 T 06-07-2017 SMD11_RS29525 b7dc42c74ff92b1827f4188d9f389ad9 494 Gene3D G3DSA:1.20.1250.20 2 166 2.5E-26 T 06-07-2017 SMD11_RS29525 b7dc42c74ff92b1827f4188d9f389ad9 494 Gene3D G3DSA:1.20.1250.20 245 397 4.0E-13 T 06-07-2017 SMD11_RS29525 b7dc42c74ff92b1827f4188d9f389ad9 494 SUPERFAMILY SSF103473 442 466 7.19E-22 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS29525 b7dc42c74ff92b1827f4188d9f389ad9 494 SUPERFAMILY SSF103473 185 396 7.19E-22 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS31115 8219e2151debe1b5c62d6c79eed8feb3 407 Pfam PF07690 Major Facilitator Superfamily 9 330 5.6E-32 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS31115 8219e2151debe1b5c62d6c79eed8feb3 407 Gene3D G3DSA:1.20.1250.20 199 380 8.8E-12 T 06-07-2017 SMD11_RS31115 8219e2151debe1b5c62d6c79eed8feb3 407 Gene3D G3DSA:1.20.1250.20 5 182 2.5E-25 T 06-07-2017 SMD11_RS31115 8219e2151debe1b5c62d6c79eed8feb3 407 SUPERFAMILY SSF103473 3 379 2.49E-50 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS27875 fff82ca10a0ed0bf07c69b615632c93c 124 Pfam PF13397 RNA polymerase-binding protein 4 107 1.9E-41 T 06-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 SMD11_RS27875 fff82ca10a0ed0bf07c69b615632c93c 124 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 120 26.542 T 06-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 SMD11_RS01110 fa2217035057e6c392a4de00e2aa3827 355 Pfam PF03741 Integral membrane protein TerC family 70 272 3.3E-52 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 SMD11_RS01110 fa2217035057e6c392a4de00e2aa3827 355 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 5 307 2.2E-115 T 06-07-2017 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 SMD11_RS06470 f893f4d77ae577d97761d54ae06406c6 151 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 146 1.2E-24 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase SMD11_RS06470 f893f4d77ae577d97761d54ae06406c6 151 PIRSF PIRSF017371 1 147 1.1E-71 T 06-07-2017 IPR014488 Uncharacterised conserved protein UCP017371 SMD11_RS06470 f893f4d77ae577d97761d54ae06406c6 151 SUPERFAMILY SSF55961 3 125 8.25E-19 T 06-07-2017 SMD11_RS06470 f893f4d77ae577d97761d54ae06406c6 151 Gene3D G3DSA:3.30.530.20 5 149 6.5E-7 T 06-07-2017 IPR023393 START-like domain SMD11_RS16250 b452986715ba93a35fb422a2c8b3cc27 112 Pfam PF13564 DoxX-like family 7 107 7.0E-20 T 06-07-2017 IPR032808 DoxX family SMD11_RS26750 fd5c62873163c6137fa69a0ea1c22830 176 Gene3D G3DSA:3.90.79.10 2 173 2.3E-35 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS26750 fd5c62873163c6137fa69a0ea1c22830 176 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SMD11_RS26750 fd5c62873163c6137fa69a0ea1c22830 176 Pfam PF00293 NUDIX domain 40 152 1.5E-16 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS26750 fd5c62873163c6137fa69a0ea1c22830 176 SUPERFAMILY SSF55811 3 174 1.76E-38 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS04200 d10c3758417e39392fcba06f40bd97f7 277 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 235 1.9E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS04200 d10c3758417e39392fcba06f40bd97f7 277 Gene3D G3DSA:3.40.50.2300 7 129 5.9E-44 T 06-07-2017 SMD11_RS04200 d10c3758417e39392fcba06f40bd97f7 277 SMART SM00862 160 235 1.1E-29 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS04200 d10c3758417e39392fcba06f40bd97f7 277 SUPERFAMILY SSF46894 142 235 1.3E-28 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS04200 d10c3758417e39392fcba06f40bd97f7 277 SMART SM00448 8 118 3.1E-49 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS04200 d10c3758417e39392fcba06f40bd97f7 277 SUPERFAMILY SSF52172 5 129 4.98E-46 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS04200 d10c3758417e39392fcba06f40bd97f7 277 Gene3D G3DSA:1.10.10.10 140 236 4.7E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04200 d10c3758417e39392fcba06f40bd97f7 277 Pfam PF00072 Response regulator receiver domain 10 118 6.0E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS17540 8afa0fc154ec28a572b82b4e8d2f6a0e 558 SMART SM00220 20 282 2.6E-54 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS17540 8afa0fc154ec28a572b82b4e8d2f6a0e 558 Gene3D G3DSA:1.10.510.10 90 277 2.0E-45 T 06-07-2017 SMD11_RS17540 8afa0fc154ec28a572b82b4e8d2f6a0e 558 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 143 155 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS17540 8afa0fc154ec28a572b82b4e8d2f6a0e 558 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 26 49 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS17540 8afa0fc154ec28a572b82b4e8d2f6a0e 558 Pfam PF00069 Protein kinase domain 20 275 1.6E-44 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS17540 8afa0fc154ec28a572b82b4e8d2f6a0e 558 SUPERFAMILY SSF56112 17 345 3.78E-67 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS17540 8afa0fc154ec28a572b82b4e8d2f6a0e 558 Gene3D G3DSA:3.30.200.20 12 89 1.2E-22 T 06-07-2017 SMD11_RS16405 2fa4467a3bad55d6d258062a39df431e 229 SUPERFAMILY SSF56784 8 212 7.99E-28 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS16405 2fa4467a3bad55d6d258062a39df431e 229 Gene3D G3DSA:3.40.50.1000 83 219 2.1E-34 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS16405 2fa4467a3bad55d6d258062a39df431e 229 Pfam PF12710 haloacid dehalogenase-like hydrolase 9 193 4.4E-29 T 06-07-2017 SMD11_RS16405 2fa4467a3bad55d6d258062a39df431e 229 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 8 194 1.8E-22 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 SMD11_RS16405 2fa4467a3bad55d6d258062a39df431e 229 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 9 203 7.6E-38 T 06-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial SMD11_RS09040 4ec5d23e99da506e7feabea0cd5ba4b1 227 Gene3D G3DSA:3.90.1150.10 103 219 7.4E-23 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS09040 4ec5d23e99da506e7feabea0cd5ba4b1 227 Gene3D G3DSA:3.40.640.10 6 95 1.1E-23 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS09040 4ec5d23e99da506e7feabea0cd5ba4b1 227 SUPERFAMILY SSF53383 6 217 7.52E-35 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS09040 4ec5d23e99da506e7feabea0cd5ba4b1 227 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 6 95 4.7E-27 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMD11_RS09040 4ec5d23e99da506e7feabea0cd5ba4b1 227 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 103 215 8.2E-12 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase SMD11_RS04015 6c36544f68bcd5f6c9f35371f46c4efe 578 SMART SM00382 327 519 9.3E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS04015 6c36544f68bcd5f6c9f35371f46c4efe 578 SUPERFAMILY SSF52540 295 544 6.16E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04015 6c36544f68bcd5f6c9f35371f46c4efe 578 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 521 553 0.041 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS04015 6c36544f68bcd5f6c9f35371f46c4efe 578 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 7 39 0.11 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SMD11_RS04015 6c36544f68bcd5f6c9f35371f46c4efe 578 ProSitePatterns PS00211 ABC transporters family signature. 442 456 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS04015 6c36544f68bcd5f6c9f35371f46c4efe 578 Pfam PF00005 ABC transporter 318 470 4.5E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS04015 6c36544f68bcd5f6c9f35371f46c4efe 578 Gene3D G3DSA:3.40.50.300 298 544 2.8E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS33385 a5fb8b329368934d7540364661705d9e 370 Gene3D G3DSA:1.10.357.10 6 192 1.7E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS33385 a5fb8b329368934d7540364661705d9e 370 SUPERFAMILY SSF46689 3 82 1.85E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS33385 a5fb8b329368934d7540364661705d9e 370 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 7.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS33385 a5fb8b329368934d7540364661705d9e 370 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 7.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS33385 a5fb8b329368934d7540364661705d9e 370 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 2.4E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS34390 afd381ba748ab5fe94333e65ea37f900 299 Pfam PF00535 Glycosyl transferase family 2 7 119 3.3E-16 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD11_RS34390 afd381ba748ab5fe94333e65ea37f900 299 SUPERFAMILY SSF53448 6 230 3.94E-34 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS34390 afd381ba748ab5fe94333e65ea37f900 299 Gene3D G3DSA:3.90.550.10 6 228 3.0E-22 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS26550 15012676e4817114869943e3db6b62cd 299 Gene3D G3DSA:3.10.50.40 194 298 8.9E-10 T 06-07-2017 SMD11_RS26550 15012676e4817114869943e3db6b62cd 299 Gene3D G3DSA:3.10.50.40 38 171 3.2E-42 T 06-07-2017 SMD11_RS26550 15012676e4817114869943e3db6b62cd 299 SUPERFAMILY SSF54534 50 159 1.73E-38 T 06-07-2017 SMD11_RS26550 15012676e4817114869943e3db6b62cd 299 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 67 155 2.0E-26 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 SMD11_RS26550 15012676e4817114869943e3db6b62cd 299 SUPERFAMILY SSF54534 186 298 4.91E-12 T 06-07-2017 SMD11_RS05695 6f29ad9dea629ab37d0604df93875ac0 310 SUPERFAMILY SSF102114 14 256 5.36E-40 T 06-07-2017 SMD11_RS05695 6f29ad9dea629ab37d0604df93875ac0 310 Pfam PF13186 Iron-sulfur cluster-binding domain 210 270 2.7E-9 T 06-07-2017 IPR023885 4Fe4S-binding SPASM domain SMD11_RS05695 6f29ad9dea629ab37d0604df93875ac0 310 Pfam PF04055 Radical SAM superfamily 21 160 5.2E-16 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS05695 6f29ad9dea629ab37d0604df93875ac0 310 Gene3D G3DSA:3.20.20.70 13 280 1.7E-38 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS24135 c41ca101a1e83e33caa91b67947ce922 199 Pfam PF11241 Protein of unknown function (DUF3043) 31 197 2.6E-60 T 06-07-2017 IPR021403 Protein of unknown function DUF3043 SMD11_RS12065 aa4193135a634ed775dbd486637fd2ce 672 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 27 136 2.2E-11 T 06-07-2017 IPR007621 TPM domain SMD11_RS09620 35c69556e92618a55c4759cf83e97fc4 277 SUPERFAMILY SSF53335 25 207 1.86E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS09620 35c69556e92618a55c4759cf83e97fc4 277 Gene3D G3DSA:3.40.50.150 37 276 1.5E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS07340 781f18a014c237ba370b60937c3e1383 243 Gene3D G3DSA:3.40.50.300 20 242 4.0E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07340 781f18a014c237ba370b60937c3e1383 243 SMART SM00382 50 239 1.2E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS07340 781f18a014c237ba370b60937c3e1383 243 Pfam PF00005 ABC transporter 41 191 1.7E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS07340 781f18a014c237ba370b60937c3e1383 243 SUPERFAMILY SSF52540 22 242 3.66E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS07340 781f18a014c237ba370b60937c3e1383 243 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS16655 03a9139baa66e1e59d9bd17786b517c8 172 Gene3D G3DSA:3.90.79.10 2 125 2.3E-15 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS16655 03a9139baa66e1e59d9bd17786b517c8 172 SUPERFAMILY SSF55811 33 125 7.99E-15 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS16655 03a9139baa66e1e59d9bd17786b517c8 172 Pfam PF00293 NUDIX domain 34 125 2.6E-10 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS20120 bec0c9a2cc5c3ba526e25ec345124715 326 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 11 322 3.7E-112 T 06-07-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 SMD11_RS20120 bec0c9a2cc5c3ba526e25ec345124715 326 SUPERFAMILY SSF51735 8 321 2.51E-87 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20120 bec0c9a2cc5c3ba526e25ec345124715 326 Gene3D G3DSA:3.40.50.720 4 174 3.6E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20120 bec0c9a2cc5c3ba526e25ec345124715 326 Gene3D G3DSA:3.90.25.10 175 322 5.8E-43 T 06-07-2017 SMD11_RS20120 bec0c9a2cc5c3ba526e25ec345124715 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 11 246 3.7E-55 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 SMART SM00831 39 112 4.9E-10 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 SUPERFAMILY SSF56784 550 706 2.64E-36 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 SUPERFAMILY SSF81665 278 371 1.83E-91 T 06-07-2017 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 SUPERFAMILY SSF81665 41 158 1.83E-91 T 06-07-2017 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 SUPERFAMILY SSF81665 709 917 1.83E-91 T 06-07-2017 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 Gene3D G3DSA:2.70.150.10 153 277 7.2E-30 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 Gene3D G3DSA:2.70.150.10 55 91 7.2E-30 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 Pfam PF00122 E1-E2 ATPase 126 368 2.4E-53 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 29 919 0.0 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 736 747 2.5E-79 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 307 326 2.5E-79 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 873 894 2.5E-79 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 718 733 2.5E-79 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 290 306 2.5E-79 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 411 424 2.5E-79 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 768 781 2.5E-79 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 823 844 2.5E-79 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 788 804 2.5E-79 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 Pfam PF00690 Cation transporter/ATPase, N-terminus 41 106 4.3E-11 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 275 413 6.6E-22 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 630 749 7.4E-29 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 Pfam PF00702 haloacid dehalogenase-like hydrolase 373 674 4.8E-15 T 06-07-2017 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 SUPERFAMILY SSF81660 344 563 4.12E-37 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 379 385 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 Gene3D G3DSA:1.20.1110.10 92 152 1.6E-62 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 Gene3D G3DSA:1.20.1110.10 629 910 1.6E-62 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 SUPERFAMILY SSF81653 173 276 2.75E-24 T 06-07-2017 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 Pfam PF00689 Cation transporting ATPase, C-terminus 744 909 2.8E-14 T 06-07-2017 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 SMD11_RS07060 ee1df32b55475730c1016841f6aff28f 920 Gene3D G3DSA:3.40.1110.10 369 567 2.1E-36 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SMD11_RS07580 cb198ef3d35023a5565fede3d0438aad 466 TIGRFAM TIGR03851 chitin_NgcE: carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein 14 463 1.5E-191 T 06-07-2017 IPR022386 Carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding SMD11_RS07580 cb198ef3d35023a5565fede3d0438aad 466 Pfam PF13416 Bacterial extracellular solute-binding protein 71 379 2.7E-23 T 06-07-2017 SMD11_RS07580 cb198ef3d35023a5565fede3d0438aad 466 SUPERFAMILY SSF53850 20 463 3.85E-57 T 06-07-2017 SMD11_RS07580 cb198ef3d35023a5565fede3d0438aad 466 Gene3D G3DSA:3.40.190.10 174 374 1.6E-35 T 06-07-2017 SMD11_RS15245 10677b0c9cb44e1901eca9edced356aa 69 SUPERFAMILY SSF46955 12 60 3.48E-5 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS15245 10677b0c9cb44e1901eca9edced356aa 69 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 12 58 1.4E-15 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMD11_RS15245 10677b0c9cb44e1901eca9edced356aa 69 Pfam PF12728 Helix-turn-helix domain 12 59 2.3E-16 T 06-07-2017 SMD11_RS22915 8747bc023000724109c9058771faf884 449 SUPERFAMILY SSF103473 3 184 1.44E-53 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS22915 8747bc023000724109c9058771faf884 449 SUPERFAMILY SSF103473 238 444 1.44E-53 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS22915 8747bc023000724109c9058771faf884 449 Pfam PF07690 Major Facilitator Superfamily 3 402 5.1E-39 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS22915 8747bc023000724109c9058771faf884 449 Gene3D G3DSA:1.20.1250.20 5 183 7.5E-29 T 06-07-2017 SMD11_RS22915 8747bc023000724109c9058771faf884 449 Gene3D G3DSA:1.20.1250.20 267 441 9.8E-8 T 06-07-2017 SMD11_RS19450 aa6f18974f6ef5f0773e87d5aeaa1299 409 Pfam PF04909 Amidohydrolase 99 397 2.9E-41 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 SMD11_RS19450 aa6f18974f6ef5f0773e87d5aeaa1299 409 Gene3D G3DSA:3.20.20.140 85 398 2.7E-65 T 06-07-2017 SMD11_RS19450 aa6f18974f6ef5f0773e87d5aeaa1299 409 Gene3D G3DSA:3.20.20.140 6 34 2.7E-65 T 06-07-2017 SMD11_RS19450 aa6f18974f6ef5f0773e87d5aeaa1299 409 SUPERFAMILY SSF51556 6 35 3.47E-70 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS19450 aa6f18974f6ef5f0773e87d5aeaa1299 409 SUPERFAMILY SSF51556 88 397 3.47E-70 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS04145 a93145100806c26d6d45a66d62ceff54 365 Gene3D G3DSA:1.10.10.10 33 114 1.4E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04145 a93145100806c26d6d45a66d62ceff54 365 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 1.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS04145 a93145100806c26d6d45a66d62ceff54 365 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 61 71 1.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS04145 a93145100806c26d6d45a66d62ceff54 365 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 71 82 1.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS04145 a93145100806c26d6d45a66d62ceff54 365 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 35 94 1.7E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SMD11_RS04145 a93145100806c26d6d45a66d62ceff54 365 SUPERFAMILY SSF53850 124 320 1.81E-21 T 06-07-2017 SMD11_RS04145 a93145100806c26d6d45a66d62ceff54 365 Gene3D G3DSA:3.40.190.10 125 202 1.2E-6 T 06-07-2017 SMD11_RS04145 a93145100806c26d6d45a66d62ceff54 365 Gene3D G3DSA:3.40.190.10 203 289 3.2E-9 T 06-07-2017 SMD11_RS04145 a93145100806c26d6d45a66d62ceff54 365 SUPERFAMILY SSF46785 32 112 8.17E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04145 a93145100806c26d6d45a66d62ceff54 365 Pfam PF03466 LysR substrate binding domain 122 311 7.7E-23 T 06-07-2017 IPR005119 LysR, substrate-binding SMD11_RS12455 0164863e10e061a7eb8feb667c5fc0aa 283 Pfam PF01061 ABC-2 type transporter 26 236 1.3E-28 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD11_RS12455 0164863e10e061a7eb8feb667c5fc0aa 283 PIRSF PIRSF006648 5 283 2.2E-75 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS12515 6d339fbe534e8d107860167c8052a066 217 Gene3D G3DSA:3.90.226.10 30 203 6.2E-71 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS12515 6d339fbe534e8d107860167c8052a066 217 Pfam PF00574 Clp protease 30 202 5.9E-72 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SMD11_RS12515 6d339fbe534e8d107860167c8052a066 217 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 122 135 - T 06-07-2017 IPR033135 ClpP, histidine active site SMD11_RS12515 6d339fbe534e8d107860167c8052a066 217 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 12 203 37.885 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS12515 6d339fbe534e8d107860167c8052a066 217 PRINTS PR00127 Clp protease catalytic subunit P signature 178 197 1.6E-41 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS12515 6d339fbe534e8d107860167c8052a066 217 PRINTS PR00127 Clp protease catalytic subunit P signature 29 44 1.6E-41 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS12515 6d339fbe534e8d107860167c8052a066 217 PRINTS PR00127 Clp protease catalytic subunit P signature 121 140 1.6E-41 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS12515 6d339fbe534e8d107860167c8052a066 217 PRINTS PR00127 Clp protease catalytic subunit P signature 69 89 1.6E-41 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS12515 6d339fbe534e8d107860167c8052a066 217 PRINTS PR00127 Clp protease catalytic subunit P signature 100 117 1.6E-41 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SMD11_RS12515 6d339fbe534e8d107860167c8052a066 217 SUPERFAMILY SSF52096 31 204 1.12E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS23345 184756a9db7a88ad160c7eaf411c4ef8 193 Pfam PF01169 Uncharacterized protein family UPF0016 10 79 5.6E-15 T 06-07-2017 IPR001727 Gdt1 family GO:0032472 SMD11_RS23345 184756a9db7a88ad160c7eaf411c4ef8 193 Pfam PF01169 Uncharacterized protein family UPF0016 110 182 5.6E-18 T 06-07-2017 IPR001727 Gdt1 family GO:0032472 SMD11_RS13630 f149d8486c6acc984f5309a1bd79f751 532 Pfam PF01039 Carboxyl transferase domain 48 516 8.5E-132 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SMD11_RS13630 f149d8486c6acc984f5309a1bd79f751 532 Gene3D G3DSA:3.90.226.10 31 266 3.0E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS13630 f149d8486c6acc984f5309a1bd79f751 532 Gene3D G3DSA:3.90.226.10 274 521 2.8E-77 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS13630 f149d8486c6acc984f5309a1bd79f751 532 SUPERFAMILY SSF52096 23 263 3.37E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS13630 f149d8486c6acc984f5309a1bd79f751 532 SUPERFAMILY SSF52096 232 512 4.62E-75 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS28730 91e03b7bbdfa49c8f13c07919d8422e4 147 SUPERFAMILY SSF81330 10 104 6.02E-18 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMD11_RS28730 91e03b7bbdfa49c8f13c07919d8422e4 147 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 2 101 1.1E-22 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SMD11_RS18235 87357f080f24ec5c3750015ff790e05a 80 SUPERFAMILY SSF46955 24 73 2.56E-5 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS18235 87357f080f24ec5c3750015ff790e05a 80 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 24 71 6.6E-21 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 SMD11_RS18235 87357f080f24ec5c3750015ff790e05a 80 Pfam PF12728 Helix-turn-helix domain 24 72 2.0E-14 T 06-07-2017 SMD11_RS18235 87357f080f24ec5c3750015ff790e05a 80 Gene3D G3DSA:1.10.10.10 25 72 6.2E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28970 c26459dfac86ee250fc8572296288252 390 SUPERFAMILY SSF56601 37 356 6.52E-74 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS28970 c26459dfac86ee250fc8572296288252 390 Gene3D G3DSA:3.40.710.10 38 353 1.9E-75 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS28970 c26459dfac86ee250fc8572296288252 390 Pfam PF00144 Beta-lactamase 31 333 1.3E-60 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS08690 311ea921d966e745152188770448f187 226 SUPERFAMILY SSF46785 159 221 6.12E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS08690 311ea921d966e745152188770448f187 226 SMART SM00448 2 115 2.5E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS08690 311ea921d966e745152188770448f187 226 SUPERFAMILY SSF52172 1 136 4.84E-31 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS08690 311ea921d966e745152188770448f187 226 Gene3D G3DSA:3.40.50.2300 1 127 8.6E-27 T 06-07-2017 SMD11_RS08690 311ea921d966e745152188770448f187 226 PIRSF PIRSF006171 1 225 4.5E-77 T 06-07-2017 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 SMD11_RS08690 311ea921d966e745152188770448f187 226 Pfam PF09339 IclR helix-turn-helix domain 167 205 5.9E-8 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 SMD11_RS08690 311ea921d966e745152188770448f187 226 Pfam PF00072 Response regulator receiver domain 4 114 4.3E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS08690 311ea921d966e745152188770448f187 226 Gene3D G3DSA:1.10.10.10 167 205 4.2E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS11680 b6286f75af24043e3534cd7cb3c531c1 333 SUPERFAMILY SSF161098 104 294 1.31E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11680 b6286f75af24043e3534cd7cb3c531c1 333 Gene3D G3DSA:1.10.3720.10 101 309 3.7E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11680 b6286f75af24043e3534cd7cb3c531c1 333 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 21 62 1.6E-9 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD11_RS11680 b6286f75af24043e3534cd7cb3c531c1 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 310 1.6E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS19310 b199d9ccb7d3e98f49eb16b5828a957d 399 SUPERFAMILY SSF51556 5 34 8.32E-76 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS19310 b199d9ccb7d3e98f49eb16b5828a957d 399 SUPERFAMILY SSF51556 84 396 8.32E-76 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS19310 b199d9ccb7d3e98f49eb16b5828a957d 399 Gene3D G3DSA:3.20.20.140 6 33 3.1E-71 T 06-07-2017 SMD11_RS19310 b199d9ccb7d3e98f49eb16b5828a957d 399 Gene3D G3DSA:3.20.20.140 81 395 3.1E-71 T 06-07-2017 SMD11_RS19310 b199d9ccb7d3e98f49eb16b5828a957d 399 Pfam PF04909 Amidohydrolase 93 392 2.3E-46 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 SMD11_RS00780 bb53a627acb9b0516c634a321ed88cf7 195 Gene3D G3DSA:1.10.630.10 11 195 7.3E-68 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00780 bb53a627acb9b0516c634a321ed88cf7 195 SUPERFAMILY SSF48264 14 195 2.49E-56 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00780 bb53a627acb9b0516c634a321ed88cf7 195 PRINTS PR00359 B-class P450 signature 68 79 3.1E-30 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00780 bb53a627acb9b0516c634a321ed88cf7 195 PRINTS PR00359 B-class P450 signature 86 113 3.1E-30 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00780 bb53a627acb9b0516c634a321ed88cf7 195 PRINTS PR00359 B-class P450 signature 114 129 3.1E-30 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00780 bb53a627acb9b0516c634a321ed88cf7 195 PRINTS PR00359 B-class P450 signature 135 144 3.1E-30 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00780 bb53a627acb9b0516c634a321ed88cf7 195 PRINTS PR00359 B-class P450 signature 144 155 3.1E-30 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS00780 bb53a627acb9b0516c634a321ed88cf7 195 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 137 146 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS00780 bb53a627acb9b0516c634a321ed88cf7 195 PRINTS PR00385 P450 superfamily signature 33 50 4.0E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00780 bb53a627acb9b0516c634a321ed88cf7 195 PRINTS PR00385 P450 superfamily signature 68 79 4.0E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00780 bb53a627acb9b0516c634a321ed88cf7 195 PRINTS PR00385 P450 superfamily signature 135 144 4.0E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00780 bb53a627acb9b0516c634a321ed88cf7 195 PRINTS PR00385 P450 superfamily signature 144 155 4.0E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS00780 bb53a627acb9b0516c634a321ed88cf7 195 Pfam PF00067 Cytochrome P450 17 165 1.7E-22 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS18985 c3a6e018fc2196505dee048a366aa141 151 SUPERFAMILY SSF52080 10 149 2.62E-39 T 06-07-2017 IPR021131 Ribosomal protein L18e/L15P SMD11_RS18985 c3a6e018fc2196505dee048a366aa141 151 Gene3D G3DSA:3.100.10.10 37 150 7.8E-31 T 06-07-2017 SMD11_RS18985 c3a6e018fc2196505dee048a366aa141 151 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 9 150 18.381 T 06-07-2017 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 SMD11_RS18985 c3a6e018fc2196505dee048a366aa141 151 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 32 148 4.6E-32 T 06-07-2017 IPR021131 Ribosomal protein L18e/L15P SMD11_RS18985 c3a6e018fc2196505dee048a366aa141 151 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 8 147 2.0E-44 T 06-07-2017 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18985 c3a6e018fc2196505dee048a366aa141 151 ProSitePatterns PS00475 Ribosomal protein L15 signature. 114 144 - T 06-07-2017 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS24940 d3ab324353ee64517badbb833fe5365e 157 SUPERFAMILY SSF54637 26 150 4.43E-30 T 06-07-2017 IPR029069 HotDog domain SMD11_RS24940 d3ab324353ee64517badbb833fe5365e 157 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 37 146 2.3E-28 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 SMD11_RS24940 d3ab324353ee64517badbb833fe5365e 157 Gene3D G3DSA:3.10.129.10 24 149 2.4E-48 T 06-07-2017 IPR029069 HotDog domain SMD11_RS24940 d3ab324353ee64517badbb833fe5365e 157 Pfam PF03061 Thioesterase superfamily 62 139 7.8E-18 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 SMD11_RS17315 c8e14bc0e65c1059d8b8de55f6c52bea 317 Pfam PF13365 Trypsin-like peptidase domain 129 268 1.3E-6 T 06-07-2017 SMD11_RS17315 c8e14bc0e65c1059d8b8de55f6c52bea 317 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 139 144 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD11_RS17315 c8e14bc0e65c1059d8b8de55f6c52bea 317 SUPERFAMILY SSF50494 81 287 7.21E-18 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS17315 c8e14bc0e65c1059d8b8de55f6c52bea 317 Gene3D G3DSA:2.40.10.10 121 198 1.5E-10 T 06-07-2017 SMD11_RS30490 e28dcb91bebd3b967f620a949a2dbe1e 445 Pfam PF00067 Cytochrome P450 21 421 2.3E-72 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30490 e28dcb91bebd3b967f620a949a2dbe1e 445 SUPERFAMILY SSF48264 19 437 3.8E-93 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30490 e28dcb91bebd3b967f620a949a2dbe1e 445 PRINTS PR00385 P450 superfamily signature 385 396 1.9E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30490 e28dcb91bebd3b967f620a949a2dbe1e 445 PRINTS PR00385 P450 superfamily signature 248 265 1.9E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30490 e28dcb91bebd3b967f620a949a2dbe1e 445 PRINTS PR00385 P450 superfamily signature 301 312 1.9E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30490 e28dcb91bebd3b967f620a949a2dbe1e 445 PRINTS PR00385 P450 superfamily signature 376 385 1.9E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30490 e28dcb91bebd3b967f620a949a2dbe1e 445 Gene3D G3DSA:1.10.630.10 21 437 1.4E-96 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30490 e28dcb91bebd3b967f620a949a2dbe1e 445 PRINTS PR00463 E-class P450 group I signature 300 318 1.6E-25 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30490 e28dcb91bebd3b967f620a949a2dbe1e 445 PRINTS PR00463 E-class P450 group I signature 385 408 1.6E-25 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30490 e28dcb91bebd3b967f620a949a2dbe1e 445 PRINTS PR00463 E-class P450 group I signature 340 364 1.6E-25 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30490 e28dcb91bebd3b967f620a949a2dbe1e 445 PRINTS PR00463 E-class P450 group I signature 257 283 1.6E-25 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30490 e28dcb91bebd3b967f620a949a2dbe1e 445 PRINTS PR00463 E-class P450 group I signature 31 50 1.6E-25 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30490 e28dcb91bebd3b967f620a949a2dbe1e 445 PRINTS PR00463 E-class P450 group I signature 375 385 1.6E-25 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS17645 43b4e1cfff7e07f56ab2073b897b74d4 62 Pfam PF04149 Domain of unknown function (DUF397) 3 55 7.0E-14 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS34440 3f4b4b2d722408f01b62b327f2806bec 270 SUPERFAMILY SSF56112 41 204 1.08E-10 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS34440 3f4b4b2d722408f01b62b327f2806bec 270 Gene3D G3DSA:3.90.1200.10 123 223 2.0E-4 T 06-07-2017 SMD11_RS04470 0d92d3650d0b6432d81ad7724d2edb29 145 SUPERFAMILY SSF54427 1 142 5.86E-40 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS04470 0d92d3650d0b6432d81ad7724d2edb29 145 Gene3D G3DSA:3.10.450.50 5 144 1.7E-45 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS04470 0d92d3650d0b6432d81ad7724d2edb29 145 Pfam PF07366 SnoaL-like polyketide cyclase 10 139 2.1E-33 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain SMD11_RS05405 73336b3f29ff280d16857ea858962c19 211 Pfam PF03729 Short repeat of unknown function (DUF308) 25 94 3.9E-9 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane SMD11_RS05405 73336b3f29ff280d16857ea858962c19 211 Pfam PF03729 Short repeat of unknown function (DUF308) 82 149 4.9E-6 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane SMD11_RS09945 356199955f61dd2c55552d48b3a17c7d 544 SUPERFAMILY SSF51569 17 309 2.38E-76 T 06-07-2017 SMD11_RS09945 356199955f61dd2c55552d48b3a17c7d 544 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 21 538 1.3E-192 T 06-07-2017 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 SMD11_RS09945 356199955f61dd2c55552d48b3a17c7d 544 Pfam PF08502 LeuA allosteric (dimerisation) domain 392 533 3.6E-26 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD11_RS09945 356199955f61dd2c55552d48b3a17c7d 544 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 28 44 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD11_RS09945 356199955f61dd2c55552d48b3a17c7d 544 SUPERFAMILY SSF110921 417 530 7.85E-20 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD11_RS09945 356199955f61dd2c55552d48b3a17c7d 544 Pfam PF00682 HMGL-like 22 273 1.1E-46 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 SMD11_RS09945 356199955f61dd2c55552d48b3a17c7d 544 Gene3D G3DSA:3.20.20.70 16 366 2.1E-113 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS09945 356199955f61dd2c55552d48b3a17c7d 544 SMART SM00917 392 535 3.0E-37 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 SMD11_RS18225 47343b1d295b2458bd921935bc222cc1 390 PRINTS PR01270 Histone deacetylase superfamily signature 247 257 7.3E-18 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SMD11_RS18225 47343b1d295b2458bd921935bc222cc1 390 PRINTS PR01270 Histone deacetylase superfamily signature 161 176 7.3E-18 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SMD11_RS18225 47343b1d295b2458bd921935bc222cc1 390 PRINTS PR01270 Histone deacetylase superfamily signature 128 151 7.3E-18 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SMD11_RS18225 47343b1d295b2458bd921935bc222cc1 390 Gene3D G3DSA:3.40.800.20 4 350 1.6E-88 T 06-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SMD11_RS18225 47343b1d295b2458bd921935bc222cc1 390 SUPERFAMILY SSF52768 6 349 1.92E-100 T 06-07-2017 SMD11_RS18225 47343b1d295b2458bd921935bc222cc1 390 Pfam PF00850 Histone deacetylase domain 22 316 1.3E-67 T 06-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 SMD11_RS18225 47343b1d295b2458bd921935bc222cc1 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 84 98 6.2E-7 T 06-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 SMD11_RS18225 47343b1d295b2458bd921935bc222cc1 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 105 118 6.2E-7 T 06-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 SMD11_RS18225 47343b1d295b2458bd921935bc222cc1 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 16 36 6.2E-7 T 06-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 SMD11_RS31705 664da506bb082f193fc41fe82bc4e367 418 Pfam PF05147 Lanthionine synthetase C-like protein 50 416 5.7E-44 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS31705 664da506bb082f193fc41fe82bc4e367 418 SUPERFAMILY SSF158745 47 418 4.97E-63 T 06-07-2017 SMD11_RS31705 664da506bb082f193fc41fe82bc4e367 418 PRINTS PR01955 Frankia sp. LanC-like protein signature 152 168 1.9E-33 T 06-07-2017 IPR020434 LanC-like protein SMD11_RS31705 664da506bb082f193fc41fe82bc4e367 418 PRINTS PR01955 Frankia sp. LanC-like protein signature 50 65 1.9E-33 T 06-07-2017 IPR020434 LanC-like protein SMD11_RS31705 664da506bb082f193fc41fe82bc4e367 418 PRINTS PR01955 Frankia sp. LanC-like protein signature 243 263 1.9E-33 T 06-07-2017 IPR020434 LanC-like protein SMD11_RS31705 664da506bb082f193fc41fe82bc4e367 418 PRINTS PR01955 Frankia sp. LanC-like protein signature 294 317 1.9E-33 T 06-07-2017 IPR020434 LanC-like protein SMD11_RS31705 664da506bb082f193fc41fe82bc4e367 418 PRINTS PR01955 Frankia sp. LanC-like protein signature 387 404 1.9E-33 T 06-07-2017 IPR020434 LanC-like protein SMD11_RS31705 664da506bb082f193fc41fe82bc4e367 418 PRINTS PR01955 Frankia sp. LanC-like protein signature 219 243 1.9E-33 T 06-07-2017 IPR020434 LanC-like protein SMD11_RS31705 664da506bb082f193fc41fe82bc4e367 418 PRINTS PR01950 LanC-like protein superfamily signature 294 314 1.1E-18 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS31705 664da506bb082f193fc41fe82bc4e367 418 PRINTS PR01950 LanC-like protein superfamily signature 153 168 1.1E-18 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS31705 664da506bb082f193fc41fe82bc4e367 418 PRINTS PR01950 LanC-like protein superfamily signature 340 353 1.1E-18 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS31705 664da506bb082f193fc41fe82bc4e367 418 PRINTS PR01950 LanC-like protein superfamily signature 386 403 1.1E-18 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS31705 664da506bb082f193fc41fe82bc4e367 418 PRINTS PR01950 LanC-like protein superfamily signature 222 238 1.1E-18 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS31705 664da506bb082f193fc41fe82bc4e367 418 PRINTS PR01950 LanC-like protein superfamily signature 99 117 1.1E-18 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS31705 664da506bb082f193fc41fe82bc4e367 418 SMART SM01260 46 416 1.5E-52 T 06-07-2017 IPR007822 Lanthionine synthetase C-like SMD11_RS02940 1622659a5e3c91b1a545f068e16c4fb2 224 Gene3D G3DSA:3.40.50.2020 97 203 8.4E-39 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS02940 1622659a5e3c91b1a545f068e16c4fb2 224 Gene3D G3DSA:3.40.50.2020 2 65 8.4E-39 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS02940 1622659a5e3c91b1a545f068e16c4fb2 224 Pfam PF00156 Phosphoribosyl transferase domain 12 191 2.8E-23 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 SMD11_RS02940 1622659a5e3c91b1a545f068e16c4fb2 224 SUPERFAMILY SSF53271 1 207 6.95E-52 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like SMD11_RS30370 734e37bc1b1d4fffb3feedc4893fdd2f 324 Pfam PF00248 Aldo/keto reductase family 16 307 4.1E-72 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS30370 734e37bc1b1d4fffb3feedc4893fdd2f 324 SUPERFAMILY SSF51430 1 308 1.96E-99 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS30370 734e37bc1b1d4fffb3feedc4893fdd2f 324 Gene3D G3DSA:3.20.20.100 1 314 1.1E-108 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS24305 97dee288dc0d400a33c132b5313677a2 433 SUPERFAMILY SSF52540 2 287 5.98E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24305 97dee288dc0d400a33c132b5313677a2 433 Pfam PF02374 Anion-transporting ATPase 2 313 2.5E-30 T 06-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 SMD11_RS24305 97dee288dc0d400a33c132b5313677a2 433 Gene3D G3DSA:3.40.50.300 4 169 7.2E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24305 97dee288dc0d400a33c132b5313677a2 433 Gene3D G3DSA:3.40.50.300 202 305 7.2E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19130 0e10044c7b113537a9a9774d93bfb7cd 208 SMART SM00530 137 192 7.5E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS19130 0e10044c7b113537a9a9774d93bfb7cd 208 Gene3D G3DSA:1.10.260.40 126 187 1.7E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS19130 0e10044c7b113537a9a9774d93bfb7cd 208 SUPERFAMILY SSF47413 125 187 2.82E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS19130 0e10044c7b113537a9a9774d93bfb7cd 208 Pfam PF13560 Helix-turn-helix domain 134 187 2.9E-12 T 06-07-2017 SMD11_RS14375 49944ed4340edca15031cc6b84907f88 321 Gene3D G3DSA:3.40.50.1820 225 291 3.7E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS14375 49944ed4340edca15031cc6b84907f88 321 Gene3D G3DSA:3.40.50.1820 27 158 3.7E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS14375 49944ed4340edca15031cc6b84907f88 321 Pfam PF00561 alpha/beta hydrolase fold 52 142 6.6E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS14375 49944ed4340edca15031cc6b84907f88 321 SUPERFAMILY SSF53474 30 297 3.11E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04695 78df9d71e2f724036f742f428f2782c8 651 Pfam PF00733 Asparagine synthase 352 603 8.7E-5 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 SMD11_RS04695 78df9d71e2f724036f742f428f2782c8 651 Gene3D G3DSA:3.60.20.10 121 207 2.7E-6 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS30295 7e3198520ed823e950c348bfc77449b2 412 SMART SM00331 187 407 2.7E-23 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS30295 7e3198520ed823e950c348bfc77449b2 412 SUPERFAMILY SSF55781 47 162 7.36E-6 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS30295 7e3198520ed823e950c348bfc77449b2 412 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 216 407 6.2E-41 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS30295 7e3198520ed823e950c348bfc77449b2 412 SUPERFAMILY SSF81606 203 404 1.03E-10 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS30295 7e3198520ed823e950c348bfc77449b2 412 Gene3D G3DSA:3.60.40.10 251 405 1.9E-4 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS06520 a70d6cdcd53410c453de7afdafae19a4 279 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 86 107 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD11_RS06520 a70d6cdcd53410c453de7afdafae19a4 279 Pfam PF01066 CDP-alcohol phosphatidyltransferase 28 107 3.8E-12 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD11_RS06520 a70d6cdcd53410c453de7afdafae19a4 279 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 33 205 2.2E-33 T 06-07-2017 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 SMD11_RS27380 822c61ecc27347f9c886cdc256f8eef0 107 Gene3D G3DSA:1.10.8.50 50 103 1.0E-13 T 06-07-2017 SMD11_RS27380 822c61ecc27347f9c886cdc256f8eef0 107 SUPERFAMILY SSF46946 57 102 1.88E-7 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SMD11_RS29575 fb7138c040f99a71a9c9e530772b253f 184 SUPERFAMILY SSF55729 9 172 8.99E-35 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS29575 fb7138c040f99a71a9c9e530772b253f 184 Gene3D G3DSA:3.40.630.30 10 172 3.6E-40 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS29575 fb7138c040f99a71a9c9e530772b253f 184 Pfam PF13302 Acetyltransferase (GNAT) domain 11 147 7.0E-22 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS21885 edba3d44532d9c0e3e722b847db0e9fa 68 SUPERFAMILY SSF46955 6 57 2.88E-9 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS21885 edba3d44532d9c0e3e722b847db0e9fa 68 Gene3D G3DSA:1.10.1660.10 5 44 1.1E-5 T 06-07-2017 SMD11_RS21885 edba3d44532d9c0e3e722b847db0e9fa 68 Pfam PF13411 MerR HTH family regulatory protein 9 44 8.3E-5 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS08870 f22618aefe0facce2e1b8b1036f9d65b 312 SUPERFAMILY SSF52540 10 152 7.79E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08870 f22618aefe0facce2e1b8b1036f9d65b 312 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 289 9.5E-77 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 SMD11_RS08870 f22618aefe0facce2e1b8b1036f9d65b 312 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 10 311 28.258 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 SMD11_RS08870 f22618aefe0facce2e1b8b1036f9d65b 312 Pfam PF01715 IPP transferase 43 285 2.1E-75 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 SMD11_RS08870 f22618aefe0facce2e1b8b1036f9d65b 312 Gene3D G3DSA:1.10.287.890 201 282 3.2E-25 T 06-07-2017 SMD11_RS08870 f22618aefe0facce2e1b8b1036f9d65b 312 Gene3D G3DSA:3.40.50.300 8 175 6.4E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS30135 d6a457a5a0caf6959c2e90707224baac 146 Pfam PF00583 Acetyltransferase (GNAT) family 52 128 1.2E-9 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS30135 d6a457a5a0caf6959c2e90707224baac 146 SUPERFAMILY SSF55729 3 133 1.1E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS30135 d6a457a5a0caf6959c2e90707224baac 146 Gene3D G3DSA:3.40.630.30 3 142 2.0E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS26900 dba031be7f6f364e6ad4e4eae00ad9d9 285 Pfam PF00196 Bacterial regulatory proteins, luxR family 219 267 5.1E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS26900 dba031be7f6f364e6ad4e4eae00ad9d9 285 SUPERFAMILY SSF46894 219 278 4.42E-8 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS26900 dba031be7f6f364e6ad4e4eae00ad9d9 285 SMART SM00421 214 271 3.9E-4 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS26900 dba031be7f6f364e6ad4e4eae00ad9d9 285 SUPERFAMILY SSF56024 27 178 1.62E-6 T 06-07-2017 SMD11_RS26900 dba031be7f6f364e6ad4e4eae00ad9d9 285 Gene3D G3DSA:3.30.870.10 32 130 1.1E-4 T 06-07-2017 SMD11_RS26900 dba031be7f6f364e6ad4e4eae00ad9d9 285 Gene3D G3DSA:1.10.10.10 220 278 4.0E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30580 7818f64cb9f800e0b45d93d332314836 214 Gene3D G3DSA:1.10.357.10 58 190 3.1E-19 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS30580 7818f64cb9f800e0b45d93d332314836 214 Gene3D G3DSA:1.10.10.60 4 57 7.4E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS30580 7818f64cb9f800e0b45d93d332314836 214 SUPERFAMILY SSF48498 82 193 9.74E-16 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS30580 7818f64cb9f800e0b45d93d332314836 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 61 1.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS30580 7818f64cb9f800e0b45d93d332314836 214 SUPERFAMILY SSF46689 4 81 4.0E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS23260 95493919962feac2ee12fa9fb92676e5 135 Pfam PF03995 Peptidase inhibitor family I36 45 108 5.2E-11 T 06-07-2017 SMD11_RS31070 d89da6e5ac60b46c8863e486d3035ffd 180 Gene3D G3DSA:3.90.960.10 33 172 1.8E-29 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD11_RS31070 d89da6e5ac60b46c8863e486d3035ffd 180 Pfam PF04073 Aminoacyl-tRNA editing domain 42 159 4.1E-20 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD11_RS31070 d89da6e5ac60b46c8863e486d3035ffd 180 SUPERFAMILY SSF55826 34 172 2.09E-26 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SMD11_RS19920 40784ff80604c9c866648629ad14f2ea 265 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 3 263 1.0E-74 T 06-07-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 SMD11_RS19920 40784ff80604c9c866648629ad14f2ea 265 Gene3D G3DSA:3.60.10.10 1 264 1.8E-90 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS19920 40784ff80604c9c866648629ad14f2ea 265 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 256 1.7E-28 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS19920 40784ff80604c9c866648629ad14f2ea 265 SUPERFAMILY SSF56219 2 265 8.64E-74 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS19920 40784ff80604c9c866648629ad14f2ea 265 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 4 262 1.4E-71 T 06-07-2017 SMD11_RS12800 26f06cf5aa5bce1f7621b0933103c3a7 400 Pfam PF00144 Beta-lactamase 63 390 2.2E-60 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS12800 26f06cf5aa5bce1f7621b0933103c3a7 400 SUPERFAMILY SSF56601 53 380 2.75E-73 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS12800 26f06cf5aa5bce1f7621b0933103c3a7 400 Gene3D G3DSA:3.40.710.10 62 384 4.4E-77 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS32085 b30566566e89eb439b9bfdd24626dcac 302 Gene3D G3DSA:1.10.600.10 17 299 1.3E-22 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS32085 b30566566e89eb439b9bfdd24626dcac 302 Pfam PF00494 Squalene/phytoene synthase 37 279 7.6E-26 T 06-07-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 SMD11_RS32085 b30566566e89eb439b9bfdd24626dcac 302 SUPERFAMILY SSF48576 21 300 1.31E-25 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS28610 60bd5bef35a0cb5e3523831e90e487ae 382 SUPERFAMILY SSF141523 230 350 2.35E-22 T 06-07-2017 SMD11_RS28610 60bd5bef35a0cb5e3523831e90e487ae 382 Gene3D G3DSA:2.40.440.10 230 351 5.9E-17 T 06-07-2017 SMD11_RS28610 60bd5bef35a0cb5e3523831e90e487ae 382 Pfam PF03734 L,D-transpeptidase catalytic domain 234 350 3.8E-14 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMD11_RS08245 58f31a3f2bba64817681f39bd05d336a 304 SUPERFAMILY SSF52151 195 284 1.12E-30 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08245 58f31a3f2bba64817681f39bd05d336a 304 SUPERFAMILY SSF52151 3 124 1.12E-30 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SMD11_RS08245 58f31a3f2bba64817681f39bd05d336a 304 Gene3D G3DSA:3.40.366.10 2 118 3.2E-25 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS08245 58f31a3f2bba64817681f39bd05d336a 304 Gene3D G3DSA:3.40.366.10 193 279 3.2E-25 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SMD11_RS21675 fa6df7fcd7e2bf37c5d3f37f0e9aa12f 442 Gene3D G3DSA:3.40.190.10 62 173 2.0E-8 T 06-07-2017 SMD11_RS21675 fa6df7fcd7e2bf37c5d3f37f0e9aa12f 442 SUPERFAMILY SSF53850 48 440 1.14E-44 T 06-07-2017 SMD11_RS21675 fa6df7fcd7e2bf37c5d3f37f0e9aa12f 442 Gene3D G3DSA:3.40.190.10 174 366 7.0E-24 T 06-07-2017 SMD11_RS21675 fa6df7fcd7e2bf37c5d3f37f0e9aa12f 442 Pfam PF13416 Bacterial extracellular solute-binding protein 65 372 4.6E-22 T 06-07-2017 SMD11_RS01445 9a53f331dea0efd921d6e0a50442d471 408 PRINTS PR00359 B-class P450 signature 281 292 7.2E-22 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01445 9a53f331dea0efd921d6e0a50442d471 408 PRINTS PR00359 B-class P450 signature 299 326 7.2E-22 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01445 9a53f331dea0efd921d6e0a50442d471 408 PRINTS PR00359 B-class P450 signature 348 357 7.2E-22 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01445 9a53f331dea0efd921d6e0a50442d471 408 PRINTS PR00359 B-class P450 signature 162 177 7.2E-22 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01445 9a53f331dea0efd921d6e0a50442d471 408 PRINTS PR00359 B-class P450 signature 327 342 7.2E-22 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01445 9a53f331dea0efd921d6e0a50442d471 408 PRINTS PR00359 B-class P450 signature 357 368 7.2E-22 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS01445 9a53f331dea0efd921d6e0a50442d471 408 SUPERFAMILY SSF48264 27 408 8.91E-70 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS01445 9a53f331dea0efd921d6e0a50442d471 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 350 359 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS01445 9a53f331dea0efd921d6e0a50442d471 408 Pfam PF00067 Cytochrome P450 280 377 1.8E-15 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS01445 9a53f331dea0efd921d6e0a50442d471 408 Gene3D G3DSA:1.10.630.10 25 408 2.3E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30285 fa665415915942ec37fef0460dc971be 401 Gene3D G3DSA:3.30.470.20 107 310 1.8E-17 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS30285 fa665415915942ec37fef0460dc971be 401 SUPERFAMILY SSF56059 93 308 2.98E-27 T 06-07-2017 SMD11_RS04520 7a2ce179e57a32a2e0b6e53c97d337fd 411 Gene3D G3DSA:3.40.50.1820 176 407 5.2E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04520 7a2ce179e57a32a2e0b6e53c97d337fd 411 Pfam PF00756 Putative esterase 193 404 3.6E-30 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 SMD11_RS04520 7a2ce179e57a32a2e0b6e53c97d337fd 411 Gene3D G3DSA:2.60.40.10 18 151 6.7E-30 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS04520 7a2ce179e57a32a2e0b6e53c97d337fd 411 Pfam PF11806 Domain of unknown function (DUF3327) 52 173 3.7E-28 T 06-07-2017 IPR021764 Enterochelin esterase, N-terminal GO:0005506|GO:0005737|GO:0006826|GO:0008849 SMD11_RS04520 7a2ce179e57a32a2e0b6e53c97d337fd 411 SUPERFAMILY SSF53474 192 404 3.7E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS04520 7a2ce179e57a32a2e0b6e53c97d337fd 411 SUPERFAMILY SSF81296 21 169 2.24E-28 T 06-07-2017 IPR014756 Immunoglobulin E-set SMD11_RS00170 88650cecf28bbeb6bd0e3d2423ed2f68 214 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 184 67.695 T 06-07-2017 IPR020765 Uncharacterised protein family UPF0114, gammaproteobacteria GO:0005886 SMD11_RS00170 88650cecf28bbeb6bd0e3d2423ed2f68 214 Pfam PF03350 Uncharacterized protein family, UPF0114 25 143 8.3E-38 T 06-07-2017 IPR005134 Uncharacterised protein family UPF0114 SMD11_RS00170 88650cecf28bbeb6bd0e3d2423ed2f68 214 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 24 174 2.1E-52 T 06-07-2017 IPR020761 Uncharacterised protein family UPF0114, bacteria SMD11_RS30340 c51cb7a76ebb24eedb778c96c39ad229 329 Pfam PF04055 Radical SAM superfamily 53 223 6.5E-7 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS30340 c51cb7a76ebb24eedb778c96c39ad229 329 SUPERFAMILY SSF102114 46 259 2.94E-7 T 06-07-2017 SMD11_RS30495 76afd532dbf71978699c8fdb01c55b5a 340 SUPERFAMILY SSF56219 41 206 1.68E-21 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS30495 76afd532dbf71978699c8fdb01c55b5a 340 SUPERFAMILY SSF56219 234 335 1.68E-21 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS30495 76afd532dbf71978699c8fdb01c55b5a 340 SUPERFAMILY SSF56219 6 14 1.68E-21 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS30495 76afd532dbf71978699c8fdb01c55b5a 340 Gene3D G3DSA:3.60.10.10 9 336 9.6E-10 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS30495 76afd532dbf71978699c8fdb01c55b5a 340 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 9 218 1.4E-6 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase SMD11_RS03270 730bdd355f0a15ec847ff119329d07ec 182 SUPERFAMILY SSF55729 12 161 3.09E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS03270 730bdd355f0a15ec847ff119329d07ec 182 Gene3D G3DSA:3.40.630.30 11 162 1.9E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS03270 730bdd355f0a15ec847ff119329d07ec 182 Pfam PF13673 Acetyltransferase (GNAT) domain 63 154 2.1E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS11825 048b465ddd27e5f0682001de63985140 264 Pfam PF13490 Putative zinc-finger 16 41 1.2E-5 T 06-07-2017 IPR027383 Putative zinc-finger SMD11_RS10040 941ab5c28a97aece8ec5a6eb421c2142 329 Pfam PF00296 Luciferase-like monooxygenase 18 297 2.1E-30 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS10040 941ab5c28a97aece8ec5a6eb421c2142 329 SUPERFAMILY SSF51679 5 321 1.07E-63 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS10040 941ab5c28a97aece8ec5a6eb421c2142 329 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 6 320 1.7E-99 T 06-07-2017 IPR019949 Luciferase family oxidoreductase, group 1 SMD11_RS10040 941ab5c28a97aece8ec5a6eb421c2142 329 Gene3D G3DSA:3.20.20.30 4 322 5.9E-70 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS09900 173677b47847e60f3bde871ab5a11712 140 SMART SM00960 12 102 7.5E-33 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS09900 173677b47847e60f3bde871ab5a11712 140 Pfam PF03259 Roadblock/LC7 domain 12 102 1.4E-25 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS09900 173677b47847e60f3bde871ab5a11712 140 Gene3D G3DSA:3.30.450.30 6 126 1.6E-25 T 06-07-2017 SMD11_RS09900 173677b47847e60f3bde871ab5a11712 140 SUPERFAMILY SSF103196 4 128 6.98E-32 T 06-07-2017 SMD11_RS28710 7188851a413132e0527936912fb0c015 426 Pfam PF07730 Histidine kinase 210 273 5.2E-13 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS28710 7188851a413132e0527936912fb0c015 426 SUPERFAMILY SSF55874 298 405 9.25E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS20555 20f02585031826aaf53f7dfc73931a72 389 Gene3D G3DSA:2.60.40.230 54 112 9.2E-5 T 06-07-2017 IPR027273 Neocarzinostatin-like SMD11_RS20555 20f02585031826aaf53f7dfc73931a72 389 SUPERFAMILY SSF49319 53 133 2.09E-5 T 06-07-2017 IPR027273 Neocarzinostatin-like SMD11_RS21940 ce7df1de775dcf485a94f547e90eb827 119 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 115 18.88 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMD11_RS21940 ce7df1de775dcf485a94f547e90eb827 119 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 110 2.1E-24 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMD11_RS21940 ce7df1de775dcf485a94f547e90eb827 119 TIGRFAM TIGR00494 crcB: protein CrcB 5 113 3.8E-26 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMD11_RS05750 03ec3cffb4b5e521edde34156f24c16f 521 Gene3D G3DSA:3.40.605.10 40 277 5.5E-42 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS05750 03ec3cffb4b5e521edde34156f24c16f 521 Gene3D G3DSA:3.40.309.10 278 464 6.1E-34 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS05750 03ec3cffb4b5e521edde34156f24c16f 521 SUPERFAMILY SSF53720 39 500 1.7E-79 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS05750 03ec3cffb4b5e521edde34156f24c16f 521 Pfam PF00171 Aldehyde dehydrogenase family 53 496 3.4E-96 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS00965 ad46cde325b448e13c98081fbb11fbe8 474 Gene3D G3DSA:3.30.200.20 12 145 7.3E-15 T 06-07-2017 SMD11_RS00965 ad46cde325b448e13c98081fbb11fbe8 474 SMART SM00220 18 308 1.3E-29 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS00965 ad46cde325b448e13c98081fbb11fbe8 474 Gene3D G3DSA:1.10.510.10 146 301 1.3E-30 T 06-07-2017 SMD11_RS00965 ad46cde325b448e13c98081fbb11fbe8 474 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 24 57 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS00965 ad46cde325b448e13c98081fbb11fbe8 474 Pfam PF00069 Protein kinase domain 19 249 2.2E-33 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS00965 ad46cde325b448e13c98081fbb11fbe8 474 SUPERFAMILY SSF56112 13 300 3.63E-49 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS32040 67a2837354ae6717588b321953f047f5 151 SUPERFAMILY SSF51206 7 142 9.69E-21 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like SMD11_RS32040 67a2837354ae6717588b321953f047f5 151 Gene3D G3DSA:2.60.120.10 6 142 1.3E-14 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS32040 67a2837354ae6717588b321953f047f5 151 Pfam PF00027 Cyclic nucleotide-binding domain 26 113 9.0E-10 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain SMD11_RS11180 ebef4f918a2562e1b59a137ff731385c 76 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 6 49 5.3E-16 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 SMD11_RS11180 ebef4f918a2562e1b59a137ff731385c 76 Pfam PF02416 mttA/Hcf106 family 8 52 7.3E-16 T 06-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 SMD11_RS11180 ebef4f918a2562e1b59a137ff731385c 76 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 3 76 17.428 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 SMD11_RS25980 d88a55ad11e0cd2f50c22a240fc57413 348 Pfam PF00296 Luciferase-like monooxygenase 25 281 2.8E-33 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS25980 d88a55ad11e0cd2f50c22a240fc57413 348 Gene3D G3DSA:3.20.20.30 11 336 8.8E-84 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS25980 d88a55ad11e0cd2f50c22a240fc57413 348 SUPERFAMILY SSF51679 23 335 5.74E-68 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS05600 9e85760e10bf1e88f07c132e306f2fd8 234 SUPERFAMILY SSF48498 106 215 4.08E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS05600 9e85760e10bf1e88f07c132e306f2fd8 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 43 89 5.1E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS05600 9e85760e10bf1e88f07c132e306f2fd8 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 64 87 1.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS05600 9e85760e10bf1e88f07c132e306f2fd8 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 56 1.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS05600 9e85760e10bf1e88f07c132e306f2fd8 234 SUPERFAMILY SSF46689 31 99 1.13E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS05600 9e85760e10bf1e88f07c132e306f2fd8 234 Gene3D G3DSA:1.10.357.10 27 216 5.1E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS32675 f8fb2985e49419ff1322195d6fa67a32 278 Gene3D G3DSA:3.40.50.1820 32 266 4.8E-14 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32675 f8fb2985e49419ff1322195d6fa67a32 278 SUPERFAMILY SSF53474 32 222 4.91E-12 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32675 f8fb2985e49419ff1322195d6fa67a32 278 Pfam PF01738 Dienelactone hydrolase family 34 159 1.9E-7 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 SMD11_RS18745 a0bf7b461ef4475311b399e007602a44 162 Gene3D G3DSA:3.30.70.860 97 162 9.7E-29 T 06-07-2017 SMD11_RS18745 a0bf7b461ef4475311b399e007602a44 162 Gene3D G3DSA:3.30.70.990 11 96 7.5E-31 T 06-07-2017 SMD11_RS18745 a0bf7b461ef4475311b399e007602a44 162 Pfam PF04461 Protein of unknown function (DUF520) 4 162 1.3E-60 T 06-07-2017 IPR007551 Protein of unknown function DUF520 SMD11_RS18745 a0bf7b461ef4475311b399e007602a44 162 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 162 25.769 T 06-07-2017 IPR007551 Protein of unknown function DUF520 SMD11_RS18745 a0bf7b461ef4475311b399e007602a44 162 SUPERFAMILY SSF89963 90 162 6.02E-23 T 06-07-2017 IPR007551 Protein of unknown function DUF520 SMD11_RS18745 a0bf7b461ef4475311b399e007602a44 162 SUPERFAMILY SSF89963 5 88 1.57E-28 T 06-07-2017 IPR007551 Protein of unknown function DUF520 SMD11_RS03260 95f43a34c9ffc6b3335e8017b54e06b8 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 127 296 2.3E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS03260 95f43a34c9ffc6b3335e8017b54e06b8 305 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 88 191 4.6E-17 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SMD11_RS03260 95f43a34c9ffc6b3335e8017b54e06b8 305 Gene3D G3DSA:1.10.3720.10 88 297 2.4E-39 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS03260 95f43a34c9ffc6b3335e8017b54e06b8 305 SUPERFAMILY SSF161098 90 282 8.76E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS28380 e5a0532290da166fdab85f7ce11aba24 717 SUPERFAMILY SSF55781 183 323 3.05E-15 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS28380 e5a0532290da166fdab85f7ce11aba24 717 Gene3D G3DSA:3.60.40.10 480 552 1.1E-4 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS28380 e5a0532290da166fdab85f7ce11aba24 717 Pfam PF13185 GAF domain 183 311 9.9E-9 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS28380 e5a0532290da166fdab85f7ce11aba24 717 SUPERFAMILY SSF55874 596 684 3.44E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS28380 e5a0532290da166fdab85f7ce11aba24 717 Gene3D G3DSA:3.30.565.10 593 686 2.5E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS28380 e5a0532290da166fdab85f7ce11aba24 717 SMART SM00065 154 320 0.0039 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS28380 e5a0532290da166fdab85f7ce11aba24 717 Pfam PF08447 PAS fold 45 133 2.8E-11 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 SMD11_RS28380 e5a0532290da166fdab85f7ce11aba24 717 SMART SM00331 338 554 3.2E-37 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS28380 e5a0532290da166fdab85f7ce11aba24 717 SUPERFAMILY SSF81606 352 554 6.67E-12 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS28380 e5a0532290da166fdab85f7ce11aba24 717 Pfam PF13581 Histidine kinase-like ATPase domain 571 681 3.1E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS28380 e5a0532290da166fdab85f7ce11aba24 717 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 367 554 4.1E-48 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS28380 e5a0532290da166fdab85f7ce11aba24 717 Gene3D G3DSA:3.30.450.40 159 324 6.2E-13 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS28380 e5a0532290da166fdab85f7ce11aba24 717 SUPERFAMILY SSF55785 33 137 1.45E-10 T 06-07-2017 IPR000014 PAS domain SMD11_RS28380 e5a0532290da166fdab85f7ce11aba24 717 Gene3D G3DSA:3.30.450.20 32 136 6.4E-12 T 06-07-2017 SMD11_RS22830 416e56e87265825d988eec6296be63be 283 SMART SM00530 17 72 7.2E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS22830 416e56e87265825d988eec6296be63be 283 Gene3D G3DSA:1.10.260.40 5 73 3.4E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS22830 416e56e87265825d988eec6296be63be 283 Pfam PF13560 Helix-turn-helix domain 13 70 4.0E-10 T 06-07-2017 SMD11_RS22830 416e56e87265825d988eec6296be63be 283 SUPERFAMILY SSF47413 9 68 4.5E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS07495 ab1dbb69fab2cbc0e1d8f18e244e6a24 160 PRINTS PR01759 Capsule biosynthesis protein CapC signature 71 85 2.5E-5 T 06-07-2017 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 SMD11_RS07495 ab1dbb69fab2cbc0e1d8f18e244e6a24 160 PRINTS PR01759 Capsule biosynthesis protein CapC signature 25 42 2.5E-5 T 06-07-2017 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 SMD11_RS07495 ab1dbb69fab2cbc0e1d8f18e244e6a24 160 Pfam PF14102 Capsule biosynthesis CapC 17 133 1.7E-33 T 06-07-2017 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 SMD11_RS27760 4352073a94942dd66277800c5cc11b75 161 SUPERFAMILY SSF110087 16 154 4.18E-28 T 06-07-2017 IPR007410 DR1885-like metal-binding protein SMD11_RS27760 4352073a94942dd66277800c5cc11b75 161 Pfam PF04314 Protein of unknown function (DUF461) 47 145 5.9E-22 T 06-07-2017 IPR007410 DR1885-like metal-binding protein SMD11_RS05525 325fd6a8d7ac6d3443917f795bceb19c 489 Pfam PF07730 Histidine kinase 210 273 7.4E-10 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS05525 325fd6a8d7ac6d3443917f795bceb19c 489 Gene3D G3DSA:3.30.565.10 302 404 9.8E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS05525 325fd6a8d7ac6d3443917f795bceb19c 489 SUPERFAMILY SSF55874 300 405 6.63E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS31075 a3ec0d8582861c12f7aabb0f8d8f8111 467 PIRSF PIRSF006060 10 462 3.6E-61 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS31075 a3ec0d8582861c12f7aabb0f8d8f8111 467 ProSitePatterns PS00218 Amino acid permeases signature. 55 85 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD11_RS31075 a3ec0d8582861c12f7aabb0f8d8f8111 467 Pfam PF00324 Amino acid permease 30 440 2.0E-98 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMD11_RS16950 5e0064eb194e3f0fc4af1090a30cc15b 212 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 92 210 9.2E-41 T 06-07-2017 IPR021949 Domain of unknown function DUF3566. transmembrane SMD11_RS25940 7a76b6477dc332411f43fa72a3ef8347 71 Pfam PF11720 Peptidase inhibitor I78 family 28 62 3.0E-8 T 06-07-2017 IPR021719 Proteinase inhibitor I78 SMD11_RS24805 a8cc8cb831a7495efd325d6f99c21f57 420 Pfam PF13641 Glycosyltransferase like family 2 46 283 5.2E-30 T 06-07-2017 SMD11_RS24805 a8cc8cb831a7495efd325d6f99c21f57 420 SUPERFAMILY SSF53448 41 316 8.53E-30 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS24805 a8cc8cb831a7495efd325d6f99c21f57 420 Gene3D G3DSA:3.90.550.10 49 287 2.6E-18 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS09580 90d4c0a07117dbd6f6277ca82e4fd90a 274 Gene3D G3DSA:2.10.109.10 196 250 4.0E-38 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain SMD11_RS09580 90d4c0a07117dbd6f6277ca82e4fd90a 274 Gene3D G3DSA:2.10.109.10 65 158 4.0E-38 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain SMD11_RS09580 90d4c0a07117dbd6f6277ca82e4fd90a 274 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 54 242 2.3E-37 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09580 90d4c0a07117dbd6f6277ca82e4fd90a 274 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 148 160 3.4E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09580 90d4c0a07117dbd6f6277ca82e4fd90a 274 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 68 84 3.4E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09580 90d4c0a07117dbd6f6277ca82e4fd90a 274 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 196 215 3.4E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SMD11_RS09580 90d4c0a07117dbd6f6277ca82e4fd90a 274 ProSitePatterns PS00761 Signal peptidases I signature 3. 201 214 - T 06-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 SMD11_RS09580 90d4c0a07117dbd6f6277ca82e4fd90a 274 Pfam PF00717 Peptidase S24-like 75 114 6.2E-10 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B SMD11_RS09580 90d4c0a07117dbd6f6277ca82e4fd90a 274 Pfam PF10502 Signal peptidase, peptidase S26 145 235 1.8E-5 T 06-07-2017 IPR019533 Peptidase S26 SMD11_RS09580 90d4c0a07117dbd6f6277ca82e4fd90a 274 SUPERFAMILY SSF51306 68 115 2.51E-46 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C SMD11_RS09580 90d4c0a07117dbd6f6277ca82e4fd90a 274 SUPERFAMILY SSF51306 143 248 2.51E-46 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C SMD11_RS13695 c36dee35c994723a32061af1572e2d32 281 SUPERFAMILY SSF56112 50 220 5.78E-6 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS18595 d823c060f7ac86f927429a74266fa24f 537 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 148 167 1.4E-27 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18595 d823c060f7ac86f927429a74266fa24f 537 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 270 294 1.4E-27 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18595 d823c060f7ac86f927429a74266fa24f 537 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 358 377 1.4E-27 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18595 d823c060f7ac86f927429a74266fa24f 537 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 410 436 1.4E-27 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18595 d823c060f7ac86f927429a74266fa24f 537 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 189 213 1.4E-27 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18595 d823c060f7ac86f927429a74266fa24f 537 Pfam PF00361 Proton-conducting membrane transporter 142 452 2.0E-63 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18595 d823c060f7ac86f927429a74266fa24f 537 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 519 5.9E-174 T 06-07-2017 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS24550 9d3fbd5ad2b021cc93b04eabe6a9bc91 94 Pfam PF02325 YGGT family 10 90 1.6E-12 T 06-07-2017 IPR003425 CCB3/YggT GO:0016020 SMD11_RS22090 49b3e051ee6453978f468dc9e5ee8148 131 Pfam PF06236 Tyrosinase co-factor MelC1 16 128 3.6E-35 T 06-07-2017 IPR010928 Tyrosinase co-factor MelC1 GO:0005507|GO:0042438 SMD11_RS02035 7e095cb488b11352726d33290de29247 692 Pfam PF13245 Part of AAA domain 260 294 6.4E-8 T 06-07-2017 SMD11_RS02035 7e095cb488b11352726d33290de29247 692 SUPERFAMILY SSF52540 233 691 4.09E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02035 7e095cb488b11352726d33290de29247 692 Pfam PF08378 Nuclease-related domain 39 143 2.1E-11 T 06-07-2017 IPR011528 Nuclease-related domain, NERD SMD11_RS02035 7e095cb488b11352726d33290de29247 692 Gene3D G3DSA:3.40.50.300 428 515 1.3E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02035 7e095cb488b11352726d33290de29247 692 Gene3D G3DSA:3.40.50.300 236 341 1.3E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02035 7e095cb488b11352726d33290de29247 692 Pfam PF00580 UvrD/REP helicase N-terminal domain 404 499 1.1E-9 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 SMD11_RS02035 7e095cb488b11352726d33290de29247 692 Gene3D G3DSA:3.40.50.300 516 688 7.8E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02035 7e095cb488b11352726d33290de29247 692 Pfam PF13538 UvrD-like helicase C-terminal domain 629 686 6.1E-7 T 06-07-2017 IPR027785 UvrD-like helicase C-terminal domain SMD11_RS03865 7f510fff271053f9f07b3f68bfb9a00b 168 SUPERFAMILY SSF46785 17 158 5.46E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03865 7f510fff271053f9f07b3f68bfb9a00b 168 Pfam PF12802 MarR family 50 108 3.3E-14 T 06-07-2017 SMD11_RS03865 7f510fff271053f9f07b3f68bfb9a00b 168 SMART SM00347 44 145 7.7E-22 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS03865 7f510fff271053f9f07b3f68bfb9a00b 168 Gene3D G3DSA:1.10.10.10 12 160 8.1E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03865 7f510fff271053f9f07b3f68bfb9a00b 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 101 3.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS03865 7f510fff271053f9f07b3f68bfb9a00b 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 121 3.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS03865 7f510fff271053f9f07b3f68bfb9a00b 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 135 155 3.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS03865 7f510fff271053f9f07b3f68bfb9a00b 168 ProSitePatterns PS01117 MarR-type HTH domain signature. 84 118 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site SMD11_RS25110 4046d8f538732205024027b20832186a 335 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 29.573 T 06-07-2017 IPR003802 Sporulation regulator WhiA GO:0043937 SMD11_RS25110 4046d8f538732205024027b20832186a 335 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 104 3.6E-25 T 06-07-2017 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain SMD11_RS25110 4046d8f538732205024027b20832186a 335 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 6.8E-24 T 06-07-2017 SMD11_RS25110 4046d8f538732205024027b20832186a 335 Pfam PF02650 WhiA C-terminal HTH domain 221 303 1.7E-19 T 06-07-2017 IPR023054 Sporulation regulator WhiA, C-terminal SMD11_RS25110 4046d8f538732205024027b20832186a 335 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 3.9E-111 T 06-07-2017 SMD11_RS23300 e08e1c8cd22700b92327d6663350c354 304 Pfam PF02342 TerD domain 1 177 3.6E-45 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS23300 e08e1c8cd22700b92327d6663350c354 304 Gene3D G3DSA:2.60.60.30 16 174 2.2E-30 T 06-07-2017 SMD11_RS18600 5d3fd91aaed63ae801504ebfd76effa8 550 Pfam PF00361 Proton-conducting membrane transporter 180 484 1.9E-70 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18600 5d3fd91aaed63ae801504ebfd76effa8 550 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 155 538 2.6E-116 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 SMD11_RS18600 5d3fd91aaed63ae801504ebfd76effa8 550 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 26 539 18.157 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 SMD11_RS06230 b20038d06003cbe7bee9ddcc96e9ab6e 260 Pfam PF12706 Beta-lactamase superfamily domain 20 209 1.7E-29 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS06230 b20038d06003cbe7bee9ddcc96e9ab6e 260 Gene3D G3DSA:3.60.15.10 3 255 9.5E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS06230 b20038d06003cbe7bee9ddcc96e9ab6e 260 SUPERFAMILY SSF56281 104 214 4.9E-23 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS06230 b20038d06003cbe7bee9ddcc96e9ab6e 260 SUPERFAMILY SSF56281 3 74 4.9E-23 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS13925 b15b314eabea002aa9ec1a6fdfa0dde9 315 Gene3D G3DSA:3.90.550.10 35 210 2.6E-12 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS13925 b15b314eabea002aa9ec1a6fdfa0dde9 315 Pfam PF00535 Glycosyl transferase family 2 36 155 2.5E-9 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD11_RS13925 b15b314eabea002aa9ec1a6fdfa0dde9 315 SUPERFAMILY SSF53448 35 281 1.0E-57 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS08760 13953af47cc0e11b01473328a4d5751f 297 SUPERFAMILY SSF101478 4 289 2.35E-53 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 SMD11_RS08760 13953af47cc0e11b01473328a4d5751f 297 Pfam PF03747 ADP-ribosylglycohydrolase 12 272 3.4E-44 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 SMD11_RS33220 509be12fc44fbbc8545087dd7f526492 269 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 2 244 1.1E-39 T 06-07-2017 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 SMD11_RS33220 509be12fc44fbbc8545087dd7f526492 269 Pfam PF02811 PHP domain 3 138 4.9E-10 T 06-07-2017 IPR004013 PHP domain GO:0003824 SMD11_RS33220 509be12fc44fbbc8545087dd7f526492 269 Gene3D G3DSA:3.20.20.140 1 261 3.3E-37 T 06-07-2017 SMD11_RS33220 509be12fc44fbbc8545087dd7f526492 269 SUPERFAMILY SSF89550 1 265 4.71E-43 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMD11_RS30910 c5871a6bc4047533db9a516af06c88ac 180 Pfam PF08768 Domain of unknown function (DUF1794) 26 178 3.1E-45 T 06-07-2017 IPR014878 Domain of unknown function DUF1794 SMD11_RS30910 c5871a6bc4047533db9a516af06c88ac 180 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 18 180 30.802 T 06-07-2017 IPR022939 Uncharacterised protein family UPF0678 SMD11_RS30910 c5871a6bc4047533db9a516af06c88ac 180 SUPERFAMILY SSF50814 23 178 2.75E-40 T 06-07-2017 IPR011038 Calycin-like SMD11_RS24935 d35b552c320cbd025fc85590d826b1cb 405 Gene3D G3DSA:3.40.50.2300 36 246 1.8E-57 T 06-07-2017 SMD11_RS24935 d35b552c320cbd025fc85590d826b1cb 405 SUPERFAMILY SSF53822 36 396 1.04E-75 T 06-07-2017 IPR028082 Periplasmic binding protein-like I SMD11_RS24935 d35b552c320cbd025fc85590d826b1cb 405 Pfam PF13458 Periplasmic binding protein 36 391 3.0E-54 T 06-07-2017 IPR028081 Leucine-binding protein domain SMD11_RS02775 36e80789b7b2803a7ca72ae5319c805f 138 Gene3D G3DSA:3.40.50.720 23 112 2.6E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS02775 36e80789b7b2803a7ca72ae5319c805f 138 SUPERFAMILY SSF51735 28 118 7.87E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS22115 e78243e7979569862b8d1d041216f076 451 Gene3D G3DSA:3.40.190.10 53 178 2.1E-17 T 06-07-2017 SMD11_RS22115 e78243e7979569862b8d1d041216f076 451 SUPERFAMILY SSF53850 43 443 1.14E-57 T 06-07-2017 SMD11_RS22115 e78243e7979569862b8d1d041216f076 451 Pfam PF01547 Bacterial extracellular solute-binding protein 63 359 6.4E-32 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 SMD11_RS22115 e78243e7979569862b8d1d041216f076 451 Gene3D G3DSA:3.40.190.10 179 380 1.8E-35 T 06-07-2017 SMD11_RS24710 1095cf2223a7feab303a5383af0794a6 186 Pfam PF07681 DoxX 33 118 9.7E-18 T 06-07-2017 IPR032808 DoxX family SMD11_RS01160 e0d6dcd1f8594b1fda524ebd2c89e045 140 Gene3D G3DSA:1.10.287.100 94 138 2.5E-15 T 06-07-2017 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 SMD11_RS01160 e0d6dcd1f8594b1fda524ebd2c89e045 140 SMART SM00347 22 124 7.6E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS01160 e0d6dcd1f8594b1fda524ebd2c89e045 140 Pfam PF12802 MarR family 31 86 4.2E-9 T 06-07-2017 SMD11_RS01160 e0d6dcd1f8594b1fda524ebd2c89e045 140 Gene3D G3DSA:1.10.10.10 32 92 7.1E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01160 e0d6dcd1f8594b1fda524ebd2c89e045 140 SUPERFAMILY SSF46785 16 138 5.3E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS10195 6597251a5421894e90e47129820188b2 240 SUPERFAMILY SSF116734 40 238 5.56E-23 T 06-07-2017 SMD11_RS06335 3dc00b64485dd903f8f0800784750df2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.8E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06335 3dc00b64485dd903f8f0800784750df2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.8E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06335 3dc00b64485dd903f8f0800784750df2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.8E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06335 3dc00b64485dd903f8f0800784750df2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.8E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06335 3dc00b64485dd903f8f0800784750df2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.8E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06335 3dc00b64485dd903f8f0800784750df2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.8E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06335 3dc00b64485dd903f8f0800784750df2 255 Gene3D G3DSA:3.40.50.720 1 246 4.2E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06335 3dc00b64485dd903f8f0800784750df2 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 1.0E-58 T 06-07-2017 SMD11_RS06335 3dc00b64485dd903f8f0800784750df2 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SMD11_RS06335 3dc00b64485dd903f8f0800784750df2 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 189 0.0038 T 06-07-2017 SMD11_RS06335 3dc00b64485dd903f8f0800784750df2 255 SUPERFAMILY SSF51735 6 245 5.41E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06335 3dc00b64485dd903f8f0800784750df2 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06335 3dc00b64485dd903f8f0800784750df2 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS06335 3dc00b64485dd903f8f0800784750df2 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16075 4102fab7bc5604cfa5901c882e9e4253 289 Pfam PF04539 Sigma-70 region 3 148 211 4.5E-14 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16075 4102fab7bc5604cfa5901c882e9e4253 289 Gene3D G3DSA:1.10.601.10 58 138 2.9E-25 T 06-07-2017 SMD11_RS16075 4102fab7bc5604cfa5901c882e9e4253 289 Gene3D G3DSA:1.10.10.10 226 283 3.7E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16075 4102fab7bc5604cfa5901c882e9e4253 289 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 63 284 3.6E-87 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16075 4102fab7bc5604cfa5901c882e9e4253 289 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 93 106 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16075 4102fab7bc5604cfa5901c882e9e4253 289 Pfam PF04545 Sigma-70, region 4 235 282 1.3E-15 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16075 4102fab7bc5604cfa5901c882e9e4253 289 PRINTS PR00046 Major sigma-70 factor signature 238 250 8.0E-8 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16075 4102fab7bc5604cfa5901c882e9e4253 289 PRINTS PR00046 Major sigma-70 factor signature 93 106 8.0E-8 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16075 4102fab7bc5604cfa5901c882e9e4253 289 PRINTS PR00046 Major sigma-70 factor signature 255 270 8.0E-8 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16075 4102fab7bc5604cfa5901c882e9e4253 289 SUPERFAMILY SSF88659 220 284 1.1E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16075 4102fab7bc5604cfa5901c882e9e4253 289 SUPERFAMILY SSF88659 142 215 1.53E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16075 4102fab7bc5604cfa5901c882e9e4253 289 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 66 283 3.7E-33 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16075 4102fab7bc5604cfa5901c882e9e4253 289 Pfam PF04542 Sigma-70 region 2 69 138 1.3E-18 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16075 4102fab7bc5604cfa5901c882e9e4253 289 SUPERFAMILY SSF88946 43 139 1.05E-30 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SMD11_RS16075 4102fab7bc5604cfa5901c882e9e4253 289 Gene3D G3DSA:1.10.10.10 139 192 2.0E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30395 d22a4187763bcbcdf37820bad01b1a7f 393 Pfam PF00144 Beta-lactamase 46 372 3.9E-64 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS30395 d22a4187763bcbcdf37820bad01b1a7f 393 Gene3D G3DSA:3.40.710.10 52 378 6.2E-77 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS30395 d22a4187763bcbcdf37820bad01b1a7f 393 SUPERFAMILY SSF56601 51 372 4.11E-77 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS25325 0d3083c38fcc32fe1b0e07c455f7e230 296 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 20 295 9.6E-150 T 06-07-2017 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 SMD11_RS25325 0d3083c38fcc32fe1b0e07c455f7e230 296 SUPERFAMILY SSF51197 29 294 4.76E-61 T 06-07-2017 SMD11_RS25325 0d3083c38fcc32fe1b0e07c455f7e230 296 Gene3D G3DSA:2.60.120.620 34 275 6.7E-52 T 06-07-2017 SMD11_RS25325 0d3083c38fcc32fe1b0e07c455f7e230 296 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 44 259 1.2E-36 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase SMD11_RS23070 6b60b8ffdb8e771fc502a6d271559a6d 198 SUPERFAMILY SSF53254 3 197 1.3E-49 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS23070 6b60b8ffdb8e771fc502a6d271559a6d 198 SMART SM00855 3 156 5.9E-23 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS23070 6b60b8ffdb8e771fc502a6d271559a6d 198 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 195 2.6E-52 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS23070 6b60b8ffdb8e771fc502a6d271559a6d 198 Gene3D G3DSA:3.40.50.1240 3 194 2.2E-46 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS06455 edabecee692f402d1bf5577f3536ac73 176 Gene3D G3DSA:2.160.10.10 7 173 3.3E-46 T 06-07-2017 SMD11_RS06455 edabecee692f402d1bf5577f3536ac73 176 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 92 125 2.3E-7 T 06-07-2017 IPR001451 Hexapeptide repeat SMD11_RS06455 edabecee692f402d1bf5577f3536ac73 176 SUPERFAMILY SSF51161 9 172 2.22E-47 T 06-07-2017 IPR011004 Trimeric LpxA-like SMD11_RS16065 ef1ff19228a65583b968787758806492 123 SUPERFAMILY SSF52091 11 108 2.16E-18 T 06-07-2017 IPR002645 STAS domain SMD11_RS16065 ef1ff19228a65583b968787758806492 123 Gene3D G3DSA:3.30.750.24 10 108 6.0E-24 T 06-07-2017 IPR002645 STAS domain SMD11_RS16065 ef1ff19228a65583b968787758806492 123 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 10 108 1.6E-20 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMD11_RS16065 ef1ff19228a65583b968787758806492 123 Pfam PF13466 STAS domain 21 100 3.9E-14 T 06-07-2017 IPR002645 STAS domain SMD11_RS31290 6d0f2189ee9dbc04c45786586d1933fa 183 Gene3D G3DSA:3.40.30.10 93 163 2.3E-8 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS31290 6d0f2189ee9dbc04c45786586d1933fa 183 Gene3D G3DSA:3.40.30.10 45 92 4.1E-5 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS31290 6d0f2189ee9dbc04c45786586d1933fa 183 ProSitePatterns PS00194 Thioredoxin family active site. 79 97 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 SMD11_RS31290 6d0f2189ee9dbc04c45786586d1933fa 183 SUPERFAMILY SSF52833 53 166 1.25E-11 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS12510 9bd05f2ba41f64c2c9a0fb30e8ff3627 289 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 151 239 5.3E-17 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 SMD11_RS12510 9bd05f2ba41f64c2c9a0fb30e8ff3627 289 Gene3D G3DSA:3.40.140.10 148 250 7.5E-25 T 06-07-2017 SMD11_RS12510 9bd05f2ba41f64c2c9a0fb30e8ff3627 289 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 193 228 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SMD11_RS12510 9bd05f2ba41f64c2c9a0fb30e8ff3627 289 SUPERFAMILY SSF53927 147 254 7.36E-26 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 SMD11_RS13300 807f9b8d0b3ecb5693981d7fa2f11f23 365 SUPERFAMILY SSF54001 249 357 2.55E-41 T 06-07-2017 SMD11_RS13300 807f9b8d0b3ecb5693981d7fa2f11f23 365 Pfam PF00877 NlpC/P60 family 265 356 2.0E-25 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS13300 807f9b8d0b3ecb5693981d7fa2f11f23 365 Gene3D G3DSA:3.90.1720.10 248 355 5.3E-44 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS03095 88e431c225d3bdb4e16dc86ac34b6da8 665 SUPERFAMILY SSF53448 4 207 1.69E-43 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS03095 88e431c225d3bdb4e16dc86ac34b6da8 665 Gene3D G3DSA:3.90.550.10 3 196 3.6E-41 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS03095 88e431c225d3bdb4e16dc86ac34b6da8 665 Pfam PF00535 Glycosyl transferase family 2 7 139 2.4E-32 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD11_RS21395 2112ebd5fbf45855c348a707741171ad 270 Pfam PF02096 60Kd inner membrane protein 40 248 4.6E-24 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SMD11_RS21395 2112ebd5fbf45855c348a707741171ad 270 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 39 248 1.3E-28 T 06-07-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal SMD11_RS32115 b348e5cddf09d39a547eeb7dc282727b 387 SUPERFAMILY SSF56601 49 372 7.52E-77 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS32115 b348e5cddf09d39a547eeb7dc282727b 387 Gene3D G3DSA:3.40.710.10 56 374 6.7E-80 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS32115 b348e5cddf09d39a547eeb7dc282727b 387 Pfam PF00144 Beta-lactamase 47 381 7.0E-64 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS22435 b400c7867d177fc40fadd00b7ac239e6 261 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 3 191 4.3E-49 T 06-07-2017 IPR018768 Domain of unknown function DUF2344 SMD11_RS22435 b400c7867d177fc40fadd00b7ac239e6 261 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 3 216 1.7E-54 T 06-07-2017 IPR018768 Domain of unknown function DUF2344 SMD11_RS16830 eb28ddc68f3dad8c58770adceaa249a6 744 Pfam PF03023 MviN-like protein 230 701 3.0E-119 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD11_RS16830 eb28ddc68f3dad8c58770adceaa249a6 744 PRINTS PR01806 Virulence factor MviN signature 235 254 3.0E-21 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD11_RS16830 eb28ddc68f3dad8c58770adceaa249a6 744 PRINTS PR01806 Virulence factor MviN signature 483 509 3.0E-21 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD11_RS16830 eb28ddc68f3dad8c58770adceaa249a6 744 PRINTS PR01806 Virulence factor MviN signature 358 379 3.0E-21 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD11_RS16830 eb28ddc68f3dad8c58770adceaa249a6 744 PRINTS PR01806 Virulence factor MviN signature 254 270 3.0E-21 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD11_RS16830 eb28ddc68f3dad8c58770adceaa249a6 744 PRINTS PR01806 Virulence factor MviN signature 334 358 3.0E-21 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD11_RS16830 eb28ddc68f3dad8c58770adceaa249a6 744 PRINTS PR01806 Virulence factor MviN signature 579 598 3.0E-21 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD11_RS16830 eb28ddc68f3dad8c58770adceaa249a6 744 PRINTS PR01806 Virulence factor MviN signature 635 652 3.0E-21 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD11_RS16830 eb28ddc68f3dad8c58770adceaa249a6 744 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 204 734 7.2E-135 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ SMD11_RS19400 a4f5e96679be7e81c28d1ee4ca0a4ca2 179 Pfam PF04075 Domain of unknown function (DUF385) 46 154 3.1E-27 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD11_RS19400 a4f5e96679be7e81c28d1ee4ca0a4ca2 179 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 47 156 2.8E-28 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD11_RS21645 daacc2caf2954597eb8cc42a47813f18 478 Gene3D G3DSA:1.25.40.10 240 321 2.8E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS21645 daacc2caf2954597eb8cc42a47813f18 478 Gene3D G3DSA:1.25.40.10 374 436 2.8E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS21645 daacc2caf2954597eb8cc42a47813f18 478 SUPERFAMILY SSF48452 243 349 6.64E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS08675 d0acfe838db954080fffa38472841755 289 Gene3D G3DSA:1.10.3720.10 85 277 5.4E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS08675 d0acfe838db954080fffa38472841755 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 277 2.3E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS08675 d0acfe838db954080fffa38472841755 289 SUPERFAMILY SSF161098 85 266 1.7E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS31180 ed8d7f9fa93b1c5f768752ef50b0a240 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 2.0E-6 T 06-07-2017 SMD11_RS31180 ed8d7f9fa93b1c5f768752ef50b0a240 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 19 38 2.0E-6 T 06-07-2017 SMD11_RS31180 ed8d7f9fa93b1c5f768752ef50b0a240 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 215 233 2.0E-6 T 06-07-2017 SMD11_RS31180 ed8d7f9fa93b1c5f768752ef50b0a240 454 SUPERFAMILY SSF51905 289 437 6.4E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31180 ed8d7f9fa93b1c5f768752ef50b0a240 454 SUPERFAMILY SSF51905 159 246 6.4E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31180 ed8d7f9fa93b1c5f768752ef50b0a240 454 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 18 362 4.6E-106 T 06-07-2017 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase SMD11_RS31180 ed8d7f9fa93b1c5f768752ef50b0a240 454 Gene3D G3DSA:3.50.50.60 295 399 3.2E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31180 ed8d7f9fa93b1c5f768752ef50b0a240 454 Gene3D G3DSA:3.50.50.60 223 263 3.2E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31180 ed8d7f9fa93b1c5f768752ef50b0a240 454 Gene3D G3DSA:3.50.50.60 82 222 2.7E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31180 ed8d7f9fa93b1c5f768752ef50b0a240 454 SUPERFAMILY SSF51905 18 257 2.85E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS09420 cd8e8b99f2206d3e4fae502baa4c94cf 117 SUPERFAMILY SSF51182 6 115 2.72E-25 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS09420 cd8e8b99f2206d3e4fae502baa4c94cf 117 Pfam PF07883 Cupin domain 38 107 1.3E-16 T 06-07-2017 IPR013096 Cupin 2, conserved barrel SMD11_RS09420 cd8e8b99f2206d3e4fae502baa4c94cf 117 Gene3D G3DSA:2.60.120.10 31 112 3.1E-23 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS14450 92c698bedebbdbfad272b8eef57509f4 327 Gene3D G3DSA:3.30.70.1400 51 136 2.0E-12 T 06-07-2017 SMD11_RS14450 92c698bedebbdbfad272b8eef57509f4 327 Pfam PF01571 Aminomethyltransferase folate-binding domain 25 146 1.6E-18 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal SMD11_RS14450 92c698bedebbdbfad272b8eef57509f4 327 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 229 308 4.8E-8 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 SMD11_RS14450 92c698bedebbdbfad272b8eef57509f4 327 SUPERFAMILY SSF103025 27 245 4.87E-54 T 06-07-2017 SMD11_RS14450 92c698bedebbdbfad272b8eef57509f4 327 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 191 255 1.1E-21 T 06-07-2017 IPR017703 YgfZ/GcvT conserved site SMD11_RS04265 0b4d64acd3eeac30d6fb3bb9d69aab64 900 SMART SM00028 684 717 72.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS04265 0b4d64acd3eeac30d6fb3bb9d69aab64 900 SMART SM00028 724 757 0.059 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS04265 0b4d64acd3eeac30d6fb3bb9d69aab64 900 SMART SM00028 844 877 280.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 SMD11_RS04265 0b4d64acd3eeac30d6fb3bb9d69aab64 900 Gene3D G3DSA:1.25.40.10 671 874 3.0E-17 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS04265 0b4d64acd3eeac30d6fb3bb9d69aab64 900 Pfam PF13424 Tetratricopeptide repeat 691 755 2.0E-11 T 06-07-2017 SMD11_RS04265 0b4d64acd3eeac30d6fb3bb9d69aab64 900 Gene3D G3DSA:3.40.50.300 248 299 6.9E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04265 0b4d64acd3eeac30d6fb3bb9d69aab64 900 SUPERFAMILY SSF52540 222 482 6.71E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04265 0b4d64acd3eeac30d6fb3bb9d69aab64 900 SUPERFAMILY SSF48452 682 875 1.14E-15 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS14930 e505f93ec81ef4f567679267fbb8df30 157 SUPERFAMILY SSF54427 6 139 3.64E-38 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS14930 e505f93ec81ef4f567679267fbb8df30 157 Gene3D G3DSA:3.10.450.50 4 148 2.6E-50 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS14930 e505f93ec81ef4f567679267fbb8df30 157 Pfam PF13474 SnoaL-like domain 11 139 8.6E-30 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain SMD11_RS05230 ed85b9dfa5b8d2461312f37857a4fa63 116 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 10 76 2.5E-20 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS05230 ed85b9dfa5b8d2461312f37857a4fa63 116 Gene3D G3DSA:1.10.260.40 35 75 4.9E-4 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS22960 7cdcf16d19f5b7aeca8ec0c4e3835f7f 421 Pfam PF01547 Bacterial extracellular solute-binding protein 57 321 1.8E-31 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 SMD11_RS22960 7cdcf16d19f5b7aeca8ec0c4e3835f7f 421 SUPERFAMILY SSF53850 44 409 4.84E-58 T 06-07-2017 SMD11_RS22960 7cdcf16d19f5b7aeca8ec0c4e3835f7f 421 Gene3D G3DSA:3.40.190.10 148 308 4.5E-33 T 06-07-2017 SMD11_RS22960 7cdcf16d19f5b7aeca8ec0c4e3835f7f 421 Gene3D G3DSA:3.40.190.10 309 351 9.0E-23 T 06-07-2017 SMD11_RS22960 7cdcf16d19f5b7aeca8ec0c4e3835f7f 421 Gene3D G3DSA:3.40.190.10 44 147 9.0E-23 T 06-07-2017 SMD11_RS01295 b188679b3f7c15d1bc08f7761f534bc8 473 SUPERFAMILY SSF103473 16 446 1.05E-53 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS01295 b188679b3f7c15d1bc08f7761f534bc8 473 Pfam PF07690 Major Facilitator Superfamily 81 395 6.3E-25 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS01295 b188679b3f7c15d1bc08f7761f534bc8 473 Gene3D G3DSA:1.20.1250.20 39 234 2.4E-21 T 06-07-2017 SMD11_RS01295 b188679b3f7c15d1bc08f7761f534bc8 473 Gene3D G3DSA:1.20.1250.20 258 446 6.1E-14 T 06-07-2017 SMD11_RS01295 b188679b3f7c15d1bc08f7761f534bc8 473 ProSitePatterns PS00217 Sugar transport proteins signature 2. 145 170 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS19590 988920abeff1ad8b12658b49e27633f6 179 Pfam PF16919 Protein kinase G rubredoxin domain 91 177 5.3E-18 T 06-07-2017 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 SMD11_RS26165 e26965aec3ef62739a80f11388bf1bfb 262 PIRSF PIRSF006648 2 262 4.5E-63 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS26165 e26965aec3ef62739a80f11388bf1bfb 262 Pfam PF01061 ABC-2 type transporter 10 216 6.8E-30 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD11_RS23315 c3d4f55c05342920c521c106687e30af 267 SUPERFAMILY SSF56784 41 232 1.91E-13 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS23315 c3d4f55c05342920c521c106687e30af 267 SUPERFAMILY SSF56784 4 14 1.91E-13 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS23315 c3d4f55c05342920c521c106687e30af 267 Gene3D G3DSA:3.40.50.1000 4 99 3.7E-9 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS23315 c3d4f55c05342920c521c106687e30af 267 Gene3D G3DSA:3.40.50.1000 180 236 3.7E-9 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS23315 c3d4f55c05342920c521c106687e30af 267 PIRSF PIRSF030802 1 241 1.6E-14 T 06-07-2017 IPR024197 Uncharacterised conserved protein UCP030802 SMD11_RS01515 47c5155c651e4155c9c91a86f6bc35c0 723 Gene3D G3DSA:3.40.50.300 664 722 1.9E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01515 47c5155c651e4155c9c91a86f6bc35c0 723 SUPERFAMILY SSF52540 340 405 1.65E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01515 47c5155c651e4155c9c91a86f6bc35c0 723 SUPERFAMILY SSF52540 188 268 1.65E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01515 47c5155c651e4155c9c91a86f6bc35c0 723 SUPERFAMILY SSF52540 497 722 1.65E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01515 47c5155c651e4155c9c91a86f6bc35c0 723 Gene3D G3DSA:3.40.50.300 189 270 4.0E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01515 47c5155c651e4155c9c91a86f6bc35c0 723 Gene3D G3DSA:3.40.50.300 342 372 4.0E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01515 47c5155c651e4155c9c91a86f6bc35c0 723 Gene3D G3DSA:3.40.50.300 512 607 4.0E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01515 47c5155c651e4155c9c91a86f6bc35c0 723 Pfam PF13245 Part of AAA domain 201 268 5.6E-14 T 06-07-2017 SMD11_RS04505 41474c308846a12ab651ba1f9c33cdd2 186 SUPERFAMILY SSF53254 34 181 1.73E-21 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS04505 41474c308846a12ab651ba1f9c33cdd2 186 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 33 181 2.3E-16 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS04505 41474c308846a12ab651ba1f9c33cdd2 186 Gene3D G3DSA:3.40.50.1240 42 181 3.8E-17 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS23215 cbf3baf17ea001573aae817cd6873b33 272 Pfam PF00144 Beta-lactamase 13 262 7.3E-41 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS23215 cbf3baf17ea001573aae817cd6873b33 272 Gene3D G3DSA:3.40.710.10 6 265 1.5E-50 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS23215 cbf3baf17ea001573aae817cd6873b33 272 SUPERFAMILY SSF56601 6 265 1.99E-57 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS08120 09c44fa7fc8befceb979d6e8837d033f 351 SUPERFAMILY SSF51569 51 345 5.86E-9 T 06-07-2017 SMD11_RS08120 09c44fa7fc8befceb979d6e8837d033f 351 Hamap MF_00493 Transaldolase [tal]. 1 351 52.691 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS08120 09c44fa7fc8befceb979d6e8837d033f 351 Pfam PF00923 Transaldolase 49 342 1.8E-8 T 06-07-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 SMD11_RS08120 09c44fa7fc8befceb979d6e8837d033f 351 Gene3D G3DSA:3.20.20.70 3 344 1.3E-31 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 PRINTS PR00385 P450 superfamily signature 238 255 4.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 PRINTS PR00385 P450 superfamily signature 332 341 4.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 PRINTS PR00385 P450 superfamily signature 341 352 4.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 PRINTS PR00385 P450 superfamily signature 265 276 4.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 PRINTS PR00359 B-class P450 signature 141 157 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 PRINTS PR00359 B-class P450 signature 158 173 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 PRINTS PR00359 B-class P450 signature 283 310 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 PRINTS PR00359 B-class P450 signature 311 326 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 PRINTS PR00359 B-class P450 signature 341 352 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 PRINTS PR00359 B-class P450 signature 196 218 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 PRINTS PR00359 B-class P450 signature 94 105 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 PRINTS PR00359 B-class P450 signature 332 341 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 SUPERFAMILY SSF48264 19 392 2.75E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 334 343 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 Gene3D G3DSA:1.10.630.10 6 392 4.4E-108 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS32360 fb1a71a18af1abe7dbc71ddb20bd7786 392 Pfam PF00067 Cytochrome P450 265 360 6.1E-18 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06070 b5079ad75c489ddc32266eba617726e6 1250 Gene3D G3DSA:1.10.530.10 1159 1244 1.4E-5 T 06-07-2017 SMD11_RS06070 b5079ad75c489ddc32266eba617726e6 1250 Pfam PF05257 CHAP domain 1006 1093 1.1E-6 T 06-07-2017 IPR007921 CHAP domain SMD11_RS06070 b5079ad75c489ddc32266eba617726e6 1250 Pfam PF01464 Transglycosylase SLT domain 1184 1245 1.1E-5 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 SMD11_RS06070 b5079ad75c489ddc32266eba617726e6 1250 SUPERFAMILY SSF53955 1169 1249 5.91E-9 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS03640 87ecbae822a3c13e3a5aea1ab2683d63 436 ProSitePatterns PS00216 Sugar transport proteins signature 1. 295 311 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS03640 87ecbae822a3c13e3a5aea1ab2683d63 436 Pfam PF07690 Major Facilitator Superfamily 44 287 1.2E-20 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS03640 87ecbae822a3c13e3a5aea1ab2683d63 436 Gene3D G3DSA:1.20.1250.20 242 421 2.2E-17 T 06-07-2017 SMD11_RS03640 87ecbae822a3c13e3a5aea1ab2683d63 436 Gene3D G3DSA:1.20.1250.20 37 219 1.4E-20 T 06-07-2017 SMD11_RS03640 87ecbae822a3c13e3a5aea1ab2683d63 436 SUPERFAMILY SSF103473 36 419 4.05E-47 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS25925 618a1d54beab1d7ea1d3b3106f5d59ca 250 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 3 248 1.2E-61 T 06-07-2017 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 SMD11_RS32235 c937a7780b476f666f8a3eb708e45460 390 Pfam PF01494 FAD binding domain 8 341 5.3E-23 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS32235 c937a7780b476f666f8a3eb708e45460 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.4E-16 T 06-07-2017 SMD11_RS32235 c937a7780b476f666f8a3eb708e45460 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 1.4E-16 T 06-07-2017 SMD11_RS32235 c937a7780b476f666f8a3eb708e45460 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 1.4E-16 T 06-07-2017 SMD11_RS32235 c937a7780b476f666f8a3eb708e45460 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 1.4E-16 T 06-07-2017 SMD11_RS32235 c937a7780b476f666f8a3eb708e45460 390 SUPERFAMILY SSF51905 267 372 2.79E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS32235 c937a7780b476f666f8a3eb708e45460 390 SUPERFAMILY SSF51905 6 171 2.79E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS32235 c937a7780b476f666f8a3eb708e45460 390 Gene3D G3DSA:3.50.50.60 7 177 9.0E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS32235 c937a7780b476f666f8a3eb708e45460 390 Gene3D G3DSA:3.50.50.60 267 346 9.0E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS05355 b1483ae7888be80834e3e5aaf9819f22 311 Pfam PF01061 ABC-2 type transporter 60 269 6.2E-16 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD11_RS14155 a0bfa7561af2171531debebbc32dfcd8 160 SMART SM01058 2 112 1.2E-32 T 06-07-2017 IPR003711 CarD-like/TRCF domain SMD11_RS14155 a0bfa7561af2171531debebbc32dfcd8 160 SUPERFAMILY SSF141259 2 65 3.66E-15 T 06-07-2017 IPR003711 CarD-like/TRCF domain SMD11_RS14155 a0bfa7561af2171531debebbc32dfcd8 160 Pfam PF02559 CarD-like/TRCF domain 3 110 1.4E-15 T 06-07-2017 IPR003711 CarD-like/TRCF domain SMD11_RS21205 73b63cc5196a8d33095782d241cd73fc 103 SUPERFAMILY SSF54736 25 99 3.92E-24 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMD11_RS21205 73b63cc5196a8d33095782d241cd73fc 103 Gene3D G3DSA:3.30.1390.10 22 102 7.5E-28 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SMD11_RS21205 73b63cc5196a8d33095782d241cd73fc 103 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 12 103 16.874 T 06-07-2017 IPR022935 ATP-dependent Clp protease adaptor protein ClpS SMD11_RS21205 73b63cc5196a8d33095782d241cd73fc 103 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 28 97 1.1E-21 T 06-07-2017 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 SMD11_RS17170 a21e120ee7b5eac5cc27ffd5f909ab75 385 Gene3D G3DSA:3.40.50.970 31 363 2.1E-119 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS17170 a21e120ee7b5eac5cc27ffd5f909ab75 385 SUPERFAMILY SSF52518 45 367 5.9E-93 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS17170 a21e120ee7b5eac5cc27ffd5f909ab75 385 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 40 364 7.0E-128 T 06-07-2017 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMD11_RS17170 a21e120ee7b5eac5cc27ffd5f909ab75 385 Pfam PF00676 Dehydrogenase E1 component 67 342 2.3E-74 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 SMD11_RS09480 523d9ec7eafefdab54cdefe798cb604b 345 Pfam PF00005 ABC transporter 19 161 6.3E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS09480 523d9ec7eafefdab54cdefe798cb604b 345 SUPERFAMILY SSF52540 3 241 1.33E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09480 523d9ec7eafefdab54cdefe798cb604b 345 SMART SM00382 28 211 5.5E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS09480 523d9ec7eafefdab54cdefe798cb604b 345 Pfam PF08402 TOBE domain 269 342 4.1E-10 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SMD11_RS09480 523d9ec7eafefdab54cdefe798cb604b 345 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS09480 523d9ec7eafefdab54cdefe798cb604b 345 SUPERFAMILY SSF50331 238 343 1.04E-9 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal SMD11_RS09480 523d9ec7eafefdab54cdefe798cb604b 345 Gene3D G3DSA:3.40.50.300 3 234 2.1E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27730 35a72abf1918c683368005df763c71cb 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS27730 35a72abf1918c683368005df763c71cb 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS27730 35a72abf1918c683368005df763c71cb 507 Gene3D G3DSA:3.40.605.10 19 271 4.3E-92 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS27730 35a72abf1918c683368005df763c71cb 507 Gene3D G3DSA:3.40.309.10 272 470 2.7E-56 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS27730 35a72abf1918c683368005df763c71cb 507 Pfam PF00171 Aldehyde dehydrogenase family 31 494 2.6E-158 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS27730 35a72abf1918c683368005df763c71cb 507 SUPERFAMILY SSF53720 14 499 8.9E-159 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS15000 29bcb95d75d81ae0d0eb9cd6d0be6b21 102 SUPERFAMILY SSF53383 4 85 1.84E-14 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS24180 7ba98092795e1abc6fa2adf872a88df1 324 Pfam PF00294 pfkB family carbohydrate kinase 32 295 5.1E-41 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB SMD11_RS24180 7ba98092795e1abc6fa2adf872a88df1 324 SUPERFAMILY SSF53613 2 295 5.46E-54 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS24180 7ba98092795e1abc6fa2adf872a88df1 324 Gene3D G3DSA:3.40.1190.20 2 307 1.3E-45 T 06-07-2017 IPR029056 Ribokinase-like SMD11_RS26730 4d0cfc44f1edd4e5865e6af1607e371f 373 SUPERFAMILY SSF46589 29 114 4.45E-12 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 SMD11_RS26730 4d0cfc44f1edd4e5865e6af1607e371f 373 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 37 104 3.9E-15 T 06-07-2017 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SMD11_RS26730 4d0cfc44f1edd4e5865e6af1607e371f 373 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 68 367 1.5E-88 T 06-07-2017 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 SMD11_RS26730 4d0cfc44f1edd4e5865e6af1607e371f 373 Pfam PF01409 tRNA synthetases class II core domain (F) 109 368 3.5E-103 T 06-07-2017 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 SMD11_RS26730 4d0cfc44f1edd4e5865e6af1607e371f 373 Gene3D G3DSA:3.30.930.10 25 370 7.3E-119 T 06-07-2017 SMD11_RS26730 4d0cfc44f1edd4e5865e6af1607e371f 373 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 25 369 45.133 T 06-07-2017 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 SMD11_RS26730 4d0cfc44f1edd4e5865e6af1607e371f 373 SUPERFAMILY SSF55681 110 370 4.66E-75 T 06-07-2017 SMD11_RS17160 d1cec1ced263094bb6496bf0e0ef97ae 196 SUPERFAMILY SSF48498 83 193 8.35E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS17160 d1cec1ced263094bb6496bf0e0ef97ae 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 2.2E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS17160 d1cec1ced263094bb6496bf0e0ef97ae 196 SUPERFAMILY SSF46689 2 74 9.98E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS17160 d1cec1ced263094bb6496bf0e0ef97ae 196 Gene3D G3DSA:1.10.357.10 60 194 1.7E-45 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS17160 d1cec1ced263094bb6496bf0e0ef97ae 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.9E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS17160 d1cec1ced263094bb6496bf0e0ef97ae 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.9E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS17160 d1cec1ced263094bb6496bf0e0ef97ae 196 Gene3D G3DSA:1.10.10.60 10 59 3.9E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS20400 b01cea6b82220a4ff267ccc0f3728579 398 SUPERFAMILY SSF103473 4 379 3.66E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS20400 b01cea6b82220a4ff267ccc0f3728579 398 Pfam PF07690 Major Facilitator Superfamily 9 337 3.4E-39 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS20400 b01cea6b82220a4ff267ccc0f3728579 398 Gene3D G3DSA:1.20.1250.20 4 178 3.4E-31 T 06-07-2017 SMD11_RS20400 b01cea6b82220a4ff267ccc0f3728579 398 Gene3D G3DSA:1.20.1250.20 197 379 1.3E-8 T 06-07-2017 SMD11_RS10265 d72a7ab46cec959f889402f63a02911f 331 SUPERFAMILY SSF161098 114 312 6.15E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS10265 d72a7ab46cec959f889402f63a02911f 331 Gene3D G3DSA:1.10.3720.10 110 327 2.6E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS10265 d72a7ab46cec959f889402f63a02911f 331 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 137 328 7.4E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS10265 d72a7ab46cec959f889402f63a02911f 331 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 30 66 5.7E-13 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SMD11_RS30145 d315207605ddfe85629b5952f59ec763 414 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 79 270 6.6E-18 T 06-07-2017 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system SMD11_RS19305 9144d9b10cee99c59ad9bfebfeb4df5e 528 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 06-07-2017 IPR020845 AMP-binding, conserved site SMD11_RS19305 9144d9b10cee99c59ad9bfebfeb4df5e 528 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 507 1.0E-12 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain SMD11_RS19305 9144d9b10cee99c59ad9bfebfeb4df5e 528 Pfam PF00501 AMP-binding enzyme 19 424 1.1E-72 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SMD11_RS19305 9144d9b10cee99c59ad9bfebfeb4df5e 528 Gene3D G3DSA:3.40.50.980 12 185 7.7E-26 T 06-07-2017 SMD11_RS19305 9144d9b10cee99c59ad9bfebfeb4df5e 528 Gene3D G3DSA:3.30.300.30 419 521 3.3E-24 T 06-07-2017 SMD11_RS19305 9144d9b10cee99c59ad9bfebfeb4df5e 528 Gene3D G3DSA:2.30.38.10 345 418 1.3E-20 T 06-07-2017 SMD11_RS19305 9144d9b10cee99c59ad9bfebfeb4df5e 528 Gene3D G3DSA:3.40.50.980 186 337 6.3E-26 T 06-07-2017 SMD11_RS19305 9144d9b10cee99c59ad9bfebfeb4df5e 528 SUPERFAMILY SSF56801 12 521 7.85E-119 T 06-07-2017 SMD11_RS26845 c9456420a4b44e89f369f56b1abb6d2e 197 Pfam PF07040 Protein of unknown function (DUF1326) 12 180 2.8E-40 T 06-07-2017 IPR009758 Protein of unknown function DUF1326 SMD11_RS24520 f340460a86449fabbcc0b86c03a5a894 284 Pfam PF03799 Cell division protein FtsQ 154 264 1.1E-5 T 06-07-2017 IPR005548 Cell division protein FtsQ/DivIB SMD11_RS24520 f340460a86449fabbcc0b86c03a5a894 284 Pfam PF08478 POTRA domain, FtsQ-type 82 150 3.0E-17 T 06-07-2017 IPR013685 Polypeptide-transport-associated, FtsQ-type SMD11_RS24520 f340460a86449fabbcc0b86c03a5a894 284 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 51 282 18.697 T 06-07-2017 IPR026579 Cell division protein FtsQ GO:0090529 SMD11_RS29100 eaa1a6d93858a249400245e944ff7b11 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 270 8.5E-52 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS29100 eaa1a6d93858a249400245e944ff7b11 272 SUPERFAMILY SSF52096 4 270 6.64E-80 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS29100 eaa1a6d93858a249400245e944ff7b11 272 Gene3D G3DSA:3.90.226.10 4 270 1.1E-79 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS31430 1b054834bc39d3614f30be65d45ee8c1 230 SUPERFAMILY SSF102114 45 123 1.96E-9 T 06-07-2017 SMD11_RS31430 1b054834bc39d3614f30be65d45ee8c1 230 Gene3D G3DSA:3.20.20.70 45 125 1.1E-8 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS31430 1b054834bc39d3614f30be65d45ee8c1 230 Pfam PF04055 Radical SAM superfamily 43 135 9.1E-8 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS31430 1b054834bc39d3614f30be65d45ee8c1 230 Pfam PF13353 4Fe-4S single cluster domain 36 171 2.6E-26 T 06-07-2017 SMD11_RS10130 95c5e4e7d432b6c9b460da641c60c5a7 499 Pfam PF01425 Amidase 26 473 2.6E-157 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS10130 95c5e4e7d432b6c9b460da641c60c5a7 499 Gene3D G3DSA:3.90.1300.10 2 487 2.3E-174 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS10130 95c5e4e7d432b6c9b460da641c60c5a7 499 SUPERFAMILY SSF75304 1 484 9.81E-162 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS10130 95c5e4e7d432b6c9b460da641c60c5a7 499 ProSitePatterns PS00571 Amidases signature. 153 184 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMD11_RS10130 95c5e4e7d432b6c9b460da641c60c5a7 499 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 485 90.138 T 06-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS10130 95c5e4e7d432b6c9b460da641c60c5a7 499 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 14 485 1.8E-184 T 06-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS10720 441b3fd558ff424da2392db046d08582 341 SUPERFAMILY SSF51679 1 340 5.77E-71 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS10720 441b3fd558ff424da2392db046d08582 341 Gene3D G3DSA:3.20.20.30 1 340 2.2E-89 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS10720 441b3fd558ff424da2392db046d08582 341 Pfam PF00296 Luciferase-like monooxygenase 1 310 1.2E-56 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS11620 732fbd10b00fe04c9d8a740079d682e3 131 Gene3D G3DSA:1.10.1660.10 5 55 2.3E-7 T 06-07-2017 SMD11_RS11620 732fbd10b00fe04c9d8a740079d682e3 131 SUPERFAMILY SSF46955 5 55 2.11E-10 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS11620 732fbd10b00fe04c9d8a740079d682e3 131 Gene3D G3DSA:2.40.50.100 66 128 3.9E-23 T 06-07-2017 SMD11_RS11620 732fbd10b00fe04c9d8a740079d682e3 131 Pfam PF03459 TOBE domain 66 128 2.0E-17 T 06-07-2017 IPR005116 Transport-associated OB, type 1 SMD11_RS11620 732fbd10b00fe04c9d8a740079d682e3 131 Pfam PF00376 MerR family regulatory protein 7 41 8.6E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS11620 732fbd10b00fe04c9d8a740079d682e3 131 SUPERFAMILY SSF50331 66 129 1.31E-17 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal SMD11_RS11620 732fbd10b00fe04c9d8a740079d682e3 131 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 66 128 6.7E-16 T 06-07-2017 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 SMD11_RS30245 2f72d39ea0eb4543cd39207f9ec2cf26 457 Gene3D G3DSA:1.20.1250.20 243 436 1.0E-22 T 06-07-2017 SMD11_RS30245 2f72d39ea0eb4543cd39207f9ec2cf26 457 Gene3D G3DSA:1.20.1250.20 11 214 3.2E-20 T 06-07-2017 SMD11_RS30245 2f72d39ea0eb4543cd39207f9ec2cf26 457 Pfam PF00083 Sugar (and other) transporter 13 436 3.4E-29 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 SMD11_RS30245 2f72d39ea0eb4543cd39207f9ec2cf26 457 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS30245 2f72d39ea0eb4543cd39207f9ec2cf26 457 SUPERFAMILY SSF103473 10 437 4.97E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS26190 44156fe42eb1a000e0de74fdcd996168 444 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 17 444 71.355 T 06-07-2017 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5 SMD11_RS26190 44156fe42eb1a000e0de74fdcd996168 444 Gene3D G3DSA:2.60.120.10 292 412 3.6E-67 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS26190 44156fe42eb1a000e0de74fdcd996168 444 Gene3D G3DSA:2.60.120.10 206 231 3.6E-67 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS26190 44156fe42eb1a000e0de74fdcd996168 444 SUPERFAMILY SSF51182 17 443 6.23E-163 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS26190 44156fe42eb1a000e0de74fdcd996168 444 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 17 442 3.9E-217 T 06-07-2017 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 SMD11_RS26190 44156fe42eb1a000e0de74fdcd996168 444 Pfam PF04209 homogentisate 1,2-dioxygenase 17 442 1.2E-212 T 06-07-2017 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 SMD11_RS21670 0354564ea78c06eece09978c36dee249 330 SUPERFAMILY SSF161098 86 315 8.63E-57 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21670 0354564ea78c06eece09978c36dee249 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 327 3.8E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS21670 0354564ea78c06eece09978c36dee249 330 Gene3D G3DSA:1.10.3720.10 42 316 1.2E-54 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS28885 d297fed40f1567ca50bb3a6acd87f4e5 215 Gene3D G3DSA:1.10.357.10 2 203 3.3E-47 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS28885 d297fed40f1567ca50bb3a6acd87f4e5 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 33 62 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD11_RS28885 d297fed40f1567ca50bb3a6acd87f4e5 215 SUPERFAMILY SSF48498 87 201 3.93E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS28885 d297fed40f1567ca50bb3a6acd87f4e5 215 SUPERFAMILY SSF46689 10 91 1.5E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS28885 d297fed40f1567ca50bb3a6acd87f4e5 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS28885 d297fed40f1567ca50bb3a6acd87f4e5 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS28885 d297fed40f1567ca50bb3a6acd87f4e5 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 2.5E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS16025 6b68b7b8f927d89802ee2ce745793bd9 142 SUPERFAMILY SSF69118 3 139 1.44E-43 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS16025 6b68b7b8f927d89802ee2ce745793bd9 142 Pfam PF02627 Carboxymuconolactone decarboxylase family 8 88 1.2E-21 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS16025 6b68b7b8f927d89802ee2ce745793bd9 142 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 24 73 7.6E-20 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SMD11_RS16025 6b68b7b8f927d89802ee2ce745793bd9 142 Gene3D G3DSA:1.20.1290.10 2 140 7.6E-51 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 SMD11_RS34460 90391eca0b1fbdda1ca84d03dc9f6a20 70 Pfam PF13546 DDE superfamily endonuclease 8 70 2.0E-7 T 06-07-2017 SMD11_RS29570 139f31bbcd1e2e63b91e3ff753f5186d 188 SUPERFAMILY SSF55729 5 171 1.78E-26 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS29570 139f31bbcd1e2e63b91e3ff753f5186d 188 Gene3D G3DSA:3.40.630.30 6 177 4.1E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS29570 139f31bbcd1e2e63b91e3ff753f5186d 188 Pfam PF13302 Acetyltransferase (GNAT) domain 12 148 1.0E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS03240 ea13486bfc87ed85d94399303739bcd7 361 Gene3D G3DSA:3.40.640.10 16 268 2.3E-62 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS03240 ea13486bfc87ed85d94399303739bcd7 361 Gene3D G3DSA:3.90.1150.10 270 356 2.9E-26 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS03240 ea13486bfc87ed85d94399303739bcd7 361 SUPERFAMILY SSF53383 21 357 4.87E-93 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS03240 ea13486bfc87ed85d94399303739bcd7 361 Pfam PF01212 Beta-eliminating lyase 23 308 6.5E-59 T 06-07-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 SMD11_RS15305 08f21394782aae8f8f8c06b22fa769ad 819 Gene3D G3DSA:3.40.50.300 79 279 1.4E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15305 08f21394782aae8f8f8c06b22fa769ad 819 Pfam PF00270 DEAD/DEAH box helicase 99 274 7.0E-24 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SMD11_RS15305 08f21394782aae8f8f8c06b22fa769ad 819 Gene3D G3DSA:3.40.50.300 328 485 1.7E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15305 08f21394782aae8f8f8c06b22fa769ad 819 SUPERFAMILY SSF52540 105 275 8.46E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15305 08f21394782aae8f8f8c06b22fa769ad 819 SUPERFAMILY SSF52540 306 452 8.46E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15305 08f21394782aae8f8f8c06b22fa769ad 819 SMART SM00490 361 442 4.4E-16 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS15305 08f21394782aae8f8f8c06b22fa769ad 819 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 60 808 0.0 T 06-07-2017 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria SMD11_RS15305 08f21394782aae8f8f8c06b22fa769ad 819 Pfam PF00271 Helicase conserved C-terminal domain 332 442 1.5E-10 T 06-07-2017 IPR001650 Helicase, C-terminal SMD11_RS15305 08f21394782aae8f8f8c06b22fa769ad 819 Pfam PF09369 Domain of unknown function (DUF1998) 703 782 4.9E-19 T 06-07-2017 IPR018973 DEAD/DEAH-box helicase, putative SMD11_RS15305 08f21394782aae8f8f8c06b22fa769ad 819 SMART SM00487 92 301 4.6E-30 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain SMD11_RS21020 c412db96419183566022bc175953f76d 198 Pfam PF02622 Uncharacterized ACR, COG1678 16 181 3.4E-35 T 06-07-2017 IPR003774 Protein of unknown function UPF0301 SMD11_RS21020 c412db96419183566022bc175953f76d 198 SUPERFAMILY SSF143456 4 192 2.62E-44 T 06-07-2017 SMD11_RS21020 c412db96419183566022bc175953f76d 198 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 5 195 26.0 T 06-07-2017 IPR003774 Protein of unknown function UPF0301 SMD11_RS21020 c412db96419183566022bc175953f76d 198 Gene3D G3DSA:3.40.1740.10 139 184 4.3E-28 T 06-07-2017 SMD11_RS21020 c412db96419183566022bc175953f76d 198 Gene3D G3DSA:3.40.1740.10 2 44 4.3E-28 T 06-07-2017 SMD11_RS03750 901144bb2b056e3fb3c0104e4d1721c2 412 Gene3D G3DSA:3.20.20.80 18 317 4.0E-20 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS03750 901144bb2b056e3fb3c0104e4d1721c2 412 SUPERFAMILY SSF51445 5 333 1.34E-34 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS31140 2e206e2cdb08b5919724869664cd7359 370 Gene3D G3DSA:3.50.50.60 2 175 4.4E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31140 2e206e2cdb08b5919724869664cd7359 370 Gene3D G3DSA:3.50.50.60 270 348 4.4E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31140 2e206e2cdb08b5919724869664cd7359 370 Pfam PF01494 FAD binding domain 3 338 2.1E-24 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS31140 2e206e2cdb08b5919724869664cd7359 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 3.0E-17 T 06-07-2017 SMD11_RS31140 2e206e2cdb08b5919724869664cd7359 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 3.0E-17 T 06-07-2017 SMD11_RS31140 2e206e2cdb08b5919724869664cd7359 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 3.0E-17 T 06-07-2017 SMD11_RS31140 2e206e2cdb08b5919724869664cd7359 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 3.0E-17 T 06-07-2017 SMD11_RS31140 2e206e2cdb08b5919724869664cd7359 370 SUPERFAMILY SSF51905 3 170 1.18E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31140 2e206e2cdb08b5919724869664cd7359 370 SUPERFAMILY SSF51905 269 349 1.18E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS14360 6323a7e93150e9a5afd2bf0c4d4316dd 760 Gene3D G3DSA:1.25.40.10 710 732 8.4E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS14360 6323a7e93150e9a5afd2bf0c4d4316dd 760 Gene3D G3DSA:1.25.40.10 522 566 8.4E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS14360 6323a7e93150e9a5afd2bf0c4d4316dd 760 Gene3D G3DSA:1.25.40.10 432 475 8.4E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS14360 6323a7e93150e9a5afd2bf0c4d4316dd 760 Gene3D G3DSA:1.25.40.10 621 655 8.4E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS14360 6323a7e93150e9a5afd2bf0c4d4316dd 760 SUPERFAMILY SSF89372 4 183 4.18E-12 T 06-07-2017 SMD11_RS14360 6323a7e93150e9a5afd2bf0c4d4316dd 760 SUPERFAMILY SSF89372 145 356 7.19E-19 T 06-07-2017 SMD11_RS14360 6323a7e93150e9a5afd2bf0c4d4316dd 760 Gene3D G3DSA:2.120.10.70 129 360 7.5E-11 T 06-07-2017 SMD11_RS06350 e6f958a76e228b20c1d640d0c0acbc7e 241 SUPERFAMILY SSF56214 141 239 2.44E-18 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS06350 e6f958a76e228b20c1d640d0c0acbc7e 241 Gene3D G3DSA:3.90.470.20 44 151 5.8E-23 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS06350 e6f958a76e228b20c1d640d0c0acbc7e 241 Gene3D G3DSA:3.90.470.20 152 237 5.0E-15 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS06350 e6f958a76e228b20c1d640d0c0acbc7e 241 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 141 202 1.9E-10 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS06350 e6f958a76e228b20c1d640d0c0acbc7e 241 SUPERFAMILY SSF56214 44 134 3.84E-16 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SMD11_RS06000 753dc38db7d92ba9430df4ff989f930c 110 Pfam PF01844 HNH endonuclease 63 103 2.0E-10 T 06-07-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 SMD11_RS06000 753dc38db7d92ba9430df4ff989f930c 110 SMART SM00507 50 100 2.4E-10 T 06-07-2017 IPR003615 HNH nuclease SMD11_RS11325 9f04603078911ee03e6d563394063818 421 Gene3D G3DSA:1.25.40.10 196 371 2.6E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS11325 9f04603078911ee03e6d563394063818 421 SUPERFAMILY SSF48452 196 371 1.17E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS11325 9f04603078911ee03e6d563394063818 421 Gene3D G3DSA:1.10.260.40 6 74 4.2E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS28675 a1b10636b32a0ed12979891956191f80 138 Gene3D G3DSA:3.10.180.10 14 135 1.3E-13 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS28675 a1b10636b32a0ed12979891956191f80 138 SUPERFAMILY SSF54593 11 134 8.32E-14 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS17475 53d299772d386edb54cc9efae8669f27 417 Pfam PF12642 Conjugative transposon protein TcpC 160 408 2.5E-18 T 06-07-2017 IPR024735 Conjugative transposon protein TcpC SMD11_RS33245 2d3762f7aed212f70f2bdf2c94b71cbb 148 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 136 4.8E-22 T 06-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain SMD11_RS33245 2d3762f7aed212f70f2bdf2c94b71cbb 148 SUPERFAMILY SSF55961 1 145 1.46E-27 T 06-07-2017 SMD11_RS33245 2d3762f7aed212f70f2bdf2c94b71cbb 148 Gene3D G3DSA:3.30.530.20 1 147 1.8E-20 T 06-07-2017 IPR023393 START-like domain SMD11_RS21195 04b13f73eb4334eeef4a336f4207b82a 197 Pfam PF00857 Isochorismatase family 4 188 2.6E-34 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS21195 04b13f73eb4334eeef4a336f4207b82a 197 Gene3D G3DSA:3.40.50.850 1 188 6.4E-58 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS21195 04b13f73eb4334eeef4a336f4207b82a 197 SUPERFAMILY SSF52499 2 188 4.58E-48 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS31080 4317e6f0718bc379c3a345648285ed89 500 SUPERFAMILY SSF52091 412 487 2.94E-11 T 06-07-2017 IPR002645 STAS domain SMD11_RS31080 4317e6f0718bc379c3a345648285ed89 500 Pfam PF00916 Sulfate permease family 176 368 1.4E-27 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 SMD11_RS31080 4317e6f0718bc379c3a345648285ed89 500 Pfam PF00916 Sulfate permease family 25 151 1.0E-18 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 SMD11_RS31080 4317e6f0718bc379c3a345648285ed89 500 Gene3D G3DSA:3.30.750.24 412 484 2.1E-8 T 06-07-2017 IPR002645 STAS domain SMD11_RS31080 4317e6f0718bc379c3a345648285ed89 500 Pfam PF01740 STAS domain 415 484 5.7E-5 T 06-07-2017 IPR002645 STAS domain SMD11_RS19515 9c48d8a088492ed05bb88b62cdd2eb52 286 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 266 2.6E-62 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted SMD11_RS19515 9c48d8a088492ed05bb88b62cdd2eb52 286 Pfam PF00296 Luciferase-like monooxygenase 17 250 9.2E-43 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS19515 9c48d8a088492ed05bb88b62cdd2eb52 286 SUPERFAMILY SSF51679 17 284 4.88E-49 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS19515 9c48d8a088492ed05bb88b62cdd2eb52 286 Gene3D G3DSA:3.20.20.30 17 247 1.7E-53 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS10980 f29fddfbf8ebebaf18036d9f9a0bc20e 298 SUPERFAMILY SSF51445 92 297 1.19E-64 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS10980 f29fddfbf8ebebaf18036d9f9a0bc20e 298 Pfam PF01183 Glycosyl hydrolases family 25 96 280 1.1E-51 T 06-07-2017 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 SMD11_RS10980 f29fddfbf8ebebaf18036d9f9a0bc20e 298 SMART SM00641 93 202 9.7E-48 T 06-07-2017 IPR018077 Glycoside hydrolase, family 25 subgroup SMD11_RS10980 f29fddfbf8ebebaf18036d9f9a0bc20e 298 Gene3D G3DSA:3.20.20.80 93 297 9.3E-73 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS13655 decb0778deb637ea58c0b9090eaf1a4f 598 Gene3D G3DSA:3.30.200.20 9 128 2.7E-23 T 06-07-2017 SMD11_RS13655 decb0778deb637ea58c0b9090eaf1a4f 598 SUPERFAMILY SSF56112 10 280 1.24E-71 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS13655 decb0778deb637ea58c0b9090eaf1a4f 598 SUPERFAMILY SSF56112 484 538 1.24E-71 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS13655 decb0778deb637ea58c0b9090eaf1a4f 598 Gene3D G3DSA:1.10.510.10 129 278 1.3E-44 T 06-07-2017 SMD11_RS13655 decb0778deb637ea58c0b9090eaf1a4f 598 Gene3D G3DSA:1.10.510.10 369 384 1.3E-44 T 06-07-2017 SMD11_RS13655 decb0778deb637ea58c0b9090eaf1a4f 598 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 136 148 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS13655 decb0778deb637ea58c0b9090eaf1a4f 598 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 19 42 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS13655 decb0778deb637ea58c0b9090eaf1a4f 598 Pfam PF00069 Protein kinase domain 13 268 5.4E-43 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS13655 decb0778deb637ea58c0b9090eaf1a4f 598 SMART SM00220 13 594 6.9E-53 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS13755 592f27a058cadfc9b626e499d3bf13bb 461 Gene3D G3DSA:1.20.1250.20 250 422 1.5E-14 T 06-07-2017 SMD11_RS13755 592f27a058cadfc9b626e499d3bf13bb 461 Gene3D G3DSA:1.20.1250.20 57 231 2.2E-18 T 06-07-2017 SMD11_RS13755 592f27a058cadfc9b626e499d3bf13bb 461 Pfam PF05977 Transmembrane secretion effector 34 422 3.5E-55 T 06-07-2017 IPR010290 Transmembrane secretion effector SMD11_RS13755 592f27a058cadfc9b626e499d3bf13bb 461 SUPERFAMILY SSF103473 42 420 3.14E-48 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS28990 07704eda63388d40b2e353ed15282e3d 222 SUPERFAMILY SSF46955 1 85 2.15E-12 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS28990 07704eda63388d40b2e353ed15282e3d 222 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 8.1E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS28990 07704eda63388d40b2e353ed15282e3d 222 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 8.1E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS28990 07704eda63388d40b2e353ed15282e3d 222 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 8.1E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS28990 07704eda63388d40b2e353ed15282e3d 222 SMART SM00422 1 71 0.0013 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS28990 07704eda63388d40b2e353ed15282e3d 222 Pfam PF13411 MerR HTH family regulatory protein 1 69 3.2E-14 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS28990 07704eda63388d40b2e353ed15282e3d 222 Gene3D G3DSA:1.10.1660.10 1 84 8.2E-16 T 06-07-2017 SMD11_RS10015 99b0599fb1b76666708b8843773f9ba4 64 SUPERFAMILY SSF54862 2 62 1.2E-11 T 06-07-2017 SMD11_RS10015 99b0599fb1b76666708b8843773f9ba4 64 Gene3D G3DSA:3.30.70.20 2 63 6.0E-15 T 06-07-2017 SMD11_RS10015 99b0599fb1b76666708b8843773f9ba4 64 Pfam PF13459 4Fe-4S single cluster domain 3 60 6.8E-13 T 06-07-2017 SMD11_RS10015 99b0599fb1b76666708b8843773f9ba4 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.3E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD11_RS10015 99b0599fb1b76666708b8843773f9ba4 64 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 1.3E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD11_RS10015 99b0599fb1b76666708b8843773f9ba4 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.3E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD11_RS07735 6c2413c15abf6a707df278d85f9a455e 189 SUPERFAMILY SSF54427 35 168 1.1E-35 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS07735 6c2413c15abf6a707df278d85f9a455e 189 Pfam PF07366 SnoaL-like polyketide cyclase 40 154 1.2E-32 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain SMD11_RS07735 6c2413c15abf6a707df278d85f9a455e 189 Gene3D G3DSA:3.10.450.50 35 167 8.0E-42 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS13660 6b0d4994f904178cb27976ea7ace465e 372 SUPERFAMILY SSF53383 17 371 1.26E-74 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS13660 6b0d4994f904178cb27976ea7ace465e 372 Pfam PF00266 Aminotransferase class-V 139 331 1.7E-16 T 06-07-2017 IPR000192 Aminotransferase class V domain SMD11_RS13660 6b0d4994f904178cb27976ea7ace465e 372 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 5 372 23.347 T 06-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 SMD11_RS13660 6b0d4994f904178cb27976ea7ace465e 372 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 11 372 6.4E-211 T 06-07-2017 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 SMD11_RS13660 6b0d4994f904178cb27976ea7ace465e 372 Gene3D G3DSA:3.40.640.10 20 266 3.5E-51 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS13660 6b0d4994f904178cb27976ea7ace465e 372 PIRSF PIRSF000525 1 372 4.3E-74 T 06-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 SMD11_RS01240 97563496ada57b62cc68911b0fdd20d6 347 Pfam PF14040 Deoxyribonuclease NucA/NucB 259 345 1.8E-15 T 06-07-2017 IPR029476 Deoxyribonuclease NucA/NucB SMD11_RS25190 b29cf97a6e4c010e7bc911ec961907b2 331 Pfam PF02628 Cytochrome oxidase assembly protein 24 295 9.5E-21 T 06-07-2017 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 SMD11_RS03470 a3f9f1d3b9e4deee30bed6328634d002 88 SMART SM00418 1 70 6.3E-4 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS03470 a3f9f1d3b9e4deee30bed6328634d002 88 Pfam PF01022 Bacterial regulatory protein, arsR family 2 44 2.4E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS03470 a3f9f1d3b9e4deee30bed6328634d002 88 SUPERFAMILY SSF46785 1 70 7.37E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03470 a3f9f1d3b9e4deee30bed6328634d002 88 Gene3D G3DSA:1.10.10.10 2 81 9.3E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS06315 9bf76758e4adf2994339b193d9190e57 191 Pfam PF13302 Acetyltransferase (GNAT) domain 19 160 2.1E-15 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS06315 9bf76758e4adf2994339b193d9190e57 191 Gene3D G3DSA:3.40.630.30 16 185 3.5E-36 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS06315 9bf76758e4adf2994339b193d9190e57 191 SUPERFAMILY SSF55729 16 184 4.75E-29 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS25995 b814990b0c8bedf2fa1a355a6b9acbb7 307 Gene3D G3DSA:2.40.10.10 118 204 6.1E-29 T 06-07-2017 SMD11_RS25995 b814990b0c8bedf2fa1a355a6b9acbb7 307 Pfam PF02983 Alpha-lytic protease prodomain 47 99 8.5E-10 T 06-07-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 SMD11_RS25995 b814990b0c8bedf2fa1a355a6b9acbb7 307 Gene3D G3DSA:2.40.10.10 205 294 2.5E-29 T 06-07-2017 SMD11_RS25995 b814990b0c8bedf2fa1a355a6b9acbb7 307 SUPERFAMILY SSF50494 126 300 2.24E-36 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS25995 b814990b0c8bedf2fa1a355a6b9acbb7 307 Gene3D G3DSA:3.30.300.50 46 112 1.1E-7 T 06-07-2017 SMD11_RS25995 b814990b0c8bedf2fa1a355a6b9acbb7 307 PIRSF PIRSF001134 15 307 6.2E-96 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS25995 b814990b0c8bedf2fa1a355a6b9acbb7 307 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 248 271 1.3E-46 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS25995 b814990b0c8bedf2fa1a355a6b9acbb7 307 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 272 286 1.3E-46 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS25995 b814990b0c8bedf2fa1a355a6b9acbb7 307 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 228 245 1.3E-46 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS25995 b814990b0c8bedf2fa1a355a6b9acbb7 307 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 144 158 1.3E-46 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS25995 b814990b0c8bedf2fa1a355a6b9acbb7 307 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 207 227 1.3E-46 T 06-07-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 SMD11_RS25995 b814990b0c8bedf2fa1a355a6b9acbb7 307 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 257 268 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site SMD11_RS25995 b814990b0c8bedf2fa1a355a6b9acbb7 307 Pfam PF00089 Trypsin 118 296 2.1E-9 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD11_RS31570 ec12352e7abab544a284249ca572953e 378 Pfam PF00583 Acetyltransferase (GNAT) family 61 134 1.2E-5 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS31570 ec12352e7abab544a284249ca572953e 378 SUPERFAMILY SSF55729 1 141 6.03E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS31570 ec12352e7abab544a284249ca572953e 378 Gene3D G3DSA:3.40.630.30 1 146 1.0E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS20380 38f9b9166b6442869054baff17396338 343 Gene3D G3DSA:3.20.20.30 1 340 6.8E-72 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS20380 38f9b9166b6442869054baff17396338 343 Pfam PF00296 Luciferase-like monooxygenase 15 323 7.9E-73 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS20380 38f9b9166b6442869054baff17396338 343 SUPERFAMILY SSF51679 1 335 1.22E-62 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS20380 38f9b9166b6442869054baff17396338 343 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 3 327 2.5E-141 T 06-07-2017 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c SMD11_RS14715 7bbae596ea3587d611ff1427a1f82d12 282 ProDom PD040376 SCO3349 RV0495C/MT0515 ML2435 MB0506C CGL0407 38 280 8.0E-125 T 06-07-2017 SMD11_RS05420 26e3026cc1711bb44e224f36b4c21001 206 SUPERFAMILY SSF52317 2 183 1.03E-45 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS05420 26e3026cc1711bb44e224f36b4c21001 206 Pfam PF01965 DJ-1/PfpI family 2 162 1.6E-27 T 06-07-2017 IPR002818 DJ-1/PfpI SMD11_RS05420 26e3026cc1711bb44e224f36b4c21001 206 Gene3D G3DSA:3.40.50.880 2 203 1.5E-64 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS11095 5cb0f1c59debb3436dbdfe3503bc9326 323 SUPERFAMILY SSF53850 20 308 1.71E-51 T 06-07-2017 SMD11_RS11095 5cb0f1c59debb3436dbdfe3503bc9326 323 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 71 308 5.8E-58 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD11_RS11095 5cb0f1c59debb3436dbdfe3503bc9326 323 Gene3D G3DSA:3.40.190.10 272 308 2.4E-30 T 06-07-2017 SMD11_RS11095 5cb0f1c59debb3436dbdfe3503bc9326 323 Gene3D G3DSA:3.40.190.10 67 166 2.4E-30 T 06-07-2017 SMD11_RS11095 5cb0f1c59debb3436dbdfe3503bc9326 323 Gene3D G3DSA:3.40.190.10 170 271 2.8E-21 T 06-07-2017 SMD11_RS11095 5cb0f1c59debb3436dbdfe3503bc9326 323 SMART SM00062 70 311 4.3E-48 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SMD11_RS24165 91d8dcac4dc040da78409eb45adc1795 118 SUPERFAMILY SSF89360 14 108 8.83E-28 T 06-07-2017 IPR000361 FeS cluster biogenesis SMD11_RS24165 91d8dcac4dc040da78409eb45adc1795 118 Pfam PF01521 Iron-sulphur cluster biosynthesis 14 115 1.3E-19 T 06-07-2017 IPR000361 FeS cluster biogenesis SMD11_RS24165 91d8dcac4dc040da78409eb45adc1795 118 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 14 118 2.1E-36 T 06-07-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 SMD11_RS24165 91d8dcac4dc040da78409eb45adc1795 118 Gene3D G3DSA:2.60.300.12 14 108 6.8E-29 T 06-07-2017 IPR000361 FeS cluster biogenesis SMD11_RS24165 91d8dcac4dc040da78409eb45adc1795 118 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 100 117 - T 06-07-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site SMD11_RS30100 10979c4b14260b2a22473ab0b853ba9d 129 Pfam PF03995 Peptidase inhibitor family I36 39 100 3.1E-7 T 06-07-2017 SMD11_RS33240 800171de66b6879178e08c0779506446 338 Gene3D G3DSA:3.40.50.720 6 222 3.6E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33240 800171de66b6879178e08c0779506446 338 SUPERFAMILY SSF51735 5 255 3.11E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33240 800171de66b6879178e08c0779506446 338 Pfam PF07993 Male sterility protein 63 202 2.5E-16 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 SMD11_RS14950 59c9069a98ab117b69ede58e2c0c69f4 201 SUPERFAMILY SSF55620 6 198 2.67E-77 T 06-07-2017 SMD11_RS14950 59c9069a98ab117b69ede58e2c0c69f4 201 Gene3D G3DSA:3.30.1130.10 70 199 1.7E-59 T 06-07-2017 SMD11_RS14950 59c9069a98ab117b69ede58e2c0c69f4 201 Gene3D G3DSA:1.10.286.10 16 67 8.8E-25 T 06-07-2017 SMD11_RS14950 59c9069a98ab117b69ede58e2c0c69f4 201 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 127 137 - T 06-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 SMD11_RS14950 59c9069a98ab117b69ede58e2c0c69f4 201 Pfam PF01227 GTP cyclohydrolase I 22 198 4.9E-77 T 06-07-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 SMD11_RS14950 59c9069a98ab117b69ede58e2c0c69f4 201 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 22 198 5.3E-73 T 06-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 SMD11_RS14950 59c9069a98ab117b69ede58e2c0c69f4 201 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 17 199 42.265 T 06-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 SMD11_RS14950 59c9069a98ab117b69ede58e2c0c69f4 201 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 77 93 - T 06-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 SMD11_RS09335 886a6f5c25b4c9387a75986b1a8c4f2c 290 SUPERFAMILY SSF48317 80 277 6.54E-22 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS09335 886a6f5c25b4c9387a75986b1a8c4f2c 290 Gene3D G3DSA:1.20.144.10 88 275 2.8E-23 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS09335 886a6f5c25b4c9387a75986b1a8c4f2c 290 SMART SM00014 162 275 3.1E-4 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS09335 886a6f5c25b4c9387a75986b1a8c4f2c 290 Pfam PF01569 PAP2 superfamily 163 274 6.3E-14 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS31235 5e16a49665f4c90792cb3a525af6f581 565 Gene3D G3DSA:3.40.50.300 346 559 4.7E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31235 5e16a49665f4c90792cb3a525af6f581 565 Pfam PF00664 ABC transporter transmembrane region 29 293 1.8E-24 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS31235 5e16a49665f4c90792cb3a525af6f581 565 SUPERFAMILY SSF90123 12 321 1.15E-54 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SMD11_RS31235 5e16a49665f4c90792cb3a525af6f581 565 ProSitePatterns PS00211 ABC transporters family signature. 468 482 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS31235 5e16a49665f4c90792cb3a525af6f581 565 Pfam PF00005 ABC transporter 348 495 3.9E-14 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS31235 5e16a49665f4c90792cb3a525af6f581 565 Gene3D G3DSA:1.20.1560.10 12 321 3.1E-50 T 06-07-2017 SMD11_RS31235 5e16a49665f4c90792cb3a525af6f581 565 SUPERFAMILY SSF52540 339 562 6.22E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10740 a4e57468087ffda6ddc87d8b00015fb5 107 SUPERFAMILY SSF52091 2 97 7.65E-21 T 06-07-2017 IPR002645 STAS domain SMD11_RS10740 a4e57468087ffda6ddc87d8b00015fb5 107 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 96 1.2E-16 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMD11_RS10740 a4e57468087ffda6ddc87d8b00015fb5 107 Pfam PF13466 STAS domain 10 89 1.5E-14 T 06-07-2017 IPR002645 STAS domain SMD11_RS10740 a4e57468087ffda6ddc87d8b00015fb5 107 Gene3D G3DSA:3.30.750.24 2 98 6.5E-25 T 06-07-2017 IPR002645 STAS domain SMD11_RS21810 9bd09e8585bcc25970fa4ff793fff813 385 Gene3D G3DSA:3.30.360.10 162 376 1.6E-35 T 06-07-2017 SMD11_RS21810 9bd09e8585bcc25970fa4ff793fff813 385 SUPERFAMILY SSF51735 7 176 8.92E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS21810 9bd09e8585bcc25970fa4ff793fff813 385 SUPERFAMILY SSF55347 149 337 3.92E-28 T 06-07-2017 SMD11_RS21810 9bd09e8585bcc25970fa4ff793fff813 385 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 53 141 9.0E-7 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD11_RS21810 9bd09e8585bcc25970fa4ff793fff813 385 Gene3D G3DSA:3.40.50.720 7 161 4.1E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05350 fa834a9f847374ac4f918fc721b7538a 270 SMART SM00382 76 259 6.3E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS05350 fa834a9f847374ac4f918fc721b7538a 270 SUPERFAMILY SSF52540 62 263 9.69E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05350 fa834a9f847374ac4f918fc721b7538a 270 Pfam PF00005 ABC transporter 68 201 1.3E-16 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS05350 fa834a9f847374ac4f918fc721b7538a 270 Gene3D G3DSA:3.40.50.300 62 268 1.7E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05350 fa834a9f847374ac4f918fc721b7538a 270 ProSitePatterns PS00211 ABC transporters family signature. 174 188 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS31575 a2eaf7ddc3b8f4567a56422ab0baa0aa 385 Pfam PF04443 Acyl-protein synthetase, LuxE 74 378 3.1E-25 T 06-07-2017 IPR007534 Acyl-protein synthetase, LuxE GO:0008218|GO:0047474 MetaCyc: PWY-7723 SMD11_RS11555 7d3a363e6d1cabba071a4bcfd1ce2d51 454 Pfam PF03109 ABC1 family 113 227 1.2E-30 T 06-07-2017 IPR004147 UbiB domain SMD11_RS11555 7d3a363e6d1cabba071a4bcfd1ce2d51 454 SUPERFAMILY SSF56112 195 331 8.51E-23 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS11555 7d3a363e6d1cabba071a4bcfd1ce2d51 454 SUPERFAMILY SSF56112 95 158 8.51E-23 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS30975 d66068e673ad31d23ea9b3f0070f2fc3 67 SUPERFAMILY SSF50249 1 66 9.3E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS30975 d66068e673ad31d23ea9b3f0070f2fc3 67 SMART SM00357 3 67 1.4E-30 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 SMD11_RS30975 d66068e673ad31d23ea9b3f0070f2fc3 67 PIRSF PIRSF002599 1 67 6.4E-26 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 SMD11_RS30975 d66068e673ad31d23ea9b3f0070f2fc3 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.2E-31 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS30975 d66068e673ad31d23ea9b3f0070f2fc3 67 PRINTS PR00050 Cold shock protein signature 25 34 7.7E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS30975 d66068e673ad31d23ea9b3f0070f2fc3 67 PRINTS PR00050 Cold shock protein signature 40 58 7.7E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS30975 d66068e673ad31d23ea9b3f0070f2fc3 67 PRINTS PR00050 Cold shock protein signature 4 19 7.7E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SMD11_RS30975 d66068e673ad31d23ea9b3f0070f2fc3 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site SMD11_RS30975 d66068e673ad31d23ea9b3f0070f2fc3 67 Gene3D G3DSA:2.40.50.140 1 65 1.0E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS01260 379372247b6a73a8b4f238ad82820627 544 SMART SM00382 30 215 1.1E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS01260 379372247b6a73a8b4f238ad82820627 544 SMART SM00382 367 533 6.4E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS01260 379372247b6a73a8b4f238ad82820627 544 SUPERFAMILY SSF52540 347 543 2.92E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01260 379372247b6a73a8b4f238ad82820627 544 SUPERFAMILY SSF52540 9 216 3.74E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01260 379372247b6a73a8b4f238ad82820627 544 Pfam PF12848 ABC transporter 209 271 2.7E-6 T 06-07-2017 IPR032781 ABC-transporter extension domain SMD11_RS01260 379372247b6a73a8b4f238ad82820627 544 Pfam PF00005 ABC transporter 24 171 1.2E-18 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS01260 379372247b6a73a8b4f238ad82820627 544 Pfam PF00005 ABC transporter 360 489 9.4E-19 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS01260 379372247b6a73a8b4f238ad82820627 544 Gene3D G3DSA:3.40.50.300 6 253 6.6E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01260 379372247b6a73a8b4f238ad82820627 544 Gene3D G3DSA:3.40.50.300 344 543 5.2E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS15595 35f083c10cbcadb10c813d22f69743f3 300 Pfam PF02104 SURF1 family 20 231 8.1E-24 T 06-07-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS11255 31ec3ef082f1df61ff186ad5b557a098 489 SUPERFAMILY SSF55874 345 484 6.42E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS11255 31ec3ef082f1df61ff186ad5b557a098 489 Gene3D G3DSA:3.30.565.10 345 486 2.4E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS11255 31ec3ef082f1df61ff186ad5b557a098 489 SUPERFAMILY SSF55785 173 281 8.19E-7 T 06-07-2017 IPR000014 PAS domain SMD11_RS11255 31ec3ef082f1df61ff186ad5b557a098 489 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 385 484 2.7E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS11255 31ec3ef082f1df61ff186ad5b557a098 489 Pfam PF12282 Signal transduction histidine kinase 1 144 1.1E-59 T 06-07-2017 IPR022066 Signal transduction histidine kinase SMD11_RS11255 31ec3ef082f1df61ff186ad5b557a098 489 Pfam PF08448 PAS fold 172 276 2.2E-12 T 06-07-2017 IPR013656 PAS fold-4 SMD11_RS11255 31ec3ef082f1df61ff186ad5b557a098 489 Pfam PF07568 Histidine kinase 290 360 1.4E-22 T 06-07-2017 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain SMD11_RS11255 31ec3ef082f1df61ff186ad5b557a098 489 SMART SM00387 382 486 2.7E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS11255 31ec3ef082f1df61ff186ad5b557a098 489 Gene3D G3DSA:3.30.450.20 173 281 2.0E-6 T 06-07-2017 SMD11_RS11255 31ec3ef082f1df61ff186ad5b557a098 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 483 1.4E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS11255 31ec3ef082f1df61ff186ad5b557a098 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 440 1.4E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS11255 31ec3ef082f1df61ff186ad5b557a098 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 463 1.4E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SMD11_RS00295 feef4afcec43250ad58ae6109ff02628 95 Gene3D G3DSA:1.10.260.40 13 70 2.0E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS00295 feef4afcec43250ad58ae6109ff02628 95 SUPERFAMILY SSF47413 6 63 1.3E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS24870 7c0d920d56555a518684340198c59f33 184 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 170 11.022 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SMD11_RS24870 7c0d920d56555a518684340198c59f33 184 SUPERFAMILY SSF81573 76 134 4.18E-8 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMD11_RS24870 7c0d920d56555a518684340198c59f33 184 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 25 170 5.5E-20 T 06-07-2017 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 SMD11_RS24870 7c0d920d56555a518684340198c59f33 184 Gene3D G3DSA:1.20.5.620 76 135 6.7E-10 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMD11_RS24870 7c0d920d56555a518684340198c59f33 184 Pfam PF00430 ATP synthase B/B' CF(0) 21 148 3.9E-21 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SMD11_RS08155 6d2db76c3dd630626f9dabab5ed52d3b 410 Gene3D G3DSA:3.40.50.150 93 247 6.9E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS08155 6d2db76c3dd630626f9dabab5ed52d3b 410 Pfam PF08484 C-methyltransferase C-terminal domain 247 405 3.1E-44 T 06-07-2017 IPR013691 C-methyltransferase SMD11_RS08155 6d2db76c3dd630626f9dabab5ed52d3b 410 Pfam PF13489 Methyltransferase domain 89 240 4.9E-11 T 06-07-2017 SMD11_RS08155 6d2db76c3dd630626f9dabab5ed52d3b 410 Pfam PF08421 Putative zinc binding domain 6 67 3.7E-17 T 06-07-2017 IPR013630 Methyltransferase putative zinc binding domain SMD11_RS08155 6d2db76c3dd630626f9dabab5ed52d3b 410 SUPERFAMILY SSF53335 88 248 1.17E-15 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS05770 d944da5bbb67f12092a400f30527188f 628 Gene3D G3DSA:2.60.120.200 426 600 4.3E-15 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain SMD11_RS05770 d944da5bbb67f12092a400f30527188f 628 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 436 598 1.2E-12 T 06-07-2017 SMD11_RS05770 d944da5bbb67f12092a400f30527188f 628 SUPERFAMILY SSF50939 39 387 1.26E-77 T 06-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMD11_RS05770 d944da5bbb67f12092a400f30527188f 628 Pfam PF13088 BNR repeat-like domain 56 338 9.9E-31 T 06-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMD11_RS05770 d944da5bbb67f12092a400f30527188f 628 Gene3D G3DSA:2.120.10.10 39 387 2.7E-79 T 06-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMD11_RS05770 d944da5bbb67f12092a400f30527188f 628 SUPERFAMILY SSF49899 420 600 1.12E-21 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain SMD11_RS13060 097de05adacd47421bc55b1a98b5bcf5 126 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 6 111 4.1E-29 T 06-07-2017 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS13060 097de05adacd47421bc55b1a98b5bcf5 126 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 5 108 1.0E-23 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 SMD11_RS13060 097de05adacd47421bc55b1a98b5bcf5 126 Gene3D G3DSA:1.20.1300.10 3 113 1.1E-29 T 06-07-2017 SMD11_RS13060 097de05adacd47421bc55b1a98b5bcf5 126 SUPERFAMILY SSF81343 2 113 4.14E-27 T 06-07-2017 SMD11_RS25135 37e51e02319bd4101ca148a416802f77 78 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 3.1E-6 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMD11_RS25135 37e51e02319bd4101ca148a416802f77 78 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 3.1E-6 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMD11_RS25135 37e51e02319bd4101ca148a416802f77 78 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 3.1E-6 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMD11_RS25135 37e51e02319bd4101ca148a416802f77 78 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 3.1E-6 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMD11_RS25135 37e51e02319bd4101ca148a416802f77 78 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 5 73 8.2E-21 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMD11_RS25135 37e51e02319bd4101ca148a416802f77 78 Pfam PF03840 Preprotein translocase SecG subunit 5 73 2.2E-19 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SMD11_RS30325 8ce0cd21f74f23c0130e352c90ff5b42 489 Gene3D G3DSA:1.50.10.20 261 418 2.5E-11 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS30325 8ce0cd21f74f23c0130e352c90ff5b42 489 SUPERFAMILY SSF48239 325 429 3.73E-11 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS30325 8ce0cd21f74f23c0130e352c90ff5b42 489 SUPERFAMILY SSF48239 5 100 3.73E-11 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid SMD11_RS12610 0f4da1a98e2203595c0c41021802ddf5 494 Pfam PF00916 Sulfate permease family 10 376 1.9E-54 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 SMD11_RS03040 9a48c155dca506effb4a1f9e686ec87f 378 Gene3D G3DSA:3.20.20.70 6 369 1.9E-104 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS03040 9a48c155dca506effb4a1f9e686ec87f 378 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 18 346 4.9E-64 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMD11_RS03040 9a48c155dca506effb4a1f9e686ec87f 378 SUPERFAMILY SSF51395 10 369 1.37E-98 T 06-07-2017 SMD11_RS11545 94ecc434cd6328f6b105af54748f6159 198 Pfam PF01863 Protein of unknown function DUF45 105 180 9.5E-23 T 06-07-2017 IPR002725 Protein of unknown function DUF45 SMD11_RS01080 749255b74501e1c7fea2dbe756fb7d9b 190 Pfam PF13302 Acetyltransferase (GNAT) domain 13 154 1.8E-20 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS01080 749255b74501e1c7fea2dbe756fb7d9b 190 SUPERFAMILY SSF55729 7 155 3.48E-29 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS01080 749255b74501e1c7fea2dbe756fb7d9b 190 Gene3D G3DSA:3.40.630.30 5 159 7.5E-33 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS18970 60dd6e3b962f43501763c07d0d5c7539 127 SUPERFAMILY SSF53137 14 125 3.49E-47 T 06-07-2017 SMD11_RS18970 60dd6e3b962f43501763c07d0d5c7539 127 Gene3D G3DSA:3.30.420.100 31 127 9.6E-39 T 06-07-2017 SMD11_RS18970 60dd6e3b962f43501763c07d0d5c7539 127 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 14 127 4.4E-40 T 06-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18970 60dd6e3b962f43501763c07d0d5c7539 127 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 13 127 9.5E-50 T 06-07-2017 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS18970 60dd6e3b962f43501763c07d0d5c7539 127 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 13 127 26.841 T 06-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS00360 57a769b2ffa440de44a801a31175077f 130 Pfam PF03551 Transcriptional regulator PadR-like family 28 100 3.0E-23 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal SMD11_RS00360 57a769b2ffa440de44a801a31175077f 130 Gene3D G3DSA:1.10.10.10 13 118 2.4E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS00360 57a769b2ffa440de44a801a31175077f 130 SUPERFAMILY SSF46785 17 119 1.91E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04545 1417c8d99c80b407eb39c9182405b0a1 335 Pfam PF01497 Periplasmic binding protein 75 307 7.0E-26 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD11_RS04545 1417c8d99c80b407eb39c9182405b0a1 335 Gene3D G3DSA:3.40.50.1980 184 331 4.9E-34 T 06-07-2017 SMD11_RS04545 1417c8d99c80b407eb39c9182405b0a1 335 SUPERFAMILY SSF53807 56 328 9.81E-55 T 06-07-2017 SMD11_RS04545 1417c8d99c80b407eb39c9182405b0a1 335 Gene3D G3DSA:3.40.50.1980 55 181 2.4E-30 T 06-07-2017 SMD11_RS02890 c32eb8c9a7aa6125413581b3c2f440e4 480 SUPERFAMILY SSF48264 45 478 1.13E-95 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02890 c32eb8c9a7aa6125413581b3c2f440e4 480 Gene3D G3DSA:1.10.630.10 46 478 5.3E-102 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02890 c32eb8c9a7aa6125413581b3c2f440e4 480 Pfam PF00067 Cytochrome P450 49 464 2.4E-63 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02890 c32eb8c9a7aa6125413581b3c2f440e4 480 PRINTS PR00463 E-class P450 group I signature 68 87 1.1E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02890 c32eb8c9a7aa6125413581b3c2f440e4 480 PRINTS PR00463 E-class P450 group I signature 299 325 1.1E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02890 c32eb8c9a7aa6125413581b3c2f440e4 480 PRINTS PR00463 E-class P450 group I signature 381 405 1.1E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02890 c32eb8c9a7aa6125413581b3c2f440e4 480 PRINTS PR00463 E-class P450 group I signature 419 429 1.1E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02890 c32eb8c9a7aa6125413581b3c2f440e4 480 PRINTS PR00463 E-class P450 group I signature 279 296 1.1E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02890 c32eb8c9a7aa6125413581b3c2f440e4 480 PRINTS PR00463 E-class P450 group I signature 429 452 1.1E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02890 c32eb8c9a7aa6125413581b3c2f440e4 480 PRINTS PR00385 P450 superfamily signature 342 353 9.4E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02890 c32eb8c9a7aa6125413581b3c2f440e4 480 PRINTS PR00385 P450 superfamily signature 290 307 9.4E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02890 c32eb8c9a7aa6125413581b3c2f440e4 480 PRINTS PR00385 P450 superfamily signature 420 429 9.4E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02890 c32eb8c9a7aa6125413581b3c2f440e4 480 PRINTS PR00385 P450 superfamily signature 429 440 9.4E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS02890 c32eb8c9a7aa6125413581b3c2f440e4 480 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 422 431 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS22780 579978b958e3ccf226966e5bc5e3cb82 490 Pfam PF07690 Major Facilitator Superfamily 42 434 2.5E-53 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS22780 579978b958e3ccf226966e5bc5e3cb82 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 100 122 5.5E-7 T 06-07-2017 SMD11_RS22780 579978b958e3ccf226966e5bc5e3cb82 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 40 64 5.5E-7 T 06-07-2017 SMD11_RS22780 579978b958e3ccf226966e5bc5e3cb82 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 162 186 5.5E-7 T 06-07-2017 SMD11_RS22780 579978b958e3ccf226966e5bc5e3cb82 490 Gene3D G3DSA:1.20.1250.20 286 488 2.6E-14 T 06-07-2017 SMD11_RS22780 579978b958e3ccf226966e5bc5e3cb82 490 Gene3D G3DSA:1.20.1250.20 36 215 2.7E-28 T 06-07-2017 SMD11_RS22780 579978b958e3ccf226966e5bc5e3cb82 490 SUPERFAMILY SSF103473 26 221 7.85E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS22780 579978b958e3ccf226966e5bc5e3cb82 490 SUPERFAMILY SSF103473 272 488 7.85E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS14390 699679fd054a5a76ab24f74f45a08b83 91 SUPERFAMILY SSF54285 10 91 2.43E-11 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp SMD11_RS14390 699679fd054a5a76ab24f74f45a08b83 91 Pfam PF02597 ThiS family 12 91 7.6E-7 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 SMD11_RS14390 699679fd054a5a76ab24f74f45a08b83 91 Gene3D G3DSA:3.10.20.30 10 91 6.5E-11 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS10330 7a953b2f58461f8324dbb0781bc96d2e 179 SMART SM00644 33 163 1.2E-37 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS10330 7a953b2f58461f8324dbb0781bc96d2e 179 SUPERFAMILY SSF55846 33 175 1.03E-40 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS10330 7a953b2f58461f8324dbb0781bc96d2e 179 Gene3D G3DSA:3.40.80.10 34 175 1.6E-41 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS10330 7a953b2f58461f8324dbb0781bc96d2e 179 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 42 164 3.2E-23 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 SMD11_RS23660 a68a6775523df57b331c0e98e17c8340 546 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 508 542 0.0022 T 06-07-2017 IPR019931 LPXTG cell wall anchor domain SMD11_RS23660 a68a6775523df57b331c0e98e17c8340 546 Pfam PF04213 Htaa 63 228 5.7E-43 T 06-07-2017 IPR007331 Htaa SMD11_RS23660 a68a6775523df57b331c0e98e17c8340 546 Pfam PF04213 Htaa 314 473 9.7E-53 T 06-07-2017 IPR007331 Htaa SMD11_RS28950 1a5824e5f83fc7c5606ce8391009a839 526 Gene3D G3DSA:3.40.50.1820 199 324 5.5E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28950 1a5824e5f83fc7c5606ce8391009a839 526 Gene3D G3DSA:3.40.50.1820 70 155 5.5E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28950 1a5824e5f83fc7c5606ce8391009a839 526 Gene3D G3DSA:3.40.50.1820 382 500 5.5E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28950 1a5824e5f83fc7c5606ce8391009a839 526 Pfam PF08386 TAP-like protein 412 512 2.4E-27 T 06-07-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal SMD11_RS28950 1a5824e5f83fc7c5606ce8391009a839 526 SUPERFAMILY SSF53474 201 255 2.73E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28950 1a5824e5f83fc7c5606ce8391009a839 526 SUPERFAMILY SSF53474 102 156 2.73E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28950 1a5824e5f83fc7c5606ce8391009a839 526 SUPERFAMILY SSF53474 357 500 2.73E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32730 ff0f68673c9bf78acc019410402f6bf1 161 SMART SM00506 4 144 4.5E-14 T 06-07-2017 IPR002589 Macro domain SMD11_RS32730 ff0f68673c9bf78acc019410402f6bf1 161 SUPERFAMILY SSF52949 5 159 4.24E-37 T 06-07-2017 SMD11_RS06610 bb155276e659d8234cb8c3a0618398d6 351 Pfam PF03099 Biotin/lipoate A/B protein ligase family 159 265 9.6E-7 T 06-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 SMD11_RS06610 bb155276e659d8234cb8c3a0618398d6 351 SUPERFAMILY SSF55681 96 347 2.41E-68 T 06-07-2017 SMD11_RS06610 bb155276e659d8234cb8c3a0618398d6 351 Gene3D G3DSA:3.90.1550.10 94 347 1.2E-67 T 06-07-2017 SMD11_RS14905 fe9b4925ae392869e7e5278c1c46efc3 241 SUPERFAMILY SSF161098 24 205 3.79E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS14905 fe9b4925ae392869e7e5278c1c46efc3 241 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 220 7.7E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS14905 fe9b4925ae392869e7e5278c1c46efc3 241 Gene3D G3DSA:1.10.3720.10 19 210 5.1E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS08205 fac5dfd4153af481c8e1d82c33c0b19c 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 61 77 2.2E-5 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS08205 fac5dfd4153af481c8e1d82c33c0b19c 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 194 218 2.2E-5 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS08205 fac5dfd4153af481c8e1d82c33c0b19c 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 83 99 2.2E-5 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS08205 fac5dfd4153af481c8e1d82c33c0b19c 263 SUPERFAMILY SSF56655 9 249 4.84E-52 T 06-07-2017 SMD11_RS08205 fac5dfd4153af481c8e1d82c33c0b19c 263 Gene3D G3DSA:3.40.190.80 139 250 2.8E-27 T 06-07-2017 SMD11_RS08205 fac5dfd4153af481c8e1d82c33c0b19c 263 Pfam PF00459 Inositol monophosphatase family 43 232 1.9E-30 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS08205 fac5dfd4153af481c8e1d82c33c0b19c 263 Gene3D G3DSA:3.30.540.10 11 124 2.1E-23 T 06-07-2017 SMD11_RS01135 01be52680bf4098be2de2ee58883dce9 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 2.0E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS01135 01be52680bf4098be2de2ee58883dce9 230 SUPERFAMILY SSF46894 128 226 3.12E-26 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS01135 01be52680bf4098be2de2ee58883dce9 230 Gene3D G3DSA:1.10.10.10 127 227 1.4E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01135 01be52680bf4098be2de2ee58883dce9 230 Gene3D G3DSA:3.40.50.2300 2 121 8.7E-36 T 06-07-2017 SMD11_RS01135 01be52680bf4098be2de2ee58883dce9 230 SMART SM00448 1 112 9.3E-35 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS01135 01be52680bf4098be2de2ee58883dce9 230 SMART SM00862 150 225 2.0E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SMD11_RS01135 01be52680bf4098be2de2ee58883dce9 230 Pfam PF00072 Response regulator receiver domain 3 112 1.9E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS01135 01be52680bf4098be2de2ee58883dce9 230 SUPERFAMILY SSF52172 3 123 3.7E-36 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS08425 e518f9ad462483205f5f4b01f34c51c2 218 PIRSF PIRSF001111 2 217 5.4E-90 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS08425 e518f9ad462483205f5f4b01f34c51c2 218 Gene3D G3DSA:3.40.50.850 4 210 1.2E-57 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS08425 e518f9ad462483205f5f4b01f34c51c2 218 PRINTS PR01398 Isochorismatase signature 111 133 5.6E-48 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS08425 e518f9ad462483205f5f4b01f34c51c2 218 PRINTS PR01398 Isochorismatase signature 167 185 5.6E-48 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS08425 e518f9ad462483205f5f4b01f34c51c2 218 PRINTS PR01398 Isochorismatase signature 79 98 5.6E-48 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS08425 e518f9ad462483205f5f4b01f34c51c2 218 PRINTS PR01398 Isochorismatase signature 3 15 5.6E-48 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS08425 e518f9ad462483205f5f4b01f34c51c2 218 PRINTS PR01398 Isochorismatase signature 185 202 5.6E-48 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS08425 e518f9ad462483205f5f4b01f34c51c2 218 PRINTS PR01398 Isochorismatase signature 62 79 5.6E-48 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS08425 e518f9ad462483205f5f4b01f34c51c2 218 SUPERFAMILY SSF52499 3 211 3.92E-59 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS08425 e518f9ad462483205f5f4b01f34c51c2 218 Pfam PF00857 Isochorismatase family 33 204 8.2E-36 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS08845 500cb3f352f0cd9bb96638df5339fe3b 492 Pfam PF01926 50S ribosome-binding GTPase 273 391 6.6E-20 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS08845 500cb3f352f0cd9bb96638df5339fe3b 492 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 76 431 7.8E-131 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 SMD11_RS08845 500cb3f352f0cd9bb96638df5339fe3b 492 Pfam PF13167 GTP-binding GTPase N-terminal 92 180 6.3E-32 T 06-07-2017 IPR025121 GTPase HflX, N-terminal SMD11_RS08845 500cb3f352f0cd9bb96638df5339fe3b 492 Gene3D G3DSA:3.40.50.300 270 433 1.7E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08845 500cb3f352f0cd9bb96638df5339fe3b 492 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 273 293 4.9E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS08845 500cb3f352f0cd9bb96638df5339fe3b 492 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 340 358 4.9E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS08845 500cb3f352f0cd9bb96638df5339fe3b 492 Pfam PF16360 GTP-binding GTPase Middle Region 182 265 7.4E-29 T 06-07-2017 IPR032305 GTP-binding protein, middle domain SMD11_RS08845 500cb3f352f0cd9bb96638df5339fe3b 492 PIRSF PIRSF006809 67 490 7.4E-158 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 SMD11_RS08845 500cb3f352f0cd9bb96638df5339fe3b 492 Hamap MF_00900 GTPase HflX [hflX]. 95 461 47.557 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 SMD11_RS08845 500cb3f352f0cd9bb96638df5339fe3b 492 SUPERFAMILY SSF52540 272 457 1.14E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11175 5251f71a13d955f40bdae998ac0e7377 484 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 358 440 4.5E-16 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain SMD11_RS11175 5251f71a13d955f40bdae998ac0e7377 484 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 71 240 3.3E-39 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS11175 5251f71a13d955f40bdae998ac0e7377 484 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 70 240 1.4E-38 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS24295 ab7e81a7c447a0b36e404aa71cd92c44 257 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 6 246 3.2E-7 T 06-07-2017 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 SMD11_RS24295 ab7e81a7c447a0b36e404aa71cd92c44 257 Gene3D G3DSA:3.60.21.10 88 248 2.2E-18 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS24295 ab7e81a7c447a0b36e404aa71cd92c44 257 Gene3D G3DSA:3.60.21.10 5 38 2.2E-18 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS24295 ab7e81a7c447a0b36e404aa71cd92c44 257 SUPERFAMILY SSF56300 87 253 6.14E-33 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS24295 ab7e81a7c447a0b36e404aa71cd92c44 257 SUPERFAMILY SSF56300 5 50 6.14E-33 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS08065 28b6a5c9c51194484c7f6c5498b158e5 353 SUPERFAMILY SSF51735 2 304 2.8E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08065 28b6a5c9c51194484c7f6c5498b158e5 353 Gene3D G3DSA:3.40.50.720 2 229 8.2E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS11275 d0fa28c04508b3239c04b420c21559e3 276 Gene3D G3DSA:1.10.3720.10 4 263 4.2E-67 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11275 d0fa28c04508b3239c04b420c21559e3 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 262 1.3E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11275 d0fa28c04508b3239c04b420c21559e3 276 SUPERFAMILY SSF161098 2 276 3.14E-71 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS12360 cfd6c581f90d2a220a5654c654a2b26b 285 Pfam PF13365 Trypsin-like peptidase domain 64 223 4.6E-12 T 06-07-2017 SMD11_RS12360 cfd6c581f90d2a220a5654c654a2b26b 285 SUPERFAMILY SSF50494 42 239 2.9E-15 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS12360 cfd6c581f90d2a220a5654c654a2b26b 285 Gene3D G3DSA:2.40.10.10 185 231 1.2E-5 T 06-07-2017 SMD11_RS20160 b8136af14aa10ca1699d47b1a67a16d4 196 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 118 128 - T 06-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 SMD11_RS20160 b8136af14aa10ca1699d47b1a67a16d4 196 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 20 33 - T 06-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 SMD11_RS20160 b8136af14aa10ca1699d47b1a67a16d4 196 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 9 195 1.5E-51 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SMD11_RS20160 b8136af14aa10ca1699d47b1a67a16d4 196 SUPERFAMILY SSF53178 7 195 1.19E-62 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SMD11_RS20160 b8136af14aa10ca1699d47b1a67a16d4 196 Gene3D G3DSA:3.40.50.1470 4 195 1.3E-69 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SMD11_RS20160 b8136af14aa10ca1699d47b1a67a16d4 196 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 7 188 32.434 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SMD11_RS20160 b8136af14aa10ca1699d47b1a67a16d4 196 Pfam PF01195 Peptidyl-tRNA hydrolase 9 191 8.8E-52 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SMD11_RS25740 2b6eaf5d6c1c0b68a5e858cbcb11dc98 358 Gene3D G3DSA:1.10.3470.10 33 354 2.1E-89 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS25740 2b6eaf5d6c1c0b68a5e858cbcb11dc98 358 SUPERFAMILY SSF81345 29 350 1.83E-67 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS25740 2b6eaf5d6c1c0b68a5e858cbcb11dc98 358 Pfam PF01032 FecCD transport family 47 350 4.2E-80 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD11_RS18785 57a98c4cc92b3f42da047cbd6ffe46b2 143 Gene3D G3DSA:3.10.129.10 3 139 8.2E-40 T 06-07-2017 IPR029069 HotDog domain SMD11_RS18785 57a98c4cc92b3f42da047cbd6ffe46b2 143 SUPERFAMILY SSF54637 5 139 6.31E-32 T 06-07-2017 IPR029069 HotDog domain SMD11_RS18785 57a98c4cc92b3f42da047cbd6ffe46b2 143 Pfam PF01575 MaoC like domain 16 121 1.3E-26 T 06-07-2017 IPR002539 MaoC-like domain SMD11_RS18785 57a98c4cc92b3f42da047cbd6ffe46b2 143 PRINTS PR01483 Fatty acid synthase signature 47 68 1.4E-7 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 SMD11_RS18785 57a98c4cc92b3f42da047cbd6ffe46b2 143 PRINTS PR01483 Fatty acid synthase signature 25 47 1.4E-7 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 SMD11_RS27740 df3b00847ebda6e781c11e10f2b37f98 132 Pfam PF16945 Putative lactococcus lactis phage r1t holin 5 70 2.2E-15 T 06-07-2017 IPR020109 Holin, r1t-type SMD11_RS26975 1abe829392a798ffacef5b785180d4ad 294 Pfam PF03180 NLPA lipoprotein 52 289 1.1E-83 T 06-07-2017 IPR004872 Lipoprotein NlpA family SMD11_RS26975 1abe829392a798ffacef5b785180d4ad 294 SUPERFAMILY SSF53850 52 289 5.54E-73 T 06-07-2017 SMD11_RS26975 1abe829392a798ffacef5b785180d4ad 294 Gene3D G3DSA:3.40.190.10 50 180 1.8E-50 T 06-07-2017 SMD11_RS26975 1abe829392a798ffacef5b785180d4ad 294 PIRSF PIRSF002854 9 289 2.3E-96 T 06-07-2017 IPR004872 Lipoprotein NlpA family SMD11_RS30310 51331eec3f48a4beb135d774c20a33a8 451 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 390 399 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS30310 51331eec3f48a4beb135d774c20a33a8 451 SUPERFAMILY SSF48264 16 448 4.58E-103 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30310 51331eec3f48a4beb135d774c20a33a8 451 PRINTS PR00385 P450 superfamily signature 261 278 9.9E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30310 51331eec3f48a4beb135d774c20a33a8 451 PRINTS PR00385 P450 superfamily signature 397 408 9.9E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30310 51331eec3f48a4beb135d774c20a33a8 451 PRINTS PR00385 P450 superfamily signature 313 324 9.9E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30310 51331eec3f48a4beb135d774c20a33a8 451 PRINTS PR00385 P450 superfamily signature 388 397 9.9E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30310 51331eec3f48a4beb135d774c20a33a8 451 Gene3D G3DSA:1.10.630.10 16 449 3.2E-112 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30310 51331eec3f48a4beb135d774c20a33a8 451 PRINTS PR00465 E-class P450 group IV signature 252 278 2.5E-18 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30310 51331eec3f48a4beb135d774c20a33a8 451 PRINTS PR00465 E-class P450 group IV signature 341 355 2.5E-18 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30310 51331eec3f48a4beb135d774c20a33a8 451 PRINTS PR00465 E-class P450 group IV signature 357 375 2.5E-18 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30310 51331eec3f48a4beb135d774c20a33a8 451 PRINTS PR00465 E-class P450 group IV signature 381 397 2.5E-18 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30310 51331eec3f48a4beb135d774c20a33a8 451 PRINTS PR00465 E-class P450 group IV signature 12 29 2.5E-18 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30310 51331eec3f48a4beb135d774c20a33a8 451 PRINTS PR00465 E-class P450 group IV signature 308 324 2.5E-18 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30310 51331eec3f48a4beb135d774c20a33a8 451 PRINTS PR00465 E-class P450 group IV signature 397 415 2.5E-18 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS30310 51331eec3f48a4beb135d774c20a33a8 451 Pfam PF00067 Cytochrome P450 17 433 4.4E-77 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS21550 b8fefae43034ed9fe12a074f70f5731b 225 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 21 144 1.1E-6 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD11_RS16560 ffb8d43106b394c845c60b7d5151c260 525 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 10 490 3.6E-173 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 SMD11_RS26140 5f95027760731ea3ebb3c66ed586dc97 364 Pfam PF13480 Acetyltransferase (GNAT) domain 160 301 6.3E-39 T 06-07-2017 SMD11_RS26140 5f95027760731ea3ebb3c66ed586dc97 364 SUPERFAMILY SSF55729 156 323 6.68E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS32265 f8830e84c2e491b488fd05116619bf28 232 Pfam PF01965 DJ-1/PfpI family 116 198 4.3E-11 T 06-07-2017 IPR002818 DJ-1/PfpI SMD11_RS32265 f8830e84c2e491b488fd05116619bf28 232 SUPERFAMILY SSF52317 1 77 9.49E-28 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS32265 f8830e84c2e491b488fd05116619bf28 232 SUPERFAMILY SSF52317 105 216 9.49E-28 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS32265 f8830e84c2e491b488fd05116619bf28 232 Gene3D G3DSA:3.40.50.880 1 220 7.1E-55 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS13165 fd12cf18b1d6d502c50fb408480a2951 523 Pfam PF00732 GMC oxidoreductase 14 298 7.1E-55 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS13165 fd12cf18b1d6d502c50fb408480a2951 523 Gene3D G3DSA:3.50.50.60 449 512 9.8E-104 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13165 fd12cf18b1d6d502c50fb408480a2951 523 Gene3D G3DSA:3.50.50.60 10 133 9.8E-104 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13165 fd12cf18b1d6d502c50fb408480a2951 523 Gene3D G3DSA:3.50.50.60 185 315 9.8E-104 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13165 fd12cf18b1d6d502c50fb408480a2951 523 Pfam PF05199 GMC oxidoreductase 368 508 3.6E-39 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS13165 fd12cf18b1d6d502c50fb408480a2951 523 SUPERFAMILY SSF54373 292 456 5.69E-41 T 06-07-2017 SMD11_RS13165 fd12cf18b1d6d502c50fb408480a2951 523 SUPERFAMILY SSF51905 455 513 2.24E-71 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13165 fd12cf18b1d6d502c50fb408480a2951 523 SUPERFAMILY SSF51905 10 290 2.24E-71 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13165 fd12cf18b1d6d502c50fb408480a2951 523 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 256 270 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS04435 ddc8a0f76f965dd6755fedcb2e32045d 191 Pfam PF13581 Histidine kinase-like ATPase domain 75 187 4.3E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS04435 ddc8a0f76f965dd6755fedcb2e32045d 191 SUPERFAMILY SSF55874 102 190 4.7E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS04435 ddc8a0f76f965dd6755fedcb2e32045d 191 Gene3D G3DSA:3.30.565.10 101 190 2.9E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS04000 f31bcb94482d95fa9f8526d9b4c8b523 235 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 208 228 3.7E-9 T 06-07-2017 IPR024726 Ferric iron reductase, C-terminal GO:0051537 SMD11_RS09435 63f2a4be899933543c94d91409cf1854 504 Pfam PF07690 Major Facilitator Superfamily 20 410 8.9E-53 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS09435 63f2a4be899933543c94d91409cf1854 504 Gene3D G3DSA:1.20.1250.20 456 480 4.9E-14 T 06-07-2017 SMD11_RS09435 63f2a4be899933543c94d91409cf1854 504 Gene3D G3DSA:1.20.1250.20 16 195 1.5E-27 T 06-07-2017 SMD11_RS09435 63f2a4be899933543c94d91409cf1854 504 Gene3D G3DSA:1.20.1250.20 264 422 4.9E-14 T 06-07-2017 SMD11_RS09435 63f2a4be899933543c94d91409cf1854 504 SUPERFAMILY SSF103473 6 201 4.84E-54 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS09435 63f2a4be899933543c94d91409cf1854 504 SUPERFAMILY SSF103473 249 421 4.84E-54 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS09435 63f2a4be899933543c94d91409cf1854 504 SUPERFAMILY SSF103473 454 478 4.84E-54 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS31120 a8703dc56d89944d723576d1340e4571 176 Gene3D G3DSA:1.10.10.60 1 48 2.8E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS31120 a8703dc56d89944d723576d1340e4571 176 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 41 4.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS31120 a8703dc56d89944d723576d1340e4571 176 SUPERFAMILY SSF46689 2 68 2.29E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS31120 a8703dc56d89944d723576d1340e4571 176 SUPERFAMILY SSF48498 62 174 1.36E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS31120 a8703dc56d89944d723576d1340e4571 176 Gene3D G3DSA:1.10.357.10 56 175 3.1E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS15925 9613aefff313980dd84b0c9045cf498b 662 SUPERFAMILY SSF51905 126 202 1.57E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15925 9613aefff313980dd84b0c9045cf498b 662 SUPERFAMILY SSF51905 5 53 1.57E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15925 9613aefff313980dd84b0c9045cf498b 662 Gene3D G3DSA:3.50.50.60 5 202 8.4E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15925 9613aefff313980dd84b0c9045cf498b 662 Gene3D G3DSA:3.50.50.60 575 613 8.4E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS15925 9613aefff313980dd84b0c9045cf498b 662 Pfam PF13454 FAD-NAD(P)-binding 10 195 3.0E-44 T 06-07-2017 SMD11_RS02215 80ee9d8b22ddcae504f36f6260ad6842 652 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 442 565 9.8E-24 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 SMD11_RS02215 80ee9d8b22ddcae504f36f6260ad6842 652 SMART SM00382 437 569 4.0E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS02215 80ee9d8b22ddcae504f36f6260ad6842 652 SUPERFAMILY SSF52540 394 618 4.86E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS02215 80ee9d8b22ddcae504f36f6260ad6842 652 Gene3D G3DSA:3.40.50.300 394 599 5.3E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19415 dfeb941971aa683ccd9d9795567a0718 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 229 1.2E-31 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS19415 dfeb941971aa683ccd9d9795567a0718 260 SUPERFAMILY SSF52096 6 235 5.76E-50 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS19415 dfeb941971aa683ccd9d9795567a0718 260 Gene3D G3DSA:3.90.226.10 6 236 9.4E-49 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS22010 0674cd77e490c0f396154e1232f5268d 742 Gene3D G3DSA:3.40.50.300 161 375 9.5E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22010 0674cd77e490c0f396154e1232f5268d 742 Pfam PF01926 50S ribosome-binding GTPase 178 294 2.3E-7 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 SMD11_RS22010 0674cd77e490c0f396154e1232f5268d 742 SUPERFAMILY SSF52540 167 376 2.03E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03265 f4de344955b0d6a720d9f0f5c1c86cf3 296 ProSitePatterns PS00211 ABC transporters family signature. 188 202 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS03265 f4de344955b0d6a720d9f0f5c1c86cf3 296 Gene3D G3DSA:3.40.50.300 51 287 3.7E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03265 f4de344955b0d6a720d9f0f5c1c86cf3 296 SMART SM00382 77 264 1.5E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS03265 f4de344955b0d6a720d9f0f5c1c86cf3 296 SUPERFAMILY SSF52540 52 286 1.39E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS03265 f4de344955b0d6a720d9f0f5c1c86cf3 296 Pfam PF00005 ABC transporter 68 216 1.7E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS03265 f4de344955b0d6a720d9f0f5c1c86cf3 296 PIRSF PIRSF039085 49 292 4.4E-99 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SMD11_RS25420 d1afb91c3b3617702ba5ef2ccde7617d 135 SUPERFAMILY SSF54593 13 133 6.44E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS25420 d1afb91c3b3617702ba5ef2ccde7617d 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 128 1.8E-5 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS25420 d1afb91c3b3617702ba5ef2ccde7617d 135 Gene3D G3DSA:3.10.180.10 10 131 2.8E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS21570 cb2750b772b01d7f630cba8a67545ccc 365 Pfam PF00296 Luciferase-like monooxygenase 23 335 1.3E-38 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS21570 cb2750b772b01d7f630cba8a67545ccc 365 SUPERFAMILY SSF51679 20 358 5.06E-78 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS21570 cb2750b772b01d7f630cba8a67545ccc 365 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 21 358 7.6E-131 T 06-07-2017 IPR019949 Luciferase family oxidoreductase, group 1 SMD11_RS21570 cb2750b772b01d7f630cba8a67545ccc 365 Gene3D G3DSA:3.20.20.30 17 358 3.3E-91 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS01580 cc4bbe731961354dd6cef13ad5ebdaff 256 SUPERFAMILY SSF53474 9 254 8.04E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01580 cc4bbe731961354dd6cef13ad5ebdaff 256 Pfam PF00561 alpha/beta hydrolase fold 22 242 7.2E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS01580 cc4bbe731961354dd6cef13ad5ebdaff 256 Gene3D G3DSA:3.40.50.1820 8 255 8.1E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS26865 cb099817683d2790e39f84855e63ff98 451 Gene3D G3DSA:3.90.1150.10 327 444 1.1E-24 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS26865 cb099817683d2790e39f84855e63ff98 451 Gene3D G3DSA:3.40.640.10 71 326 1.6E-86 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS26865 cb099817683d2790e39f84855e63ff98 451 Pfam PF00266 Aminotransferase class-V 59 439 9.1E-143 T 06-07-2017 IPR000192 Aminotransferase class V domain SMD11_RS26865 cb099817683d2790e39f84855e63ff98 451 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 41 450 8.8E-173 T 06-07-2017 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SMD11_RS26865 cb099817683d2790e39f84855e63ff98 451 SUPERFAMILY SSF53383 36 446 2.04E-120 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS18365 4f6ac7d5b357573ed932b8d53e2dc3de 438 SUPERFAMILY SSF53383 9 429 1.73E-115 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS18365 4f6ac7d5b357573ed932b8d53e2dc3de 438 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 13 426 1.7E-179 T 06-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 SMD11_RS18365 4f6ac7d5b357573ed932b8d53e2dc3de 438 Pfam PF00202 Aminotransferase class-III 42 425 6.2E-79 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS18365 4f6ac7d5b357573ed932b8d53e2dc3de 438 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 12 433 96.145 T 06-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 SMD11_RS18365 4f6ac7d5b357573ed932b8d53e2dc3de 438 Gene3D G3DSA:3.90.1150.10 10 78 7.2E-36 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS18365 4f6ac7d5b357573ed932b8d53e2dc3de 438 Gene3D G3DSA:3.90.1150.10 327 429 7.2E-36 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS18365 4f6ac7d5b357573ed932b8d53e2dc3de 438 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 243 279 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS18365 4f6ac7d5b357573ed932b8d53e2dc3de 438 Gene3D G3DSA:3.40.640.10 79 325 9.3E-77 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS33010 1be80ec81302d4b2bf0a514b82252106 264 Gene3D G3DSA:3.40.50.1820 177 234 5.4E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS33010 1be80ec81302d4b2bf0a514b82252106 264 Gene3D G3DSA:3.40.50.1820 8 126 5.4E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS33010 1be80ec81302d4b2bf0a514b82252106 264 Pfam PF00975 Thioesterase domain 22 231 2.1E-20 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS33010 1be80ec81302d4b2bf0a514b82252106 264 SUPERFAMILY SSF53474 6 242 2.63E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS00815 bb9c8802ee75ca6da2e386be9f294be5 462 SUPERFAMILY SSF52777 13 194 8.15E-39 T 06-07-2017 SMD11_RS00815 bb9c8802ee75ca6da2e386be9f294be5 462 Pfam PF13745 HxxPF-repeated domain 338 425 6.5E-11 T 06-07-2017 SMD11_RS00815 bb9c8802ee75ca6da2e386be9f294be5 462 Pfam PF00668 Condensation domain 8 314 1.1E-52 T 06-07-2017 IPR001242 Condensation domain SMD11_RS00815 bb9c8802ee75ca6da2e386be9f294be5 462 SUPERFAMILY SSF52777 210 448 1.11E-39 T 06-07-2017 SMD11_RS30820 3a92f42adac1f3bad4fa28b4fa65bfa2 312 Pfam PF00106 short chain dehydrogenase 19 221 8.8E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30820 3a92f42adac1f3bad4fa28b4fa65bfa2 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 3.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30820 3a92f42adac1f3bad4fa28b4fa65bfa2 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 3.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30820 3a92f42adac1f3bad4fa28b4fa65bfa2 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 218 3.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS30820 3a92f42adac1f3bad4fa28b4fa65bfa2 312 Gene3D G3DSA:3.40.50.720 16 268 1.1E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS30820 3a92f42adac1f3bad4fa28b4fa65bfa2 312 SUPERFAMILY SSF51735 16 268 1.52E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS21595 6b5009682e0d3ce6318d71e0f4ff34dc 267 SUPERFAMILY SSF52833 86 256 3.03E-41 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS21595 6b5009682e0d3ce6318d71e0f4ff34dc 267 Gene3D G3DSA:3.40.30.10 90 260 8.5E-44 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS21595 6b5009682e0d3ce6318d71e0f4ff34dc 267 Pfam PF13462 Thioredoxin 95 256 8.4E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS31860 ef144112416538ca1995bb6fff55ad60 238 Pfam PF06197 Protein of unknown function (DUF998) 34 223 1.9E-21 T 06-07-2017 IPR009339 Protein of unknown function DUF998 SMD11_RS33235 9c07740703b5353f5162529f5fe1ffee 355 Pfam PF01658 Myo-inositol-1-phosphate synthase 195 300 8.9E-21 T 06-07-2017 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 SMD11_RS33235 9c07740703b5353f5162529f5fe1ffee 355 SUPERFAMILY SSF55347 194 300 1.05E-21 T 06-07-2017 SMD11_RS33235 9c07740703b5353f5162529f5fe1ffee 355 Gene3D G3DSA:3.40.50.720 1 193 2.4E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33235 9c07740703b5353f5162529f5fe1ffee 355 Gene3D G3DSA:3.40.50.720 301 351 2.4E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33235 9c07740703b5353f5162529f5fe1ffee 355 Gene3D G3DSA:3.30.360.10 194 300 1.2E-28 T 06-07-2017 SMD11_RS33235 9c07740703b5353f5162529f5fe1ffee 355 SUPERFAMILY SSF51735 297 350 6.4E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33235 9c07740703b5353f5162529f5fe1ffee 355 SUPERFAMILY SSF51735 3 189 6.4E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS18780 4254db0f1bdf21078a681ec76cc89045 150 Pfam PF13452 N-terminal half of MaoC dehydratase 7 137 1.8E-37 T 06-07-2017 SMD11_RS18780 4254db0f1bdf21078a681ec76cc89045 150 Hamap MF_00799 UPF0336 protein . 1 148 37.437 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 SMD11_RS18780 4254db0f1bdf21078a681ec76cc89045 150 Gene3D G3DSA:3.10.129.10 1 148 2.6E-39 T 06-07-2017 IPR029069 HotDog domain SMD11_RS18780 4254db0f1bdf21078a681ec76cc89045 150 SUPERFAMILY SSF54637 7 147 6.45E-39 T 06-07-2017 IPR029069 HotDog domain SMD11_RS18780 4254db0f1bdf21078a681ec76cc89045 150 PIRSF PIRSF018072 1 150 8.8E-62 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 SMD11_RS08730 810e775202b091571d1ca80b7f596329 685 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 44 216 2.6E-13 T 06-07-2017 IPR032856 Putative glycogen debranching enzyme, N-terminal SMD11_RS08730 810e775202b091571d1ca80b7f596329 685 SUPERFAMILY SSF48208 242 670 2.21E-26 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 SMD11_RS30530 f76973f49516c68e85d0a03f58429814 222 Pfam PF13349 Putative adhesin 73 219 1.5E-8 T 06-07-2017 IPR025164 Putative adhesin SMD11_RS32795 0789e7d1405ad65480ef22e3d8f5eaaa 233 Gene3D G3DSA:3.40.50.720 1 233 3.3E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32795 0789e7d1405ad65480ef22e3d8f5eaaa 233 SUPERFAMILY SSF51735 1 232 1.14E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32795 0789e7d1405ad65480ef22e3d8f5eaaa 233 Pfam PF13460 NAD(P)H-binding 7 219 2.5E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS06560 19ee723ed6f171b16ca0cec49c7c8e60 172 SUPERFAMILY SSF46767 80 160 1.01E-31 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS06560 19ee723ed6f171b16ca0cec49c7c8e60 172 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 81 160 7.7E-34 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS06560 19ee723ed6f171b16ca0cec49c7c8e60 172 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 8 163 38.107 T 06-07-2017 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 SMD11_RS06560 19ee723ed6f171b16ca0cec49c7c8e60 172 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 131 137 - T 06-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS06560 19ee723ed6f171b16ca0cec49c7c8e60 172 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 11 77 2.2E-5 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS06560 19ee723ed6f171b16ca0cec49c7c8e60 172 SUPERFAMILY SSF53155 9 86 6.47E-18 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS06560 19ee723ed6f171b16ca0cec49c7c8e60 172 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 82 160 2.6E-32 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SMD11_RS06560 19ee723ed6f171b16ca0cec49c7c8e60 172 Gene3D G3DSA:1.10.10.10 80 161 2.7E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23785 dd5c38ff9d31a770fea534d992d3d1b6 274 Pfam PF01061 ABC-2 type transporter 27 238 4.7E-33 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD11_RS23785 dd5c38ff9d31a770fea534d992d3d1b6 274 PIRSF PIRSF006648 2 274 4.2E-80 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS11115 22f8de3482a17e4083c5c8e020784061 124 Pfam PF00717 Peptidase S24-like 1 55 2.5E-8 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B SMD11_RS11115 22f8de3482a17e4083c5c8e020784061 124 SUPERFAMILY SSF51306 1 85 1.18E-19 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C SMD11_RS11115 22f8de3482a17e4083c5c8e020784061 124 Gene3D G3DSA:2.10.109.10 1 83 6.2E-17 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain SMD11_RS11115 22f8de3482a17e4083c5c8e020784061 124 TIGRFAM TIGR02754 sod_Ni_protease: nickel-type superoxide dismutase maturation protease 1 76 1.6E-20 T 06-07-2017 IPR014124 Peptidase S26A, superoxide dismutase maturation protease, nickel-type SMD11_RS09885 b675afb9d991d4e83ffecfda866ad339 135 Pfam PF05331 Protein of unknown function (DUF742) 23 135 1.4E-38 T 06-07-2017 IPR007995 Protein of unknown function DUF742 SMD11_RS13785 2f8654523c3c4709e83cf984edf41b6e 1144 Gene3D G3DSA:3.30.565.10 23 233 1.9E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS13785 2f8654523c3c4709e83cf984edf41b6e 1144 SUPERFAMILY SSF55874 43 148 2.51E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS00700 0aa8c9b4d7dc2d5e6d0ab5dbebaf8cb2 137 Pfam PF01610 Transposase 12 128 8.6E-15 T 06-07-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain SMD11_RS29115 a80fe04d85f227bc01332e6ca7f48c20 389 Gene3D G3DSA:3.40.47.10 11 119 2.0E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29115 a80fe04d85f227bc01332e6ca7f48c20 389 Gene3D G3DSA:3.40.47.10 197 221 2.0E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29115 a80fe04d85f227bc01332e6ca7f48c20 389 Gene3D G3DSA:3.40.47.10 264 368 4.1E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29115 a80fe04d85f227bc01332e6ca7f48c20 389 SUPERFAMILY SSF53901 5 123 4.02E-23 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS29115 a80fe04d85f227bc01332e6ca7f48c20 389 SUPERFAMILY SSF53901 190 376 4.02E-23 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS03800 44fdd9aef2a1b8542d7c2820e693bb30 257 Gene3D G3DSA:3.90.226.10 9 223 1.6E-55 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS03800 44fdd9aef2a1b8542d7c2820e693bb30 257 SUPERFAMILY SSF52096 7 237 1.85E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS03800 44fdd9aef2a1b8542d7c2820e693bb30 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 209 1.7E-36 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS09990 06ebf2a58aaf136fb92b829d81a6e25a 135 Pfam PF08239 Bacterial SH3 domain 69 126 2.1E-8 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type SMD11_RS26085 20d8d73d6e143da30fc9728ef1200286 582 Pfam PF06276 Ferric iron reductase FhuF-like transporter 392 547 2.4E-8 T 06-07-2017 IPR022770 Ferric iron reductase FhuF domain SMD11_RS26085 20d8d73d6e143da30fc9728ef1200286 582 Pfam PF04183 IucA / IucC family 150 367 5.5E-29 T 06-07-2017 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 SMD11_RS25730 e66eb19f65827284a03e7540b3b14b3e 353 Gene3D G3DSA:3.40.50.1980 61 187 4.7E-8 T 06-07-2017 SMD11_RS25730 e66eb19f65827284a03e7540b3b14b3e 353 SUPERFAMILY SSF53807 61 346 4.71E-27 T 06-07-2017 SMD11_RS25730 e66eb19f65827284a03e7540b3b14b3e 353 Gene3D G3DSA:3.40.50.1980 204 334 1.2E-13 T 06-07-2017 SMD11_RS25730 e66eb19f65827284a03e7540b3b14b3e 353 Pfam PF01497 Periplasmic binding protein 125 321 9.5E-13 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD11_RS09215 9e477b6a4328b90971eb37399c203fd5 321 Pfam PF01687 Riboflavin kinase 188 309 1.1E-29 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 SMD11_RS09215 9e477b6a4328b90971eb37399c203fd5 321 Gene3D G3DSA:2.40.30.30 184 317 2.1E-41 T 06-07-2017 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 SMD11_RS09215 9e477b6a4328b90971eb37399c203fd5 321 SMART SM00904 187 312 1.5E-42 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 SMD11_RS09215 9e477b6a4328b90971eb37399c203fd5 321 Pfam PF06574 FAD synthetase 12 158 3.6E-50 T 06-07-2017 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD11_RS09215 9e477b6a4328b90971eb37399c203fd5 321 SUPERFAMILY SSF82114 178 313 8.72E-39 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 SMD11_RS09215 9e477b6a4328b90971eb37399c203fd5 321 SUPERFAMILY SSF52374 16 179 5.33E-33 T 06-07-2017 SMD11_RS09215 9e477b6a4328b90971eb37399c203fd5 321 Gene3D G3DSA:3.40.50.620 3 183 4.8E-61 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS09215 9e477b6a4328b90971eb37399c203fd5 321 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 310 6.8E-62 T 06-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD11_RS09215 9e477b6a4328b90971eb37399c203fd5 321 PIRSF PIRSF004491 1 318 1.4E-91 T 06-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 SMD11_RS31695 f03629b8a9e3417c28cde36797dbefb5 298 Gene3D G3DSA:2.40.10.10 100 178 1.3E-6 T 06-07-2017 SMD11_RS31695 f03629b8a9e3417c28cde36797dbefb5 298 SUPERFAMILY SSF50494 83 276 1.03E-15 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS28545 db30e1a638df35cfdb6a63cd6c575210 195 SUPERFAMILY SSF55729 1 149 2.19E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS28545 db30e1a638df35cfdb6a63cd6c575210 195 Gene3D G3DSA:3.40.630.30 1 141 5.1E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS28545 db30e1a638df35cfdb6a63cd6c575210 195 Pfam PF00583 Acetyltransferase (GNAT) family 62 145 5.1E-11 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS02910 33f1e18357a67322c32364769b572319 389 TIGRFAM TIGR03469 HpnB: hopene-associated glycosyltransferase HpnB 5 383 2.9E-145 T 06-07-2017 IPR017832 Glycosyl transferase, family 2, hopene-associated, HpnB SMD11_RS02910 33f1e18357a67322c32364769b572319 389 Pfam PF13641 Glycosyltransferase like family 2 42 252 4.1E-22 T 06-07-2017 SMD11_RS02910 33f1e18357a67322c32364769b572319 389 SUPERFAMILY SSF53448 33 288 3.38E-37 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS02910 33f1e18357a67322c32364769b572319 389 Gene3D G3DSA:3.90.550.10 43 252 7.2E-21 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS16455 fe4de74a6cb3a753843f84efa86b75a7 264 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 259 1.6E-44 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS16455 fe4de74a6cb3a753843f84efa86b75a7 264 Gene3D G3DSA:3.40.50.1000 2 73 3.4E-50 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS16455 fe4de74a6cb3a753843f84efa86b75a7 264 Gene3D G3DSA:3.40.50.1000 168 263 3.4E-50 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS16455 fe4de74a6cb3a753843f84efa86b75a7 264 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 232 2.6E-23 T 06-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SMD11_RS16455 fe4de74a6cb3a753843f84efa86b75a7 264 SUPERFAMILY SSF56784 2 263 2.5E-57 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS10875 c52211653bb0961fea0d410e36165982 363 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 64 77 - T 06-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 SMD11_RS10875 c52211653bb0961fea0d410e36165982 363 Gene3D G3DSA:3.40.50.1100 72 156 1.8E-42 T 06-07-2017 SMD11_RS10875 c52211653bb0961fea0d410e36165982 363 SUPERFAMILY SSF53686 14 344 6.29E-101 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS10875 c52211653bb0961fea0d410e36165982 363 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 37 330 8.1E-73 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS10875 c52211653bb0961fea0d410e36165982 363 TIGRFAM TIGR00260 thrC: threonine synthase 20 337 9.1E-96 T 06-07-2017 IPR004450 Threonine synthase-like SMD11_RS10875 c52211653bb0961fea0d410e36165982 363 PIRSF PIRSF038945 5 362 2.3E-165 T 06-07-2017 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 SMD11_RS10875 c52211653bb0961fea0d410e36165982 363 Gene3D G3DSA:3.40.50.1100 157 338 7.2E-47 T 06-07-2017 SMD11_RS11805 837285fa392239864d2cd3a525e144e5 63 Pfam PF07411 Domain of unknown function (DUF1508) 10 57 3.0E-24 T 06-07-2017 IPR010879 Domain of unknown function DUF1508 SMD11_RS11805 837285fa392239864d2cd3a525e144e5 63 SUPERFAMILY SSF160113 1 57 3.92E-21 T 06-07-2017 IPR010879 Domain of unknown function DUF1508 SMD11_RS11805 837285fa392239864d2cd3a525e144e5 63 Gene3D G3DSA:3.30.160.160 3 48 7.6E-24 T 06-07-2017 IPR010879 Domain of unknown function DUF1508 SMD11_RS20280 e1223587ba5fec725554597ab679fa19 420 Gene3D G3DSA:1.10.630.10 14 417 2.7E-137 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20280 e1223587ba5fec725554597ab679fa19 420 PRINTS PR00359 B-class P450 signature 147 163 4.1E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20280 e1223587ba5fec725554597ab679fa19 420 PRINTS PR00359 B-class P450 signature 101 112 4.1E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20280 e1223587ba5fec725554597ab679fa19 420 PRINTS PR00359 B-class P450 signature 334 349 4.1E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20280 e1223587ba5fec725554597ab679fa19 420 PRINTS PR00359 B-class P450 signature 355 364 4.1E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20280 e1223587ba5fec725554597ab679fa19 420 PRINTS PR00359 B-class P450 signature 306 333 4.1E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20280 e1223587ba5fec725554597ab679fa19 420 PRINTS PR00359 B-class P450 signature 288 299 4.1E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20280 e1223587ba5fec725554597ab679fa19 420 PRINTS PR00359 B-class P450 signature 164 179 4.1E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20280 e1223587ba5fec725554597ab679fa19 420 PRINTS PR00359 B-class P450 signature 364 375 4.1E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20280 e1223587ba5fec725554597ab679fa19 420 PRINTS PR00359 B-class P450 signature 202 224 4.1E-60 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS20280 e1223587ba5fec725554597ab679fa19 420 Pfam PF00067 Cytochrome P450 194 384 5.7E-23 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20280 e1223587ba5fec725554597ab679fa19 420 SUPERFAMILY SSF48264 16 416 1.17E-104 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS16045 38571742b1f491f592102e065847b37a 381 Pfam PF13546 DDE superfamily endonuclease 8 258 3.3E-41 T 06-07-2017 SMD11_RS04345 4bebe0182707375aadf6efe9e50e9aba 406 SUPERFAMILY SSF56601 53 367 2.35E-74 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS04345 4bebe0182707375aadf6efe9e50e9aba 406 Pfam PF00144 Beta-lactamase 48 347 9.4E-57 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS04345 4bebe0182707375aadf6efe9e50e9aba 406 Gene3D G3DSA:3.40.710.10 54 367 1.5E-72 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS25320 53d00c8a9c8be8c5d95282700c312874 132 SUPERFAMILY SSF51182 3 127 6.44E-20 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS25320 53d00c8a9c8be8c5d95282700c312874 132 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 119 9.0E-64 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS25320 53d00c8a9c8be8c5d95282700c312874 132 Gene3D G3DSA:2.60.120.10 36 112 8.3E-12 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS25320 53d00c8a9c8be8c5d95282700c312874 132 Hamap MF_01255 L-ectoine synthase [ectC]. 1 129 39.232 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS25320 53d00c8a9c8be8c5d95282700c312874 132 Pfam PF06339 Ectoine synthase 2 127 1.7E-56 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SMD11_RS04060 4c23961cca9701bcc7f088d7e1db5cd8 414 Pfam PF13535 ATP-grasp domain 147 296 2.1E-16 T 06-07-2017 SMD11_RS04060 4c23961cca9701bcc7f088d7e1db5cd8 414 Gene3D G3DSA:3.30.470.20 106 402 9.8E-30 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS04060 4c23961cca9701bcc7f088d7e1db5cd8 414 SUPERFAMILY SSF56059 100 327 5.83E-38 T 06-07-2017 SMD11_RS04060 4c23961cca9701bcc7f088d7e1db5cd8 414 SMART SM01209 111 291 3.5E-5 T 06-07-2017 SMD11_RS19145 0c4e5d455d60e4a14cf05ceb56e3a501 319 Gene3D G3DSA:1.10.1660.10 8 125 8.6E-28 T 06-07-2017 SMD11_RS19145 0c4e5d455d60e4a14cf05ceb56e3a501 319 SUPERFAMILY SSF46955 8 109 7.69E-24 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS19145 0c4e5d455d60e4a14cf05ceb56e3a501 319 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 6.4E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS19145 0c4e5d455d60e4a14cf05ceb56e3a501 319 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 6.4E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS19145 0c4e5d455d60e4a14cf05ceb56e3a501 319 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 6.4E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS19145 0c4e5d455d60e4a14cf05ceb56e3a501 319 Pfam PF13411 MerR HTH family regulatory protein 8 75 1.7E-16 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS19145 0c4e5d455d60e4a14cf05ceb56e3a501 319 SMART SM00422 7 76 1.4E-23 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS20050 c9fbdbece3238d0f1cec0d2c26ad042e 283 SUPERFAMILY SSF103481 40 135 1.83E-10 T 06-07-2017 SMD11_RS20050 c9fbdbece3238d0f1cec0d2c26ad042e 283 Pfam PF00892 EamA-like transporter family 146 280 3.7E-8 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS20050 c9fbdbece3238d0f1cec0d2c26ad042e 283 SUPERFAMILY SSF103481 199 281 1.09E-7 T 06-07-2017 SMD11_RS31160 fbf089c0eccab22363a4965b51f1f0c4 215 Pfam PF14273 Domain of unknown function (DUF4360) 35 214 1.5E-67 T 06-07-2017 IPR025649 Protein of unknown function DUF4360 SMD11_RS26155 7e9d840cea827a98001b90012b6ab82e 561 SMART SM00220 21 278 1.0E-62 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS26155 7e9d840cea827a98001b90012b6ab82e 561 Gene3D G3DSA:3.30.200.20 15 90 1.4E-21 T 06-07-2017 SMD11_RS26155 7e9d840cea827a98001b90012b6ab82e 561 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 27 50 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS26155 7e9d840cea827a98001b90012b6ab82e 561 Pfam PF00069 Protein kinase domain 21 271 1.8E-45 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS26155 7e9d840cea827a98001b90012b6ab82e 561 SUPERFAMILY SSF56112 17 278 6.88E-68 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS26155 7e9d840cea827a98001b90012b6ab82e 561 Gene3D G3DSA:1.10.510.10 91 273 5.1E-48 T 06-07-2017 SMD11_RS26155 7e9d840cea827a98001b90012b6ab82e 561 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 144 156 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS16980 74ea576f7dc6fa14471d45c767507a6f 220 Gene3D G3DSA:1.20.120.20 17 102 5.6E-4 T 06-07-2017 SMD11_RS16980 74ea576f7dc6fa14471d45c767507a6f 220 ProDom PD190647 REGULATORY RESISTANCE TRANSCRIPTION TRANSCRIPTIONAL ANTIBIOTIC DNA-BINDING ACTIVATOR REGULATION ORF699 NOSIHEPTIDE 1 207 2.0E-42 T 06-07-2017 SMD11_RS16980 74ea576f7dc6fa14471d45c767507a6f 220 SUPERFAMILY SSF58113 24 101 5.36E-5 T 06-07-2017 SMD11_RS34165 8e2031d451884d88dcc7dd7fed1913da 441 Pfam PF01979 Amidohydrolase family 55 409 1.8E-28 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 SMD11_RS34165 8e2031d451884d88dcc7dd7fed1913da 441 Gene3D G3DSA:3.20.20.140 70 379 4.1E-54 T 06-07-2017 SMD11_RS34165 8e2031d451884d88dcc7dd7fed1913da 441 SUPERFAMILY SSF51338 5 58 2.47E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS34165 8e2031d451884d88dcc7dd7fed1913da 441 SUPERFAMILY SSF51338 361 434 2.47E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS34165 8e2031d451884d88dcc7dd7fed1913da 441 Gene3D G3DSA:2.30.40.10 5 69 7.2E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS34165 8e2031d451884d88dcc7dd7fed1913da 441 SUPERFAMILY SSF51556 58 362 1.2E-52 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS04665 c073228aa586463412cff50a9daa873a 220 Gene3D G3DSA:1.10.3720.10 12 217 8.1E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS04665 c073228aa586463412cff50a9daa873a 220 SUPERFAMILY SSF161098 13 205 1.31E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS04665 c073228aa586463412cff50a9daa873a 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 217 8.0E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS15775 cb248fe6ec8dfbefa306e525c3c83257 308 SUPERFAMILY SSF51735 35 301 3.38E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS15775 cb248fe6ec8dfbefa306e525c3c83257 308 Gene3D G3DSA:3.40.50.720 36 238 6.8E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS15775 cb248fe6ec8dfbefa306e525c3c83257 308 Pfam PF13460 NAD(P)H-binding 42 204 2.2E-13 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS11695 a9ec01a263038f59bbf18fd422d2b4dd 328 Gene3D G3DSA:3.40.50.1820 27 315 2.0E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS11695 a9ec01a263038f59bbf18fd422d2b4dd 328 Pfam PF12697 Alpha/beta hydrolase family 55 308 2.3E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS11695 a9ec01a263038f59bbf18fd422d2b4dd 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 3.4E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS11695 a9ec01a263038f59bbf18fd422d2b4dd 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 77 92 3.4E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS11695 a9ec01a263038f59bbf18fd422d2b4dd 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 136 149 3.4E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS11695 a9ec01a263038f59bbf18fd422d2b4dd 328 SUPERFAMILY SSF53474 26 315 1.49E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS08655 19cd0b51767140e818b3a7e16d71e583 384 PRINTS PR00143 Citrate synthase signature 182 197 1.1E-32 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS08655 19cd0b51767140e818b3a7e16d71e583 384 PRINTS PR00143 Citrate synthase signature 204 232 1.1E-32 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS08655 19cd0b51767140e818b3a7e16d71e583 384 PRINTS PR00143 Citrate synthase signature 316 332 1.1E-32 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS08655 19cd0b51767140e818b3a7e16d71e583 384 PRINTS PR00143 Citrate synthase signature 257 277 1.1E-32 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS08655 19cd0b51767140e818b3a7e16d71e583 384 PRINTS PR00143 Citrate synthase signature 133 146 1.1E-32 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS08655 19cd0b51767140e818b3a7e16d71e583 384 PRINTS PR00143 Citrate synthase signature 336 350 1.1E-32 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS08655 19cd0b51767140e818b3a7e16d71e583 384 SUPERFAMILY SSF48256 6 378 7.72E-107 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS08655 19cd0b51767140e818b3a7e16d71e583 384 PIRSF PIRSF001369 2 382 2.3E-97 T 06-07-2017 IPR024176 Citrate synthase, bacterial-type SMD11_RS08655 19cd0b51767140e818b3a7e16d71e583 384 Pfam PF00285 Citrate synthase, C-terminal domain 10 366 3.9E-102 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 SMD11_RS08655 19cd0b51767140e818b3a7e16d71e583 384 Gene3D G3DSA:1.10.580.10 16 242 1.5E-63 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SMD11_RS08655 19cd0b51767140e818b3a7e16d71e583 384 Gene3D G3DSA:1.10.230.10 243 328 2.7E-22 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 SMD11_RS08655 19cd0b51767140e818b3a7e16d71e583 384 ProSitePatterns PS00480 Citrate synthase signature. 264 276 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 SMD11_RS11280 934827d33986cec471a0632905590365 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 313 9.7E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11280 934827d33986cec471a0632905590365 325 Gene3D G3DSA:1.10.3720.10 32 312 2.4E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11280 934827d33986cec471a0632905590365 325 SUPERFAMILY SSF161098 82 310 1.02E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS10150 a127f8b4f5da38d2a73be13fbaa7d72d 340 Gene3D G3DSA:3.20.20.210 83 337 2.4E-14 T 06-07-2017 SMD11_RS10150 a127f8b4f5da38d2a73be13fbaa7d72d 340 SUPERFAMILY SSF51726 60 336 5.49E-30 T 06-07-2017 SMD11_RS10150 a127f8b4f5da38d2a73be13fbaa7d72d 340 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 14 333 1.0E-13 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD11_RS32965 d02815db14de49549aed0a1e6535c2e1 384 Gene3D G3DSA:3.40.630.10 297 358 8.9E-47 T 06-07-2017 SMD11_RS32965 d02815db14de49549aed0a1e6535c2e1 384 Gene3D G3DSA:3.40.630.10 20 190 8.9E-47 T 06-07-2017 SMD11_RS32965 d02815db14de49549aed0a1e6535c2e1 384 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 76 85 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SMD11_RS32965 d02815db14de49549aed0a1e6535c2e1 384 TIGRFAM TIGR01902 dapE-lys-deAc: N-acetyl-ornithine/N-acetyl-lysine deacetylase 24 356 4.2E-89 T 06-07-2017 IPR010175 Acetyl-ornithine/Acetyl-lysine deacetylase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 SMD11_RS32965 d02815db14de49549aed0a1e6535c2e1 384 SUPERFAMILY SSF53187 274 357 2.86E-48 T 06-07-2017 SMD11_RS32965 d02815db14de49549aed0a1e6535c2e1 384 SUPERFAMILY SSF53187 18 172 2.86E-48 T 06-07-2017 SMD11_RS32965 d02815db14de49549aed0a1e6535c2e1 384 Pfam PF01546 Peptidase family M20/M25/M40 77 354 1.0E-25 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SMD11_RS16320 126dd31733c8492dfd340013c2df214e 566 SUPERFAMILY SSF55874 282 385 1.04E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16320 126dd31733c8492dfd340013c2df214e 566 Pfam PF07730 Histidine kinase 195 258 3.1E-12 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS01325 f362836a85fff676559ed3fc7e303e36 80 SMART SM00823 Phosphopantetheine attachment site 5 76 0.0034 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS01325 f362836a85fff676559ed3fc7e303e36 80 SUPERFAMILY SSF47336 2 78 1.31E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01325 f362836a85fff676559ed3fc7e303e36 80 Pfam PF00550 Phosphopantetheine attachment site 8 72 1.9E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS01325 f362836a85fff676559ed3fc7e303e36 80 Gene3D G3DSA:1.10.1200.10 1 77 1.5E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS33920 10cc90d782deae0e7692f390ab292b18 566 Pfam PF07969 Amidohydrolase family 80 564 1.1E-78 T 06-07-2017 IPR013108 Amidohydrolase 3 SMD11_RS33920 10cc90d782deae0e7692f390ab292b18 566 SUPERFAMILY SSF51338 523 564 2.59E-25 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS33920 10cc90d782deae0e7692f390ab292b18 566 SUPERFAMILY SSF51338 18 92 2.59E-25 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS33920 10cc90d782deae0e7692f390ab292b18 566 SUPERFAMILY SSF51556 91 156 1.02E-17 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS33920 10cc90d782deae0e7692f390ab292b18 566 SUPERFAMILY SSF51556 233 524 1.02E-17 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS33920 10cc90d782deae0e7692f390ab292b18 566 Gene3D G3DSA:3.20.20.140 95 113 5.2E-18 T 06-07-2017 SMD11_RS33920 10cc90d782deae0e7692f390ab292b18 566 Gene3D G3DSA:3.20.20.140 235 513 5.2E-18 T 06-07-2017 SMD11_RS33920 10cc90d782deae0e7692f390ab292b18 566 Gene3D G3DSA:2.30.40.10 33 93 1.8E-18 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS33920 10cc90d782deae0e7692f390ab292b18 566 Gene3D G3DSA:2.30.40.10 523 565 1.8E-18 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS27650 1ef0552a29440f785f9f1b73a2f73e0d 75 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 3 73 14.481 T 06-07-2017 IPR003482 Transcription factor WhiB SMD11_RS27650 1ef0552a29440f785f9f1b73a2f73e0d 75 Pfam PF02467 Transcription factor WhiB 7 68 1.9E-19 T 06-07-2017 IPR003482 Transcription factor WhiB SMD11_RS17240 80e40353b1b9a59e0db6edba2095a9e7 384 SUPERFAMILY SSF52518 32 375 3.87E-100 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS17240 80e40353b1b9a59e0db6edba2095a9e7 384 Gene3D G3DSA:3.40.50.970 26 371 1.9E-132 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS17240 80e40353b1b9a59e0db6edba2095a9e7 384 Pfam PF00676 Dehydrogenase E1 component 63 344 3.8E-81 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 SMD11_RS17240 80e40353b1b9a59e0db6edba2095a9e7 384 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 33 371 9.9E-140 T 06-07-2017 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 SMD11_RS10930 bfac99cb345be18dc00f42e013ba6f64 296 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 78 5.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS10930 bfac99cb345be18dc00f42e013ba6f64 296 SUPERFAMILY SSF46689 25 87 1.18E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS10930 bfac99cb345be18dc00f42e013ba6f64 296 Gene3D G3DSA:1.10.357.10 16 221 1.6E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS09390 86a2443fd3953188d0076c13fa3c68fc 240 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 18 87 1.6E-20 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMD11_RS09390 86a2443fd3953188d0076c13fa3c68fc 240 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 170 233 2.6E-8 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMD11_RS09390 86a2443fd3953188d0076c13fa3c68fc 240 SUPERFAMILY SSF51695 13 237 1.6E-46 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD11_RS09390 86a2443fd3953188d0076c13fa3c68fc 240 Gene3D G3DSA:3.20.20.190 7 238 1.9E-43 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD11_RS31685 9c891a2c22a7af01aacb60ac708782a9 269 Pfam PF05853 beta-keto acid cleavage enzyme 2 109 1.7E-16 T 06-07-2017 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00600+2.3.1.24 SMD11_RS31685 9c891a2c22a7af01aacb60ac708782a9 269 Pfam PF05853 beta-keto acid cleavage enzyme 183 234 2.4E-7 T 06-07-2017 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00600+2.3.1.24 SMD11_RS31685 9c891a2c22a7af01aacb60ac708782a9 269 Gene3D G3DSA:3.20.20.70 2 234 4.4E-36 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS07520 60afa71821d7abe93b2dd89443934dc3 498 Pfam PF13520 Amino acid permease 42 480 2.0E-55 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS07520 60afa71821d7abe93b2dd89443934dc3 498 PIRSF PIRSF006060 18 497 2.1E-93 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS02165 826e3e2dfbdad30943040860fae32fbc 1042 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 635 996 1.8E-56 T 06-07-2017 IPR011749 Conserved hypothetical protein CHP02243 SMD11_RS02165 826e3e2dfbdad30943040860fae32fbc 1042 Pfam PF04865 Baseplate J-like protein 789 945 4.0E-9 T 06-07-2017 IPR006949 Baseplate protein J-like SMD11_RS25245 88c93fac28bab5e7f0141421832ecd47 121 SUPERFAMILY SSF54593 1 115 1.14E-14 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS25245 88c93fac28bab5e7f0141421832ecd47 121 Gene3D G3DSA:3.10.180.10 9 117 9.4E-11 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS09755 5cd06df07eaa2a39a5051eb3d5335f1b 77 SUPERFAMILY SSF54909 2 75 1.05E-14 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS09755 5cd06df07eaa2a39a5051eb3d5335f1b 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 6.7E-13 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS09755 5cd06df07eaa2a39a5051eb3d5335f1b 77 Gene3D G3DSA:3.30.70.920 4 75 9.3E-17 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain SMD11_RS25640 1531f08553ecab78ef4700bea88853e1 268 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 10 253 2.0E-65 T 06-07-2017 SMD11_RS24920 fbececaa9baa87932cc05a1dee43e287 304 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 242 264 3.0E-6 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal SMD11_RS24920 fbececaa9baa87932cc05a1dee43e287 304 SUPERFAMILY SSF52540 17 263 8.04E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24920 fbececaa9baa87932cc05a1dee43e287 304 SMART SM00382 43 241 2.0E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS24920 fbececaa9baa87932cc05a1dee43e287 304 Pfam PF00005 ABC transporter 35 194 1.0E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS24920 fbececaa9baa87932cc05a1dee43e287 304 Gene3D G3DSA:3.40.50.300 15 261 8.1E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS16275 53fdca54492fabe9c994f0a3cdf6752b 286 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 34 277 1.8E-45 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMD11_RS16275 53fdca54492fabe9c994f0a3cdf6752b 286 SUPERFAMILY SSF51695 30 281 2.15E-67 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD11_RS16275 53fdca54492fabe9c994f0a3cdf6752b 286 Gene3D G3DSA:3.20.20.190 21 283 3.6E-78 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD11_RS09265 40ba6e15c164b503799c5307bc89612b 161 Pfam PF14530 Domain of unknown function (DUF4439) 13 143 1.1E-44 T 06-07-2017 IPR029447 Domain of unknown function DUF4439 SMD11_RS09265 40ba6e15c164b503799c5307bc89612b 161 SUPERFAMILY SSF47240 7 143 3.88E-37 T 06-07-2017 IPR009078 Ferritin-like superfamily SMD11_RS09265 40ba6e15c164b503799c5307bc89612b 161 Gene3D G3DSA:1.20.1260.10 9 134 3.0E-43 T 06-07-2017 IPR012347 Ferritin-related SMD11_RS10655 31617c52adbacdd31d8ace1a58a0fa8a 219 Pfam PF07510 Protein of unknown function (DUF1524) 82 213 5.2E-8 T 06-07-2017 IPR011089 Domain of unknown function DUF1524 SMD11_RS24330 4295dfc7ef2fe848542df73ea86b0d83 256 Pfam PF12146 Serine aminopeptidase, S33 159 229 1.7E-7 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 SMD11_RS24330 4295dfc7ef2fe848542df73ea86b0d83 256 Pfam PF12146 Serine aminopeptidase, S33 19 139 2.0E-16 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 SMD11_RS24330 4295dfc7ef2fe848542df73ea86b0d83 256 PIRSF PIRSF017388 1 248 7.4E-74 T 06-07-2017 IPR012354 Esterase/lipase GO:0052689 SMD11_RS24330 4295dfc7ef2fe848542df73ea86b0d83 256 SUPERFAMILY SSF53474 16 246 1.5E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS24330 4295dfc7ef2fe848542df73ea86b0d83 256 Gene3D G3DSA:3.40.50.1820 13 246 5.2E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS06710 a290a47406b1642106747c16d2465489 410 PRINTS PR00359 B-class P450 signature 359 370 1.3E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 PRINTS PR00359 B-class P450 signature 146 162 1.3E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 PRINTS PR00359 B-class P450 signature 201 223 1.3E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 PRINTS PR00359 B-class P450 signature 301 328 1.3E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 PRINTS PR00359 B-class P450 signature 282 293 1.3E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 PRINTS PR00359 B-class P450 signature 329 344 1.3E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 PRINTS PR00359 B-class P450 signature 350 359 1.3E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 PRINTS PR00359 B-class P450 signature 99 110 1.3E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 PRINTS PR00359 B-class P450 signature 163 178 1.3E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 Pfam PF00067 Cytochrome P450 55 379 3.3E-29 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 Gene3D G3DSA:1.10.630.10 20 410 2.4E-127 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 352 361 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 SUPERFAMILY SSF48264 24 410 9.17E-98 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 PRINTS PR00385 P450 superfamily signature 282 293 2.6E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 PRINTS PR00385 P450 superfamily signature 247 264 2.6E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 PRINTS PR00385 P450 superfamily signature 350 359 2.6E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS06710 a290a47406b1642106747c16d2465489 410 PRINTS PR00385 P450 superfamily signature 359 370 2.6E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS15250 46079c0f2771e59e269e13254426cd95 461 Gene3D G3DSA:1.10.150.130 71 170 1.5E-15 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal SMD11_RS15250 46079c0f2771e59e269e13254426cd95 461 Gene3D G3DSA:1.10.443.10 300 425 3.0E-31 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS15250 46079c0f2771e59e269e13254426cd95 461 Gene3D G3DSA:1.10.443.10 177 230 3.0E-31 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS15250 46079c0f2771e59e269e13254426cd95 461 SUPERFAMILY SSF56349 70 240 1.15E-26 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD11_RS15250 46079c0f2771e59e269e13254426cd95 461 Pfam PF00589 Phage integrase family 332 415 9.4E-13 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS15250 46079c0f2771e59e269e13254426cd95 461 SUPERFAMILY SSF56349 300 425 8.83E-27 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD11_RS15250 46079c0f2771e59e269e13254426cd95 461 SUPERFAMILY SSF56349 177 230 8.83E-27 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD11_RS19745 31951b7042427a0d8c51bcb0cde38090 280 Gene3D G3DSA:1.10.260.40 3 66 7.4E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS19745 31951b7042427a0d8c51bcb0cde38090 280 SMART SM00530 15 70 1.3E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS19745 31951b7042427a0d8c51bcb0cde38090 280 Pfam PF13560 Helix-turn-helix domain 11 69 3.1E-11 T 06-07-2017 SMD11_RS19745 31951b7042427a0d8c51bcb0cde38090 280 SUPERFAMILY SSF47413 8 64 1.21E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS25165 cac41b997983275ca940856a8ade6a3c 371 Hamap MF_00493 Transaldolase [tal]. 1 370 164.236 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS25165 cac41b997983275ca940856a8ade6a3c 371 TIGRFAM TIGR00876 tal_mycobact: transaldolase 12 359 9.8E-136 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS25165 cac41b997983275ca940856a8ade6a3c 371 ProSitePatterns PS01054 Transaldolase signature 1. 41 49 - T 06-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 SMD11_RS25165 cac41b997983275ca940856a8ade6a3c 371 Gene3D G3DSA:3.20.20.70 1 359 5.9E-125 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS25165 cac41b997983275ca940856a8ade6a3c 371 Pfam PF00923 Transaldolase 15 359 8.8E-84 T 06-07-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 SMD11_RS25165 cac41b997983275ca940856a8ade6a3c 371 SUPERFAMILY SSF51569 2 359 1.05E-77 T 06-07-2017 SMD11_RS25165 cac41b997983275ca940856a8ade6a3c 371 PIRSF PIRSF036915 1 371 6.1E-180 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SMD11_RS20900 075fd4062e6dd9d38fe1ef84e24ef96e 467 Gene3D G3DSA:2.60.40.10 261 303 7.8E-6 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS20900 075fd4062e6dd9d38fe1ef84e24ef96e 467 SUPERFAMILY SSF160964 46 100 1.44E-6 T 06-07-2017 SMD11_RS20900 075fd4062e6dd9d38fe1ef84e24ef96e 467 SUPERFAMILY SSF161098 319 455 1.38E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS20900 075fd4062e6dd9d38fe1ef84e24ef96e 467 SUPERFAMILY SSF161098 90 179 1.38E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS20900 075fd4062e6dd9d38fe1ef84e24ef96e 467 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 320 455 6.7E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS20900 075fd4062e6dd9d38fe1ef84e24ef96e 467 Gene3D G3DSA:1.10.3720.10 322 458 5.1E-68 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS20900 075fd4062e6dd9d38fe1ef84e24ef96e 467 Gene3D G3DSA:1.10.3720.10 46 172 5.1E-68 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS07275 07e1a901a33961dac14da24490151c17 237 SUPERFAMILY SSF53098 4 205 5.48E-44 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS07275 07e1a901a33961dac14da24490151c17 237 Gene3D G3DSA:3.30.420.10 3 192 2.5E-36 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 SMD11_RS07275 07e1a901a33961dac14da24490151c17 237 Pfam PF00929 Exonuclease 10 182 6.8E-13 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD11_RS07275 07e1a901a33961dac14da24490151c17 237 SMART SM00479 7 192 1.9E-10 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III SMD11_RS02030 dd650fb81b0a0deb193d648eee7f5343 259 Pfam PF13460 NAD(P)H-binding 9 145 2.3E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS02030 dd650fb81b0a0deb193d648eee7f5343 259 Gene3D G3DSA:3.40.50.720 3 213 6.5E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS02030 dd650fb81b0a0deb193d648eee7f5343 259 SUPERFAMILY SSF51735 3 221 8.5E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04785 c5dded32d9e70974cb9afbf11f3c471c 343 PIRSF PIRSF001439 17 342 4.4E-54 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMD11_RS04785 c5dded32d9e70974cb9afbf11f3c471c 343 SUPERFAMILY SSF51735 21 342 5.73E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04785 c5dded32d9e70974cb9afbf11f3c471c 343 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 35 322 1.3E-29 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 SMD11_RS04785 c5dded32d9e70974cb9afbf11f3c471c 343 Gene3D G3DSA:3.30.1780.10 22 159 6.6E-25 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 SMD11_RS04785 c5dded32d9e70974cb9afbf11f3c471c 343 Gene3D G3DSA:3.40.50.720 160 309 1.7E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS14815 5f03fa04963978e0efda58d9ad671c1e 112 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 111 1.0E-41 T 06-07-2017 IPR024412 Lsr2 SMD11_RS14815 5f03fa04963978e0efda58d9ad671c1e 112 Pfam PF11774 Lsr2 2 110 1.5E-40 T 06-07-2017 IPR024412 Lsr2 SMD11_RS04280 6c913ee763db8b466d4a0c9a0c20fa9b 308 Gene3D G3DSA:2.40.10.10 95 176 1.3E-7 T 06-07-2017 SMD11_RS04280 6c913ee763db8b466d4a0c9a0c20fa9b 308 SUPERFAMILY SSF50494 81 285 2.68E-17 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS04280 6c913ee763db8b466d4a0c9a0c20fa9b 308 Pfam PF00089 Trypsin 92 275 1.6E-6 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 SMD11_RS04280 6c913ee763db8b466d4a0c9a0c20fa9b 308 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 113 118 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 SMD11_RS15780 aabe28204f6fc673b47b603fc94a8cea 200 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 4 193 8.1E-97 T 06-07-2017 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD SMD11_RS15780 aabe28204f6fc673b47b603fc94a8cea 200 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 27 191 5.7E-13 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SMD11_RS15780 aabe28204f6fc673b47b603fc94a8cea 200 SUPERFAMILY SSF48150 15 142 3.14E-11 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD11_RS15780 aabe28204f6fc673b47b603fc94a8cea 200 Gene3D G3DSA:1.10.340.30 17 137 9.6E-9 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SMD11_RS20140 553fda74ce90ac64a684fb196b400530 271 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 5 270 43.139 T 06-07-2017 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD11_RS20140 553fda74ce90ac64a684fb196b400530 271 Pfam PF13649 Methyltransferase domain 42 137 3.5E-17 T 06-07-2017 SMD11_RS20140 553fda74ce90ac64a684fb196b400530 271 SUPERFAMILY SSF53335 7 218 7.91E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS20140 553fda74ce90ac64a684fb196b400530 271 Gene3D G3DSA:3.40.50.150 7 182 1.6E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS20140 553fda74ce90ac64a684fb196b400530 271 Gene3D G3DSA:1.10.150.290 194 251 1.5E-25 T 06-07-2017 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD11_RS11905 a526095e6af2aa86dcf18dec5c05f004 379 SMART SM00331 137 358 1.5E-30 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS11905 a526095e6af2aa86dcf18dec5c05f004 379 SUPERFAMILY SSF81606 151 357 4.05E-7 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS11905 a526095e6af2aa86dcf18dec5c05f004 379 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 167 357 3.0E-34 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS21265 2d3cc1bd56bf83a65ff6f7da2dca8bbc 200 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 192 1.2E-51 T 06-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 SMD11_RS21265 2d3cc1bd56bf83a65ff6f7da2dca8bbc 200 SUPERFAMILY SSF52972 1 196 1.99E-65 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like SMD11_RS21265 2d3cc1bd56bf83a65ff6f7da2dca8bbc 200 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 197 47.565 T 06-07-2017 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 SMD11_RS21265 2d3cc1bd56bf83a65ff6f7da2dca8bbc 200 Gene3D G3DSA:3.90.950.10 1 198 5.9E-80 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like SMD11_RS21265 2d3cc1bd56bf83a65ff6f7da2dca8bbc 200 Pfam PF01725 Ham1 family 4 192 2.5E-53 T 06-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 SMD11_RS18650 9916b16db6d80eebae66524c2c7f46f2 450 SUPERFAMILY SSF49785 344 450 7.23E-23 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS18650 9916b16db6d80eebae66524c2c7f46f2 450 Gene3D G3DSA:3.40.630.10 55 329 2.7E-73 T 06-07-2017 SMD11_RS18650 9916b16db6d80eebae66524c2c7f46f2 450 Gene3D G3DSA:2.60.120.260 351 450 8.5E-15 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS18650 9916b16db6d80eebae66524c2c7f46f2 450 Pfam PF04389 Peptidase family M28 118 323 3.2E-44 T 06-07-2017 IPR007484 Peptidase M28 SMD11_RS18650 9916b16db6d80eebae66524c2c7f46f2 450 Pfam PF01483 Proprotein convertase P-domain 371 450 3.3E-19 T 06-07-2017 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 SMD11_RS18650 9916b16db6d80eebae66524c2c7f46f2 450 SUPERFAMILY SSF53187 62 327 2.14E-67 T 06-07-2017 SMD11_RS05560 d38d9197868c14cf862077a8f1f4751a 90 Gene3D G3DSA:1.10.1200.10 4 76 9.7E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS05560 d38d9197868c14cf862077a8f1f4751a 90 SUPERFAMILY SSF47336 3 83 1.28E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS05560 d38d9197868c14cf862077a8f1f4751a 90 Pfam PF00550 Phosphopantetheine attachment site 18 74 1.4E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS05560 d38d9197868c14cf862077a8f1f4751a 90 ProSitePatterns PS00012 Phosphopantetheine attachment site. 33 48 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site SMD11_RS05560 d38d9197868c14cf862077a8f1f4751a 90 SMART SM00823 Phosphopantetheine attachment site 8 78 0.0055 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 SMD11_RS04500 36b2a21e7e5534db0d0be77fece51e6b 74 Pfam PF09489 Probable cobalt transporter subunit (CbtB) 22 74 5.9E-14 T 06-07-2017 IPR012667 Cobalt transporter subunit CbtB, putative SMD11_RS15555 8f6b19587c846ca80c04beb99f50b4aa 154 Pfam PF09424 Yqey-like protein 5 152 7.8E-48 T 06-07-2017 IPR019004 Uncharacterised domain YOR215C, mitochondrial SMD11_RS15555 8f6b19587c846ca80c04beb99f50b4aa 154 Gene3D G3DSA:1.10.10.410 94 153 5.8E-21 T 06-07-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal SMD11_RS15555 8f6b19587c846ca80c04beb99f50b4aa 154 Gene3D G3DSA:1.10.1510.10 3 93 7.2E-27 T 06-07-2017 SMD11_RS15555 8f6b19587c846ca80c04beb99f50b4aa 154 SUPERFAMILY SSF89095 3 152 7.32E-36 T 06-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 SMD11_RS12615 1663e6c9f3454a3e181cd7e7e8221eaf 203 Hamap MF_00528 Septum formation protein Maf [maf]. 9 198 27.842 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 SMD11_RS12615 1663e6c9f3454a3e181cd7e7e8221eaf 203 SUPERFAMILY SSF52972 8 193 3.66E-52 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like SMD11_RS12615 1663e6c9f3454a3e181cd7e7e8221eaf 203 TIGRFAM TIGR00172 maf: septum formation protein Maf 9 191 2.2E-45 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 SMD11_RS12615 1663e6c9f3454a3e181cd7e7e8221eaf 203 PIRSF PIRSF006305 1 200 1.2E-41 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 SMD11_RS12615 1663e6c9f3454a3e181cd7e7e8221eaf 203 Pfam PF02545 Maf-like protein 9 193 1.6E-45 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 SMD11_RS12615 1663e6c9f3454a3e181cd7e7e8221eaf 203 Gene3D G3DSA:3.90.950.10 8 196 1.2E-58 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like SMD11_RS29055 ca30bd918285270556aab7e453632745 753 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 238 406 4.8E-20 T 06-07-2017 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain SMD11_RS29055 ca30bd918285270556aab7e453632745 753 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 496 738 2.5E-12 T 06-07-2017 IPR003776 YcaO-like domain SMD11_RS29730 a506d2eab07d4092368778165ab1548e 473 SUPERFAMILY SSF51735 64 235 7.49E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29730 a506d2eab07d4092368778165ab1548e 473 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 76 200 1.3E-14 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 SMD11_RS29730 a506d2eab07d4092368778165ab1548e 473 Gene3D G3DSA:3.40.50.720 75 258 9.6E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03610 63447320300e14fbd9273aa406fa30fc 143 SUPERFAMILY SSF103196 5 126 9.16E-36 T 06-07-2017 SMD11_RS03610 63447320300e14fbd9273aa406fa30fc 143 SMART SM00960 8 98 4.5E-31 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS03610 63447320300e14fbd9273aa406fa30fc 143 Pfam PF03259 Roadblock/LC7 domain 7 97 3.6E-27 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain SMD11_RS03610 63447320300e14fbd9273aa406fa30fc 143 Gene3D G3DSA:3.30.450.30 5 122 5.4E-28 T 06-07-2017 SMD11_RS05495 0a3aa03a7f0fee1701ba1f23ed7614f7 125 Pfam PF04237 YjbR 19 111 3.5E-18 T 06-07-2017 IPR007351 Uncharacterised protein YjbR SMD11_RS05495 0a3aa03a7f0fee1701ba1f23ed7614f7 125 SUPERFAMILY SSF142906 12 121 1.03E-24 T 06-07-2017 SMD11_RS27750 969b5cc023e9f4968f2f791679716b41 118 Pfam PF13490 Putative zinc-finger 65 101 1.5E-7 T 06-07-2017 IPR027383 Putative zinc-finger SMD11_RS15120 fac8c9dbe8b6d2734cafc1403e33c250 256 SUPERFAMILY SSF53474 4 249 1.07E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15120 fac8c9dbe8b6d2734cafc1403e33c250 256 Gene3D G3DSA:3.40.50.1820 17 126 8.3E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15120 fac8c9dbe8b6d2734cafc1403e33c250 256 Gene3D G3DSA:3.40.50.1820 180 249 8.3E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15120 fac8c9dbe8b6d2734cafc1403e33c250 256 SMART SM00824 Thioesterase 27 250 0.0014 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD11_RS15120 fac8c9dbe8b6d2734cafc1403e33c250 256 Pfam PF00975 Thioesterase domain 25 244 2.8E-38 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS19510 60cba5b70a96bc2e9c9b0c4ceee8542a 487 Gene3D G3DSA:3.20.20.140 168 341 2.5E-17 T 06-07-2017 SMD11_RS19510 60cba5b70a96bc2e9c9b0c4ceee8542a 487 SUPERFAMILY SSF89550 168 374 7.06E-36 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMD11_RS19510 60cba5b70a96bc2e9c9b0c4ceee8542a 487 SMART SM00481 171 235 3.8E-4 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 SMD11_RS15030 0cbe7ca17c8b5fa25642d89251d7e5e8 79 Pfam PF04149 Domain of unknown function (DUF397) 17 69 9.2E-19 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS23465 d4948b774c56a71bc5eeb570084a4915 286 Pfam PF12822 Protein of unknown function (DUF3816) 91 260 2.7E-20 T 06-07-2017 IPR024529 ECF transporter, substrate-specific component GO:0005215 SMD11_RS23465 d4948b774c56a71bc5eeb570084a4915 286 PIRSF PIRSF037395 21 284 4.7E-109 T 06-07-2017 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 SMD11_RS29120 55b7899ede4605c13714314e7cd3a30d 78 Pfam PF04149 Domain of unknown function (DUF397) 27 71 8.8E-9 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS09505 e28f4b4b53a872093d052a560553d0b2 185 SUPERFAMILY SSF55194 3 184 3.27E-66 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 SMD11_RS09505 e28f4b4b53a872093d052a560553d0b2 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.775 T 06-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 SMD11_RS09505 e28f4b4b53a872093d052a560553d0b2 185 Gene3D G3DSA:1.10.132.20 66 185 7.5E-40 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 SMD11_RS09505 e28f4b4b53a872093d052a560553d0b2 185 Pfam PF01765 Ribosome recycling factor 21 183 6.0E-58 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 SMD11_RS09505 e28f4b4b53a872093d052a560553d0b2 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 4.0E-61 T 06-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 SMD11_RS21280 1237a16c6ce1df86076f71daea05cedb 207 Pfam PF13392 HNH endonuclease 161 190 8.4E-7 T 06-07-2017 IPR003615 HNH nuclease SMD11_RS01395 9ffa97892ee88a85c7738bb70b5031e3 327 SUPERFAMILY SSF56601 179 323 9.38E-13 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS01395 9ffa97892ee88a85c7738bb70b5031e3 327 Pfam PF00144 Beta-lactamase 172 306 1.3E-8 T 06-07-2017 IPR001466 Beta-lactamase-related SMD11_RS01395 9ffa97892ee88a85c7738bb70b5031e3 327 Gene3D G3DSA:3.40.710.10 190 325 5.0E-16 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS15375 e317d5706725bf94c798b6204657694c 465 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 28 397 6.2E-97 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 SMD11_RS15375 e317d5706725bf94c798b6204657694c 465 Gene3D G3DSA:1.20.1530.10 23 404 4.4E-138 T 06-07-2017 IPR023171 Na/H antiporter domain SMD11_RS15375 e317d5706725bf94c798b6204657694c 465 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 23 404 20.937 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 SMD11_RS15375 e317d5706725bf94c798b6204657694c 465 Pfam PF06965 Na+/H+ antiporter 1 26 398 9.0E-135 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 SMD11_RS08445 93a3eacdcda28589e8be8139c51bc31e 247 Gene3D G3DSA:3.40.50.150 31 206 2.8E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS08445 93a3eacdcda28589e8be8139c51bc31e 247 SUPERFAMILY SSF53335 31 208 5.92E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS08445 93a3eacdcda28589e8be8139c51bc31e 247 Pfam PF13649 Methyltransferase domain 73 162 1.6E-8 T 06-07-2017 SMD11_RS00235 b655444c6c2947b6fdc36f052f9da395 259 SUPERFAMILY SSF53474 4 253 1.1E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS00235 b655444c6c2947b6fdc36f052f9da395 259 Gene3D G3DSA:3.40.50.1820 3 254 2.7E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS00235 b655444c6c2947b6fdc36f052f9da395 259 Pfam PF12697 Alpha/beta hydrolase family 28 248 4.5E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS00235 b655444c6c2947b6fdc36f052f9da395 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 1.5E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS00235 b655444c6c2947b6fdc36f052f9da395 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 1.5E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS00235 b655444c6c2947b6fdc36f052f9da395 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 1.5E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS00235 b655444c6c2947b6fdc36f052f9da395 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 1.5E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS11110 417de43fdd8c88a5c559c6dcd97df4a7 214 SUPERFAMILY SSF160904 8 182 1.01E-36 T 06-07-2017 SMD11_RS11110 417de43fdd8c88a5c559c6dcd97df4a7 214 Pfam PF11706 CGNR zinc finger 141 183 4.5E-15 T 06-07-2017 IPR021005 Zinc finger, CGNR SMD11_RS11110 417de43fdd8c88a5c559c6dcd97df4a7 214 Gene3D G3DSA:1.10.3300.10 8 184 4.3E-44 T 06-07-2017 IPR023286 ABATE domain SMD11_RS11110 417de43fdd8c88a5c559c6dcd97df4a7 214 Pfam PF07336 Putative stress-induced transcription regulator 9 119 6.0E-14 T 06-07-2017 IPR010852 Putative stress-induced transcription regulator SMD11_RS17015 67dfab7236f0e7f8c69b42c29a64bb69 212 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 5 188 1.2E-60 T 06-07-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD11_RS17015 67dfab7236f0e7f8c69b42c29a64bb69 212 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 4.6E-9 T 06-07-2017 SMD11_RS17015 67dfab7236f0e7f8c69b42c29a64bb69 212 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 77 93 4.6E-9 T 06-07-2017 SMD11_RS17015 67dfab7236f0e7f8c69b42c29a64bb69 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 167 180 9.3E-13 T 06-07-2017 SMD11_RS17015 67dfab7236f0e7f8c69b42c29a64bb69 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 9.3E-13 T 06-07-2017 SMD11_RS17015 67dfab7236f0e7f8c69b42c29a64bb69 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 9.3E-13 T 06-07-2017 SMD11_RS17015 67dfab7236f0e7f8c69b42c29a64bb69 212 SUPERFAMILY SSF52317 4 191 1.2E-56 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS17015 67dfab7236f0e7f8c69b42c29a64bb69 212 PRINTS PR00097 Anthranilate synthase component II signature 122 134 2.8E-33 T 06-07-2017 SMD11_RS17015 67dfab7236f0e7f8c69b42c29a64bb69 212 PRINTS PR00097 Anthranilate synthase component II signature 49 58 2.8E-33 T 06-07-2017 SMD11_RS17015 67dfab7236f0e7f8c69b42c29a64bb69 212 PRINTS PR00097 Anthranilate synthase component II signature 5 19 2.8E-33 T 06-07-2017 SMD11_RS17015 67dfab7236f0e7f8c69b42c29a64bb69 212 PRINTS PR00097 Anthranilate synthase component II signature 102 110 2.8E-33 T 06-07-2017 SMD11_RS17015 67dfab7236f0e7f8c69b42c29a64bb69 212 PRINTS PR00097 Anthranilate synthase component II signature 77 88 2.8E-33 T 06-07-2017 SMD11_RS17015 67dfab7236f0e7f8c69b42c29a64bb69 212 PRINTS PR00097 Anthranilate synthase component II signature 167 180 2.8E-33 T 06-07-2017 SMD11_RS17015 67dfab7236f0e7f8c69b42c29a64bb69 212 Gene3D G3DSA:3.40.50.880 4 191 3.3E-65 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS17015 67dfab7236f0e7f8c69b42c29a64bb69 212 Pfam PF00117 Glutamine amidotransferase class-I 7 189 4.8E-52 T 06-07-2017 IPR017926 Glutamine amidotransferase SMD11_RS04915 917ca491e48f4d0899ce81eab439f33e 201 SMART SM00382 15 146 8.4E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS04915 917ca491e48f4d0899ce81eab439f33e 201 SUPERFAMILY SSF52540 16 138 8.85E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS04915 917ca491e48f4d0899ce81eab439f33e 201 Gene3D G3DSA:3.40.50.300 10 52 1.4E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS32855 c8f7bd00b17c13d5a10e1c0c4a617f98 286 SUPERFAMILY SSF109854 14 170 2.29E-12 T 06-07-2017 SMD11_RS32855 c8f7bd00b17c13d5a10e1c0c4a617f98 286 SUPERFAMILY SSF55718 195 278 8.24E-8 T 06-07-2017 IPR003033 SCP2 sterol-binding domain SMD11_RS32855 c8f7bd00b17c13d5a10e1c0c4a617f98 286 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 22 164 5.3E-9 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD11_RS34210 3adabf68f3ae7bcb782b092d39ead94f 589 Pfam PF12796 Ankyrin repeats (3 copies) 502 585 3.4E-11 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain SMD11_RS34210 3adabf68f3ae7bcb782b092d39ead94f 589 SUPERFAMILY SSF56601 164 469 9.56E-105 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS34210 3adabf68f3ae7bcb782b092d39ead94f 589 TIGRFAM TIGR03814 Gln_ase: glutaminase A 169 465 1.6E-94 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 SMD11_RS34210 3adabf68f3ae7bcb782b092d39ead94f 589 Gene3D G3DSA:1.25.40.20 500 586 4.2E-20 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain SMD11_RS34210 3adabf68f3ae7bcb782b092d39ead94f 589 Pfam PF04960 Glutaminase 182 468 4.0E-113 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 SMD11_RS34210 3adabf68f3ae7bcb782b092d39ead94f 589 Gene3D G3DSA:3.40.710.10 160 469 2.0E-127 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS34210 3adabf68f3ae7bcb782b092d39ead94f 589 Hamap MF_00313 Glutaminase [glsA]. 165 468 36.859 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 SMD11_RS34210 3adabf68f3ae7bcb782b092d39ead94f 589 SMART SM00248 530 559 2.3E-5 T 06-07-2017 IPR002110 Ankyrin repeat GO:0005515 SMD11_RS34210 3adabf68f3ae7bcb782b092d39ead94f 589 SUPERFAMILY SSF48403 496 585 2.02E-19 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain SMD11_RS05975 1f1fdcdb4194409a16f3a160ce635ac7 254 Pfam PF12705 PD-(D/E)XK nuclease superfamily 4 250 9.5E-25 T 06-07-2017 SMD11_RS20300 5db2f8c1688368433aeedfccdc7014df 156 Pfam PF04977 Septum formation initiator 45 122 3.0E-14 T 06-07-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 SMD11_RS31945 4ac28734a4bb55361e878ef31e373282 270 SUPERFAMILY SSF51735 4 257 1.13E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS31945 4ac28734a4bb55361e878ef31e373282 270 Pfam PF13460 NAD(P)H-binding 8 166 5.5E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS31945 4ac28734a4bb55361e878ef31e373282 270 Gene3D G3DSA:3.40.50.720 2 200 8.5E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS24595 8f2ef1deb44d0639573f8e25addf5990 367 Gene3D G3DSA:2.30.30.60 193 241 2.2E-11 T 06-07-2017 SMD11_RS24595 8f2ef1deb44d0639573f8e25addf5990 367 SUPERFAMILY SSF50182 177 242 8.17E-16 T 06-07-2017 IPR010920 LSM domain SMD11_RS24595 8f2ef1deb44d0639573f8e25addf5990 367 Pfam PF00924 Mechanosensitive ion channel 137 326 1.5E-29 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 Gene3D G3DSA:1.20.1250.20 38 220 1.8E-29 T 06-07-2017 SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 SUPERFAMILY SSF49464 549 626 2.0E-9 T 06-07-2017 IPR008969 Carboxypeptidase-like, regulatory domain SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 SUPERFAMILY SSF103473 273 445 1.7E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 SUPERFAMILY SSF103473 22 221 1.7E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 SUPERFAMILY SSF103473 488 515 1.7E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 SUPERFAMILY SSF49452 626 710 6.67E-13 T 06-07-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 Gene3D G3DSA:2.60.40.10 717 770 1.6E-11 T 06-07-2017 IPR013783 Immunoglobulin-like fold SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 Pfam PF07690 Major Facilitator Superfamily 43 436 1.6E-51 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 39 448 3.7E-79 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 Pfam PF13620 Carboxypeptidase regulatory-like domain 716 792 1.5E-11 T 06-07-2017 SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 Pfam PF13620 Carboxypeptidase regulatory-like domain 549 626 5.1E-10 T 06-07-2017 SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 Pfam PF13620 Carboxypeptidase regulatory-like domain 632 710 1.7E-15 T 06-07-2017 SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 Gene3D G3DSA:2.60.40.1120 632 714 3.1E-14 T 06-07-2017 IPR014766 Carboxypeptidase, regulatory domain SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 Gene3D G3DSA:2.60.40.1120 549 626 2.7E-8 T 06-07-2017 IPR014766 Carboxypeptidase, regulatory domain SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 Gene3D G3DSA:1.20.1250.20 494 517 1.3E-21 T 06-07-2017 SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 Gene3D G3DSA:1.20.1250.20 288 451 1.3E-21 T 06-07-2017 SMD11_RS06465 2fbf7b325404e25022797e487d2a5118 796 SUPERFAMILY SSF49478 717 784 3.45E-10 T 06-07-2017 SMD11_RS04380 1a4b217e00ce82007de0c477c3cfa800 116 Pfam PF03777 Small secreted domain (DUF320) 24 79 9.3E-27 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD11_RS08475 879f7e6a7e89478d1da6e6b7c376373f 149 Gene3D G3DSA:2.40.50.140 60 143 1.8E-8 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold SMD11_RS08475 879f7e6a7e89478d1da6e6b7c376373f 149 PIRSF PIRSF006910 4 146 1.2E-54 T 06-07-2017 IPR016499 Nucleic acid binding protein, Rv2694c, predicted SMD11_RS02715 5379b5687859c9d426eb4a24a24ae1ce 783 Pfam PF01752 Collagenase 366 642 1.4E-50 T 06-07-2017 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 SMD11_RS02715 5379b5687859c9d426eb4a24a24ae1ce 783 Pfam PF08453 Peptidase family M9 N-terminal 137 274 7.5E-9 T 06-07-2017 IPR013661 Peptidase M9, collagenase, N-terminal domain SMD11_RS02715 5379b5687859c9d426eb4a24a24ae1ce 783 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 474 490 3.7E-16 T 06-07-2017 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 SMD11_RS02715 5379b5687859c9d426eb4a24a24ae1ce 783 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 512 530 3.7E-16 T 06-07-2017 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 SMD11_RS02715 5379b5687859c9d426eb4a24a24ae1ce 783 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 538 553 3.7E-16 T 06-07-2017 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 SMD11_RS02715 5379b5687859c9d426eb4a24a24ae1ce 783 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 456 470 3.7E-16 T 06-07-2017 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 SMD11_RS26690 da5d3555ebb59e73fefa481a0bd0051f 243 Pfam PF07179 SseB protein N-terminal domain 21 142 5.2E-32 T 06-07-2017 IPR009839 SseB protein N-terminal domain SMD11_RS01930 fe545b33331a9f549edaf9a0f8e0f278 206 Gene3D G3DSA:2.30.110.10 39 161 2.1E-25 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS01930 fe545b33331a9f549edaf9a0f8e0f278 206 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 41 130 3.9E-11 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SMD11_RS01930 fe545b33331a9f549edaf9a0f8e0f278 206 SUPERFAMILY SSF50475 40 161 7.86E-15 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS29960 96881d98a10f672f72044467568a8475 93 SUPERFAMILY SSF47336 5 82 8.51E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS29960 96881d98a10f672f72044467568a8475 93 Gene3D G3DSA:1.10.1200.10 2 78 2.5E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain SMD11_RS24230 9227354bcd90a99bc5ab6940c3e1e77d 541 Gene3D G3DSA:1.20.810.10 19 440 5.8E-91 T 06-07-2017 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 SMD11_RS24230 9227354bcd90a99bc5ab6940c3e1e77d 541 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 120 293 7.8E-59 T 06-07-2017 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 SMD11_RS24230 9227354bcd90a99bc5ab6940c3e1e77d 541 SUPERFAMILY SSF81342 19 296 3.77E-63 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 SMD11_RS03905 0dff19698f46dfe8bd44195cc2c764b3 265 Pfam PF08223 PaaX-like protein C-terminal domain 108 256 3.2E-15 T 06-07-2017 IPR013225 PaaX-like, C-terminal SMD11_RS03905 0dff19698f46dfe8bd44195cc2c764b3 265 Pfam PF07848 PaaX-like protein 30 90 2.9E-13 T 06-07-2017 IPR012906 PaaX-like, N-terminal SMD11_RS25035 e52c6050fa5f2ecf6cdd09594bbd993e 192 Pfam PF02342 TerD domain 2 179 3.2E-43 T 06-07-2017 IPR003325 TerD domain GO:0006950 SMD11_RS25035 e52c6050fa5f2ecf6cdd09594bbd993e 192 Gene3D G3DSA:2.60.60.30 21 181 6.3E-46 T 06-07-2017 SMD11_RS06600 da73ab7785fc38424c59457b1503a3e3 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 123 142 8.5E-24 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS06600 da73ab7785fc38424c59457b1503a3e3 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 405 423 8.5E-24 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS06600 da73ab7785fc38424c59457b1503a3e3 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 105 123 8.5E-24 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS06600 da73ab7785fc38424c59457b1503a3e3 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 459 474 8.5E-24 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS06600 da73ab7785fc38424c59457b1503a3e3 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 35 60 8.5E-24 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS06600 da73ab7785fc38424c59457b1503a3e3 601 SUPERFAMILY SSF56235 2 362 1.27E-126 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS06600 da73ab7785fc38424c59457b1503a3e3 601 SUPERFAMILY SSF56235 400 600 1.27E-126 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal SMD11_RS06600 da73ab7785fc38424c59457b1503a3e3 601 Pfam PF01019 Gamma-glutamyltranspeptidase 28 593 3.4E-113 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 SMD11_RS12765 601079396ad92fab0de183e687ebd80b 328 SUPERFAMILY SSF55729 135 322 4.22E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS12765 601079396ad92fab0de183e687ebd80b 328 Gene3D G3DSA:3.40.630.30 175 319 8.9E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS12765 601079396ad92fab0de183e687ebd80b 328 Gene3D G3DSA:3.40.630.30 6 150 5.3E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS12765 601079396ad92fab0de183e687ebd80b 328 Pfam PF00583 Acetyltransferase (GNAT) family 250 313 5.0E-9 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS12765 601079396ad92fab0de183e687ebd80b 328 Pfam PF00583 Acetyltransferase (GNAT) family 62 147 5.1E-6 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS12765 601079396ad92fab0de183e687ebd80b 328 SUPERFAMILY SSF55729 5 149 6.52E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS16725 cd3b7337449cb02d60f96a5ec4995f16 428 Pfam PF13360 PQQ-like domain 101 388 2.7E-6 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat SMD11_RS16725 cd3b7337449cb02d60f96a5ec4995f16 428 Gene3D G3DSA:2.140.10.10 91 247 2.6E-7 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain SMD11_RS16725 cd3b7337449cb02d60f96a5ec4995f16 428 Gene3D G3DSA:2.140.10.10 294 388 2.6E-7 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain SMD11_RS16725 cd3b7337449cb02d60f96a5ec4995f16 428 SUPERFAMILY SSF50998 103 386 6.54E-10 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD11_RS14510 f6f4854b78189358ea5dec5446610564 154 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 137 1.1E-16 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase SMD11_RS14510 f6f4854b78189358ea5dec5446610564 154 SUPERFAMILY SSF55961 4 143 6.75E-20 T 06-07-2017 SMD11_RS14510 f6f4854b78189358ea5dec5446610564 154 Gene3D G3DSA:3.30.530.20 3 142 4.2E-12 T 06-07-2017 IPR023393 START-like domain SMD11_RS23120 86686cb2c5678ce14c84117649c2b677 266 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 10 229 1.9E-30 T 06-07-2017 SMD11_RS20660 af7b9ce6812a5683c7e5dd3efa4c7e39 360 Pfam PF00483 Nucleotidyl transferase 4 236 5.6E-46 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SMD11_RS20660 af7b9ce6812a5683c7e5dd3efa4c7e39 360 SUPERFAMILY SSF53448 4 242 3.29E-68 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20660 af7b9ce6812a5683c7e5dd3efa4c7e39 360 SUPERFAMILY SSF53448 270 311 3.29E-68 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20660 af7b9ce6812a5683c7e5dd3efa4c7e39 360 Gene3D G3DSA:3.90.550.10 2 238 1.5E-65 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20660 af7b9ce6812a5683c7e5dd3efa4c7e39 360 Gene3D G3DSA:2.160.10.10 258 353 2.3E-15 T 06-07-2017 SMD11_RS13670 b2db7b7312d2e1b9966dc97e617fe4b9 328 SUPERFAMILY SSF51679 7 326 4.97E-67 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS13670 b2db7b7312d2e1b9966dc97e617fe4b9 328 Pfam PF00296 Luciferase-like monooxygenase 9 293 2.0E-59 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS13670 b2db7b7312d2e1b9966dc97e617fe4b9 328 Gene3D G3DSA:3.20.20.30 4 325 8.7E-74 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS11730 bf3dcd2d8baa598f6af0dcc9ac769352 290 SUPERFAMILY SSF53474 25 287 2.36E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS11730 bf3dcd2d8baa598f6af0dcc9ac769352 290 Pfam PF12697 Alpha/beta hydrolase family 41 280 1.2E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS11730 bf3dcd2d8baa598f6af0dcc9ac769352 290 Gene3D G3DSA:3.40.50.1820 26 288 1.8E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01845 bd1859144180b1d6172a650f3bf0f8dd 288 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 15 285 7.1E-34 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF SMD11_RS01845 bd1859144180b1d6172a650f3bf0f8dd 288 SUPERFAMILY SSF47240 105 220 5.62E-10 T 06-07-2017 IPR009078 Ferritin-like superfamily SMD11_RS16420 8eba1a0f6498898c971840d10c04f421 246 Pfam PF07987 Domain of unkown function (DUF1775) 32 177 1.4E-50 T 06-07-2017 IPR012533 GLE1, N-terminal, bacteria SMD11_RS34485 d1ad12a705ba9e617af66d8d1d85e7d9 231 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 61 153 1.4E-13 T 06-07-2017 IPR012912 Plasmid pRiA4b, Orf3 SMD11_RS34485 d1ad12a705ba9e617af66d8d1d85e7d9 231 Gene3D G3DSA:3.10.290.30 42 179 9.2E-21 T 06-07-2017 IPR024047 Protein MM3350-like domain SMD11_RS34485 d1ad12a705ba9e617af66d8d1d85e7d9 231 SUPERFAMILY SSF159941 39 191 5.89E-23 T 06-07-2017 IPR024047 Protein MM3350-like domain SMD11_RS18505 e614cbde48dfbcb3f3e9c6412504f211 148 Gene3D G3DSA:2.30.40.10 17 62 1.6E-5 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS18505 e614cbde48dfbcb3f3e9c6412504f211 148 SUPERFAMILY SSF51338 2 62 4.32E-14 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS01955 00c147dce83cfd6ced88d01b48264d48 491 Pfam PF02652 L-lactate permease 341 471 1.8E-11 T 06-07-2017 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 SMD11_RS02500 b701bad593f61ff660517b740f9af0f4 391 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 193 230 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS02500 b701bad593f61ff660517b740f9af0f4 391 Pfam PF00202 Aminotransferase class-III 4 375 4.2E-79 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 SMD11_RS02500 b701bad593f61ff660517b740f9af0f4 391 Gene3D G3DSA:3.90.1150.10 265 379 2.4E-27 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SMD11_RS02500 b701bad593f61ff660517b740f9af0f4 391 Gene3D G3DSA:3.40.640.10 33 264 4.4E-76 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS02500 b701bad593f61ff660517b740f9af0f4 391 SUPERFAMILY SSF53383 4 377 5.31E-97 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS10160 886a319de5fee3c7cae4dc40a479cb9f 179 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 151 2.0E-32 T 06-07-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG SMD11_RS10160 886a319de5fee3c7cae4dc40a479cb9f 179 SUPERFAMILY SSF102405 1 173 4.88E-41 T 06-07-2017 SMD11_RS10160 886a319de5fee3c7cae4dc40a479cb9f 179 Gene3D G3DSA:3.40.50.450 2 174 1.3E-41 T 06-07-2017 SMD11_RS10160 886a319de5fee3c7cae4dc40a479cb9f 179 Pfam PF03641 Possible lysine decarboxylase 44 170 2.4E-28 T 06-07-2017 IPR031100 LOG family SMD11_RS05500 c16c548ff23da0a3a443cbfc5da9a1a8 319 SMART SM01130 14 317 5.0E-78 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS05500 c16c548ff23da0a3a443cbfc5da9a1a8 319 PRINTS PR00146 Dihydrodipicolinate synthase signature 141 158 4.8E-10 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS05500 c16c548ff23da0a3a443cbfc5da9a1a8 319 PRINTS PR00146 Dihydrodipicolinate synthase signature 48 69 4.8E-10 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS05500 c16c548ff23da0a3a443cbfc5da9a1a8 319 PRINTS PR00146 Dihydrodipicolinate synthase signature 84 102 4.8E-10 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS05500 c16c548ff23da0a3a443cbfc5da9a1a8 319 PRINTS PR00146 Dihydrodipicolinate synthase signature 116 132 4.8E-10 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS05500 c16c548ff23da0a3a443cbfc5da9a1a8 319 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 146 176 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SMD11_RS05500 c16c548ff23da0a3a443cbfc5da9a1a8 319 Gene3D G3DSA:3.20.20.70 14 319 7.5E-82 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS05500 c16c548ff23da0a3a443cbfc5da9a1a8 319 PIRSF PIRSF001365 13 319 4.3E-76 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS05500 c16c548ff23da0a3a443cbfc5da9a1a8 319 Pfam PF00701 Dihydrodipicolinate synthetase family 15 310 1.0E-49 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS05500 c16c548ff23da0a3a443cbfc5da9a1a8 319 SUPERFAMILY SSF51569 15 319 1.05E-72 T 06-07-2017 SMD11_RS17175 382ce8a055633f2274fa95b678fefdf5 355 Gene3D G3DSA:3.40.50.970 11 200 2.6E-73 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS17175 382ce8a055633f2274fa95b678fefdf5 355 SMART SM00861 13 188 1.1E-67 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS17175 382ce8a055633f2274fa95b678fefdf5 355 SUPERFAMILY SSF52518 12 198 2.56E-67 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold SMD11_RS17175 382ce8a055633f2274fa95b678fefdf5 355 Gene3D G3DSA:3.40.50.920 208 329 1.3E-41 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS17175 382ce8a055633f2274fa95b678fefdf5 355 SUPERFAMILY SSF52922 202 331 2.22E-38 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SMD11_RS17175 382ce8a055633f2274fa95b678fefdf5 355 Pfam PF02779 Transketolase, pyrimidine binding domain 13 186 3.2E-46 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain SMD11_RS17175 382ce8a055633f2274fa95b678fefdf5 355 Pfam PF02780 Transketolase, C-terminal domain 204 325 1.5E-38 T 06-07-2017 IPR033248 Transketolase, C-terminal domain SMD11_RS06365 325d5a271fb3f2e3d5578ed4ea14cfa5 210 PRINTS PR01398 Isochorismatase signature 63 80 1.4E-45 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS06365 325d5a271fb3f2e3d5578ed4ea14cfa5 210 PRINTS PR01398 Isochorismatase signature 2 14 1.4E-45 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS06365 325d5a271fb3f2e3d5578ed4ea14cfa5 210 PRINTS PR01398 Isochorismatase signature 80 99 1.4E-45 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS06365 325d5a271fb3f2e3d5578ed4ea14cfa5 210 PRINTS PR01398 Isochorismatase signature 186 203 1.4E-45 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS06365 325d5a271fb3f2e3d5578ed4ea14cfa5 210 PRINTS PR01398 Isochorismatase signature 112 134 1.4E-45 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS06365 325d5a271fb3f2e3d5578ed4ea14cfa5 210 PRINTS PR01398 Isochorismatase signature 168 186 1.4E-45 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS06365 325d5a271fb3f2e3d5578ed4ea14cfa5 210 Gene3D G3DSA:3.40.50.850 1 207 1.1E-60 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS06365 325d5a271fb3f2e3d5578ed4ea14cfa5 210 PIRSF PIRSF001111 1 210 6.7E-95 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 SMD11_RS06365 325d5a271fb3f2e3d5578ed4ea14cfa5 210 SUPERFAMILY SSF52499 1 206 6.54E-61 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS06365 325d5a271fb3f2e3d5578ed4ea14cfa5 210 Pfam PF00857 Isochorismatase family 32 204 9.6E-35 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SMD11_RS11775 a646d3dcdafceffe6b1541122b4a6978 310 Pfam PF00892 EamA-like transporter family 162 295 5.5E-8 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS11775 a646d3dcdafceffe6b1541122b4a6978 310 SUPERFAMILY SSF103481 198 301 1.7E-10 T 06-07-2017 SMD11_RS11775 a646d3dcdafceffe6b1541122b4a6978 310 SUPERFAMILY SSF103481 50 149 3.92E-8 T 06-07-2017 SMD11_RS23325 353cd0748be0bd5ed84034435a39fd20 75 SMART SM00834 1 42 6.5E-15 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMD11_RS23325 353cd0748be0bd5ed84034435a39fd20 75 Pfam PF09723 Zinc ribbon domain 1 40 8.1E-13 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMD11_RS23325 353cd0748be0bd5ed84034435a39fd20 75 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 49 3.1E-16 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain SMD11_RS05765 00988ee0022361dbee7a2bd1b9eadbe2 315 SUPERFAMILY SSF50129 2 145 5.02E-25 T 06-07-2017 IPR011032 GroES-like SMD11_RS05765 00988ee0022361dbee7a2bd1b9eadbe2 315 Gene3D G3DSA:3.40.50.720 141 255 3.1E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05765 00988ee0022361dbee7a2bd1b9eadbe2 315 Pfam PF00107 Zinc-binding dehydrogenase 147 259 4.5E-20 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SMD11_RS05765 00988ee0022361dbee7a2bd1b9eadbe2 315 SUPERFAMILY SSF51735 112 286 1.07E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS05765 00988ee0022361dbee7a2bd1b9eadbe2 315 SMART SM00829 10 312 2.8E-13 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SMD11_RS05765 00988ee0022361dbee7a2bd1b9eadbe2 315 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 83 1.5E-5 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SMD11_RS05765 00988ee0022361dbee7a2bd1b9eadbe2 315 Gene3D G3DSA:3.90.180.10 3 140 1.0E-28 T 06-07-2017 IPR011032 GroES-like SMD11_RS12900 42901f3825fe0285cf257eeb0f388f08 180 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 22 175 1.9E-55 T 06-07-2017 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 SMD11_RS12900 42901f3825fe0285cf257eeb0f388f08 180 SUPERFAMILY SSF52540 17 178 7.22E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12900 42901f3825fe0285cf257eeb0f388f08 180 Pfam PF01202 Shikimate kinase 26 133 6.0E-10 T 06-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SMD11_RS12900 42901f3825fe0285cf257eeb0f388f08 180 Gene3D G3DSA:3.40.50.300 17 178 4.1E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS32535 132d8d848e5736344edfad960f19fa04 251 SUPERFAMILY SSF52317 35 239 8.6E-32 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS32535 132d8d848e5736344edfad960f19fa04 251 Pfam PF07722 Peptidase C26 9 221 1.3E-51 T 06-07-2017 IPR011697 Peptidase C26 GO:0006541|GO:0016787 SMD11_RS32535 132d8d848e5736344edfad960f19fa04 251 Gene3D G3DSA:3.40.50.880 7 237 2.2E-36 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS26885 dba5b9ad359e0b81e904bdff81ca5995 301 SUPERFAMILY SSF103481 40 132 2.22E-8 T 06-07-2017 SMD11_RS26885 dba5b9ad359e0b81e904bdff81ca5995 301 SUPERFAMILY SSF103481 177 279 1.02E-10 T 06-07-2017 SMD11_RS26885 dba5b9ad359e0b81e904bdff81ca5995 301 Pfam PF00892 EamA-like transporter family 3 126 4.7E-11 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS26885 dba5b9ad359e0b81e904bdff81ca5995 301 Pfam PF00892 EamA-like transporter family 141 272 1.3E-14 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS29585 ae2784f30781601f3ae01da4d83a1dd2 303 SUPERFAMILY SSF56112 25 275 1.25E-46 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS29585 ae2784f30781601f3ae01da4d83a1dd2 303 Pfam PF01636 Phosphotransferase enzyme family 40 267 1.4E-34 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase SMD11_RS29585 ae2784f30781601f3ae01da4d83a1dd2 303 Gene3D G3DSA:3.90.1200.10 111 275 2.4E-32 T 06-07-2017 SMD11_RS04650 b9be71c8c20cdc174bb96e85ec44d356 246 Pfam PF10014 2OG-Fe dioxygenase 52 240 1.8E-49 T 06-07-2017 IPR018724 2OG-Fe dioxygenase SMD11_RS07920 71c647a6c864ddca6784c15ab9d90b78 284 Pfam PF07848 PaaX-like protein 10 83 4.9E-15 T 06-07-2017 IPR012906 PaaX-like, N-terminal SMD11_RS07920 71c647a6c864ddca6784c15ab9d90b78 284 PIRSF PIRSF020623 1 282 7.2E-82 T 06-07-2017 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 SMD11_RS07920 71c647a6c864ddca6784c15ab9d90b78 284 Gene3D G3DSA:1.10.10.10 41 87 3.7E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07920 71c647a6c864ddca6784c15ab9d90b78 284 Pfam PF08223 PaaX-like protein C-terminal domain 105 267 2.7E-48 T 06-07-2017 IPR013225 PaaX-like, C-terminal SMD11_RS12245 fa888a1d6c5a97a68eab3303c34b9c9e 243 SUPERFAMILY SSF53955 170 237 1.05E-8 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS12245 fa888a1d6c5a97a68eab3303c34b9c9e 243 Pfam PF01464 Transglycosylase SLT domain 166 232 1.7E-6 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 SMD11_RS12245 fa888a1d6c5a97a68eab3303c34b9c9e 243 Gene3D G3DSA:1.10.530.10 170 236 1.7E-6 T 06-07-2017 SMD11_RS21090 784e4473441acaadbef5ab3ec67c87a0 296 Pfam PF00561 alpha/beta hydrolase fold 35 278 5.8E-20 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS21090 784e4473441acaadbef5ab3ec67c87a0 296 SUPERFAMILY SSF53474 15 295 3.31E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS21090 784e4473441acaadbef5ab3ec67c87a0 296 Gene3D G3DSA:3.40.50.1820 15 295 1.1E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS33630 72d227298412c35c7a194254ff67e652 248 SUPERFAMILY SSF53474 2 245 1.4E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS33630 72d227298412c35c7a194254ff67e652 248 Gene3D G3DSA:3.40.50.1820 3 242 9.7E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS33630 72d227298412c35c7a194254ff67e652 248 Pfam PF01738 Dienelactone hydrolase family 16 243 4.4E-40 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 SMD11_RS03665 56cbbe969335745cba1c8f690b72596d 289 Gene3D G3DSA:2.60.40.1120 30 107 5.2E-10 T 06-07-2017 IPR014766 Carboxypeptidase, regulatory domain SMD11_RS03665 56cbbe969335745cba1c8f690b72596d 289 Pfam PF13620 Carboxypeptidase regulatory-like domain 31 101 4.1E-10 T 06-07-2017 SMD11_RS03665 56cbbe969335745cba1c8f690b72596d 289 SUPERFAMILY SSF101874 117 287 1.31E-45 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS03665 56cbbe969335745cba1c8f690b72596d 289 SMART SM00867 118 286 3.2E-49 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS03665 56cbbe969335745cba1c8f690b72596d 289 SUPERFAMILY SSF49464 30 103 2.82E-9 T 06-07-2017 IPR008969 Carboxypeptidase-like, regulatory domain SMD11_RS03665 56cbbe969335745cba1c8f690b72596d 289 Gene3D G3DSA:2.40.128.110 118 288 7.6E-50 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS03665 56cbbe969335745cba1c8f690b72596d 289 Pfam PF04264 YceI-like domain 119 285 6.2E-35 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like SMD11_RS32205 390c68aff6379edc02e501cf7df8cd7d 150 Pfam PF01638 HxlR-like helix-turn-helix 21 104 1.9E-19 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type SMD11_RS32205 390c68aff6379edc02e501cf7df8cd7d 150 Gene3D G3DSA:1.10.10.10 2 110 1.4E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS32205 390c68aff6379edc02e501cf7df8cd7d 150 SUPERFAMILY SSF46785 7 144 1.18E-39 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02640 0cfa9096562029d31632b39dd522d431 399 SUPERFAMILY SSF56281 206 306 1.55E-12 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS02640 0cfa9096562029d31632b39dd522d431 399 SUPERFAMILY SSF56281 2 157 1.55E-12 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS02640 0cfa9096562029d31632b39dd522d431 399 Gene3D G3DSA:3.60.15.10 9 168 1.3E-7 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS02640 0cfa9096562029d31632b39dd522d431 399 Gene3D G3DSA:3.60.15.10 205 286 1.3E-7 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS10550 1d54a3a24ccd20e2a0338e752d30a243 126 Pfam PF06236 Tyrosinase co-factor MelC1 15 126 1.0E-25 T 06-07-2017 IPR010928 Tyrosinase co-factor MelC1 GO:0005507|GO:0042438 SMD11_RS11250 9c48ae56e3631a21658724168c9b40ed 85 Pfam PF02467 Transcription factor WhiB 3 71 1.6E-27 T 06-07-2017 IPR003482 Transcription factor WhiB SMD11_RS11250 9c48ae56e3631a21658724168c9b40ed 85 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 19.15 T 06-07-2017 IPR003482 Transcription factor WhiB SMD11_RS08365 14422b87ac69e7a257d978ca6f9e03d1 658 SUPERFAMILY SSF51905 122 198 1.01E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS08365 14422b87ac69e7a257d978ca6f9e03d1 658 SUPERFAMILY SSF51905 4 53 1.01E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS08365 14422b87ac69e7a257d978ca6f9e03d1 658 Pfam PF13454 FAD-NAD(P)-binding 10 191 9.6E-45 T 06-07-2017 SMD11_RS08365 14422b87ac69e7a257d978ca6f9e03d1 658 Gene3D G3DSA:3.50.50.60 7 198 1.5E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS08365 14422b87ac69e7a257d978ca6f9e03d1 658 Gene3D G3DSA:3.50.50.60 571 608 1.5E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS20705 889dca682eaf256b8bb4ed24b8c79e6e 164 Pfam PF06262 Zinicin-like metallopeptidase 92 159 1.8E-9 T 06-07-2017 IPR010428 Zinicin-like metallopeptidase SMD11_RS20705 889dca682eaf256b8bb4ed24b8c79e6e 164 SUPERFAMILY SSF55486 39 161 1.9E-21 T 06-07-2017 SMD11_RS06655 34e27e9d0f400292da76eb0aae78b8f9 345 Gene3D G3DSA:2.70.170.10 107 204 7.9E-7 T 06-07-2017 IPR006202 Neurotransmitter-gated ion-channel ligand-binding domain GO:0005230|GO:0006810|GO:0016020 SMD11_RS10500 0a3b8d4103cadb977a006d976bb0ca51 169 Gene3D G3DSA:2.80.10.50 42 167 7.8E-20 T 06-07-2017 SMD11_RS10500 0a3b8d4103cadb977a006d976bb0ca51 169 Pfam PF00652 Ricin-type beta-trefoil lectin domain 44 166 2.5E-17 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS10500 0a3b8d4103cadb977a006d976bb0ca51 169 SUPERFAMILY SSF50370 41 167 4.11E-22 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS10500 0a3b8d4103cadb977a006d976bb0ca51 169 SMART SM00458 42 169 1.7E-8 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS21715 5ee8096c76f2de3c5c0c99fcb16bc701 302 Pfam PF14472 Domain of unknown function (DUF4429) 140 225 8.0E-22 T 06-07-2017 IPR027860 Domain of unknown function DUF4429 SMD11_RS21715 5ee8096c76f2de3c5c0c99fcb16bc701 302 Pfam PF14472 Domain of unknown function (DUF4429) 11 105 4.2E-18 T 06-07-2017 IPR027860 Domain of unknown function DUF4429 SMD11_RS21715 5ee8096c76f2de3c5c0c99fcb16bc701 302 Pfam PF09851 Short C-terminal domain 273 299 1.7E-6 T 06-07-2017 IPR018649 SHOCT domain SMD11_RS21170 16262d2d647eaaa482537e37c8903b17 495 Pfam PF10708 Protein of unknown function (DUF2510) 16 46 8.6E-9 T 06-07-2017 IPR018929 Domain of unknown function DUF2510 SMD11_RS21170 16262d2d647eaaa482537e37c8903b17 495 Pfam PF06271 RDD family 336 486 1.8E-21 T 06-07-2017 IPR010432 RDD SMD11_RS17635 015bb8d3b0f40033a337e32844b213a1 61 Pfam PF04149 Domain of unknown function (DUF397) 6 57 2.9E-11 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS22245 879beb11daee2ea1fad909a29b5137dd 537 Gene3D G3DSA:1.10.510.10 92 272 1.6E-47 T 06-07-2017 SMD11_RS22245 879beb11daee2ea1fad909a29b5137dd 537 Pfam PF00069 Protein kinase domain 23 271 1.1E-48 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS22245 879beb11daee2ea1fad909a29b5137dd 537 Gene3D G3DSA:3.30.200.20 15 91 9.7E-24 T 06-07-2017 SMD11_RS22245 879beb11daee2ea1fad909a29b5137dd 537 SUPERFAMILY SSF56112 16 301 6.92E-72 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS22245 879beb11daee2ea1fad909a29b5137dd 537 SMART SM00220 23 279 3.1E-64 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS22245 879beb11daee2ea1fad909a29b5137dd 537 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 29 52 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS22245 879beb11daee2ea1fad909a29b5137dd 537 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 145 157 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS04530 34acc16617637d59952bc872b25ced45 67 Gene3D G3DSA:3.90.820.10 14 64 9.7E-24 T 06-07-2017 SMD11_RS04530 34acc16617637d59952bc872b25ced45 67 SUPERFAMILY SSF160582 7 64 2.22E-21 T 06-07-2017 SMD11_RS04530 34acc16617637d59952bc872b25ced45 67 SMART SM00923 7 56 2.4E-22 T 06-07-2017 IPR005153 MbtH-like protein SMD11_RS04530 34acc16617637d59952bc872b25ced45 67 Pfam PF03621 MbtH-like protein 7 56 1.9E-22 T 06-07-2017 IPR005153 MbtH-like protein SMD11_RS16030 e2bcac9d02ebd38f184477bac295bd9a 405 Gene3D G3DSA:1.20.1250.20 21 205 8.0E-30 T 06-07-2017 SMD11_RS16030 e2bcac9d02ebd38f184477bac295bd9a 405 SUPERFAMILY SSF103473 15 389 3.01E-54 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS16030 e2bcac9d02ebd38f184477bac295bd9a 405 Gene3D G3DSA:1.20.1250.20 218 388 1.3E-15 T 06-07-2017 SMD11_RS16030 e2bcac9d02ebd38f184477bac295bd9a 405 Pfam PF07690 Major Facilitator Superfamily 28 245 9.2E-26 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS20630 d46b7ccd73bbb299be057d6236fe2962 337 SUPERFAMILY SSF53448 5 248 2.25E-44 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20630 d46b7ccd73bbb299be057d6236fe2962 337 Gene3D G3DSA:3.90.550.10 7 240 1.5E-37 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20630 d46b7ccd73bbb299be057d6236fe2962 337 Pfam PF00535 Glycosyl transferase family 2 10 173 1.0E-21 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD11_RS14090 26ee8938390de3e15040839bdd470eb0 722 SUPERFAMILY SSF82866 110 346 2.09E-31 T 06-07-2017 SMD11_RS14090 26ee8938390de3e15040839bdd470eb0 722 SUPERFAMILY SSF82866 489 695 5.62E-35 T 06-07-2017 SMD11_RS14090 26ee8938390de3e15040839bdd470eb0 722 Gene3D G3DSA:1.20.1640.10 140 350 1.6E-32 T 06-07-2017 SMD11_RS14090 26ee8938390de3e15040839bdd470eb0 722 Gene3D G3DSA:1.20.1640.10 500 698 2.5E-32 T 06-07-2017 SMD11_RS14090 26ee8938390de3e15040839bdd470eb0 722 Pfam PF03176 MMPL family 43 371 1.2E-61 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 SMD11_RS14090 26ee8938390de3e15040839bdd470eb0 722 Pfam PF03176 MMPL family 402 695 8.7E-53 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 SMD11_RS11840 692d953ab0c85f2fabd0850f24956d60 79 Pfam PF11314 Protein of unknown function (DUF3117) 28 77 1.1E-28 T 06-07-2017 IPR021465 Protein of unknown function DUF3117 SMD11_RS08630 a58138e1a05bdf5d152736a05b0503b9 268 Gene3D G3DSA:2.70.70.10 110 262 9.6E-44 T 06-07-2017 SMD11_RS08630 a58138e1a05bdf5d152736a05b0503b9 268 Pfam PF01551 Peptidase family M23 160 257 2.7E-30 T 06-07-2017 IPR016047 Peptidase M23 SMD11_RS08630 a58138e1a05bdf5d152736a05b0503b9 268 SUPERFAMILY SSF51261 88 261 1.31E-44 T 06-07-2017 IPR011055 Duplicated hybrid motif SMD11_RS04090 fb02eb03336e0c3715c423a9af10ae47 113 Pfam PF09360 Iron-binding zinc finger CDGSH type 64 108 2.7E-14 T 06-07-2017 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 SMD11_RS04090 fb02eb03336e0c3715c423a9af10ae47 113 SMART SM00704 69 113 2.7E-11 T 06-07-2017 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 SMD11_RS28920 dba96c82acc3c10c814121597af2e5dd 250 SMART SM00824 Thioesterase 26 244 0.0047 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD11_RS28920 dba96c82acc3c10c814121597af2e5dd 250 Gene3D G3DSA:3.40.50.1820 16 248 4.0E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28920 dba96c82acc3c10c814121597af2e5dd 250 SUPERFAMILY SSF53474 4 248 3.27E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28920 dba96c82acc3c10c814121597af2e5dd 250 Pfam PF00975 Thioesterase domain 24 244 4.8E-53 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS20150 51586028eb98346b71777ba222618f0b 320 PRINTS PR00075 Fatty acid desaturase family 1 signature 78 98 3.5E-16 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD11_RS20150 51586028eb98346b71777ba222618f0b 320 PRINTS PR00075 Fatty acid desaturase family 1 signature 55 77 3.5E-16 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD11_RS20150 51586028eb98346b71777ba222618f0b 320 PRINTS PR00075 Fatty acid desaturase family 1 signature 215 236 3.5E-16 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD11_RS20150 51586028eb98346b71777ba222618f0b 320 PRINTS PR00075 Fatty acid desaturase family 1 signature 258 272 3.5E-16 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD11_RS20150 51586028eb98346b71777ba222618f0b 320 Pfam PF00487 Fatty acid desaturase 56 275 6.5E-21 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 SMD11_RS01800 3ed79685906c6260449f89a4f14829df 186 SUPERFAMILY SSF55729 8 175 1.24E-38 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS01800 3ed79685906c6260449f89a4f14829df 186 Pfam PF13302 Acetyltransferase (GNAT) domain 13 151 3.9E-19 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS01800 3ed79685906c6260449f89a4f14829df 186 Gene3D G3DSA:3.40.630.30 9 176 9.3E-42 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS03680 ab104b3b7ec0451d31cdab74639a87b4 397 Pfam PF09992 Phosphodiester glycosidase 236 394 1.2E-24 T 06-07-2017 IPR018711 Phosphodiester glycosidase SMD11_RS29590 71b319f698c5aff6b822e5cdcf0d586d 193 SUPERFAMILY SSF54427 15 172 2.3E-24 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS29590 71b319f698c5aff6b822e5cdcf0d586d 193 Pfam PF13577 SnoaL-like domain 25 160 3.0E-21 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain SMD11_RS29590 71b319f698c5aff6b822e5cdcf0d586d 193 Gene3D G3DSA:3.10.450.50 25 171 4.6E-26 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS04115 8ecc3d429e183c0dfd085c03cdcb55ed 411 SUPERFAMILY SSF48576 95 183 5.76E-41 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS04115 8ecc3d429e183c0dfd085c03cdcb55ed 411 SUPERFAMILY SSF48576 215 410 5.76E-41 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS04115 8ecc3d429e183c0dfd085c03cdcb55ed 411 Pfam PF03936 Terpene synthase family, metal binding domain 240 361 6.3E-8 T 06-07-2017 IPR005630 Terpene synthase, metal-binding domain GO:0000287|GO:0010333|GO:0016829 SMD11_RS04115 8ecc3d429e183c0dfd085c03cdcb55ed 411 Gene3D G3DSA:1.10.600.10 94 410 3.7E-59 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS31245 d9226a9d6af6142e72adc5dde0ec3dbf 321 Gene3D G3DSA:1.10.3470.10 1 318 5.8E-84 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS31245 d9226a9d6af6142e72adc5dde0ec3dbf 321 Pfam PF01032 FecCD transport family 8 313 4.0E-77 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD11_RS31245 d9226a9d6af6142e72adc5dde0ec3dbf 321 SUPERFAMILY SSF81345 2 312 3.4E-65 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS32950 dca2962c470591c9cc5f7cb613f66c18 116 Gene3D G3DSA:3.10.180.10 8 112 4.8E-6 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS32950 dca2962c470591c9cc5f7cb613f66c18 116 SUPERFAMILY SSF54593 5 113 1.07E-9 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS06920 6074862a710017237128dcdefd2dd769 209 Gene3D G3DSA:3.90.550.10 17 207 7.4E-35 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS06920 6074862a710017237128dcdefd2dd769 209 Pfam PF12804 MobA-like NTP transferase domain 20 181 5.2E-37 T 06-07-2017 IPR025877 MobA-like NTP transferase SMD11_RS06920 6074862a710017237128dcdefd2dd769 209 SUPERFAMILY SSF53448 18 205 7.21E-33 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS02205 867fd04d4579b2c5107cdbbbaf9ed499 2042 Pfam PF13699 Domain of unknown function (DUF4157) 47 121 7.4E-27 T 06-07-2017 IPR025295 Domain of unknown function DUF4157 SMD11_RS32010 322d700b12dfae019c6a333f5194c23e 219 Gene3D G3DSA:3.40.50.360 9 190 2.9E-45 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS32010 322d700b12dfae019c6a333f5194c23e 219 SUPERFAMILY SSF52218 11 184 1.96E-41 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS32010 322d700b12dfae019c6a333f5194c23e 219 Pfam PF03358 NADPH-dependent FMN reductase 10 159 1.3E-30 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMD11_RS26125 23f97bb6c0697e4ba2eb5259e029ca67 266 Pfam PF01522 Polysaccharide deacetylase 61 193 2.1E-34 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS26125 23f97bb6c0697e4ba2eb5259e029ca67 266 Gene3D G3DSA:3.20.20.370 36 193 2.1E-33 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS26125 23f97bb6c0697e4ba2eb5259e029ca67 266 SUPERFAMILY SSF88713 23 195 2.72E-43 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS23195 d10e7add0f892dd374362241449425a3 348 Gene3D G3DSA:3.40.47.10 219 345 1.2E-45 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS23195 d10e7add0f892dd374362241449425a3 348 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 257 346 3.3E-29 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS23195 d10e7add0f892dd374362241449425a3 348 Gene3D G3DSA:3.40.47.10 14 181 1.1E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS23195 d10e7add0f892dd374362241449425a3 348 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 13 346 8.0E-106 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS23195 d10e7add0f892dd374362241449425a3 348 SUPERFAMILY SSF53901 11 346 2.31E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS23195 d10e7add0f892dd374362241449425a3 348 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 12 347 59.848 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS23195 d10e7add0f892dd374362241449425a3 348 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 117 194 1.1E-24 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS25915 7a1113d733f0ee30583a48bb9085b5cd 121 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 25 39 - T 06-07-2017 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 SMD11_RS25915 7a1113d733f0ee30583a48bb9085b5cd 121 Pfam PF00741 Gas vesicle protein 24 61 1.4E-15 T 06-07-2017 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMD11_RS15150 c64c91b87b9e10f82b4e712825efe5dd 141 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 98 1.2E-17 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 SMD11_RS15150 c64c91b87b9e10f82b4e712825efe5dd 141 SUPERFAMILY SSF53927 1 136 1.44E-28 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 SMD11_RS15150 c64c91b87b9e10f82b4e712825efe5dd 141 Gene3D G3DSA:3.40.140.10 1 135 1.2E-21 T 06-07-2017 SMD11_RS10255 e3c6c716e720e1e248d18e37402167f0 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 132 330 4.6E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS10255 e3c6c716e720e1e248d18e37402167f0 332 Gene3D G3DSA:1.10.3720.10 106 327 3.2E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS10255 e3c6c716e720e1e248d18e37402167f0 332 SUPERFAMILY SSF161098 107 313 3.74E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS14650 eb39e78adecfb0771f07e5dc87695c93 302 SUPERFAMILY SSF52540 14 279 2.02E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12265 dc91aeb9f8fde725586a568a1f531275 398 SUPERFAMILY SSF103473 3 374 4.32E-52 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS12265 dc91aeb9f8fde725586a568a1f531275 398 Pfam PF07690 Major Facilitator Superfamily 9 315 1.1E-35 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS12265 dc91aeb9f8fde725586a568a1f531275 398 Gene3D G3DSA:1.20.1250.20 3 181 5.5E-26 T 06-07-2017 SMD11_RS12265 dc91aeb9f8fde725586a568a1f531275 398 Gene3D G3DSA:1.20.1250.20 193 372 4.1E-16 T 06-07-2017 SMD11_RS10205 9fff0625b5ea9d1f8c6ce494c0456e28 301 Pfam PF13707 RloB-like protein 41 225 8.7E-25 T 06-07-2017 IPR025591 RloB-like protein SMD11_RS30020 2dc51be4abc022ff013f207e17b8560a 159 Gene3D G3DSA:3.90.79.10 21 133 5.5E-26 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS30020 2dc51be4abc022ff013f207e17b8560a 159 Pfam PF00293 NUDIX domain 21 138 5.0E-18 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 SMD11_RS30020 2dc51be4abc022ff013f207e17b8560a 159 PRINTS PR00502 NUDIX hydrolase family signature 44 58 5.6E-8 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS30020 2dc51be4abc022ff013f207e17b8560a 159 PRINTS PR00502 NUDIX hydrolase family signature 58 73 5.6E-8 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SMD11_RS30020 2dc51be4abc022ff013f207e17b8560a 159 SUPERFAMILY SSF55811 18 136 2.71E-25 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 SMD11_RS28405 2b46a23debf680b2bee692a9c698cf55 407 Pfam PF00999 Sodium/hydrogen exchanger family 16 368 1.2E-41 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SMD11_RS05205 a9d9e3d80ce221f1300a49ddda52d329 263 Gene3D G3DSA:3.60.130.10 75 228 6.3E-22 T 06-07-2017 SMD11_RS05205 a9d9e3d80ce221f1300a49ddda52d329 263 SUPERFAMILY SSF51197 17 235 2.52E-27 T 06-07-2017 SMD11_RS05205 a9d9e3d80ce221f1300a49ddda52d329 263 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 12 233 1.9E-20 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 SMD11_RS10910 bcdde546ec1581af59ab44e86de738f8 488 PIRSF PIRSF006060 3 474 3.8E-58 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS10910 bcdde546ec1581af59ab44e86de738f8 488 Pfam PF13520 Amino acid permease 4 442 1.6E-63 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS04895 cb6060edc69ee66fc9cbf6de6d7fbee8 422 SUPERFAMILY SSF103473 15 400 2.35E-28 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS04895 cb6060edc69ee66fc9cbf6de6d7fbee8 422 Gene3D G3DSA:1.20.1250.20 15 158 2.4E-6 T 06-07-2017 SMD11_RS04895 cb6060edc69ee66fc9cbf6de6d7fbee8 422 Gene3D G3DSA:1.20.1250.20 218 402 1.7E-11 T 06-07-2017 SMD11_RS31715 50e3c640ee92c7f78abb38e7304b4e84 497 Pfam PF01494 FAD binding domain 13 354 5.3E-84 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS31715 50e3c640ee92c7f78abb38e7304b4e84 497 Gene3D G3DSA:3.50.50.60 289 327 5.7E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31715 50e3c640ee92c7f78abb38e7304b4e84 497 Gene3D G3DSA:3.50.50.60 12 177 5.7E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31715 50e3c640ee92c7f78abb38e7304b4e84 497 Gene3D G3DSA:3.30.9.10 178 284 1.0E-10 T 06-07-2017 SMD11_RS31715 50e3c640ee92c7f78abb38e7304b4e84 497 Gene3D G3DSA:3.30.9.10 339 364 1.0E-10 T 06-07-2017 SMD11_RS31715 50e3c640ee92c7f78abb38e7304b4e84 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 306 3.9E-46 T 06-07-2017 SMD11_RS31715 50e3c640ee92c7f78abb38e7304b4e84 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 166 181 3.9E-46 T 06-07-2017 SMD11_RS31715 50e3c640ee92c7f78abb38e7304b4e84 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 342 358 3.9E-46 T 06-07-2017 SMD11_RS31715 50e3c640ee92c7f78abb38e7304b4e84 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 322 3.9E-46 T 06-07-2017 SMD11_RS31715 50e3c640ee92c7f78abb38e7304b4e84 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 13 35 3.9E-46 T 06-07-2017 SMD11_RS31715 50e3c640ee92c7f78abb38e7304b4e84 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 324 342 3.9E-46 T 06-07-2017 SMD11_RS31715 50e3c640ee92c7f78abb38e7304b4e84 497 SUPERFAMILY SSF51905 12 187 1.69E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31715 50e3c640ee92c7f78abb38e7304b4e84 497 SUPERFAMILY SSF51905 278 382 1.69E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS24360 1b590375a82b7e0f2ac03b6ffb9eea51 451 Pfam PF01474 Class-II DAHP synthetase family 13 445 3.1E-202 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMD11_RS24360 1b590375a82b7e0f2ac03b6ffb9eea51 451 SUPERFAMILY SSF51569 11 449 3.59E-198 T 06-07-2017 SMD11_RS24360 1b590375a82b7e0f2ac03b6ffb9eea51 451 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 13 451 9.1E-235 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMD11_RS31610 76817330817ddd5780cf445af1e04a75 120 Pfam PF06078 Bacterial protein of unknown function (DUF937) 69 117 5.5E-6 T 06-07-2017 IPR009282 Protein of unknown function DUF937 SMD11_RS31610 76817330817ddd5780cf445af1e04a75 120 Pfam PF06078 Bacterial protein of unknown function (DUF937) 12 81 2.2E-5 T 06-07-2017 IPR009282 Protein of unknown function DUF937 SMD11_RS11340 b743008fd7b5456f4646d85889204dee 95 Pfam PF11755 Protein of unknown function (DUF3311) 29 86 2.5E-20 T 06-07-2017 IPR021741 Protein of unknown function DUF3311 SMD11_RS04480 fcd80e377ccd9f56c89f58b387ef94a3 118 SUPERFAMILY SSF46785 1 92 2.39E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS04480 fcd80e377ccd9f56c89f58b387ef94a3 118 Gene3D G3DSA:1.10.10.10 1 67 6.0E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17625 48fdf3967925c61f25c914dbe6947e3c 230 SUPERFAMILY SSF55874 131 207 4.73E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS17625 48fdf3967925c61f25c914dbe6947e3c 230 Pfam PF13581 Histidine kinase-like ATPase domain 103 202 1.5E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08210 619618809d53971466e04132894cc7ad 263 Pfam PF00975 Thioesterase domain 24 245 7.3E-58 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS08210 619618809d53971466e04132894cc7ad 263 SUPERFAMILY SSF53474 4 246 2.01E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS08210 619618809d53971466e04132894cc7ad 263 SMART SM00824 Thioesterase 26 247 1.2E-4 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 SMD11_RS08210 619618809d53971466e04132894cc7ad 263 Gene3D G3DSA:3.40.50.1820 10 248 6.4E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS08175 569305036b98c95d44069d8253195053 271 SMART SM00530 13 68 3.8E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS08175 569305036b98c95d44069d8253195053 271 Pfam PF01381 Helix-turn-helix 14 67 6.1E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS08175 569305036b98c95d44069d8253195053 271 SUPERFAMILY SSF47413 9 67 6.76E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS08175 569305036b98c95d44069d8253195053 271 Gene3D G3DSA:1.10.260.40 10 67 2.6E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS26000 ec33ddf1d9d936efd64740d6a76436fc 250 PRINTS PR00721 Stomatin signature 200 223 2.6E-60 T 06-07-2017 IPR001972 Stomatin family GO:0016020 SMD11_RS26000 ec33ddf1d9d936efd64740d6a76436fc 250 PRINTS PR00721 Stomatin signature 156 174 2.6E-60 T 06-07-2017 IPR001972 Stomatin family GO:0016020 SMD11_RS26000 ec33ddf1d9d936efd64740d6a76436fc 250 PRINTS PR00721 Stomatin signature 29 51 2.6E-60 T 06-07-2017 IPR001972 Stomatin family GO:0016020 SMD11_RS26000 ec33ddf1d9d936efd64740d6a76436fc 250 PRINTS PR00721 Stomatin signature 77 98 2.6E-60 T 06-07-2017 IPR001972 Stomatin family GO:0016020 SMD11_RS26000 ec33ddf1d9d936efd64740d6a76436fc 250 PRINTS PR00721 Stomatin signature 132 155 2.6E-60 T 06-07-2017 IPR001972 Stomatin family GO:0016020 SMD11_RS26000 ec33ddf1d9d936efd64740d6a76436fc 250 PRINTS PR00721 Stomatin signature 112 129 2.6E-60 T 06-07-2017 IPR001972 Stomatin family GO:0016020 SMD11_RS26000 ec33ddf1d9d936efd64740d6a76436fc 250 PRINTS PR00721 Stomatin signature 175 196 2.6E-60 T 06-07-2017 IPR001972 Stomatin family GO:0016020 SMD11_RS26000 ec33ddf1d9d936efd64740d6a76436fc 250 SUPERFAMILY SSF117892 54 187 3.27E-41 T 06-07-2017 IPR001107 Band 7 domain SMD11_RS26000 ec33ddf1d9d936efd64740d6a76436fc 250 Pfam PF01145 SPFH domain / Band 7 family 26 196 2.2E-34 T 06-07-2017 IPR001107 Band 7 domain SMD11_RS26000 ec33ddf1d9d936efd64740d6a76436fc 250 SMART SM00244 22 180 4.2E-60 T 06-07-2017 IPR001107 Band 7 domain SMD11_RS02965 a3ee84db9055c2e182734023d055ebf3 167 SUPERFAMILY SSF88723 1 130 7.85E-5 T 06-07-2017 IPR029060 PIN domain-like SMD11_RS21780 c9b034e8cfc33fd29ac09a293e35328f 347 Gene3D G3DSA:2.130.10.10 50 258 6.3E-7 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS21780 c9b034e8cfc33fd29ac09a293e35328f 347 SUPERFAMILY SSF63829 305 334 2.42E-10 T 06-07-2017 SMD11_RS21780 c9b034e8cfc33fd29ac09a293e35328f 347 SUPERFAMILY SSF63829 49 256 2.42E-10 T 06-07-2017 SMD11_RS21780 c9b034e8cfc33fd29ac09a293e35328f 347 Pfam PF13449 Esterase-like activity of phytase 57 330 2.3E-61 T 06-07-2017 IPR027372 Phytase-like domain SMD11_RS31380 e01fcee8f7edb867f093c7e2bf2bb32c 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SMD11_RS31380 e01fcee8f7edb867f093c7e2bf2bb32c 257 SUPERFAMILY SSF52096 1 256 5.83E-90 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS31380 e01fcee8f7edb867f093c7e2bf2bb32c 257 Gene3D G3DSA:3.90.226.10 1 197 1.3E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS31380 e01fcee8f7edb867f093c7e2bf2bb32c 257 Gene3D G3DSA:1.10.12.10 204 257 6.5E-23 T 06-07-2017 IPR014748 Crontonase, C-terminal SMD11_RS31380 e01fcee8f7edb867f093c7e2bf2bb32c 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 256 6.3E-79 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS14400 c7a02570d569c874192d7166f49e11a8 236 Pfam PF11209 Protein of unknown function (DUF2993) 20 227 9.8E-38 T 06-07-2017 IPR021373 Protein of unknown function DUF2993 SMD11_RS17050 89364c351b80cdecb8124a9b54df71ea 508 SMART SM00331 11 237 5.4E-39 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS17050 89364c351b80cdecb8124a9b54df71ea 508 SUPERFAMILY SSF81606 4 236 3.79E-66 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS17050 89364c351b80cdecb8124a9b54df71ea 508 Gene3D G3DSA:3.60.40.10 2 237 1.8E-73 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS17050 89364c351b80cdecb8124a9b54df71ea 508 SMART SM00332 2 235 3.1E-28 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS17050 89364c351b80cdecb8124a9b54df71ea 508 Pfam PF00481 Protein phosphatase 2C 22 229 1.4E-10 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS06135 7b982ea8fba37c9a8120a5e057daffd3 484 Pfam PF13148 Protein of unknown function (DUF3987) 121 325 1.2E-12 T 06-07-2017 IPR025048 Protein of unknown function DUF3987) SMD11_RS03225 c663ca8458502e685bde8cfa7447ac42 168 Gene3D G3DSA:2.30.110.10 14 163 5.4E-53 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS03225 c663ca8458502e685bde8cfa7447ac42 168 Pfam PF01613 Flavin reductase like domain 22 166 8.4E-39 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS03225 c663ca8458502e685bde8cfa7447ac42 168 SMART SM00903 22 165 8.0E-51 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS03225 c663ca8458502e685bde8cfa7447ac42 168 SUPERFAMILY SSF50475 15 164 4.22E-42 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS11755 33838c7c5653252a4cbbb8dcdbe038b2 287 SMART SM00481 3 67 3.4E-12 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 SMD11_RS11755 33838c7c5653252a4cbbb8dcdbe038b2 287 SUPERFAMILY SSF89550 166 259 2.35E-41 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMD11_RS11755 33838c7c5653252a4cbbb8dcdbe038b2 287 SUPERFAMILY SSF89550 2 83 2.35E-41 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SMD11_RS11755 33838c7c5653252a4cbbb8dcdbe038b2 287 Gene3D G3DSA:3.20.20.140 2 88 9.2E-33 T 06-07-2017 SMD11_RS11755 33838c7c5653252a4cbbb8dcdbe038b2 287 Gene3D G3DSA:3.20.20.140 153 257 9.2E-33 T 06-07-2017 SMD11_RS11755 33838c7c5653252a4cbbb8dcdbe038b2 287 Pfam PF02811 PHP domain 4 80 9.5E-9 T 06-07-2017 IPR004013 PHP domain GO:0003824 SMD11_RS16310 234947fb23a0746100f1402ef9e87b4e 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 251 1.2E-48 T 06-07-2017 SMD11_RS16310 234947fb23a0746100f1402ef9e87b4e 253 SUPERFAMILY SSF51735 9 252 4.57E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS16310 234947fb23a0746100f1402ef9e87b4e 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.7E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16310 234947fb23a0746100f1402ef9e87b4e 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.7E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16310 234947fb23a0746100f1402ef9e87b4e 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 1.7E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16310 234947fb23a0746100f1402ef9e87b4e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 8.1E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16310 234947fb23a0746100f1402ef9e87b4e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 8.1E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16310 234947fb23a0746100f1402ef9e87b4e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 8.1E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16310 234947fb23a0746100f1402ef9e87b4e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 8.1E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16310 234947fb23a0746100f1402ef9e87b4e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 8.1E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS16310 234947fb23a0746100f1402ef9e87b4e 253 Gene3D G3DSA:3.40.50.720 7 252 1.0E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS09075 46ba9a1833cd9126a9e43c67e1a66c5c 246 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 19 238 4.3E-62 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD11_RS09075 46ba9a1833cd9126a9e43c67e1a66c5c 246 Hamap MF_01408 Thymidylate synthase ThyX [thyX]. 15 246 27.756 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD11_RS09075 46ba9a1833cd9126a9e43c67e1a66c5c 246 Pfam PF02511 Thymidylate synthase complementing protein 20 232 2.6E-50 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD11_RS09075 46ba9a1833cd9126a9e43c67e1a66c5c 246 SUPERFAMILY SSF69796 13 239 6.8E-52 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 SMD11_RS24535 09e7f41215874db2e87d7b71acbb22c5 248 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 22 246 1.5E-69 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase SMD11_RS24535 09e7f41215874db2e87d7b71acbb22c5 248 Gene3D G3DSA:3.60.140.10 11 247 2.0E-82 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase SMD11_RS24535 09e7f41215874db2e87d7b71acbb22c5 248 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 27 247 6.1E-50 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase SMD11_RS24535 09e7f41215874db2e87d7b71acbb22c5 248 SUPERFAMILY SSF64438 13 248 1.74E-74 T 06-07-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic SMD11_RS15880 fe0a298986f98fd42f9d785126d68ab6 610 SUPERFAMILY SSF53067 129 214 7.12E-19 T 06-07-2017 SMD11_RS15880 fe0a298986f98fd42f9d785126d68ab6 610 SUPERFAMILY SSF53067 4 81 7.12E-19 T 06-07-2017 SMD11_RS15880 fe0a298986f98fd42f9d785126d68ab6 610 SUPERFAMILY SSF53067 252 348 7.12E-19 T 06-07-2017 SMD11_RS15880 fe0a298986f98fd42f9d785126d68ab6 610 Pfam PF16861 Carbamoyltransferase C-terminus 404 591 2.7E-75 T 06-07-2017 IPR031730 Carbamoyltransferase, C-terminal SMD11_RS15880 fe0a298986f98fd42f9d785126d68ab6 610 Pfam PF02543 Carbamoyltransferase N-terminus 5 346 2.1E-85 T 06-07-2017 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 SMD11_RS01775 a3580d22578f397934f2d01dfff5d4fe 365 Gene3D G3DSA:3.30.70.100 242 328 2.4E-15 T 06-07-2017 SMD11_RS01775 a3580d22578f397934f2d01dfff5d4fe 365 Gene3D G3DSA:2.30.30.60 185 234 3.5E-13 T 06-07-2017 SMD11_RS01775 a3580d22578f397934f2d01dfff5d4fe 365 SUPERFAMILY SSF82861 85 167 1.28E-11 T 06-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 SMD11_RS01775 a3580d22578f397934f2d01dfff5d4fe 365 Pfam PF00924 Mechanosensitive ion channel 126 330 2.9E-47 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SMD11_RS01775 a3580d22578f397934f2d01dfff5d4fe 365 SUPERFAMILY SSF82689 242 340 3.14E-18 T 06-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 SMD11_RS01775 a3580d22578f397934f2d01dfff5d4fe 365 SUPERFAMILY SSF50182 168 235 6.21E-14 T 06-07-2017 IPR010920 LSM domain SMD11_RS30570 820d7f1a6a3f2a6dcb6499201a6e5bab 145 SUPERFAMILY SSF52833 70 138 2.87E-8 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS30570 820d7f1a6a3f2a6dcb6499201a6e5bab 145 Pfam PF00462 Glutaredoxin 70 127 5.2E-6 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 SMD11_RS30570 820d7f1a6a3f2a6dcb6499201a6e5bab 145 Gene3D G3DSA:3.40.30.10 70 135 4.3E-7 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS05330 5033df90ec694f4a6def02e23fcced9d 379 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 124 138 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 SMD11_RS05330 5033df90ec694f4a6def02e23fcced9d 379 Gene3D G3DSA:1.10.600.10 85 378 3.9E-83 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS05330 5033df90ec694f4a6def02e23fcced9d 379 Pfam PF00348 Polyprenyl synthetase 85 308 1.3E-52 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 SMD11_RS05330 5033df90ec694f4a6def02e23fcced9d 379 SUPERFAMILY SSF48576 55 378 4.19E-76 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS29190 f72823e21e38aaa086be52c421e39661 332 Gene3D G3DSA:3.40.50.720 1 239 3.9E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29190 f72823e21e38aaa086be52c421e39661 332 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 203 1.2E-7 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 SMD11_RS29190 f72823e21e38aaa086be52c421e39661 332 SUPERFAMILY SSF51735 1 261 6.72E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS12990 efc6f55e6344a201cef437a5a7eae873 296 Gene3D G3DSA:3.10.180.10 51 154 2.8E-5 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS12990 efc6f55e6344a201cef437a5a7eae873 296 SUPERFAMILY SSF54593 50 207 1.64E-10 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS21910 c84f9c744ca0aa15e3af6bde32f1929f 508 PIRSF PIRSF026631 12 495 4.9E-72 T 06-07-2017 IPR014529 Uncharacterised conserved protein UCP026631 SMD11_RS21910 c84f9c744ca0aa15e3af6bde32f1929f 508 Pfam PF03703 Bacterial PH domain 240 320 7.5E-6 T 06-07-2017 IPR005182 Domain of unknown function DUF304 SMD11_RS21910 c84f9c744ca0aa15e3af6bde32f1929f 508 Pfam PF03703 Bacterial PH domain 64 141 5.5E-16 T 06-07-2017 IPR005182 Domain of unknown function DUF304 SMD11_RS21910 c84f9c744ca0aa15e3af6bde32f1929f 508 Pfam PF03703 Bacterial PH domain 415 490 2.8E-8 T 06-07-2017 IPR005182 Domain of unknown function DUF304 SMD11_RS05275 23aec715440aedeecb7dec676b33bcf6 85 Pfam PF04149 Domain of unknown function (DUF397) 18 69 7.7E-13 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS19060 2bea1c032892cb298db2ad60ad1f5fe9 539 Pfam PF00005 ABC transporter 21 191 1.4E-19 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS19060 2bea1c032892cb298db2ad60ad1f5fe9 539 Pfam PF00005 ABC transporter 348 475 3.1E-13 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS19060 2bea1c032892cb298db2ad60ad1f5fe9 539 SMART SM00382 29 236 1.4E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS19060 2bea1c032892cb298db2ad60ad1f5fe9 539 SMART SM00382 356 528 1.3E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS19060 2bea1c032892cb298db2ad60ad1f5fe9 539 Gene3D G3DSA:3.40.50.300 136 281 5.1E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19060 2bea1c032892cb298db2ad60ad1f5fe9 539 Gene3D G3DSA:3.40.50.300 9 100 5.1E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19060 2bea1c032892cb298db2ad60ad1f5fe9 539 Gene3D G3DSA:3.40.50.300 347 521 5.1E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19060 2bea1c032892cb298db2ad60ad1f5fe9 539 SUPERFAMILY SSF52540 16 235 9.61E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19060 2bea1c032892cb298db2ad60ad1f5fe9 539 SUPERFAMILY SSF52540 347 522 2.83E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS18725 4bb6df8f43e8855869ce4a9b6ad0c259 526 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 11 522 4.5E-165 T 06-07-2017 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18725 4bb6df8f43e8855869ce4a9b6ad0c259 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 404 430 4.8E-40 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18725 4bb6df8f43e8855869ce4a9b6ad0c259 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 347 366 4.8E-40 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18725 4bb6df8f43e8855869ce4a9b6ad0c259 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 151 170 4.8E-40 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18725 4bb6df8f43e8855869ce4a9b6ad0c259 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 181 205 4.8E-40 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18725 4bb6df8f43e8855869ce4a9b6ad0c259 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 253 277 4.8E-40 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18725 4bb6df8f43e8855869ce4a9b6ad0c259 526 Pfam PF00361 Proton-conducting membrane transporter 147 431 2.9E-60 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS06290 7ee56e9fc829097029355c91d86f9d61 195 Gene3D G3DSA:1.20.120.450 10 58 1.7E-6 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase SMD11_RS06290 7ee56e9fc829097029355c91d86f9d61 195 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 18 136 3.1E-15 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD11_RS06290 7ee56e9fc829097029355c91d86f9d61 195 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 17 178 8.1E-24 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD11_RS06290 7ee56e9fc829097029355c91d86f9d61 195 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 16 193 2.2E-49 T 06-07-2017 IPR017520 Conserved hypothetical protein CHP03086 SMD11_RS06290 7ee56e9fc829097029355c91d86f9d61 195 SUPERFAMILY SSF109854 6 142 3.66E-24 T 06-07-2017 SMD11_RS03780 fd51c5828a15664aad19203343808b15 291 Pfam PF12730 ABC-2 family transporter protein 34 165 1.7E-9 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 SMD11_RS07025 7146c6e6fd245abf9c4271d8b4ab05c2 383 SUPERFAMILY SSF144083 318 380 7.45E-18 T 06-07-2017 SMD11_RS07025 7146c6e6fd245abf9c4271d8b4ab05c2 383 SUPERFAMILY SSF143865 30 300 8.11E-68 T 06-07-2017 SMD11_RS07025 7146c6e6fd245abf9c4271d8b4ab05c2 383 Gene3D G3DSA:1.20.58.340 180 290 2.0E-36 T 06-07-2017 SMD11_RS07025 7146c6e6fd245abf9c4271d8b4ab05c2 383 Gene3D G3DSA:3.30.460.20 26 179 1.7E-43 T 06-07-2017 SMD11_RS07025 7146c6e6fd245abf9c4271d8b4ab05c2 383 Gene3D G3DSA:1.20.58.340 313 383 1.7E-22 T 06-07-2017 SMD11_RS07025 7146c6e6fd245abf9c4271d8b4ab05c2 383 Pfam PF01544 CorA-like Mg2+ transporter protein 77 379 1.5E-62 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SMD11_RS13830 0f97f5405851a951647c8af6ea6d5a11 344 Pfam PF01032 FecCD transport family 29 338 3.0E-88 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD11_RS13830 0f97f5405851a951647c8af6ea6d5a11 344 SUPERFAMILY SSF81345 14 339 1.83E-76 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS13830 0f97f5405851a951647c8af6ea6d5a11 344 Gene3D G3DSA:1.10.3470.10 16 340 2.4E-98 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS19860 082e388818b29014630eb188f60f706e 168 Gene3D G3DSA:3.30.70.640 8 160 2.7E-64 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 SMD11_RS19860 082e388818b29014630eb188f60f706e 168 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 9 155 4.1E-62 T 06-07-2017 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 SMD11_RS19860 082e388818b29014630eb188f60f706e 168 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 7 161 35.812 T 06-07-2017 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type Reactome: R-HSA-947581 SMD11_RS19860 082e388818b29014630eb188f60f706e 168 Pfam PF01967 MoaC family 20 153 7.8E-52 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 SMD11_RS19860 082e388818b29014630eb188f60f706e 168 SUPERFAMILY SSF55040 16 158 2.88E-56 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 SMD11_RS33640 4fbe4dfc4ee582364cfd3635d35942c0 541 SUPERFAMILY SSF51905 503 528 5.98E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS33640 4fbe4dfc4ee582364cfd3635d35942c0 541 SUPERFAMILY SSF51905 30 341 5.98E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS33640 4fbe4dfc4ee582364cfd3635d35942c0 541 Gene3D G3DSA:3.50.50.60 30 97 2.5E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS33640 4fbe4dfc4ee582364cfd3635d35942c0 541 Gene3D G3DSA:3.50.50.60 232 327 2.5E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS33640 4fbe4dfc4ee582364cfd3635d35942c0 541 Pfam PF01593 Flavin containing amine oxidoreductase 42 319 4.4E-15 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 SMD11_RS23500 163a4e3cc189f6a7862a746b1027eb4e 77 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 9 62 4.0E-10 T 06-07-2017 SMD11_RS23500 163a4e3cc189f6a7862a746b1027eb4e 77 Gene3D G3DSA:3.30.70.20 5 69 2.3E-12 T 06-07-2017 SMD11_RS23500 163a4e3cc189f6a7862a746b1027eb4e 77 PRINTS PR00352 3Fe-4S ferredoxin signature 49 61 1.2E-7 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD11_RS23500 163a4e3cc189f6a7862a746b1027eb4e 77 PRINTS PR00352 3Fe-4S ferredoxin signature 9 20 1.2E-7 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD11_RS23500 163a4e3cc189f6a7862a746b1027eb4e 77 PRINTS PR00352 3Fe-4S ferredoxin signature 20 30 1.2E-7 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD11_RS23500 163a4e3cc189f6a7862a746b1027eb4e 77 SUPERFAMILY SSF54862 5 62 1.38E-9 T 06-07-2017 SMD11_RS31415 eb8993a1e225cd40f2db0be877fe1cd8 457 Gene3D G3DSA:1.20.1250.20 13 207 1.6E-17 T 06-07-2017 SMD11_RS31415 eb8993a1e225cd40f2db0be877fe1cd8 457 Gene3D G3DSA:1.20.1250.20 234 445 5.7E-18 T 06-07-2017 SMD11_RS31415 eb8993a1e225cd40f2db0be877fe1cd8 457 Pfam PF07690 Major Facilitator Superfamily 28 388 3.0E-31 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS31415 eb8993a1e225cd40f2db0be877fe1cd8 457 SUPERFAMILY SSF103473 10 444 7.98E-47 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS12655 b2680c8aab6651e02dcc480e44d21987 145 Pfam PF13772 AIG2-like family 59 140 7.1E-21 T 06-07-2017 SMD11_RS12655 b2680c8aab6651e02dcc480e44d21987 145 SUPERFAMILY SSF110857 1 119 1.23E-13 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like SMD11_RS12655 b2680c8aab6651e02dcc480e44d21987 145 Gene3D G3DSA:3.10.490.10 1 145 4.5E-46 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like SMD11_RS05510 04b5a4921fc0f7d5d9a85e24107d2cf7 234 Hamap MF_00801 Endonuclease V [nfi]. 19 234 33.653 T 06-07-2017 IPR007581 Endonuclease V GO:0004519|GO:0006281 SMD11_RS05510 04b5a4921fc0f7d5d9a85e24107d2cf7 234 Pfam PF04493 Endonuclease V 43 224 7.0E-65 T 06-07-2017 IPR007581 Endonuclease V GO:0004519|GO:0006281 SMD11_RS25675 8f031de7243d7ddef927c7545a787a20 92 Gene3D G3DSA:3.10.450.30 2 90 3.4E-40 T 06-07-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 SMD11_RS25675 8f031de7243d7ddef927c7545a787a20 92 SUPERFAMILY SSF53933 3 89 4.68E-36 T 06-07-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 SMD11_RS25675 8f031de7243d7ddef927c7545a787a20 92 Pfam PF00545 ribonuclease 9 87 9.4E-30 T 06-07-2017 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 SMD11_RS26120 bd96b6a7b428ca0d899b0e3101648193 1293 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 356 437 2.6E-7 T 06-07-2017 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain SMD11_RS34160 c4f50e85393385670f9e9d8c671a2568 508 SUPERFAMILY SSF103473 25 226 1.48E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS34160 c4f50e85393385670f9e9d8c671a2568 508 SUPERFAMILY SSF103473 278 495 1.48E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS34160 c4f50e85393385670f9e9d8c671a2568 508 Pfam PF07690 Major Facilitator Superfamily 46 440 1.2E-46 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS34160 c4f50e85393385670f9e9d8c671a2568 508 Gene3D G3DSA:1.20.1250.20 291 494 1.8E-19 T 06-07-2017 SMD11_RS34160 c4f50e85393385670f9e9d8c671a2568 508 Gene3D G3DSA:1.20.1250.20 38 228 1.7E-28 T 06-07-2017 SMD11_RS34160 c4f50e85393385670f9e9d8c671a2568 508 ProSitePatterns PS00216 Sugar transport proteins signature 1. 96 112 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SMD11_RS16970 caec379a7bb2280bb9ae74e91aafdb6b 181 SUPERFAMILY SSF47413 22 74 9.6E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS16970 caec379a7bb2280bb9ae74e91aafdb6b 181 Gene3D G3DSA:1.10.260.40 25 62 2.4E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS05070 a19984b6684078773c0ea7e650932f0c 133 Pfam PF00027 Cyclic nucleotide-binding domain 7 94 1.4E-11 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain SMD11_RS05070 a19984b6684078773c0ea7e650932f0c 133 SUPERFAMILY SSF51206 2 123 1.83E-19 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like SMD11_RS05070 a19984b6684078773c0ea7e650932f0c 133 Gene3D G3DSA:2.60.120.10 4 123 2.9E-14 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS04375 c669dc1ccc7d66f2361deffabaf9de8a 490 Pfam PF00106 short chain dehydrogenase 152 242 2.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS04375 c669dc1ccc7d66f2361deffabaf9de8a 490 Gene3D G3DSA:3.40.50.720 136 238 2.0E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04375 c669dc1ccc7d66f2361deffabaf9de8a 490 Gene3D G3DSA:3.40.50.720 333 466 2.0E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04375 c669dc1ccc7d66f2361deffabaf9de8a 490 SUPERFAMILY SSF51735 335 435 1.33E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04375 c669dc1ccc7d66f2361deffabaf9de8a 490 SUPERFAMILY SSF51735 148 246 1.33E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS34470 1fde8dbb9142d1e33dd01c95da95ef43 153 Pfam PF01609 Transposase DDE domain 11 103 3.1E-14 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 SMD11_RS22320 2a0cbf409d697f8ee0af31e67cf07a6f 178 Pfam PF02441 Flavoprotein 8 130 2.3E-10 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD11_RS22320 2a0cbf409d697f8ee0af31e67cf07a6f 178 Gene3D G3DSA:3.40.50.1950 7 147 1.6E-18 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD11_RS22320 2a0cbf409d697f8ee0af31e67cf07a6f 178 SUPERFAMILY SSF52507 6 147 2.62E-23 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SMD11_RS11225 11d4b345c3fee7c11474434f7a404ce8 181 SUPERFAMILY SSF55729 1 158 2.53E-36 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS11225 11d4b345c3fee7c11474434f7a404ce8 181 Pfam PF00583 Acetyltransferase (GNAT) family 66 144 2.9E-16 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS11225 11d4b345c3fee7c11474434f7a404ce8 181 Gene3D G3DSA:3.40.630.30 2 164 4.0E-58 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS31670 c3f74b63021e2b026f052550816a7026 247 SUPERFAMILY SSF56770 10 64 1.83E-10 T 06-07-2017 SMD11_RS31670 c3f74b63021e2b026f052550816a7026 247 Gene3D G3DSA:3.40.50.700 8 118 1.0E-5 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS31670 c3f74b63021e2b026f052550816a7026 247 SUPERFAMILY SSF56770 74 120 2.75E-9 T 06-07-2017 SMD11_RS12790 c916e67cc6f8eb4bac3b3348c2613366 463 Gene3D G3DSA:3.40.50.150 35 192 5.4E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS12790 c916e67cc6f8eb4bac3b3348c2613366 463 SUPERFAMILY SSF53335 33 187 9.33E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS00510 2c364d46d0933b0bdae4d397bf3b8cae 148 Gene3D G3DSA:3.90.190.10 56 141 7.1E-17 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like SMD11_RS00510 2c364d46d0933b0bdae4d397bf3b8cae 148 SUPERFAMILY SSF52799 50 141 2.55E-17 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like SMD11_RS00510 2c364d46d0933b0bdae4d397bf3b8cae 148 Pfam PF00102 Protein-tyrosine phosphatase 50 114 9.6E-5 T 06-07-2017 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 SMD11_RS12005 823f3f3fd8e9e25e08b08146352e9032 540 Gene3D G3DSA:3.40.190.10 205 318 3.6E-29 T 06-07-2017 SMD11_RS12005 823f3f3fd8e9e25e08b08146352e9032 540 Gene3D G3DSA:3.10.105.10 319 511 5.0E-37 T 06-07-2017 SMD11_RS12005 823f3f3fd8e9e25e08b08146352e9032 540 Gene3D G3DSA:3.90.76.10 46 204 2.7E-30 T 06-07-2017 SMD11_RS12005 823f3f3fd8e9e25e08b08146352e9032 540 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 460 4.2E-50 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain SMD11_RS12005 823f3f3fd8e9e25e08b08146352e9032 540 SUPERFAMILY SSF53850 31 534 1.76E-89 T 06-07-2017 SMD11_RS12005 823f3f3fd8e9e25e08b08146352e9032 540 PIRSF PIRSF002741 9 536 1.9E-58 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD11_RS07790 a46f12fc07b8f1f3c5d228e673e7a4c2 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 1.9E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS07790 a46f12fc07b8f1f3c5d228e673e7a4c2 185 Gene3D G3DSA:1.10.357.10 4 163 8.9E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS07790 a46f12fc07b8f1f3c5d228e673e7a4c2 185 SUPERFAMILY SSF46689 3 75 2.1E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS02635 9a6b062adf266272f1af8218964d50cc 1795 Pfam PF10282 Lactonase, 7-bladed beta-propeller 1634 1757 3.3E-7 T 06-07-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 SMD11_RS02635 9a6b062adf266272f1af8218964d50cc 1795 Gene3D G3DSA:2.130.10.10 1466 1757 1.6E-43 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS02635 9a6b062adf266272f1af8218964d50cc 1795 SUPERFAMILY SSF51004 1467 1756 9.42E-42 T 06-07-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain SMD11_RS07345 ef91b7c95b5a787bcefea679af146663 156 SUPERFAMILY SSF52402 5 151 1.6E-19 T 06-07-2017 SMD11_RS07345 ef91b7c95b5a787bcefea679af146663 156 Gene3D G3DSA:3.40.50.620 66 152 1.4E-10 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SMD11_RS31000 a33a5f36407e0011eeb901dc769f8da5 297 Pfam PF03640 Secreted repeat of unknown function 104 139 1.4E-11 T 06-07-2017 IPR005297 Lipoprotein repeat SMD11_RS31000 a33a5f36407e0011eeb901dc769f8da5 297 Pfam PF03640 Secreted repeat of unknown function 159 198 9.5E-17 T 06-07-2017 IPR005297 Lipoprotein repeat SMD11_RS31000 a33a5f36407e0011eeb901dc769f8da5 297 Gene3D G3DSA:2.60.20.10 222 294 7.3E-6 T 06-07-2017 SMD11_RS31810 34ad68704e8aea5407815dcbf0187652 140 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 11 139 1.4E-24 T 06-07-2017 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like SMD11_RS31810 34ad68704e8aea5407815dcbf0187652 140 Gene3D G3DSA:3.10.490.10 10 138 4.0E-25 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like SMD11_RS31810 34ad68704e8aea5407815dcbf0187652 140 SUPERFAMILY SSF110857 9 138 2.09E-21 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like SMD11_RS27720 a3af42ecc59bc3e1a1c7087359658a6f 452 SUPERFAMILY SSF56349 171 438 2.83E-26 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD11_RS27720 a3af42ecc59bc3e1a1c7087359658a6f 452 Gene3D G3DSA:1.10.443.10 237 439 8.0E-20 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS27720 a3af42ecc59bc3e1a1c7087359658a6f 452 Pfam PF00589 Phage integrase family 238 433 3.9E-5 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS10520 1b4db42fdde28d7c82c8fe9580efb940 842 Pfam PF02687 FtsX-like permease family 719 834 5.1E-19 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 SMD11_RS10520 1b4db42fdde28d7c82c8fe9580efb940 842 Pfam PF02687 FtsX-like permease family 268 388 2.6E-24 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 SMD11_RS10520 1b4db42fdde28d7c82c8fe9580efb940 842 Pfam PF12704 MacB-like periplasmic core domain 17 231 7.8E-15 T 06-07-2017 IPR025857 MacB-like periplasmic core domain SMD11_RS10520 1b4db42fdde28d7c82c8fe9580efb940 842 Pfam PF12704 MacB-like periplasmic core domain 489 683 1.2E-6 T 06-07-2017 IPR025857 MacB-like periplasmic core domain SMD11_RS16510 fa4cc96a07f6410084fe6e56e756432f 308 Pfam PF10118 Predicted metal-dependent hydrolase 17 279 4.8E-76 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 SMD11_RS16510 fa4cc96a07f6410084fe6e56e756432f 308 PIRSF PIRSF007580 1 299 5.2E-114 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 SMD11_RS04745 1d254ab7af8a93ec3ef35720539b858b 172 SUPERFAMILY SSF55961 13 169 3.12E-23 T 06-07-2017 SMD11_RS04745 1d254ab7af8a93ec3ef35720539b858b 172 Gene3D G3DSA:3.30.530.20 11 121 1.2E-14 T 06-07-2017 IPR023393 START-like domain SMD11_RS04745 1d254ab7af8a93ec3ef35720539b858b 172 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 14 167 5.1E-14 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase SMD11_RS20895 e53a4a8ae2fa4ab7c30aea4b02c18b6a 293 SUPERFAMILY SSF161098 22 293 5.7E-65 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS20895 e53a4a8ae2fa4ab7c30aea4b02c18b6a 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 279 6.0E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS20895 e53a4a8ae2fa4ab7c30aea4b02c18b6a 293 Gene3D G3DSA:1.10.3720.10 23 281 1.0E-57 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS10575 163ae73bac3fb1d43c406f0b4bf6aca7 472 PRINTS PR01217 Proline rich extensin signature 272 288 4.0E-9 T 06-07-2017 SMD11_RS10575 163ae73bac3fb1d43c406f0b4bf6aca7 472 PRINTS PR01217 Proline rich extensin signature 184 196 4.0E-9 T 06-07-2017 SMD11_RS10575 163ae73bac3fb1d43c406f0b4bf6aca7 472 PRINTS PR01217 Proline rich extensin signature 298 315 4.0E-9 T 06-07-2017 SMD11_RS10575 163ae73bac3fb1d43c406f0b4bf6aca7 472 PRINTS PR01217 Proline rich extensin signature 417 429 4.0E-9 T 06-07-2017 SMD11_RS10575 163ae73bac3fb1d43c406f0b4bf6aca7 472 PRINTS PR01217 Proline rich extensin signature 226 238 4.0E-9 T 06-07-2017 SMD11_RS06635 c6d7341c0dfa636e954112f02438dc5e 280 Pfam PF00795 Carbon-nitrogen hydrolase 6 261 2.0E-66 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS06635 c6d7341c0dfa636e954112f02438dc5e 280 Gene3D G3DSA:3.60.110.10 4 278 2.2E-86 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS06635 c6d7341c0dfa636e954112f02438dc5e 280 SUPERFAMILY SSF56317 3 277 1.57E-79 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 SMD11_RS13505 6334b49eb03e6f1c97ca87916e2694c4 427 Gene3D G3DSA:3.40.390.10 182 245 7.2E-4 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD11_RS13505 6334b49eb03e6f1c97ca87916e2694c4 427 Pfam PF09471 IgA Peptidase M64 74 327 6.8E-70 T 06-07-2017 IPR019026 Peptidase M64, IgA SMD11_RS18495 96674941a43508a9f209cfb6cc9692f1 610 SUPERFAMILY SSF56112 11 263 2.7E-63 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS18495 96674941a43508a9f209cfb6cc9692f1 610 SMART SM00220 15 266 4.1E-42 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS18495 96674941a43508a9f209cfb6cc9692f1 610 Gene3D G3DSA:1.10.510.10 98 261 3.8E-39 T 06-07-2017 SMD11_RS18495 96674941a43508a9f209cfb6cc9692f1 610 Gene3D G3DSA:3.30.200.20 7 79 5.7E-15 T 06-07-2017 SMD11_RS18495 96674941a43508a9f209cfb6cc9692f1 610 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS18495 96674941a43508a9f209cfb6cc9692f1 610 Pfam PF00069 Protein kinase domain 15 261 5.5E-36 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS18495 96674941a43508a9f209cfb6cc9692f1 610 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SMD11_RS03145 c8d05a07c33a86f101760aca6348ba0a 182 Pfam PF13581 Histidine kinase-like ATPase domain 14 127 2.2E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS03145 c8d05a07c33a86f101760aca6348ba0a 182 SUPERFAMILY SSF55874 32 128 1.46E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS03145 c8d05a07c33a86f101760aca6348ba0a 182 Gene3D G3DSA:3.30.565.10 46 130 2.1E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS27575 759d3998d589e0c6db5f576d707f492b 220 SUPERFAMILY SSF55073 36 183 9.81E-31 T 06-07-2017 IPR029787 Nucleotide cyclase SMD11_RS27575 759d3998d589e0c6db5f576d707f492b 220 Gene3D G3DSA:3.30.70.270 32 183 1.5E-37 T 06-07-2017 SMD11_RS27575 759d3998d589e0c6db5f576d707f492b 220 SMART SM00267 20 188 6.1E-33 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS27575 759d3998d589e0c6db5f576d707f492b 220 Pfam PF00990 Diguanylate cyclase, GGDEF domain 31 183 3.7E-30 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS27575 759d3998d589e0c6db5f576d707f492b 220 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 30 183 3.1E-26 T 06-07-2017 IPR000160 GGDEF domain SMD11_RS23735 941cf2723e684626fd43afa7ebb5c3f0 495 SUPERFAMILY SSF56300 123 465 1.8E-28 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS23735 941cf2723e684626fd43afa7ebb5c3f0 495 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 13 111 1.4E-31 T 06-07-2017 IPR032093 Phospholipase D, N-terminal SMD11_RS23735 941cf2723e684626fd43afa7ebb5c3f0 495 Gene3D G3DSA:3.60.21.10 122 469 1.5E-14 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS23735 941cf2723e684626fd43afa7ebb5c3f0 495 Pfam PF09423 PhoD-like phosphatase 124 464 1.2E-106 T 06-07-2017 IPR018946 Alkaline phosphatase D-related SMD11_RS31960 89ce40143c08b0ba556d2a6676d37af6 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.6E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS31960 89ce40143c08b0ba556d2a6676d37af6 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.6E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS31960 89ce40143c08b0ba556d2a6676d37af6 207 SUPERFAMILY SSF48498 89 198 1.29E-14 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS31960 89ce40143c08b0ba556d2a6676d37af6 207 Gene3D G3DSA:1.10.357.10 18 200 1.6E-43 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS31960 89ce40143c08b0ba556d2a6676d37af6 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 2.4E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS31960 89ce40143c08b0ba556d2a6676d37af6 207 SUPERFAMILY SSF46689 14 92 1.74E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS14205 4af3ae12068061724e9b899126036b26 431 Gene3D G3DSA:1.20.1250.20 19 199 5.8E-26 T 06-07-2017 SMD11_RS14205 4af3ae12068061724e9b899126036b26 431 Gene3D G3DSA:1.20.1250.20 226 404 2.3E-18 T 06-07-2017 SMD11_RS14205 4af3ae12068061724e9b899126036b26 431 Pfam PF07690 Major Facilitator Superfamily 25 240 2.3E-25 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS14205 4af3ae12068061724e9b899126036b26 431 SUPERFAMILY SSF103473 18 404 1.96E-56 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS25520 f58cf10e88fa4afe96a39933148cabf9 147 Pfam PF04341 Protein of unknown function, DUF485 54 140 6.8E-30 T 06-07-2017 IPR007436 Protein of unknown function DUF485 SMD11_RS21765 5678c54878dc4f8ea17a13ba7d5506f3 264 Pfam PF15698 Phosphatase 13 262 2.8E-110 T 06-07-2017 IPR031423 Uncharacterised phosphatase SCO2771 SMD11_RS28505 b4d9563776001ea3b3adef6435e1a3a8 224 Pfam PF09335 SNARE associated Golgi protein 32 161 8.4E-21 T 06-07-2017 IPR032816 SNARE associated Golgi protein SMD11_RS02885 f7485574a624ada95f4d8832079bacdb 228 Pfam PF09335 SNARE associated Golgi protein 49 179 2.3E-19 T 06-07-2017 IPR032816 SNARE associated Golgi protein SMD11_RS13780 dcaeac48fed1890ef14a7b502889eff3 63 Pfam PF06348 Protein of unknown function (DUF1059) 7 54 8.8E-10 T 06-07-2017 IPR009409 Protein of unknown function DUF1059 SMD11_RS17390 143a2f81eab0149571e98e95240d458f 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 5.4E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS17390 143a2f81eab0149571e98e95240d458f 209 Gene3D G3DSA:1.10.357.10 3 189 6.8E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS17390 143a2f81eab0149571e98e95240d458f 209 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SMD11_RS17390 143a2f81eab0149571e98e95240d458f 209 SUPERFAMILY SSF46689 5 84 1.49E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS17390 143a2f81eab0149571e98e95240d458f 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 6.3E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS17390 143a2f81eab0149571e98e95240d458f 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 6.3E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS23915 0e05e9746d337a5f55f380a3aa144506 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 1.6E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS23915 0e05e9746d337a5f55f380a3aa144506 232 Gene3D G3DSA:1.10.357.10 6 203 5.1E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS23915 0e05e9746d337a5f55f380a3aa144506 232 SUPERFAMILY SSF46689 6 78 4.1E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS30660 0565fa3230152e329d71a6eb5f81d55a 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 5.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS30660 0565fa3230152e329d71a6eb5f81d55a 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 5.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS30660 0565fa3230152e329d71a6eb5f81d55a 207 Gene3D G3DSA:1.10.10.60 9 60 3.6E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS30660 0565fa3230152e329d71a6eb5f81d55a 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 63 2.5E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS30660 0565fa3230152e329d71a6eb5f81d55a 207 Gene3D G3DSA:1.10.357.10 61 196 2.0E-38 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS30660 0565fa3230152e329d71a6eb5f81d55a 207 SUPERFAMILY SSF46689 11 64 1.05E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS08360 b2b23756b29e43536f90fa44415fe37b 328 SUPERFAMILY SSF55874 201 325 5.24E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS08360 b2b23756b29e43536f90fa44415fe37b 328 Gene3D G3DSA:3.30.565.10 186 326 2.1E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS11245 4500f6711c73f2ff4968220e430a36a2 322 SUPERFAMILY SSF111331 1 322 1.8E-53 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMD11_RS11245 4500f6711c73f2ff4968220e430a36a2 322 SMART SM00046 2 133 3.7E-9 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMD11_RS11245 4500f6711c73f2ff4968220e430a36a2 322 Gene3D G3DSA:3.40.50.10330 4 78 0.001 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 SMD11_RS11245 4500f6711c73f2ff4968220e430a36a2 322 Pfam PF00781 Diacylglycerol kinase catalytic domain 2 118 1.1E-26 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SMD11_RS26675 4212cee8a85b441661096895aa1d6356 401 Pfam PF01168 Alanine racemase, N-terminal domain 28 274 9.5E-14 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SMD11_RS26675 4212cee8a85b441661096895aa1d6356 401 Gene3D G3DSA:3.20.20.10 118 276 1.1E-7 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS26675 4212cee8a85b441661096895aa1d6356 401 SUPERFAMILY SSF51419 29 273 6.98E-17 T 06-07-2017 IPR029066 PLP-binding barrel SMD11_RS14540 5f5389a1cf1210774d85f92754df9393 174 Gene3D G3DSA:3.40.220.10 4 172 1.8E-59 T 06-07-2017 SMD11_RS14540 5f5389a1cf1210774d85f92754df9393 174 Pfam PF01661 Macro domain 20 137 6.2E-38 T 06-07-2017 IPR002589 Macro domain SMD11_RS14540 5f5389a1cf1210774d85f92754df9393 174 SUPERFAMILY SSF52949 3 172 4.04E-55 T 06-07-2017 SMD11_RS14540 5f5389a1cf1210774d85f92754df9393 174 SMART SM00506 3 137 8.1E-47 T 06-07-2017 IPR002589 Macro domain SMD11_RS05610 cef602ed89a052878c921a4ea3978805 283 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 23 261 1.5E-74 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 SMD11_RS05610 cef602ed89a052878c921a4ea3978805 283 SUPERFAMILY SSF53335 21 260 5.23E-67 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS05610 cef602ed89a052878c921a4ea3978805 283 Gene3D G3DSA:3.40.50.150 29 205 6.9E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS05610 cef602ed89a052878c921a4ea3978805 283 Pfam PF04072 Leucine carboxyl methyltransferase 25 190 2.7E-51 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 SMD11_RS05585 5594ba9cc85677825e3a2a35c6569adb 363 Pfam PF01757 Acyltransferase family 1 337 1.0E-29 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 SMD11_RS05520 bec6326de1c6743076a5f4d862edf5b7 365 SUPERFAMILY SSF110296 42 329 2.46E-34 T 06-07-2017 SMD11_RS05520 bec6326de1c6743076a5f4d862edf5b7 365 Gene3D G3DSA:2.130.10.140 61 338 4.3E-30 T 06-07-2017 SMD11_RS11720 38c72cd6cdb4727cf0a0506317923f09 248 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 32 216 3.5E-94 T 06-07-2017 SMD11_RS11720 38c72cd6cdb4727cf0a0506317923f09 248 Gene3D G3DSA:1.20.1260.10 36 160 1.3E-7 T 06-07-2017 IPR012347 Ferritin-related SMD11_RS11720 38c72cd6cdb4727cf0a0506317923f09 248 SUPERFAMILY SSF47240 38 159 3.11E-10 T 06-07-2017 IPR009078 Ferritin-like superfamily SMD11_RS09905 8b0a8a372261a15402207bfc376c6d38 179 Pfam PF05331 Protein of unknown function (DUF742) 67 179 5.3E-41 T 06-07-2017 IPR007995 Protein of unknown function DUF742 SMD11_RS29530 cc0c44ef9ee49c06280d5ee3e3254cf8 386 Gene3D G3DSA:3.20.20.70 20 375 1.6E-98 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS29530 cc0c44ef9ee49c06280d5ee3e3254cf8 386 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 27 372 6.5E-55 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SMD11_RS29530 cc0c44ef9ee49c06280d5ee3e3254cf8 386 SUPERFAMILY SSF51395 22 374 1.53E-95 T 06-07-2017 SMD11_RS01485 85aca42e7a7252c2a22af7fdef3c725b 161 Pfam PF03413 Peptidase propeptide and YPEB domain 89 148 2.8E-8 T 06-07-2017 IPR025711 PepSY domain SMD11_RS07565 58df46a983010ba732c0327dc78fe669 282 SUPERFAMILY SSF47413 10 68 2.17E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS07565 58df46a983010ba732c0327dc78fe669 282 Pfam PF13560 Helix-turn-helix domain 12 74 6.7E-16 T 06-07-2017 SMD11_RS07565 58df46a983010ba732c0327dc78fe669 282 SMART SM00530 16 71 3.2E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS07565 58df46a983010ba732c0327dc78fe669 282 Gene3D G3DSA:1.10.260.40 5 72 6.3E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS00425 2909e56bdedfbf996297dc591bbc376f 146 Pfam PF00583 Acetyltransferase (GNAT) family 54 124 5.8E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS00425 2909e56bdedfbf996297dc591bbc376f 146 Gene3D G3DSA:3.40.630.30 48 146 4.8E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS00425 2909e56bdedfbf996297dc591bbc376f 146 SUPERFAMILY SSF55729 49 146 5.49E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS11380 8e598956c29d5ec70899d319d6d325c4 397 Gene3D G3DSA:1.10.3210.10 249 357 1.0E-7 T 06-07-2017 IPR006674 HD domain SMD11_RS11380 8e598956c29d5ec70899d319d6d325c4 397 SUPERFAMILY SSF109604 248 391 1.43E-12 T 06-07-2017 SMD11_RS31725 b143cfb7f82a1d74ff21f1314439a5de 380 SUPERFAMILY SSF55486 150 314 1.5E-13 T 06-07-2017 SMD11_RS25500 65b676310d664a3d94edabfbbe8cb6b9 299 Pfam PF04116 Fatty acid hydroxylase superfamily 88 220 9.7E-28 T 06-07-2017 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 SMD11_RS33830 22dca175b8bf5d8c9225557c4503a163 136 Gene3D G3DSA:3.30.750.24 1 89 4.2E-22 T 06-07-2017 IPR002645 STAS domain SMD11_RS33830 22dca175b8bf5d8c9225557c4503a163 136 Pfam PF13466 STAS domain 4 82 1.6E-16 T 06-07-2017 IPR002645 STAS domain SMD11_RS33830 22dca175b8bf5d8c9225557c4503a163 136 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 92 9.1E-18 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMD11_RS33830 22dca175b8bf5d8c9225557c4503a163 136 SUPERFAMILY SSF52091 1 91 8.44E-20 T 06-07-2017 IPR002645 STAS domain SMD11_RS14875 e37acef4f72467cfe5cce723f48ba241 397 SUPERFAMILY SSF55874 272 391 1.64E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14875 e37acef4f72467cfe5cce723f48ba241 397 Gene3D G3DSA:3.30.565.10 281 394 3.4E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14875 e37acef4f72467cfe5cce723f48ba241 397 Pfam PF07730 Histidine kinase 185 250 2.7E-21 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS14165 a60c4f56edb6570d390721f4fb443914 198 SUPERFAMILY SSF110087 55 161 1.01E-5 T 06-07-2017 IPR007410 DR1885-like metal-binding protein SMD11_RS18490 5ec26a6a3ac1f6aa00013c449b152c6f 369 SUPERFAMILY SSF53474 107 360 6.87E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS18490 5ec26a6a3ac1f6aa00013c449b152c6f 369 Pfam PF00756 Putative esterase 120 313 5.7E-13 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 SMD11_RS18490 5ec26a6a3ac1f6aa00013c449b152c6f 369 Gene3D G3DSA:3.40.50.1820 91 361 5.2E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01145 5238deb460e2d328ea52e9d3fd726837 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01145 5238deb460e2d328ea52e9d3fd726837 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01145 5238deb460e2d328ea52e9d3fd726837 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01145 5238deb460e2d328ea52e9d3fd726837 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS01145 5238deb460e2d328ea52e9d3fd726837 269 SUPERFAMILY SSF51735 9 237 1.7E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS01145 5238deb460e2d328ea52e9d3fd726837 269 Gene3D G3DSA:3.40.50.720 8 237 9.3E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS01145 5238deb460e2d328ea52e9d3fd726837 269 Pfam PF00106 short chain dehydrogenase 10 154 2.4E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS11815 145cf9ef77f4471b25de8cde1226342b 148 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 146 13.438 T 06-07-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 SMD11_RS11815 145cf9ef77f4471b25de8cde1226342b 148 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 1.0E-8 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 SMD11_RS11815 145cf9ef77f4471b25de8cde1226342b 148 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 1.0E-8 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 SMD11_RS11815 145cf9ef77f4471b25de8cde1226342b 148 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 1.0E-8 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 SMD11_RS11815 145cf9ef77f4471b25de8cde1226342b 148 Pfam PF02416 mttA/Hcf106 family 4 48 1.4E-5 T 06-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 SMD11_RS19330 69825d410bde04317d78833928a1b51d 308 SUPERFAMILY SSF102198 91 307 4.97E-24 T 06-07-2017 SMD11_RS19330 69825d410bde04317d78833928a1b51d 308 Gene3D G3DSA:3.50.30.50 87 307 6.3E-32 T 06-07-2017 SMD11_RS19330 69825d410bde04317d78833928a1b51d 308 Pfam PF04199 Putative cyclase 88 239 7.1E-24 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 SMD11_RS03620 a6b68cce1532196e426437f58428d259 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 1.5E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS03620 a6b68cce1532196e426437f58428d259 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 1.5E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS03620 a6b68cce1532196e426437f58428d259 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 1.5E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS03620 a6b68cce1532196e426437f58428d259 253 Pfam PF00561 alpha/beta hydrolase fold 26 130 2.2E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS03620 a6b68cce1532196e426437f58428d259 253 SUPERFAMILY SSF53474 12 249 1.33E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS03620 a6b68cce1532196e426437f58428d259 253 Gene3D G3DSA:3.40.50.1820 12 249 1.9E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS10640 1ce13a84b4c03bf4517769fc09c5581d 254 Pfam PF01987 Mitochondrial biogenesis AIM24 29 209 1.4E-9 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 SMD11_RS10640 1ce13a84b4c03bf4517769fc09c5581d 254 Gene3D G3DSA:3.60.160.10 23 216 2.7E-20 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 SMD11_RS10640 1ce13a84b4c03bf4517769fc09c5581d 254 SUPERFAMILY SSF51219 22 210 9.16E-28 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMD11_RS09650 3a78bda7eb03eae079b41b67a626d1b0 223 SMART SM00943 28 209 8.8E-26 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD11_RS09650 3a78bda7eb03eae079b41b67a626d1b0 223 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 30 201 7.6E-15 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD11_RS28235 6ce1d9d92e699caaff1a95426f69d020 196 SUPERFAMILY SSF81923 109 178 3.4E-7 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS28235 6ce1d9d92e699caaff1a95426f69d020 196 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 119 168 9.5E-5 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS28235 6ce1d9d92e699caaff1a95426f69d020 196 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 30 62 0.0069 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS28235 6ce1d9d92e699caaff1a95426f69d020 196 Gene3D G3DSA:1.10.1780.10 108 186 5.2E-12 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS28235 6ce1d9d92e699caaff1a95426f69d020 196 Gene3D G3DSA:1.10.1780.10 17 60 7.9E-6 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS17270 b8dfa2d4c7e97c058c3eb9d2c8d7b5e9 276 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 17 155 2.8E-16 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD11_RS17270 b8dfa2d4c7e97c058c3eb9d2c8d7b5e9 276 Pfam PF07398 MDMPI C-terminal domain 172 266 2.6E-7 T 06-07-2017 IPR010872 MDMPI C-terminal SMD11_RS17270 b8dfa2d4c7e97c058c3eb9d2c8d7b5e9 276 Gene3D G3DSA:1.20.120.450 6 157 7.6E-9 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase SMD11_RS17270 b8dfa2d4c7e97c058c3eb9d2c8d7b5e9 276 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 246 7.4E-36 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD11_RS17270 b8dfa2d4c7e97c058c3eb9d2c8d7b5e9 276 SUPERFAMILY SSF109854 3 161 2.93E-26 T 06-07-2017 SMD11_RS00730 f4ebd5057e2de7f87ec6b7551408a773 169 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 86 5.6E-10 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS00730 f4ebd5057e2de7f87ec6b7551408a773 169 Gene3D G3DSA:3.10.180.10 6 116 8.3E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS00730 f4ebd5057e2de7f87ec6b7551408a773 169 SUPERFAMILY SSF54593 6 120 5.25E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS06935 e71760d23ece11b800dc4b6c8cdaa782 459 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 361 381 - T 06-07-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 SMD11_RS06935 e71760d23ece11b800dc4b6c8cdaa782 459 Pfam PF00860 Permease family 32 410 5.5E-90 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD11_RS06935 e71760d23ece11b800dc4b6c8cdaa782 459 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 29 445 1.2E-101 T 06-07-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 SMD11_RS06935 e71760d23ece11b800dc4b6c8cdaa782 459 TIGRFAM TIGR03173 pbuX: xanthine permease 37 448 8.3E-143 T 06-07-2017 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 SMD11_RS34150 6b6e9de53bdb828e655bb07117de1e0d 296 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 49 248 4.6E-12 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 SMD11_RS32470 4e41ac1823068b317a25590004875c50 182 Pfam PF01613 Flavin reductase like domain 18 167 1.0E-36 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS32470 4e41ac1823068b317a25590004875c50 182 SUPERFAMILY SSF50475 14 169 4.91E-44 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS32470 4e41ac1823068b317a25590004875c50 182 Gene3D G3DSA:2.30.110.10 9 165 1.1E-48 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS32470 4e41ac1823068b317a25590004875c50 182 SMART SM00903 18 166 6.9E-43 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS04485 59740c08c8c35bffa15ddc95987341e5 515 Gene3D G3DSA:1.20.1250.20 467 503 1.5E-15 T 06-07-2017 SMD11_RS04485 59740c08c8c35bffa15ddc95987341e5 515 Gene3D G3DSA:1.20.1250.20 261 419 1.5E-15 T 06-07-2017 SMD11_RS04485 59740c08c8c35bffa15ddc95987341e5 515 SUPERFAMILY SSF103473 467 494 1.57E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS04485 59740c08c8c35bffa15ddc95987341e5 515 SUPERFAMILY SSF103473 5 197 1.57E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS04485 59740c08c8c35bffa15ddc95987341e5 515 SUPERFAMILY SSF103473 248 419 1.57E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS04485 59740c08c8c35bffa15ddc95987341e5 515 Gene3D G3DSA:1.20.1250.20 7 189 1.1E-30 T 06-07-2017 SMD11_RS04485 59740c08c8c35bffa15ddc95987341e5 515 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 13 489 2.2E-77 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS04485 59740c08c8c35bffa15ddc95987341e5 515 Pfam PF07690 Major Facilitator Superfamily 16 409 4.0E-48 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS32200 3f58d9295598e144ed2a7845d0ba0fa8 402 SUPERFAMILY SSF103473 18 398 5.36E-47 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS32200 3f58d9295598e144ed2a7845d0ba0fa8 402 Gene3D G3DSA:1.20.1250.20 226 398 1.9E-11 T 06-07-2017 SMD11_RS32200 3f58d9295598e144ed2a7845d0ba0fa8 402 Gene3D G3DSA:1.20.1250.20 20 198 1.0E-18 T 06-07-2017 SMD11_RS32200 3f58d9295598e144ed2a7845d0ba0fa8 402 Pfam PF07690 Major Facilitator Superfamily 24 241 3.5E-20 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS03045 6c21a6ed276c5775b0588a2b37460042 311 SMART SM00706 254 292 270.0 T 06-07-2017 IPR006624 Beta-propeller repeat TECPR SMD11_RS03045 6c21a6ed276c5775b0588a2b37460042 311 SMART SM00706 208 246 19.0 T 06-07-2017 IPR006624 Beta-propeller repeat TECPR SMD11_RS03045 6c21a6ed276c5775b0588a2b37460042 311 SMART SM00706 162 200 65.0 T 06-07-2017 IPR006624 Beta-propeller repeat TECPR SMD11_RS03045 6c21a6ed276c5775b0588a2b37460042 311 SMART SM00706 70 108 230.0 T 06-07-2017 IPR006624 Beta-propeller repeat TECPR SMD11_RS03045 6c21a6ed276c5775b0588a2b37460042 311 SMART SM00706 116 154 40.0 T 06-07-2017 IPR006624 Beta-propeller repeat TECPR SMD11_RS03045 6c21a6ed276c5775b0588a2b37460042 311 SUPERFAMILY SSF89372 28 259 6.28E-41 T 06-07-2017 SMD11_RS24545 49037ea338486979d2992a8467a5d3df 200 Hamap MF_01197 Cell division protein SepF [sepF]. 2 191 22.607 T 06-07-2017 IPR023052 Cell division protein SepF GO:0090529 SMD11_RS24545 49037ea338486979d2992a8467a5d3df 200 Pfam PF04472 Protein of unknown function (DUF552) 112 183 3.1E-27 T 06-07-2017 IPR007561 Cell division protein SepF/SepF-related GO:0090529 SMD11_RS22180 1d62c7426eaefd38e9f01d8ac09f22cd 195 PIRSF PIRSF034110 23 192 2.4E-39 T 06-07-2017 IPR009593 Protein of unknown function DUF1203 SMD11_RS22180 1d62c7426eaefd38e9f01d8ac09f22cd 195 Pfam PF06718 Protein of unknown function (DUF1203) 63 190 2.8E-36 T 06-07-2017 IPR009593 Protein of unknown function DUF1203 SMD11_RS13485 e1c87df15171c4d6db2aa2b64ac14589 391 Pfam PF06224 Winged helix DNA-binding domain 36 371 3.0E-54 T 06-07-2017 IPR009351 Protein of unknown function DUF1006 SMD11_RS32395 793208b26b14c928e2785869a9899992 320 Gene3D G3DSA:2.120.10.30 6 221 1.6E-51 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS32395 793208b26b14c928e2785869a9899992 320 SUPERFAMILY SSF63829 3 219 1.11E-46 T 06-07-2017 SMD11_RS32395 793208b26b14c928e2785869a9899992 320 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 29 219 5.1E-17 T 06-07-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region SMD11_RS08075 1ea4a9cbfbac3600e669b2aa74a0c77a 171 Pfam PF05523 WxcM-like, C-terminal 39 165 2.2E-41 T 06-07-2017 IPR008894 WxcM-like, C-terminal MetaCyc: PWY-6953|MetaCyc: PWY-7688 SMD11_RS08075 1ea4a9cbfbac3600e669b2aa74a0c77a 171 SUPERFAMILY SSF51182 39 165 3.48E-32 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS34245 f658fe9c4dbefa675afde02b11083651 367 Pfam PF00589 Phage integrase family 168 349 3.1E-21 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS34245 f658fe9c4dbefa675afde02b11083651 367 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 38 115 1.9E-6 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SMD11_RS34245 f658fe9c4dbefa675afde02b11083651 367 Gene3D G3DSA:1.10.150.130 151 160 6.0E-4 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal SMD11_RS34245 f658fe9c4dbefa675afde02b11083651 367 Gene3D G3DSA:1.10.150.130 77 116 6.0E-4 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal SMD11_RS34245 f658fe9c4dbefa675afde02b11083651 367 Gene3D G3DSA:1.10.443.10 161 350 2.6E-35 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS34245 f658fe9c4dbefa675afde02b11083651 367 SUPERFAMILY SSF56349 31 351 7.95E-33 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SMD11_RS01675 99aff62970060cd23939d0d5e0b5fff2 503 Gene3D G3DSA:2.40.10.10 38 137 4.3E-5 T 06-07-2017 SMD11_RS01675 99aff62970060cd23939d0d5e0b5fff2 503 SUPERFAMILY SSF50494 27 239 1.07E-13 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS27900 8d9a0607e993aa1d32932d8bc3e2cfdb 137 Gene3D G3DSA:1.25.40.20 24 113 5.6E-22 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain SMD11_RS27900 8d9a0607e993aa1d32932d8bc3e2cfdb 137 SMART SM00248 84 113 0.034 T 06-07-2017 IPR002110 Ankyrin repeat GO:0005515 SMD11_RS27900 8d9a0607e993aa1d32932d8bc3e2cfdb 137 SMART SM00248 51 80 0.0097 T 06-07-2017 IPR002110 Ankyrin repeat GO:0005515 SMD11_RS27900 8d9a0607e993aa1d32932d8bc3e2cfdb 137 Pfam PF12796 Ankyrin repeats (3 copies) 27 112 8.6E-11 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain SMD11_RS27900 8d9a0607e993aa1d32932d8bc3e2cfdb 137 SUPERFAMILY SSF48403 26 131 7.93E-22 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain SMD11_RS23205 665d7bcf57de5346509a106a99a45ef5 394 Pfam PF13556 PucR C-terminal helix-turn-helix domain 326 383 8.7E-20 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain SMD11_RS16795 edb4b355482ac7c9b5545d295d2da48c 498 PIRSF PIRSF010361 10 469 3.6E-139 T 06-07-2017 IPR016570 Uncharacterised conserved protein UCP010361, membrane SMD11_RS16795 edb4b355482ac7c9b5545d295d2da48c 498 Pfam PF09594 Protein of unknown function (DUF2029) 143 355 3.0E-10 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 SMD11_RS25340 de62d53073c0a282b0d6ac41d08f9353 393 SUPERFAMILY SSF55874 273 388 6.95E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS25340 de62d53073c0a282b0d6ac41d08f9353 393 Pfam PF07730 Histidine kinase 192 256 4.5E-18 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS33685 b0ddc1dd847eb3129d04c614ff0d6032 528 SUPERFAMILY SSF50923 28 218 1.31E-18 T 06-07-2017 IPR000585 Hemopexin-like domain SMD11_RS33685 b0ddc1dd847eb3129d04c614ff0d6032 528 SUPERFAMILY SSF51004 231 525 9.68E-43 T 06-07-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain SMD11_RS33685 b0ddc1dd847eb3129d04c614ff0d6032 528 Gene3D G3DSA:2.110.10.10 28 220 3.4E-21 T 06-07-2017 IPR000585 Hemopexin-like domain SMD11_RS33685 b0ddc1dd847eb3129d04c614ff0d6032 528 Gene3D G3DSA:2.130.10.10 221 338 2.3E-13 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS33685 b0ddc1dd847eb3129d04c614ff0d6032 528 Gene3D G3DSA:2.130.10.10 341 512 8.5E-28 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS02495 e19f868c4c607aa381f7d365c0b53c8d 180 SUPERFAMILY SSF55961 15 134 1.97E-16 T 06-07-2017 SMD11_RS02495 e19f868c4c607aa381f7d365c0b53c8d 180 Gene3D G3DSA:3.30.530.20 14 133 1.4E-13 T 06-07-2017 IPR023393 START-like domain SMD11_RS02495 e19f868c4c607aa381f7d365c0b53c8d 180 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 15 133 8.9E-15 T 06-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain SMD11_RS20850 6100b583aaca6d9609e7c336a07cc7c7 168 SUPERFAMILY SSF103473 16 131 5.75E-5 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS20850 6100b583aaca6d9609e7c336a07cc7c7 168 Pfam PF04138 GtrA-like protein 9 129 3.8E-20 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 SMD11_RS31895 0a1b4eaf5a8d921a8a828b1ef75164d5 364 SUPERFAMILY SSF81606 221 361 8.89E-6 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS31895 0a1b4eaf5a8d921a8a828b1ef75164d5 364 SMART SM00331 148 362 3.1E-38 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS31895 0a1b4eaf5a8d921a8a828b1ef75164d5 364 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 176 361 2.3E-43 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS30850 1006ec02333ec07c84d79821a9b8bd2e 789 Pfam PF05729 NACHT domain 205 370 1.3E-8 T 06-07-2017 SMD11_RS22150 1b946eb978799c47c6861286b55299cc 706 SUPERFAMILY SSF51445 610 686 2.18E-134 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS22150 1b946eb978799c47c6861286b55299cc 706 SUPERFAMILY SSF51445 147 581 2.18E-134 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS22150 1b946eb978799c47c6861286b55299cc 706 Gene3D G3DSA:3.20.20.80 145 669 8.0E-158 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS22150 1b946eb978799c47c6861286b55299cc 706 Pfam PF02446 4-alpha-glucanotransferase 153 664 1.9E-113 T 06-07-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMD11_RS22150 1b946eb978799c47c6861286b55299cc 706 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 111 665 2.0E-88 T 06-07-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SMD11_RS11410 ade59d130bab9d626d0d55987ab0dd3e 237 Pfam PF13398 Peptidase M50B-like 27 228 1.4E-58 T 06-07-2017 SMD11_RS02385 6880f6d2847215de98382d51b8339bda 520 Gene3D G3DSA:3.40.50.1820 198 322 5.1E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS02385 6880f6d2847215de98382d51b8339bda 520 Gene3D G3DSA:3.40.50.1820 74 158 5.1E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS02385 6880f6d2847215de98382d51b8339bda 520 Gene3D G3DSA:3.40.50.1820 389 506 5.1E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS02385 6880f6d2847215de98382d51b8339bda 520 Pfam PF00561 alpha/beta hydrolase fold 110 488 8.4E-24 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS02385 6880f6d2847215de98382d51b8339bda 520 SUPERFAMILY SSF53474 200 254 2.92E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS02385 6880f6d2847215de98382d51b8339bda 520 SUPERFAMILY SSF53474 362 485 2.92E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS02385 6880f6d2847215de98382d51b8339bda 520 SUPERFAMILY SSF53474 109 159 2.92E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12310 c395f488857c1086b8d5ac08fe15d308 232 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 15 61 2.7E-7 T 06-07-2017 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal SMD11_RS33720 89edbc53de09110b0dc9b73a402d1082 333 SUPERFAMILY SSF50974 12 255 6.28E-14 T 06-07-2017 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 SMD11_RS33720 89edbc53de09110b0dc9b73a402d1082 333 Gene3D G3DSA:2.130.10.10 23 211 3.6E-8 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS06475 ae2f74c81452ba64f9bd3c454072be75 205 SMART SM00567 E-Z type HEAT repeats 93 122 230.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD11_RS06475 ae2f74c81452ba64f9bd3c454072be75 205 SMART SM00567 E-Z type HEAT repeats 162 191 1.9 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD11_RS06475 ae2f74c81452ba64f9bd3c454072be75 205 SMART SM00567 E-Z type HEAT repeats 62 91 19.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 SMD11_RS06475 ae2f74c81452ba64f9bd3c454072be75 205 SUPERFAMILY SSF48371 51 203 1.27E-7 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 SMD11_RS06475 ae2f74c81452ba64f9bd3c454072be75 205 Gene3D G3DSA:1.25.10.10 142 204 2.1E-8 T 06-07-2017 IPR011989 Armadillo-like helical SMD11_RS06475 ae2f74c81452ba64f9bd3c454072be75 205 Gene3D G3DSA:1.25.10.10 65 109 2.1E-8 T 06-07-2017 IPR011989 Armadillo-like helical SMD11_RS04290 aad5a993ec257dfcf9da955e0a0f9e6c 420 SUPERFAMILY SSF53300 38 224 1.91E-24 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS04290 aad5a993ec257dfcf9da955e0a0f9e6c 420 Pfam PF13519 von Willebrand factor type A domain 40 156 7.6E-11 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS04290 aad5a993ec257dfcf9da955e0a0f9e6c 420 Gene3D G3DSA:3.40.50.410 40 223 1.1E-14 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS04290 aad5a993ec257dfcf9da955e0a0f9e6c 420 SMART SM00327 37 227 3.6E-16 T 06-07-2017 IPR002035 von Willebrand factor, type A SMD11_RS10590 93060899d36eb1eb8fda61012efc55c0 325 Pfam PF14561 Tetratricopeptide repeat 239 325 4.3E-23 T 06-07-2017 SMD11_RS10590 93060899d36eb1eb8fda61012efc55c0 325 Gene3D G3DSA:1.25.40.10 242 325 3.8E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS10590 93060899d36eb1eb8fda61012efc55c0 325 Gene3D G3DSA:3.40.30.10 50 153 2.0E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS10590 93060899d36eb1eb8fda61012efc55c0 325 ProSitePatterns PS00194 Thioredoxin family active site. 71 89 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 SMD11_RS10590 93060899d36eb1eb8fda61012efc55c0 325 SUPERFAMILY SSF52833 41 154 5.68E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS10590 93060899d36eb1eb8fda61012efc55c0 325 Pfam PF00085 Thioredoxin 52 151 2.0E-22 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 SMD11_RS10590 93060899d36eb1eb8fda61012efc55c0 325 Pfam PF14559 Tetratricopeptide repeat 199 234 1.1E-6 T 06-07-2017 SMD11_RS10590 93060899d36eb1eb8fda61012efc55c0 325 Gene3D G3DSA:1.25.40.10 188 234 3.0E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS12295 438b35dff0ba9ebf65c1f9e5f3336718 283 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 34 103 1.7E-7 T 06-07-2017 IPR025159 Transcriptional regulator, AbiEi antitoxin SMD11_RS31630 af4d12d8c2f1fc580c787cba70c443f4 486 Pfam PF07690 Major Facilitator Superfamily 34 423 2.0E-50 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS31630 af4d12d8c2f1fc580c787cba70c443f4 486 Gene3D G3DSA:1.20.1250.20 278 480 3.6E-20 T 06-07-2017 SMD11_RS31630 af4d12d8c2f1fc580c787cba70c443f4 486 Gene3D G3DSA:1.20.1250.20 27 208 6.5E-27 T 06-07-2017 SMD11_RS31630 af4d12d8c2f1fc580c787cba70c443f4 486 SUPERFAMILY SSF103473 16 211 4.58E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS31630 af4d12d8c2f1fc580c787cba70c443f4 486 SUPERFAMILY SSF103473 262 476 4.58E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS03480 093e7045da1122f7bf61bdb300ab74ef 225 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 61 70 - T 06-07-2017 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS03480 093e7045da1122f7bf61bdb300ab74ef 225 Gene3D G3DSA:3.40.470.10 6 224 1.7E-79 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS03480 093e7045da1122f7bf61bdb300ab74ef 225 SUPERFAMILY SSF52141 9 224 2.18E-70 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS03480 093e7045da1122f7bf61bdb300ab74ef 225 Pfam PF03167 Uracil DNA glycosylase superfamily 55 211 4.4E-17 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS03480 093e7045da1122f7bf61bdb300ab74ef 225 SMART SM00987 53 212 4.5E-29 T 06-07-2017 SMD11_RS03480 093e7045da1122f7bf61bdb300ab74ef 225 SMART SM00986 53 212 4.5E-29 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS03480 093e7045da1122f7bf61bdb300ab74ef 225 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 11 223 33.256 T 06-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SMD11_RS16140 5ff927edda981cc839c1379455837df8 159 Gene3D G3DSA:3.30.350.10 51 146 1.8E-28 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 SMD11_RS16140 5ff927edda981cc839c1379455837df8 159 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 68 140 4.0E-11 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 SMD11_RS16140 5ff927edda981cc839c1379455837df8 159 Pfam PF00720 Subtilisin inhibitor-like 53 131 5.4E-10 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 SMD11_RS16140 5ff927edda981cc839c1379455837df8 159 SUPERFAMILY SSF55399 51 146 1.57E-23 T 06-07-2017 IPR023549 Subtilisin inhibitor GO:0004867 SMD11_RS21905 4d515fd5f6a98507fa358f9df4542fb3 175 Pfam PF03703 Bacterial PH domain 85 161 1.4E-13 T 06-07-2017 IPR005182 Domain of unknown function DUF304 SMD11_RS15915 b8c421e1248f1fe7d9ef0a7207ab2a3c 180 Gene3D G3DSA:3.30.530.20 15 160 1.2E-7 T 06-07-2017 IPR023393 START-like domain SMD11_RS15915 b8c421e1248f1fe7d9ef0a7207ab2a3c 180 SUPERFAMILY SSF55961 14 179 6.32E-13 T 06-07-2017 SMD11_RS15915 b8c421e1248f1fe7d9ef0a7207ab2a3c 180 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 15 177 4.1E-10 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase SMD11_RS26940 914e9b10aa80ed585931e63d37ad9d3a 390 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 62 379 3.4E-44 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SMD11_RS26940 914e9b10aa80ed585931e63d37ad9d3a 390 Gene3D G3DSA:3.20.20.190 57 381 1.4E-93 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD11_RS26940 914e9b10aa80ed585931e63d37ad9d3a 390 SUPERFAMILY SSF51695 56 380 1.23E-80 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SMD11_RS24945 a0b18fd32251a80beab819ffb1b23ec6 762 Gene3D G3DSA:3.40.50.740 396 629 1.9E-56 T 06-07-2017 SMD11_RS24945 a0b18fd32251a80beab819ffb1b23ec6 762 Gene3D G3DSA:3.40.50.740 120 193 1.9E-56 T 06-07-2017 SMD11_RS24945 a0b18fd32251a80beab819ffb1b23ec6 762 PIRSF PIRSF000144 6 760 0.0 T 06-07-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 SMD11_RS24945 a0b18fd32251a80beab819ffb1b23ec6 762 Pfam PF00384 Molybdopterin oxidoreductase 120 492 3.9E-31 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS24945 a0b18fd32251a80beab819ffb1b23ec6 762 SUPERFAMILY SSF50692 636 757 1.9E-17 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain SMD11_RS24945 a0b18fd32251a80beab819ffb1b23ec6 762 SUPERFAMILY SSF53706 58 632 3.14E-146 T 06-07-2017 SMD11_RS24945 a0b18fd32251a80beab819ffb1b23ec6 762 Gene3D G3DSA:3.40.228.10 194 395 5.8E-54 T 06-07-2017 SMD11_RS24945 a0b18fd32251a80beab819ffb1b23ec6 762 Pfam PF01568 Molydopterin dinucleotide binding domain 643 749 2.1E-9 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 SMD11_RS24945 a0b18fd32251a80beab819ffb1b23ec6 762 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 756 9.1E-294 T 06-07-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 SMD11_RS24945 a0b18fd32251a80beab819ffb1b23ec6 762 Gene3D G3DSA:2.40.40.20 632 757 1.6E-11 T 06-07-2017 SMD11_RS22270 4dcdf42f63185fda26bfc78682912b92 379 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 196 378 1.6E-30 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS22270 4dcdf42f63185fda26bfc78682912b92 379 SMART SM00331 169 378 4.5E-10 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SMD11_RS04870 eb28a186bb57796c686e577d0031b6b7 425 Gene3D G3DSA:3.30.565.10 328 423 2.2E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS04870 eb28a186bb57796c686e577d0031b6b7 425 SUPERFAMILY SSF55874 302 420 4.96E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS04870 eb28a186bb57796c686e577d0031b6b7 425 Pfam PF07730 Histidine kinase 219 284 1.7E-15 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS22980 28ee59cc7af0cf89b843cdf361e15ee1 261 Pfam PF01925 Sulfite exporter TauE/SafE 14 252 5.6E-36 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 SMD11_RS04215 0f3eb688fd866c107dda382bf8a7352e 379 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 72 352 1.2E-113 T 06-07-2017 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 SMD11_RS04215 0f3eb688fd866c107dda382bf8a7352e 379 Pfam PF03824 High-affinity nickel-transport protein 70 356 2.4E-86 T 06-07-2017 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 SMD11_RS00950 1fcde6aa58f34955309c2612d65b9c4b 306 SUPERFAMILY SSF56601 50 300 3.06E-72 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS00950 1fcde6aa58f34955309c2612d65b9c4b 306 Pfam PF13354 Beta-lactamase enzyme family 72 277 1.2E-37 T 06-07-2017 SMD11_RS00950 1fcde6aa58f34955309c2612d65b9c4b 306 PRINTS PR00118 Beta-lactamase class A signature 122 147 4.1E-67 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD11_RS00950 1fcde6aa58f34955309c2612d65b9c4b 306 PRINTS PR00118 Beta-lactamase class A signature 220 235 4.1E-67 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD11_RS00950 1fcde6aa58f34955309c2612d65b9c4b 306 PRINTS PR00118 Beta-lactamase class A signature 184 209 4.1E-67 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD11_RS00950 1fcde6aa58f34955309c2612d65b9c4b 306 PRINTS PR00118 Beta-lactamase class A signature 82 99 4.1E-67 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD11_RS00950 1fcde6aa58f34955309c2612d65b9c4b 306 PRINTS PR00118 Beta-lactamase class A signature 158 182 4.1E-67 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD11_RS00950 1fcde6aa58f34955309c2612d65b9c4b 306 PRINTS PR00118 Beta-lactamase class A signature 237 252 4.1E-67 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD11_RS00950 1fcde6aa58f34955309c2612d65b9c4b 306 PRINTS PR00118 Beta-lactamase class A signature 51 75 4.1E-67 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 SMD11_RS00950 1fcde6aa58f34955309c2612d65b9c4b 306 ProSitePatterns PS00146 Beta-lactamase class-A active site. 84 99 - T 06-07-2017 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 SMD11_RS00950 1fcde6aa58f34955309c2612d65b9c4b 306 Gene3D G3DSA:3.40.710.10 50 304 4.8E-101 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like SMD11_RS16160 dc04651059604ece46f01b2b34cae960 283 Gene3D G3DSA:2.40.180.10 15 272 5.1E-47 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS16160 dc04651059604ece46f01b2b34cae960 283 PRINTS PR00067 Catalase signature 93 111 1.4E-6 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS16160 dc04651059604ece46f01b2b34cae960 283 PRINTS PR00067 Catalase signature 52 70 1.4E-6 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS16160 dc04651059604ece46f01b2b34cae960 283 PRINTS PR00067 Catalase signature 15 37 1.4E-6 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS16160 dc04651059604ece46f01b2b34cae960 283 SMART SM01060 1 276 1.6E-5 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS16160 dc04651059604ece46f01b2b34cae960 283 SUPERFAMILY SSF56634 22 253 7.72E-46 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS16160 dc04651059604ece46f01b2b34cae960 283 Pfam PF00199 Catalase 21 251 2.6E-20 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 SMD11_RS02480 06b7d9ff85c498f857f34e29ed775feb 128 SUPERFAMILY SSF47090 60 126 9.68E-17 T 06-07-2017 IPR002477 Peptidoglycan binding-like SMD11_RS02480 06b7d9ff85c498f857f34e29ed775feb 128 Gene3D G3DSA:1.10.101.10 61 126 2.0E-19 T 06-07-2017 IPR002477 Peptidoglycan binding-like SMD11_RS02480 06b7d9ff85c498f857f34e29ed775feb 128 Pfam PF01471 Putative peptidoglycan binding domain 71 126 4.1E-15 T 06-07-2017 IPR002477 Peptidoglycan binding-like SMD11_RS14425 e021d9126d3e2bb2948bf645a5850f31 200 Pfam PF08768 Domain of unknown function (DUF1794) 12 164 3.8E-48 T 06-07-2017 IPR014878 Domain of unknown function DUF1794 SMD11_RS14425 e021d9126d3e2bb2948bf645a5850f31 200 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 4 166 32.378 T 06-07-2017 IPR022939 Uncharacterised protein family UPF0678 SMD11_RS14425 e021d9126d3e2bb2948bf645a5850f31 200 SUPERFAMILY SSF50814 7 165 9.93E-43 T 06-07-2017 IPR011038 Calycin-like SMD11_RS31740 fea36fd1dba9c7759db5cb0db3271ead 463 SUPERFAMILY SSF48452 221 420 1.19E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS31740 fea36fd1dba9c7759db5cb0db3271ead 463 Gene3D G3DSA:1.25.40.10 191 334 1.3E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS27530 e9aa805e6b04b27b2bb8693a51aee925 155 Pfam PF10756 Bacterial PH domain 72 142 5.2E-18 T 06-07-2017 IPR019692 Protein of unknown function DUF2581 SMD11_RS22945 8c66bcf6e8903ef77751118dc8e81632 347 Gene3D G3DSA:1.10.10.10 265 315 3.3E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS22945 8c66bcf6e8903ef77751118dc8e81632 347 Pfam PF12840 Helix-turn-helix domain 255 300 2.0E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS22945 8c66bcf6e8903ef77751118dc8e81632 347 SMART SM00418 246 317 0.0027 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SMD11_RS22945 8c66bcf6e8903ef77751118dc8e81632 347 SUPERFAMILY SSF46785 264 317 6.61E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13940 99beae180a1cd17e381105f2e4ca5f63 283 Gene3D G3DSA:3.40.50.1000 28 108 1.3E-34 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS13940 99beae180a1cd17e381105f2e4ca5f63 283 Gene3D G3DSA:3.40.50.1000 188 277 1.3E-34 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS13940 99beae180a1cd17e381105f2e4ca5f63 283 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 27 275 2.0E-31 T 06-07-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 SMD11_RS13940 99beae180a1cd17e381105f2e4ca5f63 283 SUPERFAMILY SSF56784 29 275 3.56E-35 T 06-07-2017 IPR023214 HAD-like domain SMD11_RS13940 99beae180a1cd17e381105f2e4ca5f63 283 Pfam PF02358 Trehalose-phosphatase 32 245 1.8E-25 T 06-07-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 SMD11_RS06440 9d88adfe7016279cd4dd19c6728e50e1 429 Gene3D G3DSA:3.50.50.60 335 379 1.6E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS06440 9d88adfe7016279cd4dd19c6728e50e1 429 Gene3D G3DSA:3.50.50.60 27 125 1.6E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS06440 9d88adfe7016279cd4dd19c6728e50e1 429 Gene3D G3DSA:3.50.50.60 170 246 1.6E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS06440 9d88adfe7016279cd4dd19c6728e50e1 429 Pfam PF01266 FAD dependent oxidoreductase 34 371 2.1E-48 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD11_RS06440 9d88adfe7016279cd4dd19c6728e50e1 429 SUPERFAMILY SSF51905 33 247 1.07E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS06440 9d88adfe7016279cd4dd19c6728e50e1 429 SUPERFAMILY SSF51905 335 400 1.07E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS32570 16f9108857ef3402890c3a0ef7bfc3ef 496 Gene3D G3DSA:3.10.20.70 31 137 3.5E-8 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS32570 16f9108857ef3402890c3a0ef7bfc3ef 496 Gene3D G3DSA:3.30.590.10 141 471 1.4E-73 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SMD11_RS32570 16f9108857ef3402890c3a0ef7bfc3ef 496 SUPERFAMILY SSF54368 32 136 3.92E-11 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS32570 16f9108857ef3402890c3a0ef7bfc3ef 496 Pfam PF00120 Glutamine synthetase, catalytic domain 140 490 2.4E-69 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS32570 16f9108857ef3402890c3a0ef7bfc3ef 496 SMART SM01230 137 404 1.4E-68 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SMD11_RS32570 16f9108857ef3402890c3a0ef7bfc3ef 496 SUPERFAMILY SSF55931 137 493 3.92E-79 T 06-07-2017 SMD11_RS08160 58cacca910ee7b7d5104f42ff915b3bf 332 SUPERFAMILY SSF51430 8 318 4.19E-87 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS08160 58cacca910ee7b7d5104f42ff915b3bf 332 Gene3D G3DSA:3.20.20.100 17 319 3.4E-86 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS08160 58cacca910ee7b7d5104f42ff915b3bf 332 Pfam PF00248 Aldo/keto reductase family 20 315 9.0E-66 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS12120 5ce3c46edbd2840fbb0af45f5a787597 253 SUPERFAMILY SSF53067 1 243 9.18E-39 T 06-07-2017 SMD11_RS12120 5ce3c46edbd2840fbb0af45f5a787597 253 Gene3D G3DSA:3.30.420.40 2 104 3.2E-42 T 06-07-2017 SMD11_RS12120 5ce3c46edbd2840fbb0af45f5a787597 253 Pfam PF00480 ROK family 4 160 8.7E-16 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 SMD11_RS12120 5ce3c46edbd2840fbb0af45f5a787597 253 Gene3D G3DSA:3.30.420.40 105 243 7.9E-40 T 06-07-2017 SMD11_RS01115 f986105224d1e199791c67fa6ba956a4 495 SUPERFAMILY SSF52091 418 492 3.73E-6 T 06-07-2017 IPR002645 STAS domain SMD11_RS01115 f986105224d1e199791c67fa6ba956a4 495 Pfam PF00916 Sulfate permease family 13 376 5.5E-59 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 SMD11_RS01115 f986105224d1e199791c67fa6ba956a4 495 Pfam PF13466 STAS domain 425 493 7.1E-7 T 06-07-2017 IPR002645 STAS domain SMD11_RS13540 f72c8172868e562f0c544697a9f34b05 411 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 129 280 2.8E-6 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD11_RS13540 f72c8172868e562f0c544697a9f34b05 411 Pfam PF13490 Putative zinc-finger 49 77 1.2E-5 T 06-07-2017 IPR027383 Putative zinc-finger SMD11_RS13540 f72c8172868e562f0c544697a9f34b05 411 SUPERFAMILY SSF109854 119 286 1.88E-15 T 06-07-2017 SMD11_RS13015 a6e46f6b7ffad6467da8f2753bbbfd03 214 SUPERFAMILY SSF46894 135 196 2.07E-14 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS13015 a6e46f6b7ffad6467da8f2753bbbfd03 214 SMART SM00448 1 120 2.6E-12 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS13015 a6e46f6b7ffad6467da8f2753bbbfd03 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 196 9.5E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13015 a6e46f6b7ffad6467da8f2753bbbfd03 214 SMART SM00421 148 210 1.4E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13015 a6e46f6b7ffad6467da8f2753bbbfd03 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 2.9E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13015 a6e46f6b7ffad6467da8f2753bbbfd03 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 2.9E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13015 a6e46f6b7ffad6467da8f2753bbbfd03 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 2.9E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS13015 a6e46f6b7ffad6467da8f2753bbbfd03 214 Gene3D G3DSA:1.10.10.10 149 213 6.6E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS13015 a6e46f6b7ffad6467da8f2753bbbfd03 214 SUPERFAMILY SSF52172 2 136 1.71E-18 T 06-07-2017 IPR011006 CheY-like superfamily SMD11_RS13015 a6e46f6b7ffad6467da8f2753bbbfd03 214 Gene3D G3DSA:3.40.50.2300 2 148 9.9E-25 T 06-07-2017 SMD11_RS13015 a6e46f6b7ffad6467da8f2753bbbfd03 214 Pfam PF00072 Response regulator receiver domain 3 108 3.5E-13 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SMD11_RS01315 4641502467619cbac135037a71a21e19 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 8.0E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS01315 4641502467619cbac135037a71a21e19 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 8.0E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS01315 4641502467619cbac135037a71a21e19 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 218 232 8.0E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS01315 4641502467619cbac135037a71a21e19 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 8.0E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS01315 4641502467619cbac135037a71a21e19 297 Pfam PF00561 alpha/beta hydrolase fold 30 260 1.1E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS01315 4641502467619cbac135037a71a21e19 297 Gene3D G3DSA:3.40.50.1820 6 272 6.8E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01315 4641502467619cbac135037a71a21e19 297 SUPERFAMILY SSF53474 6 272 7.82E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS28960 417c24f3e4f010cb98e6cc8e1b74a2b2 348 SUPERFAMILY SSF48452 65 277 1.06E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS28960 417c24f3e4f010cb98e6cc8e1b74a2b2 348 Pfam PF13424 Tetratricopeptide repeat 169 239 1.9E-11 T 06-07-2017 SMD11_RS28960 417c24f3e4f010cb98e6cc8e1b74a2b2 348 Pfam PF13432 Tetratricopeptide repeat 252 308 0.0024 T 06-07-2017 SMD11_RS28960 417c24f3e4f010cb98e6cc8e1b74a2b2 348 Gene3D G3DSA:1.25.40.10 47 285 6.9E-20 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS06785 ebae8881abc3a3d50ac211f623ec4f60 430 SUPERFAMILY SSF48452 142 232 5.15E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS06785 ebae8881abc3a3d50ac211f623ec4f60 430 Gene3D G3DSA:1.25.40.10 107 231 1.3E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS25750 113fe43d1d88f3885531077ee03629d7 115 SUPERFAMILY SSF55718 11 115 1.2E-12 T 06-07-2017 IPR003033 SCP2 sterol-binding domain SMD11_RS25750 113fe43d1d88f3885531077ee03629d7 115 Gene3D G3DSA:3.30.1050.10 9 115 2.1E-13 T 06-07-2017 IPR003033 SCP2 sterol-binding domain SMD11_RS33330 d2dc30e8df4a398f8409193e152ed948 251 Pfam PF01925 Sulfite exporter TauE/SafE 9 247 1.2E-33 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 SMD11_RS19915 48af26f1396a315f79dff6137f6edc9f 160 Gene3D G3DSA:3.40.630.30 8 145 5.6E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS19915 48af26f1396a315f79dff6137f6edc9f 160 Pfam PF00583 Acetyltransferase (GNAT) family 53 136 1.9E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS19915 48af26f1396a315f79dff6137f6edc9f 160 SUPERFAMILY SSF55729 9 148 1.38E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS26625 93b6813c4e72a6b503505c6f38064c15 245 SUPERFAMILY SSF53807 6 240 1.14E-29 T 06-07-2017 SMD11_RS26625 93b6813c4e72a6b503505c6f38064c15 245 Gene3D G3DSA:3.40.50.1980 126 197 6.2E-7 T 06-07-2017 SMD11_RS26625 93b6813c4e72a6b503505c6f38064c15 245 Gene3D G3DSA:3.40.50.1980 6 105 1.1E-20 T 06-07-2017 SMD11_RS23670 10aa16108d163b90475b021a7bdafc07 341 Gene3D G3DSA:3.40.50.1980 83 198 3.4E-21 T 06-07-2017 SMD11_RS23670 10aa16108d163b90475b021a7bdafc07 341 SUPERFAMILY SSF53807 67 337 9.81E-43 T 06-07-2017 SMD11_RS23670 10aa16108d163b90475b021a7bdafc07 341 Pfam PF01497 Periplasmic binding protein 84 312 5.2E-31 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SMD11_RS23670 10aa16108d163b90475b021a7bdafc07 341 Gene3D G3DSA:3.40.50.1980 202 337 2.8E-13 T 06-07-2017 SMD11_RS31720 bfdbd5d9fe9344915d7fc65cc53d628c 343 SUPERFAMILY SSF52540 147 259 1.65E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS31720 bfdbd5d9fe9344915d7fc65cc53d628c 343 Gene3D G3DSA:3.40.50.300 144 226 3.2E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS19010 0478ad6403b1f0167bc38c632efc622f 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 2.0E-9 T 06-07-2017 SMD11_RS19010 0478ad6403b1f0167bc38c632efc622f 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.021 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS19010 0478ad6403b1f0167bc38c632efc622f 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 9.0E-22 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS19010 0478ad6403b1f0167bc38c632efc622f 37 Pfam PF00444 Ribosomal protein L36 1 37 4.2E-18 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS19010 0478ad6403b1f0167bc38c632efc622f 37 SUPERFAMILY SSF57840 1 37 3.53E-16 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS19010 0478ad6403b1f0167bc38c632efc622f 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SMD11_RS19230 939350fd5dbd61a5b9d0552564c715b6 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 177 4.7E-4 T 06-07-2017 SMD11_RS19230 939350fd5dbd61a5b9d0552564c715b6 257 PIRSF PIRSF000126 1 254 2.6E-67 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19230 939350fd5dbd61a5b9d0552564c715b6 257 Pfam PF00106 short chain dehydrogenase 3 188 7.1E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19230 939350fd5dbd61a5b9d0552564c715b6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 3.2E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19230 939350fd5dbd61a5b9d0552564c715b6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.2E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19230 939350fd5dbd61a5b9d0552564c715b6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 3.2E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19230 939350fd5dbd61a5b9d0552564c715b6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 3.2E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19230 939350fd5dbd61a5b9d0552564c715b6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.2E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19230 939350fd5dbd61a5b9d0552564c715b6 257 SUPERFAMILY SSF51735 3 242 1.99E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS19230 939350fd5dbd61a5b9d0552564c715b6 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 7.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19230 939350fd5dbd61a5b9d0552564c715b6 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 7.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19230 939350fd5dbd61a5b9d0552564c715b6 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 7.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS19230 939350fd5dbd61a5b9d0552564c715b6 257 Gene3D G3DSA:3.40.50.720 3 217 1.6E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS07560 a5b7260fe33e16674ba2e838c70704b4 97 Pfam PF04149 Domain of unknown function (DUF397) 33 85 4.3E-13 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS14895 3386490aacb4564ac3fe302ffeb23d7a 326 Gene3D G3DSA:3.40.190.10 274 324 5.2E-42 T 06-07-2017 SMD11_RS14895 3386490aacb4564ac3fe302ffeb23d7a 326 Gene3D G3DSA:3.40.190.10 48 163 5.2E-42 T 06-07-2017 SMD11_RS14895 3386490aacb4564ac3fe302ffeb23d7a 326 Gene3D G3DSA:3.40.190.120 164 261 4.2E-26 T 06-07-2017 SMD11_RS14895 3386490aacb4564ac3fe302ffeb23d7a 326 SUPERFAMILY SSF53850 51 323 1.67E-45 T 06-07-2017 SMD11_RS14895 3386490aacb4564ac3fe302ffeb23d7a 326 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 51 319 6.7E-52 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SMD11_RS26195 7d078f4cd97dfc4aab124cb21616205e 472 Gene3D G3DSA:3.40.605.10 6 257 3.4E-86 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS26195 7d078f4cd97dfc4aab124cb21616205e 472 Pfam PF00171 Aldehyde dehydrogenase family 13 469 3.0E-163 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SMD11_RS26195 7d078f4cd97dfc4aab124cb21616205e 472 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 SMD11_RS26195 7d078f4cd97dfc4aab124cb21616205e 472 Gene3D G3DSA:3.40.309.10 258 435 8.0E-63 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SMD11_RS26195 7d078f4cd97dfc4aab124cb21616205e 472 SUPERFAMILY SSF53720 6 470 9.42E-157 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SMD11_RS21165 e184a01da24637526d01b4efc04b55a3 136 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 3.1E-35 T 06-07-2017 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 SMD11_RS15680 df2e9eb91eca8f3e0325d64f21645184 194 Gene3D G3DSA:3.40.430.10 3 191 3.7E-29 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD11_RS15680 df2e9eb91eca8f3e0325d64f21645184 194 SUPERFAMILY SSF53597 2 191 3.4E-28 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SMD11_RS15680 df2e9eb91eca8f3e0325d64f21645184 194 Pfam PF01872 RibD C-terminal domain 2 185 7.8E-12 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SMD11_RS28820 b817c92675f5b7d80ccb9c7430191b74 257 Hamap MF_01385 Urease accessory protein UreF [ureF]. 35 257 19.768 T 06-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 SMD11_RS28820 b817c92675f5b7d80ccb9c7430191b74 257 Pfam PF01730 UreF 67 207 5.8E-21 T 06-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 SMD11_RS28820 b817c92675f5b7d80ccb9c7430191b74 257 PIRSF PIRSF009467 32 257 7.7E-49 T 06-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 SMD11_RS14345 1a975ac0ed5fd047cd61a265fdfb21a5 285 SUPERFAMILY SSF56059 113 254 3.53E-8 T 06-07-2017 SMD11_RS10315 a52218647c3740bb1329cb97adabbd01 112 Pfam PF03091 CutA1 divalent ion tolerance protein 8 104 2.2E-31 T 06-07-2017 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 SMD11_RS10315 a52218647c3740bb1329cb97adabbd01 112 SUPERFAMILY SSF54913 5 106 4.45E-32 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta SMD11_RS10315 a52218647c3740bb1329cb97adabbd01 112 Gene3D G3DSA:3.30.70.830 6 106 9.6E-35 T 06-07-2017 SMD11_RS11675 bd07d0a29ba1d21dce9582a0c254ad61 329 SUPERFAMILY SSF161098 105 310 2.01E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11675 bd07d0a29ba1d21dce9582a0c254ad61 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 326 6.8E-35 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS11675 bd07d0a29ba1d21dce9582a0c254ad61 329 Gene3D G3DSA:1.10.3720.10 103 321 5.6E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS09170 adab6c313bc1f76cd1afde12c6fb6d43 123 Gene3D G3DSA:1.10.287.1060 6 94 1.3E-8 T 06-07-2017 SMD11_RS09170 adab6c313bc1f76cd1afde12c6fb6d43 123 Pfam PF06013 Proteins of 100 residues with WXG 7 82 1.4E-7 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like SMD11_RS09170 adab6c313bc1f76cd1afde12c6fb6d43 123 SUPERFAMILY SSF140453 6 97 5.36E-12 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like SMD11_RS05950 f1a018ef9dff4850ca4a287397107182 78 Pfam PF11753 Protein of unknwon function (DUF3310) 7 68 3.0E-21 T 06-07-2017 IPR021739 Protein of unknwon function DUF3310 SMD11_RS16645 36a3a17c1f0320d2a26faca9181aa109 126 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 3 115 6.1E-30 T 06-07-2017 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV SMD11_RS12215 ca11977ee2683da02724106b7d61202e 82 Gene3D G3DSA:1.10.1220.10 15 58 1.6E-6 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SMD11_RS12215 ca11977ee2683da02724106b7d61202e 82 SUPERFAMILY SSF47598 13 63 7.23E-9 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 SMD11_RS13955 726f31c4c5f4ac2fdd604d7856176d92 310 SUPERFAMILY SSF53697 20 307 1.08E-41 T 06-07-2017 SMD11_RS13955 726f31c4c5f4ac2fdd604d7856176d92 310 Pfam PF01380 SIS domain 43 151 8.8E-6 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 SMD11_RS13955 726f31c4c5f4ac2fdd604d7856176d92 310 Gene3D G3DSA:3.40.50.10490 14 156 3.8E-16 T 06-07-2017 SMD11_RS13955 726f31c4c5f4ac2fdd604d7856176d92 310 Gene3D G3DSA:3.40.50.10490 174 306 1.2E-27 T 06-07-2017 SMD11_RS22405 5a5c7b521360b59e60466c5dff61995a 310 Pfam PF04085 rod shape-determining protein MreC 131 270 1.6E-33 T 06-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 SMD11_RS22405 5a5c7b521360b59e60466c5dff61995a 310 PIRSF PIRSF038471 2 282 2.2E-41 T 06-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 SMD11_RS01690 388f2789e43e30dcbe4ea9c0fb73fe7f 292 Pfam PF09234 Domain of unknown function (DUF1963) 55 291 6.6E-43 T 06-07-2017 IPR015315 Protein of unknown function DUF1963 SMD11_RS01690 388f2789e43e30dcbe4ea9c0fb73fe7f 292 SUPERFAMILY SSF103032 54 292 4.45E-34 T 06-07-2017 IPR015315 Protein of unknown function DUF1963 SMD11_RS01690 388f2789e43e30dcbe4ea9c0fb73fe7f 292 Gene3D G3DSA:2.30.320.10 22 292 3.6E-47 T 06-07-2017 IPR015315 Protein of unknown function DUF1963 SMD11_RS18680 d072e1d22629f69d09f14c59f77f0152 408 Pfam PF07730 Histidine kinase 216 280 8.1E-13 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS18680 d072e1d22629f69d09f14c59f77f0152 408 SUPERFAMILY SSF55874 303 402 1.22E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS18680 d072e1d22629f69d09f14c59f77f0152 408 Gene3D G3DSA:3.30.565.10 322 403 3.0E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS18680 d072e1d22629f69d09f14c59f77f0152 408 Pfam PF13796 Putative sensor 47 166 1.2E-28 T 06-07-2017 IPR025828 Putative sensor domain SMD11_RS00910 ab6ee26ca8371e9011e9544e0ddad0e7 69 SUPERFAMILY SSF51735 2 57 8.28E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS21980 a3c67c510e8357b1201d8b5f5a7fe463 262 Pfam PF01061 ABC-2 type transporter 14 226 8.9E-29 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD11_RS21980 a3c67c510e8357b1201d8b5f5a7fe463 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 111 136 3.8E-5 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS21980 a3c67c510e8357b1201d8b5f5a7fe463 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 204 223 3.8E-5 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS21980 a3c67c510e8357b1201d8b5f5a7fe463 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 30 51 3.8E-5 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS21980 a3c67c510e8357b1201d8b5f5a7fe463 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 184 203 3.8E-5 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS21980 a3c67c510e8357b1201d8b5f5a7fe463 262 PIRSF PIRSF006648 2 261 1.3E-65 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS25365 c27f8ae6f1b7e116f2b3e8c58e914187 241 Pfam PF02535 ZIP Zinc transporter 93 235 1.4E-12 T 06-07-2017 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 SMD11_RS30735 4f526f6c7f0ebe418dcdf0c93deb477d 141 Pfam PF03413 Peptidase propeptide and YPEB domain 78 133 4.0E-12 T 06-07-2017 IPR025711 PepSY domain SMD11_RS25540 015a489da513a342d86176800b4eaff1 128 Pfam PF11298 Protein of unknown function (DUF3099) 11 79 1.5E-22 T 06-07-2017 IPR021449 Protein of unknown function DUF3099 SMD11_RS15490 2a9d72b2f7a616357a0660d994099ddb 73 Gene3D G3DSA:1.10.10.10 9 56 7.5E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15490 2a9d72b2f7a616357a0660d994099ddb 73 SUPERFAMILY SSF46955 5 52 1.45E-6 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS15490 2a9d72b2f7a616357a0660d994099ddb 73 Pfam PF12728 Helix-turn-helix domain 5 49 4.2E-8 T 06-07-2017 SMD11_RS12465 9ac802855b02255a1146a783c9b3d21e 425 Gene3D G3DSA:3.40.50.1100 96 344 9.0E-78 T 06-07-2017 SMD11_RS12465 9ac802855b02255a1146a783c9b3d21e 425 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 43 328 1.7E-82 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS12465 9ac802855b02255a1146a783c9b3d21e 425 SUPERFAMILY SSF53686 30 378 9.04E-95 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SMD11_RS12465 9ac802855b02255a1146a783c9b3d21e 425 Gene3D G3DSA:3.30.70.260 350 400 3.5E-5 T 06-07-2017 SMD11_RS12465 9ac802855b02255a1146a783c9b3d21e 425 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 48 423 5.0E-132 T 06-07-2017 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 SMD11_RS33100 2b4527de2fb27c9e9a683f900bf328d2 235 Pfam PF14065 Protein of unknown function (DUF4255) 4 180 3.1E-42 T 06-07-2017 IPR025351 Protein of unknown function DUF4255 SMD11_RS31955 c3c3c51e177eeabbc7307eed3ef757b3 406 Gene3D G3DSA:3.50.50.60 271 348 2.0E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31955 c3c3c51e177eeabbc7307eed3ef757b3 406 Gene3D G3DSA:3.50.50.60 3 181 2.0E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31955 c3c3c51e177eeabbc7307eed3ef757b3 406 SUPERFAMILY SSF51905 5 176 1.04E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31955 c3c3c51e177eeabbc7307eed3ef757b3 406 SUPERFAMILY SSF51905 270 357 1.04E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS31955 c3c3c51e177eeabbc7307eed3ef757b3 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 2.5E-22 T 06-07-2017 SMD11_RS31955 c3c3c51e177eeabbc7307eed3ef757b3 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 2.5E-22 T 06-07-2017 SMD11_RS31955 c3c3c51e177eeabbc7307eed3ef757b3 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 2.5E-22 T 06-07-2017 SMD11_RS31955 c3c3c51e177eeabbc7307eed3ef757b3 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 2.5E-22 T 06-07-2017 SMD11_RS31955 c3c3c51e177eeabbc7307eed3ef757b3 406 Pfam PF01494 FAD binding domain 4 348 2.0E-58 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS32020 d4aad1fbc6f8b6e9125c09a6d234d7e4 362 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 15 259 1.6E-73 T 06-07-2017 IPR014145 DNA ligase D, polymerase domain SMD11_RS01640 b4f1a248588472ac946d6e9030821086 122 SUPERFAMILY SSF54593 1 119 8.75E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS01640 b4f1a248588472ac946d6e9030821086 122 PRINTS PR00311 Bleomycin resistance protein signature 37 48 1.4E-13 T 06-07-2017 IPR000335 Bleomycin resistance protein GO:0008144|GO:0046677 SMD11_RS01640 b4f1a248588472ac946d6e9030821086 122 PRINTS PR00311 Bleomycin resistance protein signature 25 36 1.4E-13 T 06-07-2017 IPR000335 Bleomycin resistance protein GO:0008144|GO:0046677 SMD11_RS01640 b4f1a248588472ac946d6e9030821086 122 PRINTS PR00311 Bleomycin resistance protein signature 6 23 1.4E-13 T 06-07-2017 IPR000335 Bleomycin resistance protein GO:0008144|GO:0046677 SMD11_RS01640 b4f1a248588472ac946d6e9030821086 122 Gene3D G3DSA:3.10.180.10 1 119 8.1E-36 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS23855 962eb5bf93e40034fc35bb95843ce5e5 490 PIRSF PIRSF006060 24 489 7.1E-46 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS23855 962eb5bf93e40034fc35bb95843ce5e5 490 Pfam PF13520 Amino acid permease 28 455 2.5E-48 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS13010 5710f84e0cdafca1547ecd849eef8517 66 Pfam PF04149 Domain of unknown function (DUF397) 6 58 2.8E-11 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS00475 e48be187346c0c66d3ed20c7c90054a9 260 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 36 146 9.7E-15 T 06-07-2017 SMD11_RS00475 e48be187346c0c66d3ed20c7c90054a9 260 SUPERFAMILY SSF53335 11 149 2.81E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS00475 e48be187346c0c66d3ed20c7c90054a9 260 Gene3D G3DSA:3.40.50.150 8 149 1.1E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29040 45c604543fb873136d1e13c43cda5f39 914 Pfam PF04738 Lantibiotic dehydratase, C terminus 135 859 1.1E-53 T 06-07-2017 IPR006827 Lantibiotic dehydratase, C-terminal SMD11_RS16460 6bf06fc5ec15ac213d1461aad7aa4d1d 197 SUPERFAMILY SSF144091 23 180 9.29E-5 T 06-07-2017 SMD11_RS07870 59b5cca34a3072b5f3c2fa4cfdc2abda 269 Pfam PF00701 Dihydrodipicolinate synthetase family 8 216 4.7E-29 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS07870 59b5cca34a3072b5f3c2fa4cfdc2abda 269 Gene3D G3DSA:3.20.20.70 5 218 6.0E-48 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS07870 59b5cca34a3072b5f3c2fa4cfdc2abda 269 SMART SM01130 6 264 1.2E-30 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS07870 59b5cca34a3072b5f3c2fa4cfdc2abda 269 SUPERFAMILY SSF51569 6 227 1.47E-42 T 06-07-2017 SMD11_RS07870 59b5cca34a3072b5f3c2fa4cfdc2abda 269 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 4.8E-8 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS07870 59b5cca34a3072b5f3c2fa4cfdc2abda 269 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 4.8E-8 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS07870 59b5cca34a3072b5f3c2fa4cfdc2abda 269 PRINTS PR00146 Dihydrodipicolinate synthase signature 106 122 4.8E-8 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS07870 59b5cca34a3072b5f3c2fa4cfdc2abda 269 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 4.8E-8 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 SMD11_RS30795 9b097eabc4888ff2109387cb2ba558e5 463 Gene3D G3DSA:3.90.1300.10 4 452 8.6E-149 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS30795 9b097eabc4888ff2109387cb2ba558e5 463 SUPERFAMILY SSF75304 3 451 4.58E-142 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS30795 9b097eabc4888ff2109387cb2ba558e5 463 Pfam PF01425 Amidase 24 444 2.8E-127 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SMD11_RS30795 9b097eabc4888ff2109387cb2ba558e5 463 ProSitePatterns PS00571 Amidases signature. 147 178 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SMD11_RS18700 ea572f804ac6692e0b349208df667650 321 Pfam PF00146 NADH dehydrogenase 11 313 3.6E-100 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS18700 ea572f804ac6692e0b349208df667650 321 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 3 320 22.33 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS12105 a4709a2e3062d3603305e0bb0c1c12b9 193 SUPERFAMILY SSF52980 18 163 3.16E-19 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD11_RS12105 a4709a2e3062d3603305e0bb0c1c12b9 193 Gene3D G3DSA:3.90.1570.10 9 161 1.8E-18 T 06-07-2017 IPR012296 Nuclease, putative, TT1808 SMD11_RS12105 a4709a2e3062d3603305e0bb0c1c12b9 193 Pfam PF05685 Putative restriction endonuclease 19 183 4.2E-27 T 06-07-2017 IPR008538 Domain of unknown function DUF820 SMD11_RS15955 913fbd995ab0b92dfeb7fc454af116cb 160 Pfam PF02082 Transcriptional regulator 1 83 9.1E-19 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type SMD11_RS15955 913fbd995ab0b92dfeb7fc454af116cb 160 Gene3D G3DSA:1.10.10.10 1 144 1.5E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15955 913fbd995ab0b92dfeb7fc454af116cb 160 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 138 2.9E-23 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type SMD11_RS15955 913fbd995ab0b92dfeb7fc454af116cb 160 SUPERFAMILY SSF46785 2 140 1.05E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS20395 35b03bdf4fd4d556c530b32cfc8af4c1 150 Gene3D G3DSA:3.90.1010.10 5 144 1.2E-41 T 06-07-2017 SMD11_RS20395 35b03bdf4fd4d556c530b32cfc8af4c1 150 Pfam PF01592 NifU-like N terminal domain 6 129 8.6E-26 T 06-07-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 SMD11_RS20395 35b03bdf4fd4d556c530b32cfc8af4c1 150 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 140 2.6E-45 T 06-07-2017 SMD11_RS20395 35b03bdf4fd4d556c530b32cfc8af4c1 150 SUPERFAMILY SSF82649 1 140 3.92E-42 T 06-07-2017 SMD11_RS31275 70a70885b2ab5a3bd7a57f69dc37a53a 253 SUPERFAMILY SSF53335 37 252 6.25E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS31275 70a70885b2ab5a3bd7a57f69dc37a53a 253 Gene3D G3DSA:3.40.50.150 51 252 1.3E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS31275 70a70885b2ab5a3bd7a57f69dc37a53a 253 Pfam PF08241 Methyltransferase domain 53 139 5.7E-8 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS04110 b54d5c2b45431ac40b3c6bbae46c8c98 286 SUPERFAMILY SSF53335 16 261 7.9E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS04110 b54d5c2b45431ac40b3c6bbae46c8c98 286 Gene3D G3DSA:3.40.50.150 14 257 2.2E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS04110 b54d5c2b45431ac40b3c6bbae46c8c98 286 Pfam PF13649 Methyltransferase domain 95 189 4.8E-11 T 06-07-2017 SMD11_RS08170 3dffbc5fb40f393d2ab2011f0e766f15 122 Gene3D G3DSA:3.10.450.50 4 119 7.8E-18 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS08170 3dffbc5fb40f393d2ab2011f0e766f15 122 Pfam PF12680 SnoaL-like domain 8 111 2.5E-14 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain SMD11_RS08170 3dffbc5fb40f393d2ab2011f0e766f15 122 SUPERFAMILY SSF54427 1 117 5.7E-35 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS00300 3194d5c7b1c5772870329b79c4aed9b2 193 Pfam PF01814 Hemerythrin HHE cation binding domain 16 127 3.6E-10 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 SMD11_RS27440 1a70cbeb8ac8a8fe03b61a4384579340 480 Pfam PF13520 Amino acid permease 25 431 5.5E-54 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS27440 1a70cbeb8ac8a8fe03b61a4384579340 480 PIRSF PIRSF006060 9 479 1.7E-90 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS06605 af8218ae3f8b697315ba03f4eef1a92d 169 Pfam PF12587 Protein of unknown function (DUF3761) 125 164 6.3E-14 T 06-07-2017 IPR022236 Protein of unknown function DUF3761 SMD11_RS07145 e7529ef25b24790e2944d375a3ccf1c6 375 Pfam PF13672 Protein phosphatase 2C 110 353 2.8E-20 T 06-07-2017 SMD11_RS18530 485f60eb2ccde80812d944c1430cf006 283 Pfam PF00877 NlpC/P60 family 181 271 1.1E-21 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS18530 485f60eb2ccde80812d944c1430cf006 283 SUPERFAMILY SSF54001 165 282 2.06E-36 T 06-07-2017 SMD11_RS18530 485f60eb2ccde80812d944c1430cf006 283 Gene3D G3DSA:3.90.1720.10 163 282 1.0E-36 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS23560 111fef79010fcfc606b611a28e617a7c 337 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 322 8.5E-127 T 06-07-2017 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c SMD11_RS23560 111fef79010fcfc606b611a28e617a7c 337 SUPERFAMILY SSF51679 1 329 5.59E-55 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS23560 111fef79010fcfc606b611a28e617a7c 337 Pfam PF00296 Luciferase-like monooxygenase 19 316 2.2E-59 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS23560 111fef79010fcfc606b611a28e617a7c 337 Gene3D G3DSA:3.20.20.30 1 334 2.3E-61 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS27965 87a8cc54bdffc69bd8a3f4e67bcd8b53 510 SUPERFAMILY SSF53474 360 442 1.05E-9 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS27965 87a8cc54bdffc69bd8a3f4e67bcd8b53 510 Gene3D G3DSA:3.40.50.1820 359 482 1.3E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS26115 f5f8665186ef2574ee74c0527eb761b2 459 SUPERFAMILY SSF51445 93 369 4.96E-33 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS26115 f5f8665186ef2574ee74c0527eb761b2 459 Gene3D G3DSA:3.20.20.80 98 366 2.8E-38 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS26695 3ec055b228eb84050d2839b8e434564a 268 Gene3D G3DSA:1.20.1080.10 16 235 3.0E-61 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMD11_RS26695 3ec055b228eb84050d2839b8e434564a 268 PRINTS PR00783 Major intrinsic protein family signature 146 164 1.7E-55 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26695 3ec055b228eb84050d2839b8e434564a 268 PRINTS PR00783 Major intrinsic protein family signature 215 235 1.7E-55 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26695 3ec055b228eb84050d2839b8e434564a 268 PRINTS PR00783 Major intrinsic protein family signature 17 36 1.7E-55 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26695 3ec055b228eb84050d2839b8e434564a 268 PRINTS PR00783 Major intrinsic protein family signature 90 109 1.7E-55 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26695 3ec055b228eb84050d2839b8e434564a 268 PRINTS PR00783 Major intrinsic protein family signature 53 77 1.7E-55 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26695 3ec055b228eb84050d2839b8e434564a 268 PRINTS PR00783 Major intrinsic protein family signature 176 198 1.7E-55 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26695 3ec055b228eb84050d2839b8e434564a 268 Pfam PF00230 Major intrinsic protein 16 232 3.9E-53 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26695 3ec055b228eb84050d2839b8e434564a 268 ProSitePatterns PS00221 MIP family signature. 71 79 - T 06-07-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26695 3ec055b228eb84050d2839b8e434564a 268 TIGRFAM TIGR00861 MIP: MIP family channel proteins 21 231 8.9E-53 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SMD11_RS26695 3ec055b228eb84050d2839b8e434564a 268 SUPERFAMILY SSF81338 17 236 8.63E-58 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SMD11_RS17080 a977829b4ee3b8e5186ab6362c940dfd 130 SMART SM00347 12 112 7.9E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS17080 a977829b4ee3b8e5186ab6362c940dfd 130 Pfam PF01047 MarR family 19 75 4.8E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS17080 a977829b4ee3b8e5186ab6362c940dfd 130 SUPERFAMILY SSF46785 15 127 5.54E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS17080 a977829b4ee3b8e5186ab6362c940dfd 130 Gene3D G3DSA:1.10.10.10 4 127 4.1E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS28165 84b5d41bb158f01738afd48f79a34549 329 Pfam PF05949 Bacterial protein of unknown function (DUF881) 192 324 1.4E-37 T 06-07-2017 IPR010273 Protein of unknown function DUF881 SMD11_RS19605 14d8ce2468ea3b134568db0fd66c53a5 267 Gene3D G3DSA:2.40.260.10 105 233 3.4E-4 T 06-07-2017 IPR023365 Sortase domain SMD11_RS19605 14d8ce2468ea3b134568db0fd66c53a5 267 Pfam PF04203 Sortase family 105 245 1.1E-14 T 06-07-2017 IPR005754 Sortase family SMD11_RS19605 14d8ce2468ea3b134568db0fd66c53a5 267 SUPERFAMILY SSF63817 101 246 1.49E-12 T 06-07-2017 IPR023365 Sortase domain SMD11_RS18715 a328ae63b7e3f8b244cad26282f5a358 119 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 97 8.8E-27 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 SMD11_RS18715 a328ae63b7e3f8b244cad26282f5a358 119 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 101 18.565 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 SMD11_RS09115 6a947abfc4a632f027f0211ad923549c 479 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 12 476 2.0E-50 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD SMD11_RS09115 6a947abfc4a632f027f0211ad923549c 479 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 9 83 1.3E-19 T 06-07-2017 IPR024962 YukD-like SMD11_RS09115 6a947abfc4a632f027f0211ad923549c 479 PIRSF PIRSF017804 1 479 3.6E-113 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD SMD11_RS13645 68db60fffa7632dba0c48f6f27762a84 1000 Pfam PF01565 FAD binding domain 40 177 8.7E-38 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SMD11_RS13645 68db60fffa7632dba0c48f6f27762a84 1000 Pfam PF13183 4Fe-4S dicluster domain 528 612 1.2E-9 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain SMD11_RS13645 68db60fffa7632dba0c48f6f27762a84 1000 Gene3D G3DSA:3.30.465.10 95 255 6.8E-34 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SMD11_RS13645 68db60fffa7632dba0c48f6f27762a84 1000 Pfam PF02754 Cysteine-rich domain 759 833 0.0027 T 06-07-2017 IPR004017 Cysteine-rich domain SMD11_RS13645 68db60fffa7632dba0c48f6f27762a84 1000 Pfam PF02913 FAD linked oxidases, C-terminal domain 255 489 3.5E-47 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 SMD11_RS13645 68db60fffa7632dba0c48f6f27762a84 1000 Gene3D G3DSA:3.30.43.10 8 93 1.8E-21 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SMD11_RS13645 68db60fffa7632dba0c48f6f27762a84 1000 SUPERFAMILY SSF56176 7 255 6.13E-58 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SMD11_RS13645 68db60fffa7632dba0c48f6f27762a84 1000 SUPERFAMILY SSF46548 529 617 2.82E-7 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 SMD11_RS13645 68db60fffa7632dba0c48f6f27762a84 1000 Gene3D G3DSA:1.10.1060.10 528 625 7.2E-10 T 06-07-2017 SMD11_RS13645 68db60fffa7632dba0c48f6f27762a84 1000 SUPERFAMILY SSF55103 258 502 1.24E-52 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 SMD11_RS09680 85be6ab3ad4542fb559993a2e051d12a 93 Pfam PF00708 Acylphosphatase 5 93 2.1E-21 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SMD11_RS09680 85be6ab3ad4542fb559993a2e051d12a 93 SUPERFAMILY SSF54975 4 93 1.02E-23 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SMD11_RS09680 85be6ab3ad4542fb559993a2e051d12a 93 Gene3D G3DSA:3.30.70.100 5 93 2.9E-26 T 06-07-2017 SMD11_RS09680 85be6ab3ad4542fb559993a2e051d12a 93 ProSitePatterns PS00150 Acylphosphatase signature 1. 11 21 - T 06-07-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SMD11_RS20510 45571881dd7d484d6a89eefbc7a3edd4 446 Pfam PF01979 Amidohydrolase family 53 419 1.7E-46 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 SMD11_RS20510 45571881dd7d484d6a89eefbc7a3edd4 446 SUPERFAMILY SSF51338 329 445 2.45E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SMD11_RS20510 45571881dd7d484d6a89eefbc7a3edd4 446 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 4 446 3.3E-166 T 06-07-2017 IPR010252 Formiminoglutamate deiminase SMD11_RS20510 45571881dd7d484d6a89eefbc7a3edd4 446 Gene3D G3DSA:3.20.20.140 57 388 3.1E-83 T 06-07-2017 SMD11_RS20510 45571881dd7d484d6a89eefbc7a3edd4 446 SUPERFAMILY SSF51556 54 371 8.24E-77 T 06-07-2017 IPR032466 Metal-dependent hydrolase SMD11_RS28485 76ec93bb5e034f59db13d390bd2486ff 1706 SUPERFAMILY SSF50974 1451 1673 3.14E-15 T 06-07-2017 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 SMD11_RS28485 76ec93bb5e034f59db13d390bd2486ff 1706 SUPERFAMILY SSF50974 1339 1404 3.14E-15 T 06-07-2017 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 SMD11_RS28485 76ec93bb5e034f59db13d390bd2486ff 1706 Gene3D G3DSA:2.130.10.10 1621 1672 8.1E-17 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS28485 76ec93bb5e034f59db13d390bd2486ff 1706 Gene3D G3DSA:2.130.10.10 1347 1529 8.1E-17 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS30620 053cba251749ff007fd0c60eedfbc166 524 Pfam PF00561 alpha/beta hydrolase fold 109 488 4.0E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS30620 053cba251749ff007fd0c60eedfbc166 524 Gene3D G3DSA:3.40.50.1820 75 155 4.8E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30620 053cba251749ff007fd0c60eedfbc166 524 Gene3D G3DSA:3.40.50.1820 378 500 4.8E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30620 053cba251749ff007fd0c60eedfbc166 524 Gene3D G3DSA:3.40.50.1820 198 319 4.8E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30620 053cba251749ff007fd0c60eedfbc166 524 SUPERFAMILY SSF53474 402 486 7.6E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30620 053cba251749ff007fd0c60eedfbc166 524 SUPERFAMILY SSF53474 200 254 7.6E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30620 053cba251749ff007fd0c60eedfbc166 524 SUPERFAMILY SSF53474 91 156 7.6E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15850 42e88d3b9323aad028dc9079437b5a23 415 SUPERFAMILY SSF56059 96 307 2.83E-35 T 06-07-2017 SMD11_RS15850 42e88d3b9323aad028dc9079437b5a23 415 Gene3D G3DSA:3.30.470.20 100 328 4.4E-28 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS15850 42e88d3b9323aad028dc9079437b5a23 415 SMART SM01209 103 273 0.0051 T 06-07-2017 SMD11_RS15850 42e88d3b9323aad028dc9079437b5a23 415 Pfam PF13535 ATP-grasp domain 140 274 1.3E-10 T 06-07-2017 SMD11_RS24015 3e313d07dbb7ffc1e4582e82d4da8d43 156 PIRSF PIRSF021697 3 155 6.1E-51 T 06-07-2017 IPR016795 Uncharacterised conserved protein UCP021697, membrane SMD11_RS24015 3e313d07dbb7ffc1e4582e82d4da8d43 156 Pfam PF06271 RDD family 42 148 3.9E-12 T 06-07-2017 IPR010432 RDD SMD11_RS08595 06f59dcb71dfafa393a27b14843eb2f8 267 SUPERFAMILY SSF54593 21 138 7.29E-13 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS08595 06f59dcb71dfafa393a27b14843eb2f8 267 SUPERFAMILY SSF54593 151 262 2.34E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS08595 06f59dcb71dfafa393a27b14843eb2f8 267 Gene3D G3DSA:3.10.180.10 21 137 1.4E-25 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS08595 06f59dcb71dfafa393a27b14843eb2f8 267 Gene3D G3DSA:3.10.180.10 150 262 1.0E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS09000 cd6e9833409d21e3a4748bbc1746dc99 216 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 26 195 3.3E-38 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 SMD11_RS09000 cd6e9833409d21e3a4748bbc1746dc99 216 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 74 96 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD11_RS09000 cd6e9833409d21e3a4748bbc1746dc99 216 Pfam PF01066 CDP-alcohol phosphatidyltransferase 26 96 6.1E-16 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SMD11_RS19475 034a20444b24940eeaf3ce67dccad9d3 538 PIRSF PIRSF006060 23 519 4.6E-49 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS19475 034a20444b24940eeaf3ce67dccad9d3 538 Pfam PF13520 Amino acid permease 50 448 7.7E-26 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS27640 02924f5694e41293e06413c50c9ca459 378 SUPERFAMILY SSF48452 162 356 3.08E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS27640 02924f5694e41293e06413c50c9ca459 378 Gene3D G3DSA:1.10.260.40 3 76 1.6E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS27640 02924f5694e41293e06413c50c9ca459 378 Gene3D G3DSA:1.25.40.10 202 357 7.2E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS28015 b4aabb287ae48554b8b792a5ca465884 230 Pfam PF06149 Protein of unknown function (DUF969) 1 217 8.2E-84 T 06-07-2017 IPR010374 Protein of unknown function DUF969 SMD11_RS18830 7c86bfe66e1a1866f012f2d28497761e 186 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 06-07-2017 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SMD11_RS18830 7c86bfe66e1a1866f012f2d28497761e 186 SUPERFAMILY SSF160369 1 168 2.75E-51 T 06-07-2017 SMD11_RS18830 7c86bfe66e1a1866f012f2d28497761e 186 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 25.066 T 06-07-2017 IPR022973 Ribosomal protein L10 SMD11_RS18830 7c86bfe66e1a1866f012f2d28497761e 186 Pfam PF00466 Ribosomal protein L10 2 98 3.3E-25 T 06-07-2017 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 SMD11_RS31145 7466bcacf1af9243fe89dba297f2d2c7 148 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 31 142 5.6E-38 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD11_RS31145 7466bcacf1af9243fe89dba297f2d2c7 148 SUPERFAMILY SSF50475 33 136 4.4E-6 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS31145 7466bcacf1af9243fe89dba297f2d2c7 148 Pfam PF04075 Domain of unknown function (DUF385) 14 143 5.1E-54 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 SMD11_RS31020 535c4e5c79d98ac93406196208f1e7d0 402 Gene3D G3DSA:3.40.50.1820 33 83 1.3E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS31020 535c4e5c79d98ac93406196208f1e7d0 402 Gene3D G3DSA:3.40.50.1820 210 401 1.3E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS31020 535c4e5c79d98ac93406196208f1e7d0 402 Gene3D G3DSA:3.40.50.1820 133 177 1.3E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS31020 535c4e5c79d98ac93406196208f1e7d0 402 SUPERFAMILY SSF53474 205 356 5.63E-16 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS31020 535c4e5c79d98ac93406196208f1e7d0 402 SUPERFAMILY SSF53474 130 169 5.63E-16 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12780 9cd30535dfda3de7f3cc818343160cdc 234 Pfam PF13581 Histidine kinase-like ATPase domain 59 162 1.2E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS13215 25b656edaa4557a5158439ae2f56ece5 211 Pfam PF06271 RDD family 55 204 6.1E-26 T 06-07-2017 IPR010432 RDD SMD11_RS13215 25b656edaa4557a5158439ae2f56ece5 211 SUPERFAMILY SSF81995 3 55 4.97E-7 T 06-07-2017 SMD11_RS04715 b07ce52f2dd7f673c3fe21e8a45c018c 374 Gene3D G3DSA:3.40.50.720 2 208 1.5E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04715 b07ce52f2dd7f673c3fe21e8a45c018c 374 Gene3D G3DSA:3.40.50.720 243 296 1.5E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04715 b07ce52f2dd7f673c3fe21e8a45c018c 374 SUPERFAMILY SSF51735 2 316 8.0E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS04715 b07ce52f2dd7f673c3fe21e8a45c018c 374 Pfam PF07993 Male sterility protein 6 265 2.0E-37 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 SMD11_RS27975 0228b77984e4545c52c4d81d4110a1d5 477 Gene3D G3DSA:1.10.630.10 47 439 8.5E-37 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27975 0228b77984e4545c52c4d81d4110a1d5 477 Pfam PF00067 Cytochrome P450 292 438 9.9E-21 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS27975 0228b77984e4545c52c4d81d4110a1d5 477 SUPERFAMILY SSF48264 53 442 1.01E-41 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS20330 4d6bd32a7123d4a4331ebba456084dd6 261 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SMD11_RS20330 4d6bd32a7123d4a4331ebba456084dd6 261 SMART SM00382 48 234 2.6E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS20330 4d6bd32a7123d4a4331ebba456084dd6 261 SUPERFAMILY SSF52540 22 238 4.8E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20330 4d6bd32a7123d4a4331ebba456084dd6 261 Gene3D G3DSA:3.40.50.300 23 239 1.5E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS20330 4d6bd32a7123d4a4331ebba456084dd6 261 Pfam PF00005 ABC transporter 39 185 1.6E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS14340 3a4bf33b094041c615a0a9c440a1abec 59 Pfam PF04149 Domain of unknown function (DUF397) 5 57 2.4E-10 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS02345 6ca8d956ffc2c65db87816ea0dbc5c9e 224 Pfam PF13761 Domain of unknown function (DUF4166) 16 201 4.6E-63 T 06-07-2017 IPR025311 Domain of unknown function DUF4166 SMD11_RS27375 f8d2fa419ea171ece67d29decd666946 291 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 93 106 - T 06-07-2017 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD11_RS27375 f8d2fa419ea171ece67d29decd666946 291 SUPERFAMILY SSF51366 6 275 4.38E-63 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SMD11_RS27375 f8d2fa419ea171ece67d29decd666946 291 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 19 270 2.2E-37 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD11_RS27375 f8d2fa419ea171ece67d29decd666946 291 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 6 270 9.0E-81 T 06-07-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 SMD11_RS27375 f8d2fa419ea171ece67d29decd666946 291 Gene3D G3DSA:3.20.20.70 8 276 3.3E-61 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 SMD11_RS27375 f8d2fa419ea171ece67d29decd666946 291 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 4 285 34.362 T 06-07-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 SMD11_RS27375 f8d2fa419ea171ece67d29decd666946 291 SMART SM00934 19 271 4.2E-26 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 SMD11_RS16410 9e897af25f1157c93d11b62825493114 159 Gene3D G3DSA:3.30.565.10 21 145 5.1E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16410 9e897af25f1157c93d11b62825493114 159 Pfam PF13581 Histidine kinase-like ATPase domain 12 144 5.1E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS16410 9e897af25f1157c93d11b62825493114 159 SUPERFAMILY SSF55874 31 137 5.89E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS33030 1b47b153360b854198e6e608578edc78 317 SUPERFAMILY SSF103481 43 134 1.44E-14 T 06-07-2017 SMD11_RS33030 1b47b153360b854198e6e608578edc78 317 Pfam PF00892 EamA-like transporter family 140 272 6.2E-21 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS33030 1b47b153360b854198e6e608578edc78 317 Pfam PF00892 EamA-like transporter family 2 130 2.4E-15 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 SMD11_RS33030 1b47b153360b854198e6e608578edc78 317 SUPERFAMILY SSF103481 174 272 3.4E-14 T 06-07-2017 SMD11_RS27715 c682d4f6e296bc8ec872ee952a150bc9 49 Pfam PF12728 Helix-turn-helix domain 2 39 3.0E-7 T 06-07-2017 SMD11_RS29230 d15c10c42ab29a13b9925e218e5ff994 319 Pfam PF03537 Glycoside-hydrolase family GH114 96 315 1.4E-81 T 06-07-2017 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain SMD11_RS29230 d15c10c42ab29a13b9925e218e5ff994 319 SUPERFAMILY SSF51445 89 319 3.79E-48 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS24840 34fbbf9413c8a2321eb56587d622961f 386 SUPERFAMILY SSF55874 268 380 2.71E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS24840 34fbbf9413c8a2321eb56587d622961f 386 Gene3D G3DSA:3.30.565.10 286 380 8.1E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS24840 34fbbf9413c8a2321eb56587d622961f 386 Pfam PF07730 Histidine kinase 179 243 3.0E-13 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SMD11_RS33795 c07136d1d9f8d2e5bb219386fe7b18fa 107 Gene3D G3DSA:3.30.1460.30 9 95 2.0E-4 T 06-07-2017 IPR007076 TfoX, N-terminal SMD11_RS33795 c07136d1d9f8d2e5bb219386fe7b18fa 107 SUPERFAMILY SSF159894 8 100 3.92E-9 T 06-07-2017 SMD11_RS33795 c07136d1d9f8d2e5bb219386fe7b18fa 107 Pfam PF04993 TfoX N-terminal domain 19 98 1.5E-10 T 06-07-2017 IPR007076 TfoX, N-terminal SMD11_RS19610 8bf0b5e30b8abcc6220292cf41c227bf 179 SMART SM00347 54 154 1.0E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS19610 8bf0b5e30b8abcc6220292cf41c227bf 179 SUPERFAMILY SSF46785 36 166 1.74E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19610 8bf0b5e30b8abcc6220292cf41c227bf 179 Gene3D G3DSA:1.10.10.10 40 166 6.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS19610 8bf0b5e30b8abcc6220292cf41c227bf 179 Pfam PF12802 MarR family 60 118 1.8E-11 T 06-07-2017 SMD11_RS15445 a620061e9cf7ce71739681c3e3e2b18c 306 Pfam PF05709 Phage tail protein 138 294 8.2E-12 T 06-07-2017 IPR008841 Siphovirus-type tail component SMD11_RS16890 f4a21729030992a93ecd7fdcf0afc8f1 105 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 3.0E-23 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor SMD11_RS16890 f4a21729030992a93ecd7fdcf0afc8f1 105 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 73 6.4E-26 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor SMD11_RS16890 f4a21729030992a93ecd7fdcf0afc8f1 105 SMART SM01234 1 68 3.5E-38 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor SMD11_RS16890 f4a21729030992a93ecd7fdcf0afc8f1 105 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 23.14 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor SMD11_RS16890 f4a21729030992a93ecd7fdcf0afc8f1 105 Pfam PF01809 Haemolytic domain 5 68 8.6E-27 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor SMD11_RS14900 8f94c5e1e34eeae8d9d6db7ebc34ca63 237 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 217 6.2E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS14900 8f94c5e1e34eeae8d9d6db7ebc34ca63 237 Gene3D G3DSA:1.10.3720.10 21 216 1.2E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS14900 8f94c5e1e34eeae8d9d6db7ebc34ca63 237 SUPERFAMILY SSF161098 21 203 8.24E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS10335 eb1b794c912494de3b974d9860ecd6b6 167 Pfam PF13581 Histidine kinase-like ATPase domain 48 154 5.9E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS10335 eb1b794c912494de3b974d9860ecd6b6 167 SUPERFAMILY SSF55874 74 154 7.03E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS07005 6945de41f6bc19c81220bc41538e64a9 281 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 250 262 5.7E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07005 6945de41f6bc19c81220bc41538e64a9 281 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 234 250 5.7E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07005 6945de41f6bc19c81220bc41538e64a9 281 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 220 234 5.7E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07005 6945de41f6bc19c81220bc41538e64a9 281 Gene3D G3DSA:1.10.10.10 212 279 6.8E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS07005 6945de41f6bc19c81220bc41538e64a9 281 SUPERFAMILY SSF55781 12 140 1.96E-11 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS07005 6945de41f6bc19c81220bc41538e64a9 281 Pfam PF01590 GAF domain 41 141 6.6E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 SMD11_RS07005 6945de41f6bc19c81220bc41538e64a9 281 Pfam PF00196 Bacterial regulatory proteins, luxR family 220 273 2.2E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07005 6945de41f6bc19c81220bc41538e64a9 281 SMART SM00421 217 274 7.0E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SMD11_RS07005 6945de41f6bc19c81220bc41538e64a9 281 SUPERFAMILY SSF46894 215 280 4.08E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SMD11_RS07005 6945de41f6bc19c81220bc41538e64a9 281 Gene3D G3DSA:3.30.450.40 17 115 3.3E-9 T 06-07-2017 IPR029016 GAF domain-like SMD11_RS23240 74f85e3670be4d34399a0eefe0d6f67c 286 Pfam PF09851 Short C-terminal domain 256 283 3.7E-8 T 06-07-2017 IPR018649 SHOCT domain SMD11_RS23240 74f85e3670be4d34399a0eefe0d6f67c 286 Pfam PF14472 Domain of unknown function (DUF4429) 139 228 1.2E-37 T 06-07-2017 IPR027860 Domain of unknown function DUF4429 SMD11_RS23240 74f85e3670be4d34399a0eefe0d6f67c 286 Pfam PF14472 Domain of unknown function (DUF4429) 12 106 1.3E-16 T 06-07-2017 IPR027860 Domain of unknown function DUF4429 SMD11_RS05945 3a5dae681be8582065865639a8208506 269 Gene3D G3DSA:3.60.21.10 3 179 1.9E-4 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like SMD11_RS25555 9ea748c46a08ed3d64530590c4a3e01d 463 SUPERFAMILY SSF111283 7 456 5.89E-65 T 06-07-2017 SMD11_RS25555 9ea748c46a08ed3d64530590c4a3e01d 463 Pfam PF01523 Putative modulator of DNA gyrase 23 325 9.6E-31 T 06-07-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 SMD11_RS13415 5d26672fe5e656c344197c9839670268 129 Gene3D G3DSA:2.60.120.10 4 109 6.4E-34 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS13415 5d26672fe5e656c344197c9839670268 129 SUPERFAMILY SSF51182 3 113 1.47E-22 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS13415 5d26672fe5e656c344197c9839670268 129 Pfam PF07883 Cupin domain 38 93 2.5E-11 T 06-07-2017 IPR013096 Cupin 2, conserved barrel SMD11_RS17415 6f2b9aeb04fb8a9b73405d90c0ab5ee1 172 Gene3D G3DSA:3.30.530.20 16 129 2.1E-18 T 06-07-2017 IPR023393 START-like domain SMD11_RS17415 6f2b9aeb04fb8a9b73405d90c0ab5ee1 172 SUPERFAMILY SSF55961 17 130 9.45E-19 T 06-07-2017 SMD11_RS17415 6f2b9aeb04fb8a9b73405d90c0ab5ee1 172 Pfam PF08982 Domain of unknown function (DUF1857) 17 127 8.7E-18 T 06-07-2017 IPR015075 Protein of unknown function DUF1857 SMD11_RS13460 e50da00c6d44903a76631b274b11ed1b 132 Pfam PF04134 Protein of unknown function, DUF393 7 114 6.5E-20 T 06-07-2017 IPR007263 Protein of unknown function DUF393 SMD11_RS23755 bcecc449c678a461729a652007d956a9 446 Pfam PF05977 Transmembrane secretion effector 36 429 1.8E-35 T 06-07-2017 IPR010290 Transmembrane secretion effector SMD11_RS23755 bcecc449c678a461729a652007d956a9 446 Gene3D G3DSA:1.20.1250.20 37 226 4.3E-20 T 06-07-2017 SMD11_RS23755 bcecc449c678a461729a652007d956a9 446 Gene3D G3DSA:1.20.1250.20 256 418 2.8E-15 T 06-07-2017 SMD11_RS23755 bcecc449c678a461729a652007d956a9 446 SUPERFAMILY SSF103473 38 422 5.49E-42 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS13365 5fad45cfdb86154da9e176e72a234bdf 597 SUPERFAMILY SSF51905 3 160 9.26E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13365 5fad45cfdb86154da9e176e72a234bdf 597 SUPERFAMILY SSF51905 196 316 9.26E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13365 5fad45cfdb86154da9e176e72a234bdf 597 SUPERFAMILY SSF51905 486 542 9.26E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13365 5fad45cfdb86154da9e176e72a234bdf 597 Pfam PF01266 FAD dependent oxidoreductase 7 295 3.7E-6 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SMD11_RS13365 5fad45cfdb86154da9e176e72a234bdf 597 Gene3D G3DSA:3.50.50.60 415 416 1.2E-81 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13365 5fad45cfdb86154da9e176e72a234bdf 597 Gene3D G3DSA:3.50.50.60 477 545 1.2E-81 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13365 5fad45cfdb86154da9e176e72a234bdf 597 Gene3D G3DSA:3.50.50.60 5 126 1.2E-81 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13365 5fad45cfdb86154da9e176e72a234bdf 597 Gene3D G3DSA:3.50.50.60 204 312 1.2E-81 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS13365 5fad45cfdb86154da9e176e72a234bdf 597 Pfam PF05199 GMC oxidoreductase 481 538 2.2E-13 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 SMD11_RS33915 43db13c6f5a72717a582a91607e26d1d 190 Pfam PF00583 Acetyltransferase (GNAT) family 66 141 3.9E-7 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS33915 43db13c6f5a72717a582a91607e26d1d 190 Gene3D G3DSA:3.40.630.30 56 189 7.2E-15 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS33915 43db13c6f5a72717a582a91607e26d1d 190 SUPERFAMILY SSF55729 46 189 4.46E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS12960 03878ea378ad4a06106ce39fdfb0aaef 131 Gene3D G3DSA:2.60.120.10 9 106 1.2E-17 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS12960 03878ea378ad4a06106ce39fdfb0aaef 131 SUPERFAMILY SSF51182 2 107 9.41E-20 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS12960 03878ea378ad4a06106ce39fdfb0aaef 131 Pfam PF07883 Cupin domain 37 106 2.7E-16 T 06-07-2017 IPR013096 Cupin 2, conserved barrel SMD11_RS24215 5c7ca9fe40b558296c0af9b44bd65985 206 Pfam PF00510 Cytochrome c oxidase subunit III 26 204 2.8E-24 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24215 5c7ca9fe40b558296c0af9b44bd65985 206 Gene3D G3DSA:1.20.120.80 25 205 1.0E-53 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS24215 5c7ca9fe40b558296c0af9b44bd65985 206 SUPERFAMILY SSF81452 12 205 3.14E-54 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS10940 7e72a75046a22adbdb0a5748debff0c3 385 Pfam PF00877 NlpC/P60 family 247 338 1.6E-18 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS10940 7e72a75046a22adbdb0a5748debff0c3 385 SUPERFAMILY SSF54001 232 346 8.83E-34 T 06-07-2017 SMD11_RS10940 7e72a75046a22adbdb0a5748debff0c3 385 Gene3D G3DSA:3.90.1720.10 232 346 1.5E-36 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS11845 3750195cfa82e6bcc61c680757eecf8e 260 Gene3D G3DSA:3.90.226.10 3 257 1.9E-75 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS11845 3750195cfa82e6bcc61c680757eecf8e 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 258 2.1E-57 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SMD11_RS11845 3750195cfa82e6bcc61c680757eecf8e 260 SUPERFAMILY SSF52096 2 259 6.89E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain SMD11_RS14330 51e2b7ebe0030f1e096919b661633b59 157 Pfam PF13581 Histidine kinase-like ATPase domain 17 122 1.5E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14330 51e2b7ebe0030f1e096919b661633b59 157 SUPERFAMILY SSF55874 45 123 4.88E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS14330 51e2b7ebe0030f1e096919b661633b59 157 Gene3D G3DSA:3.30.565.10 50 90 6.8E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS32650 9a6904e4b70a55561a466bb237647dbe 400 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 146 162 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site SMD11_RS32650 9a6904e4b70a55561a466bb237647dbe 400 SUPERFAMILY SSF53901 12 238 9.6E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32650 9a6904e4b70a55561a466bb237647dbe 400 SUPERFAMILY SSF53901 200 396 1.34E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32650 9a6904e4b70a55561a466bb237647dbe 400 Gene3D G3DSA:3.40.47.10 12 244 3.2E-50 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32650 9a6904e4b70a55561a466bb237647dbe 400 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 51 230 5.2E-37 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal SMD11_RS32650 9a6904e4b70a55561a466bb237647dbe 400 Gene3D G3DSA:3.40.47.10 250 396 3.7E-50 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS32650 9a6904e4b70a55561a466bb237647dbe 400 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 241 352 3.6E-32 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal SMD11_RS32650 9a6904e4b70a55561a466bb237647dbe 400 SMART SM00825 Beta-ketoacyl synthase 14 400 7.2E-14 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SMD11_RS17100 dd6ea36a3147c5879a1a907de1153cfb 115 Gene3D G3DSA:3.40.250.10 14 105 3.3E-24 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS17100 dd6ea36a3147c5879a1a907de1153cfb 115 Pfam PF00581 Rhodanese-like domain 17 99 4.7E-12 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS17100 dd6ea36a3147c5879a1a907de1153cfb 115 SUPERFAMILY SSF52821 16 107 6.42E-27 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS17100 dd6ea36a3147c5879a1a907de1153cfb 115 SMART SM00450 5 103 1.1E-15 T 06-07-2017 IPR001763 Rhodanese-like domain SMD11_RS25075 499942b53c8758caa00f872365640f04 144 SUPERFAMILY SSF50022 45 140 3.01E-28 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS25075 499942b53c8758caa00f872365640f04 144 Gene3D G3DSA:2.102.10.10 10 139 1.2E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS25075 499942b53c8758caa00f872365640f04 144 PRINTS PR00162 Rieske 2Fe-2S subunit signature 81 92 6.5E-10 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD11_RS25075 499942b53c8758caa00f872365640f04 144 PRINTS PR00162 Rieske 2Fe-2S subunit signature 114 126 6.5E-10 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD11_RS25075 499942b53c8758caa00f872365640f04 144 PRINTS PR00162 Rieske 2Fe-2S subunit signature 101 113 6.5E-10 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 SMD11_RS25075 499942b53c8758caa00f872365640f04 144 Pfam PF00355 Rieske [2Fe-2S] domain 50 129 2.9E-16 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 SMD11_RS17000 0cc94faebabdea6aecea2bcde6b68854 220 Pfam PF05949 Bacterial protein of unknown function (DUF881) 62 217 4.6E-41 T 06-07-2017 IPR010273 Protein of unknown function DUF881 SMD11_RS16295 ab5f2dec295ef1efb678ff714977fc4c 254 SMART SM00943 25 201 5.8E-23 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD11_RS16295 ab5f2dec295ef1efb678ff714977fc4c 254 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 25 198 1.0E-20 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD11_RS03130 1812a8ce7d8d506602b795a1c96734e3 281 SMART SM01134 80 253 3.6E-54 T 06-07-2017 SMD11_RS03130 1812a8ce7d8d506602b795a1c96734e3 281 SUPERFAMILY SSF100950 172 253 4.1E-28 T 06-07-2017 SMD11_RS03130 1812a8ce7d8d506602b795a1c96734e3 281 SUPERFAMILY SSF100950 84 139 4.1E-28 T 06-07-2017 SMD11_RS03130 1812a8ce7d8d506602b795a1c96734e3 281 SMART SM00420 12 64 1.0E-18 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS03130 1812a8ce7d8d506602b795a1c96734e3 281 Pfam PF08220 DeoR-like helix-turn-helix domain 12 65 2.0E-17 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS03130 1812a8ce7d8d506602b795a1c96734e3 281 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 30 44 9.2E-10 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS03130 1812a8ce7d8d506602b795a1c96734e3 281 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 44 62 9.2E-10 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SMD11_RS03130 1812a8ce7d8d506602b795a1c96734e3 281 ProSitePatterns PS00894 DeoR-type HTH domain signature. 12 46 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SMD11_RS03130 1812a8ce7d8d506602b795a1c96734e3 281 SUPERFAMILY SSF46785 10 67 4.94E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03130 1812a8ce7d8d506602b795a1c96734e3 281 Pfam PF00455 DeoR C terminal sensor domain 84 251 1.2E-47 T 06-07-2017 IPR014036 DeoR C-terminal sensor domain SMD11_RS03130 1812a8ce7d8d506602b795a1c96734e3 281 Gene3D G3DSA:1.10.10.10 11 87 1.0E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS03130 1812a8ce7d8d506602b795a1c96734e3 281 Gene3D G3DSA:3.40.50.1360 170 235 6.3E-14 T 06-07-2017 SMD11_RS03130 1812a8ce7d8d506602b795a1c96734e3 281 Gene3D G3DSA:3.40.50.1360 88 137 6.3E-14 T 06-07-2017 SMD11_RS24970 d2724ac25e7263dee4e4d68cfbd9f9f6 267 Pfam PF08241 Methyltransferase domain 74 166 1.3E-18 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS24970 d2724ac25e7263dee4e4d68cfbd9f9f6 267 Gene3D G3DSA:3.40.50.150 23 255 2.9E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS24970 d2724ac25e7263dee4e4d68cfbd9f9f6 267 SUPERFAMILY SSF53335 23 246 1.82E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS24815 d194ef601f63cae173da534e0e27f2da 353 Gene3D G3DSA:3.20.20.80 185 330 4.5E-6 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS24815 d194ef601f63cae173da534e0e27f2da 353 Gene3D G3DSA:3.20.20.140 3 125 8.8E-5 T 06-07-2017 SMD11_RS24815 d194ef601f63cae173da534e0e27f2da 353 SUPERFAMILY SSF51445 108 331 1.22E-22 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS25945 d9e59536d2aae3201bcdb6e4f5c7081f 338 SUPERFAMILY SSF48317 27 230 9.81E-27 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS25945 d9e59536d2aae3201bcdb6e4f5c7081f 338 SMART SM00014 104 219 2.1E-5 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS25945 d9e59536d2aae3201bcdb6e4f5c7081f 338 Pfam PF01569 PAP2 superfamily 106 220 8.7E-19 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS25945 d9e59536d2aae3201bcdb6e4f5c7081f 338 Gene3D G3DSA:1.20.144.10 74 221 7.9E-18 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SMD11_RS22685 8b54ba06dcac2a9c1832aede5fd8b5f4 139 SUPERFAMILY SSF55874 44 116 5.77E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS22685 8b54ba06dcac2a9c1832aede5fd8b5f4 139 Pfam PF13581 Histidine kinase-like ATPase domain 21 115 4.2E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS15540 28c119b3a4a32e92fcf30aad8823c90d 128 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 18 91 18.862 T 06-07-2017 IPR003482 Transcription factor WhiB SMD11_RS15540 28c119b3a4a32e92fcf30aad8823c90d 128 Pfam PF02467 Transcription factor WhiB 24 86 1.2E-24 T 06-07-2017 IPR003482 Transcription factor WhiB SMD11_RS19885 f0ba8dbde8156c263f4913f1214e2fb2 296 PRINTS PR00377 Inositol monophosphatase superfamily signature 209 230 3.9E-14 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS19885 f0ba8dbde8156c263f4913f1214e2fb2 296 PRINTS PR00377 Inositol monophosphatase superfamily signature 91 107 3.9E-14 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS19885 f0ba8dbde8156c263f4913f1214e2fb2 296 PRINTS PR00377 Inositol monophosphatase superfamily signature 160 183 3.9E-14 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS19885 f0ba8dbde8156c263f4913f1214e2fb2 296 PRINTS PR00377 Inositol monophosphatase superfamily signature 111 127 3.9E-14 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS19885 f0ba8dbde8156c263f4913f1214e2fb2 296 PRINTS PR00377 Inositol monophosphatase superfamily signature 240 264 3.9E-14 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS19885 f0ba8dbde8156c263f4913f1214e2fb2 296 Gene3D G3DSA:3.40.190.80 181 290 4.4E-22 T 06-07-2017 SMD11_RS19885 f0ba8dbde8156c263f4913f1214e2fb2 296 Pfam PF00459 Inositol monophosphatase family 32 291 1.6E-32 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 SMD11_RS19885 f0ba8dbde8156c263f4913f1214e2fb2 296 SUPERFAMILY SSF56655 25 291 8.25E-44 T 06-07-2017 SMD11_RS19885 f0ba8dbde8156c263f4913f1214e2fb2 296 Gene3D G3DSA:3.30.540.10 31 180 3.4E-27 T 06-07-2017 SMD11_RS32715 e43086ac0ee709bfbcbda91611b6f758 118 SUPERFAMILY SSF54593 7 112 2.06E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS32715 e43086ac0ee709bfbcbda91611b6f758 118 Gene3D G3DSA:3.10.180.10 5 110 7.6E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS32715 e43086ac0ee709bfbcbda91611b6f758 118 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 103 3.2E-5 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS30305 d022a0de88fafa1cc0c8e9862938467b 394 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 18 130 1.5E-10 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 SMD11_RS30305 d022a0de88fafa1cc0c8e9862938467b 394 SUPERFAMILY SSF52777 18 131 2.78E-7 T 06-07-2017 SMD11_RS32250 49c3bd5f01415d380199a8bcaebe00e3 144 Gene3D G3DSA:3.30.530.20 9 141 4.2E-6 T 06-07-2017 IPR023393 START-like domain SMD11_RS32250 49c3bd5f01415d380199a8bcaebe00e3 144 SUPERFAMILY SSF55961 10 141 1.88E-9 T 06-07-2017 SMD11_RS24280 e1689d723e478037fc9d750038c079ab 423 Pfam PF09594 Protein of unknown function (DUF2029) 62 309 1.4E-16 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 SMD11_RS24280 e1689d723e478037fc9d750038c079ab 423 PIRSF PIRSF010361 1 410 1.3E-80 T 06-07-2017 IPR016570 Uncharacterised conserved protein UCP010361, membrane SMD11_RS07380 168387a4cdbedeedc3fddaaaf54bce8b 430 SUPERFAMILY SSF88713 175 404 4.45E-22 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS07380 168387a4cdbedeedc3fddaaaf54bce8b 430 SUPERFAMILY SSF88713 104 145 4.45E-22 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SMD11_RS07380 168387a4cdbedeedc3fddaaaf54bce8b 430 Gene3D G3DSA:3.20.20.370 316 402 7.9E-9 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS07380 168387a4cdbedeedc3fddaaaf54bce8b 430 Gene3D G3DSA:3.20.20.370 89 274 7.9E-9 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 SMD11_RS31085 503170db3c232ab567619bd5f4d9f9dd 283 Pfam PF08241 Methyltransferase domain 75 173 1.6E-22 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS31085 503170db3c232ab567619bd5f4d9f9dd 283 Gene3D G3DSA:3.40.50.150 50 180 2.5E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS31085 503170db3c232ab567619bd5f4d9f9dd 283 Gene3D G3DSA:1.10.287.840 13 45 4.3E-26 T 06-07-2017 IPR023143 Mycolic acid cyclopropane synthase-like domain SMD11_RS31085 503170db3c232ab567619bd5f4d9f9dd 283 Gene3D G3DSA:1.10.287.840 181 274 4.3E-26 T 06-07-2017 IPR023143 Mycolic acid cyclopropane synthase-like domain SMD11_RS31085 503170db3c232ab567619bd5f4d9f9dd 283 SUPERFAMILY SSF53335 15 282 1.16E-56 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS13005 9f4e265cd46bd5038ea710055b31f427 283 SMART SM00530 17 72 5.9E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS13005 9f4e265cd46bd5038ea710055b31f427 283 Gene3D G3DSA:1.10.260.40 5 70 6.2E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS13005 9f4e265cd46bd5038ea710055b31f427 283 Pfam PF13560 Helix-turn-helix domain 13 71 2.1E-11 T 06-07-2017 SMD11_RS13005 9f4e265cd46bd5038ea710055b31f427 283 SUPERFAMILY SSF47413 10 69 7.78E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS10235 d8c34bf8eb3c40375a1e690a266d9d17 286 SUPERFAMILY SSF54637 142 282 3.58E-11 T 06-07-2017 IPR029069 HotDog domain SMD11_RS10235 d8c34bf8eb3c40375a1e690a266d9d17 286 Pfam PF13622 Thioesterase-like superfamily 40 282 2.5E-41 T 06-07-2017 SMD11_RS10235 d8c34bf8eb3c40375a1e690a266d9d17 286 SUPERFAMILY SSF54637 40 113 8.96E-6 T 06-07-2017 IPR029069 HotDog domain SMD11_RS23900 d26fe2dd0aac02239661b30a4c2b47bb 432 SUPERFAMILY SSF53850 42 424 8.89E-80 T 06-07-2017 SMD11_RS23900 d26fe2dd0aac02239661b30a4c2b47bb 432 Pfam PF01547 Bacterial extracellular solute-binding protein 54 344 4.0E-43 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 SMD11_RS23900 d26fe2dd0aac02239661b30a4c2b47bb 432 Gene3D G3DSA:3.40.190.10 53 172 6.0E-6 T 06-07-2017 SMD11_RS23900 d26fe2dd0aac02239661b30a4c2b47bb 432 Gene3D G3DSA:3.40.190.10 173 361 1.6E-46 T 06-07-2017 SMD11_RS06665 45ffdc66aaaa86c8c4cfb91b5a2cedcf 277 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 27 262 1.3E-30 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS06665 45ffdc66aaaa86c8c4cfb91b5a2cedcf 277 SUPERFAMILY SSF52266 24 274 6.0E-66 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS06665 45ffdc66aaaa86c8c4cfb91b5a2cedcf 277 Gene3D G3DSA:3.40.50.1110 20 274 7.6E-79 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS13335 9c85ccca099a0f9683f1d10d945daa50 341 Pfam PF03734 L,D-transpeptidase catalytic domain 180 303 3.1E-15 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMD11_RS13335 9c85ccca099a0f9683f1d10d945daa50 341 Gene3D G3DSA:2.40.440.10 181 304 2.1E-16 T 06-07-2017 SMD11_RS13335 9c85ccca099a0f9683f1d10d945daa50 341 SUPERFAMILY SSF141523 180 303 7.59E-22 T 06-07-2017 SMD11_RS05820 ebc318fc372347b22eac6264c3ccd9f0 177 Pfam PF03780 Asp23 family, cell envelope-related function 52 162 2.0E-33 T 06-07-2017 IPR005531 Alkaline shock protein Asp23 SMD11_RS23575 6c7c1ce1253cca5e8d0b1fc18c98ee01 212 Pfam PF13578 Methyltransferase domain 41 169 4.6E-22 T 06-07-2017 SMD11_RS23575 6c7c1ce1253cca5e8d0b1fc18c98ee01 212 Gene3D G3DSA:3.40.50.150 20 172 3.4E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS23575 6c7c1ce1253cca5e8d0b1fc18c98ee01 212 SUPERFAMILY SSF53335 40 196 3.49E-15 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS14530 b37220c060b4b0cd0c6d8d2f4d0d8d6a 113 Pfam PF10724 Protein of unknown function (DUF2516) 7 92 5.2E-28 T 06-07-2017 IPR019662 Protein of unknown function DUF2516 SMD11_RS23535 6a3c77174d666ec469e878691ab53748 452 Pfam PF00534 Glycosyl transferases group 1 258 414 3.5E-28 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 SMD11_RS23535 6a3c77174d666ec469e878691ab53748 452 Gene3D G3DSA:3.40.50.2000 227 414 6.2E-28 T 06-07-2017 SMD11_RS23535 6a3c77174d666ec469e878691ab53748 452 Pfam PF13439 Glycosyltransferase Family 4 42 244 4.0E-28 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 SMD11_RS23535 6a3c77174d666ec469e878691ab53748 452 SUPERFAMILY SSF53756 30 437 3.61E-79 T 06-07-2017 SMD11_RS21225 d20dc8ee874548c2e993c6981bcb811e 95 Pfam PF02597 ThiS family 5 93 1.3E-17 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 SMD11_RS21225 d20dc8ee874548c2e993c6981bcb811e 95 Gene3D G3DSA:3.10.20.30 3 91 1.0E-29 T 06-07-2017 IPR012675 Beta-grasp domain SMD11_RS21225 d20dc8ee874548c2e993c6981bcb811e 95 SUPERFAMILY SSF54285 1 93 1.18E-24 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp SMD11_RS31100 0be04c3d350f77a524a10451df962fc0 252 Pfam PF07510 Protein of unknown function (DUF1524) 92 229 5.7E-15 T 06-07-2017 IPR011089 Domain of unknown function DUF1524 SMD11_RS23365 750d2a6d6500d2732ad87e0a780ba7b3 159 Pfam PF07681 DoxX 37 116 8.6E-9 T 06-07-2017 IPR032808 DoxX family SMD11_RS20620 72ffe69905396351a4f1719d6158663c 182 Gene3D G3DSA:3.10.129.10 16 168 3.0E-54 T 06-07-2017 IPR029069 HotDog domain SMD11_RS20620 72ffe69905396351a4f1719d6158663c 182 Pfam PF03061 Thioesterase superfamily 37 107 6.4E-20 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 SMD11_RS20620 72ffe69905396351a4f1719d6158663c 182 SUPERFAMILY SSF54637 16 169 4.94E-44 T 06-07-2017 IPR029069 HotDog domain SMD11_RS11300 87d9686f9a1f3eb8de6aebb2a1ef4371 145 SUPERFAMILY SSF141066 45 116 9.16E-5 T 06-07-2017 IPR018990 Proteinase inhibitor I42, chagasin SMD11_RS08455 b0314cf93cf6e88a010293c3c3b2f324 370 Pfam PF13546 DDE superfamily endonuclease 1 244 1.8E-38 T 06-07-2017 SMD11_RS23490 f86983dbcead6a746b8e9986a22fba43 380 SUPERFAMILY SSF56281 28 371 2.88E-55 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS23490 f86983dbcead6a746b8e9986a22fba43 380 Gene3D G3DSA:3.60.15.10 30 332 7.1E-47 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS23490 f86983dbcead6a746b8e9986a22fba43 380 Pfam PF00753 Metallo-beta-lactamase superfamily 57 290 3.2E-16 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS23490 f86983dbcead6a746b8e9986a22fba43 380 SMART SM00849 57 290 2.2E-23 T 06-07-2017 IPR001279 Metallo-beta-lactamase SMD11_RS24140 51c9eaae4a4826cb93cfd9cd958de3a1 261 Pfam PF04012 PspA/IM30 family 2 227 2.1E-30 T 06-07-2017 IPR007157 PspA/IM30 SMD11_RS34015 34a299ec8c80e4124382a8620182834a 222 Pfam PF06736 Protein of unknown function (DUF1211) 15 106 2.8E-23 T 06-07-2017 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 SMD11_RS26745 61ba347eb7516b0f47baeceddd430149 445 Gene3D G3DSA:1.25.40.10 212 414 2.8E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS26745 61ba347eb7516b0f47baeceddd430149 445 SUPERFAMILY SSF48452 214 438 2.53E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS26025 2b1a085d9330b59d2b9b3b57eadbab75 330 Gene3D G3DSA:1.10.3720.10 106 324 1.2E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS26025 2b1a085d9330b59d2b9b3b57eadbab75 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 129 328 5.5E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS26025 2b1a085d9330b59d2b9b3b57eadbab75 330 SUPERFAMILY SSF161098 108 311 1.3E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS05530 82a70474ad58f1aa2cf02dae6e0c3209 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 2.6E-33 T 06-07-2017 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 SMD11_RS06580 e8b68e13532010f7a6b2c5ba5a133c06 219 SUPERFAMILY SSF81923 153 213 2.62E-5 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS06580 e8b68e13532010f7a6b2c5ba5a133c06 219 SUPERFAMILY SSF81923 3 67 9.29E-10 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS06580 e8b68e13532010f7a6b2c5ba5a133c06 219 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 165 212 0.0023 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS06580 e8b68e13532010f7a6b2c5ba5a133c06 219 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 64 2.9E-9 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS06580 e8b68e13532010f7a6b2c5ba5a133c06 219 Gene3D G3DSA:1.10.1780.10 141 215 7.6E-26 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS06580 e8b68e13532010f7a6b2c5ba5a133c06 219 Gene3D G3DSA:1.10.1780.10 77 99 7.6E-26 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS06580 e8b68e13532010f7a6b2c5ba5a133c06 219 Gene3D G3DSA:1.10.1780.10 1 45 7.6E-26 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 SMD11_RS24060 ca3356064446f818513154bdb8e416e1 354 SUPERFAMILY SSF51735 55 304 6.62E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS24060 ca3356064446f818513154bdb8e416e1 354 Pfam PF00106 short chain dehydrogenase 59 260 6.9E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS24060 ca3356064446f818513154bdb8e416e1 354 Gene3D G3DSA:3.40.50.720 54 305 1.2E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS24060 ca3356064446f818513154bdb8e416e1 354 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 243 8.4E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS24060 ca3356064446f818513154bdb8e416e1 354 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 212 8.4E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS24060 ca3356064446f818513154bdb8e416e1 354 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 60 77 8.4E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS24060 ca3356064446f818513154bdb8e416e1 354 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 155 8.4E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS24060 ca3356064446f818513154bdb8e416e1 354 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 245 262 8.4E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29035 b0f2fcf09ab57dda7ab4beb5370a72e1 352 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 17 347 1.4E-101 T 06-07-2017 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain SMD11_RS16500 73c18f0e51ca3f7528e0df4f93cfd502 282 Pfam PF00557 Metallopeptidase family M24 16 255 3.0E-29 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS16500 73c18f0e51ca3f7528e0df4f93cfd502 282 SUPERFAMILY SSF55920 13 166 8.37E-25 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS16500 73c18f0e51ca3f7528e0df4f93cfd502 282 SUPERFAMILY SSF55920 206 256 8.37E-25 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS16500 73c18f0e51ca3f7528e0df4f93cfd502 282 Gene3D G3DSA:3.90.230.10 14 255 1.2E-25 T 06-07-2017 IPR000994 Peptidase M24, structural domain SMD11_RS18390 b150711b7fef855d027cd5a8713cf6a5 578 Pfam PF05140 ResB-like family 71 549 1.0E-126 T 06-07-2017 IPR007816 ResB-like domain SMD11_RS31920 f87e7722884ef59343cc4d0da02d09e0 446 Gene3D G3DSA:1.10.630.10 52 408 1.7E-91 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS31920 f87e7722884ef59343cc4d0da02d09e0 446 Pfam PF00067 Cytochrome P450 221 391 3.1E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS31920 f87e7722884ef59343cc4d0da02d09e0 446 PRINTS PR00359 B-class P450 signature 214 236 1.4E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31920 f87e7722884ef59343cc4d0da02d09e0 446 PRINTS PR00359 B-class P450 signature 341 356 1.4E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31920 f87e7722884ef59343cc4d0da02d09e0 446 PRINTS PR00359 B-class P450 signature 362 371 1.4E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31920 f87e7722884ef59343cc4d0da02d09e0 446 PRINTS PR00359 B-class P450 signature 112 123 1.4E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31920 f87e7722884ef59343cc4d0da02d09e0 446 PRINTS PR00359 B-class P450 signature 159 175 1.4E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31920 f87e7722884ef59343cc4d0da02d09e0 446 PRINTS PR00359 B-class P450 signature 313 340 1.4E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31920 f87e7722884ef59343cc4d0da02d09e0 446 PRINTS PR00359 B-class P450 signature 176 191 1.4E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31920 f87e7722884ef59343cc4d0da02d09e0 446 PRINTS PR00359 B-class P450 signature 371 382 1.4E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31920 f87e7722884ef59343cc4d0da02d09e0 446 PRINTS PR00359 B-class P450 signature 295 306 1.4E-37 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 SMD11_RS31920 f87e7722884ef59343cc4d0da02d09e0 446 SUPERFAMILY SSF48264 54 406 4.19E-72 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 SMD11_RS16730 1169679b8e4609912971f48bf72f1d10 189 Pfam PF12840 Helix-turn-helix domain 23 71 1.5E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16730 1169679b8e4609912971f48bf72f1d10 189 SUPERFAMILY SSF46785 25 86 1.25E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS16730 1169679b8e4609912971f48bf72f1d10 189 Gene3D G3DSA:1.10.10.10 23 88 1.7E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS26205 4ef22b9f86a49cde609e05cc85f236b6 182 Pfam PF09933 Predicted small integral membrane protein (DUF2165) 16 171 6.0E-54 T 06-07-2017 IPR018681 Protein of unknown function DUF2165, transmembrane SMD11_RS26395 de329749b4b4dffe51af158eef00d6b1 480 Pfam PF07690 Major Facilitator Superfamily 34 433 1.2E-41 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS26395 de329749b4b4dffe51af158eef00d6b1 480 SUPERFAMILY SSF103473 270 475 1.03E-54 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS26395 de329749b4b4dffe51af158eef00d6b1 480 SUPERFAMILY SSF103473 22 216 1.03E-54 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS26395 de329749b4b4dffe51af158eef00d6b1 480 Gene3D G3DSA:1.20.1250.20 27 216 7.0E-24 T 06-07-2017 SMD11_RS26395 de329749b4b4dffe51af158eef00d6b1 480 Gene3D G3DSA:1.20.1250.20 284 471 2.1E-10 T 06-07-2017 SMD11_RS16995 395a099c53b7799061b4e683fb61c0a8 85 Pfam PF06781 Uncharacterised protein family (UPF0233) 2 85 7.1E-29 T 06-07-2017 IPR009619 Cell division protein CrgA SMD11_RS16995 395a099c53b7799061b4e683fb61c0a8 85 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 85 22.647 T 06-07-2017 IPR009619 Cell division protein CrgA SMD11_RS24900 7fe86a56675793bedf726fb873ea24b5 255 Gene3D G3DSA:1.10.10.60 6 39 6.8E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS09165 48d52cbe359a77f0e58f46077b7d4867 124 Pfam PF06013 Proteins of 100 residues with WXG 32 113 1.2E-9 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like SMD11_RS09165 48d52cbe359a77f0e58f46077b7d4867 124 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 32 117 1.9E-12 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like SMD11_RS09165 48d52cbe359a77f0e58f46077b7d4867 124 Gene3D G3DSA:1.10.287.1060 30 120 9.2E-15 T 06-07-2017 SMD11_RS09165 48d52cbe359a77f0e58f46077b7d4867 124 SUPERFAMILY SSF140453 29 120 1.7E-13 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like SMD11_RS21175 93e456c7bc8c26b46b585e3d1723b18b 247 Pfam PF06271 RDD family 106 239 3.5E-23 T 06-07-2017 IPR010432 RDD SMD11_RS15750 d86533dd4b3e3997372a5a64dfad46ce 265 SUPERFAMILY SSF54593 16 125 4.16E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS15750 d86533dd4b3e3997372a5a64dfad46ce 265 Gene3D G3DSA:3.10.180.10 138 254 8.7E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS15750 d86533dd4b3e3997372a5a64dfad46ce 265 Gene3D G3DSA:3.10.180.10 8 125 1.2E-30 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS15750 d86533dd4b3e3997372a5a64dfad46ce 265 SUPERFAMILY SSF54593 138 250 3.49E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS15750 d86533dd4b3e3997372a5a64dfad46ce 265 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 118 6.4E-6 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS18405 499642dbd0eb0cce2304015f3ea803e7 475 Pfam PF04185 Phosphoesterase family 47 402 4.1E-113 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 SMD11_RS08510 0d91ed316387de481f5021912ef9d42c 563 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 6 563 5.9E-201 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMD11_RS08510 0d91ed316387de481f5021912ef9d42c 563 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 563 32.374 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMD11_RS08510 0d91ed316387de481f5021912ef9d42c 563 Pfam PF03814 Potassium-transporting ATPase A subunit 14 562 6.5E-222 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMD11_RS08510 0d91ed316387de481f5021912ef9d42c 563 PIRSF PIRSF001294 4 563 9.7E-214 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 SMD11_RS21870 639e1c0d3d4b6b5fc9483204fc546706 305 SUPERFAMILY SSF51658 12 302 1.08E-47 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS21870 639e1c0d3d4b6b5fc9483204fc546706 305 Pfam PF01261 Xylose isomerase-like TIM barrel 39 241 8.0E-27 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS21870 639e1c0d3d4b6b5fc9483204fc546706 305 Gene3D G3DSA:3.20.20.150 10 303 1.8E-64 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain SMD11_RS17650 4ac676008b43fef07d88d80b361fada7 494 Pfam PF12697 Alpha/beta hydrolase family 5 235 3.4E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS17650 4ac676008b43fef07d88d80b361fada7 494 Gene3D G3DSA:3.40.50.1820 276 473 4.4E-19 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS17650 4ac676008b43fef07d88d80b361fada7 494 SUPERFAMILY SSF53474 277 470 3.3E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS17650 4ac676008b43fef07d88d80b361fada7 494 Gene3D G3DSA:3.40.50.1820 3 243 4.4E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS17650 4ac676008b43fef07d88d80b361fada7 494 SUPERFAMILY SSF53474 4 240 1.37E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32035 024fab41ab2e02f160639671a46d2335 173 Pfam PF10517 Electron transfer DM13 66 170 6.1E-28 T 06-07-2017 IPR019545 DM13 domain SMD11_RS25525 fd49b18ec91e881660a6e01a41aa24b1 548 Pfam PF00474 Sodium:solute symporter family 55 471 3.7E-93 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD11_RS30780 e2fda52ad608ab7dd6eb586998679c22 277 Pfam PF07398 MDMPI C-terminal domain 156 264 8.8E-10 T 06-07-2017 IPR010872 MDMPI C-terminal SMD11_RS30780 e2fda52ad608ab7dd6eb586998679c22 277 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 20 247 5.2E-27 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD11_RS30780 e2fda52ad608ab7dd6eb586998679c22 277 SUPERFAMILY SSF109854 19 149 3.43E-10 T 06-07-2017 SMD11_RS30780 e2fda52ad608ab7dd6eb586998679c22 277 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 20 144 4.2E-22 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD11_RS09710 5f2414fb2df6c349de132b1aea5cd60f 396 Gene3D G3DSA:1.20.5.620 62 115 3.9E-4 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain SMD11_RS32925 062a3c3e037c009a326cd41ad2bcceb5 416 SUPERFAMILY SSF56059 94 324 2.83E-29 T 06-07-2017 SMD11_RS32925 062a3c3e037c009a326cd41ad2bcceb5 416 SMART SM01209 109 290 0.0053 T 06-07-2017 SMD11_RS32925 062a3c3e037c009a326cd41ad2bcceb5 416 Gene3D G3DSA:3.30.470.20 102 314 9.6E-22 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SMD11_RS00335 2c7822f761221e67ca2e571959bb5ee1 390 Pfam PF00069 Protein kinase domain 17 256 8.5E-51 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS00335 2c7822f761221e67ca2e571959bb5ee1 390 Gene3D G3DSA:3.30.200.20 5 75 1.0E-21 T 06-07-2017 SMD11_RS00335 2c7822f761221e67ca2e571959bb5ee1 390 Gene3D G3DSA:1.10.510.10 76 257 4.5E-49 T 06-07-2017 SMD11_RS00335 2c7822f761221e67ca2e571959bb5ee1 390 SUPERFAMILY SSF56112 10 290 7.19E-72 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS00335 2c7822f761221e67ca2e571959bb5ee1 390 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 43 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 SMD11_RS00335 2c7822f761221e67ca2e571959bb5ee1 390 SMART SM00220 14 264 1.8E-63 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SMD11_RS03360 ed5d9d4bb6891871fc1c6bee4b7ace4a 153 Pfam PF13924 Lipocalin-like domain 17 151 5.3E-27 T 06-07-2017 IPR024311 Lipocalin-like domain SMD11_RS03315 7b41c66cbe22bb4f0fc33dc85b8e8ac7 327 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 10 147 6.7E-15 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase SMD11_RS03315 7b41c66cbe22bb4f0fc33dc85b8e8ac7 327 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 157 307 5.1E-7 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase SMD11_RS03315 7b41c66cbe22bb4f0fc33dc85b8e8ac7 327 SUPERFAMILY SSF55961 157 312 3.18E-21 T 06-07-2017 SMD11_RS03315 7b41c66cbe22bb4f0fc33dc85b8e8ac7 327 Gene3D G3DSA:3.30.530.20 10 146 1.8E-17 T 06-07-2017 IPR023393 START-like domain SMD11_RS03315 7b41c66cbe22bb4f0fc33dc85b8e8ac7 327 SUPERFAMILY SSF55961 8 147 3.85E-35 T 06-07-2017 SMD11_RS11285 fd4dd7bd06e3dcb2640ad2106c8be25b 423 Pfam PF01547 Bacterial extracellular solute-binding protein 50 336 1.4E-42 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 SMD11_RS11285 fd4dd7bd06e3dcb2640ad2106c8be25b 423 SUPERFAMILY SSF53850 19 421 6.8E-68 T 06-07-2017 SMD11_RS11285 fd4dd7bd06e3dcb2640ad2106c8be25b 423 Gene3D G3DSA:3.40.190.10 150 353 2.9E-35 T 06-07-2017 SMD11_RS07645 b2eb11a397a6875ebb7de4ea359671c2 305 SMART SM00943 13 194 6.8E-42 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD11_RS07645 b2eb11a397a6875ebb7de4ea359671c2 305 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 13 193 9.1E-40 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD11_RS07645 b2eb11a397a6875ebb7de4ea359671c2 305 SUPERFAMILY SSF56747 12 201 7.19E-23 T 06-07-2017 SMD11_RS09320 7f6d2eacb5fced7f4b1fc11c8a2825a2 552 Pfam PF07905 Purine catabolism regulatory protein-like family 9 126 1.5E-33 T 06-07-2017 IPR012914 Purine catabolism PurC-like domain SMD11_RS09320 7f6d2eacb5fced7f4b1fc11c8a2825a2 552 Pfam PF13556 PucR C-terminal helix-turn-helix domain 488 545 1.7E-22 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain SMD11_RS06085 e5bb6ef5052e0dfc754284f67bae10cf 499 Pfam PF14594 Siphovirus ReqiPepy6 Gp37-like protein 376 467 7.4E-11 T 06-07-2017 IPR029432 Siphovirus Gp37-like protein SMD11_RS06085 e5bb6ef5052e0dfc754284f67bae10cf 499 Pfam PF14594 Siphovirus ReqiPepy6 Gp37-like protein 17 296 4.0E-46 T 06-07-2017 IPR029432 Siphovirus Gp37-like protein SMD11_RS04495 0b112b7edf6901f32453791d6683576e 255 Pfam PF09490 Probable cobalt transporter subunit (CbtA) 7 230 2.4E-67 T 06-07-2017 IPR012666 Cobalt transporter subunit CbtA, putative SMD11_RS26640 4c670daeda597cd5df5971937eb3dc45 235 Gene3D G3DSA:3.40.50.880 4 218 1.5E-43 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS26640 4c670daeda597cd5df5971937eb3dc45 235 Pfam PF07722 Peptidase C26 5 217 4.6E-62 T 06-07-2017 IPR011697 Peptidase C26 GO:0006541|GO:0016787 SMD11_RS26640 4c670daeda597cd5df5971937eb3dc45 235 SUPERFAMILY SSF52317 32 232 5.5E-37 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like SMD11_RS12745 f610e1cf34037ea4d4263e411f617cbf 259 Gene3D G3DSA:3.40.50.1820 34 220 4.6E-18 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12745 f610e1cf34037ea4d4263e411f617cbf 259 SUPERFAMILY SSF53474 39 221 1.68E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS26475 c435e017199891e6868cc0ef1e6f2633 335 Pfam PF12705 PD-(D/E)XK nuclease superfamily 61 315 1.3E-38 T 06-07-2017 SMD11_RS26475 c435e017199891e6868cc0ef1e6f2633 335 SUPERFAMILY SSF52980 85 259 2.14E-10 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SMD11_RS03625 4bdfef16e3bbbad2d97b0e91032f2631 297 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 42 247 1.3E-22 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 SMD11_RS01285 d499b9ac6ddfee9cfd32829bbe9f0173 320 SUPERFAMILY SSF81345 4 317 1.83E-72 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS01285 d499b9ac6ddfee9cfd32829bbe9f0173 320 Gene3D G3DSA:1.10.3470.10 3 318 6.8E-94 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS01285 d499b9ac6ddfee9cfd32829bbe9f0173 320 Pfam PF01032 FecCD transport family 8 317 1.2E-89 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD11_RS30405 273294fe7dac772e3e0b54f33a89f84f 235 Gene3D G3DSA:3.40.630.30 106 229 3.7E-9 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS30405 273294fe7dac772e3e0b54f33a89f84f 235 SUPERFAMILY SSF55729 105 233 1.1E-13 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS17685 ba5ec94844080142456696922470ea54 178 Pfam PF10722 Putative bacterial sensory transduction regulator 30 156 5.4E-17 T 06-07-2017 IPR019660 Putative sensory transduction regulator YbjN SMD11_RS27200 4c68acf821c92ab64785c0404151453c 605 Pfam PF02355 Protein export membrane protein 391 566 2.1E-12 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial SMD11_RS27200 4c68acf821c92ab64785c0404151453c 605 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 315 553 8.6E-65 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial SMD11_RS27200 4c68acf821c92ab64785c0404151453c 605 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 45 561 7.5E-105 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 SMD11_RS27200 4c68acf821c92ab64785c0404151453c 605 Gene3D G3DSA:1.20.1640.10 367 569 3.1E-22 T 06-07-2017 SMD11_RS27200 4c68acf821c92ab64785c0404151453c 605 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 9 575 39.483 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 SMD11_RS27200 4c68acf821c92ab64785c0404151453c 605 SUPERFAMILY SSF82866 367 568 8.63E-38 T 06-07-2017 SMD11_RS04515 cdedef1ded1abd972a98b3fba4c0227a 737 SUPERFAMILY SSF81345 32 355 1.31E-65 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS04515 cdedef1ded1abd972a98b3fba4c0227a 737 Pfam PF01032 FecCD transport family 43 355 1.7E-79 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD11_RS04515 cdedef1ded1abd972a98b3fba4c0227a 737 Pfam PF01032 FecCD transport family 425 729 1.5E-71 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD11_RS04515 cdedef1ded1abd972a98b3fba4c0227a 737 Gene3D G3DSA:1.10.3470.10 413 732 3.6E-73 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS04515 cdedef1ded1abd972a98b3fba4c0227a 737 Gene3D G3DSA:1.10.3470.10 34 358 5.1E-84 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS04515 cdedef1ded1abd972a98b3fba4c0227a 737 SUPERFAMILY SSF81345 409 729 1.06E-59 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS13735 8873a3cce93b2740708d2766c37d8a0a 145 Gene3D G3DSA:3.10.180.10 11 127 2.0E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS13735 8873a3cce93b2740708d2766c37d8a0a 145 SUPERFAMILY SSF54593 10 125 3.89E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS13735 8873a3cce93b2740708d2766c37d8a0a 145 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 117 1.2E-9 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS28175 6ec21b38a4e6380e3da82368e626d1fc 261 SMART SM00422 22 96 1.6E-14 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS28175 6ec21b38a4e6380e3da82368e626d1fc 261 Gene3D G3DSA:1.10.1660.10 37 102 2.9E-17 T 06-07-2017 SMD11_RS28175 6ec21b38a4e6380e3da82368e626d1fc 261 Pfam PF00376 MerR family regulatory protein 23 64 4.1E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SMD11_RS28175 6ec21b38a4e6380e3da82368e626d1fc 261 SUPERFAMILY SSF46955 37 101 2.01E-12 T 06-07-2017 IPR009061 Putative DNA-binding domain SMD11_RS21600 d4a71899e3ba186355a107810d274a6f 288 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 214 1.3E-20 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 SMD11_RS05970 ec9ee0dc57f4264cc8b2a3baccda1091 274 Pfam PF13481 AAA domain 30 193 2.9E-10 T 06-07-2017 SMD11_RS05970 ec9ee0dc57f4264cc8b2a3baccda1091 274 SUPERFAMILY SSF52540 124 245 3.45E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05970 ec9ee0dc57f4264cc8b2a3baccda1091 274 SUPERFAMILY SSF52540 17 82 3.45E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS05970 ec9ee0dc57f4264cc8b2a3baccda1091 274 Gene3D G3DSA:3.40.50.300 17 193 4.3E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS09355 c0509073042d36038320808d78e01c1d 305 SUPERFAMILY SSF161098 21 298 2.22E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS09355 c0509073042d36038320808d78e01c1d 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 293 2.7E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS09355 c0509073042d36038320808d78e01c1d 305 Gene3D G3DSA:1.10.3720.10 20 295 1.4E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS06015 0c32bcccc12905e540654b2159d88cca 472 Pfam PF03354 Phage Terminase 67 328 1.3E-9 T 06-07-2017 IPR005021 Phage terminase SMD11_RS30215 d0ed9fc315ee2fb69f8a349af8f7bf49 258 Gene3D G3DSA:3.40.50.1820 4 256 9.6E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30215 d0ed9fc315ee2fb69f8a349af8f7bf49 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 101 3.8E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS30215 d0ed9fc315ee2fb69f8a349af8f7bf49 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 3.8E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS30215 d0ed9fc315ee2fb69f8a349af8f7bf49 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 3.8E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS30215 d0ed9fc315ee2fb69f8a349af8f7bf49 258 Pfam PF12697 Alpha/beta hydrolase family 25 247 1.0E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS30215 d0ed9fc315ee2fb69f8a349af8f7bf49 258 SUPERFAMILY SSF53474 4 255 2.77E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12895 e6300458f5561b896fc4fb17f27967e6 465 PIRSF PIRSF002746 20 465 6.2E-140 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMD11_RS12895 e6300458f5561b896fc4fb17f27967e6 465 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 27 465 4.4E-135 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMD11_RS12895 e6300458f5561b896fc4fb17f27967e6 465 Pfam PF02447 GntP family permease 27 464 7.8E-139 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 SMD11_RS00070 e0dbd2cea47a65490b4eb357a42e1482 224 Gene3D G3DSA:3.40.50.300 156 216 2.9E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS00070 e0dbd2cea47a65490b4eb357a42e1482 224 SUPERFAMILY SSF52540 151 216 5.97E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS24890 7de7294e639db414ab0ebf3e6e4484dd 245 Pfam PF04402 Protein of unknown function (DUF541) 29 237 8.4E-33 T 06-07-2017 IPR007497 Protein of unknown function DUF541 SMD11_RS29695 b35ebc31265752226cf912492d69c33d 148 Gene3D G3DSA:3.10.580.10 8 129 3.5E-27 T 06-07-2017 SMD11_RS29695 b35ebc31265752226cf912492d69c33d 148 SUPERFAMILY SSF54631 6 139 2.53E-27 T 06-07-2017 SMD11_RS29695 b35ebc31265752226cf912492d69c33d 148 Pfam PF00571 CBS domain 9 61 5.3E-9 T 06-07-2017 IPR000644 CBS domain SMD11_RS29695 b35ebc31265752226cf912492d69c33d 148 Pfam PF00571 CBS domain 84 131 7.3E-8 T 06-07-2017 IPR000644 CBS domain SMD11_RS29695 b35ebc31265752226cf912492d69c33d 148 SMART SM00116 82 132 2.3E-5 T 06-07-2017 IPR000644 CBS domain SMD11_RS29695 b35ebc31265752226cf912492d69c33d 148 SMART SM00116 17 65 8.2E-6 T 06-07-2017 IPR000644 CBS domain SMD11_RS21025 6a3316360891f4980c8bbf5e55e31966 100 Pfam PF11238 Protein of unknown function (DUF3039) 26 81 1.2E-31 T 06-07-2017 IPR021400 Protein of unknown function DUF3039 SMD11_RS19660 d8a05abb701f47b8137ea3442cf13097 432 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 81 343 2.2E-43 T 06-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMD11_RS19660 d8a05abb701f47b8137ea3442cf13097 432 Gene3D G3DSA:3.40.390.10 203 280 9.0E-6 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD11_RS10005 f4d4dff470a828376ec96b0afebf9fc3 410 Pfam PF13556 PucR C-terminal helix-turn-helix domain 349 407 2.6E-21 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain SMD11_RS10005 f4d4dff470a828376ec96b0afebf9fc3 410 Gene3D G3DSA:1.10.10.60 344 384 3.5E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS28105 774218fa711d90d4f3e48c031a3f2ba4 419 Gene3D G3DSA:1.20.1250.20 218 395 1.6E-7 T 06-07-2017 SMD11_RS28105 774218fa711d90d4f3e48c031a3f2ba4 419 Gene3D G3DSA:1.20.1250.20 2 178 5.5E-16 T 06-07-2017 SMD11_RS28105 774218fa711d90d4f3e48c031a3f2ba4 419 Pfam PF07690 Major Facilitator Superfamily 16 369 2.9E-14 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS28105 774218fa711d90d4f3e48c031a3f2ba4 419 SUPERFAMILY SSF103473 2 395 2.75E-28 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS15845 a16b15d9eea63fe4fc3639e7f01218bc 408 Gene3D G3DSA:1.20.1250.20 11 200 2.1E-17 T 06-07-2017 SMD11_RS15845 a16b15d9eea63fe4fc3639e7f01218bc 408 SUPERFAMILY SSF103473 12 400 7.32E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS15845 a16b15d9eea63fe4fc3639e7f01218bc 408 Gene3D G3DSA:1.20.1250.20 230 397 2.0E-11 T 06-07-2017 SMD11_RS15845 a16b15d9eea63fe4fc3639e7f01218bc 408 Pfam PF05977 Transmembrane secretion effector 8 404 3.9E-28 T 06-07-2017 IPR010290 Transmembrane secretion effector SMD11_RS25295 aa1b3bed563be9a08d06b4163c44b5e6 278 Gene3D G3DSA:3.40.50.720 4 209 8.3E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS25295 aa1b3bed563be9a08d06b4163c44b5e6 278 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 165 1.4E-19 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 SMD11_RS25295 aa1b3bed563be9a08d06b4163c44b5e6 278 SUPERFAMILY SSF51735 1 231 3.21E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS20535 a37e3e91333cacb68c0acff9098e86a8 122 Pfam PF13466 STAS domain 30 105 3.2E-17 T 06-07-2017 IPR002645 STAS domain SMD11_RS20535 a37e3e91333cacb68c0acff9098e86a8 122 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 14 117 1.7E-25 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 SMD11_RS20535 a37e3e91333cacb68c0acff9098e86a8 122 Gene3D G3DSA:3.30.750.24 14 121 4.6E-36 T 06-07-2017 IPR002645 STAS domain SMD11_RS20535 a37e3e91333cacb68c0acff9098e86a8 122 SUPERFAMILY SSF52091 14 121 4.12E-27 T 06-07-2017 IPR002645 STAS domain SMD11_RS12300 3ea262106b87a13d9d93816b7c3c4687 211 Gene3D G3DSA:3.30.1330.60 96 207 2.2E-27 T 06-07-2017 IPR006665 OmpA-like domain SMD11_RS12300 3ea262106b87a13d9d93816b7c3c4687 211 PRINTS PR01021 OMPA domain signature 106 128 7.3E-7 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SMD11_RS12300 3ea262106b87a13d9d93816b7c3c4687 211 PRINTS PR01021 OMPA domain signature 151 167 7.3E-7 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SMD11_RS12300 3ea262106b87a13d9d93816b7c3c4687 211 PRINTS PR01021 OMPA domain signature 136 151 7.3E-7 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 SMD11_RS12300 3ea262106b87a13d9d93816b7c3c4687 211 SUPERFAMILY SSF103088 96 207 1.16E-27 T 06-07-2017 IPR006665 OmpA-like domain SMD11_RS12300 3ea262106b87a13d9d93816b7c3c4687 211 Pfam PF00691 OmpA family 105 201 4.4E-13 T 06-07-2017 IPR006665 OmpA-like domain SMD11_RS14915 088b575ec0f342dbf28c0400e4dfa5de 164 Pfam PF11377 Protein of unknown function (DUF3180) 9 150 1.9E-35 T 06-07-2017 IPR021517 Protein of unknown function DUF3180 SMD11_RS01280 ba983621c07b6d0188793240438eea93 348 SUPERFAMILY SSF81345 15 337 2.88E-65 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS01280 ba983621c07b6d0188793240438eea93 348 Pfam PF01032 FecCD transport family 30 337 2.8E-74 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD11_RS01280 ba983621c07b6d0188793240438eea93 348 Gene3D G3DSA:1.10.3470.10 16 340 3.1E-82 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS32595 4fcb982ea4c4df932316e714d39fc8ad 185 Pfam PF02632 BioY family 31 177 1.8E-35 T 06-07-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 SMD11_RS32595 4fcb982ea4c4df932316e714d39fc8ad 185 PIRSF PIRSF016661 1 185 1.3E-43 T 06-07-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 SMD11_RS09090 d78144c75505c91a0326d0c83cab0bd5 153 SUPERFAMILY SSF48452 51 144 4.74E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS09090 d78144c75505c91a0326d0c83cab0bd5 153 Gene3D G3DSA:1.25.40.10 109 144 3.9E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS12040 875b86b8a27b179dbae0ef25e50a4aee 602 Gene3D G3DSA:3.10.105.10 338 573 6.7E-59 T 06-07-2017 SMD11_RS12040 875b86b8a27b179dbae0ef25e50a4aee 602 Gene3D G3DSA:3.90.76.10 95 189 4.5E-9 T 06-07-2017 SMD11_RS12040 875b86b8a27b179dbae0ef25e50a4aee 602 PIRSF PIRSF002741 20 590 6.4E-47 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SMD11_RS12040 875b86b8a27b179dbae0ef25e50a4aee 602 Gene3D G3DSA:3.40.190.10 190 337 1.9E-19 T 06-07-2017 SMD11_RS12040 875b86b8a27b179dbae0ef25e50a4aee 602 SUPERFAMILY SSF53850 57 598 5.43E-75 T 06-07-2017 SMD11_RS12040 875b86b8a27b179dbae0ef25e50a4aee 602 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 121 503 2.3E-46 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain SMD11_RS01360 ac32663a27572f589acc8cc1956d3616 106 Gene3D G3DSA:1.10.1510.10 1 100 5.7E-11 T 06-07-2017 SMD11_RS06750 ae5cc6dda9884d8470c535e025a05408 613 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 409 602 8.2E-24 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS06750 ae5cc6dda9884d8470c535e025a05408 613 SUPERFAMILY SSF52266 403 608 6.11E-42 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS06750 ae5cc6dda9884d8470c535e025a05408 613 Gene3D G3DSA:3.40.50.1110 406 608 1.1E-29 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS11770 6578a31031ab88414e71472333d8391c 368 Pfam PF01544 CorA-like Mg2+ transporter protein 66 358 3.6E-64 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SMD11_RS11770 6578a31031ab88414e71472333d8391c 368 Gene3D G3DSA:3.30.460.20 24 173 2.7E-47 T 06-07-2017 SMD11_RS11770 6578a31031ab88414e71472333d8391c 368 Gene3D G3DSA:1.20.58.340 174 290 4.6E-39 T 06-07-2017 SMD11_RS11770 6578a31031ab88414e71472333d8391c 368 SUPERFAMILY SSF144083 304 365 1.1E-20 T 06-07-2017 SMD11_RS11770 6578a31031ab88414e71472333d8391c 368 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 66 368 7.9E-60 T 06-07-2017 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 SMD11_RS11770 6578a31031ab88414e71472333d8391c 368 SUPERFAMILY SSF143865 30 301 1.96E-65 T 06-07-2017 SMD11_RS11770 6578a31031ab88414e71472333d8391c 368 Gene3D G3DSA:1.20.58.340 292 368 5.8E-28 T 06-07-2017 SMD11_RS33715 b2c946937483a222a12e8483a0476daf 302 Pfam PF00248 Aldo/keto reductase family 14 295 5.1E-61 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS33715 b2c946937483a222a12e8483a0476daf 302 Gene3D G3DSA:3.20.20.100 4 295 3.5E-74 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS33715 b2c946937483a222a12e8483a0476daf 302 SUPERFAMILY SSF51430 1 295 5.76E-73 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS24050 4b80c58999b1f234c26e9170987a9913 299 SUPERFAMILY SSF51735 1 284 2.01E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS24050 4b80c58999b1f234c26e9170987a9913 299 Gene3D G3DSA:3.40.50.720 1 236 1.4E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS24050 4b80c58999b1f234c26e9170987a9913 299 Pfam PF08338 Domain of unknown function (DUF1731) 248 293 1.8E-18 T 06-07-2017 IPR013549 Domain of unknown function DUF1731 SMD11_RS24050 4b80c58999b1f234c26e9170987a9913 299 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 291 1.6E-101 T 06-07-2017 IPR010099 Epimerase family protein SDR39U1 SMD11_RS24050 4b80c58999b1f234c26e9170987a9913 299 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 212 2.9E-13 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 SMD11_RS29415 768c6110ee0563bb5fe1ca3815092386 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.3E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29415 768c6110ee0563bb5fe1ca3815092386 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 1.3E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29415 768c6110ee0563bb5fe1ca3815092386 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.3E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29415 768c6110ee0563bb5fe1ca3815092386 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.3E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29415 768c6110ee0563bb5fe1ca3815092386 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.3E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR SMD11_RS29415 768c6110ee0563bb5fe1ca3815092386 250 SUPERFAMILY SSF51735 14 249 1.52E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS29415 768c6110ee0563bb5fe1ca3815092386 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 247 1.7E-34 T 06-07-2017 SMD11_RS29415 768c6110ee0563bb5fe1ca3815092386 250 Gene3D G3DSA:3.40.50.720 15 248 1.8E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS33575 fd7cc48f2b436ec336e246a277d747d0 297 Gene3D G3DSA:3.10.129.10 128 289 1.4E-42 T 06-07-2017 IPR029069 HotDog domain SMD11_RS33575 fd7cc48f2b436ec336e246a277d747d0 297 SUPERFAMILY SSF54637 121 288 1.3E-41 T 06-07-2017 IPR029069 HotDog domain SMD11_RS33575 fd7cc48f2b436ec336e246a277d747d0 297 Pfam PF13622 Thioesterase-like superfamily 34 287 4.7E-59 T 06-07-2017 SMD11_RS33575 fd7cc48f2b436ec336e246a277d747d0 297 Gene3D G3DSA:3.10.129.10 9 119 3.9E-34 T 06-07-2017 IPR029069 HotDog domain SMD11_RS33575 fd7cc48f2b436ec336e246a277d747d0 297 SUPERFAMILY SSF54637 9 118 1.32E-31 T 06-07-2017 IPR029069 HotDog domain SMD11_RS18410 cec965211013c940e8448e4e97a9df45 107 Pfam PF13396 Phospholipase_D-nuclease N-terminal 12 59 6.0E-12 T 06-07-2017 IPR027379 Cardiolipin synthase N-terminal SMD11_RS12415 9ceede6f61a2c04505358aaf5fbefc4f 240 Pfam PF03006 Haemolysin-III related 32 229 2.0E-45 T 06-07-2017 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 SMD11_RS14520 cb91506ddd59c3ca584c7d4cdd6acfb0 125 Pfam PF01381 Helix-turn-helix 13 65 2.1E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS14520 cb91506ddd59c3ca584c7d4cdd6acfb0 125 SUPERFAMILY SSF47413 8 69 2.95E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS14520 cb91506ddd59c3ca584c7d4cdd6acfb0 125 Gene3D G3DSA:1.10.260.40 8 109 2.3E-22 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS14520 cb91506ddd59c3ca584c7d4cdd6acfb0 125 SMART SM00530 12 67 6.6E-16 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS17125 5f5b27333b17dda4277a8e704b12813e 95 PIRSF PIRSF030200 1 95 2.1E-43 T 06-07-2017 IPR009359 Phenylacetic acid degradation B SMD11_RS17125 5f5b27333b17dda4277a8e704b12813e 95 Pfam PF06243 Phenylacetic acid degradation B 5 91 2.0E-40 T 06-07-2017 IPR009359 Phenylacetic acid degradation B SMD11_RS17125 5f5b27333b17dda4277a8e704b12813e 95 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 6 94 4.0E-43 T 06-07-2017 IPR009359 Phenylacetic acid degradation B SMD11_RS12725 e368782728854deb2c10d0f055ba57cb 184 Pfam PF04892 VanZ like family 27 144 5.1E-8 T 06-07-2017 IPR006976 VanZ-like SMD11_RS21245 9d0928e984d83fe3ea391c165f98113d 437 Pfam PF02378 Phosphotransferase system, EIIC 27 356 6.1E-63 T 06-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SMD11_RS20105 0ebd6fc3e7b0aae4c5d58398ffaad6bb 638 Pfam PF13360 PQQ-like domain 265 374 2.5E-4 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat SMD11_RS20105 0ebd6fc3e7b0aae4c5d58398ffaad6bb 638 SUPERFAMILY SSF50998 270 545 1.53E-10 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily SMD11_RS20105 0ebd6fc3e7b0aae4c5d58398ffaad6bb 638 Gene3D G3DSA:2.130.10.10 523 589 2.7E-6 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS20105 0ebd6fc3e7b0aae4c5d58398ffaad6bb 638 Gene3D G3DSA:2.130.10.10 292 431 2.7E-6 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS27950 64097a82efa8981782e35f93ca0f985b 116 Gene3D G3DSA:1.10.10.60 58 88 2.0E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS17385 f0f4eddae62b1d3995087f64da585438 392 SUPERFAMILY SSF53474 126 383 2.34E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS17385 f0f4eddae62b1d3995087f64da585438 392 Gene3D G3DSA:3.40.50.1820 126 384 3.4E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS17385 f0f4eddae62b1d3995087f64da585438 392 Pfam PF00756 Putative esterase 145 284 2.1E-14 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 SMD11_RS13470 d1c031a6e79bdf6a56d05b14bd85f403 249 SUPERFAMILY SSF55729 127 165 5.06E-7 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS13470 d1c031a6e79bdf6a56d05b14bd85f403 249 SUPERFAMILY SSF55729 58 92 5.06E-7 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS13470 d1c031a6e79bdf6a56d05b14bd85f403 249 Gene3D G3DSA:3.40.630.30 123 164 7.4E-5 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS13470 d1c031a6e79bdf6a56d05b14bd85f403 249 Gene3D G3DSA:3.40.630.30 62 87 7.4E-5 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS13790 e079ad136ec5904f329d640879d30b7a 302 Pfam PF11228 Protein of unknown function (DUF3027) 31 256 6.3E-82 T 06-07-2017 IPR021391 Protein of unknown function DUF3027 SMD11_RS13795 fdf2efade606ad640d02b1eb53e336eb 478 Gene3D G3DSA:1.20.1250.20 278 461 2.0E-6 T 06-07-2017 SMD11_RS13795 fdf2efade606ad640d02b1eb53e336eb 478 Gene3D G3DSA:1.20.1250.20 86 232 1.4E-7 T 06-07-2017 SMD11_RS13795 fdf2efade606ad640d02b1eb53e336eb 478 SUPERFAMILY SSF103473 75 240 1.57E-21 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS13795 fdf2efade606ad640d02b1eb53e336eb 478 SUPERFAMILY SSF103473 274 459 1.57E-21 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS13795 fdf2efade606ad640d02b1eb53e336eb 478 Pfam PF07690 Major Facilitator Superfamily 81 431 5.2E-18 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS26780 b9d35591e4c85f2ec3c5bb442103aa17 212 Pfam PF13460 NAD(P)H-binding 7 201 6.4E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS26780 b9d35591e4c85f2ec3c5bb442103aa17 212 SUPERFAMILY SSF51735 1 211 1.1E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS26780 b9d35591e4c85f2ec3c5bb442103aa17 212 Gene3D G3DSA:3.40.50.720 1 212 2.4E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS32165 2fe9ec55a35b216cd0989b65942986a7 274 Pfam PF06724 Domain of Unknown Function (DUF1206) 108 178 7.0E-14 T 06-07-2017 IPR009597 Domain of unknown function DUF1206 SMD11_RS32165 2fe9ec55a35b216cd0989b65942986a7 274 Pfam PF06724 Domain of Unknown Function (DUF1206) 204 272 5.6E-17 T 06-07-2017 IPR009597 Domain of unknown function DUF1206 SMD11_RS32165 2fe9ec55a35b216cd0989b65942986a7 274 Pfam PF06724 Domain of Unknown Function (DUF1206) 24 91 2.6E-22 T 06-07-2017 IPR009597 Domain of unknown function DUF1206 SMD11_RS25900 e05677c7ea5bfd25bded05f495f0859b 87 Pfam PF05121 Gas vesicle protein K 2 84 9.5E-35 T 06-07-2017 IPR007805 Gas vesicle protein GvpK GO:0031412 SMD11_RS23210 34ffffcea786344f9bf1cbecec217a5f 231 SUPERFAMILY SSF51182 22 224 1.51E-47 T 06-07-2017 IPR011051 RmlC-like cupin domain SMD11_RS23210 34ffffcea786344f9bf1cbecec217a5f 231 Pfam PF02678 Pirin 22 124 1.8E-31 T 06-07-2017 IPR003829 Pirin, N-terminal domain SMD11_RS23210 34ffffcea786344f9bf1cbecec217a5f 231 Gene3D G3DSA:2.60.120.10 22 139 2.6E-43 T 06-07-2017 IPR014710 RmlC-like jelly roll fold SMD11_RS22050 af0b8ce6fb2cc819d9b8a1aaa216e5d2 331 SUPERFAMILY SSF49879 229 325 2.87E-19 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 SMD11_RS22050 af0b8ce6fb2cc819d9b8a1aaa216e5d2 331 Gene3D G3DSA:2.60.200.20 235 324 7.0E-18 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS22050 af0b8ce6fb2cc819d9b8a1aaa216e5d2 331 SMART SM00240 242 302 0.0026 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS22050 af0b8ce6fb2cc819d9b8a1aaa216e5d2 331 Pfam PF00498 FHA domain 243 321 1.2E-12 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 SMD11_RS02555 8a291d1bc677cdecd4fcba934cedf2a7 816 SUPERFAMILY SSF48371 483 612 2.69E-5 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 SMD11_RS19495 26d37323c42ef1c3330c932ed0df8e9c 289 SUPERFAMILY SSF47413 10 69 4.38E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS19495 26d37323c42ef1c3330c932ed0df8e9c 289 Gene3D G3DSA:1.10.260.40 9 69 4.7E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS19495 26d37323c42ef1c3330c932ed0df8e9c 289 SMART SM00530 17 73 1.2E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS19495 26d37323c42ef1c3330c932ed0df8e9c 289 Pfam PF13560 Helix-turn-helix domain 13 77 1.5E-14 T 06-07-2017 SMD11_RS17995 74042968e24446d918fd4ace31c718d2 116 Pfam PF06262 Zinicin-like metallopeptidase 28 114 1.6E-34 T 06-07-2017 IPR010428 Zinicin-like metallopeptidase SMD11_RS17995 74042968e24446d918fd4ace31c718d2 116 SUPERFAMILY SSF55486 2 115 2.72E-40 T 06-07-2017 SMD11_RS08880 136ef09aa1ca674e37e0edf51e65d6ae 81 Pfam PF14013 MT0933-like antitoxin protein 15 63 1.7E-17 T 06-07-2017 IPR028037 Antitoxin Rv0909/MT0933 SMD11_RS10690 943f400b6a3e6a0c3e9ef0c16be1bcb8 338 SMART SM00382 26 204 6.8E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS10690 943f400b6a3e6a0c3e9ef0c16be1bcb8 338 Gene3D G3DSA:3.40.50.300 1 224 2.8E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10690 943f400b6a3e6a0c3e9ef0c16be1bcb8 338 SUPERFAMILY SSF52540 2 225 1.05E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10690 943f400b6a3e6a0c3e9ef0c16be1bcb8 338 Pfam PF00005 ABC transporter 18 156 9.0E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS14570 04d84cfe47caf683b8c1e1ca6b66e516 332 Pfam PF01384 Phosphate transporter family 20 166 3.4E-40 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 SMD11_RS14570 04d84cfe47caf683b8c1e1ca6b66e516 332 Pfam PF01384 Phosphate transporter family 165 320 1.6E-46 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 SMD11_RS04410 4cb32c10b09edf7373d2133ae47b452c 325 Pfam PF02653 Branched-chain amino acid transport system / permease component 50 313 2.2E-48 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD11_RS34600 a4d5ffe4ff9ca6ed084e6483bd7e4331 194 SUPERFAMILY SSF54909 132 175 5.83E-5 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS34600 a4d5ffe4ff9ca6ed084e6483bd7e4331 194 Pfam PF03992 Antibiotic biosynthesis monooxygenase 131 172 1.9E-5 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain SMD11_RS34600 a4d5ffe4ff9ca6ed084e6483bd7e4331 194 Gene3D G3DSA:3.30.70.900 132 175 9.2E-7 T 06-07-2017 SMD11_RS34600 a4d5ffe4ff9ca6ed084e6483bd7e4331 194 Gene3D G3DSA:3.30.70.900 12 113 1.9E-10 T 06-07-2017 SMD11_RS09525 f971d7f822a8f44cd9f197f5dd2220f2 217 SUPERFAMILY SSF51261 96 203 1.36E-10 T 06-07-2017 IPR011055 Duplicated hybrid motif SMD11_RS09525 f971d7f822a8f44cd9f197f5dd2220f2 217 Pfam PF01551 Peptidase family M23 102 199 2.9E-11 T 06-07-2017 IPR016047 Peptidase M23 SMD11_RS09525 f971d7f822a8f44cd9f197f5dd2220f2 217 Gene3D G3DSA:2.70.70.10 72 204 3.2E-19 T 06-07-2017 SMD11_RS26980 db64828fea611fdb36bad594364d25ae 213 Gene3D G3DSA:3.40.630.30 8 193 8.2E-48 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS26980 db64828fea611fdb36bad594364d25ae 213 Pfam PF13302 Acetyltransferase (GNAT) domain 14 154 3.3E-28 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS26980 db64828fea611fdb36bad594364d25ae 213 SUPERFAMILY SSF55729 7 173 7.54E-39 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS20955 f163b6e9492bd3dc14dfe17951281b2c 162 Gene3D G3DSA:2.40.280.10 8 128 3.9E-53 T 06-07-2017 IPR023620 Small protein B SMD11_RS20955 f163b6e9492bd3dc14dfe17951281b2c 162 Pfam PF01668 SmpB protein 10 72 1.3E-30 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 SMD11_RS20955 f163b6e9492bd3dc14dfe17951281b2c 162 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 133 3.0E-56 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 SMD11_RS20955 f163b6e9492bd3dc14dfe17951281b2c 162 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 06-07-2017 IPR020081 SsrA-binding protein, conserved site SMD11_RS20955 f163b6e9492bd3dc14dfe17951281b2c 162 TIGRFAM TIGR00086 smpB: SsrA-binding protein 10 150 4.3E-58 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 SMD11_RS20955 f163b6e9492bd3dc14dfe17951281b2c 162 SUPERFAMILY SSF74982 4 133 3.53E-53 T 06-07-2017 IPR023620 Small protein B SMD11_RS20955 f163b6e9492bd3dc14dfe17951281b2c 162 Hamap MF_00023 SsrA-binding protein [smpB]. 1 159 73.602 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 SMD11_RS22430 c1210e69764218f370414dc0e1efe897 640 Pfam PF04055 Radical SAM superfamily 268 429 3.0E-14 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS22430 c1210e69764218f370414dc0e1efe897 640 SUPERFAMILY SSF102114 232 635 8.76E-52 T 06-07-2017 SMD11_RS22430 c1210e69764218f370414dc0e1efe897 640 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 12 618 2.8E-213 T 06-07-2017 IPR023862 Conserved hypothetical protein CHP03960, radical SAM SMD11_RS22430 c1210e69764218f370414dc0e1efe897 640 SMART SM00729 264 487 9.0E-29 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD11_RS22430 c1210e69764218f370414dc0e1efe897 640 Gene3D G3DSA:3.80.30.20 263 492 1.4E-44 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe SMD11_RS31625 f067d128f5d2bec4d2c5fbd4548f134f 143 SUPERFAMILY SSF46785 30 137 2.31E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS31625 f067d128f5d2bec4d2c5fbd4548f134f 143 Gene3D G3DSA:1.10.10.10 27 138 1.0E-44 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS31625 f067d128f5d2bec4d2c5fbd4548f134f 143 Pfam PF01638 HxlR-like helix-turn-helix 41 126 3.5E-25 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type SMD11_RS02220 ca81f5e6021dafffedc2e71abf419203 424 Pfam PF14065 Protein of unknown function (DUF4255) 9 192 4.3E-38 T 06-07-2017 IPR025351 Protein of unknown function DUF4255 SMD11_RS23965 b591d9542fdcb6fd33334971b6e7f84e 174 SUPERFAMILY SSF46785 3 167 6.43E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS23965 b591d9542fdcb6fd33334971b6e7f84e 174 Pfam PF03551 Transcriptional regulator PadR-like family 7 77 2.8E-15 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal SMD11_RS23965 b591d9542fdcb6fd33334971b6e7f84e 174 Gene3D G3DSA:1.10.10.10 1 87 1.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02830 33fc97869f96c7bb509c0dc8fc66b38c 70 Pfam PF14117 Domain of unknown function (DUF4287) 7 63 1.4E-28 T 06-07-2017 IPR025629 Protein of unknown function DUF4287 SMD11_RS20460 9cb03c3ec5d237623c17a369c072dc97 341 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 76 254 2.5E-21 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS20460 9cb03c3ec5d237623c17a369c072dc97 341 SUPERFAMILY SSF52266 71 269 1.21E-28 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS20460 9cb03c3ec5d237623c17a369c072dc97 341 Gene3D G3DSA:3.40.50.1110 76 267 3.9E-24 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS25715 ab7a64988c8b07c1bc2b65e6d8871c71 432 Pfam PF06245 Protein of unknown function (DUF1015) 19 427 4.7E-109 T 06-07-2017 IPR008323 Uncharacterised conserved protein UCP033563 SMD11_RS25715 ab7a64988c8b07c1bc2b65e6d8871c71 432 PIRSF PIRSF033563 16 431 7.0E-110 T 06-07-2017 IPR008323 Uncharacterised conserved protein UCP033563 SMD11_RS04055 e64a696b5fd09bc322484996ce2d372e 293 SUPERFAMILY SSF159713 67 253 1.96E-16 T 06-07-2017 SMD11_RS04055 e64a696b5fd09bc322484996ce2d372e 293 Pfam PF04016 Putative heavy-metal chelation 142 252 5.5E-8 T 06-07-2017 IPR007161 Putative heavy-metal chelation domain SMD11_RS10470 4375a5fe3b77bcda57728e541cb20833 564 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 439 5.1E-70 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS10470 4375a5fe3b77bcda57728e541cb20833 564 SUPERFAMILY SSF103473 12 205 3.4E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS10470 4375a5fe3b77bcda57728e541cb20833 564 SUPERFAMILY SSF103473 255 426 3.4E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS10470 4375a5fe3b77bcda57728e541cb20833 564 SUPERFAMILY SSF103473 507 533 3.4E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS10470 4375a5fe3b77bcda57728e541cb20833 564 Gene3D G3DSA:1.20.1250.20 22 200 1.3E-31 T 06-07-2017 SMD11_RS10470 4375a5fe3b77bcda57728e541cb20833 564 Gene3D G3DSA:1.20.1250.20 508 536 1.7E-16 T 06-07-2017 SMD11_RS10470 4375a5fe3b77bcda57728e541cb20833 564 Gene3D G3DSA:1.20.1250.20 271 427 1.7E-16 T 06-07-2017 SMD11_RS10470 4375a5fe3b77bcda57728e541cb20833 564 Pfam PF07690 Major Facilitator Superfamily 26 416 1.2E-46 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS31665 ce89aead821e364faeb13f1d39adc1e4 148 SUPERFAMILY SSF53927 6 145 1.51E-33 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 SMD11_RS31665 ce89aead821e364faeb13f1d39adc1e4 148 Gene3D G3DSA:3.40.140.10 5 137 8.1E-31 T 06-07-2017 SMD11_RS31665 ce89aead821e364faeb13f1d39adc1e4 148 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 7 100 1.3E-16 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 SMD11_RS21425 8489d919dfe687cd610a6a597453ec7e 126 SUPERFAMILY SSF46785 14 117 4.51E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS21425 8489d919dfe687cd610a6a597453ec7e 126 Pfam PF01638 HxlR-like helix-turn-helix 25 110 3.1E-24 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type SMD11_RS21425 8489d919dfe687cd610a6a597453ec7e 126 Gene3D G3DSA:1.10.10.10 11 121 1.4E-38 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS10310 4bfbc3f06679eb14e2c7f7f867d2a51d 176 Gene3D G3DSA:2.80.10.50 33 172 1.1E-4 T 06-07-2017 SMD11_RS10310 4bfbc3f06679eb14e2c7f7f867d2a51d 176 SUPERFAMILY SSF50370 34 173 1.4E-7 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS20645 b570a132be5c7a871ee41ee4efa5b3d3 417 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 81 236 6.2E-42 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS20645 b570a132be5c7a871ee41ee4efa5b3d3 417 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 81 236 1.2E-45 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS09010 dc5179c7955ba739ce5bd3afb5eb8e3e 274 Gene3D G3DSA:1.10.260.40 13 84 3.1E-4 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS09010 dc5179c7955ba739ce5bd3afb5eb8e3e 274 Pfam PF13413 Helix-turn-helix domain 23 82 2.3E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS09010 dc5179c7955ba739ce5bd3afb5eb8e3e 274 Pfam PF13464 Domain of unknown function (DUF4115) 193 265 4.4E-17 T 06-07-2017 IPR025194 Domain of unknown function DUF4115 SMD11_RS23170 948188f9e3c184dc28e3c7611c8562c4 164 Pfam PF11343 Protein of unknown function (DUF3145) 6 162 1.1E-73 T 06-07-2017 IPR021491 Protein of unknown function DUF3145 SMD11_RS11365 abd207ae42b7a69c46db3e4ca0fab08a 138 Pfam PF03795 YCII-related domain 1 108 6.3E-21 T 06-07-2017 IPR005545 YCII-related SMD11_RS11365 abd207ae42b7a69c46db3e4ca0fab08a 138 SUPERFAMILY SSF54909 1 111 9.92E-29 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS11365 abd207ae42b7a69c46db3e4ca0fab08a 138 Gene3D G3DSA:3.30.70.1060 1 111 1.3E-35 T 06-07-2017 SMD11_RS25660 bc9be94eac1a67188f4a52037df56006 256 Pfam PF01925 Sulfite exporter TauE/SafE 10 253 9.4E-36 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 SMD11_RS24730 851dd611d791e5083962b6edd5205459 508 Gene3D G3DSA:3.60.120.10 22 501 5.1E-178 T 06-07-2017 IPR005801 ADC synthase GO:0009058 SMD11_RS24730 851dd611d791e5083962b6edd5205459 508 PRINTS PR00095 Anthranilate synthase component I signature 338 351 6.4E-24 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD11_RS24730 851dd611d791e5083962b6edd5205459 508 PRINTS PR00095 Anthranilate synthase component I signature 447 461 6.4E-24 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD11_RS24730 851dd611d791e5083962b6edd5205459 508 PRINTS PR00095 Anthranilate synthase component I signature 352 365 6.4E-24 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD11_RS24730 851dd611d791e5083962b6edd5205459 508 PRINTS PR00095 Anthranilate synthase component I signature 432 446 6.4E-24 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD11_RS24730 851dd611d791e5083962b6edd5205459 508 Pfam PF00425 chorismate binding enzyme 239 490 1.5E-99 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal SMD11_RS24730 851dd611d791e5083962b6edd5205459 508 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 35 499 5.8E-175 T 06-07-2017 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD11_RS24730 851dd611d791e5083962b6edd5205459 508 Pfam PF04715 Anthranilate synthase component I, N terminal region 36 179 6.5E-30 T 06-07-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 SMD11_RS24730 851dd611d791e5083962b6edd5205459 508 SUPERFAMILY SSF56322 24 498 8.11E-160 T 06-07-2017 IPR005801 ADC synthase GO:0009058 SMD11_RS05025 32bb7a3429c691ab0a727a9ec2ced8fe 227 SUPERFAMILY SSF47413 19 81 7.11E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS05025 32bb7a3429c691ab0a727a9ec2ced8fe 227 Pfam PF13560 Helix-turn-helix domain 19 76 1.9E-11 T 06-07-2017 SMD11_RS05025 32bb7a3429c691ab0a727a9ec2ced8fe 227 SUPERFAMILY SSF50475 98 223 5.24E-21 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS05025 32bb7a3429c691ab0a727a9ec2ced8fe 227 Gene3D G3DSA:1.10.260.40 20 85 3.3E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS05025 32bb7a3429c691ab0a727a9ec2ced8fe 227 Gene3D G3DSA:2.30.110.10 94 225 1.1E-38 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS05025 32bb7a3429c691ab0a727a9ec2ced8fe 227 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 104 222 8.9E-23 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related SMD11_RS05025 32bb7a3429c691ab0a727a9ec2ced8fe 227 SMART SM00530 23 78 3.9E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SMD11_RS07240 71508699ab7b2b95f1a012e3beadfac5 218 Pfam PF01810 LysE type translocator 14 213 1.1E-28 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 SMD11_RS07240 71508699ab7b2b95f1a012e3beadfac5 218 PIRSF PIRSF006324 2 218 2.3E-48 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 SMD11_RS07240 71508699ab7b2b95f1a012e3beadfac5 218 SUPERFAMILY SSF103473 3 213 9.16E-5 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS01030 1a78da8942dd8796f6f952598790487f 182 Gene3D G3DSA:1.20.120.450 13 181 3.8E-45 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase SMD11_RS01030 1a78da8942dd8796f6f952598790487f 182 SUPERFAMILY SSF109854 13 177 1.22E-41 T 06-07-2017 SMD11_RS01030 1a78da8942dd8796f6f952598790487f 182 Pfam PF04978 Protein of unknown function (DUF664) 32 178 9.5E-44 T 06-07-2017 IPR007061 Protein of unknown function DUF664 SMD11_RS24620 71515a43843c3910b02ab0159e93773c 273 SUPERFAMILY SSF52833 84 250 2.07E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS24620 71515a43843c3910b02ab0159e93773c 273 Gene3D G3DSA:3.40.30.10 86 271 4.2E-21 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS24620 71515a43843c3910b02ab0159e93773c 273 Pfam PF13462 Thioredoxin 85 267 4.7E-35 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS05040 4eda1d79561e3dde1130eb14159700bc 71 Pfam PF08940 Domain of unknown function (DUF1918) 1 58 2.4E-27 T 06-07-2017 IPR015035 Domain of unknown function DUF1918 SMD11_RS05040 4eda1d79561e3dde1130eb14159700bc 71 SUPERFAMILY SSF50118 1 65 2.81E-24 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SMD11_RS17230 566b2655f3d980f818984dcec8dc9153 153 Gene3D G3DSA:2.30.110.10 15 137 5.0E-7 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS17230 566b2655f3d980f818984dcec8dc9153 153 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 18 104 6.5E-10 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related SMD11_RS13810 aa05e8c64b91db313e2665ea090e3186 283 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 4 273 39.471 T 06-07-2017 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 SMD11_RS13810 aa05e8c64b91db313e2665ea090e3186 283 Pfam PF02621 Menaquinone biosynthesis 5 267 1.4E-86 T 06-07-2017 IPR003773 Menaquinone biosynthesis enzyme SMD11_RS13810 aa05e8c64b91db313e2665ea090e3186 283 SUPERFAMILY SSF53850 5 272 6.59E-81 T 06-07-2017 SMD11_RS13810 aa05e8c64b91db313e2665ea090e3186 283 Gene3D G3DSA:3.40.190.10 79 182 4.0E-14 T 06-07-2017 SMD11_RS21950 81a36e30abba49b5c2586d0737832c10 156 TIGRFAM TIGR00494 crcB: protein CrcB 33 144 2.6E-24 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMD11_RS21950 81a36e30abba49b5c2586d0737832c10 156 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 31 148 17.738 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMD11_RS21950 81a36e30abba49b5c2586d0737832c10 156 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 33 142 1.2E-20 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 SMD11_RS26260 2bb768f3631e3f29de7e969c5e459a1d 360 Pfam PF01636 Phosphotransferase enzyme family 53 270 8.3E-50 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase SMD11_RS26260 2bb768f3631e3f29de7e969c5e459a1d 360 SUPERFAMILY SSF56112 27 333 2.27E-63 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS26260 2bb768f3631e3f29de7e969c5e459a1d 360 Gene3D G3DSA:3.90.1200.10 130 316 3.9E-33 T 06-07-2017 SMD11_RS13360 02f0a97485d9adae189629a2c9fc5ca1 339 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 301 337 2.5E-5 T 06-07-2017 IPR019931 LPXTG cell wall anchor domain SMD11_RS33525 8d7633d54a176e9fccafa8939efeb532 450 SUPERFAMILY SSF54909 2 428 2.68E-123 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS33525 8d7633d54a176e9fccafa8939efeb532 450 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 154 423 9.3E-33 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 SMD11_RS14115 8eaad9bff74e9cf9dc92e7a266be3ec5 542 Pfam PF07681 DoxX 213 314 1.1E-9 T 06-07-2017 IPR032808 DoxX family SMD11_RS27430 8a6f08b943770c44c14af5aa64b691f9 338 SUPERFAMILY SSF100950 74 319 1.79E-55 T 06-07-2017 SMD11_RS27430 8a6f08b943770c44c14af5aa64b691f9 338 Gene3D G3DSA:3.40.50.1360 63 319 6.1E-68 T 06-07-2017 SMD11_RS27430 8a6f08b943770c44c14af5aa64b691f9 338 Pfam PF04198 Putative sugar-binding domain 70 319 7.1E-66 T 06-07-2017 IPR007324 Sugar-binding domain, putative GO:0030246 SMD11_RS11530 62e91c885a27f32878146ff98a1cfabe 252 Gene3D G3DSA:3.60.160.10 20 218 5.9E-33 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 SMD11_RS11530 62e91c885a27f32878146ff98a1cfabe 252 Pfam PF01987 Mitochondrial biogenesis AIM24 21 215 1.8E-29 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 SMD11_RS11530 62e91c885a27f32878146ff98a1cfabe 252 SUPERFAMILY SSF51219 19 224 5.75E-41 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SMD11_RS33585 4bfd5ae087ff61d453ba27d8d188c8c7 484 Pfam PF04055 Radical SAM superfamily 74 237 3.5E-13 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 SMD11_RS33585 4bfd5ae087ff61d453ba27d8d188c8c7 484 SMART SM00729 58 280 2.8E-27 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SMD11_RS33585 4bfd5ae087ff61d453ba27d8d188c8c7 484 Gene3D G3DSA:3.80.30.20 73 261 6.3E-22 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe SMD11_RS33585 4bfd5ae087ff61d453ba27d8d188c8c7 484 SUPERFAMILY SSF102114 55 442 3.01E-69 T 06-07-2017 SMD11_RS22165 0d61f852a2ff9e4146ca2475984b6c80 324 Pfam PF03405 Fatty acid desaturase 19 312 2.8E-75 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 SMD11_RS22165 0d61f852a2ff9e4146ca2475984b6c80 324 PIRSF PIRSF000346 2 322 3.5E-110 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 SMD11_RS22165 0d61f852a2ff9e4146ca2475984b6c80 324 SUPERFAMILY SSF47240 11 318 4.47E-82 T 06-07-2017 IPR009078 Ferritin-like superfamily SMD11_RS22165 0d61f852a2ff9e4146ca2475984b6c80 324 Gene3D G3DSA:1.10.620.20 12 312 4.9E-109 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 SMD11_RS12165 dc085f2756d829941ca053fca92b2b6e 250 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 146 213 1.5E-9 T 06-07-2017 IPR024425 Cell wall-active antibiotics response 4TMS YvqF SMD11_RS12165 dc085f2756d829941ca053fca92b2b6e 250 Pfam PF08044 Domain of unknown function (DUF1707) 40 92 5.5E-23 T 06-07-2017 IPR012551 Protein of unknown function DUF1707 SMD11_RS05775 4f5bbb639184cce749a11a34e0c80163 364 PIRSF PIRSF026166 11 342 3.0E-123 T 06-07-2017 IPR016833 Putative sodium bile acid cotransporter SMD11_RS05775 4f5bbb639184cce749a11a34e0c80163 364 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 22 328 4.8E-91 T 06-07-2017 IPR016833 Putative sodium bile acid cotransporter SMD11_RS01720 b728ea27fc217255ec94713c2eba5155 204 Pfam PF14124 Domain of unknown function (DUF4291) 8 185 4.2E-70 T 06-07-2017 IPR025633 Protein of unknown function DUF4291 SMD11_RS34430 768b2230ada620f9f2903545222dc6b0 267 Pfam PF08889 WbqC-like protein family 31 216 4.4E-31 T 06-07-2017 IPR014985 WbqC-like protein family SMD11_RS11490 803c4296959ca9130de9b2e10f318808 970 Pfam PF03699 Uncharacterised protein family (UPF0182) 27 813 2.1E-286 T 06-07-2017 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 SMD11_RS11490 803c4296959ca9130de9b2e10f318808 970 Hamap MF_01600 UPF0182 protein . 17 889 18.585 T 06-07-2017 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 SMD11_RS22420 e77d80a50c21803fc3c43335b79e7fc5 399 Pfam PF01098 Cell cycle protein 35 394 7.5E-95 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 SMD11_RS22420 e77d80a50c21803fc3c43335b79e7fc5 399 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 353 377 - T 06-07-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 SMD11_RS22420 e77d80a50c21803fc3c43335b79e7fc5 399 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 33 395 1.7E-105 T 06-07-2017 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 SMD11_RS27050 9ae24a3380d1e76ecdc27717b656b3f9 273 Gene3D G3DSA:3.30.470.10 2 101 2.1E-32 T 06-07-2017 SMD11_RS27050 9ae24a3380d1e76ecdc27717b656b3f9 273 Gene3D G3DSA:3.20.10.10 124 258 8.4E-42 T 06-07-2017 SMD11_RS27050 9ae24a3380d1e76ecdc27717b656b3f9 273 SUPERFAMILY SSF56752 3 265 1.96E-70 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD11_RS27050 9ae24a3380d1e76ecdc27717b656b3f9 273 ProSitePatterns PS00770 Aminotransferases class-IV signature. 174 203 - T 06-07-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD11_RS27050 9ae24a3380d1e76ecdc27717b656b3f9 273 Pfam PF01063 Amino-transferase class IV 29 242 5.6E-50 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SMD11_RS11270 1dcaec2251b4be08cd0fd9402e6cb027 494 SUPERFAMILY SSF51445 15 331 5.58E-78 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS11270 1dcaec2251b4be08cd0fd9402e6cb027 494 Gene3D G3DSA:3.20.20.300 12 332 4.2E-93 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD11_RS11270 1dcaec2251b4be08cd0fd9402e6cb027 494 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 34 327 1.5E-73 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 SMD11_RS32410 69d6cb8f0b17062448c43f2669f96780 146 Gene3D G3DSA:1.10.260.40 36 120 8.4E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS26345 76d1db06812ea648b0c05704b18c3e04 327 Pfam PF00248 Aldo/keto reductase family 15 312 2.0E-59 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS26345 76d1db06812ea648b0c05704b18c3e04 327 Gene3D G3DSA:3.20.20.100 9 321 4.4E-86 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS26345 76d1db06812ea648b0c05704b18c3e04 327 SUPERFAMILY SSF51430 1 316 1.57E-86 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS21355 a2c3fd18beb90385c292d12dcb15f9ef 237 Pfam PF08044 Domain of unknown function (DUF1707) 8 60 3.0E-24 T 06-07-2017 IPR012551 Protein of unknown function DUF1707 SMD11_RS30575 c3c5938e27a6ce2e9a34b7cb317f78f4 110 Pfam PF13602 Zinc-binding dehydrogenase 7 108 2.5E-9 T 06-07-2017 SMD11_RS33150 e0dea38d299e385104a3ce7d042f15c2 103 Pfam PF05488 PAAR motif 7 90 2.7E-19 T 06-07-2017 IPR008727 PAAR motif SMD11_RS12985 bd7303c0b77ae417c58d4926a6ba06c9 412 SUPERFAMILY SSF52777 13 132 1.78E-5 T 06-07-2017 SMD11_RS32785 12bab6e235df0cb4a091fe9e0538a93c 354 Gene3D G3DSA:1.25.40.10 134 180 1.2E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS32785 12bab6e235df0cb4a091fe9e0538a93c 354 Gene3D G3DSA:1.25.40.10 291 315 1.2E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS21605 d563afdd4527facb8cf01f4662277140 196 SUPERFAMILY SSF81296 28 196 1.27E-59 T 06-07-2017 IPR014756 Immunoglobulin E-set SMD11_RS21605 d563afdd4527facb8cf01f4662277140 196 Gene3D G3DSA:2.70.50.50 28 196 8.6E-64 T 06-07-2017 SMD11_RS21605 d563afdd4527facb8cf01f4662277140 196 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 28 194 4.1E-42 T 06-07-2017 IPR004302 Chitin-binding protein, N-terminal SMD11_RS19040 6f5485a659d4ecaff5e8457c438367d5 706 Gene3D G3DSA:3.40.50.2000 197 354 4.3E-24 T 06-07-2017 SMD11_RS19040 6f5485a659d4ecaff5e8457c438367d5 706 SUPERFAMILY SSF53756 11 377 8.85E-66 T 06-07-2017 SMD11_RS19040 6f5485a659d4ecaff5e8457c438367d5 706 Pfam PF00534 Glycosyl transferases group 1 197 354 6.6E-38 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 SMD11_RS05290 490a08e42ef6d477d3d5bfac44614bf9 263 Gene3D G3DSA:3.40.50.1110 16 202 2.3E-37 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS05290 490a08e42ef6d477d3d5bfac44614bf9 263 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 18 191 2.9E-25 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS05290 490a08e42ef6d477d3d5bfac44614bf9 263 SUPERFAMILY SSF52266 16 201 8.55E-34 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS22765 a828265c587daa1c68543a99f036522d 330 Gene3D G3DSA:3.40.50.300 118 322 2.9E-102 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22765 a828265c587daa1c68543a99f036522d 330 SUPERFAMILY SSF52540 112 294 2.72E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22765 a828265c587daa1c68543a99f036522d 330 Pfam PF02562 PhoH-like protein 119 322 3.3E-95 T 06-07-2017 IPR003714 PhoH-like protein GO:0005524 SMD11_RS20890 58a352ca6600b9ee40ff0b43ad9924a7 567 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 45 197 3.2E-15 T 06-07-2017 SMD11_RS17620 24dbc798f710b0e1f98152afe39b2864 223 Pfam PF13707 RloB-like protein 53 220 1.2E-29 T 06-07-2017 IPR025591 RloB-like protein SMD11_RS06145 0b7fff3e4d2bc8c6c54b6b435e71dc6d 234 Pfam PF11774 Lsr2 1 110 7.2E-32 T 06-07-2017 IPR024412 Lsr2 SMD11_RS06145 0b7fff3e4d2bc8c6c54b6b435e71dc6d 234 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 110 4.0E-23 T 06-07-2017 IPR024412 Lsr2 SMD11_RS22700 330eeaa18ad3fe9fdd0f10ddf595f5cc 401 Pfam PF06889 Protein of unknown function (DUF1266) 197 388 5.2E-34 T 06-07-2017 IPR009677 Protein of unknown function DUF1266 SMD11_RS25490 24e179a9b9d34666d0d9bab920d8ca58 286 Pfam PF02104 SURF1 family 19 227 1.4E-32 T 06-07-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SMD11_RS18635 d5b5a2a5c4e5dd5d8a1f296eb9405db8 407 SUPERFAMILY SSF89392 118 288 2.71E-14 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX SMD11_RS18635 d5b5a2a5c4e5dd5d8a1f296eb9405db8 407 Gene3D G3DSA:2.50.20.10 123 288 1.4E-19 T 06-07-2017 SMD11_RS01790 0657f778630a0994a0894eb322f595e6 1124 SUPERFAMILY SSF48371 866 943 3.17E-5 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 SMD11_RS01790 0657f778630a0994a0894eb322f595e6 1124 SUPERFAMILY SSF48371 695 765 3.17E-5 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 SMD11_RS01790 0657f778630a0994a0894eb322f595e6 1124 SUPERFAMILY SSF48371 389 528 3.17E-5 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 SMD11_RS01790 0657f778630a0994a0894eb322f595e6 1124 SUPERFAMILY SSF48371 1092 1116 3.17E-5 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 SMD11_RS19080 f09d28a556a0320fe6ae1ad546434547 312 TIGRFAM TIGR00271 TIGR00271: uncharacterized hydrophobic domain 112 295 7.3E-53 T 06-07-2017 SMD11_RS19080 f09d28a556a0320fe6ae1ad546434547 312 Pfam PF04087 Domain of unknown function (DUF389) 145 288 1.1E-28 T 06-07-2017 IPR005240 Protein of unknown function DUF389 SMD11_RS07335 28f667b6d280d548d0c1282944a4c2be 354 Pfam PF02687 FtsX-like permease family 239 346 1.1E-9 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 SMD11_RS07530 f4ed8a3687294e3fcac137990cdd0684 425 Pfam PF02653 Branched-chain amino acid transport system / permease component 78 409 9.7E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD11_RS13325 d4f595470c91df0c3880b455f13a268c 440 Pfam PF04024 PspC domain 27 81 6.7E-14 T 06-07-2017 IPR007168 Phage shock protein, PspC, N-terminal SMD11_RS05415 81027471861eaf6097e41a6455d9e2fd 232 SUPERFAMILY SSF54427 99 229 1.16E-34 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS05415 81027471861eaf6097e41a6455d9e2fd 232 Pfam PF07366 SnoaL-like polyketide cyclase 102 227 1.1E-32 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain SMD11_RS05415 81027471861eaf6097e41a6455d9e2fd 232 Gene3D G3DSA:3.10.450.50 99 231 1.0E-41 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS01490 b685e4567faa27313effc125ddb0db9a 149 Pfam PF03413 Peptidase propeptide and YPEB domain 76 130 8.5E-11 T 06-07-2017 IPR025711 PepSY domain SMD11_RS21240 ef4f518c49c67df7a23f0706e7cd474c 429 Pfam PF02378 Phosphotransferase system, EIIC 35 352 1.6E-73 T 06-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SMD11_RS33210 d2a030c64de3fa90ac1e1affc35668dc 322 Pfam PF01636 Phosphotransferase enzyme family 24 231 3.1E-13 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase SMD11_RS33210 d2a030c64de3fa90ac1e1affc35668dc 322 Gene3D G3DSA:3.90.1200.10 102 250 2.2E-10 T 06-07-2017 SMD11_RS33210 d2a030c64de3fa90ac1e1affc35668dc 322 SUPERFAMILY SSF56112 16 311 6.85E-16 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS10190 0884d301f8e83de6f01f8219c979b2b8 65 Pfam PF04149 Domain of unknown function (DUF397) 5 54 1.1E-10 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS05125 ba1186be5bf1db4de14a241ed2f218c7 97 Pfam PF09851 Short C-terminal domain 62 87 5.3E-10 T 06-07-2017 IPR018649 SHOCT domain SMD11_RS04625 e785424a8af2e4fda74b4b0cb8990c95 284 Pfam PF00487 Fatty acid desaturase 26 245 1.5E-18 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 SMD11_RS04625 e785424a8af2e4fda74b4b0cb8990c95 284 PRINTS PR00075 Fatty acid desaturase family 1 signature 81 110 6.3E-11 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD11_RS04625 e785424a8af2e4fda74b4b0cb8990c95 284 PRINTS PR00075 Fatty acid desaturase family 1 signature 224 238 6.3E-11 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD11_RS04625 e785424a8af2e4fda74b4b0cb8990c95 284 PRINTS PR00075 Fatty acid desaturase family 1 signature 21 43 6.3E-11 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD11_RS04625 e785424a8af2e4fda74b4b0cb8990c95 284 PRINTS PR00075 Fatty acid desaturase family 1 signature 44 64 6.3E-11 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 SMD11_RS16620 19b97b2d06f4755c17ecec640b34ce79 456 Pfam PF07907 YibE/F-like protein 193 430 1.0E-72 T 06-07-2017 IPR012507 YibE/F-like SMD11_RS16475 eedf02f117ec4bfc3ede6083272c3b48 316 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 42 292 5.9E-65 T 06-07-2017 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 SMD11_RS16475 eedf02f117ec4bfc3ede6083272c3b48 316 SUPERFAMILY SSF56112 26 293 1.04E-21 T 06-07-2017 IPR011009 Protein kinase-like domain SMD11_RS16480 3bc932783d7f06a3a4debd6b7cd7f8aa 239 Pfam PF12679 ABC-2 family transporter protein 55 169 9.6E-12 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 SMD11_RS10955 75dfafed7e110adb0cced4e5e9418c23 136 Pfam PF05331 Protein of unknown function (DUF742) 9 136 1.8E-26 T 06-07-2017 IPR007995 Protein of unknown function DUF742 SMD11_RS09685 825c82548f68c631bbf4d4d751d5b6cf 262 Pfam PF00188 Cysteine-rich secretory protein family 145 260 5.3E-21 T 06-07-2017 IPR014044 CAP domain SMD11_RS09685 825c82548f68c631bbf4d4d751d5b6cf 262 SUPERFAMILY SSF55797 142 261 8.11E-25 T 06-07-2017 IPR014044 CAP domain SMD11_RS09685 825c82548f68c631bbf4d4d751d5b6cf 262 Gene3D G3DSA:3.40.33.10 142 259 3.3E-13 T 06-07-2017 IPR014044 CAP domain SMD11_RS32245 5a671afeac735bb9be380d75dcf73694 235 Gene3D G3DSA:3.40.50.1820 4 110 1.4E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32245 5a671afeac735bb9be380d75dcf73694 235 Gene3D G3DSA:3.40.50.1820 163 231 1.4E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32245 5a671afeac735bb9be380d75dcf73694 235 SUPERFAMILY SSF53474 3 227 2.46E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS32245 5a671afeac735bb9be380d75dcf73694 235 Pfam PF00975 Thioesterase domain 5 216 4.0E-31 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 SMD11_RS01400 190fac1819478f6b90a18ee867b2bee1 135 Pfam PF03995 Peptidase inhibitor family I36 27 96 2.7E-19 T 06-07-2017 SMD11_RS02815 456c612fbac96331202185ac3e025ffe 164 ProDom PD034336 YITP MEMBRANE YVAW TRANSMEMBRANE 19 144 2.0E-16 T 06-07-2017 IPR023902 Sporulation delaying protein SdpA SMD11_RS02815 456c612fbac96331202185ac3e025ffe 164 TIGRFAM TIGR04034 export_SdpA: antimicrobial peptide system protein, SdpA family 16 159 4.6E-37 T 06-07-2017 IPR023902 Sporulation delaying protein SdpA SMD11_RS11305 34da75e707970a9561b8952194db5b23 173 Pfam PF10756 Bacterial PH domain 80 112 9.6E-8 T 06-07-2017 IPR019692 Protein of unknown function DUF2581 SMD11_RS10890 19d904b0b1c09ceaae2198a955db8951 293 SMART SM01016 4 92 7.3E-20 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD11_RS10890 19d904b0b1c09ceaae2198a955db8951 293 Gene3D G3DSA:1.10.730.10 158 292 2.7E-22 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS10890 19d904b0b1c09ceaae2198a955db8951 293 Pfam PF05746 DALR anticodon binding domain 163 292 8.2E-17 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SMD11_RS10890 19d904b0b1c09ceaae2198a955db8951 293 SUPERFAMILY SSF55190 9 105 7.72E-14 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD11_RS10890 19d904b0b1c09ceaae2198a955db8951 293 SMART SM00836 163 293 1.5E-15 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SMD11_RS10890 19d904b0b1c09ceaae2198a955db8951 293 Gene3D G3DSA:3.30.1360.70 3 108 4.8E-21 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD11_RS10890 19d904b0b1c09ceaae2198a955db8951 293 SUPERFAMILY SSF47323 157 292 3.79E-16 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SMD11_RS10890 19d904b0b1c09ceaae2198a955db8951 293 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 23 92 5.2E-14 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SMD11_RS13880 a7d970c76c8356bcb74face88cec696b 88 Pfam PF13223 Protein of unknown function (DUF4031) 4 76 3.8E-30 T 06-07-2017 IPR025109 Domain of unknown function DUF4031 SMD11_RS30925 67a1329ef8865c2756c85a95a1491207 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 47 316 2.0E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD11_RS05830 60e70f70fa0e2483e4b73703ad10c60c 380 Pfam PF06889 Protein of unknown function (DUF1266) 189 379 6.8E-31 T 06-07-2017 IPR009677 Protein of unknown function DUF1266 SMD11_RS33400 3b64b52b290323f103f2d699c8d91853 224 Pfam PF09836 Putative DNA-binding domain 10 104 3.5E-20 T 06-07-2017 IPR018640 Putative DNA-binding domain, bacteria SMD11_RS03060 2029aae13e20e2536417a21ae9c25a28 143 Gene3D G3DSA:3.10.180.10 10 134 2.5E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS03060 2029aae13e20e2536417a21ae9c25a28 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 131 2.7E-8 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS03060 2029aae13e20e2536417a21ae9c25a28 143 SUPERFAMILY SSF54593 10 138 1.13E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS25825 a4dc7fb012378fa798af6c648cee1f8c 331 Pfam PF02616 Segregation and condensation protein ScpA 77 297 3.9E-49 T 06-07-2017 IPR003768 Segregation and condensation protein A SMD11_RS11075 ed267092479fd377d52bb72844699fb0 471 SUPERFAMILY SSF51445 177 363 3.28E-48 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS11075 ed267092479fd377d52bb72844699fb0 471 SUPERFAMILY SSF51445 36 143 3.28E-48 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily SMD11_RS11075 ed267092479fd377d52bb72844699fb0 471 Gene3D G3DSA:3.20.20.80 177 367 8.1E-50 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS11075 ed267092479fd377d52bb72844699fb0 471 Gene3D G3DSA:3.20.20.80 38 131 8.1E-50 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SMD11_RS11075 ed267092479fd377d52bb72844699fb0 471 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 67 359 4.0E-28 T 06-07-2017 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 SMD11_RS10775 7cf57ac106d911249a12a8ae9d1b5b39 149 Pfam PF10739 Protein of unknown function (DUF2550) 12 143 4.2E-43 T 06-07-2017 IPR019675 Protein of unknown function DUF2550 SMD11_RS03575 8197c7989b3045eabb62f05e87d6576d 538 Pfam PF12222 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A 45 370 4.6E-71 T 06-07-2017 IPR021102 Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase A SMD11_RS28830 1f8f29003f455a0a748835618935bbd8 278 Hamap MF_01384 Urease accessory protein UreD [ureD]. 11 266 19.098 T 06-07-2017 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 SMD11_RS28830 1f8f29003f455a0a748835618935bbd8 278 Pfam PF01774 UreD urease accessory protein 64 228 2.1E-25 T 06-07-2017 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 SMD11_RS05660 11193ef2d2c9efab289c3fdf08f63571 170 Gene3D G3DSA:2.30.110.10 4 161 3.3E-50 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS05660 11193ef2d2c9efab289c3fdf08f63571 170 Pfam PF01613 Flavin reductase like domain 13 157 1.1E-34 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS05660 11193ef2d2c9efab289c3fdf08f63571 170 SUPERFAMILY SSF50475 3 158 1.04E-43 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 SMD11_RS05660 11193ef2d2c9efab289c3fdf08f63571 170 SMART SM00903 12 158 3.0E-48 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 SMD11_RS04805 c0aa20ca59ee564575a6788acacd2096 280 Gene3D G3DSA:1.10.3720.10 84 269 1.9E-10 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS04805 c0aa20ca59ee564575a6788acacd2096 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 270 7.3E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS04805 c0aa20ca59ee564575a6788acacd2096 280 SUPERFAMILY SSF161098 85 261 1.44E-8 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS12190 f72a33a6f1c3f1f8f97613aec6b437d0 224 SUPERFAMILY SSF53335 23 202 2.09E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS12190 f72a33a6f1c3f1f8f97613aec6b437d0 224 Pfam PF13649 Methyltransferase domain 60 152 4.4E-18 T 06-07-2017 SMD11_RS12190 f72a33a6f1c3f1f8f97613aec6b437d0 224 Gene3D G3DSA:3.40.50.150 22 196 9.6E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS18395 6c660598c361c0baaead8ee29184b2d5 385 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 116 383 2.5E-76 T 06-07-2017 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 SMD11_RS18395 6c660598c361c0baaead8ee29184b2d5 385 Pfam PF01578 Cytochrome C assembly protein 140 376 3.4E-44 T 06-07-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 SMD11_RS18370 e3eb0e300e5b23071702cd1c1470e874 232 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 15 202 1.9E-33 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS18370 e3eb0e300e5b23071702cd1c1470e874 232 SUPERFAMILY SSF53254 13 204 5.74E-36 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS18370 e3eb0e300e5b23071702cd1c1470e874 232 SMART SM00855 14 166 4.6E-16 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 SMD11_RS18370 e3eb0e300e5b23071702cd1c1470e874 232 Gene3D G3DSA:3.40.50.1240 15 201 9.7E-29 T 06-07-2017 IPR029033 Histidine phosphatase superfamily SMD11_RS12260 a2ac2967612a15417fdbbb472588b930 348 SUPERFAMILY SSF51430 20 335 4.85E-87 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS12260 a2ac2967612a15417fdbbb472588b930 348 Pfam PF00248 Aldo/keto reductase family 35 333 1.2E-65 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS12260 a2ac2967612a15417fdbbb472588b930 348 Gene3D G3DSA:3.20.20.100 20 335 2.3E-84 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS03275 af77df00c6eee6863e2f3e6d1163ce5e 130 SUPERFAMILY SSF54593 10 121 1.48E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS03275 af77df00c6eee6863e2f3e6d1163ce5e 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 114 1.5E-11 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS03275 af77df00c6eee6863e2f3e6d1163ce5e 130 Gene3D G3DSA:3.10.180.10 10 125 1.3E-25 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS14350 dd9cc1dd855bdb39f4baaca529bd6763 401 Pfam PF13646 HEAT repeats 266 351 2.1E-10 T 06-07-2017 SMD11_RS14350 dd9cc1dd855bdb39f4baaca529bd6763 401 Gene3D G3DSA:1.25.40.20 29 90 4.5E-7 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain SMD11_RS14350 dd9cc1dd855bdb39f4baaca529bd6763 401 Gene3D G3DSA:1.25.10.10 222 361 9.4E-15 T 06-07-2017 IPR011989 Armadillo-like helical SMD11_RS14350 dd9cc1dd855bdb39f4baaca529bd6763 401 SUPERFAMILY SSF48371 170 364 6.64E-16 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 SMD11_RS14350 dd9cc1dd855bdb39f4baaca529bd6763 401 SUPERFAMILY SSF48403 28 88 8.39E-8 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain SMD11_RS25390 b0d63c22eb99e51ae2e1065a06f7ebcc 327 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 17 297 2.1E-53 T 06-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 SMD11_RS25390 b0d63c22eb99e51ae2e1065a06f7ebcc 327 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 315 93.392 T 06-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 SMD11_RS25390 b0d63c22eb99e51ae2e1065a06f7ebcc 327 Pfam PF03186 CobD/Cbib protein 13 290 7.0E-90 T 06-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 SMD11_RS31950 434660e870e252c0a9dfe3d9d4f33169 134 Pfam PF06078 Bacterial protein of unknown function (DUF937) 6 119 8.8E-11 T 06-07-2017 IPR009282 Protein of unknown function DUF937 SMD11_RS31950 434660e870e252c0a9dfe3d9d4f33169 134 SUPERFAMILY SSF140804 28 128 3.01E-25 T 06-07-2017 IPR027405 YidB-like SMD11_RS31950 434660e870e252c0a9dfe3d9d4f33169 134 Gene3D G3DSA:1.10.10.690 5 126 1.7E-31 T 06-07-2017 IPR027405 YidB-like SMD11_RS24055 f705d10d397f0e1e783eaebdcc5f00bd 173 Pfam PF14024 Protein of unknown function (DUF4240) 2 129 3.5E-44 T 06-07-2017 IPR025334 Domain of unknown function (DUF4240 SMD11_RS20905 79977373f2c4cf5fc05ef0bfc74f2d5f 457 Gene3D G3DSA:3.40.190.10 189 381 1.4E-23 T 06-07-2017 SMD11_RS20905 79977373f2c4cf5fc05ef0bfc74f2d5f 457 Gene3D G3DSA:3.40.190.10 67 188 5.0E-21 T 06-07-2017 SMD11_RS20905 79977373f2c4cf5fc05ef0bfc74f2d5f 457 Pfam PF01547 Bacterial extracellular solute-binding protein 72 366 3.9E-19 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 SMD11_RS20905 79977373f2c4cf5fc05ef0bfc74f2d5f 457 SUPERFAMILY SSF53850 59 450 2.43E-48 T 06-07-2017 SMD11_RS23090 72acd98c9cd894b190d254c56e30f568 240 Pfam PF00005 ABC transporter 32 172 5.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS23090 72acd98c9cd894b190d254c56e30f568 240 SMART SM00382 41 222 2.4E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS23090 72acd98c9cd894b190d254c56e30f568 240 SUPERFAMILY SSF52540 15 236 1.09E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS23090 72acd98c9cd894b190d254c56e30f568 240 Gene3D G3DSA:3.40.50.300 10 235 2.4E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS08995 274feaf5c43b85c51e13ccd947c614fd 179 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 20 161 1.7E-36 T 06-07-2017 IPR008136 CinA, C-terminal SMD11_RS08995 274feaf5c43b85c51e13ccd947c614fd 179 SUPERFAMILY SSF142433 9 164 9.68E-45 T 06-07-2017 IPR008136 CinA, C-terminal SMD11_RS08995 274feaf5c43b85c51e13ccd947c614fd 179 Gene3D G3DSA:3.90.950.20 9 166 2.0E-53 T 06-07-2017 IPR008136 CinA, C-terminal SMD11_RS08995 274feaf5c43b85c51e13ccd947c614fd 179 Pfam PF02464 Competence-damaged protein 13 162 3.8E-48 T 06-07-2017 IPR008136 CinA, C-terminal SMD11_RS27550 a501bdcc9dc2f25cf179483986600db5 197 SUPERFAMILY SSF52540 26 181 7.92E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS27550 a501bdcc9dc2f25cf179483986600db5 197 Gene3D G3DSA:3.40.50.300 23 183 4.9E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS14420 290f49d923269ea223a2c29332f23f0a 122 Gene3D G3DSA:3.40.1260.10 4 113 5.8E-17 T 06-07-2017 IPR027396 DsrEFH-like SMD11_RS14420 290f49d923269ea223a2c29332f23f0a 122 Pfam PF02635 DsrE/DsrF-like family 4 109 1.8E-9 T 06-07-2017 IPR003787 Sulphur relay, DsrE/F-like protein SMD11_RS14420 290f49d923269ea223a2c29332f23f0a 122 SUPERFAMILY SSF75169 4 115 1.01E-18 T 06-07-2017 IPR027396 DsrEFH-like SMD11_RS22950 368d12b15945d7bc89b367a8cd7ca21b 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 284 6.4E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS22950 368d12b15945d7bc89b367a8cd7ca21b 291 SUPERFAMILY SSF161098 21 288 4.58E-60 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS22950 368d12b15945d7bc89b367a8cd7ca21b 291 Gene3D G3DSA:1.10.3720.10 20 278 5.1E-57 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS01605 b6762b1b3ac71cd794861fc89dba086f 493 Gene3D G3DSA:1.50.10.50 58 482 1.6E-102 T 06-07-2017 IPR001382 Glycoside hydrolase family 47 GO:0004571|GO:0005509|GO:0016020 KEGG: 00510+3.2.1.113|KEGG: 00513+3.2.1.113 SMD11_RS01605 b6762b1b3ac71cd794861fc89dba086f 493 SUPERFAMILY SSF48225 60 482 9.29E-105 T 06-07-2017 IPR001382 Glycoside hydrolase family 47 GO:0004571|GO:0005509|GO:0016020 KEGG: 00510+3.2.1.113|KEGG: 00513+3.2.1.113 SMD11_RS01605 b6762b1b3ac71cd794861fc89dba086f 493 PRINTS PR00747 Glycosyl hydrolase family 47 signature 386 410 6.3E-40 T 06-07-2017 IPR001382 Glycoside hydrolase family 47 GO:0004571|GO:0005509|GO:0016020 KEGG: 00510+3.2.1.113|KEGG: 00513+3.2.1.113 SMD11_RS01605 b6762b1b3ac71cd794861fc89dba086f 493 PRINTS PR00747 Glycosyl hydrolase family 47 signature 447 467 6.3E-40 T 06-07-2017 IPR001382 Glycoside hydrolase family 47 GO:0004571|GO:0005509|GO:0016020 KEGG: 00510+3.2.1.113|KEGG: 00513+3.2.1.113 SMD11_RS01605 b6762b1b3ac71cd794861fc89dba086f 493 PRINTS PR00747 Glycosyl hydrolase family 47 signature 106 120 6.3E-40 T 06-07-2017 IPR001382 Glycoside hydrolase family 47 GO:0004571|GO:0005509|GO:0016020 KEGG: 00510+3.2.1.113|KEGG: 00513+3.2.1.113 SMD11_RS01605 b6762b1b3ac71cd794861fc89dba086f 493 PRINTS PR00747 Glycosyl hydrolase family 47 signature 183 202 6.3E-40 T 06-07-2017 IPR001382 Glycoside hydrolase family 47 GO:0004571|GO:0005509|GO:0016020 KEGG: 00510+3.2.1.113|KEGG: 00513+3.2.1.113 SMD11_RS01605 b6762b1b3ac71cd794861fc89dba086f 493 PRINTS PR00747 Glycosyl hydrolase family 47 signature 70 90 6.3E-40 T 06-07-2017 IPR001382 Glycoside hydrolase family 47 GO:0004571|GO:0005509|GO:0016020 KEGG: 00510+3.2.1.113|KEGG: 00513+3.2.1.113 SMD11_RS01605 b6762b1b3ac71cd794861fc89dba086f 493 PRINTS PR00747 Glycosyl hydrolase family 47 signature 143 161 6.3E-40 T 06-07-2017 IPR001382 Glycoside hydrolase family 47 GO:0004571|GO:0005509|GO:0016020 KEGG: 00510+3.2.1.113|KEGG: 00513+3.2.1.113 SMD11_RS01605 b6762b1b3ac71cd794861fc89dba086f 493 PRINTS PR00747 Glycosyl hydrolase family 47 signature 273 290 6.3E-40 T 06-07-2017 IPR001382 Glycoside hydrolase family 47 GO:0004571|GO:0005509|GO:0016020 KEGG: 00510+3.2.1.113|KEGG: 00513+3.2.1.113 SMD11_RS01605 b6762b1b3ac71cd794861fc89dba086f 493 Pfam PF01532 Glycosyl hydrolase family 47 71 481 1.8E-86 T 06-07-2017 IPR001382 Glycoside hydrolase family 47 GO:0004571|GO:0005509|GO:0016020 KEGG: 00510+3.2.1.113|KEGG: 00513+3.2.1.113 SMD11_RS22225 861e6b53cf1f86009810b25414905b24 475 PIRSF PIRSF006060 3 474 1.6E-61 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS22225 861e6b53cf1f86009810b25414905b24 475 ProSitePatterns PS00218 Amino acid permeases signature. 58 88 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SMD11_RS22225 861e6b53cf1f86009810b25414905b24 475 Pfam PF00324 Amino acid permease 33 461 7.6E-98 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMD11_RS26090 0119f0dbd5e535fc83bd9238acf24f74 576 Pfam PF04183 IucA / IucC family 136 350 7.9E-48 T 06-07-2017 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 SMD11_RS26090 0119f0dbd5e535fc83bd9238acf24f74 576 Pfam PF06276 Ferric iron reductase FhuF-like transporter 378 536 3.5E-34 T 06-07-2017 IPR022770 Ferric iron reductase FhuF domain SMD11_RS22875 5d470ddcfc032255b0c225ff0602e743 296 SUPERFAMILY SSF81345 7 259 4.05E-34 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS22875 5d470ddcfc032255b0c225ff0602e743 296 Gene3D G3DSA:1.10.3470.10 41 259 7.3E-8 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS22875 5d470ddcfc032255b0c225ff0602e743 296 Pfam PF00950 ABC 3 transport family 7 260 9.6E-66 T 06-07-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 SMD11_RS19545 8be7bc417404ec33d4a71cd84163aa5d 67 Pfam PF04149 Domain of unknown function (DUF397) 9 60 9.6E-24 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS17185 c48c41a3bc89eadc5d8637939d9987a8 297 Pfam PF12804 MobA-like NTP transferase domain 6 152 8.7E-30 T 06-07-2017 IPR025877 MobA-like NTP transferase SMD11_RS17185 c48c41a3bc89eadc5d8637939d9987a8 297 Gene3D G3DSA:3.90.550.10 3 195 6.0E-41 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS17185 c48c41a3bc89eadc5d8637939d9987a8 297 SUPERFAMILY SSF53448 4 185 8.88E-29 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS09500 1b8c2da048ff1b66e99d5408281f8c56 367 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 321 347 - T 06-07-2017 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 SMD11_RS09500 1b8c2da048ff1b66e99d5408281f8c56 367 Pfam PF01148 Cytidylyltransferase family 107 363 8.8E-64 T 06-07-2017 SMD11_RS29645 d3b1d2a2dded9afa4ab22dbbd1c3cc46 645 Gene3D G3DSA:3.90.550.10 262 436 5.3E-12 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS29645 d3b1d2a2dded9afa4ab22dbbd1c3cc46 645 SUPERFAMILY SSF53448 198 448 4.39E-34 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS29645 d3b1d2a2dded9afa4ab22dbbd1c3cc46 645 Pfam PF13506 Glycosyl transferase family 21 252 420 3.6E-19 T 06-07-2017 IPR025993 Ceramide glucosyltransferase GO:0016757 KEGG: 00600+2.4.1.80|MetaCyc: PWY-5129|Reactome: R-HSA-1660662 SMD11_RS01850 889983c5bcaf2b02f9e8026f640e8d57 289 SUPERFAMILY SSF55681 26 273 6.91E-21 T 06-07-2017 SMD11_RS01850 889983c5bcaf2b02f9e8026f640e8d57 289 Gene3D G3DSA:3.30.930.10 25 274 3.1E-11 T 06-07-2017 SMD11_RS15840 416114b01bf22e24c5233c836a17a29f 450 Gene3D G3DSA:1.25.40.10 210 407 2.2E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS18455 ff3258b57ffe78beec86c0abfb398e3a 208 Gene3D G3DSA:1.10.357.10 2 196 4.1E-43 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS18455 ff3258b57ffe78beec86c0abfb398e3a 208 SUPERFAMILY SSF46689 2 79 7.18E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS18455 ff3258b57ffe78beec86c0abfb398e3a 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 4.9E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS18455 ff3258b57ffe78beec86c0abfb398e3a 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS18455 ff3258b57ffe78beec86c0abfb398e3a 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS18455 ff3258b57ffe78beec86c0abfb398e3a 208 SUPERFAMILY SSF48498 81 193 1.37E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal SMD11_RS08330 9cc2d6b44128adfd6cf7f99d9ad39030 683 Pfam PF13520 Amino acid permease 58 464 4.4E-34 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS26045 53f2769a4ebb391de56dfa76c11d61b9 290 SUPERFAMILY SSF53474 51 235 3.81E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS26045 53f2769a4ebb391de56dfa76c11d61b9 290 Pfam PF01674 Lipase (class 2) 55 229 7.2E-17 T 06-07-2017 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 SMD11_RS26045 53f2769a4ebb391de56dfa76c11d61b9 290 Gene3D G3DSA:3.40.50.1820 32 286 1.9E-76 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS08665 85588a746abbb2f1b49b3c5369516e77 313 PIRSF PIRSF035042 1 304 3.1E-66 T 06-07-2017 IPR010350 Thioredoxin-like ferredoxin, bacteria SMD11_RS08665 85588a746abbb2f1b49b3c5369516e77 313 Gene3D G3DSA:3.40.30.10 131 217 3.4E-11 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS08665 85588a746abbb2f1b49b3c5369516e77 313 SUPERFAMILY SSF52833 130 219 7.04E-13 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS08665 85588a746abbb2f1b49b3c5369516e77 313 Pfam PF06999 Sucrase/ferredoxin-like 15 214 4.5E-21 T 06-07-2017 IPR009737 Thioredoxin-like ferredoxin SMD11_RS08545 ba075aff9ac6c586d5aff21caeb7851b 98 Pfam PF13834 Domain of unknown function (DUF4193) 1 97 3.2E-45 T 06-07-2017 IPR025242 Protein of unknown function DUF4193 SMD11_RS20205 30d8a97a63225709919fcb874a85a5c6 914 Pfam PF14435 SUKH-4 immunity protein 731 908 1.7E-42 T 06-07-2017 IPR025851 SUKH-4 immunity protein SMD11_RS20205 30d8a97a63225709919fcb874a85a5c6 914 Pfam PF14440 Xanthomonas XOO_2897-like deaminase 592 691 9.8E-34 T 06-07-2017 IPR032722 Deaminase, Xanthomonas XOO_2897-like SMD11_RS08735 be7feb39ca4c2c0515249d70985a3648 459 Pfam PF13830 Domain of unknown function (DUF4192) 30 372 2.1E-94 T 06-07-2017 IPR025447 Protein of unknown function DUF4192 SMD11_RS08840 d175d89ba9704d6d40829df34e06649b 395 Gene3D G3DSA:2.40.10.10 161 268 4.6E-7 T 06-07-2017 SMD11_RS08840 d175d89ba9704d6d40829df34e06649b 395 SUPERFAMILY SSF50494 141 228 7.73E-17 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS08840 d175d89ba9704d6d40829df34e06649b 395 SUPERFAMILY SSF50494 256 357 7.73E-17 T 06-07-2017 IPR009003 Peptidase S1, PA clan SMD11_RS34350 5a1976375cb29616a95b836aaeb722c4 76 Gene3D G3DSA:1.10.1200.20 8 73 2.0E-7 T 06-07-2017 IPR023802 Colicin/pyocin immunity protein domain GO:0015643 SMD11_RS13750 9d089917d9b30ceff01f4cb10ff50604 187 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 185 21.233 T 06-07-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 SMD11_RS13750 9d089917d9b30ceff01f4cb10ff50604 187 SUPERFAMILY SSF55144 1 186 1.92E-35 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase SMD11_RS13750 9d089917d9b30ceff01f4cb10ff50604 187 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 183 3.8E-27 T 06-07-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 SMD11_RS13750 9d089917d9b30ceff01f4cb10ff50604 187 Pfam PF02834 LigT like Phosphoesterase 8 83 1.4E-11 T 06-07-2017 IPR014051 Phosphoesterase, HXTX SMD11_RS13750 9d089917d9b30ceff01f4cb10ff50604 187 Pfam PF02834 LigT like Phosphoesterase 97 170 3.2E-8 T 06-07-2017 IPR014051 Phosphoesterase, HXTX SMD11_RS13750 9d089917d9b30ceff01f4cb10ff50604 187 Gene3D G3DSA:3.90.1140.10 1 186 9.7E-49 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase SMD11_RS09405 a7299c9948bb6a54328bd0f0a65458ce 462 Pfam PF13649 Methyltransferase domain 248 344 6.0E-21 T 06-07-2017 SMD11_RS09405 a7299c9948bb6a54328bd0f0a65458ce 462 Pfam PF13785 Domain of unknown function (DUF4178) 47 178 4.2E-12 T 06-07-2017 IPR025235 Domain of unknown function DUF4178 SMD11_RS09405 a7299c9948bb6a54328bd0f0a65458ce 462 SUPERFAMILY SSF53335 205 445 6.69E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS09405 a7299c9948bb6a54328bd0f0a65458ce 462 Gene3D G3DSA:3.40.50.150 411 440 2.8E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS09405 a7299c9948bb6a54328bd0f0a65458ce 462 Gene3D G3DSA:3.40.50.150 206 379 2.8E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS26230 e78f0ed2b05af880398936e963e5705e 437 SUPERFAMILY SSF53474 255 367 1.15E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS26230 e78f0ed2b05af880398936e963e5705e 437 Gene3D G3DSA:3.40.50.1820 253 339 5.4E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS15315 9f51bcf116e999cc36d02c70490cd6c1 114 Pfam PF07811 TadE-like protein 7 49 1.8E-6 T 06-07-2017 IPR012495 TadE-like SMD11_RS11925 187a7fae68de2492f9dc73cb03474153 317 Pfam PF00005 ABC transporter 37 171 4.7E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SMD11_RS11925 187a7fae68de2492f9dc73cb03474153 317 SMART SM00382 44 220 2.8E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain SMD11_RS11925 187a7fae68de2492f9dc73cb03474153 317 Gene3D G3DSA:3.40.50.300 14 237 1.4E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS11925 187a7fae68de2492f9dc73cb03474153 317 SUPERFAMILY SSF52540 18 236 1.31E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS01195 13d225357fec1f9ae5a621bc6b944efa 410 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 20 371 7.6E-107 T 06-07-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 SMD11_RS01195 13d225357fec1f9ae5a621bc6b944efa 410 Gene3D G3DSA:3.40.50.1820 262 373 1.2E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01195 13d225357fec1f9ae5a621bc6b944efa 410 Gene3D G3DSA:3.40.50.1820 32 230 1.2E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01195 13d225357fec1f9ae5a621bc6b944efa 410 SUPERFAMILY SSF53474 21 373 1.36E-74 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS01195 13d225357fec1f9ae5a621bc6b944efa 410 PIRSF PIRSF000443 9 378 5.5E-108 T 06-07-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 SMD11_RS01195 13d225357fec1f9ae5a621bc6b944efa 410 Pfam PF00561 alpha/beta hydrolase fold 50 359 2.9E-27 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 SMD11_RS23875 adaca1349783babd9e0e860537555ff2 303 Pfam PF14378 PAP2 superfamily 86 265 4.9E-46 T 06-07-2017 IPR026841 Inositolphosphotransferase Aur1/Ipt1 SMD11_RS18385 60d4f720ac6c692c8c09850686b0f807 245 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 18 224 9.2E-54 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 SMD11_RS19110 2016cf404f589e084b1a9d84529af7e5 76 Pfam PF04149 Domain of unknown function (DUF397) 26 64 1.3E-5 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS12320 253ee1bbff1e801ac2e6fdd830fef998 295 Pfam PF00482 Type II secretion system (T2SS), protein F 152 278 2.7E-22 T 06-07-2017 IPR018076 Type II secretion system F domain SMD11_RS08010 84d6a356c11aba41a250cfabff6c9d55 403 Pfam PF01757 Acyltransferase family 9 352 5.7E-34 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 SMD11_RS27570 cff5339b2ca256a8d5cf8604abc34ef8 142 Pfam PF05610 Protein of unknown function (DUF779) 30 129 2.1E-46 T 06-07-2017 IPR008497 Protein of unknown function DUF779 SMD11_RS27570 cff5339b2ca256a8d5cf8604abc34ef8 142 PIRSF PIRSF009151 7 142 2.3E-59 T 06-07-2017 IPR008497 Protein of unknown function DUF779 SMD11_RS33115 f5be3dcccf89eda516e186c2bc6d9990 516 Pfam PF04984 Phage tail sheath protein 1 505 6.6E-90 T 06-07-2017 IPR007067 Tail sheath protein SMD11_RS13835 651de11d7e1e4e47140ae70a8b8eb42d 351 Gene3D G3DSA:1.10.3470.10 25 347 8.6E-86 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS13835 651de11d7e1e4e47140ae70a8b8eb42d 351 Pfam PF01032 FecCD transport family 38 344 5.2E-80 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SMD11_RS13835 651de11d7e1e4e47140ae70a8b8eb42d 351 SUPERFAMILY SSF81345 23 344 8.5E-69 T 06-07-2017 IPR029022 ABC transporter, BtuC-like SMD11_RS27680 db28222609e7c693b9ad4721ca17f887 316 Pfam PF10935 Protein of unknown function (DUF2637) 22 136 1.5E-7 T 06-07-2017 IPR021235 Protein of unknown function DUF2637 SMD11_RS30950 a882e8a7ee5bc996dd506e2f74121950 118 Pfam PF05656 Protein of unknown function (DUF805) 11 112 1.3E-32 T 06-07-2017 IPR008523 Protein of unknown function DUF805 GO:0016021 SMD11_RS23640 57b5996ad61ffdb1e36951da8ece9dc8 265 Pfam PF03883 Protein of unknown function (DUF328) 2 244 1.4E-38 T 06-07-2017 IPR005583 Peroxide stress protein YaaA SMD11_RS31030 fa26888cd7c5a4a5875600567ef771a0 551 Pfam PF13520 Amino acid permease 11 421 6.2E-43 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS32075 cd2193f179a26de49ea3fa6e52eea866 320 PRINTS PR00682 Isopenicillin N synthase signature 239 265 3.6E-7 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 SMD11_RS32075 cd2193f179a26de49ea3fa6e52eea866 320 PRINTS PR00682 Isopenicillin N synthase signature 29 46 3.6E-7 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 SMD11_RS32075 cd2193f179a26de49ea3fa6e52eea866 320 PRINTS PR00682 Isopenicillin N synthase signature 151 167 3.6E-7 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 SMD11_RS32075 cd2193f179a26de49ea3fa6e52eea866 320 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 6 114 1.5E-16 T 06-07-2017 IPR026992 Non-haem dioxygenase N-terminal domain SMD11_RS32075 cd2193f179a26de49ea3fa6e52eea866 320 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 194 266 7.6E-12 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 SMD11_RS32075 cd2193f179a26de49ea3fa6e52eea866 320 SUPERFAMILY SSF51197 2 316 4.05E-68 T 06-07-2017 SMD11_RS32075 cd2193f179a26de49ea3fa6e52eea866 320 Gene3D G3DSA:2.60.120.330 4 316 4.2E-73 T 06-07-2017 IPR027443 Isopenicillin N synthase-like SMD11_RS22610 fbb249d0bcb4a937d60c7a8dfd5b93da 276 Pfam PF11296 Protein of unknown function (DUF3097) 6 272 2.6E-126 T 06-07-2017 IPR021447 Protein of unknown function DUF3097 SMD11_RS21560 0ff7c50243fdf094c25e8fbf265202d8 406 Gene3D G3DSA:3.40.390.10 207 247 7.2E-5 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SMD11_RS21560 0ff7c50243fdf094c25e8fbf265202d8 406 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 70 334 7.3E-54 T 06-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 SMD11_RS20815 89ec4490195144e3d076bac9ab01a624 208 Pfam PF13302 Acetyltransferase (GNAT) domain 10 154 2.6E-34 T 06-07-2017 IPR000182 GNAT domain GO:0008080 SMD11_RS20815 89ec4490195144e3d076bac9ab01a624 208 Gene3D G3DSA:3.40.630.30 1 181 3.0E-53 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS20815 89ec4490195144e3d076bac9ab01a624 208 SUPERFAMILY SSF55729 1 177 8.11E-46 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase SMD11_RS33405 54e852a9ec22f139dc49ba8445b3a503 409 Pfam PF12902 Ferritin-like 26 240 2.2E-36 T 06-07-2017 SMD11_RS34140 2f69ed310ee9af4646117bb34c5a9e5e 113 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 53 85 2.5E-10 T 06-07-2017 IPR025161 Putative transposase IS4/IS5 family SMD11_RS11740 1abb62cf8aa237e218a2c75a7532716b 317 Pfam PF01936 NYN domain 45 191 1.2E-10 T 06-07-2017 IPR021139 NYN domain, limkain-b1-type SMD11_RS11740 1abb62cf8aa237e218a2c75a7532716b 317 Gene3D G3DSA:3.40.50.1010 41 187 3.0E-16 T 06-07-2017 IPR029060 PIN domain-like SMD11_RS19635 e8a84b0fc216d08007788ea7d372b740 166 Gene3D G3DSA:2.80.10.50 42 161 1.0E-9 T 06-07-2017 SMD11_RS19635 e8a84b0fc216d08007788ea7d372b740 166 SUPERFAMILY SSF50370 35 160 2.97E-11 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS02455 906f4525abb6e44f22c1f43a81798b4f 358 Pfam PF12671 Putative amidase domain 204 353 5.9E-35 T 06-07-2017 IPR024301 Putative amidase domain SMD11_RS13560 3ae6e6514ea8c5e5cd1f8bda9724f058 462 SUPERFAMILY SSF48452 353 422 4.93E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS13560 3ae6e6514ea8c5e5cd1f8bda9724f058 462 SUPERFAMILY SSF48452 225 255 4.93E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS13560 3ae6e6514ea8c5e5cd1f8bda9724f058 462 Gene3D G3DSA:1.25.40.10 349 421 4.6E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS13560 3ae6e6514ea8c5e5cd1f8bda9724f058 462 Gene3D G3DSA:1.25.40.10 226 249 4.6E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS07550 eaddf12527159c0f55c6d623e1a43982 132 Gene3D G3DSA:2.170.16.10 16 132 3.3E-17 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain SMD11_RS07550 eaddf12527159c0f55c6d623e1a43982 132 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 108 132 4.5E-6 T 06-07-2017 IPR030934 Intein C-terminal splicing region SMD11_RS07550 eaddf12527159c0f55c6d623e1a43982 132 SUPERFAMILY SSF51294 17 132 1.9E-14 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain SMD11_RS07550 eaddf12527159c0f55c6d623e1a43982 132 Pfam PF07591 Pretoxin HINT domain 17 132 1.8E-16 T 06-07-2017 SMD11_RS33780 4bbe71b40a9a6174c0df9f9454d92430 219 SMART SM00953 38 186 5.9E-12 T 06-07-2017 IPR014914 RES domain SMD11_RS33780 4bbe71b40a9a6174c0df9f9454d92430 219 Pfam PF08808 RES domain 24 188 1.5E-23 T 06-07-2017 IPR014914 RES domain SMD11_RS02575 f894a4e11e23a319778d34895576fb54 311 Gene3D G3DSA:3.30.2010.10 66 151 1.8E-16 T 06-07-2017 SMD11_RS02575 f894a4e11e23a319778d34895576fb54 311 Pfam PF01435 Peptidase family M48 71 303 1.8E-17 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SMD11_RS12315 58b2e370411b498f38908e726b374e7f 59 Pfam PF04964 Flp/Fap pilin component 10 50 5.0E-8 T 06-07-2017 IPR007047 Flp/Fap pilin component SMD11_RS10925 984ed1df518a3d41bb561d0219773c4a 317 SUPERFAMILY SSF47240 43 229 8.12E-13 T 06-07-2017 IPR009078 Ferritin-like superfamily SMD11_RS10925 984ed1df518a3d41bb561d0219773c4a 317 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 26 300 1.4E-101 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF SMD11_RS30125 ea64159d64f0c32b336c1c0660d462ca 467 SUPERFAMILY SSF53474 30 446 4.61E-92 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30125 ea64159d64f0c32b336c1c0660d462ca 467 Gene3D G3DSA:3.40.50.1820 25 448 3.8E-104 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS30125 ea64159d64f0c32b336c1c0660d462ca 467 PRINTS PR00724 Carboxypeptidase C serine protease (S10) family signature 413 426 1.6E-18 T 06-07-2017 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 SMD11_RS30125 ea64159d64f0c32b336c1c0660d462ca 467 PRINTS PR00724 Carboxypeptidase C serine protease (S10) family signature 162 187 1.6E-18 T 06-07-2017 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 SMD11_RS30125 ea64159d64f0c32b336c1c0660d462ca 467 PRINTS PR00724 Carboxypeptidase C serine protease (S10) family signature 115 127 1.6E-18 T 06-07-2017 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 SMD11_RS30125 ea64159d64f0c32b336c1c0660d462ca 467 PRINTS PR00724 Carboxypeptidase C serine protease (S10) family signature 128 138 1.6E-18 T 06-07-2017 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 SMD11_RS30125 ea64159d64f0c32b336c1c0660d462ca 467 ProSitePatterns PS00131 Serine carboxypeptidases, serine active site. 176 183 - T 06-07-2017 IPR018202 Serine carboxypeptidase, serine active site SMD11_RS30125 ea64159d64f0c32b336c1c0660d462ca 467 Pfam PF00450 Serine carboxypeptidase 27 442 7.2E-87 T 06-07-2017 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 SMD11_RS30125 ea64159d64f0c32b336c1c0660d462ca 467 ProSitePatterns PS00560 Serine carboxypeptidases, histidine active site. 413 430 - T 06-07-2017 IPR033124 Serine carboxypeptidases, histidine active site Reactome: R-HSA-1660662|Reactome: R-HSA-2132295|Reactome: R-HSA-4085001 SMD11_RS00115 83e2c43f0c1539682769e6a01d994ca1 595 SUPERFAMILY SSF89372 300 421 2.48E-9 T 06-07-2017 SMD11_RS00115 83e2c43f0c1539682769e6a01d994ca1 595 Gene3D G3DSA:2.120.10.10 358 501 2.4E-6 T 06-07-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 SMD11_RS00115 83e2c43f0c1539682769e6a01d994ca1 595 SUPERFAMILY SSF89372 396 592 7.32E-19 T 06-07-2017 SMD11_RS25345 c116f5e0b7724f4c2f3549d206fd1279 358 Pfam PF01758 Sodium Bile acid symporter family 69 244 2.4E-40 T 06-07-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 SMD11_RS07100 e5b4e53e63daa1016f558df8e669c100 486 Pfam PF00860 Permease family 45 435 2.5E-33 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD11_RS03455 2dabf396b37795fd7cd5e9f2a55ecaf6 214 Gene3D G3DSA:1.10.357.10 13 185 1.3E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SMD11_RS03455 2dabf396b37795fd7cd5e9f2a55ecaf6 214 SUPERFAMILY SSF46689 12 92 4.31E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 SMD11_RS03455 2dabf396b37795fd7cd5e9f2a55ecaf6 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 3.8E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS03455 2dabf396b37795fd7cd5e9f2a55ecaf6 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 3.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS03455 2dabf396b37795fd7cd5e9f2a55ecaf6 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 3.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SMD11_RS11085 13d5548dc88e3b1f704e289f5533893e 443 Gene3D G3DSA:2.130.10.10 51 364 9.2E-26 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SMD11_RS11085 13d5548dc88e3b1f704e289f5533893e 443 SUPERFAMILY SSF82171 52 425 2.16E-24 T 06-07-2017 SMD11_RS11085 13d5548dc88e3b1f704e289f5533893e 443 Pfam PF07676 WD40-like Beta Propeller Repeat 105 136 0.046 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS11085 13d5548dc88e3b1f704e289f5533893e 443 Pfam PF07676 WD40-like Beta Propeller Repeat 343 372 0.0045 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS11085 13d5548dc88e3b1f704e289f5533893e 443 Pfam PF07676 WD40-like Beta Propeller Repeat 160 192 1.3E-4 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS11085 13d5548dc88e3b1f704e289f5533893e 443 Pfam PF07676 WD40-like Beta Propeller Repeat 49 83 0.034 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS11085 13d5548dc88e3b1f704e289f5533893e 443 Pfam PF07676 WD40-like Beta Propeller Repeat 289 304 0.3 T 06-07-2017 IPR011659 WD40-like Beta Propeller SMD11_RS16070 90f1c22962f47948ab4508e44163e1c4 97 SUPERFAMILY SSF54909 2 92 4.18E-16 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel SMD11_RS16070 90f1c22962f47948ab4508e44163e1c4 97 Pfam PF07876 Stress responsive A/B Barrel Domain 2 96 4.0E-20 T 06-07-2017 IPR013097 Stress responsive alpha-beta barrel SMD11_RS16070 90f1c22962f47948ab4508e44163e1c4 97 Gene3D G3DSA:3.30.70.900 1 95 1.7E-22 T 06-07-2017 SMD11_RS16070 90f1c22962f47948ab4508e44163e1c4 97 SMART SM00886 2 97 9.5E-22 T 06-07-2017 IPR013097 Stress responsive alpha-beta barrel SMD11_RS09815 7fba3263b679ab056e5bd3586f6511bb 167 Pfam PF13826 Domain of unknown function (DUF4188) 19 139 8.6E-39 T 06-07-2017 IPR025444 Protein of unknown function DUF4188 SMD11_RS00765 b3f6fd680b7cbff32f277163bfeb9968 461 Gene3D G3DSA:1.10.260.40 6 72 1.5E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS00765 b3f6fd680b7cbff32f277163bfeb9968 461 Gene3D G3DSA:1.25.40.10 262 416 5.3E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SMD11_RS24445 aadb8d5113cdd14070bc1ae1e8970f58 254 Pfam PF13649 Methyltransferase domain 41 137 2.0E-14 T 06-07-2017 SMD11_RS24445 aadb8d5113cdd14070bc1ae1e8970f58 254 SUPERFAMILY SSF53335 16 207 3.5E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS24445 aadb8d5113cdd14070bc1ae1e8970f58 254 Gene3D G3DSA:3.40.50.150 29 211 1.7E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS27780 4617f5d8d75e5d81181cc76c6ae2d9f5 339 PIRSF PIRSF037196 28 339 2.6E-96 T 06-07-2017 IPR017133 Pyoverdine chromophore biosynthesis protein PvcA SMD11_RS27780 4617f5d8d75e5d81181cc76c6ae2d9f5 339 Pfam PF05141 Pyoverdine/dityrosine biosynthesis protein 75 322 2.5E-72 T 06-07-2017 IPR007817 Pyoverdine biosynthesis SMD11_RS31010 d5ce64474050c57d0bb679759f5c0e53 366 Pfam PF01699 Sodium/calcium exchanger protein 222 363 2.6E-12 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 SMD11_RS31010 d5ce64474050c57d0bb679759f5c0e53 366 Pfam PF01699 Sodium/calcium exchanger protein 37 188 1.3E-12 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 SMD11_RS28850 1481496337482c09fc8e903b67396033 283 Pfam PF10021 Uncharacterized protein conserved in bacteria (DUF2263) 9 152 3.6E-47 T 06-07-2017 IPR019261 Domain of unknown function DUF2263 SMD11_RS28850 1481496337482c09fc8e903b67396033 283 TIGRFAM TIGR02452 TIGR02452: TIGR02452 family protein 8 266 2.1E-90 T 06-07-2017 IPR012664 Conserved hypothetical protein CHP02452 SMD11_RS28850 1481496337482c09fc8e903b67396033 283 PIRSF PIRSF014899 1 273 3.8E-109 T 06-07-2017 IPR012664 Conserved hypothetical protein CHP02452 SMD11_RS00580 8d545d654bd7296d5dbcbe1b0a8c2916 324 Gene3D G3DSA:1.10.620.20 68 247 1.8E-9 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 SMD11_RS00580 8d545d654bd7296d5dbcbe1b0a8c2916 324 SUPERFAMILY SSF47240 52 250 7.1E-21 T 06-07-2017 IPR009078 Ferritin-like superfamily SMD11_RS29630 e3ce263f2d08a3144919e0a1006c47e1 236 Gene3D G3DSA:2.40.440.10 124 230 3.4E-12 T 06-07-2017 SMD11_RS29630 e3ce263f2d08a3144919e0a1006c47e1 236 Pfam PF03734 L,D-transpeptidase catalytic domain 120 229 8.3E-15 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 SMD11_RS29630 e3ce263f2d08a3144919e0a1006c47e1 236 SUPERFAMILY SSF141523 119 230 1.19E-20 T 06-07-2017 SMD11_RS04585 51163f6dce100d9a7b0ca84547db8cd4 305 Pfam PF12679 ABC-2 family transporter protein 66 293 3.4E-10 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 SMD11_RS21515 9f151eda6e43a539905cfc708cbb27ac 250 Pfam PF04203 Sortase family 98 244 1.5E-11 T 06-07-2017 IPR005754 Sortase family SMD11_RS14465 d741c99e520a2677d8b2d7af9012d2c3 326 Pfam PF06089 L-asparaginase II 21 314 1.5E-110 T 06-07-2017 IPR010349 L-asparaginase II SMD11_RS26495 d0c7d634c01d1963b84c19974a3c8095 98 SUPERFAMILY SSF54862 13 90 1.95E-9 T 06-07-2017 SMD11_RS26495 d0c7d634c01d1963b84c19974a3c8095 98 Gene3D G3DSA:3.30.70.20 11 95 6.0E-28 T 06-07-2017 SMD11_RS26495 d0c7d634c01d1963b84c19974a3c8095 98 Pfam PF13459 4Fe-4S single cluster domain 13 83 7.0E-19 T 06-07-2017 SMD11_RS26495 d0c7d634c01d1963b84c19974a3c8095 98 PRINTS PR00352 3Fe-4S ferredoxin signature 15 26 1.0E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD11_RS26495 d0c7d634c01d1963b84c19974a3c8095 98 PRINTS PR00352 3Fe-4S ferredoxin signature 26 36 1.0E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD11_RS26495 d0c7d634c01d1963b84c19974a3c8095 98 PRINTS PR00352 3Fe-4S ferredoxin signature 69 81 1.0E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 SMD11_RS30350 3c0c7d44bf51619daed643e665c9f41a 146 Gene3D G3DSA:3.10.180.10 13 143 3.0E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS30350 3c0c7d44bf51619daed643e665c9f41a 146 SUPERFAMILY SSF54593 5 143 1.51E-19 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SMD11_RS30350 3c0c7d44bf51619daed643e665c9f41a 146 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 141 1.2E-7 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SMD11_RS21965 6dc407d693d73ac07d9972ac8796e54b 79 Pfam PF03777 Small secreted domain (DUF320) 23 78 3.3E-26 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD11_RS18400 056c3f5cbe898785e6c49ee30d3b7f91 174 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 28 146 5.4E-10 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 SMD11_RS18400 056c3f5cbe898785e6c49ee30d3b7f91 174 SUPERFAMILY SSF55961 13 169 3.39E-25 T 06-07-2017 SMD11_RS18400 056c3f5cbe898785e6c49ee30d3b7f91 174 Gene3D G3DSA:3.30.530.20 14 170 2.3E-24 T 06-07-2017 IPR023393 START-like domain SMD11_RS00665 f49645a784dba316c60dcb723639251a 397 Gene3D G3DSA:3.40.50.10540 312 390 1.2E-92 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS00665 f49645a784dba316c60dcb723639251a 397 Gene3D G3DSA:3.40.50.10540 12 224 1.2E-92 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS00665 f49645a784dba316c60dcb723639251a 397 Gene3D G3DSA:3.30.1540.10 232 311 2.4E-25 T 06-07-2017 SMD11_RS00665 f49645a784dba316c60dcb723639251a 397 Pfam PF02515 CoA-transferase family III 14 379 8.4E-102 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 SMD11_RS00665 f49645a784dba316c60dcb723639251a 397 SUPERFAMILY SSF89796 11 390 5.23E-111 T 06-07-2017 IPR023606 CoA-transferase family III domain SMD11_RS20040 df117b2d8e75e95539f52bc887d31617 586 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 80 235 2.9E-19 T 06-07-2017 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 SMD11_RS20040 df117b2d8e75e95539f52bc887d31617 586 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 392 585 4.4E-25 T 06-07-2017 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 SMD11_RS20885 6588ca284e318d1ad825399380b10a9e 592 SUPERFAMILY SSF53448 22 250 1.41E-40 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20885 6588ca284e318d1ad825399380b10a9e 592 Gene3D G3DSA:3.90.550.10 23 256 5.0E-35 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases SMD11_RS20885 6588ca284e318d1ad825399380b10a9e 592 Pfam PF00535 Glycosyl transferase family 2 24 151 6.6E-23 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SMD11_RS14135 ae7bc817921a862ef816e7eee925fa58 415 Pfam PF01757 Acyltransferase family 26 339 6.6E-28 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 SMD11_RS30760 86d5b3b8061c85e1030efacee88340d5 328 SUPERFAMILY SSF51430 8 311 1.7E-100 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS30760 86d5b3b8061c85e1030efacee88340d5 328 Pfam PF00248 Aldo/keto reductase family 18 307 5.2E-76 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS30760 86d5b3b8061c85e1030efacee88340d5 328 Gene3D G3DSA:3.20.20.100 4 318 4.0E-115 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS28370 b23f86c0a8adb0904d906d1df8fcfa2a 474 Gene3D G3DSA:3.50.50.60 13 198 8.2E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS28370 b23f86c0a8adb0904d906d1df8fcfa2a 474 Gene3D G3DSA:3.50.50.60 317 367 8.2E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS28370 b23f86c0a8adb0904d906d1df8fcfa2a 474 SUPERFAMILY SSF51905 308 374 6.49E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS28370 b23f86c0a8adb0904d906d1df8fcfa2a 474 SUPERFAMILY SSF51905 13 204 6.49E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS33475 17497428329b2da18892a81bdd917119 208 Gene3D G3DSA:2.160.10.10 87 191 3.4E-13 T 06-07-2017 SMD11_RS33475 17497428329b2da18892a81bdd917119 208 SUPERFAMILY SSF51161 3 191 2.36E-21 T 06-07-2017 IPR011004 Trimeric LpxA-like SMD11_RS33475 17497428329b2da18892a81bdd917119 208 Gene3D G3DSA:3.50.50.60 3 44 2.3E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS32600 f939d4e7ea37980437f90d2e8d685cc7 231 Pfam PF02361 Cobalt transport protein 13 202 2.0E-13 T 06-07-2017 IPR003339 ABC/ECF transporter, transmembrane component SMD11_RS03645 45bd4e8b5737f18f9785999bb0347a03 339 Gene3D G3DSA:2.120.10.30 88 321 6.1E-13 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like SMD11_RS03645 45bd4e8b5737f18f9785999bb0347a03 339 SUPERFAMILY SSF82171 44 324 5.3E-14 T 06-07-2017 SMD11_RS15295 d1f7a2eb4e1eca3e6b258ca65ed71df1 148 Pfam PF13581 Histidine kinase-like ATPase domain 8 139 1.9E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS03445 7ea912a6be29b7e2f9fa7c61d8b09d93 276 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 71 231 2.9E-10 T 06-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 SMD11_RS03445 7ea912a6be29b7e2f9fa7c61d8b09d93 276 Gene3D G3DSA:3.40.640.10 95 232 2.9E-30 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SMD11_RS03445 7ea912a6be29b7e2f9fa7c61d8b09d93 276 SUPERFAMILY SSF53383 35 231 2.83E-37 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase SMD11_RS08795 8f51ab81b3e0b93f67ae05d07b33a754 153 SUPERFAMILY SSF54427 2 134 2.85E-63 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS08795 8f51ab81b3e0b93f67ae05d07b33a754 153 Pfam PF07080 Protein of unknown function (DUF1348) 4 132 7.7E-63 T 06-07-2017 IPR009783 Protein of unknown function DUF1348 SMD11_RS08795 8f51ab81b3e0b93f67ae05d07b33a754 153 Gene3D G3DSA:3.10.450.50 12 135 1.4E-59 T 06-07-2017 IPR032710 NTF2-like domain SMD11_RS05745 002c58164292f71a5c204a12e876068b 443 Pfam PF10011 Predicted membrane protein (DUF2254) 28 396 2.3E-102 T 06-07-2017 IPR018723 Protein of unknown function DUF2254, membrane SMD11_RS12770 fb456713fe8183ece5244eac7271e66d 69 Pfam PF04149 Domain of unknown function (DUF397) 5 57 1.1E-13 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS33635 74836cdbf936abf69c4bbdf7c8f91027 163 SMART SM00347 45 142 2.4E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS33635 74836cdbf936abf69c4bbdf7c8f91027 163 Gene3D G3DSA:1.10.10.10 18 155 2.7E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33635 74836cdbf936abf69c4bbdf7c8f91027 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 98 7.4E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS33635 74836cdbf936abf69c4bbdf7c8f91027 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 132 152 7.4E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS33635 74836cdbf936abf69c4bbdf7c8f91027 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 82 7.4E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS33635 74836cdbf936abf69c4bbdf7c8f91027 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 102 118 7.4E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS33635 74836cdbf936abf69c4bbdf7c8f91027 163 SUPERFAMILY SSF46785 15 156 3.17E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS33635 74836cdbf936abf69c4bbdf7c8f91027 163 Pfam PF01047 MarR family 53 105 2.9E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SMD11_RS13120 d657b8264bb9f1485b34bf34f983589a 394 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 393 2.2E-134 T 06-07-2017 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain SMD11_RS13120 d657b8264bb9f1485b34bf34f983589a 394 SUPERFAMILY SSF56059 1 169 5.65E-72 T 06-07-2017 SMD11_RS13120 d657b8264bb9f1485b34bf34f983589a 394 SUPERFAMILY SSF56059 279 392 5.65E-72 T 06-07-2017 SMD11_RS13120 d657b8264bb9f1485b34bf34f983589a 394 SUPERFAMILY SSF52440 177 292 3.16E-34 T 06-07-2017 IPR016185 Pre-ATP-grasp domain SMD11_RS12325 875c4085aa9825336c61ea9eb3f89d1c 312 Pfam PF00482 Type II secretion system (T2SS), protein F 145 268 2.8E-18 T 06-07-2017 IPR018076 Type II secretion system F domain SMD11_RS08930 0fed242c8b7aa6a91d21a0dc0f341196 584 Pfam PF01494 FAD binding domain 3 350 5.9E-43 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 SMD11_RS08930 0fed242c8b7aa6a91d21a0dc0f341196 584 Gene3D G3DSA:3.50.50.60 280 359 8.1E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS08930 0fed242c8b7aa6a91d21a0dc0f341196 584 Gene3D G3DSA:3.50.50.60 115 194 8.1E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS08930 0fed242c8b7aa6a91d21a0dc0f341196 584 Gene3D G3DSA:3.50.50.60 4 74 8.1E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS08930 0fed242c8b7aa6a91d21a0dc0f341196 584 SUPERFAMILY SSF51905 3 189 4.33E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS08930 0fed242c8b7aa6a91d21a0dc0f341196 584 SUPERFAMILY SSF51905 279 376 4.33E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SMD11_RS08930 0fed242c8b7aa6a91d21a0dc0f341196 584 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 323 2.1E-27 T 06-07-2017 SMD11_RS08930 0fed242c8b7aa6a91d21a0dc0f341196 584 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 325 343 2.1E-27 T 06-07-2017 SMD11_RS08930 0fed242c8b7aa6a91d21a0dc0f341196 584 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 168 183 2.1E-27 T 06-07-2017 SMD11_RS08930 0fed242c8b7aa6a91d21a0dc0f341196 584 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 2.1E-27 T 06-07-2017 SMD11_RS08930 0fed242c8b7aa6a91d21a0dc0f341196 584 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.1E-27 T 06-07-2017 SMD11_RS07135 d8a757d75d175b276a0b003afbf62348 354 Pfam PF10935 Protein of unknown function (DUF2637) 70 223 2.1E-23 T 06-07-2017 IPR021235 Protein of unknown function DUF2637 SMD11_RS07445 4b88e2edfbb4747a6ce3912a08ab8de1 276 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 9 257 4.1E-32 T 06-07-2017 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain SMD11_RS14580 788c2c78fdc7384dd74c4abf5cfbd367 133 Pfam PF02583 Metal-sensitive transcriptional repressor 48 128 3.8E-30 T 06-07-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 SMD11_RS28020 bbb3c6c58ca784dd66ce8483fe433263 322 Pfam PF06166 Protein of unknown function (DUF979) 5 322 5.4E-116 T 06-07-2017 IPR009323 Protein of unknown function DUF979 SMD11_RS02740 04897eac62562f11e2a1d8d6b3b80476 351 Pfam PF12051 Protein of unknown function (DUF3533) 150 328 5.7E-7 T 06-07-2017 IPR022703 Domain of unknown function DUF3533 SMD11_RS12795 3975068ea4ae30fb6021f0b8a0fed0cb 443 Gene3D G3DSA:1.10.260.40 12 75 1.4E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS12795 3975068ea4ae30fb6021f0b8a0fed0cb 443 SUPERFAMILY SSF47413 8 76 2.61E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS03755 36ba193e955266ad917dc659e5696395 689 Pfam PF03644 Glycosyl hydrolase family 85 120 416 5.6E-78 T 06-07-2017 IPR005201 Glycoside hydrolase, family 85 GO:0005737|GO:0033925 KEGG: 00511+3.2.1.96 SMD11_RS06235 04e87bb3c053914077e1bbceb0d8dba7 204 Pfam PF09335 SNARE associated Golgi protein 40 169 8.5E-12 T 06-07-2017 IPR032816 SNARE associated Golgi protein SMD11_RS15620 6cf4e53203f8c51f42ae06297cf25fe8 218 Pfam PF16702 Domain of unknown function (DUF5063) 13 173 5.1E-44 T 06-07-2017 IPR032025 Protein of unknown function DUF5063 SMD11_RS17915 1ae412c133cb4982f9a5ad849ab8d3a1 84 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 79 5.7E-29 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD11_RS17915 1ae412c133cb4982f9a5ad849ab8d3a1 84 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 79 3.8E-21 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD11_RS17915 1ae412c133cb4982f9a5ad849ab8d3a1 84 Gene3D G3DSA:3.30.1280.10 3 80 5.0E-33 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD11_RS17915 1ae412c133cb4982f9a5ad849ab8d3a1 84 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 2.0E-31 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD11_RS17915 1ae412c133cb4982f9a5ad849ab8d3a1 84 SUPERFAMILY SSF82697 3 78 2.62E-25 T 06-07-2017 SMD11_RS17915 1ae412c133cb4982f9a5ad849ab8d3a1 84 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 21.78 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 SMD11_RS22675 cc709a8da1869a9a1edd967a584588ac 65 Pfam PF04149 Domain of unknown function (DUF397) 5 56 6.3E-9 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS28375 4335fd09aa4c30350a8dee9e01b44cc0 475 Pfam PF06762 Lipase maturation factor 121 270 2.7E-60 T 06-07-2017 IPR009613 Lipase maturation factor Reactome: R-HSA-192456 SMD11_RS28375 4335fd09aa4c30350a8dee9e01b44cc0 475 Pfam PF06762 Lipase maturation factor 296 472 6.7E-64 T 06-07-2017 IPR009613 Lipase maturation factor Reactome: R-HSA-192456 SMD11_RS10505 628068df959c283d2912963c51ed86bd 280 Gene3D G3DSA:1.10.3720.10 7 264 1.4E-51 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS10505 628068df959c283d2912963c51ed86bd 280 SUPERFAMILY SSF161098 9 276 1.27E-57 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS10505 628068df959c283d2912963c51ed86bd 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 268 2.0E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS00080 8046fa908609c7e9e46fa654f17d98d7 599 Gene3D G3DSA:3.90.1720.10 456 599 4.1E-12 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain SMD11_RS00080 8046fa908609c7e9e46fa654f17d98d7 599 SUPERFAMILY SSF54001 456 578 1.47E-7 T 06-07-2017 SMD11_RS13465 c9a1a6656adf56c17fc98583e34d52f7 276 Pfam PF14219 Domain of unknown function (DUF4328) 81 238 8.0E-42 T 06-07-2017 IPR025565 Domain of unknown function DUF4328 SMD11_RS25005 b5654b29af243019e42bae92a1503f6a 244 SUPERFAMILY SSF140453 65 144 3.4E-5 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like SMD11_RS12240 e77ed74bf919ff6466b633b3579f89da 477 Pfam PF01594 Domain of unknown function DUF20 104 428 1.9E-60 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like SMD11_RS02180 84301a3e9e440f5272a12a7a279c1848 171 SUPERFAMILY SSF69255 7 84 4.84E-16 T 06-07-2017 SMD11_RS02180 84301a3e9e440f5272a12a7a279c1848 171 Gene3D G3DSA:2.40.50.230 14 84 2.9E-10 T 06-07-2017 IPR006531 Gp5 N-terminal SMD11_RS17555 dbb254c6260b7807f33b8916bd497643 242 Pfam PF14016 Protein of unknown function (DUF4232) 112 233 1.1E-22 T 06-07-2017 IPR025326 Protein of unknown function DUF4232 SMD11_RS07230 0f0d1f5a535d63a0dca445204a2f7693 301 Gene3D G3DSA:1.10.3720.10 90 288 2.4E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS07230 0f0d1f5a535d63a0dca445204a2f7693 301 SUPERFAMILY SSF161098 91 279 1.57E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS07230 0f0d1f5a535d63a0dca445204a2f7693 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 281 1.0E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SMD11_RS06860 a0105cba06812f036e17335c438561a3 228 Pfam PF01810 LysE type translocator 35 219 6.6E-14 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 SMD11_RS33390 8b341eb3a75fcef5aabbd2209a30928c 436 Pfam PF02666 Phosphatidylserine decarboxylase 212 407 1.2E-38 T 06-07-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 SMD11_RS33390 8b341eb3a75fcef5aabbd2209a30928c 436 Pfam PF12588 Phophatidylserine decarboxylase 61 191 8.0E-30 T 06-07-2017 IPR022237 Phophatidylserine decarboxylase SMD11_RS30185 f976ad47e15c1ef978b142a539d926b6 401 Gene3D G3DSA:1.10.10.10 308 383 2.0E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS30185 f976ad47e15c1ef978b142a539d926b6 401 Pfam PF13556 PucR C-terminal helix-turn-helix domain 308 361 3.8E-16 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain SMD11_RS25845 06741411ca8a3c6583e99a0eba21cc71 242 Pfam PF10127 Predicted nucleotidyltransferase 19 225 4.5E-40 T 06-07-2017 IPR018775 Nucleotidyltransferase, predicted SMD11_RS04735 d7ae917dfc4e84a4f39ac265a40846fe 392 Pfam PF13556 PucR C-terminal helix-turn-helix domain 323 379 5.4E-15 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain SMD11_RS08105 90d52fc2ef7df18db54f0812458b5a9a 389 Pfam PF01757 Acyltransferase family 9 348 1.5E-27 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 SMD11_RS09085 0069def25f39cb9f21b4735c91396a29 186 Pfam PF10756 Bacterial PH domain 96 152 1.0E-4 T 06-07-2017 IPR019692 Protein of unknown function DUF2581 SMD11_RS27990 4b0c8d755b4c7e73141ad3ce2c430637 143 Pfam PF03779 SPW repeat 89 136 9.6E-13 T 06-07-2017 IPR005530 SPW repeat SMD11_RS27990 4b0c8d755b4c7e73141ad3ce2c430637 143 Pfam PF03779 SPW repeat 38 74 1.7E-10 T 06-07-2017 IPR005530 SPW repeat SMD11_RS00340 6b48e9a13151f19e35abcea82b4a92c0 358 SUPERFAMILY SSF48576 20 346 1.93E-47 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS00340 6b48e9a13151f19e35abcea82b4a92c0 358 Gene3D G3DSA:1.10.600.10 21 334 1.2E-67 T 06-07-2017 IPR008949 Isoprenoid synthase domain SMD11_RS16365 3228a2459f41fc1f6b2499dac3034508 402 Pfam PF01757 Acyltransferase family 19 366 4.6E-30 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 SMD11_RS30390 18902eac1f721dab61b991b252cc9870 218 Pfam PF00652 Ricin-type beta-trefoil lectin domain 82 212 3.3E-10 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS30390 18902eac1f721dab61b991b252cc9870 218 Gene3D G3DSA:2.80.10.50 80 213 9.9E-12 T 06-07-2017 SMD11_RS30390 18902eac1f721dab61b991b252cc9870 218 SUPERFAMILY SSF50370 80 214 1.66E-16 T 06-07-2017 IPR000772 Ricin B, lectin domain SMD11_RS10825 ed3cca1778ce4fb8656016720a4d3c75 465 Pfam PF00953 Glycosyl transferase family 4 87 246 1.5E-34 T 06-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 SMD11_RS02240 3903a462d22c4bb4ecb05ead2c70f0d6 617 Pfam PF04984 Phage tail sheath protein 5 609 4.1E-56 T 06-07-2017 IPR007067 Tail sheath protein SMD11_RS28160 ccc2c0fad35bb3b2807cbf7147015bbb 110 PIRSF PIRSF018579 1 110 1.2E-46 T 06-07-2017 IPR009709 Protein of unknown function DUF1290 SMD11_RS28160 ccc2c0fad35bb3b2807cbf7147015bbb 110 Pfam PF06947 Protein of unknown function (DUF1290) 21 108 5.1E-35 T 06-07-2017 IPR009709 Protein of unknown function DUF1290 SMD11_RS23335 8e4ae6e29095e2a86369cfa78e91e4ca 259 Pfam PF13349 Putative adhesin 141 257 5.0E-14 T 06-07-2017 IPR025164 Putative adhesin SMD11_RS25635 d94aac58e5b9809d1cbfc723c27e00c7 88 Pfam PF03777 Small secreted domain (DUF320) 32 87 2.9E-26 T 06-07-2017 IPR005528 Domain of unknown function DUF320, Streptomyces species SMD11_RS24200 a32f604d7741d84ed72e9d0e989ef0cb 132 Pfam PF12270 Cytochrome c oxidase subunit IV 2 130 3.9E-52 T 06-07-2017 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 SMD11_RS24200 a32f604d7741d84ed72e9d0e989ef0cb 132 PIRSF PIRSF017385 1 131 9.8E-49 T 06-07-2017 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 SMD11_RS29450 06fc088fe295c236dd436810f584ccc3 454 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 140 310 2.2E-27 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS29450 06fc088fe295c236dd436810f584ccc3 454 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 140 310 4.5E-40 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain SMD11_RS11765 582dc21eab628f9734710b73534f0709 194 Pfam PF05076 Suppressor of fused protein (SUFU) 29 188 1.2E-32 T 06-07-2017 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 SMD11_RS31505 456a5c4ba459791e8c2fd8515dce8f60 127 SUPERFAMILY SSF103196 3 103 6.54E-5 T 06-07-2017 SMD11_RS04440 66431927289e95b223ce05c913e7b504 218 Pfam PF14273 Domain of unknown function (DUF4360) 34 213 2.2E-70 T 06-07-2017 IPR025649 Protein of unknown function DUF4360 SMD11_RS27075 19fc66620938e0aec9d1e8c0b5dc0697 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 3.5E-38 T 06-07-2017 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 SMD11_RS24930 12643a8bb0543837792b07fd4c601d8f 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 293 7.8E-48 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD11_RS06715 a7958e7e440ba1be34d30f8dd26ed3cc 338 Gene3D G3DSA:3.20.20.100 1 315 3.7E-99 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS06715 a7958e7e440ba1be34d30f8dd26ed3cc 338 Pfam PF00248 Aldo/keto reductase family 16 314 2.2E-75 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS06715 a7958e7e440ba1be34d30f8dd26ed3cc 338 SUPERFAMILY SSF51430 1 316 3.67E-98 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain SMD11_RS26065 37102e701e2f7ac3990d1835bf395dda 411 Pfam PF13520 Amino acid permease 2 404 1.5E-37 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS26065 37102e701e2f7ac3990d1835bf395dda 411 PIRSF PIRSF006060 1 406 1.3E-50 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS06450 17bf7f14a1884a07f5fc691117bd0063 526 Gene3D G3DSA:1.20.1250.20 490 520 2.5E-21 T 06-07-2017 SMD11_RS06450 17bf7f14a1884a07f5fc691117bd0063 526 Gene3D G3DSA:1.20.1250.20 281 438 2.5E-21 T 06-07-2017 SMD11_RS06450 17bf7f14a1884a07f5fc691117bd0063 526 Pfam PF07690 Major Facilitator Superfamily 35 427 2.2E-54 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS06450 17bf7f14a1884a07f5fc691117bd0063 526 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 31 437 1.6E-81 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SMD11_RS06450 17bf7f14a1884a07f5fc691117bd0063 526 SUPERFAMILY SSF103473 489 517 1.7E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS06450 17bf7f14a1884a07f5fc691117bd0063 526 SUPERFAMILY SSF103473 266 437 1.7E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS06450 17bf7f14a1884a07f5fc691117bd0063 526 SUPERFAMILY SSF103473 26 213 1.7E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS06450 17bf7f14a1884a07f5fc691117bd0063 526 Gene3D G3DSA:1.20.1250.20 31 214 3.4E-31 T 06-07-2017 SMD11_RS31215 ff431e3f5edda6e3b40c6cf6a6f27ff3 97 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 44 92 1.8E-15 T 06-07-2017 IPR027805 Transposase, Helix-turn-helix domain SMD11_RS31215 ff431e3f5edda6e3b40c6cf6a6f27ff3 97 Gene3D G3DSA:1.10.10.10 17 86 3.1E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02065 f513edfd65a83e87e99e9932a1e748a8 215 Pfam PF14273 Domain of unknown function (DUF4360) 46 212 3.2E-39 T 06-07-2017 IPR025649 Protein of unknown function DUF4360 SMD11_RS11690 d85edb3112378af1903b8bc367f8a159 499 SUPERFAMILY SSF55486 360 489 3.29E-14 T 06-07-2017 SMD11_RS11690 d85edb3112378af1903b8bc367f8a159 499 Pfam PF11350 Protein of unknown function (DUF3152) 318 497 1.5E-58 T 06-07-2017 IPR022603 Domain of unknown function DUF3152 SMD11_RS25615 24d2dfd2c585d1d7e708cf2c6a473f15 233 Gene3D G3DSA:3.40.109.10 36 231 1.4E-45 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS25615 24d2dfd2c585d1d7e708cf2c6a473f15 233 SUPERFAMILY SSF55469 34 232 3.01E-41 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SMD11_RS25615 24d2dfd2c585d1d7e708cf2c6a473f15 233 Pfam PF00881 Nitroreductase family 43 211 3.2E-22 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 SMD11_RS14130 fde5003388ee4d1cfa5fe7d515e505da 333 Pfam PF01757 Acyltransferase family 1 307 1.2E-19 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 SMD11_RS29740 01dd046dd7b35336fa73c6162b5d8466 337 Pfam PF03756 A-factor biosynthesis hotdog domain 51 183 1.9E-16 T 06-07-2017 IPR005509 A-factor biosynthesis hotdog domain SMD11_RS29740 01dd046dd7b35336fa73c6162b5d8466 337 Pfam PF03756 A-factor biosynthesis hotdog domain 240 321 2.9E-9 T 06-07-2017 IPR005509 A-factor biosynthesis hotdog domain SMD11_RS13720 c1c10cd6d76237d25069c2a29a7c54f7 168 Pfam PF13471 Transglutaminase-like superfamily 21 132 1.4E-27 T 06-07-2017 IPR032708 Microcin J25-processing protein McjB, C-terminal SMD11_RS31455 92d6a1949113cf339308d81af59ca246 642 SUPERFAMILY SSF53067 2 150 5.96E-7 T 06-07-2017 SMD11_RS31455 92d6a1949113cf339308d81af59ca246 642 Gene3D G3DSA:3.30.420.40 2 181 3.0E-9 T 06-07-2017 SMD11_RS31455 92d6a1949113cf339308d81af59ca246 642 SUPERFAMILY SSF53067 166 366 7.5E-15 T 06-07-2017 SMD11_RS30080 974dfb806cfc96300f1b241ba90487bf 122 Gene3D G3DSA:1.10.101.10 56 120 3.0E-16 T 06-07-2017 IPR002477 Peptidoglycan binding-like SMD11_RS30080 974dfb806cfc96300f1b241ba90487bf 122 Pfam PF01471 Putative peptidoglycan binding domain 64 120 2.3E-13 T 06-07-2017 IPR002477 Peptidoglycan binding-like SMD11_RS30080 974dfb806cfc96300f1b241ba90487bf 122 SUPERFAMILY SSF47090 54 120 9.26E-15 T 06-07-2017 IPR002477 Peptidoglycan binding-like SMD11_RS23705 5b17160f86e37505f221781dfd49e260 244 SMART SM00943 36 216 1.1E-29 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD11_RS23705 5b17160f86e37505f221781dfd49e260 244 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 37 211 1.1E-26 T 06-07-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SMD11_RS05890 9ec0cc4ddee8f7fc699b628f38674a4c 194 Pfam PF11774 Lsr2 89 163 1.7E-5 T 06-07-2017 IPR024412 Lsr2 SMD11_RS21300 c38b47dafe78475904cac0bb6c5c472f 155 SUPERFAMILY SSF52833 4 153 1.64E-45 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS21300 c38b47dafe78475904cac0bb6c5c472f 155 Gene3D G3DSA:3.40.30.10 2 153 3.6E-47 T 06-07-2017 IPR012336 Thioredoxin-like fold SMD11_RS21300 c38b47dafe78475904cac0bb6c5c472f 155 Pfam PF00578 AhpC/TSA family 8 134 2.4E-35 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SMD11_RS32990 87f49fbc4fe1984745e3269167a6c465 235 SUPERFAMILY SSF52540 4 182 1.06E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS22125 9975744bcfbabbc10a0c7fa2cd0ed963 172 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 163 1.6E-59 T 06-07-2017 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger SMD11_RS32880 7c98f4e949d784aa52c7fcae7ecba072 71 SMART SM00923 3 53 2.0E-20 T 06-07-2017 IPR005153 MbtH-like protein SMD11_RS32880 7c98f4e949d784aa52c7fcae7ecba072 71 SUPERFAMILY SSF160582 1 68 1.57E-25 T 06-07-2017 SMD11_RS32880 7c98f4e949d784aa52c7fcae7ecba072 71 Pfam PF03621 MbtH-like protein 1 52 6.4E-21 T 06-07-2017 IPR005153 MbtH-like protein SMD11_RS32880 7c98f4e949d784aa52c7fcae7ecba072 71 Gene3D G3DSA:3.90.820.10 12 68 1.3E-26 T 06-07-2017 SMD11_RS01255 b4fb62ff278df51497e37c00043800b7 476 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 55 204 6.8E-7 T 06-07-2017 SMD11_RS19805 62c3265a1beff17d6505f6099e95a624 395 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 13 366 3.4E-94 T 06-07-2017 IPR010640 Low temperature requirement A SMD11_RS13765 575cee723de2bad5b851021e4c44cbae 489 Pfam PF00860 Permease family 41 441 3.2E-31 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD11_RS24450 afca127c701cf93336cecf3aa190a000 134 Pfam PF11239 Protein of unknown function (DUF3040) 1 81 2.0E-27 T 06-07-2017 IPR021401 Protein of unknown function DUF3040 SMD11_RS21210 0cd89d9299b549d9cdc14c96b73100a7 196 Pfam PF09438 Domain of unknown function (DUF2017) 9 194 4.8E-61 T 06-07-2017 IPR018561 Domain of unknown function DUF2017 SMD11_RS08165 2da8c005f44ea8249c4ef6dcf4b4c032 354 Gene3D G3DSA:3.40.50.720 36 336 2.3E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS08165 2da8c005f44ea8249c4ef6dcf4b4c032 354 Pfam PF01370 NAD dependent epimerase/dehydratase family 36 263 3.6E-36 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 SMD11_RS08165 2da8c005f44ea8249c4ef6dcf4b4c032 354 SUPERFAMILY SSF51735 32 340 1.1E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS25085 1538ccf7ab8a9e6e9a2b659d0c333717 216 Pfam PF12385 Papain-like cysteine protease AvrRpt2 54 185 1.1E-15 T 06-07-2017 IPR022118 Peptidase C70, AvrRpt2 SMD11_RS23000 94d1942ee994566b5431e5e59a42e034 287 Gene3D G3DSA:3.20.20.60 3 249 1.7E-59 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS23000 94d1942ee994566b5431e5e59a42e034 287 Pfam PF13714 Phosphoenolpyruvate phosphomutase 16 245 1.4E-36 T 06-07-2017 SMD11_RS23000 94d1942ee994566b5431e5e59a42e034 287 SUPERFAMILY SSF51621 4 250 1.03E-61 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SMD11_RS02905 564cce6cd7ed7696f79b4dbfd585bcb2 265 SUPERFAMILY SSF53681 106 224 1.96E-16 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS02905 564cce6cd7ed7696f79b4dbfd585bcb2 265 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 67 75 - T 06-07-2017 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS02905 564cce6cd7ed7696f79b4dbfd585bcb2 265 Gene3D G3DSA:3.40.50.1860 2 155 1.2E-35 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS02905 564cce6cd7ed7696f79b4dbfd585bcb2 265 SUPERFAMILY SSF53681 2 103 2.42E-21 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS02905 564cce6cd7ed7696f79b4dbfd585bcb2 265 Pfam PF01177 Asp/Glu/Hydantoin racemase 28 191 9.7E-11 T 06-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SMD11_RS07505 b818d204d267d2e405a514e4977363e4 362 SUPERFAMILY SSF89372 9 319 4.84E-16 T 06-07-2017 SMD11_RS22870 c1a3118ef63d6dfc21d89de517b40b34 136 SUPERFAMILY SSF46785 11 130 1.7E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS22870 c1a3118ef63d6dfc21d89de517b40b34 136 Pfam PF01475 Ferric uptake regulator family 11 125 1.9E-32 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 SMD11_RS22870 c1a3118ef63d6dfc21d89de517b40b34 136 Gene3D G3DSA:1.10.10.10 11 78 2.3E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS02160 1d8bdf16762e585149a9c789d4cdd0b1 1302 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 607 1189 1.7E-59 T 06-07-2017 IPR011749 Conserved hypothetical protein CHP02243 SMD11_RS28195 cae73f991628f9b17351a4fce37e5196 128 Pfam PF05239 PRC-barrel domain 8 68 1.2E-10 T 06-07-2017 IPR027275 PRC-barrel domain SMD11_RS28195 cae73f991628f9b17351a4fce37e5196 128 Gene3D G3DSA:2.30.30.240 8 49 1.6E-5 T 06-07-2017 SMD11_RS28195 cae73f991628f9b17351a4fce37e5196 128 SUPERFAMILY SSF50346 5 107 3.77E-24 T 06-07-2017 IPR011033 PRC-barrel-like SMD11_RS34120 a21333585c5472256cf1c6f5860ec86a 117 Pfam PF13546 DDE superfamily endonuclease 24 116 2.1E-15 T 06-07-2017 SMD11_RS26375 07d44cc3a911d2cf86b0e04fa52d0022 307 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 18 307 1.7E-100 T 06-07-2017 IPR022292 Conserved hypothetical protein CHP03843 SMD11_RS31710 8a47198e7240e3d1719b1ea4a7f109df 202 Pfam PF13280 WYL domain 2 169 7.6E-24 T 06-07-2017 IPR026881 WYL domain SMD11_RS24275 4ef025a849b3bb8823881cede217c39d 416 SUPERFAMILY SSF55486 262 393 2.67E-5 T 06-07-2017 SMD11_RS17700 9b95ae093d2f7f34d5aeeb0e3a3fe352 172 ProDom PD339375 PRECURSOR SIGNAL SCO3656 SCO2458 CGL2705 MB2629 RV2598/MT2673.1 13 155 6.0E-63 T 06-07-2017 IPR024486 Protein of unknown function DUF2617 SMD11_RS17700 9b95ae093d2f7f34d5aeeb0e3a3fe352 172 Pfam PF10936 Protein of unknown function DUF2617 3 164 5.5E-61 T 06-07-2017 IPR024486 Protein of unknown function DUF2617 SMD11_RS15140 0b81d9c6874324c7c549e74dbbf07e47 438 Pfam PF02397 Bacterial sugar transferase 211 376 1.8E-22 T 06-07-2017 IPR003362 Bacterial sugar transferase SMD11_RS30475 beb83c6d67d4bf4d228c146ca6e5c5ae 342 SUPERFAMILY SSF53901 12 341 3.67E-32 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS30475 beb83c6d67d4bf4d228c146ca6e5c5ae 342 Gene3D G3DSA:3.40.47.10 181 340 1.4E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS30475 beb83c6d67d4bf4d228c146ca6e5c5ae 342 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 203 2.3E-12 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS30475 beb83c6d67d4bf4d228c146ca6e5c5ae 342 Gene3D G3DSA:3.40.47.10 4 180 1.3E-31 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 SMD11_RS30475 beb83c6d67d4bf4d228c146ca6e5c5ae 342 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 266 341 3.7E-11 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SMD11_RS27150 fe55e60e30bdf4165afc0d9aa2300df2 301 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 7 290 1.9E-61 T 06-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 SMD11_RS23145 545d25f9fdd312031f950ad033328243 560 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 43 324 7.5E-50 T 06-07-2017 IPR026588 Choice-of-anchor A domain SMD11_RS23145 545d25f9fdd312031f950ad033328243 560 Pfam PF05738 Cna protein B-type domain 460 529 4.4E-7 T 06-07-2017 IPR008454 Collagen-binding surface protein Cna-like, B-type domain SMD11_RS23145 545d25f9fdd312031f950ad033328243 560 SUPERFAMILY SSF49478 456 529 4.71E-5 T 06-07-2017 SMD11_RS32050 74877adcd38c28d59822b6e6b0c10855 423 Pfam PF06081 Aromatic acid exporter family member 1 30 164 5.8E-11 T 06-07-2017 IPR010343 Aromatic acid exporter family member 1 SMD11_RS14990 5be56d804b26dab62ea28a6cb18fd72f 231 Pfam PF09335 SNARE associated Golgi protein 41 168 3.8E-25 T 06-07-2017 IPR032816 SNARE associated Golgi protein SMD11_RS17210 a32df3e2c54371a408138d51161b676e 186 Pfam PF10759 Protein of unknown function (DUF2587) 34 183 5.3E-79 T 06-07-2017 IPR019695 Bacterial proteasome activator GO:0061136 SMD11_RS00960 4c7002209f2bf2ab903d0c6232770524 326 Pfam PF08310 LGFP repeat 182 230 1.9E-8 T 06-07-2017 IPR013207 LGFP SMD11_RS00960 4c7002209f2bf2ab903d0c6232770524 326 Pfam PF08310 LGFP repeat 234 288 4.7E-16 T 06-07-2017 IPR013207 LGFP SMD11_RS00960 4c7002209f2bf2ab903d0c6232770524 326 Pfam PF08310 LGFP repeat 290 323 2.2E-7 T 06-07-2017 IPR013207 LGFP SMD11_RS07635 632ad99994c41e483cf63c7e64ae620d 419 Pfam PF12307 Protein of unknown function (DUF3631) 184 371 5.0E-68 T 06-07-2017 IPR022081 Domain of unknown function DUF3631 SMD11_RS20485 2091f464fd3da05dfe3cae72e3f7fbdc 444 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 257 374 5.7E-5 T 06-07-2017 IPR005065 Platelet-activating factor acetylhydrolase GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 SMD11_RS20485 2091f464fd3da05dfe3cae72e3f7fbdc 444 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 46 193 4.6E-8 T 06-07-2017 IPR005065 Platelet-activating factor acetylhydrolase GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 SMD11_RS20485 2091f464fd3da05dfe3cae72e3f7fbdc 444 SUPERFAMILY SSF53474 139 420 4.75E-17 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS20485 2091f464fd3da05dfe3cae72e3f7fbdc 444 Gene3D G3DSA:3.40.50.1820 229 431 2.5E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS20485 2091f464fd3da05dfe3cae72e3f7fbdc 444 Gene3D G3DSA:3.40.50.1820 46 93 2.5E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS20485 2091f464fd3da05dfe3cae72e3f7fbdc 444 Gene3D G3DSA:3.40.50.1820 147 194 2.5E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS12700 624090a8a0f801a1b0c597194a89f9c3 218 SUPERFAMILY SSF52540 10 126 7.6E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12700 624090a8a0f801a1b0c597194a89f9c3 218 Gene3D G3DSA:3.40.50.300 20 180 1.5E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS12700 624090a8a0f801a1b0c597194a89f9c3 218 PRINTS PR00988 Uridine kinase signature 18 35 1.5E-7 T 06-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 SMD11_RS12700 624090a8a0f801a1b0c597194a89f9c3 218 PRINTS PR00988 Uridine kinase signature 149 159 1.5E-7 T 06-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 SMD11_RS12700 624090a8a0f801a1b0c597194a89f9c3 218 PRINTS PR00988 Uridine kinase signature 89 104 1.5E-7 T 06-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 SMD11_RS07020 0386a773ffd303313cb8c7b8287b7eb3 370 Pfam PF06224 Winged helix DNA-binding domain 36 353 8.2E-71 T 06-07-2017 IPR009351 Protein of unknown function DUF1006 SMD11_RS09825 790c50dce9eac6a7146b7c1bd143a580 330 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 21 165 4.5E-29 T 06-07-2017 IPR025847 MEDS domain SMD11_RS26770 7bde60d04c36ba67fdc01676b8070ce9 67 Pfam PF08940 Domain of unknown function (DUF1918) 1 57 5.1E-25 T 06-07-2017 IPR015035 Domain of unknown function DUF1918 SMD11_RS26770 7bde60d04c36ba67fdc01676b8070ce9 67 SUPERFAMILY SSF50118 1 63 4.05E-21 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SMD11_RS03925 75061488e925f5f2c9229b8525250741 251 Pfam PF14023 Protein of unknown function (DUF4239) 48 234 5.6E-20 T 06-07-2017 IPR025333 Protein of unknown function DUF4239 SMD11_RS20540 f4c02e71f5039e24456232efcab96806 164 Gene3D G3DSA:3.30.565.10 60 159 8.1E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS20540 f4c02e71f5039e24456232efcab96806 164 Pfam PF13581 Histidine kinase-like ATPase domain 44 150 2.8E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS20540 f4c02e71f5039e24456232efcab96806 164 SUPERFAMILY SSF55874 68 159 3.87E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS05965 b795d3e3811b4b7268bc33d0bac8fd18 114 SUPERFAMILY SSF54060 22 99 1.29E-16 T 06-07-2017 SMD11_RS05965 b795d3e3811b4b7268bc33d0bac8fd18 114 Pfam PF02945 Recombination endonuclease VII 17 96 5.8E-20 T 06-07-2017 IPR004211 Recombination endonuclease VII SMD11_RS30645 7199c2e13bea14ceb32154cbfc502050 434 Pfam PF14378 PAP2 superfamily 159 345 1.7E-20 T 06-07-2017 IPR026841 Inositolphosphotransferase Aur1/Ipt1 SMD11_RS26290 fd9924fb45a3eaaaa0f882e6e5fb8e8e 294 SUPERFAMILY SSF103481 40 119 2.35E-6 T 06-07-2017 SMD11_RS15500 2ad4f6b0e5ce7dbb9fb46f86110c2d47 146 SUPERFAMILY SSF47413 31 76 2.19E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS15500 2ad4f6b0e5ce7dbb9fb46f86110c2d47 146 Gene3D G3DSA:1.10.260.40 27 74 1.1E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SMD11_RS15800 c906632854ef6bcc192e8e2d71fa26c8 98 PIRSF PIRSF006909 1 98 9.7E-58 T 06-07-2017 IPR014447 Uncharacterised conserved protein UCP006909 SMD11_RS30120 7b2cca3517c704b6f51ac82e0603061e 477 Pfam PF02666 Phosphatidylserine decarboxylase 229 448 2.7E-34 T 06-07-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 SMD11_RS20935 16fe3291a004ef867c33660928bb77ff 64 Gene3D G3DSA:3.30.40.10 2 28 2.9E-4 T 06-07-2017 IPR013083 Zinc finger, RING/FYVE/PHD-type SMD11_RS11920 458c87972e0e46f0af4161ad243718d6 247 PIRSF PIRSF006648 1 245 1.6E-17 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SMD11_RS11920 458c87972e0e46f0af4161ad243718d6 247 Pfam PF12698 ABC-2 family transporter protein 48 238 1.1E-12 T 06-07-2017 SMD11_RS05540 ee83a591a80552bb8c72a93805cfd1ef 341 SUPERFAMILY SSF103481 11 113 4.58E-6 T 06-07-2017 SMD11_RS05540 ee83a591a80552bb8c72a93805cfd1ef 341 Pfam PF05653 Magnesium transporter NIPA 27 127 5.7E-9 T 06-07-2017 IPR008521 Magnesium transporter NIPA GO:0015095|GO:0015693|GO:0016021 Reactome: R-HSA-5223345 SMD11_RS02810 081b7f34b28224e61cb957fbc3e969b9 229 TIGRFAM TIGR04032 toxin_SdpC: antimicrobial peptide, SdpC family 49 224 3.3E-30 T 06-07-2017 IPR023888 Antimicrobial peptide, SdpC family SMD11_RS32275 7d267d585515f9a6780716d2f1a468a5 272 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 11 184 1.9E-26 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS32275 7d267d585515f9a6780716d2f1a468a5 272 SUPERFAMILY SSF52266 5 193 7.99E-38 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS32275 7d267d585515f9a6780716d2f1a468a5 272 Gene3D G3DSA:3.40.50.1110 8 194 1.8E-36 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain SMD11_RS28355 4114cf8fb2b8882519bf73da0fce7c9e 300 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 18 261 6.3E-72 T 06-07-2017 IPR014145 DNA ligase D, polymerase domain SMD11_RS24480 e67666e34e117e8cfe2d2adc546e8b63 216 Pfam PF04977 Septum formation initiator 57 99 2.4E-8 T 06-07-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 SMD11_RS16720 fe05463a0af75caf471aa48815853230 264 Gene3D G3DSA:3.40.50.360 10 234 6.7E-72 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS16720 fe05463a0af75caf471aa48815853230 264 SUPERFAMILY SSF52218 10 239 5.19E-68 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS16720 fe05463a0af75caf471aa48815853230 264 Pfam PF02525 Flavodoxin-like fold 10 218 1.6E-56 T 06-07-2017 IPR003680 Flavodoxin-like fold SMD11_RS29260 c152c40b83eaa30394f81d5a09962309 715 Pfam PF13515 Fusaric acid resistance protein-like 398 520 2.8E-10 T 06-07-2017 SMD11_RS29225 0c6ca39db523bb0662c7b5337bfc2abd 224 ProSitePatterns PS00467 Ribosomal protein L2 signature. 38 49 - T 06-07-2017 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SMD11_RS29225 0c6ca39db523bb0662c7b5337bfc2abd 224 Pfam PF12138 Spherulation-specific family 4 15 193 3.7E-32 T 06-07-2017 IPR021986 Spherulation-specific family 4 SMD11_RS19325 9e2f4db9032acb81b7673151519264cd 157 Pfam PF13581 Histidine kinase-like ATPase domain 11 128 5.6E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain SMD11_RS25840 a231b548c14e5029acc548ce713944dc 262 Pfam PF10127 Predicted nucleotidyltransferase 17 253 7.5E-53 T 06-07-2017 IPR018775 Nucleotidyltransferase, predicted SMD11_RS16340 490e64c739c187c6a6726000a6604370 307 Gene3D G3DSA:3.20.20.30 6 305 4.9E-81 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS16340 490e64c739c187c6a6726000a6604370 307 Pfam PF00296 Luciferase-like monooxygenase 9 249 4.0E-56 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS16340 490e64c739c187c6a6726000a6604370 307 SUPERFAMILY SSF51679 4 305 1.44E-73 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SMD11_RS16340 490e64c739c187c6a6726000a6604370 307 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 3 230 3.2E-79 T 06-07-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c SMD11_RS24260 2d3202af6ca9aafac019cb0adc41cb24 459 Pfam PF05991 YacP-like NYN domain 338 457 6.2E-16 T 06-07-2017 IPR010298 Protein of unknown function DUF901 SMD11_RS03170 89bad2fd37c1556ba67b52a53fd86cf7 297 Pfam PF10977 Protein of unknown function (DUF2797) 39 271 3.5E-21 T 06-07-2017 IPR021246 Protein of unknown function DUF2797 SMD11_RS20770 ceb6d55f48b7613259f18a6ce4f86f2a 408 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 271 389 4.8E-8 T 06-07-2017 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain SMD11_RS14315 7fc4e28c7f48f96d723b0f6bfb7cd3a8 540 Pfam PF11209 Protein of unknown function (DUF2993) 226 526 1.5E-25 T 06-07-2017 IPR021373 Protein of unknown function DUF2993 SMD11_RS29290 97838296c91a3b0b9bc391a95c24a81b 413 Pfam PF01699 Sodium/calcium exchanger protein 226 364 2.5E-8 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 SMD11_RS29290 97838296c91a3b0b9bc391a95c24a81b 413 Pfam PF01699 Sodium/calcium exchanger protein 45 192 1.4E-10 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 SMD11_RS12150 a8c6b7e0d337ae3d765b36e53df45aff 186 Pfam PF14030 Protein of unknown function (DUF4245) 9 172 2.3E-47 T 06-07-2017 IPR025339 Protein of unknown function DUF4245 SMD11_RS34610 c09368604eb7e0b289cf54a66a98a643 248 Gene3D G3DSA:1.10.530.10 168 245 1.7E-8 T 06-07-2017 SMD11_RS34610 c09368604eb7e0b289cf54a66a98a643 248 Pfam PF01464 Transglycosylase SLT domain 173 245 1.6E-7 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 SMD11_RS34610 c09368604eb7e0b289cf54a66a98a643 248 SUPERFAMILY SSF53955 141 242 1.09E-13 T 06-07-2017 IPR023346 Lysozyme-like domain SMD11_RS28270 7f8ffe62a7b6dc54d136251e92901d85 131 Pfam PF11236 Protein of unknown function (DUF3037) 13 130 6.3E-40 T 06-07-2017 IPR021398 Protein of unknown function DUF3037 SMD11_RS06780 8107e65a15827b77ae10d7373d4266b0 252 SUPERFAMILY SSF53335 5 230 1.55E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS06780 8107e65a15827b77ae10d7373d4266b0 252 Pfam PF13649 Methyltransferase domain 53 152 6.0E-15 T 06-07-2017 SMD11_RS06780 8107e65a15827b77ae10d7373d4266b0 252 Gene3D G3DSA:3.40.50.150 16 226 3.0E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS18580 cbd49c29f72642c57cae8fda25d7116b 273 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 26 171 1.2E-29 T 06-07-2017 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SMD11_RS28435 e427e578c9f27193ce5798817ed39e1f 235 Pfam PF09335 SNARE associated Golgi protein 81 198 6.9E-26 T 06-07-2017 IPR032816 SNARE associated Golgi protein SMD11_RS24460 dda700e381473fdf000f26a9d9ea0d43 458 Pfam PF01882 Protein of unknown function DUF58 229 307 3.8E-21 T 06-07-2017 IPR002881 Domain of unknown function DUF58 SMD11_RS33835 ff8cb05a194dae84a28ca8e3fdb98925 285 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 25 165 7.8E-10 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 SMD11_RS33835 ff8cb05a194dae84a28ca8e3fdb98925 285 SUPERFAMILY SSF109854 17 172 5.49E-14 T 06-07-2017 SMD11_RS33835 ff8cb05a194dae84a28ca8e3fdb98925 285 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 25 239 1.4E-20 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type SMD11_RS16930 6cdf45f4edfbde31bf2cdb9f69d017b0 180 Hamap MF_00630 UPF0232 protein . 3 166 30.233 T 06-07-2017 IPR023007 Uncharacterised protein family UPF0232, actinobacteria SMD11_RS16930 6cdf45f4edfbde31bf2cdb9f69d017b0 180 Pfam PF05258 Protein of unknown function (DUF721) 65 154 1.0E-24 T 06-07-2017 IPR007922 Protein of unknown function DUF721/UPF0232 SMD11_RS00545 9334983c46f6ecf75c94158c0a595d2a 133 SUPERFAMILY SSF56059 22 118 7.65E-14 T 06-07-2017 SMD11_RS22825 55c0f131a298077a57c3ae482a7c06df 59 Pfam PF04149 Domain of unknown function (DUF397) 6 56 7.7E-13 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS17780 711001a19833d61d43f0eaebb80d7b0f 368 SUPERFAMILY SSF111331 208 366 1.68E-8 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMD11_RS17780 711001a19833d61d43f0eaebb80d7b0f 368 SUPERFAMILY SSF111331 11 134 1.68E-8 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain SMD11_RS33170 184218a5e205868baf3c5bee5be8568d 370 Gene3D G3DSA:2.60.120.260 237 368 7.0E-7 T 06-07-2017 IPR008979 Galactose-binding domain-like SMD11_RS29865 c9358c64c73afe0edc0b76f41e8c4346 197 Gene3D G3DSA:3.40.50.360 10 187 8.5E-50 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS29865 c9358c64c73afe0edc0b76f41e8c4346 197 Pfam PF03358 NADPH-dependent FMN reductase 10 153 4.1E-40 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SMD11_RS29865 c9358c64c73afe0edc0b76f41e8c4346 197 SUPERFAMILY SSF52218 10 169 1.13E-40 T 06-07-2017 IPR029039 Flavoprotein-like domain SMD11_RS10625 0894e2c1ed2baee7f6a0ba003a67e9dd 114 Pfam PF12823 Domain of unknown function (DUF3817) 9 95 7.6E-24 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane SMD11_RS10625 0894e2c1ed2baee7f6a0ba003a67e9dd 114 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 13 93 1.1E-23 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane SMD11_RS17305 0f3d15b9316791939f21f404f2240348 202 Pfam PF07282 Putative transposase DNA-binding domain 110 164 3.7E-11 T 06-07-2017 IPR010095 Transposase IS605, OrfB, C-terminal SMD11_RS28760 dcc7bab7becd0bf2089a3b03b1bf67e2 230 SUPERFAMILY SSF53335 40 220 4.49E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS28760 dcc7bab7becd0bf2089a3b03b1bf67e2 230 Gene3D G3DSA:3.40.50.150 29 197 1.0E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS28760 dcc7bab7becd0bf2089a3b03b1bf67e2 230 Pfam PF08241 Methyltransferase domain 51 143 1.2E-17 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SMD11_RS31520 ea98d5414995c5b8c1a9f2d6e6168385 466 SUPERFAMILY SSF52777 84 193 7.78E-5 T 06-07-2017 SMD11_RS31520 ea98d5414995c5b8c1a9f2d6e6168385 466 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 104 211 1.2E-10 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 SMD11_RS01960 5214b16ca27355e8057c49946fe61e89 159 Pfam PF07510 Protein of unknown function (DUF1524) 38 151 1.5E-7 T 06-07-2017 IPR011089 Domain of unknown function DUF1524 SMD11_RS17140 5d1837033cf827c0938e54e48c70d9bc 407 SMART SM00752 20 369 2.2E-76 T 06-07-2017 IPR011020 HTTM Reactome: R-HSA-159740 SMD11_RS14825 4c7e2d5174060f789ee9452dc929b2e9 131 Gene3D G3DSA:1.10.10.10 3 80 1.2E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14825 4c7e2d5174060f789ee9452dc929b2e9 131 SUPERFAMILY SSF46785 3 115 7.55E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS14825 4c7e2d5174060f789ee9452dc929b2e9 131 Pfam PF03965 Penicillinase repressor 5 114 1.6E-23 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SMD11_RS14250 5a00b394c432b0e27c08679b2c28dc1b 164 Pfam PF01391 Collagen triple helix repeat (20 copies) 109 163 7.8E-10 T 06-07-2017 IPR008160 Collagen triple helix repeat SMD11_RS21400 e695e3c5ce12e925c8e792518cb86db8 289 SUPERFAMILY SSF56529 66 283 3.53E-71 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD11_RS21400 e695e3c5ce12e925c8e792518cb86db8 289 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 281 5.2E-67 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD11_RS21400 e695e3c5ce12e925c8e792518cb86db8 289 Gene3D G3DSA:3.90.850.10 68 284 2.6E-80 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 SMD11_RS24845 ab7bb32ebb77863a9f8a34123ba0ccf9 1033 Pfam PF12905 Endo-alpha-N-acetylgalactosaminidase 284 670 6.9E-166 T 06-07-2017 IPR025706 Endo-alpha-N-acetylgalactosaminidase GO:0033926 SMD11_RS30040 f40b1dd82300b06d51a38b8316954d7a 236 Pfam PF14016 Protein of unknown function (DUF4232) 99 233 4.5E-27 T 06-07-2017 IPR025326 Protein of unknown function DUF4232 SMD11_RS03900 e692d0a0792e85c8e2469610c04be7af 200 Pfam PF16157 Domain of unknown function (DUF4865) 1 187 2.5E-68 T 06-07-2017 IPR032349 Protein of unknown function DUF4865 SMD11_RS15310 b706c82a57b5c7b109ee4038f87e1203 110 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 2 101 4.4E-24 T 06-07-2017 IPR021202 Helicase/secretion neighbourhood TadE-like protein SMD11_RS15310 b706c82a57b5c7b109ee4038f87e1203 110 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 2 46 9.0E-5 T 06-07-2017 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal SMD11_RS12130 59502f32f361db5fa26632e19bdba326 453 PIRSF PIRSF006060 1 445 2.5E-51 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SMD11_RS12130 59502f32f361db5fa26632e19bdba326 453 Pfam PF00324 Amino acid permease 36 418 5.7E-31 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SMD11_RS09760 07477bf023198ebddd9e0bc3570dbb51 166 Pfam PF12028 Protein of unknown function (DUF3515) 26 162 2.0E-23 T 06-07-2017 IPR021903 Protein of unknown function DUF3515 SMD11_RS12825 9a5251038741e6109058b5026998a1db 368 Pfam PF02653 Branched-chain amino acid transport system / permease component 58 332 1.9E-43 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SMD11_RS00500 654361e688d9f15e2f4454b042a0f926 135 Pfam PF13471 Transglutaminase-like superfamily 20 116 4.2E-7 T 06-07-2017 IPR032708 Microcin J25-processing protein McjB, C-terminal SMD11_RS13715 09bd63ec57e9a1f6db7722aad523dfb9 88 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 19 85 2.6E-11 T 06-07-2017 IPR008792 Coenzyme PQQ synthesis D SMD11_RS23290 e9d77402920918e3c2f990d3a085b739 376 Pfam PF04332 Protein of unknown function (DUF475) 44 361 1.3E-141 T 06-07-2017 IPR007427 Protein of unknown function DUF475 SMD11_RS08430 9e633586b65b6fce74cd83df9c52f410 390 Pfam PF01474 Class-II DAHP synthetase family 9 165 2.0E-47 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMD11_RS08430 9e633586b65b6fce74cd83df9c52f410 390 Pfam PF01474 Class-II DAHP synthetase family 181 384 1.2E-80 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 SMD11_RS08430 9e633586b65b6fce74cd83df9c52f410 390 SUPERFAMILY SSF51569 8 388 1.98E-142 T 06-07-2017 SMD11_RS08095 2e6806c65e33a088e9dcb1376fe026eb 476 Pfam PF03559 NDP-hexose 2,3-dehydratase 273 471 9.4E-62 T 06-07-2017 IPR005212 NDP-hexose 2,3-dehydratase SMD11_RS08095 2e6806c65e33a088e9dcb1376fe026eb 476 Pfam PF03559 NDP-hexose 2,3-dehydratase 38 239 5.4E-77 T 06-07-2017 IPR005212 NDP-hexose 2,3-dehydratase SMD11_RS23820 1f164086d12de82952edd61b670dc062 72 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 70 7.7E-26 T 06-07-2017 IPR018735 Protein of unknown function DUF2277 SMD11_RS14880 a906d555d2e15c5dad0c9a50aae193b3 338 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 106 251 7.9E-12 T 06-07-2017 IPR003788 Putative S-adenosyl-L-methionine-dependent methyltransferase MidA Reactome: R-HSA-6799198 SMD11_RS14880 a906d555d2e15c5dad0c9a50aae193b3 338 SUPERFAMILY SSF53335 3 321 1.26E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS21105 79a247b7571260d8356485294369f972 350 Pfam PF03601 Conserved hypothetical protein 698 27 330 1.6E-64 T 06-07-2017 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 SMD11_RS16400 d0a3860528e82ecb587e162daa5730fa 334 Pfam PF03756 A-factor biosynthesis hotdog domain 31 171 4.2E-26 T 06-07-2017 IPR005509 A-factor biosynthesis hotdog domain SMD11_RS16400 d0a3860528e82ecb587e162daa5730fa 334 Pfam PF03756 A-factor biosynthesis hotdog domain 208 333 7.7E-12 T 06-07-2017 IPR005509 A-factor biosynthesis hotdog domain SMD11_RS06690 3df1401d8aa2139283cbe346b2b8967e 395 Pfam PF11991 Tryptophan dimethylallyltransferase 93 349 1.1E-6 T 06-07-2017 IPR017795 Aromatic prenyltransferase, DMATS type GO:0009820|GO:0050364 SMD11_RS12730 34d996097f14a8c8cee22e99e35e3570 70 Pfam PF04024 PspC domain 5 59 2.9E-17 T 06-07-2017 IPR007168 Phage shock protein, PspC, N-terminal SMD11_RS30175 f4d72c0bc27f908fc7386dfac99c9502 228 Pfam PF13628 Domain of unknown function (DUF4142) 80 212 6.8E-18 T 06-07-2017 IPR025419 Domain of unknown function DUF4142 SMD11_RS02100 927407704d3e97a8a73d38f6562d7698 269 Pfam PF05988 Bacterial protein of unknown function (DUF899) 15 210 1.9E-57 T 06-07-2017 IPR010296 Protein of unknown function DUF899, thioredoxin-like SMD11_RS01895 0aa492eae3f7abdfd2d58683a64eab4b 205 SUPERFAMILY SSF47203 90 181 4.19E-7 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SMD11_RS02370 e481843da6ad641ff196bce079c5306e 263 Pfam PF03591 AzlC protein 51 186 2.4E-32 T 06-07-2017 IPR011606 Branched-chain amino acid transport, permease SMD11_RS27710 87c6f4515ddd9907d492e4b32cf983b5 517 SUPERFAMILY SSF52540 187 325 2.99E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS17880 55ba6455b775cefd016dcd1d3ec4dccd 256 Pfam PF01061 ABC-2 type transporter 11 218 1.9E-20 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD11_RS02765 b68e25c4871d23b37fcab46de13ea060 297 SUPERFAMILY SSF103481 39 121 7.59E-5 T 06-07-2017 SMD11_RS00140 cafef27fd32a3708ab9d27ac64319657 126 Pfam PF03995 Peptidase inhibitor family I36 34 106 8.1E-18 T 06-07-2017 SMD11_RS20235 79a5181d4d79ec04c8ac30b93ef880b1 488 Pfam PF09852 Predicted membrane protein (DUF2079) 55 436 3.5E-61 T 06-07-2017 IPR018650 Sulfolobus virus STSV1, Orf64 SMD11_RS14310 2eeacc5472a7e7316052ddebf09f305b 432 SUPERFAMILY SSF103473 33 416 5.41E-28 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS14310 2eeacc5472a7e7316052ddebf09f305b 432 Gene3D G3DSA:1.20.1250.20 225 415 1.0E-11 T 06-07-2017 SMD11_RS14310 2eeacc5472a7e7316052ddebf09f305b 432 Gene3D G3DSA:1.20.1250.20 30 201 1.4E-13 T 06-07-2017 SMD11_RS14310 2eeacc5472a7e7316052ddebf09f305b 432 Pfam PF07690 Major Facilitator Superfamily 41 364 4.1E-15 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SMD11_RS02990 573768150d51f72783fbb96ed6e56779 496 Pfam PF00916 Sulfate permease family 12 378 1.5E-62 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 SMD11_RS11710 ed25876d33af741244f32a523ee19be6 76 Pfam PF11305 Protein of unknown function (DUF3107) 1 72 5.2E-29 T 06-07-2017 IPR021456 Protein of unknown function DUF3107 SMD11_RS31040 636ce9cb6e0bffe14ba8fcc69fe8b478 447 SUPERFAMILY SSF56059 280 430 2.22E-23 T 06-07-2017 SMD11_RS31040 636ce9cb6e0bffe14ba8fcc69fe8b478 447 SUPERFAMILY SSF56059 36 174 2.22E-23 T 06-07-2017 SMD11_RS03500 de121f70d979f4ccb01ff1ccbf46cf83 501 Pfam PF13515 Fusaric acid resistance protein-like 194 319 5.7E-16 T 06-07-2017 SMD11_RS16005 218d3a508525300a903a983e0d083eed 74 Pfam PF04149 Domain of unknown function (DUF397) 12 67 1.3E-20 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS25905 996d040f75947ab848c192e9bbc751bc 66 Pfam PF00741 Gas vesicle protein 2 39 1.8E-13 T 06-07-2017 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 SMD11_RS15240 0b49bc98acf85c5808f28625f3680857 410 Pfam PF12307 Protein of unknown function (DUF3631) 175 362 1.3E-68 T 06-07-2017 IPR022081 Domain of unknown function DUF3631 SMD11_RS13405 deed771031289bba0c1c6bf6f624b8e5 222 Pfam PF13349 Putative adhesin 60 219 1.5E-8 T 06-07-2017 IPR025164 Putative adhesin SMD11_RS06965 b97e3f5878648d161dbaf7234ec1e1a6 83 Gene3D G3DSA:3.30.70.930 21 77 1.3E-5 T 06-07-2017 IPR029756 MTH1187/YkoF-like SMD11_RS06965 b97e3f5878648d161dbaf7234ec1e1a6 83 SUPERFAMILY SSF89957 3 77 1.7E-7 T 06-07-2017 IPR029756 MTH1187/YkoF-like SMD11_RS28860 94210b7a220218901fc32b044b4c7e24 316 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 38 281 4.5E-85 T 06-07-2017 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related SMD11_RS26355 cb57c7794bcbbc4c13c228d16a9dc70f 262 SUPERFAMILY SSF47240 15 186 2.78E-10 T 06-07-2017 IPR009078 Ferritin-like superfamily SMD11_RS07510 214a58e4bdac622732e9f91c5e0cd2f8 132 Gene3D G3DSA:3.40.50.1010 57 116 2.1E-7 T 06-07-2017 IPR029060 PIN domain-like SMD11_RS15210 cb246340abda72f14acb67ba47810849 726 Gene3D G3DSA:3.40.50.300 240 445 5.3E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMD11_RS10695 5648de06acbb1b43638a7561e95fd5b3 256 Pfam PF12730 ABC-2 family transporter protein 8 188 1.4E-8 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 SMD11_RS20810 e59fbb9aea96c4155bd579c65148440f 403 Pfam PF06224 Winged helix DNA-binding domain 45 378 6.6E-63 T 06-07-2017 IPR009351 Protein of unknown function DUF1006 SMD11_RS23620 a32556ad671b8a556901edf4f82d6f0c 278 Pfam PF02591 C4-type zinc ribbon domain 236 270 1.8E-11 T 06-07-2017 IPR003743 C4-type zinc ribbon domain SMD11_RS19795 5d713f1aca1b7a9ac68a0f03953bf59a 262 Pfam PF01988 VIT family 47 254 8.1E-56 T 06-07-2017 IPR008217 Ccc1 family SMD11_RS22235 92219d2b2ea4f4ea621d5cfbc7f67cde 200 PIRSF PIRSF016661 19 199 1.6E-37 T 06-07-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 SMD11_RS22235 92219d2b2ea4f4ea621d5cfbc7f67cde 200 Pfam PF02632 BioY family 55 194 5.5E-31 T 06-07-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 SMD11_RS01095 570e5ff671a1f2ca4d89c5e38aa1e652 155 Gene3D G3DSA:1.10.10.10 16 147 4.6E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS01095 570e5ff671a1f2ca4d89c5e38aa1e652 155 SUPERFAMILY SSF46785 17 150 8.99E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS05575 e78c9639f52f6244834ab78a730cf22b 130 Pfam PF07681 DoxX 11 90 1.9E-11 T 06-07-2017 IPR032808 DoxX family SMD11_RS20260 aac36f9e9ae70a6d9edac663add07928 205 Pfam PF13624 SurA N-terminal domain 12 148 1.5E-11 T 06-07-2017 SMD11_RS20260 aac36f9e9ae70a6d9edac663add07928 205 SUPERFAMILY SSF109998 32 150 3.92E-12 T 06-07-2017 IPR027304 Trigger factor/SurA domain SMD11_RS12445 c36c743be1a64cf6aaae5e315f315f7a 136 Pfam PF14155 Domain of unknown function (DUF4307) 22 130 1.0E-24 T 06-07-2017 IPR025443 Protein of unknown function DUF4307 SMD11_RS15330 7f9856b4bea1cac972c08ad7fd982e39 296 Pfam PF00482 Type II secretion system (T2SS), protein F 129 248 1.3E-9 T 06-07-2017 IPR018076 Type II secretion system F domain SMD11_RS19210 fe02eb0890fb342bbf93f3c5b35aaa05 402 Pfam PF09445 RNA cap guanine-N2 methyltransferase 111 170 8.4E-8 T 06-07-2017 IPR019012 RNA cap guanine-N2 methyltransferase GO:0001510|GO:0008168|GO:0009452 Reactome: R-HSA-1368082|Reactome: R-HSA-1368108|Reactome: R-HSA-191859|Reactome: R-HSA-1989781|Reactome: R-HSA-2032785|Reactome: R-HSA-2151201|Reactome: R-HSA-2426168|Reactome: R-HSA-381340|Reactome: R-HSA-400206|Reactome: R-HSA-400253 SMD11_RS19210 fe02eb0890fb342bbf93f3c5b35aaa05 402 SUPERFAMILY SSF53335 74 237 1.78E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS19210 fe02eb0890fb342bbf93f3c5b35aaa05 402 Gene3D G3DSA:3.40.50.150 79 188 1.9E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SMD11_RS29010 c63dd503eead0fb60434abd1a416ede0 58 TIGRFAM TIGR03892 thiopep_precurs: thiazolylpeptide-type bacteriocin precursor 15 56 2.2E-13 T 06-07-2017 IPR023895 Thiazolylpeptide-type bacteriocin precursor SMD11_RS21375 2b7f6027543b4caec57a472a4d17080c 513 Pfam PF00474 Sodium:solute symporter family 49 445 2.2E-20 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 SMD11_RS15320 299d0a35d8c64470a41796db63da5bf5 79 Pfam PF14029 Protein of unknown function (DUF4244) 27 76 5.5E-25 T 06-07-2017 IPR025338 Protein of unknown function DUF4244 SMD11_RS13850 82333c2a3d70cc44d7353adb3466fd38 878 Pfam PF13625 Helicase conserved C-terminal domain 584 706 2.7E-41 T 06-07-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 SMD11_RS22390 35274d484a955c4ce61ee5b8698ffd86 121 Pfam PF14017 Protein of unknown function (DUF4233) 2 105 1.2E-31 T 06-07-2017 IPR025327 Protein of unknown function DUF4233 SMD11_RS28155 d45d2d79be7f6ec6624cbe558c527b4d 296 Pfam PF05949 Bacterial protein of unknown function (DUF881) 137 280 1.0E-38 T 06-07-2017 IPR010273 Protein of unknown function DUF881 SMD11_RS00180 0cd2c2595e1e866c067ef63e5fe2256c 201 Pfam PF06271 RDD family 8 185 8.1E-14 T 06-07-2017 IPR010432 RDD SMD11_RS20305 6630854208d1e740a4369d7100fb6afe 176 Pfam PF04417 Protein of unknown function (DUF501) 36 156 2.2E-35 T 06-07-2017 IPR007511 Protein of unknown function DUF501 SMD11_RS04680 e88976bbe4709a9862e3e07283f1de27 209 Pfam PF16316 Domain of unknown function (DUF4956) 14 182 8.8E-54 T 06-07-2017 IPR032531 Protein of unknown function DUF4956 SMD11_RS11315 f867599568b7b3d9187cecdb52bdc51a 61 Pfam PF08410 Domain of unknown function (DUF1737) 11 56 4.5E-18 T 06-07-2017 IPR013619 Domain of unknown function DUF1737 SMD11_RS03920 5525fb89677aaa8eaf6c041eac39357a 240 PRINTS PR01217 Proline rich extensin signature 50 66 5.2E-10 T 06-07-2017 SMD11_RS03920 5525fb89677aaa8eaf6c041eac39357a 240 PRINTS PR01217 Proline rich extensin signature 35 47 5.2E-10 T 06-07-2017 SMD11_RS03920 5525fb89677aaa8eaf6c041eac39357a 240 PRINTS PR01217 Proline rich extensin signature 122 138 5.2E-10 T 06-07-2017 SMD11_RS03920 5525fb89677aaa8eaf6c041eac39357a 240 PRINTS PR01217 Proline rich extensin signature 146 163 5.2E-10 T 06-07-2017 SMD11_RS03920 5525fb89677aaa8eaf6c041eac39357a 240 PRINTS PR01217 Proline rich extensin signature 165 190 5.2E-10 T 06-07-2017 SMD11_RS27505 27c1d7b4d8f70cfd509c78164413af18 218 Pfam PF04973 Nicotinamide mononucleotide transporter 21 201 7.0E-43 T 06-07-2017 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 SMD11_RS12670 2840f163f05d2c35a0fca16161ed19b7 215 Pfam PF10756 Bacterial PH domain 76 176 1.5E-9 T 06-07-2017 IPR019692 Protein of unknown function DUF2581 SMD11_RS02425 a1e78c27731f8dfa51cae3ef1797d234 196 Pfam PF08877 MepB protein 50 170 1.5E-47 T 06-07-2017 IPR011235 MepB-like SMD11_RS21260 38c232241f6e058a2754b91fd37aaf1d 129 Gene3D G3DSA:3.40.50.720 45 127 5.4E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain SMD11_RS03125 555458791551bea3be70df4548065943 777 SUPERFAMILY SSF53474 579 690 2.33E-9 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold SMD11_RS06810 adbc6ae6748d8379ff9646ec66e9eb60 301 Gene3D G3DSA:1.10.101.10 230 292 1.4E-6 T 06-07-2017 IPR002477 Peptidoglycan binding-like SMD11_RS06810 adbc6ae6748d8379ff9646ec66e9eb60 301 SUPERFAMILY SSF47090 230 292 5.89E-7 T 06-07-2017 IPR002477 Peptidoglycan binding-like SMD11_RS18230 3f08ebea427a95d14a82750fe9fa9363 271 Pfam PF15698 Phosphatase 7 269 1.1E-113 T 06-07-2017 IPR031423 Uncharacterised phosphatase SCO2771 SMD11_RS00310 d1fbe8eb57e7cd2cf476f2a02d35f857 136 SUPERFAMILY SSF55961 1 127 1.34E-7 T 06-07-2017 SMD11_RS27665 40e95468af2985b860d883221a5cd078 371 Gene3D G3DSA:3.10.150.10 2 131 1.5E-4 T 06-07-2017 SMD11_RS07155 303236a4d0a81dd39dad02b337f603a9 161 Pfam PF04306 Protein of unknown function (DUF456) 21 156 1.1E-28 T 06-07-2017 IPR007403 Protein of unknown function DUF456 SMD11_RS06790 6b9433eba3f7248327ce24903bcf0a1f 374 SUPERFAMILY SSF103473 6 358 7.72E-14 T 06-07-2017 IPR020846 Major facilitator superfamily domain SMD11_RS12335 8c457b0d6b57e7bb5935613f26137162 207 Pfam PF07811 TadE-like protein 79 121 8.1E-8 T 06-07-2017 IPR012495 TadE-like SMD11_RS04990 04e326982ca01df3e070a829fe04e40a 315 Gene3D G3DSA:1.10.443.10 143 253 1.1E-4 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SMD11_RS34555 831fa135f4b7fe8d240e388c36122094 70 Pfam PF07362 Post-segregation antitoxin CcdA 5 63 1.5E-6 T 06-07-2017 IPR009956 Post-segregation antitoxin CcdA SMD11_RS14615 9775ac157f360113ad48ea9ba7bb5532 69 Pfam PF04149 Domain of unknown function (DUF397) 15 57 4.0E-4 T 06-07-2017 IPR007278 Domain of unknown function DUF397 SMD11_RS19685 ac9351654f1e555d4ff450a89384ce20 375 Pfam PF14027 Protein of unknown function (DUF4243) 41 346 6.2E-27 T 06-07-2017 IPR025337 Domain of unknown function DUF4243 SMD11_RS21635 4f7c51e34090bcd5d2e55b0a3fde8d54 333 Pfam PF14378 PAP2 superfamily 46 233 3.2E-59 T 06-07-2017 IPR026841 Inositolphosphotransferase Aur1/Ipt1 SMD11_RS16490 60db765e67d0e9d424b5c9576090840d 299 Pfam PF12679 ABC-2 family transporter protein 90 297 2.9E-7 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 SMD11_RS25950 65aff9d3635037aff90a81d22a7b95c8 391 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 99 239 1.7E-6 T 06-07-2017 SMD11_RS33380 61bdcddd17c9827b6fe15ba19676f24e 208 Gene3D G3DSA:1.10.10.10 7 61 3.6E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain SMD11_RS15325 01ddddf4cad7c9542f2cd5cb5572eec0 266 Pfam PF00482 Type II secretion system (T2SS), protein F 127 251 1.3E-15 T 06-07-2017 IPR018076 Type II secretion system F domain SMD11_RS21990 f211ee030940d17822c43f09547b6c2e 280 Pfam PF13349 Putative adhesin 77 275 1.7E-8 T 06-07-2017 IPR025164 Putative adhesin SMD11_RS24650 5784cd570c1f6db563208a2dcd7f7ce3 249 Pfam PF01061 ABC-2 type transporter 24 209 3.2E-9 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SMD11_RS04825 c1fb5b6d312670a5d8c784bb8d297acb 278 Pfam PF13349 Putative adhesin 56 249 1.8E-11 T 06-07-2017 IPR025164 Putative adhesin SMD11_RS17545 d81b7456c04dc0500e79ca5516625915 175 Pfam PF14016 Protein of unknown function (DUF4232) 40 166 7.1E-19 T 06-07-2017 IPR025326 Protein of unknown function DUF4232 SMD11_RS27105 120c772b5ec36cf6a0688f69103a38e4 189 Pfam PF14280 Domain of unknown function (DUF4365) 34 182 1.4E-25 T 06-07-2017 IPR025375 Domain of unknown function DUF4365